{
  "dbId" : 10098655,
  "stableId" : "R-MMU-73933",
  "displayName" : "Resolution of Abasic Sites (AP sites)",
  "nodes" : [ {
    "id" : 77313,
    "reactomeId" : 9991872,
    "displayName" : "MBD4:CpG(AP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 509,
      "y" : 718
    },
    "minX" : 437,
    "maxX" : 587,
    "minY" : 691,
    "maxY" : 729,
    "prop" : {
      "x" : 437,
      "y" : 708,
      "width" : 144,
      "height" : 21
    },
    "textPosition" : {
      "x" : 437,
      "y" : 708
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 581,
          "y" : 708
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 581,
          "y" : 708
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77312,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 516,
          "y" : 705
        },
        "to" : {
          "x" : 529,
          "y" : 691
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77314,
    "reactomeId" : 9991868,
    "displayName" : "Mbd4",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 701,
      "y" : 719
    },
    "minX" : 662,
    "maxX" : 743,
    "minY" : 690,
    "maxY" : 730,
    "prop" : {
      "x" : 665,
      "y" : 708,
      "width" : 72,
      "height" : 22
    },
    "textPosition" : {
      "x" : 680,
      "y" : 708
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 737,
          "y" : 708
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 737,
          "y" : 708
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77312,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 686,
          "y" : 705
        },
        "to" : {
          "x" : 662,
          "y" : 690
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 678,
          "y" : 705
        },
        "b" : {
          "x" : 686,
          "y" : 705
        },
        "c" : {
          "x" : 682,
          "y" : 698
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 682,
          "y" : 698
        }
      }
    } ]
  }, {
    "id" : 77317,
    "reactomeId" : 113541,
    "displayName" : "PPi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2173,
      "y" : 545
    },
    "minX" : 2133,
    "maxX" : 2201,
    "minY" : 509,
    "maxY" : 598,
    "prop" : {
      "x" : 2146,
      "y" : 532,
      "width" : 54,
      "height" : 26
    },
    "textPosition" : {
      "x" : 2159,
      "y" : 534
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2195,
          "y" : 537
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2195,
          "y" : 537
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77315,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2158,
          "y" : 529
        },
        "to" : {
          "x" : 2133,
          "y" : 509
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2150,
          "y" : 528
        },
        "b" : {
          "x" : 2158,
          "y" : 529
        },
        "c" : {
          "x" : 2155,
          "y" : 522
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2155,
          "y" : 522
        }
      }
    }, {
      "edgeId" : 77333,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2176,
          "y" : 561
        },
        "to" : {
          "x" : 2188,
          "y" : 598
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2182,
          "y" : 566
        },
        "b" : {
          "x" : 2176,
          "y" : 561
        },
        "c" : {
          "x" : 2174,
          "y" : 569
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2174,
          "y" : 569
        }
      }
    } ]
  }, {
    "id" : 77316,
    "reactomeId" : 30555,
    "displayName" : "dNTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2099,
      "y" : 542
    },
    "minX" : 2076,
    "maxX" : 2136,
    "minY" : 509,
    "maxY" : 599,
    "prop" : {
      "x" : 2077,
      "y" : 529,
      "width" : 45,
      "height" : 27
    },
    "textPosition" : {
      "x" : 2079,
      "y" : 532
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2117,
          "y" : 534
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2117,
          "y" : 534
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77315,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2089,
          "y" : 526
        },
        "to" : {
          "x" : 2076,
          "y" : 509
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77333,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2107,
          "y" : 559
        },
        "to" : {
          "x" : 2136,
          "y" : 599
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77319,
    "reactomeId" : 10057542,
    "displayName" : "NEIL1,NEIL2",
    "schemaClass" : "CandidateSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 445,
      "y" : 1042
    },
    "minX" : 418,
    "maxX" : 505,
    "minY" : 989,
    "maxY" : 1063,
    "prop" : {
      "x" : 418,
      "y" : 1022,
      "width" : 54,
      "height" : 41
    },
    "textPosition" : {
      "x" : 422,
      "y" : 1025
    },
    "connectors" : [ {
      "edgeId" : 77318,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 468,
          "y" : 1016
        },
        "to" : {
          "x" : 505,
          "y" : 989
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77320,
    "reactomeId" : 10057544,
    "displayName" : "NEIL1,NEIL2:AP-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 676,
      "y" : 1037
    },
    "minX" : 606,
    "maxX" : 780,
    "minY" : 988,
    "maxY" : 1057,
    "prop" : {
      "x" : 630,
      "y" : 1018,
      "width" : 93,
      "height" : 39
    },
    "textPosition" : {
      "x" : 634,
      "y" : 1022
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 723,
          "y" : 1018
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 723,
          "y" : 1018
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77318,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 648,
          "y" : 1015
        },
        "to" : {
          "x" : 606,
          "y" : 988
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 640,
          "y" : 1015
        },
        "b" : {
          "x" : 648,
          "y" : 1015
        },
        "c" : {
          "x" : 644,
          "y" : 1008
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 644,
          "y" : 1008
        }
      }
    }, {
      "edgeId" : 77321,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77321,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 726,
          "y" : 1024
        },
        "to" : {
          "x" : 753,
          "y" : 1017
        }
      }, {
        "from" : {
          "x" : 753,
          "y" : 1017
        },
        "to" : {
          "x" : 773,
          "y" : 1029
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 776,
          "y" : 1032
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 776,
          "y" : 1032
        }
      }
    } ]
  }, {
    "id" : 77322,
    "reactomeId" : 10057565,
    "displayName" : "NEIL1,NEIL2:SSB(3'Pi-5'dRP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 936,
      "y" : 966
    },
    "minX" : 825,
    "maxX" : 1377,
    "minY" : 759,
    "maxY" : 979,
    "prop" : {
      "x" : 825,
      "y" : 953,
      "width" : 223,
      "height" : 26
    },
    "textPosition" : {
      "x" : 845,
      "y" : 944
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1048,
          "y" : 953
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1048,
          "y" : 953
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77321,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77323,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 963,
          "y" : 950
        },
        "to" : {
          "x" : 1377,
          "y" : 759
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77324,
    "reactomeId" : 10057567,
    "displayName" : "NEIL1:NEIL2:POLB:SSB(3'Pi-5'dRP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1375,
      "y" : 600
    },
    "minX" : 1316,
    "maxX" : 1484,
    "minY" : 567,
    "maxY" : 624,
    "prop" : {
      "x" : 1316,
      "y" : 576,
      "width" : 119,
      "height" : 48
    },
    "textPosition" : {
      "x" : 1316,
      "y" : 575
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1435,
          "y" : 576
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1435,
          "y" : 576
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77323,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77337,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77337,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1438,
          "y" : 577
        },
        "to" : {
          "x" : 1464,
          "y" : 567
        }
      }, {
        "from" : {
          "x" : 1464,
          "y" : 567
        },
        "to" : {
          "x" : 1478,
          "y" : 589
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1480,
          "y" : 593
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1480,
          "y" : 593
        }
      }
    } ]
  }, {
    "id" : 77327,
    "reactomeId" : 113518,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1913,
      "y" : 644
    },
    "minX" : 1892,
    "maxX" : 1936,
    "minY" : 597,
    "maxY" : 659,
    "prop" : {
      "x" : 1892,
      "y" : 629,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 1896,
      "y" : 633
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1930,
          "y" : 634
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1930,
          "y" : 634
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77325,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1915,
          "y" : 626
        },
        "to" : {
          "x" : 1921,
          "y" : 597
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 77326,
    "reactomeId" : 10057556,
    "displayName" : "NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB(3'Pi)-gap-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1829,
      "y" : 606
    },
    "minX" : 1763,
    "maxX" : 1941,
    "minY" : 561,
    "maxY" : 632,
    "prop" : {
      "x" : 1763,
      "y" : 581,
      "width" : 132,
      "height" : 51
    },
    "textPosition" : {
      "x" : 1769,
      "y" : 569
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1895,
          "y" : 581
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1895,
          "y" : 581
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77325,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1898,
          "y" : 599
        },
        "to" : {
          "x" : 1921,
          "y" : 597
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77325,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1882,
          "y" : 578
        },
        "to" : {
          "x" : 1923,
          "y" : 561
        }
      }, {
        "from" : {
          "x" : 1923,
          "y" : 561
        },
        "to" : {
          "x" : 1935,
          "y" : 582
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1937,
          "y" : 586
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1937,
          "y" : 586
        }
      }
    }, {
      "edgeId" : 77330,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77329,
    "reactomeId" : 113550,
    "displayName" : "Pi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1982,
      "y" : 645
    },
    "minX" : 1964,
    "maxX" : 2001,
    "minY" : 596,
    "maxY" : 657,
    "prop" : {
      "x" : 1964,
      "y" : 633,
      "width" : 36,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1972,
      "y" : 634
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1995,
          "y" : 638
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1995,
          "y" : 638
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77325,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1977,
          "y" : 630
        },
        "to" : {
          "x" : 1965,
          "y" : 596
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1971,
          "y" : 625
        },
        "b" : {
          "x" : 1977,
          "y" : 630
        },
        "c" : {
          "x" : 1978,
          "y" : 622
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1978,
          "y" : 622
        }
      }
    } ]
  }, {
    "id" : 77328,
    "reactomeId" : 10057558,
    "displayName" : "NEIL1,NEIL2:POLB:LIG3:XRCC1:PNKP:SSB-gap-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2056,
      "y" : 603
    },
    "minX" : 1965,
    "maxX" : 2151,
    "minY" : 572,
    "maxY" : 635,
    "prop" : {
      "x" : 1997,
      "y" : 578,
      "width" : 118,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1998,
      "y" : 565
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2115,
          "y" : 578
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2115,
          "y" : 578
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77325,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1994,
          "y" : 598
        },
        "to" : {
          "x" : 1965,
          "y" : 596
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1987,
          "y" : 602
        },
        "b" : {
          "x" : 1994,
          "y" : 598
        },
        "c" : {
          "x" : 1987,
          "y" : 594
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1987,
          "y" : 594
        }
      }
    }, {
      "edgeId" : 77333,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2118,
          "y" : 600
        },
        "to" : {
          "x" : 2136,
          "y" : 599
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77333,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2114,
          "y" : 631
        },
        "to" : {
          "x" : 2131,
          "y" : 635
        }
      }, {
        "from" : {
          "x" : 2131,
          "y" : 635
        },
        "to" : {
          "x" : 2144,
          "y" : 614
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2147,
          "y" : 610
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2147,
          "y" : 610
        }
      }
    } ]
  }, {
    "id" : 77331,
    "reactomeId" : 10057550,
    "displayName" : "NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1622,
      "y" : 603
    },
    "minX" : 1507,
    "maxX" : 1725,
    "minY" : 574,
    "maxY" : 627,
    "prop" : {
      "x" : 1563,
      "y" : 580,
      "width" : 119,
      "height" : 47
    },
    "textPosition" : {
      "x" : 1563,
      "y" : 578
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1682,
          "y" : 580
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1682,
          "y" : 580
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77330,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1685,
          "y" : 599
        },
        "to" : {
          "x" : 1725,
          "y" : 597
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77337,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1560,
          "y" : 603
        },
        "to" : {
          "x" : 1507,
          "y" : 603
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1553,
          "y" : 607
        },
        "b" : {
          "x" : 1560,
          "y" : 603
        },
        "c" : {
          "x" : 1553,
          "y" : 599
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1553,
          "y" : 599
        }
      }
    } ]
  }, {
    "id" : 77332,
    "reactomeId" : 10057554,
    "displayName" : "PNKP",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1711,
      "y" : 636
    },
    "minX" : 1690,
    "maxX" : 1739,
    "minY" : 597,
    "maxY" : 647,
    "prop" : {
      "x" : 1690,
      "y" : 626,
      "width" : 43,
      "height" : 21
    },
    "textPosition" : {
      "x" : 1691,
      "y" : 626
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1733,
          "y" : 626
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1733,
          "y" : 626
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77330,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1714,
          "y" : 623
        },
        "to" : {
          "x" : 1725,
          "y" : 597
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77334,
    "reactomeId" : 10057574,
    "displayName" : "NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:SSB-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2282,
      "y" : 602
    },
    "minX" : 2188,
    "maxX" : 2388,
    "minY" : 571,
    "maxY" : 627,
    "prop" : {
      "x" : 2223,
      "y" : 577,
      "width" : 119,
      "height" : 50
    },
    "textPosition" : {
      "x" : 2228,
      "y" : 564
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2342,
          "y" : 577
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2342,
          "y" : 577
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77333,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2220,
          "y" : 599
        },
        "to" : {
          "x" : 2188,
          "y" : 598
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2213,
          "y" : 603
        },
        "b" : {
          "x" : 2220,
          "y" : 599
        },
        "c" : {
          "x" : 2213,
          "y" : 595
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2213,
          "y" : 595
        }
      }
    }, {
      "edgeId" : 77335,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77335,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2345,
          "y" : 585
        },
        "to" : {
          "x" : 2368,
          "y" : 578
        }
      }, {
        "from" : {
          "x" : 2368,
          "y" : 578
        },
        "to" : {
          "x" : 2381,
          "y" : 592
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2384,
          "y" : 595
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2384,
          "y" : 595
        }
      }
    } ]
  }, {
    "id" : 77336,
    "reactomeId" : 10057579,
    "displayName" : "NEIL1,NEIL2:PNKP:POLB:LIG3:XRCC1:dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2487,
      "y" : 602
    },
    "minX" : 2424,
    "maxX" : 2556,
    "minY" : 570,
    "maxY" : 628,
    "prop" : {
      "x" : 2424,
      "y" : 576,
      "width" : 126,
      "height" : 52
    },
    "textPosition" : {
      "x" : 2427,
      "y" : 579
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2550,
          "y" : 576
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2550,
          "y" : 576
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77335,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77339,
    "reactomeId" : 9992112,
    "displayName" : "APEX1:SSB(5'-ddRP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1137,
      "y" : 709
    },
    "minX" : 1096,
