{
  "dbId" : 10099941,
  "stableId" : "R-MMU-2142700",
  "displayName" : "Biosynthesis of Lipoxins (LX)",
  "nodes" : [ {
    "id" : 30625,
    "reactomeId" : 2161759,
    "displayName" : "LXA4",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 511,
      "y" : 528
    },
    "minX" : 484,
    "maxX" : 580,
    "minY" : 512,
    "maxY" : 543,
    "prop" : {
      "x" : 484,
      "y" : 513,
      "width" : 54,
      "height" : 30
    },
    "textPosition" : {
      "x" : 492,
      "y" : 517
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 533,
          "y" : 518
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 533,
          "y" : 518
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30624,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 541,
          "y" : 527
        },
        "to" : {
          "x" : 580,
          "y" : 527
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 30626,
    "reactomeId" : 29360,
    "displayName" : "NAD+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 569,
      "y" : 503
    },
    "minX" : 542,
    "maxX" : 597,
    "minY" : 487,
    "maxY" : 527,
    "prop" : {
      "x" : 542,
      "y" : 488,
      "width" : 54,
      "height" : 30
    },
    "textPosition" : {
      "x" : 547,
      "y" : 492
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 591,
          "y" : 493
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 591,
          "y" : 493
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30624,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 575,
          "y" : 521
        },
        "to" : {
          "x" : 580,
          "y" : 527
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 30627,
    "reactomeId" : 2142761,
    "displayName" : "15k-LXA4",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 782,
      "y" : 528
    },
    "minX" : 684,
    "maxX" : 829,
    "minY" : 512,
    "maxY" : 543,
    "prop" : {
      "x" : 736,
      "y" : 513,
      "width" : 92,
      "height" : 30
    },
    "textPosition" : {
      "x" : 750,
      "y" : 517
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 823,
          "y" : 518
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 823,
          "y" : 518
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30624,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 733,
          "y" : 527
        },
        "to" : {
          "x" : 684,
          "y" : 527
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 726,
          "y" : 531
        },
        "b" : {
          "x" : 733,
          "y" : 527
        },
        "c" : {
          "x" : 726,
          "y" : 523
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 726,
          "y" : 523
        }
      }
    } ]
  }, {
    "id" : 30628,
    "reactomeId" : 73473,
    "displayName" : "NADH",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 698,
      "y" : 580
    },
    "minX" : 671,
    "maxX" : 726,
    "minY" : 527,
    "maxY" : 595,
    "prop" : {
      "x" : 671,
      "y" : 565,
      "width" : 54,
      "height" : 30
    },
    "textPosition" : {
      "x" : 676,
      "y" : 569
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 720,
          "y" : 570
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 720,
          "y" : 570
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30624,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 694,
          "y" : 562
        },
        "to" : {
          "x" : 684,
          "y" : 527
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 688,
          "y" : 556
        },
        "b" : {
          "x" : 694,
          "y" : 562
        },
        "c" : {
          "x" : 696,
          "y" : 554
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 696,
          "y" : 554
        }
      }
    } ]
  }, {
    "id" : 30629,
    "reactomeId" : 70106,
    "displayName" : "H+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 704,
      "y" : 490
    },
    "minX" : 684,
    "maxX" : 723,
    "minY" : 474,
    "maxY" : 527,
    "prop" : {
      "x" : 687,
      "y" : 475,
      "width" : 35,
      "height" : 30
    },
    "textPosition" : {
      "x" : 691,
      "y" : 479
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 717,
          "y" : 480
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 717,
          "y" : 480
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30624,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 695,
          "y" : 508
        },
        "to" : {
          "x" : 684,
          "y" : 527
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 695,
          "y" : 516
        },
        "b" : {
          "x" : 695,
          "y" : 508
