A0A023GPK8 R-DME-373714 https://reactome.org/PathwayBrowser/#/R-DME-373714 Cis-Heterodimerization of nephrin and KIRREL IEA Drosophila melanogaster A0A023GPK8 R-DME-373724 https://reactome.org/PathwayBrowser/#/R-DME-373724 Nephrin binds NCK IEA Drosophila melanogaster A0A023GPK8 R-DME-373734 https://reactome.org/PathwayBrowser/#/R-DME-373734 Nephrin interacts with Podocin IEA Drosophila melanogaster A0A023GPK8 R-DME-373747 https://reactome.org/PathwayBrowser/#/R-DME-373747 Phosphorylation of nephrin by FYN IEA Drosophila melanogaster A0A023GPK8 R-DME-451757 https://reactome.org/PathwayBrowser/#/R-DME-451757 Heterodimerization of nephrin and KIRREL2, KIRREL3 IEA Drosophila melanogaster A0A023GPK8 R-DME-8981534 https://reactome.org/PathwayBrowser/#/R-DME-8981534 Nephrin dimer:KIRREL binds FYN IEA Drosophila melanogaster A0A023GRW3 R-DME-72103 https://reactome.org/PathwayBrowser/#/R-DME-72103 Formation of pre-mRNPs IEA Drosophila melanogaster A0A023GRW3 R-DME-9770141 https://reactome.org/PathwayBrowser/#/R-DME-9770141 Formation of the Spliceosomal C* complex IEA Drosophila melanogaster A0A023GRW3 R-DME-9770236 https://reactome.org/PathwayBrowser/#/R-DME-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Drosophila melanogaster A0A023GRW3 R-DME-9794542 https://reactome.org/PathwayBrowser/#/R-DME-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Drosophila melanogaster A0A023IKK2 R-RNO-202165 https://reactome.org/PathwayBrowser/#/R-RNO-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Rattus norvegicus A0A023IKK2 R-RNO-202168 https://reactome.org/PathwayBrowser/#/R-RNO-202168 Phosphorylation of ZAP-70 by Lck IEA Rattus norvegicus A0A023IKK2 R-RNO-202174 https://reactome.org/PathwayBrowser/#/R-RNO-202174 Activation of ZAP-70 IEA Rattus norvegicus A0A023IKK2 R-RNO-202214 https://reactome.org/PathwayBrowser/#/R-RNO-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Rattus norvegicus A0A023IKK2 R-RNO-202216 https://reactome.org/PathwayBrowser/#/R-RNO-202216 Phosphorylation of SLP-76 IEA Rattus norvegicus A0A023IKK2 R-RNO-202233 https://reactome.org/PathwayBrowser/#/R-RNO-202233 Inactivation of Lck by Csk IEA Rattus norvegicus A0A023IKK2 R-RNO-202245 https://reactome.org/PathwayBrowser/#/R-RNO-202245 Phosphorylation of TBSMs in LAT IEA Rattus norvegicus A0A023IKK2 R-RNO-202248 https://reactome.org/PathwayBrowser/#/R-RNO-202248 Phosphorylation of PLC-gamma1 IEA Rattus norvegicus A0A023IKK2 R-RNO-202291 https://reactome.org/PathwayBrowser/#/R-RNO-202291 Activation of Lck IEA Rattus norvegicus A0A023IKK2 R-RNO-202307 https://reactome.org/PathwayBrowser/#/R-RNO-202307 Change of PKC theta conformation IEA Rattus norvegicus A0A023IKK2 R-RNO-202344 https://reactome.org/PathwayBrowser/#/R-RNO-202344 Recruitment of ZAP-70 to phosphorylated ITAMs IEA Rattus norvegicus A0A023IKK2 R-RNO-2130336 https://reactome.org/PathwayBrowser/#/R-RNO-2130336 Initial proteolyis of Ii by aspartic proteases to lip22 IEA Rattus norvegicus A0A023IKK2 R-RNO-2130349 https://reactome.org/PathwayBrowser/#/R-RNO-2130349 Generation of CLIP from lip10 IEA Rattus norvegicus A0A023IKK2 R-RNO-2130378 https://reactome.org/PathwayBrowser/#/R-RNO-2130378 Transport of MHC II:Ii complex to plasma membrane IEA Rattus norvegicus A0A023IKK2 R-RNO-2130393 https://reactome.org/PathwayBrowser/#/R-RNO-2130393 Transport of MHC II:Ii complex along Golgi to TGN IEA Rattus norvegicus A0A023IKK2 R-RNO-2130478 https://reactome.org/PathwayBrowser/#/R-RNO-2130478 Interaction of invariant chain trimer and MHC II alpha beta dimer IEA Rattus norvegicus A0A023IKK2 R-RNO-2130486 https://reactome.org/PathwayBrowser/#/R-RNO-2130486 Uncoating of clathrin-coated vesicles and fusion with endosomes IEA Rattus norvegicus A0A023IKK2 R-RNO-2130500 https://reactome.org/PathwayBrowser/#/R-RNO-2130500 Insertion of MHC II:Ii complex in to the plasma membrane IEA Rattus norvegicus A0A023IKK2 R-RNO-2130504 https://reactome.org/PathwayBrowser/#/R-RNO-2130504 Cleavage of lip22 to lip10 IEA Rattus norvegicus A0A023IKK2 R-RNO-2130619 https://reactome.org/PathwayBrowser/#/R-RNO-2130619 TGN-lysosomal vesicle coat assembly IEA Rattus norvegicus A0A023IKK2 R-RNO-2130640 https://reactome.org/PathwayBrowser/#/R-RNO-2130640 Recruitment of clathrin coated vesicle by Ii IEA Rattus norvegicus A0A023IKK2 R-RNO-2130641 https://reactome.org/PathwayBrowser/#/R-RNO-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Rattus norvegicus A0A023IKK2 R-RNO-2130725 https://reactome.org/PathwayBrowser/#/R-RNO-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Rattus norvegicus A0A023IKK2 R-RNO-2130731 https://reactome.org/PathwayBrowser/#/R-RNO-2130731 Formation of COPII vesicle IEA Rattus norvegicus A0A023IKK2 R-RNO-2213235 https://reactome.org/PathwayBrowser/#/R-RNO-2213235 Trafficking of nonameric complex in the endocytic pathway IEA Rattus norvegicus A0A023IKK2 R-RNO-2213236 https://reactome.org/PathwayBrowser/#/R-RNO-2213236 TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome IEA Rattus norvegicus A0A023IKK2 R-RNO-2213239 https://reactome.org/PathwayBrowser/#/R-RNO-2213239 Formation of MHC II alpha beta heterodimer IEA Rattus norvegicus A0A023IKK2 R-RNO-2213241 https://reactome.org/PathwayBrowser/#/R-RNO-2213241 Formation of nonameric complex IEA Rattus norvegicus A0A023IKK2 R-RNO-2213243 https://reactome.org/PathwayBrowser/#/R-RNO-2213243 Fusion of COPII vesicle with Golgi complex IEA Rattus norvegicus A0A023IKK2 R-RNO-2213244 https://reactome.org/PathwayBrowser/#/R-RNO-2213244 Loading of antigenic peptides IEA Rattus norvegicus A0A023IKK2 R-RNO-2213246 https://reactome.org/PathwayBrowser/#/R-RNO-2213246 Disassociation of CLIP from MHC II IEA Rattus norvegicus A0A023IKK2 R-RNO-2213248 https://reactome.org/PathwayBrowser/#/R-RNO-2213248 Transport of antigen loaded MHC II molecules to surface IEA Rattus norvegicus A0A023IKK2 R-RNO-389758 https://reactome.org/PathwayBrowser/#/R-RNO-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Rattus norvegicus A0A023IKK2 R-RNO-8852200 https://reactome.org/PathwayBrowser/#/R-RNO-8852200 Inactivation of LCK by PTPN22 IEA Rattus norvegicus A0A023IKK2 R-RNO-8855381 https://reactome.org/PathwayBrowser/#/R-RNO-8855381 PTPN22 dephosphorylates ZAP70 IEA Rattus norvegicus A0A023IKK2 R-RNO-8856157 https://reactome.org/PathwayBrowser/#/R-RNO-8856157 LAG3 (CD233) binds MHC II IEA Rattus norvegicus A0A023IKK2 R-RNO-8951498 https://reactome.org/PathwayBrowser/#/R-RNO-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Rattus norvegicus A0A023IKK2 R-RNO-8951500 https://reactome.org/PathwayBrowser/#/R-RNO-8951500 Dissociation of CANX from nonameric complex IEA Rattus norvegicus A0A060Q6E4 R-DRE-1650808 https://reactome.org/PathwayBrowser/#/R-DRE-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Danio rerio A0A060Q6E4 R-DRE-1981104 https://reactome.org/PathwayBrowser/#/R-DRE-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Danio rerio A0A060Q6E4 R-DRE-1981120 https://reactome.org/PathwayBrowser/#/R-DRE-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Danio rerio A0A060Q6E4 R-DRE-1981128 https://reactome.org/PathwayBrowser/#/R-DRE-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Danio rerio A0A060Q6E4 R-DRE-1981157 https://reactome.org/PathwayBrowser/#/R-DRE-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Danio rerio A0A060Q6E4 R-DRE-2002401 https://reactome.org/PathwayBrowser/#/R-DRE-2002401 Association of procollagen type XVIII IEA Danio rerio A0A060Q6E4 R-DRE-2002460 https://reactome.org/PathwayBrowser/#/R-DRE-2002460 P4HB binds Collagen chains IEA Danio rerio A0A060Q6E4 R-DRE-2089971 https://reactome.org/PathwayBrowser/#/R-DRE-2089971 Secretion of collagens IEA Danio rerio A0A060Q6E4 R-DRE-8948219 https://reactome.org/PathwayBrowser/#/R-DRE-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Danio rerio A0A060Q6E4 R-DRE-8948222 https://reactome.org/PathwayBrowser/#/R-DRE-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Danio rerio A0A060Q6E4 R-DRE-8948224 https://reactome.org/PathwayBrowser/#/R-DRE-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Danio rerio A0A060Q6E4 R-DRE-8948228 https://reactome.org/PathwayBrowser/#/R-DRE-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Danio rerio A0A060Q6E4 R-DRE-8948231 https://reactome.org/PathwayBrowser/#/R-DRE-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Danio rerio A0A060Q6E4 R-DRE-8948232 https://reactome.org/PathwayBrowser/#/R-DRE-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Danio rerio A0A060Q6E4 R-DRE-8948234 https://reactome.org/PathwayBrowser/#/R-DRE-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Danio rerio A0A061ACK7 R-CEL-977324 https://reactome.org/PathwayBrowser/#/R-CEL-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Caenorhabditis elegans A0A061ACQ8 R-CEL-1169399 https://reactome.org/PathwayBrowser/#/R-CEL-1169399 Interaction of ISG15 with NEDD4 and inhibition of Ebola virus budding IEA Caenorhabditis elegans A0A061ACQ8 R-CEL-1973956 https://reactome.org/PathwayBrowser/#/R-CEL-1973956 NEDD4 binds ERBB4jmAcyt1s80 dimer IEA Caenorhabditis elegans A0A061ACQ8 R-CEL-1977296 https://reactome.org/PathwayBrowser/#/R-CEL-1977296 NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer IEA Caenorhabditis elegans A0A061ACQ8 R-CEL-2176491 https://reactome.org/PathwayBrowser/#/R-CEL-2176491 NEDD4L binds phosphorylated linker region of SMAD2/3 IEA Caenorhabditis elegans A0A061ACQ8 R-CEL-2176502 https://reactome.org/PathwayBrowser/#/R-CEL-2176502 NEDD4L ubiquitinates SMAD2/3 IEA Caenorhabditis elegans A0A061ACQ8 R-CEL-2682349 https://reactome.org/PathwayBrowser/#/R-CEL-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Caenorhabditis elegans A0A061ACQ8 R-CEL-6807134 https://reactome.org/PathwayBrowser/#/R-CEL-6807134 NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN IEA Caenorhabditis elegans A0A061ACQ8 R-CEL-983140 https://reactome.org/PathwayBrowser/#/R-CEL-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Caenorhabditis elegans A0A061ACQ8 R-CEL-983147 https://reactome.org/PathwayBrowser/#/R-CEL-983147 Release of E3 from polyubiquitinated substrate IEA Caenorhabditis elegans A0A061ACQ8 R-CEL-983156 https://reactome.org/PathwayBrowser/#/R-CEL-983156 Polyubiquitination of substrate IEA Caenorhabditis elegans A0A061ACQ8 R-CEL-983157 https://reactome.org/PathwayBrowser/#/R-CEL-983157 Interaction of E3 with substrate and E2-Ub complex IEA Caenorhabditis elegans A0A061ACY0 R-CEL-9647991 https://reactome.org/PathwayBrowser/#/R-CEL-9647991 Palmostatin B binds RAS depalmitoylases IEA Caenorhabditis elegans A0A061ACY0 R-CEL-9647994 https://reactome.org/PathwayBrowser/#/R-CEL-9647994 RAS proteins are depalmitoylated IEA Caenorhabditis elegans A0A061AD47 R-CEL-8865107 https://reactome.org/PathwayBrowser/#/R-CEL-8865107 MICAL1 produces NADP+, H2O2 IEA Caenorhabditis elegans A0A061AD52 R-CEL-6798747 https://reactome.org/PathwayBrowser/#/R-CEL-6798747 Exocytosis of tertiary granule membrane proteins IEA Caenorhabditis elegans A0A061AD52 R-CEL-6799350 https://reactome.org/PathwayBrowser/#/R-CEL-6799350 Exocytosis of specific granule membrane proteins IEA Caenorhabditis elegans A0A061AD52 R-CEL-9707505 https://reactome.org/PathwayBrowser/#/R-CEL-9707505 Hemes bind to CLEC1B dimer IEA Caenorhabditis elegans A0A061ADQ6 R-CEL-9018758 https://reactome.org/PathwayBrowser/#/R-CEL-9018758 RHOH binds effectors at the plasma membrane IEA Caenorhabditis elegans A0A061AE05 R-CEL-174389 https://reactome.org/PathwayBrowser/#/R-CEL-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Caenorhabditis elegans A0A061AE05 R-CEL-174392 https://reactome.org/PathwayBrowser/#/R-CEL-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Caenorhabditis elegans A0A068F9P7 R-DRE-5173005 https://reactome.org/PathwayBrowser/#/R-DRE-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Danio rerio A0A075B5J6 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5J6 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5J6 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5J6 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5J6 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5J6 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5J6 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5J6 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5J6 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5J6 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5J6 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5J6 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5J6 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5J6 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5J6 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5J6 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5J6 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5J6 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5J6 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5J6 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5J6 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5J6 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5J6 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5J6 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5J6 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5J6 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5J6 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5J6 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5J6 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5J6 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5J6 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5J6 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5J6 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5J6 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5J6 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5J6 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5J6 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5J6 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5J6 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5J6 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5J6 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5J6 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5J6 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5J6 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5J6 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5J6 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5J6 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5K3 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5K3 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5K3 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5K3 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5K3 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5K3 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5K3 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5K3 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5K3 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5K3 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5K3 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5K3 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5K3 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5K3 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5K3 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5K3 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5K3 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5K3 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5K3 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5K3 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5K3 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5K3 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5K3 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5K3 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5K3 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5K3 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5K3 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5K3 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5K3 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5K3 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5K3 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5K3 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5K3 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5K3 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5K3 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5K3 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5K3 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5K3 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5K3 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5K3 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5K3 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5K3 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5K3 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5K3 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5K3 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5K3 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5K3 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5K6 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5K6 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5K6 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5K6 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5K6 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5K6 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5K6 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5K6 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5K6 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5K6 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5K6 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5K6 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5K6 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5K6 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5K6 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5K6 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5K6 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5K6 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5K6 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5K6 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5K6 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5K6 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5K6 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5K6 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5K6 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5K6 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5K6 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5K6 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5K6 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5K6 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5K6 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5K6 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5K6 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5K6 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5K6 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5K6 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5K6 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5K6 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5K6 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5K6 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5K6 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5K6 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5K6 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5K6 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5K6 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5K6 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5K6 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5K8 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5K8 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5K8 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5K8 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5K8 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5K8 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5K8 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5K8 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5K8 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5K8 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5K8 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5K8 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5K8 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5K8 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5K8 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5K8 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5K8 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5K8 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5K8 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5K8 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5K8 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5K8 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5K8 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5K8 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5K8 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5K8 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5K8 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5K8 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5K8 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5K8 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5K8 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5K8 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5K8 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5K8 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5K8 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5K8 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5K8 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5K8 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5K8 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5K8 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5K8 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5K8 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5K8 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5K8 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5K8 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5K8 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5K8 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5M9 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5M9 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5M9 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5M9 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5M9 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5M9 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5M9 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5M9 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5M9 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5M9 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5M9 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5M9 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5M9 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5M9 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5M9 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5M9 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5M9 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5M9 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5M9 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5M9 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5M9 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5M9 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5M9 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5M9 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5M9 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5M9 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5M9 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5M9 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5M9 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5M9 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5M9 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5M9 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5M9 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5M9 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5M9 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5M9 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5M9 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5M9 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5M9 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5M9 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5M9 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5M9 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5M9 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5M9 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5M9 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5M9 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5M9 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5N0 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5N0 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5N0 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5N0 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5N0 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5N0 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5N0 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5N0 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5N0 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5N0 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5N0 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5N0 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5N0 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5N0 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5N0 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5N0 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5N0 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5N0 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5N0 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5N0 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5N0 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5N0 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5N0 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5N0 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5N0 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5N0 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5N0 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5N0 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5N0 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5N0 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5N0 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5N0 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5N0 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5N0 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5N0 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5N0 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5N0 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5N0 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5N0 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5N0 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5N0 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5N0 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5N0 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5N0 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5N0 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5N0 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5N0 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5P7 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5P7 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5P7 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5P7 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5P7 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5P7 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5P7 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5P7 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5P7 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5P7 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5P7 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5P7 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5P7 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5P7 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5P7 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5P7 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5P7 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5P7 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5P7 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5P7 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5P7 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5P7 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5P7 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5P7 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5P7 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5P7 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5P7 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5P7 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5P7 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5P7 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5P7 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5P7 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5P7 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5P7 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5P7 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5P7 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5P7 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5P7 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5P7 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5P7 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5P7 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5P7 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5P7 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5P7 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5P7 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5P7 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5P7 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5P7 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5P9 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5P9 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5P9 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5P9 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5P9 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5P9 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5P9 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5P9 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5P9 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5P9 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5P9 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5P9 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5P9 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5P9 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5P9 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5P9 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5P9 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5P9 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5P9 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5P9 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5P9 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5P9 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5P9 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5P9 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5P9 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5P9 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5P9 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5P9 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5P9 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5P9 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5P9 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5P9 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5P9 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5P9 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5P9 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5P9 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5P9 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5P9 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5P9 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5P9 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5P9 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5P9 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5P9 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5P9 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5P9 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5P9 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5P9 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5P9 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5Q0 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5Q0 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5Q0 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5Q0 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5Q0 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5Q0 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5Q0 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5Q0 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5Q0 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5Q0 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5Q0 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5Q0 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5Q0 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5Q0 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5Q0 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5Q0 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5Q0 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5Q0 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5Q0 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5Q0 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5Q0 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5Q0 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5Q0 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5Q0 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5Q0 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5Q0 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5Q0 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5Q0 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5Q0 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5Q0 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5Q0 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5Q0 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5Q0 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5Q0 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5Q0 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5Q0 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5Q0 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5Q0 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5Q0 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5Q0 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5Q0 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5Q0 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5Q0 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5Q0 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5Q0 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5Q0 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5Q0 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5Q0 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5Q2 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5Q2 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5Q2 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5Q2 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5Q2 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5Q2 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5Q2 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5Q2 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5Q2 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5Q2 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5Q2 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5Q2 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5Q2 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5Q2 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5Q2 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5Q2 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5Q2 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5Q2 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5Q2 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5Q2 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5Q2 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5Q2 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5Q2 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5Q2 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5Q2 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5Q2 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5Q2 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5Q2 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5Q2 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5Q2 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5Q2 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5Q2 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5Q2 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5Q2 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5Q2 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5Q2 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5Q2 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5Q2 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5Q2 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5Q2 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5Q2 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5Q2 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5Q2 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5Q2 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5Q2 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5Q2 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5Q2 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5Q2 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5Q4 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5Q4 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5Q4 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5Q4 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5Q4 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5Q4 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5Q4 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5Q4 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5Q4 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5Q4 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5Q4 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5Q4 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5Q4 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5Q4 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5Q4 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5Q4 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5Q4 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5Q4 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5Q4 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5Q4 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5Q4 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5Q4 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5Q4 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5Q4 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5Q4 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5Q4 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5Q4 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5Q4 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5Q4 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5Q4 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5Q4 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5Q4 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5Q4 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5Q4 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5Q4 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5Q4 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5Q4 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5Q4 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5Q4 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5Q4 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5Q4 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5Q4 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5Q4 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5Q4 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5Q4 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5Q4 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5Q4 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5Q4 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5Q6 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5Q6 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5Q6 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5Q6 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5Q6 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5Q6 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5Q6 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5Q6 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5Q6 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5Q6 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5Q6 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5Q6 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5Q6 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5Q6 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5Q6 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5Q6 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5Q6 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5Q6 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5Q6 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5Q6 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5Q6 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5Q6 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5Q6 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5Q6 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5Q6 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5Q6 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5Q6 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5Q6 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5Q6 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5Q6 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5Q6 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5Q6 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5Q6 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5Q6 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5Q6 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5Q6 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5Q6 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5Q6 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5Q6 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5Q6 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5Q6 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5Q6 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5Q6 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5Q6 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5Q6 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5Q6 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5Q6 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5Q6 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5Q9 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5Q9 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5Q9 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5Q9 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5Q9 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5Q9 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5Q9 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5Q9 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5Q9 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5Q9 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5Q9 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5Q9 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5Q9 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5Q9 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5Q9 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5Q9 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5Q9 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5Q9 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5Q9 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5Q9 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5Q9 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5Q9 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5Q9 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5Q9 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5Q9 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5Q9 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5Q9 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5Q9 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5Q9 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5Q9 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5Q9 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5Q9 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5Q9 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5Q9 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5Q9 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5Q9 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5Q9 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5Q9 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5Q9 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5Q9 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5Q9 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5Q9 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5Q9 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5Q9 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5Q9 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5Q9 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5Q9 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5Q9 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5R0 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5R0 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5R0 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5R0 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5R0 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5R0 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5R0 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5R0 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5R0 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5R0 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5R0 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5R0 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5R0 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5R0 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5R0 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5R0 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5R0 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5R0 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5R0 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5R0 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5R0 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5R0 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5R0 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5R0 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5R0 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5R0 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5R0 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5R0 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5R0 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5R0 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5R0 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5R0 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5R0 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5R0 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5R0 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5R0 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5R0 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5R0 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5R0 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5R0 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5R0 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5R0 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5R0 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5R0 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5R0 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5R0 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5R0 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5R0 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5R1 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5R1 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5R1 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5R1 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5R1 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5R1 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5R1 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5R1 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5R1 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5R1 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5R1 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5R1 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5R1 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5R1 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5R1 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5R1 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5R1 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5R1 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5R1 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5R1 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5R1 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5R1 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5R1 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5R1 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5R1 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5R1 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5R1 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5R1 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5R1 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5R1 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5R1 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5R1 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5R1 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5R1 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5R1 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5R1 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5R1 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5R1 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5R1 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5R1 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5R1 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5R1 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5R1 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5R1 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5R1 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5R1 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5R1 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5R1 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5R2 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5R2 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5R2 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5R2 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5R2 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5R2 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5R2 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5R2 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5R2 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5R2 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5R2 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5R2 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5R2 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5R2 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5R2 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5R2 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5R2 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5R2 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5R2 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5R2 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5R2 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5R2 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5R2 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5R2 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5R2 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5R2 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5R2 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5R2 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5R2 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5R2 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5R2 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5R2 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5R2 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5R2 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5R2 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5R2 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5R2 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5R2 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5R2 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5R2 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5R2 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5R2 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5R2 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5R2 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5R2 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5R2 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5R2 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5R2 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5R3 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5R3 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5R3 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5R3 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5R3 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5R3 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5R3 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5R3 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5R3 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5R3 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5R3 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5R3 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5R3 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5R3 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5R3 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5R3 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5R3 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5R3 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5R3 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5R3 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5R3 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5R3 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5R3 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5R3 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5R3 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5R3 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5R3 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5R3 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5R3 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5R3 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5R3 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5R3 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5R3 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5R3 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5R3 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5R3 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5R3 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5R3 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5R3 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5R3 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5R3 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5R3 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5R3 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5R3 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5R3 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5R3 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5R3 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5R3 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5S0 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5S0 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5S0 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5S0 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5S0 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5S0 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5S0 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5S0 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5S0 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5S0 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5S0 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5S0 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5S0 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5S0 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5S0 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5S0 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5S0 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5S0 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5S0 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5S0 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5S0 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5S0 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5S0 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5S0 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5S0 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5S0 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5S0 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5S0 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5S0 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5S0 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5S0 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5S0 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5S0 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5S0 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5S0 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5S0 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5S0 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5S0 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5S0 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5S0 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5S0 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5S0 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5S0 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5S0 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5S0 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5S0 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5S0 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5S0 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5S4 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5S4 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5S4 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5S4 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5S4 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5S4 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5S4 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5S4 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5S4 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5S4 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5S4 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5S4 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5S4 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5S4 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5S4 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5S4 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5S4 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5S4 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5S4 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5S4 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5S4 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5S4 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5S4 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5S4 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5S4 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5S4 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5S4 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5S4 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5S4 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5S4 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5S4 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5S4 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5S4 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5S4 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5S4 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5S4 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5S4 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5S4 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5S4 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5S4 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5S4 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5S4 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5S4 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5S4 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5S4 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5S4 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5S4 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5S4 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5S5 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5S5 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5S5 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5S5 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5S5 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5S5 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5S5 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5S5 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5S5 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5S5 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5S5 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5S5 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5S5 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5S5 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5S5 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5S5 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5S5 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5S5 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5S5 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5S5 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5S5 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5S5 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5S5 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5S5 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5S5 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5S5 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5S5 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5S5 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5S5 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5S5 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5S5 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5S5 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5S5 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5S5 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5S5 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5S5 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5S5 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5S5 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5S5 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5S5 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5S5 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5S5 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5S5 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5S5 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5S5 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5S5 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5S5 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5S5 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5S6 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5S6 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5S6 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5S6 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5S6 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5S6 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5S6 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5S6 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5S6 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5S6 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5S6 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5S6 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5S6 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5S6 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5S6 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5S6 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5S6 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5S6 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5S6 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5S6 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5S6 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5S6 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5S6 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5S6 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5S6 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5S6 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5S6 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5S6 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5S6 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5S6 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5S6 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5S6 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5S6 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5S6 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5S6 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5S6 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5S6 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5S6 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5S6 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5S6 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5S6 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5S6 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5S6 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5S6 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5S6 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5S6 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5S6 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5S6 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5T0 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5T0 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5T0 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5T0 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5T0 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5T0 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5T0 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5T0 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5T0 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5T0 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5T0 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5T0 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5T0 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5T0 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5T0 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5T0 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5T0 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5T0 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5T0 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5T0 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5T0 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5T0 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5T0 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5T0 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5T0 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5T0 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5T0 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5T0 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5T0 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5T0 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5T0 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5T0 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5T0 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5T0 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5T0 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5T0 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5T0 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5T0 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5T0 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5T0 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5T0 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5T0 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5T0 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5T0 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5T0 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5T0 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5T0 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5T0 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5T1 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5T1 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5T1 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5T1 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5T1 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5T1 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5T1 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5T1 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5T1 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5T1 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5T1 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5T1 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5T1 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5T1 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5T1 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5T1 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5T1 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5T1 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5T1 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5T1 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5T1 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5T1 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5T1 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5T1 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5T1 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5T1 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5T1 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5T1 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5T1 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5T1 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5T1 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5T1 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5T1 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5T1 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5T1 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5T1 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5T1 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5T1 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5T1 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5T1 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5T1 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5T1 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5T1 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5T1 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5T1 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5T1 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5T1 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5T1 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5T2 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5T2 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5T2 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5T2 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5T2 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5T2 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5T2 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5T2 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5T2 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5T2 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5T2 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5T2 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5T2 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5T2 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5T2 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5T2 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5T2 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5T2 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5T2 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5T2 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5T2 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5T2 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5T2 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5T2 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5T2 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5T2 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5T2 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5T2 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5T2 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5T2 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5T2 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5T2 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5T2 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5T2 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5T2 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5T2 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5T2 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5T2 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5T2 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5T2 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5T2 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5T2 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5T2 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5T2 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5T2 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5T2 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5T2 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5T2 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5T3 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5T3 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5T3 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5T3 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5T3 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5T3 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5T3 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5T3 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5T3 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5T3 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5T3 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5T3 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5T3 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5T3 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5T3 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5T3 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5T3 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5T3 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5T3 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5T3 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5T3 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5T3 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5T3 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5T3 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5T3 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5T3 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5T3 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5T3 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5T3 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5T3 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5T3 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5T3 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5T3 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5T3 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5T3 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5T3 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5T3 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5T3 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5T3 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5T3 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5T3 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5T3 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5T3 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5T3 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5T3 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5T3 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5T3 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5T3 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5W4 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5W4 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5W4 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5W4 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5W4 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5W4 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5W4 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5W4 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5W4 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5W4 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5W4 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5W4 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5W4 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5W4 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5W4 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5W4 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5W4 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5W4 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5W4 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5W4 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5W4 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5W4 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5W4 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5W4 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5W4 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5W4 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5W4 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5W4 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5W4 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5W4 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5W4 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5W4 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5W4 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5W4 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5W4 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5W4 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5W4 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5W4 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5W4 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5W4 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5W4 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5W4 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5W4 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5W4 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5W4 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5W4 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5W4 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5W4 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5X1 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5X1 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5X1 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5X1 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5X1 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5X1 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5X1 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5X1 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5X1 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5X1 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5X1 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5X1 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5X1 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5X1 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5X1 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5X1 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5X1 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5X1 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5X1 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5X1 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5X1 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5X1 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5X1 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5X1 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5X1 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5X1 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5X1 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5X1 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5X1 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5X1 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5X1 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5X1 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5X1 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5X1 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5X1 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5X1 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5X1 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5X1 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5X1 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5X1 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5X1 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5X1 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5X1 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5X1 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5X1 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5X1 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5X1 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5X1 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5X4 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5X4 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5X4 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5X4 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5X4 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5X4 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5X4 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5X4 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5X4 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5X4 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5X4 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5X4 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5X4 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5X4 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5X4 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5X4 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5X4 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5X4 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5X4 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5X4 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5X4 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5X4 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5X4 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5X4 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5X4 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5X4 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5X4 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5X4 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5X4 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5X4 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5X4 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5X4 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5X4 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5X4 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5X4 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5X4 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5X4 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5X4 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5X4 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5X4 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5X4 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5X4 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5X4 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5X4 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5X4 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5X4 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5X4 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5X4 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5X8 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5X8 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5X8 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5X8 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5X8 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5X8 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5X8 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5X8 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5X8 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5X8 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5X8 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5X8 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5X8 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5X8 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5X8 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5X8 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5X8 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5X8 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5X8 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5X8 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5X8 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5X8 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5X8 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5X8 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5X8 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5X8 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5X8 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5X8 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5X8 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5X8 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5X8 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5X8 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5X8 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5X8 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5X8 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5X8 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5X8 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5X8 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5X8 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5X8 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5X8 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5X8 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5X8 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5X8 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5X8 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5X8 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5X8 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5X8 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B5Y0 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B5Y0 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B5Y0 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B5Y0 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B5Y0 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B5Y0 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B5Y0 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B5Y0 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B5Y0 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B5Y0 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B5Y0 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B5Y0 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B5Y0 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B5Y0 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B5Y0 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B5Y0 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B5Y0 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B5Y0 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B5Y0 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B5Y0 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B5Y0 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B5Y0 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B5Y0 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B5Y0 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B5Y0 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B5Y0 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B5Y0 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B5Y0 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B5Y0 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B5Y0 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B5Y0 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B5Y0 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B5Y0 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B5Y0 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B5Y0 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B5Y0 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B5Y0 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B5Y0 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B5Y0 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B5Y0 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B5Y0 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B5Y0 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B5Y0 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B5Y0 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B5Y0 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B5Y0 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B5Y0 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B5Y0 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B653 R-MMU-198955 https://reactome.org/PathwayBrowser/#/R-MMU-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Mus musculus A0A075B653 R-MMU-202165 https://reactome.org/PathwayBrowser/#/R-MMU-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Mus musculus A0A075B653 R-MMU-202168 https://reactome.org/PathwayBrowser/#/R-MMU-202168 Phosphorylation of ZAP-70 by Lck IEA Mus musculus A0A075B653 R-MMU-202174 https://reactome.org/PathwayBrowser/#/R-MMU-202174 Activation of ZAP-70 IEA Mus musculus A0A075B653 R-MMU-202214 https://reactome.org/PathwayBrowser/#/R-MMU-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Mus musculus A0A075B653 R-MMU-202216 https://reactome.org/PathwayBrowser/#/R-MMU-202216 Phosphorylation of SLP-76 IEA Mus musculus A0A075B653 R-MMU-202233 https://reactome.org/PathwayBrowser/#/R-MMU-202233 Inactivation of Lck by Csk IEA Mus musculus A0A075B653 R-MMU-202245 https://reactome.org/PathwayBrowser/#/R-MMU-202245 Phosphorylation of TBSMs in LAT IEA Mus musculus A0A075B653 R-MMU-202248 https://reactome.org/PathwayBrowser/#/R-MMU-202248 Phosphorylation of PLC-gamma1 IEA Mus musculus A0A075B653 R-MMU-202291 https://reactome.org/PathwayBrowser/#/R-MMU-202291 Activation of Lck IEA Mus musculus A0A075B653 R-MMU-202307 https://reactome.org/PathwayBrowser/#/R-MMU-202307 Change of PKC theta conformation IEA Mus musculus A0A075B653 R-MMU-202344 https://reactome.org/PathwayBrowser/#/R-MMU-202344 Recruitment of ZAP-70 to phosphorylated ITAMs IEA Mus musculus A0A075B653 R-MMU-389758 https://reactome.org/PathwayBrowser/#/R-MMU-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Mus musculus A0A075B653 R-MMU-8850326 https://reactome.org/PathwayBrowser/#/R-MMU-8850326 TCR binds self-lipid-based antigen via CD1 IEA Mus musculus A0A075B653 R-MMU-8850356 https://reactome.org/PathwayBrowser/#/R-MMU-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Mus musculus A0A075B653 R-MMU-8852200 https://reactome.org/PathwayBrowser/#/R-MMU-8852200 Inactivation of LCK by PTPN22 IEA Mus musculus A0A075B653 R-MMU-8855381 https://reactome.org/PathwayBrowser/#/R-MMU-8855381 PTPN22 dephosphorylates ZAP70 IEA Mus musculus A0A075B662 R-MMU-198955 https://reactome.org/PathwayBrowser/#/R-MMU-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Mus musculus A0A075B662 R-MMU-202165 https://reactome.org/PathwayBrowser/#/R-MMU-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Mus musculus A0A075B662 R-MMU-202168 https://reactome.org/PathwayBrowser/#/R-MMU-202168 Phosphorylation of ZAP-70 by Lck IEA Mus musculus A0A075B662 R-MMU-202174 https://reactome.org/PathwayBrowser/#/R-MMU-202174 Activation of ZAP-70 IEA Mus musculus A0A075B662 R-MMU-202214 https://reactome.org/PathwayBrowser/#/R-MMU-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Mus musculus A0A075B662 R-MMU-202216 https://reactome.org/PathwayBrowser/#/R-MMU-202216 Phosphorylation of SLP-76 IEA Mus musculus A0A075B662 R-MMU-202233 https://reactome.org/PathwayBrowser/#/R-MMU-202233 Inactivation of Lck by Csk IEA Mus musculus A0A075B662 R-MMU-202245 https://reactome.org/PathwayBrowser/#/R-MMU-202245 Phosphorylation of TBSMs in LAT IEA Mus musculus A0A075B662 R-MMU-202248 https://reactome.org/PathwayBrowser/#/R-MMU-202248 Phosphorylation of PLC-gamma1 IEA Mus musculus A0A075B662 R-MMU-202291 https://reactome.org/PathwayBrowser/#/R-MMU-202291 Activation of Lck IEA Mus musculus A0A075B662 R-MMU-202307 https://reactome.org/PathwayBrowser/#/R-MMU-202307 Change of PKC theta conformation IEA Mus musculus A0A075B662 R-MMU-202344 https://reactome.org/PathwayBrowser/#/R-MMU-202344 Recruitment of ZAP-70 to phosphorylated ITAMs IEA Mus musculus A0A075B662 R-MMU-389758 https://reactome.org/PathwayBrowser/#/R-MMU-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Mus musculus A0A075B662 R-MMU-8850326 https://reactome.org/PathwayBrowser/#/R-MMU-8850326 TCR binds self-lipid-based antigen via CD1 IEA Mus musculus A0A075B662 R-MMU-8850356 https://reactome.org/PathwayBrowser/#/R-MMU-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Mus musculus A0A075B662 R-MMU-8852200 https://reactome.org/PathwayBrowser/#/R-MMU-8852200 Inactivation of LCK by PTPN22 IEA Mus musculus A0A075B662 R-MMU-8855381 https://reactome.org/PathwayBrowser/#/R-MMU-8855381 PTPN22 dephosphorylates ZAP70 IEA Mus musculus A0A075B693 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A075B693 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A075B693 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A075B693 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A075B693 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A075B693 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A075B693 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A075B693 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A075B693 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A075B693 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A075B693 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A075B693 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A075B693 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A075B693 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A075B693 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A075B693 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A075B693 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A075B693 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A075B693 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A075B693 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A075B693 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A075B693 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A075B693 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A075B693 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A075B693 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A075B693 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A075B693 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A075B693 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A075B693 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A075B693 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A075B693 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A075B693 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A075B693 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A075B693 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A075B693 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A075B693 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A075B693 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A075B693 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A075B693 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A075B693 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A075B693 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A075B693 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A075B693 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A075B693 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A075B693 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A075B693 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A075B693 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A075B693 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A075B6P5 R-HSA-1112666 https://reactome.org/PathwayBrowser/#/R-HSA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate TAS Homo sapiens A0A075B6P5 R-HSA-166753 https://reactome.org/PathwayBrowser/#/R-HSA-166753 Conversion of C4 into C4a and C4b TAS Homo sapiens A0A075B6P5 R-HSA-166792 https://reactome.org/PathwayBrowser/#/R-HSA-166792 Conversion of C2 into C2a and C2b TAS Homo sapiens A0A075B6P5 R-HSA-173626 https://reactome.org/PathwayBrowser/#/R-HSA-173626 Activation of C1r TAS Homo sapiens A0A075B6P5 R-HSA-173631 https://reactome.org/PathwayBrowser/#/R-HSA-173631 Activation of C1s TAS Homo sapiens A0A075B6P5 R-HSA-1861621 https://reactome.org/PathwayBrowser/#/R-HSA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag TAS Homo sapiens A0A075B6P5 R-HSA-199161 https://reactome.org/PathwayBrowser/#/R-HSA-199161 Fc gamma receptors interact with antigen-bound IgG TAS Homo sapiens A0A075B6P5 R-HSA-2029268 https://reactome.org/PathwayBrowser/#/R-HSA-2029268 Phosphorylation and activation of PLCG TAS Homo sapiens A0A075B6P5 R-HSA-2029270 https://reactome.org/PathwayBrowser/#/R-HSA-2029270 Recruitment of PLCgamma to membrane TAS Homo sapiens A0A075B6P5 R-HSA-2029271 https://reactome.org/PathwayBrowser/#/R-HSA-2029271 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens A0A075B6P5 R-HSA-2029272 https://reactome.org/PathwayBrowser/#/R-HSA-2029272 Release of PLCG from FCGR TAS Homo sapiens A0A075B6P5 R-HSA-2029273 https://reactome.org/PathwayBrowser/#/R-HSA-2029273 PI3K binds to p-6Y-SYK TAS Homo sapiens A0A075B6P5 R-HSA-2029449 https://reactome.org/PathwayBrowser/#/R-HSA-2029449 Phosphorylation of SYK by Src kinases IEA Homo sapiens A0A075B6P5 R-HSA-2029451 https://reactome.org/PathwayBrowser/#/R-HSA-2029451 Activation of RAC1 by VAV TAS Homo sapiens A0A075B6P5 R-HSA-2029452 https://reactome.org/PathwayBrowser/#/R-HSA-2029452 Recruitment of SYK to phosphorylated ITAMs TAS Homo sapiens A0A075B6P5 R-HSA-2029453 https://reactome.org/PathwayBrowser/#/R-HSA-2029453 Phosphorylation of VAV TAS Homo sapiens A0A075B6P5 R-HSA-2029455 https://reactome.org/PathwayBrowser/#/R-HSA-2029455 Cross-linking of FCGRIA with IgG-coated Ag TAS Homo sapiens A0A075B6P5 R-HSA-2029457 https://reactome.org/PathwayBrowser/#/R-HSA-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag TAS Homo sapiens A0A075B6P5 R-HSA-2029458 https://reactome.org/PathwayBrowser/#/R-HSA-2029458 Recruitment of VAV1 to p-6Y-SYK TAS Homo sapiens A0A075B6P5 R-HSA-2029459 https://reactome.org/PathwayBrowser/#/R-HSA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts TAS Homo sapiens A0A075B6P5 R-HSA-2029467 https://reactome.org/PathwayBrowser/#/R-HSA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO TAS Homo sapiens A0A075B6P5 R-HSA-2029476 https://reactome.org/PathwayBrowser/#/R-HSA-2029476 Role of myosins in phagosome formation TAS Homo sapiens A0A075B6P5 R-HSA-2197697 https://reactome.org/PathwayBrowser/#/R-HSA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR TAS Homo sapiens A0A075B6P5 R-HSA-2203516 https://reactome.org/PathwayBrowser/#/R-HSA-2203516 Alpha-1-Microglobulin is cleaved TAS Homo sapiens A0A075B6P5 R-HSA-2454192 https://reactome.org/PathwayBrowser/#/R-HSA-2454192 Allergen dependent IgE bound FCERI aggregation TAS Homo sapiens A0A075B6P5 R-HSA-2454208 https://reactome.org/PathwayBrowser/#/R-HSA-2454208 Phosphorylation of beta and gamma subunits by LYN TAS Homo sapiens A0A075B6P5 R-HSA-2454239 https://reactome.org/PathwayBrowser/#/R-HSA-2454239 Phosphorylation of SYK IEA Homo sapiens A0A075B6P5 R-HSA-2454240 https://reactome.org/PathwayBrowser/#/R-HSA-2454240 Recruitment of SYK to p-FCERI gamma subunit TAS Homo sapiens A0A075B6P5 R-HSA-2730833 https://reactome.org/PathwayBrowser/#/R-HSA-2730833 Phosphorylation of TEC kinases by p-SYK TAS Homo sapiens A0A075B6P5 R-HSA-2730843 https://reactome.org/PathwayBrowser/#/R-HSA-2730843 Phosphorylation of LAT by p-SYK TAS Homo sapiens A0A075B6P5 R-HSA-2730851 https://reactome.org/PathwayBrowser/#/R-HSA-2730851 Phosphorylation of SLP-76 by p-SYK TAS Homo sapiens A0A075B6P5 R-HSA-2730860 https://reactome.org/PathwayBrowser/#/R-HSA-2730860 Phosphorylation of GAB2 by SYK/FYN IEA Homo sapiens A0A075B6P5 R-HSA-2730882 https://reactome.org/PathwayBrowser/#/R-HSA-2730882 Phosphorylation of PKC-theta TAS Homo sapiens A0A075B6P5 R-HSA-2730884 https://reactome.org/PathwayBrowser/#/R-HSA-2730884 Phosphorylation of NTAL by p-SYK/Lyn TAS Homo sapiens A0A075B6P5 R-HSA-2730886 https://reactome.org/PathwayBrowser/#/R-HSA-2730886 Phosphorylation of SHC by SYK kinase TAS Homo sapiens A0A075B6P5 R-HSA-2730888 https://reactome.org/PathwayBrowser/#/R-HSA-2730888 Phosphorylation of PLC-gamma IEA Homo sapiens A0A075B6P5 R-HSA-5690701 https://reactome.org/PathwayBrowser/#/R-HSA-5690701 SHP1 binds p-CD22 TAS Homo sapiens A0A075B6P5 R-HSA-5690702 https://reactome.org/PathwayBrowser/#/R-HSA-5690702 LYN phosphorylates CD22 TAS Homo sapiens A0A075B6P5 R-HSA-5690740 https://reactome.org/PathwayBrowser/#/R-HSA-5690740 CD22 binds B-cell receptor TAS Homo sapiens A0A075B6P5 R-HSA-8852266 https://reactome.org/PathwayBrowser/#/R-HSA-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s TAS Homo sapiens A0A075B6P5 R-HSA-8852481 https://reactome.org/PathwayBrowser/#/R-HSA-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates TAS Homo sapiens A0A075B6P5 R-HSA-8858428 https://reactome.org/PathwayBrowser/#/R-HSA-8858428 FCAMR binds IgA TAS Homo sapiens A0A075B6P5 R-HSA-9021306 https://reactome.org/PathwayBrowser/#/R-HSA-9021306 C1-Inh binds and inactivates C1r, C1s TAS Homo sapiens A0A075B6P5 R-HSA-9606151 https://reactome.org/PathwayBrowser/#/R-HSA-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 TAS Homo sapiens A0A075B6P5 R-HSA-9606159 https://reactome.org/PathwayBrowser/#/R-HSA-9606159 BTK autophosphorylates IEA Homo sapiens A0A075B6P5 R-HSA-9606162 https://reactome.org/PathwayBrowser/#/R-HSA-9606162 Phosphorylated BTK phosphorylates PLCG2 IEA Homo sapiens A0A075B6P5 R-HSA-9606163 https://reactome.org/PathwayBrowser/#/R-HSA-9606163 p-SYK and LYN phosphorylate BTK IEA Homo sapiens A0A075B6P5 R-HSA-9664261 https://reactome.org/PathwayBrowser/#/R-HSA-9664261 Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK TAS Homo sapiens A0A075B6P5 R-HSA-9664268 https://reactome.org/PathwayBrowser/#/R-HSA-9664268 Opsonized leishmania amastigote binds FCGR3 TAS Homo sapiens A0A075B6P5 R-HSA-9664270 https://reactome.org/PathwayBrowser/#/R-HSA-9664270 Recruitment of PLCgamma to membrane due to FCGR3A effect TAS Homo sapiens A0A075B6P5 R-HSA-9664271 https://reactome.org/PathwayBrowser/#/R-HSA-9664271 Release of PLCG from FCGR3A TAS Homo sapiens A0A075B6P5 R-HSA-9664273 https://reactome.org/PathwayBrowser/#/R-HSA-9664273 SYK binds IgG:Lma antigens:FCGR3A:p-CD3 dimers TAS Homo sapiens A0A075B6P5 R-HSA-9664275 https://reactome.org/PathwayBrowser/#/R-HSA-9664275 Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers TAS Homo sapiens A0A075B6P5 R-HSA-9664278 https://reactome.org/PathwayBrowser/#/R-HSA-9664278 Phosphorylation and activation of PLCG due to FCGR3A effect TAS Homo sapiens A0A075B6P5 R-HSA-9664285 https://reactome.org/PathwayBrowser/#/R-HSA-9664285 IgG binds the surface of the amastigote form of Leishmania TAS Homo sapiens A0A075B6P5 R-HSA-9664397 https://reactome.org/PathwayBrowser/#/R-HSA-9664397 IgG binds LPG1G2 in the amastigote form of Leishmania IEA Homo sapiens A0A075B6P5 R-HSA-9664406 https://reactome.org/PathwayBrowser/#/R-HSA-9664406 IgG:Lma antigens binds FCGR3A:CD3 dimers TAS Homo sapiens A0A075B6P5 R-HSA-9666425 https://reactome.org/PathwayBrowser/#/R-HSA-9666425 p-6Y-SYK phosphorylates VAV1,2,3 TAS Homo sapiens A0A075B6P5 R-HSA-9666426 https://reactome.org/PathwayBrowser/#/R-HSA-9666426 CRKII:DOCK180:ELMO binds FCGR3A TAS Homo sapiens A0A075B6P5 R-HSA-9666428 https://reactome.org/PathwayBrowser/#/R-HSA-9666428 DOCK180 exchanges GTP for GDP on RAC1:GDP TAS Homo sapiens A0A075B6P5 R-HSA-9666430 https://reactome.org/PathwayBrowser/#/R-HSA-9666430 p-VAV1,2,3 exchanges GTP for GDP on RAC1:GDP TAS Homo sapiens A0A075B6P5 R-HSA-9666433 https://reactome.org/PathwayBrowser/#/R-HSA-9666433 IgG binds the surface of the amastigote form of Leishmania TAS Homo sapiens A0A075B6P5 R-HSA-9666435 https://reactome.org/PathwayBrowser/#/R-HSA-9666435 VAV1,2,3:PI(3,4,5)P3 binds p-6Y-SYK TAS Homo sapiens A0A075B6P5 R-HSA-9666458 https://reactome.org/PathwayBrowser/#/R-HSA-9666458 IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole TAS Homo sapiens A0A075B6P5 R-HSA-9691421 https://reactome.org/PathwayBrowser/#/R-HSA-9691421 BTK binds BTK inhibitors TAS Homo sapiens A0A075B6P5 R-HSA-9724685 https://reactome.org/PathwayBrowser/#/R-HSA-9724685 IgE binds omalizumab TAS Homo sapiens A0A075B6P5 R-HSA-9725206 https://reactome.org/PathwayBrowser/#/R-HSA-9725206 IgE binds FCERI TAS Homo sapiens A0A075B6P5 R-HSA-983696 https://reactome.org/PathwayBrowser/#/R-HSA-983696 The Immunoglobulin of the BCR binds antigen TAS Homo sapiens A0A075B6P5 R-HSA-983700 https://reactome.org/PathwayBrowser/#/R-HSA-983700 SYK binds the activated BCR TAS Homo sapiens A0A075B6P5 R-HSA-983703 https://reactome.org/PathwayBrowser/#/R-HSA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) TAS Homo sapiens A0A075B6P5 R-HSA-983707 https://reactome.org/PathwayBrowser/#/R-HSA-983707 SYK autophosphorylates at the activated BCR TAS Homo sapiens A0A075B6P5 R-HSA-983709 https://reactome.org/PathwayBrowser/#/R-HSA-983709 LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B) IEA Homo sapiens A0A075B6S6 R-HSA-1112666 https://reactome.org/PathwayBrowser/#/R-HSA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate TAS Homo sapiens A0A075B6S6 R-HSA-166753 https://reactome.org/PathwayBrowser/#/R-HSA-166753 Conversion of C4 into C4a and C4b TAS Homo sapiens A0A075B6S6 R-HSA-166792 https://reactome.org/PathwayBrowser/#/R-HSA-166792 Conversion of C2 into C2a and C2b TAS Homo sapiens A0A075B6S6 R-HSA-173626 https://reactome.org/PathwayBrowser/#/R-HSA-173626 Activation of C1r TAS Homo sapiens A0A075B6S6 R-HSA-173631 https://reactome.org/PathwayBrowser/#/R-HSA-173631 Activation of C1s TAS Homo sapiens A0A075B6S6 R-HSA-1861621 https://reactome.org/PathwayBrowser/#/R-HSA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag TAS Homo sapiens A0A075B6S6 R-HSA-199161 https://reactome.org/PathwayBrowser/#/R-HSA-199161 Fc gamma receptors interact with antigen-bound IgG TAS Homo sapiens A0A075B6S6 R-HSA-2029268 https://reactome.org/PathwayBrowser/#/R-HSA-2029268 Phosphorylation and activation of PLCG TAS Homo sapiens A0A075B6S6 R-HSA-2029270 https://reactome.org/PathwayBrowser/#/R-HSA-2029270 Recruitment of PLCgamma to membrane TAS Homo sapiens A0A075B6S6 R-HSA-2029271 https://reactome.org/PathwayBrowser/#/R-HSA-2029271 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens A0A075B6S6 R-HSA-2029272 https://reactome.org/PathwayBrowser/#/R-HSA-2029272 Release of PLCG from FCGR TAS Homo sapiens A0A075B6S6 R-HSA-2029273 https://reactome.org/PathwayBrowser/#/R-HSA-2029273 PI3K binds to p-6Y-SYK TAS Homo sapiens A0A075B6S6 R-HSA-2029449 https://reactome.org/PathwayBrowser/#/R-HSA-2029449 Phosphorylation of SYK by Src kinases IEA Homo sapiens A0A075B6S6 R-HSA-2029451 https://reactome.org/PathwayBrowser/#/R-HSA-2029451 Activation of RAC1 by VAV TAS Homo sapiens A0A075B6S6 R-HSA-2029452 https://reactome.org/PathwayBrowser/#/R-HSA-2029452 Recruitment of SYK to phosphorylated ITAMs TAS Homo sapiens A0A075B6S6 R-HSA-2029453 https://reactome.org/PathwayBrowser/#/R-HSA-2029453 Phosphorylation of VAV TAS Homo sapiens A0A075B6S6 R-HSA-2029455 https://reactome.org/PathwayBrowser/#/R-HSA-2029455 Cross-linking of FCGRIA with IgG-coated Ag TAS Homo sapiens A0A075B6S6 R-HSA-2029457 https://reactome.org/PathwayBrowser/#/R-HSA-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag TAS Homo sapiens A0A075B6S6 R-HSA-2029458 https://reactome.org/PathwayBrowser/#/R-HSA-2029458 Recruitment of VAV1 to p-6Y-SYK TAS Homo sapiens A0A075B6S6 R-HSA-2029459 https://reactome.org/PathwayBrowser/#/R-HSA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts TAS Homo sapiens A0A075B6S6 R-HSA-2029467 https://reactome.org/PathwayBrowser/#/R-HSA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO TAS Homo sapiens A0A075B6S6 R-HSA-2029476 https://reactome.org/PathwayBrowser/#/R-HSA-2029476 Role of myosins in phagosome formation TAS Homo sapiens A0A075B6S6 R-HSA-2197697 https://reactome.org/PathwayBrowser/#/R-HSA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR TAS Homo sapiens A0A075B6S6 R-HSA-2203516 https://reactome.org/PathwayBrowser/#/R-HSA-2203516 Alpha-1-Microglobulin is cleaved TAS Homo sapiens A0A075B6S6 R-HSA-2454192 https://reactome.org/PathwayBrowser/#/R-HSA-2454192 Allergen dependent IgE bound FCERI aggregation TAS Homo sapiens A0A075B6S6 R-HSA-2454208 https://reactome.org/PathwayBrowser/#/R-HSA-2454208 Phosphorylation of beta and gamma subunits by LYN TAS Homo sapiens A0A075B6S6 R-HSA-2454239 https://reactome.org/PathwayBrowser/#/R-HSA-2454239 Phosphorylation of SYK IEA Homo sapiens A0A075B6S6 R-HSA-2454240 https://reactome.org/PathwayBrowser/#/R-HSA-2454240 Recruitment of SYK to p-FCERI gamma subunit TAS Homo sapiens A0A075B6S6 R-HSA-2730833 https://reactome.org/PathwayBrowser/#/R-HSA-2730833 Phosphorylation of TEC kinases by p-SYK TAS Homo sapiens A0A075B6S6 R-HSA-2730843 https://reactome.org/PathwayBrowser/#/R-HSA-2730843 Phosphorylation of LAT by p-SYK TAS Homo sapiens A0A075B6S6 R-HSA-2730851 https://reactome.org/PathwayBrowser/#/R-HSA-2730851 Phosphorylation of SLP-76 by p-SYK TAS Homo sapiens A0A075B6S6 R-HSA-2730860 https://reactome.org/PathwayBrowser/#/R-HSA-2730860 Phosphorylation of GAB2 by SYK/FYN IEA Homo sapiens A0A075B6S6 R-HSA-2730882 https://reactome.org/PathwayBrowser/#/R-HSA-2730882 Phosphorylation of PKC-theta TAS Homo sapiens A0A075B6S6 R-HSA-2730884 https://reactome.org/PathwayBrowser/#/R-HSA-2730884 Phosphorylation of NTAL by p-SYK/Lyn TAS Homo sapiens A0A075B6S6 R-HSA-2730886 https://reactome.org/PathwayBrowser/#/R-HSA-2730886 Phosphorylation of SHC by SYK kinase TAS Homo sapiens A0A075B6S6 R-HSA-2730888 https://reactome.org/PathwayBrowser/#/R-HSA-2730888 Phosphorylation of PLC-gamma IEA Homo sapiens A0A075B6S6 R-HSA-5690701 https://reactome.org/PathwayBrowser/#/R-HSA-5690701 SHP1 binds p-CD22 TAS Homo sapiens A0A075B6S6 R-HSA-5690702 https://reactome.org/PathwayBrowser/#/R-HSA-5690702 LYN phosphorylates CD22 TAS Homo sapiens A0A075B6S6 R-HSA-5690740 https://reactome.org/PathwayBrowser/#/R-HSA-5690740 CD22 binds B-cell receptor TAS Homo sapiens A0A075B6S6 R-HSA-8852266 https://reactome.org/PathwayBrowser/#/R-HSA-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s TAS Homo sapiens A0A075B6S6 R-HSA-8852481 https://reactome.org/PathwayBrowser/#/R-HSA-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates TAS Homo sapiens A0A075B6S6 R-HSA-8858428 https://reactome.org/PathwayBrowser/#/R-HSA-8858428 FCAMR binds IgA TAS Homo sapiens A0A075B6S6 R-HSA-9021306 https://reactome.org/PathwayBrowser/#/R-HSA-9021306 C1-Inh binds and inactivates C1r, C1s TAS Homo sapiens A0A075B6S6 R-HSA-9606151 https://reactome.org/PathwayBrowser/#/R-HSA-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 TAS Homo sapiens A0A075B6S6 R-HSA-9606159 https://reactome.org/PathwayBrowser/#/R-HSA-9606159 BTK autophosphorylates IEA Homo sapiens A0A075B6S6 R-HSA-9606162 https://reactome.org/PathwayBrowser/#/R-HSA-9606162 Phosphorylated BTK phosphorylates PLCG2 IEA Homo sapiens A0A075B6S6 R-HSA-9606163 https://reactome.org/PathwayBrowser/#/R-HSA-9606163 p-SYK and LYN phosphorylate BTK IEA Homo sapiens A0A075B6S6 R-HSA-9664261 https://reactome.org/PathwayBrowser/#/R-HSA-9664261 Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK TAS Homo sapiens A0A075B6S6 R-HSA-9664268 https://reactome.org/PathwayBrowser/#/R-HSA-9664268 Opsonized leishmania amastigote binds FCGR3 TAS Homo sapiens A0A075B6S6 R-HSA-9664270 https://reactome.org/PathwayBrowser/#/R-HSA-9664270 Recruitment of PLCgamma to membrane due to FCGR3A effect TAS Homo sapiens A0A075B6S6 R-HSA-9664271 https://reactome.org/PathwayBrowser/#/R-HSA-9664271 Release of PLCG from FCGR3A TAS Homo sapiens A0A075B6S6 R-HSA-9664273 https://reactome.org/PathwayBrowser/#/R-HSA-9664273 SYK binds IgG:Lma antigens:FCGR3A:p-CD3 dimers TAS Homo sapiens A0A075B6S6 R-HSA-9664275 https://reactome.org/PathwayBrowser/#/R-HSA-9664275 Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers TAS Homo sapiens A0A075B6S6 R-HSA-9664278 https://reactome.org/PathwayBrowser/#/R-HSA-9664278 Phosphorylation and activation of PLCG due to FCGR3A effect TAS Homo sapiens A0A075B6S6 R-HSA-9664285 https://reactome.org/PathwayBrowser/#/R-HSA-9664285 IgG binds the surface of the amastigote form of Leishmania TAS Homo sapiens A0A075B6S6 R-HSA-9664397 https://reactome.org/PathwayBrowser/#/R-HSA-9664397 IgG binds LPG1G2 in the amastigote form of Leishmania IEA Homo sapiens A0A075B6S6 R-HSA-9664406 https://reactome.org/PathwayBrowser/#/R-HSA-9664406 IgG:Lma antigens binds FCGR3A:CD3 dimers TAS Homo sapiens A0A075B6S6 R-HSA-9666425 https://reactome.org/PathwayBrowser/#/R-HSA-9666425 p-6Y-SYK phosphorylates VAV1,2,3 TAS Homo sapiens A0A075B6S6 R-HSA-9666426 https://reactome.org/PathwayBrowser/#/R-HSA-9666426 CRKII:DOCK180:ELMO binds FCGR3A TAS Homo sapiens A0A075B6S6 R-HSA-9666428 https://reactome.org/PathwayBrowser/#/R-HSA-9666428 DOCK180 exchanges GTP for GDP on RAC1:GDP TAS Homo sapiens A0A075B6S6 R-HSA-9666430 https://reactome.org/PathwayBrowser/#/R-HSA-9666430 p-VAV1,2,3 exchanges GTP for GDP on RAC1:GDP TAS Homo sapiens A0A075B6S6 R-HSA-9666433 https://reactome.org/PathwayBrowser/#/R-HSA-9666433 IgG binds the surface of the amastigote form of Leishmania TAS Homo sapiens A0A075B6S6 R-HSA-9666435 https://reactome.org/PathwayBrowser/#/R-HSA-9666435 VAV1,2,3:PI(3,4,5)P3 binds p-6Y-SYK TAS Homo sapiens A0A075B6S6 R-HSA-9666458 https://reactome.org/PathwayBrowser/#/R-HSA-9666458 IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole TAS Homo sapiens A0A075B6S6 R-HSA-9691421 https://reactome.org/PathwayBrowser/#/R-HSA-9691421 BTK binds BTK inhibitors TAS Homo sapiens A0A075B6S6 R-HSA-9724685 https://reactome.org/PathwayBrowser/#/R-HSA-9724685 IgE binds omalizumab TAS Homo sapiens A0A075B6S6 R-HSA-9725206 https://reactome.org/PathwayBrowser/#/R-HSA-9725206 IgE binds FCERI TAS Homo sapiens A0A075B6S6 R-HSA-983696 https://reactome.org/PathwayBrowser/#/R-HSA-983696 The Immunoglobulin of the BCR binds antigen TAS Homo sapiens A0A075B6S6 R-HSA-983700 https://reactome.org/PathwayBrowser/#/R-HSA-983700 SYK binds the activated BCR TAS Homo sapiens A0A075B6S6 R-HSA-983703 https://reactome.org/PathwayBrowser/#/R-HSA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) TAS Homo sapiens A0A075B6S6 R-HSA-983707 https://reactome.org/PathwayBrowser/#/R-HSA-983707 SYK autophosphorylates at the activated BCR TAS Homo sapiens A0A075B6S6 R-HSA-983709 https://reactome.org/PathwayBrowser/#/R-HSA-983709 LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B) IEA Homo sapiens A0A075B7I6 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A075B7I6 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A075B7I6 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A075B7I6 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A075B7I6 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A075B7I6 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A075B7I6 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A075B7I6 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A075B7I6 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A075B7I6 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A075B7I6 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A075B7I6 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A075B7I6 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A075B7I6 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A075B7I6 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A075B7I6 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A075B7I6 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A075B7I6 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A075B7I6 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A075B7I6 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A075B7I6 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A075B7I6 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A075B7I6 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A075B7I6 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A075B7I6 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A075B7I6 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A075B7I6 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A075B7I6 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A075B7I6 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A075B7I6 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A075B7I6 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A075B7I6 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A075B7I6 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A075B7I6 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A075B7I6 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A075B7I6 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A075B7I6 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A075B7I6 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A075B7I6 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A075B7I6 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A075B7I6 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A075B7I6 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A075B7I6 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A075B7I6 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A075B7I6 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A075B7I6 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A075B7I6 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A075BR52 R-DRE-9842833 https://reactome.org/PathwayBrowser/#/R-DRE-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Danio rerio A0A076KXE7 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A076KXE7 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A076V5Y0 R-SSC-8940388 https://reactome.org/PathwayBrowser/#/R-SSC-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Sus scrofa A0A078BQJ0 R-CEL-210420 https://reactome.org/PathwayBrowser/#/R-CEL-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Caenorhabditis elegans A0A078BQJ0 R-CEL-265645 https://reactome.org/PathwayBrowser/#/R-CEL-265645 Calcium Influx through Voltage-gated Calcium Channels IEA Caenorhabditis elegans A0A078BQJ0 R-CEL-5577213 https://reactome.org/PathwayBrowser/#/R-CEL-5577213 LTCC multimer transports Ca2+ from extracellular region to cytosol IEA Caenorhabditis elegans A0A078BQJ0 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans A0A078BQP2 R-CEL-74885 https://reactome.org/PathwayBrowser/#/R-CEL-74885 GUCYs converts GTP to cGMP IEA Caenorhabditis elegans A0A078BS51 R-CEL-8956365 https://reactome.org/PathwayBrowser/#/R-CEL-8956365 ZBED1 (DREF) SUMOylates CHD3 with SUMO1 IEA Caenorhabditis elegans A0A087WNP5 R-MMU-975040 https://reactome.org/PathwayBrowser/#/R-MMU-975040 KRAB-ZNF / KAP Interaction IEA Mus musculus A0A087WNP5 R-MMU-9842833 https://reactome.org/PathwayBrowser/#/R-MMU-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Mus musculus A0A087WPC3 R-MMU-211873 https://reactome.org/PathwayBrowser/#/R-MMU-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Mus musculus A0A087WPC3 R-MMU-211924 https://reactome.org/PathwayBrowser/#/R-MMU-211924 CYP4B1 12-hydroxylates ARA IEA Mus musculus A0A087WPC3 R-MMU-211962 https://reactome.org/PathwayBrowser/#/R-MMU-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Mus musculus A0A087WPC3 R-MMU-215526 https://reactome.org/PathwayBrowser/#/R-MMU-215526 CYP4F3 20-hydroxylates LTB4 IEA Mus musculus A0A087WPC3 R-MMU-2161745 https://reactome.org/PathwayBrowser/#/R-MMU-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Mus musculus A0A087WPC3 R-MMU-2161792 https://reactome.org/PathwayBrowser/#/R-MMU-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Mus musculus A0A087WPC3 R-MMU-76466 https://reactome.org/PathwayBrowser/#/R-MMU-76466 CYP4A11 12-hydroxylates DDCX IEA Mus musculus A0A087WPF7 R-MMU-8937989 https://reactome.org/PathwayBrowser/#/R-MMU-8937989 RUNX1 binds PRC1 complexes IEA Mus musculus A0A087WPH4 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A087WPN2 R-MMU-975040 https://reactome.org/PathwayBrowser/#/R-MMU-975040 KRAB-ZNF / KAP Interaction IEA Mus musculus A0A087WPN2 R-MMU-9842833 https://reactome.org/PathwayBrowser/#/R-MMU-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Mus musculus A0A087WPN7 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A087WPN7 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A087WPN7 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A087WPN7 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A087WPN7 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A087WPN7 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A087WPN7 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A087WPN7 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A087WPN7 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A087WPN7 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A087WPN7 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A087WPN7 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A087WPN7 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A087WPN7 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A087WPN7 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A087WPN7 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A087WPN7 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A087WPN7 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A087WPN7 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A087WPN7 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A087WPN7 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A087WPN7 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A087WPN7 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A087WPN7 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A087WPN7 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A087WPN7 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A087WPN7 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A087WPN7 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A087WPN7 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A087WPN7 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A087WPN7 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A087WPN7 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A087WPN7 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A087WPN7 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A087WPN7 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A087WPN7 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A087WPN7 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A087WPN7 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A087WPN7 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A087WPN7 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A087WPN7 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A087WPN7 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A087WPN7 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A087WPN7 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A087WPN7 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A087WPN7 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A087WPN7 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A087WPN7 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A087WQI7 R-MMU-975040 https://reactome.org/PathwayBrowser/#/R-MMU-975040 KRAB-ZNF / KAP Interaction IEA Mus musculus A0A087WQI7 R-MMU-9842833 https://reactome.org/PathwayBrowser/#/R-MMU-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Mus musculus A0A087WQL6 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A087WRR7 R-MMU-975040 https://reactome.org/PathwayBrowser/#/R-MMU-975040 KRAB-ZNF / KAP Interaction IEA Mus musculus A0A087WS15 R-MMU-211873 https://reactome.org/PathwayBrowser/#/R-MMU-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Mus musculus A0A087WS15 R-MMU-211924 https://reactome.org/PathwayBrowser/#/R-MMU-211924 CYP4B1 12-hydroxylates ARA IEA Mus musculus A0A087WS15 R-MMU-211962 https://reactome.org/PathwayBrowser/#/R-MMU-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Mus musculus A0A087WS15 R-MMU-215526 https://reactome.org/PathwayBrowser/#/R-MMU-215526 CYP4F3 20-hydroxylates LTB4 IEA Mus musculus A0A087WS15 R-MMU-2161745 https://reactome.org/PathwayBrowser/#/R-MMU-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Mus musculus A0A087WS15 R-MMU-2161792 https://reactome.org/PathwayBrowser/#/R-MMU-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Mus musculus A0A087WS15 R-MMU-76466 https://reactome.org/PathwayBrowser/#/R-MMU-76466 CYP4A11 12-hydroxylates DDCX IEA Mus musculus A0A087WS64 R-MMU-975040 https://reactome.org/PathwayBrowser/#/R-MMU-975040 KRAB-ZNF / KAP Interaction IEA Mus musculus A0A096LNF2 R-BTA-176700 https://reactome.org/PathwayBrowser/#/R-BTA-176700 Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure IEA Bos taurus A0A096LNF2 R-BTA-181450 https://reactome.org/PathwayBrowser/#/R-BTA-181450 Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure IEA Bos taurus A0A096LNF2 R-BTA-212222 https://reactome.org/PathwayBrowser/#/R-BTA-212222 PRC2 recruits DNA methyltransferases IEA Bos taurus A0A096LNF2 R-BTA-212252 https://reactome.org/PathwayBrowser/#/R-BTA-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Bos taurus A0A096LNF2 R-BTA-212263 https://reactome.org/PathwayBrowser/#/R-BTA-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Bos taurus A0A096LNF2 R-BTA-212269 https://reactome.org/PathwayBrowser/#/R-BTA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Bos taurus A0A096LNF2 R-BTA-2172678 https://reactome.org/PathwayBrowser/#/R-BTA-2172678 PHF8 demethylates histone H4K20me1 IEA Bos taurus A0A096LNF2 R-BTA-2245218 https://reactome.org/PathwayBrowser/#/R-BTA-2245218 CDK1 phosphorylates PHF8 IEA Bos taurus A0A096LNF2 R-BTA-2288097 https://reactome.org/PathwayBrowser/#/R-BTA-2288097 Condensin II complex binds H4K20me1-containing nucleosomes IEA Bos taurus A0A096LNF2 R-BTA-2294580 https://reactome.org/PathwayBrowser/#/R-BTA-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Bos taurus A0A096LNF2 R-BTA-2294590 https://reactome.org/PathwayBrowser/#/R-BTA-2294590 PLK1 binds phosphorylated condensin II complex IEA Bos taurus A0A096LNF2 R-BTA-2294600 https://reactome.org/PathwayBrowser/#/R-BTA-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Bos taurus A0A096LNF2 R-BTA-2301205 https://reactome.org/PathwayBrowser/#/R-BTA-2301205 SETD8 monomethylates histone H4 IEA Bos taurus A0A096LNF2 R-BTA-3222593 https://reactome.org/PathwayBrowser/#/R-BTA-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Bos taurus A0A096LNF2 R-BTA-3229089 https://reactome.org/PathwayBrowser/#/R-BTA-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Bos taurus A0A096LNF2 R-BTA-3229102 https://reactome.org/PathwayBrowser/#/R-BTA-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Bos taurus A0A096LNF2 R-BTA-3240295 https://reactome.org/PathwayBrowser/#/R-BTA-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Bos taurus A0A096LNF2 R-BTA-3364026 https://reactome.org/PathwayBrowser/#/R-BTA-3364026 SET1 complex trimethylates H3K4 at the MYC gene IEA Bos taurus A0A096LNF2 R-BTA-3662335 https://reactome.org/PathwayBrowser/#/R-BTA-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Bos taurus A0A096LNF2 R-BTA-3769447 https://reactome.org/PathwayBrowser/#/R-BTA-3769447 HDAC1:2-containing complex deacetylate histones IEA Bos taurus A0A096LNF2 R-BTA-3777129 https://reactome.org/PathwayBrowser/#/R-BTA-3777129 HDAC3 containing complexes deacetylate histone IEA Bos taurus A0A096LNF2 R-BTA-3782637 https://reactome.org/PathwayBrowser/#/R-BTA-3782637 HDAC8 deacetylates histones IEA Bos taurus A0A096LNF2 R-BTA-3782655 https://reactome.org/PathwayBrowser/#/R-BTA-3782655 HDAC10 deacetylates histone IEA Bos taurus A0A096LNF2 R-BTA-3785711 https://reactome.org/PathwayBrowser/#/R-BTA-3785711 Telomere shortening during replicative exhaustion IEA Bos taurus A0A096LNF2 R-BTA-3788745 https://reactome.org/PathwayBrowser/#/R-BTA-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Bos taurus A0A096LNF2 R-BTA-3788748 https://reactome.org/PathwayBrowser/#/R-BTA-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Bos taurus A0A096LNF2 R-BTA-427337 https://reactome.org/PathwayBrowser/#/R-BTA-427337 MBD2 binds methylcytosine in chromatin IEA Bos taurus A0A096LNF2 R-BTA-427514 https://reactome.org/PathwayBrowser/#/R-BTA-427514 eNoSC deacetylates histone H3 IEA Bos taurus A0A096LNF2 R-BTA-427527 https://reactome.org/PathwayBrowser/#/R-BTA-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Bos taurus A0A096LNF2 R-BTA-427528 https://reactome.org/PathwayBrowser/#/R-BTA-427528 Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) IEA Bos taurus A0A096LNF2 R-BTA-5205820 https://reactome.org/PathwayBrowser/#/R-BTA-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Bos taurus A0A096LNF2 R-BTA-5205867 https://reactome.org/PathwayBrowser/#/R-BTA-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Bos taurus A0A096LNF2 R-BTA-5216234 https://reactome.org/PathwayBrowser/#/R-BTA-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Bos taurus A0A096LNF2 R-BTA-5229203 https://reactome.org/PathwayBrowser/#/R-BTA-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Bos taurus A0A096LNF2 R-BTA-5250938 https://reactome.org/PathwayBrowser/#/R-BTA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Bos taurus A0A096LNF2 R-BTA-5578742 https://reactome.org/PathwayBrowser/#/R-BTA-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Bos taurus A0A096LNF2 R-BTA-5625774 https://reactome.org/PathwayBrowser/#/R-BTA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Bos taurus A0A096LNF2 R-BTA-5625784 https://reactome.org/PathwayBrowser/#/R-BTA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Bos taurus A0A096LNF2 R-BTA-5625796 https://reactome.org/PathwayBrowser/#/R-BTA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Bos taurus A0A096LNF2 R-BTA-5625797 https://reactome.org/PathwayBrowser/#/R-BTA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Bos taurus A0A096LNF2 R-BTA-5625848 https://reactome.org/PathwayBrowser/#/R-BTA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus A0A096LNF2 R-BTA-5625849 https://reactome.org/PathwayBrowser/#/R-BTA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Bos taurus A0A096LNF2 R-BTA-5625870 https://reactome.org/PathwayBrowser/#/R-BTA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus A0A096LNF2 R-BTA-5690080 https://reactome.org/PathwayBrowser/#/R-BTA-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Bos taurus A0A096LNF2 R-BTA-5690157 https://reactome.org/PathwayBrowser/#/R-BTA-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Bos taurus A0A096LNF2 R-BTA-5690790 https://reactome.org/PathwayBrowser/#/R-BTA-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Bos taurus A0A096LNF2 R-BTA-5691381 https://reactome.org/PathwayBrowser/#/R-BTA-5691381 MYSM1 deubiquitinates Histone H2A IEA Bos taurus A0A096LNF2 R-BTA-5691411 https://reactome.org/PathwayBrowser/#/R-BTA-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Bos taurus A0A096LNF2 R-BTA-606287 https://reactome.org/PathwayBrowser/#/R-BTA-606287 RSF complex binds the centromere IEA Bos taurus A0A096LNF2 R-BTA-606289 https://reactome.org/PathwayBrowser/#/R-BTA-606289 New CENPA-containing nucleosomes are deposited at the centromere IEA Bos taurus A0A096LNF2 R-BTA-73718 https://reactome.org/PathwayBrowser/#/R-BTA-73718 UBF-1 Binds rDNA Promoter IEA Bos taurus A0A096LNF2 R-BTA-74986 https://reactome.org/PathwayBrowser/#/R-BTA-74986 Elongation of pre-rRNA transcript IEA Bos taurus A0A096LNF2 R-BTA-8936481 https://reactome.org/PathwayBrowser/#/R-BTA-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Bos taurus A0A096LNF2 R-BTA-8936584 https://reactome.org/PathwayBrowser/#/R-BTA-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Bos taurus A0A096LNF2 R-BTA-8936608 https://reactome.org/PathwayBrowser/#/R-BTA-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Bos taurus A0A096LNF2 R-BTA-8936621 https://reactome.org/PathwayBrowser/#/R-BTA-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Bos taurus A0A096LNF2 R-BTA-8937016 https://reactome.org/PathwayBrowser/#/R-BTA-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Bos taurus A0A096LNF2 R-BTA-8937022 https://reactome.org/PathwayBrowser/#/R-BTA-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Bos taurus A0A096LNF2 R-BTA-8937050 https://reactome.org/PathwayBrowser/#/R-BTA-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Bos taurus A0A096LNF2 R-BTA-8937113 https://reactome.org/PathwayBrowser/#/R-BTA-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Bos taurus A0A096LNF2 R-BTA-9009065 https://reactome.org/PathwayBrowser/#/R-BTA-9009065 FOXA1 and GATA3 bind to CCND1 promoter IEA Bos taurus A0A096LNF2 R-BTA-9011949 https://reactome.org/PathwayBrowser/#/R-BTA-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Bos taurus A0A096LNF2 R-BTA-9011952 https://reactome.org/PathwayBrowser/#/R-BTA-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Bos taurus A0A096LNF2 R-BTA-9011983 https://reactome.org/PathwayBrowser/#/R-BTA-9011983 Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes IEA Bos taurus A0A096LNF2 R-BTA-9012000 https://reactome.org/PathwayBrowser/#/R-BTA-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Bos taurus A0A096LNF2 R-BTA-9629195 https://reactome.org/PathwayBrowser/#/R-BTA-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA IEA Bos taurus A0A096LNF2 R-BTA-9629216 https://reactome.org/PathwayBrowser/#/R-BTA-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Bos taurus A0A096LNF2 R-BTA-9670114 https://reactome.org/PathwayBrowser/#/R-BTA-9670114 Histone H3.3 deposition at telomere IEA Bos taurus A0A096LNF2 R-BTA-9749197 https://reactome.org/PathwayBrowser/#/R-BTA-9749197 ORC1 binds to H4K20me2 IEA Bos taurus A0A096LNF2 R-BTA-9842833 https://reactome.org/PathwayBrowser/#/R-BTA-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Bos taurus A0A096LNF2 R-BTA-9842839 https://reactome.org/PathwayBrowser/#/R-BTA-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Bos taurus A0A096LNF2 R-BTA-9843115 https://reactome.org/PathwayBrowser/#/R-BTA-9843115 Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci IEA Bos taurus A0A096LNF2 R-BTA-9843117 https://reactome.org/PathwayBrowser/#/R-BTA-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Bos taurus A0A096LNF2 R-BTA-9843118 https://reactome.org/PathwayBrowser/#/R-BTA-9843118 RXRA binds ligands IEA Bos taurus A0A096LNF2 R-BTA-9843120 https://reactome.org/PathwayBrowser/#/R-BTA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Bos taurus A0A096LNF2 R-BTA-9843978 https://reactome.org/PathwayBrowser/#/R-BTA-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Bos taurus A0A096LNF2 R-BTA-9844006 https://reactome.org/PathwayBrowser/#/R-BTA-9844006 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) IEA Bos taurus A0A096LNF2 R-BTA-9844015 https://reactome.org/PathwayBrowser/#/R-BTA-9844015 MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin IEA Bos taurus A0A096LNF2 R-BTA-9844057 https://reactome.org/PathwayBrowser/#/R-BTA-9844057 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome IEA Bos taurus A0A096LP49 R-HSA-9013110 https://reactome.org/PathwayBrowser/#/R-HSA-9013110 RHOC binds effectors at the plasma membrane TAS Homo sapiens A0A096LP55 R-HSA-9866132 https://reactome.org/PathwayBrowser/#/R-HSA-9866132 Intermediate II binds CYC1, UQCRC1, UQCRC2, UQCRH IEA Homo sapiens A0A096LP55 R-HSA-9866162 https://reactome.org/PathwayBrowser/#/R-HSA-9866162 Late core complex dimerizes IEA Homo sapiens A0A096LP55 R-HSA-9866164 https://reactome.org/PathwayBrowser/#/R-HSA-9866164 Late core complex dimer binds UQCR10, UQCR11, UQCRFS1. IEA Homo sapiens A0A096LP55 R-HSA-9906017 https://reactome.org/PathwayBrowser/#/R-HSA-9906017 Unknown peptidase cleaves UQCRFS1 subunit TAS Homo sapiens A0A096MIW0 R-RNO-5669012 https://reactome.org/PathwayBrowser/#/R-RNO-5669012 EDA binds EDAR IEA Rattus norvegicus A0A096MIW0 R-RNO-5669013 https://reactome.org/PathwayBrowser/#/R-RNO-5669013 EDA-3 binds EDA2R IEA Rattus norvegicus A0A096MIW0 R-RNO-5675656 https://reactome.org/PathwayBrowser/#/R-RNO-5675656 EDA:EDAR binds EDARADD IEA Rattus norvegicus A0A096MIZ0 R-RNO-5667008 https://reactome.org/PathwayBrowser/#/R-RNO-5667008 RHOA:GTP binds RHPN1 or RHPN2 IEA Rattus norvegicus A0A096MIZ0 R-RNO-9013009 https://reactome.org/PathwayBrowser/#/R-RNO-9013009 RHOA binds effectors at the plasma membrane IEA Rattus norvegicus A0A096MJ11 R-RNO-114284 https://reactome.org/PathwayBrowser/#/R-RNO-114284 Release of Cytochrome c from mitochondria IEA Rattus norvegicus A0A096MJ11 R-RNO-449058 https://reactome.org/PathwayBrowser/#/R-RNO-449058 Interleukin-1 family are secreted IEA Rattus norvegicus A0A096MJ11 R-RNO-6798745 https://reactome.org/PathwayBrowser/#/R-RNO-6798745 Exocytosis of tertiary granule lumen proteins IEA Rattus norvegicus A0A096MJ11 R-RNO-6798749 https://reactome.org/PathwayBrowser/#/R-RNO-6798749 Exocytosis of specific granule lumen proteins IEA Rattus norvegicus A0A096MJ11 R-RNO-6800434 https://reactome.org/PathwayBrowser/#/R-RNO-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Rattus norvegicus A0A096MJ11 R-RNO-6805981 https://reactome.org/PathwayBrowser/#/R-RNO-6805981 HMGB1 release from cells IEA Rattus norvegicus A0A096MJ11 R-RNO-9647619 https://reactome.org/PathwayBrowser/#/R-RNO-9647619 GSDMD forms ring‐shaped oligomers IEA Rattus norvegicus A0A096MJ11 R-RNO-9647631 https://reactome.org/PathwayBrowser/#/R-RNO-9647631 GSDMD (1-275) binds PIPs IEA Rattus norvegicus A0A096MJ11 R-RNO-9647643 https://reactome.org/PathwayBrowser/#/R-RNO-9647643 GSDMD (1-275) binds bacterial cardiolipin IEA Rattus norvegicus A0A096MJ11 R-RNO-9647645 https://reactome.org/PathwayBrowser/#/R-RNO-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Rattus norvegicus A0A096MJ11 R-RNO-9647680 https://reactome.org/PathwayBrowser/#/R-RNO-9647680 CASP1 cleaves GSDMD IEA Rattus norvegicus A0A096MJ11 R-RNO-9686088 https://reactome.org/PathwayBrowser/#/R-RNO-9686088 CASP3 cleaves GSDMD IEA Rattus norvegicus A0A096MJ11 R-RNO-9693324 https://reactome.org/PathwayBrowser/#/R-RNO-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Rattus norvegicus A0A096MJ11 R-RNO-9710106 https://reactome.org/PathwayBrowser/#/R-RNO-9710106 ELANE cleaves GSDMD IEA Rattus norvegicus A0A096MJ11 R-RNO-9710353 https://reactome.org/PathwayBrowser/#/R-RNO-9710353 GSDMD (1-275) binds cardiolipin IEA Rattus norvegicus A0A096MJ11 R-RNO-9716258 https://reactome.org/PathwayBrowser/#/R-RNO-9716258 Dimethyl fumarate modifies Cys191 in GSDMD IEA Rattus norvegicus A0A096MJ28 R-RNO-6814549 https://reactome.org/PathwayBrowser/#/R-RNO-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Rattus norvegicus A0A096MJ28 R-RNO-6814555 https://reactome.org/PathwayBrowser/#/R-RNO-6814555 Integrator complex processes the 3' end of snRNA IEA Rattus norvegicus A0A096MJ28 R-RNO-6814559 https://reactome.org/PathwayBrowser/#/R-RNO-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Rattus norvegicus A0A096MJ28 R-RNO-6814885 https://reactome.org/PathwayBrowser/#/R-RNO-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Rattus norvegicus A0A096MJ94 R-RNO-6791221 https://reactome.org/PathwayBrowser/#/R-RNO-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA IEA Rattus norvegicus A0A096MJ94 R-RNO-6791222 https://reactome.org/PathwayBrowser/#/R-RNO-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Rattus norvegicus A0A096MJ94 R-RNO-6791227 https://reactome.org/PathwayBrowser/#/R-RNO-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Rattus norvegicus A0A096MJ99 R-RNO-6811431 https://reactome.org/PathwayBrowser/#/R-RNO-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Rattus norvegicus A0A096MJ99 R-RNO-6814682 https://reactome.org/PathwayBrowser/#/R-RNO-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Rattus norvegicus A0A096MJ99 R-RNO-6814683 https://reactome.org/PathwayBrowser/#/R-RNO-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN IEA Rattus norvegicus A0A096MJ99 R-RNO-6814684 https://reactome.org/PathwayBrowser/#/R-RNO-6814684 cis-SNARE binds SNAPs and NSF hexamer at the TGN IEA Rattus norvegicus A0A096MJ99 R-RNO-8866277 https://reactome.org/PathwayBrowser/#/R-RNO-8866277 AP-2 directly binds some endocytic cargo IEA Rattus norvegicus A0A096MJ99 R-RNO-8867754 https://reactome.org/PathwayBrowser/#/R-RNO-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Rattus norvegicus A0A096MJ99 R-RNO-8867756 https://reactome.org/PathwayBrowser/#/R-RNO-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Rattus norvegicus A0A096MJ99 R-RNO-8868071 https://reactome.org/PathwayBrowser/#/R-RNO-8868071 Clathrin recruits PIK3C2A IEA Rattus norvegicus A0A096MJ99 R-RNO-8868072 https://reactome.org/PathwayBrowser/#/R-RNO-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Rattus norvegicus A0A096MJ99 R-RNO-8868236 https://reactome.org/PathwayBrowser/#/R-RNO-8868236 BAR domain proteins recruit dynamin IEA Rattus norvegicus A0A096MJ99 R-RNO-8868648 https://reactome.org/PathwayBrowser/#/R-RNO-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Rattus norvegicus A0A096MJ99 R-RNO-8868651 https://reactome.org/PathwayBrowser/#/R-RNO-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Rattus norvegicus A0A096MJ99 R-RNO-8868658 https://reactome.org/PathwayBrowser/#/R-RNO-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Rattus norvegicus A0A096MJ99 R-RNO-8868659 https://reactome.org/PathwayBrowser/#/R-RNO-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Rattus norvegicus A0A096MJ99 R-RNO-8868660 https://reactome.org/PathwayBrowser/#/R-RNO-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Rattus norvegicus A0A096MJ99 R-RNO-8868661 https://reactome.org/PathwayBrowser/#/R-RNO-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Rattus norvegicus A0A096MJ99 R-RNO-8871193 https://reactome.org/PathwayBrowser/#/R-RNO-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Rattus norvegicus A0A096MJ99 R-RNO-8871194 https://reactome.org/PathwayBrowser/#/R-RNO-8871194 RAB5 and GAPVD1 bind AP-2 IEA Rattus norvegicus A0A096MJE3 R-RNO-927789 https://reactome.org/PathwayBrowser/#/R-RNO-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Rattus norvegicus A0A096MJE3 R-RNO-927813 https://reactome.org/PathwayBrowser/#/R-RNO-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Rattus norvegicus A0A096MJE3 R-RNO-927832 https://reactome.org/PathwayBrowser/#/R-RNO-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Rattus norvegicus A0A096MJE3 R-RNO-927836 https://reactome.org/PathwayBrowser/#/R-RNO-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Rattus norvegicus A0A096MJE3 R-RNO-927889 https://reactome.org/PathwayBrowser/#/R-RNO-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Rattus norvegicus A0A096MJE4 R-RNO-388808 https://reactome.org/PathwayBrowser/#/R-RNO-388808 CD28 homodimer binds B7-2 monomer IEA Rattus norvegicus A0A096MJE4 R-RNO-388809 https://reactome.org/PathwayBrowser/#/R-RNO-388809 CTLA-4 binds B7-1/B7-2 IEA Rattus norvegicus A0A096MJE4 R-RNO-388811 https://reactome.org/PathwayBrowser/#/R-RNO-388811 CD28 homodimer binds B7-1 homodimer IEA Rattus norvegicus A0A096MJE4 R-RNO-388829 https://reactome.org/PathwayBrowser/#/R-RNO-388829 SHP2 phosphatase binds CTLA-4 IEA Rattus norvegicus A0A096MJE4 R-RNO-388833 https://reactome.org/PathwayBrowser/#/R-RNO-388833 Phosphorylation of CTLA-4 IEA Rattus norvegicus A0A096MJE4 R-RNO-389532 https://reactome.org/PathwayBrowser/#/R-RNO-389532 PP2A binds CTLA4 dimer IEA Rattus norvegicus A0A096MJF6 R-RNO-176298 https://reactome.org/PathwayBrowser/#/R-RNO-176298 Activation of claspin IEA Rattus norvegicus A0A096MJF6 R-RNO-176318 https://reactome.org/PathwayBrowser/#/R-RNO-176318 Loading of claspin onto DNA during replication origin firing IEA Rattus norvegicus A0A096MJF6 R-RNO-68914 https://reactome.org/PathwayBrowser/#/R-RNO-68914 DNA polymerase alpha:primase binds at the origin IEA Rattus norvegicus A0A096MJF6 R-RNO-68916 https://reactome.org/PathwayBrowser/#/R-RNO-68916 DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin IEA Rattus norvegicus A0A096MJF6 R-RNO-68918 https://reactome.org/PathwayBrowser/#/R-RNO-68918 CDK and DDK associate with the Mcm10:pre-replicative complex IEA Rattus norvegicus A0A096MJF6 R-RNO-68954 https://reactome.org/PathwayBrowser/#/R-RNO-68954 Mcm2-7 is phosphorylated by DDK IEA Rattus norvegicus A0A096MJF6 R-RNO-68960 https://reactome.org/PathwayBrowser/#/R-RNO-68960 DNA polymerase epsilon binds at the origin IEA Rattus norvegicus A0A096MJM8 R-RNO-6791218 https://reactome.org/PathwayBrowser/#/R-RNO-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Rattus norvegicus A0A096MJM8 R-RNO-6791219 https://reactome.org/PathwayBrowser/#/R-RNO-6791219 32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA IEA Rattus norvegicus A0A096MJN4 R-RNO-6805811 https://reactome.org/PathwayBrowser/#/R-RNO-6805811 Release of SEPT4 from mitochondria IEA Rattus norvegicus A0A096MJN4 R-RNO-9627369 https://reactome.org/PathwayBrowser/#/R-RNO-9627369 SEPT4 binds XIAP IEA Rattus norvegicus A0A096MJP5 R-RNO-5669013 https://reactome.org/PathwayBrowser/#/R-RNO-5669013 EDA-3 binds EDA2R IEA Rattus norvegicus A0A096MJS6 R-RNO-8940388 https://reactome.org/PathwayBrowser/#/R-RNO-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Rattus norvegicus A0A096MJS9 R-RNO-2468039 https://reactome.org/PathwayBrowser/#/R-RNO-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Rattus norvegicus A0A096MJS9 R-RNO-2473152 https://reactome.org/PathwayBrowser/#/R-RNO-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Rattus norvegicus A0A096MJV7 R-RNO-400143 https://reactome.org/PathwayBrowser/#/R-RNO-400143 Fatty acid ligands activate PPARA IEA Rattus norvegicus A0A096MJW8 R-RNO-1855221 https://reactome.org/PathwayBrowser/#/R-RNO-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Rattus norvegicus A0A096MJY2 R-RNO-8863494 https://reactome.org/PathwayBrowser/#/R-RNO-8863494 ASICs bind STOML3, (STOM) IEA Rattus norvegicus A0A096MJY4 R-RNO-448955 https://reactome.org/PathwayBrowser/#/R-RNO-448955 Phosphorylation of MEF2 proteins by p38 IEA Rattus norvegicus A0A096MJY4 R-RNO-448963 https://reactome.org/PathwayBrowser/#/R-RNO-448963 Interaction of MyoD:E protein with MEF2 IEA Rattus norvegicus A0A096MK02 R-RNO-8940554 https://reactome.org/PathwayBrowser/#/R-RNO-8940554 MMP2 cleaves OPTC IEA Rattus norvegicus A0A096MK02 R-RNO-8940561 https://reactome.org/PathwayBrowser/#/R-RNO-8940561 MMP7 cleaves OPTC IEA Rattus norvegicus A0A096MK02 R-RNO-8942302 https://reactome.org/PathwayBrowser/#/R-RNO-8942302 MMP13 cleaves OPTC IEA Rattus norvegicus A0A096MK16 R-RNO-8981637 https://reactome.org/PathwayBrowser/#/R-RNO-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Rattus norvegicus A0A096MK16 R-RNO-9013144 https://reactome.org/PathwayBrowser/#/R-RNO-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Rattus norvegicus A0A096MK16 R-RNO-9013161 https://reactome.org/PathwayBrowser/#/R-RNO-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Rattus norvegicus A0A096MK32 R-RNO-110218 https://reactome.org/PathwayBrowser/#/R-RNO-110218 Cleavage of uracil by TDG glycosylase IEA Rattus norvegicus A0A096MK32 R-RNO-110219 https://reactome.org/PathwayBrowser/#/R-RNO-110219 Cleavage of thymine by TDG glycosylase IEA Rattus norvegicus A0A096MK32 R-RNO-110234 https://reactome.org/PathwayBrowser/#/R-RNO-110234 Cleavage of ethenocytosine by TDG glycosylase IEA Rattus norvegicus A0A096MK32 R-RNO-110350 https://reactome.org/PathwayBrowser/#/R-RNO-110350 Displacement of TDG glycosylase by APEX1 at the AP site IEA Rattus norvegicus A0A096MK32 R-RNO-4551648 https://reactome.org/PathwayBrowser/#/R-RNO-4551648 SUMOylation of TDG with SUMO1 IEA Rattus norvegicus A0A096MK32 R-RNO-4551738 https://reactome.org/PathwayBrowser/#/R-RNO-4551738 SUMOylation of TDG with SUMO2,3 IEA Rattus norvegicus A0A096MK32 R-RNO-5220959 https://reactome.org/PathwayBrowser/#/R-RNO-5220959 TDG excises 5-formylcytosine IEA Rattus norvegicus A0A096MK32 R-RNO-5221061 https://reactome.org/PathwayBrowser/#/R-RNO-5221061 TDG excises 5-carboxylcytosine IEA Rattus norvegicus A0A096MK86 R-RNO-381518 https://reactome.org/PathwayBrowser/#/R-RNO-381518 PAAP-A proteolyzes IGF:IGFBP4 IEA Rattus norvegicus A0A096MK86 R-RNO-381537 https://reactome.org/PathwayBrowser/#/R-RNO-381537 PAPP-A2 proteolyzes IGF:IGFBP5:ALS IEA Rattus norvegicus A0A096MKA6 R-RNO-5634802 https://reactome.org/PathwayBrowser/#/R-RNO-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) IEA Rattus norvegicus A0A096MKD1 R-RNO-8931974 https://reactome.org/PathwayBrowser/#/R-RNO-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Rattus norvegicus A0A096MKE0 R-RNO-2855020 https://reactome.org/PathwayBrowser/#/R-RNO-2855020 RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol IEA Rattus norvegicus A0A096MKF8 R-RNO-9843120 https://reactome.org/PathwayBrowser/#/R-RNO-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Rattus norvegicus A0A096MKH4 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A096MKH4 R-RNO-983152 https://reactome.org/PathwayBrowser/#/R-RNO-983152 Transfer of ubiquitin from E1 to E2 IEA Rattus norvegicus A0A096MKH4 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A096MKH4 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A096MKI6 R-RNO-5689317 https://reactome.org/PathwayBrowser/#/R-RNO-5689317 Formation of the pre-incision complex in GG-NER IEA Rattus norvegicus A0A096MKI6 R-RNO-5690213 https://reactome.org/PathwayBrowser/#/R-RNO-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Rattus norvegicus A0A096MKI6 R-RNO-5690988 https://reactome.org/PathwayBrowser/#/R-RNO-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Rattus norvegicus A0A096MKI6 R-RNO-5690990 https://reactome.org/PathwayBrowser/#/R-RNO-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Rattus norvegicus A0A096MKI6 R-RNO-5690991 https://reactome.org/PathwayBrowser/#/R-RNO-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER IEA Rattus norvegicus A0A096MKI6 R-RNO-6782138 https://reactome.org/PathwayBrowser/#/R-RNO-6782138 ERCC5 and RPA bind TC-NER site IEA Rattus norvegicus A0A096MKI6 R-RNO-6782141 https://reactome.org/PathwayBrowser/#/R-RNO-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Rattus norvegicus A0A096MKI6 R-RNO-6782204 https://reactome.org/PathwayBrowser/#/R-RNO-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Rattus norvegicus A0A096MKI6 R-RNO-6782211 https://reactome.org/PathwayBrowser/#/R-RNO-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Rattus norvegicus A0A096MKI6 R-RNO-6782224 https://reactome.org/PathwayBrowser/#/R-RNO-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Rattus norvegicus A0A096UWG1 R-RNO-264418 https://reactome.org/PathwayBrowser/#/R-RNO-264418 Translocation of COP1 from the nucleus to the cytoplasm IEA Rattus norvegicus A0A096UWG1 R-RNO-264435 https://reactome.org/PathwayBrowser/#/R-RNO-264435 Dissociation of the COP1-p53 complex IEA Rattus norvegicus A0A096UWG1 R-RNO-264444 https://reactome.org/PathwayBrowser/#/R-RNO-264444 Autoubiquitination of phospho-COP1(Ser-387 ) IEA Rattus norvegicus A0A096UWG1 R-RNO-264458 https://reactome.org/PathwayBrowser/#/R-RNO-264458 Proteasome mediated degradation of COP1 IEA Rattus norvegicus A0A096UWG1 R-RNO-349444 https://reactome.org/PathwayBrowser/#/R-RNO-349444 Phosphorylation of COP1 at Ser-387 by ATM IEA Rattus norvegicus A0A096UWG1 R-RNO-8952638 https://reactome.org/PathwayBrowser/#/R-RNO-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A096UWG1 R-RNO-8952639 https://reactome.org/PathwayBrowser/#/R-RNO-8952639 NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A096UWG1 R-RNO-8955245 https://reactome.org/PathwayBrowser/#/R-RNO-8955245 CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus IEA Rattus norvegicus A0A096UWG1 R-RNO-8955285 https://reactome.org/PathwayBrowser/#/R-RNO-8955285 COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A096UWG1 R-RNO-8956045 https://reactome.org/PathwayBrowser/#/R-RNO-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A096UWG9 R-RNO-426240 https://reactome.org/PathwayBrowser/#/R-RNO-426240 DAG kinase produces phosphatidic acid from DAG IEA Rattus norvegicus A0A097HUX0 R-DRE-209868 https://reactome.org/PathwayBrowser/#/R-DRE-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Danio rerio A0A0A0MP93 R-BTA-3662335 https://reactome.org/PathwayBrowser/#/R-BTA-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Bos taurus A0A0A0MP93 R-BTA-3769447 https://reactome.org/PathwayBrowser/#/R-BTA-3769447 HDAC1:2-containing complex deacetylate histones IEA Bos taurus A0A0A0MP93 R-BTA-3777129 https://reactome.org/PathwayBrowser/#/R-BTA-3777129 HDAC3 containing complexes deacetylate histone IEA Bos taurus A0A0A0MP93 R-BTA-3782637 https://reactome.org/PathwayBrowser/#/R-BTA-3782637 HDAC8 deacetylates histones IEA Bos taurus A0A0A0MP93 R-BTA-3782655 https://reactome.org/PathwayBrowser/#/R-BTA-3782655 HDAC10 deacetylates histone IEA Bos taurus A0A0A0MP93 R-BTA-5205820 https://reactome.org/PathwayBrowser/#/R-BTA-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Bos taurus A0A0A0MP93 R-BTA-5205867 https://reactome.org/PathwayBrowser/#/R-BTA-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Bos taurus A0A0A0MP93 R-BTA-5216234 https://reactome.org/PathwayBrowser/#/R-BTA-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Bos taurus A0A0A0MP93 R-BTA-5229203 https://reactome.org/PathwayBrowser/#/R-BTA-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Bos taurus A0A0A0MP93 R-BTA-5690080 https://reactome.org/PathwayBrowser/#/R-BTA-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Bos taurus A0A0A0MP93 R-BTA-5690157 https://reactome.org/PathwayBrowser/#/R-BTA-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Bos taurus A0A0A0MP93 R-BTA-5690790 https://reactome.org/PathwayBrowser/#/R-BTA-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Bos taurus A0A0A0MP93 R-BTA-5691381 https://reactome.org/PathwayBrowser/#/R-BTA-5691381 MYSM1 deubiquitinates Histone H2A IEA Bos taurus A0A0A0MP93 R-BTA-5691411 https://reactome.org/PathwayBrowser/#/R-BTA-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Bos taurus A0A0A0MQ32 R-GGA-2002466 https://reactome.org/PathwayBrowser/#/R-GGA-2002466 Formation of allysine by LOX IEA Gallus gallus A0A0A0MQ32 R-GGA-2129375 https://reactome.org/PathwayBrowser/#/R-GGA-2129375 Elastin cross-linking by lysyl oxidase IEA Gallus gallus A0A0A0MQ32 R-GGA-2395340 https://reactome.org/PathwayBrowser/#/R-GGA-2395340 Formation of hydroxyallysine by LOX IEA Gallus gallus A0A0A0MQ42 R-GGA-5674366 https://reactome.org/PathwayBrowser/#/R-GGA-5674366 IL17RD binds p-2S MAP2Ks and MAPKs IEA Gallus gallus A0A0A0MQ42 R-GGA-5674373 https://reactome.org/PathwayBrowser/#/R-GGA-5674373 MAP2Ks phosphorylate MAPK at the Golgi membrane IEA Gallus gallus A0A0A0MQ45 R-GGA-2168079 https://reactome.org/PathwayBrowser/#/R-GGA-2168079 MASTL (GWL) phosphorylates ARPP19 IEA Gallus gallus A0A0A0MQ45 R-GGA-2430535 https://reactome.org/PathwayBrowser/#/R-GGA-2430535 MASTL phosphorylates ENSA IEA Gallus gallus A0A0A0MQ60 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A0A0MQ60 R-GGA-419334 https://reactome.org/PathwayBrowser/#/R-GGA-419334 Melatonin receptors can bind melatonin IEA Gallus gallus A0A0A0MQ60 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A0A0MQ60 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A0A0MQA4 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A0A0MY58 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A0A0MY58 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A0A0MY58 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A0A0MY58 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A0A0MY58 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A0A0MY58 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A0A0MY58 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A0A0MY58 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A0A0MY58 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A0A0MY58 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A0A0MY58 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A0A0MY58 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A0A0MY58 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A0A0MY58 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A0A0MY58 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A0A0MY58 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A0A0MY58 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A0A0MY58 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A0A0MY58 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A0A0MY58 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A0A0MY58 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A0A0MY58 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A0A0MY58 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A0A0MY58 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A0A0MY58 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A0A0MY58 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A0A0MY58 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A0A0MY58 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A0A0MY58 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A0A0MY58 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A0A0MY58 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A0A0MY58 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A0A0MY58 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A0A0MY58 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A0A0MY58 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A0A0MY58 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A0A0MY58 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A0A0MY58 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A0A0MY58 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A0A0MY58 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A0A0MY58 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A0A0MY58 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A0A0MY58 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A0A0MY58 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A0A0MY58 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A0A0MY58 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A0A0MY58 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A0A0MY60 R-SSC-1254285 https://reactome.org/PathwayBrowser/#/R-SSC-1254285 ERBB4s80:STAT5A complex translocates to the nucleus IEA Sus scrofa A0A0A0MY60 R-SSC-1254291 https://reactome.org/PathwayBrowser/#/R-SSC-1254291 ERBB4s80 binds STAT5A IEA Sus scrofa A0A0A0MY60 R-SSC-1295540 https://reactome.org/PathwayBrowser/#/R-SSC-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 IEA Sus scrofa A0A0A0MY60 R-SSC-1433456 https://reactome.org/PathwayBrowser/#/R-SSC-1433456 Recruitment of STATs IEA Sus scrofa A0A0A0MY60 R-SSC-1470009 https://reactome.org/PathwayBrowser/#/R-SSC-1470009 Phosphorylation of STATs IEA Sus scrofa A0A0A0MY60 R-SSC-1470010 https://reactome.org/PathwayBrowser/#/R-SSC-1470010 Dimerization of STATs IEA Sus scrofa A0A0A0MY60 R-SSC-1470012 https://reactome.org/PathwayBrowser/#/R-SSC-1470012 Disassociation and translocation of STATs to the nucleus IEA Sus scrofa A0A0A0MY60 R-SSC-380782 https://reactome.org/PathwayBrowser/#/R-SSC-380782 STAT binds to the active receptor IEA Sus scrofa A0A0A0MY60 R-SSC-452097 https://reactome.org/PathwayBrowser/#/R-SSC-452097 Recruited STAT5 is phosphorylated IEA Sus scrofa A0A0A0MY60 R-SSC-452108 https://reactome.org/PathwayBrowser/#/R-SSC-452108 Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment IEA Sus scrofa A0A0A0MY60 R-SSC-6785165 https://reactome.org/PathwayBrowser/#/R-SSC-6785165 p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B IEA Sus scrofa A0A0A0MY60 R-SSC-879909 https://reactome.org/PathwayBrowser/#/R-SSC-879909 Activation of STAT5a/b by JAK2 IEA Sus scrofa A0A0A0MY60 R-SSC-879930 https://reactome.org/PathwayBrowser/#/R-SSC-879930 STAT5 is recruited by JAK2 IEA Sus scrofa A0A0A0MY60 R-SSC-8983371 https://reactome.org/PathwayBrowser/#/R-SSC-8983371 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 IEA Sus scrofa A0A0A0MY60 R-SSC-8983373 https://reactome.org/PathwayBrowser/#/R-SSC-8983373 p-Y-STAT3 binds p-STAT5 IEA Sus scrofa A0A0A0MY60 R-SSC-8983374 https://reactome.org/PathwayBrowser/#/R-SSC-8983374 p-Y-STAT3 and p-STAT5 dissociates from IL15:IL15RA:IL2RB:p-JAK1:IL2RG:p-JAK3:p-Y-STAT3:p-STAT5 IEA Sus scrofa A0A0A0MY60 R-SSC-8983378 https://reactome.org/PathwayBrowser/#/R-SSC-8983378 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 IEA Sus scrofa A0A0A0MY60 R-SSC-8983379 https://reactome.org/PathwayBrowser/#/R-SSC-8983379 p-Y-STAT3:p-STAT5 translocates to the nucleus IEA Sus scrofa A0A0A0MY60 R-SSC-8985900 https://reactome.org/PathwayBrowser/#/R-SSC-8985900 p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 IEA Sus scrofa A0A0A0MY60 R-SSC-8985929 https://reactome.org/PathwayBrowser/#/R-SSC-8985929 IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B IEA Sus scrofa A0A0A0MY60 R-SSC-8985950 https://reactome.org/PathwayBrowser/#/R-SSC-8985950 p-Y694-STAT5A, p-STAT5B dimerizes IEA Sus scrofa A0A0A0MY60 R-SSC-8985988 https://reactome.org/PathwayBrowser/#/R-SSC-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Sus scrofa A0A0A0MY60 R-SSC-8986985 https://reactome.org/PathwayBrowser/#/R-SSC-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Sus scrofa A0A0A0MY60 R-SSC-8987033 https://reactome.org/PathwayBrowser/#/R-SSC-8987033 p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 IEA Sus scrofa A0A0A0MY60 R-SSC-8987266 https://reactome.org/PathwayBrowser/#/R-SSC-8987266 IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 IEA Sus scrofa A0A0A0MY60 R-SSC-9006870 https://reactome.org/PathwayBrowser/#/R-SSC-9006870 IL21 receptor STAT phosphorylation IEA Sus scrofa A0A0A0MY60 R-SSC-9006873 https://reactome.org/PathwayBrowser/#/R-SSC-9006873 IL21 receptor STAT binding IEA Sus scrofa A0A0A0MY60 R-SSC-9025969 https://reactome.org/PathwayBrowser/#/R-SSC-9025969 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 binds STAT5 IEA Sus scrofa A0A0A0MY60 R-SSC-919404 https://reactome.org/PathwayBrowser/#/R-SSC-919404 Phosphorylated STAT5 is released IEA Sus scrofa A0A0A0MY60 R-SSC-921155 https://reactome.org/PathwayBrowser/#/R-SSC-921155 p-STAT5 dissociates from the receptor complex IEA Sus scrofa A0A0A0RBT6 R-CFA-421831 https://reactome.org/PathwayBrowser/#/R-CFA-421831 trans-Golgi Network Coat Assembly IEA Canis familiaris A0A0A0RBT6 R-CFA-421833 https://reactome.org/PathwayBrowser/#/R-CFA-421833 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture IEA Canis familiaris A0A0A0RBT6 R-CFA-421835 https://reactome.org/PathwayBrowser/#/R-CFA-421835 trans-Golgi Network Vesicle Scission IEA Canis familiaris A0A0A0RBT6 R-CFA-421836 https://reactome.org/PathwayBrowser/#/R-CFA-421836 trans-Golgi Network Derived Vesicle Uncoating IEA Canis familiaris A0A0A0RBT6 R-CFA-5691154 https://reactome.org/PathwayBrowser/#/R-CFA-5691154 HFE binds TFRC dimer IEA Canis familiaris A0A0A0RBT6 R-CFA-9013009 https://reactome.org/PathwayBrowser/#/R-CFA-9013009 RHOA binds effectors at the plasma membrane IEA Canis familiaris A0A0A0RBT6 R-CFA-9013024 https://reactome.org/PathwayBrowser/#/R-CFA-9013024 RHOB binds effectors at the plasma membrane IEA Canis familiaris A0A0A0RBT6 R-CFA-9013110 https://reactome.org/PathwayBrowser/#/R-CFA-9013110 RHOC binds effectors at the plasma membrane IEA Canis familiaris A0A0A0RBT6 R-CFA-9013145 https://reactome.org/PathwayBrowser/#/R-CFA-9013145 RAC1 binds effectors at the plasma membrane IEA Canis familiaris A0A0A0RBT6 R-CFA-9013157 https://reactome.org/PathwayBrowser/#/R-CFA-9013157 CDC42 binds effectors at the plasma membrane IEA Canis familiaris A0A0A0RBT6 R-CFA-9014294 https://reactome.org/PathwayBrowser/#/R-CFA-9014294 RAC2 binds effectors at the plasma membrane IEA Canis familiaris A0A0A0RBT6 R-CFA-9014449 https://reactome.org/PathwayBrowser/#/R-CFA-9014449 RHOG binds effectors at the plasma membrane IEA Canis familiaris A0A0A0RBT6 R-CFA-9018746 https://reactome.org/PathwayBrowser/#/R-CFA-9018746 RHOQ binds effectors at the plasma membrane IEA Canis familiaris A0A0A0RBT6 R-CFA-9018758 https://reactome.org/PathwayBrowser/#/R-CFA-9018758 RHOH binds effectors at the plasma membrane IEA Canis familiaris A0A0A0RBT6 R-CFA-9018808 https://reactome.org/PathwayBrowser/#/R-CFA-9018808 RAC3 binds effectors at the plasma membrane IEA Canis familiaris A0A0A0RBT6 R-CFA-9696266 https://reactome.org/PathwayBrowser/#/R-CFA-9696266 RND2 binds effectors IEA Canis familiaris A0A0A0RBT6 R-CFA-9696271 https://reactome.org/PathwayBrowser/#/R-CFA-9696271 RND1 binds effectors IEA Canis familiaris A0A0A6YW14 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A0A6YW14 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A0A6YW14 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A0A6YW14 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A0A6YW14 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A0A6YW14 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A0A6YW14 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A0A6YW14 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A0A6YW14 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A0A6YW14 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A0A6YW33 R-MMU-156826 https://reactome.org/PathwayBrowser/#/R-MMU-156826 Dissociation of L13a from the 60s ribosomal subunit IEA Mus musculus A0A0A6YW33 R-MMU-1799332 https://reactome.org/PathwayBrowser/#/R-MMU-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Mus musculus A0A0A6YW33 R-MMU-6791218 https://reactome.org/PathwayBrowser/#/R-MMU-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Mus musculus A0A0A6YW33 R-MMU-72671 https://reactome.org/PathwayBrowser/#/R-MMU-72671 eIF5B:GTP is hydrolyzed and released IEA Mus musculus A0A0A6YW33 R-MMU-72672 https://reactome.org/PathwayBrowser/#/R-MMU-72672 The 60S subunit joins the translation initiation complex IEA Mus musculus A0A0A6YW33 R-MMU-72673 https://reactome.org/PathwayBrowser/#/R-MMU-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Mus musculus A0A0A6YW33 R-MMU-927789 https://reactome.org/PathwayBrowser/#/R-MMU-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Mus musculus A0A0A6YW33 R-MMU-927813 https://reactome.org/PathwayBrowser/#/R-MMU-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Mus musculus A0A0A6YW33 R-MMU-927832 https://reactome.org/PathwayBrowser/#/R-MMU-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Mus musculus A0A0A6YW33 R-MMU-927836 https://reactome.org/PathwayBrowser/#/R-MMU-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Mus musculus A0A0A6YW33 R-MMU-927889 https://reactome.org/PathwayBrowser/#/R-MMU-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Mus musculus A0A0A6YW58 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A0A6YW58 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A0A6YW58 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A0A6YW58 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A0A6YW58 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A0A6YW58 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A0A6YW58 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A0A6YW58 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A0A6YW58 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A0A6YW58 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A0A6YW58 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A0A6YW58 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A0A6YW58 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A0A6YW58 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A0A6YW58 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A0A6YW58 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A0A6YW58 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A0A6YW58 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A0A6YW58 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A0A6YW58 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A0A6YW58 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A0A6YW58 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A0A6YW58 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A0A6YW58 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A0A6YW58 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A0A6YW58 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A0A6YW58 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A0A6YW58 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A0A6YW58 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A0A6YW58 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A0A6YW58 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A0A6YW58 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A0A6YW58 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A0A6YW58 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A0A6YW58 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A0A6YW58 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A0A6YW58 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A0A6YW58 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A0A6YW58 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A0A6YW58 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A0A6YW58 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A0A6YW58 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A0A6YW58 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A0A6YW58 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A0A6YW58 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A0A6YW58 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A0A6YW58 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A0A6YW58 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A0A6YWG4 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A0A6YWG4 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A0A6YWG4 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A0A6YWG4 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A0A6YWG4 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A0A6YWG4 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A0A6YWG4 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A0A6YWG4 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A0A6YWG4 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A0A6YWG4 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A0A6YWG4 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A0A6YWG4 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A0A6YWG4 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A0A6YWG4 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A0A6YWG4 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A0A6YWG4 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A0A6YWG4 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A0A6YWG4 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A0A6YWG4 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A0A6YWG4 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A0A6YWG4 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A0A6YWG4 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A0A6YWG4 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A0A6YWG4 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A0A6YWG4 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A0A6YWG4 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A0A6YWG4 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A0A6YWG4 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A0A6YWG4 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A0A6YWG4 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A0A6YWG4 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A0A6YWG4 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A0A6YWG4 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A0A6YWG4 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A0A6YWG4 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A0A6YWG4 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A0A6YWG4 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A0A6YWG4 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A0A6YWG4 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A0A6YWG4 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A0A6YWG4 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A0A6YWG4 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A0A6YWG4 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A0A6YWG4 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A0A6YWG4 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A0A6YWG4 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A0A6YWG4 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A0A6YWG4 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A0A6YWU3 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A0A6YWU3 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A0A6YWU3 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A0A6YWU3 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A0A6YWU3 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A0A6YWU3 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A0A6YWU3 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A0A6YWU3 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A0A6YWU3 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A0A6YWU3 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A0A6YWU3 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A0A6YWU3 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A0A6YWU3 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A0A6YWU3 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A0A6YWU3 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A0A6YWU3 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A0A6YWU3 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A0A6YWU3 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A0A6YWU3 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A0A6YWU3 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A0A6YWU3 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A0A6YWU3 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A0A6YWU3 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A0A6YWU3 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A0A6YWU3 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A0A6YWU3 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A0A6YWU3 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A0A6YWU3 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A0A6YWU3 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A0A6YWU3 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A0A6YWU3 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A0A6YWU3 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A0A6YWU3 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A0A6YWU3 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A0A6YWU3 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A0A6YWU3 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A0A6YWU3 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A0A6YWU3 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A0A6YWU3 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A0A6YWU3 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A0A6YWU3 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A0A6YWU3 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A0A6YWU3 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A0A6YWU3 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A0A6YWU3 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A0A6YWU3 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A0A6YWU3 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A0A6YWU3 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A0A6YXF1 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A0A6YXF1 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A0A6YXF1 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A0A6YXF1 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A0A6YXF1 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A0A6YXF1 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A0A6YXF1 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A0A6YXF1 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A0A6YXF1 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A0A6YXF1 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A0A6YXF1 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A0A6YXF1 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A0A6YXF1 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A0A6YXF1 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A0A6YXF1 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A0A6YXF1 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A0A6YXF1 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A0A6YXF1 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A0A6YXF1 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A0A6YXF1 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A0A6YXF1 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A0A6YXF1 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A0A6YXF1 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A0A6YXF1 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A0A6YXF1 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A0A6YXF1 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A0A6YXF1 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A0A6YXF1 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A0A6YXF1 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A0A6YXF1 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A0A6YXF1 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A0A6YXF1 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A0A6YXF1 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A0A6YXF1 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A0A6YXF1 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A0A6YXF1 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A0A6YXF1 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A0A6YXF1 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A0A6YXF1 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A0A6YXF1 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A0A6YXF1 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A0A6YXF1 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A0A6YXF1 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A0A6YXF1 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A0A6YXF1 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A0A6YXF1 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A0A6YXF1 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A0A6YXF1 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A0A6YXN8 R-MMU-202703 https://reactome.org/PathwayBrowser/#/R-MMU-202703 CD47 binds SIRP IEA Mus musculus A0A0A6YXN8 R-MMU-391168 https://reactome.org/PathwayBrowser/#/R-MMU-391168 SIRP gamma binds CD47 IEA Mus musculus A0A0A6YXQ0 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A0A6YXQ0 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A0A6YXQ0 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A0A6YXQ0 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A0A6YXQ0 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A0A6YXQ0 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A0A6YXQ0 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A0A6YXQ0 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A0A6YXQ0 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A0A6YXQ0 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A0A6YXQ0 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A0A6YXQ0 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A0A6YXQ0 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A0A6YXQ0 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A0A6YXQ0 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A0A6YXQ0 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A0A6YXQ0 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A0A6YXQ0 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A0A6YXQ0 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A0A6YXQ0 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A0A6YXQ0 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A0A6YXQ0 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A0A6YXQ0 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A0A6YXQ0 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A0A6YXQ0 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A0A6YXQ0 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A0A6YXQ0 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A0A6YXQ0 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A0A6YXQ0 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A0A6YXQ0 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A0A6YXQ0 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A0A6YXQ0 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A0A6YXQ0 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A0A6YXQ0 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A0A6YXQ0 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A0A6YXQ0 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A0A6YXQ0 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A0A6YXQ0 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A0A6YXQ0 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A0A6YXQ0 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A0A6YXQ0 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A0A6YXQ0 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A0A6YXQ0 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A0A6YXQ0 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A0A6YXQ0 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A0A6YXQ0 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A0A6YXQ0 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A0A6YXQ0 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A0A6YXW6 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A0A6YXW6 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A0A6YY60 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A0A6YY60 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A0A6YY60 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A0A6YY60 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A0A6YY60 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A0A6YY60 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A0A6YY60 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A0A6YY60 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A0A6YY60 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A0A6YY60 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A0A6YY60 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A0A6YY60 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A0A6YY60 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A0A6YY60 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A0A6YY60 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A0A6YY60 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A0A6YY60 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A0A6YY60 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A0A6YY60 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A0A6YY60 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A0A6YY60 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A0A6YY60 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A0A6YY60 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A0A6YY60 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A0A6YY60 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A0A6YY60 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A0A6YY60 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A0A6YY60 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A0A6YY60 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A0A6YY60 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A0A6YY60 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A0A6YY60 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A0A6YY60 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A0A6YY60 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A0A6YY60 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A0A6YY60 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A0A6YY60 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A0A6YY60 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A0A6YY60 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A0A6YY60 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A0A6YY60 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A0A6YY60 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A0A6YY60 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A0A6YY60 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A0A6YY60 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A0A6YY60 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A0A6YY60 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A0A6YY60 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A0A6YY83 R-MMU-481044 https://reactome.org/PathwayBrowser/#/R-MMU-481044 Surface deployment of platelet alpha granule membrane components IEA Mus musculus A0A0A6YY83 R-MMU-9013009 https://reactome.org/PathwayBrowser/#/R-MMU-9013009 RHOA binds effectors at the plasma membrane IEA Mus musculus A0A0A6YY83 R-MMU-9013024 https://reactome.org/PathwayBrowser/#/R-MMU-9013024 RHOB binds effectors at the plasma membrane IEA Mus musculus A0A0A6YYE3 R-MMU-198955 https://reactome.org/PathwayBrowser/#/R-MMU-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Mus musculus A0A0A6YYE3 R-MMU-202165 https://reactome.org/PathwayBrowser/#/R-MMU-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Mus musculus A0A0A6YYE3 R-MMU-202168 https://reactome.org/PathwayBrowser/#/R-MMU-202168 Phosphorylation of ZAP-70 by Lck IEA Mus musculus A0A0A6YYE3 R-MMU-202174 https://reactome.org/PathwayBrowser/#/R-MMU-202174 Activation of ZAP-70 IEA Mus musculus A0A0A6YYE3 R-MMU-202214 https://reactome.org/PathwayBrowser/#/R-MMU-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Mus musculus A0A0A6YYE3 R-MMU-202216 https://reactome.org/PathwayBrowser/#/R-MMU-202216 Phosphorylation of SLP-76 IEA Mus musculus A0A0A6YYE3 R-MMU-202233 https://reactome.org/PathwayBrowser/#/R-MMU-202233 Inactivation of Lck by Csk IEA Mus musculus A0A0A6YYE3 R-MMU-202245 https://reactome.org/PathwayBrowser/#/R-MMU-202245 Phosphorylation of TBSMs in LAT IEA Mus musculus A0A0A6YYE3 R-MMU-202248 https://reactome.org/PathwayBrowser/#/R-MMU-202248 Phosphorylation of PLC-gamma1 IEA Mus musculus A0A0A6YYE3 R-MMU-202291 https://reactome.org/PathwayBrowser/#/R-MMU-202291 Activation of Lck IEA Mus musculus A0A0A6YYE3 R-MMU-202307 https://reactome.org/PathwayBrowser/#/R-MMU-202307 Change of PKC theta conformation IEA Mus musculus A0A0A6YYE3 R-MMU-202344 https://reactome.org/PathwayBrowser/#/R-MMU-202344 Recruitment of ZAP-70 to phosphorylated ITAMs IEA Mus musculus A0A0A6YYE3 R-MMU-389758 https://reactome.org/PathwayBrowser/#/R-MMU-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Mus musculus A0A0A6YYE3 R-MMU-8850326 https://reactome.org/PathwayBrowser/#/R-MMU-8850326 TCR binds self-lipid-based antigen via CD1 IEA Mus musculus A0A0A6YYE3 R-MMU-8850356 https://reactome.org/PathwayBrowser/#/R-MMU-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Mus musculus A0A0A6YYE3 R-MMU-8852200 https://reactome.org/PathwayBrowser/#/R-MMU-8852200 Inactivation of LCK by PTPN22 IEA Mus musculus A0A0A6YYE3 R-MMU-8855381 https://reactome.org/PathwayBrowser/#/R-MMU-8855381 PTPN22 dephosphorylates ZAP70 IEA Mus musculus A0A0A6YYK7 R-HSA-198955 https://reactome.org/PathwayBrowser/#/R-HSA-198955 TCR complex interacts with peptide antigen-presenting MHC Class I TAS Homo sapiens A0A0A6YYK7 R-HSA-202165 https://reactome.org/PathwayBrowser/#/R-HSA-202165 Phosphorylation of ITAM motifs in CD3 complexes TAS Homo sapiens A0A0A6YYK7 R-HSA-202168 https://reactome.org/PathwayBrowser/#/R-HSA-202168 Phosphorylation of ZAP-70 by Lck TAS Homo sapiens A0A0A6YYK7 R-HSA-202174 https://reactome.org/PathwayBrowser/#/R-HSA-202174 Activation of ZAP-70 TAS Homo sapiens A0A0A6YYK7 R-HSA-202214 https://reactome.org/PathwayBrowser/#/R-HSA-202214 Dephosphorylation of Lck-pY505 by CD45 TAS Homo sapiens A0A0A6YYK7 R-HSA-202216 https://reactome.org/PathwayBrowser/#/R-HSA-202216 Phosphorylation of SLP-76 TAS Homo sapiens A0A0A6YYK7 R-HSA-202233 https://reactome.org/PathwayBrowser/#/R-HSA-202233 Inactivation of Lck by Csk TAS Homo sapiens A0A0A6YYK7 R-HSA-202245 https://reactome.org/PathwayBrowser/#/R-HSA-202245 Phosphorylation of TBSMs in LAT TAS Homo sapiens A0A0A6YYK7 R-HSA-202248 https://reactome.org/PathwayBrowser/#/R-HSA-202248 Phosphorylation of PLC-gamma1 TAS Homo sapiens A0A0A6YYK7 R-HSA-202291 https://reactome.org/PathwayBrowser/#/R-HSA-202291 Activation of Lck TAS Homo sapiens A0A0A6YYK7 R-HSA-202307 https://reactome.org/PathwayBrowser/#/R-HSA-202307 Change of PKC theta conformation TAS Homo sapiens A0A0A6YYK7 R-HSA-202344 https://reactome.org/PathwayBrowser/#/R-HSA-202344 Recruitment of ZAP-70 to phosphorylated ITAMs TAS Homo sapiens A0A0A6YYK7 R-HSA-389758 https://reactome.org/PathwayBrowser/#/R-HSA-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases TAS Homo sapiens A0A0A6YYK7 R-HSA-8850326 https://reactome.org/PathwayBrowser/#/R-HSA-8850326 TCR binds self-lipid-based antigen via CD1 TAS Homo sapiens A0A0A6YYK7 R-HSA-8850356 https://reactome.org/PathwayBrowser/#/R-HSA-8850356 TCR binds microbial lipid-based antigen via CD1 TAS Homo sapiens A0A0A6YYK7 R-HSA-8852200 https://reactome.org/PathwayBrowser/#/R-HSA-8852200 Inactivation of LCK by PTPN22 TAS Homo sapiens A0A0A6YYK7 R-HSA-8855381 https://reactome.org/PathwayBrowser/#/R-HSA-8855381 PTPN22 dephosphorylates ZAP70 TAS Homo sapiens A0A0A6YYP6 R-MMU-202703 https://reactome.org/PathwayBrowser/#/R-MMU-202703 CD47 binds SIRP IEA Mus musculus A0A0A6YYP6 R-MMU-391168 https://reactome.org/PathwayBrowser/#/R-MMU-391168 SIRP gamma binds CD47 IEA Mus musculus A0A0A7H8E2 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio A0A0A7H8E2 R-DRE-388900 https://reactome.org/PathwayBrowser/#/R-DRE-388900 Neurotensin receptors can bind neurotensins IEA Danio rerio A0A0A8JC39 R-BTA-9934021 https://reactome.org/PathwayBrowser/#/R-BTA-9934021 Formation of neuronal progenitor BAF (npBAF) IEA Bos taurus A0A0A8JC39 R-BTA-9934024 https://reactome.org/PathwayBrowser/#/R-BTA-9934024 SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10 IEA Bos taurus A0A0A8JWS4 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio A0A0A8JWS4 R-DRE-391941 https://reactome.org/PathwayBrowser/#/R-DRE-391941 BLT receptors can bind LTB4 IEA Danio rerio A0A0B4J198 R-CFA-8848663 https://reactome.org/PathwayBrowser/#/R-CFA-8848663 ADIPOQ trimer binds ADIPOR dimers IEA Canis familiaris A0A0B4J199 R-CFA-109699 https://reactome.org/PathwayBrowser/#/R-CFA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Canis familiaris A0A0B4J199 R-CFA-190256 https://reactome.org/PathwayBrowser/#/R-CFA-190256 FGFR1c binds to FGF IEA Canis familiaris A0A0B4J199 R-CFA-190258 https://reactome.org/PathwayBrowser/#/R-CFA-190258 FGFR2c binds to FGF IEA Canis familiaris A0A0B4J199 R-CFA-190261 https://reactome.org/PathwayBrowser/#/R-CFA-190261 FGFR3c binds to FGF IEA Canis familiaris A0A0B4J199 R-CFA-190265 https://reactome.org/PathwayBrowser/#/R-CFA-190265 FGFR4 binds to FGF IEA Canis familiaris A0A0B4J199 R-CFA-190268 https://reactome.org/PathwayBrowser/#/R-CFA-190268 FGFR1c binds to Klotho-bound FGF23 IEA Canis familiaris A0A0B4J199 R-CFA-190326 https://reactome.org/PathwayBrowser/#/R-CFA-190326 Autocatalytic phosphorylation of FGFR4 IEA Canis familiaris A0A0B4J199 R-CFA-190388 https://reactome.org/PathwayBrowser/#/R-CFA-190388 Autocatalytic phosphorylation of FGFR3c IEA Canis familiaris A0A0B4J199 R-CFA-190413 https://reactome.org/PathwayBrowser/#/R-CFA-190413 Autocatalytic phosphorylation of FGFR2c IEA Canis familiaris A0A0B4J199 R-CFA-190429 https://reactome.org/PathwayBrowser/#/R-CFA-190429 Autocatalytic phosphorylation of FGFR1c IEA Canis familiaris A0A0B4J199 R-CFA-191062 https://reactome.org/PathwayBrowser/#/R-CFA-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Canis familiaris A0A0B4J199 R-CFA-2316434 https://reactome.org/PathwayBrowser/#/R-CFA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris A0A0B4J199 R-CFA-5654147 https://reactome.org/PathwayBrowser/#/R-CFA-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Canis familiaris A0A0B4J199 R-CFA-5654148 https://reactome.org/PathwayBrowser/#/R-CFA-5654148 p-4Y-PLCG1 dissociates from activated FGFR3 IEA Canis familiaris A0A0B4J199 R-CFA-5654149 https://reactome.org/PathwayBrowser/#/R-CFA-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Canis familiaris A0A0B4J199 R-CFA-5654151 https://reactome.org/PathwayBrowser/#/R-CFA-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Canis familiaris A0A0B4J199 R-CFA-5654157 https://reactome.org/PathwayBrowser/#/R-CFA-5654157 p-4Y-PLCG1 dissociates from activated FGFR2 IEA Canis familiaris A0A0B4J199 R-CFA-5654159 https://reactome.org/PathwayBrowser/#/R-CFA-5654159 Activated FGFR2 binds PLCG1 IEA Canis familiaris A0A0B4J199 R-CFA-5654163 https://reactome.org/PathwayBrowser/#/R-CFA-5654163 Activated FGFR4 binds PLCG1 IEA Canis familiaris A0A0B4J199 R-CFA-5654165 https://reactome.org/PathwayBrowser/#/R-CFA-5654165 p-4Y-PLCG1 dissociates from activated FGFR1 IEA Canis familiaris A0A0B4J199 R-CFA-5654167 https://reactome.org/PathwayBrowser/#/R-CFA-5654167 Activated FGFR1 binds PLCG1 IEA Canis familiaris A0A0B4J199 R-CFA-5654169 https://reactome.org/PathwayBrowser/#/R-CFA-5654169 p-4Y-PLCG1 dissociates from activated FGFR4 IEA Canis familiaris A0A0B4J199 R-CFA-5654222 https://reactome.org/PathwayBrowser/#/R-CFA-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Canis familiaris A0A0B4J199 R-CFA-5654224 https://reactome.org/PathwayBrowser/#/R-CFA-5654224 Activated FGFR3 binds PLCG1 IEA Canis familiaris A0A0B4J199 R-CFA-5654392 https://reactome.org/PathwayBrowser/#/R-CFA-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris A0A0B4J199 R-CFA-5654397 https://reactome.org/PathwayBrowser/#/R-CFA-5654397 Activated FGFR2 phosphorylates FRS2 IEA Canis familiaris A0A0B4J199 R-CFA-5654399 https://reactome.org/PathwayBrowser/#/R-CFA-5654399 Activated FGFR2 binds FRS2 IEA Canis familiaris A0A0B4J199 R-CFA-5654402 https://reactome.org/PathwayBrowser/#/R-CFA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris A0A0B4J199 R-CFA-5654404 https://reactome.org/PathwayBrowser/#/R-CFA-5654404 Activated FGFR2 binds SHC1 IEA Canis familiaris A0A0B4J199 R-CFA-5654406 https://reactome.org/PathwayBrowser/#/R-CFA-5654406 Activated FGFR2:p-SHC1 binds GRB2:SOS1 IEA Canis familiaris A0A0B4J199 R-CFA-5654407 https://reactome.org/PathwayBrowser/#/R-CFA-5654407 Activated FGFR2 phosphorylates SHC1 IEA Canis familiaris A0A0B4J199 R-CFA-5654408 https://reactome.org/PathwayBrowser/#/R-CFA-5654408 Activated FGFR3 phosphorylates FRS2 IEA Canis familiaris A0A0B4J199 R-CFA-5654409 https://reactome.org/PathwayBrowser/#/R-CFA-5654409 Activated FGFR3 binds FRS2 IEA Canis familiaris A0A0B4J199 R-CFA-5654413 https://reactome.org/PathwayBrowser/#/R-CFA-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris A0A0B4J199 R-CFA-5654416 https://reactome.org/PathwayBrowser/#/R-CFA-5654416 Activated FGFR3:pFRS binds GRB2:SOS1 IEA Canis familiaris A0A0B4J199 R-CFA-5654418 https://reactome.org/PathwayBrowser/#/R-CFA-5654418 Activated FGFR4 phosphorylates FRS2 IEA Canis familiaris A0A0B4J199 R-CFA-5654422 https://reactome.org/PathwayBrowser/#/R-CFA-5654422 Activated FGFR4 binds FRS2 IEA Canis familiaris A0A0B4J199 R-CFA-5654423 https://reactome.org/PathwayBrowser/#/R-CFA-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Canis familiaris A0A0B4J199 R-CFA-5654425 https://reactome.org/PathwayBrowser/#/R-CFA-5654425 Activated FGFR4 binds SHC1 IEA Canis familiaris A0A0B4J199 R-CFA-5654426 https://reactome.org/PathwayBrowser/#/R-CFA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris A0A0B4J199 R-CFA-5654428 https://reactome.org/PathwayBrowser/#/R-CFA-5654428 Activated FGFR4 phosphorylates SHC1 IEA Canis familiaris A0A0B4J199 R-CFA-5654511 https://reactome.org/PathwayBrowser/#/R-CFA-5654511 FGFRL1 dimer binds FGFs IEA Canis familiaris A0A0B4J199 R-CFA-5654560 https://reactome.org/PathwayBrowser/#/R-CFA-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2 IEA Canis familiaris A0A0B4J199 R-CFA-5654562 https://reactome.org/PathwayBrowser/#/R-CFA-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Canis familiaris A0A0B4J199 R-CFA-5654565 https://reactome.org/PathwayBrowser/#/R-CFA-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2 IEA Canis familiaris A0A0B4J199 R-CFA-5654566 https://reactome.org/PathwayBrowser/#/R-CFA-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2 IEA Canis familiaris A0A0B4J199 R-CFA-5654569 https://reactome.org/PathwayBrowser/#/R-CFA-5654569 Activated FGFR1 binds FRS2 IEA Canis familiaris A0A0B4J199 R-CFA-5654571 https://reactome.org/PathwayBrowser/#/R-CFA-5654571 Activated FGFR1 binds FRS3 IEA Canis familiaris A0A0B4J199 R-CFA-5654573 https://reactome.org/PathwayBrowser/#/R-CFA-5654573 Activated FGFR1 binds SHC1 IEA Canis familiaris A0A0B4J199 R-CFA-5654575 https://reactome.org/PathwayBrowser/#/R-CFA-5654575 Activated FGFR1 phosphorylates FRS2 IEA Canis familiaris A0A0B4J199 R-CFA-5654578 https://reactome.org/PathwayBrowser/#/R-CFA-5654578 Activated FGFR1 phosphorylates FRS3 IEA Canis familiaris A0A0B4J199 R-CFA-5654582 https://reactome.org/PathwayBrowser/#/R-CFA-5654582 Activated FGFR1 phosphorylates SHC1 IEA Canis familiaris A0A0B4J199 R-CFA-5654584 https://reactome.org/PathwayBrowser/#/R-CFA-5654584 Activated FGFR1:p-FRS bind to PPTN11 IEA Canis familiaris A0A0B4J199 R-CFA-5654586 https://reactome.org/PathwayBrowser/#/R-CFA-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Canis familiaris A0A0B4J199 R-CFA-5654587 https://reactome.org/PathwayBrowser/#/R-CFA-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Canis familiaris A0A0B4J199 R-CFA-5654591 https://reactome.org/PathwayBrowser/#/R-CFA-5654591 Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Canis familiaris A0A0B4J199 R-CFA-5654592 https://reactome.org/PathwayBrowser/#/R-CFA-5654592 Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Canis familiaris A0A0B4J199 R-CFA-5654594 https://reactome.org/PathwayBrowser/#/R-CFA-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Canis familiaris A0A0B4J199 R-CFA-5654596 https://reactome.org/PathwayBrowser/#/R-CFA-5654596 Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Canis familiaris A0A0B4J199 R-CFA-5654597 