    "maxX" : 1217,
    "minY" : 678,
    "maxY" : 771,
    "prop" : {
      "x" : 1096,
      "y" : 684,
      "width" : 82,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1099,
      "y" : 685
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1178,
          "y" : 684
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1178,
          "y" : 684
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77338,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77340,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1169,
          "y" : 737
        },
        "to" : {
          "x" : 1217,
          "y" : 771
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77341,
    "reactomeId" : 9992114,
    "displayName" : "POLB:APEX1:SSB(5'ddRP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1217,
      "y" : 931
    },
    "minX" : 1175,
    "maxX" : 1321,
    "minY" : 889,
    "maxY" : 956,
    "prop" : {
      "x" : 1175,
      "y" : 906,
      "width" : 84,
      "height" : 50
    },
    "textPosition" : {
      "x" : 1179,
      "y" : 893
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1259,
          "y" : 906
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1259,
          "y" : 906
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77340,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77342,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1262,
          "y" : 929
        },
        "to" : {
          "x" : 1293,
          "y" : 929
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77342,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1262,
          "y" : 907
        },
        "to" : {
          "x" : 1291,
          "y" : 889
        }
      }, {
        "from" : {
          "x" : 1291,
          "y" : 889
        },
        "to" : {
          "x" : 1315,
          "y" : 917
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1317,
          "y" : 920
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1317,
          "y" : 920
        }
      }
    } ]
  }, {
    "id" : 77343,
    "reactomeId" : 30555,
    "displayName" : "dNTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1271,
      "y" : 976
    },
    "minX" : 1249,
    "maxX" : 1295,
    "minY" : 929,
    "maxY" : 990,
    "prop" : {
      "x" : 1249,
      "y" : 963,
      "width" : 45,
      "height" : 27
    },
    "textPosition" : {
      "x" : 1251,
      "y" : 966
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1289,
          "y" : 968
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1289,
          "y" : 968
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77342,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1277,
          "y" : 960
        },
        "to" : {
          "x" : 1293,
          "y" : 929
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77345,
    "reactomeId" : 113541,
    "displayName" : "PPi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1370,
      "y" : 975
    },
    "minX" : 1343,
    "maxX" : 1398,
    "minY" : 928,
    "maxY" : 988,
    "prop" : {
      "x" : 1343,
      "y" : 962,
      "width" : 54,
      "height" : 26
    },
    "textPosition" : {
      "x" : 1356,
      "y" : 964
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1392,
          "y" : 967
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1392,
          "y" : 967
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77342,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1364,
          "y" : 959
        },
        "to" : {
          "x" : 1351,
          "y" : 928
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1358,
          "y" : 954
        },
        "b" : {
          "x" : 1364,
          "y" : 959
        },
        "c" : {
          "x" : 1365,
          "y" : 951
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1365,
          "y" : 951
        }
      }
    } ]
  }, {
    "id" : 77344,
    "reactomeId" : 9992081,
    "displayName" : "POLB:APEX1:SSB(3'dNMP-displaced 5'ddRP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1468,
      "y" : 929
    },
    "minX" : 1351,
    "maxX" : 1578,
    "minY" : 898,
    "maxY" : 1111,
    "prop" : {
      "x" : 1401,
      "y" : 904,
      "width" : 135,
      "height" : 51
    },
    "textPosition" : {
      "x" : 1405,
      "y" : 906
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1536,
          "y" : 904
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1536,
          "y" : 904
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77342,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1398,
          "y" : 928
        },
        "to" : {
          "x" : 1351,
          "y" : 928
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1391,
          "y" : 932
        },
        "b" : {
          "x" : 1398,
          "y" : 928
        },
        "c" : {
          "x" : 1391,
          "y" : 924
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1391,
          "y" : 924
        }
      }
    }, {
      "edgeId" : 77346,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1539,
          "y" : 929
        },
        "to" : {
          "x" : 1578,
          "y" : 930
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77369,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1468,
          "y" : 958
        },
        "to" : {
          "x" : 1471,
          "y" : 1111
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77347,
    "reactomeId" : 10057640,
    "displayName" : "PARP1,PARP2 dimers",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1582,
      "y" : 823
    },
    "minX" : 1554,
    "maxX" : 1771,
    "minY" : 776,
    "maxY" : 930,
    "prop" : {
      "x" : 1554,
      "y" : 799,
      "width" : 56,
      "height" : 48
    },
    "textPosition" : {
      "x" : 1556,
      "y" : 798
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1610,
          "y" : 799
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1610,
          "y" : 799
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77380,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1613,
          "y" : 816
        },
        "to" : {
          "x" : 1771,
          "y" : 776
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1619,
          "y" : 810
        },
        "b" : {
          "x" : 1613,
          "y" : 816
        },
        "c" : {
          "x" : 1621,
          "y" : 818
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1621,
          "y" : 818
        }
      }
    }, {
      "edgeId" : 77346,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1581,
          "y" : 850
        },
        "to" : {
          "x" : 1578,
          "y" : 930
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77349,
    "reactomeId" : 10057642,
    "displayName" : "PARP1,PARP2:FEN1:POLB:SSB(3'dNMP-displaced 5'ddRP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1759,
      "y" : 934
    },
    "minX" : 1633,
    "maxX" : 1869,
    "minY" : 882,
    "maxY" : 967,
    "prop" : {
      "x" : 1697,
      "y" : 901,
      "width" : 124,
      "height" : 66
    },
    "textPosition" : {
      "x" : 1696,
      "y" : 904
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1821,
          "y" : 901
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1821,
          "y" : 901
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77346,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1694,
          "y" : 933
        },
        "to" : {
          "x" : 1633,
          "y" : 932
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1687,
          "y" : 937
        },
        "b" : {
          "x" : 1694,
          "y" : 933
        },
        "c" : {
          "x" : 1687,
          "y" : 929
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1687,
          "y" : 929
        }
      }
    }, {
      "edgeId" : 77352,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1824,
          "y" : 931
        },
        "to" : {
          "x" : 1851,
          "y" : 930
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77352,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1799,
          "y" : 898
        },
        "to" : {
          "x" : 1823,
          "y" : 882
        }
      }, {
        "from" : {
          "x" : 1823,
          "y" : 882
        },
        "to" : {
          "x" : 1862,
          "y" : 919
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1865,
          "y" : 922
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1865,
          "y" : 922
        }
      }
    } ]
  }, {
    "id" : 77348,
    "reactomeId" : 9985605,
    "displayName" : "FEN1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1537,
      "y" : 1000
    },
    "minX" : 1471,
    "maxX" : 1578,
    "minY" : 930,
    "maxY" : 1111,
    "prop" : {
      "x" : 1516,
      "y" : 989,
      "width" : 42,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1517,
      "y" : 989
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1558,
          "y" : 989
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1558,
          "y" : 989
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77346,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1543,
          "y" : 986
        },
        "to" : {
          "x" : 1578,
          "y" : 930
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77369,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1530,
          "y" : 1014
        },
        "to" : {
          "x" : 1471,
          "y" : 1111
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77351,
    "reactomeId" : 10057646,
    "displayName" : "PARG",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1923,
      "y" : 827
    },
    "minX" : 1609,
    "maxX" : 1950,
    "minY" : 783,
    "maxY" : 922,
    "prop" : {
      "x" : 1903,
      "y" : 816,
      "width" : 41,
      "height" : 22
    },
    "textPosition" : {
      "x" : 1903,
      "y" : 816
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1944,
          "y" : 816
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1944,
          "y" : 816
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77380,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1923,
          "y" : 813
        },
        "to" : {
          "x" : 1923,
          "y" : 791
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1923,
          "y" : 787
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1923,
          "y" : 787
        }
      }
    }, {
      "edgeId" : 77346,
      "type" : "ACTIVATOR",
      "segments" : [ {
        "from" : {
          "x" : 1900,
          "y" : 826
        },
        "to" : {
          "x" : 1642,
          "y" : 824
        }
      }, {
        "from" : {
          "x" : 1642,
          "y" : 824
        },
        "to" : {
          "x" : 1611,
          "y" : 922
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1609,
          "y" : 914
        },
        "b" : {
          "x" : 1611,
          "y" : 922
        },
        "c" : {
          "x" : 1617,
          "y" : 917
        },
        "type" : "ARROW",
        "empty" : true,
        "centre" : {
          "x" : 1617,
          "y" : 917
        }
      }
    } ]
  }, {
    "id" : 77350,
    "reactomeId" : 9992038,
    "displayName" : "APEX1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1690,
      "y" : 849
    },
    "minX" : 1633,
    "maxX" : 1732,
    "minY" : 831,
    "maxY" : 932,
    "prop" : {
      "x" : 1654,
      "y" : 837,
      "width" : 72,
      "height" : 25
    },
    "textPosition" : {
      "x" : 1666,
      "y" : 839
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1726,
          "y" : 837
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1726,
          "y" : 837
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77346,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1681,
          "y" : 865
        },
        "to" : {
          "x" : 1633,
          "y" : 932
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1680,
          "y" : 873
        },
        "b" : {
          "x" : 1681,
          "y" : 865
        },
        "c" : {
          "x" : 1674,
          "y" : 868
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1674,
          "y" : 868
        }
      }
    } ]
  }, {
    "id" : 77353,
    "reactomeId" : 30555,
    "displayName" : "dNTP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1832,
      "y" : 996
    },
    "minX" : 1779,
    "maxX" : 1856,
    "minY" : 930,
    "maxY" : 1110,
    "prop" : {
      "x" : 1810,
      "y" : 983,
      "width" : 45,
      "height" : 27
    },
    "textPosition" : {
      "x" : 1812,
      "y" : 986
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1850,
          "y" : 988
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1850,
          "y" : 988
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77352,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1835,
          "y" : 980
        },
        "to" : {
          "x" : 1851,
          "y" : 930
        }
      } ],
      "stoichiometry" : {
        "value" : 10,
        "shape" : {
          "a" : {
            "x" : 1837,
            "y" : 949
          },
          "b" : {
            "x" : 1849,
            "y" : 961
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1843,
            "y" : 955
          }
        }
      }
    }, {
      "edgeId" : 77373,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1825,
          "y" : 1013
        },
        "to" : {
          "x" : 1779,
          "y" : 1110
        }
      } ],
      "stoichiometry" : {
        "value" : 10,
        "shape" : {
          "a" : {
            "x" : 1796,
            "y" : 1055
          },
          "b" : {
            "x" : 1808,
            "y" : 1067
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1802,
            "y" : 1061
          }
        }
      }
    } ]
  }, {
    "id" : 77355,
    "reactomeId" : 113541,
    "displayName" : "PPi",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1922,
      "y" : 996
    },
    "minX" : 1870,
    "maxX" : 1950,
    "minY" : 930,
    "maxY" : 1106,
    "prop" : {
      "x" : 1895,
      "y" : 983,
      "width" : 54,
      "height" : 26
    },
    "textPosition" : {
      "x" : 1908,
      "y" : 985
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1944,
          "y" : 988
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1944,
          "y" : 988
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77352,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1918,
          "y" : 980
        },
        "to" : {
          "x" : 1904,
          "y" : 930
        }
      } ],
      "stoichiometry" : {
        "value" : 10,
        "shape" : {
          "a" : {
            "x" : 1905,
            "y" : 949
          },
          "b" : {
            "x" : 1917,
            "y" : 961
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1911,
            "y" : 955
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1912,
          "y" : 974
        },
        "b" : {
          "x" : 1918,
          "y" : 980
        },
        "c" : {
          "x" : 1920,
          "y" : 972
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1920,
          "y" : 972
        }
      }
    }, {
      "edgeId" : 77373,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1915,
          "y" : 1012
        },
        "to" : {
          "x" : 1870,
          "y" : 1106
        }
      } ],
      "stoichiometry" : {
        "value" : 10,
        "shape" : {
          "a" : {
            "x" : 1886,
            "y" : 1053
          },
          "b" : {
            "x" : 1898,
            "y" : 1065
          },
          "type" : "BOX",
          "empty" : true,
          "centre" : {
            "x" : 1892,
            "y" : 1059
          }
        }
      },
      "endShape" : {
        "a" : {
          "x" : 1916,
          "y" : 1020
        },
        "b" : {
          "x" : 1915,
          "y" : 1012
        },
        "c" : {
          "x" : 1908,
          "y" : 1017
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1908,
          "y" : 1017
        }
      }
    } ]
  }, {
    "id" : 77354,
    "reactomeId" : 10057651,
    "displayName" : "PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2027,
      "y" : 932
    },
    "minX" : 1904,
    "maxX" : 2162,
    "minY" : 884,
    "maxY" : 964,
    "prop" : {
      "x" : 1940,
      "y" : 901,
      "width" : 175,
      "height" : 63
    },
    "textPosition" : {
      "x" : 1944,
      "y" : 901
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2115,
          "y" : 901
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2115,
          "y" : 901
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77352,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1937,
          "y" : 930
        },
        "to" : {
          "x" : 1904,
          "y" : 930
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1930,
          "y" : 934
        },
        "b" : {
          "x" : 1937,
          "y" : 930
        },
        "c" : {
          "x" : 1930,
          "y" : 926
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1930,
          "y" : 926
        }
      }
    }, {
      "edgeId" : 77356,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2118,
          "y" : 928
        },
        "to" : {
          "x" : 2140,
          "y" : 927
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77356,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2100,
          "y" : 898
        },
        "to" : {
          "x" : 2139,
          "y" : 884
        }
      }, {
        "from" : {
          "x" : 2139,
          "y" : 884
        },
        "to" : {
          "x" : 2156,
          "y" : 913
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2158,
          "y" : 917
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2158,
          "y" : 917
        }
      }
    } ]
  }, {
    "id" : 77357,
    "reactomeId" : 427523,
    "displayName" : "NAD+",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2127,
      "y" : 992
    },
    "minX" : 2100,
    "maxX" : 2155,
    "minY" : 927,
    "maxY" : 1006,
    "prop" : {
      "x" : 2100,
      "y" : 978,
      "width" : 54,
      "height" : 28
    },
    "textPosition" : {
      "x" : 2105,
      "y" : 981
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2149,
          "y" : 983
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2149,
          "y" : 983
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77356,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2129,