        },
        "c" : {
          "x" : 688,
          "y" : 512
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 688,
          "y" : 512
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 30630,
    "reactomeId" : 10042676,
    "displayName" : "HPGD dimer",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 624,
      "y" : 465
    },
    "minX" : 578,
    "maxX" : 677,
    "minY" : 448,
    "maxY" : 519,
    "prop" : {
      "x" : 578,
      "y" : 454,
      "width" : 93,
      "height" : 22
    },
    "textPosition" : {
      "x" : 583,
      "y" : 455
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 671,
          "y" : 454
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 671,
          "y" : 454
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30624,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 624,
          "y" : 479
        },
        "to" : {
          "x" : 624,
          "y" : 511
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 624,
          "y" : 515
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 624,
          "y" : 515
        }
      }
    } ]
  }, {
    "id" : 30632,
    "reactomeId" : 266010,
    "displayName" : "5S-HpETE",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 102,
      "y" : 302
    },
    "minX" : 65,
    "maxX" : 140,
    "minY" : 286,
    "maxY" : 317,
    "prop" : {
      "x" : 65,
      "y" : 287,
      "width" : 74,
      "height" : 30
    },
    "textPosition" : {
      "x" : 68,
      "y" : 291
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 134,
          "y" : 292
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 134,
          "y" : 292
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30631,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 30633,
    "reactomeId" : 265281,
    "displayName" : "LTA4",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 366,
      "y" : 301
    },
    "minX" : 255,
    "maxX" : 394,
    "minY" : 285,
    "maxY" : 316,
    "prop" : {
      "x" : 339,
      "y" : 286,
      "width" : 54,
      "height" : 30
    },
    "textPosition" : {
      "x" : 347,
      "y" : 290
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 388,
          "y" : 291
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 388,
          "y" : 291
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30631,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 336,
          "y" : 301
        },
        "to" : {
          "x" : 255,
          "y" : 301
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 329,
          "y" : 305
        },
        "b" : {
          "x" : 336,
          "y" : 301
        },
        "c" : {
          "x" : 329,
          "y" : 297
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 329,
          "y" : 297
        }
      }
    } ]
  }, {
    "id" : 30634,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 286,
      "y" : 336
    },
    "minX" : 255,
    "maxX" : 309,
    "minY" : 301,
    "maxY" : 351,
    "prop" : {
      "x" : 265,
      "y" : 321,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 269,
      "y" : 325
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 303,
          "y" : 326
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 303,
          "y" : 326
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30631,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 272,
          "y" : 318
        },
        "to" : {
          "x" : 255,
          "y" : 301
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 264,
          "y" : 316
        },
        "b" : {
          "x" : 272,
          "y" : 318
        },
        "c" : {
          "x" : 270,
          "y" : 310
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 270,
          "y" : 310
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 30636,
    "reactomeId" : 2142776,
    "displayName" : "LXB4",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 636,
      "y" : 63
    },
    "minX" : 556,
    "maxX" : 660,
    "minY" : 47,
    "maxY" : 79,
    "prop" : {
      "x" : 613,
      "y" : 48,
      "width" : 46,
      "height" : 31
    },
    "textPosition" : {
      "x" : 617,
      "y" : 53
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 654,
          "y" : 53
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 654,
          "y" : 53
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30635,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 556,
            "y" : 55
          },
          "b" : {
            "x" : 568,
            "y" : 67
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 562,
            "y" : 61
          }
        }
      }
    } ]
  }, {
    "id" : 30611,