https://reactome.org/PathwayBrowser/#/R-CFA-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Canis familiaris A0A0B4J199 R-CFA-5654600 https://reactome.org/PathwayBrowser/#/R-CFA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris A0A0B4J199 R-CFA-5654603 https://reactome.org/PathwayBrowser/#/R-CFA-5654603 Activated FGFR2 binds FRS3 IEA Canis familiaris A0A0B4J199 R-CFA-5654605 https://reactome.org/PathwayBrowser/#/R-CFA-5654605 Activated FGFR2 phosphorylates FRS3 IEA Canis familiaris A0A0B4J199 R-CFA-5654607 https://reactome.org/PathwayBrowser/#/R-CFA-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Canis familiaris A0A0B4J199 R-CFA-5654608 https://reactome.org/PathwayBrowser/#/R-CFA-5654608 Activated FGFR2:p-FRS bind to PPTN11 IEA Canis familiaris A0A0B4J199 R-CFA-5654612 https://reactome.org/PathwayBrowser/#/R-CFA-5654612 Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Canis familiaris A0A0B4J199 R-CFA-5654614 https://reactome.org/PathwayBrowser/#/R-CFA-5654614 Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Canis familiaris A0A0B4J199 R-CFA-5654615 https://reactome.org/PathwayBrowser/#/R-CFA-5654615 Activated FGFR2:pFRS binds GRB2:SOS1 IEA Canis familiaris A0A0B4J199 R-CFA-5654618 https://reactome.org/PathwayBrowser/#/R-CFA-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris A0A0B4J199 R-CFA-5654620 https://reactome.org/PathwayBrowser/#/R-CFA-5654620 Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Canis familiaris A0A0B4J199 R-CFA-5654622 https://reactome.org/PathwayBrowser/#/R-CFA-5654622 Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Canis familiaris A0A0B4J199 R-CFA-5654623 https://reactome.org/PathwayBrowser/#/R-CFA-5654623 Activated FGFR3 binds FRS3 IEA Canis familiaris A0A0B4J199 R-CFA-5654625 https://reactome.org/PathwayBrowser/#/R-CFA-5654625 Activated FGFR3 binds SHC1 IEA Canis familiaris A0A0B4J199 R-CFA-5654628 https://reactome.org/PathwayBrowser/#/R-CFA-5654628 Activated FGFR3 phosphorylates FRS3 IEA Canis familiaris A0A0B4J199 R-CFA-5654631 https://reactome.org/PathwayBrowser/#/R-CFA-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Canis familiaris A0A0B4J199 R-CFA-5654633 https://reactome.org/PathwayBrowser/#/R-CFA-5654633 Activated FGFR3:p-FRS bind to PPTN11 IEA Canis familiaris A0A0B4J199 R-CFA-5654634 https://reactome.org/PathwayBrowser/#/R-CFA-5654634 Activated FGFR3 phosphorylates SHC1 IEA Canis familiaris A0A0B4J199 R-CFA-5654637 https://reactome.org/PathwayBrowser/#/R-CFA-5654637 Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Canis familiaris A0A0B4J199 R-CFA-5654640 https://reactome.org/PathwayBrowser/#/R-CFA-5654640 Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Canis familiaris A0A0B4J199 R-CFA-5654641 https://reactome.org/PathwayBrowser/#/R-CFA-5654641 Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Canis familiaris A0A0B4J199 R-CFA-5654643 https://reactome.org/PathwayBrowser/#/R-CFA-5654643 Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Canis familiaris A0A0B4J199 R-CFA-5654646 https://reactome.org/PathwayBrowser/#/R-CFA-5654646 Activated FGFR3:p-SHC1 binds GRB2:SOS1 IEA Canis familiaris A0A0B4J199 R-CFA-5654647 https://reactome.org/PathwayBrowser/#/R-CFA-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris A0A0B4J199 R-CFA-5654651 https://reactome.org/PathwayBrowser/#/R-CFA-5654651 Activated FGFR4 binds FRS3 IEA Canis familiaris A0A0B4J199 R-CFA-5654653 https://reactome.org/PathwayBrowser/#/R-CFA-5654653 Activated FGFR4 phosphorylates FRS3 IEA Canis familiaris A0A0B4J199 R-CFA-5654655 https://reactome.org/PathwayBrowser/#/R-CFA-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Canis familiaris A0A0B4J199 R-CFA-5654658 https://reactome.org/PathwayBrowser/#/R-CFA-5654658 Activated FGFR4:p-FRS bind to PPTN11 IEA Canis familiaris A0A0B4J199 R-CFA-5654659 https://reactome.org/PathwayBrowser/#/R-CFA-5654659 Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Canis familiaris A0A0B4J199 R-CFA-5654662 https://reactome.org/PathwayBrowser/#/R-CFA-5654662 Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Canis familiaris A0A0B4J199 R-CFA-5654663 https://reactome.org/PathwayBrowser/#/R-CFA-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Canis familiaris A0A0B4J199 R-CFA-5654664 https://reactome.org/PathwayBrowser/#/R-CFA-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Canis familiaris A0A0B4J199 R-CFA-5654667 https://reactome.org/PathwayBrowser/#/R-CFA-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Canis familiaris A0A0B4J199 R-CFA-5654669 https://reactome.org/PathwayBrowser/#/R-CFA-5654669 Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA IEA Canis familiaris A0A0B4J199 R-CFA-5654672 https://reactome.org/PathwayBrowser/#/R-CFA-5654672 CBL ubiquitinates FRS2 and FGFR1 IEA Canis familiaris A0A0B4J199 R-CFA-5654673 https://reactome.org/PathwayBrowser/#/R-CFA-5654673 p-CBL:GRB2 binds p-FRS2:activated FGFR1 IEA Canis familiaris A0A0B4J199 R-CFA-5654677 https://reactome.org/PathwayBrowser/#/R-CFA-5654677 CBL ubiquitinates FRS2 and FGFR2 IEA Canis familiaris A0A0B4J199 R-CFA-5654679 https://reactome.org/PathwayBrowser/#/R-CFA-5654679 CBL ubiquitinates FRS2 and FGFR3 IEA Canis familiaris A0A0B4J199 R-CFA-5654684 https://reactome.org/PathwayBrowser/#/R-CFA-5654684 CBL ubiquitinates FRS2 and FGFR4 IEA Canis familiaris A0A0B4J199 R-CFA-5654690 https://reactome.org/PathwayBrowser/#/R-CFA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris A0A0B4J199 R-CFA-5654692 https://reactome.org/PathwayBrowser/#/R-CFA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris A0A0B4J199 R-CFA-5654697 https://reactome.org/PathwayBrowser/#/R-CFA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris A0A0B4J199 R-CFA-5654701 https://reactome.org/PathwayBrowser/#/R-CFA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris A0A0B4J199 R-CFA-5654705 https://reactome.org/PathwayBrowser/#/R-CFA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris A0A0B4J199 R-CFA-5654709 https://reactome.org/PathwayBrowser/#/R-CFA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris A0A0B4J199 R-CFA-5654714 https://reactome.org/PathwayBrowser/#/R-CFA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris A0A0B4J199 R-CFA-5654717 https://reactome.org/PathwayBrowser/#/R-CFA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Canis familiaris A0A0B4J199 R-CFA-5654729 https://reactome.org/PathwayBrowser/#/R-CFA-5654729 p-CBL:GRB2 binds p-FRS2:activated FGFR2 IEA Canis familiaris A0A0B4J199 R-CFA-5654730 https://reactome.org/PathwayBrowser/#/R-CFA-5654730 p-CBL:GRB2 binds p-FRS2:activated FGFR3 IEA Canis familiaris A0A0B4J199 R-CFA-5654734 https://reactome.org/PathwayBrowser/#/R-CFA-5654734 p-CBL:GRB2 binds p-FRS2:activated FGFR4 IEA Canis familiaris A0A0B4J199 R-CFA-5656064 https://reactome.org/PathwayBrowser/#/R-CFA-5656064 Activated FGFR1 binds FLRT1,2,3 IEA Canis familiaris A0A0B4J199 R-CFA-5672965 https://reactome.org/PathwayBrowser/#/R-CFA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Canis familiaris A0A0B4J199 R-CFA-8851619 https://reactome.org/PathwayBrowser/#/R-CFA-8851619 GALNT3 transfers GalNAc to FGF23 IEA Canis familiaris A0A0B4J199 R-CFA-8851632 https://reactome.org/PathwayBrowser/#/R-CFA-8851632 GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region IEA Canis familiaris A0A0B4J199 R-CFA-8941613 https://reactome.org/PathwayBrowser/#/R-CFA-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Canis familiaris A0A0B4J199 R-CFA-8941618 https://reactome.org/PathwayBrowser/#/R-CFA-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Canis familiaris A0A0B4J199 R-CFA-8941623 https://reactome.org/PathwayBrowser/#/R-CFA-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Canis familiaris A0A0B4J199 R-CFA-8941628 https://reactome.org/PathwayBrowser/#/R-CFA-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Canis familiaris A0A0B4J199 R-CFA-8952289 https://reactome.org/PathwayBrowser/#/R-CFA-8952289 FAM20C phosphorylates FAM20C substrates IEA Canis familiaris A0A0B4J1F3 R-MMU-6798743 https://reactome.org/PathwayBrowser/#/R-MMU-6798743 Exocytosis of secretory granule membrane proteins IEA Mus musculus A0A0B4J1F3 R-MMU-6798747 https://reactome.org/PathwayBrowser/#/R-MMU-6798747 Exocytosis of tertiary granule membrane proteins IEA Mus musculus A0A0B4J1F3 R-MMU-6799350 https://reactome.org/PathwayBrowser/#/R-MMU-6799350 Exocytosis of specific granule membrane proteins IEA Mus musculus A0A0B4J1F3 R-MMU-6800426 https://reactome.org/PathwayBrowser/#/R-MMU-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Mus musculus A0A0B4J1F9 R-MMU-6810937 https://reactome.org/PathwayBrowser/#/R-MMU-6810937 Lamellar bodies bind the early cornified envelope IEA Mus musculus A0A0B4J1F9 R-MMU-6814387 https://reactome.org/PathwayBrowser/#/R-MMU-6814387 CASP14 cleaves filaggrin IEA Mus musculus A0A0B4J1F9 R-MMU-6814734 https://reactome.org/PathwayBrowser/#/R-MMU-6814734 CDSN binds the cornified envelope IEA Mus musculus A0A0B4J1F9 R-MMU-6814764 https://reactome.org/PathwayBrowser/#/R-MMU-6814764 Plasma membrane resorption IEA Mus musculus A0A0B4J1G0 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A0B4J1G0 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A0B4J1G0 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A0B4J1G0 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A0B4J1G0 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A0B4J1G0 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A0B4J1G0 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A0B4J1G0 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A0B4J1G0 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A0B4J1G0 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A0B4J1G0 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A0B4J1G0 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A0B4J1G0 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A0B4J1G0 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A0B4J1G0 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A0B4J1G0 R-MMU-6798743 https://reactome.org/PathwayBrowser/#/R-MMU-6798743 Exocytosis of secretory granule membrane proteins IEA Mus musculus A0A0B4J1G0 R-MMU-8940388 https://reactome.org/PathwayBrowser/#/R-MMU-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Mus musculus A0A0B4J1H3 R-MMU-198955 https://reactome.org/PathwayBrowser/#/R-MMU-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Mus musculus A0A0B4J1H3 R-MMU-202165 https://reactome.org/PathwayBrowser/#/R-MMU-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Mus musculus A0A0B4J1H3 R-MMU-202168 https://reactome.org/PathwayBrowser/#/R-MMU-202168 Phosphorylation of ZAP-70 by Lck IEA Mus musculus A0A0B4J1H3 R-MMU-202174 https://reactome.org/PathwayBrowser/#/R-MMU-202174 Activation of ZAP-70 IEA Mus musculus A0A0B4J1H3 R-MMU-202214 https://reactome.org/PathwayBrowser/#/R-MMU-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Mus musculus A0A0B4J1H3 R-MMU-202216 https://reactome.org/PathwayBrowser/#/R-MMU-202216 Phosphorylation of SLP-76 IEA Mus musculus A0A0B4J1H3 R-MMU-202233 https://reactome.org/PathwayBrowser/#/R-MMU-202233 Inactivation of Lck by Csk IEA Mus musculus A0A0B4J1H3 R-MMU-202245 https://reactome.org/PathwayBrowser/#/R-MMU-202245 Phosphorylation of TBSMs in LAT IEA Mus musculus A0A0B4J1H3 R-MMU-202248 https://reactome.org/PathwayBrowser/#/R-MMU-202248 Phosphorylation of PLC-gamma1 IEA Mus musculus A0A0B4J1H3 R-MMU-202291 https://reactome.org/PathwayBrowser/#/R-MMU-202291 Activation of Lck IEA Mus musculus A0A0B4J1H3 R-MMU-202307 https://reactome.org/PathwayBrowser/#/R-MMU-202307 Change of PKC theta conformation IEA Mus musculus A0A0B4J1H3 R-MMU-202344 https://reactome.org/PathwayBrowser/#/R-MMU-202344 Recruitment of ZAP-70 to phosphorylated ITAMs IEA Mus musculus A0A0B4J1H3 R-MMU-389758 https://reactome.org/PathwayBrowser/#/R-MMU-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Mus musculus A0A0B4J1H3 R-MMU-8850326 https://reactome.org/PathwayBrowser/#/R-MMU-8850326 TCR binds self-lipid-based antigen via CD1 IEA Mus musculus A0A0B4J1H3 R-MMU-8850356 https://reactome.org/PathwayBrowser/#/R-MMU-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Mus musculus A0A0B4J1H3 R-MMU-8852200 https://reactome.org/PathwayBrowser/#/R-MMU-8852200 Inactivation of LCK by PTPN22 IEA Mus musculus A0A0B4J1H3 R-MMU-8855381 https://reactome.org/PathwayBrowser/#/R-MMU-8855381 PTPN22 dephosphorylates ZAP70 IEA Mus musculus A0A0B4J1H6 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A0B4J1H6 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A0B4J1H6 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A0B4J1H6 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A0B4J1H6 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A0B4J1H6 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A0B4J1H6 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A0B4J1H6 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A0B4J1H6 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A0B4J1H6 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A0B4J1H6 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A0B4J1H6 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A0B4J1H6 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A0B4J1H6 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A0B4J1H6 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A0B4J1H6 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A0B4J1H6 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A0B4J1H6 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A0B4J1H6 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A0B4J1H6 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A0B4J1H6 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A0B4J1H6 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A0B4J1H6 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A0B4J1H6 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A0B4J1H6 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A0B4J1H6 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A0B4J1H6 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A0B4J1H6 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A0B4J1H6 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A0B4J1H6 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A0B4J1H6 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A0B4J1H6 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A0B4J1H6 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A0B4J1H6 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A0B4J1H6 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A0B4J1H6 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A0B4J1H6 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A0B4J1H6 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A0B4J1H6 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A0B4J1H6 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A0B4J1H6 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A0B4J1H6 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A0B4J1H6 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A0B4J1H6 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A0B4J1H6 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A0B4J1H6 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A0B4J1H6 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A0B4J1H7 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A0B4J1H7 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A0B4J1H7 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A0B4J1H7 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A0B4J1H7 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A0B4J1H7 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A0B4J1H7 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A0B4J1H7 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A0B4J1H7 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A0B4J1H7 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A0B4J1H7 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A0B4J1H7 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A0B4J1H7 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A0B4J1H7 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A0B4J1H7 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A0B4J1H7 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A0B4J1H7 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A0B4J1H7 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A0B4J1H7 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A0B4J1H7 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A0B4J1H7 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A0B4J1H7 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A0B4J1H7 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A0B4J1H7 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A0B4J1H7 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A0B4J1H7 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A0B4J1H7 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A0B4J1H7 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A0B4J1H7 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A0B4J1H7 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A0B4J1H7 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A0B4J1H7 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A0B4J1H7 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A0B4J1H7 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A0B4J1H7 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A0B4J1H7 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A0B4J1H7 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A0B4J1H7 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A0B4J1H7 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A0B4J1H7 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A0B4J1H7 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A0B4J1H7 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A0B4J1H7 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A0B4J1H7 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A0B4J1H7 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A0B4J1H7 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A0B4J1H7 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A0B4J1H8 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A0B4J1H8 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A0B4J1H8 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A0B4J1H8 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A0B4J1H8 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A0B4J1H8 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A0B4J1H8 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A0B4J1H8 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A0B4J1H8 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A0B4J1H8 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A0B4J1H8 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A0B4J1H8 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A0B4J1H8 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A0B4J1H8 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A0B4J1H8 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A0B4J1H8 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A0B4J1H8 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A0B4J1H8 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A0B4J1H8 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A0B4J1H8 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A0B4J1H8 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A0B4J1H8 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A0B4J1H8 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A0B4J1H8 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A0B4J1H8 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A0B4J1H8 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A0B4J1H8 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A0B4J1H8 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A0B4J1H8 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A0B4J1H8 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A0B4J1H8 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A0B4J1H8 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A0B4J1H8 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A0B4J1H8 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A0B4J1H8 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A0B4J1H8 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A0B4J1H8 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A0B4J1H8 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A0B4J1H8 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A0B4J1H8 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A0B4J1H8 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A0B4J1H8 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A0B4J1H8 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A0B4J1H8 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A0B4J1H8 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A0B4J1H8 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A0B4J1H8 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A0B4J1H9 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A0B4J1H9 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A0B4J1H9 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A0B4J1H9 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A0B4J1H9 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A0B4J1H9 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A0B4J1H9 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A0B4J1H9 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A0B4J1H9 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A0B4J1H9 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A0B4J1H9 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A0B4J1H9 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A0B4J1H9 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A0B4J1H9 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A0B4J1H9 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A0B4J1H9 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A0B4J1H9 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A0B4J1H9 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A0B4J1H9 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A0B4J1H9 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A0B4J1H9 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A0B4J1H9 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A0B4J1H9 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A0B4J1H9 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A0B4J1H9 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A0B4J1H9 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A0B4J1H9 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A0B4J1H9 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A0B4J1H9 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A0B4J1H9 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A0B4J1H9 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A0B4J1H9 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A0B4J1H9 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A0B4J1H9 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A0B4J1H9 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A0B4J1H9 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A0B4J1H9 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A0B4J1H9 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A0B4J1H9 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A0B4J1H9 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A0B4J1H9 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A0B4J1H9 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A0B4J1H9 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A0B4J1H9 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A0B4J1H9 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A0B4J1H9 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A0B4J1H9 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A0B4J1I0 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A0B4J1I0 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A0B4J1I0 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A0B4J1I0 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A0B4J1I0 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A0B4J1I0 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A0B4J1I0 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A0B4J1I0 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A0B4J1I0 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A0B4J1I0 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A0B4J1I0 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A0B4J1I0 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A0B4J1I0 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A0B4J1I0 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A0B4J1I0 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A0B4J1I0 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A0B4J1I0 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A0B4J1I0 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A0B4J1I0 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A0B4J1I0 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A0B4J1I0 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A0B4J1I0 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A0B4J1I0 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A0B4J1I0 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A0B4J1I0 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A0B4J1I0 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A0B4J1I0 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A0B4J1I0 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A0B4J1I0 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A0B4J1I0 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A0B4J1I0 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A0B4J1I0 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A0B4J1I0 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A0B4J1I0 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A0B4J1I0 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A0B4J1I0 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A0B4J1I0 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A0B4J1I0 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A0B4J1I0 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A0B4J1I0 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A0B4J1I0 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A0B4J1I0 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A0B4J1I0 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A0B4J1I0 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A0B4J1I0 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A0B4J1I0 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A0B4J1I0 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A0B4J1I1 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A0B4J1I1 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A0B4J1I1 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A0B4J1I1 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A0B4J1I1 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A0B4J1I1 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A0B4J1I1 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A0B4J1I1 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A0B4J1I1 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A0B4J1I1 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A0B4J1I1 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A0B4J1I1 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A0B4J1I1 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A0B4J1I1 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A0B4J1I1 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A0B4J1I1 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A0B4J1I1 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A0B4J1I1 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A0B4J1I1 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A0B4J1I1 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A0B4J1I1 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A0B4J1I1 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A0B4J1I1 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A0B4J1I1 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A0B4J1I1 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A0B4J1I1 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A0B4J1I1 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A0B4J1I1 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A0B4J1I1 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A0B4J1I1 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A0B4J1I1 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A0B4J1I1 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A0B4J1I1 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A0B4J1I1 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A0B4J1I1 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A0B4J1I1 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A0B4J1I1 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A0B4J1I1 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A0B4J1I1 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A0B4J1I1 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A0B4J1I1 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A0B4J1I1 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A0B4J1I1 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A0B4J1I1 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A0B4J1I1 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A0B4J1I1 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A0B4J1I1 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A0B4J1K4 R-MMU-198955 https://reactome.org/PathwayBrowser/#/R-MMU-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Mus musculus A0A0B4J1K4 R-MMU-202165 https://reactome.org/PathwayBrowser/#/R-MMU-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Mus musculus A0A0B4J1K4 R-MMU-202168 https://reactome.org/PathwayBrowser/#/R-MMU-202168 Phosphorylation of ZAP-70 by Lck IEA Mus musculus A0A0B4J1K4 R-MMU-202174 https://reactome.org/PathwayBrowser/#/R-MMU-202174 Activation of ZAP-70 IEA Mus musculus A0A0B4J1K4 R-MMU-202214 https://reactome.org/PathwayBrowser/#/R-MMU-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Mus musculus A0A0B4J1K4 R-MMU-202216 https://reactome.org/PathwayBrowser/#/R-MMU-202216 Phosphorylation of SLP-76 IEA Mus musculus A0A0B4J1K4 R-MMU-202233 https://reactome.org/PathwayBrowser/#/R-MMU-202233 Inactivation of Lck by Csk IEA Mus musculus A0A0B4J1K4 R-MMU-202245 https://reactome.org/PathwayBrowser/#/R-MMU-202245 Phosphorylation of TBSMs in LAT IEA Mus musculus A0A0B4J1K4 R-MMU-202248 https://reactome.org/PathwayBrowser/#/R-MMU-202248 Phosphorylation of PLC-gamma1 IEA Mus musculus A0A0B4J1K4 R-MMU-202291 https://reactome.org/PathwayBrowser/#/R-MMU-202291 Activation of Lck IEA Mus musculus A0A0B4J1K4 R-MMU-202307 https://reactome.org/PathwayBrowser/#/R-MMU-202307 Change of PKC theta conformation IEA Mus musculus A0A0B4J1K4 R-MMU-202344 https://reactome.org/PathwayBrowser/#/R-MMU-202344 Recruitment of ZAP-70 to phosphorylated ITAMs IEA Mus musculus A0A0B4J1K4 R-MMU-389758 https://reactome.org/PathwayBrowser/#/R-MMU-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Mus musculus A0A0B4J1K4 R-MMU-8850326 https://reactome.org/PathwayBrowser/#/R-MMU-8850326 TCR binds self-lipid-based antigen via CD1 IEA Mus musculus A0A0B4J1K4 R-MMU-8850356 https://reactome.org/PathwayBrowser/#/R-MMU-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Mus musculus A0A0B4J1K4 R-MMU-8852200 https://reactome.org/PathwayBrowser/#/R-MMU-8852200 Inactivation of LCK by PTPN22 IEA Mus musculus A0A0B4J1K4 R-MMU-8855381 https://reactome.org/PathwayBrowser/#/R-MMU-8855381 PTPN22 dephosphorylates ZAP70 IEA Mus musculus A0A0B4J2J0 R-RNO-1236940 https://reactome.org/PathwayBrowser/#/R-RNO-1236940 Exogenous soluble antigen targeted to more stable early endosome IEA Rattus norvegicus A0A0B4J2J0 R-RNO-1236941 https://reactome.org/PathwayBrowser/#/R-RNO-1236941 Internalization of receptor bound antigen into clathrin coted vesicles IEA Rattus norvegicus A0A0B4J2J0 R-RNO-1236955 https://reactome.org/PathwayBrowser/#/R-RNO-1236955 Movement of clathrin coated vesicles into early endosome IEA Rattus norvegicus A0A0B4J2J0 R-RNO-2029268 https://reactome.org/PathwayBrowser/#/R-RNO-2029268 Phosphorylation and activation of PLCG IEA Rattus norvegicus A0A0B4J2J0 R-RNO-2029270 https://reactome.org/PathwayBrowser/#/R-RNO-2029270 Recruitment of PLCgamma to membrane IEA Rattus norvegicus A0A0B4J2J0 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0B4J2J0 R-RNO-2029272 https://reactome.org/PathwayBrowser/#/R-RNO-2029272 Release of PLCG from FCGR IEA Rattus norvegicus A0A0B4J2J0 R-RNO-2029273 https://reactome.org/PathwayBrowser/#/R-RNO-2029273 PI3K binds to p-6Y-SYK IEA Rattus norvegicus A0A0B4J2J0 R-RNO-2029451 https://reactome.org/PathwayBrowser/#/R-RNO-2029451 Activation of RAC1 by VAV IEA Rattus norvegicus A0A0B4J2J0 R-RNO-2029452 https://reactome.org/PathwayBrowser/#/R-RNO-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Rattus norvegicus A0A0B4J2J0 R-RNO-2029453 https://reactome.org/PathwayBrowser/#/R-RNO-2029453 Phosphorylation of VAV IEA Rattus norvegicus A0A0B4J2J0 R-RNO-2029455 https://reactome.org/PathwayBrowser/#/R-RNO-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Rattus norvegicus A0A0B4J2J0 R-RNO-2029458 https://reactome.org/PathwayBrowser/#/R-RNO-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Rattus norvegicus A0A0B4J2J0 R-RNO-2029459 https://reactome.org/PathwayBrowser/#/R-RNO-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Rattus norvegicus A0A0B4J2J0 R-RNO-2029467 https://reactome.org/PathwayBrowser/#/R-RNO-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Rattus norvegicus A0A0B4J2J0 R-RNO-2029476 https://reactome.org/PathwayBrowser/#/R-RNO-2029476 Role of myosins in phagosome formation IEA Rattus norvegicus A0A0B4J2J3 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A0B4J2J3 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A0B4J2J3 R-SSC-6800426 https://reactome.org/PathwayBrowser/#/R-SSC-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Sus scrofa A0A0B4J2J9 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A0B4J2J9 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A0B4J2J9 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A0B4J2J9 R-SSC-6800426 https://reactome.org/PathwayBrowser/#/R-SSC-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Sus scrofa A0A0B4JCY1 R-DME-2684901 https://reactome.org/PathwayBrowser/#/R-DME-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Drosophila melanogaster A0A0B4JCZ0 R-DME-8867876 https://reactome.org/PathwayBrowser/#/R-DME-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Drosophila melanogaster A0A0B4JDC9 R-DME-210426 https://reactome.org/PathwayBrowser/#/R-DME-210426 Glutamate synaptic vesicle docking and priming IEA Drosophila melanogaster A0A0B4JDC9 R-DME-210430 https://reactome.org/PathwayBrowser/#/R-DME-210430 Release of L-Glutamate at the synapse IEA Drosophila melanogaster A0A0B4JDC9 R-DME-372505 https://reactome.org/PathwayBrowser/#/R-DME-372505 Acetylcholine synaptic vesicle docking and priming IEA Drosophila melanogaster A0A0B4JDC9 R-DME-372529 https://reactome.org/PathwayBrowser/#/R-DME-372529 Release of acetylcholine at the synapse IEA Drosophila melanogaster A0A0B4JDC9 R-DME-374899 https://reactome.org/PathwayBrowser/#/R-DME-374899 Release of noradrenaline at the synapse IEA Drosophila melanogaster A0A0B4JDC9 R-DME-374922 https://reactome.org/PathwayBrowser/#/R-DME-374922 Noradrenalin synaptic vesicle docking and priming IEA Drosophila melanogaster A0A0B4JDC9 R-DME-380574 https://reactome.org/PathwayBrowser/#/R-DME-380574 Dopamine synaptic vesicle docking and priming IEA Drosophila melanogaster A0A0B4JDC9 R-DME-380869 https://reactome.org/PathwayBrowser/#/R-DME-380869 Release of docked dopamine loaded synaptic vesicle IEA Drosophila melanogaster A0A0B4JDC9 R-DME-380901 https://reactome.org/PathwayBrowser/#/R-DME-380901 Release of docked serotonin loaded synaptic vesicle IEA Drosophila melanogaster A0A0B4JDC9 R-DME-380905 https://reactome.org/PathwayBrowser/#/R-DME-380905 Serotonin loaded synaptic vesicle docking and priming IEA Drosophila melanogaster A0A0B4JDC9 R-DME-8951850 https://reactome.org/PathwayBrowser/#/R-DME-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane IEA Drosophila melanogaster A0A0B4K5Z8 R-DME-203979 https://reactome.org/PathwayBrowser/#/R-DME-203979 Coat Assembly IEA Drosophila melanogaster A0A0B4K5Z8 R-DME-204008 https://reactome.org/PathwayBrowser/#/R-DME-204008 SEC31:SEC13 and v-SNARE recruitment IEA Drosophila melanogaster A0A0B4K5Z8 R-DME-5694409 https://reactome.org/PathwayBrowser/#/R-DME-5694409 Nucleotide exchange on RAB1 IEA Drosophila melanogaster A0A0B4K5Z8 R-DME-5694413 https://reactome.org/PathwayBrowser/#/R-DME-5694413 SEC4C,D bind GOSR2 and STX5 IEA Drosophila melanogaster A0A0B4K5Z8 R-DME-5694415 https://reactome.org/PathwayBrowser/#/R-DME-5694415 SEC24A,B:SEC23A bind SEC22B IEA Drosophila melanogaster A0A0B4K5Z8 R-DME-5694418 https://reactome.org/PathwayBrowser/#/R-DME-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Drosophila melanogaster A0A0B4K5Z8 R-DME-5694439 https://reactome.org/PathwayBrowser/#/R-DME-5694439 COPII coat binds TRAPPCII and RAB1:GDP IEA Drosophila melanogaster A0A0B4K5Z8 R-DME-5694446 https://reactome.org/PathwayBrowser/#/R-DME-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Drosophila melanogaster A0A0B4K5Z8 R-DME-5694522 https://reactome.org/PathwayBrowser/#/R-DME-5694522 Inner coat assembly and cargo binding IEA Drosophila melanogaster A0A0B4K5Z8 R-DME-5694527 https://reactome.org/PathwayBrowser/#/R-DME-5694527 Loss of SAR1B GTPase IEA Drosophila melanogaster A0A0B4K651 R-DME-2744361 https://reactome.org/PathwayBrowser/#/R-DME-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Drosophila melanogaster A0A0B4K651 R-DME-2752067 https://reactome.org/PathwayBrowser/#/R-DME-2752067 BESTs transport cytosolic HCO3- to extracellular region IEA Drosophila melanogaster A0A0B4K657 R-DME-481044 https://reactome.org/PathwayBrowser/#/R-DME-481044 Surface deployment of platelet alpha granule membrane components IEA Drosophila melanogaster A0A0B4K657 R-DME-8854209 https://reactome.org/PathwayBrowser/#/R-DME-8854209 TBC1D10A binds JFC1 IEA Drosophila melanogaster A0A0B4K691 R-DME-2671885 https://reactome.org/PathwayBrowser/#/R-DME-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Drosophila melanogaster A0A0B4K691 R-DME-8863494 https://reactome.org/PathwayBrowser/#/R-DME-8863494 ASICs bind STOML3, (STOM) IEA Drosophila melanogaster A0A0B4K691 R-DME-9649963 https://reactome.org/PathwayBrowser/#/R-DME-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Drosophila melanogaster A0A0B4K691 R-DME-9650165 https://reactome.org/PathwayBrowser/#/R-DME-9650165 ASIC trimers bind H+ IEA Drosophila melanogaster A0A0B4K692 R-DME-2022368 https://reactome.org/PathwayBrowser/#/R-DME-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Drosophila melanogaster A0A0B4K692 R-DME-2022396 https://reactome.org/PathwayBrowser/#/R-DME-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Drosophila melanogaster A0A0B4K692 R-DME-6798743 https://reactome.org/PathwayBrowser/#/R-DME-6798743 Exocytosis of secretory granule membrane proteins IEA Drosophila melanogaster A0A0B4K692 R-DME-9727607 https://reactome.org/PathwayBrowser/#/R-DME-9727607 MME:Zn2+ binds sacubitrilat IEA Drosophila melanogaster A0A0B4K6E2 R-DME-425661 https://reactome.org/PathwayBrowser/#/R-DME-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Drosophila melanogaster A0A0B4K6E6 R-DME-163214 https://reactome.org/PathwayBrowser/#/R-DME-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Drosophila melanogaster A0A0B4K6F9 R-DME-8857662 https://reactome.org/PathwayBrowser/#/R-DME-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane IEA Drosophila melanogaster A0A0B4K6F9 R-DME-9693125 https://reactome.org/PathwayBrowser/#/R-DME-9693125 RHOF binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4K6F9 R-DME-9693198 https://reactome.org/PathwayBrowser/#/R-DME-9693198 RHOD binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4K6G5 R-DME-2872444 https://reactome.org/PathwayBrowser/#/R-DME-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Drosophila melanogaster A0A0B4K6G5 R-DME-2889070 https://reactome.org/PathwayBrowser/#/R-DME-2889070 SLC9B2 exchanges Na+ for H+ IEA Drosophila melanogaster A0A0B4K6I6 R-DME-5362522 https://reactome.org/PathwayBrowser/#/R-DME-5362522 ALDHs oxidise atRAL to atRA IEA Drosophila melanogaster A0A0B4K6I6 R-DME-5696091 https://reactome.org/PathwayBrowser/#/R-DME-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Drosophila melanogaster A0A0B4K6I6 R-DME-6813749 https://reactome.org/PathwayBrowser/#/R-DME-6813749 ALDH1A1 oxidises GA to DGA IEA Drosophila melanogaster A0A0B4K6I6 R-DME-71691 https://reactome.org/PathwayBrowser/#/R-DME-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Drosophila melanogaster A0A0B4K6I6 R-DME-9838035 https://reactome.org/PathwayBrowser/#/R-DME-9838035 CLPXP binds mitochondrial matrix proteins IEA Drosophila melanogaster A0A0B4K6I6 R-DME-9838081 https://reactome.org/PathwayBrowser/#/R-DME-9838081 LONP1 degrades mitochondrial matrix proteins IEA Drosophila melanogaster A0A0B4K6I6 R-DME-9838093 https://reactome.org/PathwayBrowser/#/R-DME-9838093 LONP1 binds mitochondrial matrix proteins IEA Drosophila melanogaster A0A0B4K6I6 R-DME-9838289 https://reactome.org/PathwayBrowser/#/R-DME-9838289 CLPXP degrades mitochondrial matrix proteins IEA Drosophila melanogaster A0A0B4K6L3 R-DME-205039 https://reactome.org/PathwayBrowser/#/R-DME-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Drosophila melanogaster A0A0B4K6L3 R-DME-419166 https://reactome.org/PathwayBrowser/#/R-DME-419166 GEFs activate RhoA,B,C IEA Drosophila melanogaster A0A0B4K6L3 R-DME-8980691 https://reactome.org/PathwayBrowser/#/R-DME-8980691 RHOA GEFs activate RHOA IEA Drosophila melanogaster A0A0B4K6L3 R-DME-9013023 https://reactome.org/PathwayBrowser/#/R-DME-9013023 RHOB GEFs activate RHOB IEA Drosophila melanogaster A0A0B4K6M2 R-DME-210426 https://reactome.org/PathwayBrowser/#/R-DME-210426 Glutamate synaptic vesicle docking and priming IEA Drosophila melanogaster A0A0B4K6M2 R-DME-210430 https://reactome.org/PathwayBrowser/#/R-DME-210430 Release of L-Glutamate at the synapse IEA Drosophila melanogaster A0A0B4K6M2 R-DME-372505 https://reactome.org/PathwayBrowser/#/R-DME-372505 Acetylcholine synaptic vesicle docking and priming IEA Drosophila melanogaster A0A0B4K6M2 R-DME-372529 https://reactome.org/PathwayBrowser/#/R-DME-372529 Release of acetylcholine at the synapse IEA Drosophila melanogaster A0A0B4K6M2 R-DME-374899 https://reactome.org/PathwayBrowser/#/R-DME-374899 Release of noradrenaline at the synapse IEA Drosophila melanogaster A0A0B4K6M2 R-DME-374922 https://reactome.org/PathwayBrowser/#/R-DME-374922 Noradrenalin synaptic vesicle docking and priming IEA Drosophila melanogaster A0A0B4K6M2 R-DME-380574 https://reactome.org/PathwayBrowser/#/R-DME-380574 Dopamine synaptic vesicle docking and priming IEA Drosophila melanogaster A0A0B4K6M2 R-DME-380869 https://reactome.org/PathwayBrowser/#/R-DME-380869 Release of docked dopamine loaded synaptic vesicle IEA Drosophila melanogaster A0A0B4K6M2 R-DME-380901 https://reactome.org/PathwayBrowser/#/R-DME-380901 Release of docked serotonin loaded synaptic vesicle IEA Drosophila melanogaster A0A0B4K6M2 R-DME-380905 https://reactome.org/PathwayBrowser/#/R-DME-380905 Serotonin loaded synaptic vesicle docking and priming IEA Drosophila melanogaster A0A0B4K6M2 R-DME-888589 https://reactome.org/PathwayBrowser/#/R-DME-888589 Release of GABA at the synapse IEA Drosophila melanogaster A0A0B4K6M2 R-DME-917744 https://reactome.org/PathwayBrowser/#/R-DME-917744 GABA loaded synaptic vesicle Docking and Priming IEA Drosophila melanogaster A0A0B4K6N2 R-DME-8877192 https://reactome.org/PathwayBrowser/#/R-DME-8877192 RUNX1 binds FOXP3 IEA Drosophila melanogaster A0A0B4K6N4 R-DME-445699 https://reactome.org/PathwayBrowser/#/R-DME-445699 ATP Hydrolysis By Myosin IEA Drosophila melanogaster A0A0B4K6N4 R-DME-445700 https://reactome.org/PathwayBrowser/#/R-DME-445700 Myosin Binds ATP IEA Drosophila melanogaster A0A0B4K6N4 R-DME-445704 https://reactome.org/PathwayBrowser/#/R-DME-445704 Calcium Binds Caldesmon IEA Drosophila melanogaster A0A0B4K6N4 R-DME-445705 https://reactome.org/PathwayBrowser/#/R-DME-445705 Release Of ADP From Myosin IEA Drosophila melanogaster A0A0B4K6N4 R-DME-9018787 https://reactome.org/PathwayBrowser/#/R-DME-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Drosophila melanogaster A0A0B4K6Q5 R-DME-162857 https://reactome.org/PathwayBrowser/#/R-DME-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Drosophila melanogaster A0A0B4K6W9 R-DME-72103 https://reactome.org/PathwayBrowser/#/R-DME-72103 Formation of pre-mRNPs IEA Drosophila melanogaster A0A0B4K6W9 R-DME-9770141 https://reactome.org/PathwayBrowser/#/R-DME-9770141 Formation of the Spliceosomal C* complex IEA Drosophila melanogaster A0A0B4K6W9 R-DME-9770236 https://reactome.org/PathwayBrowser/#/R-DME-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Drosophila melanogaster A0A0B4K6W9 R-DME-9794542 https://reactome.org/PathwayBrowser/#/R-DME-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Drosophila melanogaster A0A0B4K6Y7 R-DME-351871 https://reactome.org/PathwayBrowser/#/R-DME-351871 Caspase-mediated cleavage of Z0-2 IEA Drosophila melanogaster A0A0B4K6Y7 R-DME-351913 https://reactome.org/PathwayBrowser/#/R-DME-351913 Caspase-mediated cleavage of TJP1 IEA Drosophila melanogaster A0A0B4K6Y7 R-DME-9013009 https://reactome.org/PathwayBrowser/#/R-DME-9013009 RHOA binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4K6Y7 R-DME-9013024 https://reactome.org/PathwayBrowser/#/R-DME-9013024 RHOB binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4K6Z6 R-DME-376122 https://reactome.org/PathwayBrowser/#/R-DME-376122 DSCAM/DSCAML1 homodimerization IEA Drosophila melanogaster A0A0B4K765 R-DME-400143 https://reactome.org/PathwayBrowser/#/R-DME-400143 Fatty acid ligands activate PPARA IEA Drosophila melanogaster A0A0B4K765 R-DME-400183 https://reactome.org/PathwayBrowser/#/R-DME-400183 PPARA:RXRA binds Corepressors of PPARA IEA Drosophila melanogaster A0A0B4K765 R-DME-8936584 https://reactome.org/PathwayBrowser/#/R-DME-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Drosophila melanogaster A0A0B4K765 R-DME-8936608 https://reactome.org/PathwayBrowser/#/R-DME-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Drosophila melanogaster A0A0B4K765 R-DME-8937022 https://reactome.org/PathwayBrowser/#/R-DME-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Drosophila melanogaster A0A0B4K765 R-DME-8937113 https://reactome.org/PathwayBrowser/#/R-DME-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Drosophila melanogaster A0A0B4K765 R-DME-9734475 https://reactome.org/PathwayBrowser/#/R-DME-9734475 PPARA binds fibrates IEA Drosophila melanogaster A0A0B4K765 R-DME-9825754 https://reactome.org/PathwayBrowser/#/R-DME-9825754 HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter IEA Drosophila melanogaster A0A0B4K765 R-DME-9858647 https://reactome.org/PathwayBrowser/#/R-DME-9858647 HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter IEA Drosophila melanogaster A0A0B4K774 R-DME-2029465 https://reactome.org/PathwayBrowser/#/R-DME-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Drosophila melanogaster A0A0B4K774 R-DME-2029466 https://reactome.org/PathwayBrowser/#/R-DME-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Drosophila melanogaster A0A0B4K774 R-DME-2029469 https://reactome.org/PathwayBrowser/#/R-DME-2029469 p-ERK phosphorylates WAVEs and ABI IEA Drosophila melanogaster A0A0B4K774 R-DME-2130194 https://reactome.org/PathwayBrowser/#/R-DME-2130194 ABL phosphorylates WAVEs IEA Drosophila melanogaster A0A0B4K774 R-DME-2197690 https://reactome.org/PathwayBrowser/#/R-DME-2197690 Detachment of WASP/WAVE IEA Drosophila melanogaster A0A0B4K774 R-DME-9013145 https://reactome.org/PathwayBrowser/#/R-DME-9013145 RAC1 binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4K774 R-DME-9014294 https://reactome.org/PathwayBrowser/#/R-DME-9014294 RAC2 binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4K774 R-DME-9018808 https://reactome.org/PathwayBrowser/#/R-DME-9018808 RAC3 binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4K7I2 R-DME-72103 https://reactome.org/PathwayBrowser/#/R-DME-72103 Formation of pre-mRNPs IEA Drosophila melanogaster A0A0B4K7I2 R-DME-9770141 https://reactome.org/PathwayBrowser/#/R-DME-9770141 Formation of the Spliceosomal C* complex IEA Drosophila melanogaster A0A0B4K7I2 R-DME-9770236 https://reactome.org/PathwayBrowser/#/R-DME-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Drosophila melanogaster A0A0B4K7I2 R-DME-9794542 https://reactome.org/PathwayBrowser/#/R-DME-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Drosophila melanogaster A0A0B4K7J2 R-DME-111439 https://reactome.org/PathwayBrowser/#/R-DME-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Drosophila melanogaster A0A0B4K7J2 R-DME-158441 https://reactome.org/PathwayBrowser/#/R-DME-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Drosophila melanogaster A0A0B4K7J2 R-DME-158447 https://reactome.org/PathwayBrowser/#/R-DME-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Drosophila melanogaster A0A0B4K7J2 R-DME-158481 https://reactome.org/PathwayBrowser/#/R-DME-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Drosophila melanogaster A0A0B4K7J2 R-DME-158484 https://reactome.org/PathwayBrowser/#/R-DME-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Drosophila melanogaster A0A0B4K7J2 R-DME-159046 https://reactome.org/PathwayBrowser/#/R-DME-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Drosophila melanogaster A0A0B4K7J2 R-DME-159050 https://reactome.org/PathwayBrowser/#/R-DME-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Drosophila melanogaster A0A0B4K7J2 R-DME-170825 https://reactome.org/PathwayBrowser/#/R-DME-170825 NPC exports GCK1 from nucleus IEA Drosophila melanogaster A0A0B4K7J2 R-DME-2990882 https://reactome.org/PathwayBrowser/#/R-DME-2990882 CDK1 phosphorylates NUP98 IEA Drosophila melanogaster A0A0B4K7J2 R-DME-3000411 https://reactome.org/PathwayBrowser/#/R-DME-3000411 RANBP2 SUMOylates PML with SUMO2 IEA Drosophila melanogaster A0A0B4K7J2 R-DME-4551679 https://reactome.org/PathwayBrowser/#/R-DME-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Drosophila melanogaster A0A0B4K7J2 R-DME-4615987 https://reactome.org/PathwayBrowser/#/R-DME-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Drosophila melanogaster A0A0B4K7J2 R-DME-4655355 https://reactome.org/PathwayBrowser/#/R-DME-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Drosophila melanogaster A0A0B4K7J2 R-DME-5578744 https://reactome.org/PathwayBrowser/#/R-DME-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Drosophila melanogaster A0A0B4K7J2 R-DME-75097 https://reactome.org/PathwayBrowser/#/R-DME-75097 Transport of the export-competent mRNP complex through the NPC IEA Drosophila melanogaster A0A0B4K7J2 R-DME-75098 https://reactome.org/PathwayBrowser/#/R-DME-75098 mRNP complex dissociates from cytosolic face of NPC IEA Drosophila melanogaster A0A0B4K7J2 R-DME-77587 https://reactome.org/PathwayBrowser/#/R-DME-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Drosophila melanogaster A0A0B4K7J2 R-DME-77594 https://reactome.org/PathwayBrowser/#/R-DME-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Drosophila melanogaster A0A0B4K7J3 R-DME-8858369 https://reactome.org/PathwayBrowser/#/R-DME-8858369 ACVRL1 binds BMP9,BMP10 IEA Drosophila melanogaster A0A0B4K7J4 R-DME-8853745 https://reactome.org/PathwayBrowser/#/R-DME-8853745 RET binds GFRA1,GFRA3 IEA Drosophila melanogaster A0A0B4K7J4 R-DME-8871226 https://reactome.org/PathwayBrowser/#/R-DME-8871226 RET binds GFRA1,GFRA2 IEA Drosophila melanogaster A0A0B4K7J4 R-DME-8871227 https://reactome.org/PathwayBrowser/#/R-DME-8871227 RET binds GFRA4 IEA Drosophila melanogaster A0A0B4K7Q6 R-DME-1011598 https://reactome.org/PathwayBrowser/#/R-DME-1011598 DOCKs bind to RhoGEFs IEA Drosophila melanogaster A0A0B4K7Q6 R-DME-418850 https://reactome.org/PathwayBrowser/#/R-DME-418850 Activation of Cdc42 IEA Drosophila melanogaster A0A0B4K7Q6 R-DME-418856 https://reactome.org/PathwayBrowser/#/R-DME-418856 Activation of Rac1 IEA Drosophila melanogaster A0A0B4K7Q6 R-DME-418858 https://reactome.org/PathwayBrowser/#/R-DME-418858 RhoGTPase GEF's recruited to DCC IEA Drosophila melanogaster A0A0B4K7Q6 R-DME-5218811 https://reactome.org/PathwayBrowser/#/R-DME-5218811 DOCK180:ELMO binds CRK IEA Drosophila melanogaster A0A0B4K7Q6 R-DME-5218839 https://reactome.org/PathwayBrowser/#/R-DME-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Drosophila melanogaster A0A0B4K7Q6 R-DME-6798749 https://reactome.org/PathwayBrowser/#/R-DME-6798749 Exocytosis of specific granule lumen proteins IEA Drosophila melanogaster A0A0B4K7Q6 R-DME-8848611 https://reactome.org/PathwayBrowser/#/R-DME-8848611 Phosphorylated PXN recruits the CRK complex IEA Drosophila melanogaster A0A0B4K7Q6 R-DME-8848618 https://reactome.org/PathwayBrowser/#/R-DME-8848618 Activation of RAC1 by the PXN:CRK complex IEA Drosophila melanogaster A0A0B4K7Q6 R-DME-8980691 https://reactome.org/PathwayBrowser/#/R-DME-8980691 RHOA GEFs activate RHOA IEA Drosophila melanogaster A0A0B4K7Q6 R-DME-9013143 https://reactome.org/PathwayBrowser/#/R-DME-9013143 RAC1 GEFs activate RAC1 IEA Drosophila melanogaster A0A0B4K7Q6 R-DME-9014296 https://reactome.org/PathwayBrowser/#/R-DME-9014296 RAC2 GEFs activate RAC2 IEA Drosophila melanogaster A0A0B4K7Q6 R-DME-9014449 https://reactome.org/PathwayBrowser/#/R-DME-9014449 RHOG binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4K7S6 R-DME-111437 https://reactome.org/PathwayBrowser/#/R-DME-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Drosophila melanogaster A0A0B4K7S6 R-DME-111438 https://reactome.org/PathwayBrowser/#/R-DME-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Drosophila melanogaster A0A0B4K7S6 R-DME-77585 https://reactome.org/PathwayBrowser/#/R-DME-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Drosophila melanogaster A0A0B4K7S6 R-DME-77586 https://reactome.org/PathwayBrowser/#/R-DME-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Drosophila melanogaster A0A0B4K7S6 R-DME-975040 https://reactome.org/PathwayBrowser/#/R-DME-975040 KRAB-ZNF / KAP Interaction IEA Drosophila melanogaster A0A0B4K7S6 R-DME-9842833 https://reactome.org/PathwayBrowser/#/R-DME-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Drosophila melanogaster A0A0B4K7S6 R-DME-9842835 https://reactome.org/PathwayBrowser/#/R-DME-9842835 KRAB-ZFP binds retroelement DNA in chromatin IEA Drosophila melanogaster A0A0B4K7S6 R-DME-9842839 https://reactome.org/PathwayBrowser/#/R-DME-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Drosophila melanogaster A0A0B4K7S6 R-DME-9843978 https://reactome.org/PathwayBrowser/#/R-DME-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Drosophila melanogaster A0A0B4K7V4 R-DME-351963 https://reactome.org/PathwayBrowser/#/R-DME-351963 SLC6A18 transports Gly from extracellular region to cytosol IEA Drosophila melanogaster A0A0B4K7V4 R-DME-352052 https://reactome.org/PathwayBrowser/#/R-DME-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Drosophila melanogaster A0A0B4K7V4 R-DME-352059 https://reactome.org/PathwayBrowser/#/R-DME-352059 SLC6A15-mediated amino acid uptake IEA Drosophila melanogaster A0A0B4K7V4 R-DME-375473 https://reactome.org/PathwayBrowser/#/R-DME-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol IEA Drosophila melanogaster A0A0B4K7Y4 R-DME-1482961 https://reactome.org/PathwayBrowser/#/R-DME-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Drosophila melanogaster A0A0B4K7Y4 R-DME-1482962 https://reactome.org/PathwayBrowser/#/R-DME-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Drosophila melanogaster A0A0B4K7Y4 R-DME-1482973 https://reactome.org/PathwayBrowser/#/R-DME-1482973 CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane IEA Drosophila melanogaster A0A0B4K838 R-DME-1013012 https://reactome.org/PathwayBrowser/#/R-DME-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Drosophila melanogaster A0A0B4K838 R-DME-1013013 https://reactome.org/PathwayBrowser/#/R-DME-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Drosophila melanogaster A0A0B4K838 R-DME-1013020 https://reactome.org/PathwayBrowser/#/R-DME-1013020 Activation of GIRK/Kir3 Channels IEA Drosophila melanogaster A0A0B4K838 R-DME-167419 https://reactome.org/PathwayBrowser/#/R-DME-167419 The receptor:G-protein complex releases GDP IEA Drosophila melanogaster A0A0B4K838 R-DME-167429 https://reactome.org/PathwayBrowser/#/R-DME-167429 The receptor:G-protein complex binds GTP IEA Drosophila melanogaster A0A0B4K838 R-DME-167433 https://reactome.org/PathwayBrowser/#/R-DME-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Drosophila melanogaster A0A0B4K838 R-DME-2530501 https://reactome.org/PathwayBrowser/#/R-DME-2530501 FNTA:FNTB transfers FARN to GNGT1 IEA Drosophila melanogaster A0A0B4K838 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster A0A0B4K838 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster A0A0B4K838 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster A0A0B4K838 R-DME-392195 https://reactome.org/PathwayBrowser/#/R-DME-392195 Gi activation by P2Y purinoceptor 12 IEA Drosophila melanogaster A0A0B4K838 R-DME-392300 https://reactome.org/PathwayBrowser/#/R-DME-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Drosophila melanogaster A0A0B4K838 R-DME-392870 https://reactome.org/PathwayBrowser/#/R-DME-392870 Gs activation by prostacyclin receptor IEA Drosophila melanogaster A0A0B4K838 R-DME-3965444 https://reactome.org/PathwayBrowser/#/R-DME-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Drosophila melanogaster A0A0B4K838 R-DME-3965447 https://reactome.org/PathwayBrowser/#/R-DME-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Drosophila melanogaster A0A0B4K838 R-DME-398040 https://reactome.org/PathwayBrowser/#/R-DME-398040 Gbeta:gamma activation of PLC beta IEA Drosophila melanogaster A0A0B4K838 R-DME-398193 https://reactome.org/PathwayBrowser/#/R-DME-398193 PLC beta-mediated PIP2 hydrolysis IEA Drosophila melanogaster A0A0B4K838 R-DME-400037 https://reactome.org/PathwayBrowser/#/R-DME-400037 Gi,Go Heterotrimeric G-protein complex dissociates IEA Drosophila melanogaster A0A0B4K838 R-DME-400092 https://reactome.org/PathwayBrowser/#/R-DME-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Drosophila melanogaster A0A0B4K838 R-DME-400097 https://reactome.org/PathwayBrowser/#/R-DME-400097 G-beta:G-gamma inhibits Adenylate cyclase IEA Drosophila melanogaster A0A0B4K838 R-DME-428749 https://reactome.org/PathwayBrowser/#/R-DME-428749 Activated TP receptor binds G-proten Gq IEA Drosophila melanogaster A0A0B4K838 R-DME-428750 https://reactome.org/PathwayBrowser/#/R-DME-428750 Gq activation by TP receptor IEA Drosophila melanogaster A0A0B4K838 R-DME-428752 https://reactome.org/PathwayBrowser/#/R-DME-428752 Dissociation of the TP:Gq complex IEA Drosophila melanogaster A0A0B4K838 R-DME-428909 https://reactome.org/PathwayBrowser/#/R-DME-428909 Activated TP receptor binds G-protein G13 IEA Drosophila melanogaster A0A0B4K838 R-DME-428917 https://reactome.org/PathwayBrowser/#/R-DME-428917 G13 activation by TP receptor IEA Drosophila melanogaster A0A0B4K838 R-DME-428918 https://reactome.org/PathwayBrowser/#/R-DME-428918 Dissociation of the TP:G13 complex IEA Drosophila melanogaster A0A0B4K838 R-DME-500717 https://reactome.org/PathwayBrowser/#/R-DME-500717 Activation of GRIK3 homomer IEA Drosophila melanogaster A0A0B4K838 R-DME-6814418 https://reactome.org/PathwayBrowser/#/R-DME-6814418 PDCL promotes formation of G-beta:G-gamma heterodimers IEA Drosophila melanogaster A0A0B4K838 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster A0A0B4K838 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster A0A0B4K838 R-DME-749453 https://reactome.org/PathwayBrowser/#/R-DME-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Drosophila melanogaster A0A0B4K838 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster A0A0B4K838 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster A0A0B4K838 R-DME-750993 https://reactome.org/PathwayBrowser/#/R-DME-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Drosophila melanogaster A0A0B4K838 R-DME-751001 https://reactome.org/PathwayBrowser/#/R-DME-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Drosophila melanogaster A0A0B4K838 R-DME-751019 https://reactome.org/PathwayBrowser/#/R-DME-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Drosophila melanogaster A0A0B4K838 R-DME-751027 https://reactome.org/PathwayBrowser/#/R-DME-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Drosophila melanogaster A0A0B4K838 R-DME-751029 https://reactome.org/PathwayBrowser/#/R-DME-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Drosophila melanogaster A0A0B4K838 R-DME-751039 https://reactome.org/PathwayBrowser/#/R-DME-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Drosophila melanogaster A0A0B4K838 R-DME-8850560 https://reactome.org/PathwayBrowser/#/R-DME-8850560 G-protein alpha releases G-protein heterotrimer from PDCL IEA Drosophila melanogaster A0A0B4K838 R-DME-8964241 https://reactome.org/PathwayBrowser/#/R-DME-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Drosophila melanogaster A0A0B4K838 R-DME-8964271 https://reactome.org/PathwayBrowser/#/R-DME-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Drosophila melanogaster A0A0B4K838 R-DME-8964317 https://reactome.org/PathwayBrowser/#/R-DME-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Drosophila melanogaster A0A0B4K838 R-DME-8964599 https://reactome.org/PathwayBrowser/#/R-DME-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Drosophila melanogaster A0A0B4K838 R-DME-8964604 https://reactome.org/PathwayBrowser/#/R-DME-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Drosophila melanogaster A0A0B4K838 R-DME-8964605 https://reactome.org/PathwayBrowser/#/R-DME-8964605 PAK1:ARHGEF6 complex binds G-protein beta-gamma complex IEA Drosophila melanogaster A0A0B4K838 R-DME-8964614 https://reactome.org/PathwayBrowser/#/R-DME-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Drosophila melanogaster A0A0B4K838 R-DME-8964634 https://reactome.org/PathwayBrowser/#/R-DME-8964634 CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex IEA Drosophila melanogaster A0A0B4K838 R-DME-9021596 https://reactome.org/PathwayBrowser/#/R-DME-9021596 Membrane estrogen receptors bind SRC IEA Drosophila melanogaster A0A0B4K838 R-DME-9021600 https://reactome.org/PathwayBrowser/#/R-DME-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Drosophila melanogaster A0A0B4K838 R-DME-9021601 https://reactome.org/PathwayBrowser/#/R-DME-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Drosophila melanogaster A0A0B4K859 R-DME-111439 https://reactome.org/PathwayBrowser/#/R-DME-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Drosophila melanogaster A0A0B4K859 R-DME-158441 https://reactome.org/PathwayBrowser/#/R-DME-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Drosophila melanogaster A0A0B4K859 R-DME-158447 https://reactome.org/PathwayBrowser/#/R-DME-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Drosophila melanogaster A0A0B4K859 R-DME-158481 https://reactome.org/PathwayBrowser/#/R-DME-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Drosophila melanogaster A0A0B4K859 R-DME-158484 https://reactome.org/PathwayBrowser/#/R-DME-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Drosophila melanogaster A0A0B4K859 R-DME-159046 https://reactome.org/PathwayBrowser/#/R-DME-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Drosophila melanogaster A0A0B4K859 R-DME-159050 https://reactome.org/PathwayBrowser/#/R-DME-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Drosophila melanogaster A0A0B4K859 R-DME-170825 https://reactome.org/PathwayBrowser/#/R-DME-170825 NPC exports GCK1 from nucleus IEA Drosophila melanogaster A0A0B4K859 R-DME-2990882 https://reactome.org/PathwayBrowser/#/R-DME-2990882 CDK1 phosphorylates NUP98 IEA Drosophila melanogaster A0A0B4K859 R-DME-3000411 https://reactome.org/PathwayBrowser/#/R-DME-3000411 RANBP2 SUMOylates PML with SUMO2 IEA Drosophila melanogaster A0A0B4K859 R-DME-4551679 https://reactome.org/PathwayBrowser/#/R-DME-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Drosophila melanogaster A0A0B4K859 R-DME-4615987 https://reactome.org/PathwayBrowser/#/R-DME-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Drosophila melanogaster A0A0B4K859 R-DME-4655355 https://reactome.org/PathwayBrowser/#/R-DME-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Drosophila melanogaster A0A0B4K859 R-DME-5578744 https://reactome.org/PathwayBrowser/#/R-DME-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Drosophila melanogaster A0A0B4K859 R-DME-75097 https://reactome.org/PathwayBrowser/#/R-DME-75097 Transport of the export-competent mRNP complex through the NPC IEA Drosophila melanogaster A0A0B4K859 R-DME-75098 https://reactome.org/PathwayBrowser/#/R-DME-75098 mRNP complex dissociates from cytosolic face of NPC IEA Drosophila melanogaster A0A0B4K859 R-DME-77587 https://reactome.org/PathwayBrowser/#/R-DME-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Drosophila melanogaster A0A0B4K859 R-DME-77594 https://reactome.org/PathwayBrowser/#/R-DME-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Drosophila melanogaster A0A0B4K859 R-DME-9634169 https://reactome.org/PathwayBrowser/#/R-DME-9634169 POM121 and NDC1 bind the Nup93 complex IEA Drosophila melanogaster A0A0B4K866 R-DME-210420 https://reactome.org/PathwayBrowser/#/R-DME-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Drosophila melanogaster A0A0B4K866 R-DME-265645 https://reactome.org/PathwayBrowser/#/R-DME-265645 Calcium Influx through Voltage-gated Calcium Channels IEA Drosophila melanogaster A0A0B4K866 R-DME-5577213 https://reactome.org/PathwayBrowser/#/R-DME-5577213 LTCC multimer transports Ca2+ from extracellular region to cytosol IEA Drosophila melanogaster A0A0B4K866 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster A0A0B4K897 R-DME-421831 https://reactome.org/PathwayBrowser/#/R-DME-421831 trans-Golgi Network Coat Assembly IEA Drosophila melanogaster A0A0B4K897 R-DME-421833 https://reactome.org/PathwayBrowser/#/R-DME-421833 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture IEA Drosophila melanogaster A0A0B4K897 R-DME-421835 https://reactome.org/PathwayBrowser/#/R-DME-421835 trans-Golgi Network Vesicle Scission IEA Drosophila melanogaster A0A0B4K8B1 R-DME-6792445 https://reactome.org/PathwayBrowser/#/R-DME-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Drosophila melanogaster A0A0B4KEE7 R-DME-994148 https://reactome.org/PathwayBrowser/#/R-DME-994148 LRRC16A binds F-actin capping protein IEA Drosophila melanogaster A0A0B4KEG0 R-DME-8955030 https://reactome.org/PathwayBrowser/#/R-DME-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Drosophila melanogaster A0A0B4KEG0 R-DME-9838081 https://reactome.org/PathwayBrowser/#/R-DME-9838081 LONP1 degrades mitochondrial matrix proteins IEA Drosophila melanogaster A0A0B4KEG0 R-DME-9838093 https://reactome.org/PathwayBrowser/#/R-DME-9838093 LONP1 binds mitochondrial matrix proteins IEA Drosophila melanogaster A0A0B4KEI1 R-DME-163214 https://reactome.org/PathwayBrowser/#/R-DME-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Drosophila melanogaster A0A0B4KEI1 R-DME-9865663 https://reactome.org/PathwayBrowser/#/R-DME-9865663 MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex IEA Drosophila melanogaster A0A0B4KEN4 R-DME-9013009 https://reactome.org/PathwayBrowser/#/R-DME-9013009 RHOA binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KEN4 R-DME-9013024 https://reactome.org/PathwayBrowser/#/R-DME-9013024 RHOB binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KEN4 R-DME-9013145 https://reactome.org/PathwayBrowser/#/R-DME-9013145 RAC1 binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KEN4 R-DME-9014294 https://reactome.org/PathwayBrowser/#/R-DME-9014294 RAC2 binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KEN4 R-DME-9014449 https://reactome.org/PathwayBrowser/#/R-DME-9014449 RHOG binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KEN4 R-DME-9018746 https://reactome.org/PathwayBrowser/#/R-DME-9018746 RHOQ binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KEN4 R-DME-9018758 https://reactome.org/PathwayBrowser/#/R-DME-9018758 RHOH binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KEN4 R-DME-9018766 https://reactome.org/PathwayBrowser/#/R-DME-9018766 RHOU binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KEN4 R-DME-9018794 https://reactome.org/PathwayBrowser/#/R-DME-9018794 RHOV binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KEN4 R-DME-9018808 https://reactome.org/PathwayBrowser/#/R-DME-9018808 RAC3 binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KEN4 R-DME-9693125 https://reactome.org/PathwayBrowser/#/R-DME-9693125 RHOF binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KEN4 R-DME-9693198 https://reactome.org/PathwayBrowser/#/R-DME-9693198 RHOD binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KEU3 R-DME-5658424 https://reactome.org/PathwayBrowser/#/R-DME-5658424 KBTBD7:CUL3:RBX1 ubiquitinates NF1 IEA Drosophila melanogaster A0A0B4KEU3 R-DME-8952630 https://reactome.org/PathwayBrowser/#/R-DME-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex IEA Drosophila melanogaster A0A0B4KEU3 R-DME-8952631 https://reactome.org/PathwayBrowser/#/R-DME-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Drosophila melanogaster A0A0B4KEU3 R-DME-8955241 https://reactome.org/PathwayBrowser/#/R-DME-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Drosophila melanogaster A0A0B4KEU3 R-DME-8956040 https://reactome.org/PathwayBrowser/#/R-DME-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Drosophila melanogaster A0A0B4KEU3 R-DME-983140 https://reactome.org/PathwayBrowser/#/R-DME-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Drosophila melanogaster A0A0B4KEU3 R-DME-983147 https://reactome.org/PathwayBrowser/#/R-DME-983147 Release of E3 from polyubiquitinated substrate IEA Drosophila melanogaster A0A0B4KEU3 R-DME-983156 https://reactome.org/PathwayBrowser/#/R-DME-983156 Polyubiquitination of substrate IEA Drosophila melanogaster A0A0B4KEU3 R-DME-983157 https://reactome.org/PathwayBrowser/#/R-DME-983157 Interaction of E3 with substrate and E2-Ub complex IEA Drosophila melanogaster A0A0B4KEY8 R-DME-983140 https://reactome.org/PathwayBrowser/#/R-DME-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Drosophila melanogaster A0A0B4KEY8 R-DME-983147 https://reactome.org/PathwayBrowser/#/R-DME-983147 Release of E3 from polyubiquitinated substrate IEA Drosophila melanogaster A0A0B4KEY8 R-DME-983156 https://reactome.org/PathwayBrowser/#/R-DME-983156 Polyubiquitination of substrate IEA Drosophila melanogaster A0A0B4KEY8 R-DME-983157 https://reactome.org/PathwayBrowser/#/R-DME-983157 Interaction of E3 with substrate and E2-Ub complex IEA Drosophila melanogaster A0A0B4KEZ3 R-DME-1236940 https://reactome.org/PathwayBrowser/#/R-DME-1236940 Exogenous soluble antigen targeted to more stable early endosome IEA Drosophila melanogaster A0A0B4KEZ3 R-DME-1236941 https://reactome.org/PathwayBrowser/#/R-DME-1236941 Internalization of receptor bound antigen into clathrin coted vesicles IEA Drosophila melanogaster A0A0B4KEZ3 R-DME-1236955 https://reactome.org/PathwayBrowser/#/R-DME-1236955 Movement of clathrin coated vesicles into early endosome IEA Drosophila melanogaster A0A0B4KEZ3 R-DME-6798743 https://reactome.org/PathwayBrowser/#/R-DME-6798743 Exocytosis of secretory granule membrane proteins IEA Drosophila melanogaster A0A0B4KEZ3 R-DME-6798747 https://reactome.org/PathwayBrowser/#/R-DME-6798747 Exocytosis of tertiary granule membrane proteins IEA Drosophila melanogaster A0A0B4KEZ3 R-DME-6799350 https://reactome.org/PathwayBrowser/#/R-DME-6799350 Exocytosis of specific granule membrane proteins IEA Drosophila melanogaster A0A0B4KEZ3 R-DME-6800426 https://reactome.org/PathwayBrowser/#/R-DME-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Drosophila melanogaster A0A0B4KEZ3 R-DME-8855711 https://reactome.org/PathwayBrowser/#/R-DME-8855711 PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins IEA Drosophila melanogaster A0A0B4KEZ3 R-DME-8858500 https://reactome.org/PathwayBrowser/#/R-DME-8858500 CLEC10A binds Tn-MUC1 IEA Drosophila melanogaster A0A0B4KF12 R-DME-9702818 https://reactome.org/PathwayBrowser/#/R-DME-9702818 CALCR binds erenumab IEA Drosophila melanogaster A0A0B4KF12 R-DME-9702849 https://reactome.org/PathwayBrowser/#/R-DME-9702849 CALCR binds gepants IEA Drosophila melanogaster A0A0B4KF19 R-DME-174164 https://reactome.org/PathwayBrowser/#/R-DME-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Drosophila melanogaster A0A0B4KF19 R-DME-69195 https://reactome.org/PathwayBrowser/#/R-DME-69195 Phosphorylation of Cyclin E:CDK2 complexes by WEE1 IEA Drosophila melanogaster A0A0B4KF25 R-DME-3321805 https://reactome.org/PathwayBrowser/#/R-DME-3321805 NSL acetylates histone H4 IEA Drosophila melanogaster A0A0B4KF25 R-DME-9828175 https://reactome.org/PathwayBrowser/#/R-DME-9828175 Formation of the NSL complex IEA Drosophila melanogaster A0A0B4KF28 R-DME-8952618 https://reactome.org/PathwayBrowser/#/R-DME-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Drosophila melanogaster A0A0B4KF28 R-DME-8952620 https://reactome.org/PathwayBrowser/#/R-DME-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Drosophila melanogaster A0A0B4KF28 R-DME-8955241 https://reactome.org/PathwayBrowser/#/R-DME-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Drosophila melanogaster A0A0B4KF28 R-DME-8956040 https://reactome.org/PathwayBrowser/#/R-DME-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Drosophila melanogaster A0A0B4KF28 R-DME-8956200 https://reactome.org/PathwayBrowser/#/R-DME-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Drosophila melanogaster A0A0B4KF28 R-DME-983140 https://reactome.org/PathwayBrowser/#/R-DME-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Drosophila melanogaster A0A0B4KF28 R-DME-983147 https://reactome.org/PathwayBrowser/#/R-DME-983147 Release of E3 from polyubiquitinated substrate IEA Drosophila melanogaster A0A0B4KF28 R-DME-983156 https://reactome.org/PathwayBrowser/#/R-DME-983156 Polyubiquitination of substrate IEA Drosophila melanogaster A0A0B4KF28 R-DME-983157 https://reactome.org/PathwayBrowser/#/R-DME-983157 Interaction of E3 with substrate and E2-Ub complex IEA Drosophila melanogaster A0A0B4KF40 R-DME-158468 https://reactome.org/PathwayBrowser/#/R-DME-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Drosophila melanogaster A0A0B4KF40 R-DME-158849 https://reactome.org/PathwayBrowser/#/R-DME-158849 Phenol can form a sulfate conjugate IEA Drosophila melanogaster A0A0B4KF40 R-DME-158860 https://reactome.org/PathwayBrowser/#/R-DME-158860 SULT1A1 dimer sulfonates NHABP IEA Drosophila melanogaster A0A0B4KF40 R-DME-159358 https://reactome.org/PathwayBrowser/#/R-DME-159358 SULT1A3,4 dimers sulfate DA to DAOS IEA Drosophila melanogaster A0A0B4KF40 R-DME-176474 https://reactome.org/PathwayBrowser/#/R-DME-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Drosophila melanogaster A0A0B4KF40 R-DME-176494 https://reactome.org/PathwayBrowser/#/R-DME-176494 SULTs transfer (SO4)2- group to 27HCHOL IEA Drosophila melanogaster A0A0B4KF40 R-DME-176517 https://reactome.org/PathwayBrowser/#/R-DME-176517 SULTs transfer (SO4)2- group to PREG IEA Drosophila melanogaster A0A0B4KF40 R-DME-176521 https://reactome.org/PathwayBrowser/#/R-DME-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Drosophila melanogaster A0A0B4KF40 R-DME-176585 https://reactome.org/PathwayBrowser/#/R-DME-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Drosophila melanogaster A0A0B4KF40 R-DME-176588 https://reactome.org/PathwayBrowser/#/R-DME-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Drosophila melanogaster A0A0B4KF40 R-DME-176604 https://reactome.org/PathwayBrowser/#/R-DME-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP IEA Drosophila melanogaster A0A0B4KF40 R-DME-176609 https://reactome.org/PathwayBrowser/#/R-DME-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Drosophila melanogaster A0A0B4KF40 R-DME-176631 https://reactome.org/PathwayBrowser/#/R-DME-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Drosophila melanogaster A0A0B4KF40 R-DME-176646 https://reactome.org/PathwayBrowser/#/R-DME-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP IEA Drosophila melanogaster A0A0B4KF40 R-DME-176664 https://reactome.org/PathwayBrowser/#/R-DME-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Drosophila melanogaster A0A0B4KF40 R-DME-176669 https://reactome.org/PathwayBrowser/#/R-DME-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP IEA Drosophila melanogaster A0A0B4KF40 R-DME-9753277 https://reactome.org/PathwayBrowser/#/R-DME-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Drosophila melanogaster A0A0B4KF65 R-DME-2046088 https://reactome.org/PathwayBrowser/#/R-DME-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Drosophila melanogaster A0A0B4KF65 R-DME-2046094 https://reactome.org/PathwayBrowser/#/R-DME-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Drosophila melanogaster A0A0B4KF65 R-DME-548800 https://reactome.org/PathwayBrowser/#/R-DME-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Drosophila melanogaster A0A0B4KF65 R-DME-548814 https://reactome.org/PathwayBrowser/#/R-DME-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Drosophila melanogaster A0A0B4KF65 R-DME-548815 https://reactome.org/PathwayBrowser/#/R-DME-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Drosophila melanogaster A0A0B4KF86 R-DME-5682385 https://reactome.org/PathwayBrowser/#/R-DME-5682385 The phagophore extends from the PIP3-enriched structure IEA Drosophila melanogaster A0A0B4KF86 R-DME-9840807 https://reactome.org/PathwayBrowser/#/R-DME-9840807 OPTN binds ATG9A IEA Drosophila melanogaster A0A0B4KFB3 R-DME-2464822 https://reactome.org/PathwayBrowser/#/R-DME-2464822 RDH12 reduces atRAL to atROL IEA Drosophila melanogaster A0A0B4KFE4 R-DME-201035 https://reactome.org/PathwayBrowser/#/R-DME-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Drosophila melanogaster A0A0B4KFE4 R-DME-434382 https://reactome.org/PathwayBrowser/#/R-DME-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell IEA Drosophila melanogaster A0A0B4KFE4 R-DME-548843 https://reactome.org/PathwayBrowser/#/R-DME-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Drosophila melanogaster A0A0B4KFK6 R-DME-165026 https://reactome.org/PathwayBrowser/#/R-DME-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Drosophila melanogaster A0A0B4KFK6 R-DME-2161500 https://reactome.org/PathwayBrowser/#/R-DME-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Drosophila melanogaster A0A0B4KFK6 R-DME-374896 https://reactome.org/PathwayBrowser/#/R-DME-374896 Uptake of Noradrenaline IEA Drosophila melanogaster A0A0B4KFK6 R-DME-374919 https://reactome.org/PathwayBrowser/#/R-DME-374919 Noradrenaline clearance from the synaptic cleft IEA Drosophila melanogaster A0A0B4KFK6 R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster A0A0B4KFK6 R-DME-549241 https://reactome.org/PathwayBrowser/#/R-DME-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Drosophila melanogaster A0A0B4KFK6 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster A0A0B4KFK6 R-DME-549297 https://reactome.org/PathwayBrowser/#/R-DME-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Drosophila melanogaster A0A0B4KFK6 R-DME-549304 https://reactome.org/PathwayBrowser/#/R-DME-549304 OCT3 mediates renal clearance of organic cations IEA Drosophila melanogaster A0A0B4KFK6 R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster A0A0B4KFK6 R-DME-561041 https://reactome.org/PathwayBrowser/#/R-DME-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Drosophila melanogaster A0A0B4KFK6 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster A0A0B4KFK6 R-DME-561059 https://reactome.org/PathwayBrowser/#/R-DME-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Drosophila melanogaster A0A0B4KFK6 R-DME-561072 https://reactome.org/PathwayBrowser/#/R-DME-561072 OCT3 mediates renal uptake of organic cations IEA Drosophila melanogaster A0A0B4KFK6 R-DME-561253 https://reactome.org/PathwayBrowser/#/R-DME-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Drosophila melanogaster A0A0B4KFK6 R-DME-5671707 https://reactome.org/PathwayBrowser/#/R-DME-5671707 Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA IEA Drosophila melanogaster A0A0B4KFK6 R-DME-9749583 https://reactome.org/PathwayBrowser/#/R-DME-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Drosophila melanogaster A0A0B4KFK6 R-DME-9794523 https://reactome.org/PathwayBrowser/#/R-DME-9794523 SLC22A1 transports Cipro into renal cell IEA Drosophila melanogaster A0A0B4KFK6 R-DME-9795207 https://reactome.org/PathwayBrowser/#/R-DME-9795207 SLC22A1 transports Cipro into hepatic cell IEA Drosophila melanogaster A0A0B4KFN3 R-DME-975040 https://reactome.org/PathwayBrowser/#/R-DME-975040 KRAB-ZNF / KAP Interaction IEA Drosophila melanogaster A0A0B4KFP2 R-DME-8954110 https://reactome.org/PathwayBrowser/#/R-DME-8954110 E2F6:TFDP1:EPC1 binds the PRC2 complex IEA Drosophila melanogaster A0A0B4KFP2 R-DME-8954117 https://reactome.org/PathwayBrowser/#/R-DME-8954117 E2F6:TFDP1 binds EPC1 IEA Drosophila melanogaster A0A0B4KFQ3 R-DME-211186 https://reactome.org/PathwayBrowser/#/R-DME-211186 Cleavage of DFF45 (224) by caspase-3 IEA Drosophila melanogaster A0A0B4KFQ3 R-DME-211190 https://reactome.org/PathwayBrowser/#/R-DME-211190 Caspase 3-mediated cleavage of DFF45 (117) IEA Drosophila melanogaster A0A0B4KFQ3 R-DME-211191 https://reactome.org/PathwayBrowser/#/R-DME-211191 Association of DFF with alpha:beta importin IEA Drosophila melanogaster A0A0B4KFQ3 R-DME-211206 https://reactome.org/PathwayBrowser/#/R-DME-211206 Translocation of DFF to the nucleus IEA Drosophila melanogaster A0A0B4KFQ3 R-DME-211207 https://reactome.org/PathwayBrowser/#/R-DME-211207 Cleaved fragments of DFF45 dissociate from DFF40 IEA Drosophila melanogaster A0A0B4KFQ3 R-DME-211224 https://reactome.org/PathwayBrowser/#/R-DME-211224 Association of DFF40 with DFF45 IEA Drosophila melanogaster A0A0B4KFQ3 R-DME-8856630 https://reactome.org/PathwayBrowser/#/R-DME-8856630 CIDEA:CIDEC binds lipid droplets IEA Drosophila melanogaster A0A0B4KFQ3 R-DME-9029667 https://reactome.org/PathwayBrowser/#/R-DME-9029667 DFF dissociates from importin-alpha:importin-beta IEA Drosophila melanogaster A0A0B4KFQ5 R-DME-6798747 https://reactome.org/PathwayBrowser/#/R-DME-6798747 Exocytosis of tertiary granule membrane proteins IEA Drosophila melanogaster A0A0B4KFQ5 R-DME-6799350 https://reactome.org/PathwayBrowser/#/R-DME-6799350 Exocytosis of specific granule membrane proteins IEA Drosophila melanogaster A0A0B4KFR5 R-DME-6811426 https://reactome.org/PathwayBrowser/#/R-DME-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Drosophila melanogaster A0A0B4KFR5 R-DME-983259 https://reactome.org/PathwayBrowser/#/R-DME-983259 Kinesins move along microtubules consuming ATP IEA Drosophila melanogaster A0A0B4KFT9 R-DME-8848993 https://reactome.org/PathwayBrowser/#/R-DME-8848993 Phosphorylated KHDRBS1 translocates to the cytosol IEA Drosophila melanogaster A0A0B4KFU6 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster A0A0B4KFU6 R-DME-390930 https://reactome.org/PathwayBrowser/#/R-DME-390930 5-HT2 receptor can bind serotonin IEA Drosophila melanogaster A0A0B4KFU6 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster A0A0B4KFU6 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster A0A0B4KFW5 R-DME-983140 https://reactome.org/PathwayBrowser/#/R-DME-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Drosophila melanogaster A0A0B4KFW5 R-DME-983147 https://reactome.org/PathwayBrowser/#/R-DME-983147 Release of E3 from polyubiquitinated substrate IEA Drosophila melanogaster A0A0B4KFW5 R-DME-983156 https://reactome.org/PathwayBrowser/#/R-DME-983156 Polyubiquitination of substrate IEA Drosophila melanogaster A0A0B4KFW5 R-DME-983157 https://reactome.org/PathwayBrowser/#/R-DME-983157 Interaction of E3 with substrate and E2-Ub complex IEA Drosophila melanogaster A0A0B4KFY0 R-DME-8854628 https://reactome.org/PathwayBrowser/#/R-DME-8854628 MYLIP dimer ubiquitinates VLDLR on Lys-839 IEA Drosophila melanogaster A0A0B4KFY0 R-DME-983140 https://reactome.org/PathwayBrowser/#/R-DME-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Drosophila melanogaster A0A0B4KFY0 R-DME-983147 https://reactome.org/PathwayBrowser/#/R-DME-983147 Release of E3 from polyubiquitinated substrate IEA Drosophila melanogaster A0A0B4KFY0 R-DME-983156 https://reactome.org/PathwayBrowser/#/R-DME-983156 Polyubiquitination of substrate IEA Drosophila melanogaster A0A0B4KFY0 R-DME-983157 https://reactome.org/PathwayBrowser/#/R-DME-983157 Interaction of E3 with substrate and E2-Ub complex IEA Drosophila melanogaster A0A0B4KFZ1 R-DME-1237042 https://reactome.org/PathwayBrowser/#/R-DME-1237042 AQP1 tetramer transports CO2 from extracellular region to cytosol IEA Drosophila melanogaster A0A0B4KFZ1 R-DME-1247649 https://reactome.org/PathwayBrowser/#/R-DME-1247649 AQP1 tetramer transports CO2 from cytosol to extracellular region IEA Drosophila melanogaster A0A0B4KFZ1 R-DME-432010 https://reactome.org/PathwayBrowser/#/R-DME-432010 Aquaporin-1 passively transports water into cell IEA Drosophila melanogaster A0A0B4KFZ1 R-DME-432054 https://reactome.org/PathwayBrowser/#/R-DME-432054 Aquaporin-1 passively transports water out of cell IEA Drosophila melanogaster A0A0B4KFZ1 R-DME-432065 https://reactome.org/PathwayBrowser/#/R-DME-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Drosophila melanogaster A0A0B4KFZ1 R-DME-432067 https://reactome.org/PathwayBrowser/#/R-DME-432067 Aquaporin-4 passively transports water out of cell IEA Drosophila melanogaster A0A0B4KFZ1 R-DME-432232 https://reactome.org/PathwayBrowser/#/R-DME-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Drosophila melanogaster A0A0B4KFZ1 R-DME-432237 https://reactome.org/PathwayBrowser/#/R-DME-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Drosophila melanogaster A0A0B4KFZ1 R-DME-507868 https://reactome.org/PathwayBrowser/#/R-DME-507868 Aquaporins passively transport water into cells IEA Drosophila melanogaster A0A0B4KFZ1 R-DME-507870 https://reactome.org/PathwayBrowser/#/R-DME-507870 Aquaporins passively transport water out of cells IEA Drosophila melanogaster A0A0B4KFZ4 R-DME-416985 https://reactome.org/PathwayBrowser/#/R-DME-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Drosophila melanogaster A0A0B4KG01 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster A0A0B4KG01 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster A0A0B4KG01 R-DME-391941 https://reactome.org/PathwayBrowser/#/R-DME-391941 BLT receptors can bind LTB4 IEA Drosophila melanogaster A0A0B4KG01 R-DME-391943 https://reactome.org/PathwayBrowser/#/R-DME-391943 CYSLT2 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster A0A0B4KG01 R-DME-6798747 https://reactome.org/PathwayBrowser/#/R-DME-6798747 Exocytosis of tertiary granule membrane proteins IEA Drosophila melanogaster A0A0B4KG01 R-DME-6799350 https://reactome.org/PathwayBrowser/#/R-DME-6799350 Exocytosis of specific granule membrane proteins IEA Drosophila melanogaster A0A0B4KG01 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster A0A0B4KG01 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster A0A0B4KG01 R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster A0A0B4KG01 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster A0A0B4KG11 R-DME-5654510 https://reactome.org/PathwayBrowser/#/R-DME-5654510 FGFRL1 binds SPRED1/2 IEA Drosophila melanogaster A0A0B4KG11 R-DME-5658231 https://reactome.org/PathwayBrowser/#/R-DME-5658231 RAS GAPs stimulate RAS GTPase activity IEA Drosophila melanogaster A0A0B4KG11 R-DME-5658424 https://reactome.org/PathwayBrowser/#/R-DME-5658424 KBTBD7:CUL3:RBX1 ubiquitinates NF1 IEA Drosophila melanogaster A0A0B4KG11 R-DME-5658430 https://reactome.org/PathwayBrowser/#/R-DME-5658430 NF1 is degraded by the proteasome IEA Drosophila melanogaster A0A0B4KG11 R-DME-5658435 https://reactome.org/PathwayBrowser/#/R-DME-5658435 RAS GAPs bind RAS:GTP IEA Drosophila melanogaster A0A0B4KG11 R-DME-5658438 https://reactome.org/PathwayBrowser/#/R-DME-5658438 SPRED dimer binds NF1 IEA Drosophila melanogaster A0A0B4KG35 R-DME-482772 https://reactome.org/PathwayBrowser/#/R-DME-482772 Release of platelet cytosolic components IEA Drosophila melanogaster A0A0B4KG38 R-DME-373746 https://reactome.org/PathwayBrowser/#/R-DME-373746 SEMA4D interacts with CD45 IEA Drosophila melanogaster A0A0B4KG38 R-DME-373750 https://reactome.org/PathwayBrowser/#/R-DME-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Drosophila melanogaster A0A0B4KG38 R-DME-399930 https://reactome.org/PathwayBrowser/#/R-DME-399930 Activation of PAK by Rac1 IEA Drosophila melanogaster A0A0B4KG38 R-DME-399933 https://reactome.org/PathwayBrowser/#/R-DME-399933 Sema3A binds Nrp-1 bound to PlexinA IEA Drosophila melanogaster A0A0B4KG38 R-DME-399939 https://reactome.org/PathwayBrowser/#/R-DME-399939 Autophosphorylation of PAK IEA Drosophila melanogaster A0A0B4KG38 R-DME-399944 https://reactome.org/PathwayBrowser/#/R-DME-399944 Phosphorylation of CRMPs by Cdk5 IEA Drosophila melanogaster A0A0B4KG38 R-DME-399947 https://reactome.org/PathwayBrowser/#/R-DME-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Drosophila melanogaster A0A0B4KG38 R-DME-399951 https://reactome.org/PathwayBrowser/#/R-DME-399951 Phosphorylation of CRMPs by GSK3beta IEA Drosophila melanogaster A0A0B4KG38 R-DME-399952 https://reactome.org/PathwayBrowser/#/R-DME-399952 Phosphorylation of LIMK-1 by PAK IEA Drosophila melanogaster A0A0B4KG38 R-DME-416588 https://reactome.org/PathwayBrowser/#/R-DME-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Drosophila melanogaster A0A0B4KG38 R-DME-416594 https://reactome.org/PathwayBrowser/#/R-DME-416594 LARG and PDZ-RhoGEF binds to Plexin-B1 IEA Drosophila melanogaster A0A0B4KG38 R-DME-416683 https://reactome.org/PathwayBrowser/#/R-DME-416683 SEMA3E binds to PLXND1 IEA Drosophila melanogaster A0A0B4KG38 R-DME-416690 https://reactome.org/PathwayBrowser/#/R-DME-416690 SEMA4A binds to PLXND1 IEA Drosophila melanogaster A0A0B4KG38 R-DME-434989 https://reactome.org/PathwayBrowser/#/R-DME-434989 SEMA7A binds to PLXNC1 IEA Drosophila melanogaster A0A0B4KG59 R-DME-1181149 https://reactome.org/PathwayBrowser/#/R-DME-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Drosophila melanogaster A0A0B4KG59 R-DME-1181153 https://reactome.org/PathwayBrowser/#/R-DME-1181153 Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B IEA Drosophila melanogaster A0A0B4KG59 R-DME-1549526 https://reactome.org/PathwayBrowser/#/R-DME-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Drosophila melanogaster A0A0B4KG59 R-DME-170835 https://reactome.org/PathwayBrowser/#/R-DME-170835 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 IEA Drosophila melanogaster A0A0B4KG59 R-DME-170843 https://reactome.org/PathwayBrowser/#/R-DME-170843 TGFBR2 phosphorylates TGFBR1 IEA Drosophila melanogaster A0A0B4KG59 R-DME-170846 https://reactome.org/PathwayBrowser/#/R-DME-170846 TGFBR2 recruits TGFBR1 IEA Drosophila melanogaster A0A0B4KG59 R-DME-170850 https://reactome.org/PathwayBrowser/#/R-DME-170850 Phosphorylated SMAD2/3 dissociates from TGFBR IEA Drosophila melanogaster A0A0B4KG59 R-DME-170861 https://reactome.org/PathwayBrowser/#/R-DME-170861 Dimeric TGF-beta-1 binds to the receptor IEA Drosophila melanogaster A0A0B4KG59 R-DME-170868 https://reactome.org/PathwayBrowser/#/R-DME-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Drosophila melanogaster A0A0B4KG59 R-DME-173512 https://reactome.org/PathwayBrowser/#/R-DME-173512 I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) IEA Drosophila melanogaster A0A0B4KG59 R-DME-201443 https://reactome.org/PathwayBrowser/#/R-DME-201443 Type II receptor phosphorylates type I receptor IEA Drosophila melanogaster A0A0B4KG59 R-DME-201453 https://reactome.org/PathwayBrowser/#/R-DME-201453 Phospho-R-Smad1/5/8 dissociates from the receptor complex IEA Drosophila melanogaster A0A0B4KG59 R-DME-201457 https://reactome.org/PathwayBrowser/#/R-DME-201457 BMP2 binds to the receptor complex IEA Drosophila melanogaster A0A0B4KG59 R-DME-201475 https://reactome.org/PathwayBrowser/#/R-DME-201475 I-Smad competes with R-Smad1/5/8 for type I receptor IEA Drosophila melanogaster A0A0B4KG59 R-DME-201476 https://reactome.org/PathwayBrowser/#/R-DME-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Drosophila melanogaster A0A0B4KG59 R-DME-201648 https://reactome.org/PathwayBrowser/#/R-DME-201648 An anchoring protein, Endofin, recruits R-Smad1/5/8 IEA Drosophila melanogaster A0A0B4KG59 R-DME-201821 https://reactome.org/PathwayBrowser/#/R-DME-201821 I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated IEA Drosophila melanogaster A0A0B4KG59 R-DME-202604 https://reactome.org/PathwayBrowser/#/R-DME-202604 Formation of a heteromeric BMP receptor complex IEA Drosophila melanogaster A0A0B4KG59 R-DME-2128994 https://reactome.org/PathwayBrowser/#/R-DME-2128994 STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 IEA Drosophila melanogaster A0A0B4KG59 R-DME-2160931 https://reactome.org/PathwayBrowser/#/R-DME-2160931 Disassembly of tight junctions IEA Drosophila melanogaster A0A0B4KG59 R-DME-2160932 https://reactome.org/PathwayBrowser/#/R-DME-2160932 SMURF1 binds phosphorylated PARD6A IEA Drosophila melanogaster A0A0B4KG59 R-DME-2160935 https://reactome.org/PathwayBrowser/#/R-DME-2160935 SMURF1 ubiquitinates RHOA IEA Drosophila melanogaster A0A0B4KG59 R-DME-2169046 https://reactome.org/PathwayBrowser/#/R-DME-2169046 Degradation of TGF-beta receptor complex IEA Drosophila melanogaster A0A0B4KG59 R-DME-4332235 https://reactome.org/PathwayBrowser/#/R-DME-4332235 CBL binds TGFBR2 IEA Drosophila melanogaster A0A0B4KG59 R-DME-4332236 https://reactome.org/PathwayBrowser/#/R-DME-4332236 CBL neddylates TGFBR2 IEA Drosophila melanogaster A0A0B4KG59 R-DME-9839358 https://reactome.org/PathwayBrowser/#/R-DME-9839358 Endocytosis of TGFBR3:ARRB complex IEA Drosophila melanogaster A0A0B4KG70 R-DME-3465545 https://reactome.org/PathwayBrowser/#/R-DME-3465545 PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 IEA Drosophila melanogaster A0A0B4KG70 R-DME-3769447 https://reactome.org/PathwayBrowser/#/R-DME-3769447 HDAC1:2-containing complex deacetylate histones IEA Drosophila melanogaster A0A0B4KG70 R-DME-6805650 https://reactome.org/PathwayBrowser/#/R-DME-6805650 MTA2-NuRD complex deacetylates TP53 IEA Drosophila melanogaster A0A0B4KG70 R-DME-8943780 https://reactome.org/PathwayBrowser/#/R-DME-8943780 SALL4 recruits NuRD to PTEN gene IEA Drosophila melanogaster A0A0B4KG70 R-DME-9679787 https://reactome.org/PathwayBrowser/#/R-DME-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Drosophila melanogaster A0A0B4KG96 R-DME-72180 https://reactome.org/PathwayBrowser/#/R-DME-72180 Cleavage of mRNA at the 3'-end IEA Drosophila melanogaster A0A0B4KG96 R-DME-72185 https://reactome.org/PathwayBrowser/#/R-DME-72185 mRNA polyadenylation IEA Drosophila melanogaster A0A0B4KG96 R-DME-72231 https://reactome.org/PathwayBrowser/#/R-DME-72231 Formation of the Cleavage and Polyadenylation Complex IEA Drosophila melanogaster A0A0B4KG96 R-DME-77591 https://reactome.org/PathwayBrowser/#/R-DME-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Drosophila melanogaster A0A0B4KG96 R-DME-77592 https://reactome.org/PathwayBrowser/#/R-DME-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Drosophila melanogaster A0A0B4KG96 R-DME-77593 https://reactome.org/PathwayBrowser/#/R-DME-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Drosophila melanogaster A0A0B4KG96 R-DME-9933575 https://reactome.org/PathwayBrowser/#/R-DME-9933575 MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome IEA Drosophila melanogaster A0A0B4KGD9 R-DME-1250264 https://reactome.org/PathwayBrowser/#/R-DME-1250264 TXNIP binds reduced thioredoxin IEA Drosophila melanogaster A0A0B4KGE4 R-DME-352191 https://reactome.org/PathwayBrowser/#/R-DME-352191 SLC7A8-mediated uptake of neutral amino acids IEA Drosophila melanogaster A0A0B4KGE4 R-DME-352232 https://reactome.org/PathwayBrowser/#/R-DME-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Drosophila melanogaster A0A0B4KGE4 R-DME-375131 https://reactome.org/PathwayBrowser/#/R-DME-375131 Basigin binds CD98 complex IEA Drosophila melanogaster A0A0B4KGE4 R-DME-376200 https://reactome.org/PathwayBrowser/#/R-DME-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Drosophila melanogaster A0A0B4KGE4 R-DME-378513 https://reactome.org/PathwayBrowser/#/R-DME-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate IEA Drosophila melanogaster A0A0B4KGE4 R-DME-379415 https://reactome.org/PathwayBrowser/#/R-DME-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Drosophila melanogaster A0A0B4KGE4 R-DME-379426 https://reactome.org/PathwayBrowser/#/R-DME-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Drosophila melanogaster A0A0B4KGE5 R-DME-975040 https://reactome.org/PathwayBrowser/#/R-DME-975040 KRAB-ZNF / KAP Interaction IEA Drosophila melanogaster A0A0B4KGE5 R-DME-9842833 https://reactome.org/PathwayBrowser/#/R-DME-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Drosophila melanogaster A0A0B4KGE5 R-DME-9842839 https://reactome.org/PathwayBrowser/#/R-DME-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Drosophila melanogaster A0A0B4KGE5 R-DME-9843978 https://reactome.org/PathwayBrowser/#/R-DME-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Drosophila melanogaster A0A0B4KGG5 R-DME-1483087 https://reactome.org/PathwayBrowser/#/R-DME-1483087 PI is exchanged with PC by PITPNB IEA Drosophila melanogaster A0A0B4KGG5 R-DME-1483211 https://reactome.org/PathwayBrowser/#/R-DME-1483211 PC:PITPNB is transported from the Golgi membrane to the ER membrane IEA Drosophila melanogaster A0A0B4KGG5 R-DME-1483219 https://reactome.org/PathwayBrowser/#/R-DME-1483219 PC is exchanged with PI by PITPNB IEA Drosophila melanogaster A0A0B4KGG5 R-DME-1483229 https://reactome.org/PathwayBrowser/#/R-DME-1483229 PI:PITPNB is transported from the ER membrane to the Golgi membrane IEA Drosophila melanogaster A0A0B4KGI0 R-DME-1454916 https://reactome.org/PathwayBrowser/#/R-DME-1454916 The ABCC family mediates organic anion transport IEA Drosophila melanogaster A0A0B4KGI0 R-DME-383190 https://reactome.org/PathwayBrowser/#/R-DME-383190 HCO3- transport through ion channel IEA Drosophila melanogaster A0A0B4KGI0 R-DME-5678863 https://reactome.org/PathwayBrowser/#/R-DME-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Drosophila melanogaster A0A0B4KGI0 R-DME-8866277 https://reactome.org/PathwayBrowser/#/R-DME-8866277 AP-2 directly binds some endocytic cargo IEA Drosophila melanogaster A0A0B4KGI0 R-DME-8866546 https://reactome.org/PathwayBrowser/#/R-DME-8866546 RNF5 and RNF185 ubiquitinate misfolded CFTR IEA Drosophila melanogaster A0A0B4KGI0 R-DME-8866553 https://reactome.org/PathwayBrowser/#/R-DME-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Drosophila melanogaster A0A0B4KGI0 R-DME-8866851 https://reactome.org/PathwayBrowser/#/R-DME-8866851 CFTR transits to the plasma membrane IEA Drosophila melanogaster A0A0B4KGI0 R-DME-8867754 https://reactome.org/PathwayBrowser/#/R-DME-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Drosophila melanogaster A0A0B4KGI0 R-DME-8867756 https://reactome.org/PathwayBrowser/#/R-DME-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Drosophila melanogaster A0A0B4KGI0 R-DME-8868071 https://reactome.org/PathwayBrowser/#/R-DME-8868071 Clathrin recruits PIK3C2A IEA Drosophila melanogaster A0A0B4KGI0 R-DME-8868072 https://reactome.org/PathwayBrowser/#/R-DME-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Drosophila melanogaster A0A0B4KGI0 R-DME-8868236 https://reactome.org/PathwayBrowser/#/R-DME-8868236 BAR domain proteins recruit dynamin IEA Drosophila melanogaster A0A0B4KGI0 R-DME-8868648 https://reactome.org/PathwayBrowser/#/R-DME-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Drosophila melanogaster A0A0B4KGI0 R-DME-8868651 https://reactome.org/PathwayBrowser/#/R-DME-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Drosophila melanogaster A0A0B4KGI0 R-DME-8868658 https://reactome.org/PathwayBrowser/#/R-DME-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Drosophila melanogaster A0A0B4KGI0 R-DME-8868660 https://reactome.org/PathwayBrowser/#/R-DME-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Drosophila melanogaster A0A0B4KGI0 R-DME-8868661 https://reactome.org/PathwayBrowser/#/R-DME-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Drosophila melanogaster A0A0B4KGI0 R-DME-8871194 https://reactome.org/PathwayBrowser/#/R-DME-8871194 RAB5 and GAPVD1 bind AP-2 IEA Drosophila melanogaster A0A0B4KGI0 R-DME-9641109 https://reactome.org/PathwayBrowser/#/R-DME-9641109 PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 IEA Drosophila melanogaster A0A0B4KGI0 R-DME-9641111 https://reactome.org/PathwayBrowser/#/R-DME-9641111 Parkin transfers Ub to misfolded proteins IEA Drosophila melanogaster A0A0B4KGI0 R-DME-9641127 https://reactome.org/PathwayBrowser/#/R-DME-9641127 Ub:misfolded proteins polymerize to PolyUb:misfolded proteins IEA Drosophila melanogaster A0A0B4KGI0 R-DME-9646348 https://reactome.org/PathwayBrowser/#/R-DME-9646348 PolyUb-Misfolded Proteins:HDAC6 bind dynein motor IEA Drosophila melanogaster A0A0B4KGL0 R-DME-6794346 https://reactome.org/PathwayBrowser/#/R-DME-6794346 NRXNs bind NLGNs IEA Drosophila melanogaster A0A0B4KGL0 R-DME-6797554 https://reactome.org/PathwayBrowser/#/R-DME-6797554 ABP1 binds SHANK proteins IEA Drosophila melanogaster A0A0B4KGL0 R-DME-6797568 https://reactome.org/PathwayBrowser/#/R-DME-6797568 NRXNs bind CASK:Protein 4.1 IEA Drosophila melanogaster A0A0B4KGL0 R-DME-6797974 https://reactome.org/PathwayBrowser/#/R-DME-6797974 LRRTMs bind NRXNs IEA Drosophila melanogaster A0A0B4KGS4 R-DME-2730856 https://reactome.org/PathwayBrowser/#/R-DME-2730856 Autophosphorylation of PAK IEA Drosophila melanogaster A0A0B4KGS4 R-DME-2730889 https://reactome.org/PathwayBrowser/#/R-DME-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Drosophila melanogaster A0A0B4KGS4 R-DME-389788 https://reactome.org/PathwayBrowser/#/R-DME-389788 Activation of PAKs by RAC1 and CDC42 IEA Drosophila melanogaster A0A0B4KGS4 R-DME-3928625 https://reactome.org/PathwayBrowser/#/R-DME-3928625 PAKs autophosphorylate IEA Drosophila melanogaster A0A0B4KGS4 R-DME-3928640 https://reactome.org/PathwayBrowser/#/R-DME-3928640 PAKs phosphorylate MLC IEA Drosophila melanogaster A0A0B4KGS4 R-DME-3928641 https://reactome.org/PathwayBrowser/#/R-DME-3928641 PAK binds RAC and bPIX IEA Drosophila melanogaster A0A0B4KGS4 R-DME-399930 https://reactome.org/PathwayBrowser/#/R-DME-399930 Activation of PAK by Rac1 IEA Drosophila melanogaster A0A0B4KGS4 R-DME-399939 https://reactome.org/PathwayBrowser/#/R-DME-399939 Autophosphorylation of PAK IEA Drosophila melanogaster A0A0B4KGS4 R-DME-399952 https://reactome.org/PathwayBrowser/#/R-DME-399952 Phosphorylation of LIMK-1 by PAK IEA Drosophila melanogaster A0A0B4KGS4 R-DME-430183 https://reactome.org/PathwayBrowser/#/R-DME-430183 NCK binds PAK IEA Drosophila melanogaster A0A0B4KGS4 R-DME-5218804 https://reactome.org/PathwayBrowser/#/R-DME-5218804 p38 MAPK activation by VEGFR IEA Drosophila melanogaster A0A0B4KGS4 R-DME-5218812 https://reactome.org/PathwayBrowser/#/R-DME-5218812 FYN phosphorylates PAK2 IEA Drosophila melanogaster A0A0B4KGS4 R-DME-5218814 https://reactome.org/PathwayBrowser/#/R-DME-5218814 PAK2 autophorylates IEA Drosophila melanogaster A0A0B4KGS4 R-DME-5218832 https://reactome.org/PathwayBrowser/#/R-DME-5218832 CDC42:GTP binds PAK2 IEA Drosophila melanogaster A0A0B4KGS4 R-DME-5218847 https://reactome.org/PathwayBrowser/#/R-DME-5218847 PAK2 binds NCK IEA Drosophila melanogaster A0A0B4KGS4 R-DME-5357445 https://reactome.org/PathwayBrowser/#/R-DME-5357445 PAK1-3 dimer disassociates IEA Drosophila melanogaster A0A0B4KGS4 R-DME-5357472 https://reactome.org/PathwayBrowser/#/R-DME-5357472 PAK1-3 autophosphorylates IEA Drosophila melanogaster A0A0B4KGS4 R-DME-5357477 https://reactome.org/PathwayBrowser/#/R-DME-5357477 PAK1-3 phosphorylates VE-cadherin IEA Drosophila melanogaster A0A0B4KGS4 R-DME-5357483 https://reactome.org/PathwayBrowser/#/R-DME-5357483 RAC1 binds PAK1-3 IEA Drosophila melanogaster A0A0B4KGS4 R-DME-5624492 https://reactome.org/PathwayBrowser/#/R-DME-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Drosophila melanogaster A0A0B4KGS4 R-DME-5627775 https://reactome.org/PathwayBrowser/#/R-DME-5627775 Autophosphorylation of PAK1,2,3 IEA Drosophila melanogaster A0A0B4KGS4 R-DME-5668932 https://reactome.org/PathwayBrowser/#/R-DME-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Drosophila melanogaster A0A0B4KGS4 R-DME-8981926 https://reactome.org/PathwayBrowser/#/R-DME-8981926 RAC1 and CDC42 activate PAK3 IEA Drosophila melanogaster A0A0B4KGS4 R-DME-8981931 https://reactome.org/PathwayBrowser/#/R-DME-8981931 RAC1 and CDC42 activate PAK2 IEA Drosophila melanogaster A0A0B4KGS4 R-DME-9013145 https://reactome.org/PathwayBrowser/#/R-DME-9013145 RAC1 binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KGS4 R-DME-9014294 https://reactome.org/PathwayBrowser/#/R-DME-9014294 RAC2 binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KGS4 R-DME-9014449 https://reactome.org/PathwayBrowser/#/R-DME-9014449 RHOG binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KGS4 R-DME-9018746 https://reactome.org/PathwayBrowser/#/R-DME-9018746 RHOQ binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KGS4 R-DME-9018758 https://reactome.org/PathwayBrowser/#/R-DME-9018758 RHOH binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KGS4 R-DME-9018766 https://reactome.org/PathwayBrowser/#/R-DME-9018766 RHOU binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KGS4 R-DME-9018794 https://reactome.org/PathwayBrowser/#/R-DME-9018794 RHOV binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KGS4 R-DME-9018808 https://reactome.org/PathwayBrowser/#/R-DME-9018808 RAC3 binds effectors at the plasma membrane IEA Drosophila melanogaster A0A0B4KGU2 R-DME-8952630 https://reactome.org/PathwayBrowser/#/R-DME-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex IEA Drosophila melanogaster A0A0B4KGU2 R-DME-8952631 https://reactome.org/PathwayBrowser/#/R-DME-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Drosophila melanogaster A0A0B4KGU2 R-DME-8955241 https://reactome.org/PathwayBrowser/#/R-DME-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Drosophila melanogaster A0A0B4KGU2 R-DME-8956040 https://reactome.org/PathwayBrowser/#/R-DME-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Drosophila melanogaster A0A0B4KGU2 R-DME-983140 https://reactome.org/PathwayBrowser/#/R-DME-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Drosophila melanogaster A0A0B4KGU2 R-DME-983147 https://reactome.org/PathwayBrowser/#/R-DME-983147 Release of E3 from polyubiquitinated substrate IEA Drosophila melanogaster A0A0B4KGU2 R-DME-983156 https://reactome.org/PathwayBrowser/#/R-DME-983156 Polyubiquitination of substrate IEA Drosophila melanogaster A0A0B4KGU2 R-DME-983157 https://reactome.org/PathwayBrowser/#/R-DME-983157 Interaction of E3 with substrate and E2-Ub complex IEA Drosophila melanogaster A0A0B4KGW2 R-DME-9613213 https://reactome.org/PathwayBrowser/#/R-DME-9613213 NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression IEA Drosophila melanogaster A0A0B4KGW3 R-DME-429094 https://reactome.org/PathwayBrowser/#/R-DME-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Drosophila melanogaster A0A0B4KGZ0 R-DME-3769447 https://reactome.org/PathwayBrowser/#/R-DME-3769447 HDAC1:2-containing complex deacetylate histones IEA Drosophila melanogaster A0A0B4KGZ0 R-DME-427337 https://reactome.org/PathwayBrowser/#/R-DME-427337 MBD2 binds methylcytosine in chromatin IEA Drosophila melanogaster A0A0B4KGZ0 R-DME-6805650 https://reactome.org/PathwayBrowser/#/R-DME-6805650 MTA2-NuRD complex deacetylates TP53 IEA Drosophila melanogaster A0A0B4KGZ0 R-DME-8943780 https://reactome.org/PathwayBrowser/#/R-DME-8943780 SALL4 recruits NuRD to PTEN gene IEA Drosophila melanogaster A0A0B4KGZ0 R-DME-9679787 https://reactome.org/PathwayBrowser/#/R-DME-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Drosophila melanogaster A0A0B4KH03 R-DME-481044 https://reactome.org/PathwayBrowser/#/R-DME-481044 Surface deployment of platelet alpha granule membrane components IEA Drosophila melanogaster A0A0B4KH14 R-DME-6798745 https://reactome.org/PathwayBrowser/#/R-DME-6798745 Exocytosis of tertiary granule lumen proteins IEA Drosophila melanogaster A0A0B4KH14 R-DME-9647982 https://reactome.org/PathwayBrowser/#/R-DME-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Drosophila melanogaster A0A0B4KH28 R-DME-8867754 https://reactome.org/PathwayBrowser/#/R-DME-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Drosophila melanogaster A0A0B4KH28 R-DME-8868236 https://reactome.org/PathwayBrowser/#/R-DME-8868236 BAR domain proteins recruit dynamin IEA Drosophila melanogaster A0A0B4KH28 R-DME-8868648 https://reactome.org/PathwayBrowser/#/R-DME-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Drosophila melanogaster A0A0B4KH28 R-DME-8868651 https://reactome.org/PathwayBrowser/#/R-DME-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Drosophila melanogaster A0A0B4KH28 R-DME-8868658 https://reactome.org/PathwayBrowser/#/R-DME-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Drosophila melanogaster A0A0B4KH28 R-DME-8868660 https://reactome.org/PathwayBrowser/#/R-DME-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Drosophila melanogaster A0A0B4KH28 R-DME-8868661 https://reactome.org/PathwayBrowser/#/R-DME-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Drosophila melanogaster A0A0B4KH28 R-DME-8871194 https://reactome.org/PathwayBrowser/#/R-DME-8871194 RAB5 and GAPVD1 bind AP-2 IEA Drosophila melanogaster A0A0B4KH64 R-DME-159101 https://reactome.org/PathwayBrowser/#/R-DME-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Drosophila melanogaster A0A0B4KH64 R-DME-72180 https://reactome.org/PathwayBrowser/#/R-DME-72180 Cleavage of mRNA at the 3'-end IEA Drosophila melanogaster A0A0B4KH64 R-DME-72185 https://reactome.org/PathwayBrowser/#/R-DME-72185 mRNA polyadenylation IEA Drosophila melanogaster A0A0B4KH64 R-DME-75097 https://reactome.org/PathwayBrowser/#/R-DME-75097 Transport of the export-competent mRNP complex through the NPC IEA Drosophila melanogaster A0A0B4KH64 R-DME-75098 https://reactome.org/PathwayBrowser/#/R-DME-75098 mRNP complex dissociates from cytosolic face of NPC IEA Drosophila melanogaster A0A0B4KH64 R-DME-927832 https://reactome.org/PathwayBrowser/#/R-DME-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Drosophila melanogaster A0A0B4KH64 R-DME-927836 https://reactome.org/PathwayBrowser/#/R-DME-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Drosophila melanogaster A0A0B4KH64 R-DME-927889 https://reactome.org/PathwayBrowser/#/R-DME-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Drosophila melanogaster A0A0B4KH64 R-DME-9770141 https://reactome.org/PathwayBrowser/#/R-DME-9770141 Formation of the Spliceosomal C* complex IEA Drosophila melanogaster A0A0B4KH64 R-DME-9770236 https://reactome.org/PathwayBrowser/#/R-DME-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Drosophila melanogaster A0A0B4KH64 R-DME-9794542 https://reactome.org/PathwayBrowser/#/R-DME-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Drosophila melanogaster A0A0B4KH68 R-DME-421831 https://reactome.org/PathwayBrowser/#/R-DME-421831 trans-Golgi Network Coat Assembly IEA Drosophila melanogaster A0A0B4KH68 R-DME-421833 https://reactome.org/PathwayBrowser/#/R-DME-421833 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture IEA Drosophila melanogaster A0A0B4KH68 R-DME-421835 https://reactome.org/PathwayBrowser/#/R-DME-421835 trans-Golgi Network Vesicle Scission IEA Drosophila melanogaster A0A0B4KH68 R-DME-6798743 https://reactome.org/PathwayBrowser/#/R-DME-6798743 Exocytosis of secretory granule membrane proteins IEA Drosophila melanogaster A0A0B4KH68 R-DME-6814670 https://reactome.org/PathwayBrowser/#/R-DME-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Drosophila melanogaster A0A0B4KH68 R-DME-6814674 https://reactome.org/PathwayBrowser/#/R-DME-6814674 Tethering of late endosome-derived vesicles by GARP, STX10:ST16:VTI1A and Golgins IEA Drosophila melanogaster A0A0B4KH68 R-DME-6814675 https://reactome.org/PathwayBrowser/#/R-DME-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Drosophila melanogaster A0A0B4KH68 R-DME-8866277 https://reactome.org/PathwayBrowser/#/R-DME-8866277 AP-2 directly binds some endocytic cargo IEA Drosophila melanogaster A0A0B4KH68 R-DME-8867754 https://reactome.org/PathwayBrowser/#/R-DME-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Drosophila melanogaster A0A0B4KH68 R-DME-8867756 https://reactome.org/PathwayBrowser/#/R-DME-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Drosophila melanogaster A0A0B4KH68 R-DME-8868071 https://reactome.org/PathwayBrowser/#/R-DME-8868071 Clathrin recruits PIK3C2A IEA Drosophila melanogaster A0A0B4KH68 R-DME-8868072 https://reactome.org/PathwayBrowser/#/R-DME-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Drosophila melanogaster A0A0B4KH68 R-DME-8868236 https://reactome.org/PathwayBrowser/#/R-DME-8868236 BAR domain proteins recruit dynamin IEA Drosophila melanogaster A0A0B4KH68 R-DME-8868648 https://reactome.org/PathwayBrowser/#/R-DME-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Drosophila melanogaster A0A0B4KH68 R-DME-8868651 https://reactome.org/PathwayBrowser/#/R-DME-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Drosophila melanogaster A0A0B4KH68 R-DME-8868658 https://reactome.org/PathwayBrowser/#/R-DME-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Drosophila melanogaster A0A0B4KH68 R-DME-8868660 https://reactome.org/PathwayBrowser/#/R-DME-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Drosophila melanogaster A0A0B4KH68 R-DME-8868661 https://reactome.org/PathwayBrowser/#/R-DME-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Drosophila melanogaster A0A0B4KH68 R-DME-8871194 https://reactome.org/PathwayBrowser/#/R-DME-8871194 RAB5 and GAPVD1 bind AP-2 IEA Drosophila melanogaster A0A0B4KH77 R-DME-2022399 https://reactome.org/PathwayBrowser/#/R-DME-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Drosophila melanogaster A0A0B4KH77 R-DME-983158 https://reactome.org/PathwayBrowser/#/R-DME-983158 Trimming of peptides in ER IEA Drosophila melanogaster A0A0B4KH77 R-DME-983162 https://reactome.org/PathwayBrowser/#/R-DME-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Drosophila melanogaster A0A0B4KH86 R-DME-1013012 https://reactome.org/PathwayBrowser/#/R-DME-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Drosophila melanogaster A0A0B4KH86 R-DME-1013020 https://reactome.org/PathwayBrowser/#/R-DME-1013020 Activation of GIRK/Kir3 Channels IEA Drosophila melanogaster A0A0B4KH86 R-DME-1296024 https://reactome.org/PathwayBrowser/#/R-DME-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Drosophila melanogaster A0A0B4KH86 R-DME-1296045 https://reactome.org/PathwayBrowser/#/R-DME-1296045 Activation of Potassium transport channels IEA Drosophila melanogaster A0A0B4KH86 R-DME-1296046 https://reactome.org/PathwayBrowser/#/R-DME-1296046 KCNJs transport K+ from the extracellular region to cytosol IEA Drosophila melanogaster A0A0B4KH86 R-DME-1369017 https://reactome.org/PathwayBrowser/#/R-DME-1369017 Activation of ATP sensitive Potassium channels in muscle cells IEA Drosophila melanogaster A0A0B4KH86 R-DME-265682 https://reactome.org/PathwayBrowser/#/R-DME-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Drosophila melanogaster A0A0B4KH86 R-DME-5678261 https://reactome.org/PathwayBrowser/#/R-DME-5678261 KCNJ11:ABCC9 transports K+ from extracellular region to cytosol IEA Drosophila melanogaster A0A0B4KH86 R-DME-9650858 https://reactome.org/PathwayBrowser/#/R-DME-9650858 Meglitinides bind ABCC8 IEA Drosophila melanogaster A0A0B4KH86 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster A0A0B4KH86 R-DME-9691566 https://reactome.org/PathwayBrowser/#/R-DME-9691566 KCNJ11:ABCC9 binds nicorandil IEA Drosophila melanogaster A0A0B4KHC3 R-DME-429698 https://reactome.org/PathwayBrowser/#/R-DME-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Drosophila melanogaster A0A0B4KHC8 R-DME-2187309 https://reactome.org/PathwayBrowser/#/R-DME-2187309 SMAD2/3:SMAD4 heterotrimer binds SP1 IEA Drosophila melanogaster A0A0B4KHC8 R-DME-6804468 https://reactome.org/PathwayBrowser/#/R-DME-6804468 PIAS1 SUMOylates SP3 with SUMO2 IEA Drosophila melanogaster A0A0B4KHC8 R-DME-6810233 https://reactome.org/PathwayBrowser/#/R-DME-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Drosophila melanogaster A0A0B4KHC8 R-DME-6810238 https://reactome.org/PathwayBrowser/#/R-DME-6810238 RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) IEA Drosophila melanogaster A0A0B4KHC8 R-DME-6814549 https://reactome.org/PathwayBrowser/#/R-DME-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Drosophila melanogaster A0A0B4KHC8 R-DME-6814555 https://reactome.org/PathwayBrowser/#/R-DME-6814555 Integrator complex processes the 3' end of snRNA IEA Drosophila melanogaster A0A0B4KHC8 R-DME-6814559 https://reactome.org/PathwayBrowser/#/R-DME-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Drosophila melanogaster A0A0B4KHC8 R-DME-6814885 https://reactome.org/PathwayBrowser/#/R-DME-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Drosophila melanogaster A0A0B4KHC8 R-DME-9023840 https://reactome.org/PathwayBrowser/#/R-DME-9023840 HATs and coactivators are recruited to the CTSD gene IEA Drosophila melanogaster A0A0B4KHC8 R-DME-9761027 https://reactome.org/PathwayBrowser/#/R-DME-9761027 ZEB2 binds SP1 IEA Drosophila melanogaster A0A0B4KHD0 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster A0A0B4KHD0 R-DME-390663 https://reactome.org/PathwayBrowser/#/R-DME-390663 ADRA2A,B,C bind ADR,NAd IEA Drosophila melanogaster A0A0B4KHD0 R-DME-400071 https://reactome.org/PathwayBrowser/#/R-DME-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline IEA Drosophila melanogaster A0A0B4KHD0 R-DME-400092 https://reactome.org/PathwayBrowser/#/R-DME-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Drosophila melanogaster A0A0B4KHD0 R-DME-749453 https://reactome.org/PathwayBrowser/#/R-DME-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Drosophila melanogaster A0A0B4KHD0 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster A0A0B4KHD0 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster A0A0B4KHD0 R-DME-9626914 https://reactome.org/PathwayBrowser/#/R-DME-9626914 α2-agonists bind ADRA2A,B,C IEA Drosophila melanogaster A0A0B4KHF0 R-DME-1562626 https://reactome.org/PathwayBrowser/#/R-DME-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Drosophila melanogaster A0A0B4KHF0 R-DME-5691107 https://reactome.org/PathwayBrowser/#/R-DME-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Drosophila melanogaster A0A0B4KHF0 R-DME-6798745 https://reactome.org/PathwayBrowser/#/R-DME-6798745 Exocytosis of tertiary granule lumen proteins IEA Drosophila melanogaster A0A0B4KHF0 R-DME-6798751 https://reactome.org/PathwayBrowser/#/R-DME-6798751 Exocytosis of azurophil granule lumen proteins IEA Drosophila melanogaster A0A0B4KHF0 R-DME-6800434 https://reactome.org/PathwayBrowser/#/R-DME-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Drosophila melanogaster A0A0B4KHF1 R-DME-8949178 https://reactome.org/PathwayBrowser/#/R-DME-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix IEA Drosophila melanogaster A0A0B4KHF1 R-DME-8953461 https://reactome.org/PathwayBrowser/#/R-DME-8953461 SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex IEA Drosophila melanogaster A0A0B4KHI4 R-DME-72103 https://reactome.org/PathwayBrowser/#/R-DME-72103 Formation of pre-mRNPs IEA Drosophila melanogaster A0A0B4KHI4 R-DME-9770141 https://reactome.org/PathwayBrowser/#/R-DME-9770141 Formation of the Spliceosomal C* complex IEA Drosophila melanogaster A0A0B4KHI4 R-DME-9770236 https://reactome.org/PathwayBrowser/#/R-DME-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Drosophila melanogaster A0A0B4KHI4 R-DME-9794542 https://reactome.org/PathwayBrowser/#/R-DME-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Drosophila melanogaster A0A0B4KHJ0 R-DME-451283 https://reactome.org/PathwayBrowser/#/R-DME-451283 kainate receptor binds glutamate IEA Drosophila melanogaster A0A0B4KHJ0 R-DME-451309 https://reactome.org/PathwayBrowser/#/R-DME-451309 Edited Kainate Receptor binds glutamate IEA Drosophila melanogaster A0A0B4KHJ0 R-DME-451310 https://reactome.org/PathwayBrowser/#/R-DME-451310 Activation of Edited Kainate receptors IEA Drosophila melanogaster A0A0B4KHJ0 R-DME-451311 https://reactome.org/PathwayBrowser/#/R-DME-451311 Activation of Ca-permeable Kainate receptors IEA Drosophila melanogaster A0A0B4KHK0 R-DME-1483002 https://reactome.org/PathwayBrowser/#/R-DME-1483002 DHAP is converted to 1-acyl GO3P by GNPAT IEA Drosophila melanogaster A0A0B4KHK0 R-DME-390427 https://reactome.org/PathwayBrowser/#/R-DME-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Drosophila melanogaster A0A0B4KHK0 R-DME-75879 https://reactome.org/PathwayBrowser/#/R-DME-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Drosophila melanogaster A0A0B4KHK0 R-DME-9033235 https://reactome.org/PathwayBrowser/#/R-DME-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Drosophila melanogaster A0A0B4KHK0 R-DME-9033236 https://reactome.org/PathwayBrowser/#/R-DME-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Drosophila melanogaster A0A0B4KHK8 R-DME-352232 https://reactome.org/PathwayBrowser/#/R-DME-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol IEA Drosophila melanogaster A0A0B4KHK8 R-DME-375131 https://reactome.org/PathwayBrowser/#/R-DME-375131 Basigin binds CD98 complex IEA Drosophila melanogaster A0A0B4KHK8 R-DME-376200 https://reactome.org/PathwayBrowser/#/R-DME-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Drosophila melanogaster A0A0B4KHK8 R-DME-378513 https://reactome.org/PathwayBrowser/#/R-DME-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate IEA Drosophila melanogaster A0A0B4KHK8 R-DME-379415 https://reactome.org/PathwayBrowser/#/R-DME-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane IEA Drosophila melanogaster A0A0B4KHK8 R-DME-379426 https://reactome.org/PathwayBrowser/#/R-DME-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine IEA Drosophila melanogaster A0A0B4KHL4 R-DME-429714 https://reactome.org/PathwayBrowser/#/R-DME-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Drosophila melanogaster A0A0B4KHL5 R-DME-481007 https://reactome.org/PathwayBrowser/#/R-DME-481007 Exocytosis of platelet alpha granule contents IEA Drosophila melanogaster A0A0B4KHR2 R-DME-5672966 https://reactome.org/PathwayBrowser/#/R-DME-5672966 RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers IEA Drosophila melanogaster A0A0B4KHR2 R-DME-5674018 https://reactome.org/PathwayBrowser/#/R-DME-5674018 BRAP binds RAS:GTP IEA Drosophila melanogaster A0A0B4KHR2 R-DME-5674019 https://reactome.org/PathwayBrowser/#/R-DME-5674019 BRAP binds KSR1:MARK3 IEA Drosophila melanogaster A0A0B4KHR2 R-DME-5674022 https://reactome.org/PathwayBrowser/#/R-DME-5674022 BRAP autoubiquitinates IEA Drosophila melanogaster A0A0B4KHZ2 R-DME-5690790 https://reactome.org/PathwayBrowser/#/R-DME-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Drosophila melanogaster A0A0B4KHZ4 R-DME-426240 https://reactome.org/PathwayBrowser/#/R-DME-426240 DAG kinase produces phosphatidic acid from DAG IEA Drosophila melanogaster A0A0B4KHZ9 R-DME-9821931 https://reactome.org/PathwayBrowser/#/R-DME-9821931 BOD1L1 binds SET1A complex IEA Drosophila melanogaster A0A0B4KI27 R-DME-1562626 https://reactome.org/PathwayBrowser/#/R-DME-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Drosophila melanogaster A0A0B4KI27 R-DME-5691107 https://reactome.org/PathwayBrowser/#/R-DME-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Drosophila melanogaster A0A0B4KI27 R-DME-6798745 https://reactome.org/PathwayBrowser/#/R-DME-6798745 Exocytosis of tertiary granule lumen proteins IEA Drosophila melanogaster A0A0B4KI27 R-DME-6798751 https://reactome.org/PathwayBrowser/#/R-DME-6798751 Exocytosis of azurophil granule lumen proteins IEA Drosophila melanogaster A0A0B4KI27 R-DME-6800434 https://reactome.org/PathwayBrowser/#/R-DME-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Drosophila melanogaster A0A0B4KI34 R-DME-182986 https://reactome.org/PathwayBrowser/#/R-DME-182986 CBL-mediated ubiquitination of CIN85 IEA Drosophila melanogaster A0A0B4KI34 R-DME-182990 https://reactome.org/PathwayBrowser/#/R-DME-182990 Sprouty sequesters CBL away from active EGFR IEA Drosophila melanogaster A0A0B4KI34 R-DME-182994 https://reactome.org/PathwayBrowser/#/R-DME-182994 Assembly of EGFR complex in clathrin-coated vesicles IEA Drosophila melanogaster A0A0B4KI34 R-DME-183002 https://reactome.org/PathwayBrowser/#/R-DME-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Drosophila melanogaster A0A0B4KI34 R-DME-183072 https://reactome.org/PathwayBrowser/#/R-DME-183072 EGFR non-clathrin mediated endocytosis IEA Drosophila melanogaster A0A0B4KI34 R-DME-8866279 https://reactome.org/PathwayBrowser/#/R-DME-8866279 Epsin family proteins bind ubiquitinated cargo IEA Drosophila melanogaster A0A0B4KI34 R-DME-8867041 https://reactome.org/PathwayBrowser/#/R-DME-8867041 EGFR phosphorylates EPS15 IEA Drosophila melanogaster A0A0B4KI34 R-DME-8867044 https://reactome.org/PathwayBrowser/#/R-DME-8867044 EGFR binds EPS15, EPN1, EPS15L1 IEA Drosophila melanogaster A0A0B4KI34 R-DME-8867047 https://reactome.org/PathwayBrowser/#/R-DME-8867047 PTPN3 dephosphorylates EPS15 IEA Drosophila melanogaster A0A0B4KI34 R-DME-8867754 https://reactome.org/PathwayBrowser/#/R-DME-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Drosophila melanogaster A0A0B4KI34 R-DME-8867756 https://reactome.org/PathwayBrowser/#/R-DME-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Drosophila melanogaster A0A0B4KI34 R-DME-8868071 https://reactome.org/PathwayBrowser/#/R-DME-8868071 Clathrin recruits PIK3C2A IEA Drosophila melanogaster A0A0B4KI34 R-DME-8868072 https://reactome.org/PathwayBrowser/#/R-DME-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Drosophila melanogaster A0A0B4KI34 R-DME-8868236 https://reactome.org/PathwayBrowser/#/R-DME-8868236 BAR domain proteins recruit dynamin IEA Drosophila melanogaster A0A0B4KI34 R-DME-8868648 https://reactome.org/PathwayBrowser/#/R-DME-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Drosophila melanogaster A0A0B4KI34 R-DME-8868651 https://reactome.org/PathwayBrowser/#/R-DME-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Drosophila melanogaster A0A0B4KI34 R-DME-8868658 https://reactome.org/PathwayBrowser/#/R-DME-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Drosophila melanogaster A0A0B4KI34 R-DME-8868660 https://reactome.org/PathwayBrowser/#/R-DME-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Drosophila melanogaster A0A0B4KI34 R-DME-8868661 https://reactome.org/PathwayBrowser/#/R-DME-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Drosophila melanogaster A0A0B4KI34 R-DME-8871194 https://reactome.org/PathwayBrowser/#/R-DME-8871194 RAB5 and GAPVD1 bind AP-2 IEA Drosophila melanogaster A0A0B4KI34 R-DME-8951490 https://reactome.org/PathwayBrowser/#/R-DME-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Drosophila melanogaster A0A0B4KI44 R-DME-8955241 https://reactome.org/PathwayBrowser/#/R-DME-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Drosophila melanogaster A0A0B4KI44 R-DME-8956040 https://reactome.org/PathwayBrowser/#/R-DME-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Drosophila melanogaster A0A0B4KI51 R-DME-9932443 https://reactome.org/PathwayBrowser/#/R-DME-9932443 BICRA, BICRAL and BRD9 bind SMARCC dimer:SMARCDs IEA Drosophila melanogaster A0A0B4KI51 R-DME-9933236 https://reactome.org/PathwayBrowser/#/R-DME-9933236 SS18-containing ATPase complex binds SMARCC dimer:SMARCDs:BICRAs:BRD9 IEA Drosophila melanogaster A0A0B4LES9 R-DME-162830 https://reactome.org/PathwayBrowser/#/R-DME-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate IEA Drosophila melanogaster A0A0B4LEZ1 R-DME-204008 https://reactome.org/PathwayBrowser/#/R-DME-204008 SEC31:SEC13 and v-SNARE recruitment IEA Drosophila melanogaster A0A0B4LEZ1 R-DME-5694409 https://reactome.org/PathwayBrowser/#/R-DME-5694409 Nucleotide exchange on RAB1 IEA Drosophila melanogaster A0A0B4LEZ1 R-DME-5694418 https://reactome.org/PathwayBrowser/#/R-DME-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Drosophila melanogaster A0A0B4LEZ1 R-DME-5694439 https://reactome.org/PathwayBrowser/#/R-DME-5694439 COPII coat binds TRAPPCII and RAB1:GDP IEA Drosophila melanogaster A0A0B4LFF4 R-DME-204392 https://reactome.org/PathwayBrowser/#/R-DME-204392 Basigin binds MCT1, MCT3 and MCT4 IEA Drosophila melanogaster A0A0B4LFF4 R-DME-373867 https://reactome.org/PathwayBrowser/#/R-DME-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Drosophila melanogaster A0A0B4LFF4 R-DME-373875 https://reactome.org/PathwayBrowser/#/R-DME-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Drosophila melanogaster A0A0B4LFF4 R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster A0A0B4LFF4 R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster A0A0B4LFW5 R-DME-3322001 https://reactome.org/PathwayBrowser/#/R-DME-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Drosophila melanogaster A0A0B4LFW5 R-DME-3322003 https://reactome.org/PathwayBrowser/#/R-DME-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Drosophila melanogaster A0A0B4LFW5 R-DME-3322005 https://reactome.org/PathwayBrowser/#/R-DME-3322005 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a IEA Drosophila melanogaster A0A0B4LFW5 R-DME-3322009 https://reactome.org/PathwayBrowser/#/R-DME-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Drosophila melanogaster A0A0B4LFW5 R-DME-3322014 https://reactome.org/PathwayBrowser/#/R-DME-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Drosophila melanogaster A0A0B4LFW5 R-DME-3322016 https://reactome.org/PathwayBrowser/#/R-DME-3322016 GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a IEA Drosophila melanogaster A0A0B4LFW5 R-DME-3322019 https://reactome.org/PathwayBrowser/#/R-DME-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Drosophila melanogaster A0A0B4LFW5 R-DME-3322025 https://reactome.org/PathwayBrowser/#/R-DME-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Drosophila melanogaster A0A0B4LFW5 R-DME-3322041 https://reactome.org/PathwayBrowser/#/R-DME-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Drosophila melanogaster A0A0B4LFW5 R-DME-3322057 https://reactome.org/PathwayBrowser/#/R-DME-3322057 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b IEA Drosophila melanogaster A0A0B4LFW5 R-DME-3780994 https://reactome.org/PathwayBrowser/#/R-DME-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Drosophila melanogaster A0A0B4LFW5 R-DME-3780997 https://reactome.org/PathwayBrowser/#/R-DME-3780997 PPP1R3C binds to glycogen:GYG2:GYS2 IEA Drosophila melanogaster A0A0B4LFW5 R-DME-3781011 https://reactome.org/PathwayBrowser/#/R-DME-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Drosophila melanogaster A0A0B4LFW5 R-DME-3781018 https://reactome.org/PathwayBrowser/#/R-DME-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Drosophila melanogaster A0A0B4LFW5 R-DME-3781023 https://reactome.org/PathwayBrowser/#/R-DME-3781023 PPP1R3C binds to glycogen:GYG1:GYS1 IEA Drosophila melanogaster A0A0B4LFW5 R-DME-3781024 https://reactome.org/PathwayBrowser/#/R-DME-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Drosophila melanogaster A0A0B4LFW5 R-DME-6798748 https://reactome.org/PathwayBrowser/#/R-DME-6798748 Exocytosis of secretory granule lumen proteins IEA Drosophila melanogaster A0A0B4LFW5 R-DME-6800434 https://reactome.org/PathwayBrowser/#/R-DME-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Drosophila melanogaster A0A0B4LFW5 R-DME-71552 https://reactome.org/PathwayBrowser/#/R-DME-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin IEA Drosophila melanogaster A0A0B4LFW5 R-DME-71593 https://reactome.org/PathwayBrowser/#/R-DME-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Drosophila melanogaster A0A0B4LFY9 R-DME-1964496 https://reactome.org/PathwayBrowser/#/R-DME-1964496 STING binds TRIM32 or TRIM56 IEA Drosophila melanogaster A0A0B4LFY9 R-DME-2396009 https://reactome.org/PathwayBrowser/#/R-DME-2396009 STING binds c-di-GMP IEA Drosophila melanogaster A0A0B4LFY9 R-DME-3134800 https://reactome.org/PathwayBrowser/#/R-DME-3134800 STING dimerization IEA Drosophila melanogaster A0A0B4LFY9 R-DME-3134804 https://reactome.org/PathwayBrowser/#/R-DME-3134804 STING ubiquitination by TRIM32 or TRIM56 IEA Drosophila melanogaster A0A0B4LFY9 R-DME-3244643 https://reactome.org/PathwayBrowser/#/R-DME-3244643 STING binds cyclic GMP-AMP IEA Drosophila melanogaster A0A0B4LFY9 R-DME-3249371 https://reactome.org/PathwayBrowser/#/R-DME-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Drosophila melanogaster A0A0B4LFY9 R-DME-3249378 https://reactome.org/PathwayBrowser/#/R-DME-3249378 STING recruits TBK1 and STAT6 IEA Drosophila melanogaster A0A0B4LFY9 R-DME-3249390 https://reactome.org/PathwayBrowser/#/R-DME-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Drosophila melanogaster A0A0B4LFY9 R-DME-6798743 https://reactome.org/PathwayBrowser/#/R-DME-6798743 Exocytosis of secretory granule membrane proteins IEA Drosophila melanogaster A0A0B4LGA2 R-DME-75079 https://reactome.org/PathwayBrowser/#/R-DME-75079 Formation of AT-AC C complex IEA Drosophila melanogaster A0A0B4LGA2 R-DME-75081 https://reactome.org/PathwayBrowser/#/R-DME-75081 Formation of AT-AC B Complex IEA Drosophila melanogaster A0A0B4LGA2 R-DME-75082 https://reactome.org/PathwayBrowser/#/R-DME-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Drosophila melanogaster A0A0B4LGD3 R-DME-426155 https://reactome.org/PathwayBrowser/#/R-DME-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Drosophila melanogaster A0A0B4LGH8 R-DME-8867667 https://reactome.org/PathwayBrowser/#/R-DME-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Drosophila melanogaster A0A0B4LGJ9 R-DME-549112 https://reactome.org/PathwayBrowser/#/R-DME-549112 G3P is acylated to 1-acyl LPA by AGPAT6 IEA Drosophila melanogaster A0A0B4LGJ9 R-DME-75885 https://reactome.org/PathwayBrowser/#/R-DME-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Drosophila melanogaster A0A0B4LGM5 R-DME-2993799 https://reactome.org/PathwayBrowser/#/R-DME-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Drosophila melanogaster A0A0B4LGM5 R-DME-2993802 https://reactome.org/PathwayBrowser/#/R-DME-2993802 HLCS biotinylates PC:Mn2+ IEA Drosophila melanogaster A0A0B4LGM5 R-DME-2993814 https://reactome.org/PathwayBrowser/#/R-DME-2993814 HLCS biotinylates ACACA:Mn2+ IEA Drosophila melanogaster A0A0B4LGM5 R-DME-4167511 https://reactome.org/PathwayBrowser/#/R-DME-4167511 HLCS biotinylates ACACB IEA Drosophila melanogaster A0A0B4LH09 R-DME-1008200 https://reactome.org/PathwayBrowser/#/R-DME-1008200 NFE2 binds the beta globin locus control region IEA Drosophila melanogaster A0A0B4LH09 R-DME-9707523 https://reactome.org/PathwayBrowser/#/R-DME-9707523 Hemes bind to BACH1:MAFK IEA Drosophila melanogaster A0A0B4LH09 R-DME-9707690 https://reactome.org/PathwayBrowser/#/R-DME-9707690 BACH1 binds MAFK IEA Drosophila melanogaster A0A0B4LH09 R-DME-9708557 https://reactome.org/PathwayBrowser/#/R-DME-9708557 FBXL17 binds BACH1:MAFK IEA Drosophila melanogaster A0A0B4LHI9 R-DME-1013012 https://reactome.org/PathwayBrowser/#/R-DME-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Drosophila melanogaster A0A0B4LHI9 R-DME-1013020 https://reactome.org/PathwayBrowser/#/R-DME-1013020 Activation of GIRK/Kir3 Channels IEA Drosophila melanogaster A0A0B4LHI9 R-DME-1296024 https://reactome.org/PathwayBrowser/#/R-DME-1296024 Activation of ATP sensitive Potassium channels in neuroendocrine cells IEA Drosophila melanogaster A0A0B4LHI9 R-DME-1296045 https://reactome.org/PathwayBrowser/#/R-DME-1296045 Activation of Potassium transport channels IEA Drosophila melanogaster A0A0B4LHI9 R-DME-1296046 https://reactome.org/PathwayBrowser/#/R-DME-1296046 KCNJs transport K+ from the extracellular region to cytosol IEA Drosophila melanogaster A0A0B4LHI9 R-DME-1369017 https://reactome.org/PathwayBrowser/#/R-DME-1369017 Activation of ATP sensitive Potassium channels in muscle cells IEA Drosophila melanogaster A0A0B4LHI9 R-DME-265682 https://reactome.org/PathwayBrowser/#/R-DME-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Drosophila melanogaster A0A0B4LHI9 R-DME-5678261 https://reactome.org/PathwayBrowser/#/R-DME-5678261 KCNJ11:ABCC9 transports K+ from extracellular region to cytosol IEA Drosophila melanogaster A0A0B4LHI9 R-DME-9650858 https://reactome.org/PathwayBrowser/#/R-DME-9650858 Meglitinides bind ABCC8 IEA Drosophila melanogaster A0A0B4LHI9 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster A0A0B4LHI9 R-DME-9691566 https://reactome.org/PathwayBrowser/#/R-DME-9691566 KCNJ11:ABCC9 binds nicorandil IEA Drosophila melanogaster A0A0B4LHR4 R-DME-1013012 https://reactome.org/PathwayBrowser/#/R-DME-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Drosophila melanogaster A0A0B4LHR4 R-DME-1013013 https://reactome.org/PathwayBrowser/#/R-DME-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Drosophila melanogaster A0A0B4LHR4 R-DME-1013020 https://reactome.org/PathwayBrowser/#/R-DME-1013020 Activation of GIRK/Kir3 Channels IEA Drosophila melanogaster A0A0B4LHR4 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster A0A0B4LHR4 R-DME-420688 https://reactome.org/PathwayBrowser/#/R-DME-420688 GABAB heterodimeric receptor binds GABA IEA Drosophila melanogaster A0A0B4LHR4 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster A0A0B4LHR4 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster A0A0B4LHR8 R-DME-8871366 https://reactome.org/PathwayBrowser/#/R-DME-8871366 p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP IEA Drosophila melanogaster A0A0B4LHR8 R-DME-8871370 https://reactome.org/PathwayBrowser/#/R-DME-8871370 p-Y389,400-RUFY1 translocates from cytosol to early endosome membrane IEA Drosophila melanogaster A0A0B4LHR8 R-DME-8871373 https://reactome.org/PathwayBrowser/#/R-DME-8871373 BMX phosphorylates RUFY1 IEA Drosophila melanogaster A0A0B4LHR8 R-DME-8871376 https://reactome.org/PathwayBrowser/#/R-DME-8871376 p-Y389,400-RUFY1 binds PI3P IEA Drosophila melanogaster A0A0B4LHU7 R-DME-3321805 https://reactome.org/PathwayBrowser/#/R-DME-3321805 NSL acetylates histone H4 IEA Drosophila melanogaster A0A0B4LHU7 R-DME-9828175 https://reactome.org/PathwayBrowser/#/R-DME-9828175 Formation of the NSL complex IEA Drosophila melanogaster A0A0B4LHY5 R-DME-1433506 https://reactome.org/PathwayBrowser/#/R-DME-1433506 Phosphorylation of APS IEA Drosophila melanogaster A0A0B4LHY5 R-DME-205244 https://reactome.org/PathwayBrowser/#/R-DME-205244 Recruitment of CBL to KIT IEA Drosophila melanogaster A0A0B4LHY5 R-DME-997237 https://reactome.org/PathwayBrowser/#/R-DME-997237 SH2B proteins bind JAK2 IEA Drosophila melanogaster A0A0B4LID7 R-DME-9838035 https://reactome.org/PathwayBrowser/#/R-DME-9838035 CLPXP binds mitochondrial matrix proteins IEA Drosophila melanogaster A0A0B4LID7 R-DME-9838289 https://reactome.org/PathwayBrowser/#/R-DME-9838289 CLPXP degrades mitochondrial matrix proteins IEA Drosophila melanogaster A0A0B5H7I8 R-GGA-1678842 https://reactome.org/PathwayBrowser/#/R-GGA-1678842 Competitive inhibition of translation initiation by ISGylated 4EHP IEA Gallus gallus A0A0B5H7I8 R-GGA-5653756 https://reactome.org/PathwayBrowser/#/R-GGA-5653756 TRIM25 binds monoUb:164-PCNA IEA Gallus gallus A0A0C3SFZ3 R-GGA-204392 https://reactome.org/PathwayBrowser/#/R-GGA-204392 Basigin binds MCT1, MCT3 and MCT4 IEA Gallus gallus A0A0C3SFZ3 R-GGA-373867 https://reactome.org/PathwayBrowser/#/R-GGA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Gallus gallus A0A0C3SFZ3 R-GGA-373875 https://reactome.org/PathwayBrowser/#/R-GGA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Gallus gallus A0A0C3SFZ3 R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus A0A0C4DH25 R-HSA-1112666 https://reactome.org/PathwayBrowser/#/R-HSA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate TAS Homo sapiens A0A0C4DH25 R-HSA-166753 https://reactome.org/PathwayBrowser/#/R-HSA-166753 Conversion of C4 into C4a and C4b TAS Homo sapiens A0A0C4DH25 R-HSA-166792 https://reactome.org/PathwayBrowser/#/R-HSA-166792 Conversion of C2 into C2a and C2b TAS Homo sapiens A0A0C4DH25 R-HSA-173626 https://reactome.org/PathwayBrowser/#/R-HSA-173626 Activation of C1r TAS Homo sapiens A0A0C4DH25 R-HSA-173631 https://reactome.org/PathwayBrowser/#/R-HSA-173631 Activation of C1s TAS Homo sapiens A0A0C4DH25 R-HSA-1861621 https://reactome.org/PathwayBrowser/#/R-HSA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag TAS Homo sapiens A0A0C4DH25 R-HSA-199161 https://reactome.org/PathwayBrowser/#/R-HSA-199161 Fc gamma receptors interact with antigen-bound IgG TAS Homo sapiens A0A0C4DH25 R-HSA-2029268 https://reactome.org/PathwayBrowser/#/R-HSA-2029268 Phosphorylation and activation of PLCG TAS Homo sapiens A0A0C4DH25 R-HSA-2029270 https://reactome.org/PathwayBrowser/#/R-HSA-2029270 Recruitment of PLCgamma to membrane TAS Homo sapiens A0A0C4DH25 R-HSA-2029271 https://reactome.org/PathwayBrowser/#/R-HSA-2029271 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens A0A0C4DH25 R-HSA-2029272 https://reactome.org/PathwayBrowser/#/R-HSA-2029272 Release of PLCG from FCGR TAS Homo sapiens A0A0C4DH25 R-HSA-2029273 https://reactome.org/PathwayBrowser/#/R-HSA-2029273 PI3K binds to p-6Y-SYK TAS Homo sapiens A0A0C4DH25 R-HSA-2029449 https://reactome.org/PathwayBrowser/#/R-HSA-2029449 Phosphorylation of SYK by Src kinases IEA Homo sapiens A0A0C4DH25 R-HSA-2029451 https://reactome.org/PathwayBrowser/#/R-HSA-2029451 Activation of RAC1 by VAV TAS Homo sapiens A0A0C4DH25 R-HSA-2029452 https://reactome.org/PathwayBrowser/#/R-HSA-2029452 Recruitment of SYK to phosphorylated ITAMs TAS Homo sapiens A0A0C4DH25 R-HSA-2029453 https://reactome.org/PathwayBrowser/#/R-HSA-2029453 Phosphorylation of VAV TAS Homo sapiens A0A0C4DH25 R-HSA-2029455 https://reactome.org/PathwayBrowser/#/R-HSA-2029455 Cross-linking of FCGRIA with IgG-coated Ag TAS Homo sapiens A0A0C4DH25 R-HSA-2029457 https://reactome.org/PathwayBrowser/#/R-HSA-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag TAS Homo sapiens A0A0C4DH25 R-HSA-2029458 https://reactome.org/PathwayBrowser/#/R-HSA-2029458 Recruitment of VAV1 to p-6Y-SYK TAS Homo sapiens A0A0C4DH25 R-HSA-2029459 https://reactome.org/PathwayBrowser/#/R-HSA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts TAS Homo sapiens A0A0C4DH25 R-HSA-2029467 https://reactome.org/PathwayBrowser/#/R-HSA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO TAS Homo sapiens A0A0C4DH25 R-HSA-2029476 https://reactome.org/PathwayBrowser/#/R-HSA-2029476 Role of myosins in phagosome formation TAS Homo sapiens A0A0C4DH25 R-HSA-2197697 https://reactome.org/PathwayBrowser/#/R-HSA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR TAS Homo sapiens A0A0C4DH25 R-HSA-2203516 https://reactome.org/PathwayBrowser/#/R-HSA-2203516 Alpha-1-Microglobulin is cleaved TAS Homo sapiens A0A0C4DH25 R-HSA-2454192 https://reactome.org/PathwayBrowser/#/R-HSA-2454192 Allergen dependent IgE bound FCERI aggregation TAS Homo sapiens A0A0C4DH25 R-HSA-2454208 https://reactome.org/PathwayBrowser/#/R-HSA-2454208 Phosphorylation of beta and gamma subunits by LYN TAS Homo sapiens A0A0C4DH25 R-HSA-2454239 https://reactome.org/PathwayBrowser/#/R-HSA-2454239 Phosphorylation of SYK IEA Homo sapiens A0A0C4DH25 R-HSA-2454240 https://reactome.org/PathwayBrowser/#/R-HSA-2454240 Recruitment of SYK to p-FCERI gamma subunit TAS Homo sapiens A0A0C4DH25 R-HSA-2730833 https://reactome.org/PathwayBrowser/#/R-HSA-2730833 Phosphorylation of TEC kinases by p-SYK TAS Homo sapiens A0A0C4DH25 R-HSA-2730843 https://reactome.org/PathwayBrowser/#/R-HSA-2730843 Phosphorylation of LAT by p-SYK TAS Homo sapiens A0A0C4DH25 R-HSA-2730851 https://reactome.org/PathwayBrowser/#/R-HSA-2730851 Phosphorylation of SLP-76 by p-SYK TAS Homo sapiens A0A0C4DH25 R-HSA-2730860 https://reactome.org/PathwayBrowser/#/R-HSA-2730860 Phosphorylation of GAB2 by SYK/FYN IEA Homo sapiens A0A0C4DH25 R-HSA-2730882 https://reactome.org/PathwayBrowser/#/R-HSA-2730882 Phosphorylation of PKC-theta TAS Homo sapiens A0A0C4DH25 R-HSA-2730884 https://reactome.org/PathwayBrowser/#/R-HSA-2730884 Phosphorylation of NTAL by p-SYK/Lyn TAS Homo sapiens A0A0C4DH25 R-HSA-2730886 https://reactome.org/PathwayBrowser/#/R-HSA-2730886 Phosphorylation of SHC by SYK kinase TAS Homo sapiens A0A0C4DH25 R-HSA-2730888 https://reactome.org/PathwayBrowser/#/R-HSA-2730888 Phosphorylation of PLC-gamma IEA Homo sapiens A0A0C4DH25 R-HSA-5690701 https://reactome.org/PathwayBrowser/#/R-HSA-5690701 SHP1 binds p-CD22 TAS Homo sapiens A0A0C4DH25 R-HSA-5690702 https://reactome.org/PathwayBrowser/#/R-HSA-5690702 LYN phosphorylates CD22 TAS Homo sapiens A0A0C4DH25 R-HSA-5690740 https://reactome.org/PathwayBrowser/#/R-HSA-5690740 CD22 binds B-cell receptor TAS Homo sapiens A0A0C4DH25 R-HSA-8852266 https://reactome.org/PathwayBrowser/#/R-HSA-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s TAS Homo sapiens A0A0C4DH25 R-HSA-8852481 https://reactome.org/PathwayBrowser/#/R-HSA-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates TAS Homo sapiens A0A0C4DH25 R-HSA-8858428 https://reactome.org/PathwayBrowser/#/R-HSA-8858428 FCAMR binds IgA TAS Homo sapiens A0A0C4DH25 R-HSA-9021306 https://reactome.org/PathwayBrowser/#/R-HSA-9021306 C1-Inh binds and inactivates C1r, C1s TAS Homo sapiens A0A0C4DH25 R-HSA-9606151 https://reactome.org/PathwayBrowser/#/R-HSA-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 TAS Homo sapiens A0A0C4DH25 R-HSA-9606159 https://reactome.org/PathwayBrowser/#/R-HSA-9606159 BTK autophosphorylates IEA Homo sapiens A0A0C4DH25 R-HSA-9606162 https://reactome.org/PathwayBrowser/#/R-HSA-9606162 Phosphorylated BTK phosphorylates PLCG2 IEA Homo sapiens A0A0C4DH25 R-HSA-9606163 https://reactome.org/PathwayBrowser/#/R-HSA-9606163 p-SYK and LYN phosphorylate BTK IEA Homo sapiens A0A0C4DH25 R-HSA-9664261 https://reactome.org/PathwayBrowser/#/R-HSA-9664261 Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK TAS Homo sapiens A0A0C4DH25 R-HSA-9664268 https://reactome.org/PathwayBrowser/#/R-HSA-9664268 Opsonized leishmania amastigote binds FCGR3 TAS Homo sapiens A0A0C4DH25 R-HSA-9664270 https://reactome.org/PathwayBrowser/#/R-HSA-9664270 Recruitment of PLCgamma to membrane due to FCGR3A effect TAS Homo sapiens A0A0C4DH25 R-HSA-9664271 https://reactome.org/PathwayBrowser/#/R-HSA-9664271 Release of PLCG from FCGR3A TAS Homo sapiens A0A0C4DH25 R-HSA-9664273 https://reactome.org/PathwayBrowser/#/R-HSA-9664273 SYK binds IgG:Lma antigens:FCGR3A:p-CD3 dimers TAS Homo sapiens A0A0C4DH25 R-HSA-9664275 https://reactome.org/PathwayBrowser/#/R-HSA-9664275 Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers TAS Homo sapiens A0A0C4DH25 R-HSA-9664278 https://reactome.org/PathwayBrowser/#/R-HSA-9664278 Phosphorylation and activation of PLCG due to FCGR3A effect TAS Homo sapiens A0A0C4DH25 R-HSA-9664285 https://reactome.org/PathwayBrowser/#/R-HSA-9664285 IgG binds the surface of the amastigote form of Leishmania TAS Homo sapiens A0A0C4DH25 R-HSA-9664397 https://reactome.org/PathwayBrowser/#/R-HSA-9664397 IgG binds LPG1G2 in the amastigote form of Leishmania IEA Homo sapiens A0A0C4DH25 R-HSA-9664406 https://reactome.org/PathwayBrowser/#/R-HSA-9664406 IgG:Lma antigens binds FCGR3A:CD3 dimers TAS Homo sapiens A0A0C4DH25 R-HSA-9666425 https://reactome.org/PathwayBrowser/#/R-HSA-9666425 p-6Y-SYK phosphorylates VAV1,2,3 TAS Homo sapiens A0A0C4DH25 R-HSA-9666426 https://reactome.org/PathwayBrowser/#/R-HSA-9666426 CRKII:DOCK180:ELMO binds FCGR3A TAS Homo sapiens A0A0C4DH25 R-HSA-9666428 https://reactome.org/PathwayBrowser/#/R-HSA-9666428 DOCK180 exchanges GTP for GDP on RAC1:GDP TAS Homo sapiens A0A0C4DH25 R-HSA-9666430 https://reactome.org/PathwayBrowser/#/R-HSA-9666430 p-VAV1,2,3 exchanges GTP for GDP on RAC1:GDP TAS Homo sapiens A0A0C4DH25 R-HSA-9666433 https://reactome.org/PathwayBrowser/#/R-HSA-9666433 IgG binds the surface of the amastigote form of Leishmania TAS Homo sapiens A0A0C4DH25 R-HSA-9666435 https://reactome.org/PathwayBrowser/#/R-HSA-9666435 VAV1,2,3:PI(3,4,5)P3 binds p-6Y-SYK TAS Homo sapiens A0A0C4DH25 R-HSA-9666458 https://reactome.org/PathwayBrowser/#/R-HSA-9666458 IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole TAS Homo sapiens A0A0C4DH25 R-HSA-9691421 https://reactome.org/PathwayBrowser/#/R-HSA-9691421 BTK binds BTK inhibitors TAS Homo sapiens A0A0C4DH25 R-HSA-9724685 https://reactome.org/PathwayBrowser/#/R-HSA-9724685 IgE binds omalizumab TAS Homo sapiens A0A0C4DH25 R-HSA-9725206 https://reactome.org/PathwayBrowser/#/R-HSA-9725206 IgE binds FCERI TAS Homo sapiens A0A0C4DH25 R-HSA-983696 https://reactome.org/PathwayBrowser/#/R-HSA-983696 The Immunoglobulin of the BCR binds antigen TAS Homo sapiens A0A0C4DH25 R-HSA-983700 https://reactome.org/PathwayBrowser/#/R-HSA-983700 SYK binds the activated BCR TAS Homo sapiens A0A0C4DH25 R-HSA-983703 https://reactome.org/PathwayBrowser/#/R-HSA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) TAS Homo sapiens A0A0C4DH25 R-HSA-983707 https://reactome.org/PathwayBrowser/#/R-HSA-983707 SYK autophosphorylates at the activated BCR TAS Homo sapiens A0A0C4DH25 R-HSA-983709 https://reactome.org/PathwayBrowser/#/R-HSA-983709 LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B) IEA Homo sapiens A0A0C4DH73 R-HSA-1112666 https://reactome.org/PathwayBrowser/#/R-HSA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate TAS Homo sapiens A0A0C4DH73 R-HSA-166753 https://reactome.org/PathwayBrowser/#/R-HSA-166753 Conversion of C4 into C4a and C4b TAS Homo sapiens A0A0C4DH73 R-HSA-166792 https://reactome.org/PathwayBrowser/#/R-HSA-166792 Conversion of C2 into C2a and C2b TAS Homo sapiens A0A0C4DH73 R-HSA-173626 https://reactome.org/PathwayBrowser/#/R-HSA-173626 Activation of C1r TAS Homo sapiens A0A0C4DH73 R-HSA-173631 https://reactome.org/PathwayBrowser/#/R-HSA-173631 Activation of C1s TAS Homo sapiens A0A0C4DH73 R-HSA-1861621 https://reactome.org/PathwayBrowser/#/R-HSA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag TAS Homo sapiens A0A0C4DH73 R-HSA-199161 https://reactome.org/PathwayBrowser/#/R-HSA-199161 Fc gamma receptors interact with antigen-bound IgG TAS Homo sapiens A0A0C4DH73 R-HSA-2029268 https://reactome.org/PathwayBrowser/#/R-HSA-2029268 Phosphorylation and activation of PLCG TAS Homo sapiens A0A0C4DH73 R-HSA-2029270 https://reactome.org/PathwayBrowser/#/R-HSA-2029270 Recruitment of PLCgamma to membrane TAS Homo sapiens A0A0C4DH73 R-HSA-2029271 https://reactome.org/PathwayBrowser/#/R-HSA-2029271 PI3K phosphorylates PIP2 to PIP3 TAS Homo sapiens A0A0C4DH73 R-HSA-2029272 https://reactome.org/PathwayBrowser/#/R-HSA-2029272 Release of PLCG from FCGR TAS Homo sapiens A0A0C4DH73 R-HSA-2029273 https://reactome.org/PathwayBrowser/#/R-HSA-2029273 PI3K binds to p-6Y-SYK TAS Homo sapiens A0A0C4DH73 R-HSA-2029449 https://reactome.org/PathwayBrowser/#/R-HSA-2029449 Phosphorylation of SYK by Src kinases IEA Homo sapiens A0A0C4DH73 R-HSA-2029451 https://reactome.org/PathwayBrowser/#/R-HSA-2029451 Activation of RAC1 by VAV TAS Homo sapiens A0A0C4DH73 R-HSA-2029452 https://reactome.org/PathwayBrowser/#/R-HSA-2029452 Recruitment of SYK to phosphorylated ITAMs TAS Homo sapiens A0A0C4DH73 R-HSA-2029453 https://reactome.org/PathwayBrowser/#/R-HSA-2029453 Phosphorylation of VAV TAS Homo sapiens A0A0C4DH73 R-HSA-2029455 https://reactome.org/PathwayBrowser/#/R-HSA-2029455 Cross-linking of FCGRIA with IgG-coated Ag TAS Homo sapiens A0A0C4DH73 R-HSA-2029457 https://reactome.org/PathwayBrowser/#/R-HSA-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag TAS Homo sapiens A0A0C4DH73 R-HSA-2029458 https://reactome.org/PathwayBrowser/#/R-HSA-2029458 Recruitment of VAV1 to p-6Y-SYK TAS Homo sapiens A0A0C4DH73 R-HSA-2029459 https://reactome.org/PathwayBrowser/#/R-HSA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts TAS Homo sapiens A0A0C4DH73 R-HSA-2029467 https://reactome.org/PathwayBrowser/#/R-HSA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO TAS Homo sapiens A0A0C4DH73 R-HSA-2029476 https://reactome.org/PathwayBrowser/#/R-HSA-2029476 Role of myosins in phagosome formation TAS Homo sapiens A0A0C4DH73 R-HSA-2197697 https://reactome.org/PathwayBrowser/#/R-HSA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR TAS Homo sapiens A0A0C4DH73 R-HSA-2203516 https://reactome.org/PathwayBrowser/#/R-HSA-2203516 Alpha-1-Microglobulin is cleaved TAS Homo sapiens A0A0C4DH73 R-HSA-2454192 https://reactome.org/PathwayBrowser/#/R-HSA-2454192 Allergen dependent IgE bound FCERI aggregation TAS Homo sapiens A0A0C4DH73 R-HSA-2454208 https://reactome.org/PathwayBrowser/#/R-HSA-2454208 Phosphorylation of beta and gamma subunits by LYN TAS Homo sapiens A0A0C4DH73 R-HSA-2454239 https://reactome.org/PathwayBrowser/#/R-HSA-2454239 Phosphorylation of SYK IEA Homo sapiens A0A0C4DH73 R-HSA-2454240 https://reactome.org/PathwayBrowser/#/R-HSA-2454240 Recruitment of SYK to p-FCERI gamma subunit TAS Homo sapiens A0A0C4DH73 R-HSA-2730833 https://reactome.org/PathwayBrowser/#/R-HSA-2730833 Phosphorylation of TEC kinases by p-SYK TAS Homo sapiens A0A0C4DH73 R-HSA-2730843 https://reactome.org/PathwayBrowser/#/R-HSA-2730843 Phosphorylation of LAT by p-SYK TAS Homo sapiens A0A0C4DH73 R-HSA-2730851 https://reactome.org/PathwayBrowser/#/R-HSA-2730851 Phosphorylation of SLP-76 by p-SYK TAS Homo sapiens A0A0C4DH73 R-HSA-2730860 https://reactome.org/PathwayBrowser/#/R-HSA-2730860 Phosphorylation of GAB2 by SYK/FYN IEA Homo sapiens A0A0C4DH73 R-HSA-2730882 https://reactome.org/PathwayBrowser/#/R-HSA-2730882 Phosphorylation of PKC-theta TAS Homo sapiens A0A0C4DH73 R-HSA-2730884 https://reactome.org/PathwayBrowser/#/R-HSA-2730884 Phosphorylation of NTAL by p-SYK/Lyn TAS Homo sapiens A0A0C4DH73 R-HSA-2730886 https://reactome.org/PathwayBrowser/#/R-HSA-2730886 Phosphorylation of SHC by SYK kinase TAS Homo sapiens A0A0C4DH73 R-HSA-2730888 https://reactome.org/PathwayBrowser/#/R-HSA-2730888 Phosphorylation of PLC-gamma IEA Homo sapiens A0A0C4DH73 R-HSA-5690701 https://reactome.org/PathwayBrowser/#/R-HSA-5690701 SHP1 binds p-CD22 TAS Homo sapiens A0A0C4DH73 R-HSA-5690702 https://reactome.org/PathwayBrowser/#/R-HSA-5690702 LYN phosphorylates CD22 TAS Homo sapiens A0A0C4DH73 R-HSA-5690740 https://reactome.org/PathwayBrowser/#/R-HSA-5690740 CD22 binds B-cell receptor TAS Homo sapiens A0A0C4DH73 R-HSA-8852266 https://reactome.org/PathwayBrowser/#/R-HSA-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s TAS Homo sapiens A0A0C4DH73 R-HSA-8852481 https://reactome.org/PathwayBrowser/#/R-HSA-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates TAS Homo sapiens A0A0C4DH73 R-HSA-8858428 https://reactome.org/PathwayBrowser/#/R-HSA-8858428 FCAMR binds IgA TAS Homo sapiens A0A0C4DH73 R-HSA-9021306 https://reactome.org/PathwayBrowser/#/R-HSA-9021306 C1-Inh binds and inactivates C1r, C1s TAS Homo sapiens A0A0C4DH73 R-HSA-9606151 https://reactome.org/PathwayBrowser/#/R-HSA-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 TAS Homo sapiens A0A0C4DH73 R-HSA-9606159 https://reactome.org/PathwayBrowser/#/R-HSA-9606159 BTK autophosphorylates IEA Homo sapiens A0A0C4DH73 R-HSA-9606162 https://reactome.org/PathwayBrowser/#/R-HSA-9606162 Phosphorylated BTK phosphorylates PLCG2 IEA Homo sapiens A0A0C4DH73 R-HSA-9606163 https://reactome.org/PathwayBrowser/#/R-HSA-9606163 p-SYK and LYN phosphorylate BTK IEA Homo sapiens A0A0C4DH73 R-HSA-9664261 https://reactome.org/PathwayBrowser/#/R-HSA-9664261 Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK TAS Homo sapiens A0A0C4DH73 R-HSA-9664268 https://reactome.org/PathwayBrowser/#/R-HSA-9664268 Opsonized leishmania amastigote binds FCGR3 TAS Homo sapiens A0A0C4DH73 R-HSA-9664270 https://reactome.org/PathwayBrowser/#/R-HSA-9664270 Recruitment of PLCgamma to membrane due to FCGR3A effect TAS Homo sapiens A0A0C4DH73 R-HSA-9664271 https://reactome.org/PathwayBrowser/#/R-HSA-9664271 Release of PLCG from FCGR3A TAS Homo sapiens A0A0C4DH73 R-HSA-9664273 https://reactome.org/PathwayBrowser/#/R-HSA-9664273 SYK binds IgG:Lma antigens:FCGR3A:p-CD3 dimers TAS Homo sapiens A0A0C4DH73 R-HSA-9664275 https://reactome.org/PathwayBrowser/#/R-HSA-9664275 Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers TAS Homo sapiens A0A0C4DH73 R-HSA-9664278 https://reactome.org/PathwayBrowser/#/R-HSA-9664278 Phosphorylation and activation of PLCG due to FCGR3A effect TAS Homo sapiens A0A0C4DH73 R-HSA-9664285 https://reactome.org/PathwayBrowser/#/R-HSA-9664285 IgG binds the surface of the amastigote form of Leishmania TAS Homo sapiens A0A0C4DH73 R-HSA-9664397 https://reactome.org/PathwayBrowser/#/R-HSA-9664397 IgG binds LPG1G2 in the amastigote form of Leishmania IEA Homo sapiens A0A0C4DH73 R-HSA-9664406 https://reactome.org/PathwayBrowser/#/R-HSA-9664406 IgG:Lma antigens binds FCGR3A:CD3 dimers TAS Homo sapiens A0A0C4DH73 R-HSA-9666425 https://reactome.org/PathwayBrowser/#/R-HSA-9666425 p-6Y-SYK phosphorylates VAV1,2,3 TAS Homo sapiens A0A0C4DH73 R-HSA-9666426 https://reactome.org/PathwayBrowser/#/R-HSA-9666426 CRKII:DOCK180:ELMO binds FCGR3A TAS Homo sapiens A0A0C4DH73 R-HSA-9666428 https://reactome.org/PathwayBrowser/#/R-HSA-9666428 DOCK180 exchanges GTP for GDP on RAC1:GDP TAS Homo sapiens A0A0C4DH73 R-HSA-9666430 https://reactome.org/PathwayBrowser/#/R-HSA-9666430 p-VAV1,2,3 exchanges GTP for GDP on RAC1:GDP TAS Homo sapiens A0A0C4DH73 R-HSA-9666433 https://reactome.org/PathwayBrowser/#/R-HSA-9666433 IgG binds the surface of the amastigote form of Leishmania TAS Homo sapiens A0A0C4DH73 R-HSA-9666435 https://reactome.org/PathwayBrowser/#/R-HSA-9666435 VAV1,2,3:PI(3,4,5)P3 binds p-6Y-SYK TAS Homo sapiens A0A0C4DH73 R-HSA-9666458 https://reactome.org/PathwayBrowser/#/R-HSA-9666458 IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole TAS Homo sapiens A0A0C4DH73 R-HSA-9691421 https://reactome.org/PathwayBrowser/#/R-HSA-9691421 BTK binds BTK inhibitors TAS Homo sapiens A0A0C4DH73 R-HSA-9724685 https://reactome.org/PathwayBrowser/#/R-HSA-9724685 IgE binds omalizumab TAS Homo sapiens A0A0C4DH73 R-HSA-9725206 https://reactome.org/PathwayBrowser/#/R-HSA-9725206 IgE binds FCERI TAS Homo sapiens A0A0C4DH73 R-HSA-983696 https://reactome.org/PathwayBrowser/#/R-HSA-983696 The Immunoglobulin of the BCR binds antigen TAS Homo sapiens A0A0C4DH73 R-HSA-983700 https://reactome.org/PathwayBrowser/#/R-HSA-983700 SYK binds the activated BCR TAS Homo sapiens A0A0C4DH73 R-HSA-983703 https://reactome.org/PathwayBrowser/#/R-HSA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) TAS Homo sapiens A0A0C4DH73 R-HSA-983707 https://reactome.org/PathwayBrowser/#/R-HSA-983707 SYK autophosphorylates at the activated BCR TAS Homo sapiens A0A0C4DH73 R-HSA-983709 https://reactome.org/PathwayBrowser/#/R-HSA-983709 LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B) IEA Homo sapiens A0A0C4DHA5 R-DME-6811428 https://reactome.org/PathwayBrowser/#/R-DME-6811428 RIC1:RGP1 recruits RAB6:GDP to the TGN IEA Drosophila melanogaster A0A0C4DHA5 R-DME-6811429 https://reactome.org/PathwayBrowser/#/R-DME-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Drosophila melanogaster A0A0C4DHA5 R-DME-6814682 https://reactome.org/PathwayBrowser/#/R-DME-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Drosophila melanogaster A0A0C4DHA5 R-DME-8876193 https://reactome.org/PathwayBrowser/#/R-DME-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Drosophila melanogaster A0A0C4DHC8 R-DME-389609 https://reactome.org/PathwayBrowser/#/R-DME-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Drosophila melanogaster A0A0C4DHC8 R-DME-5692261 https://reactome.org/PathwayBrowser/#/R-DME-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Drosophila melanogaster A0A0C4DHC8 R-DME-5692283 https://reactome.org/PathwayBrowser/#/R-DME-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Drosophila melanogaster A0A0C4DHC8 R-DME-5696080 https://reactome.org/PathwayBrowser/#/R-DME-5696080 ALDH3B1 oxidises HXAL to PALM IEA Drosophila melanogaster A0A0C4DHC8 R-DME-6798743 https://reactome.org/PathwayBrowser/#/R-DME-6798743 Exocytosis of secretory granule membrane proteins IEA Drosophila melanogaster A0A0C4DHC8 R-DME-6799350 https://reactome.org/PathwayBrowser/#/R-DME-6799350 Exocytosis of specific granule membrane proteins IEA Drosophila melanogaster A0A0C4DHC8 R-DME-6808464 https://reactome.org/PathwayBrowser/#/R-DME-6808464 ALDH3B2 oxidises HXAL to PALM IEA Drosophila melanogaster A0A0C4DHC8 R-DME-9603775 https://reactome.org/PathwayBrowser/#/R-DME-9603775 PEX3:PEX19:class I PMP dissociates IEA Drosophila melanogaster A0A0C4DHC8 R-DME-9603784 https://reactome.org/PathwayBrowser/#/R-DME-9603784 PEX19:class I PMP binds PEX3 IEA Drosophila melanogaster A0A0C4DHC8 R-DME-9603804 https://reactome.org/PathwayBrowser/#/R-DME-9603804 PEX19 binds class I peroxisomal membrane proteins IEA Drosophila melanogaster A0A0C4DHC8 R-DME-9609921 https://reactome.org/PathwayBrowser/#/R-DME-9609921 SGTA binds Tail-anchored protein IEA Drosophila melanogaster A0A0C4DHF6 R-DME-2396395 https://reactome.org/PathwayBrowser/#/R-DME-2396395 HSPG2 (perlecan) binds alpha-dystroglycan IEA Drosophila melanogaster A0A0C4DHF6 R-DME-5615637 https://reactome.org/PathwayBrowser/#/R-DME-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Drosophila melanogaster A0A0C4DHF6 R-DME-9010872 https://reactome.org/PathwayBrowser/#/R-DME-9010872 SLIT2 binds Dystroglycan IEA Drosophila melanogaster A0A0C4DHF6 R-DME-9913329 https://reactome.org/PathwayBrowser/#/R-DME-9913329 Autoproteolysis of DAG1 to alpha and beta chains IEA Drosophila melanogaster A0A0C4DHF6 R-DME-9913332 https://reactome.org/PathwayBrowser/#/R-DME-9913332 DAG1(30-653), DAG1(654-895) and SSPN bind SGC IEA Drosophila melanogaster A0A0C4DHF6 R-DME-9913336 https://reactome.org/PathwayBrowser/#/R-DME-9913336 SGC:DAG1:SSPN complex translocates to plasma membrane IEA Drosophila melanogaster A0A0C4DHF6 R-DME-9913337 https://reactome.org/PathwayBrowser/#/R-DME-9913337 DAG1(30-653) and DAG1(654-895) translocate to the Golgi IEA Drosophila melanogaster A0A0C4DHF9 R-DME-1237042 https://reactome.org/PathwayBrowser/#/R-DME-1237042 AQP1 tetramer transports CO2 from extracellular region to cytosol IEA Drosophila melanogaster A0A0C4DHF9 R-DME-1247649 https://reactome.org/PathwayBrowser/#/R-DME-1247649 AQP1 tetramer transports CO2 from cytosol to extracellular region IEA Drosophila melanogaster A0A0C4DHF9 R-DME-432010 https://reactome.org/PathwayBrowser/#/R-DME-432010 Aquaporin-1 passively transports water into cell IEA Drosophila melanogaster A0A0C4DHF9 R-DME-432054 https://reactome.org/PathwayBrowser/#/R-DME-432054 Aquaporin-1 passively transports water out of cell IEA Drosophila melanogaster A0A0C4DHF9 R-DME-432065 https://reactome.org/PathwayBrowser/#/R-DME-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Drosophila melanogaster A0A0C4DHF9 R-DME-432067 https://reactome.org/PathwayBrowser/#/R-DME-432067 Aquaporin-4 passively transports water out of cell IEA Drosophila melanogaster A0A0C4DHF9 R-DME-432232 https://reactome.org/PathwayBrowser/#/R-DME-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Drosophila melanogaster A0A0C4DHF9 R-DME-432237 https://reactome.org/PathwayBrowser/#/R-DME-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Drosophila melanogaster A0A0C4DHF9 R-DME-507868 https://reactome.org/PathwayBrowser/#/R-DME-507868 Aquaporins passively transport water into cells IEA Drosophila melanogaster A0A0C4DHF9 R-DME-507870 https://reactome.org/PathwayBrowser/#/R-DME-507870 Aquaporins passively transport water out of cells IEA Drosophila melanogaster A0A0D5BWD2 R-SSC-158218 https://reactome.org/PathwayBrowser/#/R-SSC-158218 prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer IEA Sus scrofa A0A0D5BWD2 R-SSC-158251 https://reactome.org/PathwayBrowser/#/R-SSC-158251 prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer IEA Sus scrofa A0A0D5BWD2 R-SSC-158311 https://reactome.org/PathwayBrowser/#/R-SSC-158311 kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin IEA Sus scrofa A0A0D5BWD2 R-SSC-158313 https://reactome.org/PathwayBrowser/#/R-SSC-158313 factor XII -> factor XIIa IEA Sus scrofa A0A0D5BWD2 R-SSC-158354 https://reactome.org/PathwayBrowser/#/R-SSC-158354 kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer IEA Sus scrofa A0A0D5BWD2 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa A0A0D5BWD2 R-SSC-9013110 https://reactome.org/PathwayBrowser/#/R-SSC-9013110 RHOC binds effectors at the plasma membrane IEA Sus scrofa A0A0D9R827 R-NUL-9926485 https://reactome.org/PathwayBrowser/#/R-NUL-9926485 p-S173 MITF-M binds YWHA dimers TAS Chlorocebus sabaeus A0A0D9RHV9 R-NUL-9926485 https://reactome.org/PathwayBrowser/#/R-NUL-9926485 p-S173 MITF-M binds YWHA dimers TAS Chlorocebus sabaeus A0A0D9RNM2 R-NUL-9926485 https://reactome.org/PathwayBrowser/#/R-NUL-9926485 p-S173 MITF-M binds YWHA dimers TAS Chlorocebus sabaeus A0A0D9RP06 R-NUL-9926485 https://reactome.org/PathwayBrowser/#/R-NUL-9926485 p-S173 MITF-M binds YWHA dimers TAS Chlorocebus sabaeus A0A0D9RZW1 R-NUL-9926485 https://reactome.org/PathwayBrowser/#/R-NUL-9926485 p-S173 MITF-M binds YWHA dimers TAS Chlorocebus sabaeus A0A0D9S330 R-NUL-9603625 https://reactome.org/PathwayBrowser/#/R-NUL-9603625 BAX activation is stimulated by Ntrk3(496-641) and Nelfb TAS Chlorocebus sabaeus A0A0E3D804 R-DRE-5696600 https://reactome.org/PathwayBrowser/#/R-DRE-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Danio rerio A0A0E3KLW5 R-SSC-1855165 https://reactome.org/PathwayBrowser/#/R-SSC-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa A0A0E3KLW5 R-SSC-1855198 https://reactome.org/PathwayBrowser/#/R-SSC-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa A0A0E3KLW5 R-SSC-2023971 https://reactome.org/PathwayBrowser/#/R-SSC-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa A0A0E3KLW5 R-SSC-2023973 https://reactome.org/PathwayBrowser/#/R-SSC-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa A0A0E4BA89 R-GGA-8855915 https://reactome.org/PathwayBrowser/#/R-GGA-8855915 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors IEA Gallus gallus A0A0E4G213 R-DRE-165026 https://reactome.org/PathwayBrowser/#/R-DRE-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Danio rerio A0A0E4G213 R-DRE-549241 https://reactome.org/PathwayBrowser/#/R-DRE-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Danio rerio A0A0E4G213 R-DRE-549297 https://reactome.org/PathwayBrowser/#/R-DRE-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Danio rerio A0A0F6TN93 R-CFA-374298 https://reactome.org/PathwayBrowser/#/R-CFA-374298 Opioid receptors bind opioid peptides IEA Canis familiaris A0A0F6TN93 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris A0A0F6TN93 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris A0A0F6TN93 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris A0A0F7C9F3 R-DRE-451377 https://reactome.org/PathwayBrowser/#/R-DRE-451377 Interaction of IQGAP1 with nephrin IEA Danio rerio A0A0F7C9F3 R-DRE-5626469 https://reactome.org/PathwayBrowser/#/R-DRE-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs IEA Danio rerio A0A0F7C9F3 R-DRE-5626507 https://reactome.org/PathwayBrowser/#/R-DRE-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Danio rerio A0A0F7C9F3 R-DRE-5672304 https://reactome.org/PathwayBrowser/#/R-DRE-5672304 IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 IEA Danio rerio A0A0F7C9F3 R-DRE-6798743 https://reactome.org/PathwayBrowser/#/R-DRE-6798743 Exocytosis of secretory granule membrane proteins IEA Danio rerio A0A0F7C9F3 R-DRE-9013009 https://reactome.org/PathwayBrowser/#/R-DRE-9013009 RHOA binds effectors at the plasma membrane IEA Danio rerio A0A0F7C9F3 R-DRE-9014294 https://reactome.org/PathwayBrowser/#/R-DRE-9014294 RAC2 binds effectors at the plasma membrane IEA Danio rerio A0A0F7C9F3 R-DRE-9018746 https://reactome.org/PathwayBrowser/#/R-DRE-9018746 RHOQ binds effectors at the plasma membrane IEA Danio rerio A0A0F7C9F3 R-DRE-9018766 https://reactome.org/PathwayBrowser/#/R-DRE-9018766 RHOU binds effectors at the plasma membrane IEA Danio rerio A0A0F7C9F3 R-DRE-9018794 https://reactome.org/PathwayBrowser/#/R-DRE-9018794 RHOV binds effectors at the plasma membrane IEA Danio rerio A0A0F7EVQ6 R-DRE-5626469 https://reactome.org/PathwayBrowser/#/R-DRE-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs IEA Danio rerio A0A0F7EVQ6 R-DRE-5626507 https://reactome.org/PathwayBrowser/#/R-DRE-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Danio rerio A0A0F7EVQ6 R-DRE-5672304 https://reactome.org/PathwayBrowser/#/R-DRE-5672304 IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 IEA Danio rerio A0A0F7EVQ6 R-DRE-9013009 https://reactome.org/PathwayBrowser/#/R-DRE-9013009 RHOA binds effectors at the plasma membrane IEA Danio rerio A0A0F7EVQ6 R-DRE-9018746 https://reactome.org/PathwayBrowser/#/R-DRE-9018746 RHOQ binds effectors at the plasma membrane IEA Danio rerio A0A0F7RNT6 R-CFA-482772 https://reactome.org/PathwayBrowser/#/R-CFA-482772 Release of platelet cytosolic components IEA Canis familiaris A0A0F7RPV8 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus A0A0F7RPV8 R-BTA-391375 https://reactome.org/PathwayBrowser/#/R-BTA-391375 Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin IEA Bos taurus A0A0F7RPW1 R-CFA-209840 https://reactome.org/PathwayBrowser/#/R-CFA-209840 Two DITs combine to form thyroxine IEA Canis familiaris A0A0F7RPW1 R-CFA-209925 https://reactome.org/PathwayBrowser/#/R-CFA-209925 DIT and MIT combine to form triiodothyronine IEA Canis familiaris A0A0F7RPW1 R-CFA-378952 https://reactome.org/PathwayBrowser/#/R-CFA-378952 Thyrotropin is a heterodimer IEA Canis familiaris A0A0F7RPW1 R-CFA-378975 https://reactome.org/PathwayBrowser/#/R-CFA-378975 Follitropin is a heterodimer IEA Canis familiaris A0A0F7RPW1 R-CFA-391375 https://reactome.org/PathwayBrowser/#/R-CFA-391375 Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin IEA Canis familiaris A0A0F7RPW1 R-CFA-391378 https://reactome.org/PathwayBrowser/#/R-CFA-391378 Follicle-stimulating hormone receptor can bind FSH IEA Canis familiaris A0A0F7RQS3 R-CFA-391375 https://reactome.org/PathwayBrowser/#/R-CFA-391375 Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin IEA Canis familiaris A0A0G2JDU3 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A0G2JDU3 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A0G2JDU3 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A0G2JDU3 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A0G2JDU3 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A0G2JDU3 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A0G2JDU3 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A0G2JDU3 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A0G2JDU3 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A0G2JDU3 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A0G2JDU3 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A0G2JDU3 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A0G2JDU3 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A0G2JDU3 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A0G2JDU3 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A0G2JDU3 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A0G2JDU3 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A0G2JDU3 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A0G2JDU3 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A0G2JDU3 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A0G2JDU3 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A0G2JDU3 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A0G2JDU3 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A0G2JDU3 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A0G2JDU3 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A0G2JDU3 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A0G2JDU3 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A0G2JDU3 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A0G2JDU3 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A0G2JDU3 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A0G2JDU3 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A0G2JDU3 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A0G2JDU3 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A0G2JDU3 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A0G2JDU3 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A0G2JDU3 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A0G2JDU3 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A0G2JDU3 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A0G2JDU3 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A0G2JDU3 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A0G2JDU3 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A0G2JDU3 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A0G2JDU3 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A0G2JDU3 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A0G2JDU3 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A0G2JDU3 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A0G2JDU3 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A0G2JE99 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A0G2JE99 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A0G2JE99 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A0G2JE99 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A0G2JE99 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A0G2JE99 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A0G2JE99 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A0G2JE99 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A0G2JE99 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A0G2JE99 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A0G2JE99 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A0G2JE99 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A0G2JE99 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A0G2JE99 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A0G2JE99 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A0G2JE99 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A0G2JE99 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A0G2JE99 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A0G2JE99 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A0G2JE99 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A0G2JE99 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A0G2JE99 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A0G2JE99 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A0G2JE99 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A0G2JE99 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A0G2JE99 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A0G2JE99 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A0G2JE99 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A0G2JE99 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A0G2JE99 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A0G2JE99 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A0G2JE99 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A0G2JE99 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A0G2JE99 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A0G2JE99 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A0G2JE99 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A0G2JE99 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A0G2JE99 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A0G2JE99 R-MMU-8858498 https://reactome.org/PathwayBrowser/#/R-MMU-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Mus musculus A0A0G2JE99 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A0G2JE99 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A0G2JE99 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A0G2JE99 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A0G2JE99 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A0G2JE99 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A0G2JE99 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A0G2JE99 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A0G2JE99 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A0G2JEM5 R-MMU-975040 https://reactome.org/PathwayBrowser/#/R-MMU-975040 KRAB-ZNF / KAP Interaction IEA Mus musculus A0A0G2JGH6 R-MMU-975040 https://reactome.org/PathwayBrowser/#/R-MMU-975040 KRAB-ZNF / KAP Interaction IEA Mus musculus A0A0G2JSI4 R-RNO-444773 https://reactome.org/PathwayBrowser/#/R-RNO-444773 EGF-TM7 receptors bind chondroitin sulphate IEA Rattus norvegicus A0A0G2JSI4 R-RNO-6798743 https://reactome.org/PathwayBrowser/#/R-RNO-6798743 Exocytosis of secretory granule membrane proteins IEA Rattus norvegicus A0A0G2JSI4 R-RNO-879674 https://reactome.org/PathwayBrowser/#/R-RNO-879674 CD97 binds CD55 IEA Rattus norvegicus A0A0G2JSL0 R-RNO-1168640 https://reactome.org/PathwayBrowser/#/R-RNO-1168640 Ubiquitinated IkB is degraded IEA Rattus norvegicus A0A0G2JSL0 R-RNO-1234159 https://reactome.org/PathwayBrowser/#/R-RNO-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Rattus norvegicus A0A0G2JSL0 R-RNO-1236970 https://reactome.org/PathwayBrowser/#/R-RNO-1236970 Proteasomal clevage of exogenous antigen (26S proteasome catalyst) IEA Rattus norvegicus A0A0G2JSL0 R-RNO-1504193 https://reactome.org/PathwayBrowser/#/R-RNO-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-174058 https://reactome.org/PathwayBrowser/#/R-RNO-174058 Degradation of multiubiquitinated Cdh1 IEA Rattus norvegicus A0A0G2JSL0 R-RNO-174105 https://reactome.org/PathwayBrowser/#/R-RNO-174105 Degradation of multiubiquitinated cell cycle proteins IEA Rattus norvegicus A0A0G2JSL0 R-RNO-174202 https://reactome.org/PathwayBrowser/#/R-RNO-174202 Degradation of multiubiquitinated Securin IEA Rattus norvegicus A0A0G2JSL0 R-RNO-174203 https://reactome.org/PathwayBrowser/#/R-RNO-174203 SCF-mediated degradation of Emi1 IEA Rattus norvegicus A0A0G2JSL0 R-RNO-174255 https://reactome.org/PathwayBrowser/#/R-RNO-174255 Degradation multiubiquitinated Cyclin A IEA Rattus norvegicus A0A0G2JSL0 R-RNO-187574 https://reactome.org/PathwayBrowser/#/R-RNO-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-188191 https://reactome.org/PathwayBrowser/#/R-RNO-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Rattus norvegicus A0A0G2JSL0 R-RNO-2130282 https://reactome.org/PathwayBrowser/#/R-RNO-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-264458 https://reactome.org/PathwayBrowser/#/R-RNO-264458 Proteasome mediated degradation of COP1 IEA Rattus norvegicus A0A0G2JSL0 R-RNO-353125 https://reactome.org/PathwayBrowser/#/R-RNO-353125 26S proteosome degrades ODC holoenzyme complex IEA Rattus norvegicus A0A0G2JSL0 R-RNO-3640874 https://reactome.org/PathwayBrowser/#/R-RNO-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-450466 https://reactome.org/PathwayBrowser/#/R-RNO-450466 AUF1:mRNA complex is destroyed IEA Rattus norvegicus A0A0G2JSL0 R-RNO-4608855 https://reactome.org/PathwayBrowser/#/R-RNO-4608855 PRICKLE1 is degraded by the proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-4641256 https://reactome.org/PathwayBrowser/#/R-RNO-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-4641260 https://reactome.org/PathwayBrowser/#/R-RNO-4641260 Ubiquitinated DVL1 is degraded by the proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-5362448 https://reactome.org/PathwayBrowser/#/R-RNO-5362448 Hh C-terminal fragments are degraded by the proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-5607731 https://reactome.org/PathwayBrowser/#/R-RNO-5607731 26S proteasome processes p-7S-p100:RELB to form p52:RELB IEA Rattus norvegicus A0A0G2JSL0 R-RNO-5610754 https://reactome.org/PathwayBrowser/#/R-RNO-5610754 GLI3 is partially degraded by the proteasome to yield the GLI3 repressor IEA Rattus norvegicus A0A0G2JSL0 R-RNO-5610758 https://reactome.org/PathwayBrowser/#/R-RNO-5610758 GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP IEA Rattus norvegicus A0A0G2JSL0 R-RNO-5610760 https://reactome.org/PathwayBrowser/#/R-RNO-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Rattus norvegicus A0A0G2JSL0 R-RNO-5635854 https://reactome.org/PathwayBrowser/#/R-RNO-5635854 GLI2,3 are degraded by the proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-5635868 https://reactome.org/PathwayBrowser/#/R-RNO-5635868 ub-GLI is degraded by the proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-5658430 https://reactome.org/PathwayBrowser/#/R-RNO-5658430 NF1 is degraded by the proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-5665854 https://reactome.org/PathwayBrowser/#/R-RNO-5665854 ADRM1:26S proteaseome binds UCHL5 IEA Rattus norvegicus A0A0G2JSL0 R-RNO-5665871 https://reactome.org/PathwayBrowser/#/R-RNO-5665871 ADRM1 binds 26S proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-5668481 https://reactome.org/PathwayBrowser/#/R-RNO-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Rattus norvegicus A0A0G2JSL0 R-RNO-5668520 https://reactome.org/PathwayBrowser/#/R-RNO-5668520 26Sproteasome degrades K48polyUb-NIK IEA Rattus norvegicus A0A0G2JSL0 R-RNO-5687112 https://reactome.org/PathwayBrowser/#/R-RNO-5687112 MAPK6 is degraded by the 26S proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-5689539 https://reactome.org/PathwayBrowser/#/R-RNO-5689539 ADRM1:26S proteaseome binds USP14 IEA Rattus norvegicus A0A0G2JSL0 R-RNO-68825 https://reactome.org/PathwayBrowser/#/R-RNO-68825 Ubiquitinated geminin is degraded by the proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-68948 https://reactome.org/PathwayBrowser/#/R-RNO-68948 Ubiquitinated Orc1 is degraded by the proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-69016 https://reactome.org/PathwayBrowser/#/R-RNO-69016 Ubiquitinated Cdc6 is degraded by the proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-69600 https://reactome.org/PathwayBrowser/#/R-RNO-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Rattus norvegicus A0A0G2JSL0 R-RNO-75825 https://reactome.org/PathwayBrowser/#/R-RNO-75825 Proteasome mediated degradation of Cyclin D1 IEA Rattus norvegicus A0A0G2JSL0 R-RNO-8850992 https://reactome.org/PathwayBrowser/#/R-RNO-8850992 Proteasome degrades polyubiquitinated PTEN IEA Rattus norvegicus A0A0G2JSL0 R-RNO-8852354 https://reactome.org/PathwayBrowser/#/R-RNO-8852354 GTSE1 facilitates proteasome-mediated degradation of TP53 IEA Rattus norvegicus A0A0G2JSL0 R-RNO-8854044 https://reactome.org/PathwayBrowser/#/R-RNO-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Rattus norvegicus A0A0G2JSL0 R-RNO-8854071 https://reactome.org/PathwayBrowser/#/R-RNO-8854071 Proteasome-mediated degradation of PolyUb-FBXL7 IEA Rattus norvegicus A0A0G2JSL0 R-RNO-8866553 https://reactome.org/PathwayBrowser/#/R-RNO-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-8932355 https://reactome.org/PathwayBrowser/#/R-RNO-8932355 26S proteasome degrades Ub-NFE2L2 IEA Rattus norvegicus A0A0G2JSL0 R-RNO-8952408 https://reactome.org/PathwayBrowser/#/R-RNO-8952408 Polyubiquitinated RUNX3 is degraded by the proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-8956140 https://reactome.org/PathwayBrowser/#/R-RNO-8956140 NEDD8 and UBD bind NUB1 and the 26S proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-8956184 https://reactome.org/PathwayBrowser/#/R-RNO-8956184 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates IEA Rattus norvegicus A0A0G2JSL0 R-RNO-8957265 https://reactome.org/PathwayBrowser/#/R-RNO-8957265 26S proteasome degrades TP73 polyubiquitinated by ITCH IEA Rattus norvegicus A0A0G2JSL0 R-RNO-9755303 https://reactome.org/PathwayBrowser/#/R-RNO-9755303 26S proteasome degrades HIFalpha IEA Rattus norvegicus A0A0G2JSL0 R-RNO-9755306 https://reactome.org/PathwayBrowser/#/R-RNO-9755306 ub UBXN7 is degraded by the 26S proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-9762096 https://reactome.org/PathwayBrowser/#/R-RNO-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Rattus norvegicus A0A0G2JSL0 R-RNO-983150 https://reactome.org/PathwayBrowser/#/R-RNO-983150 Proteasomal cleavage of substrate IEA Rattus norvegicus A0A0G2JSL0 R-RNO-9907898 https://reactome.org/PathwayBrowser/#/R-RNO-9907898 Formation of the inner ring of the 20S core particle of the 26S proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-9907919 https://reactome.org/PathwayBrowser/#/R-RNO-9907919 Formation of the preholoproteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-9907925 https://reactome.org/PathwayBrowser/#/R-RNO-9907925 Formation of the inner ring of the 20S immunoproteasome core particle IEA Rattus norvegicus A0A0G2JSL0 R-RNO-9907940 https://reactome.org/PathwayBrowser/#/R-RNO-9907940 Formation of the preholothymoproteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-9907941 https://reactome.org/PathwayBrowser/#/R-RNO-9907941 Fromation of the preholoimmunoproteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-9908101 https://reactome.org/PathwayBrowser/#/R-RNO-9908101 Maturation of the canonical 20S core particle IEA Rattus norvegicus A0A0G2JSL0 R-RNO-9908709 https://reactome.org/PathwayBrowser/#/R-RNO-9908709 Formation of the PA28-alpha-beta-20S proteasome IEA Rattus norvegicus A0A0G2JSL0 R-RNO-9912636 https://reactome.org/PathwayBrowser/#/R-RNO-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Rattus norvegicus A0A0G2JSL0 R-RNO-9912655 https://reactome.org/PathwayBrowser/#/R-RNO-9912655 Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) IEA Rattus norvegicus A0A0G2JSL0 R-RNO-9912747 https://reactome.org/PathwayBrowser/#/R-RNO-9912747 Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) IEA Rattus norvegicus A0A0G2JSL0 R-RNO-9912751 https://reactome.org/PathwayBrowser/#/R-RNO-9912751 Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) IEA Rattus norvegicus A0A0G2JSL0 R-RNO-9934893 https://reactome.org/PathwayBrowser/#/R-RNO-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 IEA Rattus norvegicus A0A0G2JSN6 R-RNO-6799350 https://reactome.org/PathwayBrowser/#/R-RNO-6799350 Exocytosis of specific granule membrane proteins IEA Rattus norvegicus A0A0G2JST1 R-RNO-9614271 https://reactome.org/PathwayBrowser/#/R-RNO-9614271 Autocleavage of ADGRG6 IEA Rattus norvegicus A0A0G2JST1 R-RNO-9614273 https://reactome.org/PathwayBrowser/#/R-RNO-9614273 ADGRG heterodimer translocates to plasma membrane IEA Rattus norvegicus A0A0G2JSV3 R-RNO-73580 https://reactome.org/PathwayBrowser/#/R-RNO-73580 PRPS dimers pyrophosphorylate R5P using ATP IEA Rattus norvegicus A0A0G2JT44 R-RNO-6798747 https://reactome.org/PathwayBrowser/#/R-RNO-6798747 Exocytosis of tertiary granule membrane proteins IEA Rattus norvegicus A0A0G2JT44 R-RNO-6799350 https://reactome.org/PathwayBrowser/#/R-RNO-6799350 Exocytosis of specific granule membrane proteins IEA Rattus norvegicus A0A0G2JT78 R-RNO-6811428 https://reactome.org/PathwayBrowser/#/R-RNO-6811428 RIC1:RGP1 recruits RAB6:GDP to the TGN IEA Rattus norvegicus A0A0G2JT78 R-RNO-6811429 https://reactome.org/PathwayBrowser/#/R-RNO-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Rattus norvegicus A0A0G2JT78 R-RNO-6811431 https://reactome.org/PathwayBrowser/#/R-RNO-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Rattus norvegicus A0A0G2JT78 R-RNO-6814682 https://reactome.org/PathwayBrowser/#/R-RNO-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Rattus norvegicus A0A0G2JT78 R-RNO-8849348 https://reactome.org/PathwayBrowser/#/R-RNO-8849348 RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo IEA Rattus norvegicus A0A0G2JT78 R-RNO-8849350 https://reactome.org/PathwayBrowser/#/R-RNO-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Rattus norvegicus A0A0G2JT78 R-RNO-8849353 https://reactome.org/PathwayBrowser/#/R-RNO-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Rattus norvegicus A0A0G2JT78 R-RNO-8854303 https://reactome.org/PathwayBrowser/#/R-RNO-8854303 TBC1D11 binds RAB6 IEA Rattus norvegicus A0A0G2JT78 R-RNO-8870466 https://reactome.org/PathwayBrowser/#/R-RNO-8870466 RGGT:CHM binds RABs IEA Rattus norvegicus A0A0G2JT78 R-RNO-8870469 https://reactome.org/PathwayBrowser/#/R-RNO-8870469 RGGT geranylgeranylates RAB proteins IEA Rattus norvegicus A0A0G2JT78 R-RNO-8876193 https://reactome.org/PathwayBrowser/#/R-RNO-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Rattus norvegicus A0A0G2JTB0 R-RNO-3640844 https://reactome.org/PathwayBrowser/#/R-RNO-3640844 RNF146 binds RibC-AXIN:TNKS complex IEA Rattus norvegicus A0A0G2JTB0 R-RNO-3640858 https://reactome.org/PathwayBrowser/#/R-RNO-3640858 Tankyrase ADP-ribosylates AXIN IEA Rattus norvegicus A0A0G2JTB0 R-RNO-3640861 https://reactome.org/PathwayBrowser/#/R-RNO-3640861 RNF146 ubiquitinates ADP-ribosylated AXIN IEA Rattus norvegicus A0A0G2JTB0 R-RNO-3640862 https://reactome.org/PathwayBrowser/#/R-RNO-3640862 Tankyrase binds AXIN IEA Rattus norvegicus A0A0G2JTB0 R-RNO-3640872 https://reactome.org/PathwayBrowser/#/R-RNO-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Rattus norvegicus A0A0G2JTB0 R-RNO-3640874 https://reactome.org/PathwayBrowser/#/R-RNO-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Rattus norvegicus A0A0G2JTB0 R-RNO-8948800 https://reactome.org/PathwayBrowser/#/R-RNO-8948800 TNKS and TNKS2 PARylate PTEN IEA Rattus norvegicus A0A0G2JTB2 R-RNO-3322005 https://reactome.org/PathwayBrowser/#/R-RNO-3322005 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a IEA Rattus norvegicus A0A0G2JTB2 R-RNO-3322057 https://reactome.org/PathwayBrowser/#/R-RNO-3322057 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b IEA Rattus norvegicus A0A0G2JTB3 R-RNO-9934021 https://reactome.org/PathwayBrowser/#/R-RNO-9934021 Formation of neuronal progenitor BAF (npBAF) IEA Rattus norvegicus A0A0G2JTB3 R-RNO-9934024 https://reactome.org/PathwayBrowser/#/R-RNO-9934024 SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10 IEA Rattus norvegicus A0A0G2JTC9 R-RNO-5691108 https://reactome.org/PathwayBrowser/#/R-RNO-5691108 SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 IEA Rattus norvegicus A0A0G2JTC9 R-RNO-5691167 https://reactome.org/PathwayBrowser/#/R-RNO-5691167 CUL1, SKP1, FBXL5 bind IEA Rattus norvegicus A0A0G2JTC9 R-RNO-5691176 https://reactome.org/PathwayBrowser/#/R-RNO-5691176 NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) IEA Rattus norvegicus A0A0G2JTC9 R-RNO-8952618 https://reactome.org/PathwayBrowser/#/R-RNO-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JTC9 R-RNO-8952620 https://reactome.org/PathwayBrowser/#/R-RNO-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JTC9 R-RNO-8955241 https://reactome.org/PathwayBrowser/#/R-RNO-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Rattus norvegicus A0A0G2JTC9 R-RNO-8955289 https://reactome.org/PathwayBrowser/#/R-RNO-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Rattus norvegicus A0A0G2JTC9 R-RNO-8956040 https://reactome.org/PathwayBrowser/#/R-RNO-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Rattus norvegicus A0A0G2JTC9 R-RNO-8956200 https://reactome.org/PathwayBrowser/#/R-RNO-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JTC9 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2JTC9 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus A0A0G2JTC9 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2JTC9 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2JTI7 R-RNO-9770142 https://reactome.org/PathwayBrowser/#/R-RNO-9770142 Formation of the Spliceosomal B complex IEA Rattus norvegicus A0A0G2JTI9 R-RNO-168915 https://reactome.org/PathwayBrowser/#/R-RNO-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5357757 https://reactome.org/PathwayBrowser/#/R-RNO-5357757 BIRC(cIAP1/2) ubiquitinates RIPK1 IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5357776 https://reactome.org/PathwayBrowser/#/R-RNO-5357776 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5357780 https://reactome.org/PathwayBrowser/#/R-RNO-5357780 TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5357845 https://reactome.org/PathwayBrowser/#/R-RNO-5357845 K63polyUb-RIPK1 is deubiquitinated IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5357860 https://reactome.org/PathwayBrowser/#/R-RNO-5357860 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5668414 https://reactome.org/PathwayBrowser/#/R-RNO-5668414 TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5668417 https://reactome.org/PathwayBrowser/#/R-RNO-5668417 cIAP1,2:TRAF2:TRAF3:NIK complex binds TNFR2 trimer IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5668454 https://reactome.org/PathwayBrowser/#/R-RNO-5668454 K63polyUb-cIAP1,2 ubiquitinates TRAF3 IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5668481 https://reactome.org/PathwayBrowser/#/R-RNO-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5668534 https://reactome.org/PathwayBrowser/#/R-RNO-5668534 cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5668543 https://reactome.org/PathwayBrowser/#/R-RNO-5668543 TRAF3:NIK binds TRAF2:cIAP1/2 IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5675470 https://reactome.org/PathwayBrowser/#/R-RNO-5675470 BIRC2/3 (cIAP1/2) is autoubiquitinated IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5676593 https://reactome.org/PathwayBrowser/#/R-RNO-5676593 TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5676595 https://reactome.org/PathwayBrowser/#/R-RNO-5676595 TRAFs bind RANK:RANKL IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5676596 https://reactome.org/PathwayBrowser/#/R-RNO-5676596 TRAF3 binds BAFFR:BAFF IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5676597 https://reactome.org/PathwayBrowser/#/R-RNO-5676597 TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5676598 https://reactome.org/PathwayBrowser/#/R-RNO-5676598 TRAF2:cIAP1/2 complex binds FN14:TWEAK IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5693055 https://reactome.org/PathwayBrowser/#/R-RNO-5693055 TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes IEA Rattus norvegicus A0A0G2JTI9 R-RNO-5693108 https://reactome.org/PathwayBrowser/#/R-RNO-5693108 TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains IEA Rattus norvegicus A0A0G2JTI9 R-RNO-6781797 https://reactome.org/PathwayBrowser/#/R-RNO-6781797 USP19 binds HIF1A,BIRC2,BIRC3 IEA Rattus norvegicus A0A0G2JTI9 R-RNO-688137 https://reactome.org/PathwayBrowser/#/R-RNO-688137 RIP2 is K63 polyubiquitinated IEA Rattus norvegicus A0A0G2JTI9 R-RNO-83582 https://reactome.org/PathwayBrowser/#/R-RNO-83582 TRADD:TRAF2:RIP1 dissociates from TNF-α:TNFR1 IEA Rattus norvegicus A0A0G2JTI9 R-RNO-9793679 https://reactome.org/PathwayBrowser/#/R-RNO-9793679 LUBAC ubiquitinates RIPK1 at K627 IEA Rattus norvegicus A0A0G2JTI9 R-RNO-9793680 https://reactome.org/PathwayBrowser/#/R-RNO-9793680 OPTN binds polyUb-RIPK1 within the TNFR1 complex IEA Rattus norvegicus A0A0G2JTI9 R-RNO-9796379 https://reactome.org/PathwayBrowser/#/R-RNO-9796379 CYLD:SPATA2:LUBAC binds TNFR1 signaling complex IEA Rattus norvegicus A0A0G2JTI9 R-RNO-9817362 https://reactome.org/PathwayBrowser/#/R-RNO-9817362 SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex IEA Rattus norvegicus A0A0G2JTI9 R-RNO-9817397 https://reactome.org/PathwayBrowser/#/R-RNO-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Rattus norvegicus A0A0G2JTI9 R-RNO-9817400 https://reactome.org/PathwayBrowser/#/R-RNO-9817400 CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex IEA Rattus norvegicus A0A0G2JTI9 R-RNO-9817411 https://reactome.org/PathwayBrowser/#/R-RNO-9817411 TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex IEA Rattus norvegicus A0A0G2JTI9 R-RNO-9818789 https://reactome.org/PathwayBrowser/#/R-RNO-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 IEA Rattus norvegicus A0A0G2JTI9 R-RNO-9818975 https://reactome.org/PathwayBrowser/#/R-RNO-9818975 CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex IEA Rattus norvegicus A0A0G2JTI9 R-RNO-9824874 https://reactome.org/PathwayBrowser/#/R-RNO-9824874 OPTN recruits CYLD to the TNFR1 complex IEA Rattus norvegicus A0A0G2JTM6 R-RNO-9770141 https://reactome.org/PathwayBrowser/#/R-RNO-9770141 Formation of the Spliceosomal C* complex IEA Rattus norvegicus A0A0G2JTM6 R-RNO-9794542 https://reactome.org/PathwayBrowser/#/R-RNO-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Rattus norvegicus A0A0G2JTM7 R-RNO-3222093 https://reactome.org/PathwayBrowser/#/R-RNO-3222093 BRD7 binds TP53 and EP300 IEA Rattus norvegicus A0A0G2JTM7 R-RNO-5628871 https://reactome.org/PathwayBrowser/#/R-RNO-5628871 BRD7 promotes EP300-mediated acetylation of TP53 IEA Rattus norvegicus A0A0G2JTM7 R-RNO-6805650 https://reactome.org/PathwayBrowser/#/R-RNO-6805650 MTA2-NuRD complex deacetylates TP53 IEA Rattus norvegicus A0A0G2JTM7 R-RNO-9932832 https://reactome.org/PathwayBrowser/#/R-RNO-9932832 BRD7 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2 IEA Rattus norvegicus A0A0G2JTM7 R-RNO-9932843 https://reactome.org/PathwayBrowser/#/R-RNO-9932843 PHF10 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD7 IEA Rattus norvegicus A0A0G2JTM7 R-RNO-9933237 https://reactome.org/PathwayBrowser/#/R-RNO-9933237 PBRM1-containing ATPase complex binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD&:PHF10 IEA Rattus norvegicus A0A0G2JTQ9 R-RNO-211881 https://reactome.org/PathwayBrowser/#/R-RNO-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Rattus norvegicus A0A0G2JTQ9 R-RNO-211966 https://reactome.org/PathwayBrowser/#/R-RNO-211966 CYP2D6 4-hydroxylates debrisoquine IEA Rattus norvegicus A0A0G2JTQ9 R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus A0A0G2JTQ9 R-RNO-211991 https://reactome.org/PathwayBrowser/#/R-RNO-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Rattus norvegicus A0A0G2JTQ9 R-RNO-212005 https://reactome.org/PathwayBrowser/#/R-RNO-212005 CYP2F1 dehydrogenates 3-methylindole IEA Rattus norvegicus A0A0G2JTQ9 R-RNO-2161890 https://reactome.org/PathwayBrowser/#/R-RNO-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Rattus norvegicus A0A0G2JTQ9 R-RNO-2161899 https://reactome.org/PathwayBrowser/#/R-RNO-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Rattus norvegicus A0A0G2JTQ9 R-RNO-76456 https://reactome.org/PathwayBrowser/#/R-RNO-76456 O-atom dealkylation of dextromethorphan IEA Rattus norvegicus A0A0G2JTQ9 R-RNO-9915971 https://reactome.org/PathwayBrowser/#/R-RNO-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Rattus norvegicus A0A0G2JTQ9 R-RNO-9915997 https://reactome.org/PathwayBrowser/#/R-RNO-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Rattus norvegicus A0A0G2JTR3 R-RNO-5617816 https://reactome.org/PathwayBrowser/#/R-RNO-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Rattus norvegicus A0A0G2JTR3 R-RNO-5626681 https://reactome.org/PathwayBrowser/#/R-RNO-5626681 Recruitment of transition zone proteins IEA Rattus norvegicus A0A0G2JTR3 R-RNO-5638009 https://reactome.org/PathwayBrowser/#/R-RNO-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Rattus norvegicus A0A0G2JTR4 R-RNO-205039 https://reactome.org/PathwayBrowser/#/R-RNO-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Rattus norvegicus A0A0G2JTR4 R-RNO-419166 https://reactome.org/PathwayBrowser/#/R-RNO-419166 GEFs activate RhoA,B,C IEA Rattus norvegicus A0A0G2JTR4 R-RNO-8980691 https://reactome.org/PathwayBrowser/#/R-RNO-8980691 RHOA GEFs activate RHOA IEA Rattus norvegicus A0A0G2JTR4 R-RNO-8981637 https://reactome.org/PathwayBrowser/#/R-RNO-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Rattus norvegicus A0A0G2JTR4 R-RNO-9013022 https://reactome.org/PathwayBrowser/#/R-RNO-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Rattus norvegicus A0A0G2JTR4 R-RNO-9013143 https://reactome.org/PathwayBrowser/#/R-RNO-9013143 RAC1 GEFs activate RAC1 IEA Rattus norvegicus A0A0G2JTR4 R-RNO-9013144 https://reactome.org/PathwayBrowser/#/R-RNO-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Rattus norvegicus A0A0G2JTR4 R-RNO-9013159 https://reactome.org/PathwayBrowser/#/R-RNO-9013159 CDC42 GEFs activate CDC42 IEA Rattus norvegicus A0A0G2JTR4 R-RNO-9013161 https://reactome.org/PathwayBrowser/#/R-RNO-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Rattus norvegicus A0A0G2JTR4 R-RNO-9014295 https://reactome.org/PathwayBrowser/#/R-RNO-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Rattus norvegicus A0A0G2JTR4 R-RNO-9014296 https://reactome.org/PathwayBrowser/#/R-RNO-9014296 RAC2 GEFs activate RAC2 IEA Rattus norvegicus A0A0G2JTT4 R-RNO-8849748 https://reactome.org/PathwayBrowser/#/R-RNO-8849748 The COG complex binds RABs at the Golgi membrane IEA Rattus norvegicus A0A0G2JTT4 R-RNO-8870466 https://reactome.org/PathwayBrowser/#/R-RNO-8870466 RGGT:CHM binds RABs IEA Rattus norvegicus A0A0G2JTT4 R-RNO-8870469 https://reactome.org/PathwayBrowser/#/R-RNO-8870469 RGGT geranylgeranylates RAB proteins IEA Rattus norvegicus A0A0G2JTT6 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2JTT6 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus A0A0G2JTT6 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2JTT6 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2JTU0 R-RNO-205039 https://reactome.org/PathwayBrowser/#/R-RNO-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Rattus norvegicus A0A0G2JTU0 R-RNO-419166 https://reactome.org/PathwayBrowser/#/R-RNO-419166 GEFs activate RhoA,B,C IEA Rattus norvegicus A0A0G2JTU0 R-RNO-8980691 https://reactome.org/PathwayBrowser/#/R-RNO-8980691 RHOA GEFs activate RHOA IEA Rattus norvegicus A0A0G2JTU0 R-RNO-9013143 https://reactome.org/PathwayBrowser/#/R-RNO-9013143 RAC1 GEFs activate RAC1 IEA Rattus norvegicus A0A0G2JTU0 R-RNO-9013159 https://reactome.org/PathwayBrowser/#/R-RNO-9013159 CDC42 GEFs activate CDC42 IEA Rattus norvegicus A0A0G2JTU1 R-RNO-5250930 https://reactome.org/PathwayBrowser/#/R-RNO-5250930 B-WICH recruits histone acetyltransferases IEA Rattus norvegicus A0A0G2JTU1 R-RNO-5250938 https://reactome.org/PathwayBrowser/#/R-RNO-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Rattus norvegicus A0A0G2JTU1 R-RNO-5250947 https://reactome.org/PathwayBrowser/#/R-RNO-5250947 B-WICH complex binds rDNA promoter IEA Rattus norvegicus A0A0G2JTU1 R-RNO-6781833 https://reactome.org/PathwayBrowser/#/R-RNO-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Rattus norvegicus A0A0G2JTU1 R-RNO-6781840 https://reactome.org/PathwayBrowser/#/R-RNO-6781840 ERCC6 binds stalled RNA Pol II IEA Rattus norvegicus A0A0G2JTU1 R-RNO-6781867 https://reactome.org/PathwayBrowser/#/R-RNO-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Rattus norvegicus A0A0G2JTU1 R-RNO-6782004 https://reactome.org/PathwayBrowser/#/R-RNO-6782004 Assembly of the pre-incision complex in TC-NER IEA Rattus norvegicus