          "y" : 975
        },
        "to" : {
          "x" : 2140,
          "y" : 927
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77359,
    "reactomeId" : 10057684,
    "displayName" : "PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2298,
      "y" : 926
    },
    "minX" : 2186,
    "maxX" : 2357,
    "minY" : 867,
    "maxY" : 979,
    "prop" : {
      "x" : 2246,
      "y" : 873,
      "width" : 105,
      "height" : 106
    },
    "textPosition" : {
      "x" : 2247,
      "y" : 874
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2351,
          "y" : 873
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2351,
          "y" : 873
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77356,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2243,
          "y" : 927
        },
        "to" : {
          "x" : 2186,
          "y" : 929
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2236,
          "y" : 931
        },
        "b" : {
          "x" : 2243,
          "y" : 927
        },
        "c" : {
          "x" : 2236,
          "y" : 923
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2236,
          "y" : 923
        }
      }
    }, {
      "edgeId" : 77360,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77358,
    "reactomeId" : 427497,
    "displayName" : "NAM",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2204,
      "y" : 991
    },
    "minX" : 2180,
    "maxX" : 2229,
    "minY" : 929,
    "maxY" : 1007,
    "prop" : {
      "x" : 2180,
      "y" : 976,
      "width" : 48,
      "height" : 31
    },
    "textPosition" : {
      "x" : 2186,
      "y" : 981
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2223,
          "y" : 981
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2223,
          "y" : 981
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77356,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2199,
          "y" : 973
        },
        "to" : {
          "x" : 2186,
          "y" : 929
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2193,
          "y" : 967
        },
        "b" : {
          "x" : 2199,
          "y" : 973
        },
        "c" : {
          "x" : 2201,
          "y" : 965
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2201,
          "y" : 965
        }
      }
    } ]
  }, {
    "id" : 77361,
    "reactomeId" : 10057682,
    "displayName" : "PAR-PARP1,PAR-PARP2 dimers",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2405,
      "y" : 834
    },
    "minX" : 2116,
    "maxX" : 2452,
    "minY" : 776,
    "maxY" : 919,
    "prop" : {
      "x" : 2365,
      "y" : 809,
      "width" : 81,
      "height" : 51
    },
    "textPosition" : {
      "x" : 2365,
      "y" : 811
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2446,
          "y" : 809
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2446,
          "y" : 809
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77380,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2362,
          "y" : 825
        },
        "to" : {
          "x" : 2116,
          "y" : 776
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77360,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2401,
          "y" : 863
        },
        "to" : {
          "x" : 2394,
          "y" : 919
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2404,
          "y" : 870
        },
        "b" : {
          "x" : 2401,
          "y" : 863
        },
        "c" : {
          "x" : 2396,
          "y" : 869
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2396,
          "y" : 869
        }
      }
    } ]
  }, {
    "id" : 77362,
    "reactomeId" : 10057689,
    "displayName" : "FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2478,
      "y" : 921
    },
    "minX" : 2394,
    "maxX" : 2537,
    "minY" : 872,
    "maxY" : 964,
    "prop" : {
      "x" : 2426,
      "y" : 878,
      "width" : 105,
      "height" : 86
    },
    "textPosition" : {
      "x" : 2427,
      "y" : 887
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2531,
          "y" : 878
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2531,
          "y" : 878
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77360,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2423,
          "y" : 919
        },
        "to" : {
          "x" : 2394,
          "y" : 919
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2416,
          "y" : 923
        },
        "b" : {
          "x" : 2423,
          "y" : 919
        },
        "c" : {
          "x" : 2416,
          "y" : 915
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2416,
          "y" : 915
        }
      }
    } ]
  }, {
    "id" : 77365,
    "reactomeId" : 9985612,
    "displayName" : "LIG1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 2613,
      "y" : 1062
    },
    "minX" : 2460,
    "maxX" : 2671,
    "minY" : 1029,
    "maxY" : 1183,
    "prop" : {
      "x" : 2590,
      "y" : 1051,
      "width" : 46,
      "height" : 23
    },
    "textPosition" : {
      "x" : 2596,
      "y" : 1052
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2636,
          "y" : 1051
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2636,
          "y" : 1051
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77363,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2633,
          "y" : 1048
        },
        "to" : {
          "x" : 2671,
          "y" : 1029
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77375,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2603,
          "y" : 1077
        },
        "to" : {
          "x" : 2517,
          "y" : 1181
        }
      }, {
        "from" : {
          "x" : 2517,
          "y" : 1181
        },
        "to" : {
          "x" : 2460,
          "y" : 1183
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77364,
    "reactomeId" : 10057693,
    "displayName" : "POLB:SSB(3'poly-dNMP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2677,
      "y" : 978
    },
    "minX" : 2605,
    "maxX" : 2756,
    "minY" : 950,
    "maxY" : 1029,
    "prop" : {
      "x" : 2605,
      "y" : 956,
      "width" : 145,
      "height" : 45
    },
    "textPosition" : {
      "x" : 2621,
      "y" : 966
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2750,
          "y" : 956
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2750,
          "y" : 956
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77363,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2674,
          "y" : 1004
        },
        "to" : {
          "x" : 2671,
          "y" : 1029
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77366,
    "reactomeId" : 10057695,
    "displayName" : "LIG1:POLB:SSB(3'poly-dNMP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2677,
      "y" : 1121
    },
    "minX" : 2634,
    "maxX" : 2726,
    "minY" : 1084,
    "maxY" : 1198,
    "prop" : {
      "x" : 2634,
      "y" : 1090,
      "width" : 86,
      "height" : 63
    },
    "textPosition" : {
      "x" : 2638,
      "y" : 1090
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2720,
          "y" : 1090
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2720,
          "y" : 1090
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77363,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77367,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77367,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2658,
          "y" : 1156
        },
        "to" : {
          "x" : 2642,
          "y" : 1181
        }
      }, {
        "from" : {
          "x" : 2642,
          "y" : 1181
        },
        "to" : {
          "x" : 2660,
          "y" : 1192
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2663,
          "y" : 1194
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2663,
          "y" : 1194
        }
      }
    } ]
  }, {
    "id" : 77368,
    "reactomeId" : 10057699,
    "displayName" : "LIG1:POLB:dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2676,
      "y" : 1266
    },
    "minX" : 2636,
    "maxX" : 2723,
    "minY" : 1239,
    "maxY" : 1287,
    "prop" : {
      "x" : 2636,
      "y" : 1245,
      "width" : 81,
      "height" : 42
    },
    "textPosition" : {
      "x" : 2640,
      "y" : 1252
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2717,
          "y" : 1245
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2717,
          "y" : 1245
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77367,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77371,
    "reactomeId" : 9992083,
    "displayName" : "APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1645,
      "y" : 1114
    },
    "minX" : 1533,
    "maxX" : 1827,
    "minY" : 1076,
    "maxY" : 1147,
    "prop" : {
      "x" : 1573,
      "y" : 1082,
      "width" : 144,
      "height" : 65
    },
    "textPosition" : {
      "x" : 1578,
      "y" : 1070
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1717,
          "y" : 1082
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1717,
          "y" : 1082
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77369,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1570,
          "y" : 1111
        },
        "to" : {
          "x" : 1533,
          "y" : 1110
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1563,
          "y" : 1115
        },
        "b" : {
          "x" : 1570,
          "y" : 1111
        },
        "c" : {
          "x" : 1563,
          "y" : 1107
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1563,
          "y" : 1107
        }
      }
    }, {
      "edgeId" : 77373,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1720,
          "y" : 1111
        },
        "to" : {
          "x" : 1779,
          "y" : 1110
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77373,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1720,
          "y" : 1134
        },
        "to" : {
          "x" : 1763,
          "y" : 1147
        }
      }, {
        "from" : {
          "x" : 1763,
          "y" : 1147
        },
        "to" : {
          "x" : 1819,
          "y" : 1115
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1823,
          "y" : 1113
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1823,
          "y" : 1113
        }
      }
    } ]
  }, {
    "id" : 77370,
    "reactomeId" : 9992073,
    "displayName" : "PCNA:POLD,POLE:RPA:RFC",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1350,
      "y" : 1112
    },
    "minX" : 1301,
    "maxX" : 1471,
    "minY" : 1089,
    "maxY" : 1130,
    "prop" : {
      "x" : 1301,
      "y" : 1095,
      "width" : 98,
      "height" : 35
    },
    "textPosition" : {
      "x" : 1303,
      "y" : 1095
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1399,
          "y" : 1095
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1399,
          "y" : 1095
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77369,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1402,
          "y" : 1111
        },
        "to" : {
          "x" : 1471,
          "y" : 1111
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77372,
    "reactomeId" : 9988583,
    "displayName" : "POLB",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1569,
      "y" : 1052
    },
    "minX" : 1533,
    "maxX" : 1602,
    "minY" : 1031,
    "maxY" : 1110,
    "prop" : {
      "x" : 1543,
      "y" : 1037,
      "width" : 53,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1550,
      "y" : 1042
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1596,
          "y" : 1037
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1596,
          "y" : 1037
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77369,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1559,
          "y" : 1071
        },
        "to" : {
          "x" : 1533,
          "y" : 1110
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1558,
          "y" : 1079
        },
        "b" : {
          "x" : 1559,
          "y" : 1071
        },
        "c" : {
          "x" : 1552,
          "y" : 1075
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1552,
          "y" : 1075
        }
      }
    } ]
  }, {
    "id" : 77374,
    "reactomeId" : 9992077,
    "displayName" : "APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2019,
      "y" : 1101
    },
    "minX" : 1870,
    "maxX" : 2122,
    "minY" : 1068,
    "maxY" : 1128,
    "prop" : {
      "x" : 1922,
      "y" : 1074,
      "width" : 194,
      "height" : 54
    },
    "textPosition" : {
      "x" : 1924,
      "y" : 1065
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2116,
          "y" : 1074
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2116,
          "y" : 1074
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77373,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1919,
          "y" : 1104
        },
        "to" : {
          "x" : 1870,
          "y" : 1106
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1912,
          "y" : 1108
        },
        "b" : {
          "x" : 1919,
          "y" : 1104
        },
        "c" : {
          "x" : 1912,
          "y" : 1100
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1912,
          "y" : 1100
        }
      }
    } ]
  }, {
    "id" : 77377,
    "reactomeId" : 9992094,
    "displayName" : "LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2465,
      "y" : 1243
    },
    "minX" : 2371,
    "maxX" : 2565,
    "minY" : 1209,
    "maxY" : 1317,
    "prop" : {
      "x" : 2371,
      "y" : 1215,
      "width" : 188,
      "height" : 56
    },
    "textPosition" : {
      "x" : 2379,
      "y" : 1222
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2559,
          "y" : 1215
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2559,
          "y" : 1215
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77378,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77378,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2436,
          "y" : 1274
        },
        "to" : {
          "x" : 2413,
          "y" : 1294
        }
      }, {
        "from" : {
          "x" : 2413,
          "y" : 1294
        },
        "to" : {
          "x" : 2455,
          "y" : 1312
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2459,
          "y" : 1313
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2459,
          "y" : 1313
        }
      }
    }, {
      "edgeId" : 77375,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77376,
    "reactomeId" : 9992092,
    "displayName" : "APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2459,
      "y" : 1117
    },
    "minX" : 2379,
    "maxX" : 2545,
    "minY" : 1084,
    "maxY" : 1183,
    "prop" : {
      "x" : 2379,
      "y" : 1090,
      "width" : 160,
      "height" : 54
    },
    "textPosition" : {
      "x" : 2379,
      "y" : 1095
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2539,
          "y" : 1090
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2539,
          "y" : 1090
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77375,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2459,
          "y" : 1147
        },
        "to" : {
          "x" : 2460,
          "y" : 1183
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77379,
    "reactomeId" : 10057704,
    "displayName" : "LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2474,
      "y" : 1372
    },
    "minX" : 2379,
    "maxX" : 2576,
    "minY" : 1348,
    "maxY" : 1391,
    "prop" : {
      "x" : 2379,
      "y" : 1354,
      "width" : 191,
      "height" : 37
    },
    "textPosition" : {
      "x" : 2380,
      "y" : 1356
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2570,
          "y" : 1354
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2570,
          "y" : 1354
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77378,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77381,
    "reactomeId" : 113518,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 2185,
      "y" : 739
    },
    "minX" : 2116,
    "maxX" : 2208,
    "minY" : 723,
    "maxY" : 776,
    "prop" : {
      "x" : 2164,
      "y" : 724,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 2168,
      "y" : 728
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2202,
          "y" : 729
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2202,
          "y" : 729
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77380,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2161,
          "y" : 750
        },
        "to" : {
          "x" : 2116,
          "y" : 776
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 77382,
    "reactomeId" : 5651834,
    "displayName" : "ADP-D-ribose",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1705,
      "y" : 730
    },
    "minX" : 1653,
    "maxX" : 1771,
    "minY" : 714,
    "maxY" : 776,
    "prop" : {
      "x" : 1653,
      "y" : 715,
      "width" : 104,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1660,
      "y" : 720
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1752,
          "y" : 720
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1752,
          "y" : 720
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77380,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1727,
          "y" : 749
        },
        "to" : {
          "x" : 1771,
          "y" : 776
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1735,
          "y" : 749
        },
        "b" : {
          "x" : 1727,
          "y" : 749
        },
        "c" : {
          "x" : 1731,
          "y" : 756
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1731,
          "y" : 756
        }
      }
    } ]
  }, {
    "id" : 77385,
    "reactomeId" : 113521,
    "displayName" : "H2O",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 391,
      "y" : 106
    },
    "minX" : 370,
    "maxX" : 437,
    "minY" : 90,
    "maxY" : 134,
    "prop" : {
      "x" : 370,
      "y" : 91,
      "width" : 43,
      "height" : 30
    },
    "textPosition" : {
      "x" : 374,
      "y" : 95
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 408,
          "y" : 96
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 408,
          "y" : 96
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77383,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 416,
          "y" : 119
        },
        "to" : {
          "x" : 437,
          "y" : 134
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ],