    "reactomeId" : 29356,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 336,
      "y" : 75
    },
    "minX" : 315,
    "maxX" : 480,
    "minY" : 59,
    "maxY" : 111,
    "prop" : {
      "x" : 315,
      "y" : 60,
      "width" : 43,
      "height" : 31
    },
    "textPosition" : {
      "x" : 319,
      "y" : 65
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 353,
          "y" : 65
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 353,
          "y" : 65
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30610,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 361,
          "y" : 80
        },
        "to" : {
          "x" : 479,
          "y" : 111
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 414,
            "y" : 89
          },
          "b" : {
            "x" : 426,
            "y" : 101
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 420,
            "y" : 95
          }
        }
      }
    }, {
      "edgeId" : 30635,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 361,
          "y" : 72
        },
        "to" : {
          "x" : 480,
          "y" : 61
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 414,
            "y" : 60
          },
          "b" : {
            "x" : 426,
            "y" : 72
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 420,
            "y" : 66
          }
        }
      }
    } ],
    "trivial" : true
  }, {
    "id" : 30612,
    "reactomeId" : 9032038,
    "displayName" : "LTA4",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 409,
      "y" : 131
    },
    "minX" : 386,
    "maxX" : 480,
    "minY" : 61,
    "maxY" : 146,
    "prop" : {
      "x" : 386,
      "y" : 116,
      "width" : 47,
      "height" : 30
    },
    "textPosition" : {
      "x" : 391,
      "y" : 120
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 428,
          "y" : 121
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 428,
          "y" : 121
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30610,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 436,
          "y" : 124
        },
        "to" : {
          "x" : 479,
          "y" : 111
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 451,
            "y" : 111
          },
          "b" : {
            "x" : 463,
            "y" : 123
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 457,
            "y" : 117
          }
        }
      }
    }, {
      "edgeId" : 30635,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 424,
          "y" : 113
        },
        "to" : {
          "x" : 480,
          "y" : 61
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 446,
            "y" : 81
          },
          "b" : {
            "x" : 458,
            "y" : 93
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 452,
            "y" : 87
          }
        }
      }
    } ]
  }, {
    "id" : 30613,
    "reactomeId" : 29368,
    "displayName" : "O2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 410,
      "y" : 35
    },
    "minX" : 394,
    "maxX" : 480,
    "minY" : 19,
    "maxY" : 111,
    "prop" : {
      "x" : 394,
      "y" : 20,
      "width" : 33,
      "height" : 30
    },
    "textPosition" : {
      "x" : 398,
      "y" : 24
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 422,
          "y" : 25
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 422,
          "y" : 25
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30610,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 423,
          "y" : 53
        },
        "to" : {
          "x" : 479,
          "y" : 111
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 30635,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 430,
          "y" : 41
        },
        "to" : {
          "x" : 480,
          "y" : 61
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 30614,
    "reactomeId" : 2161759,
    "displayName" : "LXA4",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 641,
      "y" : 112
    },
    "minX" : 551,
    "maxX" : 669,
    "minY" : 96,
    "maxY" : 127,
    "prop" : {
      "x" : 614,
      "y" : 97,
      "width" : 54,
      "height" : 30
    },
    "textPosition" : {
      "x" : 622,
      "y" : 101
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 663,
          "y" : 102
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 663,
          "y" : 102
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30610,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 551,
            "y" : 106
          },
          "b" : {
            "x" : 563,
            "y" : 118
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 557,
            "y" : 112
          }