A0A0G2JTU1 R-RNO-6782069 https://reactome.org/PathwayBrowser/#/R-RNO-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Rattus norvegicus A0A0G2JTU1 R-RNO-6782131 https://reactome.org/PathwayBrowser/#/R-RNO-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Rattus norvegicus A0A0G2JTU1 R-RNO-6782138 https://reactome.org/PathwayBrowser/#/R-RNO-6782138 ERCC5 and RPA bind TC-NER site IEA Rattus norvegicus A0A0G2JTU1 R-RNO-6782141 https://reactome.org/PathwayBrowser/#/R-RNO-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Rattus norvegicus A0A0G2JTU1 R-RNO-6782204 https://reactome.org/PathwayBrowser/#/R-RNO-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Rattus norvegicus A0A0G2JTU1 R-RNO-6782208 https://reactome.org/PathwayBrowser/#/R-RNO-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Rattus norvegicus A0A0G2JTU1 R-RNO-6782211 https://reactome.org/PathwayBrowser/#/R-RNO-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Rattus norvegicus A0A0G2JTU1 R-RNO-6782224 https://reactome.org/PathwayBrowser/#/R-RNO-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Rattus norvegicus A0A0G2JTU1 R-RNO-6782227 https://reactome.org/PathwayBrowser/#/R-RNO-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Rattus norvegicus A0A0G2JTU1 R-RNO-73739 https://reactome.org/PathwayBrowser/#/R-RNO-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter IEA Rattus norvegicus A0A0G2JTU1 R-RNO-9684118 https://reactome.org/PathwayBrowser/#/R-RNO-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Rattus norvegicus A0A0G2JTV0 R-RNO-2454192 https://reactome.org/PathwayBrowser/#/R-RNO-2454192 Allergen dependent IgE bound FCERI aggregation IEA Rattus norvegicus A0A0G2JTV0 R-RNO-2454208 https://reactome.org/PathwayBrowser/#/R-RNO-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Rattus norvegicus A0A0G2JTV0 R-RNO-2454240 https://reactome.org/PathwayBrowser/#/R-RNO-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Rattus norvegicus A0A0G2JTV0 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus A0A0G2JTV0 R-RNO-2730843 https://reactome.org/PathwayBrowser/#/R-RNO-2730843 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus A0A0G2JTV0 R-RNO-2730851 https://reactome.org/PathwayBrowser/#/R-RNO-2730851 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus A0A0G2JTV0 R-RNO-2730882 https://reactome.org/PathwayBrowser/#/R-RNO-2730882 Phosphorylation of PKC-theta IEA Rattus norvegicus A0A0G2JTV0 R-RNO-2730884 https://reactome.org/PathwayBrowser/#/R-RNO-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Rattus norvegicus A0A0G2JTV0 R-RNO-2730886 https://reactome.org/PathwayBrowser/#/R-RNO-2730886 Phosphorylation of SHC by SYK kinase IEA Rattus norvegicus A0A0G2JTV0 R-RNO-9724685 https://reactome.org/PathwayBrowser/#/R-RNO-9724685 IgE binds omalizumab IEA Rattus norvegicus A0A0G2JTV0 R-RNO-9725206 https://reactome.org/PathwayBrowser/#/R-RNO-9725206 IgE binds FCERI IEA Rattus norvegicus A0A0G2JTX7 R-RNO-1650808 https://reactome.org/PathwayBrowser/#/R-RNO-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Rattus norvegicus A0A0G2JTX7 R-RNO-1980233 https://reactome.org/PathwayBrowser/#/R-RNO-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Rattus norvegicus A0A0G2JTX7 R-RNO-1981104 https://reactome.org/PathwayBrowser/#/R-RNO-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Rattus norvegicus A0A0G2JTX7 R-RNO-1981120 https://reactome.org/PathwayBrowser/#/R-RNO-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Rattus norvegicus A0A0G2JTX7 R-RNO-1981128 https://reactome.org/PathwayBrowser/#/R-RNO-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Rattus norvegicus A0A0G2JTX7 R-RNO-1981157 https://reactome.org/PathwayBrowser/#/R-RNO-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Rattus norvegicus A0A0G2JTX7 R-RNO-2002460 https://reactome.org/PathwayBrowser/#/R-RNO-2002460 P4HB binds Collagen chains IEA Rattus norvegicus A0A0G2JTX7 R-RNO-8948219 https://reactome.org/PathwayBrowser/#/R-RNO-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus A0A0G2JTX7 R-RNO-8948222 https://reactome.org/PathwayBrowser/#/R-RNO-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2JTX7 R-RNO-8948224 https://reactome.org/PathwayBrowser/#/R-RNO-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2JTX7 R-RNO-8948228 https://reactome.org/PathwayBrowser/#/R-RNO-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus A0A0G2JTX7 R-RNO-8948231 https://reactome.org/PathwayBrowser/#/R-RNO-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2JTX7 R-RNO-8948232 https://reactome.org/PathwayBrowser/#/R-RNO-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Rattus norvegicus A0A0G2JTX7 R-RNO-8948234 https://reactome.org/PathwayBrowser/#/R-RNO-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Rattus norvegicus A0A0G2JTY3 R-RNO-198513 https://reactome.org/PathwayBrowser/#/R-RNO-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Rattus norvegicus A0A0G2JTY4 R-RNO-2025890 https://reactome.org/PathwayBrowser/#/R-RNO-2025890 Calcineurin binds NFATC1,2,3 IEA Rattus norvegicus A0A0G2JTY4 R-RNO-2730849 https://reactome.org/PathwayBrowser/#/R-RNO-2730849 Calcineurin binds and dephosphorylates NFAT IEA Rattus norvegicus A0A0G2JTY4 R-RNO-2730867 https://reactome.org/PathwayBrowser/#/R-RNO-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Rattus norvegicus A0A0G2JTZ2 R-RNO-5626938 https://reactome.org/PathwayBrowser/#/R-RNO-5626938 Beta-catenin binds SOX proteins IEA Rattus norvegicus A0A0G2JU02 R-RNO-2022052 https://reactome.org/PathwayBrowser/#/R-RNO-2022052 Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS) IEA Rattus norvegicus A0A0G2JU09 R-RNO-4647593 https://reactome.org/PathwayBrowser/#/R-RNO-4647593 EP400 binds CDKN1A promoter IEA Rattus norvegicus A0A0G2JU13 R-RNO-8862090 https://reactome.org/PathwayBrowser/#/R-RNO-8862090 PILRA binds PIANP, COLLEC12 trimer, NPDC1, CLEC4G IEA Rattus norvegicus A0A0G2JU37 R-RNO-6809663 https://reactome.org/PathwayBrowser/#/R-RNO-6809663 Formation of hair keratin fibres IEA Rattus norvegicus A0A0G2JU49 R-RNO-9714477 https://reactome.org/PathwayBrowser/#/R-RNO-9714477 RAC2 binds effectors at the mitochondrial outer membrane IEA Rattus norvegicus A0A0G2JU68 R-RNO-381518 https://reactome.org/PathwayBrowser/#/R-RNO-381518 PAAP-A proteolyzes IGF:IGFBP4 IEA Rattus norvegicus A0A0G2JU68 R-RNO-381537 https://reactome.org/PathwayBrowser/#/R-RNO-381537 PAPP-A2 proteolyzes IGF:IGFBP5:ALS IEA Rattus norvegicus A0A0G2JU91 R-RNO-173481 https://reactome.org/PathwayBrowser/#/R-RNO-173481 SKI/SKIL binds SMAD complex, suppressing TGF-beta signaling IEA Rattus norvegicus A0A0G2JU91 R-RNO-350058 https://reactome.org/PathwayBrowser/#/R-RNO-350058 Formation of CSL NCOR corepressor complex IEA Rattus norvegicus A0A0G2JU91 R-RNO-382096 https://reactome.org/PathwayBrowser/#/R-RNO-382096 Formation of NR-NCOR Corepressor Complex IEA Rattus norvegicus A0A0G2JU91 R-RNO-400143 https://reactome.org/PathwayBrowser/#/R-RNO-400143 Fatty acid ligands activate PPARA IEA Rattus norvegicus A0A0G2JU91 R-RNO-400183 https://reactome.org/PathwayBrowser/#/R-RNO-400183 PPARA:RXRA binds Corepressors of PPARA IEA Rattus norvegicus A0A0G2JU91 R-RNO-9024326 https://reactome.org/PathwayBrowser/#/R-RNO-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Rattus norvegicus A0A0G2JU91 R-RNO-9024334 https://reactome.org/PathwayBrowser/#/R-RNO-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Rattus norvegicus A0A0G2JU91 R-RNO-9029517 https://reactome.org/PathwayBrowser/#/R-RNO-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Rattus norvegicus A0A0G2JU91 R-RNO-9029566 https://reactome.org/PathwayBrowser/#/R-RNO-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Rattus norvegicus A0A0G2JU91 R-RNO-9732629 https://reactome.org/PathwayBrowser/#/R-RNO-9732629 PPARG binds PPARG agonists IEA Rattus norvegicus A0A0G2JU91 R-RNO-9734475 https://reactome.org/PathwayBrowser/#/R-RNO-9734475 PPARA binds fibrates IEA Rattus norvegicus A0A0G2JU91 R-RNO-9843115 https://reactome.org/PathwayBrowser/#/R-RNO-9843115 Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci IEA Rattus norvegicus A0A0G2JU91 R-RNO-9843117 https://reactome.org/PathwayBrowser/#/R-RNO-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Rattus norvegicus A0A0G2JU91 R-RNO-9843118 https://reactome.org/PathwayBrowser/#/R-RNO-9843118 RXRA binds ligands IEA Rattus norvegicus A0A0G2JUB1 R-RNO-8877451 https://reactome.org/PathwayBrowser/#/R-RNO-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-1170539 https://reactome.org/PathwayBrowser/#/R-RNO-1170539 Prolactin receptor is internalized IEA Rattus norvegicus A0A0G2JUC8 R-RNO-1234159 https://reactome.org/PathwayBrowser/#/R-RNO-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Rattus norvegicus A0A0G2JUC8 R-RNO-1234163 https://reactome.org/PathwayBrowser/#/R-RNO-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Rattus norvegicus A0A0G2JUC8 R-RNO-1234169 https://reactome.org/PathwayBrowser/#/R-RNO-1234169 Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Rattus norvegicus A0A0G2JUC8 R-RNO-1234172 https://reactome.org/PathwayBrowser/#/R-RNO-1234172 Nuclear VBC complex ubiquitinylates HIF-alpha IEA Rattus norvegicus A0A0G2JUC8 R-RNO-1234173 https://reactome.org/PathwayBrowser/#/R-RNO-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Rattus norvegicus A0A0G2JUC8 R-RNO-1234175 https://reactome.org/PathwayBrowser/#/R-RNO-1234175 ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol IEA Rattus norvegicus A0A0G2JUC8 R-RNO-1234177 https://reactome.org/PathwayBrowser/#/R-RNO-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Rattus norvegicus A0A0G2JUC8 R-RNO-1234183 https://reactome.org/PathwayBrowser/#/R-RNO-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Rattus norvegicus A0A0G2JUC8 R-RNO-1370500 https://reactome.org/PathwayBrowser/#/R-RNO-1370500 PRLR binds SCF beta-TrCP complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-1504190 https://reactome.org/PathwayBrowser/#/R-RNO-1504190 DVL is ubiquitinated by CUL3:KLHL12:RBX1 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-1504193 https://reactome.org/PathwayBrowser/#/R-RNO-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Rattus norvegicus A0A0G2JUC8 R-RNO-1504213 https://reactome.org/PathwayBrowser/#/R-RNO-1504213 DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-209063 https://reactome.org/PathwayBrowser/#/R-RNO-209063 Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-2130279 https://reactome.org/PathwayBrowser/#/R-RNO-2130279 Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-2130282 https://reactome.org/PathwayBrowser/#/R-RNO-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Rattus norvegicus A0A0G2JUC8 R-RNO-2130286 https://reactome.org/PathwayBrowser/#/R-RNO-2130286 Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5610742 https://reactome.org/PathwayBrowser/#/R-RNO-5610742 SCF(beta-TrCP) ubiquitinates p-GLI1 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5610746 https://reactome.org/PathwayBrowser/#/R-RNO-5610746 SCF(beta-TrCP) ubiquitinates p-GLI3 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5635854 https://reactome.org/PathwayBrowser/#/R-RNO-5635854 GLI2,3 are degraded by the proteasome IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5635855 https://reactome.org/PathwayBrowser/#/R-RNO-5635855 phosphorylated GLI proteins bind SPOP:CUL3:RBX1 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5635856 https://reactome.org/PathwayBrowser/#/R-RNO-5635856 SPOP:CUL3:RBX1 ubiquitinates GLI2,3 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5652005 https://reactome.org/PathwayBrowser/#/R-RNO-5652005 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5652009 https://reactome.org/PathwayBrowser/#/R-RNO-5652009 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5658424 https://reactome.org/PathwayBrowser/#/R-RNO-5658424 KBTBD7:CUL3:RBX1 ubiquitinates NF1 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5689317 https://reactome.org/PathwayBrowser/#/R-RNO-5689317 Formation of the pre-incision complex in GG-NER IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5689861 https://reactome.org/PathwayBrowser/#/R-RNO-5689861 Recruitment of XPA and release of CAK IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5690213 https://reactome.org/PathwayBrowser/#/R-RNO-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5690988 https://reactome.org/PathwayBrowser/#/R-RNO-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5690990 https://reactome.org/PathwayBrowser/#/R-RNO-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5690991 https://reactome.org/PathwayBrowser/#/R-RNO-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5690996 https://reactome.org/PathwayBrowser/#/R-RNO-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5691000 https://reactome.org/PathwayBrowser/#/R-RNO-5691000 TFIIH binds GG-NER site to form a verification complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5691006 https://reactome.org/PathwayBrowser/#/R-RNO-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5696655 https://reactome.org/PathwayBrowser/#/R-RNO-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5696664 https://reactome.org/PathwayBrowser/#/R-RNO-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Rattus norvegicus A0A0G2JUC8 R-RNO-5696670 https://reactome.org/PathwayBrowser/#/R-RNO-5696670 CHD1L is recruited to GG-NER site IEA Rattus norvegicus A0A0G2JUC8 R-RNO-6781833 https://reactome.org/PathwayBrowser/#/R-RNO-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Rattus norvegicus A0A0G2JUC8 R-RNO-6781867 https://reactome.org/PathwayBrowser/#/R-RNO-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Rattus norvegicus A0A0G2JUC8 R-RNO-6782004 https://reactome.org/PathwayBrowser/#/R-RNO-6782004 Assembly of the pre-incision complex in TC-NER IEA Rattus norvegicus A0A0G2JUC8 R-RNO-6782069 https://reactome.org/PathwayBrowser/#/R-RNO-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-6782131 https://reactome.org/PathwayBrowser/#/R-RNO-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Rattus norvegicus A0A0G2JUC8 R-RNO-6782138 https://reactome.org/PathwayBrowser/#/R-RNO-6782138 ERCC5 and RPA bind TC-NER site IEA Rattus norvegicus A0A0G2JUC8 R-RNO-6782141 https://reactome.org/PathwayBrowser/#/R-RNO-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Rattus norvegicus A0A0G2JUC8 R-RNO-6782204 https://reactome.org/PathwayBrowser/#/R-RNO-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Rattus norvegicus A0A0G2JUC8 R-RNO-6782208 https://reactome.org/PathwayBrowser/#/R-RNO-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Rattus norvegicus A0A0G2JUC8 R-RNO-6782211 https://reactome.org/PathwayBrowser/#/R-RNO-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Rattus norvegicus A0A0G2JUC8 R-RNO-6782224 https://reactome.org/PathwayBrowser/#/R-RNO-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Rattus norvegicus A0A0G2JUC8 R-RNO-6782227 https://reactome.org/PathwayBrowser/#/R-RNO-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Rattus norvegicus A0A0G2JUC8 R-RNO-6782943 https://reactome.org/PathwayBrowser/#/R-RNO-6782943 UV-DDB ubiquitinates XPC IEA Rattus norvegicus A0A0G2JUC8 R-RNO-6790454 https://reactome.org/PathwayBrowser/#/R-RNO-6790454 SUMOylation of XPC IEA Rattus norvegicus A0A0G2JUC8 R-RNO-68946 https://reactome.org/PathwayBrowser/#/R-RNO-68946 Phosphorylated Orc1 is ubiquitinated while still associated with chromatin IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8853496 https://reactome.org/PathwayBrowser/#/R-RNO-8853496 SCF:FBXL7 binds AURKA IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8854041 https://reactome.org/PathwayBrowser/#/R-RNO-8854041 SCF-FBXL7 ubiquitinates AURKA IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8854044 https://reactome.org/PathwayBrowser/#/R-RNO-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8854051 https://reactome.org/PathwayBrowser/#/R-RNO-8854051 SCF-FBXL18 ubiquitinates FBXL7 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8854052 https://reactome.org/PathwayBrowser/#/R-RNO-8854052 Formation of the SCF-FBXL7 complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8952618 https://reactome.org/PathwayBrowser/#/R-RNO-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8952620 https://reactome.org/PathwayBrowser/#/R-RNO-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8952625 https://reactome.org/PathwayBrowser/#/R-RNO-8952625 NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8952626 https://reactome.org/PathwayBrowser/#/R-RNO-8952626 AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8952630 https://reactome.org/PathwayBrowser/#/R-RNO-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8952631 https://reactome.org/PathwayBrowser/#/R-RNO-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8952638 https://reactome.org/PathwayBrowser/#/R-RNO-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8952639 https://reactome.org/PathwayBrowser/#/R-RNO-8952639 NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8955241 https://reactome.org/PathwayBrowser/#/R-RNO-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8955245 https://reactome.org/PathwayBrowser/#/R-RNO-8955245 CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8955285 https://reactome.org/PathwayBrowser/#/R-RNO-8955285 COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8955289 https://reactome.org/PathwayBrowser/#/R-RNO-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8956025 https://reactome.org/PathwayBrowser/#/R-RNO-8956025 AcM-UBE2M transfers NEDD8 to CUL9:RBX1 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8956026 https://reactome.org/PathwayBrowser/#/R-RNO-8956026 CUL9:RBX1 ubiquitinates BIRC5 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8956031 https://reactome.org/PathwayBrowser/#/R-RNO-8956031 NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8956040 https://reactome.org/PathwayBrowser/#/R-RNO-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8956045 https://reactome.org/PathwayBrowser/#/R-RNO-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8956050 https://reactome.org/PathwayBrowser/#/R-RNO-8956050 NEDD8-CUL9:RBX1 binds CUL7:CCDC8:OBSL1 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8956099 https://reactome.org/PathwayBrowser/#/R-RNO-8956099 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8956103 https://reactome.org/PathwayBrowser/#/R-RNO-8956103 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8956106 https://reactome.org/PathwayBrowser/#/R-RNO-8956106 VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha IEA Rattus norvegicus A0A0G2JUC8 R-RNO-8956200 https://reactome.org/PathwayBrowser/#/R-RNO-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-9684118 https://reactome.org/PathwayBrowser/#/R-RNO-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Rattus norvegicus A0A0G2JUC8 R-RNO-9712274 https://reactome.org/PathwayBrowser/#/R-RNO-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-9755303 https://reactome.org/PathwayBrowser/#/R-RNO-9755303 26S proteasome degrades HIFalpha IEA Rattus norvegicus A0A0G2JUC8 R-RNO-9755505 https://reactome.org/PathwayBrowser/#/R-RNO-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-9755507 https://reactome.org/PathwayBrowser/#/R-RNO-9755507 UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex IEA Rattus norvegicus A0A0G2JUC8 R-RNO-9758090 https://reactome.org/PathwayBrowser/#/R-RNO-9758090 Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation IEA Rattus norvegicus A0A0G2JUC8 R-RNO-9759169 https://reactome.org/PathwayBrowser/#/R-RNO-9759169 p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-9759172 https://reactome.org/PathwayBrowser/#/R-RNO-9759172 KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer IEA Rattus norvegicus A0A0G2JUC8 R-RNO-9762091 https://reactome.org/PathwayBrowser/#/R-RNO-9762091 NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-9762093 https://reactome.org/PathwayBrowser/#/R-RNO-9762093 BTRC binds p-S344, 347 NFE2L2 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-9762096 https://reactome.org/PathwayBrowser/#/R-RNO-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Rattus norvegicus A0A0G2JUC8 R-RNO-9766645 https://reactome.org/PathwayBrowser/#/R-RNO-9766645 CUL3:RBX1 ubiquitinates KEAP1 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-9766656 https://reactome.org/PathwayBrowser/#/R-RNO-9766656 RBX1:CUL3 dissociates from forming autophagosome IEA Rattus norvegicus A0A0G2JUC8 R-RNO-9766677 https://reactome.org/PathwayBrowser/#/R-RNO-9766677 MAP1LC3B binds KEAP1 and SQSTM1 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-9766687 https://reactome.org/PathwayBrowser/#/R-RNO-9766687 SESN1,SESN1 bind SQSTM1 and KEAP1 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-976991 https://reactome.org/PathwayBrowser/#/R-RNO-976991 Prolactin receptor ligands bind the prolactin receptor IEA Rattus norvegicus A0A0G2JUC8 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2JUC8 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus A0A0G2JUC8 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2JUC8 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2JUC9 R-RNO-4551724 https://reactome.org/PathwayBrowser/#/R-RNO-4551724 PIAS4 SUMOylates HERC2 with SUMO1 IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5682586 https://reactome.org/PathwayBrowser/#/R-RNO-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5682598 https://reactome.org/PathwayBrowser/#/R-RNO-5682598 ATM phosphorylates HERC2 IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5682607 https://reactome.org/PathwayBrowser/#/R-RNO-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5682858 https://reactome.org/PathwayBrowser/#/R-RNO-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5682863 https://reactome.org/PathwayBrowser/#/R-RNO-5682863 RNF168 binds DNA DSBs IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5683077 https://reactome.org/PathwayBrowser/#/R-RNO-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5683384 https://reactome.org/PathwayBrowser/#/R-RNO-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5683385 https://reactome.org/PathwayBrowser/#/R-RNO-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5683405 https://reactome.org/PathwayBrowser/#/R-RNO-5683405 PPP5C dephosphorylates TP53BP1 IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5683425 https://reactome.org/PathwayBrowser/#/R-RNO-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5683735 https://reactome.org/PathwayBrowser/#/R-RNO-5683735 CHEK2 is recruited to DNA DSBs IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5683801 https://reactome.org/PathwayBrowser/#/R-RNO-5683801 CHEK2 phosphorylates BRCA1 IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5684052 https://reactome.org/PathwayBrowser/#/R-RNO-5684052 PIAS4 SUMOylates MDC1 IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5686685 https://reactome.org/PathwayBrowser/#/R-RNO-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5686704 https://reactome.org/PathwayBrowser/#/R-RNO-5686704 Activated ATM phosphorylates DCLRE1C IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5686900 https://reactome.org/PathwayBrowser/#/R-RNO-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5693551 https://reactome.org/PathwayBrowser/#/R-RNO-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Rattus norvegicus A0A0G2JUC9 R-RNO-5693566 https://reactome.org/PathwayBrowser/#/R-RNO-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Rattus norvegicus A0A0G2JUC9 R-RNO-69891 https://reactome.org/PathwayBrowser/#/R-RNO-69891 Phosphorylation and activation of CHEK2 by ATM IEA Rattus norvegicus A0A0G2JUC9 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2JUC9 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus A0A0G2JUC9 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2JUC9 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2JUD2 R-RNO-71732 https://reactome.org/PathwayBrowser/#/R-RNO-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Rattus norvegicus A0A0G2JUG1 R-RNO-6805546 https://reactome.org/PathwayBrowser/#/R-RNO-6805546 Keratin type I binds keratin type II IEA Rattus norvegicus A0A0G2JUG1 R-RNO-6805573 https://reactome.org/PathwayBrowser/#/R-RNO-6805573 Keratin type I/type II heterodimers form tetramers IEA Rattus norvegicus A0A0G2JUG1 R-RNO-6806610 https://reactome.org/PathwayBrowser/#/R-RNO-6806610 Keratin filament formation IEA Rattus norvegicus A0A0G2JUG1 R-RNO-6806613 https://reactome.org/PathwayBrowser/#/R-RNO-6806613 Keratin tetramers bind to form unit length filaments IEA Rattus norvegicus A0A0G2JUG1 R-RNO-6806629 https://reactome.org/PathwayBrowser/#/R-RNO-6806629 Formation of tonofilament bundles IEA Rattus norvegicus A0A0G2JUG1 R-RNO-6809393 https://reactome.org/PathwayBrowser/#/R-RNO-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Rattus norvegicus A0A0G2JUG1 R-RNO-6809663 https://reactome.org/PathwayBrowser/#/R-RNO-6809663 Formation of hair keratin fibres IEA Rattus norvegicus A0A0G2JUG1 R-RNO-6810357 https://reactome.org/PathwayBrowser/#/R-RNO-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Rattus norvegicus A0A0G2JUG1 R-RNO-6810937 https://reactome.org/PathwayBrowser/#/R-RNO-6810937 Lamellar bodies bind the early cornified envelope IEA Rattus norvegicus A0A0G2JUG1 R-RNO-6814387 https://reactome.org/PathwayBrowser/#/R-RNO-6814387 CASP14 cleaves filaggrin IEA Rattus norvegicus A0A0G2JUG1 R-RNO-6814734 https://reactome.org/PathwayBrowser/#/R-RNO-6814734 CDSN binds the cornified envelope IEA Rattus norvegicus A0A0G2JUG1 R-RNO-6814764 https://reactome.org/PathwayBrowser/#/R-RNO-6814764 Plasma membrane resorption IEA Rattus norvegicus A0A0G2JUH4 R-RNO-5649705 https://reactome.org/PathwayBrowser/#/R-RNO-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Rattus norvegicus A0A0G2JUH4 R-RNO-5649723 https://reactome.org/PathwayBrowser/#/R-RNO-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Rattus norvegicus A0A0G2JUH4 R-RNO-5649726 https://reactome.org/PathwayBrowser/#/R-RNO-5649726 LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA IEA Rattus norvegicus A0A0G2JUH4 R-RNO-5649734 https://reactome.org/PathwayBrowser/#/R-RNO-5649734 LIG3 ligates NEIL1,NEIL2-generated single strand break IEA Rattus norvegicus A0A0G2JUJ3 R-RNO-8983059 https://reactome.org/PathwayBrowser/#/R-RNO-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex IEA Rattus norvegicus A0A0G2JUP3 R-RNO-205039 https://reactome.org/PathwayBrowser/#/R-RNO-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Rattus norvegicus A0A0G2JUP3 R-RNO-419166 https://reactome.org/PathwayBrowser/#/R-RNO-419166 GEFs activate RhoA,B,C IEA Rattus norvegicus A0A0G2JUP3 R-RNO-8980691 https://reactome.org/PathwayBrowser/#/R-RNO-8980691 RHOA GEFs activate RHOA IEA Rattus norvegicus A0A0G2JUP3 R-RNO-9018747 https://reactome.org/PathwayBrowser/#/R-RNO-9018747 RHOQ GEFs activate RHOQ IEA Rattus norvegicus A0A0G2JUS3 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2JUS5 R-RNO-446200 https://reactome.org/PathwayBrowser/#/R-RNO-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Rattus norvegicus A0A0G2JUT7 R-RNO-5173005 https://reactome.org/PathwayBrowser/#/R-RNO-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Rattus norvegicus A0A0G2JUV4 R-RNO-5419261 https://reactome.org/PathwayBrowser/#/R-RNO-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Rattus norvegicus A0A0G2JUV4 R-RNO-5419264 https://reactome.org/PathwayBrowser/#/R-RNO-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Rattus norvegicus A0A0G2JUV4 R-RNO-5419271 https://reactome.org/PathwayBrowser/#/R-RNO-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Rattus norvegicus A0A0G2JUV4 R-RNO-5419273 https://reactome.org/PathwayBrowser/#/R-RNO-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Rattus norvegicus A0A0G2JUV4 R-RNO-5419281 https://reactome.org/PathwayBrowser/#/R-RNO-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Rattus norvegicus A0A0G2JUW3 R-RNO-6798748 https://reactome.org/PathwayBrowser/#/R-RNO-6798748 Exocytosis of secretory granule lumen proteins IEA Rattus norvegicus A0A0G2JUW3 R-RNO-6800434 https://reactome.org/PathwayBrowser/#/R-RNO-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Rattus norvegicus A0A0G2JUX4 R-RNO-5696947 https://reactome.org/PathwayBrowser/#/R-RNO-5696947 USP47 deubiquitinates POLB IEA Rattus norvegicus A0A0G2JUX8 R-RNO-210289 https://reactome.org/PathwayBrowser/#/R-RNO-210289 Recruitment of SYK to p-DAP12 IEA Rattus norvegicus A0A0G2JUX8 R-RNO-2172126 https://reactome.org/PathwayBrowser/#/R-RNO-2172126 DAP12 interacts with NKG2C IEA Rattus norvegicus A0A0G2JUX8 R-RNO-2395412 https://reactome.org/PathwayBrowser/#/R-RNO-2395412 Phosphorylation of SYK IEA Rattus norvegicus A0A0G2JUX8 R-RNO-2395801 https://reactome.org/PathwayBrowser/#/R-RNO-2395801 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus A0A0G2JUX8 R-RNO-2396594 https://reactome.org/PathwayBrowser/#/R-RNO-2396594 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus A0A0G2JUX8 R-RNO-2424480 https://reactome.org/PathwayBrowser/#/R-RNO-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2JUX8 R-RNO-2424482 https://reactome.org/PathwayBrowser/#/R-RNO-2424482 p85 regulatory unit of PI3K binds p-6Y-SYK IEA Rattus norvegicus A0A0G2JUX8 R-RNO-2424484 https://reactome.org/PathwayBrowser/#/R-RNO-2424484 Phosphorylation of BTK by p-SYK IEA Rattus norvegicus A0A0G2JUX8 R-RNO-2424486 https://reactome.org/PathwayBrowser/#/R-RNO-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Rattus norvegicus A0A0G2JUX8 R-RNO-2424487 https://reactome.org/PathwayBrowser/#/R-RNO-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Rattus norvegicus A0A0G2JUZ5 R-RNO-5693967 https://reactome.org/PathwayBrowser/#/R-RNO-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Rattus norvegicus A0A0G2JV04 R-RNO-8875659 https://reactome.org/PathwayBrowser/#/R-RNO-8875659 RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane IEA Rattus norvegicus A0A0G2JV04 R-RNO-8875661 https://reactome.org/PathwayBrowser/#/R-RNO-8875661 GGA3 associates with activated MET receptor IEA Rattus norvegicus A0A0G2JV12 R-RNO-1650808 https://reactome.org/PathwayBrowser/#/R-RNO-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Rattus norvegicus A0A0G2JV12 R-RNO-1980233 https://reactome.org/PathwayBrowser/#/R-RNO-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Rattus norvegicus A0A0G2JV12 R-RNO-1981104 https://reactome.org/PathwayBrowser/#/R-RNO-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Rattus norvegicus A0A0G2JV12 R-RNO-1981120 https://reactome.org/PathwayBrowser/#/R-RNO-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Rattus norvegicus A0A0G2JV12 R-RNO-1981128 https://reactome.org/PathwayBrowser/#/R-RNO-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Rattus norvegicus A0A0G2JV12 R-RNO-1981157 https://reactome.org/PathwayBrowser/#/R-RNO-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Rattus norvegicus A0A0G2JV12 R-RNO-2002460 https://reactome.org/PathwayBrowser/#/R-RNO-2002460 P4HB binds Collagen chains IEA Rattus norvegicus A0A0G2JV12 R-RNO-2089971 https://reactome.org/PathwayBrowser/#/R-RNO-2089971 Secretion of collagens IEA Rattus norvegicus A0A0G2JV12 R-RNO-2168038 https://reactome.org/PathwayBrowser/#/R-RNO-2168038 Collagen type XV restin release IEA Rattus norvegicus A0A0G2JV12 R-RNO-2213200 https://reactome.org/PathwayBrowser/#/R-RNO-2213200 Release of endostatin-like peptides IEA Rattus norvegicus A0A0G2JV12 R-RNO-8944216 https://reactome.org/PathwayBrowser/#/R-RNO-8944216 Association of procollagen type XV IEA Rattus norvegicus A0A0G2JV12 R-RNO-8948219 https://reactome.org/PathwayBrowser/#/R-RNO-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus A0A0G2JV12 R-RNO-8948222 https://reactome.org/PathwayBrowser/#/R-RNO-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2JV12 R-RNO-8948224 https://reactome.org/PathwayBrowser/#/R-RNO-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2JV12 R-RNO-8948228 https://reactome.org/PathwayBrowser/#/R-RNO-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus A0A0G2JV12 R-RNO-8948231 https://reactome.org/PathwayBrowser/#/R-RNO-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2JV12 R-RNO-8948232 https://reactome.org/PathwayBrowser/#/R-RNO-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Rattus norvegicus A0A0G2JV12 R-RNO-8948234 https://reactome.org/PathwayBrowser/#/R-RNO-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Rattus norvegicus A0A0G2JV16 R-RNO-1011598 https://reactome.org/PathwayBrowser/#/R-RNO-1011598 DOCKs bind to RhoGEFs IEA Rattus norvegicus A0A0G2JV16 R-RNO-9013143 https://reactome.org/PathwayBrowser/#/R-RNO-9013143 RAC1 GEFs activate RAC1 IEA Rattus norvegicus A0A0G2JV16 R-RNO-9013159 https://reactome.org/PathwayBrowser/#/R-RNO-9013159 CDC42 GEFs activate CDC42 IEA Rattus norvegicus A0A0G2JV24 R-RNO-265429 https://reactome.org/PathwayBrowser/#/R-RNO-265429 THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1 IEA Rattus norvegicus A0A0G2JV24 R-RNO-349603 https://reactome.org/PathwayBrowser/#/R-RNO-349603 Interaction of integrin alphaIIb beta 3 with THBS1 (Thrombospondin-1) IEA Rattus norvegicus A0A0G2JV24 R-RNO-382054 https://reactome.org/PathwayBrowser/#/R-RNO-382054 PDGF binds to extracellular matrix proteins IEA Rattus norvegicus A0A0G2JV24 R-RNO-481007 https://reactome.org/PathwayBrowser/#/R-RNO-481007 Exocytosis of platelet alpha granule contents IEA Rattus norvegicus A0A0G2JV24 R-RNO-5173005 https://reactome.org/PathwayBrowser/#/R-RNO-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Rattus norvegicus A0A0G2JV24 R-RNO-5173192 https://reactome.org/PathwayBrowser/#/R-RNO-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Rattus norvegicus A0A0G2JV56 R-RNO-3928578 https://reactome.org/PathwayBrowser/#/R-RNO-3928578 EPH receptors autophosphorylate IEA Rattus norvegicus A0A0G2JV56 R-RNO-3928591 https://reactome.org/PathwayBrowser/#/R-RNO-3928591 EPH:EFN tetramers oligomerise IEA Rattus norvegicus A0A0G2JV56 R-RNO-3928597 https://reactome.org/PathwayBrowser/#/R-RNO-3928597 EPH:EFN dimers tetramerise IEA Rattus norvegicus A0A0G2JV56 R-RNO-3928604 https://reactome.org/PathwayBrowser/#/R-RNO-3928604 SFKs phosphorylate VAV2,3 IEA Rattus norvegicus A0A0G2JV56 R-RNO-3928607 https://reactome.org/PathwayBrowser/#/R-RNO-3928607 p-EPHs bind VAV2,3 IEA Rattus norvegicus A0A0G2JV56 R-RNO-3928628 https://reactome.org/PathwayBrowser/#/R-RNO-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Rattus norvegicus A0A0G2JV56 R-RNO-3928642 https://reactome.org/PathwayBrowser/#/R-RNO-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Rattus norvegicus A0A0G2JV56 R-RNO-3928646 https://reactome.org/PathwayBrowser/#/R-RNO-3928646 EPHAs bind EFNAs IEA Rattus norvegicus A0A0G2JV56 R-RNO-3928651 https://reactome.org/PathwayBrowser/#/R-RNO-3928651 NGEF exchanges GTP for GDP on RHOA IEA Rattus norvegicus A0A0G2JV56 R-RNO-4093327 https://reactome.org/PathwayBrowser/#/R-RNO-4093327 EPHA binds TIAM1 IEA Rattus norvegicus A0A0G2JV76 R-RNO-110376 https://reactome.org/PathwayBrowser/#/R-RNO-110376 Recruitment of LIG3:XRCC1 complex to the site of repair by POLB IEA Rattus norvegicus A0A0G2JV76 R-RNO-5649705 https://reactome.org/PathwayBrowser/#/R-RNO-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Rattus norvegicus A0A0G2JV76 R-RNO-5649723 https://reactome.org/PathwayBrowser/#/R-RNO-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Rattus norvegicus A0A0G2JV76 R-RNO-5649726 https://reactome.org/PathwayBrowser/#/R-RNO-5649726 LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA IEA Rattus norvegicus A0A0G2JV76 R-RNO-5649734 https://reactome.org/PathwayBrowser/#/R-RNO-5649734 LIG3 ligates NEIL1,NEIL2-generated single strand break IEA Rattus norvegicus A0A0G2JV76 R-RNO-5687673 https://reactome.org/PathwayBrowser/#/R-RNO-5687673 MRN recruits LIG3:XRCC1 to MMEJ sites IEA Rattus norvegicus A0A0G2JV76 R-RNO-5687675 https://reactome.org/PathwayBrowser/#/R-RNO-5687675 LIG3 ligates remaining SSBs in MMEJ IEA Rattus norvegicus A0A0G2JV76 R-RNO-6782227 https://reactome.org/PathwayBrowser/#/R-RNO-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Rattus norvegicus A0A0G2JV76 R-RNO-73931 https://reactome.org/PathwayBrowser/#/R-RNO-73931 LIG3-mediated DNA ligation via the single-nucleotide replacement pathway IEA Rattus norvegicus A0A0G2JV76 R-RNO-73932 https://reactome.org/PathwayBrowser/#/R-RNO-73932 Resynthesis of excised residue by POLB IEA Rattus norvegicus A0A0G2JVD3 R-RNO-3215448 https://reactome.org/PathwayBrowser/#/R-RNO-3215448 SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity IEA Rattus norvegicus A0A0G2JVD3 R-RNO-5205799 https://reactome.org/PathwayBrowser/#/R-RNO-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Rattus norvegicus A0A0G2JVD3 R-RNO-5205861 https://reactome.org/PathwayBrowser/#/R-RNO-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Rattus norvegicus A0A0G2JVD3 R-RNO-8938217 https://reactome.org/PathwayBrowser/#/R-RNO-8938217 RUNX1 binds the SWI/SNF complex IEA Rattus norvegicus A0A0G2JVD3 R-RNO-9932437 https://reactome.org/PathwayBrowser/#/R-RNO-9932437 ARID1 binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1 IEA Rattus norvegicus A0A0G2JVD3 R-RNO-9932836 https://reactome.org/PathwayBrowser/#/R-RNO-9932836 DPF1,2,3 binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1 IEA Rattus norvegicus A0A0G2JVD3 R-RNO-9933238 https://reactome.org/PathwayBrowser/#/R-RNO-9933238 SS18-containing ATPase complex binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1:DPF1,2,3 IEA Rattus norvegicus A0A0G2JVD3 R-RNO-9934021 https://reactome.org/PathwayBrowser/#/R-RNO-9934021 Formation of neuronal progenitor BAF (npBAF) IEA Rattus norvegicus A0A0G2JVF0 R-RNO-8981637 https://reactome.org/PathwayBrowser/#/R-RNO-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Rattus norvegicus A0A0G2JVF0 R-RNO-9013144 https://reactome.org/PathwayBrowser/#/R-RNO-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Rattus norvegicus A0A0G2JVF0 R-RNO-9013161 https://reactome.org/PathwayBrowser/#/R-RNO-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Rattus norvegicus A0A0G2JVF7 R-RNO-6809663 https://reactome.org/PathwayBrowser/#/R-RNO-6809663 Formation of hair keratin fibres IEA Rattus norvegicus A0A0G2JVI4 R-RNO-6787540 https://reactome.org/PathwayBrowser/#/R-RNO-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Rattus norvegicus A0A0G2JVK0 R-RNO-8864307 https://reactome.org/PathwayBrowser/#/R-RNO-8864307 TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP IEA Rattus norvegicus A0A0G2JVK0 R-RNO-9008271 https://reactome.org/PathwayBrowser/#/R-RNO-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Rattus norvegicus A0A0G2JVK0 R-RNO-9023860 https://reactome.org/PathwayBrowser/#/R-RNO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Rattus norvegicus A0A0G2JVM2 R-RNO-5694427 https://reactome.org/PathwayBrowser/#/R-RNO-5694427 MIA3 binds procollagen VII IEA Rattus norvegicus A0A0G2JVM2 R-RNO-5694435 https://reactome.org/PathwayBrowser/#/R-RNO-5694435 MIA2 and MIA3 load procollagen VII into COPII vesicles IEA Rattus norvegicus A0A0G2JVM2 R-RNO-5694436 https://reactome.org/PathwayBrowser/#/R-RNO-5694436 MIA2 and MIA3 dissociate from procollagen VII vesicle IEA Rattus norvegicus A0A0G2JVM2 R-RNO-8952289 https://reactome.org/PathwayBrowser/#/R-RNO-8952289 FAM20C phosphorylates FAM20C substrates IEA Rattus norvegicus A0A0G2JVP1 R-RNO-2993898 https://reactome.org/PathwayBrowser/#/R-RNO-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Rattus norvegicus A0A0G2JVP1 R-RNO-2995389 https://reactome.org/PathwayBrowser/#/R-RNO-2995389 ANKLE2 binds VRK1,(VRK2) IEA Rattus norvegicus A0A0G2JVP1 R-RNO-9014467 https://reactome.org/PathwayBrowser/#/R-RNO-9014467 RHOG binds effectors at the ER membrane IEA Rattus norvegicus A0A0G2JVP1 R-RNO-9691174 https://reactome.org/PathwayBrowser/#/R-RNO-9691174 RAC1 binds effectors at the ER membrane IEA Rattus norvegicus A0A0G2JVP1 R-RNO-9693214 https://reactome.org/PathwayBrowser/#/R-RNO-9693214 RHOD binds effectors at the mitochondrial outer membrane IEA Rattus norvegicus A0A0G2JVP1 R-RNO-9714481 https://reactome.org/PathwayBrowser/#/R-RNO-9714481 RAC2 binds effectors at the ER membrane IEA Rattus norvegicus A0A0G2JVP5 R-RNO-430021 https://reactome.org/PathwayBrowser/#/R-RNO-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Rattus norvegicus A0A0G2JVP8 R-RNO-1861789 https://reactome.org/PathwayBrowser/#/R-RNO-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Rattus norvegicus A0A0G2JVS5 R-RNO-196126 https://reactome.org/PathwayBrowser/#/R-RNO-196126 CHOL translocates from cytosol to mitochondrial intermembrane space IEA Rattus norvegicus A0A0G2JVU1 R-RNO-216076 https://reactome.org/PathwayBrowser/#/R-RNO-216076 VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 IEA Rattus norvegicus A0A0G2JVU1 R-RNO-2395320 https://reactome.org/PathwayBrowser/#/R-RNO-2395320 Latent TGF-beta-1 binds integrins IEA Rattus norvegicus A0A0G2JVU1 R-RNO-2396029 https://reactome.org/PathwayBrowser/#/R-RNO-2396029 Latent TGF-beta-3 binds integrins IEA Rattus norvegicus A0A0G2JVW0 R-RNO-2172123 https://reactome.org/PathwayBrowser/#/R-RNO-2172123 Interaction of SIGLEC14/15/16 and DAP12 IEA Rattus norvegicus A0A0G2JVW0 R-RNO-5685607 https://reactome.org/PathwayBrowser/#/R-RNO-5685607 Sialic acid binds SIGLEC IEA Rattus norvegicus A0A0G2JVX3 R-RNO-8981637 https://reactome.org/PathwayBrowser/#/R-RNO-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Rattus norvegicus A0A0G2JVX3 R-RNO-9013144 https://reactome.org/PathwayBrowser/#/R-RNO-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Rattus norvegicus A0A0G2JVX3 R-RNO-9013161 https://reactome.org/PathwayBrowser/#/R-RNO-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Rattus norvegicus A0A0G2JVY2 R-RNO-2168883 https://reactome.org/PathwayBrowser/#/R-RNO-2168883 Haptoglobin:Hemoglobin binds CD163 IEA Rattus norvegicus A0A0G2JVY2 R-RNO-2230938 https://reactome.org/PathwayBrowser/#/R-RNO-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Rattus norvegicus A0A0G2JVY4 R-RNO-6798747 https://reactome.org/PathwayBrowser/#/R-RNO-6798747 Exocytosis of tertiary granule membrane proteins IEA Rattus norvegicus A0A0G2JVY4 R-RNO-6799350 https://reactome.org/PathwayBrowser/#/R-RNO-6799350 Exocytosis of specific granule membrane proteins IEA Rattus norvegicus A0A0G2JVY9 R-RNO-1363303 https://reactome.org/PathwayBrowser/#/R-RNO-1363303 p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-1363306 https://reactome.org/PathwayBrowser/#/R-RNO-1363306 p130 (RBL2) binds Cyclin E/A:CDK2 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-1363311 https://reactome.org/PathwayBrowser/#/R-RNO-1363311 p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-1363314 https://reactome.org/PathwayBrowser/#/R-RNO-1363314 p107 (RBL1) binds CyclinE/A:CDK2 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-163096 https://reactome.org/PathwayBrowser/#/R-RNO-163096 Recruitment of Telomerase RNP to the Telomeric Chromosome End IEA Rattus norvegicus A0A0G2JVY9 R-RNO-170070 https://reactome.org/PathwayBrowser/#/R-RNO-170070 Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes IEA Rattus norvegicus A0A0G2JVY9 R-RNO-170087 https://reactome.org/PathwayBrowser/#/R-RNO-170087 CAK phosphorylates CDK1 bound to CCNA IEA Rattus norvegicus A0A0G2JVY9 R-RNO-170088 https://reactome.org/PathwayBrowser/#/R-RNO-170088 Translocation of CCNA:p-T14-CDK1 to the nucleus IEA Rattus norvegicus A0A0G2JVY9 R-RNO-170116 https://reactome.org/PathwayBrowser/#/R-RNO-170116 PKMYT1 phosphorylates CCNA:CDK1 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-170156 https://reactome.org/PathwayBrowser/#/R-RNO-170156 WEE1 phosphorylates CCNA:CDK1 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-170158 https://reactome.org/PathwayBrowser/#/R-RNO-170158 CDC25A dephosphorylates CCNA:CDK1 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-174054 https://reactome.org/PathwayBrowser/#/R-RNO-174054 Formation of Cyclin A:Cdk2 complexes IEA Rattus norvegicus A0A0G2JVY9 R-RNO-174079 https://reactome.org/PathwayBrowser/#/R-RNO-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-174104 https://reactome.org/PathwayBrowser/#/R-RNO-174104 Ubiquitination of Cyclin A by APC/C:Cdc20 complex IEA Rattus norvegicus A0A0G2JVY9 R-RNO-174110 https://reactome.org/PathwayBrowser/#/R-RNO-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-174164 https://reactome.org/PathwayBrowser/#/R-RNO-174164 Phosphorylation of Cyclin A:Cdk2 at Tyr 15 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-174171 https://reactome.org/PathwayBrowser/#/R-RNO-174171 Association of Cyclin A with the APC/C IEA Rattus norvegicus A0A0G2JVY9 R-RNO-174255 https://reactome.org/PathwayBrowser/#/R-RNO-174255 Degradation multiubiquitinated Cyclin A IEA Rattus norvegicus A0A0G2JVY9 R-RNO-174273 https://reactome.org/PathwayBrowser/#/R-RNO-174273 Translocation of Cyclin A:Cdk2 complexes to the nucleus IEA Rattus norvegicus A0A0G2JVY9 R-RNO-187520 https://reactome.org/PathwayBrowser/#/R-RNO-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-187552 https://reactome.org/PathwayBrowser/#/R-RNO-187552 Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex IEA Rattus norvegicus A0A0G2JVY9 R-RNO-187574 https://reactome.org/PathwayBrowser/#/R-RNO-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Rattus norvegicus A0A0G2JVY9 R-RNO-187575 https://reactome.org/PathwayBrowser/#/R-RNO-187575 Ubiquitination of phospho-p27/p21 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-187916 https://reactome.org/PathwayBrowser/#/R-RNO-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-187934 https://reactome.org/PathwayBrowser/#/R-RNO-187934 Inactivation of Cyclin A:Cdk2 complexes by p27/p21 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-187937 https://reactome.org/PathwayBrowser/#/R-RNO-187937 Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-187948 https://reactome.org/PathwayBrowser/#/R-RNO-187948 Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-187949 https://reactome.org/PathwayBrowser/#/R-RNO-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-187959 https://reactome.org/PathwayBrowser/#/R-RNO-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Rattus norvegicus A0A0G2JVY9 R-RNO-188371 https://reactome.org/PathwayBrowser/#/R-RNO-188371 Association of Cyclin A:Cdk2 with Cdh1 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-3788705 https://reactome.org/PathwayBrowser/#/R-RNO-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-3788708 https://reactome.org/PathwayBrowser/#/R-RNO-3788708 CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-4088024 https://reactome.org/PathwayBrowser/#/R-RNO-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-5684081 https://reactome.org/PathwayBrowser/#/R-RNO-5684081 MRN complex binds CDK2 and RBBP8 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-5684096 https://reactome.org/PathwayBrowser/#/R-RNO-5684096 CDK2 phosphorylates RBBP8 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-5697009 https://reactome.org/PathwayBrowser/#/R-RNO-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-6793661 https://reactome.org/PathwayBrowser/#/R-RNO-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-6805109 https://reactome.org/PathwayBrowser/#/R-RNO-6805109 CDK2 phosphorylates TP53 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-68944 https://reactome.org/PathwayBrowser/#/R-RNO-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-69005 https://reactome.org/PathwayBrowser/#/R-RNO-69005 Cdc6 protein is phosphorylated by CDK IEA Rattus norvegicus A0A0G2JVY9 R-RNO-9686521 https://reactome.org/PathwayBrowser/#/R-RNO-9686521 CDK2:CCNA phosphorylates TERF2 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-9928887 https://reactome.org/PathwayBrowser/#/R-RNO-9928887 Formation of CCNA2:CDK1 complex IEA Rattus norvegicus A0A0G2JVY9 R-RNO-9929514 https://reactome.org/PathwayBrowser/#/R-RNO-9929514 CDK1 phosphorylates CCNA IEA Rattus norvegicus A0A0G2JVY9 R-RNO-9929532 https://reactome.org/PathwayBrowser/#/R-RNO-9929532 CCNA:CDK1 phosphorylates BORA IEA Rattus norvegicus A0A0G2JVY9 R-RNO-9929533 https://reactome.org/PathwayBrowser/#/R-RNO-9929533 CCNA:CDK1 complex translocates to the cytosol IEA Rattus norvegicus A0A0G2JVY9 R-RNO-9929535 https://reactome.org/PathwayBrowser/#/R-RNO-9929535 CCNA:CDK1 phosphorylates WEE1 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-9929717 https://reactome.org/PathwayBrowser/#/R-RNO-9929717 CCNA:CDK1 phosphorylates FZR1 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-9929719 https://reactome.org/PathwayBrowser/#/R-RNO-9929719 CCNA:CDK1 phosphorylates TICRR IEA Rattus norvegicus A0A0G2JVY9 R-RNO-9929720 https://reactome.org/PathwayBrowser/#/R-RNO-9929720 CCNA:CDK1 phosphorylates OBI1 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-9929721 https://reactome.org/PathwayBrowser/#/R-RNO-9929721 CCNA:CDK1 phosphorylates SGO1 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-9929884 https://reactome.org/PathwayBrowser/#/R-RNO-9929884 CCNA:CDK1 phosphorylates HJURP IEA Rattus norvegicus A0A0G2JVY9 R-RNO-9929904 https://reactome.org/PathwayBrowser/#/R-RNO-9929904 CCNA:CDK1 phosphorylates MIS18BP1 IEA Rattus norvegicus A0A0G2JVY9 R-RNO-9929935 https://reactome.org/PathwayBrowser/#/R-RNO-9929935 CCNA:CDK1 phosphorylates CDC25B IEA Rattus norvegicus A0A0G2JW03 R-RNO-1483203 https://reactome.org/PathwayBrowser/#/R-RNO-1483203 PA is dephosphorylated to DAG by LPIN IEA Rattus norvegicus A0A0G2JW03 R-RNO-4419948 https://reactome.org/PathwayBrowser/#/R-RNO-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Rattus norvegicus A0A0G2JW03 R-RNO-5195402 https://reactome.org/PathwayBrowser/#/R-RNO-5195402 CDK1 phosphorylates LPIN IEA Rattus norvegicus A0A0G2JW03 R-RNO-5221130 https://reactome.org/PathwayBrowser/#/R-RNO-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Rattus norvegicus A0A0G2JW03 R-RNO-75899 https://reactome.org/PathwayBrowser/#/R-RNO-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Rattus norvegicus A0A0G2JW29 R-RNO-964737 https://reactome.org/PathwayBrowser/#/R-RNO-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus A0A0G2JW29 R-RNO-964825 https://reactome.org/PathwayBrowser/#/R-RNO-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus A0A0G2JW29 R-RNO-964830 https://reactome.org/PathwayBrowser/#/R-RNO-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus A0A0G2JW33 R-RNO-5607750 https://reactome.org/PathwayBrowser/#/R-RNO-5607750 SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan IEA Rattus norvegicus A0A0G2JW41 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus A0A0G2JW41 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus A0A0G2JW41 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus A0A0G2JW41 R-RNO-173626 https://reactome.org/PathwayBrowser/#/R-RNO-173626 Activation of C1r IEA Rattus norvegicus A0A0G2JW41 R-RNO-173631 https://reactome.org/PathwayBrowser/#/R-RNO-173631 Activation of C1s IEA Rattus norvegicus A0A0G2JW41 R-RNO-1861621 https://reactome.org/PathwayBrowser/#/R-RNO-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2JW41 R-RNO-199161 https://reactome.org/PathwayBrowser/#/R-RNO-199161 Fc gamma receptors interact with antigen-bound IgG IEA Rattus norvegicus A0A0G2JW41 R-RNO-2029268 https://reactome.org/PathwayBrowser/#/R-RNO-2029268 Phosphorylation and activation of PLCG IEA Rattus norvegicus A0A0G2JW41 R-RNO-2029270 https://reactome.org/PathwayBrowser/#/R-RNO-2029270 Recruitment of PLCgamma to membrane IEA Rattus norvegicus A0A0G2JW41 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2JW41 R-RNO-2029272 https://reactome.org/PathwayBrowser/#/R-RNO-2029272 Release of PLCG from FCGR IEA Rattus norvegicus A0A0G2JW41 R-RNO-2029273 https://reactome.org/PathwayBrowser/#/R-RNO-2029273 PI3K binds to p-6Y-SYK IEA Rattus norvegicus A0A0G2JW41 R-RNO-2029451 https://reactome.org/PathwayBrowser/#/R-RNO-2029451 Activation of RAC1 by VAV IEA Rattus norvegicus A0A0G2JW41 R-RNO-2029452 https://reactome.org/PathwayBrowser/#/R-RNO-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Rattus norvegicus A0A0G2JW41 R-RNO-2029453 https://reactome.org/PathwayBrowser/#/R-RNO-2029453 Phosphorylation of VAV IEA Rattus norvegicus A0A0G2JW41 R-RNO-2029455 https://reactome.org/PathwayBrowser/#/R-RNO-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2JW41 R-RNO-2029457 https://reactome.org/PathwayBrowser/#/R-RNO-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2JW41 R-RNO-2029458 https://reactome.org/PathwayBrowser/#/R-RNO-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Rattus norvegicus A0A0G2JW41 R-RNO-2029459 https://reactome.org/PathwayBrowser/#/R-RNO-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Rattus norvegicus A0A0G2JW41 R-RNO-2029467 https://reactome.org/PathwayBrowser/#/R-RNO-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Rattus norvegicus A0A0G2JW41 R-RNO-2029476 https://reactome.org/PathwayBrowser/#/R-RNO-2029476 Role of myosins in phagosome formation IEA Rattus norvegicus A0A0G2JW41 R-RNO-2203516 https://reactome.org/PathwayBrowser/#/R-RNO-2203516 Alpha-1-Microglobulin is cleaved IEA Rattus norvegicus A0A0G2JW41 R-RNO-2454192 https://reactome.org/PathwayBrowser/#/R-RNO-2454192 Allergen dependent IgE bound FCERI aggregation IEA Rattus norvegicus A0A0G2JW41 R-RNO-2454208 https://reactome.org/PathwayBrowser/#/R-RNO-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Rattus norvegicus A0A0G2JW41 R-RNO-2454240 https://reactome.org/PathwayBrowser/#/R-RNO-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Rattus norvegicus A0A0G2JW41 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus A0A0G2JW41 R-RNO-2730843 https://reactome.org/PathwayBrowser/#/R-RNO-2730843 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus A0A0G2JW41 R-RNO-2730851 https://reactome.org/PathwayBrowser/#/R-RNO-2730851 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus A0A0G2JW41 R-RNO-2730882 https://reactome.org/PathwayBrowser/#/R-RNO-2730882 Phosphorylation of PKC-theta IEA Rattus norvegicus A0A0G2JW41 R-RNO-2730884 https://reactome.org/PathwayBrowser/#/R-RNO-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Rattus norvegicus A0A0G2JW41 R-RNO-2730886 https://reactome.org/PathwayBrowser/#/R-RNO-2730886 Phosphorylation of SHC by SYK kinase IEA Rattus norvegicus A0A0G2JW41 R-RNO-5690701 https://reactome.org/PathwayBrowser/#/R-RNO-5690701 SHP1 binds p-CD22 IEA Rattus norvegicus A0A0G2JW41 R-RNO-5690702 https://reactome.org/PathwayBrowser/#/R-RNO-5690702 LYN phosphorylates CD22 IEA Rattus norvegicus A0A0G2JW41 R-RNO-5690740 https://reactome.org/PathwayBrowser/#/R-RNO-5690740 CD22 binds B-cell receptor IEA Rattus norvegicus A0A0G2JW41 R-RNO-8852266 https://reactome.org/PathwayBrowser/#/R-RNO-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Rattus norvegicus A0A0G2JW41 R-RNO-8852481 https://reactome.org/PathwayBrowser/#/R-RNO-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Rattus norvegicus A0A0G2JW41 R-RNO-8858428 https://reactome.org/PathwayBrowser/#/R-RNO-8858428 FCAMR binds IgA IEA Rattus norvegicus A0A0G2JW41 R-RNO-9021306 https://reactome.org/PathwayBrowser/#/R-RNO-9021306 C1-Inh binds and inactivates C1r, C1s IEA Rattus norvegicus A0A0G2JW41 R-RNO-9606151 https://reactome.org/PathwayBrowser/#/R-RNO-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Rattus norvegicus A0A0G2JW41 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus A0A0G2JW41 R-RNO-9724685 https://reactome.org/PathwayBrowser/#/R-RNO-9724685 IgE binds omalizumab IEA Rattus norvegicus A0A0G2JW41 R-RNO-9725206 https://reactome.org/PathwayBrowser/#/R-RNO-9725206 IgE binds FCERI IEA Rattus norvegicus A0A0G2JW41 R-RNO-983696 https://reactome.org/PathwayBrowser/#/R-RNO-983696 The Immunoglobulin of the BCR binds antigen IEA Rattus norvegicus A0A0G2JW41 R-RNO-983700 https://reactome.org/PathwayBrowser/#/R-RNO-983700 SYK binds the activated BCR IEA Rattus norvegicus A0A0G2JW41 R-RNO-983703 https://reactome.org/PathwayBrowser/#/R-RNO-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Rattus norvegicus A0A0G2JW41 R-RNO-983707 https://reactome.org/PathwayBrowser/#/R-RNO-983707 SYK autophosphorylates at the activated BCR IEA Rattus norvegicus A0A0G2JW47 R-RNO-5358510 https://reactome.org/PathwayBrowser/#/R-RNO-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Rattus norvegicus A0A0G2JW47 R-RNO-5358518 https://reactome.org/PathwayBrowser/#/R-RNO-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Rattus norvegicus A0A0G2JW47 R-RNO-5358597 https://reactome.org/PathwayBrowser/#/R-RNO-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Rattus norvegicus A0A0G2JW47 R-RNO-5358599 https://reactome.org/PathwayBrowser/#/R-RNO-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Rattus norvegicus A0A0G2JW47 R-RNO-5444523 https://reactome.org/PathwayBrowser/#/R-RNO-5444523 Formation of MSH1:PMS2 Complex IEA Rattus norvegicus A0A0G2JW59 R-RNO-109699 https://reactome.org/PathwayBrowser/#/R-RNO-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Rattus norvegicus A0A0G2JW59 R-RNO-2316434 https://reactome.org/PathwayBrowser/#/R-RNO-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2JW59 R-RNO-5672965 https://reactome.org/PathwayBrowser/#/R-RNO-5672965 RAS GEFs promote RAS nucleotide exchange IEA Rattus norvegicus A0A0G2JW59 R-RNO-9607304 https://reactome.org/PathwayBrowser/#/R-RNO-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Rattus norvegicus A0A0G2JW59 R-RNO-9698170 https://reactome.org/PathwayBrowser/#/R-RNO-9698170 Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA IEA Rattus norvegicus A0A0G2JW59 R-RNO-9706345 https://reactome.org/PathwayBrowser/#/R-RNO-9706345 Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA IEA Rattus norvegicus A0A0G2JW74 R-RNO-141409 https://reactome.org/PathwayBrowser/#/R-RNO-141409 Mad1 binds kinetochore IEA Rattus norvegicus A0A0G2JW74 R-RNO-141422 https://reactome.org/PathwayBrowser/#/R-RNO-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Rattus norvegicus A0A0G2JW74 R-RNO-141431 https://reactome.org/PathwayBrowser/#/R-RNO-141431 MAD2 associates with the Mad1 kinetochore complex IEA Rattus norvegicus A0A0G2JW74 R-RNO-141439 https://reactome.org/PathwayBrowser/#/R-RNO-141439 Release of activated MAD2 from kinetochores IEA Rattus norvegicus A0A0G2JW74 R-RNO-1638803 https://reactome.org/PathwayBrowser/#/R-RNO-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Rattus norvegicus A0A0G2JW74 R-RNO-1638821 https://reactome.org/PathwayBrowser/#/R-RNO-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Rattus norvegicus A0A0G2JW74 R-RNO-2213248 https://reactome.org/PathwayBrowser/#/R-RNO-2213248 Transport of antigen loaded MHC II molecules to surface IEA Rattus norvegicus A0A0G2JW74 R-RNO-2467809 https://reactome.org/PathwayBrowser/#/R-RNO-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Rattus norvegicus A0A0G2JW74 R-RNO-2467811 https://reactome.org/PathwayBrowser/#/R-RNO-2467811 Separation of sister chromatids IEA Rattus norvegicus A0A0G2JW74 R-RNO-2468287 https://reactome.org/PathwayBrowser/#/R-RNO-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Rattus norvegicus A0A0G2JW74 R-RNO-2484822 https://reactome.org/PathwayBrowser/#/R-RNO-2484822 Kinetochore assembly IEA Rattus norvegicus A0A0G2JW74 R-RNO-375302 https://reactome.org/PathwayBrowser/#/R-RNO-375302 Kinetochore capture of astral microtubules IEA Rattus norvegicus A0A0G2JW74 R-RNO-5666129 https://reactome.org/PathwayBrowser/#/R-RNO-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Rattus norvegicus A0A0G2JW74 R-RNO-5666160 https://reactome.org/PathwayBrowser/#/R-RNO-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Rattus norvegicus A0A0G2JW74 R-RNO-5666169 https://reactome.org/PathwayBrowser/#/R-RNO-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Rattus norvegicus A0A0G2JW74 R-RNO-6811423 https://reactome.org/PathwayBrowser/#/R-RNO-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Rattus norvegicus A0A0G2JW74 R-RNO-6811426 https://reactome.org/PathwayBrowser/#/R-RNO-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Rattus norvegicus A0A0G2JW74 R-RNO-9648114 https://reactome.org/PathwayBrowser/#/R-RNO-9648114 EML4 recruits NUDC to mitotic spindle IEA Rattus norvegicus A0A0G2JW74 R-RNO-983259 https://reactome.org/PathwayBrowser/#/R-RNO-983259 Kinesins move along microtubules consuming ATP IEA Rattus norvegicus A0A0G2JW74 R-RNO-983266 https://reactome.org/PathwayBrowser/#/R-RNO-983266 Kinesins bind microtubules IEA Rattus norvegicus A0A0G2JW78 R-RNO-376419 https://reactome.org/PathwayBrowser/#/R-RNO-376419 Formation of NR-MED1 Coactivator Complex IEA Rattus norvegicus A0A0G2JW78 R-RNO-382096 https://reactome.org/PathwayBrowser/#/R-RNO-382096 Formation of NR-NCOR Corepressor Complex IEA Rattus norvegicus A0A0G2JW78 R-RNO-4341072 https://reactome.org/PathwayBrowser/#/R-RNO-4341072 SUMOylation of RARA with SUMO2 IEA Rattus norvegicus A0A0G2JW78 R-RNO-5334854 https://reactome.org/PathwayBrowser/#/R-RNO-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Rattus norvegicus A0A0G2JW78 R-RNO-5634103 https://reactome.org/PathwayBrowser/#/R-RNO-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Rattus norvegicus A0A0G2JW78 R-RNO-9009817 https://reactome.org/PathwayBrowser/#/R-RNO-9009817 Acitretin binds to RAR:RXR IEA Rattus norvegicus A0A0G2JW78 R-RNO-9617067 https://reactome.org/PathwayBrowser/#/R-RNO-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Rattus norvegicus A0A0G2JW96 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2JWB6 R-RNO-2559639 https://reactome.org/PathwayBrowser/#/R-RNO-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Rattus norvegicus A0A0G2JWD3 R-RNO-8952039 https://reactome.org/PathwayBrowser/#/R-RNO-8952039 NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JWD3 R-RNO-8952044 https://reactome.org/PathwayBrowser/#/R-RNO-8952044 AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JWD3 R-RNO-8955241 https://reactome.org/PathwayBrowser/#/R-RNO-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Rattus norvegicus A0A0G2JWD3 R-RNO-8955289 https://reactome.org/PathwayBrowser/#/R-RNO-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Rattus norvegicus A0A0G2JWD3 R-RNO-8956040 https://reactome.org/PathwayBrowser/#/R-RNO-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Rattus norvegicus A0A0G2JWD3 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2JWD3 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus A0A0G2JWD3 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2JWD3 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2JWG1 R-RNO-975814 https://reactome.org/PathwayBrowser/#/R-RNO-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Rattus norvegicus A0A0G2JWH3 R-RNO-2529015 https://reactome.org/PathwayBrowser/#/R-RNO-2529015 Dephosphorylation of CK2-modified condensin I IEA Rattus norvegicus A0A0G2JWH3 R-RNO-2529020 https://reactome.org/PathwayBrowser/#/R-RNO-2529020 CK2 phosphorylates condensin I subunits IEA Rattus norvegicus A0A0G2JWH7 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2JWJ1 R-RNO-2213248 https://reactome.org/PathwayBrowser/#/R-RNO-2213248 Transport of antigen loaded MHC II molecules to surface IEA Rattus norvegicus A0A0G2JWJ1 R-RNO-6811423 https://reactome.org/PathwayBrowser/#/R-RNO-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Rattus norvegicus A0A0G2JWJ1 R-RNO-6811426 https://reactome.org/PathwayBrowser/#/R-RNO-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Rattus norvegicus A0A0G2JWJ1 R-RNO-983259 https://reactome.org/PathwayBrowser/#/R-RNO-983259 Kinesins move along microtubules consuming ATP IEA Rattus norvegicus A0A0G2JWJ1 R-RNO-983266 https://reactome.org/PathwayBrowser/#/R-RNO-983266 Kinesins bind microtubules IEA Rattus norvegicus A0A0G2JWL4 R-RNO-6785342 https://reactome.org/PathwayBrowser/#/R-RNO-6785342 FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex IEA Rattus norvegicus A0A0G2JWL4 R-RNO-6785361 https://reactome.org/PathwayBrowser/#/R-RNO-6785361 Monoubiquitination of FANCD2:FANCI IEA Rattus norvegicus A0A0G2JWL4 R-RNO-6785732 https://reactome.org/PathwayBrowser/#/R-RNO-6785732 DNA nucleases bind monoubiquitinated ID2 complex IEA Rattus norvegicus A0A0G2JWL4 R-RNO-6785986 https://reactome.org/PathwayBrowser/#/R-RNO-6785986 DNA nucleases unhook the interstrand crosslink (ICL) IEA Rattus norvegicus A0A0G2JWL4 R-RNO-6786155 https://reactome.org/PathwayBrowser/#/R-RNO-6786155 POLN binds ICL-DNA IEA Rattus norvegicus A0A0G2JWL4 R-RNO-6786166 https://reactome.org/PathwayBrowser/#/R-RNO-6786166 Translesion synthesis across unhooked ICL by POLN IEA Rattus norvegicus A0A0G2JWL4 R-RNO-6786171 https://reactome.org/PathwayBrowser/#/R-RNO-6786171 FANCD2 deubiquitination by USP1:WDR48 IEA Rattus norvegicus A0A0G2JWL4 R-RNO-6788385 https://reactome.org/PathwayBrowser/#/R-RNO-6788385 The complex of ATR and ATRIP is recruited to ICL-DNA IEA Rattus norvegicus A0A0G2JWL4 R-RNO-6788392 https://reactome.org/PathwayBrowser/#/R-RNO-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Rattus norvegicus A0A0G2JWL4 R-RNO-9835411 https://reactome.org/PathwayBrowser/#/R-RNO-9835411 FA core complex:HSP70s binds PKR IEA Rattus norvegicus A0A0G2JWM7 R-RNO-8987105 https://reactome.org/PathwayBrowser/#/R-RNO-8987105 IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-109639 https://reactome.org/PathwayBrowser/#/R-RNO-109639 Formation of the closed pre-initiation complex IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-111264 https://reactome.org/PathwayBrowser/#/R-RNO-111264 Addition of nucleotides between position +11 and +30 IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-112379 https://reactome.org/PathwayBrowser/#/R-RNO-112379 Recruitment of elongation factors to form elongation complex IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-112383 https://reactome.org/PathwayBrowser/#/R-RNO-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-112385 https://reactome.org/PathwayBrowser/#/R-RNO-112385 Addition of nucleotides leads to transcript elongation IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-113430 https://reactome.org/PathwayBrowser/#/R-RNO-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-5689317 https://reactome.org/PathwayBrowser/#/R-RNO-5689317 Formation of the pre-incision complex in GG-NER IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-5689861 https://reactome.org/PathwayBrowser/#/R-RNO-5689861 Recruitment of XPA and release of CAK IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-5690213 https://reactome.org/PathwayBrowser/#/R-RNO-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-5690988 https://reactome.org/PathwayBrowser/#/R-RNO-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-5690990 https://reactome.org/PathwayBrowser/#/R-RNO-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-5690991 https://reactome.org/PathwayBrowser/#/R-RNO-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-5690996 https://reactome.org/PathwayBrowser/#/R-RNO-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-5691000 https://reactome.org/PathwayBrowser/#/R-RNO-5691000 TFIIH binds GG-NER site to form a verification complex IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-5696670 https://reactome.org/PathwayBrowser/#/R-RNO-5696670 CHD1L is recruited to GG-NER site IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6781818 https://reactome.org/PathwayBrowser/#/R-RNO-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6781824 https://reactome.org/PathwayBrowser/#/R-RNO-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6781833 https://reactome.org/PathwayBrowser/#/R-RNO-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6781840 https://reactome.org/PathwayBrowser/#/R-RNO-6781840 ERCC6 binds stalled RNA Pol II IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6781867 https://reactome.org/PathwayBrowser/#/R-RNO-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6782004 https://reactome.org/PathwayBrowser/#/R-RNO-6782004 Assembly of the pre-incision complex in TC-NER IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6782069 https://reactome.org/PathwayBrowser/#/R-RNO-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6782131 https://reactome.org/PathwayBrowser/#/R-RNO-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6782138 https://reactome.org/PathwayBrowser/#/R-RNO-6782138 ERCC5 and RPA bind TC-NER site IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6782141 https://reactome.org/PathwayBrowser/#/R-RNO-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6782204 https://reactome.org/PathwayBrowser/#/R-RNO-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6782208 https://reactome.org/PathwayBrowser/#/R-RNO-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6782211 https://reactome.org/PathwayBrowser/#/R-RNO-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6782224 https://reactome.org/PathwayBrowser/#/R-RNO-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6782227 https://reactome.org/PathwayBrowser/#/R-RNO-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6790454 https://reactome.org/PathwayBrowser/#/R-RNO-6790454 SUMOylation of XPC IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6797606 https://reactome.org/PathwayBrowser/#/R-RNO-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-6797616 https://reactome.org/PathwayBrowser/#/R-RNO-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-73758 https://reactome.org/PathwayBrowser/#/R-RNO-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-73769 https://reactome.org/PathwayBrowser/#/R-RNO-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-73946 https://reactome.org/PathwayBrowser/#/R-RNO-73946 Abortive initiation after formation of the first phosphodiester bond IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-74986 https://reactome.org/PathwayBrowser/#/R-RNO-74986 Elongation of pre-rRNA transcript IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-74993 https://reactome.org/PathwayBrowser/#/R-RNO-74993 PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-75850 https://reactome.org/PathwayBrowser/#/R-RNO-75850 Addition of the third nucleotide on the nascent transcript IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-75856 https://reactome.org/PathwayBrowser/#/R-RNO-75856 Abortive Initiation Before Second Transition IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-75861 https://reactome.org/PathwayBrowser/#/R-RNO-75861 NTP Binds Active Site of RNA Polymerase II IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-75862 https://reactome.org/PathwayBrowser/#/R-RNO-75862 Fall Back to Closed Pre-initiation Complex IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-75864 https://reactome.org/PathwayBrowser/#/R-RNO-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-75866 https://reactome.org/PathwayBrowser/#/R-RNO-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-75869 https://reactome.org/PathwayBrowser/#/R-RNO-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-75873 https://reactome.org/PathwayBrowser/#/R-RNO-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-75891 https://reactome.org/PathwayBrowser/#/R-RNO-75891 Abortive Initiation After Second Transition IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-75949 https://reactome.org/PathwayBrowser/#/R-RNO-75949 RNA Polymerase II Promoter Opening: First Transition IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-76576 https://reactome.org/PathwayBrowser/#/R-RNO-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-77068 https://reactome.org/PathwayBrowser/#/R-RNO-77068 Activation of GT IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-77069 https://reactome.org/PathwayBrowser/#/R-RNO-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-77071 https://reactome.org/PathwayBrowser/#/R-RNO-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-77073 https://reactome.org/PathwayBrowser/#/R-RNO-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-77077 https://reactome.org/PathwayBrowser/#/R-RNO-77077 Capping complex formation IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-77078 https://reactome.org/PathwayBrowser/#/R-RNO-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-77081 https://reactome.org/PathwayBrowser/#/R-RNO-77081 Formation of the CE:GMP intermediate complex IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-77083 https://reactome.org/PathwayBrowser/#/R-RNO-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-77085 https://reactome.org/PathwayBrowser/#/R-RNO-77085 Dissociation of transcript with 5'-GMP from GT IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-77090 https://reactome.org/PathwayBrowser/#/R-RNO-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-9613494 https://reactome.org/PathwayBrowser/#/R-RNO-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-9613497 https://reactome.org/PathwayBrowser/#/R-RNO-9613497 Unwinding DNA for the nascent transcript IEA Rattus norvegicus A0A0G2JWQ0 R-RNO-9684118 https://reactome.org/PathwayBrowser/#/R-RNO-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Rattus norvegicus A0A0G2JWQ8 R-RNO-939763 https://reactome.org/PathwayBrowser/#/R-RNO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Rattus norvegicus A0A0G2JWQ8 R-RNO-947591 https://reactome.org/PathwayBrowser/#/R-RNO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Rattus norvegicus A0A0G2JWT6 R-RNO-9603775 https://reactome.org/PathwayBrowser/#/R-RNO-9603775 PEX3:PEX19:class I PMP dissociates IEA Rattus norvegicus A0A0G2JWT6 R-RNO-9603784 https://reactome.org/PathwayBrowser/#/R-RNO-9603784 PEX19:class I PMP binds PEX3 IEA Rattus norvegicus A0A0G2JWT6 R-RNO-9603804 https://reactome.org/PathwayBrowser/#/R-RNO-9603804 PEX19 binds class I peroxisomal membrane proteins IEA Rattus norvegicus A0A0G2JWU0 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2JWW8 R-RNO-9843120 https://reactome.org/PathwayBrowser/#/R-RNO-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Rattus norvegicus A0A0G2JWX9 R-RNO-2684901 https://reactome.org/PathwayBrowser/#/R-RNO-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Rattus norvegicus A0A0G2JWX9 R-RNO-2744242 https://reactome.org/PathwayBrowser/#/R-RNO-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Rattus norvegicus A0A0G2JWX9 R-RNO-2744361 https://reactome.org/PathwayBrowser/#/R-RNO-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Rattus norvegicus A0A0G2JWX9 R-RNO-5333671 https://reactome.org/PathwayBrowser/#/R-RNO-5333671 CLCAs self cleave IEA Rattus norvegicus A0A0G2JWX9 R-RNO-9659568 https://reactome.org/PathwayBrowser/#/R-RNO-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Rattus norvegicus A0A0G2JWY4 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2JX31 R-RNO-163090 https://reactome.org/PathwayBrowser/#/R-RNO-163090 Elongation Of The Telomeric Chromosome End IEA Rattus norvegicus A0A0G2JX31 R-RNO-163096 https://reactome.org/PathwayBrowser/#/R-RNO-163096 Recruitment of Telomerase RNP to the Telomeric Chromosome End IEA Rattus norvegicus A0A0G2JX31 R-RNO-163099 https://reactome.org/PathwayBrowser/#/R-RNO-163099 Alignment Of The RNA Template On The Telomeric Chromosome End IEA Rattus norvegicus A0A0G2JX31 R-RNO-163120 https://reactome.org/PathwayBrowser/#/R-RNO-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Rattus norvegicus A0A0G2JX31 R-RNO-164617 https://reactome.org/PathwayBrowser/#/R-RNO-164617 Elongation of Extended Telomeric Chromosome End IEA Rattus norvegicus A0A0G2JX31 R-RNO-164620 https://reactome.org/PathwayBrowser/#/R-RNO-164620 Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End IEA Rattus norvegicus A0A0G2JX31 R-RNO-174425 https://reactome.org/PathwayBrowser/#/R-RNO-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Rattus norvegicus A0A0G2JX31 R-RNO-174427 https://reactome.org/PathwayBrowser/#/R-RNO-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Rattus norvegicus A0A0G2JX31 R-RNO-174438 https://reactome.org/PathwayBrowser/#/R-RNO-174438 Formation of the Flap Intermediate on the C-strand IEA Rattus norvegicus A0A0G2JX31 R-RNO-174439 https://reactome.org/PathwayBrowser/#/R-RNO-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Rattus norvegicus A0A0G2JX31 R-RNO-174441 https://reactome.org/PathwayBrowser/#/R-RNO-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Rattus norvegicus A0A0G2JX31 R-RNO-174444 https://reactome.org/PathwayBrowser/#/R-RNO-174444 Formation of C-strand Okazaki fragments IEA Rattus norvegicus A0A0G2JX31 R-RNO-174445 https://reactome.org/PathwayBrowser/#/R-RNO-174445 RPA binds to the Flap on the C-strand IEA Rattus norvegicus A0A0G2JX31 R-RNO-174446 https://reactome.org/PathwayBrowser/#/R-RNO-174446 Removal of remaining Flap from the C-strand IEA Rattus norvegicus A0A0G2JX31 R-RNO-174447 https://reactome.org/PathwayBrowser/#/R-RNO-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Rattus norvegicus A0A0G2JX31 R-RNO-174448 https://reactome.org/PathwayBrowser/#/R-RNO-174448 Formation of Processive Complex on the C-strand of the telomere IEA Rattus norvegicus A0A0G2JX31 R-RNO-174451 https://reactome.org/PathwayBrowser/#/R-RNO-174451 Recruitment of DNA2 endonuclease to the C strand IEA Rattus norvegicus A0A0G2JX31 R-RNO-174452 https://reactome.org/PathwayBrowser/#/R-RNO-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Rattus norvegicus A0A0G2JX31 R-RNO-174456 https://reactome.org/PathwayBrowser/#/R-RNO-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Rattus norvegicus A0A0G2JX31 R-RNO-176702 https://reactome.org/PathwayBrowser/#/R-RNO-176702 Disassociation of Processive Complex and Completed Telomere End IEA Rattus norvegicus A0A0G2JX31 R-RNO-3785711 https://reactome.org/PathwayBrowser/#/R-RNO-3785711 Telomere shortening during replicative exhaustion IEA Rattus norvegicus A0A0G2JX31 R-RNO-9629195 https://reactome.org/PathwayBrowser/#/R-RNO-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA IEA Rattus norvegicus A0A0G2JX31 R-RNO-9629216 https://reactome.org/PathwayBrowser/#/R-RNO-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Rattus norvegicus A0A0G2JX31 R-RNO-9668597 https://reactome.org/PathwayBrowser/#/R-RNO-9668597 DNA polymerase:primase binds G-strand of the telomere IEA Rattus norvegicus A0A0G2JX31 R-RNO-9686521 https://reactome.org/PathwayBrowser/#/R-RNO-9686521 CDK2:CCNA phosphorylates TERF2 IEA Rattus norvegicus A0A0G2JX31 R-RNO-9686524 https://reactome.org/PathwayBrowser/#/R-RNO-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Rattus norvegicus A0A0G2JX61 R-RNO-8851225 https://reactome.org/PathwayBrowser/#/R-RNO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus A0A0G2JX61 R-RNO-8851234 https://reactome.org/PathwayBrowser/#/R-RNO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus A0A0G2JX78 R-RNO-109415 https://reactome.org/PathwayBrowser/#/R-RNO-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Rattus norvegicus A0A0G2JX93 R-RNO-1112538 https://reactome.org/PathwayBrowser/#/R-RNO-1112538 Phosphorylated STAT1, STAT3 form dimers IEA Rattus norvegicus A0A0G2JX93 R-RNO-1112565 https://reactome.org/PathwayBrowser/#/R-RNO-1112565 Tyrosine phosphorylated IL6ST binds STAT1,STAT3 IEA Rattus norvegicus A0A0G2JX93 R-RNO-1112587 https://reactome.org/PathwayBrowser/#/R-RNO-1112587 STAT1 and STAT3 dimers translocate to the nucleus IEA Rattus norvegicus A0A0G2JX93 R-RNO-1112602 https://reactome.org/PathwayBrowser/#/R-RNO-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Rattus norvegicus A0A0G2JX93 R-RNO-1112604 https://reactome.org/PathwayBrowser/#/R-RNO-1112604 Phosphorylated STATs are released IEA Rattus norvegicus A0A0G2JX93 R-RNO-1112727 https://reactome.org/PathwayBrowser/#/R-RNO-1112727 Serine phosphorylation of STATs IEA Rattus norvegicus A0A0G2JX93 R-RNO-1169406 https://reactome.org/PathwayBrowser/#/R-RNO-1169406 ISGylation of host proteins IEA Rattus norvegicus A0A0G2JX93 R-RNO-1433456 https://reactome.org/PathwayBrowser/#/R-RNO-1433456 Recruitment of STATs IEA Rattus norvegicus A0A0G2JX93 R-RNO-1470009 https://reactome.org/PathwayBrowser/#/R-RNO-1470009 Phosphorylation of STATs IEA Rattus norvegicus A0A0G2JX93 R-RNO-1470010 https://reactome.org/PathwayBrowser/#/R-RNO-1470010 Dimerization of STATs IEA Rattus norvegicus A0A0G2JX93 R-RNO-1470012 https://reactome.org/PathwayBrowser/#/R-RNO-1470012 Disassociation and translocation of STATs to the nucleus IEA Rattus norvegicus A0A0G2JX93 R-RNO-1678841 https://reactome.org/PathwayBrowser/#/R-RNO-1678841 Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 IEA Rattus norvegicus A0A0G2JX93 R-RNO-380782 https://reactome.org/PathwayBrowser/#/R-RNO-380782 STAT binds to the active receptor IEA Rattus norvegicus A0A0G2JX93 R-RNO-6788571 https://reactome.org/PathwayBrowser/#/R-RNO-6788571 STAT1,STAT3,STAT6 bind IL13:IL13R type II IEA Rattus norvegicus A0A0G2JX93 R-RNO-6788582 https://reactome.org/PathwayBrowser/#/R-RNO-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Rattus norvegicus A0A0G2JX93 R-RNO-6788622 https://reactome.org/PathwayBrowser/#/R-RNO-6788622 p-Y-STATs dimerize IEA Rattus norvegicus A0A0G2JX93 R-RNO-6788623 https://reactome.org/PathwayBrowser/#/R-RNO-6788623 p-Y-STATs translocate to nucleus IEA Rattus norvegicus A0A0G2JX93 R-RNO-6788628 https://reactome.org/PathwayBrowser/#/R-RNO-6788628 p-Y-STATs dissociate IEA Rattus norvegicus A0A0G2JX93 R-RNO-873917 https://reactome.org/PathwayBrowser/#/R-RNO-873917 Translocation of STAT1 dimer to nucleus IEA Rattus norvegicus A0A0G2JX93 R-RNO-873921 https://reactome.org/PathwayBrowser/#/R-RNO-873921 Binding of STAT1 to p-IFNGR1 IEA Rattus norvegicus A0A0G2JX93 R-RNO-873922 https://reactome.org/PathwayBrowser/#/R-RNO-873922 Phosphorylation of STAT1 by JAK kinases IEA Rattus norvegicus A0A0G2JX93 R-RNO-873927 https://reactome.org/PathwayBrowser/#/R-RNO-873927 Release of STAT1 dimer from active receptor unit IEA Rattus norvegicus A0A0G2JX93 R-RNO-877281 https://reactome.org/PathwayBrowser/#/R-RNO-877281 PIAS1 binds p-STAT1 dimer IEA Rattus norvegicus A0A0G2JX93 R-RNO-8950441 https://reactome.org/PathwayBrowser/#/R-RNO-8950441 p-Y701-STAT1 and p-Y705-STAT3 dissociate from IL27:IL27 receptor IEA Rattus norvegicus A0A0G2JX93 R-RNO-8950453 https://reactome.org/PathwayBrowser/#/R-RNO-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Rattus norvegicus A0A0G2JX93 R-RNO-8950485 https://reactome.org/PathwayBrowser/#/R-RNO-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction IEA Rattus norvegicus A0A0G2JX93 R-RNO-8950518 https://reactome.org/PathwayBrowser/#/R-RNO-8950518 STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex IEA Rattus norvegicus A0A0G2JX93 R-RNO-8950733 https://reactome.org/PathwayBrowser/#/R-RNO-8950733 p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus IEA Rattus norvegicus A0A0G2JX93 R-RNO-8950782 https://reactome.org/PathwayBrowser/#/R-RNO-8950782 p-STAT1 binds p-STAT3 IEA Rattus norvegicus A0A0G2JX93 R-RNO-8983835 https://reactome.org/PathwayBrowser/#/R-RNO-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Rattus norvegicus A0A0G2JX93 R-RNO-8983841 https://reactome.org/PathwayBrowser/#/R-RNO-8983841 STAT1 associates with IL6ST:IL6ST IEA Rattus norvegicus A0A0G2JX93 R-RNO-8983845 https://reactome.org/PathwayBrowser/#/R-RNO-8983845 p-STAT1 dissociates from IL6ST:IL6ST IEA Rattus norvegicus A0A0G2JX93 R-RNO-8984014 https://reactome.org/PathwayBrowser/#/R-RNO-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Rattus norvegicus A0A0G2JX93 R-RNO-8984021 https://reactome.org/PathwayBrowser/#/R-RNO-8984021 STAT1,STAT3 associate with IL27RA:IL12RB2 receptor IEA Rattus norvegicus A0A0G2JX93 R-RNO-8984023 https://reactome.org/PathwayBrowser/#/R-RNO-8984023 p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor IEA Rattus norvegicus A0A0G2JX93 R-RNO-8985900 https://reactome.org/PathwayBrowser/#/R-RNO-8985900 p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 IEA Rattus norvegicus A0A0G2JX93 R-RNO-8985929 https://reactome.org/PathwayBrowser/#/R-RNO-8985929 IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B IEA Rattus norvegicus A0A0G2JX93 R-RNO-8985943 https://reactome.org/PathwayBrowser/#/R-RNO-8985943 p-Y701-STAT1 dimerizes IEA Rattus norvegicus A0A0G2JX93 R-RNO-8985966 https://reactome.org/PathwayBrowser/#/R-RNO-8985966 p-Y701-STAT1 binds p-Y705-STAT3 IEA Rattus norvegicus A0A0G2JX93 R-RNO-8985981 https://reactome.org/PathwayBrowser/#/R-RNO-8985981 p-Y701-STAT1:p-Y705-STAT3 translocates from the cytosol to the nucleus IEA Rattus norvegicus A0A0G2JX93 R-RNO-8985983 https://reactome.org/PathwayBrowser/#/R-RNO-8985983 p-Y701-STAT1 dimer translocates from the cytosol to the nucleus IEA Rattus norvegicus A0A0G2JX93 R-RNO-8985988 https://reactome.org/PathwayBrowser/#/R-RNO-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Rattus norvegicus A0A0G2JX93 R-RNO-8986985 https://reactome.org/PathwayBrowser/#/R-RNO-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Rattus norvegicus A0A0G2JX93 R-RNO-8987007 https://reactome.org/PathwayBrowser/#/R-RNO-8987007 p-STAT1 dimerizes IEA Rattus norvegicus A0A0G2JX93 R-RNO-8987033 https://reactome.org/PathwayBrowser/#/R-RNO-8987033 p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 IEA Rattus norvegicus A0A0G2JX93 R-RNO-8987080 https://reactome.org/PathwayBrowser/#/R-RNO-8987080 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 IEA Rattus norvegicus A0A0G2JX93 R-RNO-8987097 https://reactome.org/PathwayBrowser/#/R-RNO-8987097 IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3 IEA Rattus norvegicus A0A0G2JX93 R-RNO-8987150 https://reactome.org/PathwayBrowser/#/R-RNO-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Rattus norvegicus A0A0G2JX93 R-RNO-8987218 https://reactome.org/PathwayBrowser/#/R-RNO-8987218 p-STAT1 dimer translocates from the cytosol to the nucleoplasm IEA Rattus norvegicus A0A0G2JX93 R-RNO-8987230 https://reactome.org/PathwayBrowser/#/R-RNO-8987230 p-STAT1 and p-STAT3 dissociates from IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 IEA Rattus norvegicus A0A0G2JX93 R-RNO-8987255 https://reactome.org/PathwayBrowser/#/R-RNO-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Rattus norvegicus A0A0G2JX93 R-RNO-8987266 https://reactome.org/PathwayBrowser/#/R-RNO-8987266 IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 IEA Rattus norvegicus A0A0G2JX93 R-RNO-8987270 https://reactome.org/PathwayBrowser/#/R-RNO-8987270 p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3 IEA Rattus norvegicus A0A0G2JX93 R-RNO-9006870 https://reactome.org/PathwayBrowser/#/R-RNO-9006870 IL21 receptor STAT phosphorylation IEA Rattus norvegicus A0A0G2JX93 R-RNO-9006873 https://reactome.org/PathwayBrowser/#/R-RNO-9006873 IL21 receptor STAT binding IEA Rattus norvegicus A0A0G2JX93 R-RNO-909552 https://reactome.org/PathwayBrowser/#/R-RNO-909552 Phosphorylation of STAT1 at Ser727 IEA Rattus norvegicus A0A0G2JX93 R-RNO-909718 https://reactome.org/PathwayBrowser/#/R-RNO-909718 Formation of p-STAT1 homodimer IEA Rattus norvegicus A0A0G2JX93 R-RNO-909721 https://reactome.org/PathwayBrowser/#/R-RNO-909721 Translocation of ISGF3 complex to nucleus IEA Rattus norvegicus A0A0G2JX93 R-RNO-909722 https://reactome.org/PathwayBrowser/#/R-RNO-909722 Release of p-STAT2:p-STAT1 dimer IEA Rattus norvegicus A0A0G2JX93 R-RNO-909725 https://reactome.org/PathwayBrowser/#/R-RNO-909725 Interaction of IRF9 with p-STAT2:p-STAT1 IEA Rattus norvegicus A0A0G2JX93 R-RNO-913529 https://reactome.org/PathwayBrowser/#/R-RNO-913529 Translocation of p-STAT1:p-STAT1 dimer to nucleus IEA Rattus norvegicus A0A0G2JX93 R-RNO-9710959 https://reactome.org/PathwayBrowser/#/R-RNO-9710959 p-STAT1 dimer binds KPNA1 IEA Rattus norvegicus A0A0G2JX93 R-RNO-9710963 https://reactome.org/PathwayBrowser/#/R-RNO-9710963 p-STAT1dimer:KPNA1 binds KPNB1 IEA Rattus norvegicus A0A0G2JX93 R-RNO-9835443 https://reactome.org/PathwayBrowser/#/R-RNO-9835443 STAT1,STAT3 binds PKR IEA Rattus norvegicus A0A0G2JX93 R-RNO-9865511 https://reactome.org/PathwayBrowser/#/R-RNO-9865511 Phosphorylation of STAT1 on tyrosine-701 is enhanced by p-S172-IKBKE IEA Rattus norvegicus A0A0G2JX93 R-RNO-997309 https://reactome.org/PathwayBrowser/#/R-RNO-997309 Dephosphorylation of STAT1 by SHP2 IEA Rattus norvegicus A0A0G2JX93 R-RNO-997326 https://reactome.org/PathwayBrowser/#/R-RNO-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Rattus norvegicus A0A0G2JX94 R-RNO-2028583 https://reactome.org/PathwayBrowser/#/R-RNO-2028583 Phosphorylation of YAP by LATS2 IEA Rattus norvegicus A0A0G2JX94 R-RNO-2028661 https://reactome.org/PathwayBrowser/#/R-RNO-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Rattus norvegicus A0A0G2JX94 R-RNO-2028724 https://reactome.org/PathwayBrowser/#/R-RNO-2028724 AMOT proteins bind YAP1 IEA Rattus norvegicus A0A0G2JX94 R-RNO-2028735 https://reactome.org/PathwayBrowser/#/R-RNO-2028735 AMOT proteins bind WWTR1 (TAZ) IEA Rattus norvegicus A0A0G2JX94 R-RNO-9761474 https://reactome.org/PathwayBrowser/#/R-RNO-9761474 AMOT-2 binds CDH11 IEA Rattus norvegicus A0A0G2JX95 R-RNO-5687097 https://reactome.org/PathwayBrowser/#/R-RNO-5687097 p-S857 NCOA3 binds ETV4 IEA Rattus norvegicus A0A0G2JXB5 R-RNO-2684901 https://reactome.org/PathwayBrowser/#/R-RNO-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Rattus norvegicus A0A0G2JXC5 R-RNO-3900070 https://reactome.org/PathwayBrowser/#/R-RNO-3900070 SUMOylation of MKL1 with SUMO1 IEA Rattus norvegicus A0A0G2JXC5 R-RNO-5665982 https://reactome.org/PathwayBrowser/#/R-RNO-5665982 RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 IEA Rattus norvegicus A0A0G2JXC5 R-RNO-5665998 https://reactome.org/PathwayBrowser/#/R-RNO-5665998 MKL1 binds SRF IEA Rattus norvegicus A0A0G2JXC5 R-RNO-5665999 https://reactome.org/PathwayBrowser/#/R-RNO-5665999 MKL1 translocates from cytosol to the nucleus IEA Rattus norvegicus A0A0G2JXC5 R-RNO-5666001 https://reactome.org/PathwayBrowser/#/R-RNO-5666001 Profilin:G-actin binds MKL1 IEA Rattus norvegicus A0A0G2JXC5 R-RNO-5666008 https://reactome.org/PathwayBrowser/#/R-RNO-5666008 SCAI binds SRF:MKL1 IEA Rattus norvegicus A0A0G2JXD0 R-RNO-156826 https://reactome.org/PathwayBrowser/#/R-RNO-156826 Dissociation of L13a from the 60s ribosomal subunit IEA Rattus norvegicus A0A0G2JXD0 R-RNO-1799332 https://reactome.org/PathwayBrowser/#/R-RNO-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Rattus norvegicus A0A0G2JXD0 R-RNO-6791218 https://reactome.org/PathwayBrowser/#/R-RNO-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Rattus norvegicus A0A0G2JXD0 R-RNO-72671 https://reactome.org/PathwayBrowser/#/R-RNO-72671 eIF5B:GTP is hydrolyzed and released IEA Rattus norvegicus A0A0G2JXD0 R-RNO-72672 https://reactome.org/PathwayBrowser/#/R-RNO-72672 The 60S subunit joins the translation initiation complex IEA Rattus norvegicus A0A0G2JXD0 R-RNO-72673 https://reactome.org/PathwayBrowser/#/R-RNO-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Rattus norvegicus A0A0G2JXD0 R-RNO-927789 https://reactome.org/PathwayBrowser/#/R-RNO-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Rattus norvegicus A0A0G2JXD0 R-RNO-927813 https://reactome.org/PathwayBrowser/#/R-RNO-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Rattus norvegicus A0A0G2JXD0 R-RNO-927832 https://reactome.org/PathwayBrowser/#/R-RNO-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Rattus norvegicus A0A0G2JXD0 R-RNO-927836 https://reactome.org/PathwayBrowser/#/R-RNO-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Rattus norvegicus A0A0G2JXD0 R-RNO-927889 https://reactome.org/PathwayBrowser/#/R-RNO-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Rattus norvegicus A0A0G2JXE8 R-RNO-1226094 https://reactome.org/PathwayBrowser/#/R-RNO-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Rattus norvegicus A0A0G2JXE8 R-RNO-1226095 https://reactome.org/PathwayBrowser/#/R-RNO-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Rattus norvegicus A0A0G2JXE8 R-RNO-1227670 https://reactome.org/PathwayBrowser/#/R-RNO-1227670 Recruitment of HDAC1 by p130 (RBL2) IEA Rattus norvegicus A0A0G2JXE8 R-RNO-1227671 https://reactome.org/PathwayBrowser/#/R-RNO-1227671 Recruitment of HDAC1 by p107 (RBL1) IEA Rattus norvegicus A0A0G2JXE8 R-RNO-1362261 https://reactome.org/PathwayBrowser/#/R-RNO-1362261 p130 (RBL2) associates with MuvB to form DREAM complex IEA Rattus norvegicus A0A0G2JXE8 R-RNO-1363303 https://reactome.org/PathwayBrowser/#/R-RNO-1363303 p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 IEA Rattus norvegicus A0A0G2JXE8 R-RNO-1363311 https://reactome.org/PathwayBrowser/#/R-RNO-1363311 p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 IEA Rattus norvegicus A0A0G2JXE8 R-RNO-2127257 https://reactome.org/PathwayBrowser/#/R-RNO-2127257 SMAD2/3:SMAD4 heterotrimer forms a complex with RBL1, E2F4/5 and DP1/2 IEA Rattus norvegicus A0A0G2JXE8 R-RNO-8954056 https://reactome.org/PathwayBrowser/#/R-RNO-8954056 E2F6 binds TFDP2 IEA Rattus norvegicus A0A0G2JXE8 R-RNO-8954082 https://reactome.org/PathwayBrowser/#/R-RNO-8954082 E2F6 binds the PRC1 complex IEA Rattus norvegicus A0A0G2JXE8 R-RNO-9018017 https://reactome.org/PathwayBrowser/#/R-RNO-9018017 RB1 binds and inhibits E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus A0A0G2JXI6 R-RNO-481007 https://reactome.org/PathwayBrowser/#/R-RNO-481007 Exocytosis of platelet alpha granule contents IEA Rattus norvegicus A0A0G2JXI9 R-RNO-212222 https://reactome.org/PathwayBrowser/#/R-RNO-212222 PRC2 recruits DNA methyltransferases IEA Rattus norvegicus A0A0G2JXI9 R-RNO-212252 https://reactome.org/PathwayBrowser/#/R-RNO-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Rattus norvegicus A0A0G2JXI9 R-RNO-212263 https://reactome.org/PathwayBrowser/#/R-RNO-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-212269 https://reactome.org/PathwayBrowser/#/R-RNO-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-2172678 https://reactome.org/PathwayBrowser/#/R-RNO-2172678 PHF8 demethylates histone H4K20me1 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-2294580 https://reactome.org/PathwayBrowser/#/R-RNO-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Rattus norvegicus A0A0G2JXI9 R-RNO-2294590 https://reactome.org/PathwayBrowser/#/R-RNO-2294590 PLK1 binds phosphorylated condensin II complex IEA Rattus norvegicus A0A0G2JXI9 R-RNO-2294600 https://reactome.org/PathwayBrowser/#/R-RNO-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-2301205 https://reactome.org/PathwayBrowser/#/R-RNO-2301205 SETD8 monomethylates histone H4 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-3222593 https://reactome.org/PathwayBrowser/#/R-RNO-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-3229089 https://reactome.org/PathwayBrowser/#/R-RNO-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-3229102 https://reactome.org/PathwayBrowser/#/R-RNO-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-3240295 https://reactome.org/PathwayBrowser/#/R-RNO-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-3318415 https://reactome.org/PathwayBrowser/#/R-RNO-3318415 ATF2 acetylates histone H2B, H4 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-3785711 https://reactome.org/PathwayBrowser/#/R-RNO-3785711 Telomere shortening during replicative exhaustion IEA Rattus norvegicus A0A0G2JXI9 R-RNO-3788745 https://reactome.org/PathwayBrowser/#/R-RNO-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-3788748 https://reactome.org/PathwayBrowser/#/R-RNO-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-427337 https://reactome.org/PathwayBrowser/#/R-RNO-427337 MBD2 binds methylcytosine in chromatin IEA Rattus norvegicus A0A0G2JXI9 R-RNO-427514 https://reactome.org/PathwayBrowser/#/R-RNO-427514 eNoSC deacetylates histone H3 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-427527 https://reactome.org/PathwayBrowser/#/R-RNO-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-427528 https://reactome.org/PathwayBrowser/#/R-RNO-427528 Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5250938 https://reactome.org/PathwayBrowser/#/R-RNO-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5578742 https://reactome.org/PathwayBrowser/#/R-RNO-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5625774 https://reactome.org/PathwayBrowser/#/R-RNO-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5625784 https://reactome.org/PathwayBrowser/#/R-RNO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5625796 https://reactome.org/PathwayBrowser/#/R-RNO-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5625797 https://reactome.org/PathwayBrowser/#/R-RNO-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5625848 https://reactome.org/PathwayBrowser/#/R-RNO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5625849 https://reactome.org/PathwayBrowser/#/R-RNO-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5625870 https://reactome.org/PathwayBrowser/#/R-RNO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5682586 https://reactome.org/PathwayBrowser/#/R-RNO-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5682588 https://reactome.org/PathwayBrowser/#/R-RNO-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5682598 https://reactome.org/PathwayBrowser/#/R-RNO-5682598 ATM phosphorylates HERC2 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5682607 https://reactome.org/PathwayBrowser/#/R-RNO-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5682858 https://reactome.org/PathwayBrowser/#/R-RNO-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5682863 https://reactome.org/PathwayBrowser/#/R-RNO-5682863 RNF168 binds DNA DSBs IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5682965 https://reactome.org/PathwayBrowser/#/R-RNO-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5682967 https://reactome.org/PathwayBrowser/#/R-RNO-5682967 WHSC1 binds DNA DSBs IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5682983 https://reactome.org/PathwayBrowser/#/R-RNO-5682983 ATM phosphorylates WHSC1 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5682992 https://reactome.org/PathwayBrowser/#/R-RNO-5682992 KDM4A,B bind H4K20Me2 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5683077 https://reactome.org/PathwayBrowser/#/R-RNO-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5683384 https://reactome.org/PathwayBrowser/#/R-RNO-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5683385 https://reactome.org/PathwayBrowser/#/R-RNO-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5683405 https://reactome.org/PathwayBrowser/#/R-RNO-5683405 PPP5C dephosphorylates TP53BP1 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5683425 https://reactome.org/PathwayBrowser/#/R-RNO-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5683735 https://reactome.org/PathwayBrowser/#/R-RNO-5683735 CHEK2 is recruited to DNA DSBs IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5683801 https://reactome.org/PathwayBrowser/#/R-RNO-5683801 CHEK2 phosphorylates BRCA1 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5683930 https://reactome.org/PathwayBrowser/#/R-RNO-5683930 WICH phosphorylates H2AFX on Y142 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5683964 https://reactome.org/PathwayBrowser/#/R-RNO-5683964 ATM phosphorylates EYA1-4 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5683967 https://reactome.org/PathwayBrowser/#/R-RNO-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5683986 https://reactome.org/PathwayBrowser/#/R-RNO-5683986 APBB1 and MAPK8 bind diphosphorylated H2AFX IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5684052 https://reactome.org/PathwayBrowser/#/R-RNO-5684052 PIAS4 SUMOylates MDC1 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5686685 https://reactome.org/PathwayBrowser/#/R-RNO-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5686704 https://reactome.org/PathwayBrowser/#/R-RNO-5686704 Activated ATM phosphorylates DCLRE1C IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5686900 https://reactome.org/PathwayBrowser/#/R-RNO-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5693536 https://reactome.org/PathwayBrowser/#/R-RNO-5693536 ATM phosphorylates MDC1 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5693549 https://reactome.org/PathwayBrowser/#/R-RNO-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5693551 https://reactome.org/PathwayBrowser/#/R-RNO-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5693566 https://reactome.org/PathwayBrowser/#/R-RNO-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5693583 https://reactome.org/PathwayBrowser/#/R-RNO-5693583 MDC1 associates with gamma-H2AFX at nuclear foci IEA Rattus norvegicus A0A0G2JXI9 R-RNO-5693602 https://reactome.org/PathwayBrowser/#/R-RNO-5693602 ATM recognizes H2AFX-Nucleosomes IEA Rattus norvegicus A0A0G2JXI9 R-RNO-606287 https://reactome.org/PathwayBrowser/#/R-RNO-606287 RSF complex binds the centromere IEA Rattus norvegicus A0A0G2JXI9 R-RNO-69891 https://reactome.org/PathwayBrowser/#/R-RNO-69891 Phosphorylation and activation of CHEK2 by ATM IEA Rattus norvegicus A0A0G2JXI9 R-RNO-73718 https://reactome.org/PathwayBrowser/#/R-RNO-73718 UBF-1 Binds rDNA Promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-74986 https://reactome.org/PathwayBrowser/#/R-RNO-74986 Elongation of pre-rRNA transcript IEA Rattus norvegicus A0A0G2JXI9 R-RNO-8936481 https://reactome.org/PathwayBrowser/#/R-RNO-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-8936584 https://reactome.org/PathwayBrowser/#/R-RNO-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-8936608 https://reactome.org/PathwayBrowser/#/R-RNO-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-8936621 https://reactome.org/PathwayBrowser/#/R-RNO-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-8937016 https://reactome.org/PathwayBrowser/#/R-RNO-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-8937022 https://reactome.org/PathwayBrowser/#/R-RNO-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-8937050 https://reactome.org/PathwayBrowser/#/R-RNO-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-8937113 https://reactome.org/PathwayBrowser/#/R-RNO-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-8942099 https://reactome.org/PathwayBrowser/#/R-RNO-8942099 RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B IEA Rattus norvegicus A0A0G2JXI9 R-RNO-8942101 https://reactome.org/PathwayBrowser/#/R-RNO-8942101 RNF20:RNF40 monoubiquitinates Histone H2B IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9009065 https://reactome.org/PathwayBrowser/#/R-RNO-9009065 FOXA1 and GATA3 bind to CCND1 promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9009371 https://reactome.org/PathwayBrowser/#/R-RNO-9009371 Binding of AP1 transcriptional activator complexes to CCND1 promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9011949 https://reactome.org/PathwayBrowser/#/R-RNO-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9011952 https://reactome.org/PathwayBrowser/#/R-RNO-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9011981 https://reactome.org/PathwayBrowser/#/R-RNO-9011981 EP300 is recruited to MYC and BCL2 genes IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9011984 https://reactome.org/PathwayBrowser/#/R-RNO-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9011985 https://reactome.org/PathwayBrowser/#/R-RNO-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9012000 https://reactome.org/PathwayBrowser/#/R-RNO-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9629195 https://reactome.org/PathwayBrowser/#/R-RNO-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9629216 https://reactome.org/PathwayBrowser/#/R-RNO-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9749197 https://reactome.org/PathwayBrowser/#/R-RNO-9749197 ORC1 binds to H4K20me2 IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9842833 https://reactome.org/PathwayBrowser/#/R-RNO-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9842835 https://reactome.org/PathwayBrowser/#/R-RNO-9842835 KRAB-ZFP binds retroelement DNA in chromatin IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9842839 https://reactome.org/PathwayBrowser/#/R-RNO-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9843115 https://reactome.org/PathwayBrowser/#/R-RNO-9843115 Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9843117 https://reactome.org/PathwayBrowser/#/R-RNO-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9843118 https://reactome.org/PathwayBrowser/#/R-RNO-9843118 RXRA binds ligands IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9843120 https://reactome.org/PathwayBrowser/#/R-RNO-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9843978 https://reactome.org/PathwayBrowser/#/R-RNO-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9844006 https://reactome.org/PathwayBrowser/#/R-RNO-9844006 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9844015 https://reactome.org/PathwayBrowser/#/R-RNO-9844015 MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin IEA Rattus norvegicus A0A0G2JXI9 R-RNO-9844057 https://reactome.org/PathwayBrowser/#/R-RNO-9844057 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome IEA Rattus norvegicus A0A0G2JXJ0 R-RNO-9013145 https://reactome.org/PathwayBrowser/#/R-RNO-9013145 RAC1 binds effectors at the plasma membrane IEA Rattus norvegicus A0A0G2JXJ0 R-RNO-9014294 https://reactome.org/PathwayBrowser/#/R-RNO-9014294 RAC2 binds effectors at the plasma membrane IEA Rattus norvegicus A0A0G2JXJ1 R-RNO-376419 https://reactome.org/PathwayBrowser/#/R-RNO-376419 Formation of NR-MED1 Coactivator Complex IEA Rattus norvegicus A0A0G2JXJ1 R-RNO-382096 https://reactome.org/PathwayBrowser/#/R-RNO-382096 Formation of NR-NCOR Corepressor Complex IEA Rattus norvegicus A0A0G2JXK2 R-RNO-351894 https://reactome.org/PathwayBrowser/#/R-RNO-351894 Caspase mediated cleavage of BAP31 IEA Rattus norvegicus A0A0G2JXK2 R-RNO-351948 https://reactome.org/PathwayBrowser/#/R-RNO-351948 Mitochondrial recruitment of Drp1 IEA Rattus norvegicus A0A0G2JXK2 R-RNO-8951499 https://reactome.org/PathwayBrowser/#/R-RNO-8951499 Loading of antigenic peptides on to class I MHC IEA Rattus norvegicus A0A0G2JXK2 R-RNO-9013004 https://reactome.org/PathwayBrowser/#/R-RNO-9013004 RHOA binds effectors at the ER membrane IEA Rattus norvegicus A0A0G2JXK2 R-RNO-983138 https://reactome.org/PathwayBrowser/#/R-RNO-983138 Transport of MHC heterotrimer to ER exit site IEA Rattus norvegicus A0A0G2JXK2 R-RNO-983142 https://reactome.org/PathwayBrowser/#/R-RNO-983142 Formation of peptide loading complex (PLC) IEA Rattus norvegicus A0A0G2JXK2 R-RNO-983161 https://reactome.org/PathwayBrowser/#/R-RNO-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex IEA Rattus norvegicus A0A0G2JXL5 R-RNO-1964501 https://reactome.org/PathwayBrowser/#/R-RNO-1964501 Addition of galactose to Core 6 glycoprotein IEA Rattus norvegicus A0A0G2JXL5 R-RNO-1964505 https://reactome.org/PathwayBrowser/#/R-RNO-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Rattus norvegicus A0A0G2JXL5 R-RNO-5694487 https://reactome.org/PathwayBrowser/#/R-RNO-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Rattus norvegicus A0A0G2JXL5 R-RNO-6786012 https://reactome.org/PathwayBrowser/#/R-RNO-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Rattus norvegicus A0A0G2JXL5 R-RNO-913675 https://reactome.org/PathwayBrowser/#/R-RNO-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Rattus norvegicus A0A0G2JXL5 R-RNO-914005 https://reactome.org/PathwayBrowser/#/R-RNO-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Rattus norvegicus A0A0G2JXL5 R-RNO-914006 https://reactome.org/PathwayBrowser/#/R-RNO-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Rattus norvegicus A0A0G2JXL5 R-RNO-914008 https://reactome.org/PathwayBrowser/#/R-RNO-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Rattus norvegicus A0A0G2JXL5 R-RNO-914010 https://reactome.org/PathwayBrowser/#/R-RNO-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Rattus norvegicus A0A0G2JXL5 R-RNO-914012 https://reactome.org/PathwayBrowser/#/R-RNO-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Rattus norvegicus A0A0G2JXL5 R-RNO-914017 https://reactome.org/PathwayBrowser/#/R-RNO-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Rattus norvegicus A0A0G2JXL5 R-RNO-914018 https://reactome.org/PathwayBrowser/#/R-RNO-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Rattus norvegicus A0A0G2JXL5 R-RNO-977071 https://reactome.org/PathwayBrowser/#/R-RNO-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Rattus norvegicus A0A0G2JXL5 R-RNO-981497 https://reactome.org/PathwayBrowser/#/R-RNO-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Rattus norvegicus A0A0G2JXL5 R-RNO-981809 https://reactome.org/PathwayBrowser/#/R-RNO-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Rattus norvegicus A0A0G2JXL5 R-RNO-981814 https://reactome.org/PathwayBrowser/#/R-RNO-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Rattus norvegicus A0A0G2JXM1 R-RNO-5357477 https://reactome.org/PathwayBrowser/#/R-RNO-5357477 PAK1-3 phosphorylates VE-cadherin IEA Rattus norvegicus A0A0G2JXM1 R-RNO-9761421 https://reactome.org/PathwayBrowser/#/R-RNO-9761421 CDH11 associates with catenins IEA Rattus norvegicus A0A0G2JXM1 R-RNO-9761474 https://reactome.org/PathwayBrowser/#/R-RNO-9761474 AMOT-2 binds CDH11 IEA Rattus norvegicus A0A0G2JXM1 R-RNO-9762246 https://reactome.org/PathwayBrowser/#/R-RNO-9762246 ANGPTL4 binds CDH11 IEA Rattus norvegicus A0A0G2JXM1 R-RNO-9762282 https://reactome.org/PathwayBrowser/#/R-RNO-9762282 CTNNB1 dissociates from CDH11 upon ANGPTL4 binding IEA Rattus norvegicus A0A0G2JXM2 R-RNO-112379 https://reactome.org/PathwayBrowser/#/R-RNO-112379 Recruitment of elongation factors to form elongation complex IEA Rattus norvegicus A0A0G2JXM2 R-RNO-112381 https://reactome.org/PathwayBrowser/#/R-RNO-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Rattus norvegicus A0A0G2JXM2 R-RNO-112385 https://reactome.org/PathwayBrowser/#/R-RNO-112385 Addition of nucleotides leads to transcript elongation IEA Rattus norvegicus A0A0G2JXM2 R-RNO-112392 https://reactome.org/PathwayBrowser/#/R-RNO-112392 Resumption of elongation after recovery from pausing IEA Rattus norvegicus A0A0G2JXM2 R-RNO-112395 https://reactome.org/PathwayBrowser/#/R-RNO-112395 Abortive termination of elongation after arrest IEA Rattus norvegicus A0A0G2JXM2 R-RNO-112396 https://reactome.org/PathwayBrowser/#/R-RNO-112396 Separation of elongating transcript from template IEA Rattus norvegicus A0A0G2JXM2 R-RNO-112430 https://reactome.org/PathwayBrowser/#/R-RNO-112430 Formation of P-TEFb complex IEA Rattus norvegicus A0A0G2JXM2 R-RNO-113411 https://reactome.org/PathwayBrowser/#/R-RNO-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Rattus norvegicus A0A0G2JXM2 R-RNO-113412 https://reactome.org/PathwayBrowser/#/R-RNO-113412 Pol II elongation complex moves on the template as transcript elongates IEA Rattus norvegicus A0A0G2JXM2 R-RNO-113413 https://reactome.org/PathwayBrowser/#/R-RNO-113413 TFIIS-mediated recovery of elongation from arrest IEA Rattus norvegicus A0A0G2JXM2 R-RNO-113414 https://reactome.org/PathwayBrowser/#/R-RNO-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Rattus norvegicus A0A0G2JXM2 R-RNO-113429 https://reactome.org/PathwayBrowser/#/R-RNO-113429 Elongating transcript encounters a lesion in the template IEA Rattus norvegicus A0A0G2JXM2 R-RNO-2176475 https://reactome.org/PathwayBrowser/#/R-RNO-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Rattus norvegicus A0A0G2JXM2 R-RNO-6797606 https://reactome.org/PathwayBrowser/#/R-RNO-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Rattus norvegicus A0A0G2JXM2 R-RNO-6797616 https://reactome.org/PathwayBrowser/#/R-RNO-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Rattus norvegicus A0A0G2JXM2 R-RNO-6810233 https://reactome.org/PathwayBrowser/#/R-RNO-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Rattus norvegicus A0A0G2JXM2 R-RNO-6810234 https://reactome.org/PathwayBrowser/#/R-RNO-6810234 General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene IEA Rattus norvegicus A0A0G2JXM2 R-RNO-6810235 https://reactome.org/PathwayBrowser/#/R-RNO-6810235 RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain IEA Rattus norvegicus A0A0G2JXM2 R-RNO-6810238 https://reactome.org/PathwayBrowser/#/R-RNO-6810238 RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) IEA Rattus norvegicus A0A0G2JXM2 R-RNO-6814549 https://reactome.org/PathwayBrowser/#/R-RNO-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Rattus norvegicus A0A0G2JXM2 R-RNO-6814555 https://reactome.org/PathwayBrowser/#/R-RNO-6814555 Integrator complex processes the 3' end of snRNA IEA Rattus norvegicus A0A0G2JXM2 R-RNO-6814559 https://reactome.org/PathwayBrowser/#/R-RNO-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Rattus norvegicus A0A0G2JXM2 R-RNO-6814885 https://reactome.org/PathwayBrowser/#/R-RNO-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Rattus norvegicus A0A0G2JXM2 R-RNO-9012315 https://reactome.org/PathwayBrowser/#/R-RNO-9012315 ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene IEA Rattus norvegicus A0A0G2JXM2 R-RNO-9012319 https://reactome.org/PathwayBrowser/#/R-RNO-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Rattus norvegicus A0A0G2JXM5 R-RNO-159101 https://reactome.org/PathwayBrowser/#/R-RNO-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Rattus norvegicus A0A0G2JXM5 R-RNO-72180 https://reactome.org/PathwayBrowser/#/R-RNO-72180 Cleavage of mRNA at the 3'-end IEA Rattus norvegicus A0A0G2JXM5 R-RNO-72185 https://reactome.org/PathwayBrowser/#/R-RNO-72185 mRNA polyadenylation IEA Rattus norvegicus A0A0G2JXM5 R-RNO-75097 https://reactome.org/PathwayBrowser/#/R-RNO-75097 Transport of the export-competent mRNP complex through the NPC IEA Rattus norvegicus A0A0G2JXM5 R-RNO-75098 https://reactome.org/PathwayBrowser/#/R-RNO-75098 mRNP complex dissociates from cytosolic face of NPC IEA Rattus norvegicus A0A0G2JXN8 R-RNO-8867876 https://reactome.org/PathwayBrowser/#/R-RNO-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Rattus norvegicus A0A0G2JXT6 R-RNO-1675994 https://reactome.org/PathwayBrowser/#/R-RNO-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Rattus norvegicus A0A0G2JXT6 R-RNO-1676203 https://reactome.org/PathwayBrowser/#/R-RNO-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Rattus norvegicus A0A0G2JXT6 R-RNO-6809309 https://reactome.org/PathwayBrowser/#/R-RNO-6809309 MTMR6 binds MTMR9 IEA Rattus norvegicus A0A0G2JXT6 R-RNO-6809320 https://reactome.org/PathwayBrowser/#/R-RNO-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Rattus norvegicus A0A0G2JXT6 R-RNO-6809325 https://reactome.org/PathwayBrowser/#/R-RNO-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Rattus norvegicus A0A0G2JXT8 R-RNO-1169398 https://reactome.org/PathwayBrowser/#/R-RNO-1169398 ISGylation of host protein filamin B IEA Rattus norvegicus A0A0G2JXT9 R-RNO-205039 https://reactome.org/PathwayBrowser/#/R-RNO-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Rattus norvegicus A0A0G2JXT9 R-RNO-419166 https://reactome.org/PathwayBrowser/#/R-RNO-419166 GEFs activate RhoA,B,C IEA Rattus norvegicus A0A0G2JXT9 R-RNO-8980691 https://reactome.org/PathwayBrowser/#/R-RNO-8980691 RHOA GEFs activate RHOA IEA Rattus norvegicus A0A0G2JXT9 R-RNO-9013023 https://reactome.org/PathwayBrowser/#/R-RNO-9013023 RHOB GEFs activate RHOB IEA Rattus norvegicus A0A0G2JXY3 R-RNO-2168889 https://reactome.org/PathwayBrowser/#/R-RNO-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Rattus norvegicus A0A0G2JXY3 R-RNO-8952289 https://reactome.org/PathwayBrowser/#/R-RNO-8952289 FAM20C phosphorylates FAM20C substrates IEA Rattus norvegicus A0A0G2JXZ6 R-RNO-6809663 https://reactome.org/PathwayBrowser/#/R-RNO-6809663 Formation of hair keratin fibres IEA Rattus norvegicus A0A0G2JY02 R-RNO-429567 https://reactome.org/PathwayBrowser/#/R-RNO-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Rattus norvegicus A0A0G2JY02 R-RNO-429613 https://reactome.org/PathwayBrowser/#/R-RNO-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Rattus norvegicus A0A0G2JY25 R-RNO-392051 https://reactome.org/PathwayBrowser/#/R-RNO-392051 Recruitment of Grb2 to pFAK:NCAM1 IEA Rattus norvegicus A0A0G2JY25 R-RNO-392053 https://reactome.org/PathwayBrowser/#/R-RNO-392053 SOS binds Grb2 bound to pFAK:NCAM1 IEA Rattus norvegicus A0A0G2JY25 R-RNO-392054 https://reactome.org/PathwayBrowser/#/R-RNO-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Rattus norvegicus A0A0G2JY25 R-RNO-392751 https://reactome.org/PathwayBrowser/#/R-RNO-392751 L1 linked to actin cytoskeleton by ankyrin IEA Rattus norvegicus A0A0G2JY25 R-RNO-5672965 https://reactome.org/PathwayBrowser/#/R-RNO-5672965 RAS GEFs promote RAS nucleotide exchange IEA Rattus norvegicus A0A0G2JY25 R-RNO-6807875 https://reactome.org/PathwayBrowser/#/R-RNO-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Rattus norvegicus A0A0G2JY25 R-RNO-6807877 https://reactome.org/PathwayBrowser/#/R-RNO-6807877 ARFGAPs stimulate ARF GTPase activity IEA Rattus norvegicus A0A0G2JY25 R-RNO-6809003 https://reactome.org/PathwayBrowser/#/R-RNO-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Rattus norvegicus A0A0G2JY25 R-RNO-6809006 https://reactome.org/PathwayBrowser/#/R-RNO-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Rattus norvegicus A0A0G2JY25 R-RNO-6809010 https://reactome.org/PathwayBrowser/#/R-RNO-6809010 COPI vesicle uncoating IEA Rattus norvegicus A0A0G2JY25 R-RNO-6809011 https://reactome.org/PathwayBrowser/#/R-RNO-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Rattus norvegicus A0A0G2JY40 R-RNO-6798748 https://reactome.org/PathwayBrowser/#/R-RNO-6798748 Exocytosis of secretory granule lumen proteins IEA Rattus norvegicus A0A0G2JY40 R-RNO-6800434 https://reactome.org/PathwayBrowser/#/R-RNO-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Rattus norvegicus A0A0G2JY40 R-RNO-8952039 https://reactome.org/PathwayBrowser/#/R-RNO-8952039 NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JY40 R-RNO-8952044 https://reactome.org/PathwayBrowser/#/R-RNO-8952044 AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JY40 R-RNO-8952618 https://reactome.org/PathwayBrowser/#/R-RNO-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JY40 R-RNO-8952620 https://reactome.org/PathwayBrowser/#/R-RNO-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JY40 R-RNO-8952625 https://reactome.org/PathwayBrowser/#/R-RNO-8952625 NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JY40 R-RNO-8952626 https://reactome.org/PathwayBrowser/#/R-RNO-8952626 AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JY40 R-RNO-8952630 https://reactome.org/PathwayBrowser/#/R-RNO-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JY40 R-RNO-8952631 https://reactome.org/PathwayBrowser/#/R-RNO-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JY40 R-RNO-8952638 https://reactome.org/PathwayBrowser/#/R-RNO-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JY40 R-RNO-8952639 https://reactome.org/PathwayBrowser/#/R-RNO-8952639 NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JY40 R-RNO-8955285 https://reactome.org/PathwayBrowser/#/R-RNO-8955285 COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JY40 R-RNO-8955289 https://reactome.org/PathwayBrowser/#/R-RNO-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Rattus norvegicus A0A0G2JY40 R-RNO-8956040 https://reactome.org/PathwayBrowser/#/R-RNO-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Rattus norvegicus A0A0G2JY40 R-RNO-8956045 https://reactome.org/PathwayBrowser/#/R-RNO-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JY40 R-RNO-8956099 https://reactome.org/PathwayBrowser/#/R-RNO-8956099 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 IEA Rattus norvegicus A0A0G2JY40 R-RNO-8956103 https://reactome.org/PathwayBrowser/#/R-RNO-8956103 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha IEA Rattus norvegicus A0A0G2JY40 R-RNO-8956106 https://reactome.org/PathwayBrowser/#/R-RNO-8956106 VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha IEA Rattus norvegicus A0A0G2JY40 R-RNO-8956200 https://reactome.org/PathwayBrowser/#/R-RNO-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2JY40 R-RNO-9755303 https://reactome.org/PathwayBrowser/#/R-RNO-9755303 26S proteasome degrades HIFalpha IEA Rattus norvegicus A0A0G2JY62 R-RNO-1483203 https://reactome.org/PathwayBrowser/#/R-RNO-1483203 PA is dephosphorylated to DAG by LPIN IEA Rattus norvegicus A0A0G2JY62 R-RNO-4419948 https://reactome.org/PathwayBrowser/#/R-RNO-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Rattus norvegicus A0A0G2JY62 R-RNO-5195402 https://reactome.org/PathwayBrowser/#/R-RNO-5195402 CDK1 phosphorylates LPIN IEA Rattus norvegicus A0A0G2JY62 R-RNO-5221130 https://reactome.org/PathwayBrowser/#/R-RNO-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Rattus norvegicus A0A0G2JY62 R-RNO-75899 https://reactome.org/PathwayBrowser/#/R-RNO-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Rattus norvegicus A0A0G2JY80 R-RNO-350058 https://reactome.org/PathwayBrowser/#/R-RNO-350058 Formation of CSL NCOR corepressor complex IEA Rattus norvegicus A0A0G2JY80 R-RNO-400143 https://reactome.org/PathwayBrowser/#/R-RNO-400143 Fatty acid ligands activate PPARA IEA Rattus norvegicus A0A0G2JY80 R-RNO-400183 https://reactome.org/PathwayBrowser/#/R-RNO-400183 PPARA:RXRA binds Corepressors of PPARA IEA Rattus norvegicus A0A0G2JY80 R-RNO-9024326 https://reactome.org/PathwayBrowser/#/R-RNO-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Rattus norvegicus A0A0G2JY80 R-RNO-9024334 https://reactome.org/PathwayBrowser/#/R-RNO-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Rattus norvegicus A0A0G2JY80 R-RNO-9734475 https://reactome.org/PathwayBrowser/#/R-RNO-9734475 PPARA binds fibrates IEA Rattus norvegicus A0A0G2JY80 R-RNO-9843115 https://reactome.org/PathwayBrowser/#/R-RNO-9843115 Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci IEA Rattus norvegicus A0A0G2JY80 R-RNO-9843117 https://reactome.org/PathwayBrowser/#/R-RNO-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Rattus norvegicus A0A0G2JY80 R-RNO-9843118 https://reactome.org/PathwayBrowser/#/R-RNO-9843118 RXRA binds ligands IEA Rattus norvegicus A0A0G2JY83 R-RNO-141341 https://reactome.org/PathwayBrowser/#/R-RNO-141341 SMOX-3 oxidises SPN to SPM IEA Rattus norvegicus A0A0G2JY98 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus A0A0G2JY98 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus A0A0G2JY98 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus A0A0G2JY98 R-RNO-173626 https://reactome.org/PathwayBrowser/#/R-RNO-173626 Activation of C1r IEA Rattus norvegicus A0A0G2JY98 R-RNO-173631 https://reactome.org/PathwayBrowser/#/R-RNO-173631 Activation of C1s IEA Rattus norvegicus A0A0G2JY98 R-RNO-1861621 https://reactome.org/PathwayBrowser/#/R-RNO-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2JY98 R-RNO-199161 https://reactome.org/PathwayBrowser/#/R-RNO-199161 Fc gamma receptors interact with antigen-bound IgG IEA Rattus norvegicus A0A0G2JY98 R-RNO-2029268 https://reactome.org/PathwayBrowser/#/R-RNO-2029268 Phosphorylation and activation of PLCG IEA Rattus norvegicus A0A0G2JY98 R-RNO-2029270 https://reactome.org/PathwayBrowser/#/R-RNO-2029270 Recruitment of PLCgamma to membrane IEA Rattus norvegicus A0A0G2JY98 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2JY98 R-RNO-2029272 https://reactome.org/PathwayBrowser/#/R-RNO-2029272 Release of PLCG from FCGR IEA Rattus norvegicus A0A0G2JY98 R-RNO-2029273 https://reactome.org/PathwayBrowser/#/R-RNO-2029273 PI3K binds to p-6Y-SYK IEA Rattus norvegicus A0A0G2JY98 R-RNO-2029451 https://reactome.org/PathwayBrowser/#/R-RNO-2029451 Activation of RAC1 by VAV IEA Rattus norvegicus A0A0G2JY98 R-RNO-2029452 https://reactome.org/PathwayBrowser/#/R-RNO-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Rattus norvegicus A0A0G2JY98 R-RNO-2029453 https://reactome.org/PathwayBrowser/#/R-RNO-2029453 Phosphorylation of VAV IEA Rattus norvegicus A0A0G2JY98 R-RNO-2029455 https://reactome.org/PathwayBrowser/#/R-RNO-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2JY98 R-RNO-2029457 https://reactome.org/PathwayBrowser/#/R-RNO-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2JY98 R-RNO-2029458 https://reactome.org/PathwayBrowser/#/R-RNO-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Rattus norvegicus A0A0G2JY98 R-RNO-2029459 https://reactome.org/PathwayBrowser/#/R-RNO-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Rattus norvegicus A0A0G2JY98 R-RNO-2029467 https://reactome.org/PathwayBrowser/#/R-RNO-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Rattus norvegicus A0A0G2JY98 R-RNO-2029476 https://reactome.org/PathwayBrowser/#/R-RNO-2029476 Role of myosins in phagosome formation IEA Rattus norvegicus A0A0G2JY98 R-RNO-2203516 https://reactome.org/PathwayBrowser/#/R-RNO-2203516 Alpha-1-Microglobulin is cleaved IEA Rattus norvegicus A0A0G2JY98 R-RNO-2454192 https://reactome.org/PathwayBrowser/#/R-RNO-2454192 Allergen dependent IgE bound FCERI aggregation IEA Rattus norvegicus A0A0G2JY98 R-RNO-2454208 https://reactome.org/PathwayBrowser/#/R-RNO-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Rattus norvegicus A0A0G2JY98 R-RNO-2454240 https://reactome.org/PathwayBrowser/#/R-RNO-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Rattus norvegicus A0A0G2JY98 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus A0A0G2JY98 R-RNO-2730843 https://reactome.org/PathwayBrowser/#/R-RNO-2730843 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus A0A0G2JY98 R-RNO-2730851 https://reactome.org/PathwayBrowser/#/R-RNO-2730851 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus A0A0G2JY98 R-RNO-2730882 https://reactome.org/PathwayBrowser/#/R-RNO-2730882 Phosphorylation of PKC-theta IEA Rattus norvegicus A0A0G2JY98 R-RNO-2730884 https://reactome.org/PathwayBrowser/#/R-RNO-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Rattus norvegicus A0A0G2JY98 R-RNO-2730886 https://reactome.org/PathwayBrowser/#/R-RNO-2730886 Phosphorylation of SHC by SYK kinase IEA Rattus norvegicus A0A0G2JY98 R-RNO-5690701 https://reactome.org/PathwayBrowser/#/R-RNO-5690701 SHP1 binds p-CD22 IEA Rattus norvegicus A0A0G2JY98 R-RNO-5690702 https://reactome.org/PathwayBrowser/#/R-RNO-5690702 LYN phosphorylates CD22 IEA Rattus norvegicus A0A0G2JY98 R-RNO-5690740 https://reactome.org/PathwayBrowser/#/R-RNO-5690740 CD22 binds B-cell receptor IEA Rattus norvegicus A0A0G2JY98 R-RNO-8852266 https://reactome.org/PathwayBrowser/#/R-RNO-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Rattus norvegicus A0A0G2JY98 R-RNO-8852481 https://reactome.org/PathwayBrowser/#/R-RNO-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Rattus norvegicus A0A0G2JY98 R-RNO-8858428 https://reactome.org/PathwayBrowser/#/R-RNO-8858428 FCAMR binds IgA IEA Rattus norvegicus A0A0G2JY98 R-RNO-9021306 https://reactome.org/PathwayBrowser/#/R-RNO-9021306 C1-Inh binds and inactivates C1r, C1s IEA Rattus norvegicus A0A0G2JY98 R-RNO-9606151 https://reactome.org/PathwayBrowser/#/R-RNO-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Rattus norvegicus A0A0G2JY98 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus A0A0G2JY98 R-RNO-9724685 https://reactome.org/PathwayBrowser/#/R-RNO-9724685 IgE binds omalizumab IEA Rattus norvegicus A0A0G2JY98 R-RNO-9725206 https://reactome.org/PathwayBrowser/#/R-RNO-9725206 IgE binds FCERI IEA Rattus norvegicus A0A0G2JY98 R-RNO-983696 https://reactome.org/PathwayBrowser/#/R-RNO-983696 The Immunoglobulin of the BCR binds antigen IEA Rattus norvegicus A0A0G2JY98 R-RNO-983700 https://reactome.org/PathwayBrowser/#/R-RNO-983700 SYK binds the activated BCR IEA Rattus norvegicus A0A0G2JY98 R-RNO-983703 https://reactome.org/PathwayBrowser/#/R-RNO-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Rattus norvegicus A0A0G2JY98 R-RNO-983707 https://reactome.org/PathwayBrowser/#/R-RNO-983707 SYK autophosphorylates at the activated BCR IEA Rattus norvegicus A0A0G2JYA3 R-RNO-8863101 https://reactome.org/PathwayBrowser/#/R-RNO-8863101 SPPL2a/b cleaves TNF(1-76) IEA Rattus norvegicus A0A0G2JYF3 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2JYF3 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus A0A0G2JYF3 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2JYF3 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2JYF7 R-RNO-375140 https://reactome.org/PathwayBrowser/#/R-RNO-375140 CDO binds promyogenic cadherins IEA Rattus norvegicus A0A0G2JYF7 R-RNO-448958 https://reactome.org/PathwayBrowser/#/R-RNO-448958 Nuclear translocation of p38 MAPK IEA Rattus norvegicus A0A0G2JYF9 R-RNO-2424252 https://reactome.org/PathwayBrowser/#/R-RNO-2424252 COMP binds collagen, fibronectin, aggrecan and matrilins IEA Rattus norvegicus A0A0G2JYF9 R-RNO-8952289 https://reactome.org/PathwayBrowser/#/R-RNO-8952289 FAM20C phosphorylates FAM20C substrates IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-2574840 https://reactome.org/PathwayBrowser/#/R-RNO-2574840 AJUBA facilitates AURKA autophosphorylation IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-2574845 https://reactome.org/PathwayBrowser/#/R-RNO-2574845 AJUBA binds centrosome-associated AURKA IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-3000310 https://reactome.org/PathwayBrowser/#/R-RNO-3000310 AURKA phosphorylates PLK1 IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-3000319 https://reactome.org/PathwayBrowser/#/R-RNO-3000319 BORA binds PLK1 and AURKA IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-380272 https://reactome.org/PathwayBrowser/#/R-RNO-380272 Plk1-mediated phosphorylation of Nlp IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-380283 https://reactome.org/PathwayBrowser/#/R-RNO-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-380294 https://reactome.org/PathwayBrowser/#/R-RNO-380294 Loss of C-Nap-1 from centrosomes IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-380303 https://reactome.org/PathwayBrowser/#/R-RNO-380303 Dissociation of Phospho-Nlp from the centrosome IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-380311 https://reactome.org/PathwayBrowser/#/R-RNO-380311 Recruitment of Plk1 to centrosomes IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-380316 https://reactome.org/PathwayBrowser/#/R-RNO-380316 Association of NuMA with microtubules IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-380455 https://reactome.org/PathwayBrowser/#/R-RNO-380455 Recruitment of CDK11p58 to the centrosomes IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-380508 https://reactome.org/PathwayBrowser/#/R-RNO-380508 Translocation of NuMA to the centrosomes IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-5617816 https://reactome.org/PathwayBrowser/#/R-RNO-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-5626220 https://reactome.org/PathwayBrowser/#/R-RNO-5626220 C2CD3 binds the mother centriole IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-5626223 https://reactome.org/PathwayBrowser/#/R-RNO-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-5626227 https://reactome.org/PathwayBrowser/#/R-RNO-5626227 CP110 and CEP97 dissociate from the centriole IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-5626228 https://reactome.org/PathwayBrowser/#/R-RNO-5626228 The distal appendage proteins recruit TTBK2 IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-5626681 https://reactome.org/PathwayBrowser/#/R-RNO-5626681 Recruitment of transition zone proteins IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-5626699 https://reactome.org/PathwayBrowser/#/R-RNO-5626699 MARK4 binds ODF2 in the centriole IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-5638009 https://reactome.org/PathwayBrowser/#/R-RNO-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Rattus norvegicus A0A0G2JYQ1 R-RNO-8853419 https://reactome.org/PathwayBrowser/#/R-RNO-8853419 TPX2 promotes AURKA autophosphorylation IEA Rattus norvegicus A0A0G2JYR5 R-RNO-8981637 https://reactome.org/PathwayBrowser/#/R-RNO-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Rattus norvegicus A0A0G2JYR5 R-RNO-9013009 https://reactome.org/PathwayBrowser/#/R-RNO-9013009 RHOA binds effectors at the plasma membrane IEA Rattus norvegicus A0A0G2JYR5 R-RNO-9013022 https://reactome.org/PathwayBrowser/#/R-RNO-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Rattus norvegicus A0A0G2JYR5 R-RNO-9013024 https://reactome.org/PathwayBrowser/#/R-RNO-9013024 RHOB binds effectors at the plasma membrane IEA Rattus norvegicus A0A0G2JYR5 R-RNO-9013144 https://reactome.org/PathwayBrowser/#/R-RNO-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Rattus norvegicus A0A0G2JYR5 R-RNO-9013161 https://reactome.org/PathwayBrowser/#/R-RNO-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Rattus norvegicus A0A0G2JYR5 R-RNO-9013437 https://reactome.org/PathwayBrowser/#/R-RNO-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Rattus norvegicus A0A0G2JYR5 R-RNO-9014295 https://reactome.org/PathwayBrowser/#/R-RNO-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Rattus norvegicus A0A0G2JYR5 R-RNO-9014434 https://reactome.org/PathwayBrowser/#/R-RNO-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Rattus norvegicus A0A0G2JYR5 R-RNO-9017488 https://reactome.org/PathwayBrowser/#/R-RNO-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Rattus norvegicus A0A0G2JYR5 R-RNO-9018745 https://reactome.org/PathwayBrowser/#/R-RNO-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Rattus norvegicus A0A0G2JYR5 R-RNO-9018746 https://reactome.org/PathwayBrowser/#/R-RNO-9018746 RHOQ binds effectors at the plasma membrane IEA Rattus norvegicus A0A0G2JYR5 R-RNO-9693125 https://reactome.org/PathwayBrowser/#/R-RNO-9693125 RHOF binds effectors at the plasma membrane IEA Rattus norvegicus A0A0G2JYR5 R-RNO-9693198 https://reactome.org/PathwayBrowser/#/R-RNO-9693198 RHOD binds effectors at the plasma membrane IEA Rattus norvegicus A0A0G2JYR5 R-RNO-9693282 https://reactome.org/PathwayBrowser/#/R-RNO-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Rattus norvegicus A0A0G2JYR5 R-RNO-9696266 https://reactome.org/PathwayBrowser/#/R-RNO-9696266 RND2 binds effectors IEA Rattus norvegicus A0A0G2JYU6 R-RNO-5665802 https://reactome.org/PathwayBrowser/#/R-RNO-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Rattus norvegicus A0A0G2JYU6 R-RNO-5665809 https://reactome.org/PathwayBrowser/#/R-RNO-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Rattus norvegicus A0A0G2JYU6 R-RNO-9013145 https://reactome.org/PathwayBrowser/#/R-RNO-9013145 RAC1 binds effectors at the plasma membrane IEA Rattus norvegicus A0A0G2JYV2 R-RNO-72180 https://reactome.org/PathwayBrowser/#/R-RNO-72180 Cleavage of mRNA at the 3'-end IEA Rattus norvegicus A0A0G2JYV2 R-RNO-72185 https://reactome.org/PathwayBrowser/#/R-RNO-72185 mRNA polyadenylation IEA Rattus norvegicus A0A0G2JYV2 R-RNO-72231 https://reactome.org/PathwayBrowser/#/R-RNO-72231 Formation of the Cleavage and Polyadenylation Complex IEA Rattus norvegicus A0A0G2JYV2 R-RNO-77589 https://reactome.org/PathwayBrowser/#/R-RNO-77589 Recognition of AAUAAA sequence by CPSF IEA Rattus norvegicus A0A0G2JYV2 R-RNO-77590 https://reactome.org/PathwayBrowser/#/R-RNO-77590 Recruitment of CstF to the CPSF Bound Pre-mRNA IEA Rattus norvegicus A0A0G2JYV2 R-RNO-77591 https://reactome.org/PathwayBrowser/#/R-RNO-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Rattus norvegicus A0A0G2JYV2 R-RNO-77592 https://reactome.org/PathwayBrowser/#/R-RNO-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Rattus norvegicus A0A0G2JYV2 R-RNO-77593 https://reactome.org/PathwayBrowser/#/R-RNO-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Rattus norvegicus A0A0G2JYV2 R-RNO-77594 https://reactome.org/PathwayBrowser/#/R-RNO-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Rattus norvegicus A0A0G2JYX9 R-RNO-193641 https://reactome.org/PathwayBrowser/#/R-RNO-193641 IKK-beta is recruited IEA Rattus norvegicus A0A0G2JYX9 R-RNO-193665 https://reactome.org/PathwayBrowser/#/R-RNO-193665 MYD88 dissociates IEA Rattus norvegicus A0A0G2JYX9 R-RNO-193684 https://reactome.org/PathwayBrowser/#/R-RNO-193684 p62 recruits an atypical PKC IEA Rattus norvegicus A0A0G2JYX9 R-RNO-193694 https://reactome.org/PathwayBrowser/#/R-RNO-193694 p62 is recruited and forms a complex with TRAF6 IEA Rattus norvegicus A0A0G2JYX9 R-RNO-193695 https://reactome.org/PathwayBrowser/#/R-RNO-193695 IRAK interacts with TRAF6 IEA Rattus norvegicus A0A0G2JYX9 R-RNO-193703 https://reactome.org/PathwayBrowser/#/R-RNO-193703 IKKbeta is activated IEA Rattus norvegicus A0A0G2JYX9 R-RNO-209566 https://reactome.org/PathwayBrowser/#/R-RNO-209566 TRAF6 is auto-ubiquitinated IEA Rattus norvegicus A0A0G2JYX9 R-RNO-2316434 https://reactome.org/PathwayBrowser/#/R-RNO-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2JYX9 R-RNO-446692 https://reactome.org/PathwayBrowser/#/R-RNO-446692 IRAK1 binds to MYD88 within the IL1R complex IEA Rattus norvegicus A0A0G2JYX9 R-RNO-446694 https://reactome.org/PathwayBrowser/#/R-RNO-446694 IRAK4 phosphorylates IRAK1 IEA Rattus norvegicus A0A0G2JYX9 R-RNO-446701 https://reactome.org/PathwayBrowser/#/R-RNO-446701 IRAK4-activated IRAK1 autophosphorylates IEA Rattus norvegicus A0A0G2JYX9 R-RNO-446862 https://reactome.org/PathwayBrowser/#/R-RNO-446862 Hyperphosphorylated IRAK1 associates with TRAF6 IEA Rattus norvegicus A0A0G2JYX9 R-RNO-446870 https://reactome.org/PathwayBrowser/#/R-RNO-446870 Polyubiquitinated TRAF6 binds the TAK1 complex IEA Rattus norvegicus A0A0G2JYX9 R-RNO-446877 https://reactome.org/PathwayBrowser/#/R-RNO-446877 TRAF6 is K63 poly-ubiquitinated IEA Rattus norvegicus A0A0G2JYX9 R-RNO-446894 https://reactome.org/PathwayBrowser/#/R-RNO-446894 TRAF6 binding leads to IRAK1:TRAF6 release IEA Rattus norvegicus A0A0G2JYX9 R-RNO-450173 https://reactome.org/PathwayBrowser/#/R-RNO-450173 IRAK1 induces oligomerisation of TRAF6 IEA Rattus norvegicus A0A0G2JYX9 R-RNO-450187 https://reactome.org/PathwayBrowser/#/R-RNO-450187 TAK1 is activated within the TAK1 complex IEA Rattus norvegicus A0A0G2JYX9 R-RNO-450337 https://reactome.org/PathwayBrowser/#/R-RNO-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Rattus norvegicus A0A0G2JYX9 R-RNO-450346 https://reactome.org/PathwayBrowser/#/R-RNO-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Rattus norvegicus A0A0G2JYX9 R-RNO-450690 https://reactome.org/PathwayBrowser/#/R-RNO-450690 hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 IEA Rattus norvegicus A0A0G2JYX9 R-RNO-450827 https://reactome.org/PathwayBrowser/#/R-RNO-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2 IEA Rattus norvegicus A0A0G2JYX9 R-RNO-451418 https://reactome.org/PathwayBrowser/#/R-RNO-451418 Pellino ubiquitinates IRAK1 IEA Rattus norvegicus A0A0G2JYX9 R-RNO-451561 https://reactome.org/PathwayBrowser/#/R-RNO-451561 NEMO binds polyubiquitinated IRAK1 IEA Rattus norvegicus A0A0G2JYX9 R-RNO-937032 https://reactome.org/PathwayBrowser/#/R-RNO-937032 NEMO subunit of IKK complex binds to activated IRAK1 IEA Rattus norvegicus A0A0G2JYX9 R-RNO-937034 https://reactome.org/PathwayBrowser/#/R-RNO-937034 IRAK1 phosphorylates Pellino IEA Rattus norvegicus A0A0G2JYX9 R-RNO-937044 https://reactome.org/PathwayBrowser/#/R-RNO-937044 Pellino binds hp-IRAK1:TRAF6 IEA Rattus norvegicus A0A0G2JYX9 R-RNO-975119 https://reactome.org/PathwayBrowser/#/R-RNO-975119 NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9 IEA Rattus norvegicus A0A0G2JYX9 R-RNO-975139 https://reactome.org/PathwayBrowser/#/R-RNO-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation IEA Rattus norvegicus A0A0G2JYX9 R-RNO-975142 https://reactome.org/PathwayBrowser/#/R-RNO-975142 Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation IEA Rattus norvegicus A0A0G2JYY6 R-RNO-163217 https://reactome.org/PathwayBrowser/#/R-RNO-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Rattus norvegicus A0A0G2JYY6 R-RNO-9865579 https://reactome.org/PathwayBrowser/#/R-RNO-9865579 MT-CO1 and MT-CO2 complexes associate, installing heme moieties IEA Rattus norvegicus A0A0G2JYZ8 R-RNO-352268 https://reactome.org/PathwayBrowser/#/R-RNO-352268 Cleavage of Satb1 IEA Rattus norvegicus A0A0G2JYZ8 R-RNO-4615839 https://reactome.org/PathwayBrowser/#/R-RNO-4615839 PIAS1 SUMOylates SATB1 with SUMO2,3 IEA Rattus norvegicus A0A0G2JYZ8 R-RNO-4615905 https://reactome.org/PathwayBrowser/#/R-RNO-4615905 PIAS1 SUMOylates SATB1 with SUMO1 IEA Rattus norvegicus A0A0G2JZ01 R-RNO-5683964 https://reactome.org/PathwayBrowser/#/R-RNO-5683964 ATM phosphorylates EYA1-4 IEA Rattus norvegicus A0A0G2JZ01 R-RNO-5683967 https://reactome.org/PathwayBrowser/#/R-RNO-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Rattus norvegicus A0A0G2JZ40 R-RNO-8940388 https://reactome.org/PathwayBrowser/#/R-RNO-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Rattus norvegicus A0A0G2JZ48 R-RNO-6811431 https://reactome.org/PathwayBrowser/#/R-RNO-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Rattus norvegicus A0A0G2JZ48 R-RNO-6814091 https://reactome.org/PathwayBrowser/#/R-RNO-6814091 ARL1 recruits TGN Golgin homodimers IEA Rattus norvegicus A0A0G2JZ48 R-RNO-6814682 https://reactome.org/PathwayBrowser/#/R-RNO-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Rattus norvegicus A0A0G2JZ79 R-RNO-3371467 https://reactome.org/PathwayBrowser/#/R-RNO-3371467 SIRT1 deacetylates HSF1 IEA Rattus norvegicus A0A0G2JZ79 R-RNO-3371518 https://reactome.org/PathwayBrowser/#/R-RNO-3371518 SIRT1 binds to HSF1 IEA Rattus norvegicus A0A0G2JZ79 R-RNO-427514 https://reactome.org/PathwayBrowser/#/R-RNO-427514 eNoSC deacetylates histone H3 IEA Rattus norvegicus A0A0G2JZ79 R-RNO-427527 https://reactome.org/PathwayBrowser/#/R-RNO-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Rattus norvegicus A0A0G2JZ79 R-RNO-427528 https://reactome.org/PathwayBrowser/#/R-RNO-427528 Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) IEA Rattus norvegicus A0A0G2JZ79 R-RNO-9620532 https://reactome.org/PathwayBrowser/#/R-RNO-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Rattus norvegicus A0A0G2JZ79 R-RNO-9825751 https://reactome.org/PathwayBrowser/#/R-RNO-9825751 HINT1 binds MITF-M IEA Rattus norvegicus A0A0G2JZ79 R-RNO-9825772 https://reactome.org/PathwayBrowser/#/R-RNO-9825772 SIRT1 deacetylates HINT1 dimer IEA Rattus norvegicus A0A0G2JZ79 R-RNO-9843115 https://reactome.org/PathwayBrowser/#/R-RNO-9843115 Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci IEA Rattus norvegicus A0A0G2JZA1 R-NUL-9010914 https://reactome.org/PathwayBrowser/#/R-NUL-9010914 Robo2 binds SLIT2 TAS Homo sapiens A0A0G2JZC4 R-RNO-416725 https://reactome.org/PathwayBrowser/#/R-RNO-416725 SEMA6D binds to PLXNA1:TREM2:DAP12 IEA Rattus norvegicus A0A0G2JZE1 R-RNO-141139 https://reactome.org/PathwayBrowser/#/R-RNO-141139 Trimerization of TRAIL:TRAIL receptor complex IEA Rattus norvegicus A0A0G2JZE1 R-RNO-141156 https://reactome.org/PathwayBrowser/#/R-RNO-141156 TRAIL-mediated dimerization of procaspase-8 IEA Rattus norvegicus A0A0G2JZE1 R-RNO-3371359 https://reactome.org/PathwayBrowser/#/R-RNO-3371359 FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling IEA Rattus norvegicus A0A0G2JZE1 R-RNO-3465429 https://reactome.org/PathwayBrowser/#/R-RNO-3465429 FLIP(S) and procaspase-8 form heterodimer IEA Rattus norvegicus A0A0G2JZE1 R-RNO-3465448 https://reactome.org/PathwayBrowser/#/R-RNO-3465448 Caspase-8 and FLIP(L) processing at DISC IEA Rattus norvegicus A0A0G2JZE1 R-RNO-5635741 https://reactome.org/PathwayBrowser/#/R-RNO-5635741 TRAIL receptor-4 binds TRAIL receptor-1 or TRAIL receptor-2 IEA Rattus norvegicus A0A0G2JZE1 R-RNO-5675456 https://reactome.org/PathwayBrowser/#/R-RNO-5675456 FLIP(L) and procaspase-8 form heterodimer IEA Rattus norvegicus A0A0G2JZE1 R-RNO-75146 https://reactome.org/PathwayBrowser/#/R-RNO-75146 TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 IEA Rattus norvegicus A0A0G2JZE1 R-RNO-75187 https://reactome.org/PathwayBrowser/#/R-RNO-75187 TRAIL:TRAIL receptor trimers bind FADD IEA Rattus norvegicus A0A0G2JZE1 R-RNO-75238 https://reactome.org/PathwayBrowser/#/R-RNO-75238 TRAIL binds TRAIL receptors IEA Rattus norvegicus A0A0G2JZF6 R-RNO-6799179 https://reactome.org/PathwayBrowser/#/R-RNO-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Rattus norvegicus A0A0G2JZF6 R-RNO-6799196 https://reactome.org/PathwayBrowser/#/R-RNO-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Rattus norvegicus A0A0G2JZF6 R-RNO-6800870 https://reactome.org/PathwayBrowser/#/R-RNO-6800870 NDUF subunits bind to form the FP subcomplex IEA Rattus norvegicus A0A0G2JZG8 R-RNO-5617816 https://reactome.org/PathwayBrowser/#/R-RNO-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Rattus norvegicus A0A0G2JZG8 R-RNO-5626223 https://reactome.org/PathwayBrowser/#/R-RNO-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Rattus norvegicus A0A0G2JZG8 R-RNO-5626227 https://reactome.org/PathwayBrowser/#/R-RNO-5626227 CP110 and CEP97 dissociate from the centriole IEA Rattus norvegicus A0A0G2JZG8 R-RNO-5626228 https://reactome.org/PathwayBrowser/#/R-RNO-5626228 The distal appendage proteins recruit TTBK2 IEA Rattus norvegicus A0A0G2JZG8 R-RNO-5626681 https://reactome.org/PathwayBrowser/#/R-RNO-5626681 Recruitment of transition zone proteins IEA Rattus norvegicus A0A0G2JZG8 R-RNO-5626699 https://reactome.org/PathwayBrowser/#/R-RNO-5626699 MARK4 binds ODF2 in the centriole IEA Rattus norvegicus A0A0G2JZG8 R-RNO-5638009 https://reactome.org/PathwayBrowser/#/R-RNO-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Rattus norvegicus A0A0G2JZH0 R-RNO-200421 https://reactome.org/PathwayBrowser/#/R-RNO-200421 Activation of cytosolic AMPK by phosphorylation IEA Rattus norvegicus A0A0G2JZH0 R-RNO-380942 https://reactome.org/PathwayBrowser/#/R-RNO-380942 LKB1 forms a trimeric complex with STRAD and MO25 IEA Rattus norvegicus A0A0G2JZH0 R-RNO-6798748 https://reactome.org/PathwayBrowser/#/R-RNO-6798748 Exocytosis of secretory granule lumen proteins IEA Rattus norvegicus A0A0G2JZH0 R-RNO-6800434 https://reactome.org/PathwayBrowser/#/R-RNO-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Rattus norvegicus A0A0G2JZH4 R-RNO-727807 https://reactome.org/PathwayBrowser/#/R-RNO-727807 SLC35A1 exchanges CMP-Neu5Ac for CMP IEA Rattus norvegicus A0A0G2JZJ3 R-RNO-9021287 https://reactome.org/PathwayBrowser/#/R-RNO-9021287 Mecp2 mRNA binds miR-132 RISC TAS Rattus norvegicus A0A0G2JZJ3 R-RNO-9021293 https://reactome.org/PathwayBrowser/#/R-RNO-9021293 Mecp2 mRNA translation is inhibited by miR-132 TAS Rattus norvegicus A0A0G2JZJ3 R-RNO-9615520 https://reactome.org/PathwayBrowser/#/R-RNO-9615520 Mir132 gene expression is stimulated by p-S133-Creb1 TAS Rattus norvegicus A0A0G2JZL1 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus A0A0G2JZL1 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus A0A0G2JZL1 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus A0A0G2JZL1 R-RNO-173626 https://reactome.org/PathwayBrowser/#/R-RNO-173626 Activation of C1r IEA Rattus norvegicus A0A0G2JZL1 R-RNO-173631 https://reactome.org/PathwayBrowser/#/R-RNO-173631 Activation of C1s IEA Rattus norvegicus A0A0G2JZL1 R-RNO-1861621 https://reactome.org/PathwayBrowser/#/R-RNO-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2JZL1 R-RNO-199161 https://reactome.org/PathwayBrowser/#/R-RNO-199161 Fc gamma receptors interact with antigen-bound IgG IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2029268 https://reactome.org/PathwayBrowser/#/R-RNO-2029268 Phosphorylation and activation of PLCG IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2029270 https://reactome.org/PathwayBrowser/#/R-RNO-2029270 Recruitment of PLCgamma to membrane IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2029272 https://reactome.org/PathwayBrowser/#/R-RNO-2029272 Release of PLCG from FCGR IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2029273 https://reactome.org/PathwayBrowser/#/R-RNO-2029273 PI3K binds to p-6Y-SYK IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2029451 https://reactome.org/PathwayBrowser/#/R-RNO-2029451 Activation of RAC1 by VAV IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2029452 https://reactome.org/PathwayBrowser/#/R-RNO-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2029453 https://reactome.org/PathwayBrowser/#/R-RNO-2029453 Phosphorylation of VAV IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2029455 https://reactome.org/PathwayBrowser/#/R-RNO-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2029457 https://reactome.org/PathwayBrowser/#/R-RNO-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2029458 https://reactome.org/PathwayBrowser/#/R-RNO-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2029459 https://reactome.org/PathwayBrowser/#/R-RNO-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2029467 https://reactome.org/PathwayBrowser/#/R-RNO-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2029476 https://reactome.org/PathwayBrowser/#/R-RNO-2029476 Role of myosins in phagosome formation IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2203516 https://reactome.org/PathwayBrowser/#/R-RNO-2203516 Alpha-1-Microglobulin is cleaved IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2454192 https://reactome.org/PathwayBrowser/#/R-RNO-2454192 Allergen dependent IgE bound FCERI aggregation IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2454208 https://reactome.org/PathwayBrowser/#/R-RNO-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2454240 https://reactome.org/PathwayBrowser/#/R-RNO-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2730843 https://reactome.org/PathwayBrowser/#/R-RNO-2730843 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2730851 https://reactome.org/PathwayBrowser/#/R-RNO-2730851 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2730882 https://reactome.org/PathwayBrowser/#/R-RNO-2730882 Phosphorylation of PKC-theta IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2730884 https://reactome.org/PathwayBrowser/#/R-RNO-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Rattus norvegicus A0A0G2JZL1 R-RNO-2730886 https://reactome.org/PathwayBrowser/#/R-RNO-2730886 Phosphorylation of SHC by SYK kinase IEA Rattus norvegicus A0A0G2JZL1 R-RNO-5690701 https://reactome.org/PathwayBrowser/#/R-RNO-5690701 SHP1 binds p-CD22 IEA Rattus norvegicus A0A0G2JZL1 R-RNO-5690702 https://reactome.org/PathwayBrowser/#/R-RNO-5690702 LYN phosphorylates CD22 IEA Rattus norvegicus A0A0G2JZL1 R-RNO-5690740 https://reactome.org/PathwayBrowser/#/R-RNO-5690740 CD22 binds B-cell receptor IEA Rattus norvegicus A0A0G2JZL1 R-RNO-8852266 https://reactome.org/PathwayBrowser/#/R-RNO-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Rattus norvegicus A0A0G2JZL1 R-RNO-8852481 https://reactome.org/PathwayBrowser/#/R-RNO-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Rattus norvegicus A0A0G2JZL1 R-RNO-8858428 https://reactome.org/PathwayBrowser/#/R-RNO-8858428 FCAMR binds IgA IEA Rattus norvegicus A0A0G2JZL1 R-RNO-8858498 https://reactome.org/PathwayBrowser/#/R-RNO-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Rattus norvegicus A0A0G2JZL1 R-RNO-9021306 https://reactome.org/PathwayBrowser/#/R-RNO-9021306 C1-Inh binds and inactivates C1r, C1s IEA Rattus norvegicus A0A0G2JZL1 R-RNO-9606151 https://reactome.org/PathwayBrowser/#/R-RNO-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Rattus norvegicus A0A0G2JZL1 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus A0A0G2JZL1 R-RNO-9724685 https://reactome.org/PathwayBrowser/#/R-RNO-9724685 IgE binds omalizumab IEA Rattus norvegicus A0A0G2JZL1 R-RNO-9725206 https://reactome.org/PathwayBrowser/#/R-RNO-9725206 IgE binds FCERI IEA Rattus norvegicus A0A0G2JZL1 R-RNO-983696 https://reactome.org/PathwayBrowser/#/R-RNO-983696 The Immunoglobulin of the BCR binds antigen IEA Rattus norvegicus A0A0G2JZL1 R-RNO-983700 https://reactome.org/PathwayBrowser/#/R-RNO-983700 SYK binds the activated BCR IEA Rattus norvegicus A0A0G2JZL1 R-RNO-983703 https://reactome.org/PathwayBrowser/#/R-RNO-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Rattus norvegicus A0A0G2JZL1 R-RNO-983707 https://reactome.org/PathwayBrowser/#/R-RNO-983707 SYK autophosphorylates at the activated BCR IEA Rattus norvegicus A0A0G2JZL2 R-RNO-8847875 https://reactome.org/PathwayBrowser/#/R-RNO-8847875 ARF1:GTP binds Golgin TRIP11 IEA Rattus norvegicus A0A0G2JZL2 R-RNO-8940388 https://reactome.org/PathwayBrowser/#/R-RNO-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Rattus norvegicus A0A0G2JZL6 R-RNO-5610725 https://reactome.org/PathwayBrowser/#/R-RNO-5610725 TULP3 is required for GPR161 localization in the cilium IEA Rattus norvegicus A0A0G2JZL6 R-RNO-5610726 https://reactome.org/PathwayBrowser/#/R-RNO-5610726 The IFT-A complex recruits TULP3 IEA Rattus norvegicus A0A0G2JZL6 R-RNO-5610727 https://reactome.org/PathwayBrowser/#/R-RNO-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Rattus norvegicus A0A0G2JZL6 R-RNO-5610766 https://reactome.org/PathwayBrowser/#/R-RNO-5610766 The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base IEA Rattus norvegicus A0A0G2JZL6 R-RNO-5617829 https://reactome.org/PathwayBrowser/#/R-RNO-5617829 Assembly of IFT A complex IEA Rattus norvegicus A0A0G2JZL6 R-RNO-5624949 https://reactome.org/PathwayBrowser/#/R-RNO-5624949 Assembly of the anterograde IFT train IEA Rattus norvegicus A0A0G2JZL6 R-RNO-5624952 https://reactome.org/PathwayBrowser/#/R-RNO-5624952 Assembly of the retrograde IFT train IEA Rattus norvegicus A0A0G2JZL6 R-RNO-5625416 https://reactome.org/PathwayBrowser/#/R-RNO-5625416 Anterograde IFT IEA Rattus norvegicus A0A0G2JZL6 R-RNO-5625421 https://reactome.org/PathwayBrowser/#/R-RNO-5625421 The anterograde IFT train dissociates IEA Rattus norvegicus A0A0G2JZL6 R-RNO-5625424 https://reactome.org/PathwayBrowser/#/R-RNO-5625424 The retrograde IFT train dissociates IEA Rattus norvegicus A0A0G2JZL6 R-RNO-5625426 https://reactome.org/PathwayBrowser/#/R-RNO-5625426 Retrograde IFT IEA Rattus norvegicus A0A0G2JZM4 R-RNO-6805546 https://reactome.org/PathwayBrowser/#/R-RNO-6805546 Keratin type I binds keratin type II IEA Rattus norvegicus A0A0G2JZM4 R-RNO-6805573 https://reactome.org/PathwayBrowser/#/R-RNO-6805573 Keratin type I/type II heterodimers form tetramers IEA Rattus norvegicus A0A0G2JZM4 R-RNO-6806610 https://reactome.org/PathwayBrowser/#/R-RNO-6806610 Keratin filament formation IEA Rattus norvegicus A0A0G2JZM4 R-RNO-6806613 https://reactome.org/PathwayBrowser/#/R-RNO-6806613 Keratin tetramers bind to form unit length filaments IEA Rattus norvegicus A0A0G2JZM4 R-RNO-6806629 https://reactome.org/PathwayBrowser/#/R-RNO-6806629 Formation of tonofilament bundles IEA Rattus norvegicus A0A0G2JZM4 R-RNO-6809393 https://reactome.org/PathwayBrowser/#/R-RNO-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Rattus norvegicus A0A0G2JZM4 R-RNO-6809663 https://reactome.org/PathwayBrowser/#/R-RNO-6809663 Formation of hair keratin fibres IEA Rattus norvegicus A0A0G2JZM4 R-RNO-6810357 https://reactome.org/PathwayBrowser/#/R-RNO-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Rattus norvegicus A0A0G2JZM4 R-RNO-6810937 https://reactome.org/PathwayBrowser/#/R-RNO-6810937 Lamellar bodies bind the early cornified envelope IEA Rattus norvegicus A0A0G2JZM4 R-RNO-6814387 https://reactome.org/PathwayBrowser/#/R-RNO-6814387 CASP14 cleaves filaggrin IEA Rattus norvegicus A0A0G2JZM4 R-RNO-6814734 https://reactome.org/PathwayBrowser/#/R-RNO-6814734 CDSN binds the cornified envelope IEA Rattus norvegicus A0A0G2JZM4 R-RNO-6814764 https://reactome.org/PathwayBrowser/#/R-RNO-6814764 Plasma membrane resorption IEA Rattus norvegicus A0A0G2JZN6 R-RNO-418582 https://reactome.org/PathwayBrowser/#/R-RNO-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Rattus norvegicus A0A0G2JZN6 R-RNO-8982012 https://reactome.org/PathwayBrowser/#/R-RNO-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Rattus norvegicus A0A0G2JZN6 R-RNO-8982017 https://reactome.org/PathwayBrowser/#/R-RNO-8982017 Active G alpha (q) binds RGS proteins IEA Rattus norvegicus A0A0G2JZN6 R-RNO-8982019 https://reactome.org/PathwayBrowser/#/R-RNO-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Rattus norvegicus A0A0G2JZN6 R-RNO-8982020 https://reactome.org/PathwayBrowser/#/R-RNO-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Rattus norvegicus A0A0G2JZN6 R-RNO-8982025 https://reactome.org/PathwayBrowser/#/R-RNO-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Rattus norvegicus A0A0G2JZN6 R-RNO-8982026 https://reactome.org/PathwayBrowser/#/R-RNO-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Rattus norvegicus A0A0G2JZW2 R-RNO-2990840 https://reactome.org/PathwayBrowser/#/R-RNO-2990840 SENP1,2,5 proteolytically process SUMO1 IEA Rattus norvegicus A0A0G2JZW2 R-RNO-2990842 https://reactome.org/PathwayBrowser/#/R-RNO-2990842 SENP1,2,5 proteolytically process SUMO2 IEA Rattus norvegicus A0A0G2JZW2 R-RNO-2993763 https://reactome.org/PathwayBrowser/#/R-RNO-2993763 SENP1,2,5 proteolytically process SUMO3 IEA Rattus norvegicus A0A0G2K001 R-RNO-5159245 https://reactome.org/PathwayBrowser/#/R-RNO-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Rattus norvegicus A0A0G2K001 R-RNO-5637686 https://reactome.org/PathwayBrowser/#/R-RNO-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Rattus norvegicus A0A0G2K001 R-RNO-5638333 https://reactome.org/PathwayBrowser/#/R-RNO-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Rattus norvegicus A0A0G2K001 R-RNO-5649800 https://reactome.org/PathwayBrowser/#/R-RNO-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Rattus norvegicus A0A0G2K001 R-RNO-5649802 https://reactome.org/PathwayBrowser/#/R-RNO-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Rattus norvegicus A0A0G2K008 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2K047 R-RNO-8875071 https://reactome.org/PathwayBrowser/#/R-RNO-8875071 ACSS3 ligates CoA to CH3COO- IEA Rattus norvegicus A0A0G2K048 R-RNO-1912357 https://reactome.org/PathwayBrowser/#/R-RNO-1912357 ITCH ubiquitinates DTX IEA Rattus norvegicus A0A0G2K048 R-RNO-1980125 https://reactome.org/PathwayBrowser/#/R-RNO-1980125 ITCH binds DTX IEA Rattus norvegicus A0A0G2K048 R-RNO-2396007 https://reactome.org/PathwayBrowser/#/R-RNO-2396007 IRF3 is phosphorylated by TBK1 IEA Rattus norvegicus A0A0G2K048 R-RNO-3249392 https://reactome.org/PathwayBrowser/#/R-RNO-3249392 NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3 IEA Rattus norvegicus A0A0G2K048 R-RNO-8948709 https://reactome.org/PathwayBrowser/#/R-RNO-8948709 DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 IEA Rattus norvegicus A0A0G2K049 R-RNO-9932443 https://reactome.org/PathwayBrowser/#/R-RNO-9932443 BICRA, BICRAL and BRD9 bind SMARCC dimer:SMARCDs IEA Rattus norvegicus A0A0G2K049 R-RNO-9933236 https://reactome.org/PathwayBrowser/#/R-RNO-9933236 SS18-containing ATPase complex binds SMARCC dimer:SMARCDs:BICRAs:BRD9 IEA Rattus norvegicus A0A0G2K059 R-RNO-8949178 https://reactome.org/PathwayBrowser/#/R-RNO-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix IEA Rattus norvegicus A0A0G2K059 R-RNO-8953461 https://reactome.org/PathwayBrowser/#/R-RNO-8953461 SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex IEA Rattus norvegicus A0A0G2K066 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus A0A0G2K066 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus A0A0G2K066 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus A0A0G2K066 R-RNO-173626 https://reactome.org/PathwayBrowser/#/R-RNO-173626 Activation of C1r IEA Rattus norvegicus A0A0G2K066 R-RNO-173631 https://reactome.org/PathwayBrowser/#/R-RNO-173631 Activation of C1s IEA Rattus norvegicus A0A0G2K066 R-RNO-1861621 https://reactome.org/PathwayBrowser/#/R-RNO-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K066 R-RNO-199161 https://reactome.org/PathwayBrowser/#/R-RNO-199161 Fc gamma receptors interact with antigen-bound IgG IEA Rattus norvegicus A0A0G2K066 R-RNO-2029268 https://reactome.org/PathwayBrowser/#/R-RNO-2029268 Phosphorylation and activation of PLCG IEA Rattus norvegicus A0A0G2K066 R-RNO-2029270 https://reactome.org/PathwayBrowser/#/R-RNO-2029270 Recruitment of PLCgamma to membrane IEA Rattus norvegicus A0A0G2K066 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K066 R-RNO-2029272 https://reactome.org/PathwayBrowser/#/R-RNO-2029272 Release of PLCG from FCGR IEA Rattus norvegicus A0A0G2K066 R-RNO-2029273 https://reactome.org/PathwayBrowser/#/R-RNO-2029273 PI3K binds to p-6Y-SYK IEA Rattus norvegicus A0A0G2K066 R-RNO-2029451 https://reactome.org/PathwayBrowser/#/R-RNO-2029451 Activation of RAC1 by VAV IEA Rattus norvegicus A0A0G2K066 R-RNO-2029452 https://reactome.org/PathwayBrowser/#/R-RNO-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Rattus norvegicus A0A0G2K066 R-RNO-2029453 https://reactome.org/PathwayBrowser/#/R-RNO-2029453 Phosphorylation of VAV IEA Rattus norvegicus A0A0G2K066 R-RNO-2029455 https://reactome.org/PathwayBrowser/#/R-RNO-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K066 R-RNO-2029457 https://reactome.org/PathwayBrowser/#/R-RNO-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K066 R-RNO-2029458 https://reactome.org/PathwayBrowser/#/R-RNO-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Rattus norvegicus A0A0G2K066 R-RNO-2029459 https://reactome.org/PathwayBrowser/#/R-RNO-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Rattus norvegicus A0A0G2K066 R-RNO-2029467 https://reactome.org/PathwayBrowser/#/R-RNO-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Rattus norvegicus A0A0G2K066 R-RNO-2029476 https://reactome.org/PathwayBrowser/#/R-RNO-2029476 Role of myosins in phagosome formation IEA Rattus norvegicus A0A0G2K066 R-RNO-2203516 https://reactome.org/PathwayBrowser/#/R-RNO-2203516 Alpha-1-Microglobulin is cleaved IEA Rattus norvegicus A0A0G2K066 R-RNO-2454192 https://reactome.org/PathwayBrowser/#/R-RNO-2454192 Allergen dependent IgE bound FCERI aggregation IEA Rattus norvegicus A0A0G2K066 R-RNO-2454208 https://reactome.org/PathwayBrowser/#/R-RNO-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Rattus norvegicus A0A0G2K066 R-RNO-2454240 https://reactome.org/PathwayBrowser/#/R-RNO-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Rattus norvegicus A0A0G2K066 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus A0A0G2K066 R-RNO-2730843 https://reactome.org/PathwayBrowser/#/R-RNO-2730843 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus A0A0G2K066 R-RNO-2730851 https://reactome.org/PathwayBrowser/#/R-RNO-2730851 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus A0A0G2K066 R-RNO-2730882 https://reactome.org/PathwayBrowser/#/R-RNO-2730882 Phosphorylation of PKC-theta IEA Rattus norvegicus A0A0G2K066 R-RNO-2730884 https://reactome.org/PathwayBrowser/#/R-RNO-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Rattus norvegicus A0A0G2K066 R-RNO-2730886 https://reactome.org/PathwayBrowser/#/R-RNO-2730886 Phosphorylation of SHC by SYK kinase IEA Rattus norvegicus A0A0G2K066 R-RNO-5690701 https://reactome.org/PathwayBrowser/#/R-RNO-5690701 SHP1 binds p-CD22 IEA Rattus norvegicus A0A0G2K066 R-RNO-5690702 https://reactome.org/PathwayBrowser/#/R-RNO-5690702 LYN phosphorylates CD22 IEA Rattus norvegicus A0A0G2K066 R-RNO-5690740 https://reactome.org/PathwayBrowser/#/R-RNO-5690740 CD22 binds B-cell receptor IEA Rattus norvegicus A0A0G2K066 R-RNO-8852266 https://reactome.org/PathwayBrowser/#/R-RNO-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Rattus norvegicus A0A0G2K066 R-RNO-8852481 https://reactome.org/PathwayBrowser/#/R-RNO-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Rattus norvegicus A0A0G2K066 R-RNO-8858428 https://reactome.org/PathwayBrowser/#/R-RNO-8858428 FCAMR binds IgA IEA Rattus norvegicus A0A0G2K066 R-RNO-9021306 https://reactome.org/PathwayBrowser/#/R-RNO-9021306 C1-Inh binds and inactivates C1r, C1s IEA Rattus norvegicus A0A0G2K066 R-RNO-9606151 https://reactome.org/PathwayBrowser/#/R-RNO-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Rattus norvegicus A0A0G2K066 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus A0A0G2K066 R-RNO-9724685 https://reactome.org/PathwayBrowser/#/R-RNO-9724685 IgE binds omalizumab IEA Rattus norvegicus A0A0G2K066 R-RNO-9725206 https://reactome.org/PathwayBrowser/#/R-RNO-9725206 IgE binds FCERI IEA Rattus norvegicus A0A0G2K066 R-RNO-983696 https://reactome.org/PathwayBrowser/#/R-RNO-983696 The Immunoglobulin of the BCR binds antigen IEA Rattus norvegicus A0A0G2K066 R-RNO-983700 https://reactome.org/PathwayBrowser/#/R-RNO-983700 SYK binds the activated BCR IEA Rattus norvegicus A0A0G2K066 R-RNO-983703 https://reactome.org/PathwayBrowser/#/R-RNO-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Rattus norvegicus A0A0G2K066 R-RNO-983707 https://reactome.org/PathwayBrowser/#/R-RNO-983707 SYK autophosphorylates at the activated BCR IEA Rattus norvegicus A0A0G2K068 R-RNO-202703 https://reactome.org/PathwayBrowser/#/R-RNO-202703 CD47 binds SIRP IEA Rattus norvegicus A0A0G2K068 R-RNO-391168 https://reactome.org/PathwayBrowser/#/R-RNO-391168 SIRP gamma binds CD47 IEA Rattus norvegicus A0A0G2K069 R-RNO-1454757 https://reactome.org/PathwayBrowser/#/R-RNO-1454757 Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 IEA Rattus norvegicus A0A0G2K069 R-RNO-1474266 https://reactome.org/PathwayBrowser/#/R-RNO-1474266 Formation of collagen fibrils IEA Rattus norvegicus A0A0G2K069 R-RNO-1650808 https://reactome.org/PathwayBrowser/#/R-RNO-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Rattus norvegicus A0A0G2K069 R-RNO-1980233 https://reactome.org/PathwayBrowser/#/R-RNO-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Rattus norvegicus A0A0G2K069 R-RNO-1981104 https://reactome.org/PathwayBrowser/#/R-RNO-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Rattus norvegicus A0A0G2K069 R-RNO-1981120 https://reactome.org/PathwayBrowser/#/R-RNO-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Rattus norvegicus A0A0G2K069 R-RNO-1981128 https://reactome.org/PathwayBrowser/#/R-RNO-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Rattus norvegicus A0A0G2K069 R-RNO-1981157 https://reactome.org/PathwayBrowser/#/R-RNO-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Rattus norvegicus A0A0G2K069 R-RNO-2002428 https://reactome.org/PathwayBrowser/#/R-RNO-2002428 Removal of fibrillar collagen N-propeptides IEA Rattus norvegicus A0A0G2K069 R-RNO-2002440 https://reactome.org/PathwayBrowser/#/R-RNO-2002440 Removal of fibrillar collagen C-propeptides IEA Rattus norvegicus A0A0G2K069 R-RNO-2002460 https://reactome.org/PathwayBrowser/#/R-RNO-2002460 P4HB binds Collagen chains IEA Rattus norvegicus A0A0G2K069 R-RNO-2089971 https://reactome.org/PathwayBrowser/#/R-RNO-2089971 Secretion of collagens IEA Rattus norvegicus A0A0G2K069 R-RNO-2213201 https://reactome.org/PathwayBrowser/#/R-RNO-2213201 Formation of collagen fibres IEA Rattus norvegicus A0A0G2K069 R-RNO-2299620 https://reactome.org/PathwayBrowser/#/R-RNO-2299620 Collagen XI cross-links with collagen II IEA Rattus norvegicus A0A0G2K069 R-RNO-2327738 https://reactome.org/PathwayBrowser/#/R-RNO-2327738 DDR1 binds collagen type I, II, III, IV, V, XI fibrils IEA Rattus norvegicus A0A0G2K069 R-RNO-8874079 https://reactome.org/PathwayBrowser/#/R-RNO-8874079 PTK2 binds activated MET IEA Rattus norvegicus A0A0G2K069 R-RNO-8944266 https://reactome.org/PathwayBrowser/#/R-RNO-8944266 Association of procollagen type XI IEA Rattus norvegicus A0A0G2K069 R-RNO-8948219 https://reactome.org/PathwayBrowser/#/R-RNO-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus A0A0G2K069 R-RNO-8948222 https://reactome.org/PathwayBrowser/#/R-RNO-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K069 R-RNO-8948224 https://reactome.org/PathwayBrowser/#/R-RNO-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K069 R-RNO-8948228 https://reactome.org/PathwayBrowser/#/R-RNO-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus A0A0G2K069 R-RNO-8948231 https://reactome.org/PathwayBrowser/#/R-RNO-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K069 R-RNO-8948232 https://reactome.org/PathwayBrowser/#/R-RNO-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Rattus norvegicus A0A0G2K069 R-RNO-8948234 https://reactome.org/PathwayBrowser/#/R-RNO-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K089 R-RNO-8876188 https://reactome.org/PathwayBrowser/#/R-RNO-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Rattus norvegicus A0A0G2K094 R-RNO-9679787 https://reactome.org/PathwayBrowser/#/R-RNO-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Rattus norvegicus A0A0G2K0A0 R-RNO-8847880 https://reactome.org/PathwayBrowser/#/R-RNO-8847880 CYTH proteins bind ARF1:GTP IEA Rattus norvegicus A0A0G2K0A0 R-RNO-8847883 https://reactome.org/PathwayBrowser/#/R-RNO-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Rattus norvegicus A0A0G2K0C0 R-RNO-6787533 https://reactome.org/PathwayBrowser/#/R-RNO-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Rattus norvegicus A0A0G2K0D3 R-RNO-445700 https://reactome.org/PathwayBrowser/#/R-RNO-445700 Myosin Binds ATP IEA Rattus norvegicus A0A0G2K0D3 R-RNO-445704 https://reactome.org/PathwayBrowser/#/R-RNO-445704 Calcium Binds Caldesmon IEA Rattus norvegicus A0A0G2K0D3 R-RNO-445705 https://reactome.org/PathwayBrowser/#/R-RNO-445705 Release Of ADP From Myosin IEA Rattus norvegicus A0A0G2K0E7 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2K0E7 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus A0A0G2K0E7 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2K0E7 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2K0G9 R-RNO-8875320 https://reactome.org/PathwayBrowser/#/R-RNO-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Rattus norvegicus A0A0G2K0G9 R-RNO-8877311 https://reactome.org/PathwayBrowser/#/R-RNO-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 IEA Rattus norvegicus A0A0G2K0H3 R-RNO-1504186 https://reactome.org/PathwayBrowser/#/R-RNO-1504186 DVL recruits GSK3beta:AXIN1 to the receptor complex IEA Rattus norvegicus A0A0G2K0H3 R-RNO-201677 https://reactome.org/PathwayBrowser/#/R-RNO-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Rattus norvegicus A0A0G2K0H3 R-RNO-201685 https://reactome.org/PathwayBrowser/#/R-RNO-201685 Beta-catenin is released from the destruction complex IEA Rattus norvegicus A0A0G2K0H3 R-RNO-3769397 https://reactome.org/PathwayBrowser/#/R-RNO-3769397 SOST binds LRP5/6 IEA Rattus norvegicus A0A0G2K0H3 R-RNO-3769401 https://reactome.org/PathwayBrowser/#/R-RNO-3769401 DKK and KRM bind LRP5/6 IEA Rattus norvegicus A0A0G2K0H3 R-RNO-4641236 https://reactome.org/PathwayBrowser/#/R-RNO-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Rattus norvegicus A0A0G2K0H3 R-RNO-4641249 https://reactome.org/PathwayBrowser/#/R-RNO-4641249 ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex IEA Rattus norvegicus A0A0G2K0H3 R-RNO-4641253 https://reactome.org/PathwayBrowser/#/R-RNO-4641253 ZNRF3 ubiquitinates FZD to promote its downregulation IEA Rattus norvegicus A0A0G2K0H3 R-RNO-5368586 https://reactome.org/PathwayBrowser/#/R-RNO-5368586 DKK promotes clathrin-dependent internalization of LRP6 IEA Rattus norvegicus A0A0G2K0H3 R-RNO-5368596 https://reactome.org/PathwayBrowser/#/R-RNO-5368596 WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 IEA Rattus norvegicus A0A0G2K0I0 R-RNO-2684901 https://reactome.org/PathwayBrowser/#/R-RNO-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Rattus norvegicus A0A0G2K0I4 R-RNO-6805546 https://reactome.org/PathwayBrowser/#/R-RNO-6805546 Keratin type I binds keratin type II IEA Rattus norvegicus A0A0G2K0I4 R-RNO-6805573 https://reactome.org/PathwayBrowser/#/R-RNO-6805573 Keratin type I/type II heterodimers form tetramers IEA Rattus norvegicus A0A0G2K0I4 R-RNO-6806610 https://reactome.org/PathwayBrowser/#/R-RNO-6806610 Keratin filament formation IEA Rattus norvegicus A0A0G2K0I4 R-RNO-6806613 https://reactome.org/PathwayBrowser/#/R-RNO-6806613 Keratin tetramers bind to form unit length filaments IEA Rattus norvegicus A0A0G2K0I4 R-RNO-6806629 https://reactome.org/PathwayBrowser/#/R-RNO-6806629 Formation of tonofilament bundles IEA Rattus norvegicus A0A0G2K0I4 R-RNO-6809393 https://reactome.org/PathwayBrowser/#/R-RNO-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Rattus norvegicus A0A0G2K0I4 R-RNO-6809663 https://reactome.org/PathwayBrowser/#/R-RNO-6809663 Formation of hair keratin fibres IEA Rattus norvegicus A0A0G2K0I4 R-RNO-6810357 https://reactome.org/PathwayBrowser/#/R-RNO-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Rattus norvegicus A0A0G2K0I4 R-RNO-6810937 https://reactome.org/PathwayBrowser/#/R-RNO-6810937 Lamellar bodies bind the early cornified envelope IEA Rattus norvegicus A0A0G2K0I4 R-RNO-6814387 https://reactome.org/PathwayBrowser/#/R-RNO-6814387 CASP14 cleaves filaggrin IEA Rattus norvegicus A0A0G2K0I4 R-RNO-6814734 https://reactome.org/PathwayBrowser/#/R-RNO-6814734 CDSN binds the cornified envelope IEA Rattus norvegicus A0A0G2K0I4 R-RNO-6814764 https://reactome.org/PathwayBrowser/#/R-RNO-6814764 Plasma membrane resorption IEA Rattus norvegicus A0A0G2K0I6 R-RNO-419001 https://reactome.org/PathwayBrowser/#/R-RNO-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Rattus norvegicus A0A0G2K0I6 R-RNO-5357477 https://reactome.org/PathwayBrowser/#/R-RNO-5357477 PAK1-3 phosphorylates VE-cadherin IEA Rattus norvegicus A0A0G2K0J0 R-RNO-112379 https://reactome.org/PathwayBrowser/#/R-RNO-112379 Recruitment of elongation factors to form elongation complex IEA Rattus norvegicus A0A0G2K0J0 R-RNO-112385 https://reactome.org/PathwayBrowser/#/R-RNO-112385 Addition of nucleotides leads to transcript elongation IEA Rattus norvegicus A0A0G2K0J0 R-RNO-112392 https://reactome.org/PathwayBrowser/#/R-RNO-112392 Resumption of elongation after recovery from pausing IEA Rattus norvegicus A0A0G2K0J0 R-RNO-112395 https://reactome.org/PathwayBrowser/#/R-RNO-112395 Abortive termination of elongation after arrest IEA Rattus norvegicus A0A0G2K0J0 R-RNO-112396 https://reactome.org/PathwayBrowser/#/R-RNO-112396 Separation of elongating transcript from template IEA Rattus norvegicus A0A0G2K0J0 R-RNO-113411 https://reactome.org/PathwayBrowser/#/R-RNO-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Rattus norvegicus A0A0G2K0J0 R-RNO-113412 https://reactome.org/PathwayBrowser/#/R-RNO-113412 Pol II elongation complex moves on the template as transcript elongates IEA Rattus norvegicus A0A0G2K0J0 R-RNO-113413 https://reactome.org/PathwayBrowser/#/R-RNO-113413 TFIIS-mediated recovery of elongation from arrest IEA Rattus norvegicus A0A0G2K0J0 R-RNO-113414 https://reactome.org/PathwayBrowser/#/R-RNO-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Rattus norvegicus A0A0G2K0J0 R-RNO-113429 https://reactome.org/PathwayBrowser/#/R-RNO-113429 Elongating transcript encounters a lesion in the template IEA Rattus norvegicus A0A0G2K0J7 R-RNO-112379 https://reactome.org/PathwayBrowser/#/R-RNO-112379 Recruitment of elongation factors to form elongation complex IEA Rattus norvegicus A0A0G2K0J7 R-RNO-112381 https://reactome.org/PathwayBrowser/#/R-RNO-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Rattus norvegicus A0A0G2K0J7 R-RNO-112383 https://reactome.org/PathwayBrowser/#/R-RNO-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Rattus norvegicus A0A0G2K0J7 R-RNO-112385 https://reactome.org/PathwayBrowser/#/R-RNO-112385 Addition of nucleotides leads to transcript elongation IEA Rattus norvegicus A0A0G2K0J7 R-RNO-112392 https://reactome.org/PathwayBrowser/#/R-RNO-112392 Resumption of elongation after recovery from pausing IEA Rattus norvegicus A0A0G2K0J7 R-RNO-112395 https://reactome.org/PathwayBrowser/#/R-RNO-112395 Abortive termination of elongation after arrest IEA Rattus norvegicus A0A0G2K0J7 R-RNO-112396 https://reactome.org/PathwayBrowser/#/R-RNO-112396 Separation of elongating transcript from template IEA Rattus norvegicus A0A0G2K0J7 R-RNO-113402 https://reactome.org/PathwayBrowser/#/R-RNO-113402 Formation of DSIF:NELF:early elongation complex IEA Rattus norvegicus A0A0G2K0J7 R-RNO-113407 https://reactome.org/PathwayBrowser/#/R-RNO-113407 DSIF complex binds to RNA Pol II (hypophosphorylated) IEA Rattus norvegicus A0A0G2K0J7 R-RNO-113409 https://reactome.org/PathwayBrowser/#/R-RNO-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Rattus norvegicus A0A0G2K0J7 R-RNO-113411 https://reactome.org/PathwayBrowser/#/R-RNO-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Rattus norvegicus A0A0G2K0J7 R-RNO-113412 https://reactome.org/PathwayBrowser/#/R-RNO-113412 Pol II elongation complex moves on the template as transcript elongates IEA Rattus norvegicus A0A0G2K0J7 R-RNO-113413 https://reactome.org/PathwayBrowser/#/R-RNO-113413 TFIIS-mediated recovery of elongation from arrest IEA Rattus norvegicus A0A0G2K0J7 R-RNO-113414 https://reactome.org/PathwayBrowser/#/R-RNO-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Rattus norvegicus A0A0G2K0J7 R-RNO-113429 https://reactome.org/PathwayBrowser/#/R-RNO-113429 Elongating transcript encounters a lesion in the template IEA Rattus norvegicus A0A0G2K0J7 R-RNO-6797606 https://reactome.org/PathwayBrowser/#/R-RNO-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Rattus norvegicus A0A0G2K0J7 R-RNO-6797616 https://reactome.org/PathwayBrowser/#/R-RNO-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Rattus norvegicus A0A0G2K0K3 R-RNO-9639287 https://reactome.org/PathwayBrowser/#/R-RNO-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Rattus norvegicus A0A0G2K0K3 R-RNO-9640195 https://reactome.org/PathwayBrowser/#/R-RNO-9640195 RRAGA,B hydrolyzes GTP IEA Rattus norvegicus A0A0G2K0K3 R-RNO-9640237 https://reactome.org/PathwayBrowser/#/R-RNO-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Rattus norvegicus A0A0G2K0K3 R-RNO-9640254 https://reactome.org/PathwayBrowser/#/R-RNO-9640254 BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 IEA Rattus norvegicus A0A0G2K0K3 R-RNO-9657619 https://reactome.org/PathwayBrowser/#/R-RNO-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 IEA Rattus norvegicus A0A0G2K0L0 R-RNO-174389 https://reactome.org/PathwayBrowser/#/R-RNO-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Rattus norvegicus A0A0G2K0L0 R-RNO-174392 https://reactome.org/PathwayBrowser/#/R-RNO-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Rattus norvegicus A0A0G2K0P1 R-RNO-2213248 https://reactome.org/PathwayBrowser/#/R-RNO-2213248 Transport of antigen loaded MHC II molecules to surface IEA Rattus norvegicus A0A0G2K0P1 R-RNO-5624949 https://reactome.org/PathwayBrowser/#/R-RNO-5624949 Assembly of the anterograde IFT train IEA Rattus norvegicus A0A0G2K0P1 R-RNO-5624952 https://reactome.org/PathwayBrowser/#/R-RNO-5624952 Assembly of the retrograde IFT train IEA Rattus norvegicus A0A0G2K0P1 R-RNO-5625416 https://reactome.org/PathwayBrowser/#/R-RNO-5625416 Anterograde IFT IEA Rattus norvegicus A0A0G2K0P1 R-RNO-5625421 https://reactome.org/PathwayBrowser/#/R-RNO-5625421 The anterograde IFT train dissociates IEA Rattus norvegicus A0A0G2K0P1 R-RNO-5625424 https://reactome.org/PathwayBrowser/#/R-RNO-5625424 The retrograde IFT train dissociates IEA Rattus norvegicus A0A0G2K0P1 R-RNO-5625426 https://reactome.org/PathwayBrowser/#/R-RNO-5625426 Retrograde IFT IEA Rattus norvegicus A0A0G2K0P1 R-RNO-6811423 https://reactome.org/PathwayBrowser/#/R-RNO-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Rattus norvegicus A0A0G2K0P1 R-RNO-6811426 https://reactome.org/PathwayBrowser/#/R-RNO-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Rattus norvegicus A0A0G2K0P1 R-RNO-983259 https://reactome.org/PathwayBrowser/#/R-RNO-983259 Kinesins move along microtubules consuming ATP IEA Rattus norvegicus A0A0G2K0P1 R-RNO-983266 https://reactome.org/PathwayBrowser/#/R-RNO-983266 Kinesins bind microtubules IEA Rattus norvegicus A0A0G2K0R0 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2K0V1 R-RNO-6814549 https://reactome.org/PathwayBrowser/#/R-RNO-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Rattus norvegicus A0A0G2K0V1 R-RNO-6814555 https://reactome.org/PathwayBrowser/#/R-RNO-6814555 Integrator complex processes the 3' end of snRNA IEA Rattus norvegicus A0A0G2K0V1 R-RNO-6814559 https://reactome.org/PathwayBrowser/#/R-RNO-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Rattus norvegicus A0A0G2K0V1 R-RNO-6814885 https://reactome.org/PathwayBrowser/#/R-RNO-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Rattus norvegicus A0A0G2K0V6 R-RNO-187937 https://reactome.org/PathwayBrowser/#/R-RNO-187937 Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 IEA Rattus norvegicus A0A0G2K0V6 R-RNO-187959 https://reactome.org/PathwayBrowser/#/R-RNO-187959 Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) IEA Rattus norvegicus A0A0G2K0V6 R-RNO-9018017 https://reactome.org/PathwayBrowser/#/R-RNO-9018017 RB1 binds and inhibits E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus A0A0G2K0W3 R-RNO-2744242 https://reactome.org/PathwayBrowser/#/R-RNO-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Rattus norvegicus A0A0G2K0X0 R-RNO-1482781 https://reactome.org/PathwayBrowser/#/R-RNO-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Rattus norvegicus A0A0G2K0X0 R-RNO-1482794 https://reactome.org/PathwayBrowser/#/R-RNO-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Rattus norvegicus A0A0G2K0X0 R-RNO-1482850 https://reactome.org/PathwayBrowser/#/R-RNO-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Rattus norvegicus A0A0G2K0X0 R-RNO-1482894 https://reactome.org/PathwayBrowser/#/R-RNO-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Rattus norvegicus A0A0G2K0Z9 R-RNO-6791221 https://reactome.org/PathwayBrowser/#/R-RNO-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA IEA Rattus norvegicus A0A0G2K0Z9 R-RNO-6791222 https://reactome.org/PathwayBrowser/#/R-RNO-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Rattus norvegicus A0A0G2K0Z9 R-RNO-6791227 https://reactome.org/PathwayBrowser/#/R-RNO-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Rattus norvegicus A0A0G2K109 R-RNO-3299569 https://reactome.org/PathwayBrowser/#/R-RNO-3299569 Beta-catenin displaces TLE:HDAC1 from TCF/LEF IEA Rattus norvegicus A0A0G2K109 R-RNO-3322429 https://reactome.org/PathwayBrowser/#/R-RNO-3322429 XIAP monoubiquinates TLE IEA Rattus norvegicus A0A0G2K109 R-RNO-3322431 https://reactome.org/PathwayBrowser/#/R-RNO-3322431 XIAP binds TLE IEA Rattus norvegicus A0A0G2K109 R-RNO-3322434 https://reactome.org/PathwayBrowser/#/R-RNO-3322434 XIAP dissociates from ub-TLE IEA Rattus norvegicus A0A0G2K109 R-RNO-3361751 https://reactome.org/PathwayBrowser/#/R-RNO-3361751 beta-catenin is replaced by repression complexes at the promoter IEA Rattus norvegicus A0A0G2K109 R-RNO-4641229 https://reactome.org/PathwayBrowser/#/R-RNO-4641229 TLE oligomerizes IEA Rattus norvegicus A0A0G2K109 R-RNO-8944349 https://reactome.org/PathwayBrowser/#/R-RNO-8944349 TLE tetramers bind TCF/LEF at WNT promoters IEA Rattus norvegicus A0A0G2K112 R-RNO-203973 https://reactome.org/PathwayBrowser/#/R-RNO-203973 Vesicle budding IEA Rattus norvegicus A0A0G2K112 R-RNO-204008 https://reactome.org/PathwayBrowser/#/R-RNO-204008 SEC31:SEC13 and v-SNARE recruitment IEA Rattus norvegicus A0A0G2K112 R-RNO-5694409 https://reactome.org/PathwayBrowser/#/R-RNO-5694409 Nucleotide exchange on RAB1 IEA Rattus norvegicus A0A0G2K112 R-RNO-5694417 https://reactome.org/PathwayBrowser/#/R-RNO-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Rattus norvegicus A0A0G2K112 R-RNO-5694418 https://reactome.org/PathwayBrowser/#/R-RNO-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Rattus norvegicus A0A0G2K112 R-RNO-5694439 https://reactome.org/PathwayBrowser/#/R-RNO-5694439 COPII coat binds TRAPPCII and RAB1:GDP IEA Rattus norvegicus A0A0G2K112 R-RNO-5694441 https://reactome.org/PathwayBrowser/#/R-RNO-5694441 CSNK1D phosphorylates SEC23 IEA Rattus norvegicus A0A0G2K112 R-RNO-5694445 https://reactome.org/PathwayBrowser/#/R-RNO-5694445 CNIH1 binds TFGA and AREG precursors IEA Rattus norvegicus A0A0G2K112 R-RNO-5694446 https://reactome.org/PathwayBrowser/#/R-RNO-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Rattus norvegicus A0A0G2K112 R-RNO-5694522 https://reactome.org/PathwayBrowser/#/R-RNO-5694522 Inner coat assembly and cargo binding IEA Rattus norvegicus A0A0G2K112 R-RNO-5694527 https://reactome.org/PathwayBrowser/#/R-RNO-5694527 Loss of SAR1B GTPase IEA Rattus norvegicus A0A0G2K130 R-RNO-166245 https://reactome.org/PathwayBrowser/#/R-RNO-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Rattus norvegicus A0A0G2K130 R-RNO-166271 https://reactome.org/PathwayBrowser/#/R-RNO-166271 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 IEA Rattus norvegicus A0A0G2K130 R-RNO-5362486 https://reactome.org/PathwayBrowser/#/R-RNO-5362486 TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4 IEA Rattus norvegicus A0A0G2K130 R-RNO-5362500 https://reactome.org/PathwayBrowser/#/R-RNO-5362500 TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Rattus norvegicus A0A0G2K130 R-RNO-9823904 https://reactome.org/PathwayBrowser/#/R-RNO-9823904 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Rattus norvegicus A0A0G2K130 R-RNO-9823906 https://reactome.org/PathwayBrowser/#/R-RNO-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Rattus norvegicus A0A0G2K130 R-RNO-9823910 https://reactome.org/PathwayBrowser/#/R-RNO-9823910 Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Rattus norvegicus A0A0G2K130 R-RNO-9823932 https://reactome.org/PathwayBrowser/#/R-RNO-9823932 Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Rattus norvegicus A0A0G2K130 R-RNO-9823934 https://reactome.org/PathwayBrowser/#/R-RNO-9823934 OPTN binds TBK1 within the activated TLR4 complex IEA Rattus norvegicus A0A0G2K130 R-RNO-9823939 https://reactome.org/PathwayBrowser/#/R-RNO-9823939 IKKε (IKBKE) is ubiquitinated within the activated TLR4 IEA Rattus norvegicus A0A0G2K130 R-RNO-9824882 https://reactome.org/PathwayBrowser/#/R-RNO-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Rattus norvegicus A0A0G2K160 R-RNO-141409 https://reactome.org/PathwayBrowser/#/R-RNO-141409 Mad1 binds kinetochore IEA Rattus norvegicus A0A0G2K160 R-RNO-141422 https://reactome.org/PathwayBrowser/#/R-RNO-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Rattus norvegicus A0A0G2K160 R-RNO-141431 https://reactome.org/PathwayBrowser/#/R-RNO-141431 MAD2 associates with the Mad1 kinetochore complex IEA Rattus norvegicus A0A0G2K160 R-RNO-141439 https://reactome.org/PathwayBrowser/#/R-RNO-141439 Release of activated MAD2 from kinetochores IEA Rattus norvegicus A0A0G2K160 R-RNO-1638803 https://reactome.org/PathwayBrowser/#/R-RNO-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Rattus norvegicus A0A0G2K160 R-RNO-1638821 https://reactome.org/PathwayBrowser/#/R-RNO-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Rattus norvegicus A0A0G2K160 R-RNO-2467809 https://reactome.org/PathwayBrowser/#/R-RNO-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Rattus norvegicus A0A0G2K160 R-RNO-2467811 https://reactome.org/PathwayBrowser/#/R-RNO-2467811 Separation of sister chromatids IEA Rattus norvegicus A0A0G2K160 R-RNO-2468287 https://reactome.org/PathwayBrowser/#/R-RNO-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Rattus norvegicus A0A0G2K160 R-RNO-2484822 https://reactome.org/PathwayBrowser/#/R-RNO-2484822 Kinetochore assembly IEA Rattus norvegicus A0A0G2K160 R-RNO-375302 https://reactome.org/PathwayBrowser/#/R-RNO-375302 Kinetochore capture of astral microtubules IEA Rattus norvegicus A0A0G2K160 R-RNO-5666129 https://reactome.org/PathwayBrowser/#/R-RNO-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Rattus norvegicus A0A0G2K160 R-RNO-5666160 https://reactome.org/PathwayBrowser/#/R-RNO-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Rattus norvegicus A0A0G2K160 R-RNO-5666169 https://reactome.org/PathwayBrowser/#/R-RNO-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Rattus norvegicus A0A0G2K160 R-RNO-9615901 https://reactome.org/PathwayBrowser/#/R-RNO-9615901 AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex IEA Rattus norvegicus A0A0G2K160 R-RNO-9618378 https://reactome.org/PathwayBrowser/#/R-RNO-9618378 POM121 binds the Nup107-Nup160 complex IEA Rattus norvegicus A0A0G2K160 R-RNO-9634169 https://reactome.org/PathwayBrowser/#/R-RNO-9634169 POM121 and NDC1 bind the Nup93 complex IEA Rattus norvegicus A0A0G2K160 R-RNO-9648114 https://reactome.org/PathwayBrowser/#/R-RNO-9648114 EML4 recruits NUDC to mitotic spindle IEA Rattus norvegicus A0A0G2K162 R-RNO-6797553 https://reactome.org/PathwayBrowser/#/R-RNO-6797553 Protein 4.1 binds CASK IEA Rattus norvegicus A0A0G2K162 R-RNO-6797568 https://reactome.org/PathwayBrowser/#/R-RNO-6797568 NRXNs bind CASK:Protein 4.1 IEA Rattus norvegicus A0A0G2K171 R-RNO-199626 https://reactome.org/PathwayBrowser/#/R-RNO-199626 SLC19A2/3 transport extracellular THMN to cytosol IEA Rattus norvegicus A0A0G2K180 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus A0A0G2K180 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus A0A0G2K180 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus A0A0G2K180 R-RNO-173626 https://reactome.org/PathwayBrowser/#/R-RNO-173626 Activation of C1r IEA Rattus norvegicus A0A0G2K180 R-RNO-173631 https://reactome.org/PathwayBrowser/#/R-RNO-173631 Activation of C1s IEA Rattus norvegicus A0A0G2K180 R-RNO-1861621 https://reactome.org/PathwayBrowser/#/R-RNO-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K180 R-RNO-199161 https://reactome.org/PathwayBrowser/#/R-RNO-199161 Fc gamma receptors interact with antigen-bound IgG IEA Rattus norvegicus A0A0G2K180 R-RNO-2029268 https://reactome.org/PathwayBrowser/#/R-RNO-2029268 Phosphorylation and activation of PLCG IEA Rattus norvegicus A0A0G2K180 R-RNO-2029270 https://reactome.org/PathwayBrowser/#/R-RNO-2029270 Recruitment of PLCgamma to membrane IEA Rattus norvegicus A0A0G2K180 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K180 R-RNO-2029272 https://reactome.org/PathwayBrowser/#/R-RNO-2029272 Release of PLCG from FCGR IEA Rattus norvegicus A0A0G2K180 R-RNO-2029273 https://reactome.org/PathwayBrowser/#/R-RNO-2029273 PI3K binds to p-6Y-SYK IEA Rattus norvegicus A0A0G2K180 R-RNO-2029451 https://reactome.org/PathwayBrowser/#/R-RNO-2029451 Activation of RAC1 by VAV IEA Rattus norvegicus A0A0G2K180 R-RNO-2029452 https://reactome.org/PathwayBrowser/#/R-RNO-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Rattus norvegicus A0A0G2K180 R-RNO-2029453 https://reactome.org/PathwayBrowser/#/R-RNO-2029453 Phosphorylation of VAV IEA Rattus norvegicus A0A0G2K180 R-RNO-2029455 https://reactome.org/PathwayBrowser/#/R-RNO-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K180 R-RNO-2029457 https://reactome.org/PathwayBrowser/#/R-RNO-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K180 R-RNO-2029458 https://reactome.org/PathwayBrowser/#/R-RNO-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Rattus norvegicus A0A0G2K180 R-RNO-2029459 https://reactome.org/PathwayBrowser/#/R-RNO-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Rattus norvegicus A0A0G2K180 R-RNO-2029467 https://reactome.org/PathwayBrowser/#/R-RNO-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Rattus norvegicus A0A0G2K180 R-RNO-2029476 https://reactome.org/PathwayBrowser/#/R-RNO-2029476 Role of myosins in phagosome formation IEA Rattus norvegicus A0A0G2K180 R-RNO-2203516 https://reactome.org/PathwayBrowser/#/R-RNO-2203516 Alpha-1-Microglobulin is cleaved IEA Rattus norvegicus A0A0G2K180 R-RNO-2454192 https://reactome.org/PathwayBrowser/#/R-RNO-2454192 Allergen dependent IgE bound FCERI aggregation IEA Rattus norvegicus A0A0G2K180 R-RNO-2454208 https://reactome.org/PathwayBrowser/#/R-RNO-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Rattus norvegicus A0A0G2K180 R-RNO-2454240 https://reactome.org/PathwayBrowser/#/R-RNO-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Rattus norvegicus A0A0G2K180 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus A0A0G2K180 R-RNO-2730843 https://reactome.org/PathwayBrowser/#/R-RNO-2730843 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus A0A0G2K180 R-RNO-2730851 https://reactome.org/PathwayBrowser/#/R-RNO-2730851 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus A0A0G2K180 R-RNO-2730882 https://reactome.org/PathwayBrowser/#/R-RNO-2730882 Phosphorylation of PKC-theta IEA Rattus norvegicus A0A0G2K180 R-RNO-2730884 https://reactome.org/PathwayBrowser/#/R-RNO-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Rattus norvegicus A0A0G2K180 R-RNO-2730886 https://reactome.org/PathwayBrowser/#/R-RNO-2730886 Phosphorylation of SHC by SYK kinase IEA Rattus norvegicus A0A0G2K180 R-RNO-5690701 https://reactome.org/PathwayBrowser/#/R-RNO-5690701 SHP1 binds p-CD22 IEA Rattus norvegicus A0A0G2K180 R-RNO-5690702 https://reactome.org/PathwayBrowser/#/R-RNO-5690702 LYN phosphorylates CD22 IEA Rattus norvegicus A0A0G2K180 R-RNO-5690740 https://reactome.org/PathwayBrowser/#/R-RNO-5690740 CD22 binds B-cell receptor IEA Rattus norvegicus A0A0G2K180 R-RNO-8852266 https://reactome.org/PathwayBrowser/#/R-RNO-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Rattus norvegicus A0A0G2K180 R-RNO-8852481 https://reactome.org/PathwayBrowser/#/R-RNO-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Rattus norvegicus A0A0G2K180 R-RNO-8858428 https://reactome.org/PathwayBrowser/#/R-RNO-8858428 FCAMR binds IgA IEA Rattus norvegicus A0A0G2K180 R-RNO-8858498 https://reactome.org/PathwayBrowser/#/R-RNO-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Rattus norvegicus A0A0G2K180 R-RNO-9021306 https://reactome.org/PathwayBrowser/#/R-RNO-9021306 C1-Inh binds and inactivates C1r, C1s IEA Rattus norvegicus A0A0G2K180 R-RNO-9606151 https://reactome.org/PathwayBrowser/#/R-RNO-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Rattus norvegicus A0A0G2K180 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus A0A0G2K180 R-RNO-9724685 https://reactome.org/PathwayBrowser/#/R-RNO-9724685 IgE binds omalizumab IEA Rattus norvegicus A0A0G2K180 R-RNO-9725206 https://reactome.org/PathwayBrowser/#/R-RNO-9725206 IgE binds FCERI IEA Rattus norvegicus A0A0G2K180 R-RNO-983696 https://reactome.org/PathwayBrowser/#/R-RNO-983696 The Immunoglobulin of the BCR binds antigen IEA Rattus norvegicus A0A0G2K180 R-RNO-983700 https://reactome.org/PathwayBrowser/#/R-RNO-983700 SYK binds the activated BCR IEA Rattus norvegicus A0A0G2K180 R-RNO-983703 https://reactome.org/PathwayBrowser/#/R-RNO-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Rattus norvegicus A0A0G2K180 R-RNO-983707 https://reactome.org/PathwayBrowser/#/R-RNO-983707 SYK autophosphorylates at the activated BCR IEA Rattus norvegicus A0A0G2K1A1 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2K1A2 R-RNO-6789031 https://reactome.org/PathwayBrowser/#/R-RNO-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus A0A0G2K1A2 R-RNO-6789126 https://reactome.org/PathwayBrowser/#/R-RNO-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus A0A0G2K1A2 R-RNO-6789136 https://reactome.org/PathwayBrowser/#/R-RNO-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Rattus norvegicus A0A0G2K1A2 R-RNO-6798751 https://reactome.org/PathwayBrowser/#/R-RNO-6798751 Exocytosis of azurophil granule lumen proteins IEA Rattus norvegicus A0A0G2K1A2 R-RNO-8933635 https://reactome.org/PathwayBrowser/#/R-RNO-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Rattus norvegicus A0A0G2K1A8 R-RNO-8870332 https://reactome.org/PathwayBrowser/#/R-RNO-8870332 PTPN13:PLEKHA1,2 bind PI(3,4)P2 IEA Rattus norvegicus A0A0G2K1A9 R-RNO-6791221 https://reactome.org/PathwayBrowser/#/R-RNO-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA IEA Rattus norvegicus A0A0G2K1A9 R-RNO-6791222 https://reactome.org/PathwayBrowser/#/R-RNO-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Rattus norvegicus A0A0G2K1A9 R-RNO-6791227 https://reactome.org/PathwayBrowser/#/R-RNO-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Rattus norvegicus A0A0G2K1C4 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2K1C7 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2K1E1 R-RNO-1236943 https://reactome.org/PathwayBrowser/#/R-RNO-1236943 Loading of antigen peptide onto MHC class I molecule IEA Rattus norvegicus A0A0G2K1E1 R-RNO-1236954 https://reactome.org/PathwayBrowser/#/R-RNO-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Rattus norvegicus A0A0G2K1E1 R-RNO-1236964 https://reactome.org/PathwayBrowser/#/R-RNO-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Rattus norvegicus A0A0G2K1E1 R-RNO-1236965 https://reactome.org/PathwayBrowser/#/R-RNO-1236965 Export of peptide loaded MHC class I complex to PM IEA Rattus norvegicus A0A0G2K1E1 R-RNO-198955 https://reactome.org/PathwayBrowser/#/R-RNO-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Rattus norvegicus A0A0G2K1E1 R-RNO-198958 https://reactome.org/PathwayBrowser/#/R-RNO-198958 KIR2DL2/3 interacting with HLA-C group 1 (Cw4) IEA Rattus norvegicus A0A0G2K1E1 R-RNO-199169 https://reactome.org/PathwayBrowser/#/R-RNO-199169 MHC Class I interacts with CD160 IEA Rattus norvegicus A0A0G2K1E1 R-RNO-199558 https://reactome.org/PathwayBrowser/#/R-RNO-199558 KIR2DL1 interacting with HLA-C group 2 (Cw3) IEA Rattus norvegicus A0A0G2K1E1 R-RNO-199566 https://reactome.org/PathwayBrowser/#/R-RNO-199566 KIR3DL1 interacting with HLA Bw4 IEA Rattus norvegicus A0A0G2K1E1 R-RNO-199583 https://reactome.org/PathwayBrowser/#/R-RNO-199583 KIR2DS2 interacting with HLA-C group 1 (Cw3) IEA Rattus norvegicus A0A0G2K1E1 R-RNO-199587 https://reactome.org/PathwayBrowser/#/R-RNO-199587 KIR2DS1 interacting with HLA-C group 2 (Cw4) IEA Rattus norvegicus A0A0G2K1E1 R-RNO-210298 https://reactome.org/PathwayBrowser/#/R-RNO-210298 Interaction of DAP12 and KIR3DS1 IEA Rattus norvegicus A0A0G2K1E1 R-RNO-210309 https://reactome.org/PathwayBrowser/#/R-RNO-210309 Interaction of DAP12 and KIR2DS2 IEA Rattus norvegicus A0A0G2K1E1 R-RNO-2272753 https://reactome.org/PathwayBrowser/#/R-RNO-2272753 Interaction of DAP12 and KIR2DS4 IEA Rattus norvegicus A0A0G2K1E1 R-RNO-2272795 https://reactome.org/PathwayBrowser/#/R-RNO-2272795 Interaction of DAP12 and KIR2DS1 IEA Rattus norvegicus A0A0G2K1E1 R-RNO-6798739 https://reactome.org/PathwayBrowser/#/R-RNO-6798739 Exocytosis of azurophil granule membrane proteins IEA Rattus norvegicus A0A0G2K1E1 R-RNO-6798743 https://reactome.org/PathwayBrowser/#/R-RNO-6798743 Exocytosis of secretory granule membrane proteins IEA Rattus norvegicus A0A0G2K1E1 R-RNO-8863973 https://reactome.org/PathwayBrowser/#/R-RNO-8863973 Fusion of ERC and phagosome IEA Rattus norvegicus A0A0G2K1E1 R-RNO-8951499 https://reactome.org/PathwayBrowser/#/R-RNO-8951499 Loading of antigenic peptides on to class I MHC IEA Rattus norvegicus A0A0G2K1E1 R-RNO-983138 https://reactome.org/PathwayBrowser/#/R-RNO-983138 Transport of MHC heterotrimer to ER exit site IEA Rattus norvegicus A0A0G2K1E1 R-RNO-983142 https://reactome.org/PathwayBrowser/#/R-RNO-983142 Formation of peptide loading complex (PLC) IEA Rattus norvegicus A0A0G2K1E1 R-RNO-983145 https://reactome.org/PathwayBrowser/#/R-RNO-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Rattus norvegicus A0A0G2K1E1 R-RNO-983146 https://reactome.org/PathwayBrowser/#/R-RNO-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Rattus norvegicus A0A0G2K1E1 R-RNO-983161 https://reactome.org/PathwayBrowser/#/R-RNO-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex IEA Rattus norvegicus A0A0G2K1E1 R-RNO-983421 https://reactome.org/PathwayBrowser/#/R-RNO-983421 Journey of cargo through Golgi complex IEA Rattus norvegicus A0A0G2K1E1 R-RNO-983422 https://reactome.org/PathwayBrowser/#/R-RNO-983422 Disassembly of COPII coated vesicle IEA Rattus norvegicus A0A0G2K1E1 R-RNO-983424 https://reactome.org/PathwayBrowser/#/R-RNO-983424 Budding of COPII coated vesicle IEA Rattus norvegicus A0A0G2K1E1 R-RNO-983425 https://reactome.org/PathwayBrowser/#/R-RNO-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Rattus norvegicus A0A0G2K1E1 R-RNO-983427 https://reactome.org/PathwayBrowser/#/R-RNO-983427 Expression of peptide bound class I MHC on cell surface IEA Rattus norvegicus A0A0G2K1E2 R-RNO-202723 https://reactome.org/PathwayBrowser/#/R-RNO-202723 Integrin alpha5beta1 binds FN1 dimer IEA Rattus norvegicus A0A0G2K1E2 R-RNO-2327746 https://reactome.org/PathwayBrowser/#/R-RNO-2327746 FN1 aggregation IEA Rattus norvegicus A0A0G2K1E2 R-RNO-2328037 https://reactome.org/PathwayBrowser/#/R-RNO-2328037 Fibrillin-1 binds integrins IEA Rattus norvegicus A0A0G2K1E2 R-RNO-2426259 https://reactome.org/PathwayBrowser/#/R-RNO-2426259 COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 IEA Rattus norvegicus A0A0G2K1E2 R-RNO-265424 https://reactome.org/PathwayBrowser/#/R-RNO-265424 SPP1 (osteopontin) binds integrin alpha5beta1, alpha9beta1 IEA Rattus norvegicus A0A0G2K1E2 R-RNO-374686 https://reactome.org/PathwayBrowser/#/R-RNO-374686 L1 interaction with Integrins IEA Rattus norvegicus A0A0G2K1E2 R-RNO-4088264 https://reactome.org/PathwayBrowser/#/R-RNO-4088264 Endostatin binds integrin alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 IEA Rattus norvegicus A0A0G2K1E2 R-RNO-9624017 https://reactome.org/PathwayBrowser/#/R-RNO-9624017 p-SHC1 binds integrin alpha5beta1:fibronectin IEA Rattus norvegicus A0A0G2K1E2 R-RNO-9861484 https://reactome.org/PathwayBrowser/#/R-RNO-9861484 Phosphorylation of PTK2 (FAK) on tyrosine-397 in response to turbulent blood flow IEA Rattus norvegicus A0A0G2K1E2 R-RNO-9865184 https://reactome.org/PathwayBrowser/#/R-RNO-9865184 Phosphorylation of ABL1 on tyrosine-393 in response to oscillatory shear stress IEA Rattus norvegicus A0A0G2K1E2 R-RNO-9865215 https://reactome.org/PathwayBrowser/#/R-RNO-9865215 p-S26-ANXA2 binds integrin alpha5:beta1 at the plasma membrane IEA Rattus norvegicus A0A0G2K1E2 R-RNO-9865226 https://reactome.org/PathwayBrowser/#/R-RNO-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Rattus norvegicus A0A0G2K1E3 R-RNO-5159245 https://reactome.org/PathwayBrowser/#/R-RNO-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Rattus norvegicus A0A0G2K1E3 R-RNO-5244692 https://reactome.org/PathwayBrowser/#/R-RNO-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Rattus norvegicus A0A0G2K1E3 R-RNO-5637686 https://reactome.org/PathwayBrowser/#/R-RNO-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Rattus norvegicus A0A0G2K1E3 R-RNO-8936481 https://reactome.org/PathwayBrowser/#/R-RNO-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Rattus norvegicus A0A0G2K1E3 R-RNO-8936621 https://reactome.org/PathwayBrowser/#/R-RNO-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Rattus norvegicus A0A0G2K1E3 R-RNO-8937016 https://reactome.org/PathwayBrowser/#/R-RNO-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Rattus norvegicus A0A0G2K1E3 R-RNO-8937050 https://reactome.org/PathwayBrowser/#/R-RNO-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Rattus norvegicus A0A0G2K1E3 R-RNO-9676255 https://reactome.org/PathwayBrowser/#/R-RNO-9676255 Formation of the MLL2 complex IEA Rattus norvegicus A0A0G2K1E3 R-RNO-9818682 https://reactome.org/PathwayBrowser/#/R-RNO-9818682 MEN1 binds MLL2 complex IEA Rattus norvegicus A0A0G2K1E3 R-RNO-9821366 https://reactome.org/PathwayBrowser/#/R-RNO-9821366 AKAP8L binds MLL2 complex IEA Rattus norvegicus A0A0G2K1E3 R-RNO-9821902 https://reactome.org/PathwayBrowser/#/R-RNO-9821902 PSIP1 binds MEN1 associated with MLL2 complex IEA Rattus norvegicus A0A0G2K1E5 R-RNO-72180 https://reactome.org/PathwayBrowser/#/R-RNO-72180 Cleavage of mRNA at the 3'-end IEA Rattus norvegicus A0A0G2K1E5 R-RNO-72185 https://reactome.org/PathwayBrowser/#/R-RNO-72185 mRNA polyadenylation IEA Rattus norvegicus A0A0G2K1E5 R-RNO-72231 https://reactome.org/PathwayBrowser/#/R-RNO-72231 Formation of the Cleavage and Polyadenylation Complex IEA Rattus norvegicus A0A0G2K1E5 R-RNO-77589 https://reactome.org/PathwayBrowser/#/R-RNO-77589 Recognition of AAUAAA sequence by CPSF IEA Rattus norvegicus A0A0G2K1E5 R-RNO-77590 https://reactome.org/PathwayBrowser/#/R-RNO-77590 Recruitment of CstF to the CPSF Bound Pre-mRNA IEA Rattus norvegicus A0A0G2K1E5 R-RNO-77591 https://reactome.org/PathwayBrowser/#/R-RNO-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Rattus norvegicus A0A0G2K1E5 R-RNO-77592 https://reactome.org/PathwayBrowser/#/R-RNO-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Rattus