    "trivial" : true
  }, {
    "id" : 77384,
    "reactomeId" : 8952909,
    "displayName" : "poly(ADP-ribose)",
    "schemaClass" : "Polymer",
    "renderableClass" : "Entity",
    "position" : {
      "x" : 421,
      "y" : 170
    },
    "minX" : 367,
    "maxX" : 509,
    "minY" : 134,
    "maxY" : 181,
    "prop" : {
      "x" : 367,
      "y" : 159,
      "width" : 108,
      "height" : 22
    },
    "textPosition" : {
      "x" : 387,
      "y" : 153
    },
    "connectors" : [ {
      "edgeId" : 77383,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 425,
          "y" : 156
        },
        "to" : {
          "x" : 437,
          "y" : 134
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77383,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 447,
          "y" : 156
        },
        "to" : {
          "x" : 509,
          "y" : 134
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 452,
          "y" : 150
        },
        "b" : {
          "x" : 447,
          "y" : 156
        },
        "c" : {
          "x" : 455,
          "y" : 157
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 455,
          "y" : 157
        }
      }
    } ]
  }, {
    "id" : 77387,
    "reactomeId" : 10083816,
    "displayName" : "ADPRHL2",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 464,
      "y" : 93
    },
    "minX" : 432,
    "maxX" : 502,
    "minY" : 76,
    "maxY" : 126,
    "prop" : {
      "x" : 432,
      "y" : 82,
      "width" : 64,
      "height" : 22
    },
    "textPosition" : {
      "x" : 432,
      "y" : 82
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 496,
          "y" : 82
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 496,
          "y" : 82
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77383,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 464,
          "y" : 107
        },
        "to" : {
          "x" : 464,
          "y" : 118
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 465,
          "y" : 122
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 465,
          "y" : 122
        }
      }
    } ]
  }, {
    "id" : 77386,
    "reactomeId" : 8952905,
    "displayName" : "ADP-ribose",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 588,
      "y" : 134
    },
    "minX" : 509,
    "maxX" : 631,
    "minY" : 118,
    "maxY" : 149,
    "prop" : {
      "x" : 546,
      "y" : 119,
      "width" : 84,
      "height" : 30
    },
    "textPosition" : {
      "x" : 550,
      "y" : 123
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 625,
          "y" : 124
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 625,
          "y" : 124
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77383,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 543,
          "y" : 134
        },
        "to" : {
          "x" : 509,
          "y" : 134
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 536,
          "y" : 138
        },
        "b" : {
          "x" : 543,
          "y" : 134
        },
        "c" : {
          "x" : 536,
          "y" : 130
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 536,
          "y" : 130
        }
      }
    } ]
  }, {
    "id" : 77389,
    "reactomeId" : 10098897,
    "displayName" : "Base-Excision Repair, AP Site Formation",
    "schemaClass" : "Pathway",
    "renderableClass" : "EncapsulatedNode",
    "position" : {
      "x" : 150,
      "y" : 665
    },
    "minX" : 75,
    "maxX" : 226,
    "minY" : 621,
    "maxY" : 709,
    "prop" : {
      "x" : 75,
      "y" : 621,
      "width" : 151,
      "height" : 88
    },
    "textPosition" : {
      "x" : 74,
      "y" : 643
    },
    "connectors" : [ ]
  }, {
    "id" : 77275,
    "reactomeId" : 9992038,
    "displayName" : "APEX1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 298,
      "y" : 658
    },
    "minX" : 262,
    "maxX" : 530,
    "minY" : 393,
    "maxY" : 917,
    "prop" : {
      "x" : 262,
      "y" : 646,
      "width" : 72,
      "height" : 25
    },
    "textPosition" : {
      "x" : 274,
      "y" : 648
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 334,
          "y" : 646
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 334,
          "y" : 646
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77312,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 337,
          "y" : 663
        },
        "to" : {
          "x" : 529,
          "y" : 691
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77274,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 301,
          "y" : 643
        },
        "to" : {
          "x" : 378,
          "y" : 395
        }
      }, {
        "from" : {
          "x" : 378,
          "y" : 395
        },
        "to" : {
          "x" : 481,
          "y" : 393
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77279,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 304,
          "y" : 643
        },
        "to" : {
          "x" : 408,
          "y" : 456
        }
      }, {
        "from" : {
          "x" : 408,
          "y" : 456
        },
        "to" : {
          "x" : 500,
          "y" : 457
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77282,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 312,
          "y" : 643
        },
        "to" : {
          "x" : 435,
          "y" : 542
        }
      }, {
        "from" : {
          "x" : 435,
          "y" : 542
        },
        "to" : {
          "x" : 530,
          "y" : 544
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77285,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 337,
          "y" : 651
        },
        "to" : {
          "x" : 508,
          "y" : 619
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77288,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 299,
          "y" : 674
        },
        "to" : {
          "x" : 338,
          "y" : 911
        }
      }, {
        "from" : {
          "x" : 338,
          "y" : 911
        },
        "to" : {
          "x" : 440,
          "y" : 917
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77291,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 309,
          "y" : 674
        },
        "to" : {
          "x" : 391,
          "y" : 762
        }
      }, {
        "from" : {
          "x" : 391,
          "y" : 762
        },
        "to" : {
          "x" : 466,
          "y" : 764
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77294,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 302,
          "y" : 674
        },
        "to" : {
          "x" : 367,
          "y" : 834
        }
      }, {
        "from" : {
          "x" : 367,
          "y" : 834
        },
        "to" : {
          "x" : 433,
          "y" : 834
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77277,
    "reactomeId" : 9991791,
    "displayName" : "UNG-1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 631,
      "y" : 347
    },
    "minX" : 602,
    "maxX" : 662,
    "minY" : 330,
    "maxY" : 380,
    "prop" : {
      "x" : 606,
      "y" : 336,
      "width" : 50,
      "height" : 22
    },
    "textPosition" : {
      "x" : 607,
      "y" : 336
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 656,
          "y" : 336
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 656,
          "y" : 336
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77274,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 621,
          "y" : 361
        },
        "to" : {
          "x" : 602,
          "y" : 380
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 619,
          "y" : 369
        },
        "b" : {
          "x" : 621,
          "y" : 361
        },
        "c" : {
          "x" : 613,
          "y" : 363
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 613,
          "y" : 363
        }
      }
    } ]
  }, {
    "id" : 77276,
    "reactomeId" : 9991797,
    "displayName" : "UNG-1:AP-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 449,
      "y" : 355
    },
    "minX" : 399,
    "maxX" : 506,
    "minY" : 331,
    "maxY" : 393,
    "prop" : {
      "x" : 399,
      "y" : 337,
      "width" : 101,
      "height" : 36
    },
    "textPosition" : {
      "x" : 414,
      "y" : 338
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 500,
          "y" : 337
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 500,
          "y" : 337
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77274,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 464,
          "y" : 376
        },
        "to" : {
          "x" : 481,
          "y" : 393
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77278,
    "reactomeId" : 9992040,
    "displayName" : "APEX1:AP-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 880,
      "y" : 593
    },
    "minX" : 598,
    "maxX" : 995,
    "minY" : 380,
    "maxY" : 926,
    "prop" : {
      "x" : 820,
      "y" : 581,
      "width" : 121,
      "height" : 24
    },
    "textPosition" : {
      "x" : 824,
      "y" : 584
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 941,
          "y" : 581
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 941,
          "y" : 581
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77312,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 853,
          "y" : 608
        },
        "to" : {
          "x" : 662,
          "y" : 690
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 848,
          "y" : 614
        },
        "b" : {
          "x" : 853,
          "y" : 608
        },
        "c" : {
          "x" : 845,
          "y" : 607
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 845,
          "y" : 607
        }
      }
    }, {
      "edgeId" : 77274,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 872,
          "y" : 578
        },
        "to" : {
          "x" : 783,
          "y" : 439
        }
      }, {
        "from" : {
          "x" : 783,
          "y" : 439
        },
        "to" : {
          "x" : 602,
          "y" : 380
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 865,
          "y" : 574
        },
        "b" : {
          "x" : 872,
          "y" : 578
        },
        "c" : {
          "x" : 872,
          "y" : 570
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 872,
          "y" : 570
        }
      }
    }, {
      "edgeId" : 77279,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 866,
          "y" : 578
        },
        "to" : {
          "x" : 722,
          "y" : 457
        }
      }, {
        "from" : {
          "x" : 722,
          "y" : 457
        },
        "to" : {
          "x" : 598,
          "y" : 456
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 858,
          "y" : 577
        },
        "b" : {
          "x" : 866,
          "y" : 578
        },
        "c" : {
          "x" : 863,
          "y" : 570
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 863,
          "y" : 570
        }
      }
    }, {
      "edgeId" : 77282,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 842,
          "y" : 578
        },
        "to" : {
          "x" : 719,
          "y" : 541
        }
      }, {
        "from" : {
          "x" : 719,
          "y" : 541
        },
        "to" : {
          "x" : 627,
          "y" : 544
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 834,
          "y" : 580
        },
        "b" : {
          "x" : 842,
          "y" : 578
        },
        "c" : {
          "x" : 837,
          "y" : 572
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 837,
          "y" : 572
        }
      }
    }, {
      "edgeId" : 77285,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 817,
          "y" : 601
        },
        "to" : {
          "x" : 662,
          "y" : 624
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 811,
          "y" : 606
        },
        "b" : {
          "x" : 817,
          "y" : 601
        },
        "c" : {
          "x" : 810,
          "y" : 598
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 810,
          "y" : 598
        }
      }
    }, {
      "edgeId" : 77288,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 877,
          "y" : 608
        },
        "to" : {
          "x" : 806,
          "y" : 926
        }
      }, {
        "from" : {
          "x" : 806,
          "y" : 926
        },
        "to" : {
          "x" : 663,
          "y" : 926
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 879,
          "y" : 616
        },
        "b" : {
          "x" : 877,
          "y" : 608
        },
        "c" : {
          "x" : 872,
          "y" : 614
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 872,
          "y" : 614
        }
      }
    }, {
      "edgeId" : 77291,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 868,
          "y" : 608
        },
        "to" : {
          "x" : 722,
          "y" : 753
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 866,
          "y" : 616
        },
        "b" : {
          "x" : 868,
          "y" : 608
        },
        "c" : {
          "x" : 860,
          "y" : 610
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 860,
          "y" : 610
        }
      }
    }, {
      "edgeId" : 77294,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 876,
          "y" : 608
        },
        "to" : {
          "x" : 802,
          "y" : 832
        }
      }, {
        "from" : {
          "x" : 802,
          "y" : 832
        },
        "to" : {
          "x" : 680,
          "y" : 839
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 878,
          "y" : 616
        },
        "b" : {
          "x" : 876,
          "y" : 608
        },
        "c" : {
          "x" : 870,
          "y" : 613
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 870,
          "y" : 613
        }
      }
    }, {
      "edgeId" : 77297,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77297,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 908,
          "y" : 578
        },
        "to" : {
          "x" : 967,
          "y" : 556
        }
      }, {
        "from" : {
          "x" : 967,
          "y" : 556
        },
        "to" : {
          "x" : 988,
          "y" : 579
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 991,
          "y" : 582
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 991,
          "y" : 582
        }
      }
    } ]
  }, {
    "id" : 77281,
    "reactomeId" : 9991778,
    "displayName" : "Tdg",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 616,
      "y" : 425
    },
    "minX" : 590,
    "maxX" : 648,
    "minY" : 408,
    "maxY" : 456,
    "prop" : {
      "x" : 590,
      "y" : 414,
      "width" : 52,
      "height" : 23
    },
    "textPosition" : {
      "x" : 600,
      "y" : 415
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 642,
          "y" : 414
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 642,
          "y" : 414
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77279,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 609,
          "y" : 440
        },
        "to" : {
          "x" : 598,
          "y" : 456
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 608,
          "y" : 448
        },
        "b" : {
          "x" : 609,
          "y" : 440
        },
        "c" : {
          "x" : 602,
          "y" : 443
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 602,
          "y" : 443
        }
      }
    } ]
  }, {
    "id" : 77280,
    "reactomeId" : 9991811,
    "displayName" : "TDG:AP-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 481,
      "y" : 425
    },
    "minX" : 427,
    "maxX" : 542,
    "minY" : 406,
    "maxY" : 457,
    "prop" : {
      "x" : 427,
      "y" : 412,
      "width" : 109,
      "height" : 26
    },
    "textPosition" : {
      "x" : 432,
      "y" : 417
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 536,
          "y" : 412
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 536,
          "y" : 412
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77279,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 488,
          "y" : 441
        },
        "to" : {
          "x" : 500,
          "y" : 457
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77283,
    "reactomeId" : 9992046,
    "displayName" : "SMUG1:AP-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 504,
      "y" : 500
    },
    "minX" : 444,
    "maxX" : 570,
    "minY" : 483,
    "maxY" : 544,
    "prop" : {
      "x" : 444,
      "y" : 489,
      "width" : 120,
      "height" : 22
    },
    "textPosition" : {
      "x" : 445,
      "y" : 490
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 564,
          "y" : 489
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 564,
          "y" : 489
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77282,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 510,
          "y" : 514
        },
        "to" : {
          "x" : 530,
          "y" : 544
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77284,
    "reactomeId" : 9991782,
    "displayName" : "SMUG1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 649,
      "y" : 505
    },
    "minX" : 620,
    "maxX" : 685,
    "minY" : 486,
    "maxY" : 544,
    "prop" : {
      "x" : 620,
      "y" : 492,
      "width" : 59,
      "height" : 26
    },
    "textPosition" : {
      "x" : 623,
      "y" : 494
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 679,
          "y" : 492
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 679,
          "y" : 492
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77282,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 641,
          "y" : 521
        },
        "to" : {
          "x" : 627,
          "y" : 544
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 641,
          "y" : 529
        },
        "b" : {
          "x" : 641,
          "y" : 521
        },
        "c" : {
          "x" : 634,
          "y" : 525
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 634,
          "y" : 525
        }
      }
    } ]
  }, {
    "id" : 77287,
    "reactomeId" : 9991786,
    "displayName" : "NTHL1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 678,
      "y" : 573
    },
    "minX" : 653,
    "maxX" : 710,
    "minY" : 555,
    "maxY" : 624,
    "prop" : {
      "x" : 653,
      "y" : 561,
      "width" : 51,
      "height" : 25
    },
    "textPosition" : {
      "x" : 655,
      "y" : 563