        }
      }
    } ]
  }, {
    "id" : 30615,
    "reactomeId" : 10042667,
    "displayName" : "ALOX12:Fe2+",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 527,
      "y" : 158
    },
    "minX" : 474,
    "maxX" : 587,
    "minY" : 69,
    "maxY" : 169,
    "prop" : {
      "x" : 474,
      "y" : 147,
      "width" : 107,
      "height" : 22
    },
    "textPosition" : {
      "x" : 482,
      "y" : 148
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 581,
          "y" : 147
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 581,
          "y" : 147
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30610,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 521,
          "y" : 144
        },
        "to" : {
          "x" : 512,
          "y" : 126
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 510,
          "y" : 123
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 510,
          "y" : 123
        }
      }
    }, {
      "edgeId" : 30635,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 525,
          "y" : 144
        },
        "to" : {
          "x" : 517,
          "y" : 77
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 516,
          "y" : 73
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 516,
          "y" : 73
        }
      }
    } ]
  }, {
    "id" : 30617,
    "reactomeId" : 29368,
    "displayName" : "O2",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 356,
      "y" : 417
    },
    "minX" : 300,
    "maxX" : 410,
    "minY" : 401,
    "maxY" : 437,
    "prop" : {
      "x" : 340,
      "y" : 402,
      "width" : 33,
      "height" : 30
    },
    "textPosition" : {
      "x" : 344,
      "y" : 406
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 368,
          "y" : 407
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 368,
          "y" : 407
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30616,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 376,
          "y" : 420
        },
        "to" : {
          "x" : 410,
          "y" : 430
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 30621,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 337,
          "y" : 422
        },
        "to" : {
          "x" : 300,
          "y" : 437
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 30618,
    "reactomeId" : 2142718,
    "displayName" : "15S-HpETE",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 411,
      "y" : 376
    },
    "minX" : 361,
    "maxX" : 463,
    "minY" : 360,
    "maxY" : 430,
    "prop" : {
      "x" : 361,
      "y" : 361,
      "width" : 101,
      "height" : 30
    },
    "textPosition" : {
      "x" : 373,
      "y" : 365
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 457,
          "y" : 366
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 457,
          "y" : 366
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30616,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 410,
          "y" : 394
        },
        "to" : {
          "x" : 410,
          "y" : 430
        }
      } ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 404,
            "y" : 406
          },
          "b" : {
            "x" : 416,
            "y" : 418
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 410,
            "y" : 412
          }
        }
      }
    } ]
  }, {
    "id" : 30619,
    "reactomeId" : 2161856,
    "displayName" : "LXA4/B4",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 411,
      "y" : 530
    },
    "minX" : 374,
    "maxX" : 448,
    "minY" : 486,
    "maxY" : 541,
    "prop" : {
      "x" : 374,
      "y" : 519,
      "width" : 74,
      "height" : 22
    },
    "textPosition" : {
      "x" : 382,
      "y" : 519
    },
    "connectors" : [ {
      "edgeId" : 30616,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 2,
        "shape" : {
          "a" : {
            "x" : 404,
            "y" : 486
          },
          "b" : {
            "x" : 416,
            "y" : 498
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 410,
            "y" : 492
          }
        }
      }
    } ]
  }, {
    "id" : 30620,
    "reactomeId" : 10007584,
    "displayName" : "ALOX5:ALOX5AP:LTC4S",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 193,
      "y" : 469
    },
    "minX" : 128,
    "maxX" : 402,
    "minY" : 310,
    "maxY" : 487,
    "prop" : {
      "x" : 128,
      "y" : 451,
      "width" : 130,
      "height" : 36
    },
    "textPosition" : {
      "x" : 139,
      "y" : 452
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 258,
          "y" : 451
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 258,
          "y" : 451