norvegicus A0A0G2K1E5 R-RNO-77593 https://reactome.org/PathwayBrowser/#/R-RNO-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Rattus norvegicus A0A0G2K1E5 R-RNO-77594 https://reactome.org/PathwayBrowser/#/R-RNO-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Rattus norvegicus A0A0G2K1F2 R-RNO-200423 https://reactome.org/PathwayBrowser/#/R-RNO-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Rattus norvegicus A0A0G2K1F2 R-RNO-4167511 https://reactome.org/PathwayBrowser/#/R-RNO-4167511 HLCS biotinylates ACACB IEA Rattus norvegicus A0A0G2K1F2 R-RNO-8876889 https://reactome.org/PathwayBrowser/#/R-RNO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus A0A0G2K1H0 R-RNO-4754181 https://reactome.org/PathwayBrowser/#/R-RNO-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Rattus norvegicus A0A0G2K1H0 R-RNO-5661116 https://reactome.org/PathwayBrowser/#/R-RNO-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Rattus norvegicus A0A0G2K1H6 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2K1J1 R-RNO-9913330 https://reactome.org/PathwayBrowser/#/R-RNO-9913330 SGCG,SGCZ and SGCA, SGCE bind SGCB:SGCD IEA Rattus norvegicus A0A0G2K1J1 R-RNO-9913332 https://reactome.org/PathwayBrowser/#/R-RNO-9913332 DAG1(30-653), DAG1(654-895) and SSPN bind SGC IEA Rattus norvegicus A0A0G2K1J1 R-RNO-9913333 https://reactome.org/PathwayBrowser/#/R-RNO-9913333 DGC complex binds laminins IEA Rattus norvegicus A0A0G2K1J1 R-RNO-9913336 https://reactome.org/PathwayBrowser/#/R-RNO-9913336 SGC:DAG1:SSPN complex translocates to plasma membrane IEA Rattus norvegicus A0A0G2K1J1 R-RNO-9913338 https://reactome.org/PathwayBrowser/#/R-RNO-9913338 Sarcoglycan complex (SGC) translocates to the Golgi membrane IEA Rattus norvegicus A0A0G2K1J1 R-RNO-9913339 https://reactome.org/PathwayBrowser/#/R-RNO-9913339 Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC IEA Rattus norvegicus A0A0G2K1J1 R-RNO-9914537 https://reactome.org/PathwayBrowser/#/R-RNO-9914537 DGC complex binds AGRN and HSPG2 IEA Rattus norvegicus A0A0G2K1K5 R-RNO-8877475 https://reactome.org/PathwayBrowser/#/R-RNO-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Rattus norvegicus A0A0G2K1M1 R-RNO-8956568 https://reactome.org/PathwayBrowser/#/R-RNO-8956568 RUNX1 binds the core TAL1 complex IEA Rattus norvegicus A0A0G2K1P1 R-RNO-1675795 https://reactome.org/PathwayBrowser/#/R-RNO-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Rattus norvegicus A0A0G2K1P1 R-RNO-1676065 https://reactome.org/PathwayBrowser/#/R-RNO-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Rattus norvegicus A0A0G2K1P3 R-RNO-448958 https://reactome.org/PathwayBrowser/#/R-RNO-448958 Nuclear translocation of p38 MAPK IEA Rattus norvegicus A0A0G2K1Q0 R-RNO-1676109 https://reactome.org/PathwayBrowser/#/R-RNO-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Rattus norvegicus A0A0G2K1Q3 R-RNO-914010 https://reactome.org/PathwayBrowser/#/R-RNO-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Rattus norvegicus A0A0G2K1Q8 R-RNO-5683714 https://reactome.org/PathwayBrowser/#/R-RNO-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Rattus norvegicus A0A0G2K1R2 R-RNO-9933236 https://reactome.org/PathwayBrowser/#/R-RNO-9933236 SS18-containing ATPase complex binds SMARCC dimer:SMARCDs:BICRAs:BRD9 IEA Rattus norvegicus A0A0G2K1R2 R-RNO-9933237 https://reactome.org/PathwayBrowser/#/R-RNO-9933237 PBRM1-containing ATPase complex binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD&:PHF10 IEA Rattus norvegicus A0A0G2K1R2 R-RNO-9933238 https://reactome.org/PathwayBrowser/#/R-RNO-9933238 SS18-containing ATPase complex binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1:DPF1,2,3 IEA Rattus norvegicus A0A0G2K1R2 R-RNO-9934021 https://reactome.org/PathwayBrowser/#/R-RNO-9934021 Formation of neuronal progenitor BAF (npBAF) IEA Rattus norvegicus A0A0G2K1R2 R-RNO-9934024 https://reactome.org/PathwayBrowser/#/R-RNO-9934024 SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10 IEA Rattus norvegicus A0A0G2K1R8 R-RNO-2990840 https://reactome.org/PathwayBrowser/#/R-RNO-2990840 SENP1,2,5 proteolytically process SUMO1 IEA Rattus norvegicus A0A0G2K1R8 R-RNO-2990842 https://reactome.org/PathwayBrowser/#/R-RNO-2990842 SENP1,2,5 proteolytically process SUMO2 IEA Rattus norvegicus A0A0G2K1R8 R-RNO-2993763 https://reactome.org/PathwayBrowser/#/R-RNO-2993763 SENP1,2,5 proteolytically process SUMO3 IEA Rattus norvegicus A0A0G2K1R8 R-RNO-9693125 https://reactome.org/PathwayBrowser/#/R-RNO-9693125 RHOF binds effectors at the plasma membrane IEA Rattus norvegicus A0A0G2K1X3 R-RNO-5624949 https://reactome.org/PathwayBrowser/#/R-RNO-5624949 Assembly of the anterograde IFT train IEA Rattus norvegicus A0A0G2K1X3 R-RNO-5624952 https://reactome.org/PathwayBrowser/#/R-RNO-5624952 Assembly of the retrograde IFT train IEA Rattus norvegicus A0A0G2K1X3 R-RNO-5625416 https://reactome.org/PathwayBrowser/#/R-RNO-5625416 Anterograde IFT IEA Rattus norvegicus A0A0G2K1X3 R-RNO-5625421 https://reactome.org/PathwayBrowser/#/R-RNO-5625421 The anterograde IFT train dissociates IEA Rattus norvegicus A0A0G2K1X3 R-RNO-5625424 https://reactome.org/PathwayBrowser/#/R-RNO-5625424 The retrograde IFT train dissociates IEA Rattus norvegicus A0A0G2K1X3 R-RNO-5625426 https://reactome.org/PathwayBrowser/#/R-RNO-5625426 Retrograde IFT IEA Rattus norvegicus A0A0G2K1Z1 R-RNO-4724284 https://reactome.org/PathwayBrowser/#/R-RNO-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Rattus norvegicus A0A0G2K1Z1 R-RNO-4754187 https://reactome.org/PathwayBrowser/#/R-RNO-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Rattus norvegicus A0A0G2K1Z1 R-RNO-5661115 https://reactome.org/PathwayBrowser/#/R-RNO-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Rattus norvegicus A0A0G2K1Z1 R-RNO-5661121 https://reactome.org/PathwayBrowser/#/R-RNO-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Rattus norvegicus A0A0G2K210 R-RNO-109699 https://reactome.org/PathwayBrowser/#/R-RNO-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K210 R-RNO-190261 https://reactome.org/PathwayBrowser/#/R-RNO-190261 FGFR3c binds to FGF IEA Rattus norvegicus A0A0G2K210 R-RNO-190263 https://reactome.org/PathwayBrowser/#/R-RNO-190263 FGFR3b binds to FGF IEA Rattus norvegicus A0A0G2K210 R-RNO-190385 https://reactome.org/PathwayBrowser/#/R-RNO-190385 Autocatalytic phosphorylation of FGFR3b IEA Rattus norvegicus A0A0G2K210 R-RNO-190388 https://reactome.org/PathwayBrowser/#/R-RNO-190388 Autocatalytic phosphorylation of FGFR3c IEA Rattus norvegicus A0A0G2K210 R-RNO-2316434 https://reactome.org/PathwayBrowser/#/R-RNO-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654148 https://reactome.org/PathwayBrowser/#/R-RNO-5654148 p-4Y-PLCG1 dissociates from activated FGFR3 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654222 https://reactome.org/PathwayBrowser/#/R-RNO-5654222 Activated FGFR3 phosphorylates PLCG1 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654224 https://reactome.org/PathwayBrowser/#/R-RNO-5654224 Activated FGFR3 binds PLCG1 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654408 https://reactome.org/PathwayBrowser/#/R-RNO-5654408 Activated FGFR3 phosphorylates FRS2 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654409 https://reactome.org/PathwayBrowser/#/R-RNO-5654409 Activated FGFR3 binds FRS2 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654413 https://reactome.org/PathwayBrowser/#/R-RNO-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus A0A0G2K210 R-RNO-5654416 https://reactome.org/PathwayBrowser/#/R-RNO-5654416 Activated FGFR3:pFRS binds GRB2:SOS1 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654565 https://reactome.org/PathwayBrowser/#/R-RNO-5654565 Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654623 https://reactome.org/PathwayBrowser/#/R-RNO-5654623 Activated FGFR3 binds FRS3 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654625 https://reactome.org/PathwayBrowser/#/R-RNO-5654625 Activated FGFR3 binds SHC1 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654628 https://reactome.org/PathwayBrowser/#/R-RNO-5654628 Activated FGFR3 phosphorylates FRS3 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654631 https://reactome.org/PathwayBrowser/#/R-RNO-5654631 Activated FGFR3 phosphorylates PPTN11 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654633 https://reactome.org/PathwayBrowser/#/R-RNO-5654633 Activated FGFR3:p-FRS bind to PPTN11 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654634 https://reactome.org/PathwayBrowser/#/R-RNO-5654634 Activated FGFR3 phosphorylates SHC1 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654637 https://reactome.org/PathwayBrowser/#/R-RNO-5654637 Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654640 https://reactome.org/PathwayBrowser/#/R-RNO-5654640 Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Rattus norvegicus A0A0G2K210 R-RNO-5654641 https://reactome.org/PathwayBrowser/#/R-RNO-5654641 Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654643 https://reactome.org/PathwayBrowser/#/R-RNO-5654643 Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Rattus norvegicus A0A0G2K210 R-RNO-5654646 https://reactome.org/PathwayBrowser/#/R-RNO-5654646 Activated FGFR3:p-SHC1 binds GRB2:SOS1 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654647 https://reactome.org/PathwayBrowser/#/R-RNO-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Rattus norvegicus A0A0G2K210 R-RNO-5654679 https://reactome.org/PathwayBrowser/#/R-RNO-5654679 CBL ubiquitinates FRS2 and FGFR3 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654705 https://reactome.org/PathwayBrowser/#/R-RNO-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654709 https://reactome.org/PathwayBrowser/#/R-RNO-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K210 R-RNO-5654730 https://reactome.org/PathwayBrowser/#/R-RNO-5654730 p-CBL:GRB2 binds p-FRS2:activated FGFR3 IEA Rattus norvegicus A0A0G2K210 R-RNO-5672965 https://reactome.org/PathwayBrowser/#/R-RNO-5672965 RAS GEFs promote RAS nucleotide exchange IEA Rattus norvegicus A0A0G2K210 R-RNO-8941628 https://reactome.org/PathwayBrowser/#/R-RNO-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Rattus norvegicus A0A0G2K213 R-RNO-174425 https://reactome.org/PathwayBrowser/#/R-RNO-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Rattus norvegicus A0A0G2K213 R-RNO-174427 https://reactome.org/PathwayBrowser/#/R-RNO-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Rattus norvegicus A0A0G2K213 R-RNO-174452 https://reactome.org/PathwayBrowser/#/R-RNO-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Rattus norvegicus A0A0G2K213 R-RNO-9668597 https://reactome.org/PathwayBrowser/#/R-RNO-9668597 DNA polymerase:primase binds G-strand of the telomere IEA Rattus norvegicus A0A0G2K213 R-RNO-9668831 https://reactome.org/PathwayBrowser/#/R-RNO-9668831 CST complex formation IEA Rattus norvegicus A0A0G2K229 R-RNO-5173005 https://reactome.org/PathwayBrowser/#/R-RNO-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Rattus norvegicus A0A0G2K229 R-RNO-5173192 https://reactome.org/PathwayBrowser/#/R-RNO-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Rattus norvegicus A0A0G2K230 R-RNO-6809393 https://reactome.org/PathwayBrowser/#/R-RNO-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Rattus norvegicus A0A0G2K230 R-RNO-6810357 https://reactome.org/PathwayBrowser/#/R-RNO-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Rattus norvegicus A0A0G2K230 R-RNO-6810937 https://reactome.org/PathwayBrowser/#/R-RNO-6810937 Lamellar bodies bind the early cornified envelope IEA Rattus norvegicus A0A0G2K230 R-RNO-6814387 https://reactome.org/PathwayBrowser/#/R-RNO-6814387 CASP14 cleaves filaggrin IEA Rattus norvegicus A0A0G2K230 R-RNO-6814695 https://reactome.org/PathwayBrowser/#/R-RNO-6814695 PERP binds desmosomes IEA Rattus norvegicus A0A0G2K230 R-RNO-6814734 https://reactome.org/PathwayBrowser/#/R-RNO-6814734 CDSN binds the cornified envelope IEA Rattus norvegicus A0A0G2K230 R-RNO-6814764 https://reactome.org/PathwayBrowser/#/R-RNO-6814764 Plasma membrane resorption IEA Rattus norvegicus A0A0G2K254 R-RNO-141409 https://reactome.org/PathwayBrowser/#/R-RNO-141409 Mad1 binds kinetochore IEA Rattus norvegicus A0A0G2K254 R-RNO-141422 https://reactome.org/PathwayBrowser/#/R-RNO-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Rattus norvegicus A0A0G2K254 R-RNO-141431 https://reactome.org/PathwayBrowser/#/R-RNO-141431 MAD2 associates with the Mad1 kinetochore complex IEA Rattus norvegicus A0A0G2K254 R-RNO-141439 https://reactome.org/PathwayBrowser/#/R-RNO-141439 Release of activated MAD2 from kinetochores IEA Rattus norvegicus A0A0G2K254 R-RNO-1638803 https://reactome.org/PathwayBrowser/#/R-RNO-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Rattus norvegicus A0A0G2K254 R-RNO-1638821 https://reactome.org/PathwayBrowser/#/R-RNO-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Rattus norvegicus A0A0G2K254 R-RNO-2467809 https://reactome.org/PathwayBrowser/#/R-RNO-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Rattus norvegicus A0A0G2K254 R-RNO-2467811 https://reactome.org/PathwayBrowser/#/R-RNO-2467811 Separation of sister chromatids IEA Rattus norvegicus A0A0G2K254 R-RNO-2468287 https://reactome.org/PathwayBrowser/#/R-RNO-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Rattus norvegicus A0A0G2K254 R-RNO-2484822 https://reactome.org/PathwayBrowser/#/R-RNO-2484822 Kinetochore assembly IEA Rattus norvegicus A0A0G2K254 R-RNO-375302 https://reactome.org/PathwayBrowser/#/R-RNO-375302 Kinetochore capture of astral microtubules IEA Rattus norvegicus A0A0G2K254 R-RNO-5666129 https://reactome.org/PathwayBrowser/#/R-RNO-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Rattus norvegicus A0A0G2K254 R-RNO-5666160 https://reactome.org/PathwayBrowser/#/R-RNO-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Rattus norvegicus A0A0G2K254 R-RNO-5666169 https://reactome.org/PathwayBrowser/#/R-RNO-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Rattus norvegicus A0A0G2K254 R-RNO-9648114 https://reactome.org/PathwayBrowser/#/R-RNO-9648114 EML4 recruits NUDC to mitotic spindle IEA Rattus norvegicus A0A0G2K261 R-RNO-9838081 https://reactome.org/PathwayBrowser/#/R-RNO-9838081 LONP1 degrades mitochondrial matrix proteins IEA Rattus norvegicus A0A0G2K261 R-RNO-9838093 https://reactome.org/PathwayBrowser/#/R-RNO-9838093 LONP1 binds mitochondrial matrix proteins IEA Rattus norvegicus A0A0G2K264 R-RNO-5419261 https://reactome.org/PathwayBrowser/#/R-RNO-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Rattus norvegicus A0A0G2K264 R-RNO-5419264 https://reactome.org/PathwayBrowser/#/R-RNO-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Rattus norvegicus A0A0G2K264 R-RNO-5419271 https://reactome.org/PathwayBrowser/#/R-RNO-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Rattus norvegicus A0A0G2K264 R-RNO-5419273 https://reactome.org/PathwayBrowser/#/R-RNO-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Rattus norvegicus A0A0G2K264 R-RNO-5419281 https://reactome.org/PathwayBrowser/#/R-RNO-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Rattus norvegicus A0A0G2K283 R-RNO-9770141 https://reactome.org/PathwayBrowser/#/R-RNO-9770141 Formation of the Spliceosomal C* complex IEA Rattus norvegicus A0A0G2K283 R-RNO-9770236 https://reactome.org/PathwayBrowser/#/R-RNO-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Rattus norvegicus A0A0G2K2A5 R-RNO-5665854 https://reactome.org/PathwayBrowser/#/R-RNO-5665854 ADRM1:26S proteaseome binds UCHL5 IEA Rattus norvegicus A0A0G2K2A5 R-RNO-5689544 https://reactome.org/PathwayBrowser/#/R-RNO-5689544 UCHL5 binds INO80 complex IEA Rattus norvegicus A0A0G2K2B0 R-RNO-3108203 https://reactome.org/PathwayBrowser/#/R-RNO-3108203 PRC1 SUMOylates CTBP1 with SUMO2,3 IEA Rattus norvegicus A0A0G2K2B0 R-RNO-3108209 https://reactome.org/PathwayBrowser/#/R-RNO-3108209 PRC1 SUMOylates CTBP1 with SUMO1 IEA Rattus norvegicus A0A0G2K2B0 R-RNO-3229089 https://reactome.org/PathwayBrowser/#/R-RNO-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Rattus norvegicus A0A0G2K2B0 R-RNO-3229102 https://reactome.org/PathwayBrowser/#/R-RNO-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Rattus norvegicus A0A0G2K2B0 R-RNO-3927824 https://reactome.org/PathwayBrowser/#/R-RNO-3927824 PRC1 SUMOylates CASP8AP2 with SUMO1 IEA Rattus norvegicus A0A0G2K2B0 R-RNO-4551655 https://reactome.org/PathwayBrowser/#/R-RNO-4551655 CBX4 SUMOylates BMI1 in PRC1 with SUMO1 IEA Rattus norvegicus A0A0G2K2B0 R-RNO-4551727 https://reactome.org/PathwayBrowser/#/R-RNO-4551727 CBX4 SUMOylates CBX4 in PRC1 with SUMO1 IEA Rattus norvegicus A0A0G2K2B0 R-RNO-4570463 https://reactome.org/PathwayBrowser/#/R-RNO-4570463 CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 IEA Rattus norvegicus A0A0G2K2B0 R-RNO-4570499 https://reactome.org/PathwayBrowser/#/R-RNO-4570499 CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 IEA Rattus norvegicus A0A0G2K2B0 R-RNO-8937989 https://reactome.org/PathwayBrowser/#/R-RNO-8937989 RUNX1 binds PRC1 complexes IEA Rattus norvegicus A0A0G2K2B0 R-RNO-8954082 https://reactome.org/PathwayBrowser/#/R-RNO-8954082 E2F6 binds the PRC1 complex IEA Rattus norvegicus A0A0G2K2F9 R-RNO-8867370 https://reactome.org/PathwayBrowser/#/R-RNO-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Rattus norvegicus A0A0G2K2H4 R-RNO-381091 https://reactome.org/PathwayBrowser/#/R-RNO-381091 IRE1 dimer autophosphorylates IEA Rattus norvegicus A0A0G2K2H4 R-RNO-381109 https://reactome.org/PathwayBrowser/#/R-RNO-381109 IRE1 binds IRE1 forming dimer IEA Rattus norvegicus A0A0G2K2I4 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2K2K7 R-RNO-8848395 https://reactome.org/PathwayBrowser/#/R-RNO-8848395 IL18:IL18R1 binds IL18RAP IEA Rattus norvegicus A0A0G2K2M3 R-RNO-3249370 https://reactome.org/PathwayBrowser/#/R-RNO-3249370 p-S407,Y641-STAT6 dimer migrates to the nucleus IEA Rattus norvegicus A0A0G2K2M3 R-RNO-3249371 https://reactome.org/PathwayBrowser/#/R-RNO-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Rattus norvegicus A0A0G2K2M3 R-RNO-3249372 https://reactome.org/PathwayBrowser/#/R-RNO-3249372 p-S407,Y641-STAT6 is dimerized IEA Rattus norvegicus A0A0G2K2M3 R-RNO-3249378 https://reactome.org/PathwayBrowser/#/R-RNO-3249378 STING recruits TBK1 and STAT6 IEA Rattus norvegicus A0A0G2K2M3 R-RNO-3249379 https://reactome.org/PathwayBrowser/#/R-RNO-3249379 p-S407-STAT6 is phosphorylated at Tyr641 IEA Rattus norvegicus A0A0G2K2M3 R-RNO-3249390 https://reactome.org/PathwayBrowser/#/R-RNO-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Rattus norvegicus A0A0G2K2M3 R-RNO-380782 https://reactome.org/PathwayBrowser/#/R-RNO-380782 STAT binds to the active receptor IEA Rattus norvegicus A0A0G2K2M3 R-RNO-6786072 https://reactome.org/PathwayBrowser/#/R-RNO-6786072 p-Y705-STAT3,p-Y641-STAT6 dissociate IEA Rattus norvegicus A0A0G2K2M3 R-RNO-6786095 https://reactome.org/PathwayBrowser/#/R-RNO-6786095 JAK1 phosphorylates STAT3,STAT6 IEA Rattus norvegicus A0A0G2K2M3 R-RNO-6786097 https://reactome.org/PathwayBrowser/#/R-RNO-6786097 p-Y705-STAT3, p-Y641-STAT6 dimerise IEA Rattus norvegicus A0A0G2K2M3 R-RNO-6786124 https://reactome.org/PathwayBrowser/#/R-RNO-6786124 STAT3,STAT6 bind p-Y-IL4R IEA Rattus norvegicus A0A0G2K2M3 R-RNO-6786293 https://reactome.org/PathwayBrowser/#/R-RNO-6786293 p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus IEA Rattus norvegicus A0A0G2K2M3 R-RNO-6788571 https://reactome.org/PathwayBrowser/#/R-RNO-6788571 STAT1,STAT3,STAT6 bind IL13:IL13R type II IEA Rattus norvegicus A0A0G2K2M3 R-RNO-6788582 https://reactome.org/PathwayBrowser/#/R-RNO-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Rattus norvegicus A0A0G2K2M3 R-RNO-6788622 https://reactome.org/PathwayBrowser/#/R-RNO-6788622 p-Y-STATs dimerize IEA Rattus norvegicus A0A0G2K2M3 R-RNO-6788623 https://reactome.org/PathwayBrowser/#/R-RNO-6788623 p-Y-STATs translocate to nucleus IEA Rattus norvegicus A0A0G2K2M3 R-RNO-6788628 https://reactome.org/PathwayBrowser/#/R-RNO-6788628 p-Y-STATs dissociate IEA Rattus norvegicus A0A0G2K2P5 R-RNO-191636 https://reactome.org/PathwayBrowser/#/R-RNO-191636 Phosphorylation of Cx43 by c-src IEA Rattus norvegicus A0A0G2K2P5 R-RNO-191654 https://reactome.org/PathwayBrowser/#/R-RNO-191654 c-src associates with Cx43 in gap junctions IEA Rattus norvegicus A0A0G2K2P5 R-RNO-2064417 https://reactome.org/PathwayBrowser/#/R-RNO-2064417 WWTR1 (TAZ) binds ZO-1 (TJP1) IEA Rattus norvegicus A0A0G2K2P5 R-RNO-351913 https://reactome.org/PathwayBrowser/#/R-RNO-351913 Caspase-mediated cleavage of TJP1 IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-1650808 https://reactome.org/PathwayBrowser/#/R-RNO-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-1980233 https://reactome.org/PathwayBrowser/#/R-RNO-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-1981104 https://reactome.org/PathwayBrowser/#/R-RNO-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-1981120 https://reactome.org/PathwayBrowser/#/R-RNO-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-1981128 https://reactome.org/PathwayBrowser/#/R-RNO-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-1981157 https://reactome.org/PathwayBrowser/#/R-RNO-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-2002460 https://reactome.org/PathwayBrowser/#/R-RNO-2002460 P4HB binds Collagen chains IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-2152276 https://reactome.org/PathwayBrowser/#/R-RNO-2152276 Secretion of transmembrane collagens IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-2167942 https://reactome.org/PathwayBrowser/#/R-RNO-2167942 Collagen type XIII ectodomain shedding IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-2484965 https://reactome.org/PathwayBrowser/#/R-RNO-2484965 Collagen type XIII binds Integrin alpha1beta1 IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-8944261 https://reactome.org/PathwayBrowser/#/R-RNO-8944261 Association of procollagen type XIII IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-8948219 https://reactome.org/PathwayBrowser/#/R-RNO-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-8948222 https://reactome.org/PathwayBrowser/#/R-RNO-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-8948224 https://reactome.org/PathwayBrowser/#/R-RNO-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-8948228 https://reactome.org/PathwayBrowser/#/R-RNO-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-8948231 https://reactome.org/PathwayBrowser/#/R-RNO-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-8948232 https://reactome.org/PathwayBrowser/#/R-RNO-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Rattus norvegicus A0A0G2K2Q8 R-RNO-8948234 https://reactome.org/PathwayBrowser/#/R-RNO-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K2R4 R-RNO-8854209 https://reactome.org/PathwayBrowser/#/R-RNO-8854209 TBC1D10A binds JFC1 IEA Rattus norvegicus A0A0G2K2S9 R-RNO-2032781 https://reactome.org/PathwayBrowser/#/R-RNO-2032781 WWTR1 (TAZ) binds TEAD IEA Rattus norvegicus A0A0G2K2S9 R-RNO-8871260 https://reactome.org/PathwayBrowser/#/R-RNO-8871260 YAP1 binds TEAD2 IEA Rattus norvegicus A0A0G2K2S9 R-RNO-8951676 https://reactome.org/PathwayBrowser/#/R-RNO-8951676 RUNX3 binds TEADs and YAP1 IEA Rattus norvegicus A0A0G2K2T2 R-RNO-8954398 https://reactome.org/PathwayBrowser/#/R-RNO-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Rattus norvegicus A0A0G2K2T5 R-RNO-199518 https://reactome.org/PathwayBrowser/#/R-RNO-199518 C3d-complexed antigen binds to complement receptor IEA Rattus norvegicus A0A0G2K2V5 R-RNO-265177 https://reactome.org/PathwayBrowser/#/R-RNO-265177 Exocyst complex formation IEA Rattus norvegicus A0A0G2K2V5 R-RNO-5623524 https://reactome.org/PathwayBrowser/#/R-RNO-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Rattus norvegicus A0A0G2K2V5 R-RNO-5623527 https://reactome.org/PathwayBrowser/#/R-RNO-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Rattus norvegicus A0A0G2K2W0 R-RNO-6798747 https://reactome.org/PathwayBrowser/#/R-RNO-6798747 Exocytosis of tertiary granule membrane proteins IEA Rattus norvegicus A0A0G2K2W0 R-RNO-6799350 https://reactome.org/PathwayBrowser/#/R-RNO-6799350 Exocytosis of specific granule membrane proteins IEA Rattus norvegicus A0A0G2K2Z0 R-RNO-9647746 https://reactome.org/PathwayBrowser/#/R-RNO-9647746 EML4 trimerizes IEA Rattus norvegicus A0A0G2K2Z0 R-RNO-9648017 https://reactome.org/PathwayBrowser/#/R-RNO-9648017 EML4 binds to microtubules IEA Rattus norvegicus A0A0G2K2Z0 R-RNO-9648114 https://reactome.org/PathwayBrowser/#/R-RNO-9648114 EML4 recruits NUDC to mitotic spindle IEA Rattus norvegicus A0A0G2K2Z2 R-RNO-1675949 https://reactome.org/PathwayBrowser/#/R-RNO-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Rattus norvegicus A0A0G2K2Z2 R-RNO-1676177 https://reactome.org/PathwayBrowser/#/R-RNO-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Rattus norvegicus A0A0G2K309 R-RNO-70634 https://reactome.org/PathwayBrowser/#/R-RNO-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) IEA Rattus norvegicus A0A0G2K313 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2K313 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus A0A0G2K313 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2K313 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2K320 R-RNO-5685607 https://reactome.org/PathwayBrowser/#/R-RNO-5685607 Sialic acid binds SIGLEC IEA Rattus norvegicus A0A0G2K331 R-RNO-8874204 https://reactome.org/PathwayBrowser/#/R-RNO-8874204 MBTPS1 (S1P) cleaves CREB3 IEA Rattus norvegicus A0A0G2K331 R-RNO-8874849 https://reactome.org/PathwayBrowser/#/R-RNO-8874849 CREBRF binds CREB3 IEA Rattus norvegicus A0A0G2K344 R-RNO-109699 https://reactome.org/PathwayBrowser/#/R-RNO-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-114542 https://reactome.org/PathwayBrowser/#/R-RNO-114542 RAC1,RAC2,RHOG activate PI3K IEA Rattus norvegicus A0A0G2K344 R-RNO-1250189 https://reactome.org/PathwayBrowser/#/R-RNO-1250189 Binding of PI3K to ERBB2:p-ERBB3 heterodimer IEA Rattus norvegicus A0A0G2K344 R-RNO-1250346 https://reactome.org/PathwayBrowser/#/R-RNO-1250346 Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers IEA Rattus norvegicus A0A0G2K344 R-RNO-1250353 https://reactome.org/PathwayBrowser/#/R-RNO-1250353 Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers IEA Rattus norvegicus A0A0G2K344 R-RNO-1250370 https://reactome.org/PathwayBrowser/#/R-RNO-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Rattus norvegicus A0A0G2K344 R-RNO-1250462 https://reactome.org/PathwayBrowser/#/R-RNO-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Rattus norvegicus A0A0G2K344 R-RNO-1306957 https://reactome.org/PathwayBrowser/#/R-RNO-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Rattus norvegicus A0A0G2K344 R-RNO-1306965 https://reactome.org/PathwayBrowser/#/R-RNO-1306965 Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Rattus norvegicus A0A0G2K344 R-RNO-1306979 https://reactome.org/PathwayBrowser/#/R-RNO-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Rattus norvegicus A0A0G2K344 R-RNO-1433514 https://reactome.org/PathwayBrowser/#/R-RNO-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Rattus norvegicus A0A0G2K344 R-RNO-1562641 https://reactome.org/PathwayBrowser/#/R-RNO-1562641 Indirect recruitment of PI3K to KIT via p(Y)-GAB2 IEA Rattus norvegicus A0A0G2K344 R-RNO-1676048 https://reactome.org/PathwayBrowser/#/R-RNO-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Rattus norvegicus A0A0G2K344 R-RNO-1676109 https://reactome.org/PathwayBrowser/#/R-RNO-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Rattus norvegicus A0A0G2K344 R-RNO-177927 https://reactome.org/PathwayBrowser/#/R-RNO-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 IEA Rattus norvegicus A0A0G2K344 R-RNO-177939 https://reactome.org/PathwayBrowser/#/R-RNO-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Rattus norvegicus A0A0G2K344 R-RNO-186780 https://reactome.org/PathwayBrowser/#/R-RNO-186780 PI3-kinase binds to the active receptor IEA Rattus norvegicus A0A0G2K344 R-RNO-186800 https://reactome.org/PathwayBrowser/#/R-RNO-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-198266 https://reactome.org/PathwayBrowser/#/R-RNO-198266 PI3K produces PIP3 and other phosphatidyl inositides IEA Rattus norvegicus A0A0G2K344 R-RNO-198315 https://reactome.org/PathwayBrowser/#/R-RNO-198315 Active IRS recruits PI3K to the plasma membrane and activates it IEA Rattus norvegicus A0A0G2K344 R-RNO-201510 https://reactome.org/PathwayBrowser/#/R-RNO-201510 PI3K synthesizes PIP3 downstream of ALK IEA Rattus norvegicus A0A0G2K344 R-RNO-201515 https://reactome.org/PathwayBrowser/#/R-RNO-201515 Active ALK recruits PI3K IEA Rattus norvegicus A0A0G2K344 R-RNO-202203 https://reactome.org/PathwayBrowser/#/R-RNO-202203 Recruitment of PI3K to plasma membrane IEA Rattus norvegicus A0A0G2K344 R-RNO-202365 https://reactome.org/PathwayBrowser/#/R-RNO-202365 PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-2029273 https://reactome.org/PathwayBrowser/#/R-RNO-2029273 PI3K binds to p-6Y-SYK IEA Rattus norvegicus A0A0G2K344 R-RNO-204798 https://reactome.org/PathwayBrowser/#/R-RNO-204798 Interaction of Tie2 and p85 of PI3K IEA Rattus norvegicus A0A0G2K344 R-RNO-205262 https://reactome.org/PathwayBrowser/#/R-RNO-205262 Direct recruitment of PI3K to p-KIT IEA Rattus norvegicus A0A0G2K344 R-RNO-2316434 https://reactome.org/PathwayBrowser/#/R-RNO-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-2424480 https://reactome.org/PathwayBrowser/#/R-RNO-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-2424482 https://reactome.org/PathwayBrowser/#/R-RNO-2424482 p85 regulatory unit of PI3K binds p-6Y-SYK IEA Rattus norvegicus A0A0G2K344 R-RNO-2730842 https://reactome.org/PathwayBrowser/#/R-RNO-2730842 PI3K associates with phosphorylated GAB2 IEA Rattus norvegicus A0A0G2K344 R-RNO-2730870 https://reactome.org/PathwayBrowser/#/R-RNO-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Rattus norvegicus A0A0G2K344 R-RNO-388830 https://reactome.org/PathwayBrowser/#/R-RNO-388830 PI3K binds ICOS IEA Rattus norvegicus A0A0G2K344 R-RNO-388832 https://reactome.org/PathwayBrowser/#/R-RNO-388832 PI3K binds CD28 IEA Rattus norvegicus A0A0G2K344 R-RNO-389158 https://reactome.org/PathwayBrowser/#/R-RNO-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-416358 https://reactome.org/PathwayBrowser/#/R-RNO-416358 G alpha (q) inhibits PI3K alpha IEA Rattus norvegicus A0A0G2K344 R-RNO-437162 https://reactome.org/PathwayBrowser/#/R-RNO-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-508247 https://reactome.org/PathwayBrowser/#/R-RNO-508247 Gab2 binds the p85 subunit of Class 1A PI3 kinases IEA Rattus norvegicus A0A0G2K344 R-RNO-5218819 https://reactome.org/PathwayBrowser/#/R-RNO-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-5357479 https://reactome.org/PathwayBrowser/#/R-RNO-5357479 p-AXL binds PI3K IEA Rattus norvegicus A0A0G2K344 R-RNO-5654591 https://reactome.org/PathwayBrowser/#/R-RNO-5654591 Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Rattus norvegicus A0A0G2K344 R-RNO-5654596 https://reactome.org/PathwayBrowser/#/R-RNO-5654596 Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Rattus norvegicus A0A0G2K344 R-RNO-5654614 https://reactome.org/PathwayBrowser/#/R-RNO-5654614 Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Rattus norvegicus A0A0G2K344 R-RNO-5654622 https://reactome.org/PathwayBrowser/#/R-RNO-5654622 Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Rattus norvegicus A0A0G2K344 R-RNO-5654640 https://reactome.org/PathwayBrowser/#/R-RNO-5654640 Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Rattus norvegicus A0A0G2K344 R-RNO-5654643 https://reactome.org/PathwayBrowser/#/R-RNO-5654643 Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Rattus norvegicus A0A0G2K344 R-RNO-5654662 https://reactome.org/PathwayBrowser/#/R-RNO-5654662 Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Rattus norvegicus A0A0G2K344 R-RNO-5654669 https://reactome.org/PathwayBrowser/#/R-RNO-5654669 Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA IEA Rattus norvegicus A0A0G2K344 R-RNO-5654690 https://reactome.org/PathwayBrowser/#/R-RNO-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-5654692 https://reactome.org/PathwayBrowser/#/R-RNO-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-5654697 https://reactome.org/PathwayBrowser/#/R-RNO-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-5654701 https://reactome.org/PathwayBrowser/#/R-RNO-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-5654705 https://reactome.org/PathwayBrowser/#/R-RNO-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-5654709 https://reactome.org/PathwayBrowser/#/R-RNO-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-5654714 https://reactome.org/PathwayBrowser/#/R-RNO-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-5654717 https://reactome.org/PathwayBrowser/#/R-RNO-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-74737 https://reactome.org/PathwayBrowser/#/R-RNO-74737 p-Y-IRS1,p-Y-IRS2 bind PI3K IEA Rattus norvegicus A0A0G2K344 R-RNO-879917 https://reactome.org/PathwayBrowser/#/R-RNO-879917 CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated IEA Rattus norvegicus A0A0G2K344 R-RNO-8851954 https://reactome.org/PathwayBrowser/#/R-RNO-8851954 Phosphorylated GAB1 recruits PI3K to MET IEA Rattus norvegicus A0A0G2K344 R-RNO-8852019 https://reactome.org/PathwayBrowser/#/R-RNO-8852019 MET bound PI3K generates PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-8854905 https://reactome.org/PathwayBrowser/#/R-RNO-8854905 p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K IEA Rattus norvegicus A0A0G2K344 R-RNO-9012657 https://reactome.org/PathwayBrowser/#/R-RNO-9012657 EPO:phospho-EPOR:phospho-JAK2:LYN:phospho-IRS2 binds PI3K IEA Rattus norvegicus A0A0G2K344 R-RNO-9013145 https://reactome.org/PathwayBrowser/#/R-RNO-9013145 RAC1 binds effectors at the plasma membrane IEA Rattus norvegicus A0A0G2K344 R-RNO-9014294 https://reactome.org/PathwayBrowser/#/R-RNO-9014294 RAC2 binds effectors at the plasma membrane IEA Rattus norvegicus A0A0G2K344 R-RNO-9021627 https://reactome.org/PathwayBrowser/#/R-RNO-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K344 R-RNO-9021660 https://reactome.org/PathwayBrowser/#/R-RNO-9021660 PI3K binds membrane-associated estrogen receptors IEA Rattus norvegicus A0A0G2K344 R-RNO-9027275 https://reactome.org/PathwayBrowser/#/R-RNO-9027275 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-GAB1 binds PI3K IEA Rattus norvegicus A0A0G2K344 R-RNO-912619 https://reactome.org/PathwayBrowser/#/R-RNO-912619 Cbl is tyrosine phosphorylated TAS Rattus norvegicus A0A0G2K344 R-RNO-912627 https://reactome.org/PathwayBrowser/#/R-RNO-912627 CBL ubiquitinates PI3K IEA Rattus norvegicus A0A0G2K344 R-RNO-914182 https://reactome.org/PathwayBrowser/#/R-RNO-914182 14-3-3 zeta binding allows recruitment of PI3K IEA Rattus norvegicus A0A0G2K344 R-RNO-9632412 https://reactome.org/PathwayBrowser/#/R-RNO-9632412 PTK2 is recruited to methylated ESR1 IEA Rattus norvegicus A0A0G2K344 R-RNO-9658253 https://reactome.org/PathwayBrowser/#/R-RNO-9658253 RAS:GTP binds PI3K IEA Rattus norvegicus A0A0G2K344 R-RNO-9698170 https://reactome.org/PathwayBrowser/#/R-RNO-9698170 Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA IEA Rattus norvegicus A0A0G2K344 R-RNO-9706345 https://reactome.org/PathwayBrowser/#/R-RNO-9706345 Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA IEA Rattus norvegicus A0A0G2K344 R-RNO-9842649 https://reactome.org/PathwayBrowser/#/R-RNO-9842649 Active LTK receptor binds PI3K IEA Rattus norvegicus A0A0G2K350 R-RNO-5694423 https://reactome.org/PathwayBrowser/#/R-RNO-5694423 NSF and SNAPs bind cis-SNARE complex IEA Rattus norvegicus A0A0G2K350 R-RNO-5694425 https://reactome.org/PathwayBrowser/#/R-RNO-5694425 NSF ATPase activity dissociates cis-SNARE IEA Rattus norvegicus A0A0G2K350 R-RNO-6809014 https://reactome.org/PathwayBrowser/#/R-RNO-6809014 cis-Golgi cis-SNARE binds NSF and SNAPs IEA Rattus norvegicus A0A0G2K350 R-RNO-6809015 https://reactome.org/PathwayBrowser/#/R-RNO-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Rattus norvegicus A0A0G2K350 R-RNO-6811422 https://reactome.org/PathwayBrowser/#/R-RNO-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Rattus norvegicus A0A0G2K350 R-RNO-6811425 https://reactome.org/PathwayBrowser/#/R-RNO-6811425 NSF and SNAPs bind cis-SNARE at the ER membrane IEA Rattus norvegicus A0A0G2K350 R-RNO-6814676 https://reactome.org/PathwayBrowser/#/R-RNO-6814676 SNAPs and NSF hexamer bind cis-SNARE at the TGN IEA Rattus norvegicus A0A0G2K350 R-RNO-6814683 https://reactome.org/PathwayBrowser/#/R-RNO-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN IEA Rattus norvegicus A0A0G2K350 R-RNO-6814684 https://reactome.org/PathwayBrowser/#/R-RNO-6814684 cis-SNARE binds SNAPs and NSF hexamer at the TGN IEA Rattus norvegicus A0A0G2K350 R-RNO-8847637 https://reactome.org/PathwayBrowser/#/R-RNO-8847637 NSF and SNAPs bind the cis-SNARE at the Golgi IEA Rattus norvegicus A0A0G2K350 R-RNO-8847638 https://reactome.org/PathwayBrowser/#/R-RNO-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Rattus norvegicus A0A0G2K351 R-RNO-5624130 https://reactome.org/PathwayBrowser/#/R-RNO-5624130 Myristoylated NPHP3 translocates into the ciliary membrane IEA Rattus norvegicus A0A0G2K351 R-RNO-5624131 https://reactome.org/PathwayBrowser/#/R-RNO-5624131 UNC119B binds myristoylated proteins IEA Rattus norvegicus A0A0G2K351 R-RNO-5624132 https://reactome.org/PathwayBrowser/#/R-RNO-5624132 UNC119B stimulates translocation of myristoylated ciliary cargo to the primary cilium IEA Rattus norvegicus A0A0G2K351 R-RNO-5624133 https://reactome.org/PathwayBrowser/#/R-RNO-5624133 ARL3:GTP binds the UNC119B complex IEA Rattus norvegicus A0A0G2K351 R-RNO-5638004 https://reactome.org/PathwayBrowser/#/R-RNO-5638004 RP2 binds ARL3:GTP:UNC119B IEA Rattus norvegicus A0A0G2K351 R-RNO-5638006 https://reactome.org/PathwayBrowser/#/R-RNO-5638006 ARL3 hydrolyzes GTP IEA Rattus norvegicus A0A0G2K351 R-RNO-5638007 https://reactome.org/PathwayBrowser/#/R-RNO-5638007 RP2 activates the GTPase activity of ARL3 IEA Rattus norvegicus A0A0G2K351 R-RNO-5638016 https://reactome.org/PathwayBrowser/#/R-RNO-5638016 RP2:ARL3:GDP:UNC119B dissociates IEA Rattus norvegicus A0A0G2K379 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2K390 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2K397 R-RNO-3108212 https://reactome.org/PathwayBrowser/#/R-RNO-3108212 SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 IEA Rattus norvegicus A0A0G2K3B7 R-RNO-3247837 https://reactome.org/PathwayBrowser/#/R-RNO-3247837 WNT ligands traffic to the Golgi IEA Rattus norvegicus A0A0G2K3B7 R-RNO-3247840 https://reactome.org/PathwayBrowser/#/R-RNO-3247840 WLS binds WNT ligands in the Golgi IEA Rattus norvegicus A0A0G2K3B7 R-RNO-3247843 https://reactome.org/PathwayBrowser/#/R-RNO-3247843 secretion of WNT ligands IEA Rattus norvegicus A0A0G2K3B7 R-RNO-3247844 https://reactome.org/PathwayBrowser/#/R-RNO-3247844 WNT ligands traffic to the plasma membrane IEA Rattus norvegicus A0A0G2K3B7 R-RNO-3781941 https://reactome.org/PathwayBrowser/#/R-RNO-3781941 WNTs are secreted in exosomes IEA Rattus norvegicus A0A0G2K3B7 R-RNO-3781943 https://reactome.org/PathwayBrowser/#/R-RNO-3781943 WLS:WNT complex is internalized for maturation into exosomes IEA Rattus norvegicus A0A0G2K3H0 R-RNO-1433423 https://reactome.org/PathwayBrowser/#/R-RNO-1433423 PTP-RO interacts with p-c-Kit complex IEA Rattus norvegicus A0A0G2K3H2 R-RNO-1011598 https://reactome.org/PathwayBrowser/#/R-RNO-1011598 DOCKs bind to RhoGEFs IEA Rattus norvegicus A0A0G2K3H2 R-RNO-8875576 https://reactome.org/PathwayBrowser/#/R-RNO-8875576 CRK,CRKL recruits RAC1 GEF to activated MET IEA Rattus norvegicus A0A0G2K3H2 R-RNO-8875591 https://reactome.org/PathwayBrowser/#/R-RNO-8875591 DOCK7 activates RAC1 IEA Rattus norvegicus A0A0G2K3H2 R-RNO-9013143 https://reactome.org/PathwayBrowser/#/R-RNO-9013143 RAC1 GEFs activate RAC1 IEA Rattus norvegicus A0A0G2K3H2 R-RNO-9013159 https://reactome.org/PathwayBrowser/#/R-RNO-9013159 CDC42 GEFs activate CDC42 IEA Rattus norvegicus A0A0G2K3K5 R-RNO-1964501 https://reactome.org/PathwayBrowser/#/R-RNO-1964501 Addition of galactose to Core 6 glycoprotein IEA Rattus norvegicus A0A0G2K3K5 R-RNO-2025723 https://reactome.org/PathwayBrowser/#/R-RNO-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Rattus norvegicus A0A0G2K3K5 R-RNO-2046265 https://reactome.org/PathwayBrowser/#/R-RNO-2046265 B4GALTs transfer Gal to the keratan chain IEA Rattus norvegicus A0A0G2K3K5 R-RNO-2046298 https://reactome.org/PathwayBrowser/#/R-RNO-2046298 B4GALTs transfer Gal to a branch of keratan IEA Rattus norvegicus A0A0G2K3K5 R-RNO-975919 https://reactome.org/PathwayBrowser/#/R-RNO-975919 Addition of galactose by beta 4-galactosyltransferases IEA Rattus norvegicus A0A0G2K3K5 R-RNO-9851347 https://reactome.org/PathwayBrowser/#/R-RNO-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Rattus norvegicus A0A0G2K3L5 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus A0A0G2K3L5 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus A0A0G2K3L5 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus A0A0G2K3L5 R-RNO-173626 https://reactome.org/PathwayBrowser/#/R-RNO-173626 Activation of C1r IEA Rattus norvegicus A0A0G2K3L5 R-RNO-173631 https://reactome.org/PathwayBrowser/#/R-RNO-173631 Activation of C1s IEA Rattus norvegicus A0A0G2K3L5 R-RNO-1861621 https://reactome.org/PathwayBrowser/#/R-RNO-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K3L5 R-RNO-199161 https://reactome.org/PathwayBrowser/#/R-RNO-199161 Fc gamma receptors interact with antigen-bound IgG IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2029268 https://reactome.org/PathwayBrowser/#/R-RNO-2029268 Phosphorylation and activation of PLCG IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2029270 https://reactome.org/PathwayBrowser/#/R-RNO-2029270 Recruitment of PLCgamma to membrane IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2029272 https://reactome.org/PathwayBrowser/#/R-RNO-2029272 Release of PLCG from FCGR IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2029273 https://reactome.org/PathwayBrowser/#/R-RNO-2029273 PI3K binds to p-6Y-SYK IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2029451 https://reactome.org/PathwayBrowser/#/R-RNO-2029451 Activation of RAC1 by VAV IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2029452 https://reactome.org/PathwayBrowser/#/R-RNO-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2029453 https://reactome.org/PathwayBrowser/#/R-RNO-2029453 Phosphorylation of VAV IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2029455 https://reactome.org/PathwayBrowser/#/R-RNO-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2029457 https://reactome.org/PathwayBrowser/#/R-RNO-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2029458 https://reactome.org/PathwayBrowser/#/R-RNO-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2029459 https://reactome.org/PathwayBrowser/#/R-RNO-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2029467 https://reactome.org/PathwayBrowser/#/R-RNO-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2029476 https://reactome.org/PathwayBrowser/#/R-RNO-2029476 Role of myosins in phagosome formation IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2203516 https://reactome.org/PathwayBrowser/#/R-RNO-2203516 Alpha-1-Microglobulin is cleaved IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2454192 https://reactome.org/PathwayBrowser/#/R-RNO-2454192 Allergen dependent IgE bound FCERI aggregation IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2454208 https://reactome.org/PathwayBrowser/#/R-RNO-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2454240 https://reactome.org/PathwayBrowser/#/R-RNO-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2730843 https://reactome.org/PathwayBrowser/#/R-RNO-2730843 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2730851 https://reactome.org/PathwayBrowser/#/R-RNO-2730851 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2730882 https://reactome.org/PathwayBrowser/#/R-RNO-2730882 Phosphorylation of PKC-theta IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2730884 https://reactome.org/PathwayBrowser/#/R-RNO-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Rattus norvegicus A0A0G2K3L5 R-RNO-2730886 https://reactome.org/PathwayBrowser/#/R-RNO-2730886 Phosphorylation of SHC by SYK kinase IEA Rattus norvegicus A0A0G2K3L5 R-RNO-5690701 https://reactome.org/PathwayBrowser/#/R-RNO-5690701 SHP1 binds p-CD22 IEA Rattus norvegicus A0A0G2K3L5 R-RNO-5690702 https://reactome.org/PathwayBrowser/#/R-RNO-5690702 LYN phosphorylates CD22 IEA Rattus norvegicus A0A0G2K3L5 R-RNO-5690740 https://reactome.org/PathwayBrowser/#/R-RNO-5690740 CD22 binds B-cell receptor IEA Rattus norvegicus A0A0G2K3L5 R-RNO-8852266 https://reactome.org/PathwayBrowser/#/R-RNO-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Rattus norvegicus A0A0G2K3L5 R-RNO-8852481 https://reactome.org/PathwayBrowser/#/R-RNO-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Rattus norvegicus A0A0G2K3L5 R-RNO-8858428 https://reactome.org/PathwayBrowser/#/R-RNO-8858428 FCAMR binds IgA IEA Rattus norvegicus A0A0G2K3L5 R-RNO-9021306 https://reactome.org/PathwayBrowser/#/R-RNO-9021306 C1-Inh binds and inactivates C1r, C1s IEA Rattus norvegicus A0A0G2K3L5 R-RNO-9606151 https://reactome.org/PathwayBrowser/#/R-RNO-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Rattus norvegicus A0A0G2K3L5 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus A0A0G2K3L5 R-RNO-9724685 https://reactome.org/PathwayBrowser/#/R-RNO-9724685 IgE binds omalizumab IEA Rattus norvegicus A0A0G2K3L5 R-RNO-9725206 https://reactome.org/PathwayBrowser/#/R-RNO-9725206 IgE binds FCERI IEA Rattus norvegicus A0A0G2K3L5 R-RNO-983696 https://reactome.org/PathwayBrowser/#/R-RNO-983696 The Immunoglobulin of the BCR binds antigen IEA Rattus norvegicus A0A0G2K3L5 R-RNO-983700 https://reactome.org/PathwayBrowser/#/R-RNO-983700 SYK binds the activated BCR IEA Rattus norvegicus A0A0G2K3L5 R-RNO-983703 https://reactome.org/PathwayBrowser/#/R-RNO-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Rattus norvegicus A0A0G2K3L5 R-RNO-983707 https://reactome.org/PathwayBrowser/#/R-RNO-983707 SYK autophosphorylates at the activated BCR IEA Rattus norvegicus A0A0G2K3M4 R-RNO-111439 https://reactome.org/PathwayBrowser/#/R-RNO-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Rattus norvegicus A0A0G2K3M4 R-RNO-141409 https://reactome.org/PathwayBrowser/#/R-RNO-141409 Mad1 binds kinetochore IEA Rattus norvegicus A0A0G2K3M4 R-RNO-141422 https://reactome.org/PathwayBrowser/#/R-RNO-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Rattus norvegicus A0A0G2K3M4 R-RNO-141431 https://reactome.org/PathwayBrowser/#/R-RNO-141431 MAD2 associates with the Mad1 kinetochore complex IEA Rattus norvegicus A0A0G2K3M4 R-RNO-141439 https://reactome.org/PathwayBrowser/#/R-RNO-141439 Release of activated MAD2 from kinetochores IEA Rattus norvegicus A0A0G2K3M4 R-RNO-158441 https://reactome.org/PathwayBrowser/#/R-RNO-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Rattus norvegicus A0A0G2K3M4 R-RNO-158447 https://reactome.org/PathwayBrowser/#/R-RNO-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Rattus norvegicus A0A0G2K3M4 R-RNO-158481 https://reactome.org/PathwayBrowser/#/R-RNO-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Rattus norvegicus A0A0G2K3M4 R-RNO-158484 https://reactome.org/PathwayBrowser/#/R-RNO-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Rattus norvegicus A0A0G2K3M4 R-RNO-159046 https://reactome.org/PathwayBrowser/#/R-RNO-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Rattus norvegicus A0A0G2K3M4 R-RNO-159050 https://reactome.org/PathwayBrowser/#/R-RNO-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Rattus norvegicus A0A0G2K3M4 R-RNO-1638803 https://reactome.org/PathwayBrowser/#/R-RNO-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Rattus norvegicus A0A0G2K3M4 R-RNO-1638821 https://reactome.org/PathwayBrowser/#/R-RNO-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Rattus norvegicus A0A0G2K3M4 R-RNO-170796 https://reactome.org/PathwayBrowser/#/R-RNO-170796 NPC transports GCK1:GKRP from cytosol to nucleoplasm IEA Rattus norvegicus A0A0G2K3M4 R-RNO-170825 https://reactome.org/PathwayBrowser/#/R-RNO-170825 NPC exports GCK1 from nucleus IEA Rattus norvegicus A0A0G2K3M4 R-RNO-191830 https://reactome.org/PathwayBrowser/#/R-RNO-191830 snRNP nuclear import and release IEA Rattus norvegicus A0A0G2K3M4 R-RNO-2467809 https://reactome.org/PathwayBrowser/#/R-RNO-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Rattus norvegicus A0A0G2K3M4 R-RNO-2467811 https://reactome.org/PathwayBrowser/#/R-RNO-2467811 Separation of sister chromatids IEA Rattus norvegicus A0A0G2K3M4 R-RNO-2468287 https://reactome.org/PathwayBrowser/#/R-RNO-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Rattus norvegicus A0A0G2K3M4 R-RNO-2484822 https://reactome.org/PathwayBrowser/#/R-RNO-2484822 Kinetochore assembly IEA Rattus norvegicus A0A0G2K3M4 R-RNO-2990882 https://reactome.org/PathwayBrowser/#/R-RNO-2990882 CDK1 phosphorylates NUP98 IEA Rattus norvegicus A0A0G2K3M4 R-RNO-3000348 https://reactome.org/PathwayBrowser/#/R-RNO-3000348 RANBP2 SUMOylates SP100 with SUMO2 IEA Rattus norvegicus A0A0G2K3M4 R-RNO-3000399 https://reactome.org/PathwayBrowser/#/R-RNO-3000399 RANBP2 SUMOylates SP100 with SUMO1 IEA Rattus norvegicus A0A0G2K3M4 R-RNO-3000411 https://reactome.org/PathwayBrowser/#/R-RNO-3000411 RANBP2 SUMOylates PML with SUMO2 IEA Rattus norvegicus A0A0G2K3M4 R-RNO-375302 https://reactome.org/PathwayBrowser/#/R-RNO-375302 Kinetochore capture of astral microtubules IEA Rattus norvegicus A0A0G2K3M4 R-RNO-4551649 https://reactome.org/PathwayBrowser/#/R-RNO-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Rattus norvegicus A0A0G2K3M4 R-RNO-4551679 https://reactome.org/PathwayBrowser/#/R-RNO-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Rattus norvegicus A0A0G2K3M4 R-RNO-4570493 https://reactome.org/PathwayBrowser/#/R-RNO-4570493 RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 IEA Rattus norvegicus A0A0G2K3M4 R-RNO-4615872 https://reactome.org/PathwayBrowser/#/R-RNO-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Rattus norvegicus A0A0G2K3M4 R-RNO-4615987 https://reactome.org/PathwayBrowser/#/R-RNO-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Rattus norvegicus A0A0G2K3M4 R-RNO-4655355 https://reactome.org/PathwayBrowser/#/R-RNO-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Rattus norvegicus A0A0G2K3M4 R-RNO-5228508 https://reactome.org/PathwayBrowser/#/R-RNO-5228508 RANBP2 SUMOylates PML with SUMO1 IEA Rattus norvegicus A0A0G2K3M4 R-RNO-5228523 https://reactome.org/PathwayBrowser/#/R-RNO-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Rattus norvegicus A0A0G2K3M4 R-RNO-5252041 https://reactome.org/PathwayBrowser/#/R-RNO-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Rattus norvegicus A0A0G2K3M4 R-RNO-5578744 https://reactome.org/PathwayBrowser/#/R-RNO-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Rattus norvegicus A0A0G2K3M4 R-RNO-5666129 https://reactome.org/PathwayBrowser/#/R-RNO-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Rattus norvegicus A0A0G2K3M4 R-RNO-5666160 https://reactome.org/PathwayBrowser/#/R-RNO-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Rattus norvegicus A0A0G2K3M4 R-RNO-5666169 https://reactome.org/PathwayBrowser/#/R-RNO-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Rattus norvegicus A0A0G2K3M4 R-RNO-75097 https://reactome.org/PathwayBrowser/#/R-RNO-75097 Transport of the export-competent mRNP complex through the NPC IEA Rattus norvegicus A0A0G2K3M4 R-RNO-75098 https://reactome.org/PathwayBrowser/#/R-RNO-75098 mRNP complex dissociates from cytosolic face of NPC IEA Rattus norvegicus A0A0G2K3M4 R-RNO-77587 https://reactome.org/PathwayBrowser/#/R-RNO-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Rattus norvegicus A0A0G2K3M4 R-RNO-77594 https://reactome.org/PathwayBrowser/#/R-RNO-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Rattus norvegicus A0A0G2K3M4 R-RNO-9615901 https://reactome.org/PathwayBrowser/#/R-RNO-9615901 AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex IEA Rattus norvegicus A0A0G2K3M4 R-RNO-9618378 https://reactome.org/PathwayBrowser/#/R-RNO-9618378 POM121 binds the Nup107-Nup160 complex IEA Rattus norvegicus A0A0G2K3M4 R-RNO-9634169 https://reactome.org/PathwayBrowser/#/R-RNO-9634169 POM121 and NDC1 bind the Nup93 complex IEA Rattus norvegicus A0A0G2K3M4 R-RNO-9648114 https://reactome.org/PathwayBrowser/#/R-RNO-9648114 EML4 recruits NUDC to mitotic spindle IEA Rattus norvegicus A0A0G2K3N6 R-RNO-4754181 https://reactome.org/PathwayBrowser/#/R-RNO-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Rattus norvegicus A0A0G2K3N6 R-RNO-5661116 https://reactome.org/PathwayBrowser/#/R-RNO-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Rattus norvegicus A0A0G2K3N6 R-RNO-8865265 https://reactome.org/PathwayBrowser/#/R-RNO-8865265 TFAP2C homodimer binds MYC and KDM5B IEA Rattus norvegicus A0A0G2K3R4 R-RNO-8956568 https://reactome.org/PathwayBrowser/#/R-RNO-8956568 RUNX1 binds the core TAL1 complex IEA Rattus norvegicus A0A0G2K3S4 R-RNO-1369028 https://reactome.org/PathwayBrowser/#/R-RNO-1369028 ABCAs mediate lipid efflux IEA Rattus norvegicus A0A0G2K3S4 R-RNO-1369052 https://reactome.org/PathwayBrowser/#/R-RNO-1369052 ABCAs mediate lipid influx IEA Rattus norvegicus A0A0G2K3S9 R-RNO-425678 https://reactome.org/PathwayBrowser/#/R-RNO-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Rattus norvegicus A0A0G2K3T8 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2K3T8 R-RNO-9842833 https://reactome.org/PathwayBrowser/#/R-RNO-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Rattus norvegicus A0A0G2K3T8 R-RNO-9842835 https://reactome.org/PathwayBrowser/#/R-RNO-9842835 KRAB-ZFP binds retroelement DNA in chromatin IEA Rattus norvegicus A0A0G2K3T8 R-RNO-9842839 https://reactome.org/PathwayBrowser/#/R-RNO-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Rattus norvegicus A0A0G2K3T8 R-RNO-9843978 https://reactome.org/PathwayBrowser/#/R-RNO-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Rattus norvegicus A0A0G2K3W8 R-RNO-5635854 https://reactome.org/PathwayBrowser/#/R-RNO-5635854 GLI2,3 are degraded by the proteasome IEA Rattus norvegicus A0A0G2K3W8 R-RNO-5635855 https://reactome.org/PathwayBrowser/#/R-RNO-5635855 phosphorylated GLI proteins bind SPOP:CUL3:RBX1 IEA Rattus norvegicus A0A0G2K3W8 R-RNO-5635856 https://reactome.org/PathwayBrowser/#/R-RNO-5635856 SPOP:CUL3:RBX1 ubiquitinates GLI2,3 IEA Rattus norvegicus A0A0G2K410 R-RNO-5229111 https://reactome.org/PathwayBrowser/#/R-RNO-5229111 AP4 transports APP from trans-Golgi network to endosome lumen IEA Rattus norvegicus A0A0G2K410 R-RNO-5229132 https://reactome.org/PathwayBrowser/#/R-RNO-5229132 AP4 binds APP IEA Rattus norvegicus A0A0G2K430 R-RNO-6789310 https://reactome.org/PathwayBrowser/#/R-RNO-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Rattus norvegicus A0A0G2K437 R-RNO-8850594 https://reactome.org/PathwayBrowser/#/R-RNO-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Rattus norvegicus A0A0G2K470 R-RNO-2327695 https://reactome.org/PathwayBrowser/#/R-RNO-2327695 Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 IEA Rattus norvegicus A0A0G2K470 R-RNO-2681667 https://reactome.org/PathwayBrowser/#/R-RNO-2681667 TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 IEA Rattus norvegicus A0A0G2K470 R-RNO-2731074 https://reactome.org/PathwayBrowser/#/R-RNO-2731074 Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) IEA Rattus norvegicus A0A0G2K470 R-RNO-4085133 https://reactome.org/PathwayBrowser/#/R-RNO-4085133 LUM (lumican) binds integrin alpha2beta1 IEA Rattus norvegicus A0A0G2K470 R-RNO-4086216 https://reactome.org/PathwayBrowser/#/R-RNO-4086216 Collagen type VII binds integrin alpha2beta1 IEA Rattus norvegicus A0A0G2K470 R-RNO-8874079 https://reactome.org/PathwayBrowser/#/R-RNO-8874079 PTK2 binds activated MET IEA Rattus norvegicus A0A0G2K475 R-RNO-5684875 https://reactome.org/PathwayBrowser/#/R-RNO-5684875 Binding of ATR:ATRIP to RPA at resected DNA DSBs IEA Rattus norvegicus A0A0G2K475 R-RNO-5684882 https://reactome.org/PathwayBrowser/#/R-RNO-5684882 CHEK1 is recruited to resected DNA DSBs IEA Rattus norvegicus A0A0G2K475 R-RNO-5684887 https://reactome.org/PathwayBrowser/#/R-RNO-5684887 Activation of CHEK1 at resected DNA DSBs IEA Rattus norvegicus A0A0G2K475 R-RNO-5685011 https://reactome.org/PathwayBrowser/#/R-RNO-5685011 ATR activation at DNA DSBs IEA Rattus norvegicus A0A0G2K475 R-RNO-5685156 https://reactome.org/PathwayBrowser/#/R-RNO-5685156 ATR phosphorylates RPA2 IEA Rattus norvegicus A0A0G2K475 R-RNO-5685341 https://reactome.org/PathwayBrowser/#/R-RNO-5685341 BCDX2 complex stabilizes RAD51 filament IEA Rattus norvegicus A0A0G2K475 R-RNO-5685838 https://reactome.org/PathwayBrowser/#/R-RNO-5685838 CX3 complex binds D-loop structures IEA Rattus norvegicus A0A0G2K475 R-RNO-5685985 https://reactome.org/PathwayBrowser/#/R-RNO-5685985 EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment IEA Rattus norvegicus A0A0G2K475 R-RNO-5685994 https://reactome.org/PathwayBrowser/#/R-RNO-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Rattus norvegicus A0A0G2K475 R-RNO-5686440 https://reactome.org/PathwayBrowser/#/R-RNO-5686440 MUS81:EME1,EME2 cleaves D-loop IEA Rattus norvegicus A0A0G2K475 R-RNO-5686642 https://reactome.org/PathwayBrowser/#/R-RNO-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Rattus norvegicus A0A0G2K475 R-RNO-5686657 https://reactome.org/PathwayBrowser/#/R-RNO-5686657 ERCC1:XPF cleaves flaps generated by SSA IEA Rattus norvegicus A0A0G2K475 R-RNO-5693539 https://reactome.org/PathwayBrowser/#/R-RNO-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Rattus norvegicus A0A0G2K475 R-RNO-5693542 https://reactome.org/PathwayBrowser/#/R-RNO-5693542 Association of RPA complexes with ssDNA at resected DNA DSBs IEA Rattus norvegicus A0A0G2K475 R-RNO-5693564 https://reactome.org/PathwayBrowser/#/R-RNO-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Rattus norvegicus A0A0G2K475 R-RNO-5693580 https://reactome.org/PathwayBrowser/#/R-RNO-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Rattus norvegicus A0A0G2K475 R-RNO-5693584 https://reactome.org/PathwayBrowser/#/R-RNO-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Rattus norvegicus A0A0G2K475 R-RNO-5693593 https://reactome.org/PathwayBrowser/#/R-RNO-5693593 D-loop extension by DNA polymerases IEA Rattus norvegicus A0A0G2K475 R-RNO-5693620 https://reactome.org/PathwayBrowser/#/R-RNO-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Rattus norvegicus A0A0G2K475 R-RNO-6799332 https://reactome.org/PathwayBrowser/#/R-RNO-6799332 ATR phosphorylates TP53 IEA Rattus norvegicus A0A0G2K475 R-RNO-9853389 https://reactome.org/PathwayBrowser/#/R-RNO-9853389 FIGNL1 binds RAD51 IEA Rattus norvegicus A0A0G2K478 R-RNO-74207 https://reactome.org/PathwayBrowser/#/R-RNO-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Rattus norvegicus A0A0G2K490 R-RNO-3225851 https://reactome.org/PathwayBrowser/#/R-RNO-3225851 ROS oxidize thioredoxin and activate MAP3K5 IEA Rattus norvegicus A0A0G2K492 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2K4A8 R-RNO-2028555 https://reactome.org/PathwayBrowser/#/R-RNO-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Rattus norvegicus A0A0G2K4A8 R-RNO-2028583 https://reactome.org/PathwayBrowser/#/R-RNO-2028583 Phosphorylation of YAP by LATS2 IEA Rattus norvegicus A0A0G2K4A8 R-RNO-2028589 https://reactome.org/PathwayBrowser/#/R-RNO-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Rattus norvegicus A0A0G2K4A8 R-RNO-2028626 https://reactome.org/PathwayBrowser/#/R-RNO-2028626 Phosphorylated MOB1A proteins associate with LATS proteins IEA Rattus norvegicus A0A0G2K4A8 R-RNO-2028661 https://reactome.org/PathwayBrowser/#/R-RNO-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Rattus norvegicus A0A0G2K4A8 R-RNO-2028673 https://reactome.org/PathwayBrowser/#/R-RNO-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Rattus norvegicus A0A0G2K4A8 R-RNO-2028679 https://reactome.org/PathwayBrowser/#/R-RNO-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Rattus norvegicus A0A0G2K4A8 R-RNO-2038398 https://reactome.org/PathwayBrowser/#/R-RNO-2038398 KIBRA (WWC1) binds LATS proteins IEA Rattus norvegicus A0A0G2K4A8 R-RNO-2059926 https://reactome.org/PathwayBrowser/#/R-RNO-2059926 NPHP4 protein binds LATS proteins IEA Rattus norvegicus A0A0G2K4C0 R-RNO-1889981 https://reactome.org/PathwayBrowser/#/R-RNO-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Rattus norvegicus A0A0G2K4D9 R-RNO-1638803 https://reactome.org/PathwayBrowser/#/R-RNO-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Rattus norvegicus A0A0G2K4D9 R-RNO-1638821 https://reactome.org/PathwayBrowser/#/R-RNO-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Rattus norvegicus A0A0G2K4D9 R-RNO-2466068 https://reactome.org/PathwayBrowser/#/R-RNO-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Rattus norvegicus A0A0G2K4D9 R-RNO-2467794 https://reactome.org/PathwayBrowser/#/R-RNO-2467794 Resolution of sister chromatids IEA Rattus norvegicus A0A0G2K4D9 R-RNO-2467809 https://reactome.org/PathwayBrowser/#/R-RNO-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Rattus norvegicus A0A0G2K4D9 R-RNO-2467811 https://reactome.org/PathwayBrowser/#/R-RNO-2467811 Separation of sister chromatids IEA Rattus norvegicus A0A0G2K4D9 R-RNO-2468039 https://reactome.org/PathwayBrowser/#/R-RNO-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Rattus norvegicus A0A0G2K4D9 R-RNO-2468040 https://reactome.org/PathwayBrowser/#/R-RNO-2468040 Cohesin binds PDS5 and WAPAL IEA Rattus norvegicus A0A0G2K4D9 R-RNO-2468041 https://reactome.org/PathwayBrowser/#/R-RNO-2468041 CDCA5 (Sororin) enables cohesion of sister chromosomal arms IEA Rattus norvegicus A0A0G2K4D9 R-RNO-2468287 https://reactome.org/PathwayBrowser/#/R-RNO-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Rattus norvegicus A0A0G2K4D9 R-RNO-2468293 https://reactome.org/PathwayBrowser/#/R-RNO-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Rattus norvegicus A0A0G2K4D9 R-RNO-2470935 https://reactome.org/PathwayBrowser/#/R-RNO-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Rattus norvegicus A0A0G2K4D9 R-RNO-2473151 https://reactome.org/PathwayBrowser/#/R-RNO-2473151 CDCA5 (Sororin) enables cohesion of sister centromeres IEA Rattus norvegicus A0A0G2K4D9 R-RNO-2473152 https://reactome.org/PathwayBrowser/#/R-RNO-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Rattus norvegicus A0A0G2K4D9 R-RNO-2484822 https://reactome.org/PathwayBrowser/#/R-RNO-2484822 Kinetochore assembly IEA Rattus norvegicus A0A0G2K4D9 R-RNO-2545203 https://reactome.org/PathwayBrowser/#/R-RNO-2545203 Deacetylation of cleaved cohesin IEA Rattus norvegicus A0A0G2K4D9 R-RNO-2545253 https://reactome.org/PathwayBrowser/#/R-RNO-2545253 Deacetylation of cohesin IEA Rattus norvegicus A0A0G2K4D9 R-RNO-3108212 https://reactome.org/PathwayBrowser/#/R-RNO-3108212 SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 IEA Rattus norvegicus A0A0G2K4H7 R-RNO-6805546 https://reactome.org/PathwayBrowser/#/R-RNO-6805546 Keratin type I binds keratin type II IEA Rattus norvegicus A0A0G2K4H7 R-RNO-6805573 https://reactome.org/PathwayBrowser/#/R-RNO-6805573 Keratin type I/type II heterodimers form tetramers IEA Rattus norvegicus A0A0G2K4H7 R-RNO-6806610 https://reactome.org/PathwayBrowser/#/R-RNO-6806610 Keratin filament formation IEA Rattus norvegicus A0A0G2K4H7 R-RNO-6806613 https://reactome.org/PathwayBrowser/#/R-RNO-6806613 Keratin tetramers bind to form unit length filaments IEA Rattus norvegicus A0A0G2K4H7 R-RNO-6806629 https://reactome.org/PathwayBrowser/#/R-RNO-6806629 Formation of tonofilament bundles IEA Rattus norvegicus A0A0G2K4H7 R-RNO-6809393 https://reactome.org/PathwayBrowser/#/R-RNO-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Rattus norvegicus A0A0G2K4H7 R-RNO-6809663 https://reactome.org/PathwayBrowser/#/R-RNO-6809663 Formation of hair keratin fibres IEA Rattus norvegicus A0A0G2K4H7 R-RNO-6810357 https://reactome.org/PathwayBrowser/#/R-RNO-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Rattus norvegicus A0A0G2K4H7 R-RNO-6810937 https://reactome.org/PathwayBrowser/#/R-RNO-6810937 Lamellar bodies bind the early cornified envelope IEA Rattus norvegicus A0A0G2K4H7 R-RNO-6814387 https://reactome.org/PathwayBrowser/#/R-RNO-6814387 CASP14 cleaves filaggrin IEA Rattus norvegicus A0A0G2K4H7 R-RNO-6814734 https://reactome.org/PathwayBrowser/#/R-RNO-6814734 CDSN binds the cornified envelope IEA Rattus norvegicus A0A0G2K4H7 R-RNO-6814764 https://reactome.org/PathwayBrowser/#/R-RNO-6814764 Plasma membrane resorption IEA Rattus norvegicus A0A0G2K4I9 R-RNO-158145 https://reactome.org/PathwayBrowser/#/R-RNO-158145 factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex IEA Rattus norvegicus A0A0G2K4I9 R-RNO-158300 https://reactome.org/PathwayBrowser/#/R-RNO-158300 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (XIIa catalyst) IEA Rattus norvegicus A0A0G2K4I9 R-RNO-158333 https://reactome.org/PathwayBrowser/#/R-RNO-158333 factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) IEA Rattus norvegicus A0A0G2K4I9 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus A0A0G2K4L7 R-RNO-5653754 https://reactome.org/PathwayBrowser/#/R-RNO-5653754 UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA IEA Rattus norvegicus A0A0G2K4L7 R-RNO-5653756 https://reactome.org/PathwayBrowser/#/R-RNO-5653756 TRIM25 binds monoUb:164-PCNA IEA Rattus norvegicus A0A0G2K4L7 R-RNO-5653766 https://reactome.org/PathwayBrowser/#/R-RNO-5653766 USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Rattus norvegicus A0A0G2K4L7 R-RNO-5653770 https://reactome.org/PathwayBrowser/#/R-RNO-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Rattus norvegicus A0A0G2K4L7 R-RNO-5655835 https://reactome.org/PathwayBrowser/#/R-RNO-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Rattus norvegicus A0A0G2K4L7 R-RNO-5655892 https://reactome.org/PathwayBrowser/#/R-RNO-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Rattus norvegicus A0A0G2K4L7 R-RNO-5655965 https://reactome.org/PathwayBrowser/#/R-RNO-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Rattus norvegicus A0A0G2K4L7 R-RNO-5690213 https://reactome.org/PathwayBrowser/#/R-RNO-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Rattus norvegicus A0A0G2K4L7 R-RNO-5690988 https://reactome.org/PathwayBrowser/#/R-RNO-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Rattus norvegicus A0A0G2K4L7 R-RNO-5691001 https://reactome.org/PathwayBrowser/#/R-RNO-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Rattus norvegicus A0A0G2K4L7 R-RNO-5693593 https://reactome.org/PathwayBrowser/#/R-RNO-5693593 D-loop extension by DNA polymerases IEA Rattus norvegicus A0A0G2K4L7 R-RNO-6782208 https://reactome.org/PathwayBrowser/#/R-RNO-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Rattus norvegicus A0A0G2K4L7 R-RNO-6782211 https://reactome.org/PathwayBrowser/#/R-RNO-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Rattus norvegicus A0A0G2K4L7 R-RNO-6782224 https://reactome.org/PathwayBrowser/#/R-RNO-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Rattus norvegicus A0A0G2K4L7 R-RNO-6782227 https://reactome.org/PathwayBrowser/#/R-RNO-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Rattus norvegicus A0A0G2K4P1 R-RNO-5631903 https://reactome.org/PathwayBrowser/#/R-RNO-5631903 SESN1,2,3 bind overoxidized PRDX1 IEA Rattus norvegicus A0A0G2K4P1 R-RNO-5631941 https://reactome.org/PathwayBrowser/#/R-RNO-5631941 SESN1,2,3 bind AMPK IEA Rattus norvegicus A0A0G2K4P1 R-RNO-9639287 https://reactome.org/PathwayBrowser/#/R-RNO-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Rattus norvegicus A0A0G2K4P1 R-RNO-9640195 https://reactome.org/PathwayBrowser/#/R-RNO-9640195 RRAGA,B hydrolyzes GTP IEA Rattus norvegicus A0A0G2K4P1 R-RNO-9766645 https://reactome.org/PathwayBrowser/#/R-RNO-9766645 CUL3:RBX1 ubiquitinates KEAP1 IEA Rattus norvegicus A0A0G2K4P1 R-RNO-9766656 https://reactome.org/PathwayBrowser/#/R-RNO-9766656 RBX1:CUL3 dissociates from forming autophagosome IEA Rattus norvegicus A0A0G2K4P1 R-RNO-9766677 https://reactome.org/PathwayBrowser/#/R-RNO-9766677 MAP1LC3B binds KEAP1 and SQSTM1 IEA Rattus norvegicus A0A0G2K4P1 R-RNO-9766687 https://reactome.org/PathwayBrowser/#/R-RNO-9766687 SESN1,SESN1 bind SQSTM1 and KEAP1 IEA Rattus norvegicus A0A0G2K4P5 R-RNO-9770236 https://reactome.org/PathwayBrowser/#/R-RNO-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Rattus norvegicus A0A0G2K4R2 R-RNO-174931 https://reactome.org/PathwayBrowser/#/R-RNO-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Rattus norvegicus A0A0G2K4S5 R-RNO-1236943 https://reactome.org/PathwayBrowser/#/R-RNO-1236943 Loading of antigen peptide onto MHC class I molecule IEA Rattus norvegicus A0A0G2K4S5 R-RNO-1236954 https://reactome.org/PathwayBrowser/#/R-RNO-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Rattus norvegicus A0A0G2K4S5 R-RNO-1236964 https://reactome.org/PathwayBrowser/#/R-RNO-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Rattus norvegicus A0A0G2K4S5 R-RNO-1236965 https://reactome.org/PathwayBrowser/#/R-RNO-1236965 Export of peptide loaded MHC class I complex to PM IEA Rattus norvegicus A0A0G2K4S5 R-RNO-198955 https://reactome.org/PathwayBrowser/#/R-RNO-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Rattus norvegicus A0A0G2K4S5 R-RNO-198958 https://reactome.org/PathwayBrowser/#/R-RNO-198958 KIR2DL2/3 interacting with HLA-C group 1 (Cw4) IEA Rattus norvegicus A0A0G2K4S5 R-RNO-199169 https://reactome.org/PathwayBrowser/#/R-RNO-199169 MHC Class I interacts with CD160 IEA Rattus norvegicus A0A0G2K4S5 R-RNO-199558 https://reactome.org/PathwayBrowser/#/R-RNO-199558 KIR2DL1 interacting with HLA-C group 2 (Cw3) IEA Rattus norvegicus A0A0G2K4S5 R-RNO-199566 https://reactome.org/PathwayBrowser/#/R-RNO-199566 KIR3DL1 interacting with HLA Bw4 IEA Rattus norvegicus A0A0G2K4S5 R-RNO-199583 https://reactome.org/PathwayBrowser/#/R-RNO-199583 KIR2DS2 interacting with HLA-C group 1 (Cw3) IEA Rattus norvegicus A0A0G2K4S5 R-RNO-199587 https://reactome.org/PathwayBrowser/#/R-RNO-199587 KIR2DS1 interacting with HLA-C group 2 (Cw4) IEA Rattus norvegicus A0A0G2K4S5 R-RNO-210298 https://reactome.org/PathwayBrowser/#/R-RNO-210298 Interaction of DAP12 and KIR3DS1 IEA Rattus norvegicus A0A0G2K4S5 R-RNO-210309 https://reactome.org/PathwayBrowser/#/R-RNO-210309 Interaction of DAP12 and KIR2DS2 IEA Rattus norvegicus A0A0G2K4S5 R-RNO-2272753 https://reactome.org/PathwayBrowser/#/R-RNO-2272753 Interaction of DAP12 and KIR2DS4 IEA Rattus norvegicus A0A0G2K4S5 R-RNO-2272795 https://reactome.org/PathwayBrowser/#/R-RNO-2272795 Interaction of DAP12 and KIR2DS1 IEA Rattus norvegicus A0A0G2K4S5 R-RNO-6798739 https://reactome.org/PathwayBrowser/#/R-RNO-6798739 Exocytosis of azurophil granule membrane proteins IEA Rattus norvegicus A0A0G2K4S5 R-RNO-6798743 https://reactome.org/PathwayBrowser/#/R-RNO-6798743 Exocytosis of secretory granule membrane proteins IEA Rattus norvegicus A0A0G2K4S5 R-RNO-8863973 https://reactome.org/PathwayBrowser/#/R-RNO-8863973 Fusion of ERC and phagosome IEA Rattus norvegicus A0A0G2K4S5 R-RNO-8951499 https://reactome.org/PathwayBrowser/#/R-RNO-8951499 Loading of antigenic peptides on to class I MHC IEA Rattus norvegicus A0A0G2K4S5 R-RNO-983138 https://reactome.org/PathwayBrowser/#/R-RNO-983138 Transport of MHC heterotrimer to ER exit site IEA Rattus norvegicus A0A0G2K4S5 R-RNO-983142 https://reactome.org/PathwayBrowser/#/R-RNO-983142 Formation of peptide loading complex (PLC) IEA Rattus norvegicus A0A0G2K4S5 R-RNO-983145 https://reactome.org/PathwayBrowser/#/R-RNO-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Rattus norvegicus A0A0G2K4S5 R-RNO-983146 https://reactome.org/PathwayBrowser/#/R-RNO-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Rattus norvegicus A0A0G2K4S5 R-RNO-983161 https://reactome.org/PathwayBrowser/#/R-RNO-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex IEA Rattus norvegicus A0A0G2K4S5 R-RNO-983421 https://reactome.org/PathwayBrowser/#/R-RNO-983421 Journey of cargo through Golgi complex IEA Rattus norvegicus A0A0G2K4S5 R-RNO-983422 https://reactome.org/PathwayBrowser/#/R-RNO-983422 Disassembly of COPII coated vesicle IEA Rattus norvegicus A0A0G2K4S5 R-RNO-983424 https://reactome.org/PathwayBrowser/#/R-RNO-983424 Budding of COPII coated vesicle IEA Rattus norvegicus A0A0G2K4S5 R-RNO-983425 https://reactome.org/PathwayBrowser/#/R-RNO-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Rattus norvegicus A0A0G2K4S5 R-RNO-983427 https://reactome.org/PathwayBrowser/#/R-RNO-983427 Expression of peptide bound class I MHC on cell surface IEA Rattus norvegicus A0A0G2K4S7 R-RNO-5696465 https://reactome.org/PathwayBrowser/#/R-RNO-5696465 USP45 deubiquitinates ERCC1 IEA Rattus norvegicus A0A0G2K4T5 R-RNO-3108212 https://reactome.org/PathwayBrowser/#/R-RNO-3108212 SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 IEA Rattus norvegicus A0A0G2K4T6 R-RNO-5336453 https://reactome.org/PathwayBrowser/#/R-RNO-5336453 NIPAs transport Mg2+ from extracellular region to cytosol IEA Rattus norvegicus A0A0G2K4W1 R-RNO-6809663 https://reactome.org/PathwayBrowser/#/R-RNO-6809663 Formation of hair keratin fibres IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5358597 https://reactome.org/PathwayBrowser/#/R-RNO-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5358599 https://reactome.org/PathwayBrowser/#/R-RNO-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5684875 https://reactome.org/PathwayBrowser/#/R-RNO-5684875 Binding of ATR:ATRIP to RPA at resected DNA DSBs IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5684882 https://reactome.org/PathwayBrowser/#/R-RNO-5684882 CHEK1 is recruited to resected DNA DSBs IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5684887 https://reactome.org/PathwayBrowser/#/R-RNO-5684887 Activation of CHEK1 at resected DNA DSBs IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5685011 https://reactome.org/PathwayBrowser/#/R-RNO-5685011 ATR activation at DNA DSBs IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5685156 https://reactome.org/PathwayBrowser/#/R-RNO-5685156 ATR phosphorylates RPA2 IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5685341 https://reactome.org/PathwayBrowser/#/R-RNO-5685341 BCDX2 complex stabilizes RAD51 filament IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5685838 https://reactome.org/PathwayBrowser/#/R-RNO-5685838 CX3 complex binds D-loop structures IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5685985 https://reactome.org/PathwayBrowser/#/R-RNO-5685985 EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5685994 https://reactome.org/PathwayBrowser/#/R-RNO-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5686440 https://reactome.org/PathwayBrowser/#/R-RNO-5686440 MUS81:EME1,EME2 cleaves D-loop IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5686642 https://reactome.org/PathwayBrowser/#/R-RNO-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5686657 https://reactome.org/PathwayBrowser/#/R-RNO-5686657 ERCC1:XPF cleaves flaps generated by SSA IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5693539 https://reactome.org/PathwayBrowser/#/R-RNO-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5693542 https://reactome.org/PathwayBrowser/#/R-RNO-5693542 Association of RPA complexes with ssDNA at resected DNA DSBs IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5693564 https://reactome.org/PathwayBrowser/#/R-RNO-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5693580 https://reactome.org/PathwayBrowser/#/R-RNO-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5693584 https://reactome.org/PathwayBrowser/#/R-RNO-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5693593 https://reactome.org/PathwayBrowser/#/R-RNO-5693593 D-loop extension by DNA polymerases IEA Rattus norvegicus A0A0G2K4W8 R-RNO-5693620 https://reactome.org/PathwayBrowser/#/R-RNO-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Rattus norvegicus A0A0G2K4W8 R-RNO-6799332 https://reactome.org/PathwayBrowser/#/R-RNO-6799332 ATR phosphorylates TP53 IEA Rattus norvegicus A0A0G2K4W8 R-RNO-9853389 https://reactome.org/PathwayBrowser/#/R-RNO-9853389 FIGNL1 binds RAD51 IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-2574840 https://reactome.org/PathwayBrowser/#/R-RNO-2574840 AJUBA facilitates AURKA autophosphorylation IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-2574845 https://reactome.org/PathwayBrowser/#/R-RNO-2574845 AJUBA binds centrosome-associated AURKA IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-3000310 https://reactome.org/PathwayBrowser/#/R-RNO-3000310 AURKA phosphorylates PLK1 IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-3000319 https://reactome.org/PathwayBrowser/#/R-RNO-3000319 BORA binds PLK1 and AURKA IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-380272 https://reactome.org/PathwayBrowser/#/R-RNO-380272 Plk1-mediated phosphorylation of Nlp IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-380283 https://reactome.org/PathwayBrowser/#/R-RNO-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-380294 https://reactome.org/PathwayBrowser/#/R-RNO-380294 Loss of C-Nap-1 from centrosomes IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-380303 https://reactome.org/PathwayBrowser/#/R-RNO-380303 Dissociation of Phospho-Nlp from the centrosome IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-380311 https://reactome.org/PathwayBrowser/#/R-RNO-380311 Recruitment of Plk1 to centrosomes IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-380316 https://reactome.org/PathwayBrowser/#/R-RNO-380316 Association of NuMA with microtubules IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-380455 https://reactome.org/PathwayBrowser/#/R-RNO-380455 Recruitment of CDK11p58 to the centrosomes IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-380508 https://reactome.org/PathwayBrowser/#/R-RNO-380508 Translocation of NuMA to the centrosomes IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-5617816 https://reactome.org/PathwayBrowser/#/R-RNO-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-5626220 https://reactome.org/PathwayBrowser/#/R-RNO-5626220 C2CD3 binds the mother centriole IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-5626223 https://reactome.org/PathwayBrowser/#/R-RNO-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-5626227 https://reactome.org/PathwayBrowser/#/R-RNO-5626227 CP110 and CEP97 dissociate from the centriole IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-5626228 https://reactome.org/PathwayBrowser/#/R-RNO-5626228 The distal appendage proteins recruit TTBK2 IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-5626681 https://reactome.org/PathwayBrowser/#/R-RNO-5626681 Recruitment of transition zone proteins IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-5626699 https://reactome.org/PathwayBrowser/#/R-RNO-5626699 MARK4 binds ODF2 in the centriole IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-5638009 https://reactome.org/PathwayBrowser/#/R-RNO-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Rattus norvegicus A0A0G2K4Y6 R-RNO-8853419 https://reactome.org/PathwayBrowser/#/R-RNO-8853419 TPX2 promotes AURKA autophosphorylation IEA Rattus norvegicus A0A0G2K4Z7 R-RNO-168405 https://reactome.org/PathwayBrowser/#/R-RNO-168405 Activated NOD oligomer recruites RIP2 (RICK) IEA Rattus norvegicus A0A0G2K4Z7 R-RNO-168412 https://reactome.org/PathwayBrowser/#/R-RNO-168412 MDP elicits a NOD2 response IEA Rattus norvegicus A0A0G2K4Z7 R-RNO-450337 https://reactome.org/PathwayBrowser/#/R-RNO-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Rattus norvegicus A0A0G2K4Z7 R-RNO-450346 https://reactome.org/PathwayBrowser/#/R-RNO-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Rattus norvegicus A0A0G2K4Z7 R-RNO-622415 https://reactome.org/PathwayBrowser/#/R-RNO-622415 RIP2 binds NEMO IEA Rattus norvegicus A0A0G2K4Z7 R-RNO-688136 https://reactome.org/PathwayBrowser/#/R-RNO-688136 TNFAIP3 (A20) deubiquitinates RIP2 IEA Rattus norvegicus A0A0G2K4Z7 R-RNO-688137 https://reactome.org/PathwayBrowser/#/R-RNO-688137 RIP2 is K63 polyubiquitinated IEA Rattus norvegicus A0A0G2K4Z7 R-RNO-688985 https://reactome.org/PathwayBrowser/#/R-RNO-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex IEA Rattus norvegicus A0A0G2K4Z7 R-RNO-706479 https://reactome.org/PathwayBrowser/#/R-RNO-706479 TAK1 is activated IEA Rattus norvegicus A0A0G2K4Z7 R-RNO-708349 https://reactome.org/PathwayBrowser/#/R-RNO-708349 Activated NOD2 oligomerizes IEA Rattus norvegicus A0A0G2K4Z7 R-RNO-741411 https://reactome.org/PathwayBrowser/#/R-RNO-741411 CYLD deubiquitinates NEMO IEA Rattus norvegicus A0A0G2K4Z7 R-RNO-9676160 https://reactome.org/PathwayBrowser/#/R-RNO-9676160 AAMP binds NOD2 IEA Rattus norvegicus A0A0G2K502 R-RNO-9012268 https://reactome.org/PathwayBrowser/#/R-RNO-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus A0A0G2K502 R-RNO-9838035 https://reactome.org/PathwayBrowser/#/R-RNO-9838035 CLPXP binds mitochondrial matrix proteins IEA Rattus norvegicus A0A0G2K502 R-RNO-9838081 https://reactome.org/PathwayBrowser/#/R-RNO-9838081 LONP1 degrades mitochondrial matrix proteins IEA Rattus norvegicus A0A0G2K502 R-RNO-9838093 https://reactome.org/PathwayBrowser/#/R-RNO-9838093 LONP1 binds mitochondrial matrix proteins IEA Rattus norvegicus A0A0G2K502 R-RNO-9838289 https://reactome.org/PathwayBrowser/#/R-RNO-9838289 CLPXP degrades mitochondrial matrix proteins IEA Rattus norvegicus A0A0G2K505 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus A0A0G2K505 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus A0A0G2K505 R-RNO-419389 https://reactome.org/PathwayBrowser/#/R-RNO-419389 LPA-binding receptors bind LPA IEA Rattus norvegicus A0A0G2K524 R-RNO-110137 https://reactome.org/PathwayBrowser/#/R-RNO-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Rattus norvegicus A0A0G2K524 R-RNO-110138 https://reactome.org/PathwayBrowser/#/R-RNO-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Rattus norvegicus A0A0G2K528 R-RNO-6811431 https://reactome.org/PathwayBrowser/#/R-RNO-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Rattus norvegicus A0A0G2K528 R-RNO-6811433 https://reactome.org/PathwayBrowser/#/R-RNO-6811433 The COG tethering complex interacts with numerous SNAREs at the Golgi membrane IEA Rattus norvegicus A0A0G2K528 R-RNO-6814671 https://reactome.org/PathwayBrowser/#/R-RNO-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Rattus norvegicus A0A0G2K528 R-RNO-6814676 https://reactome.org/PathwayBrowser/#/R-RNO-6814676 SNAPs and NSF hexamer bind cis-SNARE at the TGN IEA Rattus norvegicus A0A0G2K528 R-RNO-6814682 https://reactome.org/PathwayBrowser/#/R-RNO-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Rattus norvegicus A0A0G2K528 R-RNO-6814683 https://reactome.org/PathwayBrowser/#/R-RNO-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN IEA Rattus norvegicus A0A0G2K528 R-RNO-6814684 https://reactome.org/PathwayBrowser/#/R-RNO-6814684 cis-SNARE binds SNAPs and NSF hexamer at the TGN IEA Rattus norvegicus A0A0G2K542 R-RNO-70286 https://reactome.org/PathwayBrowser/#/R-RNO-70286 UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose IEA Rattus norvegicus A0A0G2K548 R-RNO-2574840 https://reactome.org/PathwayBrowser/#/R-RNO-2574840 AJUBA facilitates AURKA autophosphorylation IEA Rattus norvegicus A0A0G2K548 R-RNO-2574845 https://reactome.org/PathwayBrowser/#/R-RNO-2574845 AJUBA binds centrosome-associated AURKA IEA Rattus norvegicus A0A0G2K548 R-RNO-3000310 https://reactome.org/PathwayBrowser/#/R-RNO-3000310 AURKA phosphorylates PLK1 IEA Rattus norvegicus A0A0G2K548 R-RNO-3000319 https://reactome.org/PathwayBrowser/#/R-RNO-3000319 BORA binds PLK1 and AURKA IEA Rattus norvegicus A0A0G2K548 R-RNO-380272 https://reactome.org/PathwayBrowser/#/R-RNO-380272 Plk1-mediated phosphorylation of Nlp IEA Rattus norvegicus A0A0G2K548 R-RNO-380283 https://reactome.org/PathwayBrowser/#/R-RNO-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Rattus norvegicus A0A0G2K548 R-RNO-380294 https://reactome.org/PathwayBrowser/#/R-RNO-380294 Loss of C-Nap-1 from centrosomes IEA Rattus norvegicus A0A0G2K548 R-RNO-380303 https://reactome.org/PathwayBrowser/#/R-RNO-380303 Dissociation of Phospho-Nlp from the centrosome IEA Rattus norvegicus A0A0G2K548 R-RNO-380311 https://reactome.org/PathwayBrowser/#/R-RNO-380311 Recruitment of Plk1 to centrosomes IEA Rattus norvegicus A0A0G2K548 R-RNO-380316 https://reactome.org/PathwayBrowser/#/R-RNO-380316 Association of NuMA with microtubules IEA Rattus norvegicus A0A0G2K548 R-RNO-380455 https://reactome.org/PathwayBrowser/#/R-RNO-380455 Recruitment of CDK11p58 to the centrosomes IEA Rattus norvegicus A0A0G2K548 R-RNO-380508 https://reactome.org/PathwayBrowser/#/R-RNO-380508 Translocation of NuMA to the centrosomes IEA Rattus norvegicus A0A0G2K548 R-RNO-5577050 https://reactome.org/PathwayBrowser/#/R-RNO-5577050 AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region IEA Rattus norvegicus A0A0G2K548 R-RNO-5617816 https://reactome.org/PathwayBrowser/#/R-RNO-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Rattus norvegicus A0A0G2K548 R-RNO-5626220 https://reactome.org/PathwayBrowser/#/R-RNO-5626220 C2CD3 binds the mother centriole IEA Rattus norvegicus A0A0G2K548 R-RNO-5626223 https://reactome.org/PathwayBrowser/#/R-RNO-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Rattus norvegicus A0A0G2K548 R-RNO-5626227 https://reactome.org/PathwayBrowser/#/R-RNO-5626227 CP110 and CEP97 dissociate from the centriole IEA Rattus norvegicus A0A0G2K548 R-RNO-5626228 https://reactome.org/PathwayBrowser/#/R-RNO-5626228 The distal appendage proteins recruit TTBK2 IEA Rattus norvegicus A0A0G2K548 R-RNO-5626681 https://reactome.org/PathwayBrowser/#/R-RNO-5626681 Recruitment of transition zone proteins IEA Rattus norvegicus A0A0G2K548 R-RNO-5626699 https://reactome.org/PathwayBrowser/#/R-RNO-5626699 MARK4 binds ODF2 in the centriole IEA Rattus norvegicus A0A0G2K548 R-RNO-5638009 https://reactome.org/PathwayBrowser/#/R-RNO-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Rattus norvegicus A0A0G2K548 R-RNO-8853419 https://reactome.org/PathwayBrowser/#/R-RNO-8853419 TPX2 promotes AURKA autophosphorylation IEA Rattus norvegicus A0A0G2K557 R-RNO-212252 https://reactome.org/PathwayBrowser/#/R-RNO-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Rattus norvegicus A0A0G2K557 R-RNO-212263 https://reactome.org/PathwayBrowser/#/R-RNO-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Rattus norvegicus A0A0G2K579 R-RNO-162730 https://reactome.org/PathwayBrowser/#/R-RNO-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Rattus norvegicus A0A0G2K5B0 R-RNO-8854173 https://reactome.org/PathwayBrowser/#/R-RNO-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Rattus norvegicus A0A0G2K5C7 R-RNO-9861642 https://reactome.org/PathwayBrowser/#/R-RNO-9861642 NEK1 phosphorylates ME1 IEA Rattus norvegicus A0A0G2K5F6 R-RNO-5685605 https://reactome.org/PathwayBrowser/#/R-RNO-5685605 SLAMF7 binds SLAMF7 IEA Rattus norvegicus A0A0G2K5I7 R-RNO-4722133 https://reactome.org/PathwayBrowser/#/R-RNO-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Rattus norvegicus A0A0G2K5I7 R-RNO-4724279 https://reactome.org/PathwayBrowser/#/R-RNO-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Rattus norvegicus A0A0G2K5I7 R-RNO-5661114 https://reactome.org/PathwayBrowser/#/R-RNO-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Rattus norvegicus A0A0G2K5I7 R-RNO-5661120 https://reactome.org/PathwayBrowser/#/R-RNO-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Rattus norvegicus A0A0G2K5I7 R-RNO-5682586 https://reactome.org/PathwayBrowser/#/R-RNO-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Rattus norvegicus A0A0G2K5I7 R-RNO-5682588 https://reactome.org/PathwayBrowser/#/R-RNO-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Rattus norvegicus A0A0G2K5I7 R-RNO-5682598 https://reactome.org/PathwayBrowser/#/R-RNO-5682598 ATM phosphorylates HERC2 IEA Rattus norvegicus A0A0G2K5I7 R-RNO-5682607 https://reactome.org/PathwayBrowser/#/R-RNO-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Rattus norvegicus A0A0G2K5I7 R-RNO-5682858 https://reactome.org/PathwayBrowser/#/R-RNO-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Rattus norvegicus A0A0G2K5I7 R-RNO-5682863 https://reactome.org/PathwayBrowser/#/R-RNO-5682863 RNF168 binds DNA DSBs IEA Rattus norvegicus A0A0G2K5I7 R-RNO-5682992 https://reactome.org/PathwayBrowser/#/R-RNO-5682992 KDM4A,B bind H4K20Me2 IEA Rattus norvegicus A0A0G2K5I7 R-RNO-5683077 https://reactome.org/PathwayBrowser/#/R-RNO-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Rattus norvegicus A0A0G2K5K4 R-RNO-156526 https://reactome.org/PathwayBrowser/#/R-RNO-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Rattus norvegicus A0A0G2K5K4 R-RNO-211882 https://reactome.org/PathwayBrowser/#/R-RNO-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Rattus norvegicus A0A0G2K5K4 R-RNO-211948 https://reactome.org/PathwayBrowser/#/R-RNO-211948 CYP3A4 can N-demethylate loperamide IEA Rattus norvegicus A0A0G2K5K4 R-RNO-211959 https://reactome.org/PathwayBrowser/#/R-RNO-211959 CYP3A43 6b-hydroxylates TEST IEA Rattus norvegicus A0A0G2K5K4 R-RNO-213175 https://reactome.org/PathwayBrowser/#/R-RNO-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Rattus norvegicus A0A0G2K5K4 R-RNO-5423664 https://reactome.org/PathwayBrowser/#/R-RNO-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Rattus norvegicus A0A0G2K5K4 R-RNO-5423672 https://reactome.org/PathwayBrowser/#/R-RNO-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Rattus norvegicus A0A0G2K5K4 R-RNO-9027043 https://reactome.org/PathwayBrowser/#/R-RNO-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Rattus norvegicus A0A0G2K5K4 R-RNO-9678766 https://reactome.org/PathwayBrowser/#/R-RNO-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Rattus norvegicus A0A0G2K5K4 R-RNO-9680865 https://reactome.org/PathwayBrowser/#/R-RNO-9680865 CYP3A4, CYP2B6 bind ritonavir IEA Rattus norvegicus A0A0G2K5K4 R-RNO-9749986 https://reactome.org/PathwayBrowser/#/R-RNO-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Rattus norvegicus A0A0G2K5K4 R-RNO-9750016 https://reactome.org/PathwayBrowser/#/R-RNO-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Rattus norvegicus A0A0G2K5K4 R-RNO-9756138 https://reactome.org/PathwayBrowser/#/R-RNO-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Rattus norvegicus A0A0G2K5K4 R-RNO-9756162 https://reactome.org/PathwayBrowser/#/R-RNO-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Rattus norvegicus A0A0G2K5K4 R-RNO-9756169 https://reactome.org/PathwayBrowser/#/R-RNO-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Rattus norvegicus A0A0G2K5K4 R-RNO-9756180 https://reactome.org/PathwayBrowser/#/R-RNO-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Rattus norvegicus A0A0G2K5K4 R-RNO-9758674 https://reactome.org/PathwayBrowser/#/R-RNO-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Rattus norvegicus A0A0G2K5L2 R-RNO-8875623 https://reactome.org/PathwayBrowser/#/R-RNO-8875623 SLC25A18,22 import L-Glu, H+ IEA Rattus norvegicus A0A0G2K5L3 R-RNO-6791223 https://reactome.org/PathwayBrowser/#/R-RNO-6791223 18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol IEA Rattus norvegicus A0A0G2K5N0 R-RNO-140978 https://reactome.org/PathwayBrowser/#/R-RNO-140978 TRADD:TRAF2:RIP1 binds FADD IEA Rattus norvegicus A0A0G2K5N0 R-RNO-5357776 https://reactome.org/PathwayBrowser/#/R-RNO-5357776 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG IEA Rattus norvegicus A0A0G2K5N0 R-RNO-5357845 https://reactome.org/PathwayBrowser/#/R-RNO-5357845 K63polyUb-RIPK1 is deubiquitinated IEA Rattus norvegicus A0A0G2K5N0 R-RNO-5357860 https://reactome.org/PathwayBrowser/#/R-RNO-5357860 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex IEA Rattus norvegicus A0A0G2K5N0 R-RNO-5690870 https://reactome.org/PathwayBrowser/#/R-RNO-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Rattus norvegicus A0A0G2K5N0 R-RNO-8869506 https://reactome.org/PathwayBrowser/#/R-RNO-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Rattus norvegicus A0A0G2K5Q6 R-RNO-5624949 https://reactome.org/PathwayBrowser/#/R-RNO-5624949 Assembly of the anterograde IFT train IEA Rattus norvegicus A0A0G2K5Q6 R-RNO-5624952 https://reactome.org/PathwayBrowser/#/R-RNO-5624952 Assembly of the retrograde IFT train IEA Rattus norvegicus A0A0G2K5Q6 R-RNO-5625416 https://reactome.org/PathwayBrowser/#/R-RNO-5625416 Anterograde IFT IEA Rattus norvegicus A0A0G2K5Q6 R-RNO-5625421 https://reactome.org/PathwayBrowser/#/R-RNO-5625421 The anterograde IFT train dissociates IEA Rattus norvegicus A0A0G2K5Q6 R-RNO-5625424 https://reactome.org/PathwayBrowser/#/R-RNO-5625424 The retrograde IFT train dissociates IEA Rattus norvegicus A0A0G2K5Q6 R-RNO-5625426 https://reactome.org/PathwayBrowser/#/R-RNO-5625426 Retrograde IFT IEA Rattus norvegicus A0A0G2K5R3 R-RNO-141409 https://reactome.org/PathwayBrowser/#/R-RNO-141409 Mad1 binds kinetochore IEA Rattus norvegicus A0A0G2K5R3 R-RNO-141422 https://reactome.org/PathwayBrowser/#/R-RNO-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Rattus norvegicus A0A0G2K5R3 R-RNO-141431 https://reactome.org/PathwayBrowser/#/R-RNO-141431 MAD2 associates with the Mad1 kinetochore complex IEA Rattus norvegicus A0A0G2K5R3 R-RNO-141439 https://reactome.org/PathwayBrowser/#/R-RNO-141439 Release of activated MAD2 from kinetochores IEA Rattus norvegicus A0A0G2K5R3 R-RNO-1638803 https://reactome.org/PathwayBrowser/#/R-RNO-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Rattus norvegicus A0A0G2K5R3 R-RNO-1638821 https://reactome.org/PathwayBrowser/#/R-RNO-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Rattus norvegicus A0A0G2K5R3 R-RNO-2467809 https://reactome.org/PathwayBrowser/#/R-RNO-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Rattus norvegicus A0A0G2K5R3 R-RNO-2467811 https://reactome.org/PathwayBrowser/#/R-RNO-2467811 Separation of sister chromatids IEA Rattus norvegicus A0A0G2K5R3 R-RNO-2468287 https://reactome.org/PathwayBrowser/#/R-RNO-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Rattus norvegicus A0A0G2K5R3 R-RNO-2484822 https://reactome.org/PathwayBrowser/#/R-RNO-2484822 Kinetochore assembly IEA Rattus norvegicus A0A0G2K5R3 R-RNO-3000449 https://reactome.org/PathwayBrowser/#/R-RNO-3000449 UBC9 (UBE2I) SUMOylates RANGAP1 with SUMO, which targets RANGAP1 to RANBP2 IEA Rattus norvegicus A0A0G2K5R3 R-RNO-375302 https://reactome.org/PathwayBrowser/#/R-RNO-375302 Kinetochore capture of astral microtubules IEA Rattus norvegicus A0A0G2K5R3 R-RNO-4655355 https://reactome.org/PathwayBrowser/#/R-RNO-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Rattus norvegicus A0A0G2K5R3 R-RNO-5666129 https://reactome.org/PathwayBrowser/#/R-RNO-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Rattus norvegicus A0A0G2K5R3 R-RNO-5666160 https://reactome.org/PathwayBrowser/#/R-RNO-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Rattus norvegicus A0A0G2K5R3 R-RNO-5666169 https://reactome.org/PathwayBrowser/#/R-RNO-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Rattus norvegicus A0A0G2K5R3 R-RNO-9624893 https://reactome.org/PathwayBrowser/#/R-RNO-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Rattus norvegicus A0A0G2K5R3 R-RNO-9648114 https://reactome.org/PathwayBrowser/#/R-RNO-9648114 EML4 recruits NUDC to mitotic spindle IEA Rattus norvegicus A0A0G2K5S0 R-RNO-2534359 https://reactome.org/PathwayBrowser/#/R-RNO-2534359 CatSper Channel Mediated Calcium Transport IEA Rattus norvegicus A0A0G2K5S0 R-RNO-2534388 https://reactome.org/PathwayBrowser/#/R-RNO-2534388 Progesterone Activation Of CatSper IEA Rattus norvegicus A0A0G2K5S7 R-RNO-8851110 https://reactome.org/PathwayBrowser/#/R-RNO-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus A0A0G2K5S7 R-RNO-8851129 https://reactome.org/PathwayBrowser/#/R-RNO-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus A0A0G2K601 R-RNO-1454757 https://reactome.org/PathwayBrowser/#/R-RNO-1454757 Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 IEA Rattus norvegicus A0A0G2K601 R-RNO-1564142 https://reactome.org/PathwayBrowser/#/R-RNO-1564142 Collagen type IV degradation by MMP2,3,4,9,10,12 IEA Rattus norvegicus A0A0G2K601 R-RNO-1650808 https://reactome.org/PathwayBrowser/#/R-RNO-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Rattus norvegicus A0A0G2K601 R-RNO-1980233 https://reactome.org/PathwayBrowser/#/R-RNO-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Rattus norvegicus A0A0G2K601 R-RNO-1981104 https://reactome.org/PathwayBrowser/#/R-RNO-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Rattus norvegicus A0A0G2K601 R-RNO-1981120 https://reactome.org/PathwayBrowser/#/R-RNO-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Rattus norvegicus A0A0G2K601 R-RNO-1981128 https://reactome.org/PathwayBrowser/#/R-RNO-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Rattus norvegicus A0A0G2K601 R-RNO-1981157 https://reactome.org/PathwayBrowser/#/R-RNO-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Rattus norvegicus A0A0G2K601 R-RNO-2002460 https://reactome.org/PathwayBrowser/#/R-RNO-2002460 P4HB binds Collagen chains IEA Rattus norvegicus A0A0G2K601 R-RNO-2089971 https://reactome.org/PathwayBrowser/#/R-RNO-2089971 Secretion of collagens IEA Rattus norvegicus A0A0G2K601 R-RNO-2213207 https://reactome.org/PathwayBrowser/#/R-RNO-2213207 Formation of collagen networks IEA Rattus norvegicus A0A0G2K601 R-RNO-2327695 https://reactome.org/PathwayBrowser/#/R-RNO-2327695 Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 IEA Rattus norvegicus A0A0G2K601 R-RNO-2327733 https://reactome.org/PathwayBrowser/#/R-RNO-2327733 FN1 binds Collagen types I-V, VII IEA Rattus norvegicus A0A0G2K601 R-RNO-2327738 https://reactome.org/PathwayBrowser/#/R-RNO-2327738 DDR1 binds collagen type I, II, III, IV, V, XI fibrils IEA Rattus norvegicus A0A0G2K601 R-RNO-2426450 https://reactome.org/PathwayBrowser/#/R-RNO-2426450 Laminins:Nidogens binds collagen type IV networks IEA Rattus norvegicus A0A0G2K601 R-RNO-2559639 https://reactome.org/PathwayBrowser/#/R-RNO-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Rattus norvegicus A0A0G2K601 R-RNO-8944265 https://reactome.org/PathwayBrowser/#/R-RNO-8944265 Association of procollagen type IV IEA Rattus norvegicus A0A0G2K601 R-RNO-8948219 https://reactome.org/PathwayBrowser/#/R-RNO-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus A0A0G2K601 R-RNO-8948222 https://reactome.org/PathwayBrowser/#/R-RNO-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K601 R-RNO-8948224 https://reactome.org/PathwayBrowser/#/R-RNO-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K601 R-RNO-8948228 https://reactome.org/PathwayBrowser/#/R-RNO-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus A0A0G2K601 R-RNO-8948231 https://reactome.org/PathwayBrowser/#/R-RNO-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K601 R-RNO-8948232 https://reactome.org/PathwayBrowser/#/R-RNO-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Rattus norvegicus A0A0G2K601 R-RNO-8948234 https://reactome.org/PathwayBrowser/#/R-RNO-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K612 R-RNO-201445 https://reactome.org/PathwayBrowser/#/R-RNO-201445 Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8 IEA Rattus norvegicus A0A0G2K612 R-RNO-201821 https://reactome.org/PathwayBrowser/#/R-RNO-201821 I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated IEA Rattus norvegicus A0A0G2K612 R-RNO-2160931 https://reactome.org/PathwayBrowser/#/R-RNO-2160931 Disassembly of tight junctions IEA Rattus norvegicus A0A0G2K612 R-RNO-2160932 https://reactome.org/PathwayBrowser/#/R-RNO-2160932 SMURF1 binds phosphorylated PARD6A IEA Rattus norvegicus A0A0G2K612 R-RNO-2160935 https://reactome.org/PathwayBrowser/#/R-RNO-2160935 SMURF1 ubiquitinates RHOA IEA Rattus norvegicus A0A0G2K612 R-RNO-4608852 https://reactome.org/PathwayBrowser/#/R-RNO-4608852 SMURF1/2 ubiquitinates PRICKLE1 IEA Rattus norvegicus A0A0G2K612 R-RNO-4608854 https://reactome.org/PathwayBrowser/#/R-RNO-4608854 SMURF1/2 are recruited to the DVL2:PARD6A complex IEA Rattus norvegicus A0A0G2K612 R-RNO-5635865 https://reactome.org/PathwayBrowser/#/R-RNO-5635865 SMURF1/2 dissociates from ub-PTCH1 IEA Rattus norvegicus A0A0G2K612 R-RNO-8952419 https://reactome.org/PathwayBrowser/#/R-RNO-8952419 SMURFs ubiquitinate RUNX3 IEA Rattus norvegicus A0A0G2K612 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2K612 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus A0A0G2K612 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2K612 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2K615 R-RNO-606287 https://reactome.org/PathwayBrowser/#/R-RNO-606287 RSF complex binds the centromere IEA Rattus norvegicus A0A0G2K615 R-RNO-606326 https://reactome.org/PathwayBrowser/#/R-RNO-606326 HJURP:CENPA complex localizes to the centromere IEA Rattus norvegicus A0A0G2K615 R-RNO-606349 https://reactome.org/PathwayBrowser/#/R-RNO-606349 Mis18 complex binds the centromere IEA Rattus norvegicus A0A0G2K618 R-RNO-9638090 https://reactome.org/PathwayBrowser/#/R-RNO-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Rattus norvegicus A0A0G2K618 R-RNO-9638097 https://reactome.org/PathwayBrowser/#/R-RNO-9638097 B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA IEA Rattus norvegicus A0A0G2K619 R-RNO-8865774 https://reactome.org/PathwayBrowser/#/R-RNO-8865774 TTLLs polyglutamylate tubulin IEA Rattus norvegicus A0A0G2K626 R-RNO-203973 https://reactome.org/PathwayBrowser/#/R-RNO-203973 Vesicle budding IEA Rattus norvegicus A0A0G2K626 R-RNO-203979 https://reactome.org/PathwayBrowser/#/R-RNO-203979 Coat Assembly IEA Rattus norvegicus A0A0G2K626 R-RNO-204008 https://reactome.org/PathwayBrowser/#/R-RNO-204008 SEC31:SEC13 and v-SNARE recruitment IEA Rattus norvegicus A0A0G2K626 R-RNO-2130731 https://reactome.org/PathwayBrowser/#/R-RNO-2130731 Formation of COPII vesicle IEA Rattus norvegicus A0A0G2K626 R-RNO-2213243 https://reactome.org/PathwayBrowser/#/R-RNO-2213243 Fusion of COPII vesicle with Golgi complex IEA Rattus norvegicus A0A0G2K626 R-RNO-5694409 https://reactome.org/PathwayBrowser/#/R-RNO-5694409 Nucleotide exchange on RAB1 IEA Rattus norvegicus A0A0G2K626 R-RNO-5694413 https://reactome.org/PathwayBrowser/#/R-RNO-5694413 SEC4C,D bind GOSR2 and STX5 IEA Rattus norvegicus A0A0G2K626 R-RNO-5694417 https://reactome.org/PathwayBrowser/#/R-RNO-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Rattus norvegicus A0A0G2K626 R-RNO-5694418 https://reactome.org/PathwayBrowser/#/R-RNO-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Rattus norvegicus A0A0G2K626 R-RNO-5694421 https://reactome.org/PathwayBrowser/#/R-RNO-5694421 PP6 dephosphorylates SEC24 IEA Rattus norvegicus A0A0G2K626 R-RNO-5694435 https://reactome.org/PathwayBrowser/#/R-RNO-5694435 MIA2 and MIA3 load procollagen VII into COPII vesicles IEA Rattus norvegicus A0A0G2K626 R-RNO-5694436 https://reactome.org/PathwayBrowser/#/R-RNO-5694436 MIA2 and MIA3 dissociate from procollagen VII vesicle IEA Rattus norvegicus A0A0G2K626 R-RNO-5694439 https://reactome.org/PathwayBrowser/#/R-RNO-5694439 COPII coat binds TRAPPCII and RAB1:GDP IEA Rattus norvegicus A0A0G2K626 R-RNO-5694441 https://reactome.org/PathwayBrowser/#/R-RNO-5694441 CSNK1D phosphorylates SEC23 IEA Rattus norvegicus A0A0G2K626 R-RNO-5694446 https://reactome.org/PathwayBrowser/#/R-RNO-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Rattus norvegicus A0A0G2K626 R-RNO-5694522 https://reactome.org/PathwayBrowser/#/R-RNO-5694522 Inner coat assembly and cargo binding IEA Rattus norvegicus A0A0G2K626 R-RNO-5694527 https://reactome.org/PathwayBrowser/#/R-RNO-5694527 Loss of SAR1B GTPase IEA Rattus norvegicus A0A0G2K626 R-RNO-983422 https://reactome.org/PathwayBrowser/#/R-RNO-983422 Disassembly of COPII coated vesicle IEA Rattus norvegicus A0A0G2K626 R-RNO-983424 https://reactome.org/PathwayBrowser/#/R-RNO-983424 Budding of COPII coated vesicle IEA Rattus norvegicus A0A0G2K626 R-RNO-983425 https://reactome.org/PathwayBrowser/#/R-RNO-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Rattus norvegicus A0A0G2K628 R-RNO-173481 https://reactome.org/PathwayBrowser/#/R-RNO-173481 SKI/SKIL binds SMAD complex, suppressing TGF-beta signaling IEA Rattus norvegicus A0A0G2K628 R-RNO-201423 https://reactome.org/PathwayBrowser/#/R-RNO-201423 SKI complexes with the Smad complex, suppressing BMP2 signalling IEA Rattus norvegicus A0A0G2K628 R-RNO-2186767 https://reactome.org/PathwayBrowser/#/R-RNO-2186767 Degradation of ubiquitinated SKI/SKIL IEA Rattus norvegicus A0A0G2K652 R-RNO-8956025 https://reactome.org/PathwayBrowser/#/R-RNO-8956025 AcM-UBE2M transfers NEDD8 to CUL9:RBX1 IEA Rattus norvegicus A0A0G2K652 R-RNO-8956026 https://reactome.org/PathwayBrowser/#/R-RNO-8956026 CUL9:RBX1 ubiquitinates BIRC5 IEA Rattus norvegicus A0A0G2K652 R-RNO-8956031 https://reactome.org/PathwayBrowser/#/R-RNO-8956031 NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2K652 R-RNO-8956050 https://reactome.org/PathwayBrowser/#/R-RNO-8956050 NEDD8-CUL9:RBX1 binds CUL7:CCDC8:OBSL1 IEA Rattus norvegicus A0A0G2K654 R-RNO-211239 https://reactome.org/PathwayBrowser/#/R-RNO-211239 Association of DFF40 with chromatin IEA Rattus norvegicus A0A0G2K654 R-RNO-211247 https://reactome.org/PathwayBrowser/#/R-RNO-211247 Cleavage of DNA by DFF40 IEA Rattus norvegicus A0A0G2K664 R-RNO-5624949 https://reactome.org/PathwayBrowser/#/R-RNO-5624949 Assembly of the anterograde IFT train IEA Rattus norvegicus A0A0G2K664 R-RNO-5624952 https://reactome.org/PathwayBrowser/#/R-RNO-5624952 Assembly of the retrograde IFT train IEA Rattus norvegicus A0A0G2K664 R-RNO-5625416 https://reactome.org/PathwayBrowser/#/R-RNO-5625416 Anterograde IFT IEA Rattus norvegicus A0A0G2K664 R-RNO-5625421 https://reactome.org/PathwayBrowser/#/R-RNO-5625421 The anterograde IFT train dissociates IEA Rattus norvegicus A0A0G2K664 R-RNO-5625424 https://reactome.org/PathwayBrowser/#/R-RNO-5625424 The retrograde IFT train dissociates IEA Rattus norvegicus A0A0G2K664 R-RNO-5625426 https://reactome.org/PathwayBrowser/#/R-RNO-5625426 Retrograde IFT IEA Rattus norvegicus A0A0G2K677 R-RNO-392051 https://reactome.org/PathwayBrowser/#/R-RNO-392051 Recruitment of Grb2 to pFAK:NCAM1 IEA Rattus norvegicus A0A0G2K677 R-RNO-392053 https://reactome.org/PathwayBrowser/#/R-RNO-392053 SOS binds Grb2 bound to pFAK:NCAM1 IEA Rattus norvegicus A0A0G2K677 R-RNO-392054 https://reactome.org/PathwayBrowser/#/R-RNO-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Rattus norvegicus A0A0G2K677 R-RNO-392751 https://reactome.org/PathwayBrowser/#/R-RNO-392751 L1 linked to actin cytoskeleton by ankyrin IEA Rattus norvegicus A0A0G2K677 R-RNO-5672965 https://reactome.org/PathwayBrowser/#/R-RNO-5672965 RAS GEFs promote RAS nucleotide exchange IEA Rattus norvegicus A0A0G2K677 R-RNO-6807875 https://reactome.org/PathwayBrowser/#/R-RNO-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Rattus norvegicus A0A0G2K677 R-RNO-6807877 https://reactome.org/PathwayBrowser/#/R-RNO-6807877 ARFGAPs stimulate ARF GTPase activity IEA Rattus norvegicus A0A0G2K677 R-RNO-6809003 https://reactome.org/PathwayBrowser/#/R-RNO-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Rattus norvegicus A0A0G2K677 R-RNO-6809006 https://reactome.org/PathwayBrowser/#/R-RNO-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Rattus norvegicus A0A0G2K677 R-RNO-6809010 https://reactome.org/PathwayBrowser/#/R-RNO-6809010 COPI vesicle uncoating IEA Rattus norvegicus A0A0G2K677 R-RNO-6809011 https://reactome.org/PathwayBrowser/#/R-RNO-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Rattus norvegicus A0A0G2K6D5 R-RNO-8986181 https://reactome.org/PathwayBrowser/#/R-RNO-8986181 PITRM1 proteolyzes mitochondrial targeting peptides (presequences) IEA Rattus norvegicus A0A0G2K6D6 R-RNO-176298 https://reactome.org/PathwayBrowser/#/R-RNO-176298 Activation of claspin IEA Rattus norvegicus A0A0G2K6D6 R-RNO-176318 https://reactome.org/PathwayBrowser/#/R-RNO-176318 Loading of claspin onto DNA during replication origin firing IEA Rattus norvegicus A0A0G2K6D6 R-RNO-68603 https://reactome.org/PathwayBrowser/#/R-RNO-68603 ORC5 binds ORC2:ORC3 IEA Rattus norvegicus A0A0G2K6D6 R-RNO-68610 https://reactome.org/PathwayBrowser/#/R-RNO-68610 Formation of ORC(2-5) complex IEA Rattus norvegicus A0A0G2K6D6 R-RNO-68611 https://reactome.org/PathwayBrowser/#/R-RNO-68611 Formation of ORC(1-5) complex IEA Rattus norvegicus A0A0G2K6D6 R-RNO-68615 https://reactome.org/PathwayBrowser/#/R-RNO-68615 Formation of ORC(1-6) complex IEA Rattus norvegicus A0A0G2K6D6 R-RNO-68688 https://reactome.org/PathwayBrowser/#/R-RNO-68688 CDC6 association with ORC(1-6) at replication origins IEA Rattus norvegicus A0A0G2K6D6 R-RNO-68914 https://reactome.org/PathwayBrowser/#/R-RNO-68914 DNA polymerase alpha:primase binds at the origin IEA Rattus norvegicus A0A0G2K6D6 R-RNO-68916 https://reactome.org/PathwayBrowser/#/R-RNO-68916 DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin IEA Rattus norvegicus A0A0G2K6D6 R-RNO-68918 https://reactome.org/PathwayBrowser/#/R-RNO-68918 CDK and DDK associate with the Mcm10:pre-replicative complex IEA Rattus norvegicus A0A0G2K6D6 R-RNO-68919 https://reactome.org/PathwayBrowser/#/R-RNO-68919 Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 IEA Rattus norvegicus A0A0G2K6D6 R-RNO-68940 https://reactome.org/PathwayBrowser/#/R-RNO-68940 Cdt1 is displaced from the pre-replicative complex IEA Rattus norvegicus A0A0G2K6D6 R-RNO-68944 https://reactome.org/PathwayBrowser/#/R-RNO-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Rattus norvegicus A0A0G2K6D6 R-RNO-68960 https://reactome.org/PathwayBrowser/#/R-RNO-68960 DNA polymerase epsilon binds at the origin IEA Rattus norvegicus A0A0G2K6D8 R-RNO-5688276 https://reactome.org/PathwayBrowser/#/R-RNO-5688276 SIRT4 transfers ADPRib to GLUD IEA Rattus norvegicus A0A0G2K6D8 R-RNO-9861626 https://reactome.org/PathwayBrowser/#/R-RNO-9861626 SIRT4 cleaves lipoyl from DLAT IEA Rattus norvegicus A0A0G2K6E8 R-RNO-448958 https://reactome.org/PathwayBrowser/#/R-RNO-448958 Nuclear translocation of p38 MAPK IEA Rattus norvegicus A0A0G2K6H9 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2K6H9 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus A0A0G2K6H9 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2K6H9 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2K6J1 R-RNO-8877612 https://reactome.org/PathwayBrowser/#/R-RNO-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Rattus norvegicus A0A0G2K6J1 R-RNO-8933446 https://reactome.org/PathwayBrowser/#/R-RNO-8933446 Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling IEA Rattus norvegicus A0A0G2K6J1 R-RNO-8933452 https://reactome.org/PathwayBrowser/#/R-RNO-8933452 YWHAE dimer binds phosphorylated DENND1 proteins IEA Rattus norvegicus A0A0G2K6J4 R-RNO-3257122 https://reactome.org/PathwayBrowser/#/R-RNO-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Rattus norvegicus A0A0G2K6J6 R-RNO-5578712 https://reactome.org/PathwayBrowser/#/R-RNO-5578712 Importin-8 binds AGO2:miRNA IEA Rattus norvegicus A0A0G2K6J6 R-RNO-5578744 https://reactome.org/PathwayBrowser/#/R-RNO-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Rattus norvegicus A0A0G2K6M9 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus A0A0G2K6M9 R-RNO-2197698 https://reactome.org/PathwayBrowser/#/R-RNO-2197698 Src phosphorylate WASP,N-WASP IEA Rattus norvegicus A0A0G2K6M9 R-RNO-2424476 https://reactome.org/PathwayBrowser/#/R-RNO-2424476 Activation of RAC1 by VAV2/3 IEA Rattus norvegicus A0A0G2K6M9 R-RNO-2424481 https://reactome.org/PathwayBrowser/#/R-RNO-2424481 Recruitment of VAV and BTK to p-SLP-76 IEA Rattus norvegicus A0A0G2K6M9 R-RNO-2424484 https://reactome.org/PathwayBrowser/#/R-RNO-2424484 Phosphorylation of BTK by p-SYK IEA Rattus norvegicus A0A0G2K6M9 R-RNO-2424485 https://reactome.org/PathwayBrowser/#/R-RNO-2424485 Release of p-PLCG1 IEA Rattus norvegicus A0A0G2K6M9 R-RNO-2424486 https://reactome.org/PathwayBrowser/#/R-RNO-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Rattus norvegicus A0A0G2K6M9 R-RNO-2424487 https://reactome.org/PathwayBrowser/#/R-RNO-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Rattus norvegicus A0A0G2K6M9 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus A0A0G2K6M9 R-RNO-2730847 https://reactome.org/PathwayBrowser/#/R-RNO-2730847 Hydrolysis of PIP2 by PLCG IEA Rattus norvegicus A0A0G2K6M9 R-RNO-2730858 https://reactome.org/PathwayBrowser/#/R-RNO-2730858 Autophosphorylation of BTK/ITK IEA Rattus norvegicus A0A0G2K6M9 R-RNO-8964246 https://reactome.org/PathwayBrowser/#/R-RNO-8964246 BTK in G alpha (12)-BTK complex is activated IEA Rattus norvegicus A0A0G2K6M9 R-RNO-8964274 https://reactome.org/PathwayBrowser/#/R-RNO-8964274 G alpha (12) binds BTK IEA Rattus norvegicus A0A0G2K6M9 R-RNO-8964280 https://reactome.org/PathwayBrowser/#/R-RNO-8964280 Active Gq binds BTK IEA Rattus norvegicus A0A0G2K6M9 R-RNO-8964284 https://reactome.org/PathwayBrowser/#/R-RNO-8964284 BTK in active Gq-BTK complex is activated IEA Rattus norvegicus A0A0G2K6M9 R-RNO-8964333 https://reactome.org/PathwayBrowser/#/R-RNO-8964333 G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) IEA Rattus norvegicus A0A0G2K6M9 R-RNO-8964340 https://reactome.org/PathwayBrowser/#/R-RNO-8964340 Gq-BTK complex dissociates to Active BTK and Gq IEA Rattus norvegicus A0A0G2K6M9 R-RNO-9606151 https://reactome.org/PathwayBrowser/#/R-RNO-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Rattus norvegicus A0A0G2K6M9 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus A0A0G2K6P4 R-RNO-168166 https://reactome.org/PathwayBrowser/#/R-RNO-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Rattus norvegicus A0A0G2K6P4 R-RNO-211247 https://reactome.org/PathwayBrowser/#/R-RNO-211247 Cleavage of DNA by DFF40 IEA Rattus norvegicus A0A0G2K6P4 R-RNO-266204 https://reactome.org/PathwayBrowser/#/R-RNO-266204 Association of HMGB1/HMGB2 with chromatin IEA Rattus norvegicus A0A0G2K6P4 R-RNO-5432825 https://reactome.org/PathwayBrowser/#/R-RNO-5432825 HMGB1 binds TLR4:LY96 IEA Rattus norvegicus A0A0G2K6P4 R-RNO-6798748 https://reactome.org/PathwayBrowser/#/R-RNO-6798748 Exocytosis of secretory granule lumen proteins IEA Rattus norvegicus A0A0G2K6P4 R-RNO-6800434 https://reactome.org/PathwayBrowser/#/R-RNO-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Rattus norvegicus A0A0G2K6P4 R-RNO-6804099 https://reactome.org/PathwayBrowser/#/R-RNO-6804099 HMGB1 binds LTP IEA Rattus norvegicus A0A0G2K6P4 R-RNO-6804100 https://reactome.org/PathwayBrowser/#/R-RNO-6804100 HMGB1 binds LPS IEA Rattus norvegicus A0A0G2K6P4 R-RNO-6805981 https://reactome.org/PathwayBrowser/#/R-RNO-6805981 HMGB1 release from cells IEA Rattus norvegicus A0A0G2K6P4 R-RNO-879411 https://reactome.org/PathwayBrowser/#/R-RNO-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Rattus norvegicus A0A0G2K6Q8 R-RNO-3247837 https://reactome.org/PathwayBrowser/#/R-RNO-3247837 WNT ligands traffic to the Golgi IEA Rattus norvegicus A0A0G2K6Q8 R-RNO-3247840 https://reactome.org/PathwayBrowser/#/R-RNO-3247840 WLS binds WNT ligands in the Golgi IEA Rattus norvegicus A0A0G2K6Q8 R-RNO-3247843 https://reactome.org/PathwayBrowser/#/R-RNO-3247843 secretion of WNT ligands IEA Rattus norvegicus A0A0G2K6Q8 R-RNO-3247844 https://reactome.org/PathwayBrowser/#/R-RNO-3247844 WNT ligands traffic to the plasma membrane IEA Rattus norvegicus A0A0G2K6Q8 R-RNO-3781941 https://reactome.org/PathwayBrowser/#/R-RNO-3781941 WNTs are secreted in exosomes IEA Rattus norvegicus A0A0G2K6Q8 R-RNO-3781943 https://reactome.org/PathwayBrowser/#/R-RNO-3781943 WLS:WNT complex is internalized for maturation into exosomes IEA Rattus norvegicus A0A0G2K6R0 R-RNO-426489 https://reactome.org/PathwayBrowser/#/R-RNO-426489 RISC binds inexactly matching target RNAs IEA Rattus norvegicus A0A0G2K6R0 R-RNO-426522 https://reactome.org/PathwayBrowser/#/R-RNO-426522 Nonendonucleolytic RISC binds exactly matching target RNAs IEA Rattus norvegicus A0A0G2K6T6 R-RNO-5159245 https://reactome.org/PathwayBrowser/#/R-RNO-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Rattus norvegicus A0A0G2K6T6 R-RNO-5244692 https://reactome.org/PathwayBrowser/#/R-RNO-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Rattus norvegicus A0A0G2K6T6 R-RNO-5637686 https://reactome.org/PathwayBrowser/#/R-RNO-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Rattus norvegicus A0A0G2K6T6 R-RNO-8936481 https://reactome.org/PathwayBrowser/#/R-RNO-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Rattus norvegicus A0A0G2K6T6 R-RNO-8936621 https://reactome.org/PathwayBrowser/#/R-RNO-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Rattus norvegicus A0A0G2K6T6 R-RNO-8937016 https://reactome.org/PathwayBrowser/#/R-RNO-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Rattus norvegicus A0A0G2K6T6 R-RNO-8937050 https://reactome.org/PathwayBrowser/#/R-RNO-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Rattus norvegicus A0A0G2K6T6 R-RNO-9676257 https://reactome.org/PathwayBrowser/#/R-RNO-9676257 Formation of the SET1A complex IEA Rattus norvegicus A0A0G2K6T6 R-RNO-9821475 https://reactome.org/PathwayBrowser/#/R-RNO-9821475 CXXC1 and WDR82 bind SET1A complex IEA Rattus norvegicus A0A0G2K6T6 R-RNO-9821486 https://reactome.org/PathwayBrowser/#/R-RNO-9821486 HCFC1 binds SET1A complex IEA Rattus norvegicus A0A0G2K6T6 R-RNO-9821931 https://reactome.org/PathwayBrowser/#/R-RNO-9821931 BOD1L1 binds SET1A complex IEA Rattus norvegicus A0A0G2K6V2 R-RNO-4754181 https://reactome.org/PathwayBrowser/#/R-RNO-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Rattus norvegicus A0A0G2K6V2 R-RNO-5661116 https://reactome.org/PathwayBrowser/#/R-RNO-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Rattus norvegicus A0A0G2K735 R-RNO-1169397 https://reactome.org/PathwayBrowser/#/R-RNO-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Rattus norvegicus A0A0G2K735 R-RNO-1169404 https://reactome.org/PathwayBrowser/#/R-RNO-1169404 Transfer of ISG15 from E1 to E2 (UBCH8) IEA Rattus norvegicus A0A0G2K735 R-RNO-5653754 https://reactome.org/PathwayBrowser/#/R-RNO-5653754 UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA IEA Rattus norvegicus A0A0G2K735 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2K735 R-RNO-983152 https://reactome.org/PathwayBrowser/#/R-RNO-983152 Transfer of ubiquitin from E1 to E2 IEA Rattus norvegicus A0A0G2K735 R-RNO-983153 https://reactome.org/PathwayBrowser/#/R-RNO-983153 E1 mediated ubiquitin activation IEA Rattus norvegicus A0A0G2K735 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2K735 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2K735 R-RNO-9927247 https://reactome.org/PathwayBrowser/#/R-RNO-9927247 ISGylation of DDX58 (RIG-I) IEA Rattus norvegicus A0A0G2K736 R-RNO-3214912 https://reactome.org/PathwayBrowser/#/R-RNO-3214912 KDM1A, KDM1B demethylate MeK5-histone H3 IEA Rattus norvegicus A0A0G2K736 R-RNO-5625848 https://reactome.org/PathwayBrowser/#/R-RNO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus A0A0G2K736 R-RNO-5625849 https://reactome.org/PathwayBrowser/#/R-RNO-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Rattus norvegicus A0A0G2K736 R-RNO-5625870 https://reactome.org/PathwayBrowser/#/R-RNO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus A0A0G2K736 R-RNO-5661123 https://reactome.org/PathwayBrowser/#/R-RNO-5661123 KDM1A, KDM1B demethylate Me2K5-histone H3 IEA Rattus norvegicus A0A0G2K736 R-RNO-9011984 https://reactome.org/PathwayBrowser/#/R-RNO-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Rattus norvegicus A0A0G2K736 R-RNO-9011985 https://reactome.org/PathwayBrowser/#/R-RNO-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Rattus norvegicus A0A0G2K736 R-RNO-9679787 https://reactome.org/PathwayBrowser/#/R-RNO-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Rattus norvegicus A0A0G2K736 R-RNO-996727 https://reactome.org/PathwayBrowser/#/R-RNO-996727 REST recruits the BHC complex IEA Rattus norvegicus A0A0G2K742 R-RNO-1454757 https://reactome.org/PathwayBrowser/#/R-RNO-1454757 Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 IEA Rattus norvegicus A0A0G2K742 R-RNO-1564142 https://reactome.org/PathwayBrowser/#/R-RNO-1564142 Collagen type IV degradation by MMP2,3,4,9,10,12 IEA Rattus norvegicus A0A0G2K742 R-RNO-1650808 https://reactome.org/PathwayBrowser/#/R-RNO-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Rattus norvegicus A0A0G2K742 R-RNO-1980233 https://reactome.org/PathwayBrowser/#/R-RNO-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Rattus norvegicus A0A0G2K742 R-RNO-1981104 https://reactome.org/PathwayBrowser/#/R-RNO-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Rattus norvegicus A0A0G2K742 R-RNO-1981120 https://reactome.org/PathwayBrowser/#/R-RNO-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Rattus norvegicus A0A0G2K742 R-RNO-1981128 https://reactome.org/PathwayBrowser/#/R-RNO-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Rattus norvegicus A0A0G2K742 R-RNO-1981157 https://reactome.org/PathwayBrowser/#/R-RNO-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Rattus norvegicus A0A0G2K742 R-RNO-2002460 https://reactome.org/PathwayBrowser/#/R-RNO-2002460 P4HB binds Collagen chains IEA Rattus norvegicus A0A0G2K742 R-RNO-2089971 https://reactome.org/PathwayBrowser/#/R-RNO-2089971 Secretion of collagens IEA Rattus norvegicus A0A0G2K742 R-RNO-2213207 https://reactome.org/PathwayBrowser/#/R-RNO-2213207 Formation of collagen networks IEA Rattus norvegicus A0A0G2K742 R-RNO-2327695 https://reactome.org/PathwayBrowser/#/R-RNO-2327695 Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 IEA Rattus norvegicus A0A0G2K742 R-RNO-2327733 https://reactome.org/PathwayBrowser/#/R-RNO-2327733 FN1 binds Collagen types I-V, VII IEA Rattus norvegicus A0A0G2K742 R-RNO-2327738 https://reactome.org/PathwayBrowser/#/R-RNO-2327738 DDR1 binds collagen type I, II, III, IV, V, XI fibrils IEA Rattus norvegicus A0A0G2K742 R-RNO-2426450 https://reactome.org/PathwayBrowser/#/R-RNO-2426450 Laminins:Nidogens binds collagen type IV networks IEA Rattus norvegicus A0A0G2K742 R-RNO-2559639 https://reactome.org/PathwayBrowser/#/R-RNO-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Rattus norvegicus A0A0G2K742 R-RNO-375151 https://reactome.org/PathwayBrowser/#/R-RNO-375151 Interaction of NCAM1 with collagens IEA Rattus norvegicus A0A0G2K742 R-RNO-382054 https://reactome.org/PathwayBrowser/#/R-RNO-382054 PDGF binds to extracellular matrix proteins IEA Rattus norvegicus A0A0G2K742 R-RNO-4088218 https://reactome.org/PathwayBrowser/#/R-RNO-4088218 Tetrastatin binds integrin alphaVbeta3 IEA Rattus norvegicus A0A0G2K742 R-RNO-8944265 https://reactome.org/PathwayBrowser/#/R-RNO-8944265 Association of procollagen type IV IEA Rattus norvegicus A0A0G2K742 R-RNO-8948219 https://reactome.org/PathwayBrowser/#/R-RNO-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus A0A0G2K742 R-RNO-8948222 https://reactome.org/PathwayBrowser/#/R-RNO-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K742 R-RNO-8948224 https://reactome.org/PathwayBrowser/#/R-RNO-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K742 R-RNO-8948228 https://reactome.org/PathwayBrowser/#/R-RNO-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus A0A0G2K742 R-RNO-8948231 https://reactome.org/PathwayBrowser/#/R-RNO-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K742 R-RNO-8948232 https://reactome.org/PathwayBrowser/#/R-RNO-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Rattus norvegicus A0A0G2K742 R-RNO-8948234 https://reactome.org/PathwayBrowser/#/R-RNO-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K7A5 R-RNO-1454757 https://reactome.org/PathwayBrowser/#/R-RNO-1454757 Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 IEA Rattus norvegicus A0A0G2K7A5 R-RNO-1650808 https://reactome.org/PathwayBrowser/#/R-RNO-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Rattus norvegicus A0A0G2K7A5 R-RNO-1980233 https://reactome.org/PathwayBrowser/#/R-RNO-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Rattus norvegicus A0A0G2K7A5 R-RNO-1981104 https://reactome.org/PathwayBrowser/#/R-RNO-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Rattus norvegicus A0A0G2K7A5 R-RNO-1981120 https://reactome.org/PathwayBrowser/#/R-RNO-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Rattus norvegicus A0A0G2K7A5 R-RNO-1981128 https://reactome.org/PathwayBrowser/#/R-RNO-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Rattus norvegicus A0A0G2K7A5 R-RNO-1981157 https://reactome.org/PathwayBrowser/#/R-RNO-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Rattus norvegicus A0A0G2K7A5 R-RNO-2002460 https://reactome.org/PathwayBrowser/#/R-RNO-2002460 P4HB binds Collagen chains IEA Rattus norvegicus A0A0G2K7A5 R-RNO-2089971 https://reactome.org/PathwayBrowser/#/R-RNO-2089971 Secretion of collagens IEA Rattus norvegicus A0A0G2K7A5 R-RNO-2213207 https://reactome.org/PathwayBrowser/#/R-RNO-2213207 Formation of collagen networks IEA Rattus norvegicus A0A0G2K7A5 R-RNO-2213208 https://reactome.org/PathwayBrowser/#/R-RNO-2213208 Type X collagen associates with collagen type II fibrils IEA Rattus norvegicus A0A0G2K7A5 R-RNO-2465890 https://reactome.org/PathwayBrowser/#/R-RNO-2465890 DDR2 binds collagen type I, II, III, V, X fibrils IEA Rattus norvegicus A0A0G2K7A5 R-RNO-8944262 https://reactome.org/PathwayBrowser/#/R-RNO-8944262 Association of procollagen type X IEA Rattus norvegicus A0A0G2K7A5 R-RNO-8948219 https://reactome.org/PathwayBrowser/#/R-RNO-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus A0A0G2K7A5 R-RNO-8948222 https://reactome.org/PathwayBrowser/#/R-RNO-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K7A5 R-RNO-8948224 https://reactome.org/PathwayBrowser/#/R-RNO-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K7A5 R-RNO-8948228 https://reactome.org/PathwayBrowser/#/R-RNO-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus A0A0G2K7A5 R-RNO-8948231 https://reactome.org/PathwayBrowser/#/R-RNO-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K7A5 R-RNO-8948232 https://reactome.org/PathwayBrowser/#/R-RNO-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Rattus norvegicus A0A0G2K7A5 R-RNO-8948234 https://reactome.org/PathwayBrowser/#/R-RNO-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K7F0 R-RNO-6785342 https://reactome.org/PathwayBrowser/#/R-RNO-6785342 FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex IEA Rattus norvegicus A0A0G2K7F0 R-RNO-6785361 https://reactome.org/PathwayBrowser/#/R-RNO-6785361 Monoubiquitination of FANCD2:FANCI IEA Rattus norvegicus A0A0G2K7F0 R-RNO-6785607 https://reactome.org/PathwayBrowser/#/R-RNO-6785607 FANCM binds FAAP24 IEA Rattus norvegicus A0A0G2K7F0 R-RNO-6785732 https://reactome.org/PathwayBrowser/#/R-RNO-6785732 DNA nucleases bind monoubiquitinated ID2 complex IEA Rattus norvegicus A0A0G2K7F0 R-RNO-6785986 https://reactome.org/PathwayBrowser/#/R-RNO-6785986 DNA nucleases unhook the interstrand crosslink (ICL) IEA Rattus norvegicus A0A0G2K7F0 R-RNO-6786155 https://reactome.org/PathwayBrowser/#/R-RNO-6786155 POLN binds ICL-DNA IEA Rattus norvegicus A0A0G2K7F0 R-RNO-6786166 https://reactome.org/PathwayBrowser/#/R-RNO-6786166 Translesion synthesis across unhooked ICL by POLN IEA Rattus norvegicus A0A0G2K7F0 R-RNO-6786171 https://reactome.org/PathwayBrowser/#/R-RNO-6786171 FANCD2 deubiquitination by USP1:WDR48 IEA Rattus norvegicus A0A0G2K7F0 R-RNO-6788385 https://reactome.org/PathwayBrowser/#/R-RNO-6788385 The complex of ATR and ATRIP is recruited to ICL-DNA IEA Rattus norvegicus A0A0G2K7F0 R-RNO-6788392 https://reactome.org/PathwayBrowser/#/R-RNO-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Rattus norvegicus A0A0G2K7F0 R-RNO-9835411 https://reactome.org/PathwayBrowser/#/R-RNO-9835411 FA core complex:HSP70s binds PKR IEA Rattus norvegicus A0A0G2K7F8 R-RNO-2168889 https://reactome.org/PathwayBrowser/#/R-RNO-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Rattus norvegicus A0A0G2K7F8 R-RNO-8952289 https://reactome.org/PathwayBrowser/#/R-RNO-8952289 FAM20C phosphorylates FAM20C substrates IEA Rattus norvegicus A0A0G2K7L4 R-RNO-1855159 https://reactome.org/PathwayBrowser/#/R-RNO-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Rattus norvegicus A0A0G2K7L4 R-RNO-1855162 https://reactome.org/PathwayBrowser/#/R-RNO-1855162 I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol IEA Rattus norvegicus A0A0G2K7L4 R-RNO-1855169 https://reactome.org/PathwayBrowser/#/R-RNO-1855169 I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus A0A0G2K7L4 R-RNO-1855171 https://reactome.org/PathwayBrowser/#/R-RNO-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Rattus norvegicus A0A0G2K7L4 R-RNO-1855172 https://reactome.org/PathwayBrowser/#/R-RNO-1855172 I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol IEA Rattus norvegicus A0A0G2K7L4 R-RNO-1855197 https://reactome.org/PathwayBrowser/#/R-RNO-1855197 I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus A0A0G2K7L4 R-RNO-1855218 https://reactome.org/PathwayBrowser/#/R-RNO-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Rattus norvegicus A0A0G2K7L4 R-RNO-1855219 https://reactome.org/PathwayBrowser/#/R-RNO-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus A0A0G2K7L4 R-RNO-2267372 https://reactome.org/PathwayBrowser/#/R-RNO-2267372 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 IEA Rattus norvegicus A0A0G2K7L4 R-RNO-994137 https://reactome.org/PathwayBrowser/#/R-RNO-994137 ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 IEA Rattus norvegicus A0A0G2K7L4 R-RNO-994140 https://reactome.org/PathwayBrowser/#/R-RNO-994140 ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 IEA Rattus norvegicus A0A0G2K7M4 R-RNO-8854408 https://reactome.org/PathwayBrowser/#/R-RNO-8854408 APOBR dimer binds VLDLs IEA Rattus norvegicus A0A0G2K7N9 R-RNO-8981637 https://reactome.org/PathwayBrowser/#/R-RNO-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Rattus norvegicus A0A0G2K7N9 R-RNO-9013022 https://reactome.org/PathwayBrowser/#/R-RNO-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Rattus norvegicus A0A0G2K7N9 R-RNO-9013144 https://reactome.org/PathwayBrowser/#/R-RNO-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Rattus norvegicus A0A0G2K7N9 R-RNO-9013161 https://reactome.org/PathwayBrowser/#/R-RNO-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Rattus norvegicus A0A0G2K7N9 R-RNO-9013437 https://reactome.org/PathwayBrowser/#/R-RNO-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Rattus norvegicus A0A0G2K7N9 R-RNO-9014434 https://reactome.org/PathwayBrowser/#/R-RNO-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Rattus norvegicus A0A0G2K7N9 R-RNO-9017488 https://reactome.org/PathwayBrowser/#/R-RNO-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Rattus norvegicus A0A0G2K7N9 R-RNO-9018745 https://reactome.org/PathwayBrowser/#/R-RNO-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Rattus norvegicus A0A0G2K7N9 R-RNO-9693282 https://reactome.org/PathwayBrowser/#/R-RNO-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Rattus norvegicus A0A0G2K7N9 R-RNO-9696266 https://reactome.org/PathwayBrowser/#/R-RNO-9696266 RND2 binds effectors IEA Rattus norvegicus A0A0G2K7N9 R-RNO-9696268 https://reactome.org/PathwayBrowser/#/R-RNO-9696268 RND3 binds effectors IEA Rattus norvegicus A0A0G2K7N9 R-RNO-9696271 https://reactome.org/PathwayBrowser/#/R-RNO-9696271 RND1 binds effectors IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8865454 https://reactome.org/PathwayBrowser/#/R-RNO-8865454 CBFB binds RUNX3 IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8878117 https://reactome.org/PathwayBrowser/#/R-RNO-8878117 RUNX3 binds ZFHX3 IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8878143 https://reactome.org/PathwayBrowser/#/R-RNO-8878143 RUNX3 binds SMAD3 and SMAD4 IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8878220 https://reactome.org/PathwayBrowser/#/R-RNO-8878220 RUNX3 binds the NOTCH1 coactivator complex IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8937792 https://reactome.org/PathwayBrowser/#/R-RNO-8937792 RUNX3 binds SRC IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8937807 https://reactome.org/PathwayBrowser/#/R-RNO-8937807 SRC phosphorylates RUNX3 IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8937814 https://reactome.org/PathwayBrowser/#/R-RNO-8937814 RUNX3 translocates to the nucleus IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8951428 https://reactome.org/PathwayBrowser/#/R-RNO-8951428 RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8951676 https://reactome.org/PathwayBrowser/#/R-RNO-8951676 RUNX3 binds TEADs and YAP1 IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8951951 https://reactome.org/PathwayBrowser/#/R-RNO-8951951 RUNX3 binds EP300 IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8951966 https://reactome.org/PathwayBrowser/#/R-RNO-8951966 EP300 acetylates RUNX3 IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8952058 https://reactome.org/PathwayBrowser/#/R-RNO-8952058 CCND1 binds RUNX3 and displaces EP300 IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8952062 https://reactome.org/PathwayBrowser/#/R-RNO-8952062 CCND1 recruits HDAC4 to RUNX3 IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8952128 https://reactome.org/PathwayBrowser/#/R-RNO-8952128 RUNX3 binds TP53 IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8952371 https://reactome.org/PathwayBrowser/#/R-RNO-8952371 MDM2 binds RUNX3 IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8952382 https://reactome.org/PathwayBrowser/#/R-RNO-8952382 MDM2 polyubiquitinates RUNX3 IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8952399 https://reactome.org/PathwayBrowser/#/R-RNO-8952399 Polyubiquitinated RUNX3 translocates to the cytosol IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8952408 https://reactome.org/PathwayBrowser/#/R-RNO-8952408 Polyubiquitinated RUNX3 is degraded by the proteasome IEA Rattus norvegicus A0A0G2K7T0 R-RNO-8952419 https://reactome.org/PathwayBrowser/#/R-RNO-8952419 SMURFs ubiquitinate RUNX3 IEA Rattus norvegicus A0A0G2K7U7 R-RNO-8876837 https://reactome.org/PathwayBrowser/#/R-RNO-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Rattus norvegicus A0A0G2K7X2 R-RNO-166245 https://reactome.org/PathwayBrowser/#/R-RNO-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Rattus norvegicus A0A0G2K7X2 R-RNO-166271 https://reactome.org/PathwayBrowser/#/R-RNO-166271 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 IEA Rattus norvegicus A0A0G2K7X2 R-RNO-2201338 https://reactome.org/PathwayBrowser/#/R-RNO-2201338 TRAF3 binds TICAM1:activated TLR4 complex IEA Rattus norvegicus A0A0G2K7X2 R-RNO-2213017 https://reactome.org/PathwayBrowser/#/R-RNO-2213017 Auto-ubiquitination of TRAF3 IEA Rattus norvegicus A0A0G2K7X2 R-RNO-5362486 https://reactome.org/PathwayBrowser/#/R-RNO-5362486 TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4 IEA Rattus norvegicus A0A0G2K7X2 R-RNO-5362500 https://reactome.org/PathwayBrowser/#/R-RNO-5362500 TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Rattus norvegicus A0A0G2K7X2 R-RNO-5668414 https://reactome.org/PathwayBrowser/#/R-RNO-5668414 TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK IEA Rattus norvegicus A0A0G2K7X2 R-RNO-5668417 https://reactome.org/PathwayBrowser/#/R-RNO-5668417 cIAP1,2:TRAF2:TRAF3:NIK complex binds TNFR2 trimer IEA Rattus norvegicus A0A0G2K7X2 R-RNO-5668454 https://reactome.org/PathwayBrowser/#/R-RNO-5668454 K63polyUb-cIAP1,2 ubiquitinates TRAF3 IEA Rattus norvegicus A0A0G2K7X2 R-RNO-5668481 https://reactome.org/PathwayBrowser/#/R-RNO-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Rattus norvegicus A0A0G2K7X2 R-RNO-5668534 https://reactome.org/PathwayBrowser/#/R-RNO-5668534 cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK IEA Rattus norvegicus A0A0G2K7X2 R-RNO-5668543 https://reactome.org/PathwayBrowser/#/R-RNO-5668543 TRAF3:NIK binds TRAF2:cIAP1/2 IEA Rattus norvegicus A0A0G2K7X2 R-RNO-5676593 https://reactome.org/PathwayBrowser/#/R-RNO-5676593 TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR IEA Rattus norvegicus A0A0G2K7X2 R-RNO-5676595 https://reactome.org/PathwayBrowser/#/R-RNO-5676595 TRAFs bind RANK:RANKL IEA Rattus norvegicus A0A0G2K7X2 R-RNO-5676596 https://reactome.org/PathwayBrowser/#/R-RNO-5676596 TRAF3 binds BAFFR:BAFF IEA Rattus norvegicus A0A0G2K7X2 R-RNO-5676597 https://reactome.org/PathwayBrowser/#/R-RNO-5676597 TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 IEA Rattus norvegicus A0A0G2K7X2 R-RNO-5676598 https://reactome.org/PathwayBrowser/#/R-RNO-5676598 TRAF2:cIAP1/2 complex binds FN14:TWEAK IEA Rattus norvegicus A0A0G2K7X2 R-RNO-5690843 https://reactome.org/PathwayBrowser/#/R-RNO-5690843 OTUB1, (OTUB2) binds RNF128, TRAF3, TRAF6, RHOA IEA Rattus norvegicus A0A0G2K7X2 R-RNO-9823904 https://reactome.org/PathwayBrowser/#/R-RNO-9823904 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Rattus norvegicus A0A0G2K7X2 R-RNO-9823906 https://reactome.org/PathwayBrowser/#/R-RNO-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Rattus norvegicus A0A0G2K7X2 R-RNO-9823910 https://reactome.org/PathwayBrowser/#/R-RNO-9823910 Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Rattus norvegicus A0A0G2K7X2 R-RNO-9823932 https://reactome.org/PathwayBrowser/#/R-RNO-9823932 Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Rattus norvegicus A0A0G2K7X2 R-RNO-9823934 https://reactome.org/PathwayBrowser/#/R-RNO-9823934 OPTN binds TBK1 within the activated TLR4 complex IEA Rattus norvegicus A0A0G2K7X2 R-RNO-9823939 https://reactome.org/PathwayBrowser/#/R-RNO-9823939 IKKε (IKBKE) is ubiquitinated within the activated TLR4 IEA Rattus norvegicus A0A0G2K7X2 R-RNO-9824882 https://reactome.org/PathwayBrowser/#/R-RNO-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Rattus norvegicus A0A0G2K7Z7 R-RNO-6800334 https://reactome.org/PathwayBrowser/#/R-RNO-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Rattus norvegicus A0A0G2K828 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus A0A0G2K828 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus A0A0G2K828 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus A0A0G2K828 R-RNO-173626 https://reactome.org/PathwayBrowser/#/R-RNO-173626 Activation of C1r IEA Rattus norvegicus A0A0G2K828 R-RNO-173631 https://reactome.org/PathwayBrowser/#/R-RNO-173631 Activation of C1s IEA Rattus norvegicus A0A0G2K828 R-RNO-1861621 https://reactome.org/PathwayBrowser/#/R-RNO-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K828 R-RNO-199161 https://reactome.org/PathwayBrowser/#/R-RNO-199161 Fc gamma receptors interact with antigen-bound IgG IEA Rattus norvegicus A0A0G2K828 R-RNO-2029268 https://reactome.org/PathwayBrowser/#/R-RNO-2029268 Phosphorylation and activation of PLCG IEA Rattus norvegicus A0A0G2K828 R-RNO-2029270 https://reactome.org/PathwayBrowser/#/R-RNO-2029270 Recruitment of PLCgamma to membrane IEA Rattus norvegicus A0A0G2K828 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K828 R-RNO-2029272 https://reactome.org/PathwayBrowser/#/R-RNO-2029272 Release of PLCG from FCGR IEA Rattus norvegicus A0A0G2K828 R-RNO-2029273 https://reactome.org/PathwayBrowser/#/R-RNO-2029273 PI3K binds to p-6Y-SYK IEA Rattus norvegicus A0A0G2K828 R-RNO-2029451 https://reactome.org/PathwayBrowser/#/R-RNO-2029451 Activation of RAC1 by VAV IEA Rattus norvegicus A0A0G2K828 R-RNO-2029452 https://reactome.org/PathwayBrowser/#/R-RNO-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Rattus norvegicus A0A0G2K828 R-RNO-2029453 https://reactome.org/PathwayBrowser/#/R-RNO-2029453 Phosphorylation of VAV IEA Rattus norvegicus A0A0G2K828 R-RNO-2029455 https://reactome.org/PathwayBrowser/#/R-RNO-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K828 R-RNO-2029457 https://reactome.org/PathwayBrowser/#/R-RNO-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K828 R-RNO-2029458 https://reactome.org/PathwayBrowser/#/R-RNO-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Rattus norvegicus A0A0G2K828 R-RNO-2029459 https://reactome.org/PathwayBrowser/#/R-RNO-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Rattus norvegicus A0A0G2K828 R-RNO-2029467 https://reactome.org/PathwayBrowser/#/R-RNO-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Rattus norvegicus A0A0G2K828 R-RNO-2029476 https://reactome.org/PathwayBrowser/#/R-RNO-2029476 Role of myosins in phagosome formation IEA Rattus norvegicus A0A0G2K828 R-RNO-2203516 https://reactome.org/PathwayBrowser/#/R-RNO-2203516 Alpha-1-Microglobulin is cleaved IEA Rattus norvegicus A0A0G2K828 R-RNO-2454192 https://reactome.org/PathwayBrowser/#/R-RNO-2454192 Allergen dependent IgE bound FCERI aggregation IEA Rattus norvegicus A0A0G2K828 R-RNO-2454208 https://reactome.org/PathwayBrowser/#/R-RNO-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Rattus norvegicus A0A0G2K828 R-RNO-2454240 https://reactome.org/PathwayBrowser/#/R-RNO-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Rattus norvegicus A0A0G2K828 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus A0A0G2K828 R-RNO-2730843 https://reactome.org/PathwayBrowser/#/R-RNO-2730843 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus A0A0G2K828 R-RNO-2730851 https://reactome.org/PathwayBrowser/#/R-RNO-2730851 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus A0A0G2K828 R-RNO-2730882 https://reactome.org/PathwayBrowser/#/R-RNO-2730882 Phosphorylation of PKC-theta IEA Rattus norvegicus A0A0G2K828 R-RNO-2730884 https://reactome.org/PathwayBrowser/#/R-RNO-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Rattus norvegicus A0A0G2K828 R-RNO-2730886 https://reactome.org/PathwayBrowser/#/R-RNO-2730886 Phosphorylation of SHC by SYK kinase IEA Rattus norvegicus A0A0G2K828 R-RNO-5690701 https://reactome.org/PathwayBrowser/#/R-RNO-5690701 SHP1 binds p-CD22 IEA Rattus norvegicus A0A0G2K828 R-RNO-5690702 https://reactome.org/PathwayBrowser/#/R-RNO-5690702 LYN phosphorylates CD22 IEA Rattus norvegicus A0A0G2K828 R-RNO-5690740 https://reactome.org/PathwayBrowser/#/R-RNO-5690740 CD22 binds B-cell receptor IEA Rattus norvegicus A0A0G2K828 R-RNO-8852266 https://reactome.org/PathwayBrowser/#/R-RNO-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Rattus norvegicus A0A0G2K828 R-RNO-8852481 https://reactome.org/PathwayBrowser/#/R-RNO-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Rattus norvegicus A0A0G2K828 R-RNO-8858428 https://reactome.org/PathwayBrowser/#/R-RNO-8858428 FCAMR binds IgA IEA Rattus norvegicus A0A0G2K828 R-RNO-8858498 https://reactome.org/PathwayBrowser/#/R-RNO-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Rattus norvegicus A0A0G2K828 R-RNO-9021306 https://reactome.org/PathwayBrowser/#/R-RNO-9021306 C1-Inh binds and inactivates C1r, C1s IEA Rattus norvegicus A0A0G2K828 R-RNO-9606151 https://reactome.org/PathwayBrowser/#/R-RNO-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Rattus norvegicus A0A0G2K828 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus A0A0G2K828 R-RNO-9724685 https://reactome.org/PathwayBrowser/#/R-RNO-9724685 IgE binds omalizumab IEA Rattus norvegicus A0A0G2K828 R-RNO-9725206 https://reactome.org/PathwayBrowser/#/R-RNO-9725206 IgE binds FCERI IEA Rattus norvegicus A0A0G2K828 R-RNO-983696 https://reactome.org/PathwayBrowser/#/R-RNO-983696 The Immunoglobulin of the BCR binds antigen IEA Rattus norvegicus A0A0G2K828 R-RNO-983700 https://reactome.org/PathwayBrowser/#/R-RNO-983700 SYK binds the activated BCR IEA Rattus norvegicus A0A0G2K828 R-RNO-983703 https://reactome.org/PathwayBrowser/#/R-RNO-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Rattus norvegicus A0A0G2K828 R-RNO-983707 https://reactome.org/PathwayBrowser/#/R-RNO-983707 SYK autophosphorylates at the activated BCR IEA Rattus norvegicus A0A0G2K836 R-RNO-5173005 https://reactome.org/PathwayBrowser/#/R-RNO-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Rattus norvegicus A0A0G2K836 R-RNO-5173192 https://reactome.org/PathwayBrowser/#/R-RNO-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Rattus norvegicus A0A0G2K849 R-RNO-109636 https://reactome.org/PathwayBrowser/#/R-RNO-109636 Recognition and Binding of Core Promoter Elements by TFIID IEA Rattus norvegicus A0A0G2K849 R-RNO-109637 https://reactome.org/PathwayBrowser/#/R-RNO-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Rattus norvegicus A0A0G2K849 R-RNO-109638 https://reactome.org/PathwayBrowser/#/R-RNO-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Rattus norvegicus A0A0G2K849 R-RNO-109639 https://reactome.org/PathwayBrowser/#/R-RNO-109639 Formation of the closed pre-initiation complex IEA Rattus norvegicus A0A0G2K849 R-RNO-6805399 https://reactome.org/PathwayBrowser/#/R-RNO-6805399 TAF1 phosphorylates TP53 IEA Rattus norvegicus A0A0G2K849 R-RNO-73946 https://reactome.org/PathwayBrowser/#/R-RNO-73946 Abortive initiation after formation of the first phosphodiester bond IEA Rattus norvegicus A0A0G2K849 R-RNO-75095 https://reactome.org/PathwayBrowser/#/R-RNO-75095 Binding of TFIIE to the growing preinitiation complex IEA Rattus norvegicus A0A0G2K849 R-RNO-75850 https://reactome.org/PathwayBrowser/#/R-RNO-75850 Addition of the third nucleotide on the nascent transcript IEA Rattus norvegicus A0A0G2K849 R-RNO-75856 https://reactome.org/PathwayBrowser/#/R-RNO-75856 Abortive Initiation Before Second Transition IEA Rattus norvegicus A0A0G2K849 R-RNO-75861 https://reactome.org/PathwayBrowser/#/R-RNO-75861 NTP Binds Active Site of RNA Polymerase II IEA Rattus norvegicus A0A0G2K849 R-RNO-75862 https://reactome.org/PathwayBrowser/#/R-RNO-75862 Fall Back to Closed Pre-initiation Complex IEA Rattus norvegicus A0A0G2K849 R-RNO-75864 https://reactome.org/PathwayBrowser/#/R-RNO-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Rattus norvegicus A0A0G2K849 R-RNO-75866 https://reactome.org/PathwayBrowser/#/R-RNO-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Rattus norvegicus A0A0G2K849 R-RNO-75869 https://reactome.org/PathwayBrowser/#/R-RNO-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Rattus norvegicus A0A0G2K849 R-RNO-75873 https://reactome.org/PathwayBrowser/#/R-RNO-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Rattus norvegicus A0A0G2K849 R-RNO-75949 https://reactome.org/PathwayBrowser/#/R-RNO-75949 RNA Polymerase II Promoter Opening: First Transition IEA Rattus norvegicus A0A0G2K849 R-RNO-9613494 https://reactome.org/PathwayBrowser/#/R-RNO-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Rattus norvegicus A0A0G2K849 R-RNO-9613497 https://reactome.org/PathwayBrowser/#/R-RNO-9613497 Unwinding DNA for the nascent transcript IEA Rattus norvegicus A0A0G2K857 R-RNO-2213248 https://reactome.org/PathwayBrowser/#/R-RNO-2213248 Transport of antigen loaded MHC II molecules to surface IEA Rattus norvegicus A0A0G2K857 R-RNO-6811423 https://reactome.org/PathwayBrowser/#/R-RNO-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Rattus norvegicus A0A0G2K857 R-RNO-6811426 https://reactome.org/PathwayBrowser/#/R-RNO-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Rattus norvegicus A0A0G2K857 R-RNO-983259 https://reactome.org/PathwayBrowser/#/R-RNO-983259 Kinesins move along microtubules consuming ATP IEA Rattus norvegicus A0A0G2K857 R-RNO-983266 https://reactome.org/PathwayBrowser/#/R-RNO-983266 Kinesins bind microtubules IEA Rattus norvegicus A0A0G2K860 R-RNO-205039 https://reactome.org/PathwayBrowser/#/R-RNO-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Rattus norvegicus A0A0G2K860 R-RNO-398184 https://reactome.org/PathwayBrowser/#/R-RNO-398184 LARG activation by G alpha 12/13 IEA Rattus norvegicus A0A0G2K860 R-RNO-398185 https://reactome.org/PathwayBrowser/#/R-RNO-398185 LARG binds plexin B1 IEA Rattus norvegicus A0A0G2K860 R-RNO-416588 https://reactome.org/PathwayBrowser/#/R-RNO-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Rattus norvegicus A0A0G2K860 R-RNO-416594 https://reactome.org/PathwayBrowser/#/R-RNO-416594 LARG and PDZ-RhoGEF binds to Plexin-B1 IEA Rattus norvegicus A0A0G2K860 R-RNO-419166 https://reactome.org/PathwayBrowser/#/R-RNO-419166 GEFs activate RhoA,B,C IEA Rattus norvegicus A0A0G2K860 R-RNO-8980691 https://reactome.org/PathwayBrowser/#/R-RNO-8980691 RHOA GEFs activate RHOA IEA Rattus norvegicus A0A0G2K860 R-RNO-9013023 https://reactome.org/PathwayBrowser/#/R-RNO-9013023 RHOB GEFs activate RHOB IEA Rattus norvegicus A0A0G2K860 R-RNO-9013159 https://reactome.org/PathwayBrowser/#/R-RNO-9013159 CDC42 GEFs activate CDC42 IEA Rattus norvegicus A0A0G2K865 R-RNO-421831 https://reactome.org/PathwayBrowser/#/R-RNO-421831 trans-Golgi Network Coat Assembly IEA Rattus norvegicus A0A0G2K865 R-RNO-421833 https://reactome.org/PathwayBrowser/#/R-RNO-421833 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture IEA Rattus norvegicus A0A0G2K865 R-RNO-421835 https://reactome.org/PathwayBrowser/#/R-RNO-421835 trans-Golgi Network Vesicle Scission IEA Rattus norvegicus A0A0G2K865 R-RNO-421836 https://reactome.org/PathwayBrowser/#/R-RNO-421836 trans-Golgi Network Derived Vesicle Uncoating IEA Rattus norvegicus A0A0G2K881 R-RNO-1236943 https://reactome.org/PathwayBrowser/#/R-RNO-1236943 Loading of antigen peptide onto MHC class I molecule IEA Rattus norvegicus A0A0G2K881 R-RNO-1236954 https://reactome.org/PathwayBrowser/#/R-RNO-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Rattus norvegicus A0A0G2K881 R-RNO-1236964 https://reactome.org/PathwayBrowser/#/R-RNO-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Rattus norvegicus A0A0G2K881 R-RNO-1236965 https://reactome.org/PathwayBrowser/#/R-RNO-1236965 Export of peptide loaded MHC class I complex to PM IEA Rattus norvegicus A0A0G2K881 R-RNO-198955 https://reactome.org/PathwayBrowser/#/R-RNO-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Rattus norvegicus A0A0G2K881 R-RNO-198958 https://reactome.org/PathwayBrowser/#/R-RNO-198958 KIR2DL2/3 interacting with HLA-C group 1 (Cw4) IEA Rattus norvegicus A0A0G2K881 R-RNO-199169 https://reactome.org/PathwayBrowser/#/R-RNO-199169 MHC Class I interacts with CD160 IEA Rattus norvegicus A0A0G2K881 R-RNO-199558 https://reactome.org/PathwayBrowser/#/R-RNO-199558 KIR2DL1 interacting with HLA-C group 2 (Cw3) IEA Rattus norvegicus A0A0G2K881 R-RNO-199566 https://reactome.org/PathwayBrowser/#/R-RNO-199566 KIR3DL1 interacting with HLA Bw4 IEA Rattus norvegicus A0A0G2K881 R-RNO-199583 https://reactome.org/PathwayBrowser/#/R-RNO-199583 KIR2DS2 interacting with HLA-C group 1 (Cw3) IEA Rattus norvegicus A0A0G2K881 R-RNO-199587 https://reactome.org/PathwayBrowser/#/R-RNO-199587 KIR2DS1 interacting with HLA-C group 2 (Cw4) IEA Rattus norvegicus A0A0G2K881 R-RNO-210298 https://reactome.org/PathwayBrowser/#/R-RNO-210298 Interaction of DAP12 and KIR3DS1 IEA Rattus norvegicus A0A0G2K881 R-RNO-210309 https://reactome.org/PathwayBrowser/#/R-RNO-210309 Interaction of DAP12 and KIR2DS2 IEA Rattus norvegicus A0A0G2K881 R-RNO-2272753 https://reactome.org/PathwayBrowser/#/R-RNO-2272753 Interaction of DAP12 and KIR2DS4 IEA Rattus norvegicus A0A0G2K881 R-RNO-2272795 https://reactome.org/PathwayBrowser/#/R-RNO-2272795 Interaction of DAP12 and KIR2DS1 IEA Rattus norvegicus A0A0G2K881 R-RNO-6798739 https://reactome.org/PathwayBrowser/#/R-RNO-6798739 Exocytosis of azurophil granule membrane proteins IEA Rattus norvegicus A0A0G2K881 R-RNO-6798743 https://reactome.org/PathwayBrowser/#/R-RNO-6798743 Exocytosis of secretory granule membrane proteins IEA Rattus norvegicus A0A0G2K881 R-RNO-8863973 https://reactome.org/PathwayBrowser/#/R-RNO-8863973 Fusion of ERC and phagosome IEA Rattus norvegicus A0A0G2K881 R-RNO-8951499 https://reactome.org/PathwayBrowser/#/R-RNO-8951499 Loading of antigenic peptides on to class I MHC IEA Rattus norvegicus A0A0G2K881 R-RNO-983138 https://reactome.org/PathwayBrowser/#/R-RNO-983138 Transport of MHC heterotrimer to ER exit site IEA Rattus norvegicus A0A0G2K881 R-RNO-983142 https://reactome.org/PathwayBrowser/#/R-RNO-983142 Formation of peptide loading complex (PLC) IEA Rattus norvegicus A0A0G2K881 R-RNO-983145 https://reactome.org/PathwayBrowser/#/R-RNO-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Rattus norvegicus A0A0G2K881 R-RNO-983146 https://reactome.org/PathwayBrowser/#/R-RNO-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Rattus norvegicus A0A0G2K881 R-RNO-983161 https://reactome.org/PathwayBrowser/#/R-RNO-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex IEA Rattus norvegicus A0A0G2K881 R-RNO-983421 https://reactome.org/PathwayBrowser/#/R-RNO-983421 Journey of cargo through Golgi complex IEA Rattus norvegicus A0A0G2K881 R-RNO-983422 https://reactome.org/PathwayBrowser/#/R-RNO-983422 Disassembly of COPII coated vesicle IEA Rattus norvegicus A0A0G2K881 R-RNO-983424 https://reactome.org/PathwayBrowser/#/R-RNO-983424 Budding of COPII coated vesicle IEA Rattus norvegicus A0A0G2K881 R-RNO-983425 https://reactome.org/PathwayBrowser/#/R-RNO-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Rattus norvegicus A0A0G2K881 R-RNO-983427 https://reactome.org/PathwayBrowser/#/R-RNO-983427 Expression of peptide bound class I MHC on cell surface IEA Rattus norvegicus A0A0G2K889 R-RNO-3788724 https://reactome.org/PathwayBrowser/#/R-RNO-3788724 Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 IEA Rattus norvegicus A0A0G2K889 R-RNO-3788725 https://reactome.org/PathwayBrowser/#/R-RNO-3788725 Cdh1:APC/C complex binds EHMT1:EHMT2 IEA Rattus norvegicus A0A0G2K889 R-RNO-3788745 https://reactome.org/PathwayBrowser/#/R-RNO-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Rattus norvegicus A0A0G2K889 R-RNO-3788748 https://reactome.org/PathwayBrowser/#/R-RNO-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Rattus norvegicus A0A0G2K889 R-RNO-5634729 https://reactome.org/PathwayBrowser/#/R-RNO-5634729 EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) IEA Rattus norvegicus A0A0G2K889 R-RNO-5634750 https://reactome.org/PathwayBrowser/#/R-RNO-5634750 EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) IEA Rattus norvegicus A0A0G2K889 R-RNO-6805755 https://reactome.org/PathwayBrowser/#/R-RNO-6805755 EHMT1:EHMT2 dimethylates TP53 IEA Rattus norvegicus A0A0G2K889 R-RNO-8953418 https://reactome.org/PathwayBrowser/#/R-RNO-8953418 EHMT1:EHMT2 complex binds E2F6.com-1 core IEA Rattus norvegicus A0A0G2K889 R-RNO-9007283 https://reactome.org/PathwayBrowser/#/R-RNO-9007283 CBX3 and PRC1.6 associate with E2F6.com-1 IEA Rattus norvegicus A0A0G2K8C5 R-RNO-9609921 https://reactome.org/PathwayBrowser/#/R-RNO-9609921 SGTA binds Tail-anchored protein IEA Rattus norvegicus A0A0G2K8C5 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2K8C5 R-RNO-983152 https://reactome.org/PathwayBrowser/#/R-RNO-983152 Transfer of ubiquitin from E1 to E2 IEA Rattus norvegicus A0A0G2K8C5 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2K8C5 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2K8C6 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2K8D1 R-RNO-6799350 https://reactome.org/PathwayBrowser/#/R-RNO-6799350 Exocytosis of specific granule membrane proteins IEA Rattus norvegicus A0A0G2K8D1 R-RNO-9013438 https://reactome.org/PathwayBrowser/#/R-RNO-9013438 RHOD binds effectors at the endosome membrane IEA Rattus norvegicus A0A0G2K8E5 R-RNO-6814549 https://reactome.org/PathwayBrowser/#/R-RNO-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Rattus norvegicus A0A0G2K8E5 R-RNO-6814555 https://reactome.org/PathwayBrowser/#/R-RNO-6814555 Integrator complex processes the 3' end of snRNA IEA Rattus norvegicus A0A0G2K8E5 R-RNO-6814559 https://reactome.org/PathwayBrowser/#/R-RNO-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Rattus norvegicus A0A0G2K8E5 R-RNO-6814885 https://reactome.org/PathwayBrowser/#/R-RNO-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Rattus norvegicus A0A0G2K8K8 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus A0A0G2K8K8 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus A0A0G2K8K8 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus A0A0G2K8K8 R-RNO-173626 https://reactome.org/PathwayBrowser/#/R-RNO-173626 Activation of C1r IEA Rattus norvegicus A0A0G2K8K8 R-RNO-173631 https://reactome.org/PathwayBrowser/#/R-RNO-173631 Activation of C1s IEA Rattus norvegicus A0A0G2K8K8 R-RNO-1861621 https://reactome.org/PathwayBrowser/#/R-RNO-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K8K8 R-RNO-199161 https://reactome.org/PathwayBrowser/#/R-RNO-199161 Fc gamma receptors interact with antigen-bound IgG IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2029268 https://reactome.org/PathwayBrowser/#/R-RNO-2029268 Phosphorylation and activation of PLCG IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2029270 https://reactome.org/PathwayBrowser/#/R-RNO-2029270 Recruitment of PLCgamma to membrane IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2029272 https://reactome.org/PathwayBrowser/#/R-RNO-2029272 Release of PLCG from FCGR IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2029273 https://reactome.org/PathwayBrowser/#/R-RNO-2029273 PI3K binds to p-6Y-SYK IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2029451 https://reactome.org/PathwayBrowser/#/R-RNO-2029451 Activation of RAC1 by VAV IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2029452 https://reactome.org/PathwayBrowser/#/R-RNO-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2029453 https://reactome.org/PathwayBrowser/#/R-RNO-2029453 Phosphorylation of VAV IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2029455 https://reactome.org/PathwayBrowser/#/R-RNO-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2029457 https://reactome.org/PathwayBrowser/#/R-RNO-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2029458 https://reactome.org/PathwayBrowser/#/R-RNO-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2029459 https://reactome.org/PathwayBrowser/#/R-RNO-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2029467 https://reactome.org/PathwayBrowser/#/R-RNO-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2029476 https://reactome.org/PathwayBrowser/#/R-RNO-2029476 Role of myosins in phagosome formation IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2203516 https://reactome.org/PathwayBrowser/#/R-RNO-2203516 Alpha-1-Microglobulin is cleaved IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2454192 https://reactome.org/PathwayBrowser/#/R-RNO-2454192 Allergen dependent IgE bound FCERI aggregation IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2454208 https://reactome.org/PathwayBrowser/#/R-RNO-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2454240 https://reactome.org/PathwayBrowser/#/R-RNO-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2730843 https://reactome.org/PathwayBrowser/#/R-RNO-2730843 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2730851 https://reactome.org/PathwayBrowser/#/R-RNO-2730851 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2730882 https://reactome.org/PathwayBrowser/#/R-RNO-2730882 Phosphorylation of PKC-theta IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2730884 https://reactome.org/PathwayBrowser/#/R-RNO-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Rattus norvegicus A0A0G2K8K8 R-RNO-2730886 https://reactome.org/PathwayBrowser/#/R-RNO-2730886 Phosphorylation of SHC by SYK kinase IEA Rattus norvegicus A0A0G2K8K8 R-RNO-5690701 https://reactome.org/PathwayBrowser/#/R-RNO-5690701 SHP1 binds p-CD22 IEA Rattus norvegicus A0A0G2K8K8 R-RNO-5690702 https://reactome.org/PathwayBrowser/#/R-RNO-5690702 LYN phosphorylates CD22 IEA Rattus norvegicus A0A0G2K8K8 R-RNO-5690740 https://reactome.org/PathwayBrowser/#/R-RNO-5690740 CD22 binds B-cell receptor IEA Rattus norvegicus A0A0G2K8K8 R-RNO-8852266 https://reactome.org/PathwayBrowser/#/R-RNO-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Rattus norvegicus A0A0G2K8K8 R-RNO-8852481 https://reactome.org/PathwayBrowser/#/R-RNO-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Rattus norvegicus A0A0G2K8K8 R-RNO-8858428 https://reactome.org/PathwayBrowser/#/R-RNO-8858428 FCAMR binds IgA IEA Rattus norvegicus A0A0G2K8K8 R-RNO-8858498 https://reactome.org/PathwayBrowser/#/R-RNO-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Rattus norvegicus A0A0G2K8K8 R-RNO-9021306 https://reactome.org/PathwayBrowser/#/R-RNO-9021306 C1-Inh binds and inactivates C1r, C1s IEA Rattus norvegicus A0A0G2K8K8 R-RNO-9606151 https://reactome.org/PathwayBrowser/#/R-RNO-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Rattus norvegicus A0A0G2K8K8 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus A0A0G2K8K8 R-RNO-9724685 https://reactome.org/PathwayBrowser/#/R-RNO-9724685 IgE binds omalizumab IEA Rattus norvegicus A0A0G2K8K8 R-RNO-9725206 https://reactome.org/PathwayBrowser/#/R-RNO-9725206 IgE binds FCERI IEA Rattus norvegicus A0A0G2K8K8 R-RNO-983696 https://reactome.org/PathwayBrowser/#/R-RNO-983696 The Immunoglobulin of the BCR binds antigen IEA Rattus norvegicus A0A0G2K8K8 R-RNO-983700 https://reactome.org/PathwayBrowser/#/R-RNO-983700 SYK binds the activated BCR IEA Rattus norvegicus A0A0G2K8K8 R-RNO-983703 https://reactome.org/PathwayBrowser/#/R-RNO-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Rattus norvegicus A0A0G2K8K8 R-RNO-983707 https://reactome.org/PathwayBrowser/#/R-RNO-983707 SYK autophosphorylates at the activated BCR IEA Rattus norvegicus A0A0G2K8N4 R-RNO-1650808 https://reactome.org/PathwayBrowser/#/R-RNO-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Rattus norvegicus A0A0G2K8N4 R-RNO-1980233 https://reactome.org/PathwayBrowser/#/R-RNO-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Rattus norvegicus A0A0G2K8N4 R-RNO-1981104 https://reactome.org/PathwayBrowser/#/R-RNO-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Rattus norvegicus A0A0G2K8N4 R-RNO-1981120 https://reactome.org/PathwayBrowser/#/R-RNO-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Rattus norvegicus A0A0G2K8N4 R-RNO-1981128 https://reactome.org/PathwayBrowser/#/R-RNO-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Rattus norvegicus A0A0G2K8N4 R-RNO-1981157 https://reactome.org/PathwayBrowser/#/R-RNO-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Rattus norvegicus A0A0G2K8N4 R-RNO-2002460 https://reactome.org/PathwayBrowser/#/R-RNO-2002460 P4HB binds Collagen chains IEA Rattus norvegicus A0A0G2K8N4 R-RNO-2089971 https://reactome.org/PathwayBrowser/#/R-RNO-2089971 Secretion of collagens IEA Rattus norvegicus A0A0G2K8N4 R-RNO-2152276 https://reactome.org/PathwayBrowser/#/R-RNO-2152276 Secretion of transmembrane collagens IEA Rattus norvegicus A0A0G2K8N4 R-RNO-2471842 https://reactome.org/PathwayBrowser/#/R-RNO-2471842 Collagen type XXV ectomain shedding IEA Rattus norvegicus A0A0G2K8N4 R-RNO-8944250 https://reactome.org/PathwayBrowser/#/R-RNO-8944250 Association of procollagen type XXV IEA Rattus norvegicus A0A0G2K8N4 R-RNO-8944254 https://reactome.org/PathwayBrowser/#/R-RNO-8944254 Association of procollagen type XXVI IEA Rattus norvegicus A0A0G2K8N4 R-RNO-8948219 https://reactome.org/PathwayBrowser/#/R-RNO-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus A0A0G2K8N4 R-RNO-8948222 https://reactome.org/PathwayBrowser/#/R-RNO-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K8N4 R-RNO-8948224 https://reactome.org/PathwayBrowser/#/R-RNO-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K8N4 R-RNO-8948228 https://reactome.org/PathwayBrowser/#/R-RNO-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Rattus norvegicus A0A0G2K8N4 R-RNO-8948231 https://reactome.org/PathwayBrowser/#/R-RNO-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K8N4 R-RNO-8948232 https://reactome.org/PathwayBrowser/#/R-RNO-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Rattus norvegicus A0A0G2K8N4 R-RNO-8948234 https://reactome.org/PathwayBrowser/#/R-RNO-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Rattus norvegicus A0A0G2K8R3 R-RNO-8952618 https://reactome.org/PathwayBrowser/#/R-RNO-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2K8R3 R-RNO-8952620 https://reactome.org/PathwayBrowser/#/R-RNO-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2K8R3 R-RNO-8955241 https://reactome.org/PathwayBrowser/#/R-RNO-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Rattus norvegicus A0A0G2K8R3 R-RNO-8955289 https://reactome.org/PathwayBrowser/#/R-RNO-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Rattus norvegicus A0A0G2K8R3 R-RNO-8956040 https://reactome.org/PathwayBrowser/#/R-RNO-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Rattus norvegicus A0A0G2K8R3 R-RNO-8956200 https://reactome.org/PathwayBrowser/#/R-RNO-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2K8R3 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2K8R3 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus A0A0G2K8R3 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2K8R3 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2K8S8 R-RNO-5628905 https://reactome.org/PathwayBrowser/#/R-RNO-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Rattus norvegicus A0A0G2K8T1 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2K8T1 R-RNO-9842833 https://reactome.org/PathwayBrowser/#/R-RNO-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Rattus norvegicus A0A0G2K8T1 R-RNO-9842835 https://reactome.org/PathwayBrowser/#/R-RNO-9842835 KRAB-ZFP binds retroelement DNA in chromatin IEA Rattus norvegicus A0A0G2K8T1 R-RNO-9842839 https://reactome.org/PathwayBrowser/#/R-RNO-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Rattus norvegicus A0A0G2K8T1 R-RNO-9843978 https://reactome.org/PathwayBrowser/#/R-RNO-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Rattus norvegicus A0A0G2K8U0 R-RNO-73757 https://reactome.org/PathwayBrowser/#/R-RNO-73757 Binding of RRN3 to RNA Polymerase I IEA Rattus norvegicus A0A0G2K8U0 R-RNO-73758 https://reactome.org/PathwayBrowser/#/R-RNO-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Rattus norvegicus A0A0G2K8U0 R-RNO-73769 https://reactome.org/PathwayBrowser/#/R-RNO-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Rattus norvegicus A0A0G2K8V3 R-RNO-159101 https://reactome.org/PathwayBrowser/#/R-RNO-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Rattus norvegicus A0A0G2K8V3 R-RNO-72180 https://reactome.org/PathwayBrowser/#/R-RNO-72180 Cleavage of mRNA at the 3'-end IEA Rattus norvegicus A0A0G2K8V3 R-RNO-72185 https://reactome.org/PathwayBrowser/#/R-RNO-72185 mRNA polyadenylation IEA Rattus norvegicus A0A0G2K8X5 R-RNO-1964501 https://reactome.org/PathwayBrowser/#/R-RNO-1964501 Addition of galactose to Core 6 glycoprotein IEA Rattus norvegicus A0A0G2K8X5 R-RNO-1964505 https://reactome.org/PathwayBrowser/#/R-RNO-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Rattus norvegicus A0A0G2K8X5 R-RNO-5694487 https://reactome.org/PathwayBrowser/#/R-RNO-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Rattus norvegicus A0A0G2K8X5 R-RNO-6786012 https://reactome.org/PathwayBrowser/#/R-RNO-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Rattus norvegicus A0A0G2K8X5 R-RNO-913675 https://reactome.org/PathwayBrowser/#/R-RNO-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Rattus norvegicus A0A0G2K8X5 R-RNO-914005 https://reactome.org/PathwayBrowser/#/R-RNO-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Rattus norvegicus A0A0G2K8X5 R-RNO-914006 https://reactome.org/PathwayBrowser/#/R-RNO-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Rattus norvegicus A0A0G2K8X5 R-RNO-914008 https://reactome.org/PathwayBrowser/#/R-RNO-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Rattus norvegicus A0A0G2K8X5 R-RNO-914010 https://reactome.org/PathwayBrowser/#/R-RNO-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Rattus norvegicus A0A0G2K8X5 R-RNO-914012 https://reactome.org/PathwayBrowser/#/R-RNO-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Rattus norvegicus A0A0G2K8X5 R-RNO-914017 https://reactome.org/PathwayBrowser/#/R-RNO-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Rattus norvegicus A0A0G2K8X5 R-RNO-914018 https://reactome.org/PathwayBrowser/#/R-RNO-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Rattus norvegicus A0A0G2K8X5 R-RNO-977071 https://reactome.org/PathwayBrowser/#/R-RNO-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Rattus norvegicus A0A0G2K8X5 R-RNO-981497 https://reactome.org/PathwayBrowser/#/R-RNO-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Rattus norvegicus A0A0G2K8X5 R-RNO-981809 https://reactome.org/PathwayBrowser/#/R-RNO-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Rattus norvegicus A0A0G2K8X5 R-RNO-981814 https://reactome.org/PathwayBrowser/#/R-RNO-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Rattus norvegicus A0A0G2K8Z9 R-RNO-2213248 https://reactome.org/PathwayBrowser/#/R-RNO-2213248 Transport of antigen loaded MHC II molecules to surface IEA Rattus norvegicus A0A0G2K8Z9 R-RNO-6811423 https://reactome.org/PathwayBrowser/#/R-RNO-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Rattus norvegicus A0A0G2K8Z9 R-RNO-6811426 https://reactome.org/PathwayBrowser/#/R-RNO-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Rattus norvegicus A0A0G2K8Z9 R-RNO-983259 https://reactome.org/PathwayBrowser/#/R-RNO-983259 Kinesins move along microtubules consuming ATP IEA Rattus norvegicus A0A0G2K8Z9 R-RNO-983266 https://reactome.org/PathwayBrowser/#/R-RNO-983266 Kinesins bind microtubules IEA Rattus norvegicus A0A0G2K929 R-RNO-2574840 https://reactome.org/PathwayBrowser/#/R-RNO-2574840 AJUBA facilitates AURKA autophosphorylation IEA Rattus norvegicus A0A0G2K929 R-RNO-2574845 https://reactome.org/PathwayBrowser/#/R-RNO-2574845 AJUBA binds centrosome-associated AURKA IEA Rattus norvegicus A0A0G2K929 R-RNO-3000310 https://reactome.org/PathwayBrowser/#/R-RNO-3000310 AURKA phosphorylates PLK1 IEA Rattus norvegicus A0A0G2K929 R-RNO-3000319 https://reactome.org/PathwayBrowser/#/R-RNO-3000319 BORA binds PLK1 and AURKA IEA Rattus norvegicus A0A0G2K929 R-RNO-380272 https://reactome.org/PathwayBrowser/#/R-RNO-380272 Plk1-mediated phosphorylation of Nlp IEA Rattus norvegicus A0A0G2K929 R-RNO-380283 https://reactome.org/PathwayBrowser/#/R-RNO-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Rattus norvegicus A0A0G2K929 R-RNO-380294 https://reactome.org/PathwayBrowser/#/R-RNO-380294 Loss of C-Nap-1 from centrosomes IEA Rattus norvegicus A0A0G2K929 R-RNO-380303 https://reactome.org/PathwayBrowser/#/R-RNO-380303 Dissociation of Phospho-Nlp from the centrosome IEA Rattus norvegicus A0A0G2K929 R-RNO-380311 https://reactome.org/PathwayBrowser/#/R-RNO-380311 Recruitment of Plk1 to centrosomes IEA Rattus norvegicus A0A0G2K929 R-RNO-380316 https://reactome.org/PathwayBrowser/#/R-RNO-380316 Association of NuMA with microtubules IEA Rattus norvegicus A0A0G2K929 R-RNO-380455 https://reactome.org/PathwayBrowser/#/R-RNO-380455 Recruitment of CDK11p58 to the centrosomes IEA Rattus norvegicus A0A0G2K929 R-RNO-380508 https://reactome.org/PathwayBrowser/#/R-RNO-380508 Translocation of NuMA to the centrosomes IEA Rattus norvegicus A0A0G2K929 R-RNO-5617816 https://reactome.org/PathwayBrowser/#/R-RNO-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Rattus norvegicus A0A0G2K929 R-RNO-5626220 https://reactome.org/PathwayBrowser/#/R-RNO-5626220 C2CD3 binds the mother centriole IEA Rattus norvegicus A0A0G2K929 R-RNO-5626223 https://reactome.org/PathwayBrowser/#/R-RNO-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Rattus norvegicus A0A0G2K929 R-RNO-5626227 https://reactome.org/PathwayBrowser/#/R-RNO-5626227 CP110 and CEP97 dissociate from the centriole IEA Rattus norvegicus A0A0G2K929 R-RNO-5626228 https://reactome.org/PathwayBrowser/#/R-RNO-5626228 The distal appendage proteins recruit TTBK2 IEA Rattus norvegicus A0A0G2K929 R-RNO-5626681 https://reactome.org/PathwayBrowser/#/R-RNO-5626681 Recruitment of transition zone proteins IEA Rattus norvegicus A0A0G2K929 R-RNO-5626699 https://reactome.org/PathwayBrowser/#/R-RNO-5626699 MARK4 binds ODF2 in the centriole IEA Rattus norvegicus A0A0G2K929 R-RNO-5638009 https://reactome.org/PathwayBrowser/#/R-RNO-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Rattus norvegicus A0A0G2K929 R-RNO-6798749 https://reactome.org/PathwayBrowser/#/R-RNO-6798749 Exocytosis of specific granule lumen proteins IEA Rattus norvegicus A0A0G2K929 R-RNO-8853419 https://reactome.org/PathwayBrowser/#/R-RNO-8853419 TPX2 promotes AURKA autophosphorylation IEA Rattus norvegicus A0A0G2K931 R-RNO-977333 https://reactome.org/PathwayBrowser/#/R-RNO-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA IEA Rattus norvegicus A0A0G2K950 R-RNO-174389 https://reactome.org/PathwayBrowser/#/R-RNO-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Rattus norvegicus A0A0G2K950 R-RNO-174392 https://reactome.org/PathwayBrowser/#/R-RNO-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Rattus norvegicus A0A0G2K951 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2K980 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus A0A0G2K980 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus A0A0G2K980 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus A0A0G2K980 R-RNO-173626 https://reactome.org/PathwayBrowser/#/R-RNO-173626 Activation of C1r IEA Rattus norvegicus A0A0G2K980 R-RNO-173631 https://reactome.org/PathwayBrowser/#/R-RNO-173631 Activation of C1s IEA Rattus norvegicus A0A0G2K980 R-RNO-1861621 https://reactome.org/PathwayBrowser/#/R-RNO-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K980 R-RNO-199161 https://reactome.org/PathwayBrowser/#/R-RNO-199161 Fc gamma receptors interact with antigen-bound IgG IEA Rattus norvegicus A0A0G2K980 R-RNO-2029268 https://reactome.org/PathwayBrowser/#/R-RNO-2029268 Phosphorylation and activation of PLCG IEA Rattus norvegicus A0A0G2K980 R-RNO-2029270 https://reactome.org/PathwayBrowser/#/R-RNO-2029270 Recruitment of PLCgamma to membrane IEA Rattus norvegicus A0A0G2K980 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K980 R-RNO-2029272 https://reactome.org/PathwayBrowser/#/R-RNO-2029272 Release of PLCG from FCGR IEA Rattus norvegicus A0A0G2K980 R-RNO-2029273 https://reactome.org/PathwayBrowser/#/R-RNO-2029273 PI3K binds to p-6Y-SYK IEA Rattus norvegicus A0A0G2K980 R-RNO-2029451 https://reactome.org/PathwayBrowser/#/R-RNO-2029451 Activation of RAC1 by VAV IEA Rattus norvegicus A0A0G2K980 R-RNO-2029452 https://reactome.org/PathwayBrowser/#/R-RNO-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Rattus norvegicus A0A0G2K980 R-RNO-2029453 https://reactome.org/PathwayBrowser/#/R-RNO-2029453 Phosphorylation of VAV IEA Rattus norvegicus A0A0G2K980 R-RNO-2029455 https://reactome.org/PathwayBrowser/#/R-RNO-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K980 R-RNO-2029457 https://reactome.org/PathwayBrowser/#/R-RNO-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K980 R-RNO-2029458 https://reactome.org/PathwayBrowser/#/R-RNO-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Rattus norvegicus A0A0G2K980 R-RNO-2029459 https://reactome.org/PathwayBrowser/#/R-RNO-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Rattus norvegicus A0A0G2K980 R-RNO-2029467 https://reactome.org/PathwayBrowser/#/R-RNO-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Rattus norvegicus A0A0G2K980 R-RNO-2029476 https://reactome.org/PathwayBrowser/#/R-RNO-2029476 Role of myosins in phagosome formation IEA Rattus norvegicus A0A0G2K980 R-RNO-2203516 https://reactome.org/PathwayBrowser/#/R-RNO-2203516 Alpha-1-Microglobulin is cleaved IEA Rattus norvegicus A0A0G2K980 R-RNO-2454192 https://reactome.org/PathwayBrowser/#/R-RNO-2454192 Allergen dependent IgE bound FCERI aggregation IEA Rattus norvegicus A0A0G2K980 R-RNO-2454208 https://reactome.org/PathwayBrowser/#/R-RNO-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Rattus norvegicus A0A0G2K980 R-RNO-2454240 https://reactome.org/PathwayBrowser/#/R-RNO-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Rattus norvegicus A0A0G2K980 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus A0A0G2K980 R-RNO-2730843 https://reactome.org/PathwayBrowser/#/R-RNO-2730843 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus A0A0G2K980 R-RNO-2730851 https://reactome.org/PathwayBrowser/#/R-RNO-2730851 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus A0A0G2K980 R-RNO-2730882 https://reactome.org/PathwayBrowser/#/R-RNO-2730882 Phosphorylation of PKC-theta IEA Rattus norvegicus A0A0G2K980 R-RNO-2730884 https://reactome.org/PathwayBrowser/#/R-RNO-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Rattus norvegicus A0A0G2K980 R-RNO-2730886 https://reactome.org/PathwayBrowser/#/R-RNO-2730886 Phosphorylation of SHC by SYK kinase IEA Rattus norvegicus A0A0G2K980 R-RNO-5690701 https://reactome.org/PathwayBrowser/#/R-RNO-5690701 SHP1 binds p-CD22 IEA Rattus norvegicus A0A0G2K980 R-RNO-5690702 https://reactome.org/PathwayBrowser/#/R-RNO-5690702 LYN phosphorylates CD22 IEA Rattus norvegicus A0A0G2K980 R-RNO-5690740 https://reactome.org/PathwayBrowser/#/R-RNO-5690740 CD22 binds B-cell receptor IEA Rattus norvegicus A0A0G2K980 R-RNO-8852266 https://reactome.org/PathwayBrowser/#/R-RNO-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Rattus norvegicus A0A0G2K980 R-RNO-8852481 https://reactome.org/PathwayBrowser/#/R-RNO-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Rattus norvegicus A0A0G2K980 R-RNO-8858428 https://reactome.org/PathwayBrowser/#/R-RNO-8858428 FCAMR binds IgA IEA Rattus norvegicus A0A0G2K980 R-RNO-8858498 https://reactome.org/PathwayBrowser/#/R-RNO-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Rattus norvegicus A0A0G2K980 R-RNO-9021306 https://reactome.org/PathwayBrowser/#/R-RNO-9021306 C1-Inh binds and inactivates C1r, C1s IEA Rattus norvegicus A0A0G2K980 R-RNO-9606151 https://reactome.org/PathwayBrowser/#/R-RNO-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Rattus norvegicus A0A0G2K980 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus A0A0G2K980 R-RNO-9724685 https://reactome.org/PathwayBrowser/#/R-RNO-9724685 IgE binds omalizumab IEA Rattus norvegicus A0A0G2K980 R-RNO-9725206 https://reactome.org/PathwayBrowser/#/R-RNO-9725206 IgE binds FCERI IEA Rattus norvegicus A0A0G2K980 R-RNO-983696 https://reactome.org/PathwayBrowser/#/R-RNO-983696 The Immunoglobulin of the BCR binds antigen IEA Rattus norvegicus A0A0G2K980 R-RNO-983700 https://reactome.org/PathwayBrowser/#/R-RNO-983700 SYK binds the activated BCR IEA Rattus norvegicus A0A0G2K980 R-RNO-983703 https://reactome.org/PathwayBrowser/#/R-RNO-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Rattus norvegicus A0A0G2K980 R-RNO-983707 https://reactome.org/PathwayBrowser/#/R-RNO-983707 SYK autophosphorylates at the activated BCR IEA Rattus norvegicus A0A0G2K999 R-RNO-373741 https://reactome.org/PathwayBrowser/#/R-RNO-373741 SDK2 homophillic interaction IEA Rattus norvegicus A0A0G2K9A7 R-RNO-6791221 https://reactome.org/PathwayBrowser/#/R-RNO-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA IEA Rattus norvegicus A0A0G2K9A7 R-RNO-6791222 https://reactome.org/PathwayBrowser/#/R-RNO-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Rattus norvegicus A0A0G2K9A7 R-RNO-6791227 https://reactome.org/PathwayBrowser/#/R-RNO-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Rattus norvegicus A0A0G2K9A9 R-RNO-8952618 https://reactome.org/PathwayBrowser/#/R-RNO-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2K9A9 R-RNO-8952620 https://reactome.org/PathwayBrowser/#/R-RNO-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2K9A9 R-RNO-8955241 https://reactome.org/PathwayBrowser/#/R-RNO-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Rattus norvegicus A0A0G2K9A9 R-RNO-8955289 https://reactome.org/PathwayBrowser/#/R-RNO-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Rattus norvegicus A0A0G2K9A9 R-RNO-8956040 https://reactome.org/PathwayBrowser/#/R-RNO-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Rattus norvegicus A0A0G2K9A9 R-RNO-8956200 https://reactome.org/PathwayBrowser/#/R-RNO-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2K9A9 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2K9A9 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus A0A0G2K9A9 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2K9A9 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2K9D9 R-RNO-5617816 https://reactome.org/PathwayBrowser/#/R-RNO-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Rattus norvegicus A0A0G2K9D9 R-RNO-5626681 https://reactome.org/PathwayBrowser/#/R-RNO-5626681 Recruitment of transition zone proteins IEA Rattus norvegicus A0A0G2K9D9 R-RNO-5638009 https://reactome.org/PathwayBrowser/#/R-RNO-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Rattus norvegicus A0A0G2K9G3 R-RNO-5419261 https://reactome.org/PathwayBrowser/#/R-RNO-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Rattus norvegicus A0A0G2K9G3 R-RNO-5419264 https://reactome.org/PathwayBrowser/#/R-RNO-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Rattus norvegicus A0A0G2K9G3 R-RNO-5419271 https://reactome.org/PathwayBrowser/#/R-RNO-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Rattus norvegicus A0A0G2K9G3 R-RNO-5419273 https://reactome.org/PathwayBrowser/#/R-RNO-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Rattus norvegicus A0A0G2K9G3 R-RNO-5419281 https://reactome.org/PathwayBrowser/#/R-RNO-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Rattus norvegicus A0A0G2K9H2 R-RNO-6798751 https://reactome.org/PathwayBrowser/#/R-RNO-6798751 Exocytosis of azurophil granule lumen proteins IEA Rattus norvegicus A0A0G2K9K4 R-RNO-203973 https://reactome.org/PathwayBrowser/#/R-RNO-203973 Vesicle budding IEA Rattus norvegicus A0A0G2K9K4 R-RNO-204008 https://reactome.org/PathwayBrowser/#/R-RNO-204008 SEC31:SEC13 and v-SNARE recruitment IEA Rattus norvegicus A0A0G2K9K4 R-RNO-5694417 https://reactome.org/PathwayBrowser/#/R-RNO-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Rattus norvegicus A0A0G2K9L1 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus A0A0G2K9L1 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus A0A0G2K9L1 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus A0A0G2K9L1 R-RNO-173626 https://reactome.org/PathwayBrowser/#/R-RNO-173626 Activation of C1r IEA Rattus norvegicus A0A0G2K9L1 R-RNO-173631 https://reactome.org/PathwayBrowser/#/R-RNO-173631 Activation of C1s IEA Rattus norvegicus A0A0G2K9L1 R-RNO-1861621 https://reactome.org/PathwayBrowser/#/R-RNO-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K9L1 R-RNO-199161 https://reactome.org/PathwayBrowser/#/R-RNO-199161 Fc gamma receptors interact with antigen-bound IgG IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2029268 https://reactome.org/PathwayBrowser/#/R-RNO-2029268 Phosphorylation and activation of PLCG IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2029270 https://reactome.org/PathwayBrowser/#/R-RNO-2029270 Recruitment of PLCgamma to membrane IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2029272 https://reactome.org/PathwayBrowser/#/R-RNO-2029272 Release of PLCG from FCGR IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2029273 https://reactome.org/PathwayBrowser/#/R-RNO-2029273 PI3K binds to p-6Y-SYK IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2029451 https://reactome.org/PathwayBrowser/#/R-RNO-2029451 Activation of RAC1 by VAV IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2029452 https://reactome.org/PathwayBrowser/#/R-RNO-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2029453 https://reactome.org/PathwayBrowser/#/R-RNO-2029453 Phosphorylation of VAV IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2029455 https://reactome.org/PathwayBrowser/#/R-RNO-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2029457 https://reactome.org/PathwayBrowser/#/R-RNO-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2029458 https://reactome.org/PathwayBrowser/#/R-RNO-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2029459 https://reactome.org/PathwayBrowser/#/R-RNO-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2029467 https://reactome.org/PathwayBrowser/#/R-RNO-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2029476 https://reactome.org/PathwayBrowser/#/R-RNO-2029476 Role of myosins in phagosome formation IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2203516 https://reactome.org/PathwayBrowser/#/R-RNO-2203516 Alpha-1-Microglobulin is cleaved IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2454192 https://reactome.org/PathwayBrowser/#/R-RNO-2454192 Allergen dependent IgE bound FCERI aggregation IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2454208 https://reactome.org/PathwayBrowser/#/R-RNO-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2454240 https://reactome.org/PathwayBrowser/#/R-RNO-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2730843 https://reactome.org/PathwayBrowser/#/R-RNO-2730843 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2730851 https://reactome.org/PathwayBrowser/#/R-RNO-2730851 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2730882 https://reactome.org/PathwayBrowser/#/R-RNO-2730882 Phosphorylation of PKC-theta IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2730884 https://reactome.org/PathwayBrowser/#/R-RNO-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Rattus norvegicus A0A0G2K9L1 R-RNO-2730886 https://reactome.org/PathwayBrowser/#/R-RNO-2730886 Phosphorylation of SHC by SYK kinase IEA Rattus norvegicus A0A0G2K9L1 R-RNO-5690701 https://reactome.org/PathwayBrowser/#/R-RNO-5690701 SHP1 binds p-CD22 IEA Rattus norvegicus A0A0G2K9L1 R-RNO-5690702 https://reactome.org/PathwayBrowser/#/R-RNO-5690702 LYN phosphorylates CD22 IEA Rattus norvegicus A0A0G2K9L1 R-RNO-5690740 https://reactome.org/PathwayBrowser/#/R-RNO-5690740 CD22 binds B-cell receptor IEA Rattus norvegicus A0A0G2K9L1 R-RNO-8852266 https://reactome.org/PathwayBrowser/#/R-RNO-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Rattus norvegicus A0A0G2K9L1 R-RNO-8852481 https://reactome.org/PathwayBrowser/#/R-RNO-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Rattus norvegicus A0A0G2K9L1 R-RNO-8858428 https://reactome.org/PathwayBrowser/#/R-RNO-8858428 FCAMR binds IgA IEA Rattus norvegicus A0A0G2K9L1 R-RNO-9021306 https://reactome.org/PathwayBrowser/#/R-RNO-9021306 C1-Inh binds and inactivates C1r, C1s IEA Rattus norvegicus A0A0G2K9L1 R-RNO-9606151 https://reactome.org/PathwayBrowser/#/R-RNO-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Rattus norvegicus A0A0G2K9L1 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus A0A0G2K9L1 R-RNO-9724685 https://reactome.org/PathwayBrowser/#/R-RNO-9724685 IgE binds omalizumab IEA Rattus norvegicus A0A0G2K9L1 R-RNO-9725206 https://reactome.org/PathwayBrowser/#/R-RNO-9725206 IgE binds FCERI IEA Rattus norvegicus A0A0G2K9L1 R-RNO-983696 https://reactome.org/PathwayBrowser/#/R-RNO-983696 The Immunoglobulin of the BCR binds antigen IEA Rattus norvegicus A0A0G2K9L1 R-RNO-983700 https://reactome.org/PathwayBrowser/#/R-RNO-983700 SYK binds the activated BCR IEA Rattus norvegicus A0A0G2K9L1 R-RNO-983703 https://reactome.org/PathwayBrowser/#/R-RNO-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Rattus norvegicus A0A0G2K9L1 R-RNO-983707 https://reactome.org/PathwayBrowser/#/R-RNO-983707 SYK autophosphorylates at the activated BCR IEA Rattus norvegicus A0A0G2K9M2 R-RNO-975040 https://reactome.org/PathwayBrowser/#/R-RNO-975040 KRAB-ZNF / KAP Interaction IEA Rattus norvegicus A0A0G2K9M5 R-RNO-421831 https://reactome.org/PathwayBrowser/#/R-RNO-421831 trans-Golgi Network Coat Assembly IEA Rattus norvegicus A0A0G2K9M5 R-RNO-421833 https://reactome.org/PathwayBrowser/#/R-RNO-421833 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture IEA Rattus norvegicus A0A0G2K9M5 R-RNO-421835 https://reactome.org/PathwayBrowser/#/R-RNO-421835 trans-Golgi Network Vesicle Scission IEA Rattus norvegicus A0A0G2K9M5 R-RNO-421836 https://reactome.org/PathwayBrowser/#/R-RNO-421836 trans-Golgi Network Derived Vesicle Uncoating IEA Rattus norvegicus A0A0G2K9P5 R-RNO-6809006 https://reactome.org/PathwayBrowser/#/R-RNO-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Rattus norvegicus A0A0G2K9P5 R-RNO-6809010 https://reactome.org/PathwayBrowser/#/R-RNO-6809010 COPI vesicle uncoating IEA Rattus norvegicus A0A0G2K9P5 R-RNO-6809011 https://reactome.org/PathwayBrowser/#/R-RNO-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Rattus norvegicus A0A0G2K9P5 R-RNO-6811431 https://reactome.org/PathwayBrowser/#/R-RNO-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Rattus norvegicus A0A0G2K9P5 R-RNO-6811433 https://reactome.org/PathwayBrowser/#/R-RNO-6811433 The COG tethering complex interacts with numerous SNAREs at the Golgi membrane IEA Rattus norvegicus A0A0G2K9P5 R-RNO-6814682 https://reactome.org/PathwayBrowser/#/R-RNO-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Rattus norvegicus A0A0G2K9P5 R-RNO-8849748 https://reactome.org/PathwayBrowser/#/R-RNO-8849748 The COG complex binds RABs at the Golgi membrane IEA Rattus norvegicus A0A0G2K9S8 R-RNO-1592387 https://reactome.org/PathwayBrowser/#/R-RNO-1592387 Fibulin binds elastic fibres IEA Rattus norvegicus A0A0G2K9S8 R-RNO-2129353 https://reactome.org/PathwayBrowser/#/R-RNO-2129353 Tropoelastin associates with microfibrils IEA Rattus norvegicus A0A0G2K9S8 R-RNO-2129375 https://reactome.org/PathwayBrowser/#/R-RNO-2129375 Elastin cross-linking by lysyl oxidase IEA Rattus norvegicus A0A0G2K9S8 R-RNO-2129385 https://reactome.org/PathwayBrowser/#/R-RNO-2129385 MFAP2, MFAP5 bind microfibrils IEA Rattus norvegicus A0A0G2K9S8 R-RNO-2161282 https://reactome.org/PathwayBrowser/#/R-RNO-2161282 Elastic fibres bind associated proteins IEA Rattus norvegicus A0A0G2K9U6 R-RNO-5678490 https://reactome.org/PathwayBrowser/#/R-RNO-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Rattus norvegicus A0A0G2K9U6 R-RNO-5679255 https://reactome.org/PathwayBrowser/#/R-RNO-5679255 WIPI2 binds ATG12:ATG5:ATG16L IEA Rattus norvegicus A0A0G2K9U6 R-RNO-5682012 https://reactome.org/PathwayBrowser/#/R-RNO-5682012 ATG5:ATG12 binds ATG16L1 IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-1112666 https://reactome.org/PathwayBrowser/#/R-RNO-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-166753 https://reactome.org/PathwayBrowser/#/R-RNO-166753 Conversion of C4 into C4a and C4b IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-166792 https://reactome.org/PathwayBrowser/#/R-RNO-166792 Conversion of C2 into C2a and C2b IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-173626 https://reactome.org/PathwayBrowser/#/R-RNO-173626 Activation of C1r IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-173631 https://reactome.org/PathwayBrowser/#/R-RNO-173631 Activation of C1s IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-1861621 https://reactome.org/PathwayBrowser/#/R-RNO-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-199161 https://reactome.org/PathwayBrowser/#/R-RNO-199161 Fc gamma receptors interact with antigen-bound IgG IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2029268 https://reactome.org/PathwayBrowser/#/R-RNO-2029268 Phosphorylation and activation of PLCG IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2029270 https://reactome.org/PathwayBrowser/#/R-RNO-2029270 Recruitment of PLCgamma to membrane IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2029271 https://reactome.org/PathwayBrowser/#/R-RNO-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2029272 https://reactome.org/PathwayBrowser/#/R-RNO-2029272 Release of PLCG from FCGR IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2029273 https://reactome.org/PathwayBrowser/#/R-RNO-2029273 PI3K binds to p-6Y-SYK IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2029451 https://reactome.org/PathwayBrowser/#/R-RNO-2029451 Activation of RAC1 by VAV IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2029452 https://reactome.org/PathwayBrowser/#/R-RNO-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2029453 https://reactome.org/PathwayBrowser/#/R-RNO-2029453 Phosphorylation of VAV IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2029455 https://reactome.org/PathwayBrowser/#/R-RNO-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2029457 https://reactome.org/PathwayBrowser/#/R-RNO-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2029458 https://reactome.org/PathwayBrowser/#/R-RNO-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2029459 https://reactome.org/PathwayBrowser/#/R-RNO-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2029467 https://reactome.org/PathwayBrowser/#/R-RNO-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2029476 https://reactome.org/PathwayBrowser/#/R-RNO-2029476 Role of myosins in phagosome formation IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2203516 https://reactome.org/PathwayBrowser/#/R-RNO-2203516 Alpha-1-Microglobulin is cleaved IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2454192 https://reactome.org/PathwayBrowser/#/R-RNO-2454192 Allergen dependent IgE bound FCERI aggregation IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2454208 https://reactome.org/PathwayBrowser/#/R-RNO-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2454240 https://reactome.org/PathwayBrowser/#/R-RNO-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2730833 https://reactome.org/PathwayBrowser/#/R-RNO-2730833 Phosphorylation of TEC kinases by p-SYK IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2730843 https://reactome.org/PathwayBrowser/#/R-RNO-2730843 Phosphorylation of LAT by p-SYK IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2730851 https://reactome.org/PathwayBrowser/#/R-RNO-2730851 Phosphorylation of SLP-76 by p-SYK IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2730882 https://reactome.org/PathwayBrowser/#/R-RNO-2730882 Phosphorylation of PKC-theta IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2730884 https://reactome.org/PathwayBrowser/#/R-RNO-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-2730886 https://reactome.org/PathwayBrowser/#/R-RNO-2730886 Phosphorylation of SHC by SYK kinase IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-5690701 https://reactome.org/PathwayBrowser/#/R-RNO-5690701 SHP1 binds p-CD22 IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-5690702 https://reactome.org/PathwayBrowser/#/R-RNO-5690702 LYN phosphorylates CD22 IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-5690740 https://reactome.org/PathwayBrowser/#/R-RNO-5690740 CD22 binds B-cell receptor IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-8852266 https://reactome.org/PathwayBrowser/#/R-RNO-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-8852481 https://reactome.org/PathwayBrowser/#/R-RNO-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-8858428 https://reactome.org/PathwayBrowser/#/R-RNO-8858428 FCAMR binds IgA IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-9021306 https://reactome.org/PathwayBrowser/#/R-RNO-9021306 C1-Inh binds and inactivates C1r, C1s IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-9606151 https://reactome.org/PathwayBrowser/#/R-RNO-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-9724685 https://reactome.org/PathwayBrowser/#/R-RNO-9724685 IgE binds omalizumab IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-9725206 https://reactome.org/PathwayBrowser/#/R-RNO-9725206 IgE binds FCERI IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-983696 https://reactome.org/PathwayBrowser/#/R-RNO-983696 The Immunoglobulin of the BCR binds antigen IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-983700 https://reactome.org/PathwayBrowser/#/R-RNO-983700 SYK binds the activated BCR IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-983703 https://reactome.org/PathwayBrowser/#/R-RNO-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Rattus norvegicus A0A0G2K9Z5 R-RNO-983707 https://reactome.org/PathwayBrowser/#/R-RNO-983707 SYK autophosphorylates at the activated BCR IEA Rattus norvegicus A0A0G2KA07 R-RNO-6805546 https://reactome.org/PathwayBrowser/#/R-RNO-6805546 Keratin type I binds keratin type II IEA Rattus norvegicus A0A0G2KA07 R-RNO-6805573 https://reactome.org/PathwayBrowser/#/R-RNO-6805573 Keratin type I/type II heterodimers form tetramers IEA Rattus norvegicus A0A0G2KA07 R-RNO-6806610 https://reactome.org/PathwayBrowser/#/R-RNO-6806610 Keratin filament formation IEA Rattus norvegicus A0A0G2KA07 R-RNO-6806613 https://reactome.org/PathwayBrowser/#/R-RNO-6806613 Keratin tetramers bind to form unit length filaments IEA Rattus norvegicus A0A0G2KA07 R-RNO-6806629 https://reactome.org/PathwayBrowser/#/R-RNO-6806629 Formation of tonofilament bundles IEA Rattus norvegicus A0A0G2KA07 R-RNO-6809393 https://reactome.org/PathwayBrowser/#/R-RNO-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Rattus norvegicus A0A0G2KA07 R-RNO-6809663 https://reactome.org/PathwayBrowser/#/R-RNO-6809663 Formation of hair keratin fibres IEA Rattus norvegicus A0A0G2KA07 R-RNO-6810357 https://reactome.org/PathwayBrowser/#/R-RNO-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Rattus norvegicus A0A0G2KA07 R-RNO-6810937 https://reactome.org/PathwayBrowser/#/R-RNO-6810937 Lamellar bodies bind the early cornified envelope IEA Rattus norvegicus A0A0G2KA07 R-RNO-6814387 https://reactome.org/PathwayBrowser/#/R-RNO-6814387 CASP14 cleaves filaggrin IEA Rattus norvegicus A0A0G2KA07 R-RNO-6814734 https://reactome.org/PathwayBrowser/#/R-RNO-6814734 CDSN binds the cornified envelope IEA Rattus norvegicus A0A0G2KA07 R-RNO-6814764 https://reactome.org/PathwayBrowser/#/R-RNO-6814764 Plasma membrane resorption IEA Rattus norvegicus A0A0G2KA08 R-RNO-72180 https://reactome.org/PathwayBrowser/#/R-RNO-72180 Cleavage of mRNA at the 3'-end IEA Rattus norvegicus A0A0G2KA08 R-RNO-72185 https://reactome.org/PathwayBrowser/#/R-RNO-72185 mRNA polyadenylation IEA Rattus norvegicus A0A0G2KA08 R-RNO-72231 https://reactome.org/PathwayBrowser/#/R-RNO-72231 Formation of the Cleavage and Polyadenylation Complex IEA Rattus norvegicus A0A0G2KA08 R-RNO-77589 https://reactome.org/PathwayBrowser/#/R-RNO-77589 Recognition of AAUAAA sequence by CPSF IEA Rattus norvegicus A0A0G2KA08 R-RNO-77590 https://reactome.org/PathwayBrowser/#/R-RNO-77590 Recruitment of CstF to the CPSF Bound Pre-mRNA IEA Rattus norvegicus A0A0G2KA08 R-RNO-77591 https://reactome.org/PathwayBrowser/#/R-RNO-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Rattus norvegicus A0A0G2KA08 R-RNO-77592 https://reactome.org/PathwayBrowser/#/R-RNO-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Rattus norvegicus A0A0G2KA08 R-RNO-77593 https://reactome.org/PathwayBrowser/#/R-RNO-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Rattus norvegicus A0A0G2KA08 R-RNO-77594 https://reactome.org/PathwayBrowser/#/R-RNO-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Rattus norvegicus A0A0G2KA11 R-RNO-8850961 https://reactome.org/PathwayBrowser/#/R-RNO-8850961 PREX2 binds PTEN and inhibits it IEA Rattus norvegicus A0A0G2KA11 R-RNO-8980691 https://reactome.org/PathwayBrowser/#/R-RNO-8980691 RHOA GEFs activate RHOA IEA Rattus norvegicus A0A0G2KA11 R-RNO-9013143 https://reactome.org/PathwayBrowser/#/R-RNO-9013143 RAC1 GEFs activate RAC1 IEA Rattus norvegicus A0A0G2KA11 R-RNO-9013159 https://reactome.org/PathwayBrowser/#/R-RNO-9013159 CDC42 GEFs activate CDC42 IEA Rattus norvegicus A0A0G2KA84 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2KA84 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus A0A0G2KA84 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2KA84 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2KA90 R-RNO-6800426 https://reactome.org/PathwayBrowser/#/R-RNO-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Rattus norvegicus A0A0G2KA90 R-RNO-6809393 https://reactome.org/PathwayBrowser/#/R-RNO-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Rattus norvegicus A0A0G2KA90 R-RNO-6810357 https://reactome.org/PathwayBrowser/#/R-RNO-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Rattus norvegicus A0A0G2KA90 R-RNO-6810937 https://reactome.org/PathwayBrowser/#/R-RNO-6810937 Lamellar bodies bind the early cornified envelope IEA Rattus norvegicus A0A0G2KA90 R-RNO-6814387 https://reactome.org/PathwayBrowser/#/R-RNO-6814387 CASP14 cleaves filaggrin IEA Rattus norvegicus A0A0G2KA90 R-RNO-6814695 https://reactome.org/PathwayBrowser/#/R-RNO-6814695 PERP binds desmosomes IEA Rattus norvegicus A0A0G2KA90 R-RNO-6814734 https://reactome.org/PathwayBrowser/#/R-RNO-6814734 CDSN binds the cornified envelope IEA Rattus norvegicus A0A0G2KA90 R-RNO-6814764 https://reactome.org/PathwayBrowser/#/R-RNO-6814764 Plasma membrane resorption IEA Rattus norvegicus A0A0G2KAC6 R-RNO-6809663 https://reactome.org/PathwayBrowser/#/R-RNO-6809663 Formation of hair keratin fibres IEA Rattus norvegicus A0A0G2KAE1 R-RNO-446391 https://reactome.org/PathwayBrowser/#/R-RNO-446391 Formation of the PINCH-ILK-parvin complex IEA Rattus norvegicus A0A0G2KAE6 R-RNO-8954398 https://reactome.org/PathwayBrowser/#/R-RNO-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Rattus norvegicus A0A0G2KAH7 R-RNO-2022851 https://reactome.org/PathwayBrowser/#/R-RNO-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Rattus norvegicus A0A0G2KAH7 R-RNO-2022856 https://reactome.org/PathwayBrowser/#/R-RNO-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Rattus norvegicus A0A0G2KAH7 R-RNO-2022919 https://reactome.org/PathwayBrowser/#/R-RNO-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Rattus norvegicus A0A0G2KAH7 R-RNO-2076392 https://reactome.org/PathwayBrowser/#/R-RNO-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Rattus norvegicus A0A0G2KAI3 R-RNO-211966 https://reactome.org/PathwayBrowser/#/R-RNO-211966 CYP2D6 4-hydroxylates debrisoquine IEA Rattus norvegicus A0A0G2KAI3 R-RNO-211968 https://reactome.org/PathwayBrowser/#/R-RNO-211968 CYP2W1 oxidises INDOL IEA Rattus norvegicus A0A0G2KAI3 R-RNO-76456 https://reactome.org/PathwayBrowser/#/R-RNO-76456 O-atom dealkylation of dextromethorphan IEA Rattus norvegicus A0A0G2KAI8 R-RNO-9629578 https://reactome.org/PathwayBrowser/#/R-RNO-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Rattus norvegicus A0A0G2KAS0 R-RNO-8848658 https://reactome.org/PathwayBrowser/#/R-RNO-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Rattus norvegicus A0A0G2KAT2 R-RNO-8864278 https://reactome.org/PathwayBrowser/#/R-RNO-8864278 AP-2 (TFAP2) transcription factors form homo- and heterodimers IEA Rattus norvegicus A0A0G2KAT2 R-RNO-8864307 https://reactome.org/PathwayBrowser/#/R-RNO-8864307 TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP IEA Rattus norvegicus A0A0G2KAT2 R-RNO-8864343 https://reactome.org/PathwayBrowser/#/R-RNO-8864343 KCTD1 binds TFAP2 homo- and heterodimers IEA Rattus norvegicus A0A0G2KAT2 R-RNO-8864595 https://reactome.org/PathwayBrowser/#/R-RNO-8864595 TFAP2B homodimer binds YEATS4 IEA Rattus norvegicus A0A0G2KAT2 R-RNO-9836275 https://reactome.org/PathwayBrowser/#/R-RNO-9836275 TFAP2A binds TFAP2B IEA Rattus norvegicus A0A0G2KAU4 R-RNO-1168636 https://reactome.org/PathwayBrowser/#/R-RNO-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Rattus norvegicus A0A0G2KAU4 R-RNO-5672965 https://reactome.org/PathwayBrowser/#/R-RNO-5672965 RAS GEFs promote RAS nucleotide exchange IEA Rattus norvegicus A0A0G2KAU5 R-RNO-196840 https://reactome.org/PathwayBrowser/#/R-RNO-196840 3xPPCDC:3FMN decarboxylates PPC IEA Rattus norvegicus A0A0G2KB11 R-RNO-8873834 https://reactome.org/PathwayBrowser/#/R-RNO-8873834 STARD10 transports PC from ER membrane to lamellar body membrane IEA Rattus norvegicus A0A0G2KB11 R-RNO-8873923 https://reactome.org/PathwayBrowser/#/R-RNO-8873923 STARD10 binds LPCAT1 and PC IEA Rattus norvegicus A0A0G2KB11 R-RNO-8873929 https://reactome.org/PathwayBrowser/#/R-RNO-8873929 Casein kinase II phosphorylates STARD10 IEA