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 704,
          "y" : 561
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 704,
          "y" : 561
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77285,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 674,
          "y" : 589
        },
        "to" : {
          "x" : 662,
          "y" : 624
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 676,
          "y" : 597
        },
        "b" : {
          "x" : 674,
          "y" : 589
        },
        "c" : {
          "x" : 668,
          "y" : 594
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 668,
          "y" : 594
        }
      }
    } ]
  }, {
    "id" : 77286,
    "reactomeId" : 9991838,
    "displayName" : "NTHL1:AP-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 491,
      "y" : 578
    },
    "minX" : 433,
    "maxX" : 556,
    "minY" : 559,
    "maxY" : 619,
    "prop" : {
      "x" : 433,
      "y" : 565,
      "width" : 117,
      "height" : 26
    },
    "textPosition" : {
      "x" : 435,
      "y" : 570
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 550,
          "y" : 565
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 550,
          "y" : 565
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77285,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 496,
          "y" : 594
        },
        "to" : {
          "x" : 508,
          "y" : 619
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77289,
    "reactomeId" : 9991903,
    "displayName" : "OGG1:AP-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 422,
      "y" : 955
    },
    "minX" : 363,
    "maxX" : 505,
    "minY" : 917,
    "maxY" : 989,
    "prop" : {
      "x" : 363,
      "y" : 942,
      "width" : 118,
      "height" : 27
    },
    "textPosition" : {
      "x" : 368,
      "y" : 948
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 481,
          "y" : 942
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 481,
          "y" : 942
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77318,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 454,
          "y" : 972
        },
        "to" : {
          "x" : 505,
          "y" : 989
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77288,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 428,
          "y" : 939
        },
        "to" : {
          "x" : 440,
          "y" : 917
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77290,
    "reactomeId" : 9991893,
    "displayName" : "OGG1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 691,
      "y" : 963
    },
    "minX" : 606,
    "maxX" : 728,
    "minY" : 926,
    "maxY" : 988,
    "prop" : {
      "x" : 660,
      "y" : 953,
      "width" : 62,
      "height" : 21
    },
    "textPosition" : {
      "x" : 669,
      "y" : 953
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 722,
          "y" : 953
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 722,
          "y" : 953
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77318,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 657,
          "y" : 972
        },
        "to" : {
          "x" : 606,
          "y" : 988
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 652,
          "y" : 978
        },
        "b" : {
          "x" : 657,
          "y" : 972
        },
        "c" : {
          "x" : 649,
          "y" : 970
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 649,
          "y" : 970
        }
      }
    }, {
      "edgeId" : 77288,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 683,
          "y" : 950
        },
        "to" : {
          "x" : 663,
          "y" : 926
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 675,
          "y" : 947
        },
        "b" : {
          "x" : 683,
          "y" : 950
        },
        "c" : {
          "x" : 682,
          "y" : 942
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 682,
          "y" : 942
        }
      }
    } ]
  }, {
    "id" : 77293,
    "reactomeId" : 9991920,
    "displayName" : "MUTYH",
    "schemaClass" : "DefinedSet",
    "renderableClass" : "EntitySet",
    "position" : {
      "x" : 747,
      "y" : 797
    },
    "minX" : 722,
    "maxX" : 773,
    "minY" : 753,
    "maxY" : 808,
    "prop" : {
      "x" : 722,
      "y" : 786,
      "width" : 51,
      "height" : 22
    },
    "textPosition" : {
      "x" : 722,
      "y" : 786
    },
    "connectors" : [ {
      "edgeId" : 77291,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 740,
          "y" : 780
        },
        "to" : {
          "x" : 722,
          "y" : 753
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 733,
          "y" : 776
        },
        "b" : {
          "x" : 740,
          "y" : 780
        },
        "c" : {
          "x" : 739,
          "y" : 772
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 739,
          "y" : 772
        }
      }
    } ]
  }, {
    "id" : 77292,
    "reactomeId" : 9991924,
    "displayName" : "MUTYH:AP-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 446,
      "y" : 801
    },
    "minX" : 383,
    "maxX" : 515,
    "minY" : 764,
    "maxY" : 814,
    "prop" : {
      "x" : 383,
      "y" : 789,
      "width" : 126,
      "height" : 25
    },
    "textPosition" : {
      "x" : 388,
      "y" : 793
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 509,
          "y" : 789
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 509,
          "y" : 789
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77291,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 452,
          "y" : 786
        },
        "to" : {
          "x" : 466,
          "y" : 764
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77295,
    "reactomeId" : 9991933,
    "displayName" : "MPG:AP-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 410,
      "y" : 879
    },
    "minX" : 353,
    "maxX" : 473,
    "minY" : 834,
    "maxY" : 893,
    "prop" : {
      "x" : 353,
      "y" : 866,
      "width" : 114,
      "height" : 27
    },
    "textPosition" : {
      "x" : 360,
      "y" : 872
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 467,
          "y" : 866
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 467,
          "y" : 866
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77294,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 416,
          "y" : 863
        },
        "to" : {
          "x" : 433,
          "y" : 834
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77296,
    "reactomeId" : 9991897,
    "displayName" : "Mpg",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 722,
      "y" : 888
    },
    "minX" : 680,
    "maxX" : 760,
    "minY" : 839,
    "maxY" : 901,
    "prop" : {
      "x" : 690,
      "y" : 876,
      "width" : 64,
      "height" : 25
    },
    "textPosition" : {
      "x" : 705,
      "y" : 878
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 754,
          "y" : 876
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 754,
          "y" : 876
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77294,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 711,
          "y" : 873
        },
        "to" : {
          "x" : 680,
          "y" : 839
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 703,
          "y" : 871
        },
        "b" : {
          "x" : 711,
          "y" : 873
        },
        "c" : {
          "x" : 709,
          "y" : 865
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 709,
          "y" : 865
        }
      }
    } ]
  }, {
    "id" : 77298,
    "reactomeId" : 9992062,
    "displayName" : "APEX1:SSB(AP->5'-dRP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1134,
      "y" : 594
    },
    "minX" : 1028,
    "maxX" : 1270,
    "minY" : 576,
    "maxY" : 606,
    "prop" : {
      "x" : 1028,
      "y" : 582,
      "width" : 212,
      "height" : 24
    },
    "textPosition" : {
      "x" : 1034,
      "y" : 585
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1240,
          "y" : 582
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1240,
          "y" : 582
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77338,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77297,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77299,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1243,
          "y" : 600
        },
        "to" : {
          "x" : 1270,
          "y" : 602
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77301,
    "reactomeId" : 9992067,
    "displayName" : "POLB:APEX1:SSB(AP->5'-dRP)-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1345,
      "y" : 506
    },
    "minX" : 1229,
    "maxX" : 1504,
    "minY" : 444,
    "maxY" : 520,
    "prop" : {
      "x" : 1229,
      "y" : 492,
      "width" : 232,
      "height" : 28
    },
    "textPosition" : {
      "x" : 1248,
      "y" : 485
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1461,
          "y" : 492
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1461,
          "y" : 492
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77299,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77302,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77302,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 1372,
          "y" : 489
        },
        "to" : {
          "x" : 1465,
          "y" : 444
        }
      }, {
        "from" : {
          "x" : 1465,
          "y" : 444
        },
        "to" : {
          "x" : 1497,
          "y" : 475
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 1500,
          "y" : 478
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1500,
          "y" : 478
        }
      }
    } ]
  }, {
    "id" : 77300,
    "reactomeId" : 9988583,
    "displayName" : "POLB",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1294,
      "y" : 671
    },
    "minX" : 1217,
    "maxX" : 1377,
    "minY" : 602,
    "maxY" : 771,
    "prop" : {
      "x" : 1268,
      "y" : 656,
      "width" : 53,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1275,
      "y" : 661
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1321,
          "y" : 656
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1321,
          "y" : 656
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77323,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1308,
          "y" : 690
        },
        "to" : {
          "x" : 1377,
          "y" : 759
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77340,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1282,
          "y" : 690
        },
        "to" : {
          "x" : 1217,
          "y" : 771
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77299,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1288,
          "y" : 653
        },
        "to" : {
          "x" : 1270,
          "y" : 602
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77303,
    "reactomeId" : 30977,
    "displayName" : "SUGP",
    "schemaClass" : "SimpleEntity",
    "renderableClass" : "Chemical",
    "position" : {
      "x" : 1589,
      "y" : 543
    },
    "minX" : 1507,
    "maxX" : 1622,
    "minY" : 488,
    "maxY" : 603,
    "prop" : {
      "x" : 1557,
      "y" : 528,
      "width" : 64,
      "height" : 31
    },
    "textPosition" : {
      "x" : 1568,
      "y" : 533
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1616,
          "y" : 533
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1616,
          "y" : 533
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77337,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1567,
          "y" : 562
        },
        "to" : {
          "x" : 1507,
          "y" : 603
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1564,
          "y" : 569
        },
        "b" : {
          "x" : 1567,
          "y" : 562
        },
        "c" : {
          "x" : 1559,
          "y" : 563
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1559,
          "y" : 563
        }
      }
    }, {
      "edgeId" : 77302,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1574,
          "y" : 525
        },
        "to" : {
          "x" : 1537,
          "y" : 488
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1566,
          "y" : 523
        },
        "b" : {
          "x" : 1574,
          "y" : 525
        },
        "c" : {
          "x" : 1572,
          "y" : 517
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1572,
          "y" : 517
        }
      }
    } ]
  }, {
    "id" : 77305,
    "reactomeId" : 9992038,
    "displayName" : "APEX1",
    "schemaClass" : "EntityWithAccessionedSequence",
    "renderableClass" : "Protein",
    "position" : {
      "x" : 1591,
      "y" : 422
    },
    "minX" : 1537,
    "maxX" : 1633,
    "minY" : 404,
    "maxY" : 488,
    "prop" : {
      "x" : 1555,
      "y" : 410,
      "width" : 72,
      "height" : 25
    },
    "textPosition" : {
      "x" : 1567,
      "y" : 412
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1627,
          "y" : 410
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1627,
          "y" : 410
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77302,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1580,
          "y" : 438
        },
        "to" : {
          "x" : 1537,
          "y" : 488
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1579,
          "y" : 446
        },
        "b" : {
          "x" : 1580,
          "y" : 438
        },
        "c" : {
          "x" : 1572,
          "y" : 441
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1572,
          "y" : 441
        }
      }
    } ]
  }, {
    "id" : 77304,
    "reactomeId" : 9988608,
    "displayName" : "POLB:SSB-gap-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1682,
      "y" : 500
    },
    "minX" : 1537,
    "maxX" : 1806,
    "minY" : 482,
    "maxY" : 513,
    "prop" : {
      "x" : 1604,
      "y" : 488,
      "width" : 156,
      "height" : 25
    },
    "textPosition" : {
      "x" : 1612,
      "y" : 492
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1760,
          "y" : 488
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1760,
          "y" : 488
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77302,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 1601,
          "y" : 493
        },
        "to" : {
          "x" : 1537,
          "y" : 488
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 1594,
          "y" : 496
        },
        "b" : {
          "x" : 1601,
          "y" : 493
        },
        "c" : {
          "x" : 1594,
          "y" : 488
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 1594,
          "y" : 488
        }
      }
    }, {
      "edgeId" : 77306,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1763,
          "y" : 502
        },
        "to" : {
          "x" : 1806,
          "y" : 504
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77307,
    "reactomeId" : 9988595,
    "displayName" : "LIG3:XRCC1",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1829,
      "y" : 437
    },
    "minX" : 1725,
    "maxX" : 1883,
    "minY" : 421,
    "maxY" : 597,
    "prop" : {
      "x" : 1781,
      "y" : 427,
      "width" : 96,
      "height" : 20
    },
    "textPosition" : {
      "x" : 1790,
      "y" : 426
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 1877,
          "y" : 427
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 1877,
          "y" : 427
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77330,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1822,
          "y" : 450
        },
        "to" : {
          "x" : 1725,
          "y" : 597
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77306,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 1825,
          "y" : 450
        },
        "to" : {
          "x" : 1806,
          "y" : 504
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77308,
    "reactomeId" : 9988610,
    "displayName" : "LIG3:XRCC1:POLB:SSB-gap-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 1976,
      "y" : 505
    },
    "minX" : 1914,
    "maxX" : 2095,
    "minY" : 470,
    "maxY" : 525,
    "prop" : {
      "x" : 1914,
      "y" : 486,
      "width" : 125,
      "height" : 39
    },
    "textPosition" : {
      "x" : 1918,
      "y" : 490
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2039,
          "y" : 486
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2039,
          "y" : 486
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77315,
      "type" : "INPUT",
      "segments" : [ {
        "from" : {
          "x" : 2042,
          "y" : 507
        },
        "to" : {
          "x" : 2076,
          "y" : 509
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77315,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2028,
          "y" : 483
        },
        "to" : {
          "x" : 2071,
          "y" : 470
        }
      }, {
        "from" : {
          "x" : 2071,
          "y" : 470
        },
        "to" : {
          "x" : 2089,
          "y" : 497
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2091,
          "y" : 500
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2091,
          "y" : 500
        }
      }
    }, {
      "edgeId" : 77306,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77311,
    "reactomeId" : 9988601,
    "displayName" : "LIG3:XRCC1:POLB:dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2453,
      "y" : 501
    },
    "minX" : 2389,
    "maxX" : 2523,
    "minY" : 476,
    "maxY" : 520,
    "prop" : {
      "x" : 2389,
      "y" : 482,
      "width" : 128,
      "height" : 38
    },
    "textPosition" : {
      "x" : 2395,
      "y" : 485
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2517,
          "y" : 482
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2517,
          "y" : 482
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77309,
      "type" : "OUTPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    } ]
  }, {
    "id" : 77310,
    "reactomeId" : 9988597,
    "displayName" : "LIG3:XRCC1:POLB:SSB-dsDNA",
    "schemaClass" : "Complex",
    "renderableClass" : "Complex",
    "position" : {
      "x" : 2240,
      "y" : 503
    },
    "minX" : 2133,
    "maxX" : 2345,
    "minY" : 451,
    "maxY" : 522,
    "prop" : {
      "x" : 2181,
      "y" : 484,
      "width" : 118,
      "height" : 38
    },
    "textPosition" : {
      "x" : 2182,
      "y" : 487
    },
    "bgColor" : {