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30631,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 193,
          "y" : 448
        },
        "to" : {
          "x" : 193,
          "y" : 318
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 193,
          "y" : 314
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 193,
          "y" : 314
        }
      }
    }, {
      "edgeId" : 30616,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 261,
          "y" : 469
        },
        "to" : {
          "x" : 394,
          "y" : 471
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 398,
          "y" : 471
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 398,
          "y" : 471
        }
      }
    }, {
      "edgeId" : 30621,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 261,
          "y" : 476
        },
        "to" : {
          "x" : 283,
          "y" : 480
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 287,
          "y" : 480
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 287,
          "y" : 480
        }
      }
    } ]
  }, {
    "id" : 30622,
    "reactomeId" : 2142738,
    "displayName" : "15R-HETE",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 300,
      "y" : 381
    },
    "minX" : 254,
    "maxX" : 347,
    "minY" : 365,
    "maxY" : 437,
    "prop" : {
      "x" : 254,
      "y" : 366,
      "width" : 92,
      "height" : 30
    },
    "textPosition" : {
      "x" : 266,
      "y" : 370
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 341,
          "y" : 371
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 341,
          "y" : 371
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 30621,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 300,
          "y" : 399
        },
        "to" : {
          "x" : 300,
          "y" : 437
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 30623,
    "reactomeId" : 2161609,
    "displayName" : "15epi-LXA4/B4",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 300,
      "y" : 551
    },
    "minX" : 237,
    "maxX" : 363,
    "minY" : 540,
    "maxY" : 562,
    "prop" : {
      "x" : 237,
      "y" : 540,
      "width" : 126,
      "height" : 22
    },
    "textPosition" : {
      "x" : 252,
      "y" : 540
    },
    "connectors" : [ {
      "edgeId" : 30621,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 30624,
    "reactomeId" : 10042679,
    "displayName" : "LXA4 is oxidised to 15k-LXA4 by HPGD",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 624,
      "y" : 527
    },
    "minX" : 580,
    "maxX" : 684,
    "minY" : 521,
    "maxY" : 533,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 580,
        "y" : 527
      },
      "to" : {
        "x" : 624,
        "y" : 527
      }
    }, {
      "from" : {
        "x" : 624,
        "y" : 527
      },
      "to" : {
        "x" : 684,
        "y" : 527
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 618,
        "y" : 521
      },
      "b" : {
        "x" : 630,
        "y" : 533
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 624,
        "y" : 527
      }
    },
    "inputs" : [ {
      "id" : 30625,
      "points" : [ {
        "x" : 541,
        "y" : 527
      } ]
    }, {
      "id" : 30626,
      "points" : [ {
        "x" : 575,
        "y" : 521
      } ]
    } ],
    "outputs" : [ {
      "id" : 30627,
      "points" : [ {
        "x" : 733,
        "y" : 527
      } ]
    }, {
      "id" : 30628,
      "points" : [ {
        "x" : 694,
        "y" : 562
      } ]
    }, {
      "id" : 30629,
      "points" : [ {
        "x" : 695,
        "y" : 508
      } ]
    } ],
    "catalysts" : [ {
      "id" : 30630,
      "points" : [ {
        "x" : 624,
        "y" : 479
      } ]
    } ]
  }, {
    "id" : 30610,
    "reactomeId" : 10042670,
    "displayName" : "ALOX12 oxidises LTA4 to LXA4",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 504,
      "y" : 112
    },
    "minX" : 479,
    "maxX" : 611,
    "minY" : 106,
    "maxY" : 118,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 479,
        "y" : 111
      },
      "to" : {
        "x" : 504,
        "y" : 112
      }
    }, {
      "from" : {
        "x" : 504,
        "y" : 112
      },
      "to" : {
        "x" : 611,
        "y" : 112
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 604,
        "y" : 116
      },
      "b" : {
        "x" : 611,
        "y" : 112
      },
      "c" : {
        "x" : 604,
        "y" : 108
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 604,
        "y" : 108
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 498,
        "y" : 106
      },
      "b" : {
        "x" : 510,
        "y" : 118