Rattus norvegicus A0A0G2KB30 R-RNO-8952618 https://reactome.org/PathwayBrowser/#/R-RNO-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2KB30 R-RNO-8952620 https://reactome.org/PathwayBrowser/#/R-RNO-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2KB30 R-RNO-8955241 https://reactome.org/PathwayBrowser/#/R-RNO-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Rattus norvegicus A0A0G2KB30 R-RNO-8955289 https://reactome.org/PathwayBrowser/#/R-RNO-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Rattus norvegicus A0A0G2KB30 R-RNO-8956040 https://reactome.org/PathwayBrowser/#/R-RNO-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Rattus norvegicus A0A0G2KB30 R-RNO-8956200 https://reactome.org/PathwayBrowser/#/R-RNO-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A0G2KB30 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2KB30 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus A0A0G2KB30 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2KB30 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2KB38 R-RNO-5635854 https://reactome.org/PathwayBrowser/#/R-RNO-5635854 GLI2,3 are degraded by the proteasome IEA Rattus norvegicus A0A0G2KB38 R-RNO-5635855 https://reactome.org/PathwayBrowser/#/R-RNO-5635855 phosphorylated GLI proteins bind SPOP:CUL3:RBX1 IEA Rattus norvegicus A0A0G2KB38 R-RNO-5635856 https://reactome.org/PathwayBrowser/#/R-RNO-5635856 SPOP:CUL3:RBX1 ubiquitinates GLI2,3 IEA Rattus norvegicus A0A0G2KB87 R-RNO-9665067 https://reactome.org/PathwayBrowser/#/R-RNO-9665067 MET channel transports cations from the extracellular region into the cytosol of stereocilia TAS Rattus norvegicus A0A0G2KBC9 R-RNO-6798743 https://reactome.org/PathwayBrowser/#/R-RNO-6798743 Exocytosis of secretory granule membrane proteins IEA Rattus norvegicus A0A0G2KBC9 R-RNO-6798747 https://reactome.org/PathwayBrowser/#/R-RNO-6798747 Exocytosis of tertiary granule membrane proteins IEA Rattus norvegicus A0A0G2KBC9 R-RNO-6799350 https://reactome.org/PathwayBrowser/#/R-RNO-6799350 Exocytosis of specific granule membrane proteins IEA Rattus norvegicus A0A0G2KBC9 R-RNO-6800426 https://reactome.org/PathwayBrowser/#/R-RNO-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Rattus norvegicus A0A0G2KBD6 R-XTR-2574840 https://reactome.org/PathwayBrowser/#/R-XTR-2574840 AJUBA facilitates AURKA autophosphorylation IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-2574845 https://reactome.org/PathwayBrowser/#/R-XTR-2574845 AJUBA binds centrosome-associated AURKA IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-3000310 https://reactome.org/PathwayBrowser/#/R-XTR-3000310 AURKA phosphorylates PLK1 IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-3000319 https://reactome.org/PathwayBrowser/#/R-XTR-3000319 BORA binds PLK1 and AURKA IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-3772435 https://reactome.org/PathwayBrowser/#/R-XTR-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-380272 https://reactome.org/PathwayBrowser/#/R-XTR-380272 Plk1-mediated phosphorylation of Nlp IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-380283 https://reactome.org/PathwayBrowser/#/R-XTR-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-380303 https://reactome.org/PathwayBrowser/#/R-XTR-380303 Dissociation of Phospho-Nlp from the centrosome IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-380311 https://reactome.org/PathwayBrowser/#/R-XTR-380311 Recruitment of Plk1 to centrosomes IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-380316 https://reactome.org/PathwayBrowser/#/R-XTR-380316 Association of NuMA with microtubules IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-380455 https://reactome.org/PathwayBrowser/#/R-XTR-380455 Recruitment of CDK11p58 to the centrosomes IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-380508 https://reactome.org/PathwayBrowser/#/R-XTR-380508 Translocation of NuMA to the centrosomes IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-5617816 https://reactome.org/PathwayBrowser/#/R-XTR-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-5626220 https://reactome.org/PathwayBrowser/#/R-XTR-5626220 C2CD3 binds the mother centriole IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-5626227 https://reactome.org/PathwayBrowser/#/R-XTR-5626227 CP110 and CEP97 dissociate from the centriole IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-5626228 https://reactome.org/PathwayBrowser/#/R-XTR-5626228 The distal appendage proteins recruit TTBK2 IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-5638009 https://reactome.org/PathwayBrowser/#/R-XTR-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-8853405 https://reactome.org/PathwayBrowser/#/R-XTR-8853405 TPX2 binds AURKA at centrosomes IEA Xenopus tropicalis A0A0G2KBD6 R-XTR-8853419 https://reactome.org/PathwayBrowser/#/R-XTR-8853419 TPX2 promotes AURKA autophosphorylation IEA Xenopus tropicalis A0A0G2KDJ5 R-DRE-2424252 https://reactome.org/PathwayBrowser/#/R-DRE-2424252 COMP binds collagen, fibronectin, aggrecan and matrilins IEA Danio rerio A0A0G2KDJ5 R-DRE-2426259 https://reactome.org/PathwayBrowser/#/R-DRE-2426259 COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 IEA Danio rerio A0A0G2KQY6 R-DRE-442317 https://reactome.org/PathwayBrowser/#/R-DRE-442317 ZIP6 and ZIP14 mediate zinc influx into cells IEA Danio rerio A0A0G2KTI4 R-DRE-426086 https://reactome.org/PathwayBrowser/#/R-DRE-426086 SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol IEA Danio rerio A0A0G2L0J2 R-DRE-6801342 https://reactome.org/PathwayBrowser/#/R-DRE-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Danio rerio A0A0G2L7I0 R-DRE-5654985 https://reactome.org/PathwayBrowser/#/R-DRE-5654985 SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH IEA Danio rerio A0A0G2L7I0 R-DRE-5654986 https://reactome.org/PathwayBrowser/#/R-DRE-5654986 SPRTN binds monoUb:K164-PCNA associated with POLH IEA Danio rerio A0A0G2L7I0 R-DRE-5654989 https://reactome.org/PathwayBrowser/#/R-DRE-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Danio rerio A0A0G2QC02 R-RNO-430028 https://reactome.org/PathwayBrowser/#/R-RNO-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Rattus norvegicus A0A0G2QC09 R-RNO-9622571 https://reactome.org/PathwayBrowser/#/R-RNO-9622571 rNF-Y and Crebbp/Ep300 constitutively bind Bim gene promoter TAS Rattus norvegicus A0A0G2QC09 R-RNO-9622586 https://reactome.org/PathwayBrowser/#/R-RNO-9622586 Foxo1,Foxo3 bind Bcl2l11 gene promoter TAS Rattus norvegicus A0A0G2QC09 R-RNO-9622598 https://reactome.org/PathwayBrowser/#/R-RNO-9622598 Bcl2l11 gene expression is stimulated by Foxo1,Foxo3 and NF-Y TAS Rattus norvegicus A0A0G2QC27 R-RNO-6791221 https://reactome.org/PathwayBrowser/#/R-RNO-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA IEA Rattus norvegicus A0A0G2QC27 R-RNO-6791222 https://reactome.org/PathwayBrowser/#/R-RNO-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Rattus norvegicus A0A0G2QC27 R-RNO-6791227 https://reactome.org/PathwayBrowser/#/R-RNO-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Rattus norvegicus A0A0G2QC33 R-RNO-5681987 https://reactome.org/PathwayBrowser/#/R-RNO-5681987 LC3 is cleaved by ATG4 IEA Rattus norvegicus A0A0G2QC33 R-RNO-5682377 https://reactome.org/PathwayBrowser/#/R-RNO-5682377 LC3 de-lipidation by ATG4 IEA Rattus norvegicus A0A0G2QC37 R-RNO-429860 https://reactome.org/PathwayBrowser/#/R-RNO-429860 DCP1-DCP2 complex decaps mRNA IEA Rattus norvegicus A0A0G2QC37 R-RNO-450422 https://reactome.org/PathwayBrowser/#/R-RNO-450422 KSRP recruits RNA degradation activities IEA Rattus norvegicus A0A0G2QC37 R-RNO-450431 https://reactome.org/PathwayBrowser/#/R-RNO-450431 ZFP36 (TTP) recruits RNA degradation activities IEA Rattus norvegicus A0A0G2QC37 R-RNO-450488 https://reactome.org/PathwayBrowser/#/R-RNO-450488 BRF1 Complex recruits RNA degradation activities IEA Rattus norvegicus A0A0G2QC38 R-RNO-159101 https://reactome.org/PathwayBrowser/#/R-RNO-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Rattus norvegicus A0A0G2QC38 R-RNO-72103 https://reactome.org/PathwayBrowser/#/R-RNO-72103 Formation of pre-mRNPs IEA Rattus norvegicus A0A0G2QC38 R-RNO-72180 https://reactome.org/PathwayBrowser/#/R-RNO-72180 Cleavage of mRNA at the 3'-end IEA Rattus norvegicus A0A0G2QC38 R-RNO-72185 https://reactome.org/PathwayBrowser/#/R-RNO-72185 mRNA polyadenylation IEA Rattus norvegicus A0A0G2QC38 R-RNO-9770119 https://reactome.org/PathwayBrowser/#/R-RNO-9770119 Formation of the Spliceosomal E complex IEA Rattus norvegicus A0A0G2QC38 R-RNO-9770141 https://reactome.org/PathwayBrowser/#/R-RNO-9770141 Formation of the Spliceosomal C* complex IEA Rattus norvegicus A0A0G2QC38 R-RNO-9770142 https://reactome.org/PathwayBrowser/#/R-RNO-9770142 Formation of the Spliceosomal B complex IEA Rattus norvegicus A0A0G2QC38 R-RNO-9770236 https://reactome.org/PathwayBrowser/#/R-RNO-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Rattus norvegicus A0A0G2QC38 R-RNO-9794542 https://reactome.org/PathwayBrowser/#/R-RNO-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Rattus norvegicus A0A0G2QC40 R-RNO-8948757 https://reactome.org/PathwayBrowser/#/R-RNO-8948757 AKT phosphorylates MKRN1 IEA Rattus norvegicus A0A0G2QC40 R-RNO-8948775 https://reactome.org/PathwayBrowser/#/R-RNO-8948775 MKRN1 polyubiquitinates PTEN IEA Rattus norvegicus A0A0G2QC40 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A0G2QC40 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus A0A0G2QC40 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A0G2QC40 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A0G2QC64 R-RNO-5624949 https://reactome.org/PathwayBrowser/#/R-RNO-5624949 Assembly of the anterograde IFT train IEA Rattus norvegicus A0A0G2QC64 R-RNO-5624952 https://reactome.org/PathwayBrowser/#/R-RNO-5624952 Assembly of the retrograde IFT train IEA Rattus norvegicus A0A0G2QC64 R-RNO-5625416 https://reactome.org/PathwayBrowser/#/R-RNO-5625416 Anterograde IFT IEA Rattus norvegicus A0A0G2QC64 R-RNO-5625421 https://reactome.org/PathwayBrowser/#/R-RNO-5625421 The anterograde IFT train dissociates IEA Rattus norvegicus A0A0G2QC64 R-RNO-5625424 https://reactome.org/PathwayBrowser/#/R-RNO-5625424 The retrograde IFT train dissociates IEA Rattus norvegicus A0A0G2QC64 R-RNO-5625426 https://reactome.org/PathwayBrowser/#/R-RNO-5625426 Retrograde IFT IEA Rattus norvegicus A0A0H3UK16 R-DRE-170846 https://reactome.org/PathwayBrowser/#/R-DRE-170846 TGFBR2 recruits TGFBR1 IEA Danio rerio A0A0H3UK16 R-DRE-170861 https://reactome.org/PathwayBrowser/#/R-DRE-170861 Dimeric TGF-beta-1 binds to the receptor IEA Danio rerio A0A0H3UK16 R-DRE-190245 https://reactome.org/PathwayBrowser/#/R-DRE-190245 FGFR1b binds to FGF IEA Danio rerio A0A0H3UK16 R-DRE-190256 https://reactome.org/PathwayBrowser/#/R-DRE-190256 FGFR1c binds to FGF IEA Danio rerio A0A0H3UK16 R-DRE-9839358 https://reactome.org/PathwayBrowser/#/R-DRE-9839358 Endocytosis of TGFBR3:ARRB complex IEA Danio rerio A0A0H3UK16 R-DRE-9839363 https://reactome.org/PathwayBrowser/#/R-DRE-9839363 TGFBR3 phosphorylation by TGFBR2 complex IEA Danio rerio A0A0H3UK16 R-DRE-9839367 https://reactome.org/PathwayBrowser/#/R-DRE-9839367 TGFBR3_mem cleavage by MMPs IEA Danio rerio A0A0H3UK16 R-DRE-9839368 https://reactome.org/PathwayBrowser/#/R-DRE-9839368 TGFBR3(1-783) binds to TGFB1,TGFB2 IEA Danio rerio A0A0H3UK16 R-DRE-9839376 https://reactome.org/PathwayBrowser/#/R-DRE-9839376 TGFBR3(784-851) degradation IEA Danio rerio A0A0H3UK16 R-DRE-9839377 https://reactome.org/PathwayBrowser/#/R-DRE-9839377 TGFB1,TGFB2 bind TGFBR3 IEA Danio rerio A0A0H3UK16 R-DRE-9839378 https://reactome.org/PathwayBrowser/#/R-DRE-9839378 TGFBR3 binding to ARRB1/2 IEA Danio rerio A0A0H3UK16 R-DRE-9839379 https://reactome.org/PathwayBrowser/#/R-DRE-9839379 TGFBR3 binding to FGF2 IEA Danio rerio A0A0H3UK16 R-DRE-9839381 https://reactome.org/PathwayBrowser/#/R-DRE-9839381 FGF2:TGFBR3 binding to GIPC1 IEA Danio rerio A0A0H3UK16 R-DRE-9839388 https://reactome.org/PathwayBrowser/#/R-DRE-9839388 TGFBR3 translocation to plasma membrane IEA Danio rerio A0A0H3UK16 R-DRE-9839390 https://reactome.org/PathwayBrowser/#/R-DRE-9839390 TGFBR3 complex binds to TGFBR2 IEA Danio rerio A0A0H3UK16 R-DRE-9839401 https://reactome.org/PathwayBrowser/#/R-DRE-9839401 TGFBR3 degradation IEA Danio rerio A0A0H3UK16 R-DRE-9839402 https://reactome.org/PathwayBrowser/#/R-DRE-9839402 TGFBR3 binding to GIPC1 IEA Danio rerio A0A0H4J9E9 R-SSC-4641205 https://reactome.org/PathwayBrowser/#/R-SSC-4641205 RSPO:LGR binds ZNRF3 IEA Sus scrofa A0A0H4J9E9 R-SSC-4641206 https://reactome.org/PathwayBrowser/#/R-SSC-4641206 RSPOs bind LGRs IEA Sus scrofa A0A0H4J9E9 R-SSC-4641246 https://reactome.org/PathwayBrowser/#/R-SSC-4641246 ZNRF3 autoubiquitinates to promote its internalization IEA Sus scrofa A0A0H4LGZ0 R-DRE-1236940 https://reactome.org/PathwayBrowser/#/R-DRE-1236940 Exogenous soluble antigen targeted to more stable early endosome IEA Danio rerio A0A0H4LGZ0 R-DRE-1236941 https://reactome.org/PathwayBrowser/#/R-DRE-1236941 Internalization of receptor bound antigen into clathrin coted vesicles IEA Danio rerio A0A0H4LGZ0 R-DRE-1236955 https://reactome.org/PathwayBrowser/#/R-DRE-1236955 Movement of clathrin coated vesicles into early endosome IEA Danio rerio A0A0H5ANC0 R-SSC-2025723 https://reactome.org/PathwayBrowser/#/R-SSC-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Sus scrofa A0A0H5ANC0 R-SSC-2025724 https://reactome.org/PathwayBrowser/#/R-SSC-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Sus scrofa A0A0H5ANC0 R-SSC-2046175 https://reactome.org/PathwayBrowser/#/R-SSC-2046175 Further sulfation on galactose residues produces KSPG IEA Sus scrofa A0A0H5ANC0 R-SSC-2046180 https://reactome.org/PathwayBrowser/#/R-SSC-2046180 KSPG is secreted from the cell IEA Sus scrofa A0A0H5ANC0 R-SSC-2046222 https://reactome.org/PathwayBrowser/#/R-SSC-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Sus scrofa A0A0H5ANC0 R-SSC-2046239 https://reactome.org/PathwayBrowser/#/R-SSC-2046239 Extracellular KSPG translocates to the lysosome for degradation IEA Sus scrofa A0A0H5ANC0 R-SSC-2046265 https://reactome.org/PathwayBrowser/#/R-SSC-2046265 B4GALTs transfer Gal to the keratan chain IEA Sus scrofa A0A0H5ANC0 R-SSC-2046285 https://reactome.org/PathwayBrowser/#/R-SSC-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Sus scrofa A0A0H5ANC0 R-SSC-2046298 https://reactome.org/PathwayBrowser/#/R-SSC-2046298 B4GALTs transfer Gal to a branch of keratan IEA Sus scrofa A0A0H5AX08 R-SSC-5607732 https://reactome.org/PathwayBrowser/#/R-SSC-5607732 K63polyUb-TAK1 autophosphorylates IEA Sus scrofa A0A0H5AX08 R-SSC-5607733 https://reactome.org/PathwayBrowser/#/R-SSC-5607733 BCL10 binds CARD9 IEA Sus scrofa A0A0H5AX08 R-SSC-5607736 https://reactome.org/PathwayBrowser/#/R-SSC-5607736 MALT1 oligomerizes IEA Sus scrofa A0A0H5AX08 R-SSC-5607737 https://reactome.org/PathwayBrowser/#/R-SSC-5607737 BCL10 oligomerizes IEA Sus scrofa A0A0H5AX08 R-SSC-5607740 https://reactome.org/PathwayBrowser/#/R-SSC-5607740 PKC-delta phosphorylates CARD9 IEA Sus scrofa A0A0H5AX08 R-SSC-5607742 https://reactome.org/PathwayBrowser/#/R-SSC-5607742 K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta IEA Sus scrofa A0A0H5AX08 R-SSC-5607744 https://reactome.org/PathwayBrowser/#/R-SSC-5607744 MALT1 binds BCL10 IEA Sus scrofa A0A0H5AX08 R-SSC-5607747 https://reactome.org/PathwayBrowser/#/R-SSC-5607747 TRAF6 binds MALT1 oligomers IEA Sus scrofa A0A0H5AX08 R-SSC-5607751 https://reactome.org/PathwayBrowser/#/R-SSC-5607751 TRAF6 oligomerizes IEA Sus scrofa A0A0H5AX08 R-SSC-5607753 https://reactome.org/PathwayBrowser/#/R-SSC-5607753 CARD9 oligomerizes IEA Sus scrofa A0A0H5AX08 R-SSC-5607756 https://reactome.org/PathwayBrowser/#/R-SSC-5607756 TRAF6 oligomer autoubiquitinates IEA Sus scrofa A0A0H5AX08 R-SSC-5607757 https://reactome.org/PathwayBrowser/#/R-SSC-5607757 K63polyUb-TRAF6 ubiquitinates TAK1 IEA Sus scrofa A0A0H5AX08 R-SSC-5607759 https://reactome.org/PathwayBrowser/#/R-SSC-5607759 TRIKA2 binds K63polyUb-TRAF6 oligomer IEA Sus scrofa A0A0J9YU71 R-MMU-975040 https://reactome.org/PathwayBrowser/#/R-MMU-975040 KRAB-ZNF / KAP Interaction IEA Mus musculus A0A0J9YUD4 R-MMU-975040 https://reactome.org/PathwayBrowser/#/R-MMU-975040 KRAB-ZNF / KAP Interaction IEA Mus musculus A0A0J9YUD4 R-MMU-9842833 https://reactome.org/PathwayBrowser/#/R-MMU-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Mus musculus A0A0J9YUD5 R-MMU-111439 https://reactome.org/PathwayBrowser/#/R-MMU-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Mus musculus A0A0J9YUD5 R-MMU-158441 https://reactome.org/PathwayBrowser/#/R-MMU-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Mus musculus A0A0J9YUD5 R-MMU-158447 https://reactome.org/PathwayBrowser/#/R-MMU-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Mus musculus A0A0J9YUD5 R-MMU-158481 https://reactome.org/PathwayBrowser/#/R-MMU-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Mus musculus A0A0J9YUD5 R-MMU-158484 https://reactome.org/PathwayBrowser/#/R-MMU-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Mus musculus A0A0J9YUD5 R-MMU-159046 https://reactome.org/PathwayBrowser/#/R-MMU-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Mus musculus A0A0J9YUD5 R-MMU-159050 https://reactome.org/PathwayBrowser/#/R-MMU-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Mus musculus A0A0J9YUD5 R-MMU-170796 https://reactome.org/PathwayBrowser/#/R-MMU-170796 NPC transports GCK1:GKRP from cytosol to nucleoplasm IEA Mus musculus A0A0J9YUD5 R-MMU-170825 https://reactome.org/PathwayBrowser/#/R-MMU-170825 NPC exports GCK1 from nucleus IEA Mus musculus A0A0J9YUD5 R-MMU-191830 https://reactome.org/PathwayBrowser/#/R-MMU-191830 snRNP nuclear import and release IEA Mus musculus A0A0J9YUD5 R-MMU-2990882 https://reactome.org/PathwayBrowser/#/R-MMU-2990882 CDK1 phosphorylates NUP98 IEA Mus musculus A0A0J9YUD5 R-MMU-3000348 https://reactome.org/PathwayBrowser/#/R-MMU-3000348 RANBP2 SUMOylates SP100 with SUMO2 IEA Mus musculus A0A0J9YUD5 R-MMU-3000399 https://reactome.org/PathwayBrowser/#/R-MMU-3000399 RANBP2 SUMOylates SP100 with SUMO1 IEA Mus musculus A0A0J9YUD5 R-MMU-3000411 https://reactome.org/PathwayBrowser/#/R-MMU-3000411 RANBP2 SUMOylates PML with SUMO2 IEA Mus musculus A0A0J9YUD5 R-MMU-4551649 https://reactome.org/PathwayBrowser/#/R-MMU-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Mus musculus A0A0J9YUD5 R-MMU-4551679 https://reactome.org/PathwayBrowser/#/R-MMU-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Mus musculus A0A0J9YUD5 R-MMU-4570493 https://reactome.org/PathwayBrowser/#/R-MMU-4570493 RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 IEA Mus musculus A0A0J9YUD5 R-MMU-4615872 https://reactome.org/PathwayBrowser/#/R-MMU-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Mus musculus A0A0J9YUD5 R-MMU-4615987 https://reactome.org/PathwayBrowser/#/R-MMU-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Mus musculus A0A0J9YUD5 R-MMU-4655355 https://reactome.org/PathwayBrowser/#/R-MMU-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Mus musculus A0A0J9YUD5 R-MMU-5228508 https://reactome.org/PathwayBrowser/#/R-MMU-5228508 RANBP2 SUMOylates PML with SUMO1 IEA Mus musculus A0A0J9YUD5 R-MMU-5228523 https://reactome.org/PathwayBrowser/#/R-MMU-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Mus musculus A0A0J9YUD5 R-MMU-5252041 https://reactome.org/PathwayBrowser/#/R-MMU-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Mus musculus A0A0J9YUD5 R-MMU-5578744 https://reactome.org/PathwayBrowser/#/R-MMU-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Mus musculus A0A0J9YUD5 R-MMU-75097 https://reactome.org/PathwayBrowser/#/R-MMU-75097 Transport of the export-competent mRNP complex through the NPC IEA Mus musculus A0A0J9YUD5 R-MMU-75098 https://reactome.org/PathwayBrowser/#/R-MMU-75098 mRNP complex dissociates from cytosolic face of NPC IEA Mus musculus A0A0J9YUD5 R-MMU-77587 https://reactome.org/PathwayBrowser/#/R-MMU-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Mus musculus A0A0J9YUD5 R-MMU-77594 https://reactome.org/PathwayBrowser/#/R-MMU-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Mus musculus A0A0J9YUD5 R-MMU-9634169 https://reactome.org/PathwayBrowser/#/R-MMU-9634169 POM121 and NDC1 bind the Nup93 complex IEA Mus musculus A0A0J9YUH2 R-MMU-1168638 https://reactome.org/PathwayBrowser/#/R-MMU-1168638 Activated IKK phosphorylates I-kappaB IEA Mus musculus A0A0J9YUH2 R-MMU-1168640 https://reactome.org/PathwayBrowser/#/R-MMU-1168640 Ubiquitinated IkB is degraded IEA Mus musculus A0A0J9YUH2 R-MMU-1168642 https://reactome.org/PathwayBrowser/#/R-MMU-1168642 SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB IEA Mus musculus A0A0J9YUH2 R-MMU-1168643 https://reactome.org/PathwayBrowser/#/R-MMU-1168643 SCF-beta-TrCP ubiquitinylates IkB IEA Mus musculus A0A0J9YUW3 R-MMU-975040 https://reactome.org/PathwayBrowser/#/R-MMU-975040 KRAB-ZNF / KAP Interaction IEA Mus musculus A0A0J9YUW3 R-MMU-9842833 https://reactome.org/PathwayBrowser/#/R-MMU-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Mus musculus A0A0J9YUZ3 R-MMU-1168638 https://reactome.org/PathwayBrowser/#/R-MMU-1168638 Activated IKK phosphorylates I-kappaB IEA Mus musculus A0A0J9YUZ3 R-MMU-1168640 https://reactome.org/PathwayBrowser/#/R-MMU-1168640 Ubiquitinated IkB is degraded IEA Mus musculus A0A0J9YUZ3 R-MMU-1168642 https://reactome.org/PathwayBrowser/#/R-MMU-1168642 SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB IEA Mus musculus A0A0J9YUZ3 R-MMU-1168643 https://reactome.org/PathwayBrowser/#/R-MMU-1168643 SCF-beta-TrCP ubiquitinylates IkB IEA Mus musculus A0A0K0PUH6 R-GGA-481009 https://reactome.org/PathwayBrowser/#/R-GGA-481009 Exocytosis of platelet dense granule content IEA Gallus gallus A0A0K0WSQ7 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio A0A0K0WSQ7 R-DRE-388560 https://reactome.org/PathwayBrowser/#/R-DRE-388560 EDNRA,EDNRB bind EDNs IEA Danio rerio A0A0K0WSQ7 R-DRE-9731924 https://reactome.org/PathwayBrowser/#/R-DRE-9731924 EDNRA binds EDNs IEA Danio rerio A0A0K1TQQ0 R-SSC-176059 https://reactome.org/PathwayBrowser/#/R-SSC-176059 GST trimers transfer GS from GSH to luminal substrates IEA Sus scrofa A0A0K1TQQ0 R-SSC-5423653 https://reactome.org/PathwayBrowser/#/R-SSC-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO IEA Sus scrofa A0A0K3AQN0 R-CEL-205039 https://reactome.org/PathwayBrowser/#/R-CEL-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Caenorhabditis elegans A0A0K3AQN0 R-CEL-2160931 https://reactome.org/PathwayBrowser/#/R-CEL-2160931 Disassembly of tight junctions IEA Caenorhabditis elegans A0A0K3AQN0 R-CEL-3928592 https://reactome.org/PathwayBrowser/#/R-CEL-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Caenorhabditis elegans A0A0K3AQN0 R-CEL-3928598 https://reactome.org/PathwayBrowser/#/R-CEL-3928598 Recruitment of p190RhoGEF to p-FAK IEA Caenorhabditis elegans A0A0K3AQN0 R-CEL-419166 https://reactome.org/PathwayBrowser/#/R-CEL-419166 GEFs activate RhoA,B,C IEA Caenorhabditis elegans A0A0K3AQN0 R-CEL-8980691 https://reactome.org/PathwayBrowser/#/R-CEL-8980691 RHOA GEFs activate RHOA IEA Caenorhabditis elegans A0A0K3AQN0 R-CEL-9013023 https://reactome.org/PathwayBrowser/#/R-CEL-9013023 RHOB GEFs activate RHOB IEA Caenorhabditis elegans A0A0K3AQN0 R-CEL-9013143 https://reactome.org/PathwayBrowser/#/R-CEL-9013143 RAC1 GEFs activate RAC1 IEA Caenorhabditis elegans A0A0K3AQR5 R-CEL-8956040 https://reactome.org/PathwayBrowser/#/R-CEL-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Caenorhabditis elegans A0A0K3AQR5 R-CEL-8956045 https://reactome.org/PathwayBrowser/#/R-CEL-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Caenorhabditis elegans A0A0K3AQR5 R-CEL-8956103 https://reactome.org/PathwayBrowser/#/R-CEL-8956103 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha IEA Caenorhabditis elegans A0A0K3AQR5 R-CEL-8956106 https://reactome.org/PathwayBrowser/#/R-CEL-8956106 VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha IEA Caenorhabditis elegans A0A0K3AQR5 R-CEL-9755303 https://reactome.org/PathwayBrowser/#/R-CEL-9755303 26S proteasome degrades HIFalpha IEA Caenorhabditis elegans A0A0K3AR51 R-CEL-1011598 https://reactome.org/PathwayBrowser/#/R-CEL-1011598 DOCKs bind to RhoGEFs IEA Caenorhabditis elegans A0A0K3AR51 R-CEL-9013143 https://reactome.org/PathwayBrowser/#/R-CEL-9013143 RAC1 GEFs activate RAC1 IEA Caenorhabditis elegans A0A0K3AR51 R-CEL-9013159 https://reactome.org/PathwayBrowser/#/R-CEL-9013159 CDC42 GEFs activate CDC42 IEA Caenorhabditis elegans A0A0K3AR51 R-CEL-9014296 https://reactome.org/PathwayBrowser/#/R-CEL-9014296 RAC2 GEFs activate RAC2 IEA Caenorhabditis elegans A0A0K3AR51 R-CEL-9018804 https://reactome.org/PathwayBrowser/#/R-CEL-9018804 RAC3 GEFs activate RAC3 IEA Caenorhabditis elegans A0A0K3ARA3 R-CEL-9018758 https://reactome.org/PathwayBrowser/#/R-CEL-9018758 RHOH binds effectors at the plasma membrane IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-205039 https://reactome.org/PathwayBrowser/#/R-CEL-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-3928595 https://reactome.org/PathwayBrowser/#/R-CEL-3928595 N-WASP binds ARP2/3 and G-actin IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-3928601 https://reactome.org/PathwayBrowser/#/R-CEL-3928601 CDC42 and PIP2 bind WASL, activating it IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-419166 https://reactome.org/PathwayBrowser/#/R-CEL-419166 GEFs activate RhoA,B,C IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-8856813 https://reactome.org/PathwayBrowser/#/R-CEL-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-8866283 https://reactome.org/PathwayBrowser/#/R-CEL-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-8867756 https://reactome.org/PathwayBrowser/#/R-CEL-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-8868072 https://reactome.org/PathwayBrowser/#/R-CEL-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-8868236 https://reactome.org/PathwayBrowser/#/R-CEL-8868236 BAR domain proteins recruit dynamin IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-8868648 https://reactome.org/PathwayBrowser/#/R-CEL-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-8868651 https://reactome.org/PathwayBrowser/#/R-CEL-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-8868658 https://reactome.org/PathwayBrowser/#/R-CEL-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-8868659 https://reactome.org/PathwayBrowser/#/R-CEL-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-8868660 https://reactome.org/PathwayBrowser/#/R-CEL-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-8868661 https://reactome.org/PathwayBrowser/#/R-CEL-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-8871194 https://reactome.org/PathwayBrowser/#/R-CEL-8871194 RAB5 and GAPVD1 bind AP-2 IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-9013159 https://reactome.org/PathwayBrowser/#/R-CEL-9013159 CDC42 GEFs activate CDC42 IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-9014433 https://reactome.org/PathwayBrowser/#/R-CEL-9014433 RHOG GEFs activate RHOG IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-9018747 https://reactome.org/PathwayBrowser/#/R-CEL-9018747 RHOQ GEFs activate RHOQ IEA Caenorhabditis elegans A0A0K3AS36 R-CEL-9018766 https://reactome.org/PathwayBrowser/#/R-CEL-9018766 RHOU binds effectors at the plasma membrane IEA Caenorhabditis elegans A0A0K3AST9 R-CEL-6798739 https://reactome.org/PathwayBrowser/#/R-CEL-6798739 Exocytosis of azurophil granule membrane proteins IEA Caenorhabditis elegans A0A0K3AST9 R-CEL-6798745 https://reactome.org/PathwayBrowser/#/R-CEL-6798745 Exocytosis of tertiary granule lumen proteins IEA Caenorhabditis elegans A0A0K3AST9 R-CEL-6798749 https://reactome.org/PathwayBrowser/#/R-CEL-6798749 Exocytosis of specific granule lumen proteins IEA Caenorhabditis elegans A0A0K3AU54 R-CEL-9629888 https://reactome.org/PathwayBrowser/#/R-CEL-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Caenorhabditis elegans A0A0K3AUF6 R-CEL-1889955 https://reactome.org/PathwayBrowser/#/R-CEL-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Caenorhabditis elegans A0A0K3AUI7 R-CEL-4647594 https://reactome.org/PathwayBrowser/#/R-CEL-4647594 SAHF formation IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-1504186 https://reactome.org/PathwayBrowser/#/R-CEL-1504186 DVL recruits GSK3beta:AXIN1 to the receptor complex IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-1504190 https://reactome.org/PathwayBrowser/#/R-CEL-1504190 DVL is ubiquitinated by CUL3:KLHL12:RBX1 IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-201677 https://reactome.org/PathwayBrowser/#/R-CEL-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-201717 https://reactome.org/PathwayBrowser/#/R-CEL-201717 CSNK2-mediated phosphorylation of DVL IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-2066299 https://reactome.org/PathwayBrowser/#/R-CEL-2066299 DVL2 binds phosphorylated WWTR1 (TAZ) IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-3772434 https://reactome.org/PathwayBrowser/#/R-CEL-3772434 Phosphorylated DVL recruits PIP5K1B to the plasma membrane IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-3772435 https://reactome.org/PathwayBrowser/#/R-CEL-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-3772436 https://reactome.org/PathwayBrowser/#/R-CEL-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-3858475 https://reactome.org/PathwayBrowser/#/R-CEL-3858475 ppDVL recruits RAC IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-3858482 https://reactome.org/PathwayBrowser/#/R-CEL-3858482 DVL is recruited to the receptor IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-3858489 https://reactome.org/PathwayBrowser/#/R-CEL-3858489 ppDVL binds DAAM1 IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-3858495 https://reactome.org/PathwayBrowser/#/R-CEL-3858495 DAAM1 recruits GTP-bound RHOA IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-4641155 https://reactome.org/PathwayBrowser/#/R-CEL-4641155 DVL1 is bound by the HECT ubiquitin ligase HECW1 IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-4641159 https://reactome.org/PathwayBrowser/#/R-CEL-4641159 DVL1 is ubiquitinated by HECW1 IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-4641260 https://reactome.org/PathwayBrowser/#/R-CEL-4641260 Ubiquitinated DVL1 is degraded by the proteasome IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-5138432 https://reactome.org/PathwayBrowser/#/R-CEL-5138432 DVL2 is phosphorylated by PKC IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-5138433 https://reactome.org/PathwayBrowser/#/R-CEL-5138433 p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-5138441 https://reactome.org/PathwayBrowser/#/R-CEL-5138441 WNT5A-FZD4 recruits DVL2 IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-5138459 https://reactome.org/PathwayBrowser/#/R-CEL-5138459 WNT5A:FZD4 is endocytosed IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-8866269 https://reactome.org/PathwayBrowser/#/R-CEL-8866269 ARRB bind GPCRs IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-8866283 https://reactome.org/PathwayBrowser/#/R-CEL-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-8867756 https://reactome.org/PathwayBrowser/#/R-CEL-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-8868072 https://reactome.org/PathwayBrowser/#/R-CEL-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-8868236 https://reactome.org/PathwayBrowser/#/R-CEL-8868236 BAR domain proteins recruit dynamin IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-8868648 https://reactome.org/PathwayBrowser/#/R-CEL-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-8868651 https://reactome.org/PathwayBrowser/#/R-CEL-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-8868658 https://reactome.org/PathwayBrowser/#/R-CEL-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-8868659 https://reactome.org/PathwayBrowser/#/R-CEL-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-8868660 https://reactome.org/PathwayBrowser/#/R-CEL-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-8868661 https://reactome.org/PathwayBrowser/#/R-CEL-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Caenorhabditis elegans A0A0K3AUI8 R-CEL-8871194 https://reactome.org/PathwayBrowser/#/R-CEL-8871194 RAB5 and GAPVD1 bind AP-2 IEA Caenorhabditis elegans A0A0K3AUJ9 R-CEL-3341343 https://reactome.org/PathwayBrowser/#/R-CEL-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Caenorhabditis elegans A0A0K3AUJ9 R-CEL-5631885 https://reactome.org/PathwayBrowser/#/R-CEL-5631885 PRDX1 overoxidizes IEA Caenorhabditis elegans A0A0K3AUJ9 R-CEL-5631903 https://reactome.org/PathwayBrowser/#/R-CEL-5631903 SESN1,2,3 bind overoxidized PRDX1 IEA Caenorhabditis elegans A0A0K3AUS7 R-CEL-5655892 https://reactome.org/PathwayBrowser/#/R-CEL-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Caenorhabditis elegans A0A0K3AUS7 R-CEL-5656148 https://reactome.org/PathwayBrowser/#/R-CEL-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Caenorhabditis elegans A0A0K3AVC3 R-CEL-5693925 https://reactome.org/PathwayBrowser/#/R-CEL-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Caenorhabditis elegans A0A0K3AVC3 R-CEL-9603984 https://reactome.org/PathwayBrowser/#/R-CEL-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Caenorhabditis elegans A0A0K3AVC3 R-CEL-9603986 https://reactome.org/PathwayBrowser/#/R-CEL-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Caenorhabditis elegans A0A0K3AVC3 R-CEL-9605609 https://reactome.org/PathwayBrowser/#/R-CEL-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Caenorhabditis elegans A0A0K3AVC3 R-CEL-9605644 https://reactome.org/PathwayBrowser/#/R-CEL-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Caenorhabditis elegans A0A0K3AVC3 R-CEL-9605682 https://reactome.org/PathwayBrowser/#/R-CEL-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Caenorhabditis elegans A0A0K3AVS8 R-CEL-382096 https://reactome.org/PathwayBrowser/#/R-CEL-382096 Formation of NR-NCOR Corepressor Complex IEA Caenorhabditis elegans A0A0K3AVS8 R-CEL-5334854 https://reactome.org/PathwayBrowser/#/R-CEL-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Caenorhabditis elegans A0A0K3AVS8 R-CEL-5634103 https://reactome.org/PathwayBrowser/#/R-CEL-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Caenorhabditis elegans A0A0K3AVS8 R-CEL-9009817 https://reactome.org/PathwayBrowser/#/R-CEL-9009817 Acitretin binds to RAR:RXR IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-165026 https://reactome.org/PathwayBrowser/#/R-CEL-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-2161500 https://reactome.org/PathwayBrowser/#/R-CEL-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-374896 https://reactome.org/PathwayBrowser/#/R-CEL-374896 Uptake of Noradrenaline IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-374919 https://reactome.org/PathwayBrowser/#/R-CEL-374919 Noradrenaline clearance from the synaptic cleft IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-549241 https://reactome.org/PathwayBrowser/#/R-CEL-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-549297 https://reactome.org/PathwayBrowser/#/R-CEL-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-549304 https://reactome.org/PathwayBrowser/#/R-CEL-549304 OCT3 mediates renal clearance of organic cations IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-561041 https://reactome.org/PathwayBrowser/#/R-CEL-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-561059 https://reactome.org/PathwayBrowser/#/R-CEL-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-561072 https://reactome.org/PathwayBrowser/#/R-CEL-561072 OCT3 mediates renal uptake of organic cations IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-561253 https://reactome.org/PathwayBrowser/#/R-CEL-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-9749583 https://reactome.org/PathwayBrowser/#/R-CEL-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-9794523 https://reactome.org/PathwayBrowser/#/R-CEL-9794523 SLC22A1 transports Cipro into renal cell IEA Caenorhabditis elegans A0A0K3AVV4 R-CEL-9795207 https://reactome.org/PathwayBrowser/#/R-CEL-9795207 SLC22A1 transports Cipro into hepatic cell IEA Caenorhabditis elegans A0A0K3AW57 R-CEL-8981637 https://reactome.org/PathwayBrowser/#/R-CEL-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-165026 https://reactome.org/PathwayBrowser/#/R-CEL-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-2161500 https://reactome.org/PathwayBrowser/#/R-CEL-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-374896 https://reactome.org/PathwayBrowser/#/R-CEL-374896 Uptake of Noradrenaline IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-374919 https://reactome.org/PathwayBrowser/#/R-CEL-374919 Noradrenaline clearance from the synaptic cleft IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-549241 https://reactome.org/PathwayBrowser/#/R-CEL-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-549297 https://reactome.org/PathwayBrowser/#/R-CEL-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-549304 https://reactome.org/PathwayBrowser/#/R-CEL-549304 OCT3 mediates renal clearance of organic cations IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-561041 https://reactome.org/PathwayBrowser/#/R-CEL-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-561059 https://reactome.org/PathwayBrowser/#/R-CEL-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-561072 https://reactome.org/PathwayBrowser/#/R-CEL-561072 OCT3 mediates renal uptake of organic cations IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-561253 https://reactome.org/PathwayBrowser/#/R-CEL-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-9749583 https://reactome.org/PathwayBrowser/#/R-CEL-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-9794523 https://reactome.org/PathwayBrowser/#/R-CEL-9794523 SLC22A1 transports Cipro into renal cell IEA Caenorhabditis elegans A0A0K3AWD3 R-CEL-9795207 https://reactome.org/PathwayBrowser/#/R-CEL-9795207 SLC22A1 transports Cipro into hepatic cell IEA Caenorhabditis elegans A0A0K3AWM6 R-CEL-1504186 https://reactome.org/PathwayBrowser/#/R-CEL-1504186 DVL recruits GSK3beta:AXIN1 to the receptor complex IEA Caenorhabditis elegans A0A0K3AWM6 R-CEL-201677 https://reactome.org/PathwayBrowser/#/R-CEL-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Caenorhabditis elegans A0A0K3AWM6 R-CEL-3858482 https://reactome.org/PathwayBrowser/#/R-CEL-3858482 DVL is recruited to the receptor IEA Caenorhabditis elegans A0A0K3AWM6 R-CEL-3965444 https://reactome.org/PathwayBrowser/#/R-CEL-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Caenorhabditis elegans A0A0K3AWM6 R-CEL-3965447 https://reactome.org/PathwayBrowser/#/R-CEL-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Caenorhabditis elegans A0A0K3AWM6 R-CEL-4641253 https://reactome.org/PathwayBrowser/#/R-CEL-4641253 ZNRF3 ubiquitinates FZD to promote its downregulation IEA Caenorhabditis elegans A0A0K3AWM6 R-CEL-5099886 https://reactome.org/PathwayBrowser/#/R-CEL-5099886 WNT5A binding to FZD promotes PRICKLE1 degradation IEA Caenorhabditis elegans A0A0K3AWM6 R-CEL-5140741 https://reactome.org/PathwayBrowser/#/R-CEL-5140741 WNT5A binds FZD and ROR receptors IEA Caenorhabditis elegans A0A0K3AWM6 R-CEL-5140747 https://reactome.org/PathwayBrowser/#/R-CEL-5140747 FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner IEA Caenorhabditis elegans A0A0K3AXD3 R-CEL-167419 https://reactome.org/PathwayBrowser/#/R-CEL-167419 The receptor:G-protein complex releases GDP IEA Caenorhabditis elegans A0A0K3AXD3 R-CEL-167429 https://reactome.org/PathwayBrowser/#/R-CEL-167429 The receptor:G-protein complex binds GTP IEA Caenorhabditis elegans A0A0K3AXD3 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans A0A0K3AXD3 R-CEL-391934 https://reactome.org/PathwayBrowser/#/R-CEL-391934 DP2 receptor can bind PGD2 IEA Caenorhabditis elegans A0A0K3AXD3 R-CEL-5624126 https://reactome.org/PathwayBrowser/#/R-CEL-5624126 ARL6:GTP and the BBSome bind ciliary cargo IEA Caenorhabditis elegans A0A0K3AXD3 R-CEL-5624127 https://reactome.org/PathwayBrowser/#/R-CEL-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Caenorhabditis elegans A0A0K3AXD3 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans A0A0K3AXD3 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans A0A0K3AXD3 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans A0A0M3KL54 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A0M3KL54 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A0M3KL54 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A0M3KL54 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A0M3KL54 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A0M3KL55 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A0M3KL55 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A0M3KL55 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A0M3KL55 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A0M3KL55 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A0M3KL56 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A0M3KL56 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A0M3KL56 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A0M3KL56 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A0M3KL56 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A0M7REQ4 R-CEL-8932309 https://reactome.org/PathwayBrowser/#/R-CEL-8932309 NFE2L2 translocates from cytosol to nucleoplasm IEA Caenorhabditis elegans A0A0M7REQ4 R-CEL-8932355 https://reactome.org/PathwayBrowser/#/R-CEL-8932355 26S proteasome degrades Ub-NFE2L2 IEA Caenorhabditis elegans A0A0M7REQ4 R-CEL-9712274 https://reactome.org/PathwayBrowser/#/R-CEL-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Caenorhabditis elegans A0A0M7REQ4 R-CEL-9755505 https://reactome.org/PathwayBrowser/#/R-CEL-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Caenorhabditis elegans A0A0M7REQ4 R-CEL-9755507 https://reactome.org/PathwayBrowser/#/R-CEL-9755507 UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex IEA Caenorhabditis elegans A0A0M7REQ4 R-CEL-9760081 https://reactome.org/PathwayBrowser/#/R-CEL-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Caenorhabditis elegans A0A0M7REQ4 R-CEL-9760082 https://reactome.org/PathwayBrowser/#/R-CEL-9760082 NFE2L2 binds CREBBP,EP300 IEA Caenorhabditis elegans A0A0M7REQ4 R-CEL-9762091 https://reactome.org/PathwayBrowser/#/R-CEL-9762091 NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 IEA Caenorhabditis elegans A0A0M7REQ4 R-CEL-9762093 https://reactome.org/PathwayBrowser/#/R-CEL-9762093 BTRC binds p-S344, 347 NFE2L2 IEA Caenorhabditis elegans A0A0M7REQ4 R-CEL-9762094 https://reactome.org/PathwayBrowser/#/R-CEL-9762094 GSK3B phosphorylates p-NFE2L2 IEA Caenorhabditis elegans A0A0M7REQ4 R-CEL-9762096 https://reactome.org/PathwayBrowser/#/R-CEL-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Caenorhabditis elegans A0A0M7REQ4 R-CEL-9796047 https://reactome.org/PathwayBrowser/#/R-CEL-9796047 PRKAA2 regulated nuclear export of NFE2L2 IEA Caenorhabditis elegans A0A0M7REQ4 R-CEL-9796053 https://reactome.org/PathwayBrowser/#/R-CEL-9796053 PRKCI phosphorylates NFE2L2 IEA Caenorhabditis elegans A0A0M7REQ4 R-CEL-9796067 https://reactome.org/PathwayBrowser/#/R-CEL-9796067 PRKAA2 phosphorylates nuclear NFE2L2 IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-143468 https://reactome.org/PathwayBrowser/#/R-CEL-143468 MEOS oxidizes ethanol to acetaldehyde IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-156526 https://reactome.org/PathwayBrowser/#/R-CEL-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-211874 https://reactome.org/PathwayBrowser/#/R-CEL-211874 CYP2S1 4-hydroxylates atRA IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-211881 https://reactome.org/PathwayBrowser/#/R-CEL-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-211910 https://reactome.org/PathwayBrowser/#/R-CEL-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-211929 https://reactome.org/PathwayBrowser/#/R-CEL-211929 CYP2C19 5-hydroxylates omeprazole IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-211966 https://reactome.org/PathwayBrowser/#/R-CEL-211966 CYP2D6 4-hydroxylates debrisoquine IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-211968 https://reactome.org/PathwayBrowser/#/R-CEL-211968 CYP2W1 oxidises INDOL IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-211988 https://reactome.org/PathwayBrowser/#/R-CEL-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-211991 https://reactome.org/PathwayBrowser/#/R-CEL-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-212004 https://reactome.org/PathwayBrowser/#/R-CEL-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-212005 https://reactome.org/PathwayBrowser/#/R-CEL-212005 CYP2F1 dehydrogenates 3-methylindole IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-2161814 https://reactome.org/PathwayBrowser/#/R-CEL-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-2161890 https://reactome.org/PathwayBrowser/#/R-CEL-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-2161899 https://reactome.org/PathwayBrowser/#/R-CEL-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-5423647 https://reactome.org/PathwayBrowser/#/R-CEL-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-76354 https://reactome.org/PathwayBrowser/#/R-CEL-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-76397 https://reactome.org/PathwayBrowser/#/R-CEL-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-76416 https://reactome.org/PathwayBrowser/#/R-CEL-76416 Benzene is hydroxylated to phenol IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-76434 https://reactome.org/PathwayBrowser/#/R-CEL-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-76453 https://reactome.org/PathwayBrowser/#/R-CEL-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-76456 https://reactome.org/PathwayBrowser/#/R-CEL-76456 O-atom dealkylation of dextromethorphan IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-76475 https://reactome.org/PathwayBrowser/#/R-CEL-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-9027043 https://reactome.org/PathwayBrowser/#/R-CEL-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-9027302 https://reactome.org/PathwayBrowser/#/R-CEL-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-9027321 https://reactome.org/PathwayBrowser/#/R-CEL-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-9680865 https://reactome.org/PathwayBrowser/#/R-CEL-9680865 CYP3A4, CYP2B6 bind ritonavir IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-9749986 https://reactome.org/PathwayBrowser/#/R-CEL-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-9750016 https://reactome.org/PathwayBrowser/#/R-CEL-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-9753285 https://reactome.org/PathwayBrowser/#/R-CEL-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-9915971 https://reactome.org/PathwayBrowser/#/R-CEL-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Caenorhabditis elegans A0A0M7RF98 R-CEL-9915997 https://reactome.org/PathwayBrowser/#/R-CEL-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Caenorhabditis elegans A0A0N4STN0 R-BTA-164832 https://reactome.org/PathwayBrowser/#/R-BTA-164832 ATPase synthesizes ATP IEA Bos taurus A0A0N4STN0 R-BTA-164834 https://reactome.org/PathwayBrowser/#/R-BTA-164834 Enzyme-bound ATP is released IEA Bos taurus A0A0N4STN0 R-BTA-164840 https://reactome.org/PathwayBrowser/#/R-BTA-164840 ADP and Pi bind to ATPase IEA Bos taurus A0A0N4STN0 R-BTA-8949580 https://reactome.org/PathwayBrowser/#/R-BTA-8949580 F1Fo ATP synthase dimerizes IEA Bos taurus A0A0N4STN0 R-BTA-9837978 https://reactome.org/PathwayBrowser/#/R-BTA-9837978 LONP1 binds mitochondrial inner membrane proteins IEA Bos taurus A0A0N4STN0 R-BTA-9838004 https://reactome.org/PathwayBrowser/#/R-BTA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Bos taurus A0A0N4STN2 R-BTA-163214 https://reactome.org/PathwayBrowser/#/R-BTA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Bos taurus A0A0N4STN2 R-BTA-9709406 https://reactome.org/PathwayBrowser/#/R-BTA-9709406 CO binds to Cytochrome c oxidase IEA Bos taurus A0A0N4STN2 R-BTA-9865579 https://reactome.org/PathwayBrowser/#/R-BTA-9865579 MT-CO1 and MT-CO2 complexes associate, installing heme moieties IEA Bos taurus A0A0N4STN2 R-BTA-9865663 https://reactome.org/PathwayBrowser/#/R-BTA-9865663 MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex IEA Bos taurus A0A0N4SUG9 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio A0A0N4SUG9 R-DRE-417908 https://reactome.org/PathwayBrowser/#/R-DRE-417908 P2RY1 binds ADP IEA Danio rerio A0A0N4SVR5 R-MMU-5672965 https://reactome.org/PathwayBrowser/#/R-MMU-5672965 RAS GEFs promote RAS nucleotide exchange IEA Mus musculus A0A0N4SWI8 R-SSC-1482695 https://reactome.org/PathwayBrowser/#/R-SSC-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Sus scrofa A0A0N4SWI8 R-SSC-75886 https://reactome.org/PathwayBrowser/#/R-SSC-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Sus scrofa A0A0R4IBK5 R-DRE-983140 https://reactome.org/PathwayBrowser/#/R-DRE-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Danio rerio A0A0R4IBK5 R-DRE-983147 https://reactome.org/PathwayBrowser/#/R-DRE-983147 Release of E3 from polyubiquitinated substrate IEA Danio rerio A0A0R4IBK5 R-DRE-983156 https://reactome.org/PathwayBrowser/#/R-DRE-983156 Polyubiquitination of substrate IEA Danio rerio A0A0R4IBK5 R-DRE-983157 https://reactome.org/PathwayBrowser/#/R-DRE-983157 Interaction of E3 with substrate and E2-Ub complex IEA Danio rerio A0A0R4IBL7 R-DRE-448963 https://reactome.org/PathwayBrowser/#/R-DRE-448963 Interaction of MyoD:E protein with MEF2 IEA Danio rerio A0A0R4ICJ7 R-DRE-2025723 https://reactome.org/PathwayBrowser/#/R-DRE-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Danio rerio A0A0R4ICJ7 R-DRE-2046265 https://reactome.org/PathwayBrowser/#/R-DRE-2046265 B4GALTs transfer Gal to the keratan chain IEA Danio rerio A0A0R4ICJ7 R-DRE-2046298 https://reactome.org/PathwayBrowser/#/R-DRE-2046298 B4GALTs transfer Gal to a branch of keratan IEA Danio rerio A0A0R4ICJ7 R-DRE-975919 https://reactome.org/PathwayBrowser/#/R-DRE-975919 Addition of galactose by beta 4-galactosyltransferases IEA Danio rerio A0A0R4ICL4 R-DRE-194079 https://reactome.org/PathwayBrowser/#/R-DRE-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol IEA Danio rerio A0A0R4ICL4 R-DRE-194083 https://reactome.org/PathwayBrowser/#/R-DRE-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol IEA Danio rerio A0A0R4ICL4 R-DRE-194130 https://reactome.org/PathwayBrowser/#/R-DRE-194130 Transport (influx) of bile salts and acids by OATP-A IEA Danio rerio A0A0R4ICL4 R-DRE-879575 https://reactome.org/PathwayBrowser/#/R-DRE-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Danio rerio A0A0R4ICL4 R-DRE-9631987 https://reactome.org/PathwayBrowser/#/R-DRE-9631987 SLCO1B1 transports T3,T4 from extracellular region to cytosol IEA Danio rerio A0A0R4ICL4 R-DRE-9661397 https://reactome.org/PathwayBrowser/#/R-DRE-9661397 SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Danio rerio A0A0R4ICL4 R-DRE-9661799 https://reactome.org/PathwayBrowser/#/R-DRE-9661799 SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) IEA Danio rerio A0A0R4ICL4 R-DRE-9757010 https://reactome.org/PathwayBrowser/#/R-DRE-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Danio rerio A0A0R4ICL4 R-DRE-9794270 https://reactome.org/PathwayBrowser/#/R-DRE-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Danio rerio A0A0R4ICS1 R-DRE-198941 https://reactome.org/PathwayBrowser/#/R-DRE-198941 VCAM1 binds Integrin alpha4beta1 IEA Danio rerio A0A0R4ICS1 R-DRE-202706 https://reactome.org/PathwayBrowser/#/R-DRE-202706 Integrin alpha4beta1 binds JAM2:JAM3 IEA Danio rerio A0A0R4ICS1 R-DRE-9679740 https://reactome.org/PathwayBrowser/#/R-DRE-9679740 ITGA4:ITGB1 binds natalizumab IEA Danio rerio A0A0R4IE17 R-DRE-6783556 https://reactome.org/PathwayBrowser/#/R-DRE-6783556 LIFR:JAKs bind gp130:JAKs:CNTFR IEA Danio rerio A0A0R4IE17 R-DRE-6784189 https://reactome.org/PathwayBrowser/#/R-DRE-6784189 JAKs bind LIFR IEA Danio rerio A0A0R4IE17 R-DRE-6784204 https://reactome.org/PathwayBrowser/#/R-DRE-6784204 JAKs bind OSMR IEA Danio rerio A0A0R4IFI0 R-DRE-165680 https://reactome.org/PathwayBrowser/#/R-DRE-165680 Formation of active mTORC1 complex IEA Danio rerio A0A0R4IFI0 R-DRE-165692 https://reactome.org/PathwayBrowser/#/R-DRE-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Danio rerio A0A0R4IFI0 R-DRE-165718 https://reactome.org/PathwayBrowser/#/R-DRE-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Danio rerio A0A0R4IFI0 R-DRE-377186 https://reactome.org/PathwayBrowser/#/R-DRE-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Danio rerio A0A0R4IFI0 R-DRE-380979 https://reactome.org/PathwayBrowser/#/R-DRE-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Danio rerio A0A0R4IFI0 R-DRE-447074 https://reactome.org/PathwayBrowser/#/R-DRE-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Danio rerio A0A0R4IFI0 R-DRE-5653968 https://reactome.org/PathwayBrowser/#/R-DRE-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Danio rerio A0A0R4IFI0 R-DRE-5672010 https://reactome.org/PathwayBrowser/#/R-DRE-5672010 Active MTORC1 phosphorylates ULK1 IEA Danio rerio A0A0R4IFI0 R-DRE-5672017 https://reactome.org/PathwayBrowser/#/R-DRE-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Danio rerio A0A0R4IFI0 R-DRE-5672824 https://reactome.org/PathwayBrowser/#/R-DRE-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Danio rerio A0A0R4IFI0 R-DRE-5672828 https://reactome.org/PathwayBrowser/#/R-DRE-5672828 mTORC1 phosphorylates AKT1S1 IEA Danio rerio A0A0R4IFI0 R-DRE-5673768 https://reactome.org/PathwayBrowser/#/R-DRE-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Danio rerio A0A0R4IFI0 R-DRE-8944454 https://reactome.org/PathwayBrowser/#/R-DRE-8944454 mTORC1 phosphorylates MAF1 IEA Danio rerio A0A0R4IFI0 R-DRE-8944457 https://reactome.org/PathwayBrowser/#/R-DRE-8944457 MAF1 translocates to the nucleus IEA Danio rerio A0A0R4IFI0 R-DRE-9640195 https://reactome.org/PathwayBrowser/#/R-DRE-9640195 RRAGA,B hydrolyzes GTP IEA Danio rerio A0A0R4IFI0 R-DRE-9645608 https://reactome.org/PathwayBrowser/#/R-DRE-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Danio rerio A0A0R4IFI0 R-DRE-9646468 https://reactome.org/PathwayBrowser/#/R-DRE-9646468 mTORC1 binds RHEB:GTP IEA Danio rerio A0A0R4IFJ4 R-DRE-3323111 https://reactome.org/PathwayBrowser/#/R-DRE-3323111 Cytoslic carboxylases translocate to mitochondrial matrix IEA Danio rerio A0A0R4IFJ4 R-DRE-70501 https://reactome.org/PathwayBrowser/#/R-DRE-70501 PC carboxylates PYR to OA IEA Danio rerio A0A0R4IFY3 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio A0A0R4IFY3 R-DRE-390929 https://reactome.org/PathwayBrowser/#/R-DRE-390929 HTR1 and 5A receptors can bind serotonin IEA Danio rerio A0A0R4IGV4 R-DRE-202706 https://reactome.org/PathwayBrowser/#/R-DRE-202706 Integrin alpha4beta1 binds JAM2:JAM3 IEA Danio rerio A0A0R4IGV4 R-DRE-202709 https://reactome.org/PathwayBrowser/#/R-DRE-202709 JAM2 dimerises IEA Danio rerio A0A0R4IGV4 R-DRE-202721 https://reactome.org/PathwayBrowser/#/R-DRE-202721 JAM2 binds JAM3 IEA Danio rerio A0A0R4IHM6 R-DRE-114558 https://reactome.org/PathwayBrowser/#/R-DRE-114558 Thrombin-activated PARs activate Gq IEA Danio rerio A0A0R4IHM6 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio A0A0R4IHM6 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio A0A0R4IHM6 R-DRE-392195 https://reactome.org/PathwayBrowser/#/R-DRE-392195 Gi activation by P2Y purinoceptor 12 IEA Danio rerio A0A0R4IHM6 R-DRE-400037 https://reactome.org/PathwayBrowser/#/R-DRE-400037 Gi,Go Heterotrimeric G-protein complex dissociates IEA Danio rerio A0A0R4IHM6 R-DRE-400092 https://reactome.org/PathwayBrowser/#/R-DRE-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Danio rerio A0A0R4IHM6 R-DRE-400097 https://reactome.org/PathwayBrowser/#/R-DRE-400097 G-beta:G-gamma inhibits Adenylate cyclase IEA Danio rerio A0A0R4IHM6 R-DRE-420883 https://reactome.org/PathwayBrowser/#/R-DRE-420883 Opsins act as GEFs for G alpha-t IEA Danio rerio A0A0R4IHM6 R-DRE-428750 https://reactome.org/PathwayBrowser/#/R-DRE-428750 Gq activation by TP receptor IEA Danio rerio A0A0R4IHM6 R-DRE-428917 https://reactome.org/PathwayBrowser/#/R-DRE-428917 G13 activation by TP receptor IEA Danio rerio A0A0R4IHM6 R-DRE-432195 https://reactome.org/PathwayBrowser/#/R-DRE-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Danio rerio A0A0R4IHM6 R-DRE-9728664 https://reactome.org/PathwayBrowser/#/R-DRE-9728664 GLP1R binds GLP1R agonists IEA Danio rerio A0A0R4IJ74 R-DRE-6794346 https://reactome.org/PathwayBrowser/#/R-DRE-6794346 NRXNs bind NLGNs IEA Danio rerio A0A0R4IJ74 R-DRE-6797568 https://reactome.org/PathwayBrowser/#/R-DRE-6797568 NRXNs bind CASK:Protein 4.1 IEA Danio rerio A0A0R4IJ75 R-DRE-6814555 https://reactome.org/PathwayBrowser/#/R-DRE-6814555 Integrator complex processes the 3' end of snRNA IEA Danio rerio A0A0R4IJ75 R-DRE-6814559 https://reactome.org/PathwayBrowser/#/R-DRE-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Danio rerio A0A0R4IKG8 R-DRE-70523 https://reactome.org/PathwayBrowser/#/R-DRE-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Danio rerio A0A0R4IKG8 R-DRE-70524 https://reactome.org/PathwayBrowser/#/R-DRE-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Danio rerio A0A0R4IL71 R-DRE-5696872 https://reactome.org/PathwayBrowser/#/R-DRE-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Danio rerio A0A0R4IL71 R-DRE-74730 https://reactome.org/PathwayBrowser/#/R-DRE-74730 Insulin degradation IEA Danio rerio A0A0R4ILD9 R-DRE-72670 https://reactome.org/PathwayBrowser/#/R-DRE-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Danio rerio A0A0R4ILD9 R-DRE-72722 https://reactome.org/PathwayBrowser/#/R-DRE-72722 eIF2 activation IEA Danio rerio A0A0R4ILN1 R-DRE-9668389 https://reactome.org/PathwayBrowser/#/R-DRE-9668389 VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations IEA Danio rerio A0A0R4ILN1 R-DRE-9668395 https://reactome.org/PathwayBrowser/#/R-DRE-9668395 CHMP7 binds CC2D1B IEA Danio rerio A0A0R4ILN1 R-DRE-9668405 https://reactome.org/PathwayBrowser/#/R-DRE-9668405 SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin IEA Danio rerio A0A0R4ILY5 R-DRE-5357757 https://reactome.org/PathwayBrowser/#/R-DRE-5357757 BIRC(cIAP1/2) ubiquitinates RIPK1 IEA Danio rerio A0A0R4ILY5 R-DRE-5357780 https://reactome.org/PathwayBrowser/#/R-DRE-5357780 TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) IEA Danio rerio A0A0R4ILY5 R-DRE-5357845 https://reactome.org/PathwayBrowser/#/R-DRE-5357845 K63polyUb-RIPK1 is deubiquitinated IEA Danio rerio A0A0R4ILY5 R-DRE-5676597 https://reactome.org/PathwayBrowser/#/R-DRE-5676597 TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 IEA Danio rerio A0A0R4ILY5 R-DRE-5696627 https://reactome.org/PathwayBrowser/#/R-DRE-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Danio rerio A0A0R4ILY5 R-DRE-9796342 https://reactome.org/PathwayBrowser/#/R-DRE-9796342 MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 IEA Danio rerio A0A0R4ILY5 R-DRE-9796346 https://reactome.org/PathwayBrowser/#/R-DRE-9796346 MIB2 ubiquitinates RIPK1 at K377, K604, K634 IEA Danio rerio A0A0R4IM91 R-DRE-3295579 https://reactome.org/PathwayBrowser/#/R-DRE-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Danio rerio A0A0R4IMY7 R-DRE-3295579 https://reactome.org/PathwayBrowser/#/R-DRE-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Danio rerio A0A0R4IMY7 R-DRE-6798747 https://reactome.org/PathwayBrowser/#/R-DRE-6798747 Exocytosis of tertiary granule membrane proteins IEA Danio rerio A0A0R4IMY7 R-DRE-6799350 https://reactome.org/PathwayBrowser/#/R-DRE-6799350 Exocytosis of specific granule membrane proteins IEA Danio rerio A0A0R4IMY7 R-DRE-6800426 https://reactome.org/PathwayBrowser/#/R-DRE-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Danio rerio A0A0R4INB9 R-DRE-374248 https://reactome.org/PathwayBrowser/#/R-DRE-374248 Receptor CXCR3 binds ligands CXCL9 to 11 IEA Danio rerio A0A0R4INB9 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio A0A0R4INK2 R-DRE-446204 https://reactome.org/PathwayBrowser/#/R-DRE-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Danio rerio A0A0R4INZ6 R-DRE-1236398 https://reactome.org/PathwayBrowser/#/R-DRE-1236398 ERBB4 binds NRGs or EGF-like ligands IEA Danio rerio A0A0R4INZ6 R-DRE-1250195 https://reactome.org/PathwayBrowser/#/R-DRE-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Danio rerio A0A0R4INZ6 R-DRE-1250220 https://reactome.org/PathwayBrowser/#/R-DRE-1250220 Homodimerization of ERBB4 IEA Danio rerio A0A0R4INZ6 R-DRE-1250315 https://reactome.org/PathwayBrowser/#/R-DRE-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Danio rerio A0A0R4INZ6 R-DRE-1250346 https://reactome.org/PathwayBrowser/#/R-DRE-1250346 Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers IEA Danio rerio A0A0R4INZ6 R-DRE-1250353 https://reactome.org/PathwayBrowser/#/R-DRE-1250353 Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers IEA Danio rerio A0A0R4INZ6 R-DRE-1250370 https://reactome.org/PathwayBrowser/#/R-DRE-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Danio rerio A0A0R4INZ6 R-DRE-1250383 https://reactome.org/PathwayBrowser/#/R-DRE-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Danio rerio A0A0R4INZ6 R-DRE-1306969 https://reactome.org/PathwayBrowser/#/R-DRE-1306969 GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers IEA Danio rerio A0A0R4INZ6 R-DRE-1306972 https://reactome.org/PathwayBrowser/#/R-DRE-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Danio rerio A0A0R4INZ6 R-DRE-1306979 https://reactome.org/PathwayBrowser/#/R-DRE-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Danio rerio A0A0R4INZ6 R-DRE-177922 https://reactome.org/PathwayBrowser/#/R-DRE-177922 EGFR dimerization IEA Danio rerio A0A0R4INZ6 R-DRE-177927 https://reactome.org/PathwayBrowser/#/R-DRE-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 IEA Danio rerio A0A0R4INZ6 R-DRE-177930 https://reactome.org/PathwayBrowser/#/R-DRE-177930 GAB1 phosphorylation by EGFR kinase IEA Danio rerio A0A0R4INZ6 R-DRE-177934 https://reactome.org/PathwayBrowser/#/R-DRE-177934 EGFR autophosphorylation IEA Danio rerio A0A0R4INZ6 R-DRE-177937 https://reactome.org/PathwayBrowser/#/R-DRE-177937 Phosphorylation of EGFR by SRC kinase IEA Danio rerio A0A0R4INZ6 R-DRE-177938 https://reactome.org/PathwayBrowser/#/R-DRE-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Danio rerio A0A0R4INZ6 R-DRE-177939 https://reactome.org/PathwayBrowser/#/R-DRE-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Danio rerio A0A0R4INZ6 R-DRE-177942 https://reactome.org/PathwayBrowser/#/R-DRE-177942 EGFR binds EGF ligand IEA Danio rerio A0A0R4INZ6 R-DRE-177943 https://reactome.org/PathwayBrowser/#/R-DRE-177943 GRB2:SOS1 complex binds to EGF:EGFR complex IEA Danio rerio A0A0R4INZ6 R-DRE-177945 https://reactome.org/PathwayBrowser/#/R-DRE-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Danio rerio A0A0R4INZ6 R-DRE-182969 https://reactome.org/PathwayBrowser/#/R-DRE-182969 Phosphorylation of CBL (EGFR:CBL) IEA Danio rerio A0A0R4INZ6 R-DRE-182993 https://reactome.org/PathwayBrowser/#/R-DRE-182993 Ubiquitination of stimulated EGFR (CBL) IEA Danio rerio A0A0R4INZ6 R-DRE-183036 https://reactome.org/PathwayBrowser/#/R-DRE-183036 Ubiquitination of stimulated EGFR (CBL:GRB2) IEA Danio rerio A0A0R4INZ6 R-DRE-183051 https://reactome.org/PathwayBrowser/#/R-DRE-183051 CBL ubiquitinates Sprouty IEA Danio rerio A0A0R4INZ6 R-DRE-183055 https://reactome.org/PathwayBrowser/#/R-DRE-183055 Binding of CBL to EGFR IEA Danio rerio A0A0R4INZ6 R-DRE-183058 https://reactome.org/PathwayBrowser/#/R-DRE-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Danio rerio A0A0R4INZ6 R-DRE-183067 https://reactome.org/PathwayBrowser/#/R-DRE-183067 Localization of CBL:GRB2 to the membrane IEA Danio rerio A0A0R4INZ6 R-DRE-183089 https://reactome.org/PathwayBrowser/#/R-DRE-183089 CBL binds and ubiquitinates phosphorylated Sprouty IEA Danio rerio A0A0R4INZ6 R-DRE-1963581 https://reactome.org/PathwayBrowser/#/R-DRE-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Danio rerio A0A0R4INZ6 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio A0A0R4INZ6 R-DRE-1963586 https://reactome.org/PathwayBrowser/#/R-DRE-1963586 SRC family kinases phosphorylate ERBB2 IEA Danio rerio A0A0R4INZ6 R-DRE-1977958 https://reactome.org/PathwayBrowser/#/R-DRE-1977958 ERBB4 forms heterodimers with ERBB3 IEA Danio rerio A0A0R4INZ6 R-DRE-212706 https://reactome.org/PathwayBrowser/#/R-DRE-212706 Phospholipase C-gamma1 binds to the activated EGF receptor IEA Danio rerio A0A0R4INZ6 R-DRE-212710 https://reactome.org/PathwayBrowser/#/R-DRE-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Danio rerio A0A0R4INZ6 R-DRE-212713 https://reactome.org/PathwayBrowser/#/R-DRE-212713 Active PLC-gamma1 dissociates from EGFR IEA Danio rerio A0A0R4INZ6 R-DRE-2316434 https://reactome.org/PathwayBrowser/#/R-DRE-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio A0A0R4INZ6 R-DRE-5672965 https://reactome.org/PathwayBrowser/#/R-DRE-5672965 RAS GEFs promote RAS nucleotide exchange IEA Danio rerio A0A0R4INZ6 R-DRE-6785636 https://reactome.org/PathwayBrowser/#/R-DRE-6785636 Phosphorylated ERBB2 heterodimers bind MEMO1 IEA Danio rerio A0A0R4INZ6 R-DRE-8847995 https://reactome.org/PathwayBrowser/#/R-DRE-8847995 Activated ERBB2 binds PTK6 (BRK) IEA Danio rerio A0A0R4INZ6 R-DRE-8848005 https://reactome.org/PathwayBrowser/#/R-DRE-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Danio rerio A0A0R4INZ6 R-DRE-8863804 https://reactome.org/PathwayBrowser/#/R-DRE-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Danio rerio A0A0R4IPV5 R-DRE-1650808 https://reactome.org/PathwayBrowser/#/R-DRE-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Danio rerio A0A0R4IPV5 R-DRE-2002460 https://reactome.org/PathwayBrowser/#/R-DRE-2002460 P4HB binds Collagen chains IEA Danio rerio A0A0R4IPV5 R-DRE-264997 https://reactome.org/PathwayBrowser/#/R-DRE-264997 P4HB mediates disulfide bond formation in Proinsulin IEA Danio rerio A0A0R4IPV5 R-DRE-3341296 https://reactome.org/PathwayBrowser/#/R-DRE-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Danio rerio A0A0R4IPV5 R-DRE-5358336 https://reactome.org/PathwayBrowser/#/R-DRE-5358336 P4HB forms mixed disulphides with Hh precursors IEA Danio rerio A0A0R4IPV5 R-DRE-5358340 https://reactome.org/PathwayBrowser/#/R-DRE-5358340 Autoproteolytic cleavage of Hh precursors IEA Danio rerio A0A0R4IPV5 R-DRE-8948234 https://reactome.org/PathwayBrowser/#/R-DRE-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Danio rerio A0A0R4IPV5 R-DRE-8950456 https://reactome.org/PathwayBrowser/#/R-DRE-8950456 IL12B dimerizes IEA Danio rerio A0A0R4IPV5 R-DRE-9737780 https://reactome.org/PathwayBrowser/#/R-DRE-9737780 MTTP binds lomitapide IEA Danio rerio A0A0R4IQ46 R-DRE-143468 https://reactome.org/PathwayBrowser/#/R-DRE-143468 MEOS oxidizes ethanol to acetaldehyde IEA Danio rerio A0A0R4IQ46 R-DRE-211881 https://reactome.org/PathwayBrowser/#/R-DRE-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Danio rerio A0A0R4IQ46 R-DRE-211966 https://reactome.org/PathwayBrowser/#/R-DRE-211966 CYP2D6 4-hydroxylates debrisoquine IEA Danio rerio A0A0R4IQ46 R-DRE-211968 https://reactome.org/PathwayBrowser/#/R-DRE-211968 CYP2W1 oxidises INDOL IEA Danio rerio A0A0R4IQ46 R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio A0A0R4IQ46 R-DRE-211991 https://reactome.org/PathwayBrowser/#/R-DRE-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Danio rerio A0A0R4IQ46 R-DRE-212005 https://reactome.org/PathwayBrowser/#/R-DRE-212005 CYP2F1 dehydrogenates 3-methylindole IEA Danio rerio A0A0R4IQ46 R-DRE-2161890 https://reactome.org/PathwayBrowser/#/R-DRE-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Danio rerio A0A0R4IQ46 R-DRE-2161899 https://reactome.org/PathwayBrowser/#/R-DRE-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Danio rerio A0A0R4IQ46 R-DRE-76354 https://reactome.org/PathwayBrowser/#/R-DRE-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Danio rerio A0A0R4IQ46 R-DRE-76397 https://reactome.org/PathwayBrowser/#/R-DRE-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Danio rerio A0A0R4IQ46 R-DRE-76416 https://reactome.org/PathwayBrowser/#/R-DRE-76416 Benzene is hydroxylated to phenol IEA Danio rerio A0A0R4IQ46 R-DRE-76434 https://reactome.org/PathwayBrowser/#/R-DRE-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Danio rerio A0A0R4IQ46 R-DRE-76456 https://reactome.org/PathwayBrowser/#/R-DRE-76456 O-atom dealkylation of dextromethorphan IEA Danio rerio A0A0R4IQ46 R-DRE-76475 https://reactome.org/PathwayBrowser/#/R-DRE-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Danio rerio A0A0R4IQ46 R-DRE-9027043 https://reactome.org/PathwayBrowser/#/R-DRE-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Danio rerio A0A0R4IQ46 R-DRE-9749986 https://reactome.org/PathwayBrowser/#/R-DRE-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Danio rerio A0A0R4IQ46 R-DRE-9750016 https://reactome.org/PathwayBrowser/#/R-DRE-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Danio rerio A0A0R4IQ46 R-DRE-9915971 https://reactome.org/PathwayBrowser/#/R-DRE-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Danio rerio A0A0R4IQ46 R-DRE-9915997 https://reactome.org/PathwayBrowser/#/R-DRE-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Danio rerio A0A0R4IQG7 R-DRE-418436 https://reactome.org/PathwayBrowser/#/R-DRE-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Danio rerio A0A0R4IR84 R-DRE-2022860 https://reactome.org/PathwayBrowser/#/R-DRE-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Danio rerio A0A0R4IR84 R-DRE-2022887 https://reactome.org/PathwayBrowser/#/R-DRE-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Danio rerio A0A0R4IRN2 R-DRE-373075 https://reactome.org/PathwayBrowser/#/R-DRE-373075 Metabotropic glutamate receptors bind glutamate IEA Danio rerio A0A0R4IRN2 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio A0A0R4IRS4 R-DRE-5649705 https://reactome.org/PathwayBrowser/#/R-DRE-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Danio rerio A0A0R4IRS4 R-DRE-5649723 https://reactome.org/PathwayBrowser/#/R-DRE-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Danio rerio A0A0R4IRS4 R-DRE-5649734 https://reactome.org/PathwayBrowser/#/R-DRE-5649734 LIG3 ligates NEIL1,NEIL2-generated single strand break IEA Danio rerio A0A0R4IT00 R-DRE-2046088 https://reactome.org/PathwayBrowser/#/R-DRE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Danio rerio A0A0R4IT00 R-DRE-2046094 https://reactome.org/PathwayBrowser/#/R-DRE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Danio rerio A0A0R4IT00 R-DRE-548800 https://reactome.org/PathwayBrowser/#/R-DRE-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Danio rerio A0A0R4ITC5 R-DRE-3451153 https://reactome.org/PathwayBrowser/#/R-DRE-3451153 Beta-catenin recruits TRRAP/KAT5 HAT components IEA Danio rerio A0A0R4ITC5 R-DRE-5690080 https://reactome.org/PathwayBrowser/#/R-DRE-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Danio rerio A0A0R4ITJ9 R-DRE-6798747 https://reactome.org/PathwayBrowser/#/R-DRE-6798747 Exocytosis of tertiary granule membrane proteins IEA Danio rerio A0A0R4ITJ9 R-DRE-6799350 https://reactome.org/PathwayBrowser/#/R-DRE-6799350 Exocytosis of specific granule membrane proteins IEA Danio rerio A0A0R4IU39 R-DRE-141429 https://reactome.org/PathwayBrowser/#/R-DRE-141429 Inactivation of APC/C via CDC20 sequestration IEA Danio rerio A0A0R4IU39 R-DRE-174122 https://reactome.org/PathwayBrowser/#/R-DRE-174122 Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 IEA Danio rerio A0A0R4IU39 R-DRE-174159 https://reactome.org/PathwayBrowser/#/R-DRE-174159 Ubiquitination of Emi1 by SCF-beta-TrCP IEA Danio rerio A0A0R4IU39 R-DRE-174174 https://reactome.org/PathwayBrowser/#/R-DRE-174174 Phosphorylation of the Emi1 DSGxxS degron by Plk1 IEA Danio rerio A0A0R4IU39 R-DRE-174235 https://reactome.org/PathwayBrowser/#/R-DRE-174235 Association of Emi1 with Cdc20 IEA Danio rerio A0A0R4IU39 R-DRE-5696958 https://reactome.org/PathwayBrowser/#/R-DRE-5696958 USP44 deubiquitinates CDC20 IEA Danio rerio A0A0R4IU63 R-DRE-373075 https://reactome.org/PathwayBrowser/#/R-DRE-373075 Metabotropic glutamate receptors bind glutamate IEA Danio rerio A0A0R4IU63 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio A0A0R4IU63 R-DRE-6794347 https://reactome.org/PathwayBrowser/#/R-DRE-6794347 Homer1,2,3 dimerizes IEA Danio rerio A0A0R4IU63 R-DRE-6794355 https://reactome.org/PathwayBrowser/#/R-DRE-6794355 Homer1,2,3 binds mGluR1a,5 IEA Danio rerio A0A0R4IUJ2 R-DRE-114542 https://reactome.org/PathwayBrowser/#/R-DRE-114542 RAC1,RAC2,RHOG activate PI3K IEA Danio rerio A0A0R4IUJ2 R-DRE-1433514 https://reactome.org/PathwayBrowser/#/R-DRE-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Danio rerio A0A0R4IUJ2 R-DRE-1676048 https://reactome.org/PathwayBrowser/#/R-DRE-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Danio rerio A0A0R4IUJ2 R-DRE-1676109 https://reactome.org/PathwayBrowser/#/R-DRE-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Danio rerio A0A0R4IUJ2 R-DRE-205262 https://reactome.org/PathwayBrowser/#/R-DRE-205262 Direct recruitment of PI3K to p-KIT IEA Danio rerio A0A0R4IUJ2 R-DRE-2316434 https://reactome.org/PathwayBrowser/#/R-DRE-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio A0A0R4IUJ2 R-DRE-416358 https://reactome.org/PathwayBrowser/#/R-DRE-416358 G alpha (q) inhibits PI3K alpha IEA Danio rerio A0A0R4IUJ2 R-DRE-437162 https://reactome.org/PathwayBrowser/#/R-DRE-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Danio rerio A0A0R4IUJ2 R-DRE-879917 https://reactome.org/PathwayBrowser/#/R-DRE-879917 CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated IEA Danio rerio A0A0R4IUJ2 R-DRE-9014294 https://reactome.org/PathwayBrowser/#/R-DRE-9014294 RAC2 binds effectors at the plasma membrane IEA Danio rerio A0A0R4IUJ2 R-DRE-9021660 https://reactome.org/PathwayBrowser/#/R-DRE-9021660 PI3K binds membrane-associated estrogen receptors IEA Danio rerio A0A0R4IUJ2 R-DRE-912627 https://reactome.org/PathwayBrowser/#/R-DRE-912627 CBL ubiquitinates PI3K IEA Danio rerio A0A0R4IUS5 R-DRE-983140 https://reactome.org/PathwayBrowser/#/R-DRE-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Danio rerio A0A0R4IUS5 R-DRE-983147 https://reactome.org/PathwayBrowser/#/R-DRE-983147 Release of E3 from polyubiquitinated substrate IEA Danio rerio A0A0R4IUS5 R-DRE-983156 https://reactome.org/PathwayBrowser/#/R-DRE-983156 Polyubiquitination of substrate IEA Danio rerio A0A0R4IUS5 R-DRE-983157 https://reactome.org/PathwayBrowser/#/R-DRE-983157 Interaction of E3 with substrate and E2-Ub complex IEA Danio rerio A0A0R4IVA4 R-DRE-174124 https://reactome.org/PathwayBrowser/#/R-DRE-174124 Dephosphorylation of phospho-Cdh1 IEA Danio rerio A0A0R4IVA4 R-DRE-5692749 https://reactome.org/PathwayBrowser/#/R-DRE-5692749 CDC14A,B bind MAPK6 IEA Danio rerio A0A0R4IVA4 R-DRE-5692754 https://reactome.org/PathwayBrowser/#/R-DRE-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Danio rerio A0A0R4IVA4 R-DRE-5692764 https://reactome.org/PathwayBrowser/#/R-DRE-5692764 MAPK6 binds CCND3 IEA Danio rerio A0A0R4IVU6 R-DRE-482772 https://reactome.org/PathwayBrowser/#/R-DRE-482772 Release of platelet cytosolic components IEA Danio rerio A0A0R4IVV0 R-DRE-9737780 https://reactome.org/PathwayBrowser/#/R-DRE-9737780 MTTP binds lomitapide IEA Danio rerio A0A0R4IWG0 R-DRE-177922 https://reactome.org/PathwayBrowser/#/R-DRE-177922 EGFR dimerization IEA Danio rerio A0A0R4IWG0 R-DRE-177927 https://reactome.org/PathwayBrowser/#/R-DRE-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 IEA Danio rerio A0A0R4IWG0 R-DRE-177930 https://reactome.org/PathwayBrowser/#/R-DRE-177930 GAB1 phosphorylation by EGFR kinase IEA Danio rerio A0A0R4IWG0 R-DRE-177934 https://reactome.org/PathwayBrowser/#/R-DRE-177934 EGFR autophosphorylation IEA Danio rerio A0A0R4IWG0 R-DRE-177937 https://reactome.org/PathwayBrowser/#/R-DRE-177937 Phosphorylation of EGFR by SRC kinase IEA Danio rerio A0A0R4IWG0 R-DRE-177938 https://reactome.org/PathwayBrowser/#/R-DRE-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Danio rerio A0A0R4IWG0 R-DRE-177939 https://reactome.org/PathwayBrowser/#/R-DRE-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Danio rerio A0A0R4IWG0 R-DRE-177942 https://reactome.org/PathwayBrowser/#/R-DRE-177942 EGFR binds EGF ligand IEA Danio rerio A0A0R4IWG0 R-DRE-177943 https://reactome.org/PathwayBrowser/#/R-DRE-177943 GRB2:SOS1 complex binds to EGF:EGFR complex IEA Danio rerio A0A0R4IWG0 R-DRE-177945 https://reactome.org/PathwayBrowser/#/R-DRE-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Danio rerio A0A0R4IWG0 R-DRE-182969 https://reactome.org/PathwayBrowser/#/R-DRE-182969 Phosphorylation of CBL (EGFR:CBL) IEA Danio rerio A0A0R4IWG0 R-DRE-182993 https://reactome.org/PathwayBrowser/#/R-DRE-182993 Ubiquitination of stimulated EGFR (CBL) IEA Danio rerio A0A0R4IWG0 R-DRE-183036 https://reactome.org/PathwayBrowser/#/R-DRE-183036 Ubiquitination of stimulated EGFR (CBL:GRB2) IEA Danio rerio A0A0R4IWG0 R-DRE-183051 https://reactome.org/PathwayBrowser/#/R-DRE-183051 CBL ubiquitinates Sprouty IEA Danio rerio A0A0R4IWG0 R-DRE-183055 https://reactome.org/PathwayBrowser/#/R-DRE-183055 Binding of CBL to EGFR IEA Danio rerio A0A0R4IWG0 R-DRE-183058 https://reactome.org/PathwayBrowser/#/R-DRE-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Danio rerio A0A0R4IWG0 R-DRE-183067 https://reactome.org/PathwayBrowser/#/R-DRE-183067 Localization of CBL:GRB2 to the membrane IEA Danio rerio A0A0R4IWG0 R-DRE-183089 https://reactome.org/PathwayBrowser/#/R-DRE-183089 CBL binds and ubiquitinates phosphorylated Sprouty IEA Danio rerio A0A0R4IWG0 R-DRE-212706 https://reactome.org/PathwayBrowser/#/R-DRE-212706 Phospholipase C-gamma1 binds to the activated EGF receptor IEA Danio rerio A0A0R4IWG0 R-DRE-212710 https://reactome.org/PathwayBrowser/#/R-DRE-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Danio rerio A0A0R4IWG0 R-DRE-212713 https://reactome.org/PathwayBrowser/#/R-DRE-212713 Active PLC-gamma1 dissociates from EGFR IEA Danio rerio A0A0R4IWG0 R-DRE-2316434 https://reactome.org/PathwayBrowser/#/R-DRE-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Danio rerio A0A0R4IWG0 R-DRE-5672965 https://reactome.org/PathwayBrowser/#/R-DRE-5672965 RAS GEFs promote RAS nucleotide exchange IEA Danio rerio A0A0R4IXF6 R-DRE-5690080 https://reactome.org/PathwayBrowser/#/R-DRE-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Danio rerio A0A0R4IY06 R-DRE-8858298 https://reactome.org/PathwayBrowser/#/R-DRE-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Danio rerio A0A0R4IZ84 R-DRE-927813 https://reactome.org/PathwayBrowser/#/R-DRE-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Danio rerio A0A0R4IZ84 R-DRE-927836 https://reactome.org/PathwayBrowser/#/R-DRE-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Danio rerio A0A0R4IZR5 R-DRE-2466068 https://reactome.org/PathwayBrowser/#/R-DRE-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Danio rerio A0A0R4IZR5 R-DRE-2468039 https://reactome.org/PathwayBrowser/#/R-DRE-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Danio rerio A0A0R4IZR5 R-DRE-2468293 https://reactome.org/PathwayBrowser/#/R-DRE-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Danio rerio A0A0R4IZR5 R-DRE-2473152 https://reactome.org/PathwayBrowser/#/R-DRE-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Danio rerio A0A0R4IZR5 R-DRE-2545253 https://reactome.org/PathwayBrowser/#/R-DRE-2545253 Deacetylation of cohesin IEA Danio rerio A0A0R4J8D5 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A0R4J8D5 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A0R4J8D5 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A0R4J8D5 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A0R4J8D5 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A0S0WGR0 R-DME-9603775 https://reactome.org/PathwayBrowser/#/R-DME-9603775 PEX3:PEX19:class I PMP dissociates IEA Drosophila melanogaster A0A0S0WGR0 R-DME-9603784 https://reactome.org/PathwayBrowser/#/R-DME-9603784 PEX19:class I PMP binds PEX3 IEA Drosophila melanogaster A0A0S0WGR0 R-DME-9603804 https://reactome.org/PathwayBrowser/#/R-DME-9603804 PEX19 binds class I peroxisomal membrane proteins IEA Drosophila melanogaster A0A0S0WMT8 R-DME-167419 https://reactome.org/PathwayBrowser/#/R-DME-167419 The receptor:G-protein complex releases GDP IEA Drosophila melanogaster A0A0S0WMT8 R-DME-167429 https://reactome.org/PathwayBrowser/#/R-DME-167429 The receptor:G-protein complex binds GTP IEA Drosophila melanogaster A0A0S0WMT8 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster A0A0S0WMT8 R-DME-391934 https://reactome.org/PathwayBrowser/#/R-DME-391934 DP2 receptor can bind PGD2 IEA Drosophila melanogaster A0A0S0WMT8 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster A0A0S0WMT8 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster A0A0S0WMT8 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster A0A0S0WNY8 R-DME-622325 https://reactome.org/PathwayBrowser/#/R-DME-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Drosophila melanogaster A0A0S0WNY8 R-DME-622326 https://reactome.org/PathwayBrowser/#/R-DME-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Drosophila melanogaster A0A0S0WNY8 R-DME-629588 https://reactome.org/PathwayBrowser/#/R-DME-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Drosophila melanogaster A0A0S0WNY8 R-DME-629595 https://reactome.org/PathwayBrowser/#/R-DME-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Drosophila melanogaster A0A0S0WNY8 R-DME-629596 https://reactome.org/PathwayBrowser/#/R-DME-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Drosophila melanogaster A0A0S0WNY8 R-DME-629599 https://reactome.org/PathwayBrowser/#/R-DME-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Drosophila melanogaster A0A0S0WNY8 R-DME-6798747 https://reactome.org/PathwayBrowser/#/R-DME-6798747 Exocytosis of tertiary granule membrane proteins IEA Drosophila melanogaster A0A0S0WNY8 R-DME-6799350 https://reactome.org/PathwayBrowser/#/R-DME-6799350 Exocytosis of specific granule membrane proteins IEA Drosophila melanogaster A0A0S3UPI6 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A0S3UPI6 R-GGA-388863 https://reactome.org/PathwayBrowser/#/R-GGA-388863 Neuropeptide Y receptors can bind neuropeptide Y-related peptides IEA Gallus gallus A0A0S3UPI6 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A0S3UPI6 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A0S4XR36 R-CEL-6798747 https://reactome.org/PathwayBrowser/#/R-CEL-6798747 Exocytosis of tertiary granule membrane proteins IEA Caenorhabditis elegans A0A0S4XR36 R-CEL-6799350 https://reactome.org/PathwayBrowser/#/R-CEL-6799350 Exocytosis of specific granule membrane proteins IEA Caenorhabditis elegans A0A0S4XR36 R-CEL-6800426 https://reactome.org/PathwayBrowser/#/R-CEL-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Caenorhabditis elegans A0A0S4XR36 R-CEL-983140 https://reactome.org/PathwayBrowser/#/R-CEL-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Caenorhabditis elegans A0A0S4XR36 R-CEL-983147 https://reactome.org/PathwayBrowser/#/R-CEL-983147 Release of E3 from polyubiquitinated substrate IEA Caenorhabditis elegans A0A0S4XR36 R-CEL-983156 https://reactome.org/PathwayBrowser/#/R-CEL-983156 Polyubiquitination of substrate IEA Caenorhabditis elegans A0A0S4XR36 R-CEL-983157 https://reactome.org/PathwayBrowser/#/R-CEL-983157 Interaction of E3 with substrate and E2-Ub complex IEA Caenorhabditis elegans A0A0U1RNF2 R-MMU-8856945 https://reactome.org/PathwayBrowser/#/R-MMU-8856945 PP2A methylation by LCMT1 IEA Mus musculus A0A0U1RQ46 R-MMU-975040 https://reactome.org/PathwayBrowser/#/R-MMU-975040 KRAB-ZNF / KAP Interaction IEA Mus musculus A0A0U1RQ46 R-MMU-9842833 https://reactome.org/PathwayBrowser/#/R-MMU-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Mus musculus A0A0U1RRP3 R-RNO-159101 https://reactome.org/PathwayBrowser/#/R-RNO-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Rattus norvegicus A0A0U1RRP3 R-RNO-72180 https://reactome.org/PathwayBrowser/#/R-RNO-72180 Cleavage of mRNA at the 3'-end IEA Rattus norvegicus A0A0U1RRP3 R-RNO-72185 https://reactome.org/PathwayBrowser/#/R-RNO-72185 mRNA polyadenylation IEA Rattus norvegicus A0A0U1RRP3 R-RNO-75097 https://reactome.org/PathwayBrowser/#/R-RNO-75097 Transport of the export-competent mRNP complex through the NPC IEA Rattus norvegicus A0A0U1RRP3 R-RNO-75098 https://reactome.org/PathwayBrowser/#/R-RNO-75098 mRNP complex dissociates from cytosolic face of NPC IEA Rattus norvegicus A0A0U1RRP3 R-RNO-927813 https://reactome.org/PathwayBrowser/#/R-RNO-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Rattus norvegicus A0A0U1RRP3 R-RNO-927832 https://reactome.org/PathwayBrowser/#/R-RNO-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Rattus norvegicus A0A0U1RRP3 R-RNO-927836 https://reactome.org/PathwayBrowser/#/R-RNO-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Rattus norvegicus A0A0U1RRP3 R-RNO-927889 https://reactome.org/PathwayBrowser/#/R-RNO-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Rattus norvegicus A0A0U1RRP3 R-RNO-9770141 https://reactome.org/PathwayBrowser/#/R-RNO-9770141 Formation of the Spliceosomal C* complex IEA Rattus norvegicus A0A0U1RRP3 R-RNO-9770236 https://reactome.org/PathwayBrowser/#/R-RNO-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Rattus norvegicus A0A0U1RRP3 R-RNO-9794542 https://reactome.org/PathwayBrowser/#/R-RNO-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Rattus norvegicus A0A0U1RRS5 R-RNO-927813 https://reactome.org/PathwayBrowser/#/R-RNO-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Rattus norvegicus A0A0U1RRS5 R-RNO-927830 https://reactome.org/PathwayBrowser/#/R-RNO-927830 Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex IEA Rattus norvegicus A0A0U1RRS5 R-RNO-927836 https://reactome.org/PathwayBrowser/#/R-RNO-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Rattus norvegicus A0A0U1RRS6 R-RNO-927813 https://reactome.org/PathwayBrowser/#/R-RNO-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Rattus norvegicus A0A0U1RRS6 R-RNO-927832 https://reactome.org/PathwayBrowser/#/R-RNO-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Rattus norvegicus A0A0U1RRS6 R-RNO-927836 https://reactome.org/PathwayBrowser/#/R-RNO-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Rattus norvegicus A0A0U1RRS6 R-RNO-927889 https://reactome.org/PathwayBrowser/#/R-RNO-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Rattus norvegicus A0A0U1RRT4 R-RNO-6807872 https://reactome.org/PathwayBrowser/#/R-RNO-6807872 Active ARF recruits coatomer IEA Rattus norvegicus A0A0U1RRT4 R-RNO-6807875 https://reactome.org/PathwayBrowser/#/R-RNO-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Rattus norvegicus A0A0U1RRT4 R-RNO-6807877 https://reactome.org/PathwayBrowser/#/R-RNO-6807877 ARFGAPs stimulate ARF GTPase activity IEA Rattus norvegicus A0A0U1RRT4 R-RNO-6809003 https://reactome.org/PathwayBrowser/#/R-RNO-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Rattus norvegicus A0A0U1RRT4 R-RNO-6809006 https://reactome.org/PathwayBrowser/#/R-RNO-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Rattus norvegicus A0A0U1RRT4 R-RNO-6809010 https://reactome.org/PathwayBrowser/#/R-RNO-6809010 COPI vesicle uncoating IEA Rattus norvegicus A0A0U1RRT4 R-RNO-6809011 https://reactome.org/PathwayBrowser/#/R-RNO-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Rattus norvegicus A0A0U1RRT4 R-RNO-6811412 https://reactome.org/PathwayBrowser/#/R-RNO-6811412 Active ARF recruits coatomer to the Golgi IEA Rattus norvegicus A0A0U1RRT4 R-RNO-6811417 https://reactome.org/PathwayBrowser/#/R-RNO-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Rattus norvegicus A0A0U1RRT4 R-RNO-6811418 https://reactome.org/PathwayBrowser/#/R-RNO-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Rattus norvegicus A0A0U1RRT4 R-RNO-6811423 https://reactome.org/PathwayBrowser/#/R-RNO-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Rattus norvegicus A0A0U1RRT4 R-RNO-6811426 https://reactome.org/PathwayBrowser/#/R-RNO-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Rattus norvegicus A0A0U1RRT4 R-RNO-6811427 https://reactome.org/PathwayBrowser/#/R-RNO-6811427 COPI vesicle uncoating at the ER IEA Rattus norvegicus A0A0U1RRU5 R-RNO-2730861 https://reactome.org/PathwayBrowser/#/R-RNO-2730861 Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 IEA Rattus norvegicus A0A0U1RRU5 R-RNO-2730876 https://reactome.org/PathwayBrowser/#/R-RNO-2730876 Phosphorylation of IKK-beta by TAK1 IEA Rattus norvegicus A0A0U1RRU5 R-RNO-2730900 https://reactome.org/PathwayBrowser/#/R-RNO-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Rattus norvegicus A0A0U1RRU5 R-RNO-446870 https://reactome.org/PathwayBrowser/#/R-RNO-446870 Polyubiquitinated TRAF6 binds the TAK1 complex IEA Rattus norvegicus A0A0U1RRU5 R-RNO-450187 https://reactome.org/PathwayBrowser/#/R-RNO-450187 TAK1 is activated within the TAK1 complex IEA Rattus norvegicus A0A0U1RRU5 R-RNO-450337 https://reactome.org/PathwayBrowser/#/R-RNO-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Rattus norvegicus A0A0U1RRU5 R-RNO-450346 https://reactome.org/PathwayBrowser/#/R-RNO-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Rattus norvegicus A0A0U1RRU5 R-RNO-5357860 https://reactome.org/PathwayBrowser/#/R-RNO-5357860 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex IEA Rattus norvegicus A0A0U1RRU5 R-RNO-5607732 https://reactome.org/PathwayBrowser/#/R-RNO-5607732 K63polyUb-TAK1 autophosphorylates IEA Rattus norvegicus A0A0U1RRU5 R-RNO-5607742 https://reactome.org/PathwayBrowser/#/R-RNO-5607742 K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta IEA Rattus norvegicus A0A0U1RRU5 R-RNO-5607759 https://reactome.org/PathwayBrowser/#/R-RNO-5607759 TRIKA2 binds K63polyUb-TRAF6 oligomer IEA Rattus norvegicus A0A0U1RRU5 R-RNO-5696534 https://reactome.org/PathwayBrowser/#/R-RNO-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Rattus norvegicus A0A0U1RRU5 R-RNO-688985 https://reactome.org/PathwayBrowser/#/R-RNO-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex IEA Rattus norvegicus A0A0U1RRU5 R-RNO-706479 https://reactome.org/PathwayBrowser/#/R-RNO-706479 TAK1 is activated IEA Rattus norvegicus A0A0U1RRU5 R-RNO-727819 https://reactome.org/PathwayBrowser/#/R-RNO-727819 TAK1 phosphorylates MKK6 IEA Rattus norvegicus A0A0U1RRU5 R-RNO-936947 https://reactome.org/PathwayBrowser/#/R-RNO-936947 Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex IEA Rattus norvegicus A0A0U1RRU5 R-RNO-936951 https://reactome.org/PathwayBrowser/#/R-RNO-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Rattus norvegicus A0A0U1RRU5 R-RNO-936960 https://reactome.org/PathwayBrowser/#/R-RNO-936960 Activated TRAF6:p-IRAK2 interacts with TAK1 complex IEA Rattus norvegicus A0A0U1RRU5 R-RNO-936991 https://reactome.org/PathwayBrowser/#/R-RNO-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Rattus norvegicus A0A0U1RRU5 R-RNO-937075 https://reactome.org/PathwayBrowser/#/R-RNO-937075 Phosphorylated TAK1 leaves activated TLR receptor complex IEA Rattus norvegicus A0A0U1RRU5 R-RNO-9645406 https://reactome.org/PathwayBrowser/#/R-RNO-9645406 ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) IEA Rattus norvegicus A0A0U1RRU5 R-RNO-9645442 https://reactome.org/PathwayBrowser/#/R-RNO-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Rattus norvegicus A0A0U1RRU5 R-RNO-975097 https://reactome.org/PathwayBrowser/#/R-RNO-975097 Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation IEA Rattus norvegicus A0A0U1RRU5 R-RNO-975103 https://reactome.org/PathwayBrowser/#/R-RNO-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Rattus norvegicus A0A0U1RRW3 R-RNO-3371518 https://reactome.org/PathwayBrowser/#/R-RNO-3371518 SIRT1 binds to HSF1 IEA Rattus norvegicus A0A0U1RRW8 R-RNO-3318486 https://reactome.org/PathwayBrowser/#/R-RNO-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Rattus norvegicus A0A0U1RRW8 R-RNO-482772 https://reactome.org/PathwayBrowser/#/R-RNO-482772 Release of platelet cytosolic components IEA Rattus norvegicus A0A0U1RRW8 R-RNO-6805620 https://reactome.org/PathwayBrowser/#/R-RNO-6805620 KAT6A and PML bind TP53 IEA Rattus norvegicus A0A0U1RRW8 R-RNO-6805638 https://reactome.org/PathwayBrowser/#/R-RNO-6805638 KAT6A acetylates TP53 IEA Rattus norvegicus A0A0U1RRW8 R-RNO-6805640 https://reactome.org/PathwayBrowser/#/R-RNO-6805640 AKT phosphorylates KAT6A IEA Rattus norvegicus A0A0U1RRW8 R-RNO-6805650 https://reactome.org/PathwayBrowser/#/R-RNO-6805650 MTA2-NuRD complex deacetylates TP53 IEA Rattus norvegicus A0A0U1RS25 R-RNO-927789 https://reactome.org/PathwayBrowser/#/R-RNO-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Rattus norvegicus A0A0U1RS25 R-RNO-927813 https://reactome.org/PathwayBrowser/#/R-RNO-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Rattus norvegicus A0A0U1RS25 R-RNO-927830 https://reactome.org/PathwayBrowser/#/R-RNO-927830 Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex IEA Rattus norvegicus A0A0U1RS25 R-RNO-927832 https://reactome.org/PathwayBrowser/#/R-RNO-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Rattus norvegicus A0A0U1RS25 R-RNO-927836 https://reactome.org/PathwayBrowser/#/R-RNO-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Rattus norvegicus A0A0U1RS25 R-RNO-927889 https://reactome.org/PathwayBrowser/#/R-RNO-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Rattus norvegicus A0A0U1RS26 R-RNO-9770141 https://reactome.org/PathwayBrowser/#/R-RNO-9770141 Formation of the Spliceosomal C* complex IEA Rattus norvegicus A0A0U1RS26 R-RNO-9770236 https://reactome.org/PathwayBrowser/#/R-RNO-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Rattus norvegicus A0A0U1RS29 R-RNO-9660557 https://reactome.org/PathwayBrowser/#/R-RNO-9660557 RAS:GTP binds RAL GDS proteins IEA Rattus norvegicus A0A0U1RS44 R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Sus scrofa A0A0U1RS44 R-SSC-6799179 https://reactome.org/PathwayBrowser/#/R-SSC-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Sus scrofa A0A0U1RS44 R-SSC-6799191 https://reactome.org/PathwayBrowser/#/R-SSC-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Sus scrofa A0A0U1RS44 R-SSC-6799196 https://reactome.org/PathwayBrowser/#/R-SSC-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Sus scrofa A0A0U1RS44 R-SSC-6799202 https://reactome.org/PathwayBrowser/#/R-SSC-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Sus scrofa A0A0U1RVK6 R-DME-70479 https://reactome.org/PathwayBrowser/#/R-DME-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Drosophila melanogaster A0A0U2ETD0 R-SSC-2993898 https://reactome.org/PathwayBrowser/#/R-SSC-2993898 VRK1/VRK2 phosphorylate BANF1 IEA Sus scrofa A0A0U2ETD0 R-SSC-2995376 https://reactome.org/PathwayBrowser/#/R-SSC-2995376 BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins IEA Sus scrofa A0A0U2ETD0 R-SSC-5229194 https://reactome.org/PathwayBrowser/#/R-SSC-5229194 Depolymerization of lamin filaments after PKC-mediated phosphorylation IEA Sus scrofa A0A0U2ETD0 R-SSC-9013438 https://reactome.org/PathwayBrowser/#/R-SSC-9013438 RHOD binds effectors at the endosome membrane IEA Sus scrofa A0A0U2ETD0 R-SSC-9014467 https://reactome.org/PathwayBrowser/#/R-SSC-9014467 RHOG binds effectors at the ER membrane IEA Sus scrofa A0A0U2ETD0 R-SSC-9609921 https://reactome.org/PathwayBrowser/#/R-SSC-9609921 SGTA binds Tail-anchored protein IEA Sus scrofa A0A0U2ETD0 R-SSC-9691174 https://reactome.org/PathwayBrowser/#/R-SSC-9691174 RAC1 binds effectors at the ER membrane IEA Sus scrofa A0A0U2ETD0 R-SSC-9714481 https://reactome.org/PathwayBrowser/#/R-SSC-9714481 RAC2 binds effectors at the ER membrane IEA Sus scrofa A0A0U2ETD0 R-SSC-9714691 https://reactome.org/PathwayBrowser/#/R-SSC-9714691 RAC3 binds ER effectors IEA Sus scrofa A0A0U4VU53 R-GGA-9761027 https://reactome.org/PathwayBrowser/#/R-GGA-9761027 ZEB2 binds SP1 IEA Gallus gallus A0A0U5J4Y0 R-RNO-5668414 https://reactome.org/PathwayBrowser/#/R-RNO-5668414 TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK IEA Rattus norvegicus A0A0U5J4Y0 R-RNO-5668454 https://reactome.org/PathwayBrowser/#/R-RNO-5668454 K63polyUb-cIAP1,2 ubiquitinates TRAF3 IEA Rattus norvegicus A0A0U5J4Y0 R-RNO-5668481 https://reactome.org/PathwayBrowser/#/R-RNO-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Rattus norvegicus A0A0U5J4Y0 R-RNO-5668534 https://reactome.org/PathwayBrowser/#/R-RNO-5668534 cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK IEA Rattus norvegicus A0A0U5J4Y0 R-RNO-5669023 https://reactome.org/PathwayBrowser/#/R-RNO-5669023 TWEAK binds FN14 IEA Rattus norvegicus A0A0U5J4Y0 R-RNO-5676598 https://reactome.org/PathwayBrowser/#/R-RNO-5676598 TRAF2:cIAP1/2 complex binds FN14:TWEAK IEA Rattus norvegicus A0A0U5J7B5 R-RNO-141139 https://reactome.org/PathwayBrowser/#/R-RNO-141139 Trimerization of TRAIL:TRAIL receptor complex IEA Rattus norvegicus A0A0U5J7B5 R-RNO-141156 https://reactome.org/PathwayBrowser/#/R-RNO-141156 TRAIL-mediated dimerization of procaspase-8 IEA Rattus norvegicus A0A0U5J7B5 R-RNO-3371359 https://reactome.org/PathwayBrowser/#/R-RNO-3371359 FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling IEA Rattus norvegicus A0A0U5J7B5 R-RNO-3465429 https://reactome.org/PathwayBrowser/#/R-RNO-3465429 FLIP(S) and procaspase-8 form heterodimer IEA Rattus norvegicus A0A0U5J7B5 R-RNO-3465448 https://reactome.org/PathwayBrowser/#/R-RNO-3465448 Caspase-8 and FLIP(L) processing at DISC IEA Rattus norvegicus A0A0U5J7B5 R-RNO-5675456 https://reactome.org/PathwayBrowser/#/R-RNO-5675456 FLIP(L) and procaspase-8 form heterodimer IEA Rattus norvegicus A0A0U5J7B5 R-RNO-75146 https://reactome.org/PathwayBrowser/#/R-RNO-75146 TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 IEA Rattus norvegicus A0A0U5J7B5 R-RNO-75187 https://reactome.org/PathwayBrowser/#/R-RNO-75187 TRAIL:TRAIL receptor trimers bind FADD IEA Rattus norvegicus A0A0U5J7B5 R-RNO-75238 https://reactome.org/PathwayBrowser/#/R-RNO-75238 TRAIL binds TRAIL receptors IEA Rattus norvegicus A0A0U5JAK9 R-CFA-5675947 https://reactome.org/PathwayBrowser/#/R-CFA-5675947 TNFSF18 binds TNFRSF18 IEA Canis familiaris A0A126GUN8 R-DME-6811426 https://reactome.org/PathwayBrowser/#/R-DME-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Drosophila melanogaster A0A126GUN8 R-DME-983259 https://reactome.org/PathwayBrowser/#/R-DME-983259 Kinesins move along microtubules consuming ATP IEA Drosophila melanogaster A0A131MB42 R-CEL-382096 https://reactome.org/PathwayBrowser/#/R-CEL-382096 Formation of NR-NCOR Corepressor Complex IEA Caenorhabditis elegans A0A131MB42 R-CEL-5334854 https://reactome.org/PathwayBrowser/#/R-CEL-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Caenorhabditis elegans A0A131MB42 R-CEL-5634103 https://reactome.org/PathwayBrowser/#/R-CEL-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Caenorhabditis elegans A0A131MB42 R-CEL-9009817 https://reactome.org/PathwayBrowser/#/R-CEL-9009817 Acitretin binds to RAR:RXR IEA Caenorhabditis elegans A0A131MBD0 R-CEL-2466068 https://reactome.org/PathwayBrowser/#/R-CEL-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Caenorhabditis elegans A0A131MBD0 R-CEL-2468039 https://reactome.org/PathwayBrowser/#/R-CEL-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Caenorhabditis elegans A0A131MBD0 R-CEL-2468040 https://reactome.org/PathwayBrowser/#/R-CEL-2468040 Cohesin binds PDS5 and WAPAL IEA Caenorhabditis elegans A0A131MBD0 R-CEL-2468293 https://reactome.org/PathwayBrowser/#/R-CEL-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Caenorhabditis elegans A0A131MBD0 R-CEL-2470935 https://reactome.org/PathwayBrowser/#/R-CEL-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Caenorhabditis elegans A0A131MBD0 R-CEL-2473152 https://reactome.org/PathwayBrowser/#/R-CEL-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Caenorhabditis elegans A0A131MBD0 R-CEL-3108212 https://reactome.org/PathwayBrowser/#/R-CEL-3108212 SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 IEA Caenorhabditis elegans A0A131MBF9 R-CEL-450394 https://reactome.org/PathwayBrowser/#/R-CEL-450394 p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta IEA Caenorhabditis elegans A0A131MBF9 R-CEL-450400 https://reactome.org/PathwayBrowser/#/R-CEL-450400 ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs IEA Caenorhabditis elegans A0A131MBF9 R-CEL-450431 https://reactome.org/PathwayBrowser/#/R-CEL-450431 ZFP36 (TTP) recruits RNA degradation activities IEA Caenorhabditis elegans A0A131MBF9 R-CEL-450463 https://reactome.org/PathwayBrowser/#/R-CEL-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Caenorhabditis elegans A0A131MBF9 R-CEL-5624948 https://reactome.org/PathwayBrowser/#/R-CEL-5624948 KIF17 enters the cilium IEA Caenorhabditis elegans A0A131MBF9 R-CEL-5624951 https://reactome.org/PathwayBrowser/#/R-CEL-5624951 TNPO1 binds KIF17 dimer IEA Caenorhabditis elegans A0A131MBL3 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans A0A131MBQ7 R-CEL-382096 https://reactome.org/PathwayBrowser/#/R-CEL-382096 Formation of NR-NCOR Corepressor Complex IEA Caenorhabditis elegans A0A131MBQ7 R-CEL-5334854 https://reactome.org/PathwayBrowser/#/R-CEL-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Caenorhabditis elegans A0A131MBQ7 R-CEL-5634103 https://reactome.org/PathwayBrowser/#/R-CEL-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Caenorhabditis elegans A0A131MBQ7 R-CEL-9009817 https://reactome.org/PathwayBrowser/#/R-CEL-9009817 Acitretin binds to RAR:RXR IEA Caenorhabditis elegans A0A131MBT2 R-CEL-3222593 https://reactome.org/PathwayBrowser/#/R-CEL-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Caenorhabditis elegans A0A131MBT2 R-CEL-4754187 https://reactome.org/PathwayBrowser/#/R-CEL-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Caenorhabditis elegans A0A131MBT2 R-CEL-5661121 https://reactome.org/PathwayBrowser/#/R-CEL-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Caenorhabditis elegans A0A131MBT2 R-CEL-8979071 https://reactome.org/PathwayBrowser/#/R-CEL-8979071 KDM6B binds iron IEA Caenorhabditis elegans A0A131MBV2 R-CEL-109530 https://reactome.org/PathwayBrowser/#/R-CEL-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Caenorhabditis elegans A0A131MBV2 R-CEL-109538 https://reactome.org/PathwayBrowser/#/R-CEL-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Caenorhabditis elegans A0A131MBV2 R-CEL-109539 https://reactome.org/PathwayBrowser/#/R-CEL-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Caenorhabditis elegans A0A131MBV2 R-CEL-9751037 https://reactome.org/PathwayBrowser/#/R-CEL-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans A0A131MBV2 R-CEL-9754934 https://reactome.org/PathwayBrowser/#/R-CEL-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans A0A131MCS3 R-CEL-2022368 https://reactome.org/PathwayBrowser/#/R-CEL-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Caenorhabditis elegans A0A131MCS3 R-CEL-2022396 https://reactome.org/PathwayBrowser/#/R-CEL-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Caenorhabditis elegans A0A131MCS3 R-CEL-6798743 https://reactome.org/PathwayBrowser/#/R-CEL-6798743 Exocytosis of secretory granule membrane proteins IEA Caenorhabditis elegans A0A131MCS3 R-CEL-9727607 https://reactome.org/PathwayBrowser/#/R-CEL-9727607 MME:Zn2+ binds sacubitrilat IEA Caenorhabditis elegans A0A131MD13 R-CEL-3222593 https://reactome.org/PathwayBrowser/#/R-CEL-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Caenorhabditis elegans A0A131MD13 R-CEL-4754187 https://reactome.org/PathwayBrowser/#/R-CEL-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Caenorhabditis elegans A0A131MD13 R-CEL-5661121 https://reactome.org/PathwayBrowser/#/R-CEL-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Caenorhabditis elegans A0A131MD13 R-CEL-8979071 https://reactome.org/PathwayBrowser/#/R-CEL-8979071 KDM6B binds iron IEA Caenorhabditis elegans A0A131MD37 R-CEL-8877475 https://reactome.org/PathwayBrowser/#/R-CEL-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Caenorhabditis elegans A0A131MD44 R-CEL-1363303 https://reactome.org/PathwayBrowser/#/R-CEL-1363303 p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 IEA Caenorhabditis elegans A0A131MD44 R-CEL-1363306 https://reactome.org/PathwayBrowser/#/R-CEL-1363306 p130 (RBL2) binds Cyclin E/A:CDK2 IEA Caenorhabditis elegans A0A131MD44 R-CEL-1363311 https://reactome.org/PathwayBrowser/#/R-CEL-1363311 p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 IEA Caenorhabditis elegans A0A131MD44 R-CEL-1363314 https://reactome.org/PathwayBrowser/#/R-CEL-1363314 p107 (RBL1) binds CyclinE/A:CDK2 IEA Caenorhabditis elegans A0A131MD44 R-CEL-170088 https://reactome.org/PathwayBrowser/#/R-CEL-170088 Translocation of CCNA:p-T14-CDK1 to the nucleus IEA Caenorhabditis elegans A0A131MD44 R-CEL-170116 https://reactome.org/PathwayBrowser/#/R-CEL-170116 PKMYT1 phosphorylates CCNA:CDK1 IEA Caenorhabditis elegans A0A131MD44 R-CEL-170158 https://reactome.org/PathwayBrowser/#/R-CEL-170158 CDC25A dephosphorylates CCNA:CDK1 IEA Caenorhabditis elegans A0A131MD44 R-CEL-174054 https://reactome.org/PathwayBrowser/#/R-CEL-174054 Formation of Cyclin A:Cdk2 complexes IEA Caenorhabditis elegans A0A131MD44 R-CEL-174110 https://reactome.org/PathwayBrowser/#/R-CEL-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Caenorhabditis elegans A0A131MD44 R-CEL-174273 https://reactome.org/PathwayBrowser/#/R-CEL-174273 Translocation of Cyclin A:Cdk2 complexes to the nucleus IEA Caenorhabditis elegans A0A131MD44 R-CEL-187520 https://reactome.org/PathwayBrowser/#/R-CEL-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Caenorhabditis elegans A0A131MD44 R-CEL-187552 https://reactome.org/PathwayBrowser/#/R-CEL-187552 Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex IEA Caenorhabditis elegans A0A131MD44 R-CEL-187574 https://reactome.org/PathwayBrowser/#/R-CEL-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Caenorhabditis elegans A0A131MD44 R-CEL-187575 https://reactome.org/PathwayBrowser/#/R-CEL-187575 Ubiquitination of phospho-p27/p21 IEA Caenorhabditis elegans A0A131MD44 R-CEL-187916 https://reactome.org/PathwayBrowser/#/R-CEL-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Caenorhabditis elegans A0A131MD44 R-CEL-187934 https://reactome.org/PathwayBrowser/#/R-CEL-187934 Inactivation of Cyclin A:Cdk2 complexes by p27/p21 IEA Caenorhabditis elegans A0A131MD44 R-CEL-5697009 https://reactome.org/PathwayBrowser/#/R-CEL-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Caenorhabditis elegans A0A131MD44 R-CEL-68944 https://reactome.org/PathwayBrowser/#/R-CEL-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Caenorhabditis elegans A0A131MD44 R-CEL-69005 https://reactome.org/PathwayBrowser/#/R-CEL-69005 Cdc6 protein is phosphorylated by CDK IEA Caenorhabditis elegans A0A131MD44 R-CEL-9928875 https://reactome.org/PathwayBrowser/#/R-CEL-9928875 Formation of CCNA1:CDK1 complex IEA Caenorhabditis elegans A0A131MD44 R-CEL-9929514 https://reactome.org/PathwayBrowser/#/R-CEL-9929514 CDK1 phosphorylates CCNA IEA Caenorhabditis elegans A0A131MD44 R-CEL-9929532 https://reactome.org/PathwayBrowser/#/R-CEL-9929532 CCNA:CDK1 phosphorylates BORA IEA Caenorhabditis elegans A0A131MD44 R-CEL-9929533 https://reactome.org/PathwayBrowser/#/R-CEL-9929533 CCNA:CDK1 complex translocates to the cytosol IEA Caenorhabditis elegans A0A131MD44 R-CEL-9929904 https://reactome.org/PathwayBrowser/#/R-CEL-9929904 CCNA:CDK1 phosphorylates MIS18BP1 IEA Caenorhabditis elegans A0A131MD44 R-CEL-9929935 https://reactome.org/PathwayBrowser/#/R-CEL-9929935 CCNA:CDK1 phosphorylates CDC25B IEA Caenorhabditis elegans A0A140LHZ9 R-MMU-1236398 https://reactome.org/PathwayBrowser/#/R-MMU-1236398 ERBB4 binds NRGs or EGF-like ligands IEA Mus musculus A0A140LHZ9 R-MMU-1247497 https://reactome.org/PathwayBrowser/#/R-MMU-1247497 ERBB3 binds neuregulins IEA Mus musculus A0A140LHZ9 R-MMU-1250189 https://reactome.org/PathwayBrowser/#/R-MMU-1250189 Binding of PI3K to ERBB2:p-ERBB3 heterodimer IEA Mus musculus A0A140LHZ9 R-MMU-1250195 https://reactome.org/PathwayBrowser/#/R-MMU-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Mus musculus A0A140LHZ9 R-MMU-1250220 https://reactome.org/PathwayBrowser/#/R-MMU-1250220 Homodimerization of ERBB4 IEA Mus musculus A0A140LHZ9 R-MMU-1250315 https://reactome.org/PathwayBrowser/#/R-MMU-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Mus musculus A0A140LHZ9 R-MMU-1250346 https://reactome.org/PathwayBrowser/#/R-MMU-1250346 Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers IEA Mus musculus A0A140LHZ9 R-MMU-1250348 https://reactome.org/PathwayBrowser/#/R-MMU-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Mus musculus A0A140LHZ9 R-MMU-1250353 https://reactome.org/PathwayBrowser/#/R-MMU-1250353 Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers IEA Mus musculus A0A140LHZ9 R-MMU-1250357 https://reactome.org/PathwayBrowser/#/R-MMU-1250357 SHC1 binds P-ERBB4 isoform dimers IEA Mus musculus A0A140LHZ9 R-MMU-1250370 https://reactome.org/PathwayBrowser/#/R-MMU-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Mus musculus A0A140LHZ9 R-MMU-1250380 https://reactome.org/PathwayBrowser/#/R-MMU-1250380 Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers IEA Mus musculus A0A140LHZ9 R-MMU-1250383 https://reactome.org/PathwayBrowser/#/R-MMU-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Mus musculus A0A140LHZ9 R-MMU-1250462 https://reactome.org/PathwayBrowser/#/R-MMU-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Mus musculus A0A140LHZ9 R-MMU-1306953 https://reactome.org/PathwayBrowser/#/R-MMU-1306953 GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 IEA Mus musculus A0A140LHZ9 R-MMU-1306969 https://reactome.org/PathwayBrowser/#/R-MMU-1306969 GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers IEA Mus musculus A0A140LHZ9 R-MMU-1306972 https://reactome.org/PathwayBrowser/#/R-MMU-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Mus musculus A0A140LHZ9 R-MMU-1306979 https://reactome.org/PathwayBrowser/#/R-MMU-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Mus musculus A0A140LHZ9 R-MMU-1358792 https://reactome.org/PathwayBrowser/#/R-MMU-1358792 RNF41 ubiquitinates activated ERBB3 IEA Mus musculus A0A140LHZ9 R-MMU-1358798 https://reactome.org/PathwayBrowser/#/R-MMU-1358798 RNF41 binds neuregulin-activated ERBB3 IEA Mus musculus A0A140LHZ9 R-MMU-1963563 https://reactome.org/PathwayBrowser/#/R-MMU-1963563 MATK (CSK homologous kinase) binds phosphorylated ERBB2 IEA Mus musculus A0A140LHZ9 R-MMU-1963581 https://reactome.org/PathwayBrowser/#/R-MMU-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Mus musculus A0A140LHZ9 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus A0A140LHZ9 R-MMU-1963586 https://reactome.org/PathwayBrowser/#/R-MMU-1963586 SRC family kinases phosphorylate ERBB2 IEA Mus musculus A0A140LHZ9 R-MMU-1963589 https://reactome.org/PathwayBrowser/#/R-MMU-1963589 ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 IEA Mus musculus A0A140LHZ9 R-MMU-1977958 https://reactome.org/PathwayBrowser/#/R-MMU-1977958 ERBB4 forms heterodimers with ERBB3 IEA Mus musculus A0A140LHZ9 R-MMU-1977959 https://reactome.org/PathwayBrowser/#/R-MMU-1977959 ERBB4 forms heterodimers with EGFR IEA Mus musculus A0A140LHZ9 R-MMU-2316434 https://reactome.org/PathwayBrowser/#/R-MMU-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A140LHZ9 R-MMU-5672965 https://reactome.org/PathwayBrowser/#/R-MMU-5672965 RAS GEFs promote RAS nucleotide exchange IEA Mus musculus A0A140LHZ9 R-MMU-6785636 https://reactome.org/PathwayBrowser/#/R-MMU-6785636 Phosphorylated ERBB2 heterodimers bind MEMO1 IEA Mus musculus A0A140LHZ9 R-MMU-6785648 https://reactome.org/PathwayBrowser/#/R-MMU-6785648 MEMO1 binds RHOA:GTP:DIAPH1 IEA Mus musculus A0A140LHZ9 R-MMU-8847995 https://reactome.org/PathwayBrowser/#/R-MMU-8847995 Activated ERBB2 binds PTK6 (BRK) IEA Mus musculus A0A140LHZ9 R-MMU-8848005 https://reactome.org/PathwayBrowser/#/R-MMU-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Mus musculus A0A140LHZ9 R-MMU-8863804 https://reactome.org/PathwayBrowser/#/R-MMU-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Mus musculus A0A140LIW3 R-MMU-6798743 https://reactome.org/PathwayBrowser/#/R-MMU-6798743 Exocytosis of secretory granule membrane proteins IEA Mus musculus A0A140LIW3 R-MMU-6798747 https://reactome.org/PathwayBrowser/#/R-MMU-6798747 Exocytosis of tertiary granule membrane proteins IEA Mus musculus A0A140LJ72 R-MMU-1964501 https://reactome.org/PathwayBrowser/#/R-MMU-1964501 Addition of galactose to Core 6 glycoprotein IEA Mus musculus A0A140LJ72 R-MMU-1964505 https://reactome.org/PathwayBrowser/#/R-MMU-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Mus musculus A0A140LJ72 R-MMU-5694487 https://reactome.org/PathwayBrowser/#/R-MMU-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Mus musculus A0A140LJ72 R-MMU-6786012 https://reactome.org/PathwayBrowser/#/R-MMU-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Mus musculus A0A140LJ72 R-MMU-913675 https://reactome.org/PathwayBrowser/#/R-MMU-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Mus musculus A0A140LJ72 R-MMU-914005 https://reactome.org/PathwayBrowser/#/R-MMU-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Mus musculus A0A140LJ72 R-MMU-914006 https://reactome.org/PathwayBrowser/#/R-MMU-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Mus musculus A0A140LJ72 R-MMU-914008 https://reactome.org/PathwayBrowser/#/R-MMU-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Mus musculus A0A140LJ72 R-MMU-914010 https://reactome.org/PathwayBrowser/#/R-MMU-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Mus musculus A0A140LJ72 R-MMU-914012 https://reactome.org/PathwayBrowser/#/R-MMU-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Mus musculus A0A140LJ72 R-MMU-914017 https://reactome.org/PathwayBrowser/#/R-MMU-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Mus musculus A0A140LJ72 R-MMU-914018 https://reactome.org/PathwayBrowser/#/R-MMU-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Mus musculus A0A140LJ72 R-MMU-977071 https://reactome.org/PathwayBrowser/#/R-MMU-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Mus musculus A0A140LJ72 R-MMU-981497 https://reactome.org/PathwayBrowser/#/R-MMU-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Mus musculus A0A140LJ72 R-MMU-981809 https://reactome.org/PathwayBrowser/#/R-MMU-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Mus musculus A0A140LJ72 R-MMU-981814 https://reactome.org/PathwayBrowser/#/R-MMU-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Mus musculus A0A140T828 R-BTA-1592387 https://reactome.org/PathwayBrowser/#/R-BTA-1592387 Fibulin binds elastic fibres IEA Bos taurus A0A140T828 R-BTA-2129353 https://reactome.org/PathwayBrowser/#/R-BTA-2129353 Tropoelastin associates with microfibrils IEA Bos taurus A0A140T828 R-BTA-2129375 https://reactome.org/PathwayBrowser/#/R-BTA-2129375 Elastin cross-linking by lysyl oxidase IEA Bos taurus A0A140T828 R-BTA-2129385 https://reactome.org/PathwayBrowser/#/R-BTA-2129385 MFAP2, MFAP5 bind microfibrils IEA Bos taurus A0A140T828 R-BTA-2161282 https://reactome.org/PathwayBrowser/#/R-BTA-2161282 Elastic fibres bind associated proteins IEA Bos taurus A0A140T831 R-BTA-6798745 https://reactome.org/PathwayBrowser/#/R-BTA-6798745 Exocytosis of tertiary granule lumen proteins IEA Bos taurus A0A140T831 R-BTA-6798748 https://reactome.org/PathwayBrowser/#/R-BTA-6798748 Exocytosis of secretory granule lumen proteins IEA Bos taurus A0A140T831 R-BTA-6800434 https://reactome.org/PathwayBrowser/#/R-BTA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Bos taurus A0A140T832 R-BTA-156808 https://reactome.org/PathwayBrowser/#/R-BTA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Bos taurus A0A140T832 R-BTA-156823 https://reactome.org/PathwayBrowser/#/R-BTA-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Bos taurus A0A140T832 R-BTA-157849 https://reactome.org/PathwayBrowser/#/R-BTA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Bos taurus A0A140T832 R-BTA-1799332 https://reactome.org/PathwayBrowser/#/R-BTA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Bos taurus A0A140T832 R-BTA-6791223 https://reactome.org/PathwayBrowser/#/R-BTA-6791223 18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol IEA Bos taurus A0A140T832 R-BTA-72621 https://reactome.org/PathwayBrowser/#/R-BTA-72621 Ribosomal scanning IEA Bos taurus A0A140T832 R-BTA-72671 https://reactome.org/PathwayBrowser/#/R-BTA-72671 eIF5B:GTP is hydrolyzed and released IEA Bos taurus A0A140T832 R-BTA-72672 https://reactome.org/PathwayBrowser/#/R-BTA-72672 The 60S subunit joins the translation initiation complex IEA Bos taurus A0A140T832 R-BTA-72673 https://reactome.org/PathwayBrowser/#/R-BTA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Bos taurus A0A140T832 R-BTA-72676 https://reactome.org/PathwayBrowser/#/R-BTA-72676 eIF3 and eIF1A bind to the 40S subunit IEA Bos taurus A0A140T832 R-BTA-72691 https://reactome.org/PathwayBrowser/#/R-BTA-72691 Formation of the 43S pre-initiation complex IEA Bos taurus A0A140T832 R-BTA-72697 https://reactome.org/PathwayBrowser/#/R-BTA-72697 Start codon recognition IEA Bos taurus A0A140T832 R-BTA-927789 https://reactome.org/PathwayBrowser/#/R-BTA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Bos taurus A0A140T832 R-BTA-927813 https://reactome.org/PathwayBrowser/#/R-BTA-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Bos taurus A0A140T832 R-BTA-927832 https://reactome.org/PathwayBrowser/#/R-BTA-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Bos taurus A0A140T832 R-BTA-927836 https://reactome.org/PathwayBrowser/#/R-BTA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Bos taurus A0A140T832 R-BTA-927889 https://reactome.org/PathwayBrowser/#/R-BTA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Bos taurus A0A140T837 R-BTA-141200 https://reactome.org/PathwayBrowser/#/R-BTA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Bos taurus A0A140T837 R-BTA-141202 https://reactome.org/PathwayBrowser/#/R-BTA-141202 MAOB:FAD oxidatively deaminates TYR IEA Bos taurus A0A140T837 R-BTA-9677929 https://reactome.org/PathwayBrowser/#/R-BTA-9677929 MAOB inhibitors bind MAOB:FAD IEA Bos taurus A0A140T838 R-BTA-445752 https://reactome.org/PathwayBrowser/#/R-BTA-445752 Interleukin-1 receptor type 1: Interleukin 1 binds Interleukin-1 receptor accessory protein, membrane associated isoform IEA Bos taurus A0A140T838 R-BTA-445753 https://reactome.org/PathwayBrowser/#/R-BTA-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Bos taurus A0A140T838 R-BTA-446130 https://reactome.org/PathwayBrowser/#/R-BTA-446130 Interleukin-1 receptor type 2 binds Interleukin 1 IEA Bos taurus A0A140T838 R-BTA-446634 https://reactome.org/PathwayBrowser/#/R-BTA-446634 IRAK4 is activated by autophosphorylation IEA Bos taurus A0A140T838 R-BTA-446648 https://reactome.org/PathwayBrowser/#/R-BTA-446648 IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 IEA Bos taurus A0A140T838 R-BTA-446684 https://reactome.org/PathwayBrowser/#/R-BTA-446684 IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation IEA Bos taurus A0A140T838 R-BTA-446692 https://reactome.org/PathwayBrowser/#/R-BTA-446692 IRAK1 binds to MYD88 within the IL1R complex IEA Bos taurus A0A140T838 R-BTA-446694 https://reactome.org/PathwayBrowser/#/R-BTA-446694 IRAK4 phosphorylates IRAK1 IEA Bos taurus A0A140T838 R-BTA-446701 https://reactome.org/PathwayBrowser/#/R-BTA-446701 IRAK4-activated IRAK1 autophosphorylates IEA Bos taurus A0A140T838 R-BTA-446862 https://reactome.org/PathwayBrowser/#/R-BTA-446862 Hyperphosphorylated IRAK1 associates with TRAF6 IEA Bos taurus A0A140T838 R-BTA-446868 https://reactome.org/PathwayBrowser/#/R-BTA-446868 The Interleukin 1 receptor complex binds Tollip IEA Bos taurus A0A140T838 R-BTA-446894 https://reactome.org/PathwayBrowser/#/R-BTA-446894 TRAF6 binding leads to IRAK1:TRAF6 release IEA Bos taurus A0A140T838 R-BTA-448703 https://reactome.org/PathwayBrowser/#/R-BTA-448703 Interleukin-1 family precursors are cleaved by caspase-1 IEA Bos taurus A0A140T838 R-BTA-449058 https://reactome.org/PathwayBrowser/#/R-BTA-449058 Interleukin-1 family are secreted IEA Bos taurus A0A140T838 R-BTA-450133 https://reactome.org/PathwayBrowser/#/R-BTA-450133 IL1R1:IL1:IL1RAP binds MYD88 homodimer IEA Bos taurus A0A140T838 R-BTA-507719 https://reactome.org/PathwayBrowser/#/R-BTA-507719 p62:MEKK3 binds to TRAF6 IEA Bos taurus A0A140T838 R-BTA-5660663 https://reactome.org/PathwayBrowser/#/R-BTA-5660663 Caspase-8 cleaves IL1B precursor IEA Bos taurus A0A140T842 R-BTA-9837978 https://reactome.org/PathwayBrowser/#/R-BTA-9837978 LONP1 binds mitochondrial inner membrane proteins IEA Bos taurus A0A140T842 R-BTA-9838004 https://reactome.org/PathwayBrowser/#/R-BTA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Bos taurus A0A140T842 R-BTA-9838081 https://reactome.org/PathwayBrowser/#/R-BTA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Bos taurus A0A140T842 R-BTA-9838093 https://reactome.org/PathwayBrowser/#/R-BTA-9838093 LONP1 binds mitochondrial matrix proteins IEA Bos taurus A0A140T843 R-BTA-481009 https://reactome.org/PathwayBrowser/#/R-BTA-481009 Exocytosis of platelet dense granule content IEA Bos taurus A0A140T846 R-BTA-110350 https://reactome.org/PathwayBrowser/#/R-BTA-110350 Displacement of TDG glycosylase by APEX1 at the AP site IEA Bos taurus A0A140T846 R-BTA-110351 https://reactome.org/PathwayBrowser/#/R-BTA-110351 Displacement of SMUG1 glycosylase by APEX1 at the AP site IEA Bos taurus A0A140T846 R-BTA-110352 https://reactome.org/PathwayBrowser/#/R-BTA-110352 Displacement of NTHL1 glycosylase by APEX1 at the AP site IEA Bos taurus A0A140T846 R-BTA-110353 https://reactome.org/PathwayBrowser/#/R-BTA-110353 Displacement of MBD4 glycosylase by APEX1 at the AP site IEA Bos taurus A0A140T846 R-BTA-110354 https://reactome.org/PathwayBrowser/#/R-BTA-110354 Displacement of OGG1 glycosylase by APEX1 at the AP site IEA Bos taurus A0A140T846 R-BTA-110355 https://reactome.org/PathwayBrowser/#/R-BTA-110355 Displacement of MUTYH glycosylase by APEX1 at the AP site IEA Bos taurus A0A140T846 R-BTA-110356 https://reactome.org/PathwayBrowser/#/R-BTA-110356 Displacement of MPG glycosylase by APEX1 at the AP site IEA Bos taurus A0A140T846 R-BTA-110359 https://reactome.org/PathwayBrowser/#/R-BTA-110359 APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site IEA Bos taurus A0A140T846 R-BTA-110360 https://reactome.org/PathwayBrowser/#/R-BTA-110360 Recruitment of POLB to the AP site IEA Bos taurus A0A140T846 R-BTA-110364 https://reactome.org/PathwayBrowser/#/R-BTA-110364 PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 IEA Bos taurus A0A140T846 R-BTA-110368 https://reactome.org/PathwayBrowser/#/R-BTA-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Bos taurus A0A140T846 R-BTA-110371 https://reactome.org/PathwayBrowser/#/R-BTA-110371 LIG1 binds APEX1 and PCNA at SSB IEA Bos taurus A0A140T846 R-BTA-110375 https://reactome.org/PathwayBrowser/#/R-BTA-110375 Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break IEA Bos taurus A0A140T846 R-BTA-111253 https://reactome.org/PathwayBrowser/#/R-BTA-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Bos taurus A0A140T846 R-BTA-5649854 https://reactome.org/PathwayBrowser/#/R-BTA-5649854 Recruitment of POLB to oxidatively damaged AP site IEA Bos taurus A0A140T846 R-BTA-5649856 https://reactome.org/PathwayBrowser/#/R-BTA-5649856 Oxidative damage to the AP site IEA Bos taurus A0A140T846 R-BTA-5649873 https://reactome.org/PathwayBrowser/#/R-BTA-5649873 PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site IEA Bos taurus A0A140T846 R-BTA-5651805 https://reactome.org/PathwayBrowser/#/R-BTA-5651805 LIG1 bound to APEX1 and PCNA ligates SSB IEA Bos taurus A0A140T847 R-BTA-3247837 https://reactome.org/PathwayBrowser/#/R-BTA-3247837 WNT ligands traffic to the Golgi IEA Bos taurus A0A140T847 R-BTA-3247840 https://reactome.org/PathwayBrowser/#/R-BTA-3247840 WLS binds WNT ligands in the Golgi IEA Bos taurus A0A140T847 R-BTA-3247843 https://reactome.org/PathwayBrowser/#/R-BTA-3247843 secretion of WNT ligands IEA Bos taurus A0A140T847 R-BTA-3247844 https://reactome.org/PathwayBrowser/#/R-BTA-3247844 WNT ligands traffic to the plasma membrane IEA Bos taurus A0A140T847 R-BTA-3781941 https://reactome.org/PathwayBrowser/#/R-BTA-3781941 WNTs are secreted in exosomes IEA Bos taurus A0A140T847 R-BTA-3781943 https://reactome.org/PathwayBrowser/#/R-BTA-3781943 WLS:WNT complex is internalized for maturation into exosomes IEA Bos taurus A0A140T850 R-BTA-174394 https://reactome.org/PathwayBrowser/#/R-BTA-174394 GSS:Mg2+ dimer synthesizes GSH IEA Bos taurus A0A140T852 R-BTA-5419261 https://reactome.org/PathwayBrowser/#/R-BTA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Bos taurus A0A140T852 R-BTA-5419264 https://reactome.org/PathwayBrowser/#/R-BTA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Bos taurus A0A140T852 R-BTA-5419271 https://reactome.org/PathwayBrowser/#/R-BTA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Bos taurus A0A140T852 R-BTA-5419273 https://reactome.org/PathwayBrowser/#/R-BTA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Bos taurus A0A140T852 R-BTA-5419281 https://reactome.org/PathwayBrowser/#/R-BTA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Bos taurus A0A140T853 R-BTA-191382 https://reactome.org/PathwayBrowser/#/R-BTA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Bos taurus A0A140T856 R-BTA-6807872 https://reactome.org/PathwayBrowser/#/R-BTA-6807872 Active ARF recruits coatomer IEA Bos taurus A0A140T856 R-BTA-6807877 https://reactome.org/PathwayBrowser/#/R-BTA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Bos taurus A0A140T856 R-BTA-6809003 https://reactome.org/PathwayBrowser/#/R-BTA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Bos taurus A0A140T856 R-BTA-6809006 https://reactome.org/PathwayBrowser/#/R-BTA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Bos taurus A0A140T856 R-BTA-6809011 https://reactome.org/PathwayBrowser/#/R-BTA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Bos taurus A0A140T856 R-BTA-6811412 https://reactome.org/PathwayBrowser/#/R-BTA-6811412 Active ARF recruits coatomer to the Golgi IEA Bos taurus A0A140T856 R-BTA-6811417 https://reactome.org/PathwayBrowser/#/R-BTA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Bos taurus A0A140T856 R-BTA-6811418 https://reactome.org/PathwayBrowser/#/R-BTA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Bos taurus A0A140T856 R-BTA-6811423 https://reactome.org/PathwayBrowser/#/R-BTA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Bos taurus A0A140T856 R-BTA-6811426 https://reactome.org/PathwayBrowser/#/R-BTA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Bos taurus A0A140T856 R-BTA-6811427 https://reactome.org/PathwayBrowser/#/R-BTA-6811427 COPI vesicle uncoating at the ER IEA Bos taurus A0A140T857 R-BTA-163214 https://reactome.org/PathwayBrowser/#/R-BTA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Bos taurus A0A140T857 R-BTA-9709406 https://reactome.org/PathwayBrowser/#/R-BTA-9709406 CO binds to Cytochrome c oxidase IEA Bos taurus A0A140T857 R-BTA-9865663 https://reactome.org/PathwayBrowser/#/R-BTA-9865663 MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex IEA Bos taurus A0A140T858 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus A0A140T858 R-BTA-388529 https://reactome.org/PathwayBrowser/#/R-BTA-388529 Cholecystokinin receptors bind cholecystokinin IEA Bos taurus A0A140T858 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus A0A140T858 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus A0A140T858 R-BTA-870269 https://reactome.org/PathwayBrowser/#/R-BTA-870269 Gastrin binds to CCK-B receptor IEA Bos taurus A0A140T859 R-BTA-170055 https://reactome.org/PathwayBrowser/#/R-BTA-170055 Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes IEA Bos taurus A0A140T859 R-BTA-170057 https://reactome.org/PathwayBrowser/#/R-BTA-170057 Formation of Cyclin B:Cdc2 complexes IEA Bos taurus A0A140T859 R-BTA-170161 https://reactome.org/PathwayBrowser/#/R-BTA-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Bos taurus A0A140T859 R-BTA-2468287 https://reactome.org/PathwayBrowser/#/R-BTA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Bos taurus A0A140T859 R-BTA-2468293 https://reactome.org/PathwayBrowser/#/R-BTA-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Bos taurus A0A140T859 R-BTA-2984220 https://reactome.org/PathwayBrowser/#/R-BTA-2984220 CDK1:CCNB phosphorylates NEK9 IEA Bos taurus A0A140T859 R-BTA-2990882 https://reactome.org/PathwayBrowser/#/R-BTA-2990882 CDK1 phosphorylates NUP98 IEA Bos taurus A0A140T859 R-BTA-4086410 https://reactome.org/PathwayBrowser/#/R-BTA-4086410 CCNB:CDK1 phosphorylates BORA IEA Bos taurus A0A140T859 R-BTA-8852306 https://reactome.org/PathwayBrowser/#/R-BTA-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Bos taurus A0A140T859 R-BTA-9624800 https://reactome.org/PathwayBrowser/#/R-BTA-9624800 CDK1 phosphorylates LBR IEA Bos taurus A0A140T861 R-BTA-72103 https://reactome.org/PathwayBrowser/#/R-BTA-72103 Formation of pre-mRNPs IEA Bos taurus A0A140T861 R-BTA-9770119 https://reactome.org/PathwayBrowser/#/R-BTA-9770119 Formation of the Spliceosomal E complex IEA Bos taurus A0A140T861 R-BTA-9770141 https://reactome.org/PathwayBrowser/#/R-BTA-9770141 Formation of the Spliceosomal C* complex IEA Bos taurus A0A140T861 R-BTA-9770145 https://reactome.org/PathwayBrowser/#/R-BTA-9770145 Formation of the Spliceosomal Bact complex IEA Bos taurus A0A140T861 R-BTA-9770236 https://reactome.org/PathwayBrowser/#/R-BTA-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Bos taurus A0A140T861 R-BTA-9794542 https://reactome.org/PathwayBrowser/#/R-BTA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Bos taurus A0A140T863 R-BTA-9770145 https://reactome.org/PathwayBrowser/#/R-BTA-9770145 Formation of the Spliceosomal Bact complex IEA Bos taurus A0A140T866 R-BTA-977348 https://reactome.org/PathwayBrowser/#/R-BTA-977348 PHGDH tetramer dehydrogenates 3PG IEA Bos taurus A0A140T869 R-BTA-2430535 https://reactome.org/PathwayBrowser/#/R-BTA-2430535 MASTL phosphorylates ENSA IEA Bos taurus A0A140T871 R-BTA-5688276 https://reactome.org/PathwayBrowser/#/R-BTA-5688276 SIRT4 transfers ADPRib to GLUD IEA Bos taurus A0A140T871 R-BTA-5688289 https://reactome.org/PathwayBrowser/#/R-BTA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Bos taurus A0A140T871 R-BTA-70589 https://reactome.org/PathwayBrowser/#/R-BTA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Bos taurus A0A140T871 R-BTA-70600 https://reactome.org/PathwayBrowser/#/R-BTA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Bos taurus A0A140T871 R-BTA-9838081 https://reactome.org/PathwayBrowser/#/R-BTA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Bos taurus A0A140T871 R-BTA-9838093 https://reactome.org/PathwayBrowser/#/R-BTA-9838093 LONP1 binds mitochondrial matrix proteins IEA Bos taurus A0A140T872 R-BTA-197963 https://reactome.org/PathwayBrowser/#/R-BTA-197963 DHFR2 reduces FOLA to DHF IEA Bos taurus A0A140T872 R-BTA-197972 https://reactome.org/PathwayBrowser/#/R-BTA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Bos taurus A0A140T872 R-BTA-9709098 https://reactome.org/PathwayBrowser/#/R-BTA-9709098 DHFR dimer reduces FOLA to DHF IEA Bos taurus A0A140T872 R-BTA-9709109 https://reactome.org/PathwayBrowser/#/R-BTA-9709109 DHFR dimer binds DHFR inhibitors IEA Bos taurus A0A140T874 R-BTA-5696101 https://reactome.org/PathwayBrowser/#/R-BTA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Bos taurus A0A140T878 R-BTA-1295540 https://reactome.org/PathwayBrowser/#/R-BTA-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 IEA Bos taurus A0A140T878 R-BTA-1433456 https://reactome.org/PathwayBrowser/#/R-BTA-1433456 Recruitment of STATs IEA Bos taurus A0A140T878 R-BTA-1470009 https://reactome.org/PathwayBrowser/#/R-BTA-1470009 Phosphorylation of STATs IEA Bos taurus A0A140T878 R-BTA-1470010 https://reactome.org/PathwayBrowser/#/R-BTA-1470010 Dimerization of STATs IEA Bos taurus A0A140T878 R-BTA-1470012 https://reactome.org/PathwayBrowser/#/R-BTA-1470012 Disassociation and translocation of STATs to the nucleus IEA Bos taurus A0A140T878 R-BTA-380782 https://reactome.org/PathwayBrowser/#/R-BTA-380782 STAT binds to the active receptor IEA Bos taurus A0A140T878 R-BTA-452097 https://reactome.org/PathwayBrowser/#/R-BTA-452097 Recruited STAT5 is phosphorylated IEA Bos taurus A0A140T878 R-BTA-452108 https://reactome.org/PathwayBrowser/#/R-BTA-452108 Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment IEA Bos taurus A0A140T878 R-BTA-6785165 https://reactome.org/PathwayBrowser/#/R-BTA-6785165 p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B IEA Bos taurus A0A140T878 R-BTA-879909 https://reactome.org/PathwayBrowser/#/R-BTA-879909 Activation of STAT5a/b by JAK2 IEA Bos taurus A0A140T878 R-BTA-879930 https://reactome.org/PathwayBrowser/#/R-BTA-879930 STAT5 is recruited by JAK2 IEA Bos taurus A0A140T878 R-BTA-8983371 https://reactome.org/PathwayBrowser/#/R-BTA-8983371 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 IEA Bos taurus A0A140T878 R-BTA-8983373 https://reactome.org/PathwayBrowser/#/R-BTA-8983373 p-Y-STAT3 binds p-STAT5 IEA Bos taurus A0A140T878 R-BTA-8983374 https://reactome.org/PathwayBrowser/#/R-BTA-8983374 p-Y-STAT3 and p-STAT5 dissociates from IL15:IL15RA:IL2RB:p-JAK1:IL2RG:p-JAK3:p-Y-STAT3:p-STAT5 IEA Bos taurus A0A140T878 R-BTA-8983378 https://reactome.org/PathwayBrowser/#/R-BTA-8983378 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 IEA Bos taurus A0A140T878 R-BTA-8983379 https://reactome.org/PathwayBrowser/#/R-BTA-8983379 p-Y-STAT3:p-STAT5 translocates to the nucleus IEA Bos taurus A0A140T878 R-BTA-8985900 https://reactome.org/PathwayBrowser/#/R-BTA-8985900 p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 IEA Bos taurus A0A140T878 R-BTA-8985929 https://reactome.org/PathwayBrowser/#/R-BTA-8985929 IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B IEA Bos taurus A0A140T878 R-BTA-8985950 https://reactome.org/PathwayBrowser/#/R-BTA-8985950 p-Y694-STAT5A, p-STAT5B dimerizes IEA Bos taurus A0A140T878 R-BTA-8985988 https://reactome.org/PathwayBrowser/#/R-BTA-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Bos taurus A0A140T878 R-BTA-8986985 https://reactome.org/PathwayBrowser/#/R-BTA-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Bos taurus A0A140T878 R-BTA-8987033 https://reactome.org/PathwayBrowser/#/R-BTA-8987033 p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 IEA Bos taurus A0A140T878 R-BTA-8987266 https://reactome.org/PathwayBrowser/#/R-BTA-8987266 IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 IEA Bos taurus A0A140T878 R-BTA-9006870 https://reactome.org/PathwayBrowser/#/R-BTA-9006870 IL21 receptor STAT phosphorylation IEA Bos taurus A0A140T878 R-BTA-9006873 https://reactome.org/PathwayBrowser/#/R-BTA-9006873 IL21 receptor STAT binding IEA Bos taurus A0A140T878 R-BTA-9025969 https://reactome.org/PathwayBrowser/#/R-BTA-9025969 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 binds STAT5 IEA Bos taurus A0A140T878 R-BTA-919404 https://reactome.org/PathwayBrowser/#/R-BTA-919404 Phosphorylated STAT5 is released IEA Bos taurus A0A140T878 R-BTA-921155 https://reactome.org/PathwayBrowser/#/R-BTA-921155 p-STAT5 dissociates from the receptor complex IEA Bos taurus A0A140T881 R-BTA-174657 https://reactome.org/PathwayBrowser/#/R-BTA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Bos taurus A0A140T881 R-BTA-174660 https://reactome.org/PathwayBrowser/#/R-BTA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Bos taurus A0A140T881 R-BTA-174690 https://reactome.org/PathwayBrowser/#/R-BTA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Bos taurus A0A140T881 R-BTA-174706 https://reactome.org/PathwayBrowser/#/R-BTA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Bos taurus A0A140T881 R-BTA-174739 https://reactome.org/PathwayBrowser/#/R-BTA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Bos taurus A0A140T881 R-BTA-174757 https://reactome.org/PathwayBrowser/#/R-BTA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Bos taurus A0A140T881 R-BTA-2395768 https://reactome.org/PathwayBrowser/#/R-BTA-2395768 LPL hydrolyses TGs from mature CMs IEA Bos taurus A0A140T881 R-BTA-2395784 https://reactome.org/PathwayBrowser/#/R-BTA-2395784 Nascent CMs transform into mature CMs IEA Bos taurus A0A140T881 R-BTA-2404131 https://reactome.org/PathwayBrowser/#/R-BTA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Bos taurus A0A140T881 R-BTA-2423785 https://reactome.org/PathwayBrowser/#/R-BTA-2423785 CR:atREs binds apoE and HSPG IEA Bos taurus A0A140T881 R-BTA-266303 https://reactome.org/PathwayBrowser/#/R-BTA-266303 Spherical HDL binds C and E apolipoproteins IEA Bos taurus A0A140T881 R-BTA-8952289 https://reactome.org/PathwayBrowser/#/R-BTA-8952289 FAM20C phosphorylates FAM20C substrates IEA Bos taurus A0A140T885 R-BTA-8952289 https://reactome.org/PathwayBrowser/#/R-BTA-8952289 FAM20C phosphorylates FAM20C substrates IEA Bos taurus A0A140T886 R-BTA-6807872 https://reactome.org/PathwayBrowser/#/R-BTA-6807872 Active ARF recruits coatomer IEA Bos taurus A0A140T886 R-BTA-6807877 https://reactome.org/PathwayBrowser/#/R-BTA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Bos taurus A0A140T886 R-BTA-6809003 https://reactome.org/PathwayBrowser/#/R-BTA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Bos taurus A0A140T886 R-BTA-6809006 https://reactome.org/PathwayBrowser/#/R-BTA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Bos taurus A0A140T886 R-BTA-6809011 https://reactome.org/PathwayBrowser/#/R-BTA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Bos taurus A0A140T886 R-BTA-6811412 https://reactome.org/PathwayBrowser/#/R-BTA-6811412 Active ARF recruits coatomer to the Golgi IEA Bos taurus A0A140T886 R-BTA-6811417 https://reactome.org/PathwayBrowser/#/R-BTA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Bos taurus A0A140T886 R-BTA-6811418 https://reactome.org/PathwayBrowser/#/R-BTA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Bos taurus A0A140T886 R-BTA-6811423 https://reactome.org/PathwayBrowser/#/R-BTA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Bos taurus A0A140T886 R-BTA-6811426 https://reactome.org/PathwayBrowser/#/R-BTA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Bos taurus A0A140T886 R-BTA-6811427 https://reactome.org/PathwayBrowser/#/R-BTA-6811427 COPI vesicle uncoating at the ER IEA Bos taurus A0A140T887 R-BTA-73564 https://reactome.org/PathwayBrowser/#/R-BTA-73564 UMPS dimer decarboxylates OMP to UMP IEA Bos taurus A0A140T887 R-BTA-73567 https://reactome.org/PathwayBrowser/#/R-BTA-73567 UMPS dimer transfers phosphoribosyl group to ORO to form OMP IEA Bos taurus A0A140T888 R-BTA-1675813 https://reactome.org/PathwayBrowser/#/R-BTA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Bos taurus A0A140T888 R-BTA-1676185 https://reactome.org/PathwayBrowser/#/R-BTA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Bos taurus A0A140T890 R-BTA-2025723 https://reactome.org/PathwayBrowser/#/R-BTA-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Bos taurus A0A140T890 R-BTA-2025724 https://reactome.org/PathwayBrowser/#/R-BTA-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Bos taurus A0A140T890 R-BTA-2046175 https://reactome.org/PathwayBrowser/#/R-BTA-2046175 Further sulfation on galactose residues produces KSPG IEA Bos taurus A0A140T890 R-BTA-2046180 https://reactome.org/PathwayBrowser/#/R-BTA-2046180 KSPG is secreted from the cell IEA Bos taurus A0A140T890 R-BTA-2046222 https://reactome.org/PathwayBrowser/#/R-BTA-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Bos taurus A0A140T890 R-BTA-2046239 https://reactome.org/PathwayBrowser/#/R-BTA-2046239 Extracellular KSPG translocates to the lysosome for degradation IEA Bos taurus A0A140T890 R-BTA-2046265 https://reactome.org/PathwayBrowser/#/R-BTA-2046265 B4GALTs transfer Gal to the keratan chain IEA Bos taurus A0A140T890 R-BTA-2046285 https://reactome.org/PathwayBrowser/#/R-BTA-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Bos taurus A0A140T890 R-BTA-2046298 https://reactome.org/PathwayBrowser/#/R-BTA-2046298 B4GALTs transfer Gal to a branch of keratan IEA Bos taurus A0A140T891 R-BTA-6798739 https://reactome.org/PathwayBrowser/#/R-BTA-6798739 Exocytosis of azurophil granule membrane proteins IEA Bos taurus A0A140T891 R-BTA-8938300 https://reactome.org/PathwayBrowser/#/R-BTA-8938300 Vanin hydrolyses pantetheine to PanK, 2AET IEA Bos taurus A0A140T891 R-BTA-8940388 https://reactome.org/PathwayBrowser/#/R-BTA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Bos taurus A0A140T893 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus A0A140T893 R-BTA-391377 https://reactome.org/PathwayBrowser/#/R-BTA-391377 Luteinizing hormone receptor can bind LH IEA Bos taurus A0A140T894 R-BTA-139899 https://reactome.org/PathwayBrowser/#/R-BTA-139899 Sequestration of BAD protein by 14-3-3 IEA Bos taurus A0A140T894 R-BTA-139906 https://reactome.org/PathwayBrowser/#/R-BTA-139906 Activation of BAD by calcineurin IEA Bos taurus A0A140T894 R-BTA-165692 https://reactome.org/PathwayBrowser/#/R-BTA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Bos taurus A0A140T894 R-BTA-165718 https://reactome.org/PathwayBrowser/#/R-BTA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Bos taurus A0A140T894 R-BTA-2028644 https://reactome.org/PathwayBrowser/#/R-BTA-2028644 YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 IEA Bos taurus A0A140T894 R-BTA-392513 https://reactome.org/PathwayBrowser/#/R-BTA-392513 Rap1 signal termination by Rap1GAPs IEA Bos taurus A0A140T894 R-BTA-450394 https://reactome.org/PathwayBrowser/#/R-BTA-450394 p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta IEA Bos taurus A0A140T894 R-BTA-450406 https://reactome.org/PathwayBrowser/#/R-BTA-450406 p-S92,203-BRF1 binds 14-3-3 IEA Bos taurus A0A140T894 R-BTA-482788 https://reactome.org/PathwayBrowser/#/R-BTA-482788 p-S54,92,203-BRF1 binds 14-3-3 IEA Bos taurus A0A140T894 R-BTA-5632732 https://reactome.org/PathwayBrowser/#/R-BTA-5632732 p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 IEA Bos taurus A0A140T894 R-BTA-5632738 https://reactome.org/PathwayBrowser/#/R-BTA-5632738 DDIT4 binds 14-3-3 dimer IEA Bos taurus A0A140T894 R-BTA-5672824 https://reactome.org/PathwayBrowser/#/R-BTA-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Bos taurus A0A140T894 R-BTA-5672828 https://reactome.org/PathwayBrowser/#/R-BTA-5672828 mTORC1 phosphorylates AKT1S1 IEA Bos taurus A0A140T894 R-BTA-5672950 https://reactome.org/PathwayBrowser/#/R-BTA-5672950 "Activator" RAF:YWHAB dimer binds RAS:GTP IEA Bos taurus A0A140T894 R-BTA-5672951 https://reactome.org/PathwayBrowser/#/R-BTA-5672951 Inactive RAFs bind YWHAB IEA Bos taurus A0A140T894 R-BTA-5672954 https://reactome.org/PathwayBrowser/#/R-BTA-5672954 p-S311,S406 KSR1:MARK3 binds YWHAB dimer IEA Bos taurus A0A140T894 R-BTA-5672957 https://reactome.org/PathwayBrowser/#/R-BTA-5672957 PP2A dephosphorylates KSR1 IEA Bos taurus A0A140T894 R-BTA-5672958 https://reactome.org/PathwayBrowser/#/R-BTA-5672958 YWHAB dimer dissociates from KSR1:MARK3 IEA Bos taurus A0A140T894 R-BTA-5672960 https://reactome.org/PathwayBrowser/#/R-BTA-5672960 YWHAB dimer dissociates from dephosphorylated RAF IEA Bos taurus A0A140T894 R-BTA-5672961 https://reactome.org/PathwayBrowser/#/R-BTA-5672961 PP2A dephosphorylates inactive RAFs IEA Bos taurus A0A140T894 R-BTA-5672966 https://reactome.org/PathwayBrowser/#/R-BTA-5672966 RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers IEA Bos taurus A0A140T894 R-BTA-5672969 https://reactome.org/PathwayBrowser/#/R-BTA-5672969 Phosphorylation of RAF IEA Bos taurus A0A140T894 R-BTA-5672972 https://reactome.org/PathwayBrowser/#/R-BTA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Bos taurus A0A140T894 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus A0A140T894 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus A0A140T894 R-BTA-5672980 https://reactome.org/PathwayBrowser/#/R-BTA-5672980 Dissociation of RAS:RAF complex IEA Bos taurus A0A140T894 R-BTA-5675417 https://reactome.org/PathwayBrowser/#/R-BTA-5675417 PEBP1 binds activated RAF1 IEA Bos taurus A0A140T894 R-BTA-5675431 https://reactome.org/PathwayBrowser/#/R-BTA-5675431 PP2A dephosphorylates RAF1 IEA Bos taurus A0A140T894 R-BTA-5675433 https://reactome.org/PathwayBrowser/#/R-BTA-5675433 PP5 dephosphorylates RAF1 S338 IEA Bos taurus A0A140T894 R-BTA-75016 https://reactome.org/PathwayBrowser/#/R-BTA-75016 Association of p-S216-CDC25C with 14-3-3 proteins IEA Bos taurus A0A140T894 R-BTA-913993 https://reactome.org/PathwayBrowser/#/R-BTA-913993 14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 IEA Bos taurus A0A140T894 R-BTA-9610152 https://reactome.org/PathwayBrowser/#/R-BTA-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome IEA Bos taurus A0A140T894 R-BTA-9610153 https://reactome.org/PathwayBrowser/#/R-BTA-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Bos taurus A0A140T894 R-BTA-9610154 https://reactome.org/PathwayBrowser/#/R-BTA-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs IEA Bos taurus A0A140T894 R-BTA-9610156 https://reactome.org/PathwayBrowser/#/R-BTA-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Bos taurus A0A140T894 R-BTA-9610163 https://reactome.org/PathwayBrowser/#/R-BTA-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Bos taurus A0A140T894 R-BTA-9614423 https://reactome.org/PathwayBrowser/#/R-BTA-9614423 14-3-3 proteins bind AKT-phosphorylated FOXO1 IEA Bos taurus A0A140T894 R-BTA-9653108 https://reactome.org/PathwayBrowser/#/R-BTA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Bos taurus A0A140T894 R-BTA-9657599 https://reactome.org/PathwayBrowser/#/R-BTA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Bos taurus A0A140T894 R-BTA-9657603 https://reactome.org/PathwayBrowser/#/R-BTA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Bos taurus A0A140T894 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus A0A140T894 R-BTA-9657608 https://reactome.org/PathwayBrowser/#/R-BTA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Bos taurus A0A140T894 R-BTA-9658445 https://reactome.org/PathwayBrowser/#/R-BTA-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Bos taurus A0A140T896 R-BTA-200651 https://reactome.org/PathwayBrowser/#/R-BTA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Bos taurus A0A140T896 R-BTA-200735 https://reactome.org/PathwayBrowser/#/R-BTA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Bos taurus A0A140T896 R-BTA-71249 https://reactome.org/PathwayBrowser/#/R-BTA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Bos taurus A0A140T897 R-BTA-2168887 https://reactome.org/PathwayBrowser/#/R-BTA-2168887 Ferriheme is transferred from Albumin to Hemopexin IEA Bos taurus A0A140T897 R-BTA-264679 https://reactome.org/PathwayBrowser/#/R-BTA-264679 Serum albumin binds 2-lysophosphatidylcholine IEA Bos taurus A0A140T897 R-BTA-481007 https://reactome.org/PathwayBrowser/#/R-BTA-481007 Exocytosis of platelet alpha granule contents IEA Bos taurus A0A140T897 R-BTA-8952289 https://reactome.org/PathwayBrowser/#/R-BTA-8952289 FAM20C phosphorylates FAM20C substrates IEA Bos taurus A0A140T897 R-BTA-9661419 https://reactome.org/PathwayBrowser/#/R-BTA-9661419 ALB binds extracellular heme IEA Bos taurus A0A140T897 R-BTA-9661425 https://reactome.org/PathwayBrowser/#/R-BTA-9661425 BIL:ALB dissociates IEA Bos taurus A0A140T897 R-BTA-9661432 https://reactome.org/PathwayBrowser/#/R-BTA-9661432 BIL binds ALB IEA Bos taurus A0A140T897 R-BTA-9709883 https://reactome.org/PathwayBrowser/#/R-BTA-9709883 BIL:ALB scavenges O2.- IEA Bos taurus A0A140T897 R-BTA-9733545 https://reactome.org/PathwayBrowser/#/R-BTA-9733545 Bile salts and acids bind ALB IEA Bos taurus A0A140T897 R-BTA-9733960 https://reactome.org/PathwayBrowser/#/R-BTA-9733960 Bile salts and acids dissociate from ALB IEA Bos taurus A0A140T897 R-BTA-9749590 https://reactome.org/PathwayBrowser/#/R-BTA-9749590 ASA- acetylates ALB IEA Bos taurus A0A140T897 R-BTA-9750666 https://reactome.org/PathwayBrowser/#/R-BTA-9750666 ALB binds ST IEA Bos taurus A0A140T897 R-BTA-9757574 https://reactome.org/PathwayBrowser/#/R-BTA-9757574 ALB binds PREDL IEA Bos taurus A0A140T897 R-BTA-9757578 https://reactome.org/PathwayBrowser/#/R-BTA-9757578 ALB binds PREDN IEA Bos taurus A0A140T897 R-BTA-9762343 https://reactome.org/PathwayBrowser/#/R-BTA-9762343 PREDL:ALB dissociates IEA Bos taurus A0A140T897 R-BTA-9762345 https://reactome.org/PathwayBrowser/#/R-BTA-9762345 PREDN:ALB dissociates IEA Bos taurus A0A140T897 R-BTA-9794444 https://reactome.org/PathwayBrowser/#/R-BTA-9794444 ALB binds Cipro IEA Bos taurus A0A140T897 R-BTA-9794475 https://reactome.org/PathwayBrowser/#/R-BTA-9794475 Cipro:ALB dissociates IEA Bos taurus A0A140T898 R-BTA-8870466 https://reactome.org/PathwayBrowser/#/R-BTA-8870466 RGGT:CHM binds RABs IEA Bos taurus A0A140T898 R-BTA-8870469 https://reactome.org/PathwayBrowser/#/R-BTA-8870469 RGGT geranylgeranylates RAB proteins IEA Bos taurus A0A140T898 R-BTA-8876615 https://reactome.org/PathwayBrowser/#/R-BTA-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Bos taurus A0A140T8A2 R-BTA-5358494 https://reactome.org/PathwayBrowser/#/R-BTA-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Bos taurus A0A140T8A5 R-BTA-389540 https://reactome.org/PathwayBrowser/#/R-BTA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Bos taurus A0A140T8A5 R-BTA-389550 https://reactome.org/PathwayBrowser/#/R-BTA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Bos taurus A0A140T8A5 R-BTA-6798745 https://reactome.org/PathwayBrowser/#/R-BTA-6798745 Exocytosis of tertiary granule lumen proteins IEA Bos taurus A0A140T8A5 R-BTA-6798748 https://reactome.org/PathwayBrowser/#/R-BTA-6798748 Exocytosis of secretory granule lumen proteins IEA Bos taurus A0A140T8A5 R-BTA-6800434 https://reactome.org/PathwayBrowser/#/R-BTA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Bos taurus A0A140T8A5 R-BTA-9033235 https://reactome.org/PathwayBrowser/#/R-BTA-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Bos taurus A0A140T8A5 R-BTA-9033236 https://reactome.org/PathwayBrowser/#/R-BTA-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Bos taurus A0A140T8A9 R-BTA-5340124 https://reactome.org/PathwayBrowser/#/R-BTA-5340124 CSN polymer binds CaPO4 IEA Bos taurus A0A140T8B2 R-BTA-159101 https://reactome.org/PathwayBrowser/#/R-BTA-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Bos taurus A0A140T8B2 R-BTA-72180 https://reactome.org/PathwayBrowser/#/R-BTA-72180 Cleavage of mRNA at the 3'-end IEA Bos taurus A0A140T8B2 R-BTA-72185 https://reactome.org/PathwayBrowser/#/R-BTA-72185 mRNA polyadenylation IEA Bos taurus A0A140T8B5 R-BTA-2424480 https://reactome.org/PathwayBrowser/#/R-BTA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Bos taurus A0A140T8B8 R-BTA-2453833 https://reactome.org/PathwayBrowser/#/R-BTA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Bos taurus A0A140T8B9 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus A0A140T8B9 R-BTA-416929 https://reactome.org/PathwayBrowser/#/R-BTA-416929 PTGFR binds PGF2a IEA Bos taurus A0A140T8B9 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus A0A140T8B9 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus A0A140T8B9 R-BTA-9718020 https://reactome.org/PathwayBrowser/#/R-BTA-9718020 PTGFR binds PTGFR agonists IEA Bos taurus A0A140T8C6 R-BTA-1605591 https://reactome.org/PathwayBrowser/#/R-BTA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Bos taurus A0A140T8C6 R-BTA-1605624 https://reactome.org/PathwayBrowser/#/R-BTA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Bos taurus A0A140T8C6 R-BTA-1605632 https://reactome.org/PathwayBrowser/#/R-BTA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Bos taurus A0A140T8C6 R-BTA-1605724 https://reactome.org/PathwayBrowser/#/R-BTA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Bos taurus A0A140T8C6 R-BTA-1605736 https://reactome.org/PathwayBrowser/#/R-BTA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Bos taurus A0A140T8C6 R-BTA-1606312 https://reactome.org/PathwayBrowser/#/R-BTA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Bos taurus A0A140T8C6 R-BTA-1606564 https://reactome.org/PathwayBrowser/#/R-BTA-1606564 GALC hydrolyzes GalCer IEA Bos taurus A0A140T8C6 R-BTA-1606602 https://reactome.org/PathwayBrowser/#/R-BTA-1606602 ASAH1 hydrolyzes ceramide IEA Bos taurus A0A140T8C6 R-BTA-1606807 https://reactome.org/PathwayBrowser/#/R-BTA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Bos taurus A0A140T8C6 R-BTA-351341 https://reactome.org/PathwayBrowser/#/R-BTA-351341 Exocytosis of Proactivator polypeptide IEA Bos taurus A0A140T8C6 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus A0A140T8C6 R-BTA-5336182 https://reactome.org/PathwayBrowser/#/R-BTA-5336182 GPR37 binds prosaptide IEA Bos taurus A0A140T8C6 R-BTA-5336184 https://reactome.org/PathwayBrowser/#/R-BTA-5336184 GPR37L binds prosaposin IEA Bos taurus A0A140T8C6 R-BTA-6798739 https://reactome.org/PathwayBrowser/#/R-BTA-6798739 Exocytosis of azurophil granule membrane proteins IEA Bos taurus A0A140T8C6 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus A0A140T8C6 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus A0A140T8C6 R-BTA-9840334 https://reactome.org/PathwayBrowser/#/R-BTA-9840334 PSAP gets cleaved IEA Bos taurus A0A140T8C6 R-BTA-9840470 https://reactome.org/PathwayBrowser/#/R-BTA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Bos taurus A0A140T8C6 R-BTA-9840488 https://reactome.org/PathwayBrowser/#/R-BTA-9840488 PSAP(195-273) forms a dimer IEA Bos taurus A0A140T8C6 R-BTA-9841189 https://reactome.org/PathwayBrowser/#/R-BTA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Bos taurus A0A140T8C6 R-BTA-9842115 https://reactome.org/PathwayBrowser/#/R-BTA-9842115 PSAP(195-273) dimer binds PE IEA Bos taurus A0A140T8C7 R-BTA-176298 https://reactome.org/PathwayBrowser/#/R-BTA-176298 Activation of claspin IEA Bos taurus A0A140T8C7 R-BTA-176318 https://reactome.org/PathwayBrowser/#/R-BTA-176318 Loading of claspin onto DNA during replication origin firing IEA Bos taurus A0A140T8C7 R-BTA-68611 https://reactome.org/PathwayBrowser/#/R-BTA-68611 Formation of ORC(1-5) complex IEA Bos taurus A0A140T8C7 R-BTA-68615 https://reactome.org/PathwayBrowser/#/R-BTA-68615 Formation of ORC(1-6) complex IEA Bos taurus A0A140T8C7 R-BTA-68688 https://reactome.org/PathwayBrowser/#/R-BTA-68688 CDC6 association with ORC(1-6) at replication origins IEA Bos taurus A0A140T8C7 R-BTA-68914 https://reactome.org/PathwayBrowser/#/R-BTA-68914 DNA polymerase alpha:primase binds at the origin IEA Bos taurus A0A140T8C7 R-BTA-68916 https://reactome.org/PathwayBrowser/#/R-BTA-68916 DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin IEA Bos taurus A0A140T8C7 R-BTA-68917 https://reactome.org/PathwayBrowser/#/R-BTA-68917 Cdc45 associates with the pre-replicative complex at the origin IEA Bos taurus A0A140T8C7 R-BTA-68918 https://reactome.org/PathwayBrowser/#/R-BTA-68918 CDK and DDK associate with the Mcm10:pre-replicative complex IEA Bos taurus A0A140T8C7 R-BTA-68919 https://reactome.org/PathwayBrowser/#/R-BTA-68919 Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 IEA Bos taurus A0A140T8C7 R-BTA-68940 https://reactome.org/PathwayBrowser/#/R-BTA-68940 Cdt1 is displaced from the pre-replicative complex IEA Bos taurus A0A140T8C7 R-BTA-68944 https://reactome.org/PathwayBrowser/#/R-BTA-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Bos taurus A0A140T8C7 R-BTA-68946 https://reactome.org/PathwayBrowser/#/R-BTA-68946 Phosphorylated Orc1 is ubiquitinated while still associated with chromatin IEA Bos taurus A0A140T8C7 R-BTA-68947 https://reactome.org/PathwayBrowser/#/R-BTA-68947 Ubiquitinated Orc1 enters the cytosol IEA Bos taurus A0A140T8C7 R-BTA-68948 https://reactome.org/PathwayBrowser/#/R-BTA-68948 Ubiquitinated Orc1 is degraded by the proteasome IEA Bos taurus A0A140T8C7 R-BTA-68960 https://reactome.org/PathwayBrowser/#/R-BTA-68960 DNA polymerase epsilon binds at the origin IEA Bos taurus A0A140T8C7 R-BTA-9734730 https://reactome.org/PathwayBrowser/#/R-BTA-9734730 ORC1 translocates to the nucleus IEA Bos taurus A0A140T8C7 R-BTA-9749197 https://reactome.org/PathwayBrowser/#/R-BTA-9749197 ORC1 binds to H4K20me2 IEA Bos taurus A0A140T8C8 R-BTA-158218 https://reactome.org/PathwayBrowser/#/R-BTA-158218 prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer IEA Bos taurus A0A140T8C8 R-BTA-158251 https://reactome.org/PathwayBrowser/#/R-BTA-158251 prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer IEA Bos taurus A0A140T8C8 R-BTA-158311 https://reactome.org/PathwayBrowser/#/R-BTA-158311 kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin IEA Bos taurus A0A140T8C8 R-BTA-158313 https://reactome.org/PathwayBrowser/#/R-BTA-158313 factor XII -> factor XIIa IEA Bos taurus A0A140T8C8 R-BTA-158354 https://reactome.org/PathwayBrowser/#/R-BTA-158354 kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer IEA Bos taurus A0A140T8C8 R-BTA-374331 https://reactome.org/PathwayBrowser/#/R-BTA-374331 Bradykinin receptors B1 and B2 bind to bradykinin IEA Bos taurus A0A140T8C8 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus A0A140T8C8 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus A0A140T8C8 R-BTA-481007 https://reactome.org/PathwayBrowser/#/R-BTA-481007 Exocytosis of platelet alpha granule contents IEA Bos taurus A0A140T8C8 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus A0A140T8C8 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus A0A140T8C8 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus A0A140T8C8 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus A0A140T8C8 R-BTA-8952289 https://reactome.org/PathwayBrowser/#/R-BTA-8952289 FAM20C phosphorylates FAM20C substrates IEA Bos taurus A0A140T8D2 R-BTA-198941 https://reactome.org/PathwayBrowser/#/R-BTA-198941 VCAM1 binds Integrin alpha4beta1 IEA Bos taurus A0A140T8D2 R-BTA-202706 https://reactome.org/PathwayBrowser/#/R-BTA-202706 Integrin alpha4beta1 binds JAM2:JAM3 IEA Bos taurus A0A140T8D2 R-BTA-202723 https://reactome.org/PathwayBrowser/#/R-BTA-202723 Integrin alpha5beta1 binds FN1 dimer IEA Bos taurus A0A140T8D2 R-BTA-204434 https://reactome.org/PathwayBrowser/#/R-BTA-204434 BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 IEA Bos taurus A0A140T8D2 R-BTA-216043 https://reactome.org/PathwayBrowser/#/R-BTA-216043 Collagen type II binds integrin alpha10beta1 IEA Bos taurus A0A140T8D2 R-BTA-216045 https://reactome.org/PathwayBrowser/#/R-BTA-216045 Collagen type I binds integrin alpha11beta1 IEA Bos taurus A0A140T8D2 R-BTA-216048 https://reactome.org/PathwayBrowser/#/R-BTA-216048 Integrins alpha3beta1, alpha6beta4 bind laminin-332, 511, 521, (211, 221) IEA Bos taurus A0A140T8D2 R-BTA-216050 https://reactome.org/PathwayBrowser/#/R-BTA-216050 Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix IEA Bos taurus A0A140T8D2 R-BTA-216058 https://reactome.org/PathwayBrowser/#/R-BTA-216058 Integrin alpha7beta1 binds Laminin-211, 221, 411, 512, 521 IEA Bos taurus A0A140T8D2 R-BTA-216064 https://reactome.org/PathwayBrowser/#/R-BTA-216064 Interaction of integrin alpha8beta1 with Tenascin-C IEA Bos taurus A0A140T8D2 R-BTA-216068 https://reactome.org/PathwayBrowser/#/R-BTA-216068 Interaction of integrin alpha9beta1 with Tenascin-C IEA Bos taurus A0A140T8D2 R-BTA-2327695 https://reactome.org/PathwayBrowser/#/R-BTA-2327695 Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 IEA Bos taurus A0A140T8D2 R-BTA-2327746 https://reactome.org/PathwayBrowser/#/R-BTA-2327746 FN1 aggregation IEA Bos taurus A0A140T8D2 R-BTA-2328037 https://reactome.org/PathwayBrowser/#/R-BTA-2328037 Fibrillin-1 binds integrins IEA Bos taurus A0A140T8D2 R-BTA-2395320 https://reactome.org/PathwayBrowser/#/R-BTA-2395320 Latent TGF-beta-1 binds integrins IEA Bos taurus A0A140T8D2 R-BTA-2396029 https://reactome.org/PathwayBrowser/#/R-BTA-2396029 Latent TGF-beta-3 binds integrins IEA Bos taurus A0A140T8D2 R-BTA-2426259 https://reactome.org/PathwayBrowser/#/R-BTA-2426259 COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 IEA Bos taurus A0A140T8D2 R-BTA-2426471 https://reactome.org/PathwayBrowser/#/R-BTA-2426471 VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 IEA Bos taurus A0A140T8D2 R-BTA-2484965 https://reactome.org/PathwayBrowser/#/R-BTA-2484965 Collagen type XIII binds Integrin alpha1beta1 IEA Bos taurus A0A140T8D2 R-BTA-265424 https://reactome.org/PathwayBrowser/#/R-BTA-265424 SPP1 (osteopontin) binds integrin alpha5beta1, alpha9beta1 IEA Bos taurus A0A140T8D2 R-BTA-265428 https://reactome.org/PathwayBrowser/#/R-BTA-265428 Interaction of integrin alpha9beta1 with VCAM1 IEA Bos taurus A0A140T8D2 R-BTA-265429 https://reactome.org/PathwayBrowser/#/R-BTA-265429 THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1 IEA Bos taurus A0A140T8D2 R-BTA-2681667 https://reactome.org/PathwayBrowser/#/R-BTA-2681667 TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 IEA Bos taurus A0A140T8D2 R-BTA-2731074 https://reactome.org/PathwayBrowser/#/R-BTA-2731074 Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) IEA Bos taurus A0A140T8D2 R-BTA-3907292 https://reactome.org/PathwayBrowser/#/R-BTA-3907292 Integrin alpha6beta1 binds laminin-322, 512, 521, 211, 221, 411 IEA Bos taurus A0A140T8D2 R-BTA-4084903 https://reactome.org/PathwayBrowser/#/R-BTA-4084903 Collagen types VI, IX bind integrin alpha10beta1 IEA Bos taurus A0A140T8D2 R-BTA-4084912 https://reactome.org/PathwayBrowser/#/R-BTA-4084912 Arresten binds integrin alpha1beta1 IEA Bos taurus A0A140T8D2 R-BTA-4085083 https://reactome.org/PathwayBrowser/#/R-BTA-4085083 Tumstatin binds integrin alphaVbeta 3, alpha3beta1 IEA Bos taurus A0A140T8D2 R-BTA-4085133 https://reactome.org/PathwayBrowser/#/R-BTA-4085133 LUM (lumican) binds integrin alpha2beta1 IEA Bos taurus A0A140T8D2 R-BTA-4086132 https://reactome.org/PathwayBrowser/#/R-BTA-4086132 Dentin phosphoprotein binds integrin alphaVbeta1 IEA Bos taurus A0A140T8D2 R-BTA-4088264 https://reactome.org/PathwayBrowser/#/R-BTA-4088264 Endostatin binds integrin alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 IEA Bos taurus A0A140T8D2 R-BTA-432897 https://reactome.org/PathwayBrowser/#/R-BTA-432897 ILK interacts with beta-1 integrin IEA Bos taurus A0A140T8D2 R-BTA-8874079 https://reactome.org/PathwayBrowser/#/R-BTA-8874079 PTK2 binds activated MET IEA Bos taurus A0A140T8D2 R-BTA-8875531 https://reactome.org/PathwayBrowser/#/R-BTA-8875531 MET binds TNS4 IEA Bos taurus A0A140T8D2 R-BTA-9013145 https://reactome.org/PathwayBrowser/#/R-BTA-9013145 RAC1 binds effectors at the plasma membrane IEA Bos taurus A0A140T8D2 R-BTA-9014294 https://reactome.org/PathwayBrowser/#/R-BTA-9014294 RAC2 binds effectors at the plasma membrane IEA Bos taurus A0A140T8D2 R-BTA-9014449 https://reactome.org/PathwayBrowser/#/R-BTA-9014449 RHOG binds effectors at the plasma membrane IEA Bos taurus A0A140T8D2 R-BTA-9018808 https://reactome.org/PathwayBrowser/#/R-BTA-9018808 RAC3 binds effectors at the plasma membrane IEA Bos taurus A0A140T8D2 R-BTA-9624017 https://reactome.org/PathwayBrowser/#/R-BTA-9624017 p-SHC1 binds integrin alpha5beta1:fibronectin IEA Bos taurus A0A140T8D2 R-BTA-9679740 https://reactome.org/PathwayBrowser/#/R-BTA-9679740 ITGA4:ITGB1 binds natalizumab IEA Bos taurus A0A140T8D2 R-BTA-9861484 https://reactome.org/PathwayBrowser/#/R-BTA-9861484 Phosphorylation of PTK2 (FAK) on tyrosine-397 in response to turbulent blood flow IEA Bos taurus A0A140T8D2 R-BTA-9865184 https://reactome.org/PathwayBrowser/#/R-BTA-9865184 Phosphorylation of ABL1 on tyrosine-393 in response to oscillatory shear stress IEA Bos taurus A0A140T8D2 R-BTA-9865215 https://reactome.org/PathwayBrowser/#/R-BTA-9865215 p-S26-ANXA2 binds integrin alpha5:beta1 at the plasma membrane IEA Bos taurus A0A140T8D2 R-BTA-9865226 https://reactome.org/PathwayBrowser/#/R-BTA-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Bos taurus A0A140T8D3 R-BTA-8952289 https://reactome.org/PathwayBrowser/#/R-BTA-8952289 FAM20C phosphorylates FAM20C substrates IEA Bos taurus A0A140T8D4 R-BTA-1678920 https://reactome.org/PathwayBrowser/#/R-BTA-1678920 TLR processing at low pH IEA Bos taurus A0A140T8D4 R-BTA-2130336 https://reactome.org/PathwayBrowser/#/R-BTA-2130336 Initial proteolyis of Ii by aspartic proteases to lip22 IEA Bos taurus A0A140T8D4 R-BTA-350158 https://reactome.org/PathwayBrowser/#/R-BTA-350158 LGMN degrades GC IEA Bos taurus A0A140T8F4 R-GGA-163090 https://reactome.org/PathwayBrowser/#/R-GGA-163090 Elongation Of The Telomeric Chromosome End IEA Gallus gallus A0A140T8F4 R-GGA-163099 https://reactome.org/PathwayBrowser/#/R-GGA-163099 Alignment Of The RNA Template On The Telomeric Chromosome End IEA Gallus gallus A0A140T8F4 R-GGA-164617 https://reactome.org/PathwayBrowser/#/R-GGA-164617 Elongation of Extended Telomeric Chromosome End IEA Gallus gallus A0A140T8F4 R-GGA-164620 https://reactome.org/PathwayBrowser/#/R-GGA-164620 Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End IEA Gallus gallus A0A140T8F4 R-GGA-174425 https://reactome.org/PathwayBrowser/#/R-GGA-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Gallus gallus A0A140T8F4 R-GGA-174427 https://reactome.org/PathwayBrowser/#/R-GGA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Gallus gallus A0A140T8F4 R-GGA-174439 https://reactome.org/PathwayBrowser/#/R-GGA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Gallus gallus A0A140T8F4 R-GGA-174452 https://reactome.org/PathwayBrowser/#/R-GGA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Gallus gallus A0A140T8F5 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A140T8G5 R-GGA-191983 https://reactome.org/PathwayBrowser/#/R-GGA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Gallus gallus A0A140T8H2 R-GGA-1462023 https://reactome.org/PathwayBrowser/#/R-GGA-1462023 Pre-pro-defensins are cleaved to remove the signal peptide IEA Gallus gallus A0A140T8H2 R-GGA-1467269 https://reactome.org/PathwayBrowser/#/R-GGA-1467269 Beta-defensins bind microbial membranes causing disruption IEA Gallus gallus A0A140T8H2 R-GGA-1471322 https://reactome.org/PathwayBrowser/#/R-GGA-1471322 Beta-defensins are secreted IEA Gallus gallus A0A140T8H2 R-GGA-1471338 https://reactome.org/PathwayBrowser/#/R-GGA-1471338 Beta-defensins 1, 4A and 103 bind CCR6 IEA Gallus gallus A0A140T8H2 R-GGA-1973968 https://reactome.org/PathwayBrowser/#/R-GGA-1973968 Beta-defensins 4A and 103 bind CCR2 IEA Gallus gallus A0A140T8H4 R-GGA-1462023 https://reactome.org/PathwayBrowser/#/R-GGA-1462023 Pre-pro-defensins are cleaved to remove the signal peptide IEA Gallus gallus A0A140T8H4 R-GGA-1467269 https://reactome.org/PathwayBrowser/#/R-GGA-1467269 Beta-defensins bind microbial membranes causing disruption IEA Gallus gallus A0A140T8H4 R-GGA-1471322 https://reactome.org/PathwayBrowser/#/R-GGA-1471322 Beta-defensins are secreted IEA Gallus gallus A0A140T8H4 R-GGA-1471338 https://reactome.org/PathwayBrowser/#/R-GGA-1471338 Beta-defensins 1, 4A and 103 bind CCR6 IEA Gallus gallus A0A140T8H4 R-GGA-1973968 https://reactome.org/PathwayBrowser/#/R-GGA-1973968 Beta-defensins 4A and 103 bind CCR2 IEA Gallus gallus A0A140T8H4 R-GGA-1974676 https://reactome.org/PathwayBrowser/#/R-GGA-1974676 Beta defensin 103 activates TLR1:TLR2 IEA Gallus gallus A0A140T8H6 R-GGA-168915 https://reactome.org/PathwayBrowser/#/R-GGA-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex IEA Gallus gallus A0A140T8H6 R-GGA-202960 https://reactome.org/PathwayBrowser/#/R-GGA-202960 Caspase mediated cleavage of C-IAP1 IEA Gallus gallus A0A140T8H6 R-GGA-5357757 https://reactome.org/PathwayBrowser/#/R-GGA-5357757 BIRC(cIAP1/2) ubiquitinates RIPK1 IEA Gallus gallus A0A140T8H6 R-GGA-5357780 https://reactome.org/PathwayBrowser/#/R-GGA-5357780 TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) IEA Gallus gallus A0A140T8H6 R-GGA-5357845 https://reactome.org/PathwayBrowser/#/R-GGA-5357845 K63polyUb-RIPK1 is deubiquitinated IEA Gallus gallus A0A140T8H6 R-GGA-5668414 https://reactome.org/PathwayBrowser/#/R-GGA-5668414 TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK IEA Gallus gallus A0A140T8H6 R-GGA-5668454 https://reactome.org/PathwayBrowser/#/R-GGA-5668454 K63polyUb-cIAP1,2 ubiquitinates TRAF3 IEA Gallus gallus A0A140T8H6 R-GGA-5668481 https://reactome.org/PathwayBrowser/#/R-GGA-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Gallus gallus A0A140T8H6 R-GGA-5668534 https://reactome.org/PathwayBrowser/#/R-GGA-5668534 cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK IEA Gallus gallus A0A140T8H6 R-GGA-5668543 https://reactome.org/PathwayBrowser/#/R-GGA-5668543 TRAF3:NIK binds TRAF2:cIAP1/2 IEA Gallus gallus A0A140T8H6 R-GGA-5675470 https://reactome.org/PathwayBrowser/#/R-GGA-5675470 BIRC2/3 (cIAP1/2) is autoubiquitinated IEA Gallus gallus A0A140T8H6 R-GGA-5676595 https://reactome.org/PathwayBrowser/#/R-GGA-5676595 TRAFs bind RANK:RANKL IEA Gallus gallus A0A140T8H6 R-GGA-5676596 https://reactome.org/PathwayBrowser/#/R-GGA-5676596 TRAF3 binds BAFFR:BAFF IEA Gallus gallus A0A140T8H6 R-GGA-5676597 https://reactome.org/PathwayBrowser/#/R-GGA-5676597 TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 IEA Gallus gallus A0A140T8H6 R-GGA-5693055 https://reactome.org/PathwayBrowser/#/R-GGA-5693055 TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes IEA Gallus gallus A0A140T8H6 R-GGA-5693108 https://reactome.org/PathwayBrowser/#/R-GGA-5693108 TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains IEA Gallus gallus A0A140T8H6 R-GGA-6781797 https://reactome.org/PathwayBrowser/#/R-GGA-6781797 USP19 binds HIF1A,BIRC2,BIRC3 IEA Gallus gallus A0A140T8H6 R-GGA-9817397 https://reactome.org/PathwayBrowser/#/R-GGA-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Gallus gallus A0A140T8H7 R-GGA-1462023 https://reactome.org/PathwayBrowser/#/R-GGA-1462023 Pre-pro-defensins are cleaved to remove the signal peptide IEA Gallus gallus A0A140T8H7 R-GGA-1467269 https://reactome.org/PathwayBrowser/#/R-GGA-1467269 Beta-defensins bind microbial membranes causing disruption IEA Gallus gallus A0A140T8H7 R-GGA-1471322 https://reactome.org/PathwayBrowser/#/R-GGA-1471322 Beta-defensins are secreted IEA Gallus gallus A0A140T8H7 R-GGA-1471338 https://reactome.org/PathwayBrowser/#/R-GGA-1471338 Beta-defensins 1, 4A and 103 bind CCR6 IEA Gallus gallus A0A140T8H7 R-GGA-1973968 https://reactome.org/PathwayBrowser/#/R-GGA-1973968 Beta-defensins 4A and 103 bind CCR2 IEA Gallus gallus A0A140T8H9 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A140T8H9 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A140T8H9 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A140T8H9 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A140T8H9 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A140T8H9 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A140T8H9 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A140T8H9 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A140T8H9 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A140T8H9 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A140T8H9 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A140T8M0 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A140T8M0 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A140T8M0 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A140T8M0 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A140T8M0 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A140T8M0 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A140T8M0 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A140T8M0 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A140T8M0 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A140T8M0 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A140T8M0 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A140T8M0 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A140T8M0 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A140T8M0 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A140T8M0 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A140T8M0 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A140T8M0 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A140T8M0 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A140T8M0 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A140T8M0 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A140T8M0 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A140T8M0 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A140T8M0 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A140T8M0 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A140T8M0 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A140T8M0 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A140T8M0 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A140T8M0 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A140T8M0 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A140T8M0 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A140T8M0 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A140T8M0 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A140T8M0 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A140T8M0 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A140T8M0 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A140T8M0 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A140T8M0 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A140T8M0 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A140T8M0 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A140T8M0 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A140T8M0 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A140T8M0 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A140T8M0 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A140T8M0 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A140T8M0 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A140T8M0 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A140T8M0 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A140T8M8 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A140T8M8 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A140T8M8 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A140T8M8 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A140T8M8 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A140T8M8 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A140T8M8 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A140T8M8 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A140T8M8 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A140T8M8 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A140T8M8 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A140T8M8 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A140T8M8 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A140T8M8 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A140T8M8 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A140T8M8 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A140T8M8 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A140T8M8 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A140T8M8 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A140T8M8 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A140T8M8 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A140T8M8 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A140T8M8 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A140T8M8 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A140T8M8 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A140T8M8 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A140T8M8 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A140T8M8 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A140T8M8 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A140T8M8 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A140T8M8 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A140T8M8 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A140T8M8 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A140T8M8 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A140T8M8 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A140T8M8 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A140T8M8 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A140T8M8 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A140T8M8 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A140T8M8 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A140T8M8 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A140T8M8 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A140T8M8 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A140T8M8 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A140T8M8 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A140T8M8 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A140T8M8 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A140T8M9 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A140T8M9 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A140T8M9 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A140T8M9 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A140T8M9 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A140T8M9 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A140T8M9 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A140T8M9 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A140T8M9 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A140T8M9 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A140T8M9 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A140T8M9 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A140T8M9 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A140T8M9 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A140T8M9 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A140T8M9 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A140T8M9 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A140T8M9 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A140T8M9 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A140T8M9 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A140T8M9 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A140T8M9 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A140T8M9 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A140T8M9 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A140T8M9 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A140T8M9 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A140T8M9 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A140T8M9 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A140T8M9 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A140T8M9 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A140T8M9 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A140T8M9 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A140T8M9 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A140T8M9 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A140T8M9 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A140T8M9 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A140T8M9 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A140T8M9 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A140T8M9 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A140T8M9 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A140T8M9 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A140T8M9 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A140T8M9 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A140T8M9 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A140T8M9 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A140T8M9 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A140T8M9 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A140T8N1 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A140T8N1 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A140T8N1 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A140T8N1 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A140T8N1 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A140T8N1 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A140T8N1 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A140T8N1 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A140T8N1 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A140T8N1 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A140T8N1 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A140T8N1 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A140T8N1 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A140T8N1 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A140T8N1 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A140T8N1 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A140T8N1 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A140T8N1 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A140T8N1 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A140T8N1 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A140T8N1 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A140T8N1 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A140T8N1 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A140T8N1 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A140T8N1 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A140T8N1 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A140T8N1 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A140T8N1 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A140T8N1 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A140T8N1 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A140T8N1 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A140T8N1 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A140T8N1 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A140T8N1 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A140T8N1 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A140T8N1 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A140T8N1 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A140T8N1 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A140T8N1 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A140T8N1 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A140T8N1 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A140T8N1 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A140T8N1 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A140T8N1 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A140T8N1 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A140T8N1 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A140T8N1 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A140T8P3 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A140T8P3 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A140T8P3 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A140T8P3 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A140T8P3 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A140T8P3 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A140T8P3 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A140T8P3 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A140T8P3 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A140T8P3 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A140T8P3 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A140T8P3 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A140T8P3 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A140T8P3 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A140T8P3 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A140T8P3 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A140T8P3 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A140T8P3 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A140T8P3 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A140T8P3 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A140T8P3 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A140T8P3 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A140T8P3 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A140T8P3 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A140T8P3 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A140T8P3 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A140T8P3 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A140T8P3 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A140T8P3 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A140T8P3 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A140T8P3 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A140T8P3 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A140T8P3 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A140T8P3 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A140T8P3 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A140T8P3 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A140T8P3 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A140T8P3 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A140T8P3 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A140T8P3 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A140T8P3 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A140T8P3 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A140T8P3 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A140T8P3 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A140T8P3 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A140T8P3 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A140T8P3 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A140T8P7 R-MMU-1112666 https://reactome.org/PathwayBrowser/#/R-MMU-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Mus musculus A0A140T8P7 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A140T8P7 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A140T8P7 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A140T8P7 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A140T8P7 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A140T8P7 R-MMU-199161 https://reactome.org/PathwayBrowser/#/R-MMU-199161 Fc gamma receptors interact with antigen-bound IgG IEA Mus musculus A0A140T8P7 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A140T8P7 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A140T8P7 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A140T8P7 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A140T8P7 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A140T8P7 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A140T8P7 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A140T8P7 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A140T8P7 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A140T8P7 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A140T8P7 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A140T8P7 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A140T8P7 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A140T8P7 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A140T8P7 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A140T8P7 R-MMU-2203516 https://reactome.org/PathwayBrowser/#/R-MMU-2203516 Alpha-1-Microglobulin is cleaved IEA Mus musculus A0A140T8P7 R-MMU-2454192 https://reactome.org/PathwayBrowser/#/R-MMU-2454192 Allergen dependent IgE bound FCERI aggregation IEA Mus musculus A0A140T8P7 R-MMU-2454208 https://reactome.org/PathwayBrowser/#/R-MMU-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Mus musculus A0A140T8P7 R-MMU-2454240 https://reactome.org/PathwayBrowser/#/R-MMU-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Mus musculus A0A140T8P7 R-MMU-2730833 https://reactome.org/PathwayBrowser/#/R-MMU-2730833 Phosphorylation of TEC kinases by p-SYK IEA Mus musculus A0A140T8P7 R-MMU-2730843 https://reactome.org/PathwayBrowser/#/R-MMU-2730843 Phosphorylation of LAT by p-SYK IEA Mus musculus A0A140T8P7 R-MMU-2730851 https://reactome.org/PathwayBrowser/#/R-MMU-2730851 Phosphorylation of SLP-76 by p-SYK IEA Mus musculus A0A140T8P7 R-MMU-2730882 https://reactome.org/PathwayBrowser/#/R-MMU-2730882 Phosphorylation of PKC-theta IEA Mus musculus A0A140T8P7 R-MMU-2730884 https://reactome.org/PathwayBrowser/#/R-MMU-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Mus musculus A0A140T8P7 R-MMU-2730886 https://reactome.org/PathwayBrowser/#/R-MMU-2730886 Phosphorylation of SHC by SYK kinase IEA Mus musculus A0A140T8P7 R-MMU-5690701 https://reactome.org/PathwayBrowser/#/R-MMU-5690701 SHP1 binds p-CD22 IEA Mus musculus A0A140T8P7 R-MMU-5690702 https://reactome.org/PathwayBrowser/#/R-MMU-5690702 LYN phosphorylates CD22 IEA Mus musculus A0A140T8P7 R-MMU-5690740 https://reactome.org/PathwayBrowser/#/R-MMU-5690740 CD22 binds B-cell receptor IEA Mus musculus A0A140T8P7 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A140T8P7 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A140T8P7 R-MMU-8858428 https://reactome.org/PathwayBrowser/#/R-MMU-8858428 FCAMR binds IgA IEA Mus musculus A0A140T8P7 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A140T8P7 R-MMU-9606151 https://reactome.org/PathwayBrowser/#/R-MMU-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Mus musculus A0A140T8P7 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus A0A140T8P7 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus A0A140T8P7 R-MMU-9725206 https://reactome.org/PathwayBrowser/#/R-MMU-9725206 IgE binds FCERI IEA Mus musculus A0A140T8P7 R-MMU-983696 https://reactome.org/PathwayBrowser/#/R-MMU-983696 The Immunoglobulin of the BCR binds antigen IEA Mus musculus A0A140T8P7 R-MMU-983700 https://reactome.org/PathwayBrowser/#/R-MMU-983700 SYK binds the activated BCR IEA Mus musculus A0A140T8P7 R-MMU-983703 https://reactome.org/PathwayBrowser/#/R-MMU-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Mus musculus A0A140T8P7 R-MMU-983707 https://reactome.org/PathwayBrowser/#/R-MMU-983707 SYK autophosphorylates at the activated BCR IEA Mus musculus A0A140TAJ4 R-RNO-193052 https://reactome.org/PathwayBrowser/#/R-RNO-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Rattus norvegicus A0A140TAJ4 R-RNO-193073 https://reactome.org/PathwayBrowser/#/R-RNO-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Rattus norvegicus A0A140TAJ4 R-RNO-193961 https://reactome.org/PathwayBrowser/#/R-RNO-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Rattus norvegicus A0A140TAJ4 R-RNO-196350 https://reactome.org/PathwayBrowser/#/R-RNO-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Rattus norvegicus A0A140TAJ4 R-RNO-196372 https://reactome.org/PathwayBrowser/#/R-RNO-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Rattus norvegicus A0A140TAJ7 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A140TAJ7 R-SSC-444208 https://reactome.org/PathwayBrowser/#/R-SSC-444208 MLNR (GPR38) is a receptor for motilin IEA Sus scrofa A0A140TAJ7 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A140TAJ7 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A140TAK4 R-SSC-193665 https://reactome.org/PathwayBrowser/#/R-SSC-193665 MYD88 dissociates IEA Sus scrofa A0A140TAK4 R-SSC-193695 https://reactome.org/PathwayBrowser/#/R-SSC-193695 IRAK interacts with TRAF6 IEA Sus scrofa A0A140TAK4 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A140TAK4 R-SSC-3134953 https://reactome.org/PathwayBrowser/#/R-SSC-3134953 DHX36 or DHX9 binds MyD88 IEA Sus scrofa A0A140TAK4 R-SSC-446634 https://reactome.org/PathwayBrowser/#/R-SSC-446634 IRAK4 is activated by autophosphorylation IEA Sus scrofa A0A140TAK4 R-SSC-446648 https://reactome.org/PathwayBrowser/#/R-SSC-446648 IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 IEA Sus scrofa A0A140TAK4 R-SSC-446684 https://reactome.org/PathwayBrowser/#/R-SSC-446684 IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation IEA Sus scrofa A0A140TAK4 R-SSC-446692 https://reactome.org/PathwayBrowser/#/R-SSC-446692 IRAK1 binds to MYD88 within the IL1R complex IEA Sus scrofa A0A140TAK4 R-SSC-446694 https://reactome.org/PathwayBrowser/#/R-SSC-446694 IRAK4 phosphorylates IRAK1 IEA Sus scrofa A0A140TAK4 R-SSC-446701 https://reactome.org/PathwayBrowser/#/R-SSC-446701 IRAK4-activated IRAK1 autophosphorylates IEA Sus scrofa A0A140TAK4 R-SSC-446862 https://reactome.org/PathwayBrowser/#/R-SSC-446862 Hyperphosphorylated IRAK1 associates with TRAF6 IEA Sus scrofa A0A140TAK4 R-SSC-446868 https://reactome.org/PathwayBrowser/#/R-SSC-446868 The Interleukin 1 receptor complex binds Tollip IEA Sus scrofa A0A140TAK4 R-SSC-446894 https://reactome.org/PathwayBrowser/#/R-SSC-446894 TRAF6 binding leads to IRAK1:TRAF6 release IEA Sus scrofa A0A140TAK4 R-SSC-9604480 https://reactome.org/PathwayBrowser/#/R-SSC-9604480 NFkB complex translocates from the cytosol to the nucleus IEA Sus scrofa A0A140TAK4 R-SSC-9604487 https://reactome.org/PathwayBrowser/#/R-SSC-9604487 p-IRF7:p-IRF7 translocates to the nucleus IEA Sus scrofa A0A140TAL0 R-SSC-446221 https://reactome.org/PathwayBrowser/#/R-SSC-446221 GMPPB converts Mannose-1-phosphate to GDP-Mannose IEA Sus scrofa A0A140UHW4 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A140UHW4 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A140UHW4 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A140UHW4 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A140UHW4 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A140UHX3 R-RNO-2172666 https://reactome.org/PathwayBrowser/#/R-RNO-2172666 RB1 binds condensin II IEA Rattus norvegicus A0A140UHX3 R-RNO-2294580 https://reactome.org/PathwayBrowser/#/R-RNO-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Rattus norvegicus A0A140UHX3 R-RNO-2294590 https://reactome.org/PathwayBrowser/#/R-RNO-2294590 PLK1 binds phosphorylated condensin II complex IEA Rattus norvegicus A0A140UHX3 R-RNO-2294600 https://reactome.org/PathwayBrowser/#/R-RNO-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Rattus norvegicus A0A140UHX3 R-RNO-2429719 https://reactome.org/PathwayBrowser/#/R-RNO-2429719 MCPH1 sequesters condensin II IEA Rattus norvegicus A0A140UHX4 R-RNO-1632857 https://reactome.org/PathwayBrowser/#/R-RNO-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Rattus norvegicus A0A140UHX4 R-RNO-163664 https://reactome.org/PathwayBrowser/#/R-RNO-163664 AMP binds to gamma subunit of AMP kinase heterotrimer IEA Rattus norvegicus A0A140UHX4 R-RNO-164087 https://reactome.org/PathwayBrowser/#/R-RNO-164087 Phosphorylation of rChREBP(Ser 568) by rAMPK TAS Rattus norvegicus A0A140UHX4 R-RNO-164106 https://reactome.org/PathwayBrowser/#/R-RNO-164106 rLkb-1 (Stk-11) activates AMPK by phosphorylation TAS Rattus norvegicus A0A140UHX4 R-RNO-200421 https://reactome.org/PathwayBrowser/#/R-RNO-200421 Activation of cytosolic AMPK by phosphorylation IEA Rattus norvegicus A0A140UHX4 R-RNO-200423 https://reactome.org/PathwayBrowser/#/R-RNO-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Rattus norvegicus A0A140UHX4 R-RNO-380927 https://reactome.org/PathwayBrowser/#/R-RNO-380927 p-AMPK phosphorylates TSC1:TSC2 IEA Rattus norvegicus A0A140UHX4 R-RNO-380930 https://reactome.org/PathwayBrowser/#/R-RNO-380930 Phosphorylated AMPK binds AMP IEA Rattus norvegicus A0A140UHX4 R-RNO-380949 https://reactome.org/PathwayBrowser/#/R-RNO-380949 AMPK is dephosphorylated IEA Rattus norvegicus A0A140UHX4 R-RNO-447074 https://reactome.org/PathwayBrowser/#/R-RNO-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Rattus norvegicus A0A140UHX4 R-RNO-5631941 https://reactome.org/PathwayBrowser/#/R-RNO-5631941 SESN1,2,3 bind AMPK IEA Rattus norvegicus A0A140UHX4 R-RNO-5665868 https://reactome.org/PathwayBrowser/#/R-RNO-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Rattus norvegicus A0A140UHX4 R-RNO-5672008 https://reactome.org/PathwayBrowser/#/R-RNO-5672008 Thr-180 of ULK1 is phosphorylated IEA Rattus norvegicus A0A140UHX4 R-RNO-5672011 https://reactome.org/PathwayBrowser/#/R-RNO-5672011 p-AMPK:AMP binds the ULK complex IEA Rattus norvegicus A0A140UHX4 R-RNO-5673768 https://reactome.org/PathwayBrowser/#/R-RNO-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Rattus norvegicus A0A140UHX4 R-RNO-5675868 https://reactome.org/PathwayBrowser/#/R-RNO-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Rattus norvegicus A0A140UHX4 R-RNO-5679205 https://reactome.org/PathwayBrowser/#/R-RNO-5679205 ULK1 phosphorylates Beclin-1 IEA Rattus norvegicus A0A140UHX4 R-RNO-5679239 https://reactome.org/PathwayBrowser/#/R-RNO-5679239 ULK complex translocates to the ER IEA Rattus norvegicus A0A140UHX4 R-RNO-6805470 https://reactome.org/PathwayBrowser/#/R-RNO-6805470 AMPK phosphorylates TP53 IEA Rattus norvegicus A0A143ZUM0 R-PFA-3204303 https://reactome.org/PathwayBrowser/#/R-PFA-3204303 MRE11 binds cytosolic DNA IEA Plasmodium falciparum A0A143ZUM0 R-PFA-5693549 https://reactome.org/PathwayBrowser/#/R-PFA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Plasmodium falciparum A0A143ZUM0 R-PFA-75172 https://reactome.org/PathwayBrowser/#/R-PFA-75172 Formation of RAD50:MRE11 complex IEA Plasmodium falciparum A0A143ZVB5 R-PFA-429786 https://reactome.org/PathwayBrowser/#/R-PFA-429786 SGMS2 transfers phosphocholine onto ceramide IEA Plasmodium falciparum A0A143ZVB5 R-PFA-429798 https://reactome.org/PathwayBrowser/#/R-PFA-429798 SGMS1 transfers phosphocholine onto ceramide IEA Plasmodium falciparum A0A143ZVB5 R-PFA-8959462 https://reactome.org/PathwayBrowser/#/R-PFA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER IEA Plasmodium falciparum A0A143ZVC5 R-PFA-983140 https://reactome.org/PathwayBrowser/#/R-PFA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Plasmodium falciparum A0A143ZVC5 R-PFA-983147 https://reactome.org/PathwayBrowser/#/R-PFA-983147 Release of E3 from polyubiquitinated substrate IEA Plasmodium falciparum A0A143ZVC5 R-PFA-983156 https://reactome.org/PathwayBrowser/#/R-PFA-983156 Polyubiquitination of substrate IEA Plasmodium falciparum A0A143ZVC5 R-PFA-983157 https://reactome.org/PathwayBrowser/#/R-PFA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Plasmodium falciparum A0A143ZVI9 R-PFA-6798739 https://reactome.org/PathwayBrowser/#/R-PFA-6798739 Exocytosis of azurophil granule membrane proteins IEA Plasmodium falciparum A0A143ZVI9 R-PFA-6798745 https://reactome.org/PathwayBrowser/#/R-PFA-6798745 Exocytosis of tertiary granule lumen proteins IEA Plasmodium falciparum A0A143ZVI9 R-PFA-6798748 https://reactome.org/PathwayBrowser/#/R-PFA-6798748 Exocytosis of secretory granule lumen proteins IEA Plasmodium falciparum A0A143ZVI9 R-PFA-6798749 https://reactome.org/PathwayBrowser/#/R-PFA-6798749 Exocytosis of specific granule lumen proteins IEA Plasmodium falciparum A0A143ZVI9 R-PFA-6800434 https://reactome.org/PathwayBrowser/#/R-PFA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Plasmodium falciparum A0A143ZVJ8 R-PFA-6798739 https://reactome.org/PathwayBrowser/#/R-PFA-6798739 Exocytosis of azurophil granule membrane proteins IEA Plasmodium falciparum A0A143ZVJ8 R-PFA-6799350 https://reactome.org/PathwayBrowser/#/R-PFA-6799350 Exocytosis of specific granule membrane proteins IEA Plasmodium falciparum A0A143ZWA3 R-PFA-5681981 https://reactome.org/PathwayBrowser/#/R-PFA-5681981 ATG3 transfers LC3 from ATG7 to ATG3 IEA Plasmodium falciparum A0A143ZWA3 R-PFA-5682896 https://reactome.org/PathwayBrowser/#/R-PFA-5682896 LC3:ATG7 dimer binds ATG3 IEA Plasmodium falciparum A0A143ZWA3 R-PFA-5683593 https://reactome.org/PathwayBrowser/#/R-PFA-5683593 ATG7:ATG3:LC3 dissociates IEA Plasmodium falciparum A0A143ZWB4 R-PFA-376357 https://reactome.org/PathwayBrowser/#/R-PFA-376357 Vamp7 associated Lysosome to Plasma membrane transport IEA Plasmodium falciparum A0A143ZWE7 R-PFA-5690213 https://reactome.org/PathwayBrowser/#/R-PFA-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Plasmodium falciparum A0A143ZWE7 R-PFA-5690990 https://reactome.org/PathwayBrowser/#/R-PFA-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Plasmodium falciparum A0A143ZWE7 R-PFA-5690996 https://reactome.org/PathwayBrowser/#/R-PFA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Plasmodium falciparum A0A143ZWE7 R-PFA-6782204 https://reactome.org/PathwayBrowser/#/R-PFA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Plasmodium falciparum A0A143ZWE7 R-PFA-6782211 https://reactome.org/PathwayBrowser/#/R-PFA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Plasmodium falciparum A0A143ZWJ1 R-PFA-2130706 https://reactome.org/PathwayBrowser/#/R-PFA-2130706 MHC class II antigen processing IEA Plasmodium falciparum A0A143ZWJ1 R-PFA-6800434 https://reactome.org/PathwayBrowser/#/R-PFA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Plasmodium falciparum A0A143ZWJ6 R-PFA-5336466 https://reactome.org/PathwayBrowser/#/R-PFA-5336466 MRS2 transports Mg2+ from cytosol to mitochondrial matrix IEA Plasmodium falciparum A0A143ZX23 R-PFA-481007 https://reactome.org/PathwayBrowser/#/R-PFA-481007 Exocytosis of platelet alpha granule contents IEA Plasmodium falciparum A0A143ZXB3 R-PFA-6787623 https://reactome.org/PathwayBrowser/#/R-PFA-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Plasmodium falciparum A0A143ZXB3 R-PFA-6787642 https://reactome.org/PathwayBrowser/#/R-PFA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Plasmodium falciparum A0A143ZXR3 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum A0A143ZXR3 R-PFA-6798751 https://reactome.org/PathwayBrowser/#/R-PFA-6798751 Exocytosis of azurophil granule lumen proteins IEA Plasmodium falciparum A0A143ZXR3 R-PFA-6800434 https://reactome.org/PathwayBrowser/#/R-PFA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Plasmodium falciparum A0A143ZY16 R-PFA-3371422 https://reactome.org/PathwayBrowser/#/R-PFA-3371422 ATP hydrolysis by HSP70 IEA Plasmodium falciparum A0A143ZY16 R-PFA-3371503 https://reactome.org/PathwayBrowser/#/R-PFA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Plasmodium falciparum A0A143ZY16 R-PFA-3371590 https://reactome.org/PathwayBrowser/#/R-PFA-3371590 HSP70 binds to HSP40:nascent protein IEA Plasmodium falciparum A0A143ZY16 R-PFA-5251959 https://reactome.org/PathwayBrowser/#/R-PFA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Plasmodium falciparum A0A143ZY16 R-PFA-5690245 https://reactome.org/PathwayBrowser/#/R-PFA-5690245 p-T182 MAPKAPK5 binds DNAJB1 IEA Plasmodium falciparum A0A143ZY16 R-PFA-5690250 https://reactome.org/PathwayBrowser/#/R-PFA-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 IEA Plasmodium falciparum A0A143ZY25 R-PFA-6814086 https://reactome.org/PathwayBrowser/#/R-PFA-6814086 ARFRP1 recruits ARL1 to the TGN IEA Plasmodium falciparum A0A143ZY25 R-PFA-6814088 https://reactome.org/PathwayBrowser/#/R-PFA-6814088 SYS1 binds AcM-ARFRP1 IEA Plasmodium falciparum A0A143ZY29 R-PFA-927789 https://reactome.org/PathwayBrowser/#/R-PFA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Plasmodium falciparum A0A143ZY29 R-PFA-927889 https://reactome.org/PathwayBrowser/#/R-PFA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Plasmodium falciparum A0A143ZY34 R-PFA-8852129 https://reactome.org/PathwayBrowser/#/R-PFA-8852129 UBA1 conjugates ubiquitin to cytosolic E2 enzymes IEA Plasmodium falciparum A0A143ZY34 R-PFA-8852130 https://reactome.org/PathwayBrowser/#/R-PFA-8852130 UBA1 conjugates ubiquitin to nuclear E2 enzymes IEA Plasmodium falciparum A0A143ZY34 R-PFA-983140 https://reactome.org/PathwayBrowser/#/R-PFA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Plasmodium falciparum A0A143ZY34 R-PFA-983152 https://reactome.org/PathwayBrowser/#/R-PFA-983152 Transfer of ubiquitin from E1 to E2 IEA Plasmodium falciparum A0A143ZY34 R-PFA-983156 https://reactome.org/PathwayBrowser/#/R-PFA-983156 Polyubiquitination of substrate IEA Plasmodium falciparum A0A143ZY34 R-PFA-983157 