      "r" : 204,
      "g" : 255,
      "b" : 255
    },
    "interactorsSummary" : {
      "type" : "TR",
      "shape" : {
        "c" : {
          "x" : 2299,
          "y" : 484
        },
        "r" : 6,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2299,
          "y" : 484
        }
      }
    },
    "connectors" : [ {
      "edgeId" : 77315,
      "type" : "OUTPUT",
      "segments" : [ {
        "from" : {
          "x" : 2178,
          "y" : 506
        },
        "to" : {
          "x" : 2133,
          "y" : 509
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "a" : {
          "x" : 2171,
          "y" : 510
        },
        "b" : {
          "x" : 2178,
          "y" : 506
        },
        "c" : {
          "x" : 2171,
          "y" : 502
        },
        "type" : "ARROW",
        "centre" : {
          "x" : 2171,
          "y" : 502
        }
      }
    }, {
      "edgeId" : 77309,
      "type" : "INPUT",
      "segments" : [ ],
      "stoichiometry" : {
        "value" : 1
      }
    }, {
      "edgeId" : 77309,
      "type" : "CATALYST",
      "segments" : [ {
        "from" : {
          "x" : 2271,
          "y" : 481
        },
        "to" : {
          "x" : 2325,
          "y" : 451
        }
      }, {
        "from" : {
          "x" : 2325,
          "y" : 451
        },
        "to" : {
          "x" : 2340,
          "y" : 484
        }
      } ],
      "stoichiometry" : {
        "value" : 1
      },
      "endShape" : {
        "c" : {
          "x" : 2341,
          "y" : 488
        },
        "r" : 4,
        "type" : "CIRCLE",
        "empty" : true,
        "centre" : {
          "x" : 2341,
          "y" : 488
        }
      }
    } ]
  } ],
  "edges" : [ {
    "id" : 77312,
    "reactomeId" : 9992052,
    "displayName" : "Displacement of MBD4 glycosylase by APEX1 at the AP site",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 603,
      "y" : 688
    },
    "minX" : 529,
    "maxX" : 662,
    "minY" : 682,
    "maxY" : 694,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 529,
        "y" : 691
      },
      "to" : {
        "x" : 603,
        "y" : 688
      }
    }, {
      "from" : {
        "x" : 603,
        "y" : 688
      },
      "to" : {
        "x" : 662,
        "y" : 690
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 597,
        "y" : 682
      },
      "b" : {
        "x" : 609,
        "y" : 694
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 603,
        "y" : 688
      }
    },
    "inputs" : [ {
      "id" : 77313,
      "points" : [ {
        "x" : 516,
        "y" : 705
      } ]
    }, {
      "id" : 77275,
      "points" : [ {
        "x" : 337,
        "y" : 663
      } ]
    } ],
    "outputs" : [ {
      "id" : 77314,
      "points" : [ {
        "x" : 686,
        "y" : 705
      } ]
    }, {
      "id" : 77278,
      "points" : [ {
        "x" : 853,
        "y" : 608
      } ]
    } ]
  }, {
    "id" : 77315,
    "reactomeId" : 9988613,
    "displayName" : "Resynthesis of excised residue by POLB",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2098,
      "y" : 510
    },
    "minX" : 2076,
    "maxX" : 2133,
    "minY" : 504,
    "maxY" : 516,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2076,
        "y" : 509
      },
      "to" : {
        "x" : 2098,
        "y" : 510
      }
    }, {
      "from" : {
        "x" : 2098,
        "y" : 510
      },
      "to" : {
        "x" : 2133,
        "y" : 509
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2092,
        "y" : 504
      },
      "b" : {
        "x" : 2104,
        "y" : 516
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2098,
        "y" : 510
      }
    },
    "inputs" : [ {
      "id" : 77308,
      "points" : [ {
        "x" : 2042,
        "y" : 507
      } ]
    }, {
      "id" : 77316,
      "points" : [ {
        "x" : 2089,
        "y" : 526
      } ]
    } ],
    "outputs" : [ {
      "id" : 77310,
      "points" : [ {
        "x" : 2178,
        "y" : 506
      } ]
    }, {
      "id" : 77317,
      "points" : [ {
        "x" : 2158,
        "y" : 529
      } ]
    } ],
    "catalysts" : [ {
      "id" : 77308,
      "points" : [ {
        "x" : 2028,
        "y" : 483
      }, {
        "x" : 2071,
        "y" : 470
      } ]
    } ]
  }, {
    "id" : 77378,
    "reactomeId" : 10057707,
    "displayName" : "LIG1 bound to APEX1 and PCNA ligates SSB",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2470,
      "y" : 1318
    },
    "minX" : 2464,
    "maxX" : 2476,
    "minY" : 1274,
    "maxY" : 1351,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2466,
        "y" : 1274
      },
      "to" : {
        "x" : 2470,
        "y" : 1318
      }
    }, {
      "from" : {
        "x" : 2470,
        "y" : 1318
      },
      "to" : {
        "x" : 2472,
        "y" : 1351
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2468,
        "y" : 1344
      },
      "b" : {
        "x" : 2472,
        "y" : 1351
      },
      "c" : {
        "x" : 2476,
        "y" : 1344
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2476,
        "y" : 1344
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 2464,
        "y" : 1312
      },
      "b" : {
        "x" : 2476,
        "y" : 1324
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2470,
        "y" : 1318
      }
    },
    "inputs" : [ {
      "id" : 77377
    } ],
    "outputs" : [ {
      "id" : 77379
    } ],
    "catalysts" : [ {
      "id" : 77377,
      "points" : [ {
        "x" : 2436,
        "y" : 1274
      }, {
        "x" : 2413,
        "y" : 1294
      } ]
    } ]
  }, {
    "id" : 77380,
    "reactomeId" : 10057710,
    "displayName" : "PARG dePARylates PARP1,PARP2",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1923,
      "y" : 775
    },
    "minX" : 1771,
    "maxX" : 2116,
    "minY" : 769,
    "maxY" : 781,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2116,
        "y" : 776
      },
      "to" : {
        "x" : 1923,
        "y" : 775
      }
    }, {
      "from" : {
        "x" : 1923,
        "y" : 775
      },
      "to" : {
        "x" : 1771,
        "y" : 776
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1917,
        "y" : 769
      },
      "b" : {
        "x" : 1929,
        "y" : 781
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1923,
        "y" : 775
      }
    },
    "inputs" : [ {
      "id" : 77381,
      "points" : [ {
        "x" : 2161,
        "y" : 750
      } ]
    }, {
      "id" : 77361,
      "points" : [ {
        "x" : 2362,
        "y" : 825
      } ]
    } ],
    "outputs" : [ {
      "id" : 77382,
      "points" : [ {
        "x" : 1727,
        "y" : 749
      } ]
    }, {
      "id" : 77347,
      "points" : [ {
        "x" : 1613,
        "y" : 816
      } ]
    } ],
    "catalysts" : [ {
      "id" : 77351,
      "points" : [ {
        "x" : 1923,
        "y" : 813
      } ]
    } ]
  }, {
    "id" : 77383,
    "reactomeId" : 10083819,
    "displayName" : "ADPRHL2 hydrolyses poly(ADP-ribose)",
    "schemaClass" : "Depolymerisation",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 465,
      "y" : 134
    },
    "minX" : 437,
    "maxX" : 509,
    "minY" : 128,
    "maxY" : 140,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 437,
        "y" : 134
      },
      "to" : {
        "x" : 465,
        "y" : 134
      }
    }, {
      "from" : {
        "x" : 465,
        "y" : 134
      },
      "to" : {
        "x" : 509,
        "y" : 134
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 465,
        "y" : 134
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 465,
        "y" : 134
      }
    },
    "inputs" : [ {
      "id" : 77384,
      "points" : [ {
        "x" : 425,
        "y" : 156
      } ]
    }, {
      "id" : 77385,
      "points" : [ {
        "x" : 416,
        "y" : 119
      } ]
    } ],
    "outputs" : [ {
      "id" : 77386,
      "points" : [ {
        "x" : 543,
        "y" : 134
      } ]
    }, {
      "id" : 77384,
      "points" : [ {
        "x" : 447,
        "y" : 156
      } ]
    } ],
    "catalysts" : [ {
      "id" : 77387,
      "points" : [ {
        "x" : 464,
        "y" : 107
      } ]
    } ]
  }, {
    "id" : 77318,
    "reactomeId" : 10057546,
    "displayName" : "NEIL1,NEIL2 displace OGG1 from AP-dsDNA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 564,
      "y" : 987
    },
    "minX" : 505,
    "maxX" : 606,
    "minY" : 981,
    "maxY" : 993,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 505,
        "y" : 989
      },
      "to" : {
        "x" : 564,
        "y" : 987
      }
    }, {
      "from" : {
        "x" : 564,
        "y" : 987
      },
      "to" : {
        "x" : 606,
        "y" : 988
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 558,
        "y" : 981
      },
      "b" : {
        "x" : 570,
        "y" : 993
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 564,
        "y" : 987
      }
    },
    "inputs" : [ {
      "id" : 77319,
      "points" : [ {
        "x" : 468,
        "y" : 1016
      } ]
    }, {
      "id" : 77289,
      "points" : [ {
        "x" : 454,
        "y" : 972
      } ]
    } ],
    "outputs" : [ {
      "id" : 77290,
      "points" : [ {
        "x" : 657,
        "y" : 972
      } ]
    }, {
      "id" : 77320,
      "points" : [ {
        "x" : 648,
        "y" : 1015
      } ]
    } ]
  }, {
    "id" : 77321,
    "reactomeId" : 10057572,
    "displayName" : "NEIL1,NEIL2 incises DNA strand 5' to the AP site",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 786,
      "y" : 1038
    },
    "minX" : 726,
    "maxX" : 908,
    "minY" : 982,
    "maxY" : 1044,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 726,
        "y" : 1037
      },
      "to" : {
        "x" : 786,
        "y" : 1038
      }
    }, {
      "from" : {
        "x" : 786,
        "y" : 1038
      },
      "to" : {
        "x" : 908,
        "y" : 982
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 903,
        "y" : 989
      },
      "b" : {
        "x" : 908,
        "y" : 982
      },
      "c" : {
        "x" : 900,
        "y" : 981
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 900,
        "y" : 981
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 780,
        "y" : 1032
      },
      "b" : {
        "x" : 792,
        "y" : 1044
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 786,
        "y" : 1038
      }
    },
    "inputs" : [ {
      "id" : 77320
    } ],
    "outputs" : [ {
      "id" : 77322
    } ],
    "catalysts" : [ {
      "id" : 77320,
      "points" : [ {
        "x" : 726,
        "y" : 1024
      }, {
        "x" : 753,
        "y" : 1017
      } ]
    } ]
  }, {
    "id" : 77323,
    "reactomeId" : 10057569,
    "displayName" : "NEIL1,NEIL2 recruits POLB to incised AP site",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1376,
      "y" : 760
    },
    "minX" : 1370,
    "maxX" : 1382,
    "minY" : 627,
    "maxY" : 766,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1377,
        "y" : 759
      },
      "to" : {
        "x" : 1376,
        "y" : 760
      }
    }, {
      "from" : {
        "x" : 1376,
        "y" : 760
      },
      "to" : {
        "x" : 1375,
        "y" : 627
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1379,
        "y" : 634
      },
      "b" : {
        "x" : 1375,
        "y" : 627
      },
      "c" : {
        "x" : 1371,
        "y" : 634
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1371,
        "y" : 634
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1376,
        "y" : 760
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1376,
        "y" : 760
      }
    },
    "inputs" : [ {
      "id" : 77300,
      "points" : [ {
        "x" : 1308,
        "y" : 690
      } ]
    }, {
      "id" : 77322,
      "points" : [ {
        "x" : 963,
        "y" : 950
      } ]
    } ],
    "outputs" : [ {
      "id" : 77324
    } ]
  }, {
    "id" : 77325,
    "reactomeId" : 10057561,
    "displayName" : "PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1943,
      "y" : 596
    },
    "minX" : 1921,
    "maxX" : 1965,
    "minY" : 590,
    "maxY" : 602,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1921,
        "y" : 597
      },
      "to" : {
        "x" : 1943,
        "y" : 596
      }
    }, {
      "from" : {
        "x" : 1943,
        "y" : 596
      },
      "to" : {
        "x" : 1965,
        "y" : 596
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1937,
        "y" : 590
      },
      "b" : {
        "x" : 1949,
        "y" : 602
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1943,
        "y" : 596
      }
    },
    "inputs" : [ {
      "id" : 77326,
      "points" : [ {
        "x" : 1898,
        "y" : 599
      } ]
    }, {
      "id" : 77327,
      "points" : [ {
        "x" : 1915,
        "y" : 626
      } ]
    } ],
    "outputs" : [ {
      "id" : 77328,
      "points" : [ {
        "x" : 1994,
        "y" : 598
      } ]
    }, {
      "id" : 77329,
      "points" : [ {
        "x" : 1977,
        "y" : 630
      } ]
    } ],
    "catalysts" : [ {
      "id" : 77326,
      "points" : [ {
        "x" : 1882,
        "y" : 578
      }, {
        "x" : 1923,
        "y" : 561
      } ]
    } ]
  }, {
    "id" : 77330,
    "reactomeId" : 10057584,
    "displayName" : "LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1711,
      "y" : 596
    },
    "minX" : 1705,
    "maxX" : 1760,
    "minY" : 590,
    "maxY" : 602,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1725,
        "y" : 597
      },
      "to" : {
        "x" : 1711,
        "y" : 596
      }
    }, {
      "from" : {
        "x" : 1711,
        "y" : 596
      },
      "to" : {
        "x" : 1760,
        "y" : 600
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1753,
        "y" : 603
      },
      "b" : {
        "x" : 1760,
        "y" : 600
      },
      "c" : {
        "x" : 1753,
        "y" : 595
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1753,
        "y" : 595
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1711,
        "y" : 596
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1711,
        "y" : 596
      }
    },
    "inputs" : [ {
      "id" : 77307,
      "points" : [ {
        "x" : 1822,
        "y" : 450
      } ]
    }, {
      "id" : 77331,
      "points" : [ {
        "x" : 1685,
        "y" : 599
      } ]
    }, {
      "id" : 77332,
      "points" : [ {
        "x" : 1714,
        "y" : 623
      } ]
    } ],
    "outputs" : [ {
      "id" : 77326
    } ]
  }, {
    "id" : 77333,
    "reactomeId" : 10057577,
    "displayName" : "POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2153,
      "y" : 600
    },
    "minX" : 2136,
    "maxX" : 2188,
    "minY" : 594,
    "maxY" : 606,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2136,
        "y" : 599
      },
      "to" : {
        "x" : 2153,
        "y" : 600
      }
    }, {
      "from" : {
        "x" : 2153,
        "y" : 600
      },
      "to" : {
        "x" : 2188,
        "y" : 598
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2147,
        "y" : 594
      },
      "b" : {
        "x" : 2159,
        "y" : 606
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2153,
        "y" : 600
      }
    },
    "inputs" : [ {
      "id" : 77316,
      "points" : [ {
        "x" : 2107,
        "y" : 559
      } ]
    }, {
      "id" : 77328,
      "points" : [ {
        "x" : 2118,
        "y" : 600
      } ]
    } ],
    "outputs" : [ {
      "id" : 77334,
      "points" : [ {
        "x" : 2220,
        "y" : 599
      } ]
    }, {
      "id" : 77317,
      "points" : [ {
        "x" : 2176,
        "y" : 561
      } ]
    } ],
    "catalysts" : [ {
      "id" : 77328,
      "points" : [ {
        "x" : 2114,
        "y" : 631
      }, {
        "x" : 2131,
        "y" : 635
      } ]
    } ]
  }, {
    "id" : 77335,
    "reactomeId" : 10057587,
    "displayName" : "LIG3 ligates NEIL1,NEIL2-generated single strand break",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2392,
      "y" : 604
    },
    "minX" : 2345,
    "maxX" : 2421,
    "minY" : 598,
    "maxY" : 610,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2345,
        "y" : 603
      },
      "to" : {
        "x" : 2392,
        "y" : 604
      }
    }, {
      "from" : {
        "x" : 2392,
        "y" : 604
      },
      "to" : {
        "x" : 2421,
        "y" : 603
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2414,
        "y" : 607
      },
      "b" : {
        "x" : 2421,
        "y" : 603
      },
      "c" : {
        "x" : 2414,
        "y" : 599
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2414,
        "y" : 599
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 2386,
        "y" : 598
      },
      "b" : {
        "x" : 2398,
        "y" : 610
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2392,
        "y" : 604
      }
    },
    "inputs" : [ {
      "id" : 77334
    } ],
    "outputs" : [ {
      "id" : 77336
    } ],
    "catalysts" : [ {
      "id" : 77334,
      "points" : [ {
        "x" : 2345,
        "y" : 585
      }, {
        "x" : 2368,
        "y" : 578
      } ]
    } ]
  }, {
    "id" : 77337,
    "reactomeId" : 10057582,
    "displayName" : "POLB excises the NEIL1,NEIL2-bound AP site (5'dRP)",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1486,
      "y" : 603
    },
    "minX" : 1438,
    "maxX" : 1507,
    "minY" : 597,
    "maxY" : 609,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1438,
        "y" : 601
      },
      "to" : {
        "x" : 1486,
        "y" : 603
      }
    }, {
      "from" : {
        "x" : 1486,
        "y" : 603
      },
      "to" : {
        "x" : 1507,
        "y" : 603
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1480,
        "y" : 597
      },
      "b" : {
        "x" : 1492,
        "y" : 609
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1486,
        "y" : 603
      }
    },
    "inputs" : [ {
      "id" : 77324
    } ],
    "outputs" : [ {
      "id" : 77303,
      "points" : [ {
        "x" : 1567,
        "y" : 562
      } ]
    }, {
      "id" : 77331,
      "points" : [ {
        "x" : 1560,
        "y" : 603
      } ]
    } ],
    "catalysts" : [ {
      "id" : 77324,
      "points" : [ {
        "x" : 1438,
        "y" : 577
      }, {
        "x" : 1464,
        "y" : 567
      } ]
    } ]
  }, {
    "id" : 77274,
    "reactomeId" : 9992042,
    "displayName" : "Displacement of UNG glycosylase by APEX1 at the AP site",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 569,