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 504,
        "y" : 112
      }
    },
    "inputs" : [ {
      "id" : 30611,
      "points" : [ {
        "x" : 361,
        "y" : 80
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 30612,
      "points" : [ {
        "x" : 436,
        "y" : 124
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 30613,
      "points" : [ {
        "x" : 423,
        "y" : 53
      } ]
    } ],
    "outputs" : [ {
      "id" : 30614,
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 30615,
      "points" : [ {
        "x" : 521,
        "y" : 144
      } ]
    } ]
  }, {
    "id" : 30631,
    "reactomeId" : 10007780,
    "displayName" : "5S-HpETE is dehydrated to LTA4 by ALOX5",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 193,
      "y" : 302
    },
    "minX" : 142,
    "maxX" : 255,
    "minY" : 296,
    "maxY" : 308,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 142,
        "y" : 302
      },
      "to" : {
        "x" : 193,
        "y" : 302
      }
    }, {
      "from" : {
        "x" : 193,
        "y" : 302
      },
      "to" : {
        "x" : 255,
        "y" : 301
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 187,
        "y" : 296
      },
      "b" : {
        "x" : 199,
        "y" : 308
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 193,
        "y" : 302
      }
    },
    "inputs" : [ {
      "id" : 30632
    } ],
    "outputs" : [ {
      "id" : 30633,
      "points" : [ {
        "x" : 336,
        "y" : 301
      } ]
    }, {
      "id" : 30634,
      "points" : [ {
        "x" : 272,
        "y" : 318
      } ]
    } ],
    "catalysts" : [ {
      "id" : 30620,
      "points" : [ {
        "x" : 193,
        "y" : 448
      } ]
    } ]
  }, {
    "id" : 30616,
    "reactomeId" : 10042727,
    "displayName" : "ALOX5 oxidises 15S-HpETE to LXA4/B4",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 410,
      "y" : 471
    },
    "minX" : 404,
    "maxX" : 416,
    "minY" : 430,
    "maxY" : 513,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 410,
        "y" : 430
      },
      "to" : {
        "x" : 410,
        "y" : 471
      }
    }, {
      "from" : {
        "x" : 410,
        "y" : 471
      },
      "to" : {
        "x" : 410,
        "y" : 513
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 406,
        "y" : 506
      },
      "b" : {
        "x" : 410,
        "y" : 513
      },
      "c" : {
        "x" : 414,
        "y" : 506
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 414,
        "y" : 506
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 404,
        "y" : 465
      },
      "b" : {
        "x" : 416,
        "y" : 477
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 410,
        "y" : 471
      }
    },
    "inputs" : [ {
      "id" : 30617,
      "points" : [ {
        "x" : 376,
        "y" : 420
      } ]
    }, {
      "id" : 30618,
      "points" : [ {
        "x" : 410,
        "y" : 394
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 30619,
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 30620,
      "points" : [ {
        "x" : 261,
        "y" : 469
      } ]
    } ]
  }, {
    "id" : 30635,
    "reactomeId" : 10096454,
    "displayName" : "ALOX12 oxidises LTA4 to LXB4",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 515,
      "y" : 61
    },
    "minX" : 480,
    "maxX" : 610,
    "minY" : 55,
    "maxY" : 67,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 480,
        "y" : 61
      },
      "to" : {
        "x" : 515,
        "y" : 61
      }
    }, {
      "from" : {
        "x" : 515,
        "y" : 61
      },
      "to" : {
        "x" : 610,
        "y" : 62
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 603,
        "y" : 66
      },
      "b" : {
        "x" : 610,
        "y" : 62
      },
      "c" : {
        "x" : 603,
        "y" : 58
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 603,
        "y" : 58
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 509,
        "y" : 55
      },
      "b" : {
        "x" : 521,
        "y" : 67
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 515,
        "y" : 61
      }
    },
    "inputs" : [ {
      "id" : 30612,
      "points" : [ {
        "x" : 424,
        "y" : 113
      } ],
      "stoichiometry" : 2
    }, {
      "id" : 30613,
      "points" : [ {
        "x" : 430,
        "y" : 41
      } ]
    }, {
      "id" : 30611,
      "points" : [ {
        "x" : 361,
        "y" : 72
      } ],
      "stoichiometry" : 2
    } ],
    "outputs" : [ {
      "id" : 30636,
      "stoichiometry" : 2
    } ],
    "catalysts" : [ {
      "id" : 30615,
      "points" : [ {
        "x" : 525,