https://reactome.org/PathwayBrowser/#/R-PFA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Plasmodium falciparum A0A143ZY58 R-PFA-1675883 https://reactome.org/PathwayBrowser/#/R-PFA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Plasmodium falciparum A0A143ZY58 R-PFA-1676152 https://reactome.org/PathwayBrowser/#/R-PFA-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Plasmodium falciparum A0A143ZY58 R-PFA-350769 https://reactome.org/PathwayBrowser/#/R-PFA-350769 trans-Golgi Network Coat Activation IEA Plasmodium falciparum A0A143ZY58 R-PFA-5623508 https://reactome.org/PathwayBrowser/#/R-PFA-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Plasmodium falciparum A0A143ZY58 R-PFA-6807868 https://reactome.org/PathwayBrowser/#/R-PFA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Plasmodium falciparum A0A143ZY58 R-PFA-6807872 https://reactome.org/PathwayBrowser/#/R-PFA-6807872 Active ARF recruits coatomer IEA Plasmodium falciparum A0A143ZY58 R-PFA-6811411 https://reactome.org/PathwayBrowser/#/R-PFA-6811411 GBF1 recruits ARF:GDP to the Golgi IEA Plasmodium falciparum A0A143ZY58 R-PFA-6811412 https://reactome.org/PathwayBrowser/#/R-PFA-6811412 Active ARF recruits coatomer to the Golgi IEA Plasmodium falciparum A0A143ZY58 R-PFA-6811414 https://reactome.org/PathwayBrowser/#/R-PFA-6811414 GBF1 stimulates nucleotide exchange on ARF IEA Plasmodium falciparum A0A143ZY58 R-PFA-6811417 https://reactome.org/PathwayBrowser/#/R-PFA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Plasmodium falciparum A0A143ZY58 R-PFA-6811418 https://reactome.org/PathwayBrowser/#/R-PFA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Plasmodium falciparum A0A143ZY58 R-PFA-8870499 https://reactome.org/PathwayBrowser/#/R-PFA-8870499 PLEKHA3,8 bind PI4P, ARF1 IEA Plasmodium falciparum A0A143ZY58 R-PFA-9845055 https://reactome.org/PathwayBrowser/#/R-PFA-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane IEA Plasmodium falciparum A0A143ZYC4 R-PFA-110246 https://reactome.org/PathwayBrowser/#/R-PFA-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Plasmodium falciparum A0A143ZYC4 R-PFA-110355 https://reactome.org/PathwayBrowser/#/R-PFA-110355 Displacement of MUTYH glycosylase by APEX1 at the AP site IEA Plasmodium falciparum A0A143ZYL5 R-PFA-914005 https://reactome.org/PathwayBrowser/#/R-PFA-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Plasmodium falciparum A0A143ZYL5 R-PFA-914006 https://reactome.org/PathwayBrowser/#/R-PFA-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Plasmodium falciparum A0A143ZYL5 R-PFA-914008 https://reactome.org/PathwayBrowser/#/R-PFA-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Plasmodium falciparum A0A143ZYL5 R-PFA-914017 https://reactome.org/PathwayBrowser/#/R-PFA-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Plasmodium falciparum A0A143ZYU5 R-PFA-9755306 https://reactome.org/PathwayBrowser/#/R-PFA-9755306 ub UBXN7 is degraded by the 26S proteasome IEA Plasmodium falciparum A0A143ZYU5 R-PFA-9758088 https://reactome.org/PathwayBrowser/#/R-PFA-9758088 UBXN7 binds VCP hexamer:UBF1:NPLOC4 IEA Plasmodium falciparum A0A143ZYZ7 R-PFA-110311 https://reactome.org/PathwayBrowser/#/R-PFA-110311 POLZ extends translesion synthesis IEA Plasmodium falciparum A0A143ZYZ7 R-PFA-110322 https://reactome.org/PathwayBrowser/#/R-PFA-110322 Formation of Pol zeta complex IEA Plasmodium falciparum A0A143ZYZ7 R-PFA-5652151 https://reactome.org/PathwayBrowser/#/R-PFA-5652151 REV1 recruits POLZ to (AP:Cyt)-DNA Template IEA Plasmodium falciparum A0A143ZYZ7 R-PFA-5655892 https://reactome.org/PathwayBrowser/#/R-PFA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Plasmodium falciparum A0A143ZYZ7 R-PFA-5655965 https://reactome.org/PathwayBrowser/#/R-PFA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Plasmodium falciparum A0A143ZYZ7 R-PFA-5656148 https://reactome.org/PathwayBrowser/#/R-PFA-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Plasmodium falciparum A0A143ZYZ7 R-PFA-5656158 https://reactome.org/PathwayBrowser/#/R-PFA-5656158 POLZ elongates POLI-incorporated dNMP IEA Plasmodium falciparum A0A143ZZ61 R-PFA-70494 https://reactome.org/PathwayBrowser/#/R-PFA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Plasmodium falciparum A0A143ZZ61 R-PFA-71660 https://reactome.org/PathwayBrowser/#/R-PFA-71660 Enolase dimers dehydrates 2PG IEA Plasmodium falciparum A0A143ZZC6 R-PFA-1675949 https://reactome.org/PathwayBrowser/#/R-PFA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Plasmodium falciparum A0A143ZZC6 R-PFA-1676177 https://reactome.org/PathwayBrowser/#/R-PFA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Plasmodium falciparum A0A143ZZC6 R-PFA-1855174 https://reactome.org/PathwayBrowser/#/R-PFA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Plasmodium falciparum A0A143ZZC6 R-PFA-1855218 https://reactome.org/PathwayBrowser/#/R-PFA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Plasmodium falciparum A0A143ZZG2 R-PFA-156808 https://reactome.org/PathwayBrowser/#/R-PFA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Plasmodium falciparum A0A143ZZG2 R-PFA-156823 https://reactome.org/PathwayBrowser/#/R-PFA-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Plasmodium falciparum A0A143ZZG2 R-PFA-157849 https://reactome.org/PathwayBrowser/#/R-PFA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Plasmodium falciparum A0A143ZZG2 R-PFA-1799332 https://reactome.org/PathwayBrowser/#/R-PFA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Plasmodium falciparum A0A143ZZG2 R-PFA-72621 https://reactome.org/PathwayBrowser/#/R-PFA-72621 Ribosomal scanning IEA Plasmodium falciparum A0A143ZZG2 R-PFA-72671 https://reactome.org/PathwayBrowser/#/R-PFA-72671 eIF5B:GTP is hydrolyzed and released IEA Plasmodium falciparum A0A143ZZG2 R-PFA-72672 https://reactome.org/PathwayBrowser/#/R-PFA-72672 The 60S subunit joins the translation initiation complex IEA Plasmodium falciparum A0A143ZZG2 R-PFA-72673 https://reactome.org/PathwayBrowser/#/R-PFA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Plasmodium falciparum A0A143ZZG2 R-PFA-72676 https://reactome.org/PathwayBrowser/#/R-PFA-72676 eIF3 and eIF1A bind to the 40S subunit IEA Plasmodium falciparum A0A143ZZG2 R-PFA-72691 https://reactome.org/PathwayBrowser/#/R-PFA-72691 Formation of the 43S pre-initiation complex IEA Plasmodium falciparum A0A143ZZG2 R-PFA-72697 https://reactome.org/PathwayBrowser/#/R-PFA-72697 Start codon recognition IEA Plasmodium falciparum A0A143ZZG2 R-PFA-927789 https://reactome.org/PathwayBrowser/#/R-PFA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Plasmodium falciparum A0A143ZZG2 R-PFA-927889 https://reactome.org/PathwayBrowser/#/R-PFA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Plasmodium falciparum A0A143ZZK9 R-PFA-936883 https://reactome.org/PathwayBrowser/#/R-PFA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Plasmodium falciparum A0A144A0T0 R-PFA-983140 https://reactome.org/PathwayBrowser/#/R-PFA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Plasmodium falciparum A0A144A0T0 R-PFA-983147 https://reactome.org/PathwayBrowser/#/R-PFA-983147 Release of E3 from polyubiquitinated substrate IEA Plasmodium falciparum A0A144A0T0 R-PFA-983156 https://reactome.org/PathwayBrowser/#/R-PFA-983156 Polyubiquitination of substrate IEA Plasmodium falciparum A0A144A0T0 R-PFA-983157 https://reactome.org/PathwayBrowser/#/R-PFA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Plasmodium falciparum A0A144A0U7 R-PFA-72670 https://reactome.org/PathwayBrowser/#/R-PFA-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Plasmodium falciparum A0A144A0U7 R-PFA-72722 https://reactome.org/PathwayBrowser/#/R-PFA-72722 eIF2 activation IEA Plasmodium falciparum A0A144A0V8 R-PFA-163296 https://reactome.org/PathwayBrowser/#/R-PFA-163296 Association of TFAM:mt promoter complex with POLRMT:TFB2M IEA Plasmodium falciparum A0A144A0W9 R-PFA-9794542 https://reactome.org/PathwayBrowser/#/R-PFA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Plasmodium falciparum A0A144A1B7 R-PFA-8875320 https://reactome.org/PathwayBrowser/#/R-PFA-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Plasmodium falciparum A0A144A1E5 R-PFA-983140 https://reactome.org/PathwayBrowser/#/R-PFA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Plasmodium falciparum A0A144A1E5 R-PFA-983147 https://reactome.org/PathwayBrowser/#/R-PFA-983147 Release of E3 from polyubiquitinated substrate IEA Plasmodium falciparum A0A144A1E5 R-PFA-983156 https://reactome.org/PathwayBrowser/#/R-PFA-983156 Polyubiquitination of substrate IEA Plasmodium falciparum A0A144A1E5 R-PFA-983157 https://reactome.org/PathwayBrowser/#/R-PFA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Plasmodium falciparum A0A144A1R5 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum A0A144A1R5 R-PFA-6798751 https://reactome.org/PathwayBrowser/#/R-PFA-6798751 Exocytosis of azurophil granule lumen proteins IEA Plasmodium falciparum A0A144A1R5 R-PFA-6800434 https://reactome.org/PathwayBrowser/#/R-PFA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Plasmodium falciparum A0A144A1Y0 R-PFA-111915 https://reactome.org/PathwayBrowser/#/R-PFA-111915 CAMK4 autophosphorylates IEA Plasmodium falciparum A0A144A1Y0 R-PFA-111956 https://reactome.org/PathwayBrowser/#/R-PFA-111956 Calmodulin activates Cam-PDE 1 IEA Plasmodium falciparum A0A144A1Y0 R-PFA-1497784 https://reactome.org/PathwayBrowser/#/R-PFA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Plasmodium falciparum A0A144A1Y0 R-PFA-1497796 https://reactome.org/PathwayBrowser/#/R-PFA-1497796 BH2 binding can lead to eNOS uncoupling IEA Plasmodium falciparum A0A144A1Y0 R-PFA-1497810 https://reactome.org/PathwayBrowser/#/R-PFA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Plasmodium falciparum A0A144A1Y0 R-PFA-1855153 https://reactome.org/PathwayBrowser/#/R-PFA-1855153 I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol IEA Plasmodium falciparum A0A144A1Y0 R-PFA-202111 https://reactome.org/PathwayBrowser/#/R-PFA-202111 AKT1 phosphorylates eNOS IEA Plasmodium falciparum A0A144A1Y0 R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum A0A144A1Y0 R-PFA-2730867 https://reactome.org/PathwayBrowser/#/R-PFA-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Plasmodium falciparum A0A144A1Y0 R-PFA-2730872 https://reactome.org/PathwayBrowser/#/R-PFA-2730872 Activation of Calcineurin IEA Plasmodium falciparum A0A144A1Y0 R-PFA-427910 https://reactome.org/PathwayBrowser/#/R-PFA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Plasmodium falciparum A0A144A1Y0 R-PFA-4332358 https://reactome.org/PathwayBrowser/#/R-PFA-4332358 Dissociation of CaM and CAMK2 autophosphorylation IEA Plasmodium falciparum A0A144A1Y0 R-PFA-4332359 https://reactome.org/PathwayBrowser/#/R-PFA-4332359 Active calmodulin binds CAMK2 IEA Plasmodium falciparum A0A144A1Y0 R-PFA-4332363 https://reactome.org/PathwayBrowser/#/R-PFA-4332363 Autophosphorylation and activation of CAMK2 IEA Plasmodium falciparum A0A144A1Y0 R-PFA-4551465 https://reactome.org/PathwayBrowser/#/R-PFA-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Plasmodium falciparum A0A144A1Y0 R-PFA-482772 https://reactome.org/PathwayBrowser/#/R-PFA-482772 Release of platelet cytosolic components IEA Plasmodium falciparum A0A144A1Y0 R-PFA-6800434 https://reactome.org/PathwayBrowser/#/R-PFA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Plasmodium falciparum A0A144A1Y0 R-PFA-9619376 https://reactome.org/PathwayBrowser/#/R-PFA-9619376 CAMK1 binds calmodulin IEA Plasmodium falciparum A0A144A2J9 R-PFA-3371503 https://reactome.org/PathwayBrowser/#/R-PFA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Plasmodium falciparum A0A144A2J9 R-PFA-5618085 https://reactome.org/PathwayBrowser/#/R-PFA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Plasmodium falciparum A0A144A2J9 R-PFA-5618098 https://reactome.org/PathwayBrowser/#/R-PFA-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Plasmodium falciparum A0A144A2J9 R-PFA-5618105 https://reactome.org/PathwayBrowser/#/R-PFA-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Plasmodium falciparum A0A144A2J9 R-PFA-5618107 https://reactome.org/PathwayBrowser/#/R-PFA-5618107 ATP binding to HSP90 triggers conformation change IEA Plasmodium falciparum A0A144A2J9 R-PFA-5618110 https://reactome.org/PathwayBrowser/#/R-PFA-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Plasmodium falciparum A0A144A2N8 R-PFA-6791222 https://reactome.org/PathwayBrowser/#/R-PFA-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Plasmodium falciparum A0A144A2S8 R-PFA-6782204 https://reactome.org/PathwayBrowser/#/R-PFA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Plasmodium falciparum A0A144A2S8 R-PFA-6782208 https://reactome.org/PathwayBrowser/#/R-PFA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Plasmodium falciparum A0A144A2S8 R-PFA-6782211 https://reactome.org/PathwayBrowser/#/R-PFA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Plasmodium falciparum A0A144A2S8 R-PFA-9794542 https://reactome.org/PathwayBrowser/#/R-PFA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Plasmodium falciparum A0A144A308 R-PFA-429714 https://reactome.org/PathwayBrowser/#/R-PFA-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Plasmodium falciparum A0A144A3E6 R-PFA-5676966 https://reactome.org/PathwayBrowser/#/R-PFA-5676966 PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp IEA Plasmodium falciparum A0A144A3J8 R-PFA-983140 https://reactome.org/PathwayBrowser/#/R-PFA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Plasmodium falciparum A0A144A3J8 R-PFA-983147 https://reactome.org/PathwayBrowser/#/R-PFA-983147 Release of E3 from polyubiquitinated substrate IEA Plasmodium falciparum A0A144A3J8 R-PFA-983156 https://reactome.org/PathwayBrowser/#/R-PFA-983156 Polyubiquitination of substrate IEA Plasmodium falciparum A0A144A3J8 R-PFA-983157 https://reactome.org/PathwayBrowser/#/R-PFA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Plasmodium falciparum A0A144A3N9 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum A0A144A3N9 R-PFA-6798751 https://reactome.org/PathwayBrowser/#/R-PFA-6798751 Exocytosis of azurophil granule lumen proteins IEA Plasmodium falciparum A0A144A3N9 R-PFA-6800434 https://reactome.org/PathwayBrowser/#/R-PFA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Plasmodium falciparum A0A144A4T0 R-PFA-3782655 https://reactome.org/PathwayBrowser/#/R-PFA-3782655 HDAC10 deacetylates histone IEA Plasmodium falciparum A0A164D380 R-CEL-8854329 https://reactome.org/PathwayBrowser/#/R-CEL-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Caenorhabditis elegans A0A164D3G3 R-CEL-72180 https://reactome.org/PathwayBrowser/#/R-CEL-72180 Cleavage of mRNA at the 3'-end IEA Caenorhabditis elegans A0A164D3G3 R-CEL-72185 https://reactome.org/PathwayBrowser/#/R-CEL-72185 mRNA polyadenylation IEA Caenorhabditis elegans A0A164D3G3 R-CEL-72231 https://reactome.org/PathwayBrowser/#/R-CEL-72231 Formation of the Cleavage and Polyadenylation Complex IEA Caenorhabditis elegans A0A164D3G3 R-CEL-77589 https://reactome.org/PathwayBrowser/#/R-CEL-77589 Recognition of AAUAAA sequence by CPSF IEA Caenorhabditis elegans A0A164D3G3 R-CEL-77590 https://reactome.org/PathwayBrowser/#/R-CEL-77590 Recruitment of CstF to the CPSF Bound Pre-mRNA IEA Caenorhabditis elegans A0A164D3G3 R-CEL-77591 https://reactome.org/PathwayBrowser/#/R-CEL-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Caenorhabditis elegans A0A164D3G3 R-CEL-77592 https://reactome.org/PathwayBrowser/#/R-CEL-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Caenorhabditis elegans A0A164D3G3 R-CEL-77593 https://reactome.org/PathwayBrowser/#/R-CEL-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Caenorhabditis elegans A0A165EAY6 R-GGA-1454916 https://reactome.org/PathwayBrowser/#/R-GGA-1454916 The ABCC family mediates organic anion transport IEA Gallus gallus A0A165EAY6 R-GGA-429157 https://reactome.org/PathwayBrowser/#/R-GGA-429157 ABCC4 accumulation of dense granule contents IEA Gallus gallus A0A165EAY6 R-GGA-9750546 https://reactome.org/PathwayBrowser/#/R-GGA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus A0A165EAY6 R-GGA-9753283 https://reactome.org/PathwayBrowser/#/R-GGA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus A0A165EAY6 R-GGA-9753284 https://reactome.org/PathwayBrowser/#/R-GGA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Gallus gallus A0A167VDT2 R-GGA-6799777 https://reactome.org/PathwayBrowser/#/R-GGA-6799777 TP53 family members bind PPP1R13B or TP53BP2 IEA Gallus gallus A0A172PWX7 R-GGA-374787 https://reactome.org/PathwayBrowser/#/R-GGA-374787 GPCR neuropeptide receptor binds neuropeptides B and W IEA Gallus gallus A0A172PWX7 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A172PWX7 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A172PWX7 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A181 R-DRE-420243 https://reactome.org/PathwayBrowser/#/R-DRE-420243 GHRH receptor binds GHRH IEA Danio rerio A0A182 R-DRE-420243 https://reactome.org/PathwayBrowser/#/R-DRE-420243 GHRH receptor binds GHRH IEA Danio rerio A0A183 R-HSA-6814298 https://reactome.org/PathwayBrowser/#/R-HSA-6814298 Late envelope proteins bind cornified envelope:CDSN TAS Homo sapiens A0A183 R-HSA-6814387 https://reactome.org/PathwayBrowser/#/R-HSA-6814387 CASP14 cleaves filaggrin TAS Homo sapiens A0A183 R-HSA-6814764 https://reactome.org/PathwayBrowser/#/R-HSA-6814764 Plasma membrane resorption TAS Homo sapiens A0A193KX02 R-DRE-8955010 https://reactome.org/PathwayBrowser/#/R-DRE-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Danio rerio A0A1B0GR10 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A1B0GRJ4 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A1B0GRL1 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A1B0GS71 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A1B0GS75 R-MMU-199518 https://reactome.org/PathwayBrowser/#/R-MMU-199518 C3d-complexed antigen binds to complement receptor IEA Mus musculus A0A1B0GSA0 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A1B0GSA9 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A1B0GSH7 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A1B0GSS6 R-MMU-975040 https://reactome.org/PathwayBrowser/#/R-MMU-975040 KRAB-ZNF / KAP Interaction IEA Mus musculus A0A1B0GT06 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A1B0GT64 R-MMU-975040 https://reactome.org/PathwayBrowser/#/R-MMU-975040 KRAB-ZNF / KAP Interaction IEA Mus musculus A0A1B0GT64 R-MMU-9842833 https://reactome.org/PathwayBrowser/#/R-MMU-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Mus musculus A0A1B0GWP1 R-RNO-2046088 https://reactome.org/PathwayBrowser/#/R-RNO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Rattus norvegicus A0A1B0GWP1 R-RNO-2046094 https://reactome.org/PathwayBrowser/#/R-RNO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Rattus norvegicus A0A1B0GWP1 R-RNO-548800 https://reactome.org/PathwayBrowser/#/R-RNO-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Rattus norvegicus A0A1B0GWQ8 R-RNO-5690790 https://reactome.org/PathwayBrowser/#/R-RNO-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Rattus norvegicus A0A1B0GWR9 R-RNO-6798747 https://reactome.org/PathwayBrowser/#/R-RNO-6798747 Exocytosis of tertiary granule membrane proteins IEA Rattus norvegicus A0A1B0GWR9 R-RNO-6799350 https://reactome.org/PathwayBrowser/#/R-RNO-6799350 Exocytosis of specific granule membrane proteins IEA Rattus norvegicus A0A1B0GWR9 R-RNO-939763 https://reactome.org/PathwayBrowser/#/R-RNO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Rattus norvegicus A0A1B0GWR9 R-RNO-947591 https://reactome.org/PathwayBrowser/#/R-RNO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Rattus norvegicus A0A1B0GWS0 R-RNO-210426 https://reactome.org/PathwayBrowser/#/R-RNO-210426 Glutamate synaptic vesicle docking and priming IEA Rattus norvegicus A0A1B0GWS0 R-RNO-210430 https://reactome.org/PathwayBrowser/#/R-RNO-210430 Release of L-Glutamate at the synapse IEA Rattus norvegicus A0A1B0GWS0 R-RNO-372505 https://reactome.org/PathwayBrowser/#/R-RNO-372505 Acetylcholine synaptic vesicle docking and priming IEA Rattus norvegicus A0A1B0GWS0 R-RNO-372529 https://reactome.org/PathwayBrowser/#/R-RNO-372529 Release of acetylcholine at the synapse IEA Rattus norvegicus A0A1B0GWS0 R-RNO-374899 https://reactome.org/PathwayBrowser/#/R-RNO-374899 Release of noradrenaline at the synapse IEA Rattus norvegicus A0A1B0GWS0 R-RNO-374922 https://reactome.org/PathwayBrowser/#/R-RNO-374922 Noradrenalin synaptic vesicle docking and priming IEA Rattus norvegicus A0A1B0GWS0 R-RNO-380574 https://reactome.org/PathwayBrowser/#/R-RNO-380574 Dopamine synaptic vesicle docking and priming IEA Rattus norvegicus A0A1B0GWS0 R-RNO-380869 https://reactome.org/PathwayBrowser/#/R-RNO-380869 Release of docked dopamine loaded synaptic vesicle IEA Rattus norvegicus A0A1B0GWS0 R-RNO-380901 https://reactome.org/PathwayBrowser/#/R-RNO-380901 Release of docked serotonin loaded synaptic vesicle IEA Rattus norvegicus A0A1B0GWS0 R-RNO-380905 https://reactome.org/PathwayBrowser/#/R-RNO-380905 Serotonin loaded synaptic vesicle docking and priming IEA Rattus norvegicus A0A1B0GWS0 R-RNO-388824 https://reactome.org/PathwayBrowser/#/R-RNO-388824 PTPRF, PTPRS, PTPRD bind Liprins IEA Rattus norvegicus A0A1B0GWU1 R-RNO-8952618 https://reactome.org/PathwayBrowser/#/R-RNO-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A1B0GWU1 R-RNO-8952620 https://reactome.org/PathwayBrowser/#/R-RNO-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A1B0GWU1 R-RNO-8955241 https://reactome.org/PathwayBrowser/#/R-RNO-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Rattus norvegicus A0A1B0GWU1 R-RNO-8955289 https://reactome.org/PathwayBrowser/#/R-RNO-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Rattus norvegicus A0A1B0GWU1 R-RNO-8956040 https://reactome.org/PathwayBrowser/#/R-RNO-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Rattus norvegicus A0A1B0GWU1 R-RNO-8956200 https://reactome.org/PathwayBrowser/#/R-RNO-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Rattus norvegicus A0A1B0GWU1 R-RNO-983140 https://reactome.org/PathwayBrowser/#/R-RNO-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Rattus norvegicus A0A1B0GWU1 R-RNO-983147 https://reactome.org/PathwayBrowser/#/R-RNO-983147 Release of E3 from polyubiquitinated substrate IEA Rattus norvegicus A0A1B0GWU1 R-RNO-983156 https://reactome.org/PathwayBrowser/#/R-RNO-983156 Polyubiquitination of substrate IEA Rattus norvegicus A0A1B0GWU1 R-RNO-983157 https://reactome.org/PathwayBrowser/#/R-RNO-983157 Interaction of E3 with substrate and E2-Ub complex IEA Rattus norvegicus A0A1B0GWY3 R-RNO-5205661 https://reactome.org/PathwayBrowser/#/R-RNO-5205661 Pink1 is recruited from the cytoplasm to the mitochondria IEA Rattus norvegicus A0A1B0GWY7 R-RNO-5357780 https://reactome.org/PathwayBrowser/#/R-RNO-5357780 TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) IEA Rattus norvegicus A0A1B0GWY7 R-RNO-5634221 https://reactome.org/PathwayBrowser/#/R-RNO-5634221 TRAF1 binds TRAF2 within TNFR1 signaling complex IEA Rattus norvegicus A0A1B0GWY7 R-RNO-5634228 https://reactome.org/PathwayBrowser/#/R-RNO-5634228 TRAF1 is cleaved by caspases IEA Rattus norvegicus A0A1B0GWY7 R-RNO-5693108 https://reactome.org/PathwayBrowser/#/R-RNO-5693108 TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains IEA Rattus norvegicus A0A1B1X468 R-CFA-164832 https://reactome.org/PathwayBrowser/#/R-CFA-164832 ATPase synthesizes ATP IEA Canis familiaris A0A1B1X468 R-CFA-164834 https://reactome.org/PathwayBrowser/#/R-CFA-164834 Enzyme-bound ATP is released IEA Canis familiaris A0A1B1X468 R-CFA-164840 https://reactome.org/PathwayBrowser/#/R-CFA-164840 ADP and Pi bind to ATPase IEA Canis familiaris A0A1B1X468 R-CFA-8949580 https://reactome.org/PathwayBrowser/#/R-CFA-8949580 F1Fo ATP synthase dimerizes IEA Canis familiaris A0A1B1X468 R-CFA-8986181 https://reactome.org/PathwayBrowser/#/R-CFA-8986181 PITRM1 proteolyzes mitochondrial targeting peptides (presequences) IEA Canis familiaris A0A1B1X468 R-CFA-9838035 https://reactome.org/PathwayBrowser/#/R-CFA-9838035 CLPXP binds mitochondrial matrix proteins IEA Canis familiaris A0A1B1X468 R-CFA-9838081 https://reactome.org/PathwayBrowser/#/R-CFA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Canis familiaris A0A1B1X468 R-CFA-9838093 https://reactome.org/PathwayBrowser/#/R-CFA-9838093 LONP1 binds mitochondrial matrix proteins IEA Canis familiaris A0A1B1X468 R-CFA-9838289 https://reactome.org/PathwayBrowser/#/R-CFA-9838289 CLPXP degrades mitochondrial matrix proteins IEA Canis familiaris A0A1B1X469 R-CFA-164832 https://reactome.org/PathwayBrowser/#/R-CFA-164832 ATPase synthesizes ATP IEA Canis familiaris A0A1B1X469 R-CFA-164834 https://reactome.org/PathwayBrowser/#/R-CFA-164834 Enzyme-bound ATP is released IEA Canis familiaris A0A1B1X469 R-CFA-164840 https://reactome.org/PathwayBrowser/#/R-CFA-164840 ADP and Pi bind to ATPase IEA Canis familiaris A0A1B1X469 R-CFA-8949580 https://reactome.org/PathwayBrowser/#/R-CFA-8949580 F1Fo ATP synthase dimerizes IEA Canis familiaris A0A1B1X469 R-CFA-9838035 https://reactome.org/PathwayBrowser/#/R-CFA-9838035 CLPXP binds mitochondrial matrix proteins IEA Canis familiaris A0A1B1X469 R-CFA-9838081 https://reactome.org/PathwayBrowser/#/R-CFA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Canis familiaris A0A1B1X469 R-CFA-9838093 https://reactome.org/PathwayBrowser/#/R-CFA-9838093 LONP1 binds mitochondrial matrix proteins IEA Canis familiaris A0A1B1X469 R-CFA-9838289 https://reactome.org/PathwayBrowser/#/R-CFA-9838289 CLPXP degrades mitochondrial matrix proteins IEA Canis familiaris A0A1B1X469 R-CFA-9839105 https://reactome.org/PathwayBrowser/#/R-CFA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Canis familiaris A0A1B1X469 R-CFA-9839149 https://reactome.org/PathwayBrowser/#/R-CFA-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Canis familiaris A0A1B2TT36 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A1B2TT36 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A1B2TT36 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A1B2TT36 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A1B2TT36 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A1B2TT36 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A1B2TT36 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A1B8XTI8 R-XTR-8931858 https://reactome.org/PathwayBrowser/#/R-XTR-8931858 ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB IEA Xenopus tropicalis A0A1B8XVB0 R-XTR-6787811 https://reactome.org/PathwayBrowser/#/R-XTR-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Xenopus tropicalis A0A1B8XVB0 R-XTR-9033235 https://reactome.org/PathwayBrowser/#/R-XTR-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Xenopus tropicalis A0A1B8XVB0 R-XTR-9033236 https://reactome.org/PathwayBrowser/#/R-XTR-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Xenopus tropicalis A0A1B8XW41 R-XTR-1605797 https://reactome.org/PathwayBrowser/#/R-XTR-1605797 SMPD1 hydrolyzes SPHM IEA Xenopus tropicalis A0A1B8XX76 R-XTR-374787 https://reactome.org/PathwayBrowser/#/R-XTR-374787 GPCR neuropeptide receptor binds neuropeptides B and W IEA Xenopus tropicalis A0A1B8XX76 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis A0A1B8XX76 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis A0A1B8XX76 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis A0A1B8XXC7 R-XTR-5694409 https://reactome.org/PathwayBrowser/#/R-XTR-5694409 Nucleotide exchange on RAB1 IEA Xenopus tropicalis A0A1B8XYB1 R-XTR-9013004 https://reactome.org/PathwayBrowser/#/R-XTR-9013004 RHOA binds effectors at the ER membrane IEA Xenopus tropicalis A0A1B8Y089 R-XTR-427645 https://reactome.org/PathwayBrowser/#/R-XTR-427645 SLC34A3 cotransports Pi, 2Na+ IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-176700 https://reactome.org/PathwayBrowser/#/R-XTR-176700 Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-181450 https://reactome.org/PathwayBrowser/#/R-XTR-181450 Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-212222 https://reactome.org/PathwayBrowser/#/R-XTR-212222 PRC2 recruits DNA methyltransferases IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-212252 https://reactome.org/PathwayBrowser/#/R-XTR-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-212263 https://reactome.org/PathwayBrowser/#/R-XTR-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-212269 https://reactome.org/PathwayBrowser/#/R-XTR-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-2172678 https://reactome.org/PathwayBrowser/#/R-XTR-2172678 PHF8 demethylates histone H4K20me1 IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-2301205 https://reactome.org/PathwayBrowser/#/R-XTR-2301205 SETD8 monomethylates histone H4 IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-3222593 https://reactome.org/PathwayBrowser/#/R-XTR-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-3229089 https://reactome.org/PathwayBrowser/#/R-XTR-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-3240295 https://reactome.org/PathwayBrowser/#/R-XTR-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-3318415 https://reactome.org/PathwayBrowser/#/R-XTR-3318415 ATF2 acetylates histone H2B, H4 IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-3662335 https://reactome.org/PathwayBrowser/#/R-XTR-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-3785711 https://reactome.org/PathwayBrowser/#/R-XTR-3785711 Telomere shortening during replicative exhaustion IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-3788745 https://reactome.org/PathwayBrowser/#/R-XTR-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-3788748 https://reactome.org/PathwayBrowser/#/R-XTR-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-427337 https://reactome.org/PathwayBrowser/#/R-XTR-427337 MBD2 binds methylcytosine in chromatin IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-5578742 https://reactome.org/PathwayBrowser/#/R-XTR-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-5690080 https://reactome.org/PathwayBrowser/#/R-XTR-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-5696960 https://reactome.org/PathwayBrowser/#/R-XTR-5696960 USP49 deubiquitinates H2B IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-73718 https://reactome.org/PathwayBrowser/#/R-XTR-73718 UBF-1 Binds rDNA Promoter IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-8936481 https://reactome.org/PathwayBrowser/#/R-XTR-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-8936584 https://reactome.org/PathwayBrowser/#/R-XTR-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-8936608 https://reactome.org/PathwayBrowser/#/R-XTR-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-8936621 https://reactome.org/PathwayBrowser/#/R-XTR-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-8937016 https://reactome.org/PathwayBrowser/#/R-XTR-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-8937022 https://reactome.org/PathwayBrowser/#/R-XTR-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-8937050 https://reactome.org/PathwayBrowser/#/R-XTR-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-8937113 https://reactome.org/PathwayBrowser/#/R-XTR-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-8942099 https://reactome.org/PathwayBrowser/#/R-XTR-8942099 RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-8942101 https://reactome.org/PathwayBrowser/#/R-XTR-8942101 RNF20:RNF40 monoubiquitinates Histone H2B IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-9011949 https://reactome.org/PathwayBrowser/#/R-XTR-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-9011952 https://reactome.org/PathwayBrowser/#/R-XTR-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-9011981 https://reactome.org/PathwayBrowser/#/R-XTR-9011981 EP300 is recruited to MYC and BCL2 genes IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-9011983 https://reactome.org/PathwayBrowser/#/R-XTR-9011983 Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-9011984 https://reactome.org/PathwayBrowser/#/R-XTR-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-9011985 https://reactome.org/PathwayBrowser/#/R-XTR-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-9012000 https://reactome.org/PathwayBrowser/#/R-XTR-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-9629195 https://reactome.org/PathwayBrowser/#/R-XTR-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-9629216 https://reactome.org/PathwayBrowser/#/R-XTR-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-9749197 https://reactome.org/PathwayBrowser/#/R-XTR-9749197 ORC1 binds to H4K20me2 IEA Xenopus tropicalis A0A1B8Y0L0 R-XTR-9843118 https://reactome.org/PathwayBrowser/#/R-XTR-9843118 RXRA binds ligands IEA Xenopus tropicalis A0A1B8Y0M8 R-XTR-6787533 https://reactome.org/PathwayBrowser/#/R-XTR-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Xenopus tropicalis A0A1B8Y1F7 R-XTR-8953013 https://reactome.org/PathwayBrowser/#/R-XTR-8953013 E2F7 binds E2F8 IEA Xenopus tropicalis A0A1B8Y1F7 R-XTR-8953037 https://reactome.org/PathwayBrowser/#/R-XTR-8953037 E2F8 forms homodimers IEA Xenopus tropicalis A0A1B8Y2F0 R-XTR-8875318 https://reactome.org/PathwayBrowser/#/R-XTR-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Xenopus tropicalis A0A1B8Y2F0 R-XTR-8876188 https://reactome.org/PathwayBrowser/#/R-XTR-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Xenopus tropicalis A0A1B8Y2F0 R-XTR-8876190 https://reactome.org/PathwayBrowser/#/R-XTR-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Xenopus tropicalis A0A1B8Y2F0 R-XTR-8876191 https://reactome.org/PathwayBrowser/#/R-XTR-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Xenopus tropicalis A0A1B8Y2F0 R-XTR-8876615 https://reactome.org/PathwayBrowser/#/R-XTR-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Xenopus tropicalis A0A1B8Y2F0 R-XTR-8877612 https://reactome.org/PathwayBrowser/#/R-XTR-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Xenopus tropicalis A0A1B8Y313 R-XTR-192422 https://reactome.org/PathwayBrowser/#/R-XTR-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Xenopus tropicalis A0A1B8Y313 R-XTR-192434 https://reactome.org/PathwayBrowser/#/R-XTR-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Xenopus tropicalis A0A1B8Y313 R-XTR-975593 https://reactome.org/PathwayBrowser/#/R-XTR-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Xenopus tropicalis A0A1B8Y3D5 R-XTR-481009 https://reactome.org/PathwayBrowser/#/R-XTR-481009 Exocytosis of platelet dense granule content IEA Xenopus tropicalis A0A1B8Y3G3 R-XTR-163217 https://reactome.org/PathwayBrowser/#/R-XTR-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Xenopus tropicalis A0A1B8Y3G3 R-XTR-6798739 https://reactome.org/PathwayBrowser/#/R-XTR-6798739 Exocytosis of azurophil granule membrane proteins IEA Xenopus tropicalis A0A1B8Y3G3 R-XTR-6799202 https://reactome.org/PathwayBrowser/#/R-XTR-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Xenopus tropicalis A0A1B8Y3J5 R-XTR-428052 https://reactome.org/PathwayBrowser/#/R-XTR-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Xenopus tropicalis A0A1B8Y467 R-XTR-6798743 https://reactome.org/PathwayBrowser/#/R-XTR-6798743 Exocytosis of secretory granule membrane proteins IEA Xenopus tropicalis A0A1B8Y467 R-XTR-6798747 https://reactome.org/PathwayBrowser/#/R-XTR-6798747 Exocytosis of tertiary granule membrane proteins IEA Xenopus tropicalis A0A1B8Y4I1 R-XTR-5251942 https://reactome.org/PathwayBrowser/#/R-XTR-5251942 Hikeshi binds HSP70s:ATP IEA Xenopus tropicalis A0A1B8Y4I1 R-XTR-5251955 https://reactome.org/PathwayBrowser/#/R-XTR-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Xenopus tropicalis A0A1B8Y4I1 R-XTR-5251959 https://reactome.org/PathwayBrowser/#/R-XTR-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Xenopus tropicalis A0A1B8Y4I1 R-XTR-5252041 https://reactome.org/PathwayBrowser/#/R-XTR-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Xenopus tropicalis A0A1B8Y4I1 R-XTR-5252079 https://reactome.org/PathwayBrowser/#/R-XTR-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Xenopus tropicalis A0A1B8Y4Y6 R-XTR-8936442 https://reactome.org/PathwayBrowser/#/R-XTR-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Xenopus tropicalis A0A1B8Y6G2 R-XTR-8952630 https://reactome.org/PathwayBrowser/#/R-XTR-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex IEA Xenopus tropicalis A0A1B8Y6G2 R-XTR-8952631 https://reactome.org/PathwayBrowser/#/R-XTR-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Xenopus tropicalis A0A1B8Y6G2 R-XTR-8955241 https://reactome.org/PathwayBrowser/#/R-XTR-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Xenopus tropicalis A0A1B8Y6G2 R-XTR-8955289 https://reactome.org/PathwayBrowser/#/R-XTR-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Xenopus tropicalis A0A1B8Y6G2 R-XTR-8956040 https://reactome.org/PathwayBrowser/#/R-XTR-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Xenopus tropicalis A0A1B8Y6G2 R-XTR-983140 https://reactome.org/PathwayBrowser/#/R-XTR-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Xenopus tropicalis A0A1B8Y6G2 R-XTR-983147 https://reactome.org/PathwayBrowser/#/R-XTR-983147 Release of E3 from polyubiquitinated substrate IEA Xenopus tropicalis A0A1B8Y6G2 R-XTR-983156 https://reactome.org/PathwayBrowser/#/R-XTR-983156 Polyubiquitination of substrate IEA Xenopus tropicalis A0A1B8Y6G2 R-XTR-983157 https://reactome.org/PathwayBrowser/#/R-XTR-983157 Interaction of E3 with substrate and E2-Ub complex IEA Xenopus tropicalis A0A1B8Y6Y7 R-XTR-444171 https://reactome.org/PathwayBrowser/#/R-XTR-444171 Receptor FFAR2 binds carboxylates IEA Xenopus tropicalis A0A1B8Y6Y7 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis A0A1B8Y6Y7 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis A0A1B8Y7C6 R-XTR-1964505 https://reactome.org/PathwayBrowser/#/R-XTR-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Xenopus tropicalis A0A1B8Y828 R-XTR-176700 https://reactome.org/PathwayBrowser/#/R-XTR-176700 Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure IEA Xenopus tropicalis A0A1B8Y828 R-XTR-181450 https://reactome.org/PathwayBrowser/#/R-XTR-181450 Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure IEA Xenopus tropicalis A0A1B8Y828 R-XTR-212222 https://reactome.org/PathwayBrowser/#/R-XTR-212222 PRC2 recruits DNA methyltransferases IEA Xenopus tropicalis A0A1B8Y828 R-XTR-212252 https://reactome.org/PathwayBrowser/#/R-XTR-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Xenopus tropicalis A0A1B8Y828 R-XTR-212263 https://reactome.org/PathwayBrowser/#/R-XTR-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Xenopus tropicalis A0A1B8Y828 R-XTR-212269 https://reactome.org/PathwayBrowser/#/R-XTR-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Xenopus tropicalis A0A1B8Y828 R-XTR-2172678 https://reactome.org/PathwayBrowser/#/R-XTR-2172678 PHF8 demethylates histone H4K20me1 IEA Xenopus tropicalis A0A1B8Y828 R-XTR-2301205 https://reactome.org/PathwayBrowser/#/R-XTR-2301205 SETD8 monomethylates histone H4 IEA Xenopus tropicalis A0A1B8Y828 R-XTR-3222593 https://reactome.org/PathwayBrowser/#/R-XTR-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Xenopus tropicalis A0A1B8Y828 R-XTR-3229089 https://reactome.org/PathwayBrowser/#/R-XTR-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Xenopus tropicalis A0A1B8Y828 R-XTR-3240295 https://reactome.org/PathwayBrowser/#/R-XTR-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Xenopus tropicalis A0A1B8Y828 R-XTR-3662335 https://reactome.org/PathwayBrowser/#/R-XTR-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Xenopus tropicalis A0A1B8Y828 R-XTR-3785711 https://reactome.org/PathwayBrowser/#/R-XTR-3785711 Telomere shortening during replicative exhaustion IEA Xenopus tropicalis A0A1B8Y828 R-XTR-3788745 https://reactome.org/PathwayBrowser/#/R-XTR-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Xenopus tropicalis A0A1B8Y828 R-XTR-3788748 https://reactome.org/PathwayBrowser/#/R-XTR-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Xenopus tropicalis A0A1B8Y828 R-XTR-427337 https://reactome.org/PathwayBrowser/#/R-XTR-427337 MBD2 binds methylcytosine in chromatin IEA Xenopus tropicalis A0A1B8Y828 R-XTR-5205820 https://reactome.org/PathwayBrowser/#/R-XTR-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Xenopus tropicalis A0A1B8Y828 R-XTR-5205867 https://reactome.org/PathwayBrowser/#/R-XTR-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Xenopus tropicalis A0A1B8Y828 R-XTR-5216234 https://reactome.org/PathwayBrowser/#/R-XTR-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Xenopus tropicalis A0A1B8Y828 R-XTR-5229203 https://reactome.org/PathwayBrowser/#/R-XTR-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Xenopus tropicalis A0A1B8Y828 R-XTR-5578742 https://reactome.org/PathwayBrowser/#/R-XTR-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Xenopus tropicalis A0A1B8Y828 R-XTR-5690080 https://reactome.org/PathwayBrowser/#/R-XTR-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Xenopus tropicalis A0A1B8Y828 R-XTR-5690157 https://reactome.org/PathwayBrowser/#/R-XTR-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Xenopus tropicalis A0A1B8Y828 R-XTR-5690790 https://reactome.org/PathwayBrowser/#/R-XTR-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Xenopus tropicalis A0A1B8Y828 R-XTR-5691381 https://reactome.org/PathwayBrowser/#/R-XTR-5691381 MYSM1 deubiquitinates Histone H2A IEA Xenopus tropicalis A0A1B8Y828 R-XTR-5691411 https://reactome.org/PathwayBrowser/#/R-XTR-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Xenopus tropicalis A0A1B8Y828 R-XTR-73718 https://reactome.org/PathwayBrowser/#/R-XTR-73718 UBF-1 Binds rDNA Promoter IEA Xenopus tropicalis A0A1B8Y828 R-XTR-8936481 https://reactome.org/PathwayBrowser/#/R-XTR-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Xenopus tropicalis A0A1B8Y828 R-XTR-8936584 https://reactome.org/PathwayBrowser/#/R-XTR-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Xenopus tropicalis A0A1B8Y828 R-XTR-8936608 https://reactome.org/PathwayBrowser/#/R-XTR-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Xenopus tropicalis A0A1B8Y828 R-XTR-8936621 https://reactome.org/PathwayBrowser/#/R-XTR-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Xenopus tropicalis A0A1B8Y828 R-XTR-8937016 https://reactome.org/PathwayBrowser/#/R-XTR-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Xenopus tropicalis A0A1B8Y828 R-XTR-8937022 https://reactome.org/PathwayBrowser/#/R-XTR-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Xenopus tropicalis A0A1B8Y828 R-XTR-8937050 https://reactome.org/PathwayBrowser/#/R-XTR-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Xenopus tropicalis A0A1B8Y828 R-XTR-8937113 https://reactome.org/PathwayBrowser/#/R-XTR-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Xenopus tropicalis A0A1B8Y828 R-XTR-9011949 https://reactome.org/PathwayBrowser/#/R-XTR-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Xenopus tropicalis A0A1B8Y828 R-XTR-9011952 https://reactome.org/PathwayBrowser/#/R-XTR-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Xenopus tropicalis A0A1B8Y828 R-XTR-9011981 https://reactome.org/PathwayBrowser/#/R-XTR-9011981 EP300 is recruited to MYC and BCL2 genes IEA Xenopus tropicalis A0A1B8Y828 R-XTR-9011983 https://reactome.org/PathwayBrowser/#/R-XTR-9011983 Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes IEA Xenopus tropicalis A0A1B8Y828 R-XTR-9011984 https://reactome.org/PathwayBrowser/#/R-XTR-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Xenopus tropicalis A0A1B8Y828 R-XTR-9011985 https://reactome.org/PathwayBrowser/#/R-XTR-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Xenopus tropicalis A0A1B8Y828 R-XTR-9012000 https://reactome.org/PathwayBrowser/#/R-XTR-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Xenopus tropicalis A0A1B8Y828 R-XTR-9629195 https://reactome.org/PathwayBrowser/#/R-XTR-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA IEA Xenopus tropicalis A0A1B8Y828 R-XTR-9629216 https://reactome.org/PathwayBrowser/#/R-XTR-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Xenopus tropicalis A0A1B8Y828 R-XTR-9749197 https://reactome.org/PathwayBrowser/#/R-XTR-9749197 ORC1 binds to H4K20me2 IEA Xenopus tropicalis A0A1B8Y828 R-XTR-9843118 https://reactome.org/PathwayBrowser/#/R-XTR-9843118 RXRA binds ligands IEA Xenopus tropicalis A0A1B8Y8P3 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis A0A1B8Y922 R-XTR-2396079 https://reactome.org/PathwayBrowser/#/R-XTR-2396079 VTN binds Plasminogen activator inhibitor- 1 IEA Xenopus tropicalis A0A1B8Y922 R-XTR-481007 https://reactome.org/PathwayBrowser/#/R-XTR-481007 Exocytosis of platelet alpha granule contents IEA Xenopus tropicalis A0A1B8Y9B0 R-XTR-5696534 https://reactome.org/PathwayBrowser/#/R-XTR-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Xenopus tropicalis A0A1B8Y9B0 R-XTR-912685 https://reactome.org/PathwayBrowser/#/R-XTR-912685 UBP43 binds IFNAR2 and prevents JAK1 interaction IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-1168640 https://reactome.org/PathwayBrowser/#/R-XTR-1168640 Ubiquitinated IkB is degraded IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-1234159 https://reactome.org/PathwayBrowser/#/R-XTR-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-1236970 https://reactome.org/PathwayBrowser/#/R-XTR-1236970 Proteasomal clevage of exogenous antigen (26S proteasome catalyst) IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-174058 https://reactome.org/PathwayBrowser/#/R-XTR-174058 Degradation of multiubiquitinated Cdh1 IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-174105 https://reactome.org/PathwayBrowser/#/R-XTR-174105 Degradation of multiubiquitinated cell cycle proteins IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-174202 https://reactome.org/PathwayBrowser/#/R-XTR-174202 Degradation of multiubiquitinated Securin IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-174203 https://reactome.org/PathwayBrowser/#/R-XTR-174203 SCF-mediated degradation of Emi1 IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-174255 https://reactome.org/PathwayBrowser/#/R-XTR-174255 Degradation multiubiquitinated Cyclin A IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-187574 https://reactome.org/PathwayBrowser/#/R-XTR-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-188191 https://reactome.org/PathwayBrowser/#/R-XTR-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-264458 https://reactome.org/PathwayBrowser/#/R-XTR-264458 Proteasome mediated degradation of COP1 IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-353125 https://reactome.org/PathwayBrowser/#/R-XTR-353125 26S proteosome degrades ODC holoenzyme complex IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-450466 https://reactome.org/PathwayBrowser/#/R-XTR-450466 AUF1:mRNA complex is destroyed IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-4608855 https://reactome.org/PathwayBrowser/#/R-XTR-4608855 PRICKLE1 is degraded by the proteasome IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-4641256 https://reactome.org/PathwayBrowser/#/R-XTR-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-5362448 https://reactome.org/PathwayBrowser/#/R-XTR-5362448 Hh C-terminal fragments are degraded by the proteasome IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-5610754 https://reactome.org/PathwayBrowser/#/R-XTR-5610754 GLI3 is partially degraded by the proteasome to yield the GLI3 repressor IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-5610758 https://reactome.org/PathwayBrowser/#/R-XTR-5610758 GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-5610760 https://reactome.org/PathwayBrowser/#/R-XTR-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-5635854 https://reactome.org/PathwayBrowser/#/R-XTR-5635854 GLI2,3 are degraded by the proteasome IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-5635868 https://reactome.org/PathwayBrowser/#/R-XTR-5635868 ub-GLI is degraded by the proteasome IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-5665854 https://reactome.org/PathwayBrowser/#/R-XTR-5665854 ADRM1:26S proteaseome binds UCHL5 IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-5665871 https://reactome.org/PathwayBrowser/#/R-XTR-5665871 ADRM1 binds 26S proteasome IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-5668481 https://reactome.org/PathwayBrowser/#/R-XTR-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-5668520 https://reactome.org/PathwayBrowser/#/R-XTR-5668520 26Sproteasome degrades K48polyUb-NIK IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-5687112 https://reactome.org/PathwayBrowser/#/R-XTR-5687112 MAPK6 is degraded by the 26S proteasome IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-5689539 https://reactome.org/PathwayBrowser/#/R-XTR-5689539 ADRM1:26S proteaseome binds USP14 IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-6798748 https://reactome.org/PathwayBrowser/#/R-XTR-6798748 Exocytosis of secretory granule lumen proteins IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-6800434 https://reactome.org/PathwayBrowser/#/R-XTR-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-68825 https://reactome.org/PathwayBrowser/#/R-XTR-68825 Ubiquitinated geminin is degraded by the proteasome IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-68948 https://reactome.org/PathwayBrowser/#/R-XTR-68948 Ubiquitinated Orc1 is degraded by the proteasome IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-69016 https://reactome.org/PathwayBrowser/#/R-XTR-69016 Ubiquitinated Cdc6 is degraded by the proteasome IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-69600 https://reactome.org/PathwayBrowser/#/R-XTR-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-75825 https://reactome.org/PathwayBrowser/#/R-XTR-75825 Proteasome mediated degradation of Cyclin D1 IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-8850992 https://reactome.org/PathwayBrowser/#/R-XTR-8850992 Proteasome degrades polyubiquitinated PTEN IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-8852354 https://reactome.org/PathwayBrowser/#/R-XTR-8852354 GTSE1 facilitates proteasome-mediated degradation of TP53 IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-8854044 https://reactome.org/PathwayBrowser/#/R-XTR-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-8866553 https://reactome.org/PathwayBrowser/#/R-XTR-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-8932355 https://reactome.org/PathwayBrowser/#/R-XTR-8932355 26S proteasome degrades Ub-NFE2L2 IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-8939801 https://reactome.org/PathwayBrowser/#/R-XTR-8939801 26S proteasome degrades PolyUb-RUNX2 IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-8956140 https://reactome.org/PathwayBrowser/#/R-XTR-8956140 NEDD8 and UBD bind NUB1 and the 26S proteasome IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-8956184 https://reactome.org/PathwayBrowser/#/R-XTR-8956184 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-8957265 https://reactome.org/PathwayBrowser/#/R-XTR-8957265 26S proteasome degrades TP73 polyubiquitinated by ITCH IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-9755303 https://reactome.org/PathwayBrowser/#/R-XTR-9755303 26S proteasome degrades HIFalpha IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-9762096 https://reactome.org/PathwayBrowser/#/R-XTR-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-983150 https://reactome.org/PathwayBrowser/#/R-XTR-983150 Proteasomal cleavage of substrate IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-9908019 https://reactome.org/PathwayBrowser/#/R-XTR-9908019 Formation of the 19S regulatory particle lid IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-9908026 https://reactome.org/PathwayBrowser/#/R-XTR-9908026 Formation of the 19S regulatory particle precursor IEA Xenopus tropicalis A0A1B8Y9B4 R-XTR-9934893 https://reactome.org/PathwayBrowser/#/R-XTR-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 IEA Xenopus tropicalis A0A1B8Y9C0 R-XTR-190682 https://reactome.org/PathwayBrowser/#/R-XTR-190682 Connexin synthesis (generic) IEA Xenopus tropicalis A0A1B8Y9F0 R-XTR-6805546 https://reactome.org/PathwayBrowser/#/R-XTR-6805546 Keratin type I binds keratin type II IEA Xenopus tropicalis A0A1B8Y9F0 R-XTR-6805573 https://reactome.org/PathwayBrowser/#/R-XTR-6805573 Keratin type I/type II heterodimers form tetramers IEA Xenopus tropicalis A0A1B8Y9F0 R-XTR-6806610 https://reactome.org/PathwayBrowser/#/R-XTR-6806610 Keratin filament formation IEA Xenopus tropicalis A0A1B8Y9F0 R-XTR-6806613 https://reactome.org/PathwayBrowser/#/R-XTR-6806613 Keratin tetramers bind to form unit length filaments IEA Xenopus tropicalis A0A1B8Y9F0 R-XTR-6806629 https://reactome.org/PathwayBrowser/#/R-XTR-6806629 Formation of tonofilament bundles IEA Xenopus tropicalis A0A1B8Y9F0 R-XTR-6809393 https://reactome.org/PathwayBrowser/#/R-XTR-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Xenopus tropicalis A0A1B8Y9F0 R-XTR-6810357 https://reactome.org/PathwayBrowser/#/R-XTR-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Xenopus tropicalis A0A1B8YAJ2 R-XTR-71775 https://reactome.org/PathwayBrowser/#/R-XTR-71775 SUCLG1/G2 cleaves succinyl-CoA IEA Xenopus tropicalis A0A1B8YAJ2 R-XTR-9838035 https://reactome.org/PathwayBrowser/#/R-XTR-9838035 CLPXP binds mitochondrial matrix proteins IEA Xenopus tropicalis A0A1B8YAJ2 R-XTR-9838289 https://reactome.org/PathwayBrowser/#/R-XTR-9838289 CLPXP degrades mitochondrial matrix proteins IEA Xenopus tropicalis A0A1C3NSK2 R-CEL-1013012 https://reactome.org/PathwayBrowser/#/R-CEL-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Caenorhabditis elegans A0A1C3NSK2 R-CEL-1013020 https://reactome.org/PathwayBrowser/#/R-CEL-1013020 Activation of GIRK/Kir3 Channels IEA Caenorhabditis elegans A0A1C3NSK2 R-CEL-1296045 https://reactome.org/PathwayBrowser/#/R-CEL-1296045 Activation of Potassium transport channels IEA Caenorhabditis elegans A0A1C3NSK2 R-CEL-1296046 https://reactome.org/PathwayBrowser/#/R-CEL-1296046 KCNJs transport K+ from the extracellular region to cytosol IEA Caenorhabditis elegans A0A1C3NSL8 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans A0A1C3NSL8 R-CEL-5693691 https://reactome.org/PathwayBrowser/#/R-CEL-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Caenorhabditis elegans A0A1C3NSL8 R-CEL-8937442 https://reactome.org/PathwayBrowser/#/R-CEL-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Caenorhabditis elegans A0A1C3NSL8 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans A0A1C3NSL8 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans A0A1C3NSL8 R-CEL-9727567 https://reactome.org/PathwayBrowser/#/R-CEL-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Caenorhabditis elegans A0A1C3NSL8 R-CEL-9749647 https://reactome.org/PathwayBrowser/#/R-CEL-9749647 CES2 hydrolyzes ASA- IEA Caenorhabditis elegans A0A1C3NSL8 R-CEL-9749792 https://reactome.org/PathwayBrowser/#/R-CEL-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Caenorhabditis elegans A0A1C3NSN6 R-CEL-1013012 https://reactome.org/PathwayBrowser/#/R-CEL-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Caenorhabditis elegans A0A1C3NSN6 R-CEL-1013020 https://reactome.org/PathwayBrowser/#/R-CEL-1013020 Activation of GIRK/Kir3 Channels IEA Caenorhabditis elegans A0A1C3NSN6 R-CEL-1296045 https://reactome.org/PathwayBrowser/#/R-CEL-1296045 Activation of Potassium transport channels IEA Caenorhabditis elegans A0A1C3NSN6 R-CEL-1296046 https://reactome.org/PathwayBrowser/#/R-CEL-1296046 KCNJs transport K+ from the extracellular region to cytosol IEA Caenorhabditis elegans A0A1C7CYU2 R-GGA-1855163 https://reactome.org/PathwayBrowser/#/R-GGA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Gallus gallus A0A1C7CYU2 R-GGA-1855200 https://reactome.org/PathwayBrowser/#/R-GGA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Gallus gallus A0A1C7CYU2 R-GGA-1855225 https://reactome.org/PathwayBrowser/#/R-GGA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Gallus gallus A0A1D5NSC9 R-DRE-71261 https://reactome.org/PathwayBrowser/#/R-DRE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Danio rerio A0A1D5NSQ4 R-DRE-374758 https://reactome.org/PathwayBrowser/#/R-DRE-374758 Somatostatin receptors bind somatostatin and cortistatin IEA Danio rerio A0A1D5NSQ4 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio A0A1D5NT34 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus A0A1D5NT34 R-GGA-9013022 https://reactome.org/PathwayBrowser/#/R-GGA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Gallus gallus A0A1D5NT34 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus A0A1D5NT61 R-GGA-5688276 https://reactome.org/PathwayBrowser/#/R-GGA-5688276 SIRT4 transfers ADPRib to GLUD IEA Gallus gallus A0A1D5NT61 R-GGA-5688289 https://reactome.org/PathwayBrowser/#/R-GGA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Gallus gallus A0A1D5NT61 R-GGA-70589 https://reactome.org/PathwayBrowser/#/R-GGA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Gallus gallus A0A1D5NT61 R-GGA-70600 https://reactome.org/PathwayBrowser/#/R-GGA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Gallus gallus A0A1D5NT61 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1D5NT61 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1D5NT69 R-GGA-1675836 https://reactome.org/PathwayBrowser/#/R-GGA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Gallus gallus A0A1D5NT69 R-GGA-1675988 https://reactome.org/PathwayBrowser/#/R-GGA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Gallus gallus A0A1D5NT69 R-GGA-1675994 https://reactome.org/PathwayBrowser/#/R-GGA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Gallus gallus A0A1D5NT69 R-GGA-1676177 https://reactome.org/PathwayBrowser/#/R-GGA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Gallus gallus A0A1D5NT69 R-GGA-1676203 https://reactome.org/PathwayBrowser/#/R-GGA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Gallus gallus A0A1D5NT69 R-GGA-1855174 https://reactome.org/PathwayBrowser/#/R-GGA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Gallus gallus A0A1D5NT69 R-GGA-1855218 https://reactome.org/PathwayBrowser/#/R-GGA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Gallus gallus A0A1D5NT69 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5NT69 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5NT69 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5NT69 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5NT69 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5NT69 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5NT69 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5NT72 R-GGA-189465 https://reactome.org/PathwayBrowser/#/R-GGA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Gallus gallus A0A1D5NT72 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1D5NT72 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1D5NT76 R-GGA-6798745 https://reactome.org/PathwayBrowser/#/R-GGA-6798745 Exocytosis of tertiary granule lumen proteins IEA Gallus gallus A0A1D5NT76 R-GGA-6798749 https://reactome.org/PathwayBrowser/#/R-GGA-6798749 Exocytosis of specific granule lumen proteins IEA Gallus gallus A0A1D5NT76 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5NT76 R-GGA-9836383 https://reactome.org/PathwayBrowser/#/R-GGA-9836383 p-PKR dimer phosphorylates ILF3:ILF2 IEA Gallus gallus A0A1D5NT86 R-GGA-5336453 https://reactome.org/PathwayBrowser/#/R-GGA-5336453 NIPAs transport Mg2+ from extracellular region to cytosol IEA Gallus gallus A0A1D5NT90 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus A0A1D5NT90 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus A0A1D5NT90 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus A0A1D5NT90 R-GGA-5694417 https://reactome.org/PathwayBrowser/#/R-GGA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Gallus gallus A0A1D5NT90 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus A0A1D5NT90 R-GGA-5694428 https://reactome.org/PathwayBrowser/#/R-GGA-5694428 LMAN family proteins bind glycosylated cargo IEA Gallus gallus A0A1D5NT90 R-GGA-5694431 https://reactome.org/PathwayBrowser/#/R-GGA-5694431 Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors IEA Gallus gallus A0A1D5NT90 R-GGA-5694446 https://reactome.org/PathwayBrowser/#/R-GGA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Gallus gallus A0A1D5NT90 R-GGA-5694522 https://reactome.org/PathwayBrowser/#/R-GGA-5694522 Inner coat assembly and cargo binding IEA Gallus gallus A0A1D5NT90 R-GGA-5694527 https://reactome.org/PathwayBrowser/#/R-GGA-5694527 Loss of SAR1B GTPase IEA Gallus gallus A0A1D5NT90 R-GGA-9013004 https://reactome.org/PathwayBrowser/#/R-GGA-9013004 RHOA binds effectors at the ER membrane IEA Gallus gallus A0A1D5NT90 R-GGA-9014467 https://reactome.org/PathwayBrowser/#/R-GGA-9014467 RHOG binds effectors at the ER membrane IEA Gallus gallus A0A1D5NT90 R-GGA-9693250 https://reactome.org/PathwayBrowser/#/R-GGA-9693250 RHOD binds effectors at the Golgi membrane IEA Gallus gallus A0A1D5NT90 R-GGA-9714361 https://reactome.org/PathwayBrowser/#/R-GGA-9714361 RHOC activates endoplasmic reticulum effectors IEA Gallus gallus A0A1D5NTA2 R-GGA-5667008 https://reactome.org/PathwayBrowser/#/R-GGA-5667008 RHOA:GTP binds RHPN1 or RHPN2 IEA Gallus gallus A0A1D5NTA2 R-GGA-9013009 https://reactome.org/PathwayBrowser/#/R-GGA-9013009 RHOA binds effectors at the plasma membrane IEA Gallus gallus A0A1D5NTC7 R-GGA-4084984 https://reactome.org/PathwayBrowser/#/R-GGA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Gallus gallus A0A1D5NTC7 R-GGA-9844860 https://reactome.org/PathwayBrowser/#/R-GGA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Gallus gallus A0A1D5NTC8 R-GGA-182986 https://reactome.org/PathwayBrowser/#/R-GGA-182986 CBL-mediated ubiquitination of CIN85 IEA Gallus gallus A0A1D5NTC8 R-GGA-182990 https://reactome.org/PathwayBrowser/#/R-GGA-182990 Sprouty sequesters CBL away from active EGFR IEA Gallus gallus A0A1D5NTC8 R-GGA-5693061 https://reactome.org/PathwayBrowser/#/R-GGA-5693061 STAMBP binds STAM IEA Gallus gallus A0A1D5NTC8 R-GGA-5696547 https://reactome.org/PathwayBrowser/#/R-GGA-5696547 STAMBPL1 is a deubiquitinase IEA Gallus gallus A0A1D5NTC8 R-GGA-8866279 https://reactome.org/PathwayBrowser/#/R-GGA-8866279 Epsin family proteins bind ubiquitinated cargo IEA Gallus gallus A0A1D5NTC8 R-GGA-8867041 https://reactome.org/PathwayBrowser/#/R-GGA-8867041 EGFR phosphorylates EPS15 IEA Gallus gallus A0A1D5NTC8 R-GGA-8867047 https://reactome.org/PathwayBrowser/#/R-GGA-8867047 PTPN3 dephosphorylates EPS15 IEA Gallus gallus A0A1D5NTC8 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5NTC8 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5NTC8 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5NTC8 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5NTC8 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5NTC8 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5NTC8 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5NTC8 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5NTC8 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5NTC8 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5NTC8 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5NTC8 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5NTC8 R-GGA-8875490 https://reactome.org/PathwayBrowser/#/R-GGA-8875490 EPS15 and HGS bind ubiquitinated MET IEA Gallus gallus A0A1D5NTC8 R-GGA-9018766 https://reactome.org/PathwayBrowser/#/R-GGA-9018766 RHOU binds effectors at the plasma membrane IEA Gallus gallus A0A1D5NTC8 R-GGA-917730 https://reactome.org/PathwayBrowser/#/R-GGA-917730 Cargo Recognition And Sorting IEA Gallus gallus A0A1D5NTD3 R-GGA-1168640 https://reactome.org/PathwayBrowser/#/R-GGA-1168640 Ubiquitinated IkB is degraded IEA Gallus gallus A0A1D5NTD3 R-GGA-1234159 https://reactome.org/PathwayBrowser/#/R-GGA-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Gallus gallus A0A1D5NTD3 R-GGA-1236970 https://reactome.org/PathwayBrowser/#/R-GGA-1236970 Proteasomal clevage of exogenous antigen (26S proteasome catalyst) IEA Gallus gallus A0A1D5NTD3 R-GGA-1504193 https://reactome.org/PathwayBrowser/#/R-GGA-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-174058 https://reactome.org/PathwayBrowser/#/R-GGA-174058 Degradation of multiubiquitinated Cdh1 IEA Gallus gallus A0A1D5NTD3 R-GGA-174105 https://reactome.org/PathwayBrowser/#/R-GGA-174105 Degradation of multiubiquitinated cell cycle proteins IEA Gallus gallus A0A1D5NTD3 R-GGA-174202 https://reactome.org/PathwayBrowser/#/R-GGA-174202 Degradation of multiubiquitinated Securin IEA Gallus gallus A0A1D5NTD3 R-GGA-174255 https://reactome.org/PathwayBrowser/#/R-GGA-174255 Degradation multiubiquitinated Cyclin A IEA Gallus gallus A0A1D5NTD3 R-GGA-187574 https://reactome.org/PathwayBrowser/#/R-GGA-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-188191 https://reactome.org/PathwayBrowser/#/R-GGA-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Gallus gallus A0A1D5NTD3 R-GGA-209061 https://reactome.org/PathwayBrowser/#/R-GGA-209061 Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex IEA Gallus gallus A0A1D5NTD3 R-GGA-2130282 https://reactome.org/PathwayBrowser/#/R-GGA-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-264458 https://reactome.org/PathwayBrowser/#/R-GGA-264458 Proteasome mediated degradation of COP1 IEA Gallus gallus A0A1D5NTD3 R-GGA-353125 https://reactome.org/PathwayBrowser/#/R-GGA-353125 26S proteosome degrades ODC holoenzyme complex IEA Gallus gallus A0A1D5NTD3 R-GGA-3640874 https://reactome.org/PathwayBrowser/#/R-GGA-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-450466 https://reactome.org/PathwayBrowser/#/R-GGA-450466 AUF1:mRNA complex is destroyed IEA Gallus gallus A0A1D5NTD3 R-GGA-4608855 https://reactome.org/PathwayBrowser/#/R-GGA-4608855 PRICKLE1 is degraded by the proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-4641256 https://reactome.org/PathwayBrowser/#/R-GGA-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-5362448 https://reactome.org/PathwayBrowser/#/R-GGA-5362448 Hh C-terminal fragments are degraded by the proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-5607724 https://reactome.org/PathwayBrowser/#/R-GGA-5607724 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex IEA Gallus gallus A0A1D5NTD3 R-GGA-5610754 https://reactome.org/PathwayBrowser/#/R-GGA-5610754 GLI3 is partially degraded by the proteasome to yield the GLI3 repressor IEA Gallus gallus A0A1D5NTD3 R-GGA-5610758 https://reactome.org/PathwayBrowser/#/R-GGA-5610758 GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP IEA Gallus gallus A0A1D5NTD3 R-GGA-5610760 https://reactome.org/PathwayBrowser/#/R-GGA-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Gallus gallus A0A1D5NTD3 R-GGA-5635854 https://reactome.org/PathwayBrowser/#/R-GGA-5635854 GLI2,3 are degraded by the proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-5635868 https://reactome.org/PathwayBrowser/#/R-GGA-5635868 ub-GLI is degraded by the proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-5658430 https://reactome.org/PathwayBrowser/#/R-GGA-5658430 NF1 is degraded by the proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-5665854 https://reactome.org/PathwayBrowser/#/R-GGA-5665854 ADRM1:26S proteaseome binds UCHL5 IEA Gallus gallus A0A1D5NTD3 R-GGA-5665871 https://reactome.org/PathwayBrowser/#/R-GGA-5665871 ADRM1 binds 26S proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-5668481 https://reactome.org/PathwayBrowser/#/R-GGA-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Gallus gallus A0A1D5NTD3 R-GGA-5668520 https://reactome.org/PathwayBrowser/#/R-GGA-5668520 26Sproteasome degrades K48polyUb-NIK IEA Gallus gallus A0A1D5NTD3 R-GGA-5687112 https://reactome.org/PathwayBrowser/#/R-GGA-5687112 MAPK6 is degraded by the 26S proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-5689539 https://reactome.org/PathwayBrowser/#/R-GGA-5689539 ADRM1:26S proteaseome binds USP14 IEA Gallus gallus A0A1D5NTD3 R-GGA-68825 https://reactome.org/PathwayBrowser/#/R-GGA-68825 Ubiquitinated geminin is degraded by the proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-68948 https://reactome.org/PathwayBrowser/#/R-GGA-68948 Ubiquitinated Orc1 is degraded by the proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-69016 https://reactome.org/PathwayBrowser/#/R-GGA-69016 Ubiquitinated Cdc6 is degraded by the proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-69600 https://reactome.org/PathwayBrowser/#/R-GGA-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Gallus gallus A0A1D5NTD3 R-GGA-75825 https://reactome.org/PathwayBrowser/#/R-GGA-75825 Proteasome mediated degradation of Cyclin D1 IEA Gallus gallus A0A1D5NTD3 R-GGA-8850992 https://reactome.org/PathwayBrowser/#/R-GGA-8850992 Proteasome degrades polyubiquitinated PTEN IEA Gallus gallus A0A1D5NTD3 R-GGA-8854044 https://reactome.org/PathwayBrowser/#/R-GGA-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Gallus gallus A0A1D5NTD3 R-GGA-8854071 https://reactome.org/PathwayBrowser/#/R-GGA-8854071 Proteasome-mediated degradation of PolyUb-FBXL7 IEA Gallus gallus A0A1D5NTD3 R-GGA-8866553 https://reactome.org/PathwayBrowser/#/R-GGA-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-8932355 https://reactome.org/PathwayBrowser/#/R-GGA-8932355 26S proteasome degrades Ub-NFE2L2 IEA Gallus gallus A0A1D5NTD3 R-GGA-8939801 https://reactome.org/PathwayBrowser/#/R-GGA-8939801 26S proteasome degrades PolyUb-RUNX2 IEA Gallus gallus A0A1D5NTD3 R-GGA-8952408 https://reactome.org/PathwayBrowser/#/R-GGA-8952408 Polyubiquitinated RUNX3 is degraded by the proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-8956140 https://reactome.org/PathwayBrowser/#/R-GGA-8956140 NEDD8 and UBD bind NUB1 and the 26S proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-8956184 https://reactome.org/PathwayBrowser/#/R-GGA-8956184 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates IEA Gallus gallus A0A1D5NTD3 R-GGA-8957265 https://reactome.org/PathwayBrowser/#/R-GGA-8957265 26S proteasome degrades TP73 polyubiquitinated by ITCH IEA Gallus gallus A0A1D5NTD3 R-GGA-9755303 https://reactome.org/PathwayBrowser/#/R-GGA-9755303 26S proteasome degrades HIFalpha IEA Gallus gallus A0A1D5NTD3 R-GGA-9755306 https://reactome.org/PathwayBrowser/#/R-GGA-9755306 ub UBXN7 is degraded by the 26S proteasome IEA Gallus gallus A0A1D5NTD3 R-GGA-9762096 https://reactome.org/PathwayBrowser/#/R-GGA-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Gallus gallus A0A1D5NTD3 R-GGA-983150 https://reactome.org/PathwayBrowser/#/R-GGA-983150 Proteasomal cleavage of substrate IEA Gallus gallus A0A1D5NTD3 R-GGA-9908026 https://reactome.org/PathwayBrowser/#/R-GGA-9908026 Formation of the 19S regulatory particle precursor IEA Gallus gallus A0A1D5NTD3 R-GGA-9934893 https://reactome.org/PathwayBrowser/#/R-GGA-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 IEA Gallus gallus A0A1D5NTD4 R-GGA-6785342 https://reactome.org/PathwayBrowser/#/R-GGA-6785342 FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex IEA Gallus gallus A0A1D5NTD4 R-GGA-6785361 https://reactome.org/PathwayBrowser/#/R-GGA-6785361 Monoubiquitination of FANCD2:FANCI IEA Gallus gallus A0A1D5NTD4 R-GGA-6788385 https://reactome.org/PathwayBrowser/#/R-GGA-6788385 The complex of ATR and ATRIP is recruited to ICL-DNA IEA Gallus gallus A0A1D5NTD4 R-GGA-6788392 https://reactome.org/PathwayBrowser/#/R-GGA-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Gallus gallus A0A1D5NTD4 R-GGA-8852130 https://reactome.org/PathwayBrowser/#/R-GGA-8852130 UBA1 conjugates ubiquitin to nuclear E2 enzymes IEA Gallus gallus A0A1D5NTE0 R-GGA-9693125 https://reactome.org/PathwayBrowser/#/R-GGA-9693125 RHOF binds effectors at the plasma membrane IEA Gallus gallus A0A1D5NTE0 R-GGA-9693198 https://reactome.org/PathwayBrowser/#/R-GGA-9693198 RHOD binds effectors at the plasma membrane IEA Gallus gallus A0A1D5NTF4 R-GGA-3247837 https://reactome.org/PathwayBrowser/#/R-GGA-3247837 WNT ligands traffic to the Golgi IEA Gallus gallus A0A1D5NTF4 R-GGA-3247840 https://reactome.org/PathwayBrowser/#/R-GGA-3247840 WLS binds WNT ligands in the Golgi IEA Gallus gallus A0A1D5NTF4 R-GGA-3247843 https://reactome.org/PathwayBrowser/#/R-GGA-3247843 secretion of WNT ligands IEA Gallus gallus A0A1D5NTF4 R-GGA-3247844 https://reactome.org/PathwayBrowser/#/R-GGA-3247844 WNT ligands traffic to the plasma membrane IEA Gallus gallus A0A1D5NTF4 R-GGA-3781941 https://reactome.org/PathwayBrowser/#/R-GGA-3781941 WNTs are secreted in exosomes IEA Gallus gallus A0A1D5NTF4 R-GGA-3781943 https://reactome.org/PathwayBrowser/#/R-GGA-3781943 WLS:WNT complex is internalized for maturation into exosomes IEA Gallus gallus A0A1D5NTG0 R-GGA-5691006 https://reactome.org/PathwayBrowser/#/R-GGA-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Gallus gallus A0A1D5NTG0 R-GGA-6781833 https://reactome.org/PathwayBrowser/#/R-GGA-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Gallus gallus A0A1D5NTG0 R-GGA-8863721 https://reactome.org/PathwayBrowser/#/R-GGA-8863721 NEDD8-STON binds TOR1 hexamer and COP9 complex IEA Gallus gallus A0A1D5NTG0 R-GGA-8863723 https://reactome.org/PathwayBrowser/#/R-GGA-8863723 COP9 and TOR1 deneddylate STON2 IEA Gallus gallus A0A1D5NTG0 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5NTG0 R-GGA-8956045 https://reactome.org/PathwayBrowser/#/R-GGA-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NTG1 R-GGA-8953917 https://reactome.org/PathwayBrowser/#/R-GGA-8953917 PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 IEA Gallus gallus A0A1D5NTG1 R-GGA-8953946 https://reactome.org/PathwayBrowser/#/R-GGA-8953946 PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 IEA Gallus gallus A0A1D5NTG1 R-GGA-9033235 https://reactome.org/PathwayBrowser/#/R-GGA-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1D5NTG1 R-GGA-9033236 https://reactome.org/PathwayBrowser/#/R-GGA-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Gallus gallus A0A1D5NTG1 R-GGA-9033485 https://reactome.org/PathwayBrowser/#/R-GGA-9033485 PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 IEA Gallus gallus A0A1D5NTG1 R-GGA-9033491 https://reactome.org/PathwayBrowser/#/R-GGA-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Gallus gallus A0A1D5NTG1 R-GGA-9033499 https://reactome.org/PathwayBrowser/#/R-GGA-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Gallus gallus A0A1D5NTG1 R-GGA-9033509 https://reactome.org/PathwayBrowser/#/R-GGA-9033509 USP9X binds Ub:PEX5L IEA Gallus gallus A0A1D5NTG1 R-GGA-9033514 https://reactome.org/PathwayBrowser/#/R-GGA-9033514 Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1D5NTG1 R-GGA-9033516 https://reactome.org/PathwayBrowser/#/R-GGA-9033516 PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Gallus gallus A0A1D5NTG1 R-GGA-9033527 https://reactome.org/PathwayBrowser/#/R-GGA-9033527 PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 IEA Gallus gallus A0A1D5NTG1 R-GGA-9033533 https://reactome.org/PathwayBrowser/#/R-GGA-9033533 PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Gallus gallus A0A1D5NTG1 R-GGA-9664850 https://reactome.org/PathwayBrowser/#/R-GGA-9664850 ATM binds PEX5 IEA Gallus gallus A0A1D5NTG1 R-GGA-9664855 https://reactome.org/PathwayBrowser/#/R-GGA-9664855 MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 IEA Gallus gallus A0A1D5NTG1 R-GGA-9664862 https://reactome.org/PathwayBrowser/#/R-GGA-9664862 ATM dimer:PEX5 phosphorylates PEX5 IEA Gallus gallus A0A1D5NTG1 R-GGA-9664879 https://reactome.org/PathwayBrowser/#/R-GGA-9664879 ATM:PEX5 binds ATM IEA Gallus gallus A0A1D5NTG1 R-GGA-9664880 https://reactome.org/PathwayBrowser/#/R-GGA-9664880 MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 IEA Gallus gallus A0A1D5NTG1 R-GGA-9664881 https://reactome.org/PathwayBrowser/#/R-GGA-9664881 NBR1 binds ATM:Ub-p-PEX5:SQSTM1 IEA Gallus gallus A0A1D5NTG1 R-GGA-9664883 https://reactome.org/PathwayBrowser/#/R-GGA-9664883 ATM:PEX5 translocates from cytosol to peroxisomal membrane IEA Gallus gallus A0A1D5NTG1 R-GGA-9664888 https://reactome.org/PathwayBrowser/#/R-GGA-9664888 ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 IEA Gallus gallus A0A1D5NTG1 R-GGA-9664892 https://reactome.org/PathwayBrowser/#/R-GGA-9664892 SQSTM1 binds ATM dimer:Ub-p-PEX5 IEA Gallus gallus A0A1D5NTG1 R-GGA-9674127 https://reactome.org/PathwayBrowser/#/R-GGA-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Gallus gallus A0A1D5NTG1 R-GGA-9674131 https://reactome.org/PathwayBrowser/#/R-GGA-9674131 USP30 binds ATM dimer:Ub-p-PEX5 IEA Gallus gallus A0A1D5NTG9 R-GGA-2076611 https://reactome.org/PathwayBrowser/#/R-GGA-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Gallus gallus A0A1D5NTH5 R-GGA-9018787 https://reactome.org/PathwayBrowser/#/R-GGA-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Gallus gallus A0A1D5NTH6 R-GGA-1667005 https://reactome.org/PathwayBrowser/#/R-GGA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Gallus gallus A0A1D5NTH6 R-GGA-1678694 https://reactome.org/PathwayBrowser/#/R-GGA-1678694 Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans IEA Gallus gallus A0A1D5NTH6 R-GGA-1878002 https://reactome.org/PathwayBrowser/#/R-GGA-1878002 XYLTs transfer Xyl to core protein IEA Gallus gallus A0A1D5NTH6 R-GGA-1889955 https://reactome.org/PathwayBrowser/#/R-GGA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Gallus gallus A0A1D5NTH6 R-GGA-1889981 https://reactome.org/PathwayBrowser/#/R-GGA-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Gallus gallus A0A1D5NTH6 R-GGA-2022860 https://reactome.org/PathwayBrowser/#/R-GGA-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Gallus gallus A0A1D5NTH6 R-GGA-2022887 https://reactome.org/PathwayBrowser/#/R-GGA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Gallus gallus A0A1D5NTH6 R-GGA-2024084 https://reactome.org/PathwayBrowser/#/R-GGA-2024084 HS-GAGs translocate to the lysosome for degradation IEA Gallus gallus A0A1D5NTH6 R-GGA-2024108 https://reactome.org/PathwayBrowser/#/R-GGA-2024108 Some HSPGs are secreted to the plasma membrane IEA Gallus gallus A0A1D5NTH6 R-GGA-2076383 https://reactome.org/PathwayBrowser/#/R-GGA-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Gallus gallus A0A1D5NTH6 R-GGA-2076419 https://reactome.org/PathwayBrowser/#/R-GGA-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Gallus gallus A0A1D5NTH6 R-GGA-2076508 https://reactome.org/PathwayBrowser/#/R-GGA-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Gallus gallus A0A1D5NTH6 R-GGA-2076611 https://reactome.org/PathwayBrowser/#/R-GGA-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Gallus gallus A0A1D5NTH6 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5NTH7 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5NTJ0 R-GGA-3965444 https://reactome.org/PathwayBrowser/#/R-GGA-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Gallus gallus A0A1D5NTJ0 R-GGA-3965447 https://reactome.org/PathwayBrowser/#/R-GGA-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Gallus gallus A0A1D5NTJ5 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5NTJ5 R-GGA-6799350 https://reactome.org/PathwayBrowser/#/R-GGA-6799350 Exocytosis of specific granule membrane proteins IEA Gallus gallus A0A1D5NTK5 R-GGA-8933328 https://reactome.org/PathwayBrowser/#/R-GGA-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Gallus gallus A0A1D5NTQ2 R-GGA-204813 https://reactome.org/PathwayBrowser/#/R-GGA-204813 Interaction of Tie2 and Grb14 IEA Gallus gallus A0A1D5NTR2 R-GGA-212222 https://reactome.org/PathwayBrowser/#/R-GGA-212222 PRC2 recruits DNA methyltransferases IEA Gallus gallus A0A1D5NTR2 R-GGA-212269 https://reactome.org/PathwayBrowser/#/R-GGA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Gallus gallus A0A1D5NTR2 R-GGA-5212679 https://reactome.org/PathwayBrowser/#/R-GGA-5212679 DNMT3A binds Me2sR4-HIST1H4 IEA Gallus gallus A0A1D5NTR8 R-GGA-8952618 https://reactome.org/PathwayBrowser/#/R-GGA-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NTR8 R-GGA-8952620 https://reactome.org/PathwayBrowser/#/R-GGA-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NTR8 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5NTR8 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5NTR8 R-GGA-8956200 https://reactome.org/PathwayBrowser/#/R-GGA-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NTR8 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5NTR8 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5NTR8 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5NTR8 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5NTR9 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5NTS9 R-GGA-6814094 https://reactome.org/PathwayBrowser/#/R-GGA-6814094 ARL1:GTP binds ARFIP2 IEA Gallus gallus A0A1D5NTT2 R-GGA-6806831 https://reactome.org/PathwayBrowser/#/R-GGA-6806831 CYB5Rs reduce MetHb to HbA IEA Gallus gallus A0A1D5NTT4 R-GGA-5205649 https://reactome.org/PathwayBrowser/#/R-GGA-5205649 p62 links damaged mitochondria to LC3 IEA Gallus gallus A0A1D5NTT4 R-GGA-5205663 https://reactome.org/PathwayBrowser/#/R-GGA-5205663 LC3 binds the autophagosome membrane Atg5-Atg12 complex IEA Gallus gallus A0A1D5NTT4 R-GGA-5205673 https://reactome.org/PathwayBrowser/#/R-GGA-5205673 p62 binds ubiquitinated mitochondrial substrates IEA Gallus gallus A0A1D5NTT4 R-GGA-5696872 https://reactome.org/PathwayBrowser/#/R-GGA-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Gallus gallus A0A1D5NTT4 R-GGA-9012374 https://reactome.org/PathwayBrowser/#/R-GGA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Gallus gallus A0A1D5NTT4 R-GGA-9824888 https://reactome.org/PathwayBrowser/#/R-GGA-9824888 OPTN, TBK1 bind ubiquitinated MOM proteins IEA Gallus gallus A0A1D5NTT4 R-GGA-9824892 https://reactome.org/PathwayBrowser/#/R-GGA-9824892 MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria IEA Gallus gallus A0A1D5NTT4 R-GGA-9824894 https://reactome.org/PathwayBrowser/#/R-GGA-9824894 TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins IEA Gallus gallus A0A1D5NTT4 R-GGA-9824897 https://reactome.org/PathwayBrowser/#/R-GGA-9824897 p-S-TBK1 phosphorylates OPTN IEA Gallus gallus A0A1D5NTT4 R-GGA-9835009 https://reactome.org/PathwayBrowser/#/R-GGA-9835009 PRKN binds p-S-Ub:MOM proteins IEA Gallus gallus A0A1D5NTT4 R-GGA-9840807 https://reactome.org/PathwayBrowser/#/R-GGA-9840807 OPTN binds ATG9A IEA Gallus gallus A0A1D5NTU6 R-GGA-2106614 https://reactome.org/PathwayBrowser/#/R-GGA-2106614 Duplex miRNA is loaded into Argonaute IEA Gallus gallus A0A1D5NTU6 R-GGA-2106615 https://reactome.org/PathwayBrowser/#/R-GGA-2106615 Removal of siRNA passenger strand IEA Gallus gallus A0A1D5NTU6 R-GGA-2106625 https://reactome.org/PathwayBrowser/#/R-GGA-2106625 Duplex siRNA is loaded into Argonaute IEA Gallus gallus A0A1D5NTU6 R-GGA-210805 https://reactome.org/PathwayBrowser/#/R-GGA-210805 Removal of miRNA passenger strand IEA Gallus gallus A0A1D5NTU6 R-GGA-426464 https://reactome.org/PathwayBrowser/#/R-GGA-426464 Dicer cleaves double-stranded RNA to yield double-stranded siRNA IEA Gallus gallus A0A1D5NTU6 R-GGA-426489 https://reactome.org/PathwayBrowser/#/R-GGA-426489 RISC binds inexactly matching target RNAs IEA Gallus gallus A0A1D5NTU6 R-GGA-426520 https://reactome.org/PathwayBrowser/#/R-GGA-426520 Endonucleolytic RISC hydrolyzes target RNAs IEA Gallus gallus A0A1D5NTU6 R-GGA-5578712 https://reactome.org/PathwayBrowser/#/R-GGA-5578712 Importin-8 binds AGO2:miRNA IEA Gallus gallus A0A1D5NTU6 R-GGA-5578742 https://reactome.org/PathwayBrowser/#/R-GGA-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Gallus gallus A0A1D5NTU6 R-GGA-5578744 https://reactome.org/PathwayBrowser/#/R-GGA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Gallus gallus A0A1D5NTU6 R-GGA-5578965 https://reactome.org/PathwayBrowser/#/R-GGA-5578965 TNRC6A binds AGO2:miRNA IEA Gallus gallus A0A1D5NTU6 R-GGA-5578966 https://reactome.org/PathwayBrowser/#/R-GGA-5578966 TNRC6A:AGO2:miRNA is transported into the nucleus IEA Gallus gallus A0A1D5NTU6 R-GGA-9023909 https://reactome.org/PathwayBrowser/#/R-GGA-9023909 C3PO hydrolyzes cleaved passenger strand IEA Gallus gallus A0A1D5NTU6 R-GGA-9023912 https://reactome.org/PathwayBrowser/#/R-GGA-9023912 AGO2 cleaves passenger strand of duplex siRNA IEA Gallus gallus A0A1D5NTV3 R-GGA-200555 https://reactome.org/PathwayBrowser/#/R-GGA-200555 Formation of Malonyl-CoA from Acetyl-CoA (liver) IEA Gallus gallus A0A1D5NTV3 R-GGA-2993814 https://reactome.org/PathwayBrowser/#/R-GGA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Gallus gallus A0A1D5NTV3 R-GGA-75851 https://reactome.org/PathwayBrowser/#/R-GGA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Gallus gallus A0A1D5NTX4 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5NTX4 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5NTX4 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5NTX4 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5NTX4 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5NTY7 R-GGA-2025723 https://reactome.org/PathwayBrowser/#/R-GGA-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Gallus gallus A0A1D5NTY7 R-GGA-2025724 https://reactome.org/PathwayBrowser/#/R-GGA-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG IEA Gallus gallus A0A1D5NTY7 R-GGA-2046175 https://reactome.org/PathwayBrowser/#/R-GGA-2046175 Further sulfation on galactose residues produces KSPG IEA Gallus gallus A0A1D5NTY7 R-GGA-2046180 https://reactome.org/PathwayBrowser/#/R-GGA-2046180 KSPG is secreted from the cell IEA Gallus gallus A0A1D5NTY7 R-GGA-2046222 https://reactome.org/PathwayBrowser/#/R-GGA-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Gallus gallus A0A1D5NTY7 R-GGA-2046239 https://reactome.org/PathwayBrowser/#/R-GGA-2046239 Extracellular KSPG translocates to the lysosome for degradation IEA Gallus gallus A0A1D5NTY7 R-GGA-2046265 https://reactome.org/PathwayBrowser/#/R-GGA-2046265 B4GALTs transfer Gal to the keratan chain IEA Gallus gallus A0A1D5NTY7 R-GGA-2046285 https://reactome.org/PathwayBrowser/#/R-GGA-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Gallus gallus A0A1D5NTY7 R-GGA-2046298 https://reactome.org/PathwayBrowser/#/R-GGA-2046298 B4GALTs transfer Gal to a branch of keratan IEA Gallus gallus A0A1D5NTZ7 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5NTZ7 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5NTZ7 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5NTZ7 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5NTZ7 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5NU01 R-GGA-381026 https://reactome.org/PathwayBrowser/#/R-GGA-381026 ATF6 (ATF6-alpha) translocates from the cytosol to the nucleus IEA Gallus gallus A0A1D5NU01 R-GGA-381135 https://reactome.org/PathwayBrowser/#/R-GGA-381135 MBTPS1 (S1P) cleaves ATF6 (ATF6-alpha) IEA Gallus gallus A0A1D5NU01 R-GGA-381186 https://reactome.org/PathwayBrowser/#/R-GGA-381186 ATF6 (ATF6-alpha) translocates from the endoplasmic reticulum to the Golgi IEA Gallus gallus A0A1D5NU01 R-GGA-420818 https://reactome.org/PathwayBrowser/#/R-GGA-420818 MBTPS2 (S2P) cleaves ATF6 (ATF6-alpha) IEA Gallus gallus A0A1D5NU01 R-GGA-9921802 https://reactome.org/PathwayBrowser/#/R-GGA-9921802 IFI6 binds HSPA5 IEA Gallus gallus A0A1D5NU03 R-GGA-2046285 https://reactome.org/PathwayBrowser/#/R-GGA-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Gallus gallus A0A1D5NU03 R-GGA-4084984 https://reactome.org/PathwayBrowser/#/R-GGA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Gallus gallus A0A1D5NU03 R-GGA-9603987 https://reactome.org/PathwayBrowser/#/R-GGA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Gallus gallus A0A1D5NU03 R-GGA-9605600 https://reactome.org/PathwayBrowser/#/R-GGA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Gallus gallus A0A1D5NU03 R-GGA-981497 https://reactome.org/PathwayBrowser/#/R-GGA-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Gallus gallus A0A1D5NU03 R-GGA-9845538 https://reactome.org/PathwayBrowser/#/R-GGA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Gallus gallus A0A1D5NU12 R-GGA-5610735 https://reactome.org/PathwayBrowser/#/R-GGA-5610735 NUMB binds ITCH IEA Gallus gallus A0A1D5NU12 R-GGA-5610737 https://reactome.org/PathwayBrowser/#/R-GGA-5610737 NUMB:ITCH bind and ubiquitnate GLI1 IEA Gallus gallus A0A1D5NU12 R-GGA-5610760 https://reactome.org/PathwayBrowser/#/R-GGA-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Gallus gallus A0A1D5NU12 R-GGA-5635861 https://reactome.org/PathwayBrowser/#/R-GGA-5635861 NUMB:ITCH binds GLI1 IEA Gallus gallus A0A1D5NU12 R-GGA-5635864 https://reactome.org/PathwayBrowser/#/R-GGA-5635864 NUMB:ITCH ubiquitinates GLI1 IEA Gallus gallus A0A1D5NU12 R-GGA-5635868 https://reactome.org/PathwayBrowser/#/R-GGA-5635868 ub-GLI is degraded by the proteasome IEA Gallus gallus A0A1D5NU19 R-GGA-9018758 https://reactome.org/PathwayBrowser/#/R-GGA-9018758 RHOH binds effectors at the plasma membrane IEA Gallus gallus A0A1D5NU23 R-GGA-5652005 https://reactome.org/PathwayBrowser/#/R-GGA-5652005 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA IEA Gallus gallus A0A1D5NU23 R-GGA-5652009 https://reactome.org/PathwayBrowser/#/R-GGA-5652009 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA IEA Gallus gallus A0A1D5NU23 R-GGA-8852130 https://reactome.org/PathwayBrowser/#/R-GGA-8852130 UBA1 conjugates ubiquitin to nuclear E2 enzymes IEA Gallus gallus A0A1D5NU23 R-GGA-8943003 https://reactome.org/PathwayBrowser/#/R-GGA-8943003 SHPRH polyubiquitinates monoubiquitinated PCNA IEA Gallus gallus A0A1D5NU23 R-GGA-8943007 https://reactome.org/PathwayBrowser/#/R-GGA-8943007 SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N IEA Gallus gallus A0A1D5NU23 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5NU23 R-GGA-983152 https://reactome.org/PathwayBrowser/#/R-GGA-983152 Transfer of ubiquitin from E1 to E2 IEA Gallus gallus A0A1D5NU23 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5NU23 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5NU40 R-GGA-8952618 https://reactome.org/PathwayBrowser/#/R-GGA-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NU40 R-GGA-8952620 https://reactome.org/PathwayBrowser/#/R-GGA-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NU40 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5NU40 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5NU40 R-GGA-8956200 https://reactome.org/PathwayBrowser/#/R-GGA-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NU40 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5NU40 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5NU40 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5NU40 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5NU66 R-GGA-1524182 https://reactome.org/PathwayBrowser/#/R-GGA-1524182 Activated PLC gamma dissociates from the PDGF receptor IEA Gallus gallus A0A1D5NU66 R-GGA-1524186 https://reactome.org/PathwayBrowser/#/R-GGA-1524186 Phosphorylation of PLCgamma by PDGFR IEA Gallus gallus A0A1D5NU66 R-GGA-186765 https://reactome.org/PathwayBrowser/#/R-GGA-186765 PLC-gamma binds to the active receptor IEA Gallus gallus A0A1D5NU66 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus A0A1D5NU66 R-GGA-186778 https://reactome.org/PathwayBrowser/#/R-GGA-186778 SHP2 binds to the active receptor IEA Gallus gallus A0A1D5NU66 R-GGA-186780 https://reactome.org/PathwayBrowser/#/R-GGA-186780 PI3-kinase binds to the active receptor IEA Gallus gallus A0A1D5NU66 R-GGA-186786 https://reactome.org/PathwayBrowser/#/R-GGA-186786 Autophosphorylation of PDGF beta receptors IEA Gallus gallus A0A1D5NU66 R-GGA-186798 https://reactome.org/PathwayBrowser/#/R-GGA-186798 GAP binds to PDGF-beta receptors only IEA Gallus gallus A0A1D5NU66 R-GGA-186800 https://reactome.org/PathwayBrowser/#/R-GGA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Gallus gallus A0A1D5NU66 R-GGA-186819 https://reactome.org/PathwayBrowser/#/R-GGA-186819 SH2 domain of Src binds to the active receptor IEA Gallus gallus A0A1D5NU66 R-GGA-186826 https://reactome.org/PathwayBrowser/#/R-GGA-186826 GRB2:SOS1 complex binds to the active receptor IEA Gallus gallus A0A1D5NU66 R-GGA-186834 https://reactome.org/PathwayBrowser/#/R-GGA-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Gallus gallus A0A1D5NU66 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5NU66 R-GGA-380780 https://reactome.org/PathwayBrowser/#/R-GGA-380780 Activation of Src IEA Gallus gallus A0A1D5NU66 R-GGA-380782 https://reactome.org/PathwayBrowser/#/R-GGA-380782 STAT binds to the active receptor IEA Gallus gallus A0A1D5NU66 R-GGA-382052 https://reactome.org/PathwayBrowser/#/R-GGA-382052 p130Cas and C3G bind PDGFR bound Crk IEA Gallus gallus A0A1D5NU66 R-GGA-382056 https://reactome.org/PathwayBrowser/#/R-GGA-382056 Crk binds to the active PDGF receptor IEA Gallus gallus A0A1D5NU66 R-GGA-382058 https://reactome.org/PathwayBrowser/#/R-GGA-382058 Nck binds to the active PDGF receptor IEA Gallus gallus A0A1D5NU66 R-GGA-389086 https://reactome.org/PathwayBrowser/#/R-GGA-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Gallus gallus A0A1D5NU66 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5NU66 R-GGA-8864036 https://reactome.org/PathwayBrowser/#/R-GGA-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Gallus gallus A0A1D5NU66 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus A0A1D5NU70 R-GGA-9018758 https://reactome.org/PathwayBrowser/#/R-GGA-9018758 RHOH binds effectors at the plasma membrane IEA Gallus gallus A0A1D5NU78 R-GGA-1678742 https://reactome.org/PathwayBrowser/#/R-GGA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Gallus gallus A0A1D5NU78 R-GGA-2090038 https://reactome.org/PathwayBrowser/#/R-GGA-2090038 NAGLU hydrolyses heparan chain(2) IEA Gallus gallus A0A1D5NU82 R-GGA-2574840 https://reactome.org/PathwayBrowser/#/R-GGA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Gallus gallus A0A1D5NU82 R-GGA-2574845 https://reactome.org/PathwayBrowser/#/R-GGA-2574845 AJUBA binds centrosome-associated AURKA IEA Gallus gallus A0A1D5NU82 R-GGA-3000310 https://reactome.org/PathwayBrowser/#/R-GGA-3000310 AURKA phosphorylates PLK1 IEA Gallus gallus A0A1D5NU82 R-GGA-3000319 https://reactome.org/PathwayBrowser/#/R-GGA-3000319 BORA binds PLK1 and AURKA IEA Gallus gallus A0A1D5NU82 R-GGA-380272 https://reactome.org/PathwayBrowser/#/R-GGA-380272 Plk1-mediated phosphorylation of Nlp IEA Gallus gallus A0A1D5NU82 R-GGA-380283 https://reactome.org/PathwayBrowser/#/R-GGA-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Gallus gallus A0A1D5NU82 R-GGA-380294 https://reactome.org/PathwayBrowser/#/R-GGA-380294 Loss of C-Nap-1 from centrosomes IEA Gallus gallus A0A1D5NU82 R-GGA-380311 https://reactome.org/PathwayBrowser/#/R-GGA-380311 Recruitment of Plk1 to centrosomes IEA Gallus gallus A0A1D5NU82 R-GGA-380455 https://reactome.org/PathwayBrowser/#/R-GGA-380455 Recruitment of CDK11p58 to the centrosomes IEA Gallus gallus A0A1D5NU82 R-GGA-380508 https://reactome.org/PathwayBrowser/#/R-GGA-380508 Translocation of NuMA to the centrosomes IEA Gallus gallus A0A1D5NU82 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5NU82 R-GGA-5626228 https://reactome.org/PathwayBrowser/#/R-GGA-5626228 The distal appendage proteins recruit TTBK2 IEA Gallus gallus A0A1D5NU82 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1D5NU82 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1D5NU82 R-GGA-8853405 https://reactome.org/PathwayBrowser/#/R-GGA-8853405 TPX2 binds AURKA at centrosomes IEA Gallus gallus A0A1D5NU82 R-GGA-8853419 https://reactome.org/PathwayBrowser/#/R-GGA-8853419 TPX2 promotes AURKA autophosphorylation IEA Gallus gallus A0A1D5NU93 R-GGA-77068 https://reactome.org/PathwayBrowser/#/R-GGA-77068 Activation of GT IEA Gallus gallus A0A1D5NU93 R-GGA-77069 https://reactome.org/PathwayBrowser/#/R-GGA-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Gallus gallus A0A1D5NU93 R-GGA-77077 https://reactome.org/PathwayBrowser/#/R-GGA-77077 Capping complex formation IEA Gallus gallus A0A1D5NU93 R-GGA-77078 https://reactome.org/PathwayBrowser/#/R-GGA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Gallus gallus A0A1D5NU93 R-GGA-77081 https://reactome.org/PathwayBrowser/#/R-GGA-77081 Formation of the CE:GMP intermediate complex IEA Gallus gallus A0A1D5NU93 R-GGA-77083 https://reactome.org/PathwayBrowser/#/R-GGA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Gallus gallus A0A1D5NU93 R-GGA-77085 https://reactome.org/PathwayBrowser/#/R-GGA-77085 Dissociation of transcript with 5'-GMP from GT IEA Gallus gallus A0A1D5NUA1 R-GGA-388824 https://reactome.org/PathwayBrowser/#/R-GGA-388824 PTPRF, PTPRS, PTPRD bind Liprins IEA Gallus gallus A0A1D5NUC4 R-GGA-202510 https://reactome.org/PathwayBrowser/#/R-GGA-202510 Activation of TAK1-TAB2 complex IEA Gallus gallus A0A1D5NUC4 R-GGA-2730861 https://reactome.org/PathwayBrowser/#/R-GGA-2730861 Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 IEA Gallus gallus A0A1D5NUC4 R-GGA-2730900 https://reactome.org/PathwayBrowser/#/R-GGA-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Gallus gallus A0A1D5NUC4 R-GGA-4332356 https://reactome.org/PathwayBrowser/#/R-GGA-4332356 CAMK2 binds MAP3K7 IEA Gallus gallus A0A1D5NUC4 R-GGA-4411402 https://reactome.org/PathwayBrowser/#/R-GGA-4411402 Activation of NLK IEA Gallus gallus A0A1D5NUC4 R-GGA-450337 https://reactome.org/PathwayBrowser/#/R-GGA-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Gallus gallus A0A1D5NUC4 R-GGA-450346 https://reactome.org/PathwayBrowser/#/R-GGA-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Gallus gallus A0A1D5NUC4 R-GGA-5607732 https://reactome.org/PathwayBrowser/#/R-GGA-5607732 K63polyUb-TAK1 autophosphorylates IEA Gallus gallus A0A1D5NUC4 R-GGA-5607759 https://reactome.org/PathwayBrowser/#/R-GGA-5607759 TRIKA2 binds K63polyUb-TRAF6 oligomer IEA Gallus gallus A0A1D5NUC4 R-GGA-5696534 https://reactome.org/PathwayBrowser/#/R-GGA-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Gallus gallus A0A1D5NUC4 R-GGA-727819 https://reactome.org/PathwayBrowser/#/R-GGA-727819 TAK1 phosphorylates MKK6 IEA Gallus gallus A0A1D5NUC4 R-GGA-936947 https://reactome.org/PathwayBrowser/#/R-GGA-936947 Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex IEA Gallus gallus A0A1D5NUC4 R-GGA-936951 https://reactome.org/PathwayBrowser/#/R-GGA-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Gallus gallus A0A1D5NUC4 R-GGA-936960 https://reactome.org/PathwayBrowser/#/R-GGA-936960 Activated TRAF6:p-IRAK2 interacts with TAK1 complex IEA Gallus gallus A0A1D5NUC4 R-GGA-936991 https://reactome.org/PathwayBrowser/#/R-GGA-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Gallus gallus A0A1D5NUC4 R-GGA-937075 https://reactome.org/PathwayBrowser/#/R-GGA-937075 Phosphorylated TAK1 leaves activated TLR receptor complex IEA Gallus gallus A0A1D5NUC4 R-GGA-9645406 https://reactome.org/PathwayBrowser/#/R-GGA-9645406 ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) IEA Gallus gallus A0A1D5NUC4 R-GGA-9645442 https://reactome.org/PathwayBrowser/#/R-GGA-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Gallus gallus A0A1D5NUC4 R-GGA-975097 https://reactome.org/PathwayBrowser/#/R-GGA-975097 Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation IEA Gallus gallus A0A1D5NUC4 R-GGA-975103 https://reactome.org/PathwayBrowser/#/R-GGA-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Gallus gallus A0A1D5NUC6 R-GGA-212380 https://reactome.org/PathwayBrowser/#/R-GGA-212380 Formation of TRAP coactivator complex IEA Gallus gallus A0A1D5NUC6 R-GGA-9843120 https://reactome.org/PathwayBrowser/#/R-GGA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1D5NUC7 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5NUC7 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1D5NUC7 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1D5NUC9 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1D5NUC9 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1D5NUC9 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1D5NUC9 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1D5NUC9 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1D5NUC9 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5NUC9 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5NUD0 R-GGA-742354 https://reactome.org/PathwayBrowser/#/R-GGA-742354 SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen IEA Gallus gallus A0A1D5NUD0 R-GGA-742373 https://reactome.org/PathwayBrowser/#/R-GGA-742373 SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen IEA Gallus gallus A0A1D5NUD1 R-GGA-8952630 https://reactome.org/PathwayBrowser/#/R-GGA-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NUD1 R-GGA-8952631 https://reactome.org/PathwayBrowser/#/R-GGA-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NUD1 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5NUD1 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5NUD1 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5NUD1 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5NUD1 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5NUD1 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5NUE9 R-GGA-5668932 https://reactome.org/PathwayBrowser/#/R-GGA-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Gallus gallus A0A1D5NUH1 R-GGA-9018766 https://reactome.org/PathwayBrowser/#/R-GGA-9018766 RHOU binds effectors at the plasma membrane IEA Gallus gallus A0A1D5NUH1 R-GGA-9018778 https://reactome.org/PathwayBrowser/#/R-GGA-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Gallus gallus A0A1D5NUH1 R-GGA-9018787 https://reactome.org/PathwayBrowser/#/R-GGA-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Gallus gallus A0A1D5NUH1 R-GGA-9018794 https://reactome.org/PathwayBrowser/#/R-GGA-9018794 RHOV binds effectors at the plasma membrane IEA Gallus gallus A0A1D5NUH1 R-GGA-9696266 https://reactome.org/PathwayBrowser/#/R-GGA-9696266 RND2 binds effectors IEA Gallus gallus A0A1D5NUH1 R-GGA-9696268 https://reactome.org/PathwayBrowser/#/R-GGA-9696268 RND3 binds effectors IEA Gallus gallus A0A1D5NUH1 R-GGA-9696271 https://reactome.org/PathwayBrowser/#/R-GGA-9696271 RND1 binds effectors IEA Gallus gallus A0A1D5NUH3 R-GGA-1549526 https://reactome.org/PathwayBrowser/#/R-GGA-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Gallus gallus A0A1D5NUH3 R-GGA-170835 https://reactome.org/PathwayBrowser/#/R-GGA-170835 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 IEA Gallus gallus A0A1D5NUH3 R-GGA-170850 https://reactome.org/PathwayBrowser/#/R-GGA-170850 Phosphorylated SMAD2/3 dissociates from TGFBR IEA Gallus gallus A0A1D5NUH3 R-GGA-170868 https://reactome.org/PathwayBrowser/#/R-GGA-170868 Activated type I receptor phosphorylates SMAD2/3 directly IEA Gallus gallus A0A1D5NUH3 R-GGA-173542 https://reactome.org/PathwayBrowser/#/R-GGA-173542 SMURF2 ubiquitinates SMAD2 IEA Gallus gallus A0A1D5NUH3 R-GGA-2176445 https://reactome.org/PathwayBrowser/#/R-GGA-2176445 SMURF2 binds SMAD2 IEA Gallus gallus A0A1D5NUH3 R-GGA-2176452 https://reactome.org/PathwayBrowser/#/R-GGA-2176452 Degradation of ubiquitinated SMAD2 IEA Gallus gallus A0A1D5NUH3 R-GGA-2187355 https://reactome.org/PathwayBrowser/#/R-GGA-2187355 PMEPA1 sequesters phosphorylated SMAD2/3 IEA Gallus gallus A0A1D5NUH3 R-GGA-2187358 https://reactome.org/PathwayBrowser/#/R-GGA-2187358 PMEPA1 sequesters unphosphorylated SMAD2/3 IEA Gallus gallus A0A1D5NUH3 R-GGA-2187395 https://reactome.org/PathwayBrowser/#/R-GGA-2187395 Dephosphorylated SMAD2/3 translocates to the cytosol IEA Gallus gallus A0A1D5NUH3 R-GGA-2187401 https://reactome.org/PathwayBrowser/#/R-GGA-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Gallus gallus A0A1D5NUH3 R-GGA-2187405 https://reactome.org/PathwayBrowser/#/R-GGA-2187405 MTMR4 binds phosphorylated SMAD2/3 IEA Gallus gallus A0A1D5NUH3 R-GGA-6781764 https://reactome.org/PathwayBrowser/#/R-GGA-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Gallus gallus A0A1D5NUH3 R-GGA-9731111 https://reactome.org/PathwayBrowser/#/R-GGA-9731111 MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 IEA Gallus gallus A0A1D5NUH4 R-GGA-375405 https://reactome.org/PathwayBrowser/#/R-GGA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Gallus gallus A0A1D5NUH4 R-GGA-375417 https://reactome.org/PathwayBrowser/#/R-GGA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Gallus gallus A0A1D5NUI1 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1D5NUI1 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1D5NUI1 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1D5NUI1 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1D5NUI1 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1D5NUI1 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5NUI1 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5NUJ3 R-GGA-5693153 https://reactome.org/PathwayBrowser/#/R-GGA-5693153 PPM1K dephosphorylates p-BCKDH IEA Gallus gallus A0A1D5NUJ3 R-GGA-9859148 https://reactome.org/PathwayBrowser/#/R-GGA-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Gallus gallus A0A1D5NUJ3 R-GGA-9859163 https://reactome.org/PathwayBrowser/#/R-GGA-9859163 DBT transfers BCAA to CoA IEA Gallus gallus A0A1D5NUJ3 R-GGA-9859172 https://reactome.org/PathwayBrowser/#/R-GGA-9859172 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus A0A1D5NUK5 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5NUK5 R-GGA-74213 https://reactome.org/PathwayBrowser/#/R-GGA-74213 APRT catalyzes the conversion of adenine to AMP IEA Gallus gallus A0A1D5NUL1 R-GGA-8876446 https://reactome.org/PathwayBrowser/#/R-GGA-8876446 p-ULK1 phosphorylates DENND3 IEA Gallus gallus A0A1D5NUL1 R-GGA-8876454 https://reactome.org/PathwayBrowser/#/R-GGA-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Gallus gallus A0A1D5NUQ3 R-GGA-8952044 https://reactome.org/PathwayBrowser/#/R-GGA-8952044 AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NUQ3 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5NUQ3 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5NUQ3 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5NUQ3 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5NUQ3 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5NUQ3 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5NUQ4 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1D5NUQ4 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1D5NUQ4 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1D5NUQ4 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1D5NUQ4 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1D5NUQ4 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5NUQ4 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5NUQ6 R-GGA-8949649 https://reactome.org/PathwayBrowser/#/R-GGA-8949649 PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) IEA Gallus gallus A0A1D5NUQ6 R-GGA-8949659 https://reactome.org/PathwayBrowser/#/R-GGA-8949659 AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU IEA Gallus gallus A0A1D5NUQ6 R-GGA-8949661 https://reactome.org/PathwayBrowser/#/R-GGA-8949661 C2orf47:AFG3L2 binds the transit peptide of SMDT1 IEA Gallus gallus A0A1D5NUQ7 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5NUR5 R-GGA-9913339 https://reactome.org/PathwayBrowser/#/R-GGA-9913339 Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC IEA Gallus gallus A0A1D5NUR6 R-GGA-5610767 https://reactome.org/PathwayBrowser/#/R-GGA-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Gallus gallus A0A1D5NUR6 R-GGA-5624949 https://reactome.org/PathwayBrowser/#/R-GGA-5624949 Assembly of the anterograde IFT train IEA Gallus gallus A0A1D5NUR6 R-GGA-5625416 https://reactome.org/PathwayBrowser/#/R-GGA-5625416 Anterograde IFT IEA Gallus gallus A0A1D5NUR6 R-GGA-5625426 https://reactome.org/PathwayBrowser/#/R-GGA-5625426 Retrograde IFT IEA Gallus gallus A0A1D5NUT5 R-GGA-376419 https://reactome.org/PathwayBrowser/#/R-GGA-376419 Formation of NR-MED1 Coactivator Complex IEA Gallus gallus A0A1D5NUT5 R-GGA-382096 https://reactome.org/PathwayBrowser/#/R-GGA-382096 Formation of NR-NCOR Corepressor Complex IEA Gallus gallus A0A1D5NUU0 R-GGA-111966 https://reactome.org/PathwayBrowser/#/R-GGA-111966 GRK2 binds CALM1:4Ca2+ IEA Gallus gallus A0A1D5NUU0 R-GGA-111970 https://reactome.org/PathwayBrowser/#/R-GGA-111970 PKC phosphorylates GRK2 IEA Gallus gallus A0A1D5NUU0 R-GGA-416516 https://reactome.org/PathwayBrowser/#/R-GGA-416516 GRK2 sequesters activated Gq IEA Gallus gallus A0A1D5NUU0 R-GGA-5633040 https://reactome.org/PathwayBrowser/#/R-GGA-5633040 CSNK1A1 and ADRBK1 dissociate from p-SMO dimer IEA Gallus gallus A0A1D5NUU0 R-GGA-8851797 https://reactome.org/PathwayBrowser/#/R-GGA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Gallus gallus A0A1D5NUU0 R-GGA-8982641 https://reactome.org/PathwayBrowser/#/R-GGA-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Gallus gallus A0A1D5NUU0 R-GGA-8982645 https://reactome.org/PathwayBrowser/#/R-GGA-8982645 GRKs bind ADRB2:Catecholamine IEA Gallus gallus A0A1D5NUV0 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5NUY2 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5NUY2 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5NUY2 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus A0A1D5NUY2 R-GGA-984606 https://reactome.org/PathwayBrowser/#/R-GGA-984606 Kinesin-5 is a homotetramer IEA Gallus gallus A0A1D5NUY6 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus A0A1D5NUY6 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5NUY6 R-GGA-6799178 https://reactome.org/PathwayBrowser/#/R-GGA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Gallus gallus A0A1D5NUY6 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus A0A1D5NUY6 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus A0A1D5NUY6 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus A0A1D5NUY6 R-GGA-6799202 https://reactome.org/PathwayBrowser/#/R-GGA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Gallus gallus A0A1D5NUZ0 R-GGA-5694423 https://reactome.org/PathwayBrowser/#/R-GGA-5694423 NSF and SNAPs bind cis-SNARE complex IEA Gallus gallus A0A1D5NUZ0 R-GGA-5694425 https://reactome.org/PathwayBrowser/#/R-GGA-5694425 NSF ATPase activity dissociates cis-SNARE IEA Gallus gallus A0A1D5NUZ0 R-GGA-6809014 https://reactome.org/PathwayBrowser/#/R-GGA-6809014 cis-Golgi cis-SNARE binds NSF and SNAPs IEA Gallus gallus A0A1D5NUZ0 R-GGA-6809015 https://reactome.org/PathwayBrowser/#/R-GGA-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Gallus gallus A0A1D5NUZ0 R-GGA-6811422 https://reactome.org/PathwayBrowser/#/R-GGA-6811422 NSF ATPase activity dissociates cis-SNARE at the ER IEA Gallus gallus A0A1D5NUZ0 R-GGA-6811425 https://reactome.org/PathwayBrowser/#/R-GGA-6811425 NSF and SNAPs bind cis-SNARE at the ER membrane IEA Gallus gallus A0A1D5NUZ0 R-GGA-6814676 https://reactome.org/PathwayBrowser/#/R-GGA-6814676 SNAPs and NSF hexamer bind cis-SNARE at the TGN IEA Gallus gallus A0A1D5NUZ0 R-GGA-6814683 https://reactome.org/PathwayBrowser/#/R-GGA-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN IEA Gallus gallus A0A1D5NUZ0 R-GGA-6814684 https://reactome.org/PathwayBrowser/#/R-GGA-6814684 cis-SNARE binds SNAPs and NSF hexamer at the TGN IEA Gallus gallus A0A1D5NUZ0 R-GGA-8847637 https://reactome.org/PathwayBrowser/#/R-GGA-8847637 NSF and SNAPs bind the cis-SNARE at the Golgi IEA Gallus gallus A0A1D5NUZ0 R-GGA-8847638 https://reactome.org/PathwayBrowser/#/R-GGA-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Gallus gallus A0A1D5NUZ4 R-GGA-9851946 https://reactome.org/PathwayBrowser/#/R-GGA-9851946 FIRRM binds PLK1 IEA Gallus gallus A0A1D5NUZ4 R-GGA-9851972 https://reactome.org/PathwayBrowser/#/R-GGA-9851972 PLK1 phosphorylates FIRRM at S43 IEA Gallus gallus A0A1D5NUZ4 R-GGA-9853368 https://reactome.org/PathwayBrowser/#/R-GGA-9853368 FIRRM binds FIGNL1 IEA Gallus gallus A0A1D5NUZ4 R-GGA-9853369 https://reactome.org/PathwayBrowser/#/R-GGA-9853369 PLK1 phosphorylates FIRMM at S744 IEA Gallus gallus A0A1D5NUZ4 R-GGA-9853372 https://reactome.org/PathwayBrowser/#/R-GGA-9853372 FIRRM binds PPP1CC IEA Gallus gallus A0A1D5NUZ4 R-GGA-9853376 https://reactome.org/PathwayBrowser/#/R-GGA-9853376 FIGNL1 binds SPIDR IEA Gallus gallus A0A1D5NUZ4 R-GGA-9853385 https://reactome.org/PathwayBrowser/#/R-GGA-9853385 PPP1CC dephosphorylates PLK1 IEA Gallus gallus A0A1D5NUZ4 R-GGA-9853389 https://reactome.org/PathwayBrowser/#/R-GGA-9853389 FIGNL1 binds RAD51 IEA Gallus gallus A0A1D5NUZ4 R-GGA-9853878 https://reactome.org/PathwayBrowser/#/R-GGA-9853878 FIGNL1 binds DMC1, RAD51 IEA Gallus gallus A0A1D5NV10 R-GGA-9759522 https://reactome.org/PathwayBrowser/#/R-GGA-9759522 Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform IEA Gallus gallus A0A1D5NV15 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus A0A1D5NV36 R-GGA-426155 https://reactome.org/PathwayBrowser/#/R-GGA-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Gallus gallus A0A1D5NV46 R-GGA-75887 https://reactome.org/PathwayBrowser/#/R-GGA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Gallus gallus A0A1D5NV50 R-GGA-192417 https://reactome.org/PathwayBrowser/#/R-GGA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus A0A1D5NV50 R-GGA-192425 https://reactome.org/PathwayBrowser/#/R-GGA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus A0A1D5NV50 R-GGA-192430 https://reactome.org/PathwayBrowser/#/R-GGA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus A0A1D5NV56 R-GGA-204392 https://reactome.org/PathwayBrowser/#/R-GGA-204392 Basigin binds MCT1, MCT3 and MCT4 IEA Gallus gallus A0A1D5NV56 R-GGA-373867 https://reactome.org/PathwayBrowser/#/R-GGA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Gallus gallus A0A1D5NV56 R-GGA-373875 https://reactome.org/PathwayBrowser/#/R-GGA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Gallus gallus A0A1D5NV56 R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus A0A1D5NV65 R-GGA-6787329 https://reactome.org/PathwayBrowser/#/R-GGA-6787329 PGM2:Mg2+ isomerises R1P to R5P IEA Gallus gallus A0A1D5NV65 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5NV65 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5NV65 R-GGA-8982667 https://reactome.org/PathwayBrowser/#/R-GGA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P IEA Gallus gallus A0A1D5NV71 R-GGA-1181149 https://reactome.org/PathwayBrowser/#/R-GGA-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Gallus gallus A0A1D5NV71 R-GGA-1181153 https://reactome.org/PathwayBrowser/#/R-GGA-1181153 Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B IEA Gallus gallus A0A1D5NV71 R-GGA-1549526 https://reactome.org/PathwayBrowser/#/R-GGA-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Gallus gallus A0A1D5NV71 R-GGA-201457 https://reactome.org/PathwayBrowser/#/R-GGA-201457 BMP2 binds to the receptor complex IEA Gallus gallus A0A1D5NV71 R-GGA-2473184 https://reactome.org/PathwayBrowser/#/R-GGA-2473184 Follistatin (FST) binds Activin IEA Gallus gallus A0A1D5NV71 R-GGA-2473186 https://reactome.org/PathwayBrowser/#/R-GGA-2473186 FSTL3 binds Activin IEA Gallus gallus A0A1D5NV71 R-GGA-378975 https://reactome.org/PathwayBrowser/#/R-GGA-378975 Follitropin is a heterodimer IEA Gallus gallus A0A1D5NV71 R-GGA-9839384 https://reactome.org/PathwayBrowser/#/R-GGA-9839384 Inhibin-A binding to TGFBR3 IEA Gallus gallus A0A1D5NV71 R-GGA-9839405 https://reactome.org/PathwayBrowser/#/R-GGA-9839405 InhibinA-TGFBR3 binding to ACVR2A IEA Gallus gallus A0A1D5NV93 R-GGA-6783955 https://reactome.org/PathwayBrowser/#/R-GGA-6783955 PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus A0A1D5NV94 R-GGA-177479 https://reactome.org/PathwayBrowser/#/R-GGA-177479 Axonal transport of NGF:Trk complexes IEA Gallus gallus A0A1D5NV94 R-GGA-2130725 https://reactome.org/PathwayBrowser/#/R-GGA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Gallus gallus A0A1D5NV94 R-GGA-392749 https://reactome.org/PathwayBrowser/#/R-GGA-392749 Transport of L1 into endosomes IEA Gallus gallus A0A1D5NV94 R-GGA-3928654 https://reactome.org/PathwayBrowser/#/R-GGA-3928654 Clathrin internalises EPH:EFN complexes IEA Gallus gallus A0A1D5NV94 R-GGA-416639 https://reactome.org/PathwayBrowser/#/R-GGA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Gallus gallus A0A1D5NV94 R-GGA-421007 https://reactome.org/PathwayBrowser/#/R-GGA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5NV94 R-GGA-445079 https://reactome.org/PathwayBrowser/#/R-GGA-445079 Phosphorylation of L1 by ERK IEA Gallus gallus A0A1D5NV94 R-GGA-5140747 https://reactome.org/PathwayBrowser/#/R-GGA-5140747 FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner IEA Gallus gallus A0A1D5NV94 R-GGA-555065 https://reactome.org/PathwayBrowser/#/R-GGA-555065 Formation of clathrin coated vesicle IEA Gallus gallus A0A1D5NV94 R-GGA-6784729 https://reactome.org/PathwayBrowser/#/R-GGA-6784729 PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome IEA Gallus gallus A0A1D5NV94 R-GGA-6784738 https://reactome.org/PathwayBrowser/#/R-GGA-6784738 Degradation of PCSK9:LDLR:Clathrin-coated vesicle IEA Gallus gallus A0A1D5NV94 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5NV94 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1D5NV94 R-GGA-8855130 https://reactome.org/PathwayBrowser/#/R-GGA-8855130 VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane IEA Gallus gallus A0A1D5NV94 R-GGA-8855131 https://reactome.org/PathwayBrowser/#/R-GGA-8855131 VLDLR:PCSK9 binds Clathrin-coated vesicles IEA Gallus gallus A0A1D5NV94 R-GGA-8856813 https://reactome.org/PathwayBrowser/#/R-GGA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Gallus gallus A0A1D5NV94 R-GGA-8866277 https://reactome.org/PathwayBrowser/#/R-GGA-8866277 AP-2 directly binds some endocytic cargo IEA Gallus gallus A0A1D5NV94 R-GGA-8866279 https://reactome.org/PathwayBrowser/#/R-GGA-8866279 Epsin family proteins bind ubiquitinated cargo IEA Gallus gallus A0A1D5NV94 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5NV94 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5NV94 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5NV94 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5NV94 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5NV94 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5NV94 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5NV94 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5NV94 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5NV94 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5NV94 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5NV94 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5NV94 R-GGA-8871196 https://reactome.org/PathwayBrowser/#/R-GGA-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Gallus gallus A0A1D5NV94 R-GGA-9681616 https://reactome.org/PathwayBrowser/#/R-GGA-9681616 AP2 binds chlorpromazine IEA Gallus gallus A0A1D5NV95 R-GGA-174439 https://reactome.org/PathwayBrowser/#/R-GGA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Gallus gallus A0A1D5NV95 R-GGA-174452 https://reactome.org/PathwayBrowser/#/R-GGA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Gallus gallus A0A1D5NV95 R-GGA-9668902 https://reactome.org/PathwayBrowser/#/R-GGA-9668902 Formation of the CTF18-RFC(7s) complex IEA Gallus gallus A0A1D5NV95 R-GGA-9668904 https://reactome.org/PathwayBrowser/#/R-GGA-9668904 Formation of the CTF18 complex IEA Gallus gallus A0A1D5NV99 R-GGA-2514865 https://reactome.org/PathwayBrowser/#/R-GGA-2514865 cGMP dissociates from CNG channels IEA Gallus gallus A0A1D5NV99 R-GGA-2514867 https://reactome.org/PathwayBrowser/#/R-GGA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Gallus gallus A0A1D5NV99 R-GGA-3229181 https://reactome.org/PathwayBrowser/#/R-GGA-3229181 CALM1:Ca2+ binds CNG channel IEA Gallus gallus A0A1D5NV99 R-GGA-74031 https://reactome.org/PathwayBrowser/#/R-GGA-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Gallus gallus A0A1D5NVE0 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5NVE2 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5NVE2 R-GGA-983152 https://reactome.org/PathwayBrowser/#/R-GGA-983152 Transfer of ubiquitin from E1 to E2 IEA Gallus gallus A0A1D5NVE2 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5NVE2 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5NVH5 R-GGA-5696914 https://reactome.org/PathwayBrowser/#/R-GGA-5696914 USP28 deubiquitinates CLSPN and MYC IEA Gallus gallus A0A1D5NVI1 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1D5NVI1 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1D5NVI1 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1D5NVI1 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1D5NVI1 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1D5NVI1 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5NVI1 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5NVI7 R-GGA-376419 https://reactome.org/PathwayBrowser/#/R-GGA-376419 Formation of NR-MED1 Coactivator Complex IEA Gallus gallus A0A1D5NVI7 R-GGA-382096 https://reactome.org/PathwayBrowser/#/R-GGA-382096 Formation of NR-NCOR Corepressor Complex IEA Gallus gallus A0A1D5NVJ0 R-GGA-3232162 https://reactome.org/PathwayBrowser/#/R-GGA-3232162 PIAS3 SUMOylates MITF with SUMO1 IEA Gallus gallus A0A1D5NVJ0 R-GGA-3465545 https://reactome.org/PathwayBrowser/#/R-GGA-3465545 PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 IEA Gallus gallus A0A1D5NVJ0 R-GGA-4086036 https://reactome.org/PathwayBrowser/#/R-GGA-4086036 PIAS1,3 SUMOylate NRIP1 with SUMO1 IEA Gallus gallus A0A1D5NVJ0 R-GGA-4090288 https://reactome.org/PathwayBrowser/#/R-GGA-4090288 PIAS1,3 SUMOylate MBD1 with SUMO1 IEA Gallus gallus A0A1D5NVJ0 R-GGA-4090408 https://reactome.org/PathwayBrowser/#/R-GGA-4090408 PIAS1,3 SUMOylate ESR1 with SUMO1 IEA Gallus gallus A0A1D5NVJ0 R-GGA-4341073 https://reactome.org/PathwayBrowser/#/R-GGA-4341073 PIAS3 SUMOylates PGR with SUMO1 IEA Gallus gallus A0A1D5NVJ0 R-GGA-4546385 https://reactome.org/PathwayBrowser/#/R-GGA-4546385 PIAS1,3 SUMOylates NR5A1 with SUMO2 IEA Gallus gallus A0A1D5NVJ0 R-GGA-4546386 https://reactome.org/PathwayBrowser/#/R-GGA-4546386 PIAS1,3 SUMOylates NR5A1 with SUMO1 IEA Gallus gallus A0A1D5NVJ0 R-GGA-4655355 https://reactome.org/PathwayBrowser/#/R-GGA-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Gallus gallus A0A1D5NVJ0 R-GGA-4719413 https://reactome.org/PathwayBrowser/#/R-GGA-4719413 PIAS2,3,4 SUMOylate RORA with SUMO2 IEA Gallus gallus A0A1D5NVJ0 R-GGA-4719436 https://reactome.org/PathwayBrowser/#/R-GGA-4719436 PIAS2,3,4 SUMOylate RORA with SUMO1 IEA Gallus gallus A0A1D5NVJ0 R-GGA-4755536 https://reactome.org/PathwayBrowser/#/R-GGA-4755536 PIAS3 SUMOylates RELA with SUMO3 IEA Gallus gallus A0A1D5NVJ0 R-GGA-6790454 https://reactome.org/PathwayBrowser/#/R-GGA-6790454 SUMOylation of XPC IEA Gallus gallus A0A1D5NVK1 R-GGA-9021072 https://reactome.org/PathwayBrowser/#/R-GGA-9021072 ZDHHC7, ZDHHC21 palmitoylate ESR1 IEA Gallus gallus A0A1D5NVK3 R-GGA-163809 https://reactome.org/PathwayBrowser/#/R-GGA-163809 Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus IEA Gallus gallus A0A1D5NVK3 R-GGA-163843 https://reactome.org/PathwayBrowser/#/R-GGA-163843 Furin cleaves pro-GAS6 to GAS6 IEA Gallus gallus A0A1D5NVK3 R-GGA-202710 https://reactome.org/PathwayBrowser/#/R-GGA-202710 MERTK receptor binds ligands (Gas6 or Protein S) IEA Gallus gallus A0A1D5NVK3 R-GGA-481007 https://reactome.org/PathwayBrowser/#/R-GGA-481007 Exocytosis of platelet alpha granule contents IEA Gallus gallus A0A1D5NVK3 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5NVK9 R-GGA-1222376 https://reactome.org/PathwayBrowser/#/R-GGA-1222376 NOX2 generates superoxide from oxygen IEA Gallus gallus A0A1D5NVK9 R-GGA-1236967 https://reactome.org/PathwayBrowser/#/R-GGA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Gallus gallus A0A1D5NVK9 R-GGA-5218827 https://reactome.org/PathwayBrowser/#/R-GGA-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Gallus gallus A0A1D5NVK9 R-GGA-5218841 https://reactome.org/PathwayBrowser/#/R-GGA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Gallus gallus A0A1D5NVK9 R-GGA-5668605 https://reactome.org/PathwayBrowser/#/R-GGA-5668605 RAC2:GTP binds NOX2 complex IEA Gallus gallus A0A1D5NVK9 R-GGA-5668629 https://reactome.org/PathwayBrowser/#/R-GGA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Gallus gallus A0A1D5NVK9 R-GGA-6789092 https://reactome.org/PathwayBrowser/#/R-GGA-6789092 NOX2 generates superoxide anion from oxygen IEA Gallus gallus A0A1D5NVK9 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5NVK9 R-GGA-9014424 https://reactome.org/PathwayBrowser/#/R-GGA-9014424 RAC2 binds effectors at the phagocytic vesicle membrane IEA Gallus gallus A0A1D5NVK9 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5NVK9 R-GGA-9626816 https://reactome.org/PathwayBrowser/#/R-GGA-9626816 PIN1 binds p-S345-NCF1 IEA Gallus gallus A0A1D5NVK9 R-GGA-9626817 https://reactome.org/PathwayBrowser/#/R-GGA-9626817 PKC phosphorylates NCF1 IEA Gallus gallus A0A1D5NVK9 R-GGA-9626832 https://reactome.org/PathwayBrowser/#/R-GGA-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Gallus gallus A0A1D5NVK9 R-GGA-9626848 https://reactome.org/PathwayBrowser/#/R-GGA-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Gallus gallus A0A1D5NVK9 R-GGA-9626880 https://reactome.org/PathwayBrowser/#/R-GGA-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Gallus gallus A0A1D5NVM2 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus A0A1D5NVM2 R-GGA-6799178 https://reactome.org/PathwayBrowser/#/R-GGA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Gallus gallus A0A1D5NVM2 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus A0A1D5NVM2 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus A0A1D5NVM2 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus A0A1D5NVM2 R-GGA-6799202 https://reactome.org/PathwayBrowser/#/R-GGA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Gallus gallus A0A1D5NVM2 R-GGA-9837978 https://reactome.org/PathwayBrowser/#/R-GGA-9837978 LONP1 binds mitochondrial inner membrane proteins IEA Gallus gallus A0A1D5NVM2 R-GGA-9838004 https://reactome.org/PathwayBrowser/#/R-GGA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Gallus gallus A0A1D5NVM6 R-GGA-917696 https://reactome.org/PathwayBrowser/#/R-GGA-917696 Cargo Sequestration IEA Gallus gallus A0A1D5NVM6 R-GGA-917730 https://reactome.org/PathwayBrowser/#/R-GGA-917730 Cargo Recognition And Sorting IEA Gallus gallus A0A1D5NVP0 R-GGA-168162 https://reactome.org/PathwayBrowser/#/R-GGA-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Gallus gallus A0A1D5NVP0 R-GGA-2730896 https://reactome.org/PathwayBrowser/#/R-GGA-2730896 Phosphorylation of MEK4 by MEKK1 IEA Gallus gallus A0A1D5NVP0 R-GGA-450337 https://reactome.org/PathwayBrowser/#/R-GGA-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Gallus gallus A0A1D5NVP9 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus A0A1D5NVP9 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus A0A1D5NVP9 R-GGA-9013159 https://reactome.org/PathwayBrowser/#/R-GGA-9013159 CDC42 GEFs activate CDC42 IEA Gallus gallus A0A1D5NVQ5 R-GGA-2029451 https://reactome.org/PathwayBrowser/#/R-GGA-2029451 Activation of RAC1 by VAV IEA Gallus gallus A0A1D5NVQ5 R-GGA-2029453 https://reactome.org/PathwayBrowser/#/R-GGA-2029453 Phosphorylation of VAV IEA Gallus gallus A0A1D5NVQ5 R-GGA-2029458 https://reactome.org/PathwayBrowser/#/R-GGA-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Gallus gallus A0A1D5NVQ5 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus A0A1D5NVQ5 R-GGA-2424476 https://reactome.org/PathwayBrowser/#/R-GGA-2424476 Activation of RAC1 by VAV2/3 IEA Gallus gallus A0A1D5NVQ5 R-GGA-2424481 https://reactome.org/PathwayBrowser/#/R-GGA-2424481 Recruitment of VAV and BTK to p-SLP-76 IEA Gallus gallus A0A1D5NVQ5 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus A0A1D5NVQ5 R-GGA-2424485 https://reactome.org/PathwayBrowser/#/R-GGA-2424485 Release of p-PLCG1 IEA Gallus gallus A0A1D5NVQ5 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus A0A1D5NVQ5 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus A0A1D5NVQ5 R-GGA-2730840 https://reactome.org/PathwayBrowser/#/R-GGA-2730840 Activation of RAC1 by VAV IEA Gallus gallus A0A1D5NVQ5 R-GGA-2730841 https://reactome.org/PathwayBrowser/#/R-GGA-2730841 Phosphorylation and activation of VAV IEA Gallus gallus A0A1D5NVQ5 R-GGA-2730847 https://reactome.org/PathwayBrowser/#/R-GGA-2730847 Hydrolysis of PIP2 by PLCG IEA Gallus gallus A0A1D5NVQ5 R-GGA-2730856 https://reactome.org/PathwayBrowser/#/R-GGA-2730856 Autophosphorylation of PAK IEA Gallus gallus A0A1D5NVQ5 R-GGA-2730858 https://reactome.org/PathwayBrowser/#/R-GGA-2730858 Autophosphorylation of BTK/ITK IEA Gallus gallus A0A1D5NVQ5 R-GGA-2730889 https://reactome.org/PathwayBrowser/#/R-GGA-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Gallus gallus A0A1D5NVQ5 R-GGA-2730892 https://reactome.org/PathwayBrowser/#/R-GGA-2730892 Recruitment of VAV to p-SLP-76 IEA Gallus gallus A0A1D5NVQ5 R-GGA-3928604 https://reactome.org/PathwayBrowser/#/R-GGA-3928604 SFKs phosphorylate VAV2,3 IEA Gallus gallus A0A1D5NVQ5 R-GGA-3928607 https://reactome.org/PathwayBrowser/#/R-GGA-3928607 p-EPHs bind VAV2,3 IEA Gallus gallus A0A1D5NVQ5 R-GGA-3928628 https://reactome.org/PathwayBrowser/#/R-GGA-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5NVQ5 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus A0A1D5NVQ5 R-GGA-430158 https://reactome.org/PathwayBrowser/#/R-GGA-430158 p-SLP-76 binds VAV IEA Gallus gallus A0A1D5NVQ5 R-GGA-442291 https://reactome.org/PathwayBrowser/#/R-GGA-442291 VAV2 is a GEF for Rho/Rac family kinases IEA Gallus gallus A0A1D5NVQ5 R-GGA-445064 https://reactome.org/PathwayBrowser/#/R-GGA-445064 Activation of Rac1 by VAV2 IEA Gallus gallus A0A1D5NVQ5 R-GGA-5218820 https://reactome.org/PathwayBrowser/#/R-GGA-5218820 Src kinases phosphorylate VAV IEA Gallus gallus A0A1D5NVQ5 R-GGA-5218850 https://reactome.org/PathwayBrowser/#/R-GGA-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5NVQ5 R-GGA-5357445 https://reactome.org/PathwayBrowser/#/R-GGA-5357445 PAK1-3 dimer disassociates IEA Gallus gallus A0A1D5NVQ5 R-GGA-5357472 https://reactome.org/PathwayBrowser/#/R-GGA-5357472 PAK1-3 autophosphorylates IEA Gallus gallus A0A1D5NVQ5 R-GGA-5357483 https://reactome.org/PathwayBrowser/#/R-GGA-5357483 RAC1 binds PAK1-3 IEA Gallus gallus A0A1D5NVQ5 R-GGA-8951586 https://reactome.org/PathwayBrowser/#/R-GGA-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Gallus gallus A0A1D5NVQ5 R-GGA-8980691 https://reactome.org/PathwayBrowser/#/R-GGA-8980691 RHOA GEFs activate RHOA IEA Gallus gallus A0A1D5NVQ5 R-GGA-9013023 https://reactome.org/PathwayBrowser/#/R-GGA-9013023 RHOB GEFs activate RHOB IEA Gallus gallus A0A1D5NVQ5 R-GGA-9013109 https://reactome.org/PathwayBrowser/#/R-GGA-9013109 RHOC GEFs activate RHOC IEA Gallus gallus A0A1D5NVQ5 R-GGA-9013143 https://reactome.org/PathwayBrowser/#/R-GGA-9013143 RAC1 GEFs activate RAC1 IEA Gallus gallus A0A1D5NVQ5 R-GGA-9013159 https://reactome.org/PathwayBrowser/#/R-GGA-9013159 CDC42 GEFs activate CDC42 IEA Gallus gallus A0A1D5NVQ5 R-GGA-9014296 https://reactome.org/PathwayBrowser/#/R-GGA-9014296 RAC2 GEFs activate RAC2 IEA Gallus gallus A0A1D5NVQ5 R-GGA-9014433 https://reactome.org/PathwayBrowser/#/R-GGA-9014433 RHOG GEFs activate RHOG IEA Gallus gallus A0A1D5NVQ5 R-GGA-9018804 https://reactome.org/PathwayBrowser/#/R-GGA-9018804 RAC3 GEFs activate RAC3 IEA Gallus gallus A0A1D5NVQ5 R-GGA-9751201 https://reactome.org/PathwayBrowser/#/R-GGA-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Gallus gallus A0A1D5NVR2 R-GGA-1168445 https://reactome.org/PathwayBrowser/#/R-GGA-1168445 PTP1B binds the GH receptor complex IEA Gallus gallus A0A1D5NVR2 R-GGA-1168459 https://reactome.org/PathwayBrowser/#/R-GGA-1168459 Lyn activates ERK IEA Gallus gallus A0A1D5NVR2 R-GGA-1168894 https://reactome.org/PathwayBrowser/#/R-GGA-1168894 p-STAT5A/B dissociates from the Growth Hormone receptor IEA Gallus gallus A0A1D5NVR2 R-GGA-1169192 https://reactome.org/PathwayBrowser/#/R-GGA-1169192 PTP1B dephosphorylates GHR IEA Gallus gallus A0A1D5NVR2 R-GGA-1362465 https://reactome.org/PathwayBrowser/#/R-GGA-1362465 GHBP binds GHR IEA Gallus gallus A0A1D5NVR2 R-GGA-1362485 https://reactome.org/PathwayBrowser/#/R-GGA-1362485 GHBP binds GH IEA Gallus gallus A0A1D5NVR2 R-GGA-982768 https://reactome.org/PathwayBrowser/#/R-GGA-982768 GH:GHR:JAK2 complex undergoes a conformational change IEA Gallus gallus A0A1D5NVR2 R-GGA-982775 https://reactome.org/PathwayBrowser/#/R-GGA-982775 Growth hormone receptor dimerizes IEA Gallus gallus A0A1D5NVR2 R-GGA-982778 https://reactome.org/PathwayBrowser/#/R-GGA-982778 Growth hormone binds the growth hormone receptor IEA Gallus gallus A0A1D5NVR2 R-GGA-982792 https://reactome.org/PathwayBrowser/#/R-GGA-982792 Growth hormone receptor binds JAK2 IEA Gallus gallus A0A1D5NVR2 R-GGA-982807 https://reactome.org/PathwayBrowser/#/R-GGA-982807 JAK2 phosphorylation of GHR IEA Gallus gallus A0A1D5NVR2 R-GGA-982810 https://reactome.org/PathwayBrowser/#/R-GGA-982810 JAK2 phosphorylation IEA Gallus gallus A0A1D5NVS2 R-GGA-419001 https://reactome.org/PathwayBrowser/#/R-GGA-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Gallus gallus A0A1D5NVS2 R-GGA-419002 https://reactome.org/PathwayBrowser/#/R-GGA-419002 Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin IEA Gallus gallus A0A1D5NVS8 R-GGA-3321883 https://reactome.org/PathwayBrowser/#/R-GGA-3321883 MSL acetylates histone H4 IEA Gallus gallus A0A1D5NVT2 R-GGA-2046222 https://reactome.org/PathwayBrowser/#/R-GGA-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG IEA Gallus gallus A0A1D5NVU2 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5NVU2 R-GGA-6805546 https://reactome.org/PathwayBrowser/#/R-GGA-6805546 Keratin type I binds keratin type II IEA Gallus gallus A0A1D5NVU2 R-GGA-6805573 https://reactome.org/PathwayBrowser/#/R-GGA-6805573 Keratin type I/type II heterodimers form tetramers IEA Gallus gallus A0A1D5NVU2 R-GGA-6806610 https://reactome.org/PathwayBrowser/#/R-GGA-6806610 Keratin filament formation IEA Gallus gallus A0A1D5NVU2 R-GGA-6806613 https://reactome.org/PathwayBrowser/#/R-GGA-6806613 Keratin tetramers bind to form unit length filaments IEA Gallus gallus A0A1D5NVU2 R-GGA-6806629 https://reactome.org/PathwayBrowser/#/R-GGA-6806629 Formation of tonofilament bundles IEA Gallus gallus A0A1D5NVU2 R-GGA-6809393 https://reactome.org/PathwayBrowser/#/R-GGA-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Gallus gallus A0A1D5NVU2 R-GGA-6810357 https://reactome.org/PathwayBrowser/#/R-GGA-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Gallus gallus A0A1D5NVU6 R-GGA-5617815 https://reactome.org/PathwayBrowser/#/R-GGA-5617815 BBSome binds RAB3IP IEA Gallus gallus A0A1D5NVU6 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5NVU6 R-GGA-5623519 https://reactome.org/PathwayBrowser/#/R-GGA-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Gallus gallus A0A1D5NVU6 R-GGA-5623521 https://reactome.org/PathwayBrowser/#/R-GGA-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5NVU6 R-GGA-5623524 https://reactome.org/PathwayBrowser/#/R-GGA-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Gallus gallus A0A1D5NVU6 R-GGA-5623525 https://reactome.org/PathwayBrowser/#/R-GGA-5623525 Cargo-carrying vesicles bud from the TGN IEA Gallus gallus A0A1D5NVU6 R-GGA-5623527 https://reactome.org/PathwayBrowser/#/R-GGA-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Gallus gallus A0A1D5NVU6 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1D5NVU6 R-GGA-5638014 https://reactome.org/PathwayBrowser/#/R-GGA-5638014 RAB11A:GTP-containing Golgi vesicles recruit RAB3IP IEA Gallus gallus A0A1D5NVU6 R-GGA-8876190 https://reactome.org/PathwayBrowser/#/R-GGA-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Gallus gallus A0A1D5NVX6 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1D5NVX6 R-GGA-388529 https://reactome.org/PathwayBrowser/#/R-GGA-388529 Cholecystokinin receptors bind cholecystokinin IEA Gallus gallus A0A1D5NVX6 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1D5NVX6 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1D5NVY0 R-GGA-164832 https://reactome.org/PathwayBrowser/#/R-GGA-164832 ATPase synthesizes ATP IEA Gallus gallus A0A1D5NVY0 R-GGA-164834 https://reactome.org/PathwayBrowser/#/R-GGA-164834 Enzyme-bound ATP is released IEA Gallus gallus A0A1D5NVY0 R-GGA-164840 https://reactome.org/PathwayBrowser/#/R-GGA-164840 ADP and Pi bind to ATPase IEA Gallus gallus A0A1D5NVY0 R-GGA-8949580 https://reactome.org/PathwayBrowser/#/R-GGA-8949580 F1Fo ATP synthase dimerizes IEA Gallus gallus A0A1D5NVZ0 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5NVZ0 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5NVZ0 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5NVZ0 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5NVZ0 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5NW08 R-GGA-158118 https://reactome.org/PathwayBrowser/#/R-GGA-158118 factor VIII + von Willebrand factor multimer -> factor VIII:von Willibrand factor multimer IEA Gallus gallus A0A1D5NW08 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus A0A1D5NW08 R-GGA-158164 https://reactome.org/PathwayBrowser/#/R-GGA-158164 factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst) IEA Gallus gallus A0A1D5NW08 R-GGA-158278 https://reactome.org/PathwayBrowser/#/R-GGA-158278 factor VIIIa + factor IXa -> factor VIIIa:factor IXa IEA Gallus gallus A0A1D5NW08 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus A0A1D5NW08 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus A0A1D5NW08 R-GGA-481007 https://reactome.org/PathwayBrowser/#/R-GGA-481007 Exocytosis of platelet alpha granule contents IEA Gallus gallus A0A1D5NW08 R-GGA-5607002 https://reactome.org/PathwayBrowser/#/R-GGA-5607002 Activated protein C cleaves factor VIIIa IEA Gallus gallus A0A1D5NW08 R-GGA-5607043 https://reactome.org/PathwayBrowser/#/R-GGA-5607043 factor VIIIa associates with cell membrane IEA Gallus gallus A0A1D5NW08 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus A0A1D5NW08 R-GGA-5694417 https://reactome.org/PathwayBrowser/#/R-GGA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Gallus gallus A0A1D5NW08 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus A0A1D5NW08 R-GGA-5694431 https://reactome.org/PathwayBrowser/#/R-GGA-5694431 Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors IEA Gallus gallus A0A1D5NW08 R-GGA-5694446 https://reactome.org/PathwayBrowser/#/R-GGA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Gallus gallus A0A1D5NW08 R-GGA-5694522 https://reactome.org/PathwayBrowser/#/R-GGA-5694522 Inner coat assembly and cargo binding IEA Gallus gallus A0A1D5NW08 R-GGA-5694527 https://reactome.org/PathwayBrowser/#/R-GGA-5694527 Loss of SAR1B GTPase IEA Gallus gallus A0A1D5NW08 R-GGA-9661625 https://reactome.org/PathwayBrowser/#/R-GGA-9661625 FVIII is secreted IEA Gallus gallus A0A1D5NW08 R-GGA-9668023 https://reactome.org/PathwayBrowser/#/R-GGA-9668023 TPST1,2 transfer SO4(2-) from PAPS to FVIII IEA Gallus gallus A0A1D5NW08 R-GGA-9670014 https://reactome.org/PathwayBrowser/#/R-GGA-9670014 Factor VIIIa dissociates IEA Gallus gallus A0A1D5NW22 R-GGA-451634 https://reactome.org/PathwayBrowser/#/R-GGA-451634 NFKB p105, TPL2 (COT) and ABIN2 form a stable complex IEA Gallus gallus A0A1D5NW22 R-GGA-5684248 https://reactome.org/PathwayBrowser/#/R-GGA-5684248 SCF betaTrCP1,2 binds p-NFkB p105:TPL2:ABIN2 IEA Gallus gallus A0A1D5NW22 R-GGA-5684250 https://reactome.org/PathwayBrowser/#/R-GGA-5684250 SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 IEA Gallus gallus A0A1D5NW22 R-GGA-5684261 https://reactome.org/PathwayBrowser/#/R-GGA-5684261 MAP3K8 is phosphorylated IEA Gallus gallus A0A1D5NW22 R-GGA-5684273 https://reactome.org/PathwayBrowser/#/R-GGA-5684273 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 IEA Gallus gallus A0A1D5NW22 R-GGA-5690845 https://reactome.org/PathwayBrowser/#/R-GGA-5690845 TNIPs bind TNFAIP3 (A20) IEA Gallus gallus A0A1D5NW24 R-GGA-76056 https://reactome.org/PathwayBrowser/#/R-GGA-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Gallus gallus A0A1D5NW24 R-GGA-83805 https://reactome.org/PathwayBrowser/#/R-GGA-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Gallus gallus A0A1D5NW27 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5NW27 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5NW27 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5NW27 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5NW27 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5NW27 R-GGA-2574840 https://reactome.org/PathwayBrowser/#/R-GGA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Gallus gallus A0A1D5NW27 R-GGA-2574845 https://reactome.org/PathwayBrowser/#/R-GGA-2574845 AJUBA binds centrosome-associated AURKA IEA Gallus gallus A0A1D5NW27 R-GGA-3000310 https://reactome.org/PathwayBrowser/#/R-GGA-3000310 AURKA phosphorylates PLK1 IEA Gallus gallus A0A1D5NW27 R-GGA-3000319 https://reactome.org/PathwayBrowser/#/R-GGA-3000319 BORA binds PLK1 and AURKA IEA Gallus gallus A0A1D5NW27 R-GGA-380272 https://reactome.org/PathwayBrowser/#/R-GGA-380272 Plk1-mediated phosphorylation of Nlp IEA Gallus gallus A0A1D5NW27 R-GGA-380283 https://reactome.org/PathwayBrowser/#/R-GGA-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Gallus gallus A0A1D5NW27 R-GGA-380294 https://reactome.org/PathwayBrowser/#/R-GGA-380294 Loss of C-Nap-1 from centrosomes IEA Gallus gallus A0A1D5NW27 R-GGA-380311 https://reactome.org/PathwayBrowser/#/R-GGA-380311 Recruitment of Plk1 to centrosomes IEA Gallus gallus A0A1D5NW27 R-GGA-380455 https://reactome.org/PathwayBrowser/#/R-GGA-380455 Recruitment of CDK11p58 to the centrosomes IEA Gallus gallus A0A1D5NW27 R-GGA-380508 https://reactome.org/PathwayBrowser/#/R-GGA-380508 Translocation of NuMA to the centrosomes IEA Gallus gallus A0A1D5NW27 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5NW27 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus A0A1D5NW27 R-GGA-5624949 https://reactome.org/PathwayBrowser/#/R-GGA-5624949 Assembly of the anterograde IFT train IEA Gallus gallus A0A1D5NW27 R-GGA-5625416 https://reactome.org/PathwayBrowser/#/R-GGA-5625416 Anterograde IFT IEA Gallus gallus A0A1D5NW27 R-GGA-5625426 https://reactome.org/PathwayBrowser/#/R-GGA-5625426 Retrograde IFT IEA Gallus gallus A0A1D5NW27 R-GGA-5626228 https://reactome.org/PathwayBrowser/#/R-GGA-5626228 The distal appendage proteins recruit TTBK2 IEA Gallus gallus A0A1D5NW27 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1D5NW27 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1D5NW27 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1D5NW27 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5NW27 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5NW27 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5NW27 R-GGA-8849350 https://reactome.org/PathwayBrowser/#/R-GGA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Gallus gallus A0A1D5NW27 R-GGA-8849353 https://reactome.org/PathwayBrowser/#/R-GGA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Gallus gallus A0A1D5NW27 R-GGA-8853405 https://reactome.org/PathwayBrowser/#/R-GGA-8853405 TPX2 binds AURKA at centrosomes IEA Gallus gallus A0A1D5NW27 R-GGA-8853419 https://reactome.org/PathwayBrowser/#/R-GGA-8853419 TPX2 promotes AURKA autophosphorylation IEA Gallus gallus A0A1D5NW27 R-GGA-9646679 https://reactome.org/PathwayBrowser/#/R-GGA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Gallus gallus A0A1D5NW27 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1D5NW27 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus A0A1D5NW29 R-GGA-481044 https://reactome.org/PathwayBrowser/#/R-GGA-481044 Surface deployment of platelet alpha granule membrane components IEA Gallus gallus A0A1D5NW29 R-GGA-9013009 https://reactome.org/PathwayBrowser/#/R-GGA-9013009 RHOA binds effectors at the plasma membrane IEA Gallus gallus A0A1D5NW29 R-GGA-9013024 https://reactome.org/PathwayBrowser/#/R-GGA-9013024 RHOB binds effectors at the plasma membrane IEA Gallus gallus A0A1D5NW33 R-GGA-375138 https://reactome.org/PathwayBrowser/#/R-GGA-375138 CDO binds BOC IEA Gallus gallus A0A1D5NW33 R-GGA-375140 https://reactome.org/PathwayBrowser/#/R-GGA-375140 CDO binds promyogenic cadherins IEA Gallus gallus A0A1D5NW33 R-GGA-448958 https://reactome.org/PathwayBrowser/#/R-GGA-448958 Nuclear translocation of p38 MAPK IEA Gallus gallus A0A1D5NW33 R-GGA-5632652 https://reactome.org/PathwayBrowser/#/R-GGA-5632652 Hh-Npp binds CDON and PTCH IEA Gallus gallus A0A1D5NW43 R-GGA-917696 https://reactome.org/PathwayBrowser/#/R-GGA-917696 Cargo Sequestration IEA Gallus gallus A0A1D5NW43 R-GGA-917700 https://reactome.org/PathwayBrowser/#/R-GGA-917700 MVB Vesicle Formation IEA Gallus gallus A0A1D5NW61 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus A0A1D5NW61 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus A0A1D5NW63 R-GGA-202722 https://reactome.org/PathwayBrowser/#/R-GGA-202722 CD48 binds CD244 IEA Gallus gallus A0A1D5NW68 R-GGA-264679 https://reactome.org/PathwayBrowser/#/R-GGA-264679 Serum albumin binds 2-lysophosphatidylcholine IEA Gallus gallus A0A1D5NW68 R-GGA-481007 https://reactome.org/PathwayBrowser/#/R-GGA-481007 Exocytosis of platelet alpha granule contents IEA Gallus gallus A0A1D5NW68 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5NW68 R-GGA-9661419 https://reactome.org/PathwayBrowser/#/R-GGA-9661419 ALB binds extracellular heme IEA Gallus gallus A0A1D5NW68 R-GGA-9661425 https://reactome.org/PathwayBrowser/#/R-GGA-9661425 BIL:ALB dissociates IEA Gallus gallus A0A1D5NW68 R-GGA-9661432 https://reactome.org/PathwayBrowser/#/R-GGA-9661432 BIL binds ALB IEA Gallus gallus A0A1D5NW68 R-GGA-9709883 https://reactome.org/PathwayBrowser/#/R-GGA-9709883 BIL:ALB scavenges O2.- IEA Gallus gallus A0A1D5NW68 R-GGA-9733545 https://reactome.org/PathwayBrowser/#/R-GGA-9733545 Bile salts and acids bind ALB IEA Gallus gallus A0A1D5NW68 R-GGA-9733960 https://reactome.org/PathwayBrowser/#/R-GGA-9733960 Bile salts and acids dissociate from ALB IEA Gallus gallus A0A1D5NW68 R-GGA-9749590 https://reactome.org/PathwayBrowser/#/R-GGA-9749590 ASA- acetylates ALB IEA Gallus gallus A0A1D5NW68 R-GGA-9750666 https://reactome.org/PathwayBrowser/#/R-GGA-9750666 ALB binds ST IEA Gallus gallus A0A1D5NW68 R-GGA-9757574 https://reactome.org/PathwayBrowser/#/R-GGA-9757574 ALB binds PREDL IEA Gallus gallus A0A1D5NW68 R-GGA-9757578 https://reactome.org/PathwayBrowser/#/R-GGA-9757578 ALB binds PREDN IEA Gallus gallus A0A1D5NW68 R-GGA-9762343 https://reactome.org/PathwayBrowser/#/R-GGA-9762343 PREDL:ALB dissociates IEA Gallus gallus A0A1D5NW68 R-GGA-9762345 https://reactome.org/PathwayBrowser/#/R-GGA-9762345 PREDN:ALB dissociates IEA Gallus gallus A0A1D5NW68 R-GGA-9794444 https://reactome.org/PathwayBrowser/#/R-GGA-9794444 ALB binds Cipro IEA Gallus gallus A0A1D5NW68 R-GGA-9794475 https://reactome.org/PathwayBrowser/#/R-GGA-9794475 Cipro:ALB dissociates IEA Gallus gallus A0A1D5NW85 R-GGA-5229283 https://reactome.org/PathwayBrowser/#/R-GGA-5229283 LCNs bind lipids IEA Gallus gallus A0A1D5NWA7 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5NWA7 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5NWA7 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5NWA7 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5NWA9 R-GGA-9844006 https://reactome.org/PathwayBrowser/#/R-GGA-9844006 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) IEA Gallus gallus A0A1D5NWA9 R-GGA-9844015 https://reactome.org/PathwayBrowser/#/R-GGA-9844015 MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin IEA Gallus gallus A0A1D5NWA9 R-GGA-9844057 https://reactome.org/PathwayBrowser/#/R-GGA-9844057 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome IEA Gallus gallus A0A1D5NWC4 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5NWD0 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5NWD0 R-GGA-417858 https://reactome.org/PathwayBrowser/#/R-GGA-417858 P2Y14 receptor can bind to UDP-glucose IEA Gallus gallus A0A1D5NWD0 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5NWD0 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5NWE7 R-GGA-9854672 https://reactome.org/PathwayBrowser/#/R-GGA-9854672 FAD attaches to SDHA IEA Gallus gallus A0A1D5NWE8 R-GGA-109639 https://reactome.org/PathwayBrowser/#/R-GGA-109639 Formation of the closed pre-initiation complex IEA Gallus gallus A0A1D5NWE8 R-GGA-6810233 https://reactome.org/PathwayBrowser/#/R-GGA-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Gallus gallus A0A1D5NWE8 R-GGA-6810235 https://reactome.org/PathwayBrowser/#/R-GGA-6810235 RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain IEA Gallus gallus A0A1D5NWE8 R-GGA-6810238 https://reactome.org/PathwayBrowser/#/R-GGA-6810238 RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) IEA Gallus gallus A0A1D5NWE8 R-GGA-6814555 https://reactome.org/PathwayBrowser/#/R-GGA-6814555 Integrator complex processes the 3' end of snRNA IEA Gallus gallus A0A1D5NWE8 R-GGA-6814559 https://reactome.org/PathwayBrowser/#/R-GGA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Gallus gallus A0A1D5NWE8 R-GGA-73946 https://reactome.org/PathwayBrowser/#/R-GGA-73946 Abortive initiation after formation of the first phosphodiester bond IEA Gallus gallus A0A1D5NWE8 R-GGA-75095 https://reactome.org/PathwayBrowser/#/R-GGA-75095 Binding of TFIIE to the growing preinitiation complex IEA Gallus gallus A0A1D5NWE8 R-GGA-75850 https://reactome.org/PathwayBrowser/#/R-GGA-75850 Addition of the third nucleotide on the nascent transcript IEA Gallus gallus A0A1D5NWE8 R-GGA-75856 https://reactome.org/PathwayBrowser/#/R-GGA-75856 Abortive Initiation Before Second Transition IEA Gallus gallus A0A1D5NWE8 R-GGA-75861 https://reactome.org/PathwayBrowser/#/R-GGA-75861 NTP Binds Active Site of RNA Polymerase II IEA Gallus gallus A0A1D5NWE8 R-GGA-75862 https://reactome.org/PathwayBrowser/#/R-GGA-75862 Fall Back to Closed Pre-initiation Complex IEA Gallus gallus A0A1D5NWE8 R-GGA-75864 https://reactome.org/PathwayBrowser/#/R-GGA-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Gallus gallus A0A1D5NWE8 R-GGA-75866 https://reactome.org/PathwayBrowser/#/R-GGA-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Gallus gallus A0A1D5NWE8 R-GGA-75869 https://reactome.org/PathwayBrowser/#/R-GGA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Gallus gallus A0A1D5NWE8 R-GGA-75873 https://reactome.org/PathwayBrowser/#/R-GGA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Gallus gallus A0A1D5NWE8 R-GGA-75891 https://reactome.org/PathwayBrowser/#/R-GGA-75891 Abortive Initiation After Second Transition IEA Gallus gallus A0A1D5NWE8 R-GGA-75949 https://reactome.org/PathwayBrowser/#/R-GGA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Gallus gallus A0A1D5NWE8 R-GGA-9613494 https://reactome.org/PathwayBrowser/#/R-GGA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Gallus gallus A0A1D5NWE8 R-GGA-9613497 https://reactome.org/PathwayBrowser/#/R-GGA-9613497 Unwinding DNA for the nascent transcript IEA Gallus gallus A0A1D5NWG4 R-GGA-3108203 https://reactome.org/PathwayBrowser/#/R-GGA-3108203 PRC1 SUMOylates CTBP1 with SUMO2,3 IEA Gallus gallus A0A1D5NWG4 R-GGA-3108209 https://reactome.org/PathwayBrowser/#/R-GGA-3108209 PRC1 SUMOylates CTBP1 with SUMO1 IEA Gallus gallus A0A1D5NWG4 R-GGA-3229089 https://reactome.org/PathwayBrowser/#/R-GGA-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Gallus gallus A0A1D5NWG4 R-GGA-3229102 https://reactome.org/PathwayBrowser/#/R-GGA-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Gallus gallus A0A1D5NWG4 R-GGA-3927824 https://reactome.org/PathwayBrowser/#/R-GGA-3927824 PRC1 SUMOylates CASP8AP2 with SUMO1 IEA Gallus gallus A0A1D5NWG4 R-GGA-4551655 https://reactome.org/PathwayBrowser/#/R-GGA-4551655 CBX4 SUMOylates BMI1 in PRC1 with SUMO1 IEA Gallus gallus A0A1D5NWG4 R-GGA-4551727 https://reactome.org/PathwayBrowser/#/R-GGA-4551727 CBX4 SUMOylates CBX4 in PRC1 with SUMO1 IEA Gallus gallus A0A1D5NWG4 R-GGA-4570463 https://reactome.org/PathwayBrowser/#/R-GGA-4570463 CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 IEA Gallus gallus A0A1D5NWG4 R-GGA-4570499 https://reactome.org/PathwayBrowser/#/R-GGA-4570499 CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 IEA Gallus gallus A0A1D5NWG4 R-GGA-8937989 https://reactome.org/PathwayBrowser/#/R-GGA-8937989 RUNX1 binds PRC1 complexes IEA Gallus gallus A0A1D5NWG4 R-GGA-8943817 https://reactome.org/PathwayBrowser/#/R-GGA-8943817 MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter IEA Gallus gallus A0A1D5NWG7 R-GGA-1011598 https://reactome.org/PathwayBrowser/#/R-GGA-1011598 DOCKs bind to RhoGEFs IEA Gallus gallus A0A1D5NWG7 R-GGA-2029467 https://reactome.org/PathwayBrowser/#/R-GGA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Gallus gallus A0A1D5NWG7 R-GGA-2197697 https://reactome.org/PathwayBrowser/#/R-GGA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Gallus gallus A0A1D5NWG7 R-GGA-5218811 https://reactome.org/PathwayBrowser/#/R-GGA-5218811 DOCK180:ELMO binds CRK IEA Gallus gallus A0A1D5NWG7 R-GGA-5218839 https://reactome.org/PathwayBrowser/#/R-GGA-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Gallus gallus A0A1D5NWG7 R-GGA-8848611 https://reactome.org/PathwayBrowser/#/R-GGA-8848611 Phosphorylated PXN recruits the CRK complex IEA Gallus gallus A0A1D5NWG7 R-GGA-8848618 https://reactome.org/PathwayBrowser/#/R-GGA-8848618 Activation of RAC1 by the PXN:CRK complex IEA Gallus gallus A0A1D5NWG7 R-GGA-9013143 https://reactome.org/PathwayBrowser/#/R-GGA-9013143 RAC1 GEFs activate RAC1 IEA Gallus gallus A0A1D5NWG7 R-GGA-9014296 https://reactome.org/PathwayBrowser/#/R-GGA-9014296 RAC2 GEFs activate RAC2 IEA Gallus gallus A0A1D5NWG7 R-GGA-9014449 https://reactome.org/PathwayBrowser/#/R-GGA-9014449 RHOG binds effectors at the plasma membrane IEA Gallus gallus A0A1D5NWG9 R-GGA-372505 https://reactome.org/PathwayBrowser/#/R-GGA-372505 Acetylcholine synaptic vesicle docking and priming IEA Gallus gallus A0A1D5NWG9 R-GGA-374922 https://reactome.org/PathwayBrowser/#/R-GGA-374922 Noradrenalin synaptic vesicle docking and priming IEA Gallus gallus A0A1D5NWG9 R-GGA-449117 https://reactome.org/PathwayBrowser/#/R-GGA-449117 TXLNA (IL14) binds syntaxin1A IEA Gallus gallus A0A1D5NWG9 R-GGA-5682802 https://reactome.org/PathwayBrowser/#/R-GGA-5682802 LGI3 binds ADAM22,23,synatxin1 IEA Gallus gallus A0A1D5NWG9 R-GGA-9609921 https://reactome.org/PathwayBrowser/#/R-GGA-9609921 SGTA binds Tail-anchored protein IEA Gallus gallus A0A1D5NWH8 R-GGA-6806967 https://reactome.org/PathwayBrowser/#/R-GGA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Gallus gallus A0A1D5NWI2 R-GGA-174401 https://reactome.org/PathwayBrowser/#/R-GGA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Gallus gallus A0A1D5NWI3 R-GGA-8952618 https://reactome.org/PathwayBrowser/#/R-GGA-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NWI3 R-GGA-8952620 https://reactome.org/PathwayBrowser/#/R-GGA-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NWI3 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5NWI3 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5NWI3 R-GGA-8956200 https://reactome.org/PathwayBrowser/#/R-GGA-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NWI3 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5NWI3 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5NWI3 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5NWI3 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5NWK1 R-GGA-5667008 https://reactome.org/PathwayBrowser/#/R-GGA-5667008 RHOA:GTP binds RHPN1 or RHPN2 IEA Gallus gallus A0A1D5NWK1 R-GGA-9013009 https://reactome.org/PathwayBrowser/#/R-GGA-9013009 RHOA binds effectors at the plasma membrane IEA Gallus gallus A0A1D5NWK1 R-GGA-9690493 https://reactome.org/PathwayBrowser/#/R-GGA-9690493 RHOB binds effectors on endosomes IEA Gallus gallus A0A1D5NWK3 R-GGA-191299 https://reactome.org/PathwayBrowser/#/R-GGA-191299 Squalene is oxidized to its epoxide IEA Gallus gallus A0A1D5NWM4 R-GGA-1250189 https://reactome.org/PathwayBrowser/#/R-GGA-1250189 Binding of PI3K to ERBB2:p-ERBB3 heterodimer IEA Gallus gallus A0A1D5NWM4 R-GGA-1250195 https://reactome.org/PathwayBrowser/#/R-GGA-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Gallus gallus A0A1D5NWM4 R-GGA-1250346 https://reactome.org/PathwayBrowser/#/R-GGA-1250346 Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers IEA Gallus gallus A0A1D5NWM4 R-GGA-1250462 https://reactome.org/PathwayBrowser/#/R-GGA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Gallus gallus A0A1D5NWM4 R-GGA-1306957 https://reactome.org/PathwayBrowser/#/R-GGA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Gallus gallus A0A1D5NWM4 R-GGA-1306963 https://reactome.org/PathwayBrowser/#/R-GGA-1306963 Binding of GRB2:GAB1 to p-ERBB2:p-EGFR IEA Gallus gallus A0A1D5NWM4 R-GGA-1306965 https://reactome.org/PathwayBrowser/#/R-GGA-1306965 Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Gallus gallus A0A1D5NWM4 R-GGA-1306969 https://reactome.org/PathwayBrowser/#/R-GGA-1306969 GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers IEA Gallus gallus A0A1D5NWM4 R-GGA-1306972 https://reactome.org/PathwayBrowser/#/R-GGA-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Gallus gallus A0A1D5NWM4 R-GGA-1306979 https://reactome.org/PathwayBrowser/#/R-GGA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Gallus gallus A0A1D5NWM4 R-GGA-1358792 https://reactome.org/PathwayBrowser/#/R-GGA-1358792 RNF41 ubiquitinates activated ERBB3 IEA Gallus gallus A0A1D5NWM4 R-GGA-1358798 https://reactome.org/PathwayBrowser/#/R-GGA-1358798 RNF41 binds neuregulin-activated ERBB3 IEA Gallus gallus A0A1D5NWM4 R-GGA-1918092 https://reactome.org/PathwayBrowser/#/R-GGA-1918092 CHIP (STUB1) mediates ubiquitination of ERBB2 IEA Gallus gallus A0A1D5NWM4 R-GGA-1918095 https://reactome.org/PathwayBrowser/#/R-GGA-1918095 CUL5 mediates ubiquitination of ERBB2 IEA Gallus gallus A0A1D5NWM4 R-GGA-1963563 https://reactome.org/PathwayBrowser/#/R-GGA-1963563 MATK (CSK homologous kinase) binds phosphorylated ERBB2 IEA Gallus gallus A0A1D5NWM4 R-GGA-1963581 https://reactome.org/PathwayBrowser/#/R-GGA-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Gallus gallus A0A1D5NWM4 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus A0A1D5NWM4 R-GGA-1963586 https://reactome.org/PathwayBrowser/#/R-GGA-1963586 SRC family kinases phosphorylate ERBB2 IEA Gallus gallus A0A1D5NWM4 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5NWM4 R-GGA-373750 https://reactome.org/PathwayBrowser/#/R-GGA-373750 SEMA4D interacts with Plexin-B1:ErbB2 IEA Gallus gallus A0A1D5NWM4 R-GGA-416588 https://reactome.org/PathwayBrowser/#/R-GGA-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Gallus gallus A0A1D5NWM4 R-GGA-416594 https://reactome.org/PathwayBrowser/#/R-GGA-416594 LARG and PDZ-RhoGEF binds to Plexin-B1 IEA Gallus gallus A0A1D5NWM4 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5NWM4 R-GGA-6785636 https://reactome.org/PathwayBrowser/#/R-GGA-6785636 Phosphorylated ERBB2 heterodimers bind MEMO1 IEA Gallus gallus A0A1D5NWM4 R-GGA-8863804 https://reactome.org/PathwayBrowser/#/R-GGA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Gallus gallus A0A1D5NWM4 R-GGA-8864125 https://reactome.org/PathwayBrowser/#/R-GGA-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Gallus gallus A0A1D5NWM4 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus A0A1D5NWN1 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5NWN5 R-GGA-9667952 https://reactome.org/PathwayBrowser/#/R-GGA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Gallus gallus A0A1D5NWP1 R-GGA-1606273 https://reactome.org/PathwayBrowser/#/R-GGA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Gallus gallus A0A1D5NWP1 R-GGA-5626981 https://reactome.org/PathwayBrowser/#/R-GGA-5626981 TNF-α:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 IEA Gallus gallus A0A1D5NWP2 R-GGA-1168376 https://reactome.org/PathwayBrowser/#/R-GGA-1168376 STIM1 oligomerizes IEA Gallus gallus A0A1D5NWP2 R-GGA-2089927 https://reactome.org/PathwayBrowser/#/R-GGA-2089927 STIM1 binds TRPC1 forming STIM1:TRPC1 complex IEA Gallus gallus A0A1D5NWP2 R-GGA-2089943 https://reactome.org/PathwayBrowser/#/R-GGA-2089943 TRPC1 translocates calcium from the extracellular region to the cytosol IEA Gallus gallus A0A1D5NWP6 R-GGA-9933559 https://reactome.org/PathwayBrowser/#/R-GGA-9933559 The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1 IEA Gallus gallus A0A1D5NWP6 R-GGA-9933575 https://reactome.org/PathwayBrowser/#/R-GGA-9933575 MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome IEA Gallus gallus A0A1D5NWQ4 R-GGA-427656 https://reactome.org/PathwayBrowser/#/R-GGA-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Gallus gallus A0A1D5NWR6 R-GGA-5626938 https://reactome.org/PathwayBrowser/#/R-GGA-5626938 Beta-catenin binds SOX proteins IEA Gallus gallus A0A1D5NWR6 R-GGA-5665608 https://reactome.org/PathwayBrowser/#/R-GGA-5665608 TCF:Beta-catenin binds SOX proteins IEA Gallus gallus A0A1D5NWT1 R-GGA-189384 https://reactome.org/PathwayBrowser/#/R-GGA-189384 BLVRA:Zn2+, BLVRB reduce BV to BIL IEA Gallus gallus A0A1D5NWT2 R-GGA-9018787 https://reactome.org/PathwayBrowser/#/R-GGA-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Gallus gallus A0A1D5NWT4 R-GGA-198746 https://reactome.org/PathwayBrowser/#/R-GGA-198746 ERK1/2/5 activate RSK1/2/3 IEA Gallus gallus A0A1D5NWT4 R-GGA-199895 https://reactome.org/PathwayBrowser/#/R-GGA-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Gallus gallus A0A1D5NWT4 R-GGA-442724 https://reactome.org/PathwayBrowser/#/R-GGA-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Gallus gallus A0A1D5NWT4 R-GGA-9029434 https://reactome.org/PathwayBrowser/#/R-GGA-9029434 p-S363,S380,T573 RS6K translocates to the nucleus IEA Gallus gallus A0A1D5NWU3 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus A0A1D5NWU3 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus A0A1D5NWU3 R-GGA-8980691 https://reactome.org/PathwayBrowser/#/R-GGA-8980691 RHOA GEFs activate RHOA IEA Gallus gallus A0A1D5NWU3 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus A0A1D5NWU3 R-GGA-9013022 https://reactome.org/PathwayBrowser/#/R-GGA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Gallus gallus A0A1D5NWU3 R-GGA-9013111 https://reactome.org/PathwayBrowser/#/R-GGA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Gallus gallus A0A1D5NWU3 R-GGA-9013143 https://reactome.org/PathwayBrowser/#/R-GGA-9013143 RAC1 GEFs activate RAC1 IEA Gallus gallus A0A1D5NWU3 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus A0A1D5NWU3 R-GGA-9013159 https://reactome.org/PathwayBrowser/#/R-GGA-9013159 CDC42 GEFs activate CDC42 IEA Gallus gallus A0A1D5NWU3 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus A0A1D5NWU3 R-GGA-9014295 https://reactome.org/PathwayBrowser/#/R-GGA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Gallus gallus A0A1D5NWU3 R-GGA-9014296 https://reactome.org/PathwayBrowser/#/R-GGA-9014296 RAC2 GEFs activate RAC2 IEA Gallus gallus A0A1D5NWU3 R-GGA-9018806 https://reactome.org/PathwayBrowser/#/R-GGA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Gallus gallus A0A1D5NWW3 R-GGA-6781797 https://reactome.org/PathwayBrowser/#/R-GGA-6781797 USP19 binds HIF1A,BIRC2,BIRC3 IEA Gallus gallus A0A1D5NWW3 R-GGA-6781814 https://reactome.org/PathwayBrowser/#/R-GGA-6781814 USP19 deubiquitinates RNF123 IEA Gallus gallus A0A1D5NWX3 R-GGA-9717830 https://reactome.org/PathwayBrowser/#/R-GGA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Gallus gallus A0A1D5NWX3 R-GGA-9717834 https://reactome.org/PathwayBrowser/#/R-GGA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Gallus gallus A0A1D5NWX9 R-GGA-191636 https://reactome.org/PathwayBrowser/#/R-GGA-191636 Phosphorylation of Cx43 by c-src IEA Gallus gallus A0A1D5NWX9 R-GGA-191654 https://reactome.org/PathwayBrowser/#/R-GGA-191654 c-src associates with Cx43 in gap junctions IEA Gallus gallus A0A1D5NWX9 R-GGA-2064417 https://reactome.org/PathwayBrowser/#/R-GGA-2064417 WWTR1 (TAZ) binds ZO-1 (TJP1) IEA Gallus gallus A0A1D5NWX9 R-GGA-351913 https://reactome.org/PathwayBrowser/#/R-GGA-351913 Caspase-mediated cleavage of TJP1 IEA Gallus gallus A0A1D5NWY0 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5NWY9 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5NWZ3 R-GGA-6811431 https://reactome.org/PathwayBrowser/#/R-GGA-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Gallus gallus A0A1D5NWZ3 R-GGA-6814091 https://reactome.org/PathwayBrowser/#/R-GGA-6814091 ARL1 recruits TGN Golgin homodimers IEA Gallus gallus A0A1D5NWZ3 R-GGA-6814682 https://reactome.org/PathwayBrowser/#/R-GGA-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Gallus gallus A0A1D5NWZ6 R-GGA-9603775 https://reactome.org/PathwayBrowser/#/R-GGA-9603775 PEX3:PEX19:class I PMP dissociates IEA Gallus gallus A0A1D5NWZ6 R-GGA-9603784 https://reactome.org/PathwayBrowser/#/R-GGA-9603784 PEX19:class I PMP binds PEX3 IEA Gallus gallus A0A1D5NWZ6 R-GGA-9603804 https://reactome.org/PathwayBrowser/#/R-GGA-9603804 PEX19 binds class I peroxisomal membrane proteins IEA Gallus gallus A0A1D5NWZ8 R-GGA-109638 https://reactome.org/PathwayBrowser/#/R-GGA-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Gallus gallus A0A1D5NWZ8 R-GGA-109639 https://reactome.org/PathwayBrowser/#/R-GGA-109639 Formation of the closed pre-initiation complex IEA Gallus gallus A0A1D5NWZ8 R-GGA-111264 https://reactome.org/PathwayBrowser/#/R-GGA-111264 Addition of nucleotides between position +11 and +30 IEA Gallus gallus A0A1D5NWZ8 R-GGA-112381 https://reactome.org/PathwayBrowser/#/R-GGA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Gallus gallus A0A1D5NWZ8 R-GGA-112383 https://reactome.org/PathwayBrowser/#/R-GGA-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Gallus gallus A0A1D5NWZ8 R-GGA-112385 https://reactome.org/PathwayBrowser/#/R-GGA-112385 Addition of nucleotides leads to transcript elongation IEA Gallus gallus A0A1D5NWZ8 R-GGA-112392 https://reactome.org/PathwayBrowser/#/R-GGA-112392 Resumption of elongation after recovery from pausing IEA Gallus gallus A0A1D5NWZ8 R-GGA-112395 https://reactome.org/PathwayBrowser/#/R-GGA-112395 Abortive termination of elongation after arrest IEA Gallus gallus A0A1D5NWZ8 R-GGA-112396 https://reactome.org/PathwayBrowser/#/R-GGA-112396 Separation of elongating transcript from template IEA Gallus gallus A0A1D5NWZ8 R-GGA-113402 https://reactome.org/PathwayBrowser/#/R-GGA-113402 Formation of DSIF:NELF:early elongation complex IEA Gallus gallus A0A1D5NWZ8 R-GGA-113409 https://reactome.org/PathwayBrowser/#/R-GGA-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Gallus gallus A0A1D5NWZ8 R-GGA-113411 https://reactome.org/PathwayBrowser/#/R-GGA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Gallus gallus A0A1D5NWZ8 R-GGA-113412 https://reactome.org/PathwayBrowser/#/R-GGA-113412 Pol II elongation complex moves on the template as transcript elongates IEA Gallus gallus A0A1D5NWZ8 R-GGA-113413 https://reactome.org/PathwayBrowser/#/R-GGA-113413 TFIIS-mediated recovery of elongation from arrest IEA Gallus gallus A0A1D5NWZ8 R-GGA-113414 https://reactome.org/PathwayBrowser/#/R-GGA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Gallus gallus A0A1D5NWZ8 R-GGA-113430 https://reactome.org/PathwayBrowser/#/R-GGA-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Gallus gallus A0A1D5NWZ8 R-GGA-5578742 https://reactome.org/PathwayBrowser/#/R-GGA-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Gallus gallus A0A1D5NWZ8 R-GGA-6781818 https://reactome.org/PathwayBrowser/#/R-GGA-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Gallus gallus A0A1D5NWZ8 R-GGA-6781824 https://reactome.org/PathwayBrowser/#/R-GGA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Gallus gallus A0A1D5NWZ8 R-GGA-6781833 https://reactome.org/PathwayBrowser/#/R-GGA-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Gallus gallus A0A1D5NWZ8 R-GGA-6781840 https://reactome.org/PathwayBrowser/#/R-GGA-6781840 ERCC6 binds stalled RNA Pol II IEA Gallus gallus A0A1D5NWZ8 R-GGA-6781867 https://reactome.org/PathwayBrowser/#/R-GGA-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Gallus gallus A0A1D5NWZ8 R-GGA-6782069 https://reactome.org/PathwayBrowser/#/R-GGA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Gallus gallus A0A1D5NWZ8 R-GGA-6782131 https://reactome.org/PathwayBrowser/#/R-GGA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5NWZ8 R-GGA-6782138 https://reactome.org/PathwayBrowser/#/R-GGA-6782138 ERCC5 and RPA bind TC-NER site IEA Gallus gallus A0A1D5NWZ8 R-GGA-6782204 https://reactome.org/PathwayBrowser/#/R-GGA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Gallus gallus A0A1D5NWZ8 R-GGA-6782208 https://reactome.org/PathwayBrowser/#/R-GGA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Gallus gallus A0A1D5NWZ8 R-GGA-6782211 https://reactome.org/PathwayBrowser/#/R-GGA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Gallus gallus A0A1D5NWZ8 R-GGA-6782227 https://reactome.org/PathwayBrowser/#/R-GGA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Gallus gallus A0A1D5NWZ8 R-GGA-6797606 https://reactome.org/PathwayBrowser/#/R-GGA-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Gallus gallus A0A1D5NWZ8 R-GGA-6797616 https://reactome.org/PathwayBrowser/#/R-GGA-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Gallus gallus A0A1D5NWZ8 R-GGA-6803523 https://reactome.org/PathwayBrowser/#/R-GGA-6803523 PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA IEA Gallus gallus A0A1D5NWZ8 R-GGA-6810233 https://reactome.org/PathwayBrowser/#/R-GGA-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Gallus gallus A0A1D5NWZ8 R-GGA-6810235 https://reactome.org/PathwayBrowser/#/R-GGA-6810235 RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain IEA Gallus gallus A0A1D5NWZ8 R-GGA-6810238 https://reactome.org/PathwayBrowser/#/R-GGA-6810238 RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) IEA Gallus gallus A0A1D5NWZ8 R-GGA-6814555 https://reactome.org/PathwayBrowser/#/R-GGA-6814555 Integrator complex processes the 3' end of snRNA IEA Gallus gallus A0A1D5NWZ8 R-GGA-6814559 https://reactome.org/PathwayBrowser/#/R-GGA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Gallus gallus A0A1D5NWZ8 R-GGA-72095 https://reactome.org/PathwayBrowser/#/R-GGA-72095 Internal Methylation of mRNA IEA Gallus gallus A0A1D5NWZ8 R-GGA-72103 https://reactome.org/PathwayBrowser/#/R-GGA-72103 Formation of pre-mRNPs IEA Gallus gallus A0A1D5NWZ8 R-GGA-73946 https://reactome.org/PathwayBrowser/#/R-GGA-73946 Abortive initiation after formation of the first phosphodiester bond IEA Gallus gallus A0A1D5NWZ8 R-GGA-75079 https://reactome.org/PathwayBrowser/#/R-GGA-75079 Formation of AT-AC C complex IEA Gallus gallus A0A1D5NWZ8 R-GGA-75081 https://reactome.org/PathwayBrowser/#/R-GGA-75081 Formation of AT-AC B Complex IEA Gallus gallus A0A1D5NWZ8 R-GGA-75082 https://reactome.org/PathwayBrowser/#/R-GGA-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Gallus gallus A0A1D5NWZ8 R-GGA-75083 https://reactome.org/PathwayBrowser/#/R-GGA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Gallus gallus A0A1D5NWZ8 R-GGA-75095 https://reactome.org/PathwayBrowser/#/R-GGA-75095 Binding of TFIIE to the growing preinitiation complex IEA Gallus gallus A0A1D5NWZ8 R-GGA-75850 https://reactome.org/PathwayBrowser/#/R-GGA-75850 Addition of the third nucleotide on the nascent transcript IEA Gallus gallus A0A1D5NWZ8 R-GGA-75856 https://reactome.org/PathwayBrowser/#/R-GGA-75856 Abortive Initiation Before Second Transition IEA Gallus gallus A0A1D5NWZ8 R-GGA-75861 https://reactome.org/PathwayBrowser/#/R-GGA-75861 NTP Binds Active Site of RNA Polymerase II IEA Gallus gallus A0A1D5NWZ8 R-GGA-75862 https://reactome.org/PathwayBrowser/#/R-GGA-75862 Fall Back to Closed Pre-initiation Complex IEA Gallus gallus A0A1D5NWZ8 R-GGA-75864 https://reactome.org/PathwayBrowser/#/R-GGA-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Gallus gallus A0A1D5NWZ8 R-GGA-75866 https://reactome.org/PathwayBrowser/#/R-GGA-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Gallus gallus A0A1D5NWZ8 R-GGA-75869 https://reactome.org/PathwayBrowser/#/R-GGA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Gallus gallus A0A1D5NWZ8 R-GGA-75873 https://reactome.org/PathwayBrowser/#/R-GGA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Gallus gallus A0A1D5NWZ8 R-GGA-75891 https://reactome.org/PathwayBrowser/#/R-GGA-75891 Abortive Initiation After Second Transition IEA Gallus gallus A0A1D5NWZ8 R-GGA-75949 https://reactome.org/PathwayBrowser/#/R-GGA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Gallus gallus A0A1D5NWZ8 R-GGA-76576 https://reactome.org/PathwayBrowser/#/R-GGA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Gallus gallus A0A1D5NWZ8 R-GGA-77068 https://reactome.org/PathwayBrowser/#/R-GGA-77068 Activation of GT IEA Gallus gallus A0A1D5NWZ8 R-GGA-77069 https://reactome.org/PathwayBrowser/#/R-GGA-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Gallus gallus A0A1D5NWZ8 R-GGA-77071 https://reactome.org/PathwayBrowser/#/R-GGA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Gallus gallus A0A1D5NWZ8 R-GGA-77077 https://reactome.org/PathwayBrowser/#/R-GGA-77077 Capping complex formation IEA Gallus gallus A0A1D5NWZ8 R-GGA-77078 https://reactome.org/PathwayBrowser/#/R-GGA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Gallus gallus A0A1D5NWZ8 R-GGA-77081 https://reactome.org/PathwayBrowser/#/R-GGA-77081 Formation of the CE:GMP intermediate complex IEA Gallus gallus A0A1D5NWZ8 R-GGA-77083 https://reactome.org/PathwayBrowser/#/R-GGA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Gallus gallus A0A1D5NWZ8 R-GGA-77085 https://reactome.org/PathwayBrowser/#/R-GGA-77085 Dissociation of transcript with 5'-GMP from GT IEA Gallus gallus A0A1D5NWZ8 R-GGA-77095 https://reactome.org/PathwayBrowser/#/R-GGA-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Gallus gallus A0A1D5NWZ8 R-GGA-9012315 https://reactome.org/PathwayBrowser/#/R-GGA-9012315 ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene IEA Gallus gallus A0A1D5NWZ8 R-GGA-9012319 https://reactome.org/PathwayBrowser/#/R-GGA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Gallus gallus A0A1D5NWZ8 R-GGA-9613494 https://reactome.org/PathwayBrowser/#/R-GGA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Gallus gallus A0A1D5NWZ8 R-GGA-9613497 https://reactome.org/PathwayBrowser/#/R-GGA-9613497 Unwinding DNA for the nascent transcript IEA Gallus gallus A0A1D5NWZ8 R-GGA-9684118 https://reactome.org/PathwayBrowser/#/R-GGA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5NWZ8 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5NX03 R-GGA-8878664 https://reactome.org/PathwayBrowser/#/R-GGA-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Gallus gallus A0A1D5NX08 R-GGA-5693691 https://reactome.org/PathwayBrowser/#/R-GGA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Gallus gallus A0A1D5NX08 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus A0A1D5NX08 R-GGA-9727567 https://reactome.org/PathwayBrowser/#/R-GGA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Gallus gallus A0A1D5NX08 R-GGA-9749792 https://reactome.org/PathwayBrowser/#/R-GGA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Gallus gallus A0A1D5NX16 R-GGA-5173005 https://reactome.org/PathwayBrowser/#/R-GGA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Gallus gallus A0A1D5NX16 R-GGA-5173192 https://reactome.org/PathwayBrowser/#/R-GGA-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Gallus gallus A0A1D5NX31 R-GGA-1475022 https://reactome.org/PathwayBrowser/#/R-GGA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Gallus gallus A0A1D5NX31 R-GGA-1475026 https://reactome.org/PathwayBrowser/#/R-GGA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Gallus gallus A0A1D5NX31 R-GGA-1475435 https://reactome.org/PathwayBrowser/#/R-GGA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Gallus gallus A0A1D5NX31 R-GGA-1475436 https://reactome.org/PathwayBrowser/#/R-GGA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Gallus gallus A0A1D5NX31 R-GGA-9707419 https://reactome.org/PathwayBrowser/#/R-GGA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Gallus gallus A0A1D5NX54 R-GGA-187020 https://reactome.org/PathwayBrowser/#/R-GGA-187020 Part of pro-beta-NGF is processed to mature beta-NGF IEA Gallus gallus A0A1D5NX54 R-GGA-6784628 https://reactome.org/PathwayBrowser/#/R-GGA-6784628 PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Gallus gallus A0A1D5NX65 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1D5NX70 R-GGA-3247837 https://reactome.org/PathwayBrowser/#/R-GGA-3247837 WNT ligands traffic to the Golgi IEA Gallus gallus A0A1D5NX70 R-GGA-3247840 https://reactome.org/PathwayBrowser/#/R-GGA-3247840 WLS binds WNT ligands in the Golgi IEA Gallus gallus A0A1D5NX70 R-GGA-3247843 https://reactome.org/PathwayBrowser/#/R-GGA-3247843 secretion of WNT ligands IEA Gallus gallus A0A1D5NX70 R-GGA-3247844 https://reactome.org/PathwayBrowser/#/R-GGA-3247844 WNT ligands traffic to the plasma membrane IEA Gallus gallus A0A1D5NX70 R-GGA-3781941 https://reactome.org/PathwayBrowser/#/R-GGA-3781941 WNTs are secreted in exosomes IEA Gallus gallus A0A1D5NX70 R-GGA-3781943 https://reactome.org/PathwayBrowser/#/R-GGA-3781943 WLS:WNT complex is internalized for maturation into exosomes IEA Gallus gallus A0A1D5NX79 R-GGA-1250195 https://reactome.org/PathwayBrowser/#/R-GGA-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Gallus gallus A0A1D5NX79 R-GGA-1306957 https://reactome.org/PathwayBrowser/#/R-GGA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Gallus gallus A0A1D5NX79 R-GGA-1306963 https://reactome.org/PathwayBrowser/#/R-GGA-1306963 Binding of GRB2:GAB1 to p-ERBB2:p-EGFR IEA Gallus gallus A0A1D5NX79 R-GGA-1306965 https://reactome.org/PathwayBrowser/#/R-GGA-1306965 Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Gallus gallus A0A1D5NX79 R-GGA-177922 https://reactome.org/PathwayBrowser/#/R-GGA-177922 EGFR dimerization IEA Gallus gallus A0A1D5NX79 R-GGA-177923 https://reactome.org/PathwayBrowser/#/R-GGA-177923 Sustained activation of SRC kinase by SHP2 IEA Gallus gallus A0A1D5NX79 R-GGA-177924 https://reactome.org/PathwayBrowser/#/R-GGA-177924 Dephosphorylation of Gab1 by SHP2 IEA Gallus gallus A0A1D5NX79 R-GGA-177925 https://reactome.org/PathwayBrowser/#/R-GGA-177925 SHC1 binds to the phosphorylated EGF receptor:ligand complex IEA Gallus gallus A0A1D5NX79 R-GGA-177926 https://reactome.org/PathwayBrowser/#/R-GGA-177926 Dephosphorylation of PAG by SHP2 IEA Gallus gallus A0A1D5NX79 R-GGA-177927 https://reactome.org/PathwayBrowser/#/R-GGA-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 IEA Gallus gallus A0A1D5NX79 R-GGA-177930 https://reactome.org/PathwayBrowser/#/R-GGA-177930 GAB1 phosphorylation by EGFR kinase IEA Gallus gallus A0A1D5NX79 R-GGA-177933 https://reactome.org/PathwayBrowser/#/R-GGA-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Gallus gallus A0A1D5NX79 R-GGA-177934 https://reactome.org/PathwayBrowser/#/R-GGA-177934 EGFR autophosphorylation IEA Gallus gallus A0A1D5NX79 R-GGA-177935 https://reactome.org/PathwayBrowser/#/R-GGA-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Gallus gallus A0A1D5NX79 R-GGA-177936 https://reactome.org/PathwayBrowser/#/R-GGA-177936 GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR IEA Gallus gallus A0A1D5NX79 R-GGA-177937 https://reactome.org/PathwayBrowser/#/R-GGA-177937 Phosphorylation of EGFR by SRC kinase IEA Gallus gallus A0A1D5NX79 R-GGA-177938 https://reactome.org/PathwayBrowser/#/R-GGA-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Gallus gallus A0A1D5NX79 R-GGA-177939 https://reactome.org/PathwayBrowser/#/R-GGA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Gallus gallus A0A1D5NX79 R-GGA-177941 https://reactome.org/PathwayBrowser/#/R-GGA-177941 GRB2:GAB1 binds to phosphorylated EGFR IEA Gallus gallus A0A1D5NX79 R-GGA-177942 https://reactome.org/PathwayBrowser/#/R-GGA-177942 EGFR binds EGF ligand IEA Gallus gallus A0A1D5NX79 R-GGA-177943 https://reactome.org/PathwayBrowser/#/R-GGA-177943 GRB2:SOS1 complex binds to EGF:EGFR complex IEA Gallus gallus A0A1D5NX79 R-GGA-177944 https://reactome.org/PathwayBrowser/#/R-GGA-177944 Activation of SHP2 through the binding to phospho-Gab1 IEA Gallus gallus A0A1D5NX79 R-GGA-177945 https://reactome.org/PathwayBrowser/#/R-GGA-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Gallus gallus A0A1D5NX79 R-GGA-182969 https://reactome.org/PathwayBrowser/#/R-GGA-182969 Phosphorylation of CBL (EGFR:CBL) IEA Gallus gallus A0A1D5NX79 R-GGA-182986 https://reactome.org/PathwayBrowser/#/R-GGA-182986 CBL-mediated ubiquitination of CIN85 IEA Gallus gallus A0A1D5NX79 R-GGA-182990 https://reactome.org/PathwayBrowser/#/R-GGA-182990 Sprouty sequesters CBL away from active EGFR IEA Gallus gallus A0A1D5NX79 R-GGA-182993 https://reactome.org/PathwayBrowser/#/R-GGA-182993 Ubiquitination of stimulated EGFR (CBL) IEA Gallus gallus A0A1D5NX79 R-GGA-182994 https://reactome.org/PathwayBrowser/#/R-GGA-182994 Assembly of EGFR complex in clathrin-coated vesicles IEA Gallus gallus A0A1D5NX79 R-GGA-183002 https://reactome.org/PathwayBrowser/#/R-GGA-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Gallus gallus A0A1D5NX79 R-GGA-183036 https://reactome.org/PathwayBrowser/#/R-GGA-183036 Ubiquitination of stimulated EGFR (CBL:GRB2) IEA Gallus gallus A0A1D5NX79 R-GGA-183051 https://reactome.org/PathwayBrowser/#/R-GGA-183051 CBL ubiquitinates Sprouty IEA Gallus gallus A0A1D5NX79 R-GGA-183055 https://reactome.org/PathwayBrowser/#/R-GGA-183055 Binding of CBL to EGFR IEA Gallus gallus A0A1D5NX79 R-GGA-183058 https://reactome.org/PathwayBrowser/#/R-GGA-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Gallus gallus A0A1D5NX79 R-GGA-183067 https://reactome.org/PathwayBrowser/#/R-GGA-183067 Localization of CBL:GRB2 to the membrane IEA Gallus gallus A0A1D5NX79 R-GGA-183084 https://reactome.org/PathwayBrowser/#/R-GGA-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Gallus gallus A0A1D5NX79 R-GGA-183089 https://reactome.org/PathwayBrowser/#/R-GGA-183089 CBL binds and ubiquitinates phosphorylated Sprouty IEA Gallus gallus A0A1D5NX79 R-GGA-1963563 https://reactome.org/PathwayBrowser/#/R-GGA-1963563 MATK (CSK homologous kinase) binds phosphorylated ERBB2 IEA Gallus gallus A0A1D5NX79 R-GGA-1963581 https://reactome.org/PathwayBrowser/#/R-GGA-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Gallus gallus A0A1D5NX79 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus A0A1D5NX79 R-GGA-1963586 https://reactome.org/PathwayBrowser/#/R-GGA-1963586 SRC family kinases phosphorylate ERBB2 IEA Gallus gallus A0A1D5NX79 R-GGA-1977959 https://reactome.org/PathwayBrowser/#/R-GGA-1977959 ERBB4 forms heterodimers with EGFR IEA Gallus gallus A0A1D5NX79 R-GGA-212706 https://reactome.org/PathwayBrowser/#/R-GGA-212706 Phospholipase C-gamma1 binds to the activated EGF receptor IEA Gallus gallus A0A1D5NX79 R-GGA-212710 https://reactome.org/PathwayBrowser/#/R-GGA-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Gallus gallus A0A1D5NX79 R-GGA-212713 https://reactome.org/PathwayBrowser/#/R-GGA-212713 Active PLC-gamma1 dissociates from EGFR IEA Gallus gallus A0A1D5NX79 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5NX79 R-GGA-481007 https://reactome.org/PathwayBrowser/#/R-GGA-481007 Exocytosis of platelet alpha granule contents IEA Gallus gallus A0A1D5NX79 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5NX79 R-GGA-6785636 https://reactome.org/PathwayBrowser/#/R-GGA-6785636 Phosphorylated ERBB2 heterodimers bind MEMO1 IEA Gallus gallus A0A1D5NX79 R-GGA-8863804 https://reactome.org/PathwayBrowser/#/R-GGA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Gallus gallus A0A1D5NX79 R-GGA-8864029 https://reactome.org/PathwayBrowser/#/R-GGA-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Gallus gallus A0A1D5NX79 R-GGA-8864125 https://reactome.org/PathwayBrowser/#/R-GGA-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Gallus gallus A0A1D5NX79 R-GGA-8866279 https://reactome.org/PathwayBrowser/#/R-GGA-8866279 Epsin family proteins bind ubiquitinated cargo IEA Gallus gallus A0A1D5NX79 R-GGA-8867041 https://reactome.org/PathwayBrowser/#/R-GGA-8867041 EGFR phosphorylates EPS15 IEA Gallus gallus A0A1D5NX79 R-GGA-8867047 https://reactome.org/PathwayBrowser/#/R-GGA-8867047 PTPN3 dephosphorylates EPS15 IEA Gallus gallus A0A1D5NX79 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5NX79 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5NX79 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5NX79 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5NX79 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5NX79 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5NX79 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5NX79 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5NX79 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5NX79 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5NX79 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5NX79 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5NX79 R-GGA-8951490 https://reactome.org/PathwayBrowser/#/R-GGA-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Gallus gallus A0A1D5NX79 R-GGA-9018572 https://reactome.org/PathwayBrowser/#/R-GGA-9018572 EGFR phosphorylates NOTCH3 IEA Gallus gallus A0A1D5NX79 R-GGA-9018573 https://reactome.org/PathwayBrowser/#/R-GGA-9018573 NOTCH3 binds activated EGFR IEA Gallus gallus A0A1D5NX79 R-GGA-9625482 https://reactome.org/PathwayBrowser/#/R-GGA-9625482 PTK2 binds activated EGFR IEA Gallus gallus A0A1D5NX79 R-GGA-9625487 https://reactome.org/PathwayBrowser/#/R-GGA-9625487 PTK2 autophosphorylates downstream of EGFR IEA Gallus gallus A0A1D5NX80 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1D5NX80 R-GGA-9842833 https://reactome.org/PathwayBrowser/#/R-GGA-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Gallus gallus A0A1D5NX80 R-GGA-9842835 https://reactome.org/PathwayBrowser/#/R-GGA-9842835 KRAB-ZFP binds retroelement DNA in chromatin IEA Gallus gallus A0A1D5NX80 R-GGA-9842839 https://reactome.org/PathwayBrowser/#/R-GGA-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1D5NX80 R-GGA-9843978 https://reactome.org/PathwayBrowser/#/R-GGA-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1D5NX83 R-GGA-9932843 https://reactome.org/PathwayBrowser/#/R-GGA-9932843 PHF10 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD7 IEA Gallus gallus A0A1D5NX83 R-GGA-9933237 https://reactome.org/PathwayBrowser/#/R-GGA-9933237 PBRM1-containing ATPase complex binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD&:PHF10 IEA Gallus gallus A0A1D5NX83 R-GGA-9934021 https://reactome.org/PathwayBrowser/#/R-GGA-9934021 Formation of neuronal progenitor BAF (npBAF) IEA Gallus gallus A0A1D5NX83 R-GGA-9934022 https://reactome.org/PathwayBrowser/#/R-GGA-9934022 DPF2, PHF10 bind SMARCC1:SMARCC2 dimer:SMARD1:ARID1A IEA Gallus gallus A0A1D5NX83 R-GGA-9934024 https://reactome.org/PathwayBrowser/#/R-GGA-9934024 SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10 IEA Gallus gallus A0A1D5NXA6 R-GGA-481009 https://reactome.org/PathwayBrowser/#/R-GGA-481009 Exocytosis of platelet dense granule content IEA Gallus gallus A0A1D5NXA7 R-GGA-5689544 https://reactome.org/PathwayBrowser/#/R-GGA-5689544 UCHL5 binds INO80 complex IEA Gallus gallus A0A1D5NXA7 R-GGA-5691006 https://reactome.org/PathwayBrowser/#/R-GGA-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Gallus gallus A0A1D5NXB2 R-GGA-1504186 https://reactome.org/PathwayBrowser/#/R-GGA-1504186 DVL recruits GSK3beta:AXIN1 to the receptor complex IEA Gallus gallus A0A1D5NXB2 R-GGA-1504190 https://reactome.org/PathwayBrowser/#/R-GGA-1504190 DVL is ubiquitinated by CUL3:KLHL12:RBX1 IEA Gallus gallus A0A1D5NXB2 R-GGA-1504193 https://reactome.org/PathwayBrowser/#/R-GGA-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Gallus gallus A0A1D5NXB2 R-GGA-1504213 https://reactome.org/PathwayBrowser/#/R-GGA-1504213 DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex IEA Gallus gallus A0A1D5NXB2 R-GGA-201677 https://reactome.org/PathwayBrowser/#/R-GGA-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Gallus gallus A0A1D5NXB2 R-GGA-3772434 https://reactome.org/PathwayBrowser/#/R-GGA-3772434 Phosphorylated DVL recruits PIP5K1B to the plasma membrane IEA Gallus gallus A0A1D5NXB2 R-GGA-3772435 https://reactome.org/PathwayBrowser/#/R-GGA-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Gallus gallus A0A1D5NXB2 R-GGA-3772436 https://reactome.org/PathwayBrowser/#/R-GGA-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Gallus gallus A0A1D5NXB4 R-GGA-381518 https://reactome.org/PathwayBrowser/#/R-GGA-381518 PAAP-A proteolyzes IGF:IGFBP4 IEA Gallus gallus A0A1D5NXB9 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5NXB9 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5NXB9 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5NXB9 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5NXC4 R-GGA-75079 https://reactome.org/PathwayBrowser/#/R-GGA-75079 Formation of AT-AC C complex IEA Gallus gallus A0A1D5NXC4 R-GGA-75081 https://reactome.org/PathwayBrowser/#/R-GGA-75081 Formation of AT-AC B Complex IEA Gallus gallus A0A1D5NXC4 R-GGA-75082 https://reactome.org/PathwayBrowser/#/R-GGA-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Gallus gallus A0A1D5NXC4 R-GGA-75083 https://reactome.org/PathwayBrowser/#/R-GGA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Gallus gallus A0A1D5NXC7 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5NXC7 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5NXC7 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5NXC7 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5NXC9 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5NXC9 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5NXC9 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5NXC9 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5NXC9 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5NXC9 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus A0A1D5NXC9 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1D5NXC9 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5NXC9 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5NXC9 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5NXC9 R-GGA-8849350 https://reactome.org/PathwayBrowser/#/R-GGA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Gallus gallus A0A1D5NXC9 R-GGA-8849353 https://reactome.org/PathwayBrowser/#/R-GGA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Gallus gallus A0A1D5NXC9 R-GGA-9646679 https://reactome.org/PathwayBrowser/#/R-GGA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Gallus gallus A0A1D5NXC9 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1D5NXC9 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus A0A1D5NXD5 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5NXE7 R-GGA-1168642 https://reactome.org/PathwayBrowser/#/R-GGA-1168642 SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB IEA Gallus gallus A0A1D5NXE7 R-GGA-1168643 https://reactome.org/PathwayBrowser/#/R-GGA-1168643 SCF-beta-TrCP ubiquitinylates IkB IEA Gallus gallus A0A1D5NXE7 R-GGA-3000335 https://reactome.org/PathwayBrowser/#/R-GGA-3000335 SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA IEA Gallus gallus A0A1D5NXE7 R-GGA-3000339 https://reactome.org/PathwayBrowser/#/R-GGA-3000339 Phosphorylated BORA binds SCF-beta-TrCp1/2 IEA Gallus gallus A0A1D5NXE7 R-GGA-5607723 https://reactome.org/PathwayBrowser/#/R-GGA-5607723 SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB IEA Gallus gallus A0A1D5NXE7 R-GGA-5607728 https://reactome.org/PathwayBrowser/#/R-GGA-5607728 beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex IEA Gallus gallus A0A1D5NXE7 R-GGA-5684248 https://reactome.org/PathwayBrowser/#/R-GGA-5684248 SCF betaTrCP1,2 binds p-NFkB p105:TPL2:ABIN2 IEA Gallus gallus A0A1D5NXE7 R-GGA-5684250 https://reactome.org/PathwayBrowser/#/R-GGA-5684250 SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 IEA Gallus gallus A0A1D5NXE7 R-GGA-8952618 https://reactome.org/PathwayBrowser/#/R-GGA-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NXE7 R-GGA-8952620 https://reactome.org/PathwayBrowser/#/R-GGA-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NXE7 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5NXE7 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5NXE7 R-GGA-8956200 https://reactome.org/PathwayBrowser/#/R-GGA-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NXE7 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5NXE7 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5NXE7 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5NXE7 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5NXF5 R-GGA-4568863 https://reactome.org/PathwayBrowser/#/R-GGA-4568863 SUMOylation of RAD52 with SUMO1 IEA Gallus gallus A0A1D5NXF5 R-GGA-5686587 https://reactome.org/PathwayBrowser/#/R-GGA-5686587 ABL1 phosphorylates RAD52 IEA Gallus gallus A0A1D5NXF5 R-GGA-5686642 https://reactome.org/PathwayBrowser/#/R-GGA-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Gallus gallus A0A1D5NXF5 R-GGA-5687640 https://reactome.org/PathwayBrowser/#/R-GGA-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Gallus gallus A0A1D5NXF5 R-GGA-5693564 https://reactome.org/PathwayBrowser/#/R-GGA-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Gallus gallus A0A1D5NXF5 R-GGA-5693580 https://reactome.org/PathwayBrowser/#/R-GGA-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Gallus gallus A0A1D5NXF5 R-GGA-75998 https://reactome.org/PathwayBrowser/#/R-GGA-75998 Formation of RAD52 heptameric ring structure complexes IEA Gallus gallus A0A1D5NXH9 R-GGA-5682769 https://reactome.org/PathwayBrowser/#/R-GGA-5682769 LGI2 binds ADAM22,23 IEA Gallus gallus A0A1D5NXI7 R-GGA-5683964 https://reactome.org/PathwayBrowser/#/R-GGA-5683964 ATM phosphorylates EYA1-4 IEA Gallus gallus A0A1D5NXI7 R-GGA-5683967 https://reactome.org/PathwayBrowser/#/R-GGA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Gallus gallus A0A1D5NXJ2 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5NXJ2 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5NXJ2 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus A0A1D5NXJ7 R-GGA-420586 https://reactome.org/PathwayBrowser/#/R-GGA-420586 Necl-1:Necl-2 trans heterodimer interaction IEA Gallus gallus A0A1D5NXJ7 R-GGA-420592 https://reactome.org/PathwayBrowser/#/R-GGA-420592 Transhomodimerization of Nectin-like (Necl) proteins IEA Gallus gallus A0A1D5NXJ7 R-GGA-420595 https://reactome.org/PathwayBrowser/#/R-GGA-420595 Necl-2:Nectin 3 trans heterodimer interaction IEA Gallus gallus A0A1D5NXK5 R-GGA-1112666 https://reactome.org/PathwayBrowser/#/R-GGA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Gallus gallus A0A1D5NXK5 R-GGA-2197698 https://reactome.org/PathwayBrowser/#/R-GGA-2197698 Src phosphorylate WASP,N-WASP IEA Gallus gallus A0A1D5NXK5 R-GGA-2424476 https://reactome.org/PathwayBrowser/#/R-GGA-2424476 Activation of RAC1 by VAV2/3 IEA Gallus gallus A0A1D5NXK5 R-GGA-2424481 https://reactome.org/PathwayBrowser/#/R-GGA-2424481 Recruitment of VAV and BTK to p-SLP-76 IEA Gallus gallus A0A1D5NXK5 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus A0A1D5NXK5 R-GGA-2424485 https://reactome.org/PathwayBrowser/#/R-GGA-2424485 Release of p-PLCG1 IEA Gallus gallus A0A1D5NXK5 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus A0A1D5NXK5 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus A0A1D5NXK5 R-GGA-2730847 https://reactome.org/PathwayBrowser/#/R-GGA-2730847 Hydrolysis of PIP2 by PLCG IEA Gallus gallus A0A1D5NXK5 R-GGA-2730858 https://reactome.org/PathwayBrowser/#/R-GGA-2730858 Autophosphorylation of BTK/ITK IEA Gallus gallus A0A1D5NXK5 R-GGA-8964241 https://reactome.org/PathwayBrowser/#/R-GGA-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Gallus gallus A0A1D5NXK5 R-GGA-8964246 https://reactome.org/PathwayBrowser/#/R-GGA-8964246 BTK in G alpha (12)-BTK complex is activated IEA Gallus gallus A0A1D5NXK5 R-GGA-8964271 https://reactome.org/PathwayBrowser/#/R-GGA-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Gallus gallus A0A1D5NXK5 R-GGA-8964274 https://reactome.org/PathwayBrowser/#/R-GGA-8964274 G alpha (12) binds BTK IEA Gallus gallus A0A1D5NXK5 R-GGA-8964280 https://reactome.org/PathwayBrowser/#/R-GGA-8964280 Active Gq binds BTK IEA Gallus gallus A0A1D5NXK5 R-GGA-8964284 https://reactome.org/PathwayBrowser/#/R-GGA-8964284 BTK in active Gq-BTK complex is activated IEA Gallus gallus A0A1D5NXK5 R-GGA-8964317 https://reactome.org/PathwayBrowser/#/R-GGA-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Gallus gallus A0A1D5NXK5 R-GGA-8964333 https://reactome.org/PathwayBrowser/#/R-GGA-8964333 G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) IEA Gallus gallus A0A1D5NXK5 R-GGA-8964340 https://reactome.org/PathwayBrowser/#/R-GGA-8964340 Gq-BTK complex dissociates to Active BTK and Gq IEA Gallus gallus A0A1D5NXK5 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus A0A1D5NXL0 R-GGA-195418 https://reactome.org/PathwayBrowser/#/R-GGA-195418 NRP-2 associates with VEGFR1 forming complexes on cell surface IEA Gallus gallus A0A1D5NXL1 R-GGA-350058 https://reactome.org/PathwayBrowser/#/R-GGA-350058 Formation of CSL NCOR corepressor complex IEA Gallus gallus A0A1D5NXL1 R-GGA-3777129 https://reactome.org/PathwayBrowser/#/R-GGA-3777129 HDAC3 containing complexes deacetylate histone IEA Gallus gallus A0A1D5NXL1 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus A0A1D5NXL1 R-GGA-400183 https://reactome.org/PathwayBrowser/#/R-GGA-400183 PPARA:RXRA binds Corepressors of PPARA IEA Gallus gallus A0A1D5NXL1 R-GGA-9734475 https://reactome.org/PathwayBrowser/#/R-GGA-9734475 PPARA binds fibrates IEA Gallus gallus A0A1D5NXL1 R-GGA-9843115 https://reactome.org/PathwayBrowser/#/R-GGA-9843115 Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci IEA Gallus gallus A0A1D5NXL1 R-GGA-9843117 https://reactome.org/PathwayBrowser/#/R-GGA-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1D5NXL1 R-GGA-9843118 https://reactome.org/PathwayBrowser/#/R-GGA-9843118 RXRA binds ligands IEA Gallus gallus A0A1D5NXL4 R-GGA-6786205 https://reactome.org/PathwayBrowser/#/R-GGA-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 IEA Gallus gallus A0A1D5NXM5 R-GGA-2160851 https://reactome.org/PathwayBrowser/#/R-GGA-2160851 HAS1,2,3 mediate the polymerization of HA IEA Gallus gallus A0A1D5NXN5 R-GGA-8876616 https://reactome.org/PathwayBrowser/#/R-GGA-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Gallus gallus A0A1D5NXP2 R-GGA-482770 https://reactome.org/PathwayBrowser/#/R-GGA-482770 Release of platelet secretory granule components IEA Gallus gallus A0A1D5NXP2 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5NXP7 R-GGA-1369065 https://reactome.org/PathwayBrowser/#/R-GGA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Gallus gallus A0A1D5NXP9 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus A0A1D5NXP9 R-GGA-3928651 https://reactome.org/PathwayBrowser/#/R-GGA-3928651 NGEF exchanges GTP for GDP on RHOA IEA Gallus gallus A0A1D5NXP9 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus A0A1D5NXP9 R-GGA-8980691 https://reactome.org/PathwayBrowser/#/R-GGA-8980691 RHOA GEFs activate RHOA IEA Gallus gallus A0A1D5NXP9 R-GGA-9013143 https://reactome.org/PathwayBrowser/#/R-GGA-9013143 RAC1 GEFs activate RAC1 IEA Gallus gallus A0A1D5NXP9 R-GGA-9013159 https://reactome.org/PathwayBrowser/#/R-GGA-9013159 CDC42 GEFs activate CDC42 IEA Gallus gallus A0A1D5NXQ2 R-GGA-9008822 https://reactome.org/PathwayBrowser/#/R-GGA-9008822 PPM1D dephosphorylates RUNX2 IEA Gallus gallus A0A1D5NXQ4 R-GGA-2574840 https://reactome.org/PathwayBrowser/#/R-GGA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Gallus gallus A0A1D5NXQ4 R-GGA-2574845 https://reactome.org/PathwayBrowser/#/R-GGA-2574845 AJUBA binds centrosome-associated AURKA IEA Gallus gallus A0A1D5NXQ4 R-GGA-3000310 https://reactome.org/PathwayBrowser/#/R-GGA-3000310 AURKA phosphorylates PLK1 IEA Gallus gallus A0A1D5NXQ4 R-GGA-3000319 https://reactome.org/PathwayBrowser/#/R-GGA-3000319 BORA binds PLK1 and AURKA IEA Gallus gallus A0A1D5NXQ4 R-GGA-380272 https://reactome.org/PathwayBrowser/#/R-GGA-380272 Plk1-mediated phosphorylation of Nlp IEA Gallus gallus A0A1D5NXQ4 R-GGA-380283 https://reactome.org/PathwayBrowser/#/R-GGA-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Gallus gallus A0A1D5NXQ4 R-GGA-380294 https://reactome.org/PathwayBrowser/#/R-GGA-380294 Loss of C-Nap-1 from centrosomes IEA Gallus gallus A0A1D5NXQ4 R-GGA-380311 https://reactome.org/PathwayBrowser/#/R-GGA-380311 Recruitment of Plk1 to centrosomes IEA Gallus gallus A0A1D5NXQ4 R-GGA-380455 https://reactome.org/PathwayBrowser/#/R-GGA-380455 Recruitment of CDK11p58 to the centrosomes IEA Gallus gallus A0A1D5NXQ4 R-GGA-380508 https://reactome.org/PathwayBrowser/#/R-GGA-380508 Translocation of NuMA to the centrosomes IEA Gallus gallus A0A1D5NXQ4 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5NXQ4 R-GGA-5626228 https://reactome.org/PathwayBrowser/#/R-GGA-5626228 The distal appendage proteins recruit TTBK2 IEA Gallus gallus A0A1D5NXQ4 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1D5NXQ4 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1D5NXQ4 R-GGA-8853405 https://reactome.org/PathwayBrowser/#/R-GGA-8853405 TPX2 binds AURKA at centrosomes IEA Gallus gallus A0A1D5NXQ4 R-GGA-8853419 https://reactome.org/PathwayBrowser/#/R-GGA-8853419 TPX2 promotes AURKA autophosphorylation IEA Gallus gallus A0A1D5NXR2 R-GGA-351894 https://reactome.org/PathwayBrowser/#/R-GGA-351894 Caspase mediated cleavage of BAP31 IEA Gallus gallus A0A1D5NXR2 R-GGA-351948 https://reactome.org/PathwayBrowser/#/R-GGA-351948 Mitochondrial recruitment of Drp1 IEA Gallus gallus A0A1D5NXR2 R-GGA-8951499 https://reactome.org/PathwayBrowser/#/R-GGA-8951499 Loading of antigenic peptides on to class I MHC IEA Gallus gallus A0A1D5NXR2 R-GGA-9013004 https://reactome.org/PathwayBrowser/#/R-GGA-9013004 RHOA binds effectors at the ER membrane IEA Gallus gallus A0A1D5NXR2 R-GGA-983138 https://reactome.org/PathwayBrowser/#/R-GGA-983138 Transport of MHC heterotrimer to ER exit site IEA Gallus gallus A0A1D5NXR5 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1D5NXR5 R-GGA-9842833 https://reactome.org/PathwayBrowser/#/R-GGA-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Gallus gallus A0A1D5NXR5 R-GGA-9842835 https://reactome.org/PathwayBrowser/#/R-GGA-9842835 KRAB-ZFP binds retroelement DNA in chromatin IEA Gallus gallus A0A1D5NXR5 R-GGA-9842839 https://reactome.org/PathwayBrowser/#/R-GGA-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1D5NXR5 R-GGA-9843978 https://reactome.org/PathwayBrowser/#/R-GGA-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1D5NXS1 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1D5NXS1 R-GGA-388468 https://reactome.org/PathwayBrowser/#/R-GGA-388468 AVP(20-28) binds AVPR1A,B IEA Gallus gallus A0A1D5NXS1 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1D5NXS1 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1D5NXS1 R-GGA-9667456 https://reactome.org/PathwayBrowser/#/R-GGA-9667456 AVPR1A,B bind desmopressin IEA Gallus gallus A0A1D5NXS1 R-GGA-9667569 https://reactome.org/PathwayBrowser/#/R-GGA-9667569 AVPR1A,2 bind AVPR antagonists IEA Gallus gallus A0A1D5NXS1 R-GGA-9667619 https://reactome.org/PathwayBrowser/#/R-GGA-9667619 AVPR1A,B,2 bind atosiban IEA Gallus gallus A0A1D5NXT7 R-GGA-110218 https://reactome.org/PathwayBrowser/#/R-GGA-110218 Cleavage of uracil by TDG glycosylase IEA Gallus gallus A0A1D5NXT7 R-GGA-110219 https://reactome.org/PathwayBrowser/#/R-GGA-110219 Cleavage of thymine by TDG glycosylase IEA Gallus gallus A0A1D5NXT7 R-GGA-110234 https://reactome.org/PathwayBrowser/#/R-GGA-110234 Cleavage of ethenocytosine by TDG glycosylase IEA Gallus gallus A0A1D5NXT7 R-GGA-4551648 https://reactome.org/PathwayBrowser/#/R-GGA-4551648 SUMOylation of TDG with SUMO1 IEA Gallus gallus A0A1D5NXT7 R-GGA-4551738 