      "y" : 393
    },
    "minX" : 481,
    "maxX" : 602,
    "minY" : 380,
    "maxY" : 399,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 481,
        "y" : 393
      },
      "to" : {
        "x" : 569,
        "y" : 393
      }
    }, {
      "from" : {
        "x" : 569,
        "y" : 393
      },
      "to" : {
        "x" : 602,
        "y" : 380
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 563,
        "y" : 387
      },
      "b" : {
        "x" : 575,
        "y" : 399
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 569,
        "y" : 393
      }
    },
    "inputs" : [ {
      "id" : 77275,
      "points" : [ {
        "x" : 301,
        "y" : 643
      }, {
        "x" : 378,
        "y" : 395
      } ]
    }, {
      "id" : 77276,
      "points" : [ {
        "x" : 464,
        "y" : 376
      } ]
    } ],
    "outputs" : [ {
      "id" : 77277,
      "points" : [ {
        "x" : 621,
        "y" : 361
      } ]
    }, {
      "id" : 77278,
      "points" : [ {
        "x" : 872,
        "y" : 578
      }, {
        "x" : 783,
        "y" : 439
      } ]
    } ]
  }, {
    "id" : 77338,
    "reactomeId" : 10057632,
    "displayName" : "Oxidative damage to the AP site",
    "schemaClass" : "BlackBoxEvent",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1133,
      "y" : 643
    },
    "minX" : 1127,
    "maxX" : 1139,
    "minY" : 609,
    "maxY" : 681,
    "reactionType" : "omitted",
    "segments" : [ {
      "from" : {
        "x" : 1133,
        "y" : 609
      },
      "to" : {
        "x" : 1133,
        "y" : 643
      }
    }, {
      "from" : {
        "x" : 1133,
        "y" : 643
      },
      "to" : {
        "x" : 1135,
        "y" : 681
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1131,
        "y" : 674
      },
      "b" : {
        "x" : 1135,
        "y" : 681
      },
      "c" : {
        "x" : 1139,
        "y" : 674
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1139,
        "y" : 674
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 1127,
        "y" : 637
      },
      "b" : {
        "x" : 1139,
        "y" : 649
      },
      "s" : "\\\\",
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1133,
        "y" : 643
      }
    },
    "inputs" : [ {
      "id" : 77298
    } ],
    "outputs" : [ {
      "id" : 77339
    } ]
  }, {
    "id" : 77340,
    "reactomeId" : 10057630,
    "displayName" : "Recruitment of POLB to oxidatively damaged AP site",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1217,
      "y" : 793
    },
    "minX" : 1211,
    "maxX" : 1223,
    "minY" : 771,
    "maxY" : 903,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1217,
        "y" : 771
      },
      "to" : {
        "x" : 1217,
        "y" : 793
      }
    }, {
      "from" : {
        "x" : 1217,
        "y" : 793
      },
      "to" : {
        "x" : 1217,
        "y" : 903
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1213,
        "y" : 896
      },
      "b" : {
        "x" : 1217,
        "y" : 903
      },
      "c" : {
        "x" : 1221,
        "y" : 896
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1221,
        "y" : 896
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1217,
        "y" : 793
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1217,
        "y" : 793
      }
    },
    "inputs" : [ {
      "id" : 77300,
      "points" : [ {
        "x" : 1282,
        "y" : 690
      } ]
    }, {
      "id" : 77339,
      "points" : [ {
        "x" : 1169,
        "y" : 737
      } ]
    } ],
    "outputs" : [ {
      "id" : 77341
    } ]
  }, {
    "id" : 77279,
    "reactomeId" : 9992044,
    "displayName" : "Displacement of TDG glycosylase by APEX1 at the AP site",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 567,
      "y" : 456
    },
    "minX" : 500,
    "maxX" : 598,
    "minY" : 450,
    "maxY" : 462,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 500,
        "y" : 457
      },
      "to" : {
        "x" : 567,
        "y" : 456
      }
    }, {
      "from" : {
        "x" : 567,
        "y" : 456
      },
      "to" : {
        "x" : 598,
        "y" : 456
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 561,
        "y" : 450
      },
      "b" : {
        "x" : 573,
        "y" : 462
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 567,
        "y" : 456
      }
    },
    "inputs" : [ {
      "id" : 77275,
      "points" : [ {
        "x" : 304,
        "y" : 643
      }, {
        "x" : 408,
        "y" : 456
      } ]
    }, {
      "id" : 77280,
      "points" : [ {
        "x" : 488,
        "y" : 441
      } ]
    } ],
    "outputs" : [ {
      "id" : 77278,
      "points" : [ {
        "x" : 866,
        "y" : 578
      }, {
        "x" : 722,
        "y" : 457
      } ]
    }, {
      "id" : 77281,
      "points" : [ {
        "x" : 609,
        "y" : 440
      } ]
    } ]
  }, {
    "id" : 77342,
    "reactomeId" : 9992117,
    "displayName" : "POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1325,
      "y" : 929
    },
    "minX" : 1293,
    "maxX" : 1351,
    "minY" : 923,
    "maxY" : 935,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1293,
        "y" : 929
      },
      "to" : {
        "x" : 1325,
        "y" : 929
      }
    }, {
      "from" : {
        "x" : 1325,
        "y" : 929
      },
      "to" : {
        "x" : 1351,
        "y" : 928
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1319,
        "y" : 923
      },
      "b" : {
        "x" : 1331,
        "y" : 935
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1325,
        "y" : 929
      }
    },
    "inputs" : [ {
      "id" : 77341,
      "points" : [ {
        "x" : 1262,
        "y" : 929
      } ]
    }, {
      "id" : 77343,
      "points" : [ {
        "x" : 1277,
        "y" : 960
      } ]
    } ],
    "outputs" : [ {
      "id" : 77344,
      "points" : [ {
        "x" : 1398,
        "y" : 928
      } ]
    }, {
      "id" : 77345,
      "points" : [ {
        "x" : 1364,
        "y" : 959
      } ]
    } ],
    "catalysts" : [ {
      "id" : 77341,
      "points" : [ {
        "x" : 1262,
        "y" : 907
      }, {
        "x" : 1291,
        "y" : 889
      } ]
    } ]
  }, {
    "id" : 77282,
    "reactomeId" : 9992048,
    "displayName" : "Displacement of SMUG1 glycosylase by APEX1 at the AP site",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 583,
      "y" : 544
    },
    "minX" : 530,
    "maxX" : 627,
    "minY" : 538,
    "maxY" : 550,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 530,
        "y" : 544
      },
      "to" : {
        "x" : 583,
        "y" : 544
      }
    }, {
      "from" : {
        "x" : 583,
        "y" : 544
      },
      "to" : {
        "x" : 627,
        "y" : 544
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 577,
        "y" : 538
      },
      "b" : {
        "x" : 589,
        "y" : 550
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 583,
        "y" : 544
      }
    },
    "inputs" : [ {
      "id" : 77283,
      "points" : [ {
        "x" : 510,
        "y" : 514
      } ]
    }, {
      "id" : 77275,
      "points" : [ {
        "x" : 312,
        "y" : 643
      }, {
        "x" : 435,
        "y" : 542
      } ]
    } ],
    "outputs" : [ {
      "id" : 77284,
      "points" : [ {
        "x" : 641,
        "y" : 521
      } ]
    }, {
      "id" : 77278,
      "points" : [ {
        "x" : 842,
        "y" : 578
      }, {
        "x" : 719,
        "y" : 541
      } ]
    } ]
  }, {
    "id" : 77346,
    "reactomeId" : 10057648,
    "displayName" : "PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1608,
      "y" : 931
    },
    "minX" : 1578,
    "maxX" : 1633,
    "minY" : 925,
    "maxY" : 937,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1578,
        "y" : 930
      },
      "to" : {
        "x" : 1608,
        "y" : 931
      }
    }, {
      "from" : {
        "x" : 1608,
        "y" : 931
      },
      "to" : {
        "x" : 1633,
        "y" : 932
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 1608,
        "y" : 931
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1608,
        "y" : 931
      }
    },
    "inputs" : [ {
      "id" : 77347,
      "points" : [ {
        "x" : 1581,
        "y" : 850
      } ]
    }, {
      "id" : 77344,
      "points" : [ {
        "x" : 1539,
        "y" : 929
      } ]
    }, {
      "id" : 77348,
      "points" : [ {
        "x" : 1543,
        "y" : 986
      } ]
    } ],
    "outputs" : [ {
      "id" : 77349,
      "points" : [ {
        "x" : 1694,
        "y" : 933
      } ]
    }, {
      "id" : 77350,
      "points" : [ {
        "x" : 1681,
        "y" : 865
      } ]
    } ],
    "activators" : [ {
      "id" : 77351,
      "points" : [ {
        "x" : 1900,
        "y" : 826
      }, {
        "x" : 1642,
        "y" : 824
      } ]
    } ]
  }, {
    "id" : 77285,
    "reactomeId" : 9992050,
    "displayName" : "Displacement of NTHL1 glycosylase by APEX1 at the AP site",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 590,
      "y" : 625
    },
    "minX" : 508,
    "maxX" : 662,
    "minY" : 619,
    "maxY" : 631,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 508,
        "y" : 619
      },
      "to" : {
        "x" : 590,
        "y" : 625
      }
    }, {
      "from" : {
        "x" : 590,
        "y" : 625
      },
      "to" : {
        "x" : 662,
        "y" : 624
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 584,
        "y" : 619
      },
      "b" : {
        "x" : 596,
        "y" : 631
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 590,
        "y" : 625
      }
    },
    "inputs" : [ {
      "id" : 77286,
      "points" : [ {
        "x" : 496,
        "y" : 594
      } ]
    }, {
      "id" : 77275,
      "points" : [ {
        "x" : 337,
        "y" : 651
      } ]
    } ],
    "outputs" : [ {
      "id" : 77278,
      "points" : [ {
        "x" : 817,
        "y" : 601
      } ]
    }, {
      "id" : 77287,
      "points" : [ {
        "x" : 674,
        "y" : 589
      } ]
    } ]
  }, {
    "id" : 77288,
    "reactomeId" : 9992054,
    "displayName" : "Displacement of OGG1 glycosylase by APEX1 at the AP site",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 569,
      "y" : 920
    },
    "minX" : 440,
    "maxX" : 663,
    "minY" : 914,
    "maxY" : 926,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 440,
        "y" : 917
      },
      "to" : {
        "x" : 569,
        "y" : 920
      }
    }, {
      "from" : {
        "x" : 569,
        "y" : 920
      },
      "to" : {
        "x" : 663,
        "y" : 926
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 563,
        "y" : 914
      },
      "b" : {
        "x" : 575,
        "y" : 926
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 569,
        "y" : 920
      }
    },
    "inputs" : [ {
      "id" : 77289,
      "points" : [ {
        "x" : 428,
        "y" : 939
      } ]
    }, {
      "id" : 77275,
      "points" : [ {
        "x" : 299,
        "y" : 674
      }, {
        "x" : 338,
        "y" : 911
      } ]
    } ],
    "outputs" : [ {
      "id" : 77278,
      "points" : [ {
        "x" : 877,
        "y" : 608
      }, {
        "x" : 806,
        "y" : 926
      } ]
    }, {
      "id" : 77290,
      "points" : [ {
        "x" : 683,
        "y" : 950
      } ]
    } ]
  }, {
    "id" : 77352,
    "reactomeId" : 10057654,
    "displayName" : "POLB-mediated DNA strand displacement synthesis",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1874,
      "y" : 930
    },
    "minX" : 1851,
    "maxX" : 1904,
    "minY" : 924,
    "maxY" : 936,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1851,
        "y" : 930
      },
      "to" : {
        "x" : 1874,
        "y" : 930
      }
    }, {
      "from" : {
        "x" : 1874,
        "y" : 930
      },
      "to" : {
        "x" : 1904,
        "y" : 930
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1868,
        "y" : 924
      },
      "b" : {
        "x" : 1880,
        "y" : 936
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1874,
        "y" : 930
      }
    },
    "inputs" : [ {
      "id" : 77349,
      "points" : [ {
        "x" : 1824,
        "y" : 931
      } ]
    }, {
      "id" : 77353,
      "points" : [ {
        "x" : 1835,
        "y" : 980
      } ],
      "stoichiometry" : 10
    } ],
    "outputs" : [ {
      "id" : 77354,
      "points" : [ {
        "x" : 1937,
        "y" : 930
      } ]
    }, {
      "id" : 77355,
      "points" : [ {
        "x" : 1918,
        "y" : 980
      } ],
      "stoichiometry" : 10
    } ],
    "catalysts" : [ {
      "id" : 77349,
      "points" : [ {
        "x" : 1799,
        "y" : 898
      }, {
        "x" : 1823,
        "y" : 882
      } ]
    } ]
  }, {
    "id" : 77291,
    "reactomeId" : 9992056,
    "displayName" : "Displacement of MUTYH glycosylase by APEX1 at the AP site",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 608,
      "y" : 754
    },
    "minX" : 466,
    "maxX" : 722,
    "minY" : 748,
    "maxY" : 764,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 466,
        "y" : 764
      },
      "to" : {
        "x" : 608,
        "y" : 754
      }
    }, {
      "from" : {
        "x" : 608,
        "y" : 754
      },
      "to" : {
        "x" : 722,
        "y" : 753
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 602,
        "y" : 748
      },
      "b" : {
        "x" : 614,
        "y" : 760
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 608,
        "y" : 754
      }
    },
    "inputs" : [ {
      "id" : 77275,
      "points" : [ {
        "x" : 309,
        "y" : 674
      }, {
        "x" : 391,
        "y" : 762
      } ]
    }, {
      "id" : 77292,
      "points" : [ {
        "x" : 452,
        "y" : 786
      } ]
    } ],
    "outputs" : [ {
      "id" : 77278,
      "points" : [ {
        "x" : 868,
        "y" : 608
      } ]
    }, {
      "id" : 77293,
      "points" : [ {
        "x" : 740,
        "y" : 780
      } ]
    } ]
  }, {
    "id" : 77356,
    "reactomeId" : 10057687,
    "displayName" : "PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2164,
      "y" : 927
    },
    "minX" : 2140,
    "maxX" : 2186,
    "minY" : 921,
    "maxY" : 933,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2140,
        "y" : 927
      },
      "to" : {
        "x" : 2164,
        "y" : 927
      }
    }, {
      "from" : {
        "x" : 2164,
        "y" : 927
      },
      "to" : {
        "x" : 2186,
        "y" : 929
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 2158,
        "y" : 921
      },
      "b" : {
        "x" : 2170,
        "y" : 933
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2164,
        "y" : 927
      }
    },
    "inputs" : [ {
      "id" : 77357,
      "points" : [ {
        "x" : 2129,
        "y" : 975
      } ]
    }, {
      "id" : 77354,
      "points" : [ {
        "x" : 2118,
        "y" : 928
      } ]
    } ],
    "outputs" : [ {
      "id" : 77358,
      "points" : [ {
        "x" : 2199,
        "y" : 973
      } ]
    }, {
      "id" : 77359,
      "points" : [ {
        "x" : 2243,
        "y" : 927
      } ]
    } ],
    "catalysts" : [ {
      "id" : 77354,
      "points" : [ {
        "x" : 2100,
        "y" : 898
      }, {
        "x" : 2139,
        "y" : 884
      } ]
    } ]
  }, {
    "id" : 77294,
    "reactomeId" : 9992058,
    "displayName" : "Displacement of MPG glycosylase by APEX1 at the AP site",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 573,
      "y" : 836
    },
    "minX" : 433,
    "maxX" : 680,
    "minY" : 830,
    "maxY" : 842,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 433,
        "y" : 834
      },
      "to" : {
        "x" : 573,
        "y" : 836
      }
    }, {
      "from" : {
        "x" : 573,
        "y" : 836
      },
      "to" : {
        "x" : 680,
        "y" : 839
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 567,
        "y" : 830
      },
      "b" : {
        "x" : 579,
        "y" : 842
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 573,
        "y" : 836
      }
    },
    "inputs" : [ {
      "id" : 77295,
      "points" : [ {
        "x" : 416,
        "y" : 863
      } ]
    }, {
      "id" : 77275,
      "points" : [ {
        "x" : 302,
        "y" : 674
      }, {
        "x" : 367,
        "y" : 834
      } ]
    } ],
    "outputs" : [ {
      "id" : 77296,
      "points" : [ {
        "x" : 711,
        "y" : 873
      } ]
    }, {
      "id" : 77278,
      "points" : [ {
        "x" : 876,
        "y" : 608
      }, {
        "x" : 802,
        "y" : 832
      } ]
    } ]
  }, {
    "id" : 77297,
    "reactomeId" : 9992065,
    "displayName" : "APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 999,
      "y" : 591
    },
    "minX" : 944,
    "maxX" : 1025,
    "minY" : 585,
    "maxY" : 597,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 944,
        "y" : 591
      },
      "to" : {
        "x" : 999,
        "y" : 591
      }
    }, {
      "from" : {
        "x" : 999,
        "y" : 591
      },
      "to" : {
        "x" : 1025,
        "y" : 591
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1018,
        "y" : 595
      },
      "b" : {
        "x" : 1025,
        "y" : 591
      },
      "c" : {
        "x" : 1018,
        "y" : 587
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1018,
        "y" : 587
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 993,
        "y" : 585
      },
      "b" : {
        "x" : 1005,
        "y" : 597
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 999,
        "y" : 591
      }
    },
    "inputs" : [ {
      "id" : 77278
    } ],
    "outputs" : [ {
      "id" : 77298
    } ],
    "catalysts" : [ {
      "id" : 77278,
      "points" : [ {
        "x" : 908,
        "y" : 578
      }, {
        "x" : 967,
        "y" : 556
      } ]
    } ]
  }, {
    "id" : 77360,
    "reactomeId" : 10057691,
    "displayName" : "PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2379,
      "y" : 920
    },
    "minX" : 2354,
    "maxX" : 2394,
    "minY" : 914,
    "maxY" : 926,
    "reactionType" : "dissociation",
    "segments" : [ {
      "from" : {
        "x" : 2354,
        "y" : 922
      },
      "to" : {
        "x" : 2379,
        "y" : 920
      }
    }, {
      "from" : {
        "x" : 2379,
        "y" : 920
      },
      "to" : {
        "x" : 2394,
        "y" : 919