        "y" : 144
      } ]
    } ]
  }, {
    "id" : 30621,
    "reactomeId" : 10042725,
    "displayName" : "ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 299,
      "y" : 482
    },
    "minX" : 293,
    "maxX" : 305,
    "minY" : 437,
    "maxY" : 534,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 300,
        "y" : 437
      },
      "to" : {
        "x" : 299,
        "y" : 482
      }
    }, {
      "from" : {
        "x" : 299,
        "y" : 482
      },
      "to" : {
        "x" : 299,
        "y" : 534
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 295,
        "y" : 527
      },
      "b" : {
        "x" : 299,
        "y" : 534
      },
      "c" : {
        "x" : 303,
        "y" : 527
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 303,
        "y" : 527
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 293,
        "y" : 476
      },
      "b" : {
        "x" : 305,
        "y" : 488
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 299,
        "y" : 482
      }
    },
    "inputs" : [ {
      "id" : 30617,
      "points" : [ {
        "x" : 337,
        "y" : 422
      } ]
    }, {
      "id" : 30622,
      "points" : [ {
        "x" : 300,
        "y" : 399
      } ]
    } ],
    "outputs" : [ {
      "id" : 30623
    } ],
    "catalysts" : [ {
      "id" : 30620,
      "points" : [ {
        "x" : 261,
        "y" : 476
      } ]
    } ]
  } ],
  "compartments" : [ {
    "id" : 30641,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 511,
      "y" : 96
    },
    "minX" : 281,
    "maxX" : 741,
    "minY" : 0,
    "maxY" : 192,
    "prop" : {
      "x" : 281,
      "y" : 0,
      "width" : 460,
      "height" : 192
    },
    "textPosition" : {
      "x" : 298,
      "y" : 146
    },
    "insets" : {
      "x" : 291,
      "y" : 10,
      "width" : 440,
      "height" : 172
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 30615, 30610, 30612, 30643, 30613, 30611, 30614, 30636, 30635 ]
  }, {
    "id" : 30637,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 558,
      "y" : 420
    },
    "minX" : 0,
    "maxX" : 1117,
    "minY" : 220,
    "maxY" : 620,
    "prop" : {
      "x" : 0,
      "y" : 220,
      "width" : 1117,
      "height" : 400
    },
    "textPosition" : {
      "x" : 25,
      "y" : 548
    },
    "insets" : {
      "x" : 10,
      "y" : 230,
      "width" : 1097,
      "height" : 380
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 30638, 30633, 30631, 30632, 30634, 30622, 30618, 30623, 30616, 30621, 30619, 30625, 30626, 30630, 30624, 30628, 30629, 30646, 30642, 30627, 30617 ]
  }, {
    "id" : 30638,
    "reactomeId" : 13231,
    "displayName" : "nuclear envelope",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 129,
      "y" : 445
    },
    "minX" : 61,
    "maxX" : 198,
    "minY" : 404,
    "maxY" : 486,
    "prop" : {
      "x" : 61,
      "y" : 404,
      "width" : 137,
      "height" : 82
    },
    "textPosition" : {
      "x" : 67,
      "y" : 420
    },
    "insets" : {
      "x" : 71,
      "y" : 414,
      "width" : 117,
      "height" : 62
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 30620 ]
  } ],
  "notes" : [ {
    "id" : 30642,
    "displayName" : "Neutrophil",
    "renderableClass" : "Note",
    "position" : {
      "x" : 60,
      "y" : 544
    },
    "minX" : 25,
    "maxX" : 95,
    "minY" : 529,
    "maxY" : 560,
    "prop" : {
      "x" : 25,
      "y" : 529,
      "width" : 70,
      "height" : 31
    },
    "textPosition" : {
      "x" : 25,
      "y" : 527
    }
  }, {
    "id" : 30643,
    "displayName" : "Platelet",
    "renderableClass" : "Note",
    "position" : {
      "x" : 328,
      "y" : 145
    },
    "minX" : 295,
    "maxX" : 362,
    "minY" : 128,
    "maxY" : 163,
    "prop" : {
      "x" : 295,
      "y" : 128,
      "width" : 67,
      "height" : 35
    },
    "textPosition" : {
      "x" : 300,
      "y" : 135
    }
  } ],
  "links" : [ {
    "id" : 30646,
    "renderableClass" : "EntitySetAndMemberLink",
    "position" : {
      "x" : 467,
      "y" : 528
    },
    "minX" : 454,
    "maxX" : 481,
    "minY" : 522,
    "maxY" : 534,
    "segments" : [ {
      "from" : {
        "x" : 481,
        "y" : 528
      },
      "to" : {
        "x" : 454,
        "y" : 528
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 461,
        "y" : 522
      },
      "b" : {
        "x" : 473,
        "y" : 534
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 467,
        "y" : 528
      }
    },
    "inputs" : [ {
      "id" : 30625
    } ],
    "outputs" : [ {
      "id" : 30619
    } ]
  } ],
  "shadows" : [ ],
  "minX" : 0,
  "maxX" : 1117,
  "minY" : 0,
  "maxY" : 620,
  "disease" : false
}