https://reactome.org/PathwayBrowser/#/R-GGA-4551738 SUMOylation of TDG with SUMO2,3 IEA Gallus gallus A0A1D5NXT7 R-GGA-5220959 https://reactome.org/PathwayBrowser/#/R-GGA-5220959 TDG excises 5-formylcytosine IEA Gallus gallus A0A1D5NXT7 R-GGA-5221061 https://reactome.org/PathwayBrowser/#/R-GGA-5221061 TDG excises 5-carboxylcytosine IEA Gallus gallus A0A1D5NXU8 R-GGA-428518 https://reactome.org/PathwayBrowser/#/R-GGA-428518 Glypican-1 (GPC1) binds SLIT2 IEA Gallus gallus A0A1D5NXU8 R-GGA-9010815 https://reactome.org/PathwayBrowser/#/R-GGA-9010815 SLITs bind keratan sulfate IEA Gallus gallus A0A1D5NXU8 R-GGA-9010872 https://reactome.org/PathwayBrowser/#/R-GGA-9010872 SLIT2 binds Dystroglycan IEA Gallus gallus A0A1D5NXV1 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5NXV1 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5NXV1 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5NXV1 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5NXV1 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5NXV1 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus A0A1D5NXV1 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1D5NXV1 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5NXV1 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5NXV1 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5NXV1 R-GGA-8849350 https://reactome.org/PathwayBrowser/#/R-GGA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Gallus gallus A0A1D5NXV1 R-GGA-8849353 https://reactome.org/PathwayBrowser/#/R-GGA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Gallus gallus A0A1D5NXV1 R-GGA-9646679 https://reactome.org/PathwayBrowser/#/R-GGA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Gallus gallus A0A1D5NXV1 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1D5NXV1 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus A0A1D5NXW6 R-GGA-6783939 https://reactome.org/PathwayBrowser/#/R-GGA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus A0A1D5NXW6 R-GGA-70664 https://reactome.org/PathwayBrowser/#/R-GGA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus A0A1D5NXW7 R-GGA-1667005 https://reactome.org/PathwayBrowser/#/R-GGA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Gallus gallus A0A1D5NXW7 R-GGA-1678694 https://reactome.org/PathwayBrowser/#/R-GGA-1678694 Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans IEA Gallus gallus A0A1D5NXW7 R-GGA-1878002 https://reactome.org/PathwayBrowser/#/R-GGA-1878002 XYLTs transfer Xyl to core protein IEA Gallus gallus A0A1D5NXW7 R-GGA-1889955 https://reactome.org/PathwayBrowser/#/R-GGA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Gallus gallus A0A1D5NXW7 R-GGA-1889981 https://reactome.org/PathwayBrowser/#/R-GGA-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Gallus gallus A0A1D5NXW7 R-GGA-2022860 https://reactome.org/PathwayBrowser/#/R-GGA-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Gallus gallus A0A1D5NXW7 R-GGA-2022887 https://reactome.org/PathwayBrowser/#/R-GGA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Gallus gallus A0A1D5NXW7 R-GGA-2024084 https://reactome.org/PathwayBrowser/#/R-GGA-2024084 HS-GAGs translocate to the lysosome for degradation IEA Gallus gallus A0A1D5NXW7 R-GGA-2024108 https://reactome.org/PathwayBrowser/#/R-GGA-2024108 Some HSPGs are secreted to the plasma membrane IEA Gallus gallus A0A1D5NXW7 R-GGA-2076383 https://reactome.org/PathwayBrowser/#/R-GGA-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Gallus gallus A0A1D5NXW7 R-GGA-2076419 https://reactome.org/PathwayBrowser/#/R-GGA-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Gallus gallus A0A1D5NXW7 R-GGA-2076508 https://reactome.org/PathwayBrowser/#/R-GGA-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Gallus gallus A0A1D5NXW7 R-GGA-2076611 https://reactome.org/PathwayBrowser/#/R-GGA-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Gallus gallus A0A1D5NXW7 R-GGA-5362427 https://reactome.org/PathwayBrowser/#/R-GGA-5362427 Hh-Np binds GPC5 IEA Gallus gallus A0A1D5NXW7 R-GGA-5362553 https://reactome.org/PathwayBrowser/#/R-GGA-5362553 NOTUM releases Hh-Np:GPC5 from the plasma membrane IEA Gallus gallus A0A1D5NXY4 R-GGA-2995388 https://reactome.org/PathwayBrowser/#/R-GGA-2995388 PP2A dephosphorylates BANF1 IEA Gallus gallus A0A1D5NXZ3 R-GGA-8869241 https://reactome.org/PathwayBrowser/#/R-GGA-8869241 PITPNM1,2,3 exchange PI for PA IEA Gallus gallus A0A1D5NXZ7 R-GGA-425577 https://reactome.org/PathwayBrowser/#/R-GGA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Gallus gallus A0A1D5NY14 R-GGA-8876616 https://reactome.org/PathwayBrowser/#/R-GGA-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Gallus gallus A0A1D5NY23 R-GGA-6799777 https://reactome.org/PathwayBrowser/#/R-GGA-6799777 TP53 family members bind PPP1R13B or TP53BP2 IEA Gallus gallus A0A1D5NY28 R-GGA-5250930 https://reactome.org/PathwayBrowser/#/R-GGA-5250930 B-WICH recruits histone acetyltransferases IEA Gallus gallus A0A1D5NY28 R-GGA-5250938 https://reactome.org/PathwayBrowser/#/R-GGA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Gallus gallus A0A1D5NY28 R-GGA-5250947 https://reactome.org/PathwayBrowser/#/R-GGA-5250947 B-WICH complex binds rDNA promoter IEA Gallus gallus A0A1D5NY28 R-GGA-73757 https://reactome.org/PathwayBrowser/#/R-GGA-73757 Binding of RRN3 to RNA Polymerase I IEA Gallus gallus A0A1D5NY28 R-GGA-73758 https://reactome.org/PathwayBrowser/#/R-GGA-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Gallus gallus A0A1D5NY28 R-GGA-73769 https://reactome.org/PathwayBrowser/#/R-GGA-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Gallus gallus A0A1D5NY28 R-GGA-74986 https://reactome.org/PathwayBrowser/#/R-GGA-74986 Elongation of pre-rRNA transcript IEA Gallus gallus A0A1D5NY28 R-GGA-74993 https://reactome.org/PathwayBrowser/#/R-GGA-74993 PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box IEA Gallus gallus A0A1D5NY41 R-GGA-6799977 https://reactome.org/PathwayBrowser/#/R-GGA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Gallus gallus A0A1D5NY41 R-GGA-6799981 https://reactome.org/PathwayBrowser/#/R-GGA-6799981 PGLYRP2 binds bacterial peptidoglycan IEA Gallus gallus A0A1D5NY53 R-GGA-5652005 https://reactome.org/PathwayBrowser/#/R-GGA-5652005 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA IEA Gallus gallus A0A1D5NY53 R-GGA-5652009 https://reactome.org/PathwayBrowser/#/R-GGA-5652009 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA IEA Gallus gallus A0A1D5NY53 R-GGA-5653838 https://reactome.org/PathwayBrowser/#/R-GGA-5653838 POLD,POLE binds deISGylated PCNA after TLS IEA Gallus gallus A0A1D5NY53 R-GGA-5690213 https://reactome.org/PathwayBrowser/#/R-GGA-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Gallus gallus A0A1D5NY53 R-GGA-5693593 https://reactome.org/PathwayBrowser/#/R-GGA-5693593 D-loop extension by DNA polymerases IEA Gallus gallus A0A1D5NY53 R-GGA-6782211 https://reactome.org/PathwayBrowser/#/R-GGA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Gallus gallus A0A1D5NY53 R-GGA-68913 https://reactome.org/PathwayBrowser/#/R-GGA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Gallus gallus A0A1D5NY53 R-GGA-68914 https://reactome.org/PathwayBrowser/#/R-GGA-68914 DNA polymerase alpha:primase binds at the origin IEA Gallus gallus A0A1D5NY53 R-GGA-68960 https://reactome.org/PathwayBrowser/#/R-GGA-68960 DNA polymerase epsilon binds at the origin IEA Gallus gallus A0A1D5NY57 R-GGA-201712 https://reactome.org/PathwayBrowser/#/R-GGA-201712 Beta-catenin:TCF associates with BCL9 and PYGO IEA Gallus gallus A0A1D5NY57 R-GGA-3364026 https://reactome.org/PathwayBrowser/#/R-GGA-3364026 SET1 complex trimethylates H3K4 at the MYC gene IEA Gallus gallus A0A1D5NY63 R-GGA-5626938 https://reactome.org/PathwayBrowser/#/R-GGA-5626938 Beta-catenin binds SOX proteins IEA Gallus gallus A0A1D5NY70 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5NY78 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5NY78 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5NY78 R-GGA-2466068 https://reactome.org/PathwayBrowser/#/R-GGA-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Gallus gallus A0A1D5NY78 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5NY78 R-GGA-2468039 https://reactome.org/PathwayBrowser/#/R-GGA-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Gallus gallus A0A1D5NY78 R-GGA-2468040 https://reactome.org/PathwayBrowser/#/R-GGA-2468040 Cohesin binds PDS5 and WAPAL IEA Gallus gallus A0A1D5NY78 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5NY78 R-GGA-2468293 https://reactome.org/PathwayBrowser/#/R-GGA-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Gallus gallus A0A1D5NY78 R-GGA-2470935 https://reactome.org/PathwayBrowser/#/R-GGA-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Gallus gallus A0A1D5NY78 R-GGA-2473152 https://reactome.org/PathwayBrowser/#/R-GGA-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Gallus gallus A0A1D5NY78 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5NY78 R-GGA-2545203 https://reactome.org/PathwayBrowser/#/R-GGA-2545203 Deacetylation of cleaved cohesin IEA Gallus gallus A0A1D5NY78 R-GGA-2545253 https://reactome.org/PathwayBrowser/#/R-GGA-2545253 Deacetylation of cohesin IEA Gallus gallus A0A1D5NY78 R-GGA-3108212 https://reactome.org/PathwayBrowser/#/R-GGA-3108212 SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 IEA Gallus gallus A0A1D5NY79 R-GGA-8876454 https://reactome.org/PathwayBrowser/#/R-GGA-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Gallus gallus A0A1D5NY81 R-GGA-437136 https://reactome.org/PathwayBrowser/#/R-GGA-437136 SLC30A8 transports Zn2+ from cytosol to secretory granule IEA Gallus gallus A0A1D5NY81 R-GGA-437139 https://reactome.org/PathwayBrowser/#/R-GGA-437139 ZnT8 transports zinc into the Golgi apparatus IEA Gallus gallus A0A1D5NY86 R-GGA-1675813 https://reactome.org/PathwayBrowser/#/R-GGA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Gallus gallus A0A1D5NY86 R-GGA-1676185 https://reactome.org/PathwayBrowser/#/R-GGA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Gallus gallus A0A1D5NY95 R-GGA-425983 https://reactome.org/PathwayBrowser/#/R-GGA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Gallus gallus A0A1D5NY95 R-GGA-426015 https://reactome.org/PathwayBrowser/#/R-GGA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Gallus gallus A0A1D5NYA8 R-GGA-3371422 https://reactome.org/PathwayBrowser/#/R-GGA-3371422 ATP hydrolysis by HSP70 IEA Gallus gallus A0A1D5NYA8 R-GGA-3371503 https://reactome.org/PathwayBrowser/#/R-GGA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Gallus gallus A0A1D5NYA8 R-GGA-3371590 https://reactome.org/PathwayBrowser/#/R-GGA-3371590 HSP70 binds to HSP40:nascent protein IEA Gallus gallus A0A1D5NYB2 R-GGA-156808 https://reactome.org/PathwayBrowser/#/R-GGA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Gallus gallus A0A1D5NYB2 R-GGA-429955 https://reactome.org/PathwayBrowser/#/R-GGA-429955 CCR4-NOT complex deadenylates mRNA IEA Gallus gallus A0A1D5NYB2 R-GGA-429992 https://reactome.org/PathwayBrowser/#/R-GGA-429992 PARN deadenylates mRNA IEA Gallus gallus A0A1D5NYB2 R-GGA-430021 https://reactome.org/PathwayBrowser/#/R-GGA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Gallus gallus A0A1D5NYB2 R-GGA-450580 https://reactome.org/PathwayBrowser/#/R-GGA-450580 AUF1 (hnRNP D0) is ubiquitinylated IEA Gallus gallus A0A1D5NYB2 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1D5NYB2 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5NYB2 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5NYB5 R-GGA-2995388 https://reactome.org/PathwayBrowser/#/R-GGA-2995388 PP2A dephosphorylates BANF1 IEA Gallus gallus A0A1D5NYB5 R-GGA-2995389 https://reactome.org/PathwayBrowser/#/R-GGA-2995389 ANKLE2 binds VRK1,(VRK2) IEA Gallus gallus A0A1D5NYB5 R-GGA-9014467 https://reactome.org/PathwayBrowser/#/R-GGA-9014467 RHOG binds effectors at the ER membrane IEA Gallus gallus A0A1D5NYB5 R-GGA-9667952 https://reactome.org/PathwayBrowser/#/R-GGA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Gallus gallus A0A1D5NYD8 R-GGA-917693 https://reactome.org/PathwayBrowser/#/R-GGA-917693 ESCRT Disassembly IEA Gallus gallus A0A1D5NYD8 R-GGA-9668389 https://reactome.org/PathwayBrowser/#/R-GGA-9668389 VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations IEA Gallus gallus A0A1D5NYE7 R-GGA-8952044 https://reactome.org/PathwayBrowser/#/R-GGA-8952044 AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NYE7 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5NYE7 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5NYE7 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5NYE7 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5NYE7 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5NYE7 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5NYE8 R-GGA-195275 https://reactome.org/PathwayBrowser/#/R-GGA-195275 Phosphorylation of APC component of the destruction complex IEA Gallus gallus A0A1D5NYE8 R-GGA-195280 https://reactome.org/PathwayBrowser/#/R-GGA-195280 Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex IEA Gallus gallus A0A1D5NYE8 R-GGA-195283 https://reactome.org/PathwayBrowser/#/R-GGA-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Gallus gallus A0A1D5NYE8 R-GGA-195287 https://reactome.org/PathwayBrowser/#/R-GGA-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Gallus gallus A0A1D5NYE8 R-GGA-195300 https://reactome.org/PathwayBrowser/#/R-GGA-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Gallus gallus A0A1D5NYE8 R-GGA-195304 https://reactome.org/PathwayBrowser/#/R-GGA-195304 Association of beta-catenin with the destruction complex IEA Gallus gallus A0A1D5NYE8 R-GGA-195318 https://reactome.org/PathwayBrowser/#/R-GGA-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Gallus gallus A0A1D5NYE8 R-GGA-201669 https://reactome.org/PathwayBrowser/#/R-GGA-201669 Beta-catenin translocates to the nucleus IEA Gallus gallus A0A1D5NYE8 R-GGA-201712 https://reactome.org/PathwayBrowser/#/R-GGA-201712 Beta-catenin:TCF associates with BCL9 and PYGO IEA Gallus gallus A0A1D5NYE8 R-GGA-202969 https://reactome.org/PathwayBrowser/#/R-GGA-202969 Caspase mediated cleavage of beta-catenin IEA Gallus gallus A0A1D5NYE8 R-GGA-2130279 https://reactome.org/PathwayBrowser/#/R-GGA-2130279 Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex IEA Gallus gallus A0A1D5NYE8 R-GGA-2130282 https://reactome.org/PathwayBrowser/#/R-GGA-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Gallus gallus A0A1D5NYE8 R-GGA-2130286 https://reactome.org/PathwayBrowser/#/R-GGA-2130286 Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) IEA Gallus gallus A0A1D5NYE8 R-GGA-3134914 https://reactome.org/PathwayBrowser/#/R-GGA-3134914 Beta-catenin migrates to the nucleus IEA Gallus gallus A0A1D5NYE8 R-GGA-3299569 https://reactome.org/PathwayBrowser/#/R-GGA-3299569 Beta-catenin displaces TLE:HDAC1 from TCF/LEF IEA Gallus gallus A0A1D5NYE8 R-GGA-3322422 https://reactome.org/PathwayBrowser/#/R-GGA-3322422 Beta-catenin recruits SMARCA4 IEA Gallus gallus A0A1D5NYE8 R-GGA-3322424 https://reactome.org/PathwayBrowser/#/R-GGA-3322424 Beta-catenin recruits CDC73 and LEO1 IEA Gallus gallus A0A1D5NYE8 R-GGA-3322427 https://reactome.org/PathwayBrowser/#/R-GGA-3322427 Beta-catenin recruits CBP/p300 IEA Gallus gallus A0A1D5NYE8 R-GGA-3361751 https://reactome.org/PathwayBrowser/#/R-GGA-3361751 beta-catenin is replaced by repression complexes at the promoter IEA Gallus gallus A0A1D5NYE8 R-GGA-3364026 https://reactome.org/PathwayBrowser/#/R-GGA-3364026 SET1 complex trimethylates H3K4 at the MYC gene IEA Gallus gallus A0A1D5NYE8 R-GGA-3451153 https://reactome.org/PathwayBrowser/#/R-GGA-3451153 Beta-catenin recruits TRRAP/KAT5 HAT components IEA Gallus gallus A0A1D5NYE8 R-GGA-375140 https://reactome.org/PathwayBrowser/#/R-GGA-375140 CDO binds promyogenic cadherins IEA Gallus gallus A0A1D5NYE8 R-GGA-3769383 https://reactome.org/PathwayBrowser/#/R-GGA-3769383 CBY1 binds beta-catenin IEA Gallus gallus A0A1D5NYE8 R-GGA-3769391 https://reactome.org/PathwayBrowser/#/R-GGA-3769391 XPO1 binds the beta-catenin:CBY complex IEA Gallus gallus A0A1D5NYE8 R-GGA-3769392 https://reactome.org/PathwayBrowser/#/R-GGA-3769392 YWHAZ and XPO1 mediate the nuclear export of beta-catenin IEA Gallus gallus A0A1D5NYE8 R-GGA-3769393 https://reactome.org/PathwayBrowser/#/R-GGA-3769393 YWHAZ binds p-CBY:CTNNB1 IEA Gallus gallus A0A1D5NYE8 R-GGA-3769394 https://reactome.org/PathwayBrowser/#/R-GGA-3769394 AKT phosphorylates CBY1 IEA Gallus gallus A0A1D5NYE8 R-GGA-3772430 https://reactome.org/PathwayBrowser/#/R-GGA-3772430 CTNNBIP1 binds beta-catenin IEA Gallus gallus A0A1D5NYE8 R-GGA-419002 https://reactome.org/PathwayBrowser/#/R-GGA-419002 Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin IEA Gallus gallus A0A1D5NYE8 R-GGA-4411383 https://reactome.org/PathwayBrowser/#/R-GGA-4411383 NLK phosphorylates TCF/LEF IEA Gallus gallus A0A1D5NYE8 R-GGA-448958 https://reactome.org/PathwayBrowser/#/R-GGA-448958 Nuclear translocation of p38 MAPK IEA Gallus gallus A0A1D5NYE8 R-GGA-5357477 https://reactome.org/PathwayBrowser/#/R-GGA-5357477 PAK1-3 phosphorylates VE-cadherin IEA Gallus gallus A0A1D5NYE8 R-GGA-5626938 https://reactome.org/PathwayBrowser/#/R-GGA-5626938 Beta-catenin binds SOX proteins IEA Gallus gallus A0A1D5NYE8 R-GGA-5665608 https://reactome.org/PathwayBrowser/#/R-GGA-5665608 TCF:Beta-catenin binds SOX proteins IEA Gallus gallus A0A1D5NYE8 R-GGA-8951428 https://reactome.org/PathwayBrowser/#/R-GGA-8951428 RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) IEA Gallus gallus A0A1D5NYE8 R-GGA-9761421 https://reactome.org/PathwayBrowser/#/R-GGA-9761421 CDH11 associates with catenins IEA Gallus gallus A0A1D5NYE8 R-GGA-9761474 https://reactome.org/PathwayBrowser/#/R-GGA-9761474 AMOT-2 binds CDH11 IEA Gallus gallus A0A1D5NYE8 R-GGA-9762246 https://reactome.org/PathwayBrowser/#/R-GGA-9762246 ANGPTL4 binds CDH11 IEA Gallus gallus A0A1D5NYE8 R-GGA-9762282 https://reactome.org/PathwayBrowser/#/R-GGA-9762282 CTNNB1 dissociates from CDH11 upon ANGPTL4 binding IEA Gallus gallus A0A1D5NYE8 R-GGA-9858647 https://reactome.org/PathwayBrowser/#/R-GGA-9858647 HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter IEA Gallus gallus A0A1D5NYF3 R-GGA-5334794 https://reactome.org/PathwayBrowser/#/R-GGA-5334794 FABPs bind LCFAs IEA Gallus gallus A0A1D5NYI2 R-GGA-5688289 https://reactome.org/PathwayBrowser/#/R-GGA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Gallus gallus A0A1D5NYI2 R-GGA-9620532 https://reactome.org/PathwayBrowser/#/R-GGA-9620532 SIRT1,SIRT3 deacetylate FOXO3 IEA Gallus gallus A0A1D5NYI2 R-GGA-9841847 https://reactome.org/PathwayBrowser/#/R-GGA-9841847 SIRT3 deacetylates Ac-K272,K290-FOXO3 IEA Gallus gallus A0A1D5NYI2 R-GGA-9854463 https://reactome.org/PathwayBrowser/#/R-GGA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Gallus gallus A0A1D5NYI5 R-GGA-1918095 https://reactome.org/PathwayBrowser/#/R-GGA-1918095 CUL5 mediates ubiquitination of ERBB2 IEA Gallus gallus A0A1D5NYI5 R-GGA-8952044 https://reactome.org/PathwayBrowser/#/R-GGA-8952044 AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NYI5 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5NYI5 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5NYI5 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5NYI5 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5NYI5 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5NYI5 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5NYJ2 R-GGA-9837978 https://reactome.org/PathwayBrowser/#/R-GGA-9837978 LONP1 binds mitochondrial inner membrane proteins IEA Gallus gallus A0A1D5NYJ2 R-GGA-9838004 https://reactome.org/PathwayBrowser/#/R-GGA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Gallus gallus A0A1D5NYJ2 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1D5NYJ2 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1D5NYL1 R-GGA-1237038 https://reactome.org/PathwayBrowser/#/R-GGA-1237038 SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- IEA Gallus gallus A0A1D5NYL1 R-GGA-1247665 https://reactome.org/PathwayBrowser/#/R-GGA-1247665 SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- IEA Gallus gallus A0A1D5NYL1 R-GGA-425482 https://reactome.org/PathwayBrowser/#/R-GGA-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Gallus gallus A0A1D5NYL4 R-GGA-448955 https://reactome.org/PathwayBrowser/#/R-GGA-448955 Phosphorylation of MEF2 proteins by p38 IEA Gallus gallus A0A1D5NYL4 R-GGA-448963 https://reactome.org/PathwayBrowser/#/R-GGA-448963 Interaction of MyoD:E protein with MEF2 IEA Gallus gallus A0A1D5NYL7 R-GGA-1296037 https://reactome.org/PathwayBrowser/#/R-GGA-1296037 Activation of Ca2+ activated Potassium channels with large conductance IEA Gallus gallus A0A1D5NYL8 R-GGA-8956568 https://reactome.org/PathwayBrowser/#/R-GGA-8956568 RUNX1 binds the core TAL1 complex IEA Gallus gallus A0A1D5NYM4 R-GGA-212007 https://reactome.org/PathwayBrowser/#/R-GGA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Gallus gallus A0A1D5NYM4 R-GGA-5362525 https://reactome.org/PathwayBrowser/#/R-GGA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Gallus gallus A0A1D5NYP5 R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus A0A1D5NYP5 R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus A0A1D5NYP5 R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus A0A1D5NYP8 R-GGA-1250195 https://reactome.org/PathwayBrowser/#/R-GGA-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Gallus gallus A0A1D5NYP8 R-GGA-1250348 https://reactome.org/PathwayBrowser/#/R-GGA-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Gallus gallus A0A1D5NYP8 R-GGA-1250357 https://reactome.org/PathwayBrowser/#/R-GGA-1250357 SHC1 binds P-ERBB4 isoform dimers IEA Gallus gallus A0A1D5NYP8 R-GGA-1250380 https://reactome.org/PathwayBrowser/#/R-GGA-1250380 Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers IEA Gallus gallus A0A1D5NYP8 R-GGA-1250383 https://reactome.org/PathwayBrowser/#/R-GGA-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Gallus gallus A0A1D5NYP8 R-GGA-177925 https://reactome.org/PathwayBrowser/#/R-GGA-177925 SHC1 binds to the phosphorylated EGF receptor:ligand complex IEA Gallus gallus A0A1D5NYP8 R-GGA-177933 https://reactome.org/PathwayBrowser/#/R-GGA-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Gallus gallus A0A1D5NYP8 R-GGA-177936 https://reactome.org/PathwayBrowser/#/R-GGA-177936 GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR IEA Gallus gallus A0A1D5NYP8 R-GGA-177945 https://reactome.org/PathwayBrowser/#/R-GGA-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Gallus gallus A0A1D5NYP8 R-GGA-204861 https://reactome.org/PathwayBrowser/#/R-GGA-204861 Interaction of Tie2 and Shc1 IEA Gallus gallus A0A1D5NYP8 R-GGA-2396561 https://reactome.org/PathwayBrowser/#/R-GGA-2396561 Recruitment of GADS:SLP-76 to p-5Y-LAT IEA Gallus gallus A0A1D5NYP8 R-GGA-2396594 https://reactome.org/PathwayBrowser/#/R-GGA-2396594 Phosphorylation of SLP-76 by p-SYK IEA Gallus gallus A0A1D5NYP8 R-GGA-2396606 https://reactome.org/PathwayBrowser/#/R-GGA-2396606 Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT IEA Gallus gallus A0A1D5NYP8 R-GGA-2404193 https://reactome.org/PathwayBrowser/#/R-GGA-2404193 IGF1R phosphorylates SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-2404195 https://reactome.org/PathwayBrowser/#/R-GGA-2404195 IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-2424476 https://reactome.org/PathwayBrowser/#/R-GGA-2424476 Activation of RAC1 by VAV2/3 IEA Gallus gallus A0A1D5NYP8 R-GGA-2424477 https://reactome.org/PathwayBrowser/#/R-GGA-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Gallus gallus A0A1D5NYP8 R-GGA-2424481 https://reactome.org/PathwayBrowser/#/R-GGA-2424481 Recruitment of VAV and BTK to p-SLP-76 IEA Gallus gallus A0A1D5NYP8 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus A0A1D5NYP8 R-GGA-2424485 https://reactome.org/PathwayBrowser/#/R-GGA-2424485 Release of p-PLCG1 IEA Gallus gallus A0A1D5NYP8 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus A0A1D5NYP8 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus A0A1D5NYP8 R-GGA-2730837 https://reactome.org/PathwayBrowser/#/R-GGA-2730837 Recruitment of GRB2:SOS to p-10Y-NTAL IEA Gallus gallus A0A1D5NYP8 R-GGA-2730840 https://reactome.org/PathwayBrowser/#/R-GGA-2730840 Activation of RAC1 by VAV IEA Gallus gallus A0A1D5NYP8 R-GGA-2730841 https://reactome.org/PathwayBrowser/#/R-GGA-2730841 Phosphorylation and activation of VAV IEA Gallus gallus A0A1D5NYP8 R-GGA-2730842 https://reactome.org/PathwayBrowser/#/R-GGA-2730842 PI3K associates with phosphorylated GAB2 IEA Gallus gallus A0A1D5NYP8 R-GGA-2730844 https://reactome.org/PathwayBrowser/#/R-GGA-2730844 Interaction of GRB2:SOS complex with p-SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-2730847 https://reactome.org/PathwayBrowser/#/R-GGA-2730847 Hydrolysis of PIP2 by PLCG IEA Gallus gallus A0A1D5NYP8 R-GGA-2730856 https://reactome.org/PathwayBrowser/#/R-GGA-2730856 Autophosphorylation of PAK IEA Gallus gallus A0A1D5NYP8 R-GGA-2730858 https://reactome.org/PathwayBrowser/#/R-GGA-2730858 Autophosphorylation of BTK/ITK IEA Gallus gallus A0A1D5NYP8 R-GGA-2730870 https://reactome.org/PathwayBrowser/#/R-GGA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Gallus gallus A0A1D5NYP8 R-GGA-2730889 https://reactome.org/PathwayBrowser/#/R-GGA-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-2730892 https://reactome.org/PathwayBrowser/#/R-GGA-2730892 Recruitment of VAV to p-SLP-76 IEA Gallus gallus A0A1D5NYP8 R-GGA-432096 https://reactome.org/PathwayBrowser/#/R-GGA-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-443905 https://reactome.org/PathwayBrowser/#/R-GGA-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Gallus gallus A0A1D5NYP8 R-GGA-443910 https://reactome.org/PathwayBrowser/#/R-GGA-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Gallus gallus A0A1D5NYP8 R-GGA-453104 https://reactome.org/PathwayBrowser/#/R-GGA-453104 Phosphorylated SHC1 recruits GRB2:GAB2 IEA Gallus gallus A0A1D5NYP8 R-GGA-453111 https://reactome.org/PathwayBrowser/#/R-GGA-453111 Phosphorylated SHC recruits GRB2:SOS1 IEA Gallus gallus A0A1D5NYP8 R-GGA-508247 https://reactome.org/PathwayBrowser/#/R-GGA-508247 Gab2 binds the p85 subunit of Class 1A PI3 kinases IEA Gallus gallus A0A1D5NYP8 R-GGA-5654402 https://reactome.org/PathwayBrowser/#/R-GGA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5NYP8 R-GGA-5654404 https://reactome.org/PathwayBrowser/#/R-GGA-5654404 Activated FGFR2 binds SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-5654406 https://reactome.org/PathwayBrowser/#/R-GGA-5654406 Activated FGFR2:p-SHC1 binds GRB2:SOS1 IEA Gallus gallus A0A1D5NYP8 R-GGA-5654407 https://reactome.org/PathwayBrowser/#/R-GGA-5654407 Activated FGFR2 phosphorylates SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-5654423 https://reactome.org/PathwayBrowser/#/R-GGA-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Gallus gallus A0A1D5NYP8 R-GGA-5654425 https://reactome.org/PathwayBrowser/#/R-GGA-5654425 Activated FGFR4 binds SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-5654426 https://reactome.org/PathwayBrowser/#/R-GGA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5NYP8 R-GGA-5654428 https://reactome.org/PathwayBrowser/#/R-GGA-5654428 Activated FGFR4 phosphorylates SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-5654573 https://reactome.org/PathwayBrowser/#/R-GGA-5654573 Activated FGFR1 binds SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-5654582 https://reactome.org/PathwayBrowser/#/R-GGA-5654582 Activated FGFR1 phosphorylates SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-5654597 https://reactome.org/PathwayBrowser/#/R-GGA-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Gallus gallus A0A1D5NYP8 R-GGA-5654600 https://reactome.org/PathwayBrowser/#/R-GGA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5NYP8 R-GGA-5654625 https://reactome.org/PathwayBrowser/#/R-GGA-5654625 Activated FGFR3 binds SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-5654634 https://reactome.org/PathwayBrowser/#/R-GGA-5654634 Activated FGFR3 phosphorylates SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-5654646 https://reactome.org/PathwayBrowser/#/R-GGA-5654646 Activated FGFR3:p-SHC1 binds GRB2:SOS1 IEA Gallus gallus A0A1D5NYP8 R-GGA-5654647 https://reactome.org/PathwayBrowser/#/R-GGA-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5NYP8 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5NYP8 R-GGA-5685366 https://reactome.org/PathwayBrowser/#/R-GGA-5685366 GRB2-1:SOS1 binds p-Y-SHC IEA Gallus gallus A0A1D5NYP8 R-GGA-5686072 https://reactome.org/PathwayBrowser/#/R-GGA-5686072 p-3Y-SHC1 dissociates from IGF1R IEA Gallus gallus A0A1D5NYP8 R-GGA-5686073 https://reactome.org/PathwayBrowser/#/R-GGA-5686073 GRB2-1:SOS1 binds p-3Y-SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-5686074 https://reactome.org/PathwayBrowser/#/R-GGA-5686074 GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates IEA Gallus gallus A0A1D5NYP8 R-GGA-74740 https://reactome.org/PathwayBrowser/#/R-GGA-74740 Binding of SHC1 to insulin receptor IEA Gallus gallus A0A1D5NYP8 R-GGA-74742 https://reactome.org/PathwayBrowser/#/R-GGA-74742 Phosphorylation of SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-74743 https://reactome.org/PathwayBrowser/#/R-GGA-74743 Dissociation of p-Y427-SHC1 from insulin receptor IEA Gallus gallus A0A1D5NYP8 R-GGA-74746 https://reactome.org/PathwayBrowser/#/R-GGA-74746 GRB2-1:SOS1 binds p-Y427-SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-879934 https://reactome.org/PathwayBrowser/#/R-GGA-879934 Recruitment of SHC1 is mediated by Y593 of the common beta chain IEA Gallus gallus A0A1D5NYP8 R-GGA-8851888 https://reactome.org/PathwayBrowser/#/R-GGA-8851888 MET binds SHC1-2 IEA Gallus gallus A0A1D5NYP8 R-GGA-8851890 https://reactome.org/PathwayBrowser/#/R-GGA-8851890 MET phosphorylates SHC1-2 IEA Gallus gallus A0A1D5NYP8 R-GGA-8851899 https://reactome.org/PathwayBrowser/#/R-GGA-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Gallus gallus A0A1D5NYP8 R-GGA-8851900 https://reactome.org/PathwayBrowser/#/R-GGA-8851900 SHC1-2 bound to MET recruits GRB2:SOS1 IEA Gallus gallus A0A1D5NYP8 R-GGA-8853734 https://reactome.org/PathwayBrowser/#/R-GGA-8853734 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 IEA Gallus gallus A0A1D5NYP8 R-GGA-8853737 https://reactome.org/PathwayBrowser/#/R-GGA-8853737 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-8853774 https://reactome.org/PathwayBrowser/#/R-GGA-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Gallus gallus A0A1D5NYP8 R-GGA-8853793 https://reactome.org/PathwayBrowser/#/R-GGA-8853793 p-5Y-RET complexes bind GRB2 IEA Gallus gallus A0A1D5NYP8 R-GGA-8854897 https://reactome.org/PathwayBrowser/#/R-GGA-8854897 p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2 IEA Gallus gallus A0A1D5NYP8 R-GGA-8854905 https://reactome.org/PathwayBrowser/#/R-GGA-8854905 p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K IEA Gallus gallus A0A1D5NYP8 R-GGA-8854981 https://reactome.org/PathwayBrowser/#/R-GGA-8854981 SHC1 in the RET complex is phosphorylated IEA Gallus gallus A0A1D5NYP8 R-GGA-8855508 https://reactome.org/PathwayBrowser/#/R-GGA-8855508 p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 IEA Gallus gallus A0A1D5NYP8 R-GGA-8934446 https://reactome.org/PathwayBrowser/#/R-GGA-8934446 Activated PKC phosphorylates SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-8934465 https://reactome.org/PathwayBrowser/#/R-GGA-8934465 SHC1 binds PTPN12 IEA Gallus gallus A0A1D5NYP8 R-GGA-8983384 https://reactome.org/PathwayBrowser/#/R-GGA-8983384 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 IEA Gallus gallus A0A1D5NYP8 R-GGA-912527 https://reactome.org/PathwayBrowser/#/R-GGA-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Gallus gallus A0A1D5NYP8 R-GGA-913374 https://reactome.org/PathwayBrowser/#/R-GGA-913374 Phosphorylated SHC1 recruits SHIP IEA Gallus gallus A0A1D5NYP8 R-GGA-913424 https://reactome.org/PathwayBrowser/#/R-GGA-913424 The SHC1:SHIP1 complex is stabilized by GRB2 IEA Gallus gallus A0A1D5NYP8 R-GGA-9624272 https://reactome.org/PathwayBrowser/#/R-GGA-9624272 MMPs cleave HB-EGF IEA Gallus gallus A0A1D5NYP8 R-GGA-9634584 https://reactome.org/PathwayBrowser/#/R-GGA-9634584 Estrogen receptor binds IGF1R and SHC1 in response to estrogen IEA Gallus gallus A0A1D5NYP8 R-GGA-9674816 https://reactome.org/PathwayBrowser/#/R-GGA-9674816 p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS IEA Gallus gallus A0A1D5NYP8 R-GGA-9700154 https://reactome.org/PathwayBrowser/#/R-GGA-9700154 Active ALK binds SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-9700175 https://reactome.org/PathwayBrowser/#/R-GGA-9700175 Active ALK phosphorylates SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-9842641 https://reactome.org/PathwayBrowser/#/R-GGA-9842641 Active LTK receptor binds SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-9842651 https://reactome.org/PathwayBrowser/#/R-GGA-9842651 Active LTK receptor phosphorylates SHC1 IEA Gallus gallus A0A1D5NYP8 R-GGA-9842669 https://reactome.org/PathwayBrowser/#/R-GGA-9842669 Active LTK recruits GRB2:SOS1 IEA Gallus gallus A0A1D5NYQ5 R-GGA-425994 https://reactome.org/PathwayBrowser/#/R-GGA-425994 Na+/H+ exchanger transport (at cell membrane) IEA Gallus gallus A0A1D5NYR5 R-GGA-376419 https://reactome.org/PathwayBrowser/#/R-GGA-376419 Formation of NR-MED1 Coactivator Complex IEA Gallus gallus A0A1D5NYR5 R-GGA-382096 https://reactome.org/PathwayBrowser/#/R-GGA-382096 Formation of NR-NCOR Corepressor Complex IEA Gallus gallus A0A1D5NYS3 R-GGA-5682586 https://reactome.org/PathwayBrowser/#/R-GGA-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Gallus gallus A0A1D5NYS3 R-GGA-5682588 https://reactome.org/PathwayBrowser/#/R-GGA-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Gallus gallus A0A1D5NYS3 R-GGA-5682598 https://reactome.org/PathwayBrowser/#/R-GGA-5682598 ATM phosphorylates HERC2 IEA Gallus gallus A0A1D5NYS3 R-GGA-5682607 https://reactome.org/PathwayBrowser/#/R-GGA-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Gallus gallus A0A1D5NYS3 R-GGA-5682629 https://reactome.org/PathwayBrowser/#/R-GGA-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Gallus gallus A0A1D5NYS3 R-GGA-5682858 https://reactome.org/PathwayBrowser/#/R-GGA-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Gallus gallus A0A1D5NYS3 R-GGA-5682863 https://reactome.org/PathwayBrowser/#/R-GGA-5682863 RNF168 binds DNA DSBs IEA Gallus gallus A0A1D5NYS3 R-GGA-5683077 https://reactome.org/PathwayBrowser/#/R-GGA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Gallus gallus A0A1D5NYS3 R-GGA-5683384 https://reactome.org/PathwayBrowser/#/R-GGA-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Gallus gallus A0A1D5NYS3 R-GGA-5683385 https://reactome.org/PathwayBrowser/#/R-GGA-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Gallus gallus A0A1D5NYS3 R-GGA-5683425 https://reactome.org/PathwayBrowser/#/R-GGA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Gallus gallus A0A1D5NYS3 R-GGA-5683735 https://reactome.org/PathwayBrowser/#/R-GGA-5683735 CHEK2 is recruited to DNA DSBs IEA Gallus gallus A0A1D5NYS3 R-GGA-5683801 https://reactome.org/PathwayBrowser/#/R-GGA-5683801 CHEK2 phosphorylates BRCA1 IEA Gallus gallus A0A1D5NYS3 R-GGA-5684052 https://reactome.org/PathwayBrowser/#/R-GGA-5684052 PIAS4 SUMOylates MDC1 IEA Gallus gallus A0A1D5NYS3 R-GGA-5686685 https://reactome.org/PathwayBrowser/#/R-GGA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Gallus gallus A0A1D5NYS3 R-GGA-5686704 https://reactome.org/PathwayBrowser/#/R-GGA-5686704 Activated ATM phosphorylates DCLRE1C IEA Gallus gallus A0A1D5NYS3 R-GGA-5686900 https://reactome.org/PathwayBrowser/#/R-GGA-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Gallus gallus A0A1D5NYS3 R-GGA-5693551 https://reactome.org/PathwayBrowser/#/R-GGA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Gallus gallus A0A1D5NYS3 R-GGA-5693566 https://reactome.org/PathwayBrowser/#/R-GGA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Gallus gallus A0A1D5NYS3 R-GGA-69891 https://reactome.org/PathwayBrowser/#/R-GGA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Gallus gallus A0A1D5NYS9 R-GGA-9018758 https://reactome.org/PathwayBrowser/#/R-GGA-9018758 RHOH binds effectors at the plasma membrane IEA Gallus gallus A0A1D5NYU4 R-GGA-444126 https://reactome.org/PathwayBrowser/#/R-GGA-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Gallus gallus A0A1D5NYV1 R-GGA-111437 https://reactome.org/PathwayBrowser/#/R-GGA-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Gallus gallus A0A1D5NYV1 R-GGA-111438 https://reactome.org/PathwayBrowser/#/R-GGA-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Gallus gallus A0A1D5NYV1 R-GGA-77585 https://reactome.org/PathwayBrowser/#/R-GGA-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Gallus gallus A0A1D5NYV1 R-GGA-77586 https://reactome.org/PathwayBrowser/#/R-GGA-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Gallus gallus A0A1D5NYV7 R-GGA-202165 https://reactome.org/PathwayBrowser/#/R-GGA-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Gallus gallus A0A1D5NYV7 R-GGA-202168 https://reactome.org/PathwayBrowser/#/R-GGA-202168 Phosphorylation of ZAP-70 by Lck IEA Gallus gallus A0A1D5NYV7 R-GGA-202174 https://reactome.org/PathwayBrowser/#/R-GGA-202174 Activation of ZAP-70 IEA Gallus gallus A0A1D5NYV7 R-GGA-202214 https://reactome.org/PathwayBrowser/#/R-GGA-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Gallus gallus A0A1D5NYV7 R-GGA-202233 https://reactome.org/PathwayBrowser/#/R-GGA-202233 Inactivation of Lck by Csk IEA Gallus gallus A0A1D5NYV7 R-GGA-202248 https://reactome.org/PathwayBrowser/#/R-GGA-202248 Phosphorylation of PLC-gamma1 IEA Gallus gallus A0A1D5NYV7 R-GGA-202291 https://reactome.org/PathwayBrowser/#/R-GGA-202291 Activation of Lck IEA Gallus gallus A0A1D5NYV7 R-GGA-202344 https://reactome.org/PathwayBrowser/#/R-GGA-202344 Recruitment of ZAP-70 to phosphorylated ITAMs IEA Gallus gallus A0A1D5NYV7 R-GGA-2130641 https://reactome.org/PathwayBrowser/#/R-GGA-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Gallus gallus A0A1D5NYV7 R-GGA-2130725 https://reactome.org/PathwayBrowser/#/R-GGA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Gallus gallus A0A1D5NYV7 R-GGA-389758 https://reactome.org/PathwayBrowser/#/R-GGA-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Gallus gallus A0A1D5NYV7 R-GGA-8852200 https://reactome.org/PathwayBrowser/#/R-GGA-8852200 Inactivation of LCK by PTPN22 IEA Gallus gallus A0A1D5NYV7 R-GGA-8855381 https://reactome.org/PathwayBrowser/#/R-GGA-8855381 PTPN22 dephosphorylates ZAP70 IEA Gallus gallus A0A1D5NYV7 R-GGA-8951498 https://reactome.org/PathwayBrowser/#/R-GGA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Gallus gallus A0A1D5NYX9 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5NYX9 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5NYX9 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5NYX9 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5NYX9 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5NYY0 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus A0A1D5NYY0 R-GGA-9013022 https://reactome.org/PathwayBrowser/#/R-GGA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Gallus gallus A0A1D5NYY0 R-GGA-9013111 https://reactome.org/PathwayBrowser/#/R-GGA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Gallus gallus A0A1D5NYY0 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus A0A1D5NYY0 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus A0A1D5NYY0 R-GGA-9014295 https://reactome.org/PathwayBrowser/#/R-GGA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Gallus gallus A0A1D5NYY0 R-GGA-9014434 https://reactome.org/PathwayBrowser/#/R-GGA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Gallus gallus A0A1D5NYY0 R-GGA-9017488 https://reactome.org/PathwayBrowser/#/R-GGA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Gallus gallus A0A1D5NYY0 R-GGA-9018745 https://reactome.org/PathwayBrowser/#/R-GGA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Gallus gallus A0A1D5NYY0 R-GGA-9018806 https://reactome.org/PathwayBrowser/#/R-GGA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Gallus gallus A0A1D5NYY8 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5NYY9 R-GGA-6809521 https://reactome.org/PathwayBrowser/#/R-GGA-6809521 BPIF binds bacteria IEA Gallus gallus A0A1D5NYY9 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5NYZ1 R-GGA-390593 https://reactome.org/PathwayBrowser/#/R-GGA-390593 ATP Hydrolysis By Myosin IEA Gallus gallus A0A1D5NYZ1 R-GGA-390595 https://reactome.org/PathwayBrowser/#/R-GGA-390595 Calcium Binds Troponin-C IEA Gallus gallus A0A1D5NYZ1 R-GGA-390597 https://reactome.org/PathwayBrowser/#/R-GGA-390597 Release Of ADP From Myosin IEA Gallus gallus A0A1D5NYZ1 R-GGA-390598 https://reactome.org/PathwayBrowser/#/R-GGA-390598 Myosin Binds ATP IEA Gallus gallus A0A1D5NZ06 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A1D5NZ06 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A1D5NZ06 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A1D5NZ06 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A1D5NZ06 R-GGA-156808 https://reactome.org/PathwayBrowser/#/R-GGA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Gallus gallus A0A1D5NZ06 R-GGA-157849 https://reactome.org/PathwayBrowser/#/R-GGA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Gallus gallus A0A1D5NZ06 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5NZ06 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5NZ06 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1D5NZ06 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5NZ06 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5NZ06 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5NZ06 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A1D5NZ06 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus A0A1D5NZ06 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1D5NZ06 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1D5NZ06 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1D5NZ06 R-GGA-72676 https://reactome.org/PathwayBrowser/#/R-GGA-72676 eIF3 and eIF1A bind to the 40S subunit IEA Gallus gallus A0A1D5NZ06 R-GGA-72691 https://reactome.org/PathwayBrowser/#/R-GGA-72691 Formation of the 43S pre-initiation complex IEA Gallus gallus A0A1D5NZ06 R-GGA-72697 https://reactome.org/PathwayBrowser/#/R-GGA-72697 Start codon recognition IEA Gallus gallus A0A1D5NZ06 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1D5NZ06 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5NZ06 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5NZ06 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1D5NZ10 R-GGA-1247922 https://reactome.org/PathwayBrowser/#/R-GGA-1247922 GGCT transforms gGluCys to OPRO IEA Gallus gallus A0A1D5NZ11 R-GGA-5686685 https://reactome.org/PathwayBrowser/#/R-GGA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Gallus gallus A0A1D5NZ11 R-GGA-5686704 https://reactome.org/PathwayBrowser/#/R-GGA-5686704 Activated ATM phosphorylates DCLRE1C IEA Gallus gallus A0A1D5NZ11 R-GGA-5686900 https://reactome.org/PathwayBrowser/#/R-GGA-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Gallus gallus A0A1D5NZ12 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus A0A1D5NZ24 R-GGA-191763 https://reactome.org/PathwayBrowser/#/R-GGA-191763 snRNP:Snurportin complex formation IEA Gallus gallus A0A1D5NZ24 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1D5NZ30 R-GGA-6791227 https://reactome.org/PathwayBrowser/#/R-GGA-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Gallus gallus A0A1D5NZ43 R-GGA-428185 https://reactome.org/PathwayBrowser/#/R-GGA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Gallus gallus A0A1D5NZ54 R-GGA-189406 https://reactome.org/PathwayBrowser/#/R-GGA-189406 4 PBGs bind to form HMB IEA Gallus gallus A0A1D5NZ67 R-GGA-264615 https://reactome.org/PathwayBrowser/#/R-GGA-264615 Loading of acetylcholine in synaptic vesicles IEA Gallus gallus A0A1D5NZ67 R-GGA-372505 https://reactome.org/PathwayBrowser/#/R-GGA-372505 Acetylcholine synaptic vesicle docking and priming IEA Gallus gallus A0A1D5NZ67 R-GGA-8866277 https://reactome.org/PathwayBrowser/#/R-GGA-8866277 AP-2 directly binds some endocytic cargo IEA Gallus gallus A0A1D5NZ67 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5NZ67 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5NZ67 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5NZ67 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5NZ67 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5NZ67 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5NZ67 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5NZ67 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5NZ67 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5NZ67 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5NZ67 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5NZ67 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5NZ69 R-GGA-8938217 https://reactome.org/PathwayBrowser/#/R-GGA-8938217 RUNX1 binds the SWI/SNF complex IEA Gallus gallus A0A1D5NZ69 R-GGA-9933237 https://reactome.org/PathwayBrowser/#/R-GGA-9933237 PBRM1-containing ATPase complex binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD&:PHF10 IEA Gallus gallus A0A1D5NZ70 R-GGA-8848370 https://reactome.org/PathwayBrowser/#/R-GGA-8848370 IL18 binds IL18R1 IEA Gallus gallus A0A1D5NZ70 R-GGA-8848395 https://reactome.org/PathwayBrowser/#/R-GGA-8848395 IL18:IL18R1 binds IL18RAP IEA Gallus gallus A0A1D5NZ71 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5NZ71 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5NZ79 R-GGA-350567 https://reactome.org/PathwayBrowser/#/R-GGA-350567 Antizyme OAZ binds to Ornithine decarboxylase IEA Gallus gallus A0A1D5NZ79 R-GGA-350600 https://reactome.org/PathwayBrowser/#/R-GGA-350600 Antizyme inhibitor binds to OAZ and stablizes ODC complex IEA Gallus gallus A0A1D5NZ79 R-GGA-353125 https://reactome.org/PathwayBrowser/#/R-GGA-353125 26S proteosome degrades ODC holoenzyme complex IEA Gallus gallus A0A1D5NZ82 R-GGA-5173005 https://reactome.org/PathwayBrowser/#/R-GGA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Gallus gallus A0A1D5NZ82 R-GGA-5173192 https://reactome.org/PathwayBrowser/#/R-GGA-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Gallus gallus A0A1D5NZ92 R-GGA-9843978 https://reactome.org/PathwayBrowser/#/R-GGA-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1D5NZ92 R-GGA-994106 https://reactome.org/PathwayBrowser/#/R-GGA-994106 HP1 alpha binds Histone H3K9(me)3 IEA Gallus gallus A0A1D5NZA1 R-GGA-111439 https://reactome.org/PathwayBrowser/#/R-GGA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Gallus gallus A0A1D5NZA1 R-GGA-158441 https://reactome.org/PathwayBrowser/#/R-GGA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5NZA1 R-GGA-158447 https://reactome.org/PathwayBrowser/#/R-GGA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Gallus gallus A0A1D5NZA1 R-GGA-158481 https://reactome.org/PathwayBrowser/#/R-GGA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5NZA1 R-GGA-158484 https://reactome.org/PathwayBrowser/#/R-GGA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Gallus gallus A0A1D5NZA1 R-GGA-159046 https://reactome.org/PathwayBrowser/#/R-GGA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Gallus gallus A0A1D5NZA1 R-GGA-159050 https://reactome.org/PathwayBrowser/#/R-GGA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Gallus gallus A0A1D5NZA1 R-GGA-170825 https://reactome.org/PathwayBrowser/#/R-GGA-170825 NPC exports GCK1 from nucleus IEA Gallus gallus A0A1D5NZA1 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1D5NZA1 R-GGA-2990880 https://reactome.org/PathwayBrowser/#/R-GGA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Gallus gallus A0A1D5NZA1 R-GGA-2990882 https://reactome.org/PathwayBrowser/#/R-GGA-2990882 CDK1 phosphorylates NUP98 IEA Gallus gallus A0A1D5NZA1 R-GGA-4551649 https://reactome.org/PathwayBrowser/#/R-GGA-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Gallus gallus A0A1D5NZA1 R-GGA-4551679 https://reactome.org/PathwayBrowser/#/R-GGA-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Gallus gallus A0A1D5NZA1 R-GGA-4615872 https://reactome.org/PathwayBrowser/#/R-GGA-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Gallus gallus A0A1D5NZA1 R-GGA-4615987 https://reactome.org/PathwayBrowser/#/R-GGA-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Gallus gallus A0A1D5NZA1 R-GGA-4655355 https://reactome.org/PathwayBrowser/#/R-GGA-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Gallus gallus A0A1D5NZA1 R-GGA-5228523 https://reactome.org/PathwayBrowser/#/R-GGA-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Gallus gallus A0A1D5NZA1 R-GGA-5578744 https://reactome.org/PathwayBrowser/#/R-GGA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Gallus gallus A0A1D5NZA1 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1D5NZA1 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1D5NZA1 R-GGA-77587 https://reactome.org/PathwayBrowser/#/R-GGA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Gallus gallus A0A1D5NZB9 R-GGA-6793591 https://reactome.org/PathwayBrowser/#/R-GGA-6793591 LIAS synthesizes lipoyl-GCSH IEA Gallus gallus A0A1D5NZD2 R-GGA-8952044 https://reactome.org/PathwayBrowser/#/R-GGA-8952044 AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5NZD2 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5NZD2 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5NZD2 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5NZD2 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5NZD2 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5NZD2 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5NZF2 R-GGA-429860 https://reactome.org/PathwayBrowser/#/R-GGA-429860 DCP1-DCP2 complex decaps mRNA IEA Gallus gallus A0A1D5NZG8 R-GGA-5696415 https://reactome.org/PathwayBrowser/#/R-GGA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Gallus gallus A0A1D5NZJ2 R-GGA-9844006 https://reactome.org/PathwayBrowser/#/R-GGA-9844006 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) IEA Gallus gallus A0A1D5NZJ2 R-GGA-9844015 https://reactome.org/PathwayBrowser/#/R-GGA-9844015 MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin IEA Gallus gallus A0A1D5NZJ2 R-GGA-9844057 https://reactome.org/PathwayBrowser/#/R-GGA-9844057 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome IEA Gallus gallus A0A1D5NZL7 R-GGA-111879 https://reactome.org/PathwayBrowser/#/R-GGA-111879 PIP2 hydrolysis IEA Gallus gallus A0A1D5NZL7 R-GGA-112037 https://reactome.org/PathwayBrowser/#/R-GGA-112037 Inactivation of PLC beta IEA Gallus gallus A0A1D5NZL7 R-GGA-114688 https://reactome.org/PathwayBrowser/#/R-GGA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Gallus gallus A0A1D5NZL7 R-GGA-1855177 https://reactome.org/PathwayBrowser/#/R-GGA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Gallus gallus A0A1D5NZL7 R-GGA-398040 https://reactome.org/PathwayBrowser/#/R-GGA-398040 Gbeta:gamma activation of PLC beta IEA Gallus gallus A0A1D5NZL7 R-GGA-398193 https://reactome.org/PathwayBrowser/#/R-GGA-398193 PLC beta-mediated PIP2 hydrolysis IEA Gallus gallus A0A1D5NZL7 R-GGA-399998 https://reactome.org/PathwayBrowser/#/R-GGA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Gallus gallus A0A1D5NZL7 R-GGA-500717 https://reactome.org/PathwayBrowser/#/R-GGA-500717 Activation of GRIK3 homomer IEA Gallus gallus A0A1D5NZM5 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A1D5NZM5 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A1D5NZM5 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A1D5NZM5 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A1D5NZM5 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5NZM5 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5NZM5 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5NZM5 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5NZM5 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5NZM5 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A1D5NZM5 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1D5NZN5 R-GGA-3928578 https://reactome.org/PathwayBrowser/#/R-GGA-3928578 EPH receptors autophosphorylate IEA Gallus gallus A0A1D5NZN5 R-GGA-3928591 https://reactome.org/PathwayBrowser/#/R-GGA-3928591 EPH:EFN tetramers oligomerise IEA Gallus gallus A0A1D5NZN5 R-GGA-3928597 https://reactome.org/PathwayBrowser/#/R-GGA-3928597 EPH:EFN dimers tetramerise IEA Gallus gallus A0A1D5NZN5 R-GGA-3928604 https://reactome.org/PathwayBrowser/#/R-GGA-3928604 SFKs phosphorylate VAV2,3 IEA Gallus gallus A0A1D5NZN5 R-GGA-3928607 https://reactome.org/PathwayBrowser/#/R-GGA-3928607 p-EPHs bind VAV2,3 IEA Gallus gallus A0A1D5NZN5 R-GGA-3928628 https://reactome.org/PathwayBrowser/#/R-GGA-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5NZN5 R-GGA-3928642 https://reactome.org/PathwayBrowser/#/R-GGA-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5NZN5 R-GGA-3928646 https://reactome.org/PathwayBrowser/#/R-GGA-3928646 EPHAs bind EFNAs IEA Gallus gallus A0A1D5NZN5 R-GGA-3928651 https://reactome.org/PathwayBrowser/#/R-GGA-3928651 NGEF exchanges GTP for GDP on RHOA IEA Gallus gallus A0A1D5NZN5 R-GGA-4093327 https://reactome.org/PathwayBrowser/#/R-GGA-4093327 EPHA binds TIAM1 IEA Gallus gallus A0A1D5NZR7 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5NZR7 R-GGA-6809011 https://reactome.org/PathwayBrowser/#/R-GGA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Gallus gallus A0A1D5NZR7 R-GGA-6811431 https://reactome.org/PathwayBrowser/#/R-GGA-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Gallus gallus A0A1D5NZR7 R-GGA-6811433 https://reactome.org/PathwayBrowser/#/R-GGA-6811433 The COG tethering complex interacts with numerous SNAREs at the Golgi membrane IEA Gallus gallus A0A1D5NZR7 R-GGA-6814682 https://reactome.org/PathwayBrowser/#/R-GGA-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Gallus gallus A0A1D5NZR7 R-GGA-8849748 https://reactome.org/PathwayBrowser/#/R-GGA-8849748 The COG complex binds RABs at the Golgi membrane IEA Gallus gallus A0A1D5NZS8 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5NZS8 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1D5NZT5 R-GGA-1296127 https://reactome.org/PathwayBrowser/#/R-GGA-1296127 Activation of voltage gated Potassium channels IEA Gallus gallus A0A1D5NZT5 R-GGA-6798747 https://reactome.org/PathwayBrowser/#/R-GGA-6798747 Exocytosis of tertiary granule membrane proteins IEA Gallus gallus A0A1D5NZT5 R-GGA-6799350 https://reactome.org/PathwayBrowser/#/R-GGA-6799350 Exocytosis of specific granule membrane proteins IEA Gallus gallus A0A1D5NZU0 R-GGA-111439 https://reactome.org/PathwayBrowser/#/R-GGA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Gallus gallus A0A1D5NZU0 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A1D5NZU0 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A1D5NZU0 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A1D5NZU0 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A1D5NZU0 R-GGA-158441 https://reactome.org/PathwayBrowser/#/R-GGA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5NZU0 R-GGA-158447 https://reactome.org/PathwayBrowser/#/R-GGA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Gallus gallus A0A1D5NZU0 R-GGA-158481 https://reactome.org/PathwayBrowser/#/R-GGA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5NZU0 R-GGA-158484 https://reactome.org/PathwayBrowser/#/R-GGA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Gallus gallus A0A1D5NZU0 R-GGA-159046 https://reactome.org/PathwayBrowser/#/R-GGA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Gallus gallus A0A1D5NZU0 R-GGA-159050 https://reactome.org/PathwayBrowser/#/R-GGA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Gallus gallus A0A1D5NZU0 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5NZU0 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5NZU0 R-GGA-170825 https://reactome.org/PathwayBrowser/#/R-GGA-170825 NPC exports GCK1 from nucleus IEA Gallus gallus A0A1D5NZU0 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1D5NZU0 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5NZU0 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5NZU0 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5NZU0 R-GGA-2990880 https://reactome.org/PathwayBrowser/#/R-GGA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Gallus gallus A0A1D5NZU0 R-GGA-2990882 https://reactome.org/PathwayBrowser/#/R-GGA-2990882 CDK1 phosphorylates NUP98 IEA Gallus gallus A0A1D5NZU0 R-GGA-4551649 https://reactome.org/PathwayBrowser/#/R-GGA-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Gallus gallus A0A1D5NZU0 R-GGA-4551679 https://reactome.org/PathwayBrowser/#/R-GGA-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Gallus gallus A0A1D5NZU0 R-GGA-4615872 https://reactome.org/PathwayBrowser/#/R-GGA-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Gallus gallus A0A1D5NZU0 R-GGA-4615987 https://reactome.org/PathwayBrowser/#/R-GGA-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Gallus gallus A0A1D5NZU0 R-GGA-4655355 https://reactome.org/PathwayBrowser/#/R-GGA-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Gallus gallus A0A1D5NZU0 R-GGA-5228523 https://reactome.org/PathwayBrowser/#/R-GGA-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Gallus gallus A0A1D5NZU0 R-GGA-5578744 https://reactome.org/PathwayBrowser/#/R-GGA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Gallus gallus A0A1D5NZU0 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A1D5NZU0 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1D5NZU0 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1D5NZU0 R-GGA-77587 https://reactome.org/PathwayBrowser/#/R-GGA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Gallus gallus A0A1D5NZU0 R-GGA-9615901 https://reactome.org/PathwayBrowser/#/R-GGA-9615901 AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex IEA Gallus gallus A0A1D5NZU0 R-GGA-9618378 https://reactome.org/PathwayBrowser/#/R-GGA-9618378 POM121 binds the Nup107-Nup160 complex IEA Gallus gallus A0A1D5NZU0 R-GGA-9634169 https://reactome.org/PathwayBrowser/#/R-GGA-9634169 POM121 and NDC1 bind the Nup93 complex IEA Gallus gallus A0A1D5NZU0 R-GGA-9639287 https://reactome.org/PathwayBrowser/#/R-GGA-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Gallus gallus A0A1D5NZU0 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus A0A1D5NZU0 R-GGA-9640237 https://reactome.org/PathwayBrowser/#/R-GGA-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Gallus gallus A0A1D5NZU0 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1D5NZU0 R-GGA-9657619 https://reactome.org/PathwayBrowser/#/R-GGA-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 IEA Gallus gallus A0A1D5NZU4 R-GGA-380311 https://reactome.org/PathwayBrowser/#/R-GGA-380311 Recruitment of Plk1 to centrosomes IEA Gallus gallus A0A1D5NZU4 R-GGA-380455 https://reactome.org/PathwayBrowser/#/R-GGA-380455 Recruitment of CDK11p58 to the centrosomes IEA Gallus gallus A0A1D5NZU8 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5NZU8 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5NZU8 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5NZU8 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5NZU8 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5NZW2 R-GGA-200512 https://reactome.org/PathwayBrowser/#/R-GGA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus A0A1D5NZW4 R-GGA-428690 https://reactome.org/PathwayBrowser/#/R-GGA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Gallus gallus A0A1D5NZW4 R-GGA-428696 https://reactome.org/PathwayBrowser/#/R-GGA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Gallus gallus A0A1D5NZW8 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus A0A1D5NZW8 R-GGA-400586 https://reactome.org/PathwayBrowser/#/R-GGA-400586 G alpha (q) binds to Trio family RhoGEFs IEA Gallus gallus A0A1D5NZW8 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus A0A1D5NZW8 R-GGA-8980691 https://reactome.org/PathwayBrowser/#/R-GGA-8980691 RHOA GEFs activate RHOA IEA Gallus gallus A0A1D5NZW8 R-GGA-9013143 https://reactome.org/PathwayBrowser/#/R-GGA-9013143 RAC1 GEFs activate RAC1 IEA Gallus gallus A0A1D5NZW8 R-GGA-9013159 https://reactome.org/PathwayBrowser/#/R-GGA-9013159 CDC42 GEFs activate CDC42 IEA Gallus gallus A0A1D5NZW8 R-GGA-9014296 https://reactome.org/PathwayBrowser/#/R-GGA-9014296 RAC2 GEFs activate RAC2 IEA Gallus gallus A0A1D5NZW8 R-GGA-9014433 https://reactome.org/PathwayBrowser/#/R-GGA-9014433 RHOG GEFs activate RHOG IEA Gallus gallus A0A1D5NZW8 R-GGA-9017491 https://reactome.org/PathwayBrowser/#/R-GGA-9017491 RHOJ GEFs activate RHOJ IEA Gallus gallus A0A1D5NZW8 R-GGA-9018804 https://reactome.org/PathwayBrowser/#/R-GGA-9018804 RAC3 GEFs activate RAC3 IEA Gallus gallus A0A1D5NZX9 R-GGA-166041 https://reactome.org/PathwayBrowser/#/R-GGA-166041 Transfer of LPS onto TLR4 IEA Gallus gallus A0A1D5NZX9 R-GGA-166175 https://reactome.org/PathwayBrowser/#/R-GGA-166175 TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) IEA Gallus gallus A0A1D5NZX9 R-GGA-166245 https://reactome.org/PathwayBrowser/#/R-GGA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Gallus gallus A0A1D5NZX9 R-GGA-166271 https://reactome.org/PathwayBrowser/#/R-GGA-166271 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 IEA Gallus gallus A0A1D5NZX9 R-GGA-168915 https://reactome.org/PathwayBrowser/#/R-GGA-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex IEA Gallus gallus A0A1D5NZX9 R-GGA-168921 https://reactome.org/PathwayBrowser/#/R-GGA-168921 TRIF:activated TLR3/TLR4 complex recruits RIP1 IEA Gallus gallus A0A1D5NZX9 R-GGA-2201293 https://reactome.org/PathwayBrowser/#/R-GGA-2201293 Endocytosis of TLR4:LY96:LPS:CD14 IEA Gallus gallus A0A1D5NZX9 R-GGA-2201338 https://reactome.org/PathwayBrowser/#/R-GGA-2201338 TRAF3 binds TICAM1:activated TLR4 complex IEA Gallus gallus A0A1D5NZX9 R-GGA-2213017 https://reactome.org/PathwayBrowser/#/R-GGA-2213017 Auto-ubiquitination of TRAF3 IEA Gallus gallus A0A1D5NZX9 R-GGA-2562541 https://reactome.org/PathwayBrowser/#/R-GGA-2562541 TLR4-induced ripoptosome assembly IEA Gallus gallus A0A1D5NZX9 R-GGA-2562564 https://reactome.org/PathwayBrowser/#/R-GGA-2562564 Caspase-8 processing within TLR4 complex IEA Gallus gallus A0A1D5NZX9 R-GGA-450358 https://reactome.org/PathwayBrowser/#/R-GGA-450358 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation IEA Gallus gallus A0A1D5NZX9 R-GGA-5362486 https://reactome.org/PathwayBrowser/#/R-GGA-5362486 TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4 IEA Gallus gallus A0A1D5NZX9 R-GGA-5362500 https://reactome.org/PathwayBrowser/#/R-GGA-5362500 TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Gallus gallus A0A1D5NZX9 R-GGA-5432825 https://reactome.org/PathwayBrowser/#/R-GGA-5432825 HMGB1 binds TLR4:LY96 IEA Gallus gallus A0A1D5NZX9 R-GGA-5432849 https://reactome.org/PathwayBrowser/#/R-GGA-5432849 S100A8:S100A9 binds TLR4:LY96 IEA Gallus gallus A0A1D5NZX9 R-GGA-5432852 https://reactome.org/PathwayBrowser/#/R-GGA-5432852 SFTPA/SFTPD binds TLR4:LY96 IEA Gallus gallus A0A1D5NZX9 R-GGA-6805943 https://reactome.org/PathwayBrowser/#/R-GGA-6805943 S100A1 binds TLR4:LY96 IEA Gallus gallus A0A1D5NZX9 R-GGA-8870678 https://reactome.org/PathwayBrowser/#/R-GGA-8870678 Cleaved fibrinogen products bind TLR4:LY96 IEA Gallus gallus A0A1D5NZX9 R-GGA-936947 https://reactome.org/PathwayBrowser/#/R-GGA-936947 Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex IEA Gallus gallus A0A1D5NZX9 R-GGA-936951 https://reactome.org/PathwayBrowser/#/R-GGA-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Gallus gallus A0A1D5NZX9 R-GGA-936952 https://reactome.org/PathwayBrowser/#/R-GGA-936952 Auto ubiquitination of TRAF6 bound to the activated TLR4 complex IEA Gallus gallus A0A1D5NZX9 R-GGA-936985 https://reactome.org/PathwayBrowser/#/R-GGA-936985 Activated TLR4:TICAM1 recruits TRAF6 IEA Gallus gallus A0A1D5NZX9 R-GGA-937075 https://reactome.org/PathwayBrowser/#/R-GGA-937075 Phosphorylated TAK1 leaves activated TLR receptor complex IEA Gallus gallus A0A1D5NZX9 R-GGA-9707594 https://reactome.org/PathwayBrowser/#/R-GGA-9707594 Hemes bind LY96 IEA Gallus gallus A0A1D5NZX9 R-GGA-9707659 https://reactome.org/PathwayBrowser/#/R-GGA-9707659 Hemes:LY96 activates TLR4 IEA Gallus gallus A0A1D5NZX9 R-GGA-9823904 https://reactome.org/PathwayBrowser/#/R-GGA-9823904 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Gallus gallus A0A1D5NZX9 R-GGA-9823906 https://reactome.org/PathwayBrowser/#/R-GGA-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Gallus gallus A0A1D5NZX9 R-GGA-9823910 https://reactome.org/PathwayBrowser/#/R-GGA-9823910 Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Gallus gallus A0A1D5NZX9 R-GGA-9823932 https://reactome.org/PathwayBrowser/#/R-GGA-9823932 Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Gallus gallus A0A1D5NZX9 R-GGA-9823934 https://reactome.org/PathwayBrowser/#/R-GGA-9823934 OPTN binds TBK1 within the activated TLR4 complex IEA Gallus gallus A0A1D5NZX9 R-GGA-9823939 https://reactome.org/PathwayBrowser/#/R-GGA-9823939 IKKε (IKBKE) is ubiquitinated within the activated TLR4 IEA Gallus gallus A0A1D5NZX9 R-GGA-9824882 https://reactome.org/PathwayBrowser/#/R-GGA-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Gallus gallus A0A1D5NZZ2 R-GGA-9018794 https://reactome.org/PathwayBrowser/#/R-GGA-9018794 RHOV binds effectors at the plasma membrane IEA Gallus gallus A0A1D5NZZ5 R-GGA-8878117 https://reactome.org/PathwayBrowser/#/R-GGA-8878117 RUNX3 binds ZFHX3 IEA Gallus gallus A0A1D5P008 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5P072 R-GGA-9865630 https://reactome.org/PathwayBrowser/#/R-GGA-9865630 Metallochaperone inserts 2Cu2+ into MT-CO2 IEA Gallus gallus A0A1D5P088 R-GGA-376419 https://reactome.org/PathwayBrowser/#/R-GGA-376419 Formation of NR-MED1 Coactivator Complex IEA Gallus gallus A0A1D5P088 R-GGA-382096 https://reactome.org/PathwayBrowser/#/R-GGA-382096 Formation of NR-NCOR Corepressor Complex IEA Gallus gallus A0A1D5P088 R-GGA-4090390 https://reactome.org/PathwayBrowser/#/R-GGA-4090390 PIAS1,2-1 SUMOylates AR with SUMO1 IEA Gallus gallus A0A1D5P088 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus A0A1D5P088 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus A0A1D5P088 R-GGA-5625784 https://reactome.org/PathwayBrowser/#/R-GGA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Gallus gallus A0A1D5P088 R-GGA-5625796 https://reactome.org/PathwayBrowser/#/R-GGA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Gallus gallus A0A1D5P088 R-GGA-5625797 https://reactome.org/PathwayBrowser/#/R-GGA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Gallus gallus A0A1D5P088 R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus A0A1D5P088 R-GGA-5625849 https://reactome.org/PathwayBrowser/#/R-GGA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Gallus gallus A0A1D5P088 R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus A0A1D5P088 R-GGA-5696605 https://reactome.org/PathwayBrowser/#/R-GGA-5696605 USP12, USP26 deubiquitinate AR IEA Gallus gallus A0A1D5P088 R-GGA-8877902 https://reactome.org/PathwayBrowser/#/R-GGA-8877902 Activated AR binds RUNX2 IEA Gallus gallus A0A1D5P088 R-GGA-9705925 https://reactome.org/PathwayBrowser/#/R-GGA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Gallus gallus A0A1D5P088 R-GGA-9705926 https://reactome.org/PathwayBrowser/#/R-GGA-9705926 AR binds AR agonists IEA Gallus gallus A0A1D5P088 R-GGA-9706837 https://reactome.org/PathwayBrowser/#/R-GGA-9706837 AR binds AR antagonists IEA Gallus gallus A0A1D5P090 R-GGA-6807868 https://reactome.org/PathwayBrowser/#/R-GGA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Gallus gallus A0A1D5P090 R-GGA-6807872 https://reactome.org/PathwayBrowser/#/R-GGA-6807872 Active ARF recruits coatomer IEA Gallus gallus A0A1D5P090 R-GGA-6807877 https://reactome.org/PathwayBrowser/#/R-GGA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Gallus gallus A0A1D5P090 R-GGA-6811417 https://reactome.org/PathwayBrowser/#/R-GGA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Gallus gallus A0A1D5P090 R-GGA-6811418 https://reactome.org/PathwayBrowser/#/R-GGA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Gallus gallus A0A1D5P092 R-GGA-1454928 https://reactome.org/PathwayBrowser/#/R-GGA-1454928 ABCG4 may mediate cholesterol efflux IEA Gallus gallus A0A1D5P0A1 R-GGA-70286 https://reactome.org/PathwayBrowser/#/R-GGA-70286 UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose IEA Gallus gallus A0A1D5P0B3 R-GGA-5684862 https://reactome.org/PathwayBrowser/#/R-GGA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region IEA Gallus gallus A0A1D5P0B3 R-GGA-5684864 https://reactome.org/PathwayBrowser/#/R-GGA-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Gallus gallus A0A1D5P0B3 R-GGA-5684865 https://reactome.org/PathwayBrowser/#/R-GGA-5684865 SFTPB dimer,C translocate from multivesicle body to lamellar body IEA Gallus gallus A0A1D5P0B3 R-GGA-6791016 https://reactome.org/PathwayBrowser/#/R-GGA-6791016 SFTPB binds itself IEA Gallus gallus A0A1D5P0B3 R-GGA-9624789 https://reactome.org/PathwayBrowser/#/R-GGA-9624789 pro-SFTPB translocates from ER membrane to multivesicle body IEA Gallus gallus A0A1D5P0B5 R-GGA-8952630 https://reactome.org/PathwayBrowser/#/R-GGA-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P0B5 R-GGA-8952631 https://reactome.org/PathwayBrowser/#/R-GGA-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P0B5 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5P0B5 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5P0B5 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5P0B5 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5P0B5 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5P0B5 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5P0B9 R-GGA-430028 https://reactome.org/PathwayBrowser/#/R-GGA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Gallus gallus A0A1D5P0B9 R-GGA-450488 https://reactome.org/PathwayBrowser/#/R-GGA-450488 BRF1 Complex recruits RNA degradation activities IEA Gallus gallus A0A1D5P0B9 R-GGA-6791222 https://reactome.org/PathwayBrowser/#/R-GGA-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Gallus gallus A0A1D5P0B9 R-GGA-9933575 https://reactome.org/PathwayBrowser/#/R-GGA-9933575 MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome IEA Gallus gallus A0A1D5P0B9 R-GGA-9934522 https://reactome.org/PathwayBrowser/#/R-GGA-9934522 NEXT:ZC3H18:CBCA:m7GpppN-RNA binds the RNA exosome IEA Gallus gallus A0A1D5P0C4 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus A0A1D5P0C4 R-GGA-3928627 https://reactome.org/PathwayBrowser/#/R-GGA-3928627 EPHB phosphorylates TIAM1 IEA Gallus gallus A0A1D5P0C4 R-GGA-3928642 https://reactome.org/PathwayBrowser/#/R-GGA-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5P0C4 R-GGA-3928645 https://reactome.org/PathwayBrowser/#/R-GGA-3928645 EPHB:NMDAR binds TIAM1 IEA Gallus gallus A0A1D5P0C4 R-GGA-4093327 https://reactome.org/PathwayBrowser/#/R-GGA-4093327 EPHA binds TIAM1 IEA Gallus gallus A0A1D5P0C4 R-GGA-4093336 https://reactome.org/PathwayBrowser/#/R-GGA-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5P0C4 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus A0A1D5P0C4 R-GGA-8980691 https://reactome.org/PathwayBrowser/#/R-GGA-8980691 RHOA GEFs activate RHOA IEA Gallus gallus A0A1D5P0C4 R-GGA-9013143 https://reactome.org/PathwayBrowser/#/R-GGA-9013143 RAC1 GEFs activate RAC1 IEA Gallus gallus A0A1D5P0C4 R-GGA-9013159 https://reactome.org/PathwayBrowser/#/R-GGA-9013159 CDC42 GEFs activate CDC42 IEA Gallus gallus A0A1D5P0C4 R-GGA-9014296 https://reactome.org/PathwayBrowser/#/R-GGA-9014296 RAC2 GEFs activate RAC2 IEA Gallus gallus A0A1D5P0C4 R-GGA-9018804 https://reactome.org/PathwayBrowser/#/R-GGA-9018804 RAC3 GEFs activate RAC3 IEA Gallus gallus A0A1D5P0D0 R-GGA-4419978 https://reactome.org/PathwayBrowser/#/R-GGA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Gallus gallus A0A1D5P0E2 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus A0A1D5P0E2 R-GGA-203979 https://reactome.org/PathwayBrowser/#/R-GGA-203979 Coat Assembly IEA Gallus gallus A0A1D5P0E2 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus A0A1D5P0E2 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus A0A1D5P0E2 R-GGA-5694413 https://reactome.org/PathwayBrowser/#/R-GGA-5694413 SEC4C,D bind GOSR2 and STX5 IEA Gallus gallus A0A1D5P0E2 R-GGA-5694415 https://reactome.org/PathwayBrowser/#/R-GGA-5694415 SEC24A,B:SEC23A bind SEC22B IEA Gallus gallus A0A1D5P0E2 R-GGA-5694417 https://reactome.org/PathwayBrowser/#/R-GGA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Gallus gallus A0A1D5P0E2 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus A0A1D5P0E2 R-GGA-5694446 https://reactome.org/PathwayBrowser/#/R-GGA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Gallus gallus A0A1D5P0E2 R-GGA-5694522 https://reactome.org/PathwayBrowser/#/R-GGA-5694522 Inner coat assembly and cargo binding IEA Gallus gallus A0A1D5P0E2 R-GGA-5694527 https://reactome.org/PathwayBrowser/#/R-GGA-5694527 Loss of SAR1B GTPase IEA Gallus gallus A0A1D5P0E2 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus A0A1D5P0E2 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus A0A1D5P0E2 R-GGA-983425 https://reactome.org/PathwayBrowser/#/R-GGA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Gallus gallus A0A1D5P0E4 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1D5P0E4 R-GGA-9842833 https://reactome.org/PathwayBrowser/#/R-GGA-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Gallus gallus A0A1D5P0E4 R-GGA-9842835 https://reactome.org/PathwayBrowser/#/R-GGA-9842835 KRAB-ZFP binds retroelement DNA in chromatin IEA Gallus gallus A0A1D5P0E4 R-GGA-9842839 https://reactome.org/PathwayBrowser/#/R-GGA-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1D5P0E4 R-GGA-9843978 https://reactome.org/PathwayBrowser/#/R-GGA-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1D5P0F4 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus A0A1D5P0F4 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus A0A1D5P0F4 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus A0A1D5P0F4 R-GGA-1981120 https://reactome.org/PathwayBrowser/#/R-GGA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Gallus gallus A0A1D5P0F4 R-GGA-2002460 https://reactome.org/PathwayBrowser/#/R-GGA-2002460 P4HB binds Collagen chains IEA Gallus gallus A0A1D5P0F4 R-GGA-2089971 https://reactome.org/PathwayBrowser/#/R-GGA-2089971 Secretion of collagens IEA Gallus gallus A0A1D5P0F4 R-GGA-2213205 https://reactome.org/PathwayBrowser/#/R-GGA-2213205 Type XII and XIV collagens associate with type I and type II fibrils IEA Gallus gallus A0A1D5P0F4 R-GGA-8944236 https://reactome.org/PathwayBrowser/#/R-GGA-8944236 Association of procollagen type XIV IEA Gallus gallus A0A1D5P0F4 R-GGA-8948228 https://reactome.org/PathwayBrowser/#/R-GGA-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Gallus gallus A0A1D5P0F4 R-GGA-8948231 https://reactome.org/PathwayBrowser/#/R-GGA-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Gallus gallus A0A1D5P0F4 R-GGA-8948232 https://reactome.org/PathwayBrowser/#/R-GGA-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Gallus gallus A0A1D5P0F4 R-GGA-8948234 https://reactome.org/PathwayBrowser/#/R-GGA-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Gallus gallus A0A1D5P0F9 R-GGA-5683714 https://reactome.org/PathwayBrowser/#/R-GGA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Gallus gallus A0A1D5P0I0 R-GGA-375339 https://reactome.org/PathwayBrowser/#/R-GGA-375339 Pannexin 1/Pannexin2 mediated neuronal gap junction communication IEA Gallus gallus A0A1D5P0I0 R-GGA-877198 https://reactome.org/PathwayBrowser/#/R-GGA-877198 P2X7 mediates membrane pores that include pannexin-1 IEA Gallus gallus A0A1D5P0J0 R-GGA-111930 https://reactome.org/PathwayBrowser/#/R-GGA-111930 Adenylate cyclase produces cAMP IEA Gallus gallus A0A1D5P0J0 R-GGA-170666 https://reactome.org/PathwayBrowser/#/R-GGA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Gallus gallus A0A1D5P0J0 R-GGA-170671 https://reactome.org/PathwayBrowser/#/R-GGA-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Gallus gallus A0A1D5P0J0 R-GGA-170672 https://reactome.org/PathwayBrowser/#/R-GGA-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Gallus gallus A0A1D5P0J0 R-GGA-170674 https://reactome.org/PathwayBrowser/#/R-GGA-170674 Dissociation of the Gi alpha:G olf complex IEA Gallus gallus A0A1D5P0J0 R-GGA-170676 https://reactome.org/PathwayBrowser/#/R-GGA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Gallus gallus A0A1D5P0J0 R-GGA-170677 https://reactome.org/PathwayBrowser/#/R-GGA-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Gallus gallus A0A1D5P0J0 R-GGA-170685 https://reactome.org/PathwayBrowser/#/R-GGA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Gallus gallus A0A1D5P0J0 R-GGA-170686 https://reactome.org/PathwayBrowser/#/R-GGA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Gallus gallus A0A1D5P0J0 R-GGA-392064 https://reactome.org/PathwayBrowser/#/R-GGA-392064 G alpha (z) inhibits adenylate cyclase IEA Gallus gallus A0A1D5P0J0 R-GGA-5610727 https://reactome.org/PathwayBrowser/#/R-GGA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Gallus gallus A0A1D5P0J6 R-GGA-71188 https://reactome.org/PathwayBrowser/#/R-GGA-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Gallus gallus A0A1D5P0L1 R-GGA-2029465 https://reactome.org/PathwayBrowser/#/R-GGA-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Gallus gallus A0A1D5P0L1 R-GGA-2029466 https://reactome.org/PathwayBrowser/#/R-GGA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Gallus gallus A0A1D5P0L1 R-GGA-2029469 https://reactome.org/PathwayBrowser/#/R-GGA-2029469 p-ERK phosphorylates WAVEs and ABI IEA Gallus gallus A0A1D5P0L1 R-GGA-2130194 https://reactome.org/PathwayBrowser/#/R-GGA-2130194 ABL phosphorylates WAVEs IEA Gallus gallus A0A1D5P0L1 R-GGA-2197690 https://reactome.org/PathwayBrowser/#/R-GGA-2197690 Detachment of WASP/WAVE IEA Gallus gallus A0A1D5P0L1 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5P0L1 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5P0L4 R-GGA-189442 https://reactome.org/PathwayBrowser/#/R-GGA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Gallus gallus A0A1D5P0N2 R-GGA-9856465 https://reactome.org/PathwayBrowser/#/R-GGA-9856465 MLPH/MYRIP bind GGC-RAB27A and MYO5A IEA Gallus gallus A0A1D5P0N6 R-GGA-2684901 https://reactome.org/PathwayBrowser/#/R-GGA-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Gallus gallus A0A1D5P0R2 R-GGA-265177 https://reactome.org/PathwayBrowser/#/R-GGA-265177 Exocyst complex formation IEA Gallus gallus A0A1D5P0R2 R-GGA-5623524 https://reactome.org/PathwayBrowser/#/R-GGA-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Gallus gallus A0A1D5P0R2 R-GGA-5623527 https://reactome.org/PathwayBrowser/#/R-GGA-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Gallus gallus A0A1D5P0T5 R-GGA-113504 https://reactome.org/PathwayBrowser/#/R-GGA-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Gallus gallus A0A1D5P0T5 R-GGA-174425 https://reactome.org/PathwayBrowser/#/R-GGA-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Gallus gallus A0A1D5P0T5 R-GGA-174427 https://reactome.org/PathwayBrowser/#/R-GGA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Gallus gallus A0A1D5P0T5 R-GGA-174452 https://reactome.org/PathwayBrowser/#/R-GGA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Gallus gallus A0A1D5P0T5 R-GGA-68913 https://reactome.org/PathwayBrowser/#/R-GGA-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Gallus gallus A0A1D5P0T5 R-GGA-68914 https://reactome.org/PathwayBrowser/#/R-GGA-68914 DNA polymerase alpha:primase binds at the origin IEA Gallus gallus A0A1D5P0T5 R-GGA-68950 https://reactome.org/PathwayBrowser/#/R-GGA-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Gallus gallus A0A1D5P0T5 R-GGA-69053 https://reactome.org/PathwayBrowser/#/R-GGA-69053 RFC binding displaces Pol Alpha IEA Gallus gallus A0A1D5P0T5 R-GGA-69063 https://reactome.org/PathwayBrowser/#/R-GGA-69063 Loading of PCNA - Sliding Clamp Formation IEA Gallus gallus A0A1D5P0T5 R-GGA-69068 https://reactome.org/PathwayBrowser/#/R-GGA-69068 RFC dissociates after sliding clamp formation IEA Gallus gallus A0A1D5P0U5 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus A0A1D5P0U5 R-GGA-8951499 https://reactome.org/PathwayBrowser/#/R-GGA-8951499 Loading of antigenic peptides on to class I MHC IEA Gallus gallus A0A1D5P0U5 R-GGA-901047 https://reactome.org/PathwayBrowser/#/R-GGA-901047 Binding of ERp57 IEA Gallus gallus A0A1D5P0V5 R-GGA-6785636 https://reactome.org/PathwayBrowser/#/R-GGA-6785636 Phosphorylated ERBB2 heterodimers bind MEMO1 IEA Gallus gallus A0A1D5P0X4 R-GGA-1592362 https://reactome.org/PathwayBrowser/#/R-GGA-1592362 Activation of proMMP7 by MMP3 IEA Gallus gallus A0A1D5P0X4 R-GGA-1604752 https://reactome.org/PathwayBrowser/#/R-GGA-1604752 Initial activation of proMMP13 by MMP3 IEA Gallus gallus A0A1D5P0X4 R-GGA-2130706 https://reactome.org/PathwayBrowser/#/R-GGA-2130706 MHC class II antigen processing IEA Gallus gallus A0A1D5P0X4 R-GGA-2514772 https://reactome.org/PathwayBrowser/#/R-GGA-2514772 Fibrillin-1 degradation by MMP3, CTSK, CTSL2 IEA Gallus gallus A0A1D5P0X4 R-GGA-8938121 https://reactome.org/PathwayBrowser/#/R-GGA-8938121 SERPINB13 binds CTSK IEA Gallus gallus A0A1D5P0X6 R-GGA-6814555 https://reactome.org/PathwayBrowser/#/R-GGA-6814555 Integrator complex processes the 3' end of snRNA IEA Gallus gallus A0A1D5P0X6 R-GGA-6814559 https://reactome.org/PathwayBrowser/#/R-GGA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Gallus gallus A0A1D5P0Z3 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus A0A1D5P111 R-GGA-5578910 https://reactome.org/PathwayBrowser/#/R-GGA-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Gallus gallus A0A1D5P116 R-GGA-8938217 https://reactome.org/PathwayBrowser/#/R-GGA-8938217 RUNX1 binds the SWI/SNF complex IEA Gallus gallus A0A1D5P116 R-GGA-9932448 https://reactome.org/PathwayBrowser/#/R-GGA-9932448 SMARCC binds SMARCD IEA Gallus gallus A0A1D5P116 R-GGA-9932449 https://reactome.org/PathwayBrowser/#/R-GGA-9932449 SMARCE1 and SMARCB1 bind SMARCC dimer:SMARCDs IEA Gallus gallus A0A1D5P116 R-GGA-9932832 https://reactome.org/PathwayBrowser/#/R-GGA-9932832 BRD7 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2 IEA Gallus gallus A0A1D5P116 R-GGA-9932843 https://reactome.org/PathwayBrowser/#/R-GGA-9932843 PHF10 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD7 IEA Gallus gallus A0A1D5P116 R-GGA-9933236 https://reactome.org/PathwayBrowser/#/R-GGA-9933236 SS18-containing ATPase complex binds SMARCC dimer:SMARCDs:BICRAs:BRD9 IEA Gallus gallus A0A1D5P116 R-GGA-9933237 https://reactome.org/PathwayBrowser/#/R-GGA-9933237 PBRM1-containing ATPase complex binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD&:PHF10 IEA Gallus gallus A0A1D5P116 R-GGA-9934021 https://reactome.org/PathwayBrowser/#/R-GGA-9934021 Formation of neuronal progenitor BAF (npBAF) IEA Gallus gallus A0A1D5P116 R-GGA-9934022 https://reactome.org/PathwayBrowser/#/R-GGA-9934022 DPF2, PHF10 bind SMARCC1:SMARCC2 dimer:SMARD1:ARID1A IEA Gallus gallus A0A1D5P116 R-GGA-9934024 https://reactome.org/PathwayBrowser/#/R-GGA-9934024 SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10 IEA Gallus gallus A0A1D5P116 R-GGA-9934026 https://reactome.org/PathwayBrowser/#/R-GGA-9934026 SMARCE1 and SMARCB1 bind SMARCC1:SMARCC2 dimer:SMARCD1 IEA Gallus gallus A0A1D5P116 R-GGA-9934027 https://reactome.org/PathwayBrowser/#/R-GGA-9934027 SMARCC1 and SMARCC2 bind SMARCD1 IEA Gallus gallus A0A1D5P117 R-GGA-112385 https://reactome.org/PathwayBrowser/#/R-GGA-112385 Addition of nucleotides leads to transcript elongation IEA Gallus gallus A0A1D5P117 R-GGA-112392 https://reactome.org/PathwayBrowser/#/R-GGA-112392 Resumption of elongation after recovery from pausing IEA Gallus gallus A0A1D5P117 R-GGA-112395 https://reactome.org/PathwayBrowser/#/R-GGA-112395 Abortive termination of elongation after arrest IEA Gallus gallus A0A1D5P117 R-GGA-112396 https://reactome.org/PathwayBrowser/#/R-GGA-112396 Separation of elongating transcript from template IEA Gallus gallus A0A1D5P117 R-GGA-113411 https://reactome.org/PathwayBrowser/#/R-GGA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Gallus gallus A0A1D5P117 R-GGA-113412 https://reactome.org/PathwayBrowser/#/R-GGA-113412 Pol II elongation complex moves on the template as transcript elongates IEA Gallus gallus A0A1D5P117 R-GGA-113413 https://reactome.org/PathwayBrowser/#/R-GGA-113413 TFIIS-mediated recovery of elongation from arrest IEA Gallus gallus A0A1D5P117 R-GGA-113414 https://reactome.org/PathwayBrowser/#/R-GGA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Gallus gallus A0A1D5P138 R-GGA-372505 https://reactome.org/PathwayBrowser/#/R-GGA-372505 Acetylcholine synaptic vesicle docking and priming IEA Gallus gallus A0A1D5P138 R-GGA-374922 https://reactome.org/PathwayBrowser/#/R-GGA-374922 Noradrenalin synaptic vesicle docking and priming IEA Gallus gallus A0A1D5P138 R-GGA-388824 https://reactome.org/PathwayBrowser/#/R-GGA-388824 PTPRF, PTPRS, PTPRD bind Liprins IEA Gallus gallus A0A1D5P140 R-GGA-9018778 https://reactome.org/PathwayBrowser/#/R-GGA-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Gallus gallus A0A1D5P146 R-GGA-5358510 https://reactome.org/PathwayBrowser/#/R-GGA-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Gallus gallus A0A1D5P146 R-GGA-5358518 https://reactome.org/PathwayBrowser/#/R-GGA-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Gallus gallus A0A1D5P146 R-GGA-5358597 https://reactome.org/PathwayBrowser/#/R-GGA-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Gallus gallus A0A1D5P146 R-GGA-5358599 https://reactome.org/PathwayBrowser/#/R-GGA-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Gallus gallus A0A1D5P146 R-GGA-5444523 https://reactome.org/PathwayBrowser/#/R-GGA-5444523 Formation of MSH1:PMS2 Complex IEA Gallus gallus A0A1D5P158 R-GGA-265177 https://reactome.org/PathwayBrowser/#/R-GGA-265177 Exocyst complex formation IEA Gallus gallus A0A1D5P158 R-GGA-5623524 https://reactome.org/PathwayBrowser/#/R-GGA-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Gallus gallus A0A1D5P158 R-GGA-5623527 https://reactome.org/PathwayBrowser/#/R-GGA-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Gallus gallus A0A1D5P167 R-GGA-6798745 https://reactome.org/PathwayBrowser/#/R-GGA-6798745 Exocytosis of tertiary granule lumen proteins IEA Gallus gallus A0A1D5P167 R-GGA-6798749 https://reactome.org/PathwayBrowser/#/R-GGA-6798749 Exocytosis of specific granule lumen proteins IEA Gallus gallus A0A1D5P167 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5P179 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus A0A1D5P179 R-GGA-6799178 https://reactome.org/PathwayBrowser/#/R-GGA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Gallus gallus A0A1D5P179 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus A0A1D5P179 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus A0A1D5P179 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus A0A1D5P179 R-GGA-6799202 https://reactome.org/PathwayBrowser/#/R-GGA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Gallus gallus A0A1D5P181 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus A0A1D5P181 R-GGA-9865630 https://reactome.org/PathwayBrowser/#/R-GGA-9865630 Metallochaperone inserts 2Cu2+ into MT-CO2 IEA Gallus gallus A0A1D5P194 R-GGA-5624949 https://reactome.org/PathwayBrowser/#/R-GGA-5624949 Assembly of the anterograde IFT train IEA Gallus gallus A0A1D5P194 R-GGA-5625416 https://reactome.org/PathwayBrowser/#/R-GGA-5625416 Anterograde IFT IEA Gallus gallus A0A1D5P194 R-GGA-5625426 https://reactome.org/PathwayBrowser/#/R-GGA-5625426 Retrograde IFT IEA Gallus gallus A0A1D5P198 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5P198 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5P198 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5P198 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5P198 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5P198 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus A0A1D5P198 R-GGA-5624949 https://reactome.org/PathwayBrowser/#/R-GGA-5624949 Assembly of the anterograde IFT train IEA Gallus gallus A0A1D5P198 R-GGA-5625416 https://reactome.org/PathwayBrowser/#/R-GGA-5625416 Anterograde IFT IEA Gallus gallus A0A1D5P198 R-GGA-5625426 https://reactome.org/PathwayBrowser/#/R-GGA-5625426 Retrograde IFT IEA Gallus gallus A0A1D5P198 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1D5P198 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5P198 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5P198 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5P198 R-GGA-8849350 https://reactome.org/PathwayBrowser/#/R-GGA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Gallus gallus A0A1D5P198 R-GGA-8849353 https://reactome.org/PathwayBrowser/#/R-GGA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Gallus gallus A0A1D5P198 R-GGA-9018758 https://reactome.org/PathwayBrowser/#/R-GGA-9018758 RHOH binds effectors at the plasma membrane IEA Gallus gallus A0A1D5P198 R-GGA-9646679 https://reactome.org/PathwayBrowser/#/R-GGA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Gallus gallus A0A1D5P198 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1D5P198 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus A0A1D5P1A9 R-GGA-2213240 https://reactome.org/PathwayBrowser/#/R-GGA-2213240 Reduction of disulphide bonds in MHC II antigens IEA Gallus gallus A0A1D5P1C6 R-GGA-1482612 https://reactome.org/PathwayBrowser/#/R-GGA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Gallus gallus A0A1D5P1C6 R-GGA-1482685 https://reactome.org/PathwayBrowser/#/R-GGA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Gallus gallus A0A1D5P1C6 R-GGA-1482825 https://reactome.org/PathwayBrowser/#/R-GGA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Gallus gallus A0A1D5P1C6 R-GGA-1482856 https://reactome.org/PathwayBrowser/#/R-GGA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Gallus gallus A0A1D5P1C6 R-GGA-1482884 https://reactome.org/PathwayBrowser/#/R-GGA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Gallus gallus A0A1D5P1D0 R-GGA-174389 https://reactome.org/PathwayBrowser/#/R-GGA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Gallus gallus A0A1D5P1D0 R-GGA-174392 https://reactome.org/PathwayBrowser/#/R-GGA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Gallus gallus A0A1D5P1F1 R-GGA-391266 https://reactome.org/PathwayBrowser/#/R-GGA-391266 Association of CCT/TriC with sphingosine kinase 1 IEA Gallus gallus A0A1D5P1F1 R-GGA-428273 https://reactome.org/PathwayBrowser/#/R-GGA-428273 SPHK1 phosphorylates sphingoid IEA Gallus gallus A0A1D5P1F1 R-GGA-5218823 https://reactome.org/PathwayBrowser/#/R-GGA-5218823 PKC phosphorylates sphingosine kinase 1 IEA Gallus gallus A0A1D5P1F1 R-GGA-5218845 https://reactome.org/PathwayBrowser/#/R-GGA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Gallus gallus A0A1D5P1F1 R-GGA-9625814 https://reactome.org/PathwayBrowser/#/R-GGA-9625814 SPHK1 phosphorylates sphingosine in response to E2 stimulation IEA Gallus gallus A0A1D5P1F1 R-GGA-9836606 https://reactome.org/PathwayBrowser/#/R-GGA-9836606 SPHK1 binds PKR IEA Gallus gallus A0A1D5P1F1 R-GGA-9836617 https://reactome.org/PathwayBrowser/#/R-GGA-9836617 p-PKR dimer phosphorylates SPHK1 IEA Gallus gallus A0A1D5P1F1 R-GGA-9836621 https://reactome.org/PathwayBrowser/#/R-GGA-9836621 p-S225-SPHK1 localizes to cytosol IEA Gallus gallus A0A1D5P1F2 R-GGA-3257122 https://reactome.org/PathwayBrowser/#/R-GGA-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Gallus gallus A0A1D5P1F4 R-GGA-3108203 https://reactome.org/PathwayBrowser/#/R-GGA-3108203 PRC1 SUMOylates CTBP1 with SUMO2,3 IEA Gallus gallus A0A1D5P1F4 R-GGA-3108209 https://reactome.org/PathwayBrowser/#/R-GGA-3108209 PRC1 SUMOylates CTBP1 with SUMO1 IEA Gallus gallus A0A1D5P1F4 R-GGA-3229089 https://reactome.org/PathwayBrowser/#/R-GGA-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Gallus gallus A0A1D5P1F4 R-GGA-3229102 https://reactome.org/PathwayBrowser/#/R-GGA-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Gallus gallus A0A1D5P1F4 R-GGA-3927824 https://reactome.org/PathwayBrowser/#/R-GGA-3927824 PRC1 SUMOylates CASP8AP2 with SUMO1 IEA Gallus gallus A0A1D5P1F4 R-GGA-4551655 https://reactome.org/PathwayBrowser/#/R-GGA-4551655 CBX4 SUMOylates BMI1 in PRC1 with SUMO1 IEA Gallus gallus A0A1D5P1F4 R-GGA-4551727 https://reactome.org/PathwayBrowser/#/R-GGA-4551727 CBX4 SUMOylates CBX4 in PRC1 with SUMO1 IEA Gallus gallus A0A1D5P1F4 R-GGA-4570463 https://reactome.org/PathwayBrowser/#/R-GGA-4570463 CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 IEA Gallus gallus A0A1D5P1F4 R-GGA-4570499 https://reactome.org/PathwayBrowser/#/R-GGA-4570499 CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 IEA Gallus gallus A0A1D5P1F4 R-GGA-8937989 https://reactome.org/PathwayBrowser/#/R-GGA-8937989 RUNX1 binds PRC1 complexes IEA Gallus gallus A0A1D5P1F4 R-GGA-8943817 https://reactome.org/PathwayBrowser/#/R-GGA-8943817 MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter IEA Gallus gallus A0A1D5P1F4 R-GGA-9007283 https://reactome.org/PathwayBrowser/#/R-GGA-9007283 CBX3 and PRC1.6 associate with E2F6.com-1 IEA Gallus gallus A0A1D5P1F4 R-GGA-9007447 https://reactome.org/PathwayBrowser/#/R-GGA-9007447 E2F6 forms the PRC1L4 complex IEA Gallus gallus A0A1D5P1H3 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1D5P1J7 R-GGA-164832 https://reactome.org/PathwayBrowser/#/R-GGA-164832 ATPase synthesizes ATP IEA Gallus gallus A0A1D5P1J7 R-GGA-164834 https://reactome.org/PathwayBrowser/#/R-GGA-164834 Enzyme-bound ATP is released IEA Gallus gallus A0A1D5P1J7 R-GGA-164840 https://reactome.org/PathwayBrowser/#/R-GGA-164840 ADP and Pi bind to ATPase IEA Gallus gallus A0A1D5P1J7 R-GGA-8949580 https://reactome.org/PathwayBrowser/#/R-GGA-8949580 F1Fo ATP synthase dimerizes IEA Gallus gallus A0A1D5P1L0 R-GGA-372693 https://reactome.org/PathwayBrowser/#/R-GGA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Gallus gallus A0A1D5P1L0 R-GGA-372697 https://reactome.org/PathwayBrowser/#/R-GGA-372697 Crk binding to p130cas IEA Gallus gallus A0A1D5P1L0 R-GGA-372705 https://reactome.org/PathwayBrowser/#/R-GGA-372705 Recruitment of BCAR1 to PTK2 complex IEA Gallus gallus A0A1D5P1L0 R-GGA-382052 https://reactome.org/PathwayBrowser/#/R-GGA-382052 p130Cas and C3G bind PDGFR bound Crk IEA Gallus gallus A0A1D5P1L0 R-GGA-5218811 https://reactome.org/PathwayBrowser/#/R-GGA-5218811 DOCK180:ELMO binds CRK IEA Gallus gallus A0A1D5P1L0 R-GGA-5218822 https://reactome.org/PathwayBrowser/#/R-GGA-5218822 CRK binds BCAR1 and or PXN IEA Gallus gallus A0A1D5P1L0 R-GGA-5218839 https://reactome.org/PathwayBrowser/#/R-GGA-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Gallus gallus A0A1D5P1L7 R-GGA-1013012 https://reactome.org/PathwayBrowser/#/R-GGA-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Gallus gallus A0A1D5P1L7 R-GGA-1013013 https://reactome.org/PathwayBrowser/#/R-GGA-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Gallus gallus A0A1D5P1L7 R-GGA-1013020 https://reactome.org/PathwayBrowser/#/R-GGA-1013020 Activation of GIRK/Kir3 Channels IEA Gallus gallus A0A1D5P1L7 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5P1L7 R-GGA-420688 https://reactome.org/PathwayBrowser/#/R-GGA-420688 GABAB heterodimeric receptor binds GABA IEA Gallus gallus A0A1D5P1L7 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5P1L7 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5P1M1 R-GGA-1296127 https://reactome.org/PathwayBrowser/#/R-GGA-1296127 Activation of voltage gated Potassium channels IEA Gallus gallus A0A1D5P1M7 R-GGA-1592387 https://reactome.org/PathwayBrowser/#/R-GGA-1592387 Fibulin binds elastic fibres IEA Gallus gallus A0A1D5P1M7 R-GGA-2129375 https://reactome.org/PathwayBrowser/#/R-GGA-2129375 Elastin cross-linking by lysyl oxidase IEA Gallus gallus A0A1D5P1M7 R-GGA-2129385 https://reactome.org/PathwayBrowser/#/R-GGA-2129385 MFAP2, MFAP5 bind microfibrils IEA Gallus gallus A0A1D5P1M7 R-GGA-2161282 https://reactome.org/PathwayBrowser/#/R-GGA-2161282 Elastic fibres bind associated proteins IEA Gallus gallus A0A1D5P1N0 R-GGA-9861642 https://reactome.org/PathwayBrowser/#/R-GGA-9861642 NEK1 phosphorylates ME1 IEA Gallus gallus A0A1D5P1N8 R-GGA-6807557 https://reactome.org/PathwayBrowser/#/R-GGA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Gallus gallus A0A1D5P1P9 R-GGA-163090 https://reactome.org/PathwayBrowser/#/R-GGA-163090 Elongation Of The Telomeric Chromosome End IEA Gallus gallus A0A1D5P1P9 R-GGA-163099 https://reactome.org/PathwayBrowser/#/R-GGA-163099 Alignment Of The RNA Template On The Telomeric Chromosome End IEA Gallus gallus A0A1D5P1P9 R-GGA-164617 https://reactome.org/PathwayBrowser/#/R-GGA-164617 Elongation of Extended Telomeric Chromosome End IEA Gallus gallus A0A1D5P1P9 R-GGA-164620 https://reactome.org/PathwayBrowser/#/R-GGA-164620 Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End IEA Gallus gallus A0A1D5P1Q3 R-GGA-429860 https://reactome.org/PathwayBrowser/#/R-GGA-429860 DCP1-DCP2 complex decaps mRNA IEA Gallus gallus A0A1D5P1R2 R-GGA-166726 https://reactome.org/PathwayBrowser/#/R-GGA-166726 Activation of MASPs IEA Gallus gallus A0A1D5P1R2 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus A0A1D5P1R2 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus A0A1D5P1R2 R-GGA-2855054 https://reactome.org/PathwayBrowser/#/R-GGA-2855054 Ficolin-2 binds to molecular patterns on the target cell surface IEA Gallus gallus A0A1D5P1R2 R-GGA-2855125 https://reactome.org/PathwayBrowser/#/R-GGA-2855125 Ficolin-1 binds to molecular patterns on the target cell surface IEA Gallus gallus A0A1D5P1R2 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5P1R2 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5P1S9 R-GGA-432164 https://reactome.org/PathwayBrowser/#/R-GGA-432164 Ca2+ influx into the post-synaptic cell IEA Gallus gallus A0A1D5P1S9 R-GGA-438037 https://reactome.org/PathwayBrowser/#/R-GGA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5P1S9 R-GGA-451283 https://reactome.org/PathwayBrowser/#/R-GGA-451283 kainate receptor binds glutamate IEA Gallus gallus A0A1D5P1S9 R-GGA-451311 https://reactome.org/PathwayBrowser/#/R-GGA-451311 Activation of Ca-permeable Kainate receptors IEA Gallus gallus A0A1D5P1S9 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5P1S9 R-GGA-8849891 https://reactome.org/PathwayBrowser/#/R-GGA-8849891 SALMs 1-3 bind to PSD-95 family members IEA Gallus gallus A0A1D5P1T2 R-GGA-1168644 https://reactome.org/PathwayBrowser/#/R-GGA-1168644 CARMA1 recruits MALT1 and BCL10 forming CBM Complex IEA Gallus gallus A0A1D5P1T2 R-GGA-202472 https://reactome.org/PathwayBrowser/#/R-GGA-202472 Translocation of TRAF6 to CBM complex IEA Gallus gallus A0A1D5P1T2 R-GGA-202478 https://reactome.org/PathwayBrowser/#/R-GGA-202478 Interaction and oligomerization of MALT1 to Bcl10 IEA Gallus gallus A0A1D5P1T2 R-GGA-202510 https://reactome.org/PathwayBrowser/#/R-GGA-202510 Activation of TAK1-TAB2 complex IEA Gallus gallus A0A1D5P1T2 R-GGA-2730861 https://reactome.org/PathwayBrowser/#/R-GGA-2730861 Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 IEA Gallus gallus A0A1D5P1T2 R-GGA-2730864 https://reactome.org/PathwayBrowser/#/R-GGA-2730864 Recruitment of TRAF6 to CBM complex by binding to MALT1 IEA Gallus gallus A0A1D5P1T2 R-GGA-2730899 https://reactome.org/PathwayBrowser/#/R-GGA-2730899 Oligomerization of BCL10 and MALT1 IEA Gallus gallus A0A1D5P1T2 R-GGA-2730900 https://reactome.org/PathwayBrowser/#/R-GGA-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Gallus gallus A0A1D5P1T2 R-GGA-2730903 https://reactome.org/PathwayBrowser/#/R-GGA-2730903 Oligomerization of TRAF6 IEA Gallus gallus A0A1D5P1T2 R-GGA-5607732 https://reactome.org/PathwayBrowser/#/R-GGA-5607732 K63polyUb-TAK1 autophosphorylates IEA Gallus gallus A0A1D5P1T2 R-GGA-5607736 https://reactome.org/PathwayBrowser/#/R-GGA-5607736 MALT1 oligomerizes IEA Gallus gallus A0A1D5P1T2 R-GGA-5607744 https://reactome.org/PathwayBrowser/#/R-GGA-5607744 MALT1 binds BCL10 IEA Gallus gallus A0A1D5P1T2 R-GGA-5607747 https://reactome.org/PathwayBrowser/#/R-GGA-5607747 TRAF6 binds MALT1 oligomers IEA Gallus gallus A0A1D5P1T2 R-GGA-5607751 https://reactome.org/PathwayBrowser/#/R-GGA-5607751 TRAF6 oligomerizes IEA Gallus gallus A0A1D5P1T2 R-GGA-5607759 https://reactome.org/PathwayBrowser/#/R-GGA-5607759 TRIKA2 binds K63polyUb-TRAF6 oligomer IEA Gallus gallus A0A1D5P1T2 R-GGA-5660665 https://reactome.org/PathwayBrowser/#/R-GGA-5660665 Caspase-8 binds MALT IEA Gallus gallus A0A1D5P1T8 R-GGA-429955 https://reactome.org/PathwayBrowser/#/R-GGA-429955 CCR4-NOT complex deadenylates mRNA IEA Gallus gallus A0A1D5P1T8 R-GGA-6798044 https://reactome.org/PathwayBrowser/#/R-GGA-6798044 BTG2 binds CCR4-NOT complex IEA Gallus gallus A0A1D5P1U2 R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus A0A1D5P1U2 R-GGA-204169 https://reactome.org/PathwayBrowser/#/R-GGA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Gallus gallus A0A1D5P1U2 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1D5P1U2 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1D5P1U2 R-GGA-9861616 https://reactome.org/PathwayBrowser/#/R-GGA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus A0A1D5P1U2 R-GGA-9861667 https://reactome.org/PathwayBrowser/#/R-GGA-9861667 DLAT trimer transfers acetyl to CoA IEA Gallus gallus A0A1D5P1U2 R-GGA-9861734 https://reactome.org/PathwayBrowser/#/R-GGA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Gallus gallus A0A1D5P1W7 R-GGA-1655831 https://reactome.org/PathwayBrowser/#/R-GGA-1655831 SREBP1A,1C,2 translocates to the nucleus IEA Gallus gallus A0A1D5P1W7 R-GGA-2065539 https://reactome.org/PathwayBrowser/#/R-GGA-2065539 SREBP1A,1C,2:Importin beta-1 dissociates IEA Gallus gallus A0A1D5P1W7 R-GGA-2065550 https://reactome.org/PathwayBrowser/#/R-GGA-2065550 SREBP1A,1C,2 binds Importin beta-1 IEA Gallus gallus A0A1D5P1W7 R-GGA-211191 https://reactome.org/PathwayBrowser/#/R-GGA-211191 Association of DFF with alpha:beta importin IEA Gallus gallus A0A1D5P1W7 R-GGA-211206 https://reactome.org/PathwayBrowser/#/R-GGA-211206 Translocation of DFF to the nucleus IEA Gallus gallus A0A1D5P1W7 R-GGA-6798749 https://reactome.org/PathwayBrowser/#/R-GGA-6798749 Exocytosis of specific granule lumen proteins IEA Gallus gallus A0A1D5P1W7 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5P1W7 R-GGA-9029667 https://reactome.org/PathwayBrowser/#/R-GGA-9029667 DFF dissociates from importin-alpha:importin-beta IEA Gallus gallus A0A1D5P1W7 R-GGA-913529 https://reactome.org/PathwayBrowser/#/R-GGA-913529 Translocation of p-STAT1:p-STAT1 dimer to nucleus IEA Gallus gallus A0A1D5P1W7 R-GGA-9624798 https://reactome.org/PathwayBrowser/#/R-GGA-9624798 LBR binds KPNB1 IEA Gallus gallus A0A1D5P1W7 R-GGA-9710963 https://reactome.org/PathwayBrowser/#/R-GGA-9710963 p-STAT1dimer:KPNA1 binds KPNB1 IEA Gallus gallus A0A1D5P1W7 R-GGA-9734670 https://reactome.org/PathwayBrowser/#/R-GGA-9734670 ORC6 binds KPNA1 or KPNA6 IEA Gallus gallus A0A1D5P1W7 R-GGA-9734687 https://reactome.org/PathwayBrowser/#/R-GGA-9734687 ORC6 is phosphorylated on T195 IEA Gallus gallus A0A1D5P1W7 R-GGA-9734713 https://reactome.org/PathwayBrowser/#/R-GGA-9734713 ORC6 translocates to the nucleus IEA Gallus gallus A0A1D5P1Y9 R-GGA-1222516 https://reactome.org/PathwayBrowser/#/R-GGA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Gallus gallus A0A1D5P1Y9 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1D5P1Y9 R-GGA-74723 https://reactome.org/PathwayBrowser/#/R-GGA-74723 Endosome acidification IEA Gallus gallus A0A1D5P1Y9 R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus A0A1D5P1Y9 R-GGA-9639286 https://reactome.org/PathwayBrowser/#/R-GGA-9639286 RRAGC,D exchanges GTP for GDP IEA Gallus gallus A0A1D5P1Y9 R-GGA-9640167 https://reactome.org/PathwayBrowser/#/R-GGA-9640167 RRAGA,B exchanges GDP for GTP IEA Gallus gallus A0A1D5P1Y9 R-GGA-9640168 https://reactome.org/PathwayBrowser/#/R-GGA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Gallus gallus A0A1D5P1Y9 R-GGA-9640175 https://reactome.org/PathwayBrowser/#/R-GGA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Gallus gallus A0A1D5P1Y9 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus A0A1D5P1Y9 R-GGA-9645598 https://reactome.org/PathwayBrowser/#/R-GGA-9645598 RRAGC,D hydrolyzes GTP IEA Gallus gallus A0A1D5P1Y9 R-GGA-9645608 https://reactome.org/PathwayBrowser/#/R-GGA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Gallus gallus A0A1D5P1Y9 R-GGA-9646468 https://reactome.org/PathwayBrowser/#/R-GGA-9646468 mTORC1 binds RHEB:GTP IEA Gallus gallus A0A1D5P203 R-GGA-9630967 https://reactome.org/PathwayBrowser/#/R-GGA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Gallus gallus A0A1D5P206 R-GGA-2028583 https://reactome.org/PathwayBrowser/#/R-GGA-2028583 Phosphorylation of YAP by LATS2 IEA Gallus gallus A0A1D5P206 R-GGA-2028661 https://reactome.org/PathwayBrowser/#/R-GGA-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Gallus gallus A0A1D5P206 R-GGA-2028724 https://reactome.org/PathwayBrowser/#/R-GGA-2028724 AMOT proteins bind YAP1 IEA Gallus gallus A0A1D5P206 R-GGA-2028735 https://reactome.org/PathwayBrowser/#/R-GGA-2028735 AMOT proteins bind WWTR1 (TAZ) IEA Gallus gallus A0A1D5P223 R-GGA-2730837 https://reactome.org/PathwayBrowser/#/R-GGA-2730837 Recruitment of GRB2:SOS to p-10Y-NTAL IEA Gallus gallus A0A1D5P223 R-GGA-2730842 https://reactome.org/PathwayBrowser/#/R-GGA-2730842 PI3K associates with phosphorylated GAB2 IEA Gallus gallus A0A1D5P223 R-GGA-2730870 https://reactome.org/PathwayBrowser/#/R-GGA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Gallus gallus A0A1D5P248 R-GGA-2684901 https://reactome.org/PathwayBrowser/#/R-GGA-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Gallus gallus A0A1D5P248 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5P263 R-GGA-203613 https://reactome.org/PathwayBrowser/#/R-GGA-203613 Depalmitoylation of eNOS IEA Gallus gallus A0A1D5P263 R-GGA-9647991 https://reactome.org/PathwayBrowser/#/R-GGA-9647991 Palmostatin B binds RAS depalmitoylases IEA Gallus gallus A0A1D5P263 R-GGA-9647994 https://reactome.org/PathwayBrowser/#/R-GGA-9647994 RAS proteins are depalmitoylated IEA Gallus gallus A0A1D5P266 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5P266 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5P266 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5P266 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5P266 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5P266 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P266 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P266 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5P266 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5P276 R-GGA-193656 https://reactome.org/PathwayBrowser/#/R-GGA-193656 p75NTR interacts with RIP2 IEA Gallus gallus A0A1D5P276 R-GGA-202459 https://reactome.org/PathwayBrowser/#/R-GGA-202459 Phosphorylation of Bcl10 IEA Gallus gallus A0A1D5P280 R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus A0A1D5P280 R-GGA-9621179 https://reactome.org/PathwayBrowser/#/R-GGA-9621179 Cinaciguat binds sGC:NO IEA Gallus gallus A0A1D5P287 R-GGA-445699 https://reactome.org/PathwayBrowser/#/R-GGA-445699 ATP Hydrolysis By Myosin IEA Gallus gallus A0A1D5P287 R-GGA-445700 https://reactome.org/PathwayBrowser/#/R-GGA-445700 Myosin Binds ATP IEA Gallus gallus A0A1D5P287 R-GGA-445704 https://reactome.org/PathwayBrowser/#/R-GGA-445704 Calcium Binds Caldesmon IEA Gallus gallus A0A1D5P287 R-GGA-445705 https://reactome.org/PathwayBrowser/#/R-GGA-445705 Release Of ADP From Myosin IEA Gallus gallus A0A1D5P287 R-GGA-5668932 https://reactome.org/PathwayBrowser/#/R-GGA-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Gallus gallus A0A1D5P2A2 R-GGA-3321883 https://reactome.org/PathwayBrowser/#/R-GGA-3321883 MSL acetylates histone H4 IEA Gallus gallus A0A1D5P2A3 R-GGA-5624953 https://reactome.org/PathwayBrowser/#/R-GGA-5624953 ARL13B binds INPP5E IEA Gallus gallus A0A1D5P2A3 R-GGA-5624954 https://reactome.org/PathwayBrowser/#/R-GGA-5624954 INPP5E translocates to the primary cilium IEA Gallus gallus A0A1D5P2A3 R-GGA-5624956 https://reactome.org/PathwayBrowser/#/R-GGA-5624956 PDE6D binds INPP5E IEA Gallus gallus A0A1D5P2A3 R-GGA-5638012 https://reactome.org/PathwayBrowser/#/R-GGA-5638012 PDE6D dissociates from ARL13B:INPP5E IEA Gallus gallus A0A1D5P2A3 R-GGA-9654525 https://reactome.org/PathwayBrowser/#/R-GGA-9654525 PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ IEA Gallus gallus A0A1D5P2B5 R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus A0A1D5P2B5 R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus A0A1D5P2B5 R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus A0A1D5P2B5 R-GGA-194187 https://reactome.org/PathwayBrowser/#/R-GGA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Gallus gallus A0A1D5P2B5 R-GGA-200406 https://reactome.org/PathwayBrowser/#/R-GGA-200406 CPT1A transfers PALM to CAR IEA Gallus gallus A0A1D5P2B5 R-GGA-376419 https://reactome.org/PathwayBrowser/#/R-GGA-376419 Formation of NR-MED1 Coactivator Complex IEA Gallus gallus A0A1D5P2B5 R-GGA-381262 https://reactome.org/PathwayBrowser/#/R-GGA-381262 Formation of PPARG:RXRA heterodimer (ARF6 complex) IEA Gallus gallus A0A1D5P2B5 R-GGA-382096 https://reactome.org/PathwayBrowser/#/R-GGA-382096 Formation of NR-NCOR Corepressor Complex IEA Gallus gallus A0A1D5P2B5 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus A0A1D5P2B5 R-GGA-400183 https://reactome.org/PathwayBrowser/#/R-GGA-400183 PPARA:RXRA binds Corepressors of PPARA IEA Gallus gallus A0A1D5P2B5 R-GGA-400204 https://reactome.org/PathwayBrowser/#/R-GGA-400204 PPARA binds RXRA IEA Gallus gallus A0A1D5P2B5 R-GGA-4341048 https://reactome.org/PathwayBrowser/#/R-GGA-4341048 SUMOylation of RXRA with SUMO1 IEA Gallus gallus A0A1D5P2B5 R-GGA-5334854 https://reactome.org/PathwayBrowser/#/R-GGA-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Gallus gallus A0A1D5P2B5 R-GGA-5340251 https://reactome.org/PathwayBrowser/#/R-GGA-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Gallus gallus A0A1D5P2B5 R-GGA-5422942 https://reactome.org/PathwayBrowser/#/R-GGA-5422942 RXRA:PPARD binds FABP5:atRA IEA Gallus gallus A0A1D5P2B5 R-GGA-5634100 https://reactome.org/PathwayBrowser/#/R-GGA-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Gallus gallus A0A1D5P2B5 R-GGA-5634103 https://reactome.org/PathwayBrowser/#/R-GGA-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Gallus gallus A0A1D5P2B5 R-GGA-9009817 https://reactome.org/PathwayBrowser/#/R-GGA-9009817 Acitretin binds to RAR:RXR IEA Gallus gallus A0A1D5P2B5 R-GGA-9617067 https://reactome.org/PathwayBrowser/#/R-GGA-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Gallus gallus A0A1D5P2B5 R-GGA-9732629 https://reactome.org/PathwayBrowser/#/R-GGA-9732629 PPARG binds PPARG agonists IEA Gallus gallus A0A1D5P2B5 R-GGA-9734475 https://reactome.org/PathwayBrowser/#/R-GGA-9734475 PPARA binds fibrates IEA Gallus gallus A0A1D5P2B5 R-GGA-9843115 https://reactome.org/PathwayBrowser/#/R-GGA-9843115 Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci IEA Gallus gallus A0A1D5P2B5 R-GGA-9843117 https://reactome.org/PathwayBrowser/#/R-GGA-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1D5P2B5 R-GGA-9843118 https://reactome.org/PathwayBrowser/#/R-GGA-9843118 RXRA binds ligands IEA Gallus gallus A0A1D5P2B5 R-GGA-9843120 https://reactome.org/PathwayBrowser/#/R-GGA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1D5P2C0 R-GGA-177934 https://reactome.org/PathwayBrowser/#/R-GGA-177934 EGFR autophosphorylation IEA Gallus gallus A0A1D5P2C0 R-GGA-9851407 https://reactome.org/PathwayBrowser/#/R-GGA-9851407 FAM83B, (FAM83A, FAM83D) bind EGFR IEA Gallus gallus A0A1D5P2C6 R-GGA-162730 https://reactome.org/PathwayBrowser/#/R-GGA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Gallus gallus A0A1D5P2D1 R-GGA-2997616 https://reactome.org/PathwayBrowser/#/R-GGA-2997616 PIAS1,4 SUMOylates BRCA1 with SUMO2,3 IEA Gallus gallus A0A1D5P2D1 R-GGA-2997709 https://reactome.org/PathwayBrowser/#/R-GGA-2997709 PIAS1,4 SUMOylates BRCA1 with SUMO1 IEA Gallus gallus A0A1D5P2D1 R-GGA-2997723 https://reactome.org/PathwayBrowser/#/R-GGA-2997723 PIAS4 SUMOylates TP53BP1 with SUMO1 IEA Gallus gallus A0A1D5P2D1 R-GGA-3465545 https://reactome.org/PathwayBrowser/#/R-GGA-3465545 PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 IEA Gallus gallus A0A1D5P2D1 R-GGA-3968362 https://reactome.org/PathwayBrowser/#/R-GGA-3968362 SUMOylation of PIAS4 with SUMO1 IEA Gallus gallus A0A1D5P2D1 R-GGA-4341070 https://reactome.org/PathwayBrowser/#/R-GGA-4341070 PIAS4 SUMOylates PPARA with SUMO1 IEA Gallus gallus A0A1D5P2D1 R-GGA-4546387 https://reactome.org/PathwayBrowser/#/R-GGA-4546387 PIAS4 SUMOylates VDR with SUMO2 IEA Gallus gallus A0A1D5P2D1 R-GGA-4551604 https://reactome.org/PathwayBrowser/#/R-GGA-4551604 PIAS4 SUMOylates PARP1 with SUMO1 IEA Gallus gallus A0A1D5P2D1 R-GGA-4551661 https://reactome.org/PathwayBrowser/#/R-GGA-4551661 PIAS4 SUMOylates RNF168 with SUMO1 IEA Gallus gallus A0A1D5P2D1 R-GGA-4551721 https://reactome.org/PathwayBrowser/#/R-GGA-4551721 PIAS4 SUMOylates VHL with SUMO1 IEA Gallus gallus A0A1D5P2D1 R-GGA-4551724 https://reactome.org/PathwayBrowser/#/R-GGA-4551724 PIAS4 SUMOylates HERC2 with SUMO1 IEA Gallus gallus A0A1D5P2D1 R-GGA-4551768 https://reactome.org/PathwayBrowser/#/R-GGA-4551768 PIAS4 SUMOylates PARP1 with SUMO2,3 IEA Gallus gallus A0A1D5P2D1 R-GGA-4641350 https://reactome.org/PathwayBrowser/#/R-GGA-4641350 PIAS4 SUMOylates TOP2A with SUMO2,3 IEA Gallus gallus A0A1D5P2D1 R-GGA-4719413 https://reactome.org/PathwayBrowser/#/R-GGA-4719413 PIAS2,3,4 SUMOylate RORA with SUMO2 IEA Gallus gallus A0A1D5P2D1 R-GGA-4719436 https://reactome.org/PathwayBrowser/#/R-GGA-4719436 PIAS2,3,4 SUMOylate RORA with SUMO1 IEA Gallus gallus A0A1D5P2D1 R-GGA-5228521 https://reactome.org/PathwayBrowser/#/R-GGA-5228521 PIAS1,4 SUMOylate CASP8AP2 with SUMO1 IEA Gallus gallus A0A1D5P2D1 R-GGA-5682586 https://reactome.org/PathwayBrowser/#/R-GGA-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Gallus gallus A0A1D5P2D1 R-GGA-5682598 https://reactome.org/PathwayBrowser/#/R-GGA-5682598 ATM phosphorylates HERC2 IEA Gallus gallus A0A1D5P2D1 R-GGA-5682607 https://reactome.org/PathwayBrowser/#/R-GGA-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Gallus gallus A0A1D5P2D1 R-GGA-5682629 https://reactome.org/PathwayBrowser/#/R-GGA-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Gallus gallus A0A1D5P2D1 R-GGA-5682858 https://reactome.org/PathwayBrowser/#/R-GGA-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Gallus gallus A0A1D5P2D1 R-GGA-5682863 https://reactome.org/PathwayBrowser/#/R-GGA-5682863 RNF168 binds DNA DSBs IEA Gallus gallus A0A1D5P2D1 R-GGA-5683077 https://reactome.org/PathwayBrowser/#/R-GGA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Gallus gallus A0A1D5P2D1 R-GGA-5683384 https://reactome.org/PathwayBrowser/#/R-GGA-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Gallus gallus A0A1D5P2D1 R-GGA-5683385 https://reactome.org/PathwayBrowser/#/R-GGA-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Gallus gallus A0A1D5P2D1 R-GGA-5683425 https://reactome.org/PathwayBrowser/#/R-GGA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Gallus gallus A0A1D5P2D1 R-GGA-5683735 https://reactome.org/PathwayBrowser/#/R-GGA-5683735 CHEK2 is recruited to DNA DSBs IEA Gallus gallus A0A1D5P2D1 R-GGA-5683801 https://reactome.org/PathwayBrowser/#/R-GGA-5683801 CHEK2 phosphorylates BRCA1 IEA Gallus gallus A0A1D5P2D1 R-GGA-5684052 https://reactome.org/PathwayBrowser/#/R-GGA-5684052 PIAS4 SUMOylates MDC1 IEA Gallus gallus A0A1D5P2D1 R-GGA-5686685 https://reactome.org/PathwayBrowser/#/R-GGA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Gallus gallus A0A1D5P2D1 R-GGA-5686704 https://reactome.org/PathwayBrowser/#/R-GGA-5686704 Activated ATM phosphorylates DCLRE1C IEA Gallus gallus A0A1D5P2D1 R-GGA-5686900 https://reactome.org/PathwayBrowser/#/R-GGA-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Gallus gallus A0A1D5P2D1 R-GGA-5693551 https://reactome.org/PathwayBrowser/#/R-GGA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Gallus gallus A0A1D5P2D1 R-GGA-5693566 https://reactome.org/PathwayBrowser/#/R-GGA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Gallus gallus A0A1D5P2D1 R-GGA-69891 https://reactome.org/PathwayBrowser/#/R-GGA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Gallus gallus A0A1D5P2D5 R-GGA-9825759 https://reactome.org/PathwayBrowser/#/R-GGA-9825759 MAPK-dependent phosphorylation of KARS IEA Gallus gallus A0A1D5P2D9 R-GGA-391266 https://reactome.org/PathwayBrowser/#/R-GGA-391266 Association of CCT/TriC with sphingosine kinase 1 IEA Gallus gallus A0A1D5P2D9 R-GGA-6814119 https://reactome.org/PathwayBrowser/#/R-GGA-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Gallus gallus A0A1D5P2D9 R-GGA-6814120 https://reactome.org/PathwayBrowser/#/R-GGA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Gallus gallus A0A1D5P2D9 R-GGA-6814121 https://reactome.org/PathwayBrowser/#/R-GGA-6814121 PDCL binds G-protein beta and TRiC/CCT IEA Gallus gallus A0A1D5P2D9 R-GGA-6814124 https://reactome.org/PathwayBrowser/#/R-GGA-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Gallus gallus A0A1D5P2D9 R-GGA-8850527 https://reactome.org/PathwayBrowser/#/R-GGA-8850527 PDCL releases folded G-beta from TRiC/CCT IEA Gallus gallus A0A1D5P2D9 R-GGA-8850529 https://reactome.org/PathwayBrowser/#/R-GGA-8850529 RGS proteins bind GNB5 and CCT/TRiC IEA Gallus gallus A0A1D5P2D9 R-GGA-8850534 https://reactome.org/PathwayBrowser/#/R-GGA-8850534 PDCL promotes G-protein beta 5 folding IEA Gallus gallus A0A1D5P2D9 R-GGA-8850539 https://reactome.org/PathwayBrowser/#/R-GGA-8850539 Release of GNB5:RGS dimers from CCT/TRiC IEA Gallus gallus A0A1D5P2E6 R-GGA-6805546 https://reactome.org/PathwayBrowser/#/R-GGA-6805546 Keratin type I binds keratin type II IEA Gallus gallus A0A1D5P2E6 R-GGA-6805573 https://reactome.org/PathwayBrowser/#/R-GGA-6805573 Keratin type I/type II heterodimers form tetramers IEA Gallus gallus A0A1D5P2E6 R-GGA-6806610 https://reactome.org/PathwayBrowser/#/R-GGA-6806610 Keratin filament formation IEA Gallus gallus A0A1D5P2E6 R-GGA-6806613 https://reactome.org/PathwayBrowser/#/R-GGA-6806613 Keratin tetramers bind to form unit length filaments IEA Gallus gallus A0A1D5P2E6 R-GGA-6806629 https://reactome.org/PathwayBrowser/#/R-GGA-6806629 Formation of tonofilament bundles IEA Gallus gallus A0A1D5P2E6 R-GGA-6809393 https://reactome.org/PathwayBrowser/#/R-GGA-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Gallus gallus A0A1D5P2E6 R-GGA-6810357 https://reactome.org/PathwayBrowser/#/R-GGA-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Gallus gallus A0A1D5P2F2 R-GGA-109699 https://reactome.org/PathwayBrowser/#/R-GGA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Gallus gallus A0A1D5P2F2 R-GGA-190245 https://reactome.org/PathwayBrowser/#/R-GGA-190245 FGFR1b binds to FGF IEA Gallus gallus A0A1D5P2F2 R-GGA-190260 https://reactome.org/PathwayBrowser/#/R-GGA-190260 FGFR2b binds to FGF IEA Gallus gallus A0A1D5P2F2 R-GGA-190408 https://reactome.org/PathwayBrowser/#/R-GGA-190408 Autocatalytic phosphorylation of FGFR2b IEA Gallus gallus A0A1D5P2F2 R-GGA-190427 https://reactome.org/PathwayBrowser/#/R-GGA-190427 Autocatalytic phosphorylation of FGFR1b IEA Gallus gallus A0A1D5P2F2 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654147 https://reactome.org/PathwayBrowser/#/R-GGA-5654147 Activated FGFR2 phosphorylates PLCG1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654149 https://reactome.org/PathwayBrowser/#/R-GGA-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654157 https://reactome.org/PathwayBrowser/#/R-GGA-5654157 p-4Y-PLCG1 dissociates from activated FGFR2 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654159 https://reactome.org/PathwayBrowser/#/R-GGA-5654159 Activated FGFR2 binds PLCG1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654165 https://reactome.org/PathwayBrowser/#/R-GGA-5654165 p-4Y-PLCG1 dissociates from activated FGFR1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654167 https://reactome.org/PathwayBrowser/#/R-GGA-5654167 Activated FGFR1 binds PLCG1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654392 https://reactome.org/PathwayBrowser/#/R-GGA-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5P2F2 R-GGA-5654397 https://reactome.org/PathwayBrowser/#/R-GGA-5654397 Activated FGFR2 phosphorylates FRS2 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654399 https://reactome.org/PathwayBrowser/#/R-GGA-5654399 Activated FGFR2 binds FRS2 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654402 https://reactome.org/PathwayBrowser/#/R-GGA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5P2F2 R-GGA-5654404 https://reactome.org/PathwayBrowser/#/R-GGA-5654404 Activated FGFR2 binds SHC1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654406 https://reactome.org/PathwayBrowser/#/R-GGA-5654406 Activated FGFR2:p-SHC1 binds GRB2:SOS1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654407 https://reactome.org/PathwayBrowser/#/R-GGA-5654407 Activated FGFR2 phosphorylates SHC1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654511 https://reactome.org/PathwayBrowser/#/R-GGA-5654511 FGFRL1 dimer binds FGFs IEA Gallus gallus A0A1D5P2F2 R-GGA-5654560 https://reactome.org/PathwayBrowser/#/R-GGA-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654562 https://reactome.org/PathwayBrowser/#/R-GGA-5654562 Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654569 https://reactome.org/PathwayBrowser/#/R-GGA-5654569 Activated FGFR1 binds FRS2 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654571 https://reactome.org/PathwayBrowser/#/R-GGA-5654571 Activated FGFR1 binds FRS3 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654573 https://reactome.org/PathwayBrowser/#/R-GGA-5654573 Activated FGFR1 binds SHC1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654575 https://reactome.org/PathwayBrowser/#/R-GGA-5654575 Activated FGFR1 phosphorylates FRS2 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654578 https://reactome.org/PathwayBrowser/#/R-GGA-5654578 Activated FGFR1 phosphorylates FRS3 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654582 https://reactome.org/PathwayBrowser/#/R-GGA-5654582 Activated FGFR1 phosphorylates SHC1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654584 https://reactome.org/PathwayBrowser/#/R-GGA-5654584 Activated FGFR1:p-FRS bind to PPTN11 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654586 https://reactome.org/PathwayBrowser/#/R-GGA-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654587 https://reactome.org/PathwayBrowser/#/R-GGA-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654591 https://reactome.org/PathwayBrowser/#/R-GGA-5654591 Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Gallus gallus A0A1D5P2F2 R-GGA-5654592 https://reactome.org/PathwayBrowser/#/R-GGA-5654592 Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654594 https://reactome.org/PathwayBrowser/#/R-GGA-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654596 https://reactome.org/PathwayBrowser/#/R-GGA-5654596 Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Gallus gallus A0A1D5P2F2 R-GGA-5654597 https://reactome.org/PathwayBrowser/#/R-GGA-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654600 https://reactome.org/PathwayBrowser/#/R-GGA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5P2F2 R-GGA-5654603 https://reactome.org/PathwayBrowser/#/R-GGA-5654603 Activated FGFR2 binds FRS3 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654605 https://reactome.org/PathwayBrowser/#/R-GGA-5654605 Activated FGFR2 phosphorylates FRS3 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654607 https://reactome.org/PathwayBrowser/#/R-GGA-5654607 Activated FGFR2 phosphorylates PPTN11 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654608 https://reactome.org/PathwayBrowser/#/R-GGA-5654608 Activated FGFR2:p-FRS bind to PPTN11 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654612 https://reactome.org/PathwayBrowser/#/R-GGA-5654612 Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654614 https://reactome.org/PathwayBrowser/#/R-GGA-5654614 Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Gallus gallus A0A1D5P2F2 R-GGA-5654615 https://reactome.org/PathwayBrowser/#/R-GGA-5654615 Activated FGFR2:pFRS binds GRB2:SOS1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654618 https://reactome.org/PathwayBrowser/#/R-GGA-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5P2F2 R-GGA-5654620 https://reactome.org/PathwayBrowser/#/R-GGA-5654620 Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654622 https://reactome.org/PathwayBrowser/#/R-GGA-5654622 Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Gallus gallus A0A1D5P2F2 R-GGA-5654672 https://reactome.org/PathwayBrowser/#/R-GGA-5654672 CBL ubiquitinates FRS2 and FGFR1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654673 https://reactome.org/PathwayBrowser/#/R-GGA-5654673 p-CBL:GRB2 binds p-FRS2:activated FGFR1 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654677 https://reactome.org/PathwayBrowser/#/R-GGA-5654677 CBL ubiquitinates FRS2 and FGFR2 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654690 https://reactome.org/PathwayBrowser/#/R-GGA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654692 https://reactome.org/PathwayBrowser/#/R-GGA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654697 https://reactome.org/PathwayBrowser/#/R-GGA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654701 https://reactome.org/PathwayBrowser/#/R-GGA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5P2F2 R-GGA-5654729 https://reactome.org/PathwayBrowser/#/R-GGA-5654729 p-CBL:GRB2 binds p-FRS2:activated FGFR2 IEA Gallus gallus A0A1D5P2F2 R-GGA-5656064 https://reactome.org/PathwayBrowser/#/R-GGA-5656064 Activated FGFR1 binds FLRT1,2,3 IEA Gallus gallus A0A1D5P2F2 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5P2F2 R-GGA-8941618 https://reactome.org/PathwayBrowser/#/R-GGA-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5P2F2 R-GGA-8941623 https://reactome.org/PathwayBrowser/#/R-GGA-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5P2G3 R-GGA-1483004 https://reactome.org/PathwayBrowser/#/R-GGA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Gallus gallus A0A1D5P2G3 R-GGA-1483222 https://reactome.org/PathwayBrowser/#/R-GGA-1483222 ETA is phosphorylated to PETA by CHK/ETNK IEA Gallus gallus A0A1D5P2H8 R-GGA-481007 https://reactome.org/PathwayBrowser/#/R-GGA-481007 Exocytosis of platelet alpha granule contents IEA Gallus gallus A0A1D5P2H9 R-GGA-622326 https://reactome.org/PathwayBrowser/#/R-GGA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Gallus gallus A0A1D5P2H9 R-GGA-629595 https://reactome.org/PathwayBrowser/#/R-GGA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Gallus gallus A0A1D5P2H9 R-GGA-629596 https://reactome.org/PathwayBrowser/#/R-GGA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Gallus gallus A0A1D5P2H9 R-GGA-629599 https://reactome.org/PathwayBrowser/#/R-GGA-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Gallus gallus A0A1D5P2J1 R-GGA-8864343 https://reactome.org/PathwayBrowser/#/R-GGA-8864343 KCTD1 binds TFAP2 homo- and heterodimers IEA Gallus gallus A0A1D5P2K1 R-GGA-5688786 https://reactome.org/PathwayBrowser/#/R-GGA-5688786 ATXN3 binds RAD23 IEA Gallus gallus A0A1D5P2K1 R-GGA-5689861 https://reactome.org/PathwayBrowser/#/R-GGA-5689861 Recruitment of XPA and release of CAK IEA Gallus gallus A0A1D5P2K1 R-GGA-5690996 https://reactome.org/PathwayBrowser/#/R-GGA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Gallus gallus A0A1D5P2K1 R-GGA-5691000 https://reactome.org/PathwayBrowser/#/R-GGA-5691000 TFIIH binds GG-NER site to form a verification complex IEA Gallus gallus A0A1D5P2K1 R-GGA-5691004 https://reactome.org/PathwayBrowser/#/R-GGA-5691004 XPC binds RAD23 and CETN2 IEA Gallus gallus A0A1D5P2K1 R-GGA-5691006 https://reactome.org/PathwayBrowser/#/R-GGA-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Gallus gallus A0A1D5P2K1 R-GGA-5696655 https://reactome.org/PathwayBrowser/#/R-GGA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Gallus gallus A0A1D5P2K1 R-GGA-5696664 https://reactome.org/PathwayBrowser/#/R-GGA-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Gallus gallus A0A1D5P2K1 R-GGA-5696670 https://reactome.org/PathwayBrowser/#/R-GGA-5696670 CHD1L is recruited to GG-NER site IEA Gallus gallus A0A1D5P2K1 R-GGA-6782943 https://reactome.org/PathwayBrowser/#/R-GGA-6782943 UV-DDB ubiquitinates XPC IEA Gallus gallus A0A1D5P2K1 R-GGA-6790454 https://reactome.org/PathwayBrowser/#/R-GGA-6790454 SUMOylation of XPC IEA Gallus gallus A0A1D5P2K1 R-GGA-6790487 https://reactome.org/PathwayBrowser/#/R-GGA-6790487 RNF111 ubiquitinates SUMOylated XPC IEA Gallus gallus A0A1D5P2K7 R-GGA-212380 https://reactome.org/PathwayBrowser/#/R-GGA-212380 Formation of TRAP coactivator complex IEA Gallus gallus A0A1D5P2K7 R-GGA-212432 https://reactome.org/PathwayBrowser/#/R-GGA-212432 Formation of DRIP coactivator complex IEA Gallus gallus A0A1D5P2K7 R-GGA-9843120 https://reactome.org/PathwayBrowser/#/R-GGA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1D5P2L3 R-GGA-1168642 https://reactome.org/PathwayBrowser/#/R-GGA-1168642 SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB IEA Gallus gallus A0A1D5P2L3 R-GGA-1168643 https://reactome.org/PathwayBrowser/#/R-GGA-1168643 SCF-beta-TrCP ubiquitinylates IkB IEA Gallus gallus A0A1D5P2L3 R-GGA-1170539 https://reactome.org/PathwayBrowser/#/R-GGA-1170539 Prolactin receptor is internalized IEA Gallus gallus A0A1D5P2L3 R-GGA-1363328 https://reactome.org/PathwayBrowser/#/R-GGA-1363328 Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex IEA Gallus gallus A0A1D5P2L3 R-GGA-1363331 https://reactome.org/PathwayBrowser/#/R-GGA-1363331 Ubiquitination of p130 (RBL2) by SCF (Skp2) IEA Gallus gallus A0A1D5P2L3 R-GGA-1370500 https://reactome.org/PathwayBrowser/#/R-GGA-1370500 PRLR binds SCF beta-TrCP complex IEA Gallus gallus A0A1D5P2L3 R-GGA-174159 https://reactome.org/PathwayBrowser/#/R-GGA-174159 Ubiquitination of Emi1 by SCF-beta-TrCP IEA Gallus gallus A0A1D5P2L3 R-GGA-187545 https://reactome.org/PathwayBrowser/#/R-GGA-187545 Association of Cks1 with SCF(Skp2) complex IEA Gallus gallus A0A1D5P2L3 R-GGA-187552 https://reactome.org/PathwayBrowser/#/R-GGA-187552 Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex IEA Gallus gallus A0A1D5P2L3 R-GGA-187574 https://reactome.org/PathwayBrowser/#/R-GGA-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Gallus gallus A0A1D5P2L3 R-GGA-187575 https://reactome.org/PathwayBrowser/#/R-GGA-187575 Ubiquitination of phospho-p27/p21 IEA Gallus gallus A0A1D5P2L3 R-GGA-209063 https://reactome.org/PathwayBrowser/#/R-GGA-209063 Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex IEA Gallus gallus A0A1D5P2L3 R-GGA-209125 https://reactome.org/PathwayBrowser/#/R-GGA-209125 SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex IEA Gallus gallus A0A1D5P2L3 R-GGA-2130279 https://reactome.org/PathwayBrowser/#/R-GGA-2130279 Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex IEA Gallus gallus A0A1D5P2L3 R-GGA-2130282 https://reactome.org/PathwayBrowser/#/R-GGA-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Gallus gallus A0A1D5P2L3 R-GGA-2130286 https://reactome.org/PathwayBrowser/#/R-GGA-2130286 Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) IEA Gallus gallus A0A1D5P2L3 R-GGA-3000335 https://reactome.org/PathwayBrowser/#/R-GGA-3000335 SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA IEA Gallus gallus A0A1D5P2L3 R-GGA-3000339 https://reactome.org/PathwayBrowser/#/R-GGA-3000339 Phosphorylated BORA binds SCF-beta-TrCp1/2 IEA Gallus gallus A0A1D5P2L3 R-GGA-5607723 https://reactome.org/PathwayBrowser/#/R-GGA-5607723 SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB IEA Gallus gallus A0A1D5P2L3 R-GGA-5607728 https://reactome.org/PathwayBrowser/#/R-GGA-5607728 beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex IEA Gallus gallus A0A1D5P2L3 R-GGA-5610742 https://reactome.org/PathwayBrowser/#/R-GGA-5610742 SCF(beta-TrCP) ubiquitinates p-GLI1 IEA Gallus gallus A0A1D5P2L3 R-GGA-5610746 https://reactome.org/PathwayBrowser/#/R-GGA-5610746 SCF(beta-TrCP) ubiquitinates p-GLI3 IEA Gallus gallus A0A1D5P2L3 R-GGA-5684248 https://reactome.org/PathwayBrowser/#/R-GGA-5684248 SCF betaTrCP1,2 binds p-NFkB p105:TPL2:ABIN2 IEA Gallus gallus A0A1D5P2L3 R-GGA-5684250 https://reactome.org/PathwayBrowser/#/R-GGA-5684250 SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 IEA Gallus gallus A0A1D5P2L3 R-GGA-5691108 https://reactome.org/PathwayBrowser/#/R-GGA-5691108 SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 IEA Gallus gallus A0A1D5P2L3 R-GGA-5691131 https://reactome.org/PathwayBrowser/#/R-GGA-5691131 CANDI binds CUL1 IEA Gallus gallus A0A1D5P2L3 R-GGA-5691167 https://reactome.org/PathwayBrowser/#/R-GGA-5691167 CUL1, SKP1, FBXL5 bind IEA Gallus gallus A0A1D5P2L3 R-GGA-5691176 https://reactome.org/PathwayBrowser/#/R-GGA-5691176 NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) IEA Gallus gallus A0A1D5P2L3 R-GGA-68946 https://reactome.org/PathwayBrowser/#/R-GGA-68946 Phosphorylated Orc1 is ubiquitinated while still associated with chromatin IEA Gallus gallus A0A1D5P2L3 R-GGA-8853496 https://reactome.org/PathwayBrowser/#/R-GGA-8853496 SCF:FBXL7 binds AURKA IEA Gallus gallus A0A1D5P2L3 R-GGA-8854041 https://reactome.org/PathwayBrowser/#/R-GGA-8854041 SCF-FBXL7 ubiquitinates AURKA IEA Gallus gallus A0A1D5P2L3 R-GGA-8854044 https://reactome.org/PathwayBrowser/#/R-GGA-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Gallus gallus A0A1D5P2L3 R-GGA-8854051 https://reactome.org/PathwayBrowser/#/R-GGA-8854051 SCF-FBXL18 ubiquitinates FBXL7 IEA Gallus gallus A0A1D5P2L3 R-GGA-8854052 https://reactome.org/PathwayBrowser/#/R-GGA-8854052 Formation of the SCF-FBXL7 complex IEA Gallus gallus A0A1D5P2L3 R-GGA-8939688 https://reactome.org/PathwayBrowser/#/R-GGA-8939688 SCF(SKP2) complex binds RUNX2 IEA Gallus gallus A0A1D5P2L3 R-GGA-8939706 https://reactome.org/PathwayBrowser/#/R-GGA-8939706 SCF(SKP2) polyubiquitinates RUNX2 IEA Gallus gallus A0A1D5P2L3 R-GGA-8952618 https://reactome.org/PathwayBrowser/#/R-GGA-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P2L3 R-GGA-8952620 https://reactome.org/PathwayBrowser/#/R-GGA-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P2L3 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5P2L3 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5P2L3 R-GGA-8956200 https://reactome.org/PathwayBrowser/#/R-GGA-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P2L3 R-GGA-9708517 https://reactome.org/PathwayBrowser/#/R-GGA-9708517 FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2)) IEA Gallus gallus A0A1D5P2L3 R-GGA-9708525 https://reactome.org/PathwayBrowser/#/R-GGA-9708525 BACH1:FBXL17 binds SCF(SKP2) complex IEA Gallus gallus A0A1D5P2L3 R-GGA-9762091 https://reactome.org/PathwayBrowser/#/R-GGA-9762091 NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 IEA Gallus gallus A0A1D5P2L3 R-GGA-9762093 https://reactome.org/PathwayBrowser/#/R-GGA-9762093 BTRC binds p-S344, 347 NFE2L2 IEA Gallus gallus A0A1D5P2L3 R-GGA-9762096 https://reactome.org/PathwayBrowser/#/R-GGA-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Gallus gallus A0A1D5P2L3 R-GGA-976991 https://reactome.org/PathwayBrowser/#/R-GGA-976991 Prolactin receptor ligands bind the prolactin receptor IEA Gallus gallus A0A1D5P2L3 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5P2L3 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5P2L3 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5P2L3 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5P2N3 R-GGA-2160884 https://reactome.org/PathwayBrowser/#/R-GGA-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Gallus gallus A0A1D5P2N3 R-GGA-2160892 https://reactome.org/PathwayBrowser/#/R-GGA-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Gallus gallus A0A1D5P2N3 R-GGA-2160915 https://reactome.org/PathwayBrowser/#/R-GGA-2160915 Receptor-mediated uptake of HA IEA Gallus gallus A0A1D5P2N3 R-GGA-8853405 https://reactome.org/PathwayBrowser/#/R-GGA-8853405 TPX2 binds AURKA at centrosomes IEA Gallus gallus A0A1D5P2N3 R-GGA-8853419 https://reactome.org/PathwayBrowser/#/R-GGA-8853419 TPX2 promotes AURKA autophosphorylation IEA Gallus gallus A0A1D5P2Q0 R-GGA-2029476 https://reactome.org/PathwayBrowser/#/R-GGA-2029476 Role of myosins in phagosome formation IEA Gallus gallus A0A1D5P2Q0 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus A0A1D5P2Q0 R-GGA-8985594 https://reactome.org/PathwayBrowser/#/R-GGA-8985594 MYO9B inactivates RHOA IEA Gallus gallus A0A1D5P2Q0 R-GGA-9013009 https://reactome.org/PathwayBrowser/#/R-GGA-9013009 RHOA binds effectors at the plasma membrane IEA Gallus gallus A0A1D5P2Q0 R-GGA-9013022 https://reactome.org/PathwayBrowser/#/R-GGA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Gallus gallus A0A1D5P2Q0 R-GGA-9013024 https://reactome.org/PathwayBrowser/#/R-GGA-9013024 RHOB binds effectors at the plasma membrane IEA Gallus gallus A0A1D5P2Q0 R-GGA-9013110 https://reactome.org/PathwayBrowser/#/R-GGA-9013110 RHOC binds effectors at the plasma membrane IEA Gallus gallus A0A1D5P2Q0 R-GGA-9013111 https://reactome.org/PathwayBrowser/#/R-GGA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Gallus gallus A0A1D5P2Q0 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus A0A1D5P2Q0 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus A0A1D5P2Q0 R-GGA-9693282 https://reactome.org/PathwayBrowser/#/R-GGA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Gallus gallus A0A1D5P2Q1 R-GGA-1676114 https://reactome.org/PathwayBrowser/#/R-GGA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Gallus gallus A0A1D5P2Q1 R-GGA-1676124 https://reactome.org/PathwayBrowser/#/R-GGA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Gallus gallus A0A1D5P2Q1 R-GGA-1676133 https://reactome.org/PathwayBrowser/#/R-GGA-1676133 PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Gallus gallus A0A1D5P2Q6 R-GGA-428664 https://reactome.org/PathwayBrowser/#/R-GGA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Gallus gallus A0A1D5P2S0 R-GGA-2672334 https://reactome.org/PathwayBrowser/#/R-GGA-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Gallus gallus A0A1D5P2S0 R-GGA-2682349 https://reactome.org/PathwayBrowser/#/R-GGA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Gallus gallus A0A1D5P2U0 R-GGA-2032781 https://reactome.org/PathwayBrowser/#/R-GGA-2032781 WWTR1 (TAZ) binds TEAD IEA Gallus gallus A0A1D5P2U0 R-GGA-8871266 https://reactome.org/PathwayBrowser/#/R-GGA-8871266 YAP1 binds TEAD3 IEA Gallus gallus A0A1D5P2U0 R-GGA-8951676 https://reactome.org/PathwayBrowser/#/R-GGA-8951676 RUNX3 binds TEADs and YAP1 IEA Gallus gallus A0A1D5P2U8 R-GGA-140978 https://reactome.org/PathwayBrowser/#/R-GGA-140978 TRADD:TRAF2:RIP1 binds FADD IEA Gallus gallus A0A1D5P2U8 R-GGA-5357845 https://reactome.org/PathwayBrowser/#/R-GGA-5357845 K63polyUb-RIPK1 is deubiquitinated IEA Gallus gallus A0A1D5P2U8 R-GGA-5690827 https://reactome.org/PathwayBrowser/#/R-GGA-5690827 TNFAIP3 (A20) ubiquitinates RIPK1 IEA Gallus gallus A0A1D5P2U8 R-GGA-5690845 https://reactome.org/PathwayBrowser/#/R-GGA-5690845 TNIPs bind TNFAIP3 (A20) IEA Gallus gallus A0A1D5P2U8 R-GGA-5690856 https://reactome.org/PathwayBrowser/#/R-GGA-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Gallus gallus A0A1D5P2U8 R-GGA-5690870 https://reactome.org/PathwayBrowser/#/R-GGA-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Gallus gallus A0A1D5P2U8 R-GGA-5693055 https://reactome.org/PathwayBrowser/#/R-GGA-5693055 TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes IEA Gallus gallus A0A1D5P2U8 R-GGA-5693108 https://reactome.org/PathwayBrowser/#/R-GGA-5693108 TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains IEA Gallus gallus A0A1D5P2U8 R-GGA-8869506 https://reactome.org/PathwayBrowser/#/R-GGA-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Gallus gallus A0A1D5P2U8 R-GGA-937337 https://reactome.org/PathwayBrowser/#/R-GGA-937337 TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination IEA Gallus gallus A0A1D5P2V5 R-GGA-5692462 https://reactome.org/PathwayBrowser/#/R-GGA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Gallus gallus A0A1D5P2X6 R-GGA-2197770 https://reactome.org/PathwayBrowser/#/R-GGA-2197770 STAB1 (FEEL-1) binds ligands IEA Gallus gallus A0A1D5P2X6 R-GGA-2247513 https://reactome.org/PathwayBrowser/#/R-GGA-2247513 STAB1:ligand is endocytosed IEA Gallus gallus A0A1D5P2X9 R-GGA-399944 https://reactome.org/PathwayBrowser/#/R-GGA-399944 Phosphorylation of CRMPs by Cdk5 IEA Gallus gallus A0A1D5P2X9 R-GGA-399951 https://reactome.org/PathwayBrowser/#/R-GGA-399951 Phosphorylation of CRMPs by GSK3beta IEA Gallus gallus A0A1D5P2Z0 R-GGA-1675994 https://reactome.org/PathwayBrowser/#/R-GGA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Gallus gallus A0A1D5P2Z0 R-GGA-1676203 https://reactome.org/PathwayBrowser/#/R-GGA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Gallus gallus A0A1D5P2Z0 R-GGA-9693125 https://reactome.org/PathwayBrowser/#/R-GGA-9693125 RHOF binds effectors at the plasma membrane IEA Gallus gallus A0A1D5P308 R-GGA-913675 https://reactome.org/PathwayBrowser/#/R-GGA-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Gallus gallus A0A1D5P326 R-GGA-2470935 https://reactome.org/PathwayBrowser/#/R-GGA-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Gallus gallus A0A1D5P338 R-GGA-3323079 https://reactome.org/PathwayBrowser/#/R-GGA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus A0A1D5P338 R-GGA-71682 https://reactome.org/PathwayBrowser/#/R-GGA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus A0A1D5P346 R-GGA-5223313 https://reactome.org/PathwayBrowser/#/R-GGA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Gallus gallus A0A1D5P346 R-GGA-9759206 https://reactome.org/PathwayBrowser/#/R-GGA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Gallus gallus A0A1D5P360 R-GGA-1168459 https://reactome.org/PathwayBrowser/#/R-GGA-1168459 Lyn activates ERK IEA Gallus gallus A0A1D5P360 R-GGA-1433418 https://reactome.org/PathwayBrowser/#/R-GGA-1433418 Phosphorylation of JAK2 IEA Gallus gallus A0A1D5P360 R-GGA-1433428 https://reactome.org/PathwayBrowser/#/R-GGA-1433428 GRB2 is indirectly recruited to p-KIT through SHP2 IEA Gallus gallus A0A1D5P360 R-GGA-1433451 https://reactome.org/PathwayBrowser/#/R-GGA-1433451 JAK2 binds to p-KIT IEA Gallus gallus A0A1D5P360 R-GGA-1433454 https://reactome.org/PathwayBrowser/#/R-GGA-1433454 Phosphorylation of GAB2 by SFKs IEA Gallus gallus A0A1D5P360 R-GGA-1433456 https://reactome.org/PathwayBrowser/#/R-GGA-1433456 Recruitment of STATs IEA Gallus gallus A0A1D5P360 R-GGA-1433488 https://reactome.org/PathwayBrowser/#/R-GGA-1433488 Phosphorylation of SHP2 by SFKs IEA Gallus gallus A0A1D5P360 R-GGA-1433506 https://reactome.org/PathwayBrowser/#/R-GGA-1433506 Phosphorylation of APS IEA Gallus gallus A0A1D5P360 R-GGA-1433514 https://reactome.org/PathwayBrowser/#/R-GGA-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Gallus gallus A0A1D5P360 R-GGA-1470009 https://reactome.org/PathwayBrowser/#/R-GGA-1470009 Phosphorylation of STATs IEA Gallus gallus A0A1D5P360 R-GGA-1470010 https://reactome.org/PathwayBrowser/#/R-GGA-1470010 Dimerization of STATs IEA Gallus gallus A0A1D5P360 R-GGA-1470012 https://reactome.org/PathwayBrowser/#/R-GGA-1470012 Disassociation and translocation of STATs to the nucleus IEA Gallus gallus A0A1D5P360 R-GGA-1472121 https://reactome.org/PathwayBrowser/#/R-GGA-1472121 Phosphorylation of p-KIT on Y900 by Src kinases IEA Gallus gallus A0A1D5P360 R-GGA-1562641 https://reactome.org/PathwayBrowser/#/R-GGA-1562641 Indirect recruitment of PI3K to KIT via p(Y)-GAB2 IEA Gallus gallus A0A1D5P360 R-GGA-2029459 https://reactome.org/PathwayBrowser/#/R-GGA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Gallus gallus A0A1D5P360 R-GGA-205234 https://reactome.org/PathwayBrowser/#/R-GGA-205234 Indirect recruitment of GAB2 to p-KIT IEA Gallus gallus A0A1D5P360 R-GGA-205238 https://reactome.org/PathwayBrowser/#/R-GGA-205238 SHP2 interacts with p-KIT IEA Gallus gallus A0A1D5P360 R-GGA-205244 https://reactome.org/PathwayBrowser/#/R-GGA-205244 Recruitment of CBL to KIT IEA Gallus gallus A0A1D5P360 R-GGA-210291 https://reactome.org/PathwayBrowser/#/R-GGA-210291 Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src IEA Gallus gallus A0A1D5P360 R-GGA-2730862 https://reactome.org/PathwayBrowser/#/R-GGA-2730862 Autophosphorylation of LYN kinase IEA Gallus gallus A0A1D5P360 R-GGA-388829 https://reactome.org/PathwayBrowser/#/R-GGA-388829 SHP2 phosphatase binds CTLA-4 IEA Gallus gallus A0A1D5P360 R-GGA-388831 https://reactome.org/PathwayBrowser/#/R-GGA-388831 Phosphorylation of CD28 IEA Gallus gallus A0A1D5P360 R-GGA-3928604 https://reactome.org/PathwayBrowser/#/R-GGA-3928604 SFKs phosphorylate VAV2,3 IEA Gallus gallus A0A1D5P360 R-GGA-3928607 https://reactome.org/PathwayBrowser/#/R-GGA-3928607 p-EPHs bind VAV2,3 IEA Gallus gallus A0A1D5P360 R-GGA-3928627 https://reactome.org/PathwayBrowser/#/R-GGA-3928627 EPHB phosphorylates TIAM1 IEA Gallus gallus A0A1D5P360 R-GGA-3928628 https://reactome.org/PathwayBrowser/#/R-GGA-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5P360 R-GGA-3928642 https://reactome.org/PathwayBrowser/#/R-GGA-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5P360 R-GGA-3928645 https://reactome.org/PathwayBrowser/#/R-GGA-3928645 EPHB:NMDAR binds TIAM1 IEA Gallus gallus A0A1D5P360 R-GGA-3928651 https://reactome.org/PathwayBrowser/#/R-GGA-3928651 NGEF exchanges GTP for GDP on RHOA IEA Gallus gallus A0A1D5P360 R-GGA-4093327 https://reactome.org/PathwayBrowser/#/R-GGA-4093327 EPHA binds TIAM1 IEA Gallus gallus A0A1D5P360 R-GGA-4093336 https://reactome.org/PathwayBrowser/#/R-GGA-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5P360 R-GGA-5624486 https://reactome.org/PathwayBrowser/#/R-GGA-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Gallus gallus A0A1D5P360 R-GGA-879917 https://reactome.org/PathwayBrowser/#/R-GGA-879917 CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated IEA Gallus gallus A0A1D5P360 R-GGA-8942607 https://reactome.org/PathwayBrowser/#/R-GGA-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Gallus gallus A0A1D5P360 R-GGA-912627 https://reactome.org/PathwayBrowser/#/R-GGA-912627 CBL ubiquitinates PI3K IEA Gallus gallus A0A1D5P360 R-GGA-9674816 https://reactome.org/PathwayBrowser/#/R-GGA-9674816 p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS IEA Gallus gallus A0A1D5P360 R-GGA-9677579 https://reactome.org/PathwayBrowser/#/R-GGA-9677579 CSF3 dimer (GCSF dimer) binds CSF3R:JAK1:LYN IEA Gallus gallus A0A1D5P360 R-GGA-9677585 https://reactome.org/PathwayBrowser/#/R-GGA-9677585 CSF3 dimer:CSFR:LYN:JAK1 binds CSFR:LYN:JAK1 IEA Gallus gallus A0A1D5P360 R-GGA-9707977 https://reactome.org/PathwayBrowser/#/R-GGA-9707977 CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane IEA Gallus gallus A0A1D5P365 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5P375 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5P375 R-GGA-417843 https://reactome.org/PathwayBrowser/#/R-GGA-417843 P2Y13 binds ADP IEA Gallus gallus A0A1D5P375 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5P375 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5P384 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus A0A1D5P384 R-GGA-6799178 https://reactome.org/PathwayBrowser/#/R-GGA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Gallus gallus A0A1D5P384 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus A0A1D5P384 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus A0A1D5P384 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus A0A1D5P384 R-GGA-6799202 https://reactome.org/PathwayBrowser/#/R-GGA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Gallus gallus A0A1D5P392 R-GGA-8854588 https://reactome.org/PathwayBrowser/#/R-GGA-8854588 TBC1D25 (OATL1) binds ATG8 homologues IEA Gallus gallus A0A1D5P392 R-GGA-8854612 https://reactome.org/PathwayBrowser/#/R-GGA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Gallus gallus A0A1D5P395 R-GGA-1504186 https://reactome.org/PathwayBrowser/#/R-GGA-1504186 DVL recruits GSK3beta:AXIN1 to the receptor complex IEA Gallus gallus A0A1D5P395 R-GGA-195275 https://reactome.org/PathwayBrowser/#/R-GGA-195275 Phosphorylation of APC component of the destruction complex IEA Gallus gallus A0A1D5P395 R-GGA-195280 https://reactome.org/PathwayBrowser/#/R-GGA-195280 Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex IEA Gallus gallus A0A1D5P395 R-GGA-195283 https://reactome.org/PathwayBrowser/#/R-GGA-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Gallus gallus A0A1D5P395 R-GGA-195287 https://reactome.org/PathwayBrowser/#/R-GGA-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Gallus gallus A0A1D5P395 R-GGA-195300 https://reactome.org/PathwayBrowser/#/R-GGA-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Gallus gallus A0A1D5P395 R-GGA-195304 https://reactome.org/PathwayBrowser/#/R-GGA-195304 Association of beta-catenin with the destruction complex IEA Gallus gallus A0A1D5P395 R-GGA-195318 https://reactome.org/PathwayBrowser/#/R-GGA-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Gallus gallus A0A1D5P395 R-GGA-201677 https://reactome.org/PathwayBrowser/#/R-GGA-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Gallus gallus A0A1D5P395 R-GGA-2130279 https://reactome.org/PathwayBrowser/#/R-GGA-2130279 Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex IEA Gallus gallus A0A1D5P395 R-GGA-2130282 https://reactome.org/PathwayBrowser/#/R-GGA-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Gallus gallus A0A1D5P395 R-GGA-2130286 https://reactome.org/PathwayBrowser/#/R-GGA-2130286 Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) IEA Gallus gallus A0A1D5P395 R-GGA-3640844 https://reactome.org/PathwayBrowser/#/R-GGA-3640844 RNF146 binds RibC-AXIN:TNKS complex IEA Gallus gallus A0A1D5P395 R-GGA-3640858 https://reactome.org/PathwayBrowser/#/R-GGA-3640858 Tankyrase ADP-ribosylates AXIN IEA Gallus gallus A0A1D5P395 R-GGA-3640861 https://reactome.org/PathwayBrowser/#/R-GGA-3640861 RNF146 ubiquitinates ADP-ribosylated AXIN IEA Gallus gallus A0A1D5P395 R-GGA-3640862 https://reactome.org/PathwayBrowser/#/R-GGA-3640862 Tankyrase binds AXIN IEA Gallus gallus A0A1D5P395 R-GGA-3640872 https://reactome.org/PathwayBrowser/#/R-GGA-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Gallus gallus A0A1D5P395 R-GGA-3640874 https://reactome.org/PathwayBrowser/#/R-GGA-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5P395 R-GGA-4641129 https://reactome.org/PathwayBrowser/#/R-GGA-4641129 AXIN is ubiquitinated by SMURF2 IEA Gallus gallus A0A1D5P395 R-GGA-4641134 https://reactome.org/PathwayBrowser/#/R-GGA-4641134 SMURF2 binds AXIN IEA Gallus gallus A0A1D5P395 R-GGA-4641256 https://reactome.org/PathwayBrowser/#/R-GGA-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5P395 R-GGA-5229343 https://reactome.org/PathwayBrowser/#/R-GGA-5229343 AXIN is phosphorylated in the destruction complex IEA Gallus gallus A0A1D5P395 R-GGA-5368596 https://reactome.org/PathwayBrowser/#/R-GGA-5368596 WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 IEA Gallus gallus A0A1D5P3B1 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1D5P3B1 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1D5P3B1 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1D5P3B1 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1D5P3B1 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1D5P3B1 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5P3B1 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5P3C1 R-GGA-2025723 https://reactome.org/PathwayBrowser/#/R-GGA-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Gallus gallus A0A1D5P3C1 R-GGA-2046265 https://reactome.org/PathwayBrowser/#/R-GGA-2046265 B4GALTs transfer Gal to the keratan chain IEA Gallus gallus A0A1D5P3C1 R-GGA-2046298 https://reactome.org/PathwayBrowser/#/R-GGA-2046298 B4GALTs transfer Gal to a branch of keratan IEA Gallus gallus A0A1D5P3C1 R-GGA-975919 https://reactome.org/PathwayBrowser/#/R-GGA-975919 Addition of galactose by beta 4-galactosyltransferases IEA Gallus gallus A0A1D5P3C4 R-GGA-9018778 https://reactome.org/PathwayBrowser/#/R-GGA-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Gallus gallus A0A1D5P3C4 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5P3C4 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5P3C4 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5P3C4 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5P3F0 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1D5P3F3 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1D5P3F3 R-GGA-388529 https://reactome.org/PathwayBrowser/#/R-GGA-388529 Cholecystokinin receptors bind cholecystokinin IEA Gallus gallus A0A1D5P3F3 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1D5P3F3 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1D5P3F4 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1D5P3F4 R-GGA-444498 https://reactome.org/PathwayBrowser/#/R-GGA-444498 Thyrotropin-releasing hormone receptor binds thyrotropin IEA Gallus gallus A0A1D5P3F4 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1D5P3F4 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1D5P3F5 R-GGA-6798747 https://reactome.org/PathwayBrowser/#/R-GGA-6798747 Exocytosis of tertiary granule membrane proteins IEA Gallus gallus A0A1D5P3F5 R-GGA-6799350 https://reactome.org/PathwayBrowser/#/R-GGA-6799350 Exocytosis of specific granule membrane proteins IEA Gallus gallus A0A1D5P3G6 R-GGA-109539 https://reactome.org/PathwayBrowser/#/R-GGA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Gallus gallus A0A1D5P3G6 R-GGA-9751037 https://reactome.org/PathwayBrowser/#/R-GGA-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Gallus gallus A0A1D5P3G6 R-GGA-9754934 https://reactome.org/PathwayBrowser/#/R-GGA-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Gallus gallus A0A1D5P3H4 R-GGA-201443 https://reactome.org/PathwayBrowser/#/R-GGA-201443 Type II receptor phosphorylates type I receptor IEA Gallus gallus A0A1D5P3H4 R-GGA-201453 https://reactome.org/PathwayBrowser/#/R-GGA-201453 Phospho-R-Smad1/5/8 dissociates from the receptor complex IEA Gallus gallus A0A1D5P3H4 R-GGA-201457 https://reactome.org/PathwayBrowser/#/R-GGA-201457 BMP2 binds to the receptor complex IEA Gallus gallus A0A1D5P3H4 R-GGA-201475 https://reactome.org/PathwayBrowser/#/R-GGA-201475 I-Smad competes with R-Smad1/5/8 for type I receptor IEA Gallus gallus A0A1D5P3H4 R-GGA-201476 https://reactome.org/PathwayBrowser/#/R-GGA-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Gallus gallus A0A1D5P3H4 R-GGA-201648 https://reactome.org/PathwayBrowser/#/R-GGA-201648 An anchoring protein, Endofin, recruits R-Smad1/5/8 IEA Gallus gallus A0A1D5P3H4 R-GGA-201810 https://reactome.org/PathwayBrowser/#/R-GGA-201810 The ligand trap binds the ligand BMP2, blocking BMP signalling IEA Gallus gallus A0A1D5P3H4 R-GGA-201821 https://reactome.org/PathwayBrowser/#/R-GGA-201821 I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated IEA Gallus gallus A0A1D5P3H4 R-GGA-2396399 https://reactome.org/PathwayBrowser/#/R-GGA-2396399 Fibrillins bind BMPs IEA Gallus gallus A0A1D5P3I5 R-GGA-1675883 https://reactome.org/PathwayBrowser/#/R-GGA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Gallus gallus A0A1D5P3I5 R-GGA-1676152 https://reactome.org/PathwayBrowser/#/R-GGA-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Gallus gallus A0A1D5P3J8 R-GGA-200651 https://reactome.org/PathwayBrowser/#/R-GGA-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Gallus gallus A0A1D5P3J8 R-GGA-200735 https://reactome.org/PathwayBrowser/#/R-GGA-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Gallus gallus A0A1D5P3J8 R-GGA-71249 https://reactome.org/PathwayBrowser/#/R-GGA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Gallus gallus A0A1D5P3K1 R-GGA-2997723 https://reactome.org/PathwayBrowser/#/R-GGA-2997723 PIAS4 SUMOylates TP53BP1 with SUMO1 IEA Gallus gallus A0A1D5P3K1 R-GGA-5683384 https://reactome.org/PathwayBrowser/#/R-GGA-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Gallus gallus A0A1D5P3K1 R-GGA-5683385 https://reactome.org/PathwayBrowser/#/R-GGA-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Gallus gallus A0A1D5P3K1 R-GGA-5683425 https://reactome.org/PathwayBrowser/#/R-GGA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Gallus gallus A0A1D5P3K1 R-GGA-5683735 https://reactome.org/PathwayBrowser/#/R-GGA-5683735 CHEK2 is recruited to DNA DSBs IEA Gallus gallus A0A1D5P3K1 R-GGA-5683801 https://reactome.org/PathwayBrowser/#/R-GGA-5683801 CHEK2 phosphorylates BRCA1 IEA Gallus gallus A0A1D5P3K1 R-GGA-5684052 https://reactome.org/PathwayBrowser/#/R-GGA-5684052 PIAS4 SUMOylates MDC1 IEA Gallus gallus A0A1D5P3K1 R-GGA-5686685 https://reactome.org/PathwayBrowser/#/R-GGA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Gallus gallus A0A1D5P3K1 R-GGA-5686704 https://reactome.org/PathwayBrowser/#/R-GGA-5686704 Activated ATM phosphorylates DCLRE1C IEA Gallus gallus A0A1D5P3K1 R-GGA-5686900 https://reactome.org/PathwayBrowser/#/R-GGA-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Gallus gallus A0A1D5P3K1 R-GGA-5693551 https://reactome.org/PathwayBrowser/#/R-GGA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Gallus gallus A0A1D5P3K1 R-GGA-5693566 https://reactome.org/PathwayBrowser/#/R-GGA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Gallus gallus A0A1D5P3K1 R-GGA-69891 https://reactome.org/PathwayBrowser/#/R-GGA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Gallus gallus A0A1D5P3K4 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus A0A1D5P3K4 R-GGA-6799178 https://reactome.org/PathwayBrowser/#/R-GGA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Gallus gallus A0A1D5P3K4 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus A0A1D5P3K4 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus A0A1D5P3K4 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus A0A1D5P3K4 R-GGA-6799202 https://reactome.org/PathwayBrowser/#/R-GGA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Gallus gallus A0A1D5P3K5 R-GGA-8863463 https://reactome.org/PathwayBrowser/#/R-GGA-8863463 STON2 binds SYT proteins IEA Gallus gallus A0A1D5P3K5 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5P3K5 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5P3K5 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5P3K5 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5P3K5 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5P3K5 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5P3K5 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5P3K5 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5P3K5 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P3K5 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P3K5 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5P3K5 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5P3K6 R-GGA-909718 https://reactome.org/PathwayBrowser/#/R-GGA-909718 Formation of p-STAT1 homodimer IEA Gallus gallus A0A1D5P3K6 R-GGA-909719 https://reactome.org/PathwayBrowser/#/R-GGA-909719 Recruitment of STAT2 to p-IFNAR1 IEA Gallus gallus A0A1D5P3K6 R-GGA-909720 https://reactome.org/PathwayBrowser/#/R-GGA-909720 IFN alpha/beta binds to IFNAR2 IEA Gallus gallus A0A1D5P3K6 R-GGA-909722 https://reactome.org/PathwayBrowser/#/R-GGA-909722 Release of p-STAT2:p-STAT1 dimer IEA Gallus gallus A0A1D5P3K6 R-GGA-909724 https://reactome.org/PathwayBrowser/#/R-GGA-909724 Recruitment of IFNAR1 IEA Gallus gallus A0A1D5P3K6 R-GGA-909729 https://reactome.org/PathwayBrowser/#/R-GGA-909729 Activation of JAK kinases IEA Gallus gallus A0A1D5P3K6 R-GGA-909730 https://reactome.org/PathwayBrowser/#/R-GGA-909730 Phosphorylation of INFAR1 by TYK2 IEA Gallus gallus A0A1D5P3K6 R-GGA-909732 https://reactome.org/PathwayBrowser/#/R-GGA-909732 Phosphorylation of STAT2 IEA Gallus gallus A0A1D5P3K6 R-GGA-912685 https://reactome.org/PathwayBrowser/#/R-GGA-912685 UBP43 binds IFNAR2 and prevents JAK1 interaction IEA Gallus gallus A0A1D5P3K6 R-GGA-9678935 https://reactome.org/PathwayBrowser/#/R-GGA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Gallus gallus A0A1D5P3K6 R-GGA-9696179 https://reactome.org/PathwayBrowser/#/R-GGA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Gallus gallus A0A1D5P3K6 R-GGA-997309 https://reactome.org/PathwayBrowser/#/R-GGA-997309 Dephosphorylation of STAT1 by SHP2 IEA Gallus gallus A0A1D5P3K6 R-GGA-997311 https://reactome.org/PathwayBrowser/#/R-GGA-997311 Dephosphorylation of TYK2 by PTP1B IEA Gallus gallus A0A1D5P3K6 R-GGA-997314 https://reactome.org/PathwayBrowser/#/R-GGA-997314 Dephosphorylation of JAK1 by SHP1 IEA Gallus gallus A0A1D5P3M3 R-GGA-1299297 https://reactome.org/PathwayBrowser/#/R-GGA-1299297 Activation of THIK IEA Gallus gallus A0A1D5P3M3 R-GGA-5578910 https://reactome.org/PathwayBrowser/#/R-GGA-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Gallus gallus A0A1D5P3M9 R-GGA-5685011 https://reactome.org/PathwayBrowser/#/R-GGA-5685011 ATR activation at DNA DSBs IEA Gallus gallus A0A1D5P3M9 R-GGA-5685156 https://reactome.org/PathwayBrowser/#/R-GGA-5685156 ATR phosphorylates RPA2 IEA Gallus gallus A0A1D5P3M9 R-GGA-5686642 https://reactome.org/PathwayBrowser/#/R-GGA-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Gallus gallus A0A1D5P3M9 R-GGA-5693564 https://reactome.org/PathwayBrowser/#/R-GGA-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Gallus gallus A0A1D5P3M9 R-GGA-5693580 https://reactome.org/PathwayBrowser/#/R-GGA-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Gallus gallus A0A1D5P3P8 R-GGA-3788075 https://reactome.org/PathwayBrowser/#/R-GGA-3788075 Brevican degradation by ADAMTS4, ADAMTS5 IEA Gallus gallus A0A1D5P3P8 R-GGA-5173005 https://reactome.org/PathwayBrowser/#/R-GGA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Gallus gallus A0A1D5P3P8 R-GGA-5173192 https://reactome.org/PathwayBrowser/#/R-GGA-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Gallus gallus A0A1D5P3Q1 R-GGA-2018682 https://reactome.org/PathwayBrowser/#/R-GGA-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Gallus gallus A0A1D5P3S3 R-GGA-3640844 https://reactome.org/PathwayBrowser/#/R-GGA-3640844 RNF146 binds RibC-AXIN:TNKS complex IEA Gallus gallus A0A1D5P3S3 R-GGA-3640858 https://reactome.org/PathwayBrowser/#/R-GGA-3640858 Tankyrase ADP-ribosylates AXIN IEA Gallus gallus A0A1D5P3S3 R-GGA-3640861 https://reactome.org/PathwayBrowser/#/R-GGA-3640861 RNF146 ubiquitinates ADP-ribosylated AXIN IEA Gallus gallus A0A1D5P3S3 R-GGA-3640862 https://reactome.org/PathwayBrowser/#/R-GGA-3640862 Tankyrase binds AXIN IEA Gallus gallus A0A1D5P3S3 R-GGA-3640872 https://reactome.org/PathwayBrowser/#/R-GGA-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Gallus gallus A0A1D5P3S3 R-GGA-3640874 https://reactome.org/PathwayBrowser/#/R-GGA-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5P3S3 R-GGA-8948800 https://reactome.org/PathwayBrowser/#/R-GGA-8948800 TNKS and TNKS2 PARylate PTEN IEA Gallus gallus A0A1D5P3S8 R-GGA-197958 https://reactome.org/PathwayBrowser/#/R-GGA-197958 FPGS-2 transforms THF to THFPG IEA Gallus gallus A0A1D5P3S8 R-GGA-200681 https://reactome.org/PathwayBrowser/#/R-GGA-200681 FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG IEA Gallus gallus A0A1D5P3S8 R-GGA-200682 https://reactome.org/PathwayBrowser/#/R-GGA-200682 Mitochondrial FPGS-1 transforms THF to THFPG IEA Gallus gallus A0A1D5P3S9 R-GGA-109338 https://reactome.org/PathwayBrowser/#/R-GGA-109338 Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA IEA Gallus gallus A0A1D5P3S9 R-GGA-109998 https://reactome.org/PathwayBrowser/#/R-GGA-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Gallus gallus A0A1D5P3S9 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1D5P3S9 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1D5P3U0 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus A0A1D5P3U2 R-GGA-211951 https://reactome.org/PathwayBrowser/#/R-GGA-211951 CYP1B1 4-hydroxylates EST17b IEA Gallus gallus A0A1D5P3U2 R-GGA-5692283 https://reactome.org/PathwayBrowser/#/R-GGA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Gallus gallus A0A1D5P3U2 R-GGA-76472 https://reactome.org/PathwayBrowser/#/R-GGA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Gallus gallus A0A1D5P3U2 R-GGA-8936849 https://reactome.org/PathwayBrowser/#/R-GGA-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Gallus gallus A0A1D5P3U2 R-GGA-8937169 https://reactome.org/PathwayBrowser/#/R-GGA-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Gallus gallus A0A1D5P3U2 R-GGA-8937177 https://reactome.org/PathwayBrowser/#/R-GGA-8937177 AHR:TCDD binds ARNT IEA Gallus gallus A0A1D5P3U2 R-GGA-8937191 https://reactome.org/PathwayBrowser/#/R-GGA-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates IEA Gallus gallus A0A1D5P3U7 R-GGA-210420 https://reactome.org/PathwayBrowser/#/R-GGA-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Gallus gallus A0A1D5P3U7 R-GGA-265645 https://reactome.org/PathwayBrowser/#/R-GGA-265645 Calcium Influx through Voltage-gated Calcium Channels IEA Gallus gallus A0A1D5P3U9 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus A0A1D5P3X7 R-GGA-112381 https://reactome.org/PathwayBrowser/#/R-GGA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Gallus gallus A0A1D5P3X7 R-GGA-112385 https://reactome.org/PathwayBrowser/#/R-GGA-112385 Addition of nucleotides leads to transcript elongation IEA Gallus gallus A0A1D5P3X7 R-GGA-112392 https://reactome.org/PathwayBrowser/#/R-GGA-112392 Resumption of elongation after recovery from pausing IEA Gallus gallus A0A1D5P3X7 R-GGA-112395 https://reactome.org/PathwayBrowser/#/R-GGA-112395 Abortive termination of elongation after arrest IEA Gallus gallus A0A1D5P3X7 R-GGA-112396 https://reactome.org/PathwayBrowser/#/R-GGA-112396 Separation of elongating transcript from template IEA Gallus gallus A0A1D5P3X7 R-GGA-113411 https://reactome.org/PathwayBrowser/#/R-GGA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Gallus gallus A0A1D5P3X7 R-GGA-113412 https://reactome.org/PathwayBrowser/#/R-GGA-113412 Pol II elongation complex moves on the template as transcript elongates IEA Gallus gallus A0A1D5P3X7 R-GGA-113413 https://reactome.org/PathwayBrowser/#/R-GGA-113413 TFIIS-mediated recovery of elongation from arrest IEA Gallus gallus A0A1D5P3X7 R-GGA-113414 https://reactome.org/PathwayBrowser/#/R-GGA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Gallus gallus A0A1D5P3Y4 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5P3Y4 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5P3Y4 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5P3Y4 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5P3Y4 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5P3Y8 R-GGA-5333678 https://reactome.org/PathwayBrowser/#/R-GGA-5333678 CPNEs bind PL IEA Gallus gallus A0A1D5P3Y8 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5P3Z1 R-GGA-9934893 https://reactome.org/PathwayBrowser/#/R-GGA-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 IEA Gallus gallus A0A1D5P3Z3 R-GGA-6786650 https://reactome.org/PathwayBrowser/#/R-GGA-6786650 DDHD1,2 hydrolyse PA IEA Gallus gallus A0A1D5P401 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5P401 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5P401 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus A0A1D5P405 R-GGA-110011 https://reactome.org/PathwayBrowser/#/R-GGA-110011 Binding of Grb10 to the insulin receptor IEA Gallus gallus A0A1D5P405 R-GGA-1433501 https://reactome.org/PathwayBrowser/#/R-GGA-1433501 Interaction of other adapter proteins with p-KIT IEA Gallus gallus A0A1D5P405 R-GGA-74707 https://reactome.org/PathwayBrowser/#/R-GGA-74707 Binding of IRS to insulin receptor IEA Gallus gallus A0A1D5P405 R-GGA-74740 https://reactome.org/PathwayBrowser/#/R-GGA-74740 Binding of SHC1 to insulin receptor IEA Gallus gallus A0A1D5P405 R-GGA-8853753 https://reactome.org/PathwayBrowser/#/R-GGA-8853753 2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 IEA Gallus gallus A0A1D5P405 R-GGA-9706345 https://reactome.org/PathwayBrowser/#/R-GGA-9706345 Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA IEA Gallus gallus A0A1D5P406 R-GGA-6785342 https://reactome.org/PathwayBrowser/#/R-GGA-6785342 FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex IEA Gallus gallus A0A1D5P406 R-GGA-6785361 https://reactome.org/PathwayBrowser/#/R-GGA-6785361 Monoubiquitination of FANCD2:FANCI IEA Gallus gallus A0A1D5P406 R-GGA-6786171 https://reactome.org/PathwayBrowser/#/R-GGA-6786171 FANCD2 deubiquitination by USP1:WDR48 IEA Gallus gallus A0A1D5P406 R-GGA-6788385 https://reactome.org/PathwayBrowser/#/R-GGA-6788385 The complex of ATR and ATRIP is recruited to ICL-DNA IEA Gallus gallus A0A1D5P406 R-GGA-6788392 https://reactome.org/PathwayBrowser/#/R-GGA-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Gallus gallus A0A1D5P406 R-GGA-9835411 https://reactome.org/PathwayBrowser/#/R-GGA-9835411 FA core complex:HSP70s binds PKR IEA Gallus gallus A0A1D5P420 R-GGA-5682388 https://reactome.org/PathwayBrowser/#/R-GGA-5682388 Autophagosome maturation IEA Gallus gallus A0A1D5P420 R-GGA-917693 https://reactome.org/PathwayBrowser/#/R-GGA-917693 ESCRT Disassembly IEA Gallus gallus A0A1D5P420 R-GGA-917700 https://reactome.org/PathwayBrowser/#/R-GGA-917700 MVB Vesicle Formation IEA Gallus gallus A0A1D5P420 R-GGA-9647619 https://reactome.org/PathwayBrowser/#/R-GGA-9647619 GSDMD forms ring‐shaped oligomers IEA Gallus gallus A0A1D5P420 R-GGA-9668389 https://reactome.org/PathwayBrowser/#/R-GGA-9668389 VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations IEA Gallus gallus A0A1D5P420 R-GGA-9668395 https://reactome.org/PathwayBrowser/#/R-GGA-9668395 CHMP7 binds CC2D1B IEA Gallus gallus A0A1D5P420 R-GGA-9668405 https://reactome.org/PathwayBrowser/#/R-GGA-9668405 SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin IEA Gallus gallus A0A1D5P421 R-GGA-9606884 https://reactome.org/PathwayBrowser/#/R-GGA-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Gallus gallus A0A1D5P421 R-GGA-9606894 https://reactome.org/PathwayBrowser/#/R-GGA-9606894 p-DAPP1 (p-BAM32) binds PLCG2 IEA Gallus gallus A0A1D5P434 R-GGA-2161282 https://reactome.org/PathwayBrowser/#/R-GGA-2161282 Elastic fibres bind associated proteins IEA Gallus gallus A0A1D5P445 R-GGA-3928578 https://reactome.org/PathwayBrowser/#/R-GGA-3928578 EPH receptors autophosphorylate IEA Gallus gallus A0A1D5P445 R-GGA-3928591 https://reactome.org/PathwayBrowser/#/R-GGA-3928591 EPH:EFN tetramers oligomerise IEA Gallus gallus A0A1D5P445 R-GGA-3928597 https://reactome.org/PathwayBrowser/#/R-GGA-3928597 EPH:EFN dimers tetramerise IEA Gallus gallus A0A1D5P445 R-GGA-3928604 https://reactome.org/PathwayBrowser/#/R-GGA-3928604 SFKs phosphorylate VAV2,3 IEA Gallus gallus A0A1D5P445 R-GGA-3928607 https://reactome.org/PathwayBrowser/#/R-GGA-3928607 p-EPHs bind VAV2,3 IEA Gallus gallus A0A1D5P445 R-GGA-3928628 https://reactome.org/PathwayBrowser/#/R-GGA-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5P445 R-GGA-3928642 https://reactome.org/PathwayBrowser/#/R-GGA-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5P445 R-GGA-3928646 https://reactome.org/PathwayBrowser/#/R-GGA-3928646 EPHAs bind EFNAs IEA Gallus gallus A0A1D5P445 R-GGA-3928651 https://reactome.org/PathwayBrowser/#/R-GGA-3928651 NGEF exchanges GTP for GDP on RHOA IEA Gallus gallus A0A1D5P445 R-GGA-4093327 https://reactome.org/PathwayBrowser/#/R-GGA-4093327 EPHA binds TIAM1 IEA Gallus gallus A0A1D5P462 R-GGA-156808 https://reactome.org/PathwayBrowser/#/R-GGA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Gallus gallus A0A1D5P462 R-GGA-157849 https://reactome.org/PathwayBrowser/#/R-GGA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Gallus gallus A0A1D5P462 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1D5P462 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus A0A1D5P462 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1D5P462 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1D5P462 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1D5P462 R-GGA-72676 https://reactome.org/PathwayBrowser/#/R-GGA-72676 eIF3 and eIF1A bind to the 40S subunit IEA Gallus gallus A0A1D5P462 R-GGA-72691 https://reactome.org/PathwayBrowser/#/R-GGA-72691 Formation of the 43S pre-initiation complex IEA Gallus gallus A0A1D5P462 R-GGA-72697 https://reactome.org/PathwayBrowser/#/R-GGA-72697 Start codon recognition IEA Gallus gallus A0A1D5P462 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1D5P462 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5P462 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5P462 R-GGA-9630769 https://reactome.org/PathwayBrowser/#/R-GGA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Gallus gallus A0A1D5P463 R-GGA-5675373 https://reactome.org/PathwayBrowser/#/R-GGA-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Gallus gallus A0A1D5P467 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus A0A1D5P467 R-GGA-3928595 https://reactome.org/PathwayBrowser/#/R-GGA-3928595 N-WASP binds ARP2/3 and G-actin IEA Gallus gallus A0A1D5P467 R-GGA-3928601 https://reactome.org/PathwayBrowser/#/R-GGA-3928601 CDC42 and PIP2 bind WASL, activating it IEA Gallus gallus A0A1D5P467 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus A0A1D5P467 R-GGA-8856813 https://reactome.org/PathwayBrowser/#/R-GGA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Gallus gallus A0A1D5P467 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5P467 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5P467 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5P467 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5P467 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5P467 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5P467 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5P467 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5P467 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P467 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P467 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5P467 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5P467 R-GGA-9013159 https://reactome.org/PathwayBrowser/#/R-GGA-9013159 CDC42 GEFs activate CDC42 IEA Gallus gallus A0A1D5P467 R-GGA-9014433 https://reactome.org/PathwayBrowser/#/R-GGA-9014433 RHOG GEFs activate RHOG IEA Gallus gallus A0A1D5P467 R-GGA-9018747 https://reactome.org/PathwayBrowser/#/R-GGA-9018747 RHOQ GEFs activate RHOQ IEA Gallus gallus A0A1D5P470 R-GGA-176054 https://reactome.org/PathwayBrowser/#/R-GGA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Gallus gallus A0A1D5P470 R-GGA-9026777 https://reactome.org/PathwayBrowser/#/R-GGA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Gallus gallus A0A1D5P470 R-GGA-9748996 https://reactome.org/PathwayBrowser/#/R-GGA-9748996 GST dimers cleave AZA to 6MP IEA Gallus gallus A0A1D5P470 R-GGA-9753280 https://reactome.org/PathwayBrowser/#/R-GGA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Gallus gallus A0A1D5P472 R-GGA-443997 https://reactome.org/PathwayBrowser/#/R-GGA-443997 SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol IEA Gallus gallus A0A1D5P476 R-GGA-8852130 https://reactome.org/PathwayBrowser/#/R-GGA-8852130 UBA1 conjugates ubiquitin to nuclear E2 enzymes IEA Gallus gallus A0A1D5P476 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5P476 R-GGA-983152 https://reactome.org/PathwayBrowser/#/R-GGA-983152 Transfer of ubiquitin from E1 to E2 IEA Gallus gallus A0A1D5P476 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5P476 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5P482 R-GGA-6814555 https://reactome.org/PathwayBrowser/#/R-GGA-6814555 Integrator complex processes the 3' end of snRNA IEA Gallus gallus A0A1D5P482 R-GGA-6814559 https://reactome.org/PathwayBrowser/#/R-GGA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Gallus gallus A0A1D5P490 R-GGA-156808 https://reactome.org/PathwayBrowser/#/R-GGA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Gallus gallus A0A1D5P490 R-GGA-157849 https://reactome.org/PathwayBrowser/#/R-GGA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Gallus gallus A0A1D5P490 R-GGA-165766 https://reactome.org/PathwayBrowser/#/R-GGA-165766 Phosphorylation and activation of eIF4G by activated S6K1 IEA Gallus gallus A0A1D5P490 R-GGA-1678842 https://reactome.org/PathwayBrowser/#/R-GGA-1678842 Competitive inhibition of translation initiation by ISGylated 4EHP IEA Gallus gallus A0A1D5P490 R-GGA-429955 https://reactome.org/PathwayBrowser/#/R-GGA-429955 CCR4-NOT complex deadenylates mRNA IEA Gallus gallus A0A1D5P490 R-GGA-429992 https://reactome.org/PathwayBrowser/#/R-GGA-429992 PARN deadenylates mRNA IEA Gallus gallus A0A1D5P490 R-GGA-430021 https://reactome.org/PathwayBrowser/#/R-GGA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Gallus gallus A0A1D5P490 R-GGA-450580 https://reactome.org/PathwayBrowser/#/R-GGA-450580 AUF1 (hnRNP D0) is ubiquitinylated IEA Gallus gallus A0A1D5P490 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus A0A1D5P490 R-GGA-72697 https://reactome.org/PathwayBrowser/#/R-GGA-72697 Start codon recognition IEA Gallus gallus A0A1D5P490 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1D5P490 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5P490 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5P494 R-GGA-975926 https://reactome.org/PathwayBrowser/#/R-GGA-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Gallus gallus A0A1D5P4A2 R-GGA-1237325 https://reactome.org/PathwayBrowser/#/R-GGA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Gallus gallus A0A1D5P4A2 R-GGA-1247668 https://reactome.org/PathwayBrowser/#/R-GGA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Gallus gallus A0A1D5P4A2 R-GGA-2168885 https://reactome.org/PathwayBrowser/#/R-GGA-2168885 Haptoglobin binds Hemoglobin IEA Gallus gallus A0A1D5P4A2 R-GGA-2230938 https://reactome.org/PathwayBrowser/#/R-GGA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Gallus gallus A0A1D5P4A2 R-GGA-6798745 https://reactome.org/PathwayBrowser/#/R-GGA-6798745 Exocytosis of tertiary granule lumen proteins IEA Gallus gallus A0A1D5P4A2 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5P4A2 R-GGA-6806831 https://reactome.org/PathwayBrowser/#/R-GGA-6806831 CYB5Rs reduce MetHb to HbA IEA Gallus gallus A0A1D5P4A2 R-GGA-9707504 https://reactome.org/PathwayBrowser/#/R-GGA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Gallus gallus A0A1D5P4A2 R-GGA-9707516 https://reactome.org/PathwayBrowser/#/R-GGA-9707516 FeHM dissociates from MetHb IEA Gallus gallus A0A1D5P4A2 R-GGA-9709317 https://reactome.org/PathwayBrowser/#/R-GGA-9709317 CO binds to free ferrohemoglobin IEA Gallus gallus A0A1D5P4A2 R-GGA-9709360 https://reactome.org/PathwayBrowser/#/R-GGA-9709360 H2O2 reduces MetHb IEA Gallus gallus A0A1D5P4A3 R-GGA-3295579 https://reactome.org/PathwayBrowser/#/R-GGA-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Gallus gallus A0A1D5P4A3 R-GGA-917936 https://reactome.org/PathwayBrowser/#/R-GGA-917936 MCOLN1 transports Fe2+ from endosome lumen to cytosol IEA Gallus gallus A0A1D5P4B1 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus A0A1D5P4B1 R-GGA-6799178 https://reactome.org/PathwayBrowser/#/R-GGA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Gallus gallus A0A1D5P4B1 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus A0A1D5P4B1 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus A0A1D5P4B1 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus A0A1D5P4B1 R-GGA-6799202 https://reactome.org/PathwayBrowser/#/R-GGA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Gallus gallus A0A1D5P4B8 R-GGA-6805640 https://reactome.org/PathwayBrowser/#/R-GGA-6805640 AKT phosphorylates KAT6A IEA Gallus gallus A0A1D5P4C1 R-GGA-209891 https://reactome.org/PathwayBrowser/#/R-GGA-209891 Dopamine is oxidised to noradrenaline IEA Gallus gallus A0A1D5P4C7 R-GGA-399944 https://reactome.org/PathwayBrowser/#/R-GGA-399944 Phosphorylation of CRMPs by Cdk5 IEA Gallus gallus A0A1D5P4C7 R-GGA-399947 https://reactome.org/PathwayBrowser/#/R-GGA-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Gallus gallus A0A1D5P4C7 R-GGA-399951 https://reactome.org/PathwayBrowser/#/R-GGA-399951 Phosphorylation of CRMPs by GSK3beta IEA Gallus gallus A0A1D5P4D9 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5P4D9 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5P4D9 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5P4D9 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5P4F0 R-GGA-374214 https://reactome.org/PathwayBrowser/#/R-GGA-374214 Receptors CXCR4 and 7 bind CXCL12 ligand IEA Gallus gallus A0A1D5P4F0 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5P4F0 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5P4F0 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5P4G6 R-GGA-1236956 https://reactome.org/PathwayBrowser/#/R-GGA-1236956 Engulfment of particulate antigen into phagocytic vesicle IEA Gallus gallus A0A1D5P4G6 R-GGA-1236958 https://reactome.org/PathwayBrowser/#/R-GGA-1236958 Interaction of particulate antigens with dendritic cell receptors IEA Gallus gallus A0A1D5P4G6 R-GGA-210304 https://reactome.org/PathwayBrowser/#/R-GGA-210304 Interaction of integrin alphaVbeta3 with PECAM1 IEA Gallus gallus A0A1D5P4G6 R-GGA-216050 https://reactome.org/PathwayBrowser/#/R-GGA-216050 Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix IEA Gallus gallus A0A1D5P4G6 R-GGA-216076 https://reactome.org/PathwayBrowser/#/R-GGA-216076 VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 IEA Gallus gallus A0A1D5P4G6 R-GGA-2328037 https://reactome.org/PathwayBrowser/#/R-GGA-2328037 Fibrillin-1 binds integrins IEA Gallus gallus A0A1D5P4G6 R-GGA-2395320 https://reactome.org/PathwayBrowser/#/R-GGA-2395320 Latent TGF-beta-1 binds integrins IEA Gallus gallus A0A1D5P4G6 R-GGA-2396029 https://reactome.org/PathwayBrowser/#/R-GGA-2396029 Latent TGF-beta-3 binds integrins IEA Gallus gallus A0A1D5P4G6 R-GGA-2426259 https://reactome.org/PathwayBrowser/#/R-GGA-2426259 COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 IEA Gallus gallus A0A1D5P4G6 R-GGA-2426471 https://reactome.org/PathwayBrowser/#/R-GGA-2426471 VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 IEA Gallus gallus A0A1D5P4G6 R-GGA-265423 https://reactome.org/PathwayBrowser/#/R-GGA-265423 Interaction of integrin alphaVbeta3 with Fibrillin IEA Gallus gallus A0A1D5P4G6 R-GGA-265425 https://reactome.org/PathwayBrowser/#/R-GGA-265425 Interaction of integrin alphaVbeta3 with von Willbrand Factor IEA Gallus gallus A0A1D5P4G6 R-GGA-265426 https://reactome.org/PathwayBrowser/#/R-GGA-265426 Interaction of integrin alphaVbeta3 with Tenascin IEA Gallus gallus A0A1D5P4G6 R-GGA-265427 https://reactome.org/PathwayBrowser/#/R-GGA-265427 Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) IEA Gallus gallus A0A1D5P4G6 R-GGA-2681667 https://reactome.org/PathwayBrowser/#/R-GGA-2681667 TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 IEA Gallus gallus A0A1D5P4G6 R-GGA-2731074 https://reactome.org/PathwayBrowser/#/R-GGA-2731074 Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) IEA Gallus gallus A0A1D5P4G6 R-GGA-4085087 https://reactome.org/PathwayBrowser/#/R-GGA-4085087 Canstatin binds integrins alphaVbeta3, alphaVbeta5 IEA Gallus gallus A0A1D5P4G6 R-GGA-4088218 https://reactome.org/PathwayBrowser/#/R-GGA-4088218 Tetrastatin binds integrin alphaVbeta3 IEA Gallus gallus A0A1D5P4G6 R-GGA-5218818 https://reactome.org/PathwayBrowser/#/R-GGA-5218818 Integrin alphaVbeta3 binds p-6Y-VEGFR2 IEA Gallus gallus A0A1D5P4G6 R-GGA-5218830 https://reactome.org/PathwayBrowser/#/R-GGA-5218830 SRC-1 phosphorylates PTK2-beta IEA Gallus gallus A0A1D5P4G6 R-GGA-5218836 https://reactome.org/PathwayBrowser/#/R-GGA-5218836 PTK2beta binds alphaVbeta3 IEA Gallus gallus A0A1D5P4G6 R-GGA-5218851 https://reactome.org/PathwayBrowser/#/R-GGA-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 IEA Gallus gallus A0A1D5P4G6 R-GGA-6799350 https://reactome.org/PathwayBrowser/#/R-GGA-6799350 Exocytosis of specific granule membrane proteins IEA Gallus gallus A0A1D5P4G6 R-GGA-9861484 https://reactome.org/PathwayBrowser/#/R-GGA-9861484 Phosphorylation of PTK2 (FAK) on tyrosine-397 in response to turbulent blood flow IEA Gallus gallus A0A1D5P4I6 R-GGA-9933236 https://reactome.org/PathwayBrowser/#/R-GGA-9933236 SS18-containing ATPase complex binds SMARCC dimer:SMARCDs:BICRAs:BRD9 IEA Gallus gallus A0A1D5P4I6 R-GGA-9933237 https://reactome.org/PathwayBrowser/#/R-GGA-9933237 PBRM1-containing ATPase complex binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD&:PHF10 IEA Gallus gallus A0A1D5P4I6 R-GGA-9933238 https://reactome.org/PathwayBrowser/#/R-GGA-9933238 SS18-containing ATPase complex binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1:DPF1,2,3 IEA Gallus gallus A0A1D5P4I6 R-GGA-9934021 https://reactome.org/PathwayBrowser/#/R-GGA-9934021 Formation of neuronal progenitor BAF (npBAF) IEA Gallus gallus A0A1D5P4I6 R-GGA-9934024 https://reactome.org/PathwayBrowser/#/R-GGA-9934024 SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10 IEA Gallus gallus A0A1D5P4I7 R-GGA-2161282 https://reactome.org/PathwayBrowser/#/R-GGA-2161282 Elastic fibres bind associated proteins IEA Gallus gallus A0A1D5P4L5 R-GGA-114252 https://reactome.org/PathwayBrowser/#/R-GGA-114252 Cleavage of Procaspase-3 by the apoptosome IEA Gallus gallus A0A1D5P4L5 R-GGA-114254 https://reactome.org/PathwayBrowser/#/R-GGA-114254 CYCS binds to APAF1 IEA Gallus gallus A0A1D5P4L5 R-GGA-114256 https://reactome.org/PathwayBrowser/#/R-GGA-114256 CYCS:APAF1 binds procaspase-9 IEA Gallus gallus A0A1D5P4L5 R-GGA-114259 https://reactome.org/PathwayBrowser/#/R-GGA-114259 Cleavage of Procaspase‑9 to caspase‑9 IEA Gallus gallus A0A1D5P4L5 R-GGA-114261 https://reactome.org/PathwayBrowser/#/R-GGA-114261 Cleavage of Procaspase-7 by the apoptosome IEA Gallus gallus A0A1D5P4L5 R-GGA-114284 https://reactome.org/PathwayBrowser/#/R-GGA-114284 Release of Cytochrome c from mitochondria IEA Gallus gallus A0A1D5P4L5 R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus A0A1D5P4L5 R-GGA-164651 https://reactome.org/PathwayBrowser/#/R-GGA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Gallus gallus A0A1D5P4L5 R-GGA-3341294 https://reactome.org/PathwayBrowser/#/R-GGA-3341294 Superoxide reduces cytochrome c IEA Gallus gallus A0A1D5P4L5 R-GGA-5688294 https://reactome.org/PathwayBrowser/#/R-GGA-5688294 SIRT5 deacetylates Cytochrome C IEA Gallus gallus A0A1D5P4L5 R-GGA-6804596 https://reactome.org/PathwayBrowser/#/R-GGA-6804596 APAF1:CYCS binds APIP IEA Gallus gallus A0A1D5P4L5 R-GGA-9627056 https://reactome.org/PathwayBrowser/#/R-GGA-9627056 Procaspase 9 forms dimer IEA Gallus gallus A0A1D5P4L5 R-GGA-9627078 https://reactome.org/PathwayBrowser/#/R-GGA-9627078 XIAP binds CASP9 IEA Gallus gallus A0A1D5P4L5 R-GGA-9627089 https://reactome.org/PathwayBrowser/#/R-GGA-9627089 CASP9 is phosphorylated at T412 IEA Gallus gallus A0A1D5P4L5 R-GGA-9866217 https://reactome.org/PathwayBrowser/#/R-GGA-9866217 HCCS inserts heme into cytochrome c IEA Gallus gallus A0A1D5P4P4 R-GGA-4420107 https://reactome.org/PathwayBrowser/#/R-GGA-4420107 p-6Y-VEGFR2 binds SHC-transforming protein 2 IEA Gallus gallus A0A1D5P4P4 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5P4P4 R-GGA-5685366 https://reactome.org/PathwayBrowser/#/R-GGA-5685366 GRB2-1:SOS1 binds p-Y-SHC IEA Gallus gallus A0A1D5P4P8 R-GGA-2529015 https://reactome.org/PathwayBrowser/#/R-GGA-2529015 Dephosphorylation of CK2-modified condensin I IEA Gallus gallus A0A1D5P4Q4 R-GGA-1168633 https://reactome.org/PathwayBrowser/#/R-GGA-1168633 NF-kappaB translocates from the cytosol to the nucleus IEA Gallus gallus A0A1D5P4Q4 R-GGA-1168640 https://reactome.org/PathwayBrowser/#/R-GGA-1168640 Ubiquitinated IkB is degraded IEA Gallus gallus A0A1D5P4Q4 R-GGA-1168642 https://reactome.org/PathwayBrowser/#/R-GGA-1168642 SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB IEA Gallus gallus A0A1D5P4Q4 R-GGA-1168643 https://reactome.org/PathwayBrowser/#/R-GGA-1168643 SCF-beta-TrCP ubiquitinylates IkB IEA Gallus gallus A0A1D5P4Q4 R-GGA-168166 https://reactome.org/PathwayBrowser/#/R-GGA-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Gallus gallus A0A1D5P4Q4 R-GGA-193691 https://reactome.org/PathwayBrowser/#/R-GGA-193691 NF-kB migrates to the nucleus and turns on transcription IEA Gallus gallus A0A1D5P4Q4 R-GGA-193700 https://reactome.org/PathwayBrowser/#/R-GGA-193700 p75NTR ICD signals to NF-kB IEA Gallus gallus A0A1D5P4Q4 R-GGA-193705 https://reactome.org/PathwayBrowser/#/R-GGA-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate IEA Gallus gallus A0A1D5P4Q4 R-GGA-209061 https://reactome.org/PathwayBrowser/#/R-GGA-209061 Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex IEA Gallus gallus A0A1D5P4Q4 R-GGA-209063 https://reactome.org/PathwayBrowser/#/R-GGA-209063 Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex IEA Gallus gallus A0A1D5P4Q4 R-GGA-209125 https://reactome.org/PathwayBrowser/#/R-GGA-209125 SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex IEA Gallus gallus A0A1D5P4Q4 R-GGA-2730894 https://reactome.org/PathwayBrowser/#/R-GGA-2730894 NFKB1:RELA translocates from the cytosol to the nucleus IEA Gallus gallus A0A1D5P4Q4 R-GGA-4755536 https://reactome.org/PathwayBrowser/#/R-GGA-4755536 PIAS3 SUMOylates RELA with SUMO3 IEA Gallus gallus A0A1D5P4Q4 R-GGA-5607724 https://reactome.org/PathwayBrowser/#/R-GGA-5607724 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex IEA Gallus gallus A0A1D5P4Q4 R-GGA-5607728 https://reactome.org/PathwayBrowser/#/R-GGA-5607728 beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex IEA Gallus gallus A0A1D5P4Q4 R-GGA-5624473 https://reactome.org/PathwayBrowser/#/R-GGA-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit IEA Gallus gallus A0A1D5P4Q4 R-GGA-5660660 https://reactome.org/PathwayBrowser/#/R-GGA-5660660 p300 acetylates RELA subunit IEA Gallus gallus A0A1D5P4Q4 R-GGA-5660666 https://reactome.org/PathwayBrowser/#/R-GGA-5660666 CBP and p300 binds NF-kB complex IEA Gallus gallus A0A1D5P4Q4 R-GGA-8865237 https://reactome.org/PathwayBrowser/#/R-GGA-8865237 SETD6 methylates RELA in the NFkB complex IEA Gallus gallus A0A1D5P4Q4 R-GGA-9604480 https://reactome.org/PathwayBrowser/#/R-GGA-9604480 NFkB complex translocates from the cytosol to the nucleus IEA Gallus gallus A0A1D5P4Q4 R-GGA-9630923 https://reactome.org/PathwayBrowser/#/R-GGA-9630923 NF-kappa-B inhibitor binds NF-kappa-B complex IEA Gallus gallus A0A1D5P4Q4 R-GGA-9861486 https://reactome.org/PathwayBrowser/#/R-GGA-9861486 PTK2 (FAK) and Gq/11 enhance the degradation of NFKBIA (IkBalpha), phosphorylation of RELA (p65) on serine-536, and translocation of p-S536-RELA:NFKB1 (p65:p50) to the nucleus IEA Gallus gallus A0A1D5P4Q6 R-GGA-5696872 https://reactome.org/PathwayBrowser/#/R-GGA-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Gallus gallus A0A1D5P4Q6 R-GGA-74730 https://reactome.org/PathwayBrowser/#/R-GGA-74730 Insulin degradation IEA Gallus gallus A0A1D5P4Q6 R-GGA-9033235 https://reactome.org/PathwayBrowser/#/R-GGA-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1D5P4Q6 R-GGA-9033236 https://reactome.org/PathwayBrowser/#/R-GGA-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Gallus gallus A0A1D5P4R2 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus A0A1D5P4S0 R-GGA-1369028 https://reactome.org/PathwayBrowser/#/R-GGA-1369028 ABCAs mediate lipid efflux IEA Gallus gallus A0A1D5P4S0 R-GGA-1369052 https://reactome.org/PathwayBrowser/#/R-GGA-1369052 ABCAs mediate lipid influx IEA Gallus gallus A0A1D5P4S8 R-GGA-70467 https://reactome.org/PathwayBrowser/#/R-GGA-70467 PFK tetramer phosphorylates Fru(6)P IEA Gallus gallus A0A1D5P4T1 R-GGA-9856465 https://reactome.org/PathwayBrowser/#/R-GGA-9856465 MLPH/MYRIP bind GGC-RAB27A and MYO5A IEA Gallus gallus A0A1D5P4U8 R-GGA-1226094 https://reactome.org/PathwayBrowser/#/R-GGA-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Gallus gallus A0A1D5P4U8 R-GGA-1227670 https://reactome.org/PathwayBrowser/#/R-GGA-1227670 Recruitment of HDAC1 by p130 (RBL2) IEA Gallus gallus A0A1D5P4U8 R-GGA-1362261 https://reactome.org/PathwayBrowser/#/R-GGA-1362261 p130 (RBL2) associates with MuvB to form DREAM complex IEA Gallus gallus A0A1D5P4U8 R-GGA-1363303 https://reactome.org/PathwayBrowser/#/R-GGA-1363303 p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 IEA Gallus gallus A0A1D5P4U9 R-GGA-2022860 https://reactome.org/PathwayBrowser/#/R-GGA-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Gallus gallus A0A1D5P4U9 R-GGA-2022887 https://reactome.org/PathwayBrowser/#/R-GGA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Gallus gallus A0A1D5P4V9 R-GGA-156808 https://reactome.org/PathwayBrowser/#/R-GGA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Gallus gallus A0A1D5P4V9 R-GGA-157849 https://reactome.org/PathwayBrowser/#/R-GGA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Gallus gallus A0A1D5P4V9 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1D5P4V9 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus A0A1D5P4V9 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1D5P4V9 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1D5P4V9 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1D5P4V9 R-GGA-72676 https://reactome.org/PathwayBrowser/#/R-GGA-72676 eIF3 and eIF1A bind to the 40S subunit IEA Gallus gallus A0A1D5P4V9 R-GGA-72691 https://reactome.org/PathwayBrowser/#/R-GGA-72691 Formation of the 43S pre-initiation complex IEA Gallus gallus A0A1D5P4V9 R-GGA-72697 https://reactome.org/PathwayBrowser/#/R-GGA-72697 Start codon recognition IEA Gallus gallus A0A1D5P4V9 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1D5P4V9 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5P4V9 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5P4W0 R-GGA-9624845 https://reactome.org/PathwayBrowser/#/R-GGA-9624845 RCC1 stimulates GDP to GTP exchange on RAN IEA Gallus gallus A0A1D5P4W1 R-GGA-8854173 https://reactome.org/PathwayBrowser/#/R-GGA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Gallus gallus A0A1D5P4X2 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5P4X2 R-GGA-6809011 https://reactome.org/PathwayBrowser/#/R-GGA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Gallus gallus A0A1D5P4X2 R-GGA-6811431 https://reactome.org/PathwayBrowser/#/R-GGA-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Gallus gallus A0A1D5P4X2 R-GGA-6811433 https://reactome.org/PathwayBrowser/#/R-GGA-6811433 The COG tethering complex interacts with numerous SNAREs at the Golgi membrane IEA Gallus gallus A0A1D5P4X2 R-GGA-6814682 https://reactome.org/PathwayBrowser/#/R-GGA-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Gallus gallus A0A1D5P4X2 R-GGA-8849748 https://reactome.org/PathwayBrowser/#/R-GGA-8849748 The COG complex binds RABs at the Golgi membrane IEA Gallus gallus A0A1D5P4Z9 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5P4Z9 R-GGA-5336182 https://reactome.org/PathwayBrowser/#/R-GGA-5336182 GPR37 binds prosaptide IEA Gallus gallus A0A1D5P4Z9 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5P4Z9 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5P532 R-GGA-8850326 https://reactome.org/PathwayBrowser/#/R-GGA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Gallus gallus A0A1D5P532 R-GGA-8850356 https://reactome.org/PathwayBrowser/#/R-GGA-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Gallus gallus A0A1D5P546 R-GGA-1022127 https://reactome.org/PathwayBrowser/#/R-GGA-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Gallus gallus A0A1D5P546 R-GGA-110307 https://reactome.org/PathwayBrowser/#/R-GGA-110307 REV1 binds AP-dsDNA IEA Gallus gallus A0A1D5P546 R-GGA-110308 https://reactome.org/PathwayBrowser/#/R-GGA-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Gallus gallus A0A1D5P546 R-GGA-110311 https://reactome.org/PathwayBrowser/#/R-GGA-110311 POLZ extends translesion synthesis IEA Gallus gallus A0A1D5P546 R-GGA-110316 https://reactome.org/PathwayBrowser/#/R-GGA-110316 POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template IEA Gallus gallus A0A1D5P546 R-GGA-110317 https://reactome.org/PathwayBrowser/#/R-GGA-110317 Insertion of correct bases opposite the lesion by POLH IEA Gallus gallus A0A1D5P546 R-GGA-110319 https://reactome.org/PathwayBrowser/#/R-GGA-110319 Elongation by POLH IEA Gallus gallus A0A1D5P546 R-GGA-1168643 https://reactome.org/PathwayBrowser/#/R-GGA-1168643 SCF-beta-TrCP ubiquitinylates IkB IEA Gallus gallus A0A1D5P546 R-GGA-1234159 https://reactome.org/PathwayBrowser/#/R-GGA-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Gallus gallus A0A1D5P546 R-GGA-1234163 https://reactome.org/PathwayBrowser/#/R-GGA-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Gallus gallus A0A1D5P546 R-GGA-1234172 https://reactome.org/PathwayBrowser/#/R-GGA-1234172 Nuclear VBC complex ubiquitinylates HIF-alpha IEA Gallus gallus A0A1D5P546 R-GGA-1234175 https://reactome.org/PathwayBrowser/#/R-GGA-1234175 ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol IEA Gallus gallus A0A1D5P546 R-GGA-1253282 https://reactome.org/PathwayBrowser/#/R-GGA-1253282 ERBB4 ubiquitination by WWP1/ITCH IEA Gallus gallus A0A1D5P546 R-GGA-1295621 https://reactome.org/PathwayBrowser/#/R-GGA-1295621 CBL dissociates from ubiquitinated p-SPRY2 IEA Gallus gallus A0A1D5P546 R-GGA-1358789 https://reactome.org/PathwayBrowser/#/R-GGA-1358789 Self-ubiquitination of RNF41 IEA Gallus gallus A0A1D5P546 R-GGA-1358790 https://reactome.org/PathwayBrowser/#/R-GGA-1358790 RNF41 ubiquitinates ERBB3 IEA Gallus gallus A0A1D5P546 R-GGA-1358792 https://reactome.org/PathwayBrowser/#/R-GGA-1358792 RNF41 ubiquitinates activated ERBB3 IEA Gallus gallus A0A1D5P546 R-GGA-1358795 https://reactome.org/PathwayBrowser/#/R-GGA-1358795 Deubiquitination of RNF41 by P-USP8 IEA Gallus gallus A0A1D5P546 R-GGA-1358797 https://reactome.org/PathwayBrowser/#/R-GGA-1358797 Ubiquitinated RNF41 binds P-USP8 IEA Gallus gallus A0A1D5P546 R-GGA-1363331 https://reactome.org/PathwayBrowser/#/R-GGA-1363331 Ubiquitination of p130 (RBL2) by SCF (Skp2) IEA Gallus gallus A0A1D5P546 R-GGA-1504190 https://reactome.org/PathwayBrowser/#/R-GGA-1504190 DVL is ubiquitinated by CUL3:KLHL12:RBX1 IEA Gallus gallus A0A1D5P546 R-GGA-1504193 https://reactome.org/PathwayBrowser/#/R-GGA-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Gallus gallus A0A1D5P546 R-GGA-168915 https://reactome.org/PathwayBrowser/#/R-GGA-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex IEA Gallus gallus A0A1D5P546 R-GGA-173542 https://reactome.org/PathwayBrowser/#/R-GGA-173542 SMURF2 ubiquitinates SMAD2 IEA Gallus gallus A0A1D5P546 R-GGA-174057 https://reactome.org/PathwayBrowser/#/R-GGA-174057 Multiubiquitination of APC/C-associated Cdh1 IEA Gallus gallus A0A1D5P546 R-GGA-174058 https://reactome.org/PathwayBrowser/#/R-GGA-174058 Degradation of multiubiquitinated Cdh1 IEA Gallus gallus A0A1D5P546 R-GGA-174104 https://reactome.org/PathwayBrowser/#/R-GGA-174104 Ubiquitination of Cyclin A by APC/C:Cdc20 complex IEA Gallus gallus A0A1D5P546 R-GGA-174105 https://reactome.org/PathwayBrowser/#/R-GGA-174105 Degradation of multiubiquitinated cell cycle proteins IEA Gallus gallus A0A1D5P546 R-GGA-174144 https://reactome.org/PathwayBrowser/#/R-GGA-174144 Ubiquitination of Securin by phospho-APC/C:Cdc20 complex IEA Gallus gallus A0A1D5P546 R-GGA-174157 https://reactome.org/PathwayBrowser/#/R-GGA-174157 Degradation of multiubiquitinated Cyclin B IEA Gallus gallus A0A1D5P546 R-GGA-174159 https://reactome.org/PathwayBrowser/#/R-GGA-174159 Ubiquitination of Emi1 by SCF-beta-TrCP IEA Gallus gallus A0A1D5P546 R-GGA-174195 https://reactome.org/PathwayBrowser/#/R-GGA-174195 Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex IEA Gallus gallus A0A1D5P546 R-GGA-174202 https://reactome.org/PathwayBrowser/#/R-GGA-174202 Degradation of multiubiquitinated Securin IEA Gallus gallus A0A1D5P546 R-GGA-174227 https://reactome.org/PathwayBrowser/#/R-GGA-174227 Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex IEA Gallus gallus A0A1D5P546 R-GGA-174255 https://reactome.org/PathwayBrowser/#/R-GGA-174255 Degradation multiubiquitinated Cyclin A IEA Gallus gallus A0A1D5P546 R-GGA-179417 https://reactome.org/PathwayBrowser/#/R-GGA-179417 Multiubiquitination of Nek2A IEA Gallus gallus A0A1D5P546 R-GGA-179421 https://reactome.org/PathwayBrowser/#/R-GGA-179421 Degradation of multiubiquitinated Nek2A IEA Gallus gallus A0A1D5P546 R-GGA-182986 https://reactome.org/PathwayBrowser/#/R-GGA-182986 CBL-mediated ubiquitination of CIN85 IEA Gallus gallus A0A1D5P546 R-GGA-182993 https://reactome.org/PathwayBrowser/#/R-GGA-182993 Ubiquitination of stimulated EGFR (CBL) IEA Gallus gallus A0A1D5P546 R-GGA-183036 https://reactome.org/PathwayBrowser/#/R-GGA-183036 Ubiquitination of stimulated EGFR (CBL:GRB2) IEA Gallus gallus A0A1D5P546 R-GGA-183051 https://reactome.org/PathwayBrowser/#/R-GGA-183051 CBL ubiquitinates Sprouty IEA Gallus gallus A0A1D5P546 R-GGA-183084 https://reactome.org/PathwayBrowser/#/R-GGA-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Gallus gallus A0A1D5P546 R-GGA-183089 https://reactome.org/PathwayBrowser/#/R-GGA-183089 CBL binds and ubiquitinates phosphorylated Sprouty IEA Gallus gallus A0A1D5P546 R-GGA-187574 https://reactome.org/PathwayBrowser/#/R-GGA-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Gallus gallus A0A1D5P546 R-GGA-187575 https://reactome.org/PathwayBrowser/#/R-GGA-187575 Ubiquitination of phospho-p27/p21 IEA Gallus gallus A0A1D5P546 R-GGA-188191 https://reactome.org/PathwayBrowser/#/R-GGA-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Gallus gallus A0A1D5P546 R-GGA-1912357 https://reactome.org/PathwayBrowser/#/R-GGA-1912357 ITCH ubiquitinates DTX IEA Gallus gallus A0A1D5P546 R-GGA-1918092 https://reactome.org/PathwayBrowser/#/R-GGA-1918092 CHIP (STUB1) mediates ubiquitination of ERBB2 IEA Gallus gallus A0A1D5P546 R-GGA-1918095 https://reactome.org/PathwayBrowser/#/R-GGA-1918095 CUL5 mediates ubiquitination of ERBB2 IEA Gallus gallus A0A1D5P546 R-GGA-1977296 https://reactome.org/PathwayBrowser/#/R-GGA-1977296 NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer IEA Gallus gallus A0A1D5P546 R-GGA-204947 https://reactome.org/PathwayBrowser/#/R-GGA-204947 Polyubiquitinated NRIF migrates to the nucleus IEA Gallus gallus A0A1D5P546 R-GGA-205008 https://reactome.org/PathwayBrowser/#/R-GGA-205008 Polyubiquitinated NRIF binds to p62 (Sequestosome) IEA Gallus gallus A0A1D5P546 R-GGA-205118 https://reactome.org/PathwayBrowser/#/R-GGA-205118 TRAF6 polyubiquitinates NRIF IEA Gallus gallus A0A1D5P546 R-GGA-209061 https://reactome.org/PathwayBrowser/#/R-GGA-209061 Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex IEA Gallus gallus A0A1D5P546 R-GGA-209063 https://reactome.org/PathwayBrowser/#/R-GGA-209063 Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex IEA Gallus gallus A0A1D5P546 R-GGA-209536 https://reactome.org/PathwayBrowser/#/R-GGA-209536 IkB is ubiquitinated and degraded IEA Gallus gallus A0A1D5P546 R-GGA-209566 https://reactome.org/PathwayBrowser/#/R-GGA-209566 TRAF6 is auto-ubiquitinated IEA Gallus gallus A0A1D5P546 R-GGA-2130282 https://reactome.org/PathwayBrowser/#/R-GGA-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Gallus gallus A0A1D5P546 R-GGA-2130286 https://reactome.org/PathwayBrowser/#/R-GGA-2130286 Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) IEA