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 2379,
        "y" : 920
      },
      "r" : 5,
      "r1" : 3,
      "type" : "DOUBLE_CIRCLE",
      "empty" : true,
      "centre" : {
        "x" : 2379,
        "y" : 920
      }
    },
    "inputs" : [ {
      "id" : 77359
    } ],
    "outputs" : [ {
      "id" : 77361,
      "points" : [ {
        "x" : 2401,
        "y" : 863
      } ]
    }, {
      "id" : 77362,
      "points" : [ {
        "x" : 2423,
        "y" : 919
      } ]
    } ]
  }, {
    "id" : 77299,
    "reactomeId" : 9992069,
    "displayName" : "Recruitment of POLB to the AP site",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1302,
      "y" : 562
    },
    "minX" : 1264,
    "maxX" : 1334,
    "minY" : 523,
    "maxY" : 608,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1270,
        "y" : 602
      },
      "to" : {
        "x" : 1302,
        "y" : 562
      }
    }, {
      "from" : {
        "x" : 1302,
        "y" : 562
      },
      "to" : {
        "x" : 1334,
        "y" : 523
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1333,
        "y" : 531
      },
      "b" : {
        "x" : 1334,
        "y" : 523
      },
      "c" : {
        "x" : 1327,
        "y" : 526
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1327,
        "y" : 526
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1302,
        "y" : 562
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1302,
        "y" : 562
      }
    },
    "inputs" : [ {
      "id" : 77298,
      "points" : [ {
        "x" : 1243,
        "y" : 600
      } ]
    }, {
      "id" : 77300,
      "points" : [ {
        "x" : 1288,
        "y" : 653
      } ]
    } ],
    "outputs" : [ {
      "id" : 77301
    } ]
  }, {
    "id" : 77363,
    "reactomeId" : 10057697,
    "displayName" : "LIG1 binds POLB at long-patch BER site",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2672,
      "y" : 1050
    },
    "minX" : 2666,
    "maxX" : 2678,
    "minY" : 1029,
    "maxY" : 1087,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2671,
        "y" : 1029
      },
      "to" : {
        "x" : 2672,
        "y" : 1050
      }
    }, {
      "from" : {
        "x" : 2672,
        "y" : 1050
      },
      "to" : {
        "x" : 2674,
        "y" : 1087
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2670,
        "y" : 1080
      },
      "b" : {
        "x" : 2674,
        "y" : 1087
      },
      "c" : {
        "x" : 2678,
        "y" : 1080
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2678,
        "y" : 1080
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2672,
        "y" : 1050
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2672,
        "y" : 1050
      }
    },
    "inputs" : [ {
      "id" : 77364,
      "points" : [ {
        "x" : 2674,
        "y" : 1004
      } ]
    }, {
      "id" : 77365,
      "points" : [ {
        "x" : 2633,
        "y" : 1048
      } ]
    } ],
    "outputs" : [ {
      "id" : 77366
    } ]
  }, {
    "id" : 77367,
    "reactomeId" : 10057702,
    "displayName" : "LIG1 bound to POLB ligates SSB",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2673,
      "y" : 1201
    },
    "minX" : 2667,
    "maxX" : 2679,
    "minY" : 1156,
    "maxY" : 1242,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2675,
        "y" : 1156
      },
      "to" : {
        "x" : 2673,
        "y" : 1201
      }
    }, {
      "from" : {
        "x" : 2673,
        "y" : 1201
      },
      "to" : {
        "x" : 2675,
        "y" : 1242
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2671,
        "y" : 1235
      },
      "b" : {
        "x" : 2675,
        "y" : 1242
      },
      "c" : {
        "x" : 2679,
        "y" : 1235
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2679,
        "y" : 1235
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 2667,
        "y" : 1195
      },
      "b" : {
        "x" : 2679,
        "y" : 1207
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2673,
        "y" : 1201
      }
    },
    "inputs" : [ {
      "id" : 77366
    } ],
    "outputs" : [ {
      "id" : 77368
    } ],
    "catalysts" : [ {
      "id" : 77366,
      "points" : [ {
        "x" : 2658,
        "y" : 1156
      }, {
        "x" : 2642,
        "y" : 1181
      } ]
    } ]
  }, {
    "id" : 77302,
    "reactomeId" : 9992099,
    "displayName" : "Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1509,
      "y" : 486
    },
    "minX" : 1459,
    "maxX" : 1537,
    "minY" : 480,
    "maxY" : 492,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1459,
        "y" : 489
      },
      "to" : {
        "x" : 1509,
        "y" : 486
      }
    }, {
      "from" : {
        "x" : 1509,
        "y" : 486
      },
      "to" : {
        "x" : 1537,
        "y" : 488
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1503,
        "y" : 480
      },
      "b" : {
        "x" : 1515,
        "y" : 492
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1509,
        "y" : 486
      }
    },
    "inputs" : [ {
      "id" : 77301
    } ],
    "outputs" : [ {
      "id" : 77303,
      "points" : [ {
        "x" : 1574,
        "y" : 525
      } ]
    }, {
      "id" : 77304,
      "points" : [ {
        "x" : 1601,
        "y" : 493
      } ]
    }, {
      "id" : 77305,
      "points" : [ {
        "x" : 1580,
        "y" : 438
      } ]
    } ],
    "catalysts" : [ {
      "id" : 77301,
      "points" : [ {
        "x" : 1372,
        "y" : 489
      }, {
        "x" : 1465,
        "y" : 444
      } ]
    } ]
  }, {
    "id" : 77369,
    "reactomeId" : 9992085,
    "displayName" : "PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1504,
      "y" : 1111
    },
    "minX" : 1471,
    "maxX" : 1533,
    "minY" : 1105,
    "maxY" : 1117,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1471,
        "y" : 1111
      },
      "to" : {
        "x" : 1504,
        "y" : 1111
      }
    }, {
      "from" : {
        "x" : 1504,
        "y" : 1111
      },
      "to" : {
        "x" : 1533,
        "y" : 1110
      }
    } ],
    "reactionShape" : {
      "c" : {
        "x" : 1504,
        "y" : 1111
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1504,
        "y" : 1111
      }
    },
    "inputs" : [ {
      "id" : 77370,
      "points" : [ {
        "x" : 1402,
        "y" : 1111
      } ]
    }, {
      "id" : 77348,
      "points" : [ {
        "x" : 1530,
        "y" : 1014
      } ]
    }, {
      "id" : 77344,
      "points" : [ {
        "x" : 1468,
        "y" : 958
      } ]
    } ],
    "outputs" : [ {
      "id" : 77371,
      "points" : [ {
        "x" : 1570,
        "y" : 1111
      } ]
    }, {
      "id" : 77372,
      "points" : [ {
        "x" : 1559,
        "y" : 1071
      } ]
    } ]
  }, {
    "id" : 77306,
    "reactomeId" : 9992101,
    "displayName" : "Recruitment of LIG3:XRCC1 complex to the site of repair by POLB",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1827,
      "y" : 503
    },
    "minX" : 1806,
    "maxX" : 1911,
    "minY" : 497,
    "maxY" : 509,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 1806,
        "y" : 504
      },
      "to" : {
        "x" : 1827,
        "y" : 503
      }
    }, {
      "from" : {
        "x" : 1827,
        "y" : 503
      },
      "to" : {
        "x" : 1911,
        "y" : 504
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 1904,
        "y" : 508
      },
      "b" : {
        "x" : 1911,
        "y" : 504
      },
      "c" : {
        "x" : 1904,
        "y" : 500
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 1904,
        "y" : 500
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 1827,
        "y" : 503
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 1827,
        "y" : 503
      }
    },
    "inputs" : [ {
      "id" : 77304,
      "points" : [ {
        "x" : 1763,
        "y" : 502
      } ]
    }, {
      "id" : 77307,
      "points" : [ {
        "x" : 1825,
        "y" : 450
      } ]
    } ],
    "outputs" : [ {
      "id" : 77308
    } ]
  }, {
    "id" : 77373,
    "reactomeId" : 9992088,
    "displayName" : "POLD,POLE-mediated DNA strand displacement synthesis",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 1833,
      "y" : 1107
    },
    "minX" : 1779,
    "maxX" : 1870,
    "minY" : 1101,
    "maxY" : 1113,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 1779,
        "y" : 1110
      },
      "to" : {
        "x" : 1833,
        "y" : 1107
      }
    }, {
      "from" : {
        "x" : 1833,
        "y" : 1107
      },
      "to" : {
        "x" : 1870,
        "y" : 1106
      }
    } ],
    "reactionShape" : {
      "a" : {
        "x" : 1827,
        "y" : 1101
      },
      "b" : {
        "x" : 1839,
        "y" : 1113
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 1833,
        "y" : 1107
      }
    },
    "inputs" : [ {
      "id" : 77371,
      "points" : [ {
        "x" : 1720,
        "y" : 1111
      } ]
    }, {
      "id" : 77353,
      "points" : [ {
        "x" : 1825,
        "y" : 1013
      } ],
      "stoichiometry" : 10
    } ],
    "outputs" : [ {
      "id" : 77374,
      "points" : [ {
        "x" : 1919,
        "y" : 1104
      } ]
    }, {
      "id" : 77355,
      "points" : [ {
        "x" : 1915,
        "y" : 1012
      } ],
      "stoichiometry" : 10
    } ],
    "catalysts" : [ {
      "id" : 77371,
      "points" : [ {
        "x" : 1720,
        "y" : 1134
      }, {
        "x" : 1763,
        "y" : 1147
      } ]
    } ]
  }, {
    "id" : 77309,
    "reactomeId" : 9988604,
    "displayName" : "LIG3-mediated DNA ligation via the single-nucleotide replacement pathway",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2346,
      "y" : 499
    },
    "minX" : 2302,
    "maxX" : 2386,
    "minY" : 493,
    "maxY" : 505,
    "reactionType" : "transition",
    "segments" : [ {
      "from" : {
        "x" : 2302,
        "y" : 500
      },
      "to" : {
        "x" : 2346,
        "y" : 499
      }
    }, {
      "from" : {
        "x" : 2346,
        "y" : 499
      },
      "to" : {
        "x" : 2386,
        "y" : 499
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2379,
        "y" : 503
      },
      "b" : {
        "x" : 2386,
        "y" : 499
      },
      "c" : {
        "x" : 2379,
        "y" : 495
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2379,
        "y" : 495
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 2340,
        "y" : 493
      },
      "b" : {
        "x" : 2352,
        "y" : 505
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 2346,
        "y" : 499
      }
    },
    "inputs" : [ {
      "id" : 77310
    } ],
    "outputs" : [ {
      "id" : 77311
    } ],
    "catalysts" : [ {
      "id" : 77310,
      "points" : [ {
        "x" : 2271,
        "y" : 481
      }, {
        "x" : 2325,
        "y" : 451
      } ]
    } ]
  }, {
    "id" : 77375,
    "reactomeId" : 9992096,
    "displayName" : "LIG1 binds APEX1 and PCNA at SSB",
    "schemaClass" : "Reaction",
    "renderableClass" : "Reaction",
    "position" : {
      "x" : 2461,
      "y" : 1183
    },
    "minX" : 2455,
    "maxX" : 2467,
    "minY" : 1177,
    "maxY" : 1212,
    "reactionType" : "binding",
    "segments" : [ {
      "from" : {
        "x" : 2460,
        "y" : 1183
      },
      "to" : {
        "x" : 2461,
        "y" : 1183
      }
    }, {
      "from" : {
        "x" : 2461,
        "y" : 1183
      },
      "to" : {
        "x" : 2463,
        "y" : 1212
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 2459,
        "y" : 1205
      },
      "b" : {
        "x" : 2463,
        "y" : 1212
      },
      "c" : {
        "x" : 2467,
        "y" : 1205
      },
      "type" : "ARROW",
      "centre" : {
        "x" : 2467,
        "y" : 1205
      }
    },
    "reactionShape" : {
      "c" : {
        "x" : 2461,
        "y" : 1183
      },
      "r" : 5,
      "type" : "CIRCLE",
      "centre" : {
        "x" : 2461,
        "y" : 1183
      }
    },
    "inputs" : [ {
      "id" : 77376,
      "points" : [ {
        "x" : 2459,
        "y" : 1147
      } ]
    }, {
      "id" : 77365,
      "points" : [ {
        "x" : 2603,
        "y" : 1077
      }, {
        "x" : 2517,
        "y" : 1181
      } ]
    } ],
    "outputs" : [ {
      "id" : 77377
    } ]
  } ],
  "compartments" : [ {
    "id" : 77399,
    "reactomeId" : 70101,
    "displayName" : "cytosol",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1436,
      "y" : 795
    },
    "minX" : 0,
    "maxX" : 2872,
    "minY" : 0,
    "maxY" : 1590,
    "prop" : {
      "x" : 0,
      "y" : 0,
      "width" : 2872,
      "height" : 1590
    },
    "textPosition" : {
      "x" : 124,
      "y" : 44
    },
    "insets" : {
      "x" : 10,
      "y" : 10,
      "width" : 2852,
      "height" : 1570
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 77388, 77398 ]
  }, {
    "id" : 77398,
    "reactomeId" : 5460,
    "displayName" : "mitochondrial matrix",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 505,
      "y" : 120
    },
    "minX" : 349,
    "maxX" : 661,
    "minY" : 27,
    "maxY" : 214,
    "prop" : {
      "x" : 349,
      "y" : 27,
      "width" : 312,
      "height" : 187
    },
    "textPosition" : {
      "x" : 483,
      "y" : 48
    },
    "insets" : {
      "x" : 359,
      "y" : 37,
      "width" : 292,
      "height" : 167
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 77384, 77385, 77386, 77387, 77383 ]
  }, {
    "id" : 77388,
    "reactomeId" : 7660,
    "displayName" : "nucleoplasm",
    "schemaClass" : "Compartment",
    "renderableClass" : "Compartment",
    "position" : {
      "x" : 1434,
      "y" : 908
    },
    "minX" : 46,
    "maxX" : 2823,
    "minY" : 277,
    "maxY" : 1540,
    "prop" : {
      "x" : 46,
      "y" : 277,
      "width" : 2777,
      "height" : 1263
    },
    "textPosition" : {
      "x" : 111,
      "y" : 301
    },
    "insets" : {
      "x" : 56,
      "y" : 287,
      "width" : 2757,
      "height" : 1243
    },
    "bgColor" : {
      "r" : 250,
      "g" : 240,
      "b" : 240
    },
    "componentIds" : [ 77296, 77290, 77292, 77295, 77281, 77276, 77280, 77284, 77313, 77287, 77286, 77278, 77275, 77282, 77285, 77288, 77291, 77294, 77297, 77298, 77299, 77300, 77301, 77303, 77304, 77306, 77307, 77308, 77310, 77309, 77311, 77314, 77312, 77389, 77274, 77279, 77283, 77289, 77400, 77302, 77315, 77316, 77317, 77318, 77319, 77320, 77321, 77322, 77323, 77332, 77324, 77325, 77329, 77331, 77330, 77326, 77333, 77334, 77335, 77336, 77337, 77328, 77327, 77338, 77339, 77340, 77341, 77342, 77344, 77345, 77305, 77346, 77347, 77348, 77349, 77350, 77352, 77354, 77353, 77355, 77356, 77357, 77358, 77359, 77360, 77361, 77362, 77364, 77363, 77365, 77366, 77367, 77368, 77369, 77370, 77371, 77372, 77373, 77374, 77376, 77375, 77377, 77379, 77378, 77380, 77381, 77382, 77351, 77277, 77343, 77293 ]
  } ],
  "notes" : [ ],
  "links" : [ {
    "id" : 77400,
    "renderableClass" : "Interaction",
    "position" : {
      "x" : 244,
      "y" : 659
    },
    "minX" : 229,
    "maxX" : 259,
    "minY" : 653,
    "maxY" : 665,
    "interactionType" : "Activate",
    "segments" : [ {
      "from" : {
        "x" : 229,
        "y" : 660
      },
      "to" : {
        "x" : 259,
        "y" : 659
      }
    } ],
    "endShape" : {
      "a" : {
        "x" : 252,
        "y" : 663
      },
      "b" : {
        "x" : 259,
        "y" : 659
      },
      "c" : {
        "x" : 252,
        "y" : 655
      },
      "type" : "ARROW",
      "empty" : true,
      "centre" : {
        "x" : 252,
        "y" : 655
      }
    },
    "reactionShape" : {
      "a" : {
        "x" : 238,
        "y" : 653
      },
      "b" : {
        "x" : 250,
        "y" : 665
      },
      "type" : "BOX",
      "empty" : true,
      "centre" : {
        "x" : 244,
        "y" : 659
      }
    },
    "inputs" : [ {
      "id" : 77389
    } ],
    "outputs" : [ {
      "id" : 77275
    } ]
  } ],
  "shadows" : [ {
    "id" : 77401,
    "reactomeId" : 10098653,
    "displayName" : "Resolution of AP sites via the single-nucleotide replacement pathway",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1772,
      "y" : 548
    },
    "minX" : 1018,
    "maxX" : 2527,
    "minY" : 400,
    "maxY" : 697,
    "prop" : {
      "x" : 1018,
      "y" : 400,
      "width" : 1509,
      "height" : 297
    },
    "points" : [ {
      "x" : 1018,
      "y" : 400
    }, {
      "x" : 2527,
      "y" : 400
    }, {
      "x" : 2527,
      "y" : 697
    }, {
      "x" : 1018,
      "y" : 697
    } ],
    "colour" : "#4684ee"
  }, {
    "id" : 77403,
    "reactomeId" : 10098917,
    "displayName" : "Resolution of AP sites via the multiple-nucleotide patch replacement pathway",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1558,
      "y" : 736
    },
    "minX" : 357,
    "maxX" : 2760,
    "minY" : 72,
    "maxY" : 1401,
    "prop" : {
      "x" : 357,
      "y" : 1073,
      "width" : 2403,
      "height" : 328
    },
    "points" : [ {
      "x" : 357,
      "y" : 72
    }, {
      "x" : 2760,
      "y" : 72
    }, {
      "x" : 2760,
      "y" : 1401
    }, {
      "x" : 357,
      "y" : 1401
    } ],
    "colour" : "#008000"
  }, {
    "id" : 77402,
    "reactomeId" : 10098911,
    "displayName" : "Displacement of DNA glycosylase by APEX1",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 601,
      "y" : 655
    },
    "minX" : 252,
    "maxX" : 951,
    "minY" : 326,
    "maxY" : 984,
    "prop" : {
      "x" : 252,
      "y" : 326,
      "width" : 699,
      "height" : 658
    },
    "points" : [ {
      "x" : 252,
      "y" : 326
    }, {
      "x" : 951,
      "y" : 326
    }, {
      "x" : 951,
      "y" : 984
    }, {
      "x" : 252,
      "y" : 984
    } ],
    "colour" : "#dc3912"
  }, {
    "id" : 77404,
    "reactomeId" : 10101219,
    "displayName" : "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway",
    "schemaClass" : "Pathway",
    "renderableClass" : "Shadow",
    "position" : {
      "x" : 1456,
      "y" : 745
    },
    "minX" : 353,
    "maxX" : 2560,
    "minY" : 417,
    "maxY" : 1073,
    "prop" : {
      "x" : 353,
      "y" : 417,
      "width" : 2207,
      "height" : 656
    },
    "points" : [ {
      "x" : 353,
      "y" : 417
    }, {
      "x" : 2560,
      "y" : 417
    }, {
      "x" : 2560,
      "y" : 1073
    }, {
      "x" : 353,
      "y" : 1073
    } ],
    "colour" : "#666666"
  } ],
  "minX" : 0,
  "maxX" : 2872,
  "minY" : 0,
  "maxY" : 1590,
  "disease" : false
}