Gallus gallus A0A1D5P546 R-GGA-2160931 https://reactome.org/PathwayBrowser/#/R-GGA-2160931 Disassembly of tight junctions IEA Gallus gallus A0A1D5P546 R-GGA-2169046 https://reactome.org/PathwayBrowser/#/R-GGA-2169046 Degradation of TGF-beta receptor complex IEA Gallus gallus A0A1D5P546 R-GGA-2176452 https://reactome.org/PathwayBrowser/#/R-GGA-2176452 Degradation of ubiquitinated SMAD2 IEA Gallus gallus A0A1D5P546 R-GGA-2176502 https://reactome.org/PathwayBrowser/#/R-GGA-2176502 NEDD4L ubiquitinates SMAD2/3 IEA Gallus gallus A0A1D5P546 R-GGA-2176503 https://reactome.org/PathwayBrowser/#/R-GGA-2176503 Degradation of SMAD2/3:SMAD4 complex IEA Gallus gallus A0A1D5P546 R-GGA-2186767 https://reactome.org/PathwayBrowser/#/R-GGA-2186767 Degradation of ubiquitinated SKI/SKIL IEA Gallus gallus A0A1D5P546 R-GGA-2186780 https://reactome.org/PathwayBrowser/#/R-GGA-2186780 Degradation of Ub-SMAD7 IEA Gallus gallus A0A1D5P546 R-GGA-2187368 https://reactome.org/PathwayBrowser/#/R-GGA-2187368 STUB1 (CHIP) ubiquitinates SMAD3 IEA Gallus gallus A0A1D5P546 R-GGA-2187382 https://reactome.org/PathwayBrowser/#/R-GGA-2187382 Degradation of ubiquitinated SMAD3 IEA Gallus gallus A0A1D5P546 R-GGA-2213017 https://reactome.org/PathwayBrowser/#/R-GGA-2213017 Auto-ubiquitination of TRAF3 IEA Gallus gallus A0A1D5P546 R-GGA-264444 https://reactome.org/PathwayBrowser/#/R-GGA-264444 Autoubiquitination of phospho-COP1(Ser-387 ) IEA Gallus gallus A0A1D5P546 R-GGA-264458 https://reactome.org/PathwayBrowser/#/R-GGA-264458 Proteasome mediated degradation of COP1 IEA Gallus gallus A0A1D5P546 R-GGA-2682349 https://reactome.org/PathwayBrowser/#/R-GGA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Gallus gallus A0A1D5P546 R-GGA-3000335 https://reactome.org/PathwayBrowser/#/R-GGA-3000335 SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA IEA Gallus gallus A0A1D5P546 R-GGA-3134946 https://reactome.org/PathwayBrowser/#/R-GGA-3134946 DDX41 ubiquitination by TRIM21 IEA Gallus gallus A0A1D5P546 R-GGA-3322429 https://reactome.org/PathwayBrowser/#/R-GGA-3322429 XIAP monoubiquinates TLE IEA Gallus gallus A0A1D5P546 R-GGA-3640861 https://reactome.org/PathwayBrowser/#/R-GGA-3640861 RNF146 ubiquitinates ADP-ribosylated AXIN IEA Gallus gallus A0A1D5P546 R-GGA-3640872 https://reactome.org/PathwayBrowser/#/R-GGA-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Gallus gallus A0A1D5P546 R-GGA-3640874 https://reactome.org/PathwayBrowser/#/R-GGA-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5P546 R-GGA-3788724 https://reactome.org/PathwayBrowser/#/R-GGA-3788724 Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 IEA Gallus gallus A0A1D5P546 R-GGA-450337 https://reactome.org/PathwayBrowser/#/R-GGA-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Gallus gallus A0A1D5P546 R-GGA-450346 https://reactome.org/PathwayBrowser/#/R-GGA-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Gallus gallus A0A1D5P546 R-GGA-450358 https://reactome.org/PathwayBrowser/#/R-GGA-450358 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation IEA Gallus gallus A0A1D5P546 R-GGA-450580 https://reactome.org/PathwayBrowser/#/R-GGA-450580 AUF1 (hnRNP D0) is ubiquitinylated IEA Gallus gallus A0A1D5P546 R-GGA-4641129 https://reactome.org/PathwayBrowser/#/R-GGA-4641129 AXIN is ubiquitinated by SMURF2 IEA Gallus gallus A0A1D5P546 R-GGA-4641236 https://reactome.org/PathwayBrowser/#/R-GGA-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Gallus gallus A0A1D5P546 R-GGA-4641246 https://reactome.org/PathwayBrowser/#/R-GGA-4641246 ZNRF3 autoubiquitinates to promote its internalization IEA Gallus gallus A0A1D5P546 R-GGA-4641253 https://reactome.org/PathwayBrowser/#/R-GGA-4641253 ZNRF3 ubiquitinates FZD to promote its downregulation IEA Gallus gallus A0A1D5P546 R-GGA-4641256 https://reactome.org/PathwayBrowser/#/R-GGA-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5P546 R-GGA-5357757 https://reactome.org/PathwayBrowser/#/R-GGA-5357757 BIRC(cIAP1/2) ubiquitinates RIPK1 IEA Gallus gallus A0A1D5P546 R-GGA-5357845 https://reactome.org/PathwayBrowser/#/R-GGA-5357845 K63polyUb-RIPK1 is deubiquitinated IEA Gallus gallus A0A1D5P546 R-GGA-5362412 https://reactome.org/PathwayBrowser/#/R-GGA-5362412 SYVN1 ubiquitinates Hh C-terminal fragments IEA Gallus gallus A0A1D5P546 R-GGA-5362448 https://reactome.org/PathwayBrowser/#/R-GGA-5362448 Hh C-terminal fragments are degraded by the proteasome IEA Gallus gallus A0A1D5P546 R-GGA-5362500 https://reactome.org/PathwayBrowser/#/R-GGA-5362500 TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Gallus gallus A0A1D5P546 R-GGA-5607728 https://reactome.org/PathwayBrowser/#/R-GGA-5607728 beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex IEA Gallus gallus A0A1D5P546 R-GGA-5610742 https://reactome.org/PathwayBrowser/#/R-GGA-5610742 SCF(beta-TrCP) ubiquitinates p-GLI1 IEA Gallus gallus A0A1D5P546 R-GGA-5610746 https://reactome.org/PathwayBrowser/#/R-GGA-5610746 SCF(beta-TrCP) ubiquitinates p-GLI3 IEA Gallus gallus A0A1D5P546 R-GGA-5635854 https://reactome.org/PathwayBrowser/#/R-GGA-5635854 GLI2,3 are degraded by the proteasome IEA Gallus gallus A0A1D5P546 R-GGA-5635856 https://reactome.org/PathwayBrowser/#/R-GGA-5635856 SPOP:CUL3:RBX1 ubiquitinates GLI2,3 IEA Gallus gallus A0A1D5P546 R-GGA-5635864 https://reactome.org/PathwayBrowser/#/R-GGA-5635864 NUMB:ITCH ubiquitinates GLI1 IEA Gallus gallus A0A1D5P546 R-GGA-5635868 https://reactome.org/PathwayBrowser/#/R-GGA-5635868 ub-GLI is degraded by the proteasome IEA Gallus gallus A0A1D5P546 R-GGA-5652009 https://reactome.org/PathwayBrowser/#/R-GGA-5652009 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA IEA Gallus gallus A0A1D5P546 R-GGA-5652151 https://reactome.org/PathwayBrowser/#/R-GGA-5652151 REV1 recruits POLZ to (AP:Cyt)-DNA Template IEA Gallus gallus A0A1D5P546 R-GGA-5653756 https://reactome.org/PathwayBrowser/#/R-GGA-5653756 TRIM25 binds monoUb:164-PCNA IEA Gallus gallus A0A1D5P546 R-GGA-5653766 https://reactome.org/PathwayBrowser/#/R-GGA-5653766 USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Gallus gallus A0A1D5P546 R-GGA-5653770 https://reactome.org/PathwayBrowser/#/R-GGA-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Gallus gallus A0A1D5P546 R-GGA-5653838 https://reactome.org/PathwayBrowser/#/R-GGA-5653838 POLD,POLE binds deISGylated PCNA after TLS IEA Gallus gallus A0A1D5P546 R-GGA-5654672 https://reactome.org/PathwayBrowser/#/R-GGA-5654672 CBL ubiquitinates FRS2 and FGFR1 IEA Gallus gallus A0A1D5P546 R-GGA-5654677 https://reactome.org/PathwayBrowser/#/R-GGA-5654677 CBL ubiquitinates FRS2 and FGFR2 IEA Gallus gallus A0A1D5P546 R-GGA-5654679 https://reactome.org/PathwayBrowser/#/R-GGA-5654679 CBL ubiquitinates FRS2 and FGFR3 IEA Gallus gallus A0A1D5P546 R-GGA-5654684 https://reactome.org/PathwayBrowser/#/R-GGA-5654684 CBL ubiquitinates FRS2 and FGFR4 IEA Gallus gallus A0A1D5P546 R-GGA-5654985 https://reactome.org/PathwayBrowser/#/R-GGA-5654985 SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH IEA Gallus gallus A0A1D5P546 R-GGA-5654986 https://reactome.org/PathwayBrowser/#/R-GGA-5654986 SPRTN binds monoUb:K164-PCNA associated with POLH IEA Gallus gallus A0A1D5P546 R-GGA-5654989 https://reactome.org/PathwayBrowser/#/R-GGA-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Gallus gallus A0A1D5P546 R-GGA-5655170 https://reactome.org/PathwayBrowser/#/R-GGA-5655170 RCHY1 monoubiquitinates POLH IEA Gallus gallus A0A1D5P546 R-GGA-5655193 https://reactome.org/PathwayBrowser/#/R-GGA-5655193 KIAA0101 double monoubiquitination IEA Gallus gallus A0A1D5P546 R-GGA-5655466 https://reactome.org/PathwayBrowser/#/R-GGA-5655466 USP1:WDR48 deubiquitinates monoUb:K164-PCNA IEA Gallus gallus A0A1D5P546 R-GGA-5655481 https://reactome.org/PathwayBrowser/#/R-GGA-5655481 USP1:WDR48 binds monoUb:K164-PCNA IEA Gallus gallus A0A1D5P546 R-GGA-5655835 https://reactome.org/PathwayBrowser/#/R-GGA-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Gallus gallus A0A1D5P546 R-GGA-5655892 https://reactome.org/PathwayBrowser/#/R-GGA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Gallus gallus A0A1D5P546 R-GGA-5655965 https://reactome.org/PathwayBrowser/#/R-GGA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Gallus gallus A0A1D5P546 R-GGA-5656148 https://reactome.org/PathwayBrowser/#/R-GGA-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Gallus gallus A0A1D5P546 R-GGA-5656158 https://reactome.org/PathwayBrowser/#/R-GGA-5656158 POLZ elongates POLI-incorporated dNMP IEA Gallus gallus A0A1D5P546 R-GGA-5668414 https://reactome.org/PathwayBrowser/#/R-GGA-5668414 TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK IEA Gallus gallus A0A1D5P546 R-GGA-5668454 https://reactome.org/PathwayBrowser/#/R-GGA-5668454 K63polyUb-cIAP1,2 ubiquitinates TRAF3 IEA Gallus gallus A0A1D5P546 R-GGA-5668534 https://reactome.org/PathwayBrowser/#/R-GGA-5668534 cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK IEA Gallus gallus A0A1D5P546 R-GGA-5674022 https://reactome.org/PathwayBrowser/#/R-GGA-5674022 BRAP autoubiquitinates IEA Gallus gallus A0A1D5P546 R-GGA-5675470 https://reactome.org/PathwayBrowser/#/R-GGA-5675470 BIRC2/3 (cIAP1/2) is autoubiquitinated IEA Gallus gallus A0A1D5P546 R-GGA-5682858 https://reactome.org/PathwayBrowser/#/R-GGA-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Gallus gallus A0A1D5P546 R-GGA-5683077 https://reactome.org/PathwayBrowser/#/R-GGA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Gallus gallus A0A1D5P546 R-GGA-5684250 https://reactome.org/PathwayBrowser/#/R-GGA-5684250 SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 IEA Gallus gallus A0A1D5P546 R-GGA-5684273 https://reactome.org/PathwayBrowser/#/R-GGA-5684273 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 IEA Gallus gallus A0A1D5P546 R-GGA-5687112 https://reactome.org/PathwayBrowser/#/R-GGA-5687112 MAPK6 is degraded by the 26S proteasome IEA Gallus gallus A0A1D5P546 R-GGA-5688797 https://reactome.org/PathwayBrowser/#/R-GGA-5688797 ATXN3 family cleave Ub chains IEA Gallus gallus A0A1D5P546 R-GGA-5688837 https://reactome.org/PathwayBrowser/#/R-GGA-5688837 ATXN3 deubiquitinates polyUb-PARK2 IEA Gallus gallus A0A1D5P546 R-GGA-5689111 https://reactome.org/PathwayBrowser/#/R-GGA-5689111 PARK2 autoubiquitinates IEA Gallus gallus A0A1D5P546 R-GGA-5689861 https://reactome.org/PathwayBrowser/#/R-GGA-5689861 Recruitment of XPA and release of CAK IEA Gallus gallus A0A1D5P546 R-GGA-5690152 https://reactome.org/PathwayBrowser/#/R-GGA-5690152 USP5 cleaves polyubiquitin IEA Gallus gallus A0A1D5P546 R-GGA-5690157 https://reactome.org/PathwayBrowser/#/R-GGA-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Gallus gallus A0A1D5P546 R-GGA-5690196 https://reactome.org/PathwayBrowser/#/R-GGA-5690196 USP8 deubiquitinates RNF128 IEA Gallus gallus A0A1D5P546 R-GGA-5690213 https://reactome.org/PathwayBrowser/#/R-GGA-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Gallus gallus A0A1D5P546 R-GGA-5690319 https://reactome.org/PathwayBrowser/#/R-GGA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Gallus gallus A0A1D5P546 R-GGA-5690790 https://reactome.org/PathwayBrowser/#/R-GGA-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Gallus gallus A0A1D5P546 R-GGA-5690827 https://reactome.org/PathwayBrowser/#/R-GGA-5690827 TNFAIP3 (A20) ubiquitinates RIPK1 IEA Gallus gallus A0A1D5P546 R-GGA-5690856 https://reactome.org/PathwayBrowser/#/R-GGA-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Gallus gallus A0A1D5P546 R-GGA-5690870 https://reactome.org/PathwayBrowser/#/R-GGA-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Gallus gallus A0A1D5P546 R-GGA-5690996 https://reactome.org/PathwayBrowser/#/R-GGA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Gallus gallus A0A1D5P546 R-GGA-5691000 https://reactome.org/PathwayBrowser/#/R-GGA-5691000 TFIIH binds GG-NER site to form a verification complex IEA Gallus gallus A0A1D5P546 R-GGA-5691001 https://reactome.org/PathwayBrowser/#/R-GGA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Gallus gallus A0A1D5P546 R-GGA-5691108 https://reactome.org/PathwayBrowser/#/R-GGA-5691108 SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 IEA Gallus gallus A0A1D5P546 R-GGA-5691381 https://reactome.org/PathwayBrowser/#/R-GGA-5691381 MYSM1 deubiquitinates Histone H2A IEA Gallus gallus A0A1D5P546 R-GGA-5691431 https://reactome.org/PathwayBrowser/#/R-GGA-5691431 PSMD14 cleaves K63-linked ubiquitin IEA Gallus gallus A0A1D5P546 R-GGA-5691439 https://reactome.org/PathwayBrowser/#/R-GGA-5691439 BRISC complex deubiquitinates NLRP3 IEA Gallus gallus A0A1D5P546 R-GGA-5693108 https://reactome.org/PathwayBrowser/#/R-GGA-5693108 TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains IEA Gallus gallus A0A1D5P546 R-GGA-5693593 https://reactome.org/PathwayBrowser/#/R-GGA-5693593 D-loop extension by DNA polymerases IEA Gallus gallus A0A1D5P546 R-GGA-5696534 https://reactome.org/PathwayBrowser/#/R-GGA-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Gallus gallus A0A1D5P546 R-GGA-5696547 https://reactome.org/PathwayBrowser/#/R-GGA-5696547 STAMBPL1 is a deubiquitinase IEA Gallus gallus A0A1D5P546 R-GGA-5696627 https://reactome.org/PathwayBrowser/#/R-GGA-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Gallus gallus A0A1D5P546 R-GGA-5696655 https://reactome.org/PathwayBrowser/#/R-GGA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Gallus gallus A0A1D5P546 R-GGA-5696664 https://reactome.org/PathwayBrowser/#/R-GGA-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Gallus gallus A0A1D5P546 R-GGA-5696670 https://reactome.org/PathwayBrowser/#/R-GGA-5696670 CHD1L is recruited to GG-NER site IEA Gallus gallus A0A1D5P546 R-GGA-5696872 https://reactome.org/PathwayBrowser/#/R-GGA-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Gallus gallus A0A1D5P546 R-GGA-5696945 https://reactome.org/PathwayBrowser/#/R-GGA-5696945 USP33 deubiquitinates CCP110,ARRB IEA Gallus gallus A0A1D5P546 R-GGA-5696960 https://reactome.org/PathwayBrowser/#/R-GGA-5696960 USP49 deubiquitinates H2B IEA Gallus gallus A0A1D5P546 R-GGA-5696968 https://reactome.org/PathwayBrowser/#/R-GGA-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Gallus gallus A0A1D5P546 R-GGA-6781764 https://reactome.org/PathwayBrowser/#/R-GGA-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Gallus gallus A0A1D5P546 R-GGA-6781779 https://reactome.org/PathwayBrowser/#/R-GGA-6781779 USP13 deubiquitinates BECN1,USP10 IEA Gallus gallus A0A1D5P546 R-GGA-6781814 https://reactome.org/PathwayBrowser/#/R-GGA-6781814 USP19 deubiquitinates RNF123 IEA Gallus gallus A0A1D5P546 R-GGA-6781867 https://reactome.org/PathwayBrowser/#/R-GGA-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Gallus gallus A0A1D5P546 R-GGA-6782069 https://reactome.org/PathwayBrowser/#/R-GGA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Gallus gallus A0A1D5P546 R-GGA-6782106 https://reactome.org/PathwayBrowser/#/R-GGA-6782106 USP10 deubiquitinates SNX3, CFTR IEA Gallus gallus A0A1D5P546 R-GGA-6782131 https://reactome.org/PathwayBrowser/#/R-GGA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5P546 R-GGA-6782138 https://reactome.org/PathwayBrowser/#/R-GGA-6782138 ERCC5 and RPA bind TC-NER site IEA Gallus gallus A0A1D5P546 R-GGA-6782204 https://reactome.org/PathwayBrowser/#/R-GGA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Gallus gallus A0A1D5P546 R-GGA-6782208 https://reactome.org/PathwayBrowser/#/R-GGA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Gallus gallus A0A1D5P546 R-GGA-6782211 https://reactome.org/PathwayBrowser/#/R-GGA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Gallus gallus A0A1D5P546 R-GGA-6782227 https://reactome.org/PathwayBrowser/#/R-GGA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Gallus gallus A0A1D5P546 R-GGA-6782628 https://reactome.org/PathwayBrowser/#/R-GGA-6782628 USP8 deubiquitinates STAM2:HGS IEA Gallus gallus A0A1D5P546 R-GGA-6782943 https://reactome.org/PathwayBrowser/#/R-GGA-6782943 UV-DDB ubiquitinates XPC IEA Gallus gallus A0A1D5P546 R-GGA-6785361 https://reactome.org/PathwayBrowser/#/R-GGA-6785361 Monoubiquitination of FANCD2:FANCI IEA Gallus gallus A0A1D5P546 R-GGA-6786171 https://reactome.org/PathwayBrowser/#/R-GGA-6786171 FANCD2 deubiquitination by USP1:WDR48 IEA Gallus gallus A0A1D5P546 R-GGA-6790454 https://reactome.org/PathwayBrowser/#/R-GGA-6790454 SUMOylation of XPC IEA Gallus gallus A0A1D5P546 R-GGA-6790487 https://reactome.org/PathwayBrowser/#/R-GGA-6790487 RNF111 ubiquitinates SUMOylated XPC IEA Gallus gallus A0A1D5P546 R-GGA-6798373 https://reactome.org/PathwayBrowser/#/R-GGA-6798373 MDM2 ubiquitinates DYRK2 IEA Gallus gallus A0A1D5P546 R-GGA-6804253 https://reactome.org/PathwayBrowser/#/R-GGA-6804253 MDM2 ubiquitinates JMY IEA Gallus gallus A0A1D5P546 R-GGA-6804942 https://reactome.org/PathwayBrowser/#/R-GGA-6804942 MDM2 homodimers auto-ubiquitinate IEA Gallus gallus A0A1D5P546 R-GGA-6807106 https://reactome.org/PathwayBrowser/#/R-GGA-6807106 PTEN undergoes monoubiquitination IEA Gallus gallus A0A1D5P546 R-GGA-6807118 https://reactome.org/PathwayBrowser/#/R-GGA-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Gallus gallus A0A1D5P546 R-GGA-6807134 https://reactome.org/PathwayBrowser/#/R-GGA-6807134 NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN IEA Gallus gallus A0A1D5P546 R-GGA-6807206 https://reactome.org/PathwayBrowser/#/R-GGA-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Gallus gallus A0A1D5P546 R-GGA-68712 https://reactome.org/PathwayBrowser/#/R-GGA-68712 The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 IEA Gallus gallus A0A1D5P546 R-GGA-68825 https://reactome.org/PathwayBrowser/#/R-GGA-68825 Ubiquitinated geminin is degraded by the proteasome IEA Gallus gallus A0A1D5P546 R-GGA-68946 https://reactome.org/PathwayBrowser/#/R-GGA-68946 Phosphorylated Orc1 is ubiquitinated while still associated with chromatin IEA Gallus gallus A0A1D5P546 R-GGA-68948 https://reactome.org/PathwayBrowser/#/R-GGA-68948 Ubiquitinated Orc1 is degraded by the proteasome IEA Gallus gallus A0A1D5P546 R-GGA-69015 https://reactome.org/PathwayBrowser/#/R-GGA-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Gallus gallus A0A1D5P546 R-GGA-69016 https://reactome.org/PathwayBrowser/#/R-GGA-69016 Ubiquitinated Cdc6 is degraded by the proteasome IEA Gallus gallus A0A1D5P546 R-GGA-69600 https://reactome.org/PathwayBrowser/#/R-GGA-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Gallus gallus A0A1D5P546 R-GGA-75825 https://reactome.org/PathwayBrowser/#/R-GGA-75825 Proteasome mediated degradation of Cyclin D1 IEA Gallus gallus A0A1D5P546 R-GGA-8848829 https://reactome.org/PathwayBrowser/#/R-GGA-8848829 CBL autoubiquitinates IEA Gallus gallus A0A1D5P546 R-GGA-8850594 https://reactome.org/PathwayBrowser/#/R-GGA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Gallus gallus A0A1D5P546 R-GGA-8850992 https://reactome.org/PathwayBrowser/#/R-GGA-8850992 Proteasome degrades polyubiquitinated PTEN IEA Gallus gallus A0A1D5P546 R-GGA-8851011 https://reactome.org/PathwayBrowser/#/R-GGA-8851011 TRIM27 polyubiquitinates PTEN IEA Gallus gallus A0A1D5P546 R-GGA-8852127 https://reactome.org/PathwayBrowser/#/R-GGA-8852127 UBA6 conjugates ubiquitin to cytosolic E2 enzymes IEA Gallus gallus A0A1D5P546 R-GGA-8852128 https://reactome.org/PathwayBrowser/#/R-GGA-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Gallus gallus A0A1D5P546 R-GGA-8852129 https://reactome.org/PathwayBrowser/#/R-GGA-8852129 UBA1 conjugates ubiquitin to cytosolic E2 enzymes IEA Gallus gallus A0A1D5P546 R-GGA-8852130 https://reactome.org/PathwayBrowser/#/R-GGA-8852130 UBA1 conjugates ubiquitin to nuclear E2 enzymes IEA Gallus gallus A0A1D5P546 R-GGA-8852131 https://reactome.org/PathwayBrowser/#/R-GGA-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Gallus gallus A0A1D5P546 R-GGA-8852132 https://reactome.org/PathwayBrowser/#/R-GGA-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Gallus gallus A0A1D5P546 R-GGA-8852133 https://reactome.org/PathwayBrowser/#/R-GGA-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Gallus gallus A0A1D5P546 R-GGA-8852134 https://reactome.org/PathwayBrowser/#/R-GGA-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Gallus gallus A0A1D5P546 R-GGA-8852136 https://reactome.org/PathwayBrowser/#/R-GGA-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Gallus gallus A0A1D5P546 R-GGA-8853379 https://reactome.org/PathwayBrowser/#/R-GGA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Gallus gallus A0A1D5P546 R-GGA-8853515 https://reactome.org/PathwayBrowser/#/R-GGA-8853515 OTULIN,USP5 cleaves UBC yielding ubiquitin IEA Gallus gallus A0A1D5P546 R-GGA-8854041 https://reactome.org/PathwayBrowser/#/R-GGA-8854041 SCF-FBXL7 ubiquitinates AURKA IEA Gallus gallus A0A1D5P546 R-GGA-8854044 https://reactome.org/PathwayBrowser/#/R-GGA-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Gallus gallus A0A1D5P546 R-GGA-8854051 https://reactome.org/PathwayBrowser/#/R-GGA-8854051 SCF-FBXL18 ubiquitinates FBXL7 IEA Gallus gallus A0A1D5P546 R-GGA-8854071 https://reactome.org/PathwayBrowser/#/R-GGA-8854071 Proteasome-mediated degradation of PolyUb-FBXL7 IEA Gallus gallus A0A1D5P546 R-GGA-8854628 https://reactome.org/PathwayBrowser/#/R-GGA-8854628 MYLIP dimer ubiquitinates VLDLR on Lys-839 IEA Gallus gallus A0A1D5P546 R-GGA-8865182 https://reactome.org/PathwayBrowser/#/R-GGA-8865182 OTUD7A hydrolyses K11diUb IEA Gallus gallus A0A1D5P546 R-GGA-8866279 https://reactome.org/PathwayBrowser/#/R-GGA-8866279 Epsin family proteins bind ubiquitinated cargo IEA Gallus gallus A0A1D5P546 R-GGA-8866542 https://reactome.org/PathwayBrowser/#/R-GGA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Gallus gallus A0A1D5P546 R-GGA-8866546 https://reactome.org/PathwayBrowser/#/R-GGA-8866546 RNF5 and RNF185 ubiquitinate misfolded CFTR IEA Gallus gallus A0A1D5P546 R-GGA-8866553 https://reactome.org/PathwayBrowser/#/R-GGA-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Gallus gallus A0A1D5P546 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5P546 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5P546 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5P546 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5P546 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5P546 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5P546 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5P546 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5P546 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P546 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P546 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5P546 R-GGA-8869456 https://reactome.org/PathwayBrowser/#/R-GGA-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Gallus gallus A0A1D5P546 R-GGA-8869506 https://reactome.org/PathwayBrowser/#/R-GGA-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Gallus gallus A0A1D5P546 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5P546 R-GGA-8875183 https://reactome.org/PathwayBrowser/#/R-GGA-8875183 CBL monoubiquitinates activated MET IEA Gallus gallus A0A1D5P546 R-GGA-8875443 https://reactome.org/PathwayBrowser/#/R-GGA-8875443 USP8 deubiquitinates LRIG1 IEA Gallus gallus A0A1D5P546 R-GGA-8932355 https://reactome.org/PathwayBrowser/#/R-GGA-8932355 26S proteasome degrades Ub-NFE2L2 IEA Gallus gallus A0A1D5P546 R-GGA-8938770 https://reactome.org/PathwayBrowser/#/R-GGA-8938770 RNF144A binds PRKDC and Ubiquitin:UBE2L3 IEA Gallus gallus A0A1D5P546 R-GGA-8938773 https://reactome.org/PathwayBrowser/#/R-GGA-8938773 RNF144A polyubiquitinates PRKDC IEA Gallus gallus A0A1D5P546 R-GGA-8938815 https://reactome.org/PathwayBrowser/#/R-GGA-8938815 RNF152 polyubiquitinates RRAGA IEA Gallus gallus A0A1D5P546 R-GGA-8938829 https://reactome.org/PathwayBrowser/#/R-GGA-8938829 RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 IEA Gallus gallus A0A1D5P546 R-GGA-8939706 https://reactome.org/PathwayBrowser/#/R-GGA-8939706 SCF(SKP2) polyubiquitinates RUNX2 IEA Gallus gallus A0A1D5P546 R-GGA-8939801 https://reactome.org/PathwayBrowser/#/R-GGA-8939801 26S proteasome degrades PolyUb-RUNX2 IEA Gallus gallus A0A1D5P546 R-GGA-8943003 https://reactome.org/PathwayBrowser/#/R-GGA-8943003 SHPRH polyubiquitinates monoubiquitinated PCNA IEA Gallus gallus A0A1D5P546 R-GGA-8943007 https://reactome.org/PathwayBrowser/#/R-GGA-8943007 SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N IEA Gallus gallus A0A1D5P546 R-GGA-8948775 https://reactome.org/PathwayBrowser/#/R-GGA-8948775 MKRN1 polyubiquitinates PTEN IEA Gallus gallus A0A1D5P546 R-GGA-8948832 https://reactome.org/PathwayBrowser/#/R-GGA-8948832 RNF146 polyubiquitinates PARylated PTEN IEA Gallus gallus A0A1D5P546 R-GGA-8952382 https://reactome.org/PathwayBrowser/#/R-GGA-8952382 MDM2 polyubiquitinates RUNX3 IEA Gallus gallus A0A1D5P546 R-GGA-8952408 https://reactome.org/PathwayBrowser/#/R-GGA-8952408 Polyubiquitinated RUNX3 is degraded by the proteasome IEA Gallus gallus A0A1D5P546 R-GGA-8952419 https://reactome.org/PathwayBrowser/#/R-GGA-8952419 SMURFs ubiquitinate RUNX3 IEA Gallus gallus A0A1D5P546 R-GGA-8953917 https://reactome.org/PathwayBrowser/#/R-GGA-8953917 PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 IEA Gallus gallus A0A1D5P546 R-GGA-8953946 https://reactome.org/PathwayBrowser/#/R-GGA-8953946 PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 IEA Gallus gallus A0A1D5P546 R-GGA-8956106 https://reactome.org/PathwayBrowser/#/R-GGA-8956106 VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha IEA Gallus gallus A0A1D5P546 R-GGA-8956684 https://reactome.org/PathwayBrowser/#/R-GGA-8956684 ITCH polyubiquitinates TP73 IEA Gallus gallus A0A1D5P546 R-GGA-8957265 https://reactome.org/PathwayBrowser/#/R-GGA-8957265 26S proteasome degrades TP73 polyubiquitinated by ITCH IEA Gallus gallus A0A1D5P546 R-GGA-9009308 https://reactome.org/PathwayBrowser/#/R-GGA-9009308 STUB1 polyubiquitinates RUNX2 IEA Gallus gallus A0A1D5P546 R-GGA-9021523 https://reactome.org/PathwayBrowser/#/R-GGA-9021523 WWP2 ubiquitinates NOTCH3 IEA Gallus gallus A0A1D5P546 R-GGA-9033485 https://reactome.org/PathwayBrowser/#/R-GGA-9033485 PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 IEA Gallus gallus A0A1D5P546 R-GGA-9033491 https://reactome.org/PathwayBrowser/#/R-GGA-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Gallus gallus A0A1D5P546 R-GGA-9033499 https://reactome.org/PathwayBrowser/#/R-GGA-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Gallus gallus A0A1D5P546 R-GGA-9033509 https://reactome.org/PathwayBrowser/#/R-GGA-9033509 USP9X binds Ub:PEX5L IEA Gallus gallus A0A1D5P546 R-GGA-9033516 https://reactome.org/PathwayBrowser/#/R-GGA-9033516 PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Gallus gallus A0A1D5P546 R-GGA-9033527 https://reactome.org/PathwayBrowser/#/R-GGA-9033527 PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 IEA Gallus gallus A0A1D5P546 R-GGA-9033533 https://reactome.org/PathwayBrowser/#/R-GGA-9033533 PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Gallus gallus A0A1D5P546 R-GGA-909719 https://reactome.org/PathwayBrowser/#/R-GGA-909719 Recruitment of STAT2 to p-IFNAR1 IEA Gallus gallus A0A1D5P546 R-GGA-912627 https://reactome.org/PathwayBrowser/#/R-GGA-912627 CBL ubiquitinates PI3K IEA Gallus gallus A0A1D5P546 R-GGA-934604 https://reactome.org/PathwayBrowser/#/R-GGA-934604 Phosphorylated SPRY2 is ubiquitinated by CBL IEA Gallus gallus A0A1D5P546 R-GGA-936942 https://reactome.org/PathwayBrowser/#/R-GGA-936942 Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 IEA Gallus gallus A0A1D5P546 R-GGA-936947 https://reactome.org/PathwayBrowser/#/R-GGA-936947 Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex IEA Gallus gallus A0A1D5P546 R-GGA-936951 https://reactome.org/PathwayBrowser/#/R-GGA-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Gallus gallus A0A1D5P546 R-GGA-936952 https://reactome.org/PathwayBrowser/#/R-GGA-936952 Auto ubiquitination of TRAF6 bound to the activated TLR4 complex IEA Gallus gallus A0A1D5P546 R-GGA-936960 https://reactome.org/PathwayBrowser/#/R-GGA-936960 Activated TRAF6:p-IRAK2 interacts with TAK1 complex IEA Gallus gallus A0A1D5P546 R-GGA-936986 https://reactome.org/PathwayBrowser/#/R-GGA-936986 Activated TRAF6 synthesizes unanchored polyubiquitin chains IEA Gallus gallus A0A1D5P546 R-GGA-936991 https://reactome.org/PathwayBrowser/#/R-GGA-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Gallus gallus A0A1D5P546 R-GGA-937075 https://reactome.org/PathwayBrowser/#/R-GGA-937075 Phosphorylated TAK1 leaves activated TLR receptor complex IEA Gallus gallus A0A1D5P546 R-GGA-9641096 https://reactome.org/PathwayBrowser/#/R-GGA-9641096 Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub IEA Gallus gallus A0A1D5P546 R-GGA-9641111 https://reactome.org/PathwayBrowser/#/R-GGA-9641111 Parkin transfers Ub to misfolded proteins IEA Gallus gallus A0A1D5P546 R-GGA-9641127 https://reactome.org/PathwayBrowser/#/R-GGA-9641127 Ub:misfolded proteins polymerize to PolyUb:misfolded proteins IEA Gallus gallus A0A1D5P546 R-GGA-9645394 https://reactome.org/PathwayBrowser/#/R-GGA-9645394 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation IEA Gallus gallus A0A1D5P546 R-GGA-9645406 https://reactome.org/PathwayBrowser/#/R-GGA-9645406 ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) IEA Gallus gallus A0A1D5P546 R-GGA-9645414 https://reactome.org/PathwayBrowser/#/R-GGA-9645414 Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer IEA Gallus gallus A0A1D5P546 R-GGA-9645442 https://reactome.org/PathwayBrowser/#/R-GGA-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Gallus gallus A0A1D5P546 R-GGA-9646679 https://reactome.org/PathwayBrowser/#/R-GGA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Gallus gallus A0A1D5P546 R-GGA-9664888 https://reactome.org/PathwayBrowser/#/R-GGA-9664888 ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 IEA Gallus gallus A0A1D5P546 R-GGA-9674127 https://reactome.org/PathwayBrowser/#/R-GGA-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Gallus gallus A0A1D5P546 R-GGA-9684118 https://reactome.org/PathwayBrowser/#/R-GGA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5P546 R-GGA-9686969 https://reactome.org/PathwayBrowser/#/R-GGA-9686969 APC/C:Cdh1 polyubiquitinates SKP2 IEA Gallus gallus A0A1D5P546 R-GGA-9708517 https://reactome.org/PathwayBrowser/#/R-GGA-9708517 FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2)) IEA Gallus gallus A0A1D5P546 R-GGA-9750942 https://reactome.org/PathwayBrowser/#/R-GGA-9750942 USP14 deubiquitinates NLRC5 IEA Gallus gallus A0A1D5P546 R-GGA-9750946 https://reactome.org/PathwayBrowser/#/R-GGA-9750946 TRAF2,6 ubiquitinates NLRC5 IEA Gallus gallus A0A1D5P546 R-GGA-975097 https://reactome.org/PathwayBrowser/#/R-GGA-975097 Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation IEA Gallus gallus A0A1D5P546 R-GGA-975103 https://reactome.org/PathwayBrowser/#/R-GGA-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Gallus gallus A0A1D5P546 R-GGA-975147 https://reactome.org/PathwayBrowser/#/R-GGA-975147 Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane IEA Gallus gallus A0A1D5P546 R-GGA-9755303 https://reactome.org/PathwayBrowser/#/R-GGA-9755303 26S proteasome degrades HIFalpha IEA Gallus gallus A0A1D5P546 R-GGA-9755304 https://reactome.org/PathwayBrowser/#/R-GGA-9755304 MUL1 ubiquitinates UBXN7 IEA Gallus gallus A0A1D5P546 R-GGA-9755306 https://reactome.org/PathwayBrowser/#/R-GGA-9755306 ub UBXN7 is degraded by the 26S proteasome IEA Gallus gallus A0A1D5P546 R-GGA-9755505 https://reactome.org/PathwayBrowser/#/R-GGA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Gallus gallus A0A1D5P546 R-GGA-9759154 https://reactome.org/PathwayBrowser/#/R-GGA-9759154 TRIM21 ubiquitinates SQSTM1 IEA Gallus gallus A0A1D5P546 R-GGA-9759172 https://reactome.org/PathwayBrowser/#/R-GGA-9759172 KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer IEA Gallus gallus A0A1D5P546 R-GGA-9762091 https://reactome.org/PathwayBrowser/#/R-GGA-9762091 NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 IEA Gallus gallus A0A1D5P546 R-GGA-9762096 https://reactome.org/PathwayBrowser/#/R-GGA-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Gallus gallus A0A1D5P546 R-GGA-9766645 https://reactome.org/PathwayBrowser/#/R-GGA-9766645 CUL3:RBX1 ubiquitinates KEAP1 IEA Gallus gallus A0A1D5P546 R-GGA-9796342 https://reactome.org/PathwayBrowser/#/R-GGA-9796342 MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 IEA Gallus gallus A0A1D5P546 R-GGA-9796346 https://reactome.org/PathwayBrowser/#/R-GGA-9796346 MIB2 ubiquitinates RIPK1 at K377, K604, K634 IEA Gallus gallus A0A1D5P546 R-GGA-9796368 https://reactome.org/PathwayBrowser/#/R-GGA-9796368 RIPK1 binds STUB1 IEA Gallus gallus A0A1D5P546 R-GGA-9796387 https://reactome.org/PathwayBrowser/#/R-GGA-9796387 STUB1 ubiquitinates RIPK1 at K571, K604, K627 IEA Gallus gallus A0A1D5P546 R-GGA-9796617 https://reactome.org/PathwayBrowser/#/R-GGA-9796617 MIB2 binds CFLAR IEA Gallus gallus A0A1D5P546 R-GGA-9796626 https://reactome.org/PathwayBrowser/#/R-GGA-9796626 MIB2 ubiquitinates CFLAR IEA Gallus gallus A0A1D5P546 R-GGA-9815507 https://reactome.org/PathwayBrowser/#/R-GGA-9815507 MIB2 ubiquitinates CYLD at K338, K530 IEA Gallus gallus A0A1D5P546 R-GGA-9815510 https://reactome.org/PathwayBrowser/#/R-GGA-9815510 MIB2 binds CYLD IEA Gallus gallus A0A1D5P546 R-GGA-9823904 https://reactome.org/PathwayBrowser/#/R-GGA-9823904 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Gallus gallus A0A1D5P546 R-GGA-9823939 https://reactome.org/PathwayBrowser/#/R-GGA-9823939 IKKε (IKBKE) is ubiquitinated within the activated TLR4 IEA Gallus gallus A0A1D5P546 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5P546 R-GGA-983150 https://reactome.org/PathwayBrowser/#/R-GGA-983150 Proteasomal cleavage of substrate IEA Gallus gallus A0A1D5P546 R-GGA-983152 https://reactome.org/PathwayBrowser/#/R-GGA-983152 Transfer of ubiquitin from E1 to E2 IEA Gallus gallus A0A1D5P546 R-GGA-983153 https://reactome.org/PathwayBrowser/#/R-GGA-983153 E1 mediated ubiquitin activation IEA Gallus gallus A0A1D5P546 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5P546 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5P546 R-GGA-9861563 https://reactome.org/PathwayBrowser/#/R-GGA-9861563 CTLH E3 ligase ubiquitinates LDHA IEA Gallus gallus A0A1D5P546 R-GGA-9861640 https://reactome.org/PathwayBrowser/#/R-GGA-9861640 CTLH E3 ligase ubiquitinates PKM-1 IEA Gallus gallus A0A1D5P546 R-GGA-9934893 https://reactome.org/PathwayBrowser/#/R-GGA-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 IEA Gallus gallus A0A1D5P557 R-GGA-196857 https://reactome.org/PathwayBrowser/#/R-GGA-196857 PANK2 phosphorylates PanK IEA Gallus gallus A0A1D5P560 R-GGA-1236956 https://reactome.org/PathwayBrowser/#/R-GGA-1236956 Engulfment of particulate antigen into phagocytic vesicle IEA Gallus gallus A0A1D5P560 R-GGA-1236958 https://reactome.org/PathwayBrowser/#/R-GGA-1236958 Interaction of particulate antigens with dendritic cell receptors IEA Gallus gallus A0A1D5P560 R-GGA-216076 https://reactome.org/PathwayBrowser/#/R-GGA-216076 VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 IEA Gallus gallus A0A1D5P560 R-GGA-2395320 https://reactome.org/PathwayBrowser/#/R-GGA-2395320 Latent TGF-beta-1 binds integrins IEA Gallus gallus A0A1D5P560 R-GGA-2396029 https://reactome.org/PathwayBrowser/#/R-GGA-2396029 Latent TGF-beta-3 binds integrins IEA Gallus gallus A0A1D5P560 R-GGA-2426471 https://reactome.org/PathwayBrowser/#/R-GGA-2426471 VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 IEA Gallus gallus A0A1D5P560 R-GGA-2731074 https://reactome.org/PathwayBrowser/#/R-GGA-2731074 Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) IEA Gallus gallus A0A1D5P560 R-GGA-4085087 https://reactome.org/PathwayBrowser/#/R-GGA-4085087 Canstatin binds integrins alphaVbeta3, alphaVbeta5 IEA Gallus gallus A0A1D5P560 R-GGA-445699 https://reactome.org/PathwayBrowser/#/R-GGA-445699 ATP Hydrolysis By Myosin IEA Gallus gallus A0A1D5P560 R-GGA-445700 https://reactome.org/PathwayBrowser/#/R-GGA-445700 Myosin Binds ATP IEA Gallus gallus A0A1D5P560 R-GGA-445704 https://reactome.org/PathwayBrowser/#/R-GGA-445704 Calcium Binds Caldesmon IEA Gallus gallus A0A1D5P560 R-GGA-445705 https://reactome.org/PathwayBrowser/#/R-GGA-445705 Release Of ADP From Myosin IEA Gallus gallus A0A1D5P570 R-GGA-5695989 https://reactome.org/PathwayBrowser/#/R-GGA-5695989 ACAD11 dehydrogenates BH-CoA IEA Gallus gallus A0A1D5P573 R-GGA-212252 https://reactome.org/PathwayBrowser/#/R-GGA-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Gallus gallus A0A1D5P573 R-GGA-212263 https://reactome.org/PathwayBrowser/#/R-GGA-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Gallus gallus A0A1D5P592 R-GGA-2993447 https://reactome.org/PathwayBrowser/#/R-GGA-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Gallus gallus A0A1D5P592 R-GGA-3323111 https://reactome.org/PathwayBrowser/#/R-GGA-3323111 Cytoslic carboxylases translocate to mitochondrial matrix IEA Gallus gallus A0A1D5P592 R-GGA-71031 https://reactome.org/PathwayBrowser/#/R-GGA-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Gallus gallus A0A1D5P592 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1D5P592 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1D5P599 R-GGA-430311 https://reactome.org/PathwayBrowser/#/R-GGA-430311 Rsu-1 interacts with Pinch1 IEA Gallus gallus A0A1D5P5B2 R-GGA-70745 https://reactome.org/PathwayBrowser/#/R-GGA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Gallus gallus A0A1D5P5B6 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5P5B6 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5P5B6 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus A0A1D5P5B7 R-GGA-8850961 https://reactome.org/PathwayBrowser/#/R-GGA-8850961 PREX2 binds PTEN and inhibits it IEA Gallus gallus A0A1D5P5B7 R-GGA-8980691 https://reactome.org/PathwayBrowser/#/R-GGA-8980691 RHOA GEFs activate RHOA IEA Gallus gallus A0A1D5P5B7 R-GGA-9013143 https://reactome.org/PathwayBrowser/#/R-GGA-9013143 RAC1 GEFs activate RAC1 IEA Gallus gallus A0A1D5P5B7 R-GGA-9013159 https://reactome.org/PathwayBrowser/#/R-GGA-9013159 CDC42 GEFs activate CDC42 IEA Gallus gallus A0A1D5P5B8 R-GGA-416639 https://reactome.org/PathwayBrowser/#/R-GGA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Gallus gallus A0A1D5P5B8 R-GGA-416985 https://reactome.org/PathwayBrowser/#/R-GGA-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Gallus gallus A0A1D5P5B8 R-GGA-421007 https://reactome.org/PathwayBrowser/#/R-GGA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5P5C1 R-GGA-202703 https://reactome.org/PathwayBrowser/#/R-GGA-202703 CD47 binds SIRP IEA Gallus gallus A0A1D5P5C1 R-GGA-391151 https://reactome.org/PathwayBrowser/#/R-GGA-391151 p-4Y-SIRPA:CD47:SKAP2 binds FYB IEA Gallus gallus A0A1D5P5C1 R-GGA-391152 https://reactome.org/PathwayBrowser/#/R-GGA-391152 p-4Y-SIRPA:CD47 binds PTK2B IEA Gallus gallus A0A1D5P5C1 R-GGA-391153 https://reactome.org/PathwayBrowser/#/R-GGA-391153 p-4Y-SIRPA:CD47 binds GRB2-1 IEA Gallus gallus A0A1D5P5C1 R-GGA-391155 https://reactome.org/PathwayBrowser/#/R-GGA-391155 SIRPA binds SFTPA oligomer, SFTPD oligomer IEA Gallus gallus A0A1D5P5C1 R-GGA-391157 https://reactome.org/PathwayBrowser/#/R-GGA-391157 p-4Y-SIRPA:CD47 binds SKAP2 IEA Gallus gallus A0A1D5P5C1 R-GGA-391158 https://reactome.org/PathwayBrowser/#/R-GGA-391158 SIRP alpha binds CD47 IEA Gallus gallus A0A1D5P5C1 R-GGA-391168 https://reactome.org/PathwayBrowser/#/R-GGA-391168 SIRP gamma binds CD47 IEA Gallus gallus A0A1D5P5C1 R-GGA-6798747 https://reactome.org/PathwayBrowser/#/R-GGA-6798747 Exocytosis of tertiary granule membrane proteins IEA Gallus gallus A0A1D5P5C1 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1D5P5C3 R-GGA-3299569 https://reactome.org/PathwayBrowser/#/R-GGA-3299569 Beta-catenin displaces TLE:HDAC1 from TCF/LEF IEA Gallus gallus A0A1D5P5C3 R-GGA-3322429 https://reactome.org/PathwayBrowser/#/R-GGA-3322429 XIAP monoubiquinates TLE IEA Gallus gallus A0A1D5P5C3 R-GGA-3322431 https://reactome.org/PathwayBrowser/#/R-GGA-3322431 XIAP binds TLE IEA Gallus gallus A0A1D5P5C3 R-GGA-3322434 https://reactome.org/PathwayBrowser/#/R-GGA-3322434 XIAP dissociates from ub-TLE IEA Gallus gallus A0A1D5P5C3 R-GGA-3361751 https://reactome.org/PathwayBrowser/#/R-GGA-3361751 beta-catenin is replaced by repression complexes at the promoter IEA Gallus gallus A0A1D5P5C3 R-GGA-4641229 https://reactome.org/PathwayBrowser/#/R-GGA-4641229 TLE oligomerizes IEA Gallus gallus A0A1D5P5C3 R-GGA-8944349 https://reactome.org/PathwayBrowser/#/R-GGA-8944349 TLE tetramers bind TCF/LEF at WNT promoters IEA Gallus gallus A0A1D5P5C7 R-GGA-1676162 https://reactome.org/PathwayBrowser/#/R-GGA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Gallus gallus A0A1D5P5C7 R-GGA-1676164 https://reactome.org/PathwayBrowser/#/R-GGA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Gallus gallus A0A1D5P5C7 R-GGA-1855180 https://reactome.org/PathwayBrowser/#/R-GGA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Gallus gallus A0A1D5P5C7 R-GGA-1855202 https://reactome.org/PathwayBrowser/#/R-GGA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Gallus gallus A0A1D5P5C9 R-GGA-210404 https://reactome.org/PathwayBrowser/#/R-GGA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Gallus gallus A0A1D5P5C9 R-GGA-428015 https://reactome.org/PathwayBrowser/#/R-GGA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Gallus gallus A0A1D5P5D8 R-GGA-9817575 https://reactome.org/PathwayBrowser/#/R-GGA-9817575 ERO1B oxidizes P4HB IEA Gallus gallus A0A1D5P5F4 R-GGA-1475022 https://reactome.org/PathwayBrowser/#/R-GGA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Gallus gallus A0A1D5P5F4 R-GGA-1475026 https://reactome.org/PathwayBrowser/#/R-GGA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Gallus gallus A0A1D5P5G1 R-GGA-6803523 https://reactome.org/PathwayBrowser/#/R-GGA-6803523 PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA IEA Gallus gallus A0A1D5P5G1 R-GGA-72103 https://reactome.org/PathwayBrowser/#/R-GGA-72103 Formation of pre-mRNPs IEA Gallus gallus A0A1D5P5G1 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5P5H3 R-GGA-374298 https://reactome.org/PathwayBrowser/#/R-GGA-374298 Opioid receptors bind opioid peptides IEA Gallus gallus A0A1D5P5H3 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5P5H3 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5P5H3 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5P5H5 R-GGA-5689544 https://reactome.org/PathwayBrowser/#/R-GGA-5689544 UCHL5 binds INO80 complex IEA Gallus gallus A0A1D5P5H5 R-GGA-5691006 https://reactome.org/PathwayBrowser/#/R-GGA-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Gallus gallus A0A1D5P5I5 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5P5I7 R-GGA-376419 https://reactome.org/PathwayBrowser/#/R-GGA-376419 Formation of NR-MED1 Coactivator Complex IEA Gallus gallus A0A1D5P5I7 R-GGA-382096 https://reactome.org/PathwayBrowser/#/R-GGA-382096 Formation of NR-NCOR Corepressor Complex IEA Gallus gallus A0A1D5P5J3 R-GGA-375140 https://reactome.org/PathwayBrowser/#/R-GGA-375140 CDO binds promyogenic cadherins IEA Gallus gallus A0A1D5P5J3 R-GGA-419001 https://reactome.org/PathwayBrowser/#/R-GGA-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Gallus gallus A0A1D5P5J3 R-GGA-419002 https://reactome.org/PathwayBrowser/#/R-GGA-419002 Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin IEA Gallus gallus A0A1D5P5J3 R-GGA-448958 https://reactome.org/PathwayBrowser/#/R-GGA-448958 Nuclear translocation of p38 MAPK IEA Gallus gallus A0A1D5P5L2 R-GGA-140664 https://reactome.org/PathwayBrowser/#/R-GGA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Gallus gallus A0A1D5P5L2 R-GGA-140686 https://reactome.org/PathwayBrowser/#/R-GGA-140686 factor Va + factor Xa -> Va:Xa complex (prothrombinase) IEA Gallus gallus A0A1D5P5L2 R-GGA-140696 https://reactome.org/PathwayBrowser/#/R-GGA-140696 factor V -> factor Va + factor V activation peptide (thrombin catalyst) IEA Gallus gallus A0A1D5P5L2 R-GGA-141026 https://reactome.org/PathwayBrowser/#/R-GGA-141026 Activated protein C cleaves factor Va to factor Vi intermediate form IEA Gallus gallus A0A1D5P5L2 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus A0A1D5P5L2 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus A0A1D5P5L2 R-GGA-481007 https://reactome.org/PathwayBrowser/#/R-GGA-481007 Exocytosis of platelet alpha granule contents IEA Gallus gallus A0A1D5P5L2 R-GGA-5591040 https://reactome.org/PathwayBrowser/#/R-GGA-5591040 Activated protein C cleaves Factor Va intermediate form for Factor Va IEA Gallus gallus A0A1D5P5L2 R-GGA-5607002 https://reactome.org/PathwayBrowser/#/R-GGA-5607002 Activated protein C cleaves factor VIIIa IEA Gallus gallus A0A1D5P5L2 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus A0A1D5P5L2 R-GGA-5694417 https://reactome.org/PathwayBrowser/#/R-GGA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Gallus gallus A0A1D5P5L2 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus A0A1D5P5L2 R-GGA-5694431 https://reactome.org/PathwayBrowser/#/R-GGA-5694431 Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors IEA Gallus gallus A0A1D5P5L2 R-GGA-5694446 https://reactome.org/PathwayBrowser/#/R-GGA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Gallus gallus A0A1D5P5L2 R-GGA-5694522 https://reactome.org/PathwayBrowser/#/R-GGA-5694522 Inner coat assembly and cargo binding IEA Gallus gallus A0A1D5P5L2 R-GGA-5694527 https://reactome.org/PathwayBrowser/#/R-GGA-5694527 Loss of SAR1B GTPase IEA Gallus gallus A0A1D5P5L2 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5P5L2 R-GGA-9015122 https://reactome.org/PathwayBrowser/#/R-GGA-9015122 Factor Xa inhibitors bind Va:Xa IEA Gallus gallus A0A1D5P5L4 R-GGA-8875318 https://reactome.org/PathwayBrowser/#/R-GGA-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Gallus gallus A0A1D5P5L4 R-GGA-8877308 https://reactome.org/PathwayBrowser/#/R-GGA-8877308 MADD exchanges GTP for GDP on RAB27 IEA Gallus gallus A0A1D5P5L8 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus A0A1D5P5L8 R-GGA-6799178 https://reactome.org/PathwayBrowser/#/R-GGA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Gallus gallus A0A1D5P5L8 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus A0A1D5P5L8 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus A0A1D5P5L8 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus A0A1D5P5L8 R-GGA-6799202 https://reactome.org/PathwayBrowser/#/R-GGA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Gallus gallus A0A1D5P5L8 R-GGA-6799203 https://reactome.org/PathwayBrowser/#/R-GGA-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Gallus gallus A0A1D5P5L8 R-GGA-6800868 https://reactome.org/PathwayBrowser/#/R-GGA-6800868 NDUF subunits bind to form the IP subcomplex IEA Gallus gallus A0A1D5P5Q9 R-GGA-446200 https://reactome.org/PathwayBrowser/#/R-GGA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Gallus gallus A0A1D5P5R9 R-GGA-1222516 https://reactome.org/PathwayBrowser/#/R-GGA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Gallus gallus A0A1D5P5R9 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5P5R9 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1D5P5R9 R-GGA-74723 https://reactome.org/PathwayBrowser/#/R-GGA-74723 Endosome acidification IEA Gallus gallus A0A1D5P5R9 R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus A0A1D5P5S2 R-GGA-5675373 https://reactome.org/PathwayBrowser/#/R-GGA-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Gallus gallus A0A1D5P5S7 R-GGA-430021 https://reactome.org/PathwayBrowser/#/R-GGA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Gallus gallus A0A1D5P5S8 R-GGA-5653838 https://reactome.org/PathwayBrowser/#/R-GGA-5653838 POLD,POLE binds deISGylated PCNA after TLS IEA Gallus gallus A0A1D5P5S8 R-GGA-5655193 https://reactome.org/PathwayBrowser/#/R-GGA-5655193 KIAA0101 double monoubiquitination IEA Gallus gallus A0A1D5P5T1 R-GGA-156808 https://reactome.org/PathwayBrowser/#/R-GGA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Gallus gallus A0A1D5P5T1 R-GGA-157849 https://reactome.org/PathwayBrowser/#/R-GGA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Gallus gallus A0A1D5P5T1 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus A0A1D5P5T1 R-GGA-72676 https://reactome.org/PathwayBrowser/#/R-GGA-72676 eIF3 and eIF1A bind to the 40S subunit IEA Gallus gallus A0A1D5P5T1 R-GGA-72691 https://reactome.org/PathwayBrowser/#/R-GGA-72691 Formation of the 43S pre-initiation complex IEA Gallus gallus A0A1D5P5T1 R-GGA-72697 https://reactome.org/PathwayBrowser/#/R-GGA-72697 Start codon recognition IEA Gallus gallus A0A1D5P5T8 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus A0A1D5P5T8 R-GGA-77591 https://reactome.org/PathwayBrowser/#/R-GGA-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Gallus gallus A0A1D5P5T8 R-GGA-77592 https://reactome.org/PathwayBrowser/#/R-GGA-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Gallus gallus A0A1D5P5T8 R-GGA-77593 https://reactome.org/PathwayBrowser/#/R-GGA-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Gallus gallus A0A1D5P5V5 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus A0A1D5P5V5 R-GGA-166795 https://reactome.org/PathwayBrowser/#/R-GGA-166795 Formation of Classical C3 convertase (C4b:C2a complex) IEA Gallus gallus A0A1D5P5V5 R-GGA-166817 https://reactome.org/PathwayBrowser/#/R-GGA-166817 Cleavage of C3 by C3 convertases IEA Gallus gallus A0A1D5P5V5 R-GGA-173636 https://reactome.org/PathwayBrowser/#/R-GGA-173636 Formation of classic pathway C5 convertase IEA Gallus gallus A0A1D5P5V5 R-GGA-173680 https://reactome.org/PathwayBrowser/#/R-GGA-173680 Activation of C5 IEA Gallus gallus A0A1D5P5V5 R-GGA-2855047 https://reactome.org/PathwayBrowser/#/R-GGA-2855047 Hydrolysis of internal thioester in C4b IEA Gallus gallus A0A1D5P5V5 R-GGA-8951486 https://reactome.org/PathwayBrowser/#/R-GGA-8951486 CD46 binds C4b IEA Gallus gallus A0A1D5P5V5 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5P5V5 R-GGA-977375 https://reactome.org/PathwayBrowser/#/R-GGA-977375 CR1 binds C3bBb/C4bC2a IEA Gallus gallus A0A1D5P5V5 R-GGA-977602 https://reactome.org/PathwayBrowser/#/R-GGA-977602 Complement factor I binds to MCP, CR1:C4b, C3b IEA Gallus gallus A0A1D5P5V5 R-GGA-977615 https://reactome.org/PathwayBrowser/#/R-GGA-977615 Factor I inactivates MCP/CR1-bound C4b/C3b IEA Gallus gallus A0A1D5P5V5 R-GGA-977619 https://reactome.org/PathwayBrowser/#/R-GGA-977619 CD55 (DAF) promotes C3bBb/C4bC2a dissociation IEA Gallus gallus A0A1D5P5V5 R-GGA-977629 https://reactome.org/PathwayBrowser/#/R-GGA-977629 Displacement of C2a/Bb by CR1 IEA Gallus gallus A0A1D5P5V5 R-GGA-981535 https://reactome.org/PathwayBrowser/#/R-GGA-981535 CD55 (DAF) binds C3bBb, C4bC2a IEA Gallus gallus A0A1D5P5V5 R-GGA-981713 https://reactome.org/PathwayBrowser/#/R-GGA-981713 C4b binds to cell surface IEA Gallus gallus A0A1D5P5V8 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5P5X4 R-GGA-442368 https://reactome.org/PathwayBrowser/#/R-GGA-442368 SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Gallus gallus A0A1D5P5X4 R-GGA-917933 https://reactome.org/PathwayBrowser/#/R-GGA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Gallus gallus A0A1D5P5X8 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5P5X8 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5P5X8 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5P5X8 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5P5X8 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5P5Z0 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5P5Z0 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5P5Z0 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5P5Z0 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5P5Z0 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5P5Z0 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus A0A1D5P5Z0 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1D5P5Z0 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5P5Z0 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5P5Z0 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5P5Z0 R-GGA-8849350 https://reactome.org/PathwayBrowser/#/R-GGA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Gallus gallus A0A1D5P5Z0 R-GGA-8849353 https://reactome.org/PathwayBrowser/#/R-GGA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Gallus gallus A0A1D5P5Z0 R-GGA-9646679 https://reactome.org/PathwayBrowser/#/R-GGA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Gallus gallus A0A1D5P5Z0 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1D5P5Z0 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus A0A1D5P622 R-GGA-373073 https://reactome.org/PathwayBrowser/#/R-GGA-373073 Receptors CCR1, 2 and 8 bind CCL16 ligand IEA Gallus gallus A0A1D5P622 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5P622 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5P622 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5P622 R-GGA-8851352 https://reactome.org/PathwayBrowser/#/R-GGA-8851352 CCR8 binds CCL1 IEA Gallus gallus A0A1D5P632 R-GGA-77608 https://reactome.org/PathwayBrowser/#/R-GGA-77608 Binding of A1CF to stem-looped RNA IEA Gallus gallus A0A1D5P635 R-GGA-5685318 https://reactome.org/PathwayBrowser/#/R-GGA-5685318 BCDX2 complex formation IEA Gallus gallus A0A1D5P635 R-GGA-5685319 https://reactome.org/PathwayBrowser/#/R-GGA-5685319 CX3 complex formation IEA Gallus gallus A0A1D5P635 R-GGA-5685341 https://reactome.org/PathwayBrowser/#/R-GGA-5685341 BCDX2 complex stabilizes RAD51 filament IEA Gallus gallus A0A1D5P635 R-GGA-5685838 https://reactome.org/PathwayBrowser/#/R-GGA-5685838 CX3 complex binds D-loop structures IEA Gallus gallus A0A1D5P635 R-GGA-5693539 https://reactome.org/PathwayBrowser/#/R-GGA-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Gallus gallus A0A1D5P635 R-GGA-5693584 https://reactome.org/PathwayBrowser/#/R-GGA-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Gallus gallus A0A1D5P635 R-GGA-5693593 https://reactome.org/PathwayBrowser/#/R-GGA-5693593 D-loop extension by DNA polymerases IEA Gallus gallus A0A1D5P635 R-GGA-5693620 https://reactome.org/PathwayBrowser/#/R-GGA-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Gallus gallus A0A1D5P635 R-GGA-983218 https://reactome.org/PathwayBrowser/#/R-GGA-983218 RAD51B:RAD51C binds single-stranded DNA IEA Gallus gallus A0A1D5P635 R-GGA-983285 https://reactome.org/PathwayBrowser/#/R-GGA-983285 RAD51B binds RAD51C IEA Gallus gallus A0A1D5P635 R-GGA-9853389 https://reactome.org/PathwayBrowser/#/R-GGA-9853389 FIGNL1 binds RAD51 IEA Gallus gallus A0A1D5P640 R-GGA-418442 https://reactome.org/PathwayBrowser/#/R-GGA-418442 PKG1 phosphorylates IRAG:IP3R1 inhibiting IP3-stimulated Ca2+ release IEA Gallus gallus A0A1D5P642 R-GGA-1236943 https://reactome.org/PathwayBrowser/#/R-GGA-1236943 Loading of antigen peptide onto MHC class I molecule IEA Gallus gallus A0A1D5P642 R-GGA-1236954 https://reactome.org/PathwayBrowser/#/R-GGA-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Gallus gallus A0A1D5P642 R-GGA-1236964 https://reactome.org/PathwayBrowser/#/R-GGA-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Gallus gallus A0A1D5P642 R-GGA-1236965 https://reactome.org/PathwayBrowser/#/R-GGA-1236965 Export of peptide loaded MHC class I complex to PM IEA Gallus gallus A0A1D5P642 R-GGA-198955 https://reactome.org/PathwayBrowser/#/R-GGA-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Gallus gallus A0A1D5P642 R-GGA-199062 https://reactome.org/PathwayBrowser/#/R-GGA-199062 KLRC1:KLRD1 heterodimer interacts with HLA-E IEA Gallus gallus A0A1D5P642 R-GGA-210289 https://reactome.org/PathwayBrowser/#/R-GGA-210289 Recruitment of SYK to p-DAP12 IEA Gallus gallus A0A1D5P642 R-GGA-2395412 https://reactome.org/PathwayBrowser/#/R-GGA-2395412 Phosphorylation of SYK IEA Gallus gallus A0A1D5P642 R-GGA-2396594 https://reactome.org/PathwayBrowser/#/R-GGA-2396594 Phosphorylation of SLP-76 by p-SYK IEA Gallus gallus A0A1D5P642 R-GGA-2424480 https://reactome.org/PathwayBrowser/#/R-GGA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5P642 R-GGA-2424482 https://reactome.org/PathwayBrowser/#/R-GGA-2424482 p85 regulatory unit of PI3K binds p-6Y-SYK IEA Gallus gallus A0A1D5P642 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus A0A1D5P642 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus A0A1D5P642 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus A0A1D5P642 R-GGA-5691154 https://reactome.org/PathwayBrowser/#/R-GGA-5691154 HFE binds TFRC dimer IEA Gallus gallus A0A1D5P642 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5P642 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5P642 R-GGA-8863973 https://reactome.org/PathwayBrowser/#/R-GGA-8863973 Fusion of ERC and phagosome IEA Gallus gallus A0A1D5P642 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus A0A1D5P642 R-GGA-8951499 https://reactome.org/PathwayBrowser/#/R-GGA-8951499 Loading of antigenic peptides on to class I MHC IEA Gallus gallus A0A1D5P642 R-GGA-983138 https://reactome.org/PathwayBrowser/#/R-GGA-983138 Transport of MHC heterotrimer to ER exit site IEA Gallus gallus A0A1D5P642 R-GGA-983145 https://reactome.org/PathwayBrowser/#/R-GGA-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Gallus gallus A0A1D5P642 R-GGA-983146 https://reactome.org/PathwayBrowser/#/R-GGA-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Gallus gallus A0A1D5P642 R-GGA-983421 https://reactome.org/PathwayBrowser/#/R-GGA-983421 Journey of cargo through Golgi complex IEA Gallus gallus A0A1D5P642 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus A0A1D5P642 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus A0A1D5P642 R-GGA-983425 https://reactome.org/PathwayBrowser/#/R-GGA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Gallus gallus A0A1D5P642 R-GGA-983427 https://reactome.org/PathwayBrowser/#/R-GGA-983427 Expression of peptide bound class I MHC on cell surface IEA Gallus gallus A0A1D5P643 R-GGA-5688797 https://reactome.org/PathwayBrowser/#/R-GGA-5688797 ATXN3 family cleave Ub chains IEA Gallus gallus A0A1D5P648 R-GGA-2454081 https://reactome.org/PathwayBrowser/#/R-GGA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Gallus gallus A0A1D5P648 R-GGA-5362518 https://reactome.org/PathwayBrowser/#/R-GGA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Gallus gallus A0A1D5P650 R-GGA-190519 https://reactome.org/PathwayBrowser/#/R-GGA-190519 Internalization of gap junction plaques IEA Gallus gallus A0A1D5P650 R-GGA-190829 https://reactome.org/PathwayBrowser/#/R-GGA-190829 Lysosomal degradation of gap junction plaques IEA Gallus gallus A0A1D5P650 R-GGA-196017 https://reactome.org/PathwayBrowser/#/R-GGA-196017 Dynamin is recruited to the gap junction plaque IEA Gallus gallus A0A1D5P650 R-GGA-196026 https://reactome.org/PathwayBrowser/#/R-GGA-196026 Dab2 is recruited to the junctional plaques IEA Gallus gallus A0A1D5P650 R-GGA-3928654 https://reactome.org/PathwayBrowser/#/R-GGA-3928654 Clathrin internalises EPH:EFN complexes IEA Gallus gallus A0A1D5P650 R-GGA-8856813 https://reactome.org/PathwayBrowser/#/R-GGA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Gallus gallus A0A1D5P650 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5P650 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5P650 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5P650 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5P650 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5P650 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5P650 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5P650 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5P650 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P650 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P650 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5P650 R-GGA-8871196 https://reactome.org/PathwayBrowser/#/R-GGA-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Gallus gallus A0A1D5P653 R-GGA-1296127 https://reactome.org/PathwayBrowser/#/R-GGA-1296127 Activation of voltage gated Potassium channels IEA Gallus gallus A0A1D5P665 R-GGA-5336466 https://reactome.org/PathwayBrowser/#/R-GGA-5336466 MRS2 transports Mg2+ from cytosol to mitochondrial matrix IEA Gallus gallus A0A1D5P669 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5P669 R-GGA-9014294 https://reactome.org/PathwayBrowser/#/R-GGA-9014294 RAC2 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5P669 R-GGA-9014449 https://reactome.org/PathwayBrowser/#/R-GGA-9014449 RHOG binds effectors at the plasma membrane IEA Gallus gallus A0A1D5P669 R-GGA-9018746 https://reactome.org/PathwayBrowser/#/R-GGA-9018746 RHOQ binds effectors at the plasma membrane IEA Gallus gallus A0A1D5P669 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5P6A0 R-GGA-418553 https://reactome.org/PathwayBrowser/#/R-GGA-418553 cAMP degradation by Phosphodiesterases IEA Gallus gallus A0A1D5P6A4 R-GGA-1676048 https://reactome.org/PathwayBrowser/#/R-GGA-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Gallus gallus A0A1D5P6A4 R-GGA-1676109 https://reactome.org/PathwayBrowser/#/R-GGA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Gallus gallus A0A1D5P6A4 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5P6A4 R-GGA-388830 https://reactome.org/PathwayBrowser/#/R-GGA-388830 PI3K binds ICOS IEA Gallus gallus A0A1D5P6A4 R-GGA-388832 https://reactome.org/PathwayBrowser/#/R-GGA-388832 PI3K binds CD28 IEA Gallus gallus A0A1D5P6A4 R-GGA-389158 https://reactome.org/PathwayBrowser/#/R-GGA-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5P6A4 R-GGA-392295 https://reactome.org/PathwayBrowser/#/R-GGA-392295 Gbeta:gamma recruits PI3K gamma IEA Gallus gallus A0A1D5P6A4 R-GGA-392300 https://reactome.org/PathwayBrowser/#/R-GGA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Gallus gallus A0A1D5P6A4 R-GGA-437162 https://reactome.org/PathwayBrowser/#/R-GGA-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Gallus gallus A0A1D5P6B3 R-GGA-76056 https://reactome.org/PathwayBrowser/#/R-GGA-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Gallus gallus A0A1D5P6B3 R-GGA-83805 https://reactome.org/PathwayBrowser/#/R-GGA-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Gallus gallus A0A1D5P6C6 R-GGA-9913339 https://reactome.org/PathwayBrowser/#/R-GGA-9913339 Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC IEA Gallus gallus A0A1D5P6D2 R-GGA-5691006 https://reactome.org/PathwayBrowser/#/R-GGA-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Gallus gallus A0A1D5P6D2 R-GGA-6781833 https://reactome.org/PathwayBrowser/#/R-GGA-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Gallus gallus A0A1D5P6D2 R-GGA-8863721 https://reactome.org/PathwayBrowser/#/R-GGA-8863721 NEDD8-STON binds TOR1 hexamer and COP9 complex IEA Gallus gallus A0A1D5P6D2 R-GGA-8863723 https://reactome.org/PathwayBrowser/#/R-GGA-8863723 COP9 and TOR1 deneddylate STON2 IEA Gallus gallus A0A1D5P6D2 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5P6D2 R-GGA-8956045 https://reactome.org/PathwayBrowser/#/R-GGA-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P6D5 R-GGA-426240 https://reactome.org/PathwayBrowser/#/R-GGA-426240 DAG kinase produces phosphatidic acid from DAG IEA Gallus gallus A0A1D5P6E0 R-GGA-202714 https://reactome.org/PathwayBrowser/#/R-GGA-202714 CD58 binds CD2 IEA Gallus gallus A0A1D5P6E0 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5P6E0 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1D5P6E9 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5P6F6 R-GGA-2744361 https://reactome.org/PathwayBrowser/#/R-GGA-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Gallus gallus A0A1D5P6F6 R-GGA-2752067 https://reactome.org/PathwayBrowser/#/R-GGA-2752067 BESTs transport cytosolic HCO3- to extracellular region IEA Gallus gallus A0A1D5P6G7 R-GGA-429860 https://reactome.org/PathwayBrowser/#/R-GGA-429860 DCP1-DCP2 complex decaps mRNA IEA Gallus gallus A0A1D5P6G7 R-GGA-450488 https://reactome.org/PathwayBrowser/#/R-GGA-450488 BRF1 Complex recruits RNA degradation activities IEA Gallus gallus A0A1D5P6H2 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5P6H2 R-GGA-6811433 https://reactome.org/PathwayBrowser/#/R-GGA-6811433 The COG tethering complex interacts with numerous SNAREs at the Golgi membrane IEA Gallus gallus A0A1D5P6H9 R-GGA-1981120 https://reactome.org/PathwayBrowser/#/R-GGA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Gallus gallus A0A1D5P6H9 R-GGA-8948228 https://reactome.org/PathwayBrowser/#/R-GGA-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Gallus gallus A0A1D5P6H9 R-GGA-8948231 https://reactome.org/PathwayBrowser/#/R-GGA-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Gallus gallus A0A1D5P6I1 R-GGA-2059926 https://reactome.org/PathwayBrowser/#/R-GGA-2059926 NPHP4 protein binds LATS proteins IEA Gallus gallus A0A1D5P6I1 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5P6I1 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1D5P6I1 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1D5P6J0 R-GGA-70800 https://reactome.org/PathwayBrowser/#/R-GGA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Gallus gallus A0A1D5P6J0 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1D5P6J0 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1D5P6K3 R-GGA-2404137 https://reactome.org/PathwayBrowser/#/R-GGA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus A0A1D5P6K3 R-GGA-2404142 https://reactome.org/PathwayBrowser/#/R-GGA-2404142 atROL binds RBP1 IEA Gallus gallus A0A1D5P6K3 R-GGA-2404144 https://reactome.org/PathwayBrowser/#/R-GGA-2404144 Parenchymal atROL translocates to HSCs IEA Gallus gallus A0A1D5P6K3 R-GGA-2453855 https://reactome.org/PathwayBrowser/#/R-GGA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus A0A1D5P6K3 R-GGA-2855259 https://reactome.org/PathwayBrowser/#/R-GGA-2855259 atROL binds RBP1 (parenchymal cell) IEA Gallus gallus A0A1D5P6K3 R-GGA-74843 https://reactome.org/PathwayBrowser/#/R-GGA-74843 atROL binds RBP1 to form RBP1:atROL IEA Gallus gallus A0A1D5P6L6 R-GGA-1222516 https://reactome.org/PathwayBrowser/#/R-GGA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Gallus gallus A0A1D5P6L6 R-GGA-74723 https://reactome.org/PathwayBrowser/#/R-GGA-74723 Endosome acidification IEA Gallus gallus A0A1D5P6L6 R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus A0A1D5P6L6 R-GGA-9639286 https://reactome.org/PathwayBrowser/#/R-GGA-9639286 RRAGC,D exchanges GTP for GDP IEA Gallus gallus A0A1D5P6L6 R-GGA-9640167 https://reactome.org/PathwayBrowser/#/R-GGA-9640167 RRAGA,B exchanges GDP for GTP IEA Gallus gallus A0A1D5P6L6 R-GGA-9640168 https://reactome.org/PathwayBrowser/#/R-GGA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Gallus gallus A0A1D5P6L6 R-GGA-9640175 https://reactome.org/PathwayBrowser/#/R-GGA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Gallus gallus A0A1D5P6L6 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus A0A1D5P6L6 R-GGA-9645598 https://reactome.org/PathwayBrowser/#/R-GGA-9645598 RRAGC,D hydrolyzes GTP IEA Gallus gallus A0A1D5P6L6 R-GGA-9645608 https://reactome.org/PathwayBrowser/#/R-GGA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Gallus gallus A0A1D5P6L6 R-GGA-9646468 https://reactome.org/PathwayBrowser/#/R-GGA-9646468 mTORC1 binds RHEB:GTP IEA Gallus gallus A0A1D5P6L7 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5P6L7 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5P6L7 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5P6L7 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5P6M5 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus A0A1D5P6M8 R-GGA-6798745 https://reactome.org/PathwayBrowser/#/R-GGA-6798745 Exocytosis of tertiary granule lumen proteins IEA Gallus gallus A0A1D5P6M8 R-GGA-6798749 https://reactome.org/PathwayBrowser/#/R-GGA-6798749 Exocytosis of specific granule lumen proteins IEA Gallus gallus A0A1D5P6N1 R-GGA-6791222 https://reactome.org/PathwayBrowser/#/R-GGA-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Gallus gallus A0A1D5P6N1 R-GGA-6791227 https://reactome.org/PathwayBrowser/#/R-GGA-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Gallus gallus A0A1D5P6N3 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5P6N9 R-GGA-76056 https://reactome.org/PathwayBrowser/#/R-GGA-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Gallus gallus A0A1D5P6N9 R-GGA-83803 https://reactome.org/PathwayBrowser/#/R-GGA-83803 Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex IEA Gallus gallus A0A1D5P6N9 R-GGA-83805 https://reactome.org/PathwayBrowser/#/R-GGA-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Gallus gallus A0A1D5P6P5 R-GGA-3295579 https://reactome.org/PathwayBrowser/#/R-GGA-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Gallus gallus A0A1D5P6Q5 R-GGA-163756 https://reactome.org/PathwayBrowser/#/R-GGA-163756 Formation of fatty acid synthase (FAS) dimer IEA Gallus gallus A0A1D5P6Q5 R-GGA-199202 https://reactome.org/PathwayBrowser/#/R-GGA-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Gallus gallus A0A1D5P6Q5 R-GGA-75872 https://reactome.org/PathwayBrowser/#/R-GGA-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Gallus gallus A0A1D5P6Q6 R-GGA-2106614 https://reactome.org/PathwayBrowser/#/R-GGA-2106614 Duplex miRNA is loaded into Argonaute IEA Gallus gallus A0A1D5P6Q6 R-GGA-2106615 https://reactome.org/PathwayBrowser/#/R-GGA-2106615 Removal of siRNA passenger strand IEA Gallus gallus A0A1D5P6Q6 R-GGA-2106625 https://reactome.org/PathwayBrowser/#/R-GGA-2106625 Duplex siRNA is loaded into Argonaute IEA Gallus gallus A0A1D5P6Q6 R-GGA-210805 https://reactome.org/PathwayBrowser/#/R-GGA-210805 Removal of miRNA passenger strand IEA Gallus gallus A0A1D5P6Q6 R-GGA-426464 https://reactome.org/PathwayBrowser/#/R-GGA-426464 Dicer cleaves double-stranded RNA to yield double-stranded siRNA IEA Gallus gallus A0A1D5P6Q6 R-GGA-9835358 https://reactome.org/PathwayBrowser/#/R-GGA-9835358 p-TARBP2 binds PKR IEA Gallus gallus A0A1D5P6Q7 R-GGA-416559 https://reactome.org/PathwayBrowser/#/R-GGA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Gallus gallus A0A1D5P6Q7 R-GGA-416562 https://reactome.org/PathwayBrowser/#/R-GGA-416562 p190RhoGAP binds Plexin-B1 IEA Gallus gallus A0A1D5P6Q7 R-GGA-8849082 https://reactome.org/PathwayBrowser/#/R-GGA-8849082 ARHGAP35 stimulates RHOA GTPase activity IEA Gallus gallus A0A1D5P6Q7 R-GGA-8849085 https://reactome.org/PathwayBrowser/#/R-GGA-8849085 ARHGAP35 binds RHOA:GTP IEA Gallus gallus A0A1D5P6Q7 R-GGA-8849094 https://reactome.org/PathwayBrowser/#/R-GGA-8849094 ARHGAP35 binds RASA1 IEA Gallus gallus A0A1D5P6Q7 R-GGA-8981353 https://reactome.org/PathwayBrowser/#/R-GGA-8981353 RASA1 stimulates RAS GTPase activity IEA Gallus gallus A0A1D5P6Q7 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus A0A1D5P6Q7 R-GGA-9013022 https://reactome.org/PathwayBrowser/#/R-GGA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Gallus gallus A0A1D5P6Q7 R-GGA-9013111 https://reactome.org/PathwayBrowser/#/R-GGA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Gallus gallus A0A1D5P6Q7 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus A0A1D5P6Q7 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus A0A1D5P6Q7 R-GGA-9013437 https://reactome.org/PathwayBrowser/#/R-GGA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Gallus gallus A0A1D5P6Q7 R-GGA-9014295 https://reactome.org/PathwayBrowser/#/R-GGA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Gallus gallus A0A1D5P6Q7 R-GGA-9014434 https://reactome.org/PathwayBrowser/#/R-GGA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Gallus gallus A0A1D5P6Q7 R-GGA-9017488 https://reactome.org/PathwayBrowser/#/R-GGA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Gallus gallus A0A1D5P6Q7 R-GGA-9018745 https://reactome.org/PathwayBrowser/#/R-GGA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Gallus gallus A0A1D5P6Q7 R-GGA-9018806 https://reactome.org/PathwayBrowser/#/R-GGA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Gallus gallus A0A1D5P6Q7 R-GGA-9696266 https://reactome.org/PathwayBrowser/#/R-GGA-9696266 RND2 binds effectors IEA Gallus gallus A0A1D5P6Q7 R-GGA-9696268 https://reactome.org/PathwayBrowser/#/R-GGA-9696268 RND3 binds effectors IEA Gallus gallus A0A1D5P6Q7 R-GGA-9696271 https://reactome.org/PathwayBrowser/#/R-GGA-9696271 RND1 binds effectors IEA Gallus gallus A0A1D5P6Q8 R-GGA-198818 https://reactome.org/PathwayBrowser/#/R-GGA-198818 SLC2A1,3 transports DeHA from extracellular region to cytosol IEA Gallus gallus A0A1D5P6Q8 R-GGA-450088 https://reactome.org/PathwayBrowser/#/R-GGA-450088 GLUT1 tetramer binds 4xATP IEA Gallus gallus A0A1D5P6Q8 R-GGA-450092 https://reactome.org/PathwayBrowser/#/R-GGA-450092 GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP IEA Gallus gallus A0A1D5P6Q8 R-GGA-499981 https://reactome.org/PathwayBrowser/#/R-GGA-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Gallus gallus A0A1D5P6Q8 R-GGA-5339524 https://reactome.org/PathwayBrowser/#/R-GGA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Gallus gallus A0A1D5P6Q8 R-GGA-5653873 https://reactome.org/PathwayBrowser/#/R-GGA-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Gallus gallus A0A1D5P6T3 R-GGA-110011 https://reactome.org/PathwayBrowser/#/R-GGA-110011 Binding of Grb10 to the insulin receptor IEA Gallus gallus A0A1D5P6T3 R-GGA-74707 https://reactome.org/PathwayBrowser/#/R-GGA-74707 Binding of IRS to insulin receptor IEA Gallus gallus A0A1D5P6T3 R-GGA-74711 https://reactome.org/PathwayBrowser/#/R-GGA-74711 Phosphorylation of IRS IEA Gallus gallus A0A1D5P6T3 R-GGA-74712 https://reactome.org/PathwayBrowser/#/R-GGA-74712 Dissociation of IRS-P from insulin receptor IEA Gallus gallus A0A1D5P6T3 R-GGA-74715 https://reactome.org/PathwayBrowser/#/R-GGA-74715 Autophosphorylation of insulin receptor IEA Gallus gallus A0A1D5P6T3 R-GGA-74716 https://reactome.org/PathwayBrowser/#/R-GGA-74716 Insulin binds the insulin receptor IEA Gallus gallus A0A1D5P6T3 R-GGA-74718 https://reactome.org/PathwayBrowser/#/R-GGA-74718 Internalisation of the insulin receptor IEA Gallus gallus A0A1D5P6T3 R-GGA-74726 https://reactome.org/PathwayBrowser/#/R-GGA-74726 Dissociation of insulin from insulin receptor IEA Gallus gallus A0A1D5P6T3 R-GGA-74733 https://reactome.org/PathwayBrowser/#/R-GGA-74733 Insulin receptor de-phosphorylation IEA Gallus gallus A0A1D5P6T3 R-GGA-74734 https://reactome.org/PathwayBrowser/#/R-GGA-74734 Re-integration of insulin receptor into plasma membrane IEA Gallus gallus A0A1D5P6T3 R-GGA-74740 https://reactome.org/PathwayBrowser/#/R-GGA-74740 Binding of SHC1 to insulin receptor IEA Gallus gallus A0A1D5P6T3 R-GGA-74742 https://reactome.org/PathwayBrowser/#/R-GGA-74742 Phosphorylation of SHC1 IEA Gallus gallus A0A1D5P6T3 R-GGA-74743 https://reactome.org/PathwayBrowser/#/R-GGA-74743 Dissociation of p-Y427-SHC1 from insulin receptor IEA Gallus gallus A0A1D5P6T6 R-GGA-8952996 https://reactome.org/PathwayBrowser/#/R-GGA-8952996 E2F7 forms homodimers IEA Gallus gallus A0A1D5P6T7 R-GGA-419001 https://reactome.org/PathwayBrowser/#/R-GGA-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Gallus gallus A0A1D5P6T7 R-GGA-419002 https://reactome.org/PathwayBrowser/#/R-GGA-419002 Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin IEA Gallus gallus A0A1D5P6T7 R-GGA-9759522 https://reactome.org/PathwayBrowser/#/R-GGA-9759522 Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform IEA Gallus gallus A0A1D5P6T7 R-GGA-9761421 https://reactome.org/PathwayBrowser/#/R-GGA-9761421 CDH11 associates with catenins IEA Gallus gallus A0A1D5P6T7 R-GGA-9761474 https://reactome.org/PathwayBrowser/#/R-GGA-9761474 AMOT-2 binds CDH11 IEA Gallus gallus A0A1D5P6T7 R-GGA-9762246 https://reactome.org/PathwayBrowser/#/R-GGA-9762246 ANGPTL4 binds CDH11 IEA Gallus gallus A0A1D5P6T7 R-GGA-9762282 https://reactome.org/PathwayBrowser/#/R-GGA-9762282 CTNNB1 dissociates from CDH11 upon ANGPTL4 binding IEA Gallus gallus A0A1D5P6T7 R-GGA-9762333 https://reactome.org/PathwayBrowser/#/R-GGA-9762333 ANGPTL4 binds to CDH11v IEA Gallus gallus A0A1D5P6V1 R-GGA-1602466 https://reactome.org/PathwayBrowser/#/R-GGA-1602466 Activation of MT-MMPs by FURIN IEA Gallus gallus A0A1D5P6V1 R-GGA-1605825 https://reactome.org/PathwayBrowser/#/R-GGA-1605825 MT-MMPs are sorted to the plasma membrane IEA Gallus gallus A0A1D5P6V5 R-GGA-6814670 https://reactome.org/PathwayBrowser/#/R-GGA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Gallus gallus A0A1D5P6V5 R-GGA-6814675 https://reactome.org/PathwayBrowser/#/R-GGA-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Gallus gallus A0A1D5P6V5 R-GGA-8848355 https://reactome.org/PathwayBrowser/#/R-GGA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Gallus gallus A0A1D5P6V5 R-GGA-9706390 https://reactome.org/PathwayBrowser/#/R-GGA-9706390 RHOBTB3 binds interacting proteins at trans-Golgi network IEA Gallus gallus A0A1D5P6W8 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus A0A1D5P6W8 R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus A0A1D5P6W8 R-GGA-5625849 https://reactome.org/PathwayBrowser/#/R-GGA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Gallus gallus A0A1D5P6W8 R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus A0A1D5P6W8 R-GGA-9011984 https://reactome.org/PathwayBrowser/#/R-GGA-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Gallus gallus A0A1D5P6W8 R-GGA-9011985 https://reactome.org/PathwayBrowser/#/R-GGA-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Gallus gallus A0A1D5P6W8 R-GGA-9679787 https://reactome.org/PathwayBrowser/#/R-GGA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Gallus gallus A0A1D5P6W8 R-GGA-996727 https://reactome.org/PathwayBrowser/#/R-GGA-996727 REST recruits the BHC complex IEA Gallus gallus A0A1D5P6W9 R-GGA-5173005 https://reactome.org/PathwayBrowser/#/R-GGA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Gallus gallus A0A1D5P6W9 R-GGA-5173192 https://reactome.org/PathwayBrowser/#/R-GGA-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Gallus gallus A0A1D5P6Z0 R-GGA-5173005 https://reactome.org/PathwayBrowser/#/R-GGA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Gallus gallus A0A1D5P6Z0 R-GGA-5173192 https://reactome.org/PathwayBrowser/#/R-GGA-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Gallus gallus A0A1D5P703 R-GGA-189053 https://reactome.org/PathwayBrowser/#/R-GGA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Gallus gallus A0A1D5P703 R-GGA-189069 https://reactome.org/PathwayBrowser/#/R-GGA-189069 sucrose + H2O => glucose + fructose IEA Gallus gallus A0A1D5P703 R-GGA-191101 https://reactome.org/PathwayBrowser/#/R-GGA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Gallus gallus A0A1D5P703 R-GGA-191108 https://reactome.org/PathwayBrowser/#/R-GGA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Gallus gallus A0A1D5P703 R-GGA-5659861 https://reactome.org/PathwayBrowser/#/R-GGA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Gallus gallus A0A1D5P711 R-GGA-5631903 https://reactome.org/PathwayBrowser/#/R-GGA-5631903 SESN1,2,3 bind overoxidized PRDX1 IEA Gallus gallus A0A1D5P711 R-GGA-5631941 https://reactome.org/PathwayBrowser/#/R-GGA-5631941 SESN1,2,3 bind AMPK IEA Gallus gallus A0A1D5P711 R-GGA-9639287 https://reactome.org/PathwayBrowser/#/R-GGA-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Gallus gallus A0A1D5P711 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus A0A1D5P711 R-GGA-9766645 https://reactome.org/PathwayBrowser/#/R-GGA-9766645 CUL3:RBX1 ubiquitinates KEAP1 IEA Gallus gallus A0A1D5P711 R-GGA-9766656 https://reactome.org/PathwayBrowser/#/R-GGA-9766656 RBX1:CUL3 dissociates from forming autophagosome IEA Gallus gallus A0A1D5P711 R-GGA-9766677 https://reactome.org/PathwayBrowser/#/R-GGA-9766677 MAP1LC3B binds KEAP1 and SQSTM1 IEA Gallus gallus A0A1D5P711 R-GGA-9766687 https://reactome.org/PathwayBrowser/#/R-GGA-9766687 SESN1,SESN1 bind SQSTM1 and KEAP1 IEA Gallus gallus A0A1D5P714 R-GGA-1013012 https://reactome.org/PathwayBrowser/#/R-GGA-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Gallus gallus A0A1D5P714 R-GGA-1013013 https://reactome.org/PathwayBrowser/#/R-GGA-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Gallus gallus A0A1D5P714 R-GGA-1013020 https://reactome.org/PathwayBrowser/#/R-GGA-1013020 Activation of GIRK/Kir3 Channels IEA Gallus gallus A0A1D5P714 R-GGA-112271 https://reactome.org/PathwayBrowser/#/R-GGA-112271 The receptor:G-protein complex dissociates IEA Gallus gallus A0A1D5P714 R-GGA-114552 https://reactome.org/PathwayBrowser/#/R-GGA-114552 Thrombin-activated PARs activate G12/13 IEA Gallus gallus A0A1D5P714 R-GGA-114558 https://reactome.org/PathwayBrowser/#/R-GGA-114558 Thrombin-activated PARs activate Gq IEA Gallus gallus A0A1D5P714 R-GGA-167408 https://reactome.org/PathwayBrowser/#/R-GGA-167408 The high affinity receptor complex binds to G-protein IEA Gallus gallus A0A1D5P714 R-GGA-167419 https://reactome.org/PathwayBrowser/#/R-GGA-167419 The receptor:G-protein complex releases GDP IEA Gallus gallus A0A1D5P714 R-GGA-167429 https://reactome.org/PathwayBrowser/#/R-GGA-167429 The receptor:G-protein complex binds GTP IEA Gallus gallus A0A1D5P714 R-GGA-167433 https://reactome.org/PathwayBrowser/#/R-GGA-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Gallus gallus A0A1D5P714 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus A0A1D5P714 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1D5P714 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5P714 R-GGA-392195 https://reactome.org/PathwayBrowser/#/R-GGA-392195 Gi activation by P2Y purinoceptor 12 IEA Gallus gallus A0A1D5P714 R-GGA-392295 https://reactome.org/PathwayBrowser/#/R-GGA-392295 Gbeta:gamma recruits PI3K gamma IEA Gallus gallus A0A1D5P714 R-GGA-392300 https://reactome.org/PathwayBrowser/#/R-GGA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Gallus gallus A0A1D5P714 R-GGA-3965444 https://reactome.org/PathwayBrowser/#/R-GGA-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Gallus gallus A0A1D5P714 R-GGA-3965447 https://reactome.org/PathwayBrowser/#/R-GGA-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Gallus gallus A0A1D5P714 R-GGA-396996 https://reactome.org/PathwayBrowser/#/R-GGA-396996 Thrombin-activated PARs binds G-protein Gq IEA Gallus gallus A0A1D5P714 R-GGA-397835 https://reactome.org/PathwayBrowser/#/R-GGA-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Gallus gallus A0A1D5P714 R-GGA-397891 https://reactome.org/PathwayBrowser/#/R-GGA-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Gallus gallus A0A1D5P714 R-GGA-398040 https://reactome.org/PathwayBrowser/#/R-GGA-398040 Gbeta:gamma activation of PLC beta IEA Gallus gallus A0A1D5P714 R-GGA-398193 https://reactome.org/PathwayBrowser/#/R-GGA-398193 PLC beta-mediated PIP2 hydrolysis IEA Gallus gallus A0A1D5P714 R-GGA-418576 https://reactome.org/PathwayBrowser/#/R-GGA-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Gallus gallus A0A1D5P714 R-GGA-420883 https://reactome.org/PathwayBrowser/#/R-GGA-420883 Opsins act as GEFs for G alpha-t IEA Gallus gallus A0A1D5P714 R-GGA-428749 https://reactome.org/PathwayBrowser/#/R-GGA-428749 Activated TP receptor binds G-proten Gq IEA Gallus gallus A0A1D5P714 R-GGA-428750 https://reactome.org/PathwayBrowser/#/R-GGA-428750 Gq activation by TP receptor IEA Gallus gallus A0A1D5P714 R-GGA-428752 https://reactome.org/PathwayBrowser/#/R-GGA-428752 Dissociation of the TP:Gq complex IEA Gallus gallus A0A1D5P714 R-GGA-428909 https://reactome.org/PathwayBrowser/#/R-GGA-428909 Activated TP receptor binds G-protein G13 IEA Gallus gallus A0A1D5P714 R-GGA-428917 https://reactome.org/PathwayBrowser/#/R-GGA-428917 G13 activation by TP receptor IEA Gallus gallus A0A1D5P714 R-GGA-428918 https://reactome.org/PathwayBrowser/#/R-GGA-428918 Dissociation of the TP:G13 complex IEA Gallus gallus A0A1D5P714 R-GGA-500717 https://reactome.org/PathwayBrowser/#/R-GGA-500717 Activation of GRIK3 homomer IEA Gallus gallus A0A1D5P714 R-GGA-6814119 https://reactome.org/PathwayBrowser/#/R-GGA-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Gallus gallus A0A1D5P714 R-GGA-6814120 https://reactome.org/PathwayBrowser/#/R-GGA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Gallus gallus A0A1D5P714 R-GGA-6814121 https://reactome.org/PathwayBrowser/#/R-GGA-6814121 PDCL binds G-protein beta and TRiC/CCT IEA Gallus gallus A0A1D5P714 R-GGA-6814124 https://reactome.org/PathwayBrowser/#/R-GGA-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Gallus gallus A0A1D5P714 R-GGA-749446 https://reactome.org/PathwayBrowser/#/R-GGA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Gallus gallus A0A1D5P714 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1D5P714 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1D5P714 R-GGA-749453 https://reactome.org/PathwayBrowser/#/R-GGA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Gallus gallus A0A1D5P714 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5P714 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5P714 R-GGA-750988 https://reactome.org/PathwayBrowser/#/R-GGA-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Gallus gallus A0A1D5P714 R-GGA-750993 https://reactome.org/PathwayBrowser/#/R-GGA-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Gallus gallus A0A1D5P714 R-GGA-751001 https://reactome.org/PathwayBrowser/#/R-GGA-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Gallus gallus A0A1D5P714 R-GGA-751019 https://reactome.org/PathwayBrowser/#/R-GGA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Gallus gallus A0A1D5P714 R-GGA-751024 https://reactome.org/PathwayBrowser/#/R-GGA-751024 The Ligand:GPCR:Gz complex dissociates IEA Gallus gallus A0A1D5P714 R-GGA-751027 https://reactome.org/PathwayBrowser/#/R-GGA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Gallus gallus A0A1D5P714 R-GGA-751029 https://reactome.org/PathwayBrowser/#/R-GGA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Gallus gallus A0A1D5P714 R-GGA-751039 https://reactome.org/PathwayBrowser/#/R-GGA-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Gallus gallus A0A1D5P714 R-GGA-8850529 https://reactome.org/PathwayBrowser/#/R-GGA-8850529 RGS proteins bind GNB5 and CCT/TRiC IEA Gallus gallus A0A1D5P714 R-GGA-8850534 https://reactome.org/PathwayBrowser/#/R-GGA-8850534 PDCL promotes G-protein beta 5 folding IEA Gallus gallus A0A1D5P714 R-GGA-8850539 https://reactome.org/PathwayBrowser/#/R-GGA-8850539 Release of GNB5:RGS dimers from CCT/TRiC IEA Gallus gallus A0A1D5P714 R-GGA-8964241 https://reactome.org/PathwayBrowser/#/R-GGA-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Gallus gallus A0A1D5P714 R-GGA-8964271 https://reactome.org/PathwayBrowser/#/R-GGA-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Gallus gallus A0A1D5P714 R-GGA-8964317 https://reactome.org/PathwayBrowser/#/R-GGA-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Gallus gallus A0A1D5P714 R-GGA-8964599 https://reactome.org/PathwayBrowser/#/R-GGA-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Gallus gallus A0A1D5P714 R-GGA-8964604 https://reactome.org/PathwayBrowser/#/R-GGA-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Gallus gallus A0A1D5P714 R-GGA-8964605 https://reactome.org/PathwayBrowser/#/R-GGA-8964605 PAK1:ARHGEF6 complex binds G-protein beta-gamma complex IEA Gallus gallus A0A1D5P714 R-GGA-8964614 https://reactome.org/PathwayBrowser/#/R-GGA-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Gallus gallus A0A1D5P714 R-GGA-8964634 https://reactome.org/PathwayBrowser/#/R-GGA-8964634 CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex IEA Gallus gallus A0A1D5P714 R-GGA-8982637 https://reactome.org/PathwayBrowser/#/R-GGA-8982637 Opsins binds G alpha-t IEA Gallus gallus A0A1D5P714 R-GGA-8982640 https://reactome.org/PathwayBrowser/#/R-GGA-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Gallus gallus A0A1D5P714 R-GGA-9021596 https://reactome.org/PathwayBrowser/#/R-GGA-9021596 Membrane estrogen receptors bind SRC IEA Gallus gallus A0A1D5P714 R-GGA-9021600 https://reactome.org/PathwayBrowser/#/R-GGA-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Gallus gallus A0A1D5P714 R-GGA-9021601 https://reactome.org/PathwayBrowser/#/R-GGA-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Gallus gallus A0A1D5P714 R-GGA-9036301 https://reactome.org/PathwayBrowser/#/R-GGA-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Gallus gallus A0A1D5P714 R-GGA-9036307 https://reactome.org/PathwayBrowser/#/R-GGA-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Gallus gallus A0A1D5P727 R-GGA-211951 https://reactome.org/PathwayBrowser/#/R-GGA-211951 CYP1B1 4-hydroxylates EST17b IEA Gallus gallus A0A1D5P727 R-GGA-2161795 https://reactome.org/PathwayBrowser/#/R-GGA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Gallus gallus A0A1D5P727 R-GGA-2161814 https://reactome.org/PathwayBrowser/#/R-GGA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Gallus gallus A0A1D5P727 R-GGA-2161890 https://reactome.org/PathwayBrowser/#/R-GGA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Gallus gallus A0A1D5P727 R-GGA-2161899 https://reactome.org/PathwayBrowser/#/R-GGA-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Gallus gallus A0A1D5P727 R-GGA-2161940 https://reactome.org/PathwayBrowser/#/R-GGA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Gallus gallus A0A1D5P727 R-GGA-9915971 https://reactome.org/PathwayBrowser/#/R-GGA-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Gallus gallus A0A1D5P727 R-GGA-9915992 https://reactome.org/PathwayBrowser/#/R-GGA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Gallus gallus A0A1D5P727 R-GGA-9915993 https://reactome.org/PathwayBrowser/#/R-GGA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Gallus gallus A0A1D5P727 R-GGA-9915997 https://reactome.org/PathwayBrowser/#/R-GGA-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Gallus gallus A0A1D5P736 R-GGA-6810235 https://reactome.org/PathwayBrowser/#/R-GGA-6810235 RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain IEA Gallus gallus A0A1D5P736 R-GGA-6814555 https://reactome.org/PathwayBrowser/#/R-GGA-6814555 Integrator complex processes the 3' end of snRNA IEA Gallus gallus A0A1D5P736 R-GGA-6814559 https://reactome.org/PathwayBrowser/#/R-GGA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Gallus gallus A0A1D5P747 R-GGA-8877620 https://reactome.org/PathwayBrowser/#/R-GGA-8877620 ECE2 cleaves EDN1(53-90) IEA Gallus gallus A0A1D5P756 R-GGA-5620914 https://reactome.org/PathwayBrowser/#/R-GGA-5620914 ARF4:GTP binds VxPx-motifs of membrane proteins IEA Gallus gallus A0A1D5P756 R-GGA-5620921 https://reactome.org/PathwayBrowser/#/R-GGA-5620921 ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex IEA Gallus gallus A0A1D5P756 R-GGA-5623513 https://reactome.org/PathwayBrowser/#/R-GGA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Gallus gallus A0A1D5P756 R-GGA-5623519 https://reactome.org/PathwayBrowser/#/R-GGA-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Gallus gallus A0A1D5P756 R-GGA-5623521 https://reactome.org/PathwayBrowser/#/R-GGA-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5P756 R-GGA-5623524 https://reactome.org/PathwayBrowser/#/R-GGA-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Gallus gallus A0A1D5P756 R-GGA-5623525 https://reactome.org/PathwayBrowser/#/R-GGA-5623525 Cargo-carrying vesicles bud from the TGN IEA Gallus gallus A0A1D5P756 R-GGA-5623527 https://reactome.org/PathwayBrowser/#/R-GGA-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Gallus gallus A0A1D5P760 R-GGA-5577234 https://reactome.org/PathwayBrowser/#/R-GGA-5577234 KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region IEA Gallus gallus A0A1D5P765 R-GGA-5693153 https://reactome.org/PathwayBrowser/#/R-GGA-5693153 PPM1K dephosphorylates p-BCKDH IEA Gallus gallus A0A1D5P765 R-GGA-9859148 https://reactome.org/PathwayBrowser/#/R-GGA-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Gallus gallus A0A1D5P765 R-GGA-9859163 https://reactome.org/PathwayBrowser/#/R-GGA-9859163 DBT transfers BCAA to CoA IEA Gallus gallus A0A1D5P765 R-GGA-9859172 https://reactome.org/PathwayBrowser/#/R-GGA-9859172 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus A0A1D5P770 R-GGA-3108203 https://reactome.org/PathwayBrowser/#/R-GGA-3108203 PRC1 SUMOylates CTBP1 with SUMO2,3 IEA Gallus gallus A0A1D5P770 R-GGA-3108209 https://reactome.org/PathwayBrowser/#/R-GGA-3108209 PRC1 SUMOylates CTBP1 with SUMO1 IEA Gallus gallus A0A1D5P770 R-GGA-3361751 https://reactome.org/PathwayBrowser/#/R-GGA-3361751 beta-catenin is replaced by repression complexes at the promoter IEA Gallus gallus A0A1D5P770 R-GGA-5334050 https://reactome.org/PathwayBrowser/#/R-GGA-5334050 TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes IEA Gallus gallus A0A1D5P774 R-GGA-983162 https://reactome.org/PathwayBrowser/#/R-GGA-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Gallus gallus A0A1D5P775 R-GGA-5610720 https://reactome.org/PathwayBrowser/#/R-GGA-5610720 PKA phosphorylates GLI3 IEA Gallus gallus A0A1D5P775 R-GGA-5610722 https://reactome.org/PathwayBrowser/#/R-GGA-5610722 CK1 phosphorylates p-GLI3 IEA Gallus gallus A0A1D5P775 R-GGA-5610723 https://reactome.org/PathwayBrowser/#/R-GGA-5610723 GLI proteins bind SUFU IEA Gallus gallus A0A1D5P775 R-GGA-5610732 https://reactome.org/PathwayBrowser/#/R-GGA-5610732 GSK3 phosphorylates p-GLI3 IEA Gallus gallus A0A1D5P775 R-GGA-5610746 https://reactome.org/PathwayBrowser/#/R-GGA-5610746 SCF(beta-TrCP) ubiquitinates p-GLI3 IEA Gallus gallus A0A1D5P775 R-GGA-5610752 https://reactome.org/PathwayBrowser/#/R-GGA-5610752 GLI3R translocates to the nucleus IEA Gallus gallus A0A1D5P775 R-GGA-5610754 https://reactome.org/PathwayBrowser/#/R-GGA-5610754 GLI3 is partially degraded by the proteasome to yield the GLI3 repressor IEA Gallus gallus A0A1D5P775 R-GGA-5610766 https://reactome.org/PathwayBrowser/#/R-GGA-5610766 The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base IEA Gallus gallus A0A1D5P775 R-GGA-5610767 https://reactome.org/PathwayBrowser/#/R-GGA-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Gallus gallus A0A1D5P775 R-GGA-5635843 https://reactome.org/PathwayBrowser/#/R-GGA-5635843 GLI translocates to the nucleus IEA Gallus gallus A0A1D5P775 R-GGA-5635845 https://reactome.org/PathwayBrowser/#/R-GGA-5635845 GLI proteins bind CDC73 IEA Gallus gallus A0A1D5P775 R-GGA-5635854 https://reactome.org/PathwayBrowser/#/R-GGA-5635854 GLI2,3 are degraded by the proteasome IEA Gallus gallus A0A1D5P775 R-GGA-5635855 https://reactome.org/PathwayBrowser/#/R-GGA-5635855 phosphorylated GLI proteins bind SPOP:CUL3:RBX1 IEA Gallus gallus A0A1D5P775 R-GGA-5635856 https://reactome.org/PathwayBrowser/#/R-GGA-5635856 SPOP:CUL3:RBX1 ubiquitinates GLI2,3 IEA Gallus gallus A0A1D5P775 R-GGA-5635859 https://reactome.org/PathwayBrowser/#/R-GGA-5635859 GLI:SUFU dissociates IEA Gallus gallus A0A1D5P775 R-GGA-5635860 https://reactome.org/PathwayBrowser/#/R-GGA-5635860 GLI:SUFU translocates to the ciliary tip in response to Hh signaling IEA Gallus gallus A0A1D5P786 R-GGA-6791222 https://reactome.org/PathwayBrowser/#/R-GGA-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Gallus gallus A0A1D5P786 R-GGA-6791227 https://reactome.org/PathwayBrowser/#/R-GGA-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Gallus gallus A0A1D5P790 R-GGA-8952630 https://reactome.org/PathwayBrowser/#/R-GGA-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P790 R-GGA-8952631 https://reactome.org/PathwayBrowser/#/R-GGA-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P790 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5P790 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5P790 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5P790 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5P790 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5P790 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5P7A9 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus A0A1D5P7A9 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus A0A1D5P7A9 R-GGA-5696968 https://reactome.org/PathwayBrowser/#/R-GGA-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Gallus gallus A0A1D5P7A9 R-GGA-8851797 https://reactome.org/PathwayBrowser/#/R-GGA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Gallus gallus A0A1D5P7A9 R-GGA-8982641 https://reactome.org/PathwayBrowser/#/R-GGA-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Gallus gallus A0A1D5P7A9 R-GGA-8982645 https://reactome.org/PathwayBrowser/#/R-GGA-8982645 GRKs bind ADRB2:Catecholamine IEA Gallus gallus A0A1D5P7A9 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus A0A1D5P7A9 R-GGA-9611751 https://reactome.org/PathwayBrowser/#/R-GGA-9611751 β1,2-agonists bind ADRB1,2 IEA Gallus gallus A0A1D5P7A9 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus A0A1D5P7A9 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus A0A1D5P7B5 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5P7B5 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5P7B5 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5P7B5 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5P7B5 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5P7C5 R-GGA-109638 https://reactome.org/PathwayBrowser/#/R-GGA-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Gallus gallus A0A1D5P7C5 R-GGA-109639 https://reactome.org/PathwayBrowser/#/R-GGA-109639 Formation of the closed pre-initiation complex IEA Gallus gallus A0A1D5P7C5 R-GGA-111264 https://reactome.org/PathwayBrowser/#/R-GGA-111264 Addition of nucleotides between position +11 and +30 IEA Gallus gallus A0A1D5P7C5 R-GGA-112381 https://reactome.org/PathwayBrowser/#/R-GGA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Gallus gallus A0A1D5P7C5 R-GGA-112383 https://reactome.org/PathwayBrowser/#/R-GGA-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Gallus gallus A0A1D5P7C5 R-GGA-112385 https://reactome.org/PathwayBrowser/#/R-GGA-112385 Addition of nucleotides leads to transcript elongation IEA Gallus gallus A0A1D5P7C5 R-GGA-112392 https://reactome.org/PathwayBrowser/#/R-GGA-112392 Resumption of elongation after recovery from pausing IEA Gallus gallus A0A1D5P7C5 R-GGA-112395 https://reactome.org/PathwayBrowser/#/R-GGA-112395 Abortive termination of elongation after arrest IEA Gallus gallus A0A1D5P7C5 R-GGA-112396 https://reactome.org/PathwayBrowser/#/R-GGA-112396 Separation of elongating transcript from template IEA Gallus gallus A0A1D5P7C5 R-GGA-113402 https://reactome.org/PathwayBrowser/#/R-GGA-113402 Formation of DSIF:NELF:early elongation complex IEA Gallus gallus A0A1D5P7C5 R-GGA-113409 https://reactome.org/PathwayBrowser/#/R-GGA-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Gallus gallus A0A1D5P7C5 R-GGA-113411 https://reactome.org/PathwayBrowser/#/R-GGA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Gallus gallus A0A1D5P7C5 R-GGA-113412 https://reactome.org/PathwayBrowser/#/R-GGA-113412 Pol II elongation complex moves on the template as transcript elongates IEA Gallus gallus A0A1D5P7C5 R-GGA-113413 https://reactome.org/PathwayBrowser/#/R-GGA-113413 TFIIS-mediated recovery of elongation from arrest IEA Gallus gallus A0A1D5P7C5 R-GGA-113414 https://reactome.org/PathwayBrowser/#/R-GGA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Gallus gallus A0A1D5P7C5 R-GGA-113430 https://reactome.org/PathwayBrowser/#/R-GGA-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Gallus gallus A0A1D5P7C5 R-GGA-5250930 https://reactome.org/PathwayBrowser/#/R-GGA-5250930 B-WICH recruits histone acetyltransferases IEA Gallus gallus A0A1D5P7C5 R-GGA-5250938 https://reactome.org/PathwayBrowser/#/R-GGA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Gallus gallus A0A1D5P7C5 R-GGA-5250947 https://reactome.org/PathwayBrowser/#/R-GGA-5250947 B-WICH complex binds rDNA promoter IEA Gallus gallus A0A1D5P7C5 R-GGA-5578742 https://reactome.org/PathwayBrowser/#/R-GGA-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Gallus gallus A0A1D5P7C5 R-GGA-6781818 https://reactome.org/PathwayBrowser/#/R-GGA-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Gallus gallus A0A1D5P7C5 R-GGA-6781824 https://reactome.org/PathwayBrowser/#/R-GGA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Gallus gallus A0A1D5P7C5 R-GGA-6781833 https://reactome.org/PathwayBrowser/#/R-GGA-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Gallus gallus A0A1D5P7C5 R-GGA-6781840 https://reactome.org/PathwayBrowser/#/R-GGA-6781840 ERCC6 binds stalled RNA Pol II IEA Gallus gallus A0A1D5P7C5 R-GGA-6781867 https://reactome.org/PathwayBrowser/#/R-GGA-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Gallus gallus A0A1D5P7C5 R-GGA-6782069 https://reactome.org/PathwayBrowser/#/R-GGA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Gallus gallus A0A1D5P7C5 R-GGA-6782131 https://reactome.org/PathwayBrowser/#/R-GGA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5P7C5 R-GGA-6782138 https://reactome.org/PathwayBrowser/#/R-GGA-6782138 ERCC5 and RPA bind TC-NER site IEA Gallus gallus A0A1D5P7C5 R-GGA-6782204 https://reactome.org/PathwayBrowser/#/R-GGA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Gallus gallus A0A1D5P7C5 R-GGA-6782208 https://reactome.org/PathwayBrowser/#/R-GGA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Gallus gallus A0A1D5P7C5 R-GGA-6782211 https://reactome.org/PathwayBrowser/#/R-GGA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Gallus gallus A0A1D5P7C5 R-GGA-6782227 https://reactome.org/PathwayBrowser/#/R-GGA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Gallus gallus A0A1D5P7C5 R-GGA-6797606 https://reactome.org/PathwayBrowser/#/R-GGA-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Gallus gallus A0A1D5P7C5 R-GGA-6797616 https://reactome.org/PathwayBrowser/#/R-GGA-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Gallus gallus A0A1D5P7C5 R-GGA-6803523 https://reactome.org/PathwayBrowser/#/R-GGA-6803523 PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA IEA Gallus gallus A0A1D5P7C5 R-GGA-6810233 https://reactome.org/PathwayBrowser/#/R-GGA-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Gallus gallus A0A1D5P7C5 R-GGA-6810235 https://reactome.org/PathwayBrowser/#/R-GGA-6810235 RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain IEA Gallus gallus A0A1D5P7C5 R-GGA-6810238 https://reactome.org/PathwayBrowser/#/R-GGA-6810238 RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) IEA Gallus gallus A0A1D5P7C5 R-GGA-6814555 https://reactome.org/PathwayBrowser/#/R-GGA-6814555 Integrator complex processes the 3' end of snRNA IEA Gallus gallus A0A1D5P7C5 R-GGA-6814559 https://reactome.org/PathwayBrowser/#/R-GGA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Gallus gallus A0A1D5P7C5 R-GGA-72095 https://reactome.org/PathwayBrowser/#/R-GGA-72095 Internal Methylation of mRNA IEA Gallus gallus A0A1D5P7C5 R-GGA-72103 https://reactome.org/PathwayBrowser/#/R-GGA-72103 Formation of pre-mRNPs IEA Gallus gallus A0A1D5P7C5 R-GGA-73757 https://reactome.org/PathwayBrowser/#/R-GGA-73757 Binding of RRN3 to RNA Polymerase I IEA Gallus gallus A0A1D5P7C5 R-GGA-73758 https://reactome.org/PathwayBrowser/#/R-GGA-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Gallus gallus A0A1D5P7C5 R-GGA-73769 https://reactome.org/PathwayBrowser/#/R-GGA-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Gallus gallus A0A1D5P7C5 R-GGA-73946 https://reactome.org/PathwayBrowser/#/R-GGA-73946 Abortive initiation after formation of the first phosphodiester bond IEA Gallus gallus A0A1D5P7C5 R-GGA-74986 https://reactome.org/PathwayBrowser/#/R-GGA-74986 Elongation of pre-rRNA transcript IEA Gallus gallus A0A1D5P7C5 R-GGA-74993 https://reactome.org/PathwayBrowser/#/R-GGA-74993 PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box IEA Gallus gallus A0A1D5P7C5 R-GGA-75079 https://reactome.org/PathwayBrowser/#/R-GGA-75079 Formation of AT-AC C complex IEA Gallus gallus A0A1D5P7C5 R-GGA-75081 https://reactome.org/PathwayBrowser/#/R-GGA-75081 Formation of AT-AC B Complex IEA Gallus gallus A0A1D5P7C5 R-GGA-75082 https://reactome.org/PathwayBrowser/#/R-GGA-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Gallus gallus A0A1D5P7C5 R-GGA-75083 https://reactome.org/PathwayBrowser/#/R-GGA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Gallus gallus A0A1D5P7C5 R-GGA-75095 https://reactome.org/PathwayBrowser/#/R-GGA-75095 Binding of TFIIE to the growing preinitiation complex IEA Gallus gallus A0A1D5P7C5 R-GGA-75850 https://reactome.org/PathwayBrowser/#/R-GGA-75850 Addition of the third nucleotide on the nascent transcript IEA Gallus gallus A0A1D5P7C5 R-GGA-75856 https://reactome.org/PathwayBrowser/#/R-GGA-75856 Abortive Initiation Before Second Transition IEA Gallus gallus A0A1D5P7C5 R-GGA-75861 https://reactome.org/PathwayBrowser/#/R-GGA-75861 NTP Binds Active Site of RNA Polymerase II IEA Gallus gallus A0A1D5P7C5 R-GGA-75862 https://reactome.org/PathwayBrowser/#/R-GGA-75862 Fall Back to Closed Pre-initiation Complex IEA Gallus gallus A0A1D5P7C5 R-GGA-75864 https://reactome.org/PathwayBrowser/#/R-GGA-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Gallus gallus A0A1D5P7C5 R-GGA-75866 https://reactome.org/PathwayBrowser/#/R-GGA-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Gallus gallus A0A1D5P7C5 R-GGA-75869 https://reactome.org/PathwayBrowser/#/R-GGA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Gallus gallus A0A1D5P7C5 R-GGA-75873 https://reactome.org/PathwayBrowser/#/R-GGA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Gallus gallus A0A1D5P7C5 R-GGA-75891 https://reactome.org/PathwayBrowser/#/R-GGA-75891 Abortive Initiation After Second Transition IEA Gallus gallus A0A1D5P7C5 R-GGA-75949 https://reactome.org/PathwayBrowser/#/R-GGA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Gallus gallus A0A1D5P7C5 R-GGA-76056 https://reactome.org/PathwayBrowser/#/R-GGA-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Gallus gallus A0A1D5P7C5 R-GGA-76576 https://reactome.org/PathwayBrowser/#/R-GGA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Gallus gallus A0A1D5P7C5 R-GGA-77068 https://reactome.org/PathwayBrowser/#/R-GGA-77068 Activation of GT IEA Gallus gallus A0A1D5P7C5 R-GGA-77069 https://reactome.org/PathwayBrowser/#/R-GGA-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Gallus gallus A0A1D5P7C5 R-GGA-77071 https://reactome.org/PathwayBrowser/#/R-GGA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Gallus gallus A0A1D5P7C5 R-GGA-77077 https://reactome.org/PathwayBrowser/#/R-GGA-77077 Capping complex formation IEA Gallus gallus A0A1D5P7C5 R-GGA-77078 https://reactome.org/PathwayBrowser/#/R-GGA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Gallus gallus A0A1D5P7C5 R-GGA-77081 https://reactome.org/PathwayBrowser/#/R-GGA-77081 Formation of the CE:GMP intermediate complex IEA Gallus gallus A0A1D5P7C5 R-GGA-77083 https://reactome.org/PathwayBrowser/#/R-GGA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Gallus gallus A0A1D5P7C5 R-GGA-77085 https://reactome.org/PathwayBrowser/#/R-GGA-77085 Dissociation of transcript with 5'-GMP from GT IEA Gallus gallus A0A1D5P7C5 R-GGA-77095 https://reactome.org/PathwayBrowser/#/R-GGA-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Gallus gallus A0A1D5P7C5 R-GGA-83803 https://reactome.org/PathwayBrowser/#/R-GGA-83803 Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex IEA Gallus gallus A0A1D5P7C5 R-GGA-83805 https://reactome.org/PathwayBrowser/#/R-GGA-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Gallus gallus A0A1D5P7C5 R-GGA-9012315 https://reactome.org/PathwayBrowser/#/R-GGA-9012315 ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene IEA Gallus gallus A0A1D5P7C5 R-GGA-9012319 https://reactome.org/PathwayBrowser/#/R-GGA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Gallus gallus A0A1D5P7C5 R-GGA-9613494 https://reactome.org/PathwayBrowser/#/R-GGA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Gallus gallus A0A1D5P7C5 R-GGA-9613497 https://reactome.org/PathwayBrowser/#/R-GGA-9613497 Unwinding DNA for the nascent transcript IEA Gallus gallus A0A1D5P7C5 R-GGA-9684118 https://reactome.org/PathwayBrowser/#/R-GGA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5P7C5 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5P7C6 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5P7C8 R-GGA-1482781 https://reactome.org/PathwayBrowser/#/R-GGA-1482781 MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) IEA Gallus gallus A0A1D5P7C8 R-GGA-1482794 https://reactome.org/PathwayBrowser/#/R-GGA-1482794 CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) IEA Gallus gallus A0A1D5P7C8 R-GGA-1482850 https://reactome.org/PathwayBrowser/#/R-GGA-1482850 MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) IEA Gallus gallus A0A1D5P7C8 R-GGA-1482894 https://reactome.org/PathwayBrowser/#/R-GGA-1482894 CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) IEA Gallus gallus A0A1D5P7C8 R-GGA-1955380 https://reactome.org/PathwayBrowser/#/R-GGA-1955380 TIMM9:TIMM10 transfers proteins to TIMM22 IEA Gallus gallus A0A1D5P7D0 R-GGA-380508 https://reactome.org/PathwayBrowser/#/R-GGA-380508 Translocation of NuMA to the centrosomes IEA Gallus gallus A0A1D5P7D9 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus A0A1D5P7E4 R-GGA-3134946 https://reactome.org/PathwayBrowser/#/R-GGA-3134946 DDX41 ubiquitination by TRIM21 IEA Gallus gallus A0A1D5P7E4 R-GGA-9013869 https://reactome.org/PathwayBrowser/#/R-GGA-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Gallus gallus A0A1D5P7E8 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus A0A1D5P7E8 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus A0A1D5P7E8 R-GGA-5694417 https://reactome.org/PathwayBrowser/#/R-GGA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Gallus gallus A0A1D5P7H9 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5P7H9 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5P7H9 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus A0A1D5P7I0 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A1D5P7I0 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A1D5P7I0 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A1D5P7I0 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A1D5P7I0 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5P7I0 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5P7I0 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5P7I0 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5P7I0 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5P7I0 R-GGA-2574840 https://reactome.org/PathwayBrowser/#/R-GGA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Gallus gallus A0A1D5P7I0 R-GGA-2574845 https://reactome.org/PathwayBrowser/#/R-GGA-2574845 AJUBA binds centrosome-associated AURKA IEA Gallus gallus A0A1D5P7I0 R-GGA-3000310 https://reactome.org/PathwayBrowser/#/R-GGA-3000310 AURKA phosphorylates PLK1 IEA Gallus gallus A0A1D5P7I0 R-GGA-3000319 https://reactome.org/PathwayBrowser/#/R-GGA-3000319 BORA binds PLK1 and AURKA IEA Gallus gallus A0A1D5P7I0 R-GGA-380272 https://reactome.org/PathwayBrowser/#/R-GGA-380272 Plk1-mediated phosphorylation of Nlp IEA Gallus gallus A0A1D5P7I0 R-GGA-380283 https://reactome.org/PathwayBrowser/#/R-GGA-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Gallus gallus A0A1D5P7I0 R-GGA-380294 https://reactome.org/PathwayBrowser/#/R-GGA-380294 Loss of C-Nap-1 from centrosomes IEA Gallus gallus A0A1D5P7I0 R-GGA-380311 https://reactome.org/PathwayBrowser/#/R-GGA-380311 Recruitment of Plk1 to centrosomes IEA Gallus gallus A0A1D5P7I0 R-GGA-380455 https://reactome.org/PathwayBrowser/#/R-GGA-380455 Recruitment of CDK11p58 to the centrosomes IEA Gallus gallus A0A1D5P7I0 R-GGA-380508 https://reactome.org/PathwayBrowser/#/R-GGA-380508 Translocation of NuMA to the centrosomes IEA Gallus gallus A0A1D5P7I0 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5P7I0 R-GGA-5626228 https://reactome.org/PathwayBrowser/#/R-GGA-5626228 The distal appendage proteins recruit TTBK2 IEA Gallus gallus A0A1D5P7I0 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1D5P7I0 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1D5P7I0 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A1D5P7I0 R-GGA-8853405 https://reactome.org/PathwayBrowser/#/R-GGA-8853405 TPX2 binds AURKA at centrosomes IEA Gallus gallus A0A1D5P7I0 R-GGA-8853419 https://reactome.org/PathwayBrowser/#/R-GGA-8853419 TPX2 promotes AURKA autophosphorylation IEA Gallus gallus A0A1D5P7I0 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1D5P7K5 R-GGA-198870 https://reactome.org/PathwayBrowser/#/R-GGA-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Gallus gallus A0A1D5P7K7 R-GGA-5692770 https://reactome.org/PathwayBrowser/#/R-GGA-5692770 SEPT7 binds p-S189 MAPK6 and p-T182 MAPKAPK5 IEA Gallus gallus A0A1D5P7K7 R-GGA-5692775 https://reactome.org/PathwayBrowser/#/R-GGA-5692775 SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs IEA Gallus gallus A0A1D5P7L0 R-GGA-8932980 https://reactome.org/PathwayBrowser/#/R-GGA-8932980 SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane IEA Gallus gallus A0A1D5P7L1 R-GGA-5336443 https://reactome.org/PathwayBrowser/#/R-GGA-5336443 LIN7, CASK and APBA1 bind IEA Gallus gallus A0A1D5P7L1 R-GGA-6797553 https://reactome.org/PathwayBrowser/#/R-GGA-6797553 Protein 4.1 binds CASK IEA Gallus gallus A0A1D5P7M3 R-GGA-5652005 https://reactome.org/PathwayBrowser/#/R-GGA-5652005 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA IEA Gallus gallus A0A1D5P7M3 R-GGA-5652009 https://reactome.org/PathwayBrowser/#/R-GGA-5652009 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA IEA Gallus gallus A0A1D5P7M3 R-GGA-5689317 https://reactome.org/PathwayBrowser/#/R-GGA-5689317 Formation of the pre-incision complex in GG-NER IEA Gallus gallus A0A1D5P7M3 R-GGA-5689861 https://reactome.org/PathwayBrowser/#/R-GGA-5689861 Recruitment of XPA and release of CAK IEA Gallus gallus A0A1D5P7M3 R-GGA-5690213 https://reactome.org/PathwayBrowser/#/R-GGA-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Gallus gallus A0A1D5P7M3 R-GGA-5690990 https://reactome.org/PathwayBrowser/#/R-GGA-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Gallus gallus A0A1D5P7M3 R-GGA-5690996 https://reactome.org/PathwayBrowser/#/R-GGA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Gallus gallus A0A1D5P7M3 R-GGA-5691000 https://reactome.org/PathwayBrowser/#/R-GGA-5691000 TFIIH binds GG-NER site to form a verification complex IEA Gallus gallus A0A1D5P7M3 R-GGA-5691006 https://reactome.org/PathwayBrowser/#/R-GGA-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Gallus gallus A0A1D5P7M3 R-GGA-5696655 https://reactome.org/PathwayBrowser/#/R-GGA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Gallus gallus A0A1D5P7M3 R-GGA-5696664 https://reactome.org/PathwayBrowser/#/R-GGA-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Gallus gallus A0A1D5P7M3 R-GGA-5696670 https://reactome.org/PathwayBrowser/#/R-GGA-5696670 CHD1L is recruited to GG-NER site IEA Gallus gallus A0A1D5P7M3 R-GGA-6781833 https://reactome.org/PathwayBrowser/#/R-GGA-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Gallus gallus A0A1D5P7M3 R-GGA-6781867 https://reactome.org/PathwayBrowser/#/R-GGA-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Gallus gallus A0A1D5P7M3 R-GGA-6782069 https://reactome.org/PathwayBrowser/#/R-GGA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Gallus gallus A0A1D5P7M3 R-GGA-6782131 https://reactome.org/PathwayBrowser/#/R-GGA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5P7M3 R-GGA-6782138 https://reactome.org/PathwayBrowser/#/R-GGA-6782138 ERCC5 and RPA bind TC-NER site IEA Gallus gallus A0A1D5P7M3 R-GGA-6782204 https://reactome.org/PathwayBrowser/#/R-GGA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Gallus gallus A0A1D5P7M3 R-GGA-6782208 https://reactome.org/PathwayBrowser/#/R-GGA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Gallus gallus A0A1D5P7M3 R-GGA-6782211 https://reactome.org/PathwayBrowser/#/R-GGA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Gallus gallus A0A1D5P7M3 R-GGA-6782227 https://reactome.org/PathwayBrowser/#/R-GGA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Gallus gallus A0A1D5P7M3 R-GGA-6782943 https://reactome.org/PathwayBrowser/#/R-GGA-6782943 UV-DDB ubiquitinates XPC IEA Gallus gallus A0A1D5P7M3 R-GGA-6790454 https://reactome.org/PathwayBrowser/#/R-GGA-6790454 SUMOylation of XPC IEA Gallus gallus A0A1D5P7M3 R-GGA-6790487 https://reactome.org/PathwayBrowser/#/R-GGA-6790487 RNF111 ubiquitinates SUMOylated XPC IEA Gallus gallus A0A1D5P7M3 R-GGA-8952638 https://reactome.org/PathwayBrowser/#/R-GGA-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P7M3 R-GGA-8952639 https://reactome.org/PathwayBrowser/#/R-GGA-8952639 NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P7M3 R-GGA-8955245 https://reactome.org/PathwayBrowser/#/R-GGA-8955245 CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus IEA Gallus gallus A0A1D5P7M3 R-GGA-8956045 https://reactome.org/PathwayBrowser/#/R-GGA-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P7M3 R-GGA-9684118 https://reactome.org/PathwayBrowser/#/R-GGA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5P7N2 R-GGA-418456 https://reactome.org/PathwayBrowser/#/R-GGA-418456 cGMP is degraded by PDEs IEA Gallus gallus A0A1D5P7N2 R-GGA-418553 https://reactome.org/PathwayBrowser/#/R-GGA-418553 cAMP degradation by Phosphodiesterases IEA Gallus gallus A0A1D5P7P2 R-GGA-8862700 https://reactome.org/PathwayBrowser/#/R-GGA-8862700 CMKLR1 binds Resolvin E1 IEA Gallus gallus A0A1D5P7Q2 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus A0A1D5P7Q2 R-GGA-391935 https://reactome.org/PathwayBrowser/#/R-GGA-391935 DP1 receptor can bind PGD2 IEA Gallus gallus A0A1D5P7Q3 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5P7Q3 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5P7Q3 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5P7Q3 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5P7Q3 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5P7R6 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1D5P7R6 R-GGA-391939 https://reactome.org/PathwayBrowser/#/R-GGA-391939 TP receptor can bind thromboxane IEA Gallus gallus A0A1D5P7R6 R-GGA-428749 https://reactome.org/PathwayBrowser/#/R-GGA-428749 Activated TP receptor binds G-proten Gq IEA Gallus gallus A0A1D5P7R6 R-GGA-428750 https://reactome.org/PathwayBrowser/#/R-GGA-428750 Gq activation by TP receptor IEA Gallus gallus A0A1D5P7R6 R-GGA-428752 https://reactome.org/PathwayBrowser/#/R-GGA-428752 Dissociation of the TP:Gq complex IEA Gallus gallus A0A1D5P7R6 R-GGA-428909 https://reactome.org/PathwayBrowser/#/R-GGA-428909 Activated TP receptor binds G-protein G13 IEA Gallus gallus A0A1D5P7R6 R-GGA-428917 https://reactome.org/PathwayBrowser/#/R-GGA-428917 G13 activation by TP receptor IEA Gallus gallus A0A1D5P7R6 R-GGA-428918 https://reactome.org/PathwayBrowser/#/R-GGA-428918 Dissociation of the TP:G13 complex IEA Gallus gallus A0A1D5P7R6 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1D5P7R6 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1D5P7R6 R-GGA-751019 https://reactome.org/PathwayBrowser/#/R-GGA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Gallus gallus A0A1D5P7R6 R-GGA-751027 https://reactome.org/PathwayBrowser/#/R-GGA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Gallus gallus A0A1D5P7R6 R-GGA-751029 https://reactome.org/PathwayBrowser/#/R-GGA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Gallus gallus A0A1D5P7R6 R-GGA-9674529 https://reactome.org/PathwayBrowser/#/R-GGA-9674529 AAMP binds to TBXA2R IEA Gallus gallus A0A1D5P7T5 R-GGA-1296127 https://reactome.org/PathwayBrowser/#/R-GGA-1296127 Activation of voltage gated Potassium channels IEA Gallus gallus A0A1D5P7U7 R-GGA-75079 https://reactome.org/PathwayBrowser/#/R-GGA-75079 Formation of AT-AC C complex IEA Gallus gallus A0A1D5P7U7 R-GGA-75081 https://reactome.org/PathwayBrowser/#/R-GGA-75081 Formation of AT-AC B Complex IEA Gallus gallus A0A1D5P7U7 R-GGA-75082 https://reactome.org/PathwayBrowser/#/R-GGA-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Gallus gallus A0A1D5P7U7 R-GGA-75083 https://reactome.org/PathwayBrowser/#/R-GGA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Gallus gallus A0A1D5P7V7 R-GGA-1362408 https://reactome.org/PathwayBrowser/#/R-GGA-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Gallus gallus A0A1D5P7V7 R-GGA-1362416 https://reactome.org/PathwayBrowser/#/R-GGA-1362416 Frataxin binds iron IEA Gallus gallus A0A1D5P7V7 R-GGA-947514 https://reactome.org/PathwayBrowser/#/R-GGA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 IEA Gallus gallus A0A1D5P7V7 R-GGA-9866272 https://reactome.org/PathwayBrowser/#/R-GGA-9866272 2Fe-2S is inserted in UQCRFS1 IEA Gallus gallus A0A1D5P7W0 R-GGA-111439 https://reactome.org/PathwayBrowser/#/R-GGA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Gallus gallus A0A1D5P7W0 R-GGA-158441 https://reactome.org/PathwayBrowser/#/R-GGA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5P7W0 R-GGA-158447 https://reactome.org/PathwayBrowser/#/R-GGA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Gallus gallus A0A1D5P7W0 R-GGA-158481 https://reactome.org/PathwayBrowser/#/R-GGA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5P7W0 R-GGA-158484 https://reactome.org/PathwayBrowser/#/R-GGA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Gallus gallus A0A1D5P7W0 R-GGA-159046 https://reactome.org/PathwayBrowser/#/R-GGA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Gallus gallus A0A1D5P7W0 R-GGA-159050 https://reactome.org/PathwayBrowser/#/R-GGA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Gallus gallus A0A1D5P7W0 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1D5P7W0 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1D5P7W0 R-GGA-77587 https://reactome.org/PathwayBrowser/#/R-GGA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Gallus gallus A0A1D5P7W1 R-GGA-6789031 https://reactome.org/PathwayBrowser/#/R-GGA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus A0A1D5P7W1 R-GGA-6789126 https://reactome.org/PathwayBrowser/#/R-GGA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus A0A1D5P7W1 R-GGA-6789136 https://reactome.org/PathwayBrowser/#/R-GGA-6789136 Myeloperoxidase (MPO) binds to the bacterial cell surface IEA Gallus gallus A0A1D5P7W1 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5P7W1 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5P7W1 R-GGA-8855490 https://reactome.org/PathwayBrowser/#/R-GGA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Gallus gallus A0A1D5P7W1 R-GGA-8933635 https://reactome.org/PathwayBrowser/#/R-GGA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Gallus gallus A0A1D5P7W7 R-GGA-265177 https://reactome.org/PathwayBrowser/#/R-GGA-265177 Exocyst complex formation IEA Gallus gallus A0A1D5P7W7 R-GGA-5623524 https://reactome.org/PathwayBrowser/#/R-GGA-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Gallus gallus A0A1D5P7W7 R-GGA-5623527 https://reactome.org/PathwayBrowser/#/R-GGA-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Gallus gallus A0A1D5P7W8 R-GGA-164832 https://reactome.org/PathwayBrowser/#/R-GGA-164832 ATPase synthesizes ATP IEA Gallus gallus A0A1D5P7W8 R-GGA-164834 https://reactome.org/PathwayBrowser/#/R-GGA-164834 Enzyme-bound ATP is released IEA Gallus gallus A0A1D5P7W8 R-GGA-164840 https://reactome.org/PathwayBrowser/#/R-GGA-164840 ADP and Pi bind to ATPase IEA Gallus gallus A0A1D5P7W8 R-GGA-8949580 https://reactome.org/PathwayBrowser/#/R-GGA-8949580 F1Fo ATP synthase dimerizes IEA Gallus gallus A0A1D5P7X1 R-GGA-421831 https://reactome.org/PathwayBrowser/#/R-GGA-421831 trans-Golgi Network Coat Assembly IEA Gallus gallus A0A1D5P7X1 R-GGA-421835 https://reactome.org/PathwayBrowser/#/R-GGA-421835 trans-Golgi Network Vesicle Scission IEA Gallus gallus A0A1D5P7X1 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5P7X1 R-GGA-6814670 https://reactome.org/PathwayBrowser/#/R-GGA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Gallus gallus A0A1D5P7X1 R-GGA-6814671 https://reactome.org/PathwayBrowser/#/R-GGA-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Gallus gallus A0A1D5P7X1 R-GGA-6814675 https://reactome.org/PathwayBrowser/#/R-GGA-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Gallus gallus A0A1D5P7X1 R-GGA-8866277 https://reactome.org/PathwayBrowser/#/R-GGA-8866277 AP-2 directly binds some endocytic cargo IEA Gallus gallus A0A1D5P7X1 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5P7X1 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5P7X1 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5P7X1 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5P7X1 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5P7X1 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5P7X1 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5P7X1 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5P7X1 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P7X1 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P7X1 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5P7X1 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5P7X9 R-GGA-164651 https://reactome.org/PathwayBrowser/#/R-GGA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Gallus gallus A0A1D5P7X9 R-GGA-9906042 https://reactome.org/PathwayBrowser/#/R-GGA-9906042 TTC19 clears UQCRFS1 fragments from Complex III IEA Gallus gallus A0A1D5P7Y1 R-GGA-8952638 https://reactome.org/PathwayBrowser/#/R-GGA-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P7Y1 R-GGA-8952639 https://reactome.org/PathwayBrowser/#/R-GGA-8952639 NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P7Y1 R-GGA-8955245 https://reactome.org/PathwayBrowser/#/R-GGA-8955245 CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus IEA Gallus gallus A0A1D5P7Y1 R-GGA-8956045 https://reactome.org/PathwayBrowser/#/R-GGA-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P7Y8 R-GGA-177479 https://reactome.org/PathwayBrowser/#/R-GGA-177479 Axonal transport of NGF:Trk complexes IEA Gallus gallus A0A1D5P7Y8 R-GGA-2130725 https://reactome.org/PathwayBrowser/#/R-GGA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Gallus gallus A0A1D5P7Y8 R-GGA-392749 https://reactome.org/PathwayBrowser/#/R-GGA-392749 Transport of L1 into endosomes IEA Gallus gallus A0A1D5P7Y8 R-GGA-3928654 https://reactome.org/PathwayBrowser/#/R-GGA-3928654 Clathrin internalises EPH:EFN complexes IEA Gallus gallus A0A1D5P7Y8 R-GGA-416639 https://reactome.org/PathwayBrowser/#/R-GGA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Gallus gallus A0A1D5P7Y8 R-GGA-445079 https://reactome.org/PathwayBrowser/#/R-GGA-445079 Phosphorylation of L1 by ERK IEA Gallus gallus A0A1D5P7Y8 R-GGA-5140747 https://reactome.org/PathwayBrowser/#/R-GGA-5140747 FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner IEA Gallus gallus A0A1D5P7Y8 R-GGA-555065 https://reactome.org/PathwayBrowser/#/R-GGA-555065 Formation of clathrin coated vesicle IEA Gallus gallus A0A1D5P7Y8 R-GGA-6784729 https://reactome.org/PathwayBrowser/#/R-GGA-6784729 PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome IEA Gallus gallus A0A1D5P7Y8 R-GGA-6784738 https://reactome.org/PathwayBrowser/#/R-GGA-6784738 Degradation of PCSK9:LDLR:Clathrin-coated vesicle IEA Gallus gallus A0A1D5P7Y8 R-GGA-8855130 https://reactome.org/PathwayBrowser/#/R-GGA-8855130 VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane IEA Gallus gallus A0A1D5P7Y8 R-GGA-8855131 https://reactome.org/PathwayBrowser/#/R-GGA-8855131 VLDLR:PCSK9 binds Clathrin-coated vesicles IEA Gallus gallus A0A1D5P7Y8 R-GGA-8856813 https://reactome.org/PathwayBrowser/#/R-GGA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Gallus gallus A0A1D5P7Y8 R-GGA-8866277 https://reactome.org/PathwayBrowser/#/R-GGA-8866277 AP-2 directly binds some endocytic cargo IEA Gallus gallus A0A1D5P7Y8 R-GGA-8866279 https://reactome.org/PathwayBrowser/#/R-GGA-8866279 Epsin family proteins bind ubiquitinated cargo IEA Gallus gallus A0A1D5P7Y8 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5P7Y8 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5P7Y8 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5P7Y8 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5P7Y8 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5P7Y8 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5P7Y8 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5P7Y8 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5P7Y8 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P7Y8 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P7Y8 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5P7Y8 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5P7Y8 R-GGA-8871196 https://reactome.org/PathwayBrowser/#/R-GGA-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Gallus gallus A0A1D5P7Y8 R-GGA-9681616 https://reactome.org/PathwayBrowser/#/R-GGA-9681616 AP2 binds chlorpromazine IEA Gallus gallus A0A1D5P7Z5 R-GGA-1013012 https://reactome.org/PathwayBrowser/#/R-GGA-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Gallus gallus A0A1D5P7Z5 R-GGA-1013013 https://reactome.org/PathwayBrowser/#/R-GGA-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Gallus gallus A0A1D5P7Z5 R-GGA-1013020 https://reactome.org/PathwayBrowser/#/R-GGA-1013020 Activation of GIRK/Kir3 Channels IEA Gallus gallus A0A1D5P7Z5 R-GGA-112271 https://reactome.org/PathwayBrowser/#/R-GGA-112271 The receptor:G-protein complex dissociates IEA Gallus gallus A0A1D5P7Z5 R-GGA-114552 https://reactome.org/PathwayBrowser/#/R-GGA-114552 Thrombin-activated PARs activate G12/13 IEA Gallus gallus A0A1D5P7Z5 R-GGA-114558 https://reactome.org/PathwayBrowser/#/R-GGA-114558 Thrombin-activated PARs activate Gq IEA Gallus gallus A0A1D5P7Z5 R-GGA-167408 https://reactome.org/PathwayBrowser/#/R-GGA-167408 The high affinity receptor complex binds to G-protein IEA Gallus gallus A0A1D5P7Z5 R-GGA-167419 https://reactome.org/PathwayBrowser/#/R-GGA-167419 The receptor:G-protein complex releases GDP IEA Gallus gallus A0A1D5P7Z5 R-GGA-167429 https://reactome.org/PathwayBrowser/#/R-GGA-167429 The receptor:G-protein complex binds GTP IEA Gallus gallus A0A1D5P7Z5 R-GGA-167433 https://reactome.org/PathwayBrowser/#/R-GGA-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Gallus gallus A0A1D5P7Z5 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus A0A1D5P7Z5 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1D5P7Z5 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5P7Z5 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus A0A1D5P7Z5 R-GGA-392195 https://reactome.org/PathwayBrowser/#/R-GGA-392195 Gi activation by P2Y purinoceptor 12 IEA Gallus gallus A0A1D5P7Z5 R-GGA-392295 https://reactome.org/PathwayBrowser/#/R-GGA-392295 Gbeta:gamma recruits PI3K gamma IEA Gallus gallus A0A1D5P7Z5 R-GGA-392300 https://reactome.org/PathwayBrowser/#/R-GGA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Gallus gallus A0A1D5P7Z5 R-GGA-3965444 https://reactome.org/PathwayBrowser/#/R-GGA-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Gallus gallus A0A1D5P7Z5 R-GGA-3965447 https://reactome.org/PathwayBrowser/#/R-GGA-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Gallus gallus A0A1D5P7Z5 R-GGA-396996 https://reactome.org/PathwayBrowser/#/R-GGA-396996 Thrombin-activated PARs binds G-protein Gq IEA Gallus gallus A0A1D5P7Z5 R-GGA-397835 https://reactome.org/PathwayBrowser/#/R-GGA-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Gallus gallus A0A1D5P7Z5 R-GGA-397891 https://reactome.org/PathwayBrowser/#/R-GGA-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Gallus gallus A0A1D5P7Z5 R-GGA-398040 https://reactome.org/PathwayBrowser/#/R-GGA-398040 Gbeta:gamma activation of PLC beta IEA Gallus gallus A0A1D5P7Z5 R-GGA-398193 https://reactome.org/PathwayBrowser/#/R-GGA-398193 PLC beta-mediated PIP2 hydrolysis IEA Gallus gallus A0A1D5P7Z5 R-GGA-418576 https://reactome.org/PathwayBrowser/#/R-GGA-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Gallus gallus A0A1D5P7Z5 R-GGA-420883 https://reactome.org/PathwayBrowser/#/R-GGA-420883 Opsins act as GEFs for G alpha-t IEA Gallus gallus A0A1D5P7Z5 R-GGA-428749 https://reactome.org/PathwayBrowser/#/R-GGA-428749 Activated TP receptor binds G-proten Gq IEA Gallus gallus A0A1D5P7Z5 R-GGA-428750 https://reactome.org/PathwayBrowser/#/R-GGA-428750 Gq activation by TP receptor IEA Gallus gallus A0A1D5P7Z5 R-GGA-428752 https://reactome.org/PathwayBrowser/#/R-GGA-428752 Dissociation of the TP:Gq complex IEA Gallus gallus A0A1D5P7Z5 R-GGA-428909 https://reactome.org/PathwayBrowser/#/R-GGA-428909 Activated TP receptor binds G-protein G13 IEA Gallus gallus A0A1D5P7Z5 R-GGA-428917 https://reactome.org/PathwayBrowser/#/R-GGA-428917 G13 activation by TP receptor IEA Gallus gallus A0A1D5P7Z5 R-GGA-428918 https://reactome.org/PathwayBrowser/#/R-GGA-428918 Dissociation of the TP:G13 complex IEA Gallus gallus A0A1D5P7Z5 R-GGA-500717 https://reactome.org/PathwayBrowser/#/R-GGA-500717 Activation of GRIK3 homomer IEA Gallus gallus A0A1D5P7Z5 R-GGA-6814119 https://reactome.org/PathwayBrowser/#/R-GGA-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Gallus gallus A0A1D5P7Z5 R-GGA-6814120 https://reactome.org/PathwayBrowser/#/R-GGA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Gallus gallus A0A1D5P7Z5 R-GGA-6814121 https://reactome.org/PathwayBrowser/#/R-GGA-6814121 PDCL binds G-protein beta and TRiC/CCT IEA Gallus gallus A0A1D5P7Z5 R-GGA-6814124 https://reactome.org/PathwayBrowser/#/R-GGA-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Gallus gallus A0A1D5P7Z5 R-GGA-6814418 https://reactome.org/PathwayBrowser/#/R-GGA-6814418 PDCL promotes formation of G-beta:G-gamma heterodimers IEA Gallus gallus A0A1D5P7Z5 R-GGA-749446 https://reactome.org/PathwayBrowser/#/R-GGA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Gallus gallus A0A1D5P7Z5 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1D5P7Z5 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1D5P7Z5 R-GGA-749453 https://reactome.org/PathwayBrowser/#/R-GGA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Gallus gallus A0A1D5P7Z5 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5P7Z5 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5P7Z5 R-GGA-750988 https://reactome.org/PathwayBrowser/#/R-GGA-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Gallus gallus A0A1D5P7Z5 R-GGA-750993 https://reactome.org/PathwayBrowser/#/R-GGA-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Gallus gallus A0A1D5P7Z5 R-GGA-751001 https://reactome.org/PathwayBrowser/#/R-GGA-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Gallus gallus A0A1D5P7Z5 R-GGA-751019 https://reactome.org/PathwayBrowser/#/R-GGA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Gallus gallus A0A1D5P7Z5 R-GGA-751024 https://reactome.org/PathwayBrowser/#/R-GGA-751024 The Ligand:GPCR:Gz complex dissociates IEA Gallus gallus A0A1D5P7Z5 R-GGA-751027 https://reactome.org/PathwayBrowser/#/R-GGA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Gallus gallus A0A1D5P7Z5 R-GGA-751029 https://reactome.org/PathwayBrowser/#/R-GGA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Gallus gallus A0A1D5P7Z5 R-GGA-751039 https://reactome.org/PathwayBrowser/#/R-GGA-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Gallus gallus A0A1D5P7Z5 R-GGA-8850527 https://reactome.org/PathwayBrowser/#/R-GGA-8850527 PDCL releases folded G-beta from TRiC/CCT IEA Gallus gallus A0A1D5P7Z5 R-GGA-8850560 https://reactome.org/PathwayBrowser/#/R-GGA-8850560 G-protein alpha releases G-protein heterotrimer from PDCL IEA Gallus gallus A0A1D5P7Z5 R-GGA-8964241 https://reactome.org/PathwayBrowser/#/R-GGA-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Gallus gallus A0A1D5P7Z5 R-GGA-8964271 https://reactome.org/PathwayBrowser/#/R-GGA-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Gallus gallus A0A1D5P7Z5 R-GGA-8964317 https://reactome.org/PathwayBrowser/#/R-GGA-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Gallus gallus A0A1D5P7Z5 R-GGA-8964599 https://reactome.org/PathwayBrowser/#/R-GGA-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Gallus gallus A0A1D5P7Z5 R-GGA-8964604 https://reactome.org/PathwayBrowser/#/R-GGA-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Gallus gallus A0A1D5P7Z5 R-GGA-8964605 https://reactome.org/PathwayBrowser/#/R-GGA-8964605 PAK1:ARHGEF6 complex binds G-protein beta-gamma complex IEA Gallus gallus A0A1D5P7Z5 R-GGA-8964614 https://reactome.org/PathwayBrowser/#/R-GGA-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Gallus gallus A0A1D5P7Z5 R-GGA-8964634 https://reactome.org/PathwayBrowser/#/R-GGA-8964634 CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex IEA Gallus gallus A0A1D5P7Z5 R-GGA-8982637 https://reactome.org/PathwayBrowser/#/R-GGA-8982637 Opsins binds G alpha-t IEA Gallus gallus A0A1D5P7Z5 R-GGA-8982640 https://reactome.org/PathwayBrowser/#/R-GGA-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Gallus gallus A0A1D5P7Z5 R-GGA-9021596 https://reactome.org/PathwayBrowser/#/R-GGA-9021596 Membrane estrogen receptors bind SRC IEA Gallus gallus A0A1D5P7Z5 R-GGA-9021600 https://reactome.org/PathwayBrowser/#/R-GGA-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Gallus gallus A0A1D5P7Z5 R-GGA-9021601 https://reactome.org/PathwayBrowser/#/R-GGA-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Gallus gallus A0A1D5P7Z5 R-GGA-9036301 https://reactome.org/PathwayBrowser/#/R-GGA-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Gallus gallus A0A1D5P7Z5 R-GGA-9036307 https://reactome.org/PathwayBrowser/#/R-GGA-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Gallus gallus A0A1D5P7Z5 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus A0A1D5P7Z9 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5P7Z9 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1D5P7Z9 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1D5P810 R-GGA-164832 https://reactome.org/PathwayBrowser/#/R-GGA-164832 ATPase synthesizes ATP IEA Gallus gallus A0A1D5P810 R-GGA-164834 https://reactome.org/PathwayBrowser/#/R-GGA-164834 Enzyme-bound ATP is released IEA Gallus gallus A0A1D5P810 R-GGA-164840 https://reactome.org/PathwayBrowser/#/R-GGA-164840 ADP and Pi bind to ATPase IEA Gallus gallus A0A1D5P810 R-GGA-8949580 https://reactome.org/PathwayBrowser/#/R-GGA-8949580 F1Fo ATP synthase dimerizes IEA Gallus gallus A0A1D5P810 R-GGA-9837978 https://reactome.org/PathwayBrowser/#/R-GGA-9837978 LONP1 binds mitochondrial inner membrane proteins IEA Gallus gallus A0A1D5P810 R-GGA-9838004 https://reactome.org/PathwayBrowser/#/R-GGA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Gallus gallus A0A1D5P857 R-GGA-4641205 https://reactome.org/PathwayBrowser/#/R-GGA-4641205 RSPO:LGR binds ZNRF3 IEA Gallus gallus A0A1D5P857 R-GGA-4641206 https://reactome.org/PathwayBrowser/#/R-GGA-4641206 RSPOs bind LGRs IEA Gallus gallus A0A1D5P857 R-GGA-4641246 https://reactome.org/PathwayBrowser/#/R-GGA-4641246 ZNRF3 autoubiquitinates to promote its internalization IEA Gallus gallus A0A1D5P875 R-GGA-9647991 https://reactome.org/PathwayBrowser/#/R-GGA-9647991 Palmostatin B binds RAS depalmitoylases IEA Gallus gallus A0A1D5P875 R-GGA-9647994 https://reactome.org/PathwayBrowser/#/R-GGA-9647994 RAS proteins are depalmitoylated IEA Gallus gallus A0A1D5P882 R-GGA-8863718 https://reactome.org/PathwayBrowser/#/R-GGA-8863718 AGFG1 binds VAMP7 IEA Gallus gallus A0A1D5P882 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5P882 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5P882 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5P882 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5P882 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5P882 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5P882 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5P882 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5P882 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P882 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P882 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5P882 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5P884 R-GGA-5173005 https://reactome.org/PathwayBrowser/#/R-GGA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Gallus gallus A0A1D5P884 R-GGA-5173192 https://reactome.org/PathwayBrowser/#/R-GGA-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Gallus gallus A0A1D5P899 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5P899 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5P899 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5P899 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5P899 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5P8A5 R-GGA-442317 https://reactome.org/PathwayBrowser/#/R-GGA-442317 ZIP6 and ZIP14 mediate zinc influx into cells IEA Gallus gallus A0A1D5P8A5 R-GGA-442387 https://reactome.org/PathwayBrowser/#/R-GGA-442387 ZIP8 mediates zinc influx into cells IEA Gallus gallus A0A1D5P8A7 R-GGA-72670 https://reactome.org/PathwayBrowser/#/R-GGA-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Gallus gallus A0A1D5P8A7 R-GGA-72722 https://reactome.org/PathwayBrowser/#/R-GGA-72722 eIF2 activation IEA Gallus gallus A0A1D5P8C1 R-GGA-109639 https://reactome.org/PathwayBrowser/#/R-GGA-109639 Formation of the closed pre-initiation complex IEA Gallus gallus A0A1D5P8C1 R-GGA-111264 https://reactome.org/PathwayBrowser/#/R-GGA-111264 Addition of nucleotides between position +11 and +30 IEA Gallus gallus A0A1D5P8C1 R-GGA-112383 https://reactome.org/PathwayBrowser/#/R-GGA-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Gallus gallus A0A1D5P8C1 R-GGA-112385 https://reactome.org/PathwayBrowser/#/R-GGA-112385 Addition of nucleotides leads to transcript elongation IEA Gallus gallus A0A1D5P8C1 R-GGA-113430 https://reactome.org/PathwayBrowser/#/R-GGA-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Gallus gallus A0A1D5P8C1 R-GGA-5689317 https://reactome.org/PathwayBrowser/#/R-GGA-5689317 Formation of the pre-incision complex in GG-NER IEA Gallus gallus A0A1D5P8C1 R-GGA-5689861 https://reactome.org/PathwayBrowser/#/R-GGA-5689861 Recruitment of XPA and release of CAK IEA Gallus gallus A0A1D5P8C1 R-GGA-5690213 https://reactome.org/PathwayBrowser/#/R-GGA-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Gallus gallus A0A1D5P8C1 R-GGA-5690990 https://reactome.org/PathwayBrowser/#/R-GGA-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Gallus gallus A0A1D5P8C1 R-GGA-5690996 https://reactome.org/PathwayBrowser/#/R-GGA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Gallus gallus A0A1D5P8C1 R-GGA-5691000 https://reactome.org/PathwayBrowser/#/R-GGA-5691000 TFIIH binds GG-NER site to form a verification complex IEA Gallus gallus A0A1D5P8C1 R-GGA-5696670 https://reactome.org/PathwayBrowser/#/R-GGA-5696670 CHD1L is recruited to GG-NER site IEA Gallus gallus A0A1D5P8C1 R-GGA-6781818 https://reactome.org/PathwayBrowser/#/R-GGA-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Gallus gallus A0A1D5P8C1 R-GGA-6781824 https://reactome.org/PathwayBrowser/#/R-GGA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Gallus gallus A0A1D5P8C1 R-GGA-6781833 https://reactome.org/PathwayBrowser/#/R-GGA-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Gallus gallus A0A1D5P8C1 R-GGA-6781840 https://reactome.org/PathwayBrowser/#/R-GGA-6781840 ERCC6 binds stalled RNA Pol II IEA Gallus gallus A0A1D5P8C1 R-GGA-6781867 https://reactome.org/PathwayBrowser/#/R-GGA-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Gallus gallus A0A1D5P8C1 R-GGA-6782069 https://reactome.org/PathwayBrowser/#/R-GGA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Gallus gallus A0A1D5P8C1 R-GGA-6782131 https://reactome.org/PathwayBrowser/#/R-GGA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5P8C1 R-GGA-6782138 https://reactome.org/PathwayBrowser/#/R-GGA-6782138 ERCC5 and RPA bind TC-NER site IEA Gallus gallus A0A1D5P8C1 R-GGA-6782204 https://reactome.org/PathwayBrowser/#/R-GGA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Gallus gallus A0A1D5P8C1 R-GGA-6782208 https://reactome.org/PathwayBrowser/#/R-GGA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Gallus gallus A0A1D5P8C1 R-GGA-6782211 https://reactome.org/PathwayBrowser/#/R-GGA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Gallus gallus A0A1D5P8C1 R-GGA-6782227 https://reactome.org/PathwayBrowser/#/R-GGA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Gallus gallus A0A1D5P8C1 R-GGA-6790454 https://reactome.org/PathwayBrowser/#/R-GGA-6790454 SUMOylation of XPC IEA Gallus gallus A0A1D5P8C1 R-GGA-6790487 https://reactome.org/PathwayBrowser/#/R-GGA-6790487 RNF111 ubiquitinates SUMOylated XPC IEA Gallus gallus A0A1D5P8C1 R-GGA-6797606 https://reactome.org/PathwayBrowser/#/R-GGA-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Gallus gallus A0A1D5P8C1 R-GGA-6797616 https://reactome.org/PathwayBrowser/#/R-GGA-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Gallus gallus A0A1D5P8C1 R-GGA-73758 https://reactome.org/PathwayBrowser/#/R-GGA-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Gallus gallus A0A1D5P8C1 R-GGA-73769 https://reactome.org/PathwayBrowser/#/R-GGA-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Gallus gallus A0A1D5P8C1 R-GGA-73946 https://reactome.org/PathwayBrowser/#/R-GGA-73946 Abortive initiation after formation of the first phosphodiester bond IEA Gallus gallus A0A1D5P8C1 R-GGA-74986 https://reactome.org/PathwayBrowser/#/R-GGA-74986 Elongation of pre-rRNA transcript IEA Gallus gallus A0A1D5P8C1 R-GGA-74993 https://reactome.org/PathwayBrowser/#/R-GGA-74993 PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box IEA Gallus gallus A0A1D5P8C1 R-GGA-75850 https://reactome.org/PathwayBrowser/#/R-GGA-75850 Addition of the third nucleotide on the nascent transcript IEA Gallus gallus A0A1D5P8C1 R-GGA-75856 https://reactome.org/PathwayBrowser/#/R-GGA-75856 Abortive Initiation Before Second Transition IEA Gallus gallus A0A1D5P8C1 R-GGA-75861 https://reactome.org/PathwayBrowser/#/R-GGA-75861 NTP Binds Active Site of RNA Polymerase II IEA Gallus gallus A0A1D5P8C1 R-GGA-75862 https://reactome.org/PathwayBrowser/#/R-GGA-75862 Fall Back to Closed Pre-initiation Complex IEA Gallus gallus A0A1D5P8C1 R-GGA-75864 https://reactome.org/PathwayBrowser/#/R-GGA-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Gallus gallus A0A1D5P8C1 R-GGA-75866 https://reactome.org/PathwayBrowser/#/R-GGA-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Gallus gallus A0A1D5P8C1 R-GGA-75869 https://reactome.org/PathwayBrowser/#/R-GGA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Gallus gallus A0A1D5P8C1 R-GGA-75873 https://reactome.org/PathwayBrowser/#/R-GGA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Gallus gallus A0A1D5P8C1 R-GGA-75891 https://reactome.org/PathwayBrowser/#/R-GGA-75891 Abortive Initiation After Second Transition IEA Gallus gallus A0A1D5P8C1 R-GGA-75949 https://reactome.org/PathwayBrowser/#/R-GGA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Gallus gallus A0A1D5P8C1 R-GGA-76576 https://reactome.org/PathwayBrowser/#/R-GGA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Gallus gallus A0A1D5P8C1 R-GGA-77068 https://reactome.org/PathwayBrowser/#/R-GGA-77068 Activation of GT IEA Gallus gallus A0A1D5P8C1 R-GGA-77069 https://reactome.org/PathwayBrowser/#/R-GGA-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Gallus gallus A0A1D5P8C1 R-GGA-77071 https://reactome.org/PathwayBrowser/#/R-GGA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Gallus gallus A0A1D5P8C1 R-GGA-77077 https://reactome.org/PathwayBrowser/#/R-GGA-77077 Capping complex formation IEA Gallus gallus A0A1D5P8C1 R-GGA-77078 https://reactome.org/PathwayBrowser/#/R-GGA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Gallus gallus A0A1D5P8C1 R-GGA-77081 https://reactome.org/PathwayBrowser/#/R-GGA-77081 Formation of the CE:GMP intermediate complex IEA Gallus gallus A0A1D5P8C1 R-GGA-77083 https://reactome.org/PathwayBrowser/#/R-GGA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Gallus gallus A0A1D5P8C1 R-GGA-77085 https://reactome.org/PathwayBrowser/#/R-GGA-77085 Dissociation of transcript with 5'-GMP from GT IEA Gallus gallus A0A1D5P8C1 R-GGA-9613494 https://reactome.org/PathwayBrowser/#/R-GGA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Gallus gallus A0A1D5P8C1 R-GGA-9613497 https://reactome.org/PathwayBrowser/#/R-GGA-9613497 Unwinding DNA for the nascent transcript IEA Gallus gallus A0A1D5P8C1 R-GGA-9684118 https://reactome.org/PathwayBrowser/#/R-GGA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5P8D7 R-GGA-5610763 https://reactome.org/PathwayBrowser/#/R-GGA-5610763 PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal IEA Gallus gallus A0A1D5P8D7 R-GGA-5624126 https://reactome.org/PathwayBrowser/#/R-GGA-5624126 ARL6:GTP and the BBSome bind ciliary cargo IEA Gallus gallus A0A1D5P8D7 R-GGA-5624127 https://reactome.org/PathwayBrowser/#/R-GGA-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Gallus gallus A0A1D5P8D7 R-GGA-5633040 https://reactome.org/PathwayBrowser/#/R-GGA-5633040 CSNK1A1 and ADRBK1 dissociate from p-SMO dimer IEA Gallus gallus A0A1D5P8D7 R-GGA-5635859 https://reactome.org/PathwayBrowser/#/R-GGA-5635859 GLI:SUFU dissociates IEA Gallus gallus A0A1D5P8E2 R-GGA-939763 https://reactome.org/PathwayBrowser/#/R-GGA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Gallus gallus A0A1D5P8E2 R-GGA-947591 https://reactome.org/PathwayBrowser/#/R-GGA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Gallus gallus A0A1D5P8E8 R-GGA-114352 https://reactome.org/PathwayBrowser/#/R-GGA-114352 Sequestration of tBID by BCL-2 IEA Gallus gallus A0A1D5P8E8 R-GGA-139893 https://reactome.org/PathwayBrowser/#/R-GGA-139893 Granzyme-B activates BID by cleavage IEA Gallus gallus A0A1D5P8E8 R-GGA-139895 https://reactome.org/PathwayBrowser/#/R-GGA-139895 tBID activates BAK protein IEA Gallus gallus A0A1D5P8E8 R-GGA-139898 https://reactome.org/PathwayBrowser/#/R-GGA-139898 Caspase-8 activates BID by cleavage IEA Gallus gallus A0A1D5P8E8 R-GGA-139920 https://reactome.org/PathwayBrowser/#/R-GGA-139920 Translocation of tBID to mitochondria IEA Gallus gallus A0A1D5P8E8 R-GGA-141367 https://reactome.org/PathwayBrowser/#/R-GGA-141367 Myristoylation of tBID by NMT1 IEA Gallus gallus A0A1D5P8E8 R-GGA-168848 https://reactome.org/PathwayBrowser/#/R-GGA-168848 tBID binds to inactive BAK protein IEA Gallus gallus A0A1D5P8E8 R-GGA-508162 https://reactome.org/PathwayBrowser/#/R-GGA-508162 BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL IEA Gallus gallus A0A1D5P8G1 R-GGA-6799350 https://reactome.org/PathwayBrowser/#/R-GGA-6799350 Exocytosis of specific granule membrane proteins IEA Gallus gallus A0A1D5P8H7 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A1D5P8H7 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A1D5P8H7 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A1D5P8H7 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A1D5P8H7 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5P8H7 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5P8H7 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5P8H7 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5P8H7 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5P8H7 R-GGA-3769391 https://reactome.org/PathwayBrowser/#/R-GGA-3769391 XPO1 binds the beta-catenin:CBY complex IEA Gallus gallus A0A1D5P8H7 R-GGA-3769392 https://reactome.org/PathwayBrowser/#/R-GGA-3769392 YWHAZ and XPO1 mediate the nuclear export of beta-catenin IEA Gallus gallus A0A1D5P8H7 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A1D5P8H7 R-GGA-5687109 https://reactome.org/PathwayBrowser/#/R-GGA-5687109 MAPK4,6 translocate to the cytoplasm IEA Gallus gallus A0A1D5P8H7 R-GGA-9632873 https://reactome.org/PathwayBrowser/#/R-GGA-9632873 p-S10 CDKN1B translocates to the cytosol IEA Gallus gallus A0A1D5P8H7 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1D5P8H7 R-GGA-9708423 https://reactome.org/PathwayBrowser/#/R-GGA-9708423 XPO1:BACH1:Hemes are transported out of the nucleus IEA Gallus gallus A0A1D5P8H7 R-GGA-9708430 https://reactome.org/PathwayBrowser/#/R-GGA-9708430 XPO1 (CRM1) binds to BACH1:Hemes IEA Gallus gallus A0A1D5P8H7 R-GGA-9824979 https://reactome.org/PathwayBrowser/#/R-GGA-9824979 XPO1 binds p-S69,73 MITF-M IEA Gallus gallus A0A1D5P8H7 R-GGA-9824986 https://reactome.org/PathwayBrowser/#/R-GGA-9824986 XPO1-dependent export of p-S69,S73 MITF-M IEA Gallus gallus A0A1D5P8I7 R-GGA-450984 https://reactome.org/PathwayBrowser/#/R-GGA-450984 IDH2 dimer decarboxylates isocitrate IEA Gallus gallus A0A1D5P8I7 R-GGA-5688289 https://reactome.org/PathwayBrowser/#/R-GGA-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Gallus gallus A0A1D5P8I7 R-GGA-9854415 https://reactome.org/PathwayBrowser/#/R-GGA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Gallus gallus A0A1D5P8I7 R-GGA-9854463 https://reactome.org/PathwayBrowser/#/R-GGA-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Gallus gallus A0A1D5P8L1 R-GGA-174439 https://reactome.org/PathwayBrowser/#/R-GGA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Gallus gallus A0A1D5P8L1 R-GGA-174452 https://reactome.org/PathwayBrowser/#/R-GGA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Gallus gallus A0A1D5P8L1 R-GGA-9668902 https://reactome.org/PathwayBrowser/#/R-GGA-9668902 Formation of the CTF18-RFC(7s) complex IEA Gallus gallus A0A1D5P8L1 R-GGA-9668904 https://reactome.org/PathwayBrowser/#/R-GGA-9668904 Formation of the CTF18 complex IEA Gallus gallus A0A1D5P8N3 R-GGA-2130641 https://reactome.org/PathwayBrowser/#/R-GGA-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Gallus gallus A0A1D5P8N3 R-GGA-421831 https://reactome.org/PathwayBrowser/#/R-GGA-421831 trans-Golgi Network Coat Assembly IEA Gallus gallus A0A1D5P8N3 R-GGA-421835 https://reactome.org/PathwayBrowser/#/R-GGA-421835 trans-Golgi Network Vesicle Scission IEA Gallus gallus A0A1D5P8N3 R-GGA-432706 https://reactome.org/PathwayBrowser/#/R-GGA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Gallus gallus A0A1D5P8N3 R-GGA-432707 https://reactome.org/PathwayBrowser/#/R-GGA-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Gallus gallus A0A1D5P8N3 R-GGA-5333658 https://reactome.org/PathwayBrowser/#/R-GGA-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Gallus gallus A0A1D5P8N3 R-GGA-8951498 https://reactome.org/PathwayBrowser/#/R-GGA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Gallus gallus A0A1D5P8P1 R-GGA-264615 https://reactome.org/PathwayBrowser/#/R-GGA-264615 Loading of acetylcholine in synaptic vesicles IEA Gallus gallus A0A1D5P8P1 R-GGA-372505 https://reactome.org/PathwayBrowser/#/R-GGA-372505 Acetylcholine synaptic vesicle docking and priming IEA Gallus gallus A0A1D5P8P1 R-GGA-374922 https://reactome.org/PathwayBrowser/#/R-GGA-374922 Noradrenalin synaptic vesicle docking and priming IEA Gallus gallus A0A1D5P8P1 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5P8P1 R-GGA-8875318 https://reactome.org/PathwayBrowser/#/R-GGA-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Gallus gallus A0A1D5P8P3 R-GGA-1454757 https://reactome.org/PathwayBrowser/#/R-GGA-1454757 Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 IEA Gallus gallus A0A1D5P8P3 R-GGA-1564142 https://reactome.org/PathwayBrowser/#/R-GGA-1564142 Collagen type IV degradation by MMP2,3,4,9,10,12 IEA Gallus gallus A0A1D5P8P3 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus A0A1D5P8P3 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus A0A1D5P8P3 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus A0A1D5P8P3 R-GGA-1981120 https://reactome.org/PathwayBrowser/#/R-GGA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Gallus gallus A0A1D5P8P3 R-GGA-2002460 https://reactome.org/PathwayBrowser/#/R-GGA-2002460 P4HB binds Collagen chains IEA Gallus gallus A0A1D5P8P3 R-GGA-2089971 https://reactome.org/PathwayBrowser/#/R-GGA-2089971 Secretion of collagens IEA Gallus gallus A0A1D5P8P3 R-GGA-2213207 https://reactome.org/PathwayBrowser/#/R-GGA-2213207 Formation of collagen networks IEA Gallus gallus A0A1D5P8P3 R-GGA-2559639 https://reactome.org/PathwayBrowser/#/R-GGA-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Gallus gallus A0A1D5P8P3 R-GGA-382054 https://reactome.org/PathwayBrowser/#/R-GGA-382054 PDGF binds to extracellular matrix proteins IEA Gallus gallus A0A1D5P8P3 R-GGA-4084912 https://reactome.org/PathwayBrowser/#/R-GGA-4084912 Arresten binds integrin alpha1beta1 IEA Gallus gallus A0A1D5P8P3 R-GGA-8948228 https://reactome.org/PathwayBrowser/#/R-GGA-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Gallus gallus A0A1D5P8P3 R-GGA-8948231 https://reactome.org/PathwayBrowser/#/R-GGA-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Gallus gallus A0A1D5P8P3 R-GGA-8948232 https://reactome.org/PathwayBrowser/#/R-GGA-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Gallus gallus A0A1D5P8P3 R-GGA-8948234 https://reactome.org/PathwayBrowser/#/R-GGA-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Gallus gallus A0A1D5P8Q1 R-GGA-5685318 https://reactome.org/PathwayBrowser/#/R-GGA-5685318 BCDX2 complex formation IEA Gallus gallus A0A1D5P8Q1 R-GGA-5685341 https://reactome.org/PathwayBrowser/#/R-GGA-5685341 BCDX2 complex stabilizes RAD51 filament IEA Gallus gallus A0A1D5P8Q1 R-GGA-5685838 https://reactome.org/PathwayBrowser/#/R-GGA-5685838 CX3 complex binds D-loop structures IEA Gallus gallus A0A1D5P8Q1 R-GGA-5693539 https://reactome.org/PathwayBrowser/#/R-GGA-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Gallus gallus A0A1D5P8Q1 R-GGA-5693584 https://reactome.org/PathwayBrowser/#/R-GGA-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Gallus gallus A0A1D5P8Q1 R-GGA-5693593 https://reactome.org/PathwayBrowser/#/R-GGA-5693593 D-loop extension by DNA polymerases IEA Gallus gallus A0A1D5P8Q1 R-GGA-5693620 https://reactome.org/PathwayBrowser/#/R-GGA-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Gallus gallus A0A1D5P8Q1 R-GGA-9853389 https://reactome.org/PathwayBrowser/#/R-GGA-9853389 FIGNL1 binds RAD51 IEA Gallus gallus A0A1D5P8R6 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1D5P8S6 R-GGA-6798747 https://reactome.org/PathwayBrowser/#/R-GGA-6798747 Exocytosis of tertiary granule membrane proteins IEA Gallus gallus A0A1D5P8S7 R-GGA-9033235 https://reactome.org/PathwayBrowser/#/R-GGA-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1D5P8S7 R-GGA-9033236 https://reactome.org/PathwayBrowser/#/R-GGA-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Gallus gallus A0A1D5P8S7 R-GGA-9033520 https://reactome.org/PathwayBrowser/#/R-GGA-9033520 TYSND1 cleaves TYSND1 IEA Gallus gallus A0A1D5P8S9 R-GGA-2025890 https://reactome.org/PathwayBrowser/#/R-GGA-2025890 Calcineurin binds NFATC1,2,3 IEA Gallus gallus A0A1D5P8S9 R-GGA-2730849 https://reactome.org/PathwayBrowser/#/R-GGA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Gallus gallus A0A1D5P8S9 R-GGA-2730867 https://reactome.org/PathwayBrowser/#/R-GGA-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Gallus gallus A0A1D5P8U4 R-GGA-373061 https://reactome.org/PathwayBrowser/#/R-GGA-373061 Receptors CCR3, 4 and 5 bind CCL5 ligand IEA Gallus gallus A0A1D5P8U4 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5P8U4 R-GGA-443986 https://reactome.org/PathwayBrowser/#/R-GGA-443986 Receptor ACKR2 binds most inflammatory CC chemokines IEA Gallus gallus A0A1D5P8U4 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5P8U4 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5P8W2 R-GGA-212380 https://reactome.org/PathwayBrowser/#/R-GGA-212380 Formation of TRAP coactivator complex IEA Gallus gallus A0A1D5P8W2 R-GGA-212432 https://reactome.org/PathwayBrowser/#/R-GGA-212432 Formation of DRIP coactivator complex IEA Gallus gallus A0A1D5P8W2 R-GGA-9843120 https://reactome.org/PathwayBrowser/#/R-GGA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1D5P8X6 R-GGA-174425 https://reactome.org/PathwayBrowser/#/R-GGA-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Gallus gallus A0A1D5P8X6 R-GGA-174427 https://reactome.org/PathwayBrowser/#/R-GGA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Gallus gallus A0A1D5P8X6 R-GGA-174452 https://reactome.org/PathwayBrowser/#/R-GGA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Gallus gallus A0A1D5P8X6 R-GGA-9668831 https://reactome.org/PathwayBrowser/#/R-GGA-9668831 CST complex formation IEA Gallus gallus A0A1D5P8X9 R-GGA-8867613 https://reactome.org/PathwayBrowser/#/R-GGA-8867613 PICALM binds R-SNAREs IEA Gallus gallus A0A1D5P8X9 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5P8X9 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5P8X9 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5P8X9 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5P8X9 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5P8X9 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5P8X9 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5P8X9 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5P8X9 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P8X9 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5P8X9 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5P8X9 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5P8Y9 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus A0A1D5P8Y9 R-GGA-388596 https://reactome.org/PathwayBrowser/#/R-GGA-388596 Melanocortin receptors bind melanocortins IEA Gallus gallus A0A1D5P8Z1 R-GGA-1878002 https://reactome.org/PathwayBrowser/#/R-GGA-1878002 XYLTs transfer Xyl to core protein IEA Gallus gallus A0A1D5P8Z1 R-GGA-1889955 https://reactome.org/PathwayBrowser/#/R-GGA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Gallus gallus A0A1D5P8Z1 R-GGA-1889981 https://reactome.org/PathwayBrowser/#/R-GGA-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Gallus gallus A0A1D5P8Z1 R-GGA-1971482 https://reactome.org/PathwayBrowser/#/R-GGA-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Gallus gallus A0A1D5P8Z1 R-GGA-1971483 https://reactome.org/PathwayBrowser/#/R-GGA-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Gallus gallus A0A1D5P8Z1 R-GGA-1971487 https://reactome.org/PathwayBrowser/#/R-GGA-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Gallus gallus A0A1D5P8Z1 R-GGA-1971491 https://reactome.org/PathwayBrowser/#/R-GGA-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Gallus gallus A0A1D5P8Z1 R-GGA-2018659 https://reactome.org/PathwayBrowser/#/R-GGA-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Gallus gallus A0A1D5P8Z1 R-GGA-2018682 https://reactome.org/PathwayBrowser/#/R-GGA-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Gallus gallus A0A1D5P8Z1 R-GGA-2022052 https://reactome.org/PathwayBrowser/#/R-GGA-2022052 Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS) IEA Gallus gallus A0A1D5P8Z1 R-GGA-2022056 https://reactome.org/PathwayBrowser/#/R-GGA-2022056 DSPG and CSPG translocate to the lysosome for degradation IEA Gallus gallus A0A1D5P8Z1 R-GGA-2022061 https://reactome.org/PathwayBrowser/#/R-GGA-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Gallus gallus A0A1D5P8Z1 R-GGA-2022063 https://reactome.org/PathwayBrowser/#/R-GGA-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Gallus gallus A0A1D5P8Z1 R-GGA-2022065 https://reactome.org/PathwayBrowser/#/R-GGA-2022065 DSPGs are secreted IEA Gallus gallus A0A1D5P8Z1 R-GGA-2022911 https://reactome.org/PathwayBrowser/#/R-GGA-2022911 CSPG is secreted IEA Gallus gallus A0A1D5P8Z1 R-GGA-9632033 https://reactome.org/PathwayBrowser/#/R-GGA-9632033 CHSY1 transfers GalNAc to chondroitin IEA Gallus gallus A0A1D5P8Z1 R-GGA-9632034 https://reactome.org/PathwayBrowser/#/R-GGA-9632034 CHSY1 transfers GlcA to chondroitin IEA Gallus gallus A0A1D5P8Z5 R-GGA-5173005 https://reactome.org/PathwayBrowser/#/R-GGA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Gallus gallus A0A1D5P8Z5 R-GGA-5173192 https://reactome.org/PathwayBrowser/#/R-GGA-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Gallus gallus A0A1D5P8Z8 R-GGA-419003 https://reactome.org/PathwayBrowser/#/R-GGA-419003 Interaction of Nectins with Afadin IEA Gallus gallus A0A1D5P903 R-GGA-400677 https://reactome.org/PathwayBrowser/#/R-GGA-400677 Rnd1 interacts with Plexin-B1:Sema4D IEA Gallus gallus A0A1D5P903 R-GGA-416559 https://reactome.org/PathwayBrowser/#/R-GGA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Gallus gallus A0A1D5P903 R-GGA-416562 https://reactome.org/PathwayBrowser/#/R-GGA-416562 p190RhoGAP binds Plexin-B1 IEA Gallus gallus A0A1D5P903 R-GGA-416588 https://reactome.org/PathwayBrowser/#/R-GGA-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Gallus gallus A0A1D5P903 R-GGA-416594 https://reactome.org/PathwayBrowser/#/R-GGA-416594 LARG and PDZ-RhoGEF binds to Plexin-B1 IEA Gallus gallus A0A1D5P903 R-GGA-9696271 https://reactome.org/PathwayBrowser/#/R-GGA-9696271 RND1 binds effectors IEA Gallus gallus A0A1D5P903 R-GGA-9696274 https://reactome.org/PathwayBrowser/#/R-GGA-9696274 RND1 binds GTP IEA Gallus gallus A0A1D5P908 R-GGA-1678923 https://reactome.org/PathwayBrowser/#/R-GGA-1678923 TLR folding by chaperones GP96 and CNPY3 IEA Gallus gallus A0A1D5P908 R-GGA-1678944 https://reactome.org/PathwayBrowser/#/R-GGA-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex IEA Gallus gallus A0A1D5P927 R-GGA-606287 https://reactome.org/PathwayBrowser/#/R-GGA-606287 RSF complex binds the centromere IEA Gallus gallus A0A1D5P939 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5P939 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5P943 R-GGA-2064406 https://reactome.org/PathwayBrowser/#/R-GGA-2064406 Translocation of YAP1:ZO-2 (TJP2) to the nucleus IEA Gallus gallus A0A1D5P943 R-GGA-2064418 https://reactome.org/PathwayBrowser/#/R-GGA-2064418 WWTR1 (TAZ) binds ZO-2 (TJP2) IEA Gallus gallus A0A1D5P943 R-GGA-2064421 https://reactome.org/PathwayBrowser/#/R-GGA-2064421 YAP1 binds ZO-2 (TJP2) IEA Gallus gallus A0A1D5P943 R-GGA-351871 https://reactome.org/PathwayBrowser/#/R-GGA-351871 Caspase-mediated cleavage of Z0-2 IEA Gallus gallus A0A1D5P943 R-GGA-9013009 https://reactome.org/PathwayBrowser/#/R-GGA-9013009 RHOA binds effectors at the plasma membrane IEA Gallus gallus A0A1D5P943 R-GGA-9013024 https://reactome.org/PathwayBrowser/#/R-GGA-9013024 RHOB binds effectors at the plasma membrane IEA Gallus gallus A0A1D5P943 R-GGA-9013110 https://reactome.org/PathwayBrowser/#/R-GGA-9013110 RHOC binds effectors at the plasma membrane IEA Gallus gallus A0A1D5P950 R-GGA-8943817 https://reactome.org/PathwayBrowser/#/R-GGA-8943817 MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter IEA Gallus gallus A0A1D5P954 R-GGA-72103 https://reactome.org/PathwayBrowser/#/R-GGA-72103 Formation of pre-mRNPs IEA Gallus gallus A0A1D5P954 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5P970 R-GGA-76590 https://reactome.org/PathwayBrowser/#/R-GGA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Gallus gallus A0A1D5P973 R-GGA-174587 https://reactome.org/PathwayBrowser/#/R-GGA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Gallus gallus A0A1D5P973 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus A0A1D5P973 R-GGA-203979 https://reactome.org/PathwayBrowser/#/R-GGA-203979 Coat Assembly IEA Gallus gallus A0A1D5P973 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus A0A1D5P973 R-GGA-5694417 https://reactome.org/PathwayBrowser/#/R-GGA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Gallus gallus A0A1D5P973 R-GGA-5694522 https://reactome.org/PathwayBrowser/#/R-GGA-5694522 Inner coat assembly and cargo binding IEA Gallus gallus A0A1D5P973 R-GGA-5694527 https://reactome.org/PathwayBrowser/#/R-GGA-5694527 Loss of SAR1B GTPase IEA Gallus gallus A0A1D5P973 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus A0A1D5P973 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus A0A1D5P973 R-GGA-983425 https://reactome.org/PathwayBrowser/#/R-GGA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Gallus gallus A0A1D5P974 R-GGA-9018785 https://reactome.org/PathwayBrowser/#/R-GGA-9018785 RHOBTB2 binds GTP IEA Gallus gallus A0A1D5P974 R-GGA-9018787 https://reactome.org/PathwayBrowser/#/R-GGA-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Gallus gallus A0A1D5P986 R-GGA-8980228 https://reactome.org/PathwayBrowser/#/R-GGA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Gallus gallus A0A1D5P9A2 R-GGA-8938217 https://reactome.org/PathwayBrowser/#/R-GGA-8938217 RUNX1 binds the SWI/SNF complex IEA Gallus gallus A0A1D5P9A5 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus A0A1D5P9A5 R-GGA-77591 https://reactome.org/PathwayBrowser/#/R-GGA-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Gallus gallus A0A1D5P9A5 R-GGA-77592 https://reactome.org/PathwayBrowser/#/R-GGA-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Gallus gallus A0A1D5P9A5 R-GGA-77593 https://reactome.org/PathwayBrowser/#/R-GGA-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Gallus gallus A0A1D5P9C1 R-GGA-5610723 https://reactome.org/PathwayBrowser/#/R-GGA-5610723 GLI proteins bind SUFU IEA Gallus gallus A0A1D5P9C1 R-GGA-5610737 https://reactome.org/PathwayBrowser/#/R-GGA-5610737 NUMB:ITCH bind and ubiquitnate GLI1 IEA Gallus gallus A0A1D5P9C1 R-GGA-5610742 https://reactome.org/PathwayBrowser/#/R-GGA-5610742 SCF(beta-TrCP) ubiquitinates p-GLI1 IEA Gallus gallus A0A1D5P9C1 R-GGA-5610758 https://reactome.org/PathwayBrowser/#/R-GGA-5610758 GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP IEA Gallus gallus A0A1D5P9C1 R-GGA-5610760 https://reactome.org/PathwayBrowser/#/R-GGA-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Gallus gallus A0A1D5P9C1 R-GGA-5610766 https://reactome.org/PathwayBrowser/#/R-GGA-5610766 The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base IEA Gallus gallus A0A1D5P9C1 R-GGA-5610767 https://reactome.org/PathwayBrowser/#/R-GGA-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Gallus gallus A0A1D5P9C1 R-GGA-5635843 https://reactome.org/PathwayBrowser/#/R-GGA-5635843 GLI translocates to the nucleus IEA Gallus gallus A0A1D5P9C1 R-GGA-5635845 https://reactome.org/PathwayBrowser/#/R-GGA-5635845 GLI proteins bind CDC73 IEA Gallus gallus A0A1D5P9C1 R-GGA-5635859 https://reactome.org/PathwayBrowser/#/R-GGA-5635859 GLI:SUFU dissociates IEA Gallus gallus A0A1D5P9C1 R-GGA-5635860 https://reactome.org/PathwayBrowser/#/R-GGA-5635860 GLI:SUFU translocates to the ciliary tip in response to Hh signaling IEA Gallus gallus A0A1D5P9C1 R-GGA-5635861 https://reactome.org/PathwayBrowser/#/R-GGA-5635861 NUMB:ITCH binds GLI1 IEA Gallus gallus A0A1D5P9C1 R-GGA-5635864 https://reactome.org/PathwayBrowser/#/R-GGA-5635864 NUMB:ITCH ubiquitinates GLI1 IEA Gallus gallus A0A1D5P9C1 R-GGA-5635868 https://reactome.org/PathwayBrowser/#/R-GGA-5635868 ub-GLI is degraded by the proteasome IEA Gallus gallus A0A1D5P9D0 R-GGA-2028555 https://reactome.org/PathwayBrowser/#/R-GGA-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Gallus gallus A0A1D5P9D0 R-GGA-2028583 https://reactome.org/PathwayBrowser/#/R-GGA-2028583 Phosphorylation of YAP by LATS2 IEA Gallus gallus A0A1D5P9D0 R-GGA-2028589 https://reactome.org/PathwayBrowser/#/R-GGA-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Gallus gallus A0A1D5P9D0 R-GGA-2028598 https://reactome.org/PathwayBrowser/#/R-GGA-2028598 Phosphorylation of YAP by LATS1 IEA Gallus gallus A0A1D5P9D0 R-GGA-2028626 https://reactome.org/PathwayBrowser/#/R-GGA-2028626 Phosphorylated MOB1A proteins associate with LATS proteins IEA Gallus gallus A0A1D5P9D0 R-GGA-2028629 https://reactome.org/PathwayBrowser/#/R-GGA-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Gallus gallus A0A1D5P9D0 R-GGA-2028635 https://reactome.org/PathwayBrowser/#/R-GGA-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Gallus gallus A0A1D5P9D0 R-GGA-2028661 https://reactome.org/PathwayBrowser/#/R-GGA-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Gallus gallus A0A1D5P9D0 R-GGA-2028670 https://reactome.org/PathwayBrowser/#/R-GGA-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Gallus gallus A0A1D5P9D0 R-GGA-2028673 https://reactome.org/PathwayBrowser/#/R-GGA-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Gallus gallus A0A1D5P9D0 R-GGA-2028675 https://reactome.org/PathwayBrowser/#/R-GGA-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Gallus gallus A0A1D5P9D0 R-GGA-2028679 https://reactome.org/PathwayBrowser/#/R-GGA-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Gallus gallus A0A1D5P9D0 R-GGA-2060328 https://reactome.org/PathwayBrowser/#/R-GGA-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Gallus gallus A0A1D5P9D7 R-GGA-8938217 https://reactome.org/PathwayBrowser/#/R-GGA-8938217 RUNX1 binds the SWI/SNF complex IEA Gallus gallus A0A1D5P9D7 R-GGA-9932448 https://reactome.org/PathwayBrowser/#/R-GGA-9932448 SMARCC binds SMARCD IEA Gallus gallus A0A1D5P9D7 R-GGA-9932449 https://reactome.org/PathwayBrowser/#/R-GGA-9932449 SMARCE1 and SMARCB1 bind SMARCC dimer:SMARCDs IEA Gallus gallus A0A1D5P9D7 R-GGA-9932832 https://reactome.org/PathwayBrowser/#/R-GGA-9932832 BRD7 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2 IEA Gallus gallus A0A1D5P9D7 R-GGA-9932843 https://reactome.org/PathwayBrowser/#/R-GGA-9932843 PHF10 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD7 IEA Gallus gallus A0A1D5P9D7 R-GGA-9933236 https://reactome.org/PathwayBrowser/#/R-GGA-9933236 SS18-containing ATPase complex binds SMARCC dimer:SMARCDs:BICRAs:BRD9 IEA Gallus gallus A0A1D5P9D7 R-GGA-9933237 https://reactome.org/PathwayBrowser/#/R-GGA-9933237 PBRM1-containing ATPase complex binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD&:PHF10 IEA Gallus gallus A0A1D5P9D7 R-GGA-9934021 https://reactome.org/PathwayBrowser/#/R-GGA-9934021 Formation of neuronal progenitor BAF (npBAF) IEA Gallus gallus A0A1D5P9D7 R-GGA-9934022 https://reactome.org/PathwayBrowser/#/R-GGA-9934022 DPF2, PHF10 bind SMARCC1:SMARCC2 dimer:SMARD1:ARID1A IEA Gallus gallus A0A1D5P9D7 R-GGA-9934024 https://reactome.org/PathwayBrowser/#/R-GGA-9934024 SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10 IEA Gallus gallus A0A1D5P9D7 R-GGA-9934026 https://reactome.org/PathwayBrowser/#/R-GGA-9934026 SMARCE1 and SMARCB1 bind SMARCC1:SMARCC2 dimer:SMARCD1 IEA Gallus gallus A0A1D5P9D7 R-GGA-9934027 https://reactome.org/PathwayBrowser/#/R-GGA-9934027 SMARCC1 and SMARCC2 bind SMARCD1 IEA Gallus gallus A0A1D5P9D9 R-GGA-8875318 https://reactome.org/PathwayBrowser/#/R-GGA-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Gallus gallus A0A1D5P9D9 R-GGA-8875320 https://reactome.org/PathwayBrowser/#/R-GGA-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Gallus gallus A0A1D5P9D9 R-GGA-8876188 https://reactome.org/PathwayBrowser/#/R-GGA-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Gallus gallus A0A1D5P9D9 R-GGA-8876190 https://reactome.org/PathwayBrowser/#/R-GGA-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Gallus gallus A0A1D5P9D9 R-GGA-8876191 https://reactome.org/PathwayBrowser/#/R-GGA-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Gallus gallus A0A1D5P9D9 R-GGA-8876193 https://reactome.org/PathwayBrowser/#/R-GGA-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Gallus gallus A0A1D5P9D9 R-GGA-8876454 https://reactome.org/PathwayBrowser/#/R-GGA-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Gallus gallus A0A1D5P9D9 R-GGA-8876616 https://reactome.org/PathwayBrowser/#/R-GGA-8876616 DENND6A,B exchange GTP for GDP on RAB14 IEA Gallus gallus A0A1D5P9D9 R-GGA-8876837 https://reactome.org/PathwayBrowser/#/R-GGA-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Gallus gallus A0A1D5P9D9 R-GGA-8877308 https://reactome.org/PathwayBrowser/#/R-GGA-8877308 MADD exchanges GTP for GDP on RAB27 IEA Gallus gallus A0A1D5P9D9 R-GGA-8877311 https://reactome.org/PathwayBrowser/#/R-GGA-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 IEA Gallus gallus A0A1D5P9D9 R-GGA-8877451 https://reactome.org/PathwayBrowser/#/R-GGA-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Gallus gallus A0A1D5P9D9 R-GGA-8877612 https://reactome.org/PathwayBrowser/#/R-GGA-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Gallus gallus A0A1D5P9D9 R-GGA-8877760 https://reactome.org/PathwayBrowser/#/R-GGA-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Gallus gallus A0A1D5P9D9 R-GGA-8877813 https://reactome.org/PathwayBrowser/#/R-GGA-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Gallus gallus A0A1D5P9D9 R-GGA-8877998 https://reactome.org/PathwayBrowser/#/R-GGA-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Gallus gallus A0A1D5P9E1 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5P9E1 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5P9E1 R-GGA-8952044 https://reactome.org/PathwayBrowser/#/R-GGA-8952044 AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P9E1 R-GGA-8952618 https://reactome.org/PathwayBrowser/#/R-GGA-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P9E1 R-GGA-8952620 https://reactome.org/PathwayBrowser/#/R-GGA-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P9E1 R-GGA-8952626 https://reactome.org/PathwayBrowser/#/R-GGA-8952626 AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P9E1 R-GGA-8952630 https://reactome.org/PathwayBrowser/#/R-GGA-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P9E1 R-GGA-8952631 https://reactome.org/PathwayBrowser/#/R-GGA-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P9E1 R-GGA-8952638 https://reactome.org/PathwayBrowser/#/R-GGA-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P9E1 R-GGA-8952639 https://reactome.org/PathwayBrowser/#/R-GGA-8952639 NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P9E1 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5P9E1 R-GGA-8956045 https://reactome.org/PathwayBrowser/#/R-GGA-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P9E1 R-GGA-8956099 https://reactome.org/PathwayBrowser/#/R-GGA-8956099 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 IEA Gallus gallus A0A1D5P9E1 R-GGA-8956103 https://reactome.org/PathwayBrowser/#/R-GGA-8956103 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha IEA Gallus gallus A0A1D5P9E1 R-GGA-8956106 https://reactome.org/PathwayBrowser/#/R-GGA-8956106 VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha IEA Gallus gallus A0A1D5P9E1 R-GGA-8956200 https://reactome.org/PathwayBrowser/#/R-GGA-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5P9E1 R-GGA-9755303 https://reactome.org/PathwayBrowser/#/R-GGA-9755303 26S proteasome degrades HIFalpha IEA Gallus gallus A0A1D5P9E6 R-GGA-4641342 https://reactome.org/PathwayBrowser/#/R-GGA-4641342 SUMOylation of TOP2A with SUMO1 IEA Gallus gallus A0A1D5P9E6 R-GGA-4641350 https://reactome.org/PathwayBrowser/#/R-GGA-4641350 PIAS4 SUMOylates TOP2A with SUMO2,3 IEA Gallus gallus A0A1D5P9F2 R-GGA-5696997 https://reactome.org/PathwayBrowser/#/R-GGA-5696997 USP24 deubiquitinates DDB2 IEA Gallus gallus A0A1D5P9F3 R-GGA-8851018 https://reactome.org/PathwayBrowser/#/R-GGA-8851018 BTN2A1 binds DC-SIGN IEA Gallus gallus A0A1D5P9F3 R-GGA-8851038 https://reactome.org/PathwayBrowser/#/R-GGA-8851038 BTN3A1 binds prenylated phosphoantigens IEA Gallus gallus A0A1D5P9F3 R-GGA-8851044 https://reactome.org/PathwayBrowser/#/R-GGA-8851044 BTN1A1 binds xanthine oxidoreductase (XDH) IEA Gallus gallus A0A1D5P9F3 R-GGA-8851979 https://reactome.org/PathwayBrowser/#/R-GGA-8851979 BTNL9 binds immune cell surfaces IEA Gallus gallus A0A1D5P9F3 R-GGA-8851988 https://reactome.org/PathwayBrowser/#/R-GGA-8851988 BTN2A2 binds T cell surface IEA Gallus gallus A0A1D5P9F3 R-GGA-8852010 https://reactome.org/PathwayBrowser/#/R-GGA-8852010 BTNL2 binds activated T cells surface IEA Gallus gallus A0A1D5P9F3 R-GGA-8938431 https://reactome.org/PathwayBrowser/#/R-GGA-8938431 BTN3A1 and BTN1A1 binds periplakin (PPL) IEA Gallus gallus A0A1D5P9F9 R-GGA-1006143 https://reactome.org/PathwayBrowser/#/R-GGA-1006143 CD46 binds C3b IEA Gallus gallus A0A1D5P9F9 R-GGA-166817 https://reactome.org/PathwayBrowser/#/R-GGA-166817 Cleavage of C3 by C3 convertases IEA Gallus gallus A0A1D5P9F9 R-GGA-173636 https://reactome.org/PathwayBrowser/#/R-GGA-173636 Formation of classic pathway C5 convertase IEA Gallus gallus A0A1D5P9F9 R-GGA-173680 https://reactome.org/PathwayBrowser/#/R-GGA-173680 Activation of C5 IEA Gallus gallus A0A1D5P9F9 R-GGA-173739 https://reactome.org/PathwayBrowser/#/R-GGA-173739 Spontaneous hydrolysis of C3 thioester IEA Gallus gallus A0A1D5P9F9 R-GGA-173740 https://reactome.org/PathwayBrowser/#/R-GGA-173740 Factor B binds to C3(H2O) IEA Gallus gallus A0A1D5P9F9 R-GGA-173745 https://reactome.org/PathwayBrowser/#/R-GGA-173745 Factor D cleaves C3(H2O)-bound Factor B IEA Gallus gallus A0A1D5P9F9 R-GGA-183122 https://reactome.org/PathwayBrowser/#/R-GGA-183122 Factor D cleaves C3b-bound Factor B IEA Gallus gallus A0A1D5P9F9 R-GGA-183126 https://reactome.org/PathwayBrowser/#/R-GGA-183126 Factor B binds to surface-associated C3b IEA Gallus gallus A0A1D5P9F9 R-GGA-183130 https://reactome.org/PathwayBrowser/#/R-GGA-183130 C3(H2O):Factor Bb cleaves C3 to C3b and C3a IEA Gallus gallus A0A1D5P9F9 R-GGA-3266557 https://reactome.org/PathwayBrowser/#/R-GGA-3266557 Factor I cleaves iC3b IEA Gallus gallus A0A1D5P9F9 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5P9F9 R-GGA-444647 https://reactome.org/PathwayBrowser/#/R-GGA-444647 C3a receptor binds anaphylatoxin C3a IEA Gallus gallus A0A1D5P9F9 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5P9F9 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5P9F9 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5P9F9 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5P9F9 R-GGA-8851436 https://reactome.org/PathwayBrowser/#/R-GGA-8851436 CFHR dimers bind C3b IEA Gallus gallus A0A1D5P9F9 R-GGA-8852809 https://reactome.org/PathwayBrowser/#/R-GGA-8852809 CPN, CPB2 cleave C3a, C5a IEA Gallus gallus A0A1D5P9F9 R-GGA-8852874 https://reactome.org/PathwayBrowser/#/R-GGA-8852874 CR2 binds C3d, C3dg, iC3b IEA Gallus gallus A0A1D5P9F9 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5P9F9 R-GGA-964811 https://reactome.org/PathwayBrowser/#/R-GGA-964811 C5AR2 binds anaphylatoxins and thier desArginated derivatives IEA Gallus gallus A0A1D5P9F9 R-GGA-976743 https://reactome.org/PathwayBrowser/#/R-GGA-976743 Factor I inactivates plasma Factor H-bound C3b IEA Gallus gallus A0A1D5P9F9 R-GGA-976768 https://reactome.org/PathwayBrowser/#/R-GGA-976768 Factor H binds to C3b IEA Gallus gallus A0A1D5P9F9 R-GGA-976810 https://reactome.org/PathwayBrowser/#/R-GGA-976810 Complement factor I binds to extracellular Factor H:C3b IEA Gallus gallus A0A1D5P9F9 R-GGA-977359 https://reactome.org/PathwayBrowser/#/R-GGA-977359 Complement factor I binds to membrane-associated Factor H:C3b IEA Gallus gallus A0A1D5P9F9 R-GGA-977363 https://reactome.org/PathwayBrowser/#/R-GGA-977363 Factor H binds to C3bBb IEA Gallus gallus A0A1D5P9F9 R-GGA-977371 https://reactome.org/PathwayBrowser/#/R-GGA-977371 Factor I inactivates Factor H-boundC3b IEA Gallus gallus A0A1D5P9F9 R-GGA-977375 https://reactome.org/PathwayBrowser/#/R-GGA-977375 CR1 binds C3bBb/C4bC2a IEA Gallus gallus A0A1D5P9F9 R-GGA-977602 https://reactome.org/PathwayBrowser/#/R-GGA-977602 Complement factor I binds to MCP, CR1:C4b, C3b IEA Gallus gallus A0A1D5P9F9 R-GGA-977605 https://reactome.org/PathwayBrowser/#/R-GGA-977605 Factor H displaces Bb IEA Gallus gallus A0A1D5P9F9 R-GGA-977615 https://reactome.org/PathwayBrowser/#/R-GGA-977615 Factor I inactivates MCP/CR1-bound C4b/C3b IEA Gallus gallus A0A1D5P9F9 R-GGA-977619 https://reactome.org/PathwayBrowser/#/R-GGA-977619 CD55 (DAF) promotes C3bBb/C4bC2a dissociation IEA Gallus gallus A0A1D5P9F9 R-GGA-977629 https://reactome.org/PathwayBrowser/#/R-GGA-977629 Displacement of C2a/Bb by CR1 IEA Gallus gallus A0A1D5P9F9 R-GGA-981535 https://reactome.org/PathwayBrowser/#/R-GGA-981535 CD55 (DAF) binds C3bBb, C4bC2a IEA Gallus gallus A0A1D5P9F9 R-GGA-981539 https://reactome.org/PathwayBrowser/#/R-GGA-981539 C3b binds to cell surface IEA Gallus gallus A0A1D5P9F9 R-GGA-981728 https://reactome.org/PathwayBrowser/#/R-GGA-981728 Factor H binds to membrane-associated C3b IEA Gallus gallus A0A1D5P9G1 R-GGA-388828 https://reactome.org/PathwayBrowser/#/R-GGA-388828 PD-1 binds B7DC and B7H1 IEA Gallus gallus A0A1D5P9G1 R-GGA-389758 https://reactome.org/PathwayBrowser/#/R-GGA-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Gallus gallus A0A1D5P9G1 R-GGA-389759 https://reactome.org/PathwayBrowser/#/R-GGA-389759 Interaction of SHP-1 or SHP-2 with phospho PD-1 IEA Gallus gallus A0A1D5P9G1 R-GGA-389762 https://reactome.org/PathwayBrowser/#/R-GGA-389762 Phosphorylation of PD-1 IEA Gallus gallus A0A1D5P9H1 R-GGA-5624949 https://reactome.org/PathwayBrowser/#/R-GGA-5624949 Assembly of the anterograde IFT train IEA Gallus gallus A0A1D5P9H1 R-GGA-5625416 https://reactome.org/PathwayBrowser/#/R-GGA-5625416 Anterograde IFT IEA Gallus gallus A0A1D5P9H1 R-GGA-5625426 https://reactome.org/PathwayBrowser/#/R-GGA-5625426 Retrograde IFT IEA Gallus gallus A0A1D5P9H3 R-GGA-8949178 https://reactome.org/PathwayBrowser/#/R-GGA-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix IEA Gallus gallus A0A1D5P9H3 R-GGA-8953461 https://reactome.org/PathwayBrowser/#/R-GGA-8953461 SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex IEA Gallus gallus A0A1D5P9H5 R-GGA-6781764 https://reactome.org/PathwayBrowser/#/R-GGA-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Gallus gallus A0A1D5P9H8 R-GGA-1482539 https://reactome.org/PathwayBrowser/#/R-GGA-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Gallus gallus A0A1D5P9H8 R-GGA-1482635 https://reactome.org/PathwayBrowser/#/R-GGA-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Gallus gallus A0A1D5P9J0 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus A0A1D5P9J0 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus A0A1D5P9J0 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus A0A1D5P9J0 R-GGA-1981120 https://reactome.org/PathwayBrowser/#/R-GGA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Gallus gallus A0A1D5P9J0 R-GGA-2002460 https://reactome.org/PathwayBrowser/#/R-GGA-2002460 P4HB binds Collagen chains IEA Gallus gallus A0A1D5P9J0 R-GGA-2089971 https://reactome.org/PathwayBrowser/#/R-GGA-2089971 Secretion of collagens IEA Gallus gallus A0A1D5P9J0 R-GGA-2168038 https://reactome.org/PathwayBrowser/#/R-GGA-2168038 Collagen type XV restin release IEA Gallus gallus A0A1D5P9J0 R-GGA-8944216 https://reactome.org/PathwayBrowser/#/R-GGA-8944216 Association of procollagen type XV IEA Gallus gallus A0A1D5P9J0 R-GGA-8948228 https://reactome.org/PathwayBrowser/#/R-GGA-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Gallus gallus A0A1D5P9J0 R-GGA-8948231 https://reactome.org/PathwayBrowser/#/R-GGA-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Gallus gallus A0A1D5P9J0 R-GGA-8948232 https://reactome.org/PathwayBrowser/#/R-GGA-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Gallus gallus A0A1D5P9J0 R-GGA-8948234 https://reactome.org/PathwayBrowser/#/R-GGA-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Gallus gallus A0A1D5P9K2 R-GGA-1168640 https://reactome.org/PathwayBrowser/#/R-GGA-1168640 Ubiquitinated IkB is degraded IEA Gallus gallus A0A1D5P9K2 R-GGA-1234159 https://reactome.org/PathwayBrowser/#/R-GGA-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Gallus gallus A0A1D5P9K2 R-GGA-1236970 https://reactome.org/PathwayBrowser/#/R-GGA-1236970 Proteasomal clevage of exogenous antigen (26S proteasome catalyst) IEA Gallus gallus A0A1D5P9K2 R-GGA-1504193 https://reactome.org/PathwayBrowser/#/R-GGA-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-174058 https://reactome.org/PathwayBrowser/#/R-GGA-174058 Degradation of multiubiquitinated Cdh1 IEA Gallus gallus A0A1D5P9K2 R-GGA-174105 https://reactome.org/PathwayBrowser/#/R-GGA-174105 Degradation of multiubiquitinated cell cycle proteins IEA Gallus gallus A0A1D5P9K2 R-GGA-174202 https://reactome.org/PathwayBrowser/#/R-GGA-174202 Degradation of multiubiquitinated Securin IEA Gallus gallus A0A1D5P9K2 R-GGA-174255 https://reactome.org/PathwayBrowser/#/R-GGA-174255 Degradation multiubiquitinated Cyclin A IEA Gallus gallus A0A1D5P9K2 R-GGA-187574 https://reactome.org/PathwayBrowser/#/R-GGA-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-188191 https://reactome.org/PathwayBrowser/#/R-GGA-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Gallus gallus A0A1D5P9K2 R-GGA-209061 https://reactome.org/PathwayBrowser/#/R-GGA-209061 Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex IEA Gallus gallus A0A1D5P9K2 R-GGA-2130282 https://reactome.org/PathwayBrowser/#/R-GGA-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-264458 https://reactome.org/PathwayBrowser/#/R-GGA-264458 Proteasome mediated degradation of COP1 IEA Gallus gallus A0A1D5P9K2 R-GGA-353125 https://reactome.org/PathwayBrowser/#/R-GGA-353125 26S proteosome degrades ODC holoenzyme complex IEA Gallus gallus A0A1D5P9K2 R-GGA-3640874 https://reactome.org/PathwayBrowser/#/R-GGA-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-450466 https://reactome.org/PathwayBrowser/#/R-GGA-450466 AUF1:mRNA complex is destroyed IEA Gallus gallus A0A1D5P9K2 R-GGA-4608855 https://reactome.org/PathwayBrowser/#/R-GGA-4608855 PRICKLE1 is degraded by the proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-4641256 https://reactome.org/PathwayBrowser/#/R-GGA-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-5362448 https://reactome.org/PathwayBrowser/#/R-GGA-5362448 Hh C-terminal fragments are degraded by the proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-5607724 https://reactome.org/PathwayBrowser/#/R-GGA-5607724 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex IEA Gallus gallus A0A1D5P9K2 R-GGA-5610754 https://reactome.org/PathwayBrowser/#/R-GGA-5610754 GLI3 is partially degraded by the proteasome to yield the GLI3 repressor IEA Gallus gallus A0A1D5P9K2 R-GGA-5610758 https://reactome.org/PathwayBrowser/#/R-GGA-5610758 GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP IEA Gallus gallus A0A1D5P9K2 R-GGA-5610760 https://reactome.org/PathwayBrowser/#/R-GGA-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Gallus gallus A0A1D5P9K2 R-GGA-5635854 https://reactome.org/PathwayBrowser/#/R-GGA-5635854 GLI2,3 are degraded by the proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-5635868 https://reactome.org/PathwayBrowser/#/R-GGA-5635868 ub-GLI is degraded by the proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-5658430 https://reactome.org/PathwayBrowser/#/R-GGA-5658430 NF1 is degraded by the proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-5665854 https://reactome.org/PathwayBrowser/#/R-GGA-5665854 ADRM1:26S proteaseome binds UCHL5 IEA Gallus gallus A0A1D5P9K2 R-GGA-5665871 https://reactome.org/PathwayBrowser/#/R-GGA-5665871 ADRM1 binds 26S proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-5668481 https://reactome.org/PathwayBrowser/#/R-GGA-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Gallus gallus A0A1D5P9K2 R-GGA-5668520 https://reactome.org/PathwayBrowser/#/R-GGA-5668520 26Sproteasome degrades K48polyUb-NIK IEA Gallus gallus A0A1D5P9K2 R-GGA-5687112 https://reactome.org/PathwayBrowser/#/R-GGA-5687112 MAPK6 is degraded by the 26S proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-5689539 https://reactome.org/PathwayBrowser/#/R-GGA-5689539 ADRM1:26S proteaseome binds USP14 IEA Gallus gallus A0A1D5P9K2 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5P9K2 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5P9K2 R-GGA-68825 https://reactome.org/PathwayBrowser/#/R-GGA-68825 Ubiquitinated geminin is degraded by the proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-68948 https://reactome.org/PathwayBrowser/#/R-GGA-68948 Ubiquitinated Orc1 is degraded by the proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-69016 https://reactome.org/PathwayBrowser/#/R-GGA-69016 Ubiquitinated Cdc6 is degraded by the proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-69600 https://reactome.org/PathwayBrowser/#/R-GGA-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Gallus gallus A0A1D5P9K2 R-GGA-75825 https://reactome.org/PathwayBrowser/#/R-GGA-75825 Proteasome mediated degradation of Cyclin D1 IEA Gallus gallus A0A1D5P9K2 R-GGA-8850992 https://reactome.org/PathwayBrowser/#/R-GGA-8850992 Proteasome degrades polyubiquitinated PTEN IEA Gallus gallus A0A1D5P9K2 R-GGA-8854044 https://reactome.org/PathwayBrowser/#/R-GGA-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Gallus gallus A0A1D5P9K2 R-GGA-8854071 https://reactome.org/PathwayBrowser/#/R-GGA-8854071 Proteasome-mediated degradation of PolyUb-FBXL7 IEA Gallus gallus A0A1D5P9K2 R-GGA-8866553 https://reactome.org/PathwayBrowser/#/R-GGA-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-8932355 https://reactome.org/PathwayBrowser/#/R-GGA-8932355 26S proteasome degrades Ub-NFE2L2 IEA Gallus gallus A0A1D5P9K2 R-GGA-8939801 https://reactome.org/PathwayBrowser/#/R-GGA-8939801 26S proteasome degrades PolyUb-RUNX2 IEA Gallus gallus A0A1D5P9K2 R-GGA-8952408 https://reactome.org/PathwayBrowser/#/R-GGA-8952408 Polyubiquitinated RUNX3 is degraded by the proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-8956140 https://reactome.org/PathwayBrowser/#/R-GGA-8956140 NEDD8 and UBD bind NUB1 and the 26S proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-8956184 https://reactome.org/PathwayBrowser/#/R-GGA-8956184 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates IEA Gallus gallus A0A1D5P9K2 R-GGA-8957265 https://reactome.org/PathwayBrowser/#/R-GGA-8957265 26S proteasome degrades TP73 polyubiquitinated by ITCH IEA Gallus gallus A0A1D5P9K2 R-GGA-9755303 https://reactome.org/PathwayBrowser/#/R-GGA-9755303 26S proteasome degrades HIFalpha IEA Gallus gallus A0A1D5P9K2 R-GGA-9755306 https://reactome.org/PathwayBrowser/#/R-GGA-9755306 ub UBXN7 is degraded by the 26S proteasome IEA Gallus gallus A0A1D5P9K2 R-GGA-9762096 https://reactome.org/PathwayBrowser/#/R-GGA-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Gallus gallus A0A1D5P9K2 R-GGA-983150 https://reactome.org/PathwayBrowser/#/R-GGA-983150 Proteasomal cleavage of substrate IEA Gallus gallus A0A1D5P9K2 R-GGA-9908026 https://reactome.org/PathwayBrowser/#/R-GGA-9908026 Formation of the 19S regulatory particle precursor IEA Gallus gallus A0A1D5P9K2 R-GGA-9934893 https://reactome.org/PathwayBrowser/#/R-GGA-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 IEA Gallus gallus A0A1D5P9L5 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus A0A1D5P9L5 R-GGA-77590 https://reactome.org/PathwayBrowser/#/R-GGA-77590 Recruitment of CstF to the CPSF Bound Pre-mRNA IEA Gallus gallus A0A1D5P9L5 R-GGA-77591 https://reactome.org/PathwayBrowser/#/R-GGA-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Gallus gallus A0A1D5P9L5 R-GGA-77592 https://reactome.org/PathwayBrowser/#/R-GGA-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Gallus gallus A0A1D5P9L5 R-GGA-77593 https://reactome.org/PathwayBrowser/#/R-GGA-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Gallus gallus A0A1D5P9L6 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5P9L6 R-GGA-6799350 https://reactome.org/PathwayBrowser/#/R-GGA-6799350 Exocytosis of specific granule membrane proteins IEA Gallus gallus A0A1D5P9M1 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5P9Q8 R-GGA-1889955 https://reactome.org/PathwayBrowser/#/R-GGA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Gallus gallus A0A1D5P9U3 R-GGA-191323 https://reactome.org/PathwayBrowser/#/R-GGA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Gallus gallus A0A1D5P9U9 R-GGA-507868 https://reactome.org/PathwayBrowser/#/R-GGA-507868 Aquaporins passively transport water into cells IEA Gallus gallus A0A1D5P9U9 R-GGA-507870 https://reactome.org/PathwayBrowser/#/R-GGA-507870 Aquaporins passively transport water out of cells IEA Gallus gallus A0A1D5P9V5 R-GGA-426155 https://reactome.org/PathwayBrowser/#/R-GGA-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Gallus gallus A0A1D5P9V6 R-GGA-5696080 https://reactome.org/PathwayBrowser/#/R-GGA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Gallus gallus A0A1D5P9V6 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5P9V6 R-GGA-6799350 https://reactome.org/PathwayBrowser/#/R-GGA-6799350 Exocytosis of specific granule membrane proteins IEA Gallus gallus A0A1D5P9V6 R-GGA-6808464 https://reactome.org/PathwayBrowser/#/R-GGA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Gallus gallus A0A1D5P9X0 R-GGA-3928578 https://reactome.org/PathwayBrowser/#/R-GGA-3928578 EPH receptors autophosphorylate IEA Gallus gallus A0A1D5P9X0 R-GGA-3928591 https://reactome.org/PathwayBrowser/#/R-GGA-3928591 EPH:EFN tetramers oligomerise IEA Gallus gallus A0A1D5P9X0 R-GGA-3928592 https://reactome.org/PathwayBrowser/#/R-GGA-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Gallus gallus A0A1D5P9X0 R-GGA-3928595 https://reactome.org/PathwayBrowser/#/R-GGA-3928595 N-WASP binds ARP2/3 and G-actin IEA Gallus gallus A0A1D5P9X0 R-GGA-3928597 https://reactome.org/PathwayBrowser/#/R-GGA-3928597 EPH:EFN dimers tetramerise IEA Gallus gallus A0A1D5P9X0 R-GGA-3928598 https://reactome.org/PathwayBrowser/#/R-GGA-3928598 Recruitment of p190RhoGEF to p-FAK IEA Gallus gallus A0A1D5P9X0 R-GGA-3928601 https://reactome.org/PathwayBrowser/#/R-GGA-3928601 CDC42 and PIP2 bind WASL, activating it IEA Gallus gallus A0A1D5P9X0 R-GGA-3928604 https://reactome.org/PathwayBrowser/#/R-GGA-3928604 SFKs phosphorylate VAV2,3 IEA Gallus gallus A0A1D5P9X0 R-GGA-3928607 https://reactome.org/PathwayBrowser/#/R-GGA-3928607 p-EPHs bind VAV2,3 IEA Gallus gallus A0A1D5P9X0 R-GGA-3928612 https://reactome.org/PathwayBrowser/#/R-GGA-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5P9X0 R-GGA-3928614 https://reactome.org/PathwayBrowser/#/R-GGA-3928614 EFNB:GRB4 binds GIT1 IEA Gallus gallus A0A1D5P9X0 R-GGA-3928615 https://reactome.org/PathwayBrowser/#/R-GGA-3928615 EFNBs bind SFKs IEA Gallus gallus A0A1D5P9X0 R-GGA-3928617 https://reactome.org/PathwayBrowser/#/R-GGA-3928617 EPHB2 binds KALRN IEA Gallus gallus A0A1D5P9X0 R-GGA-3928624 https://reactome.org/PathwayBrowser/#/R-GGA-3928624 EPHBs bind EFNBs IEA Gallus gallus A0A1D5P9X0 R-GGA-3928625 https://reactome.org/PathwayBrowser/#/R-GGA-3928625 PAKs autophosphorylate IEA Gallus gallus A0A1D5P9X0 R-GGA-3928627 https://reactome.org/PathwayBrowser/#/R-GGA-3928627 EPHB phosphorylates TIAM1 IEA Gallus gallus A0A1D5P9X0 R-GGA-3928628 https://reactome.org/PathwayBrowser/#/R-GGA-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5P9X0 R-GGA-3928631 https://reactome.org/PathwayBrowser/#/R-GGA-3928631 GIT1 binds bPIX IEA Gallus gallus A0A1D5P9X0 R-GGA-3928633 https://reactome.org/PathwayBrowser/#/R-GGA-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Gallus gallus A0A1D5P9X0 R-GGA-3928639 https://reactome.org/PathwayBrowser/#/R-GGA-3928639 p-EFNB binds GRB4 IEA Gallus gallus A0A1D5P9X0 R-GGA-3928640 https://reactome.org/PathwayBrowser/#/R-GGA-3928640 PAKs phosphorylate MLC IEA Gallus gallus A0A1D5P9X0 R-GGA-3928641 https://reactome.org/PathwayBrowser/#/R-GGA-3928641 PAK binds RAC and bPIX IEA Gallus gallus A0A1D5P9X0 R-GGA-3928645 https://reactome.org/PathwayBrowser/#/R-GGA-3928645 EPHB:NMDAR binds TIAM1 IEA Gallus gallus A0A1D5P9X0 R-GGA-3928654 https://reactome.org/PathwayBrowser/#/R-GGA-3928654 Clathrin internalises EPH:EFN complexes IEA Gallus gallus A0A1D5P9X0 R-GGA-3928657 https://reactome.org/PathwayBrowser/#/R-GGA-3928657 MMP2,9 cleave EPHB IEA Gallus gallus A0A1D5P9X0 R-GGA-4093329 https://reactome.org/PathwayBrowser/#/R-GGA-4093329 EFNBs bind SDCBP IEA Gallus gallus A0A1D5P9X0 R-GGA-4093331 https://reactome.org/PathwayBrowser/#/R-GGA-4093331 Ras:GTP binds p120-RasGAP IEA Gallus gallus A0A1D5P9X0 R-GGA-4093332 https://reactome.org/PathwayBrowser/#/R-GGA-4093332 p-EPHB phosphorylates SDC2 IEA Gallus gallus A0A1D5P9X0 R-GGA-4093336 https://reactome.org/PathwayBrowser/#/R-GGA-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5P9X0 R-GGA-4093339 https://reactome.org/PathwayBrowser/#/R-GGA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Gallus gallus A0A1D5P9X9 R-GGA-5620921 https://reactome.org/PathwayBrowser/#/R-GGA-5620921 ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex IEA Gallus gallus A0A1D5P9X9 R-GGA-5623513 https://reactome.org/PathwayBrowser/#/R-GGA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Gallus gallus A0A1D5P9X9 R-GGA-5623519 https://reactome.org/PathwayBrowser/#/R-GGA-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Gallus gallus A0A1D5P9X9 R-GGA-5623521 https://reactome.org/PathwayBrowser/#/R-GGA-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5P9X9 R-GGA-5623524 https://reactome.org/PathwayBrowser/#/R-GGA-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Gallus gallus A0A1D5P9X9 R-GGA-5623525 https://reactome.org/PathwayBrowser/#/R-GGA-5623525 Cargo-carrying vesicles bud from the TGN IEA Gallus gallus A0A1D5P9X9 R-GGA-5623527 https://reactome.org/PathwayBrowser/#/R-GGA-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Gallus gallus A0A1D5P9Y4 R-GGA-3878123 https://reactome.org/PathwayBrowser/#/R-GGA-3878123 Initiation of SAHF formation IEA Gallus gallus A0A1D5P9Z8 R-GGA-176298 https://reactome.org/PathwayBrowser/#/R-GGA-176298 Activation of claspin IEA Gallus gallus A0A1D5P9Z8 R-GGA-176318 https://reactome.org/PathwayBrowser/#/R-GGA-176318 Loading of claspin onto DNA during replication origin firing IEA Gallus gallus A0A1D5P9Z8 R-GGA-68615 https://reactome.org/PathwayBrowser/#/R-GGA-68615 Formation of ORC(1-6) complex IEA Gallus gallus A0A1D5P9Z8 R-GGA-68688 https://reactome.org/PathwayBrowser/#/R-GGA-68688 CDC6 association with ORC(1-6) at replication origins IEA Gallus gallus A0A1D5P9Z8 R-GGA-68914 https://reactome.org/PathwayBrowser/#/R-GGA-68914 DNA polymerase alpha:primase binds at the origin IEA Gallus gallus A0A1D5P9Z8 R-GGA-68916 https://reactome.org/PathwayBrowser/#/R-GGA-68916 DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin IEA Gallus gallus A0A1D5P9Z8 R-GGA-68917 https://reactome.org/PathwayBrowser/#/R-GGA-68917 Cdc45 associates with the pre-replicative complex at the origin IEA Gallus gallus A0A1D5P9Z8 R-GGA-68918 https://reactome.org/PathwayBrowser/#/R-GGA-68918 CDK and DDK associate with the Mcm10:pre-replicative complex IEA Gallus gallus A0A1D5P9Z8 R-GGA-68919 https://reactome.org/PathwayBrowser/#/R-GGA-68919 Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 IEA Gallus gallus A0A1D5P9Z8 R-GGA-68940 https://reactome.org/PathwayBrowser/#/R-GGA-68940 Cdt1 is displaced from the pre-replicative complex IEA Gallus gallus A0A1D5P9Z8 R-GGA-68944 https://reactome.org/PathwayBrowser/#/R-GGA-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Gallus gallus A0A1D5P9Z8 R-GGA-68960 https://reactome.org/PathwayBrowser/#/R-GGA-68960 DNA polymerase epsilon binds at the origin IEA Gallus gallus A0A1D5P9Z8 R-GGA-9734670 https://reactome.org/PathwayBrowser/#/R-GGA-9734670 ORC6 binds KPNA1 or KPNA6 IEA Gallus gallus A0A1D5P9Z8 R-GGA-9734687 https://reactome.org/PathwayBrowser/#/R-GGA-9734687 ORC6 is phosphorylated on T195 IEA Gallus gallus A0A1D5P9Z8 R-GGA-9734713 https://reactome.org/PathwayBrowser/#/R-GGA-9734713 ORC6 translocates to the nucleus IEA Gallus gallus A0A1D5PA06 R-GGA-6791222 https://reactome.org/PathwayBrowser/#/R-GGA-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Gallus gallus A0A1D5PA06 R-GGA-6791227 https://reactome.org/PathwayBrowser/#/R-GGA-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Gallus gallus A0A1D5PA08 R-GGA-2028589 https://reactome.org/PathwayBrowser/#/R-GGA-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Gallus gallus A0A1D5PA08 R-GGA-2028591 https://reactome.org/PathwayBrowser/#/R-GGA-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Gallus gallus A0A1D5PA08 R-GGA-2028635 https://reactome.org/PathwayBrowser/#/R-GGA-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Gallus gallus A0A1D5PA08 R-GGA-2028673 https://reactome.org/PathwayBrowser/#/R-GGA-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Gallus gallus A0A1D5PA08 R-GGA-2028675 https://reactome.org/PathwayBrowser/#/R-GGA-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Gallus gallus A0A1D5PA08 R-GGA-2028697 https://reactome.org/PathwayBrowser/#/R-GGA-2028697 Cleavage of p-STK3 (p-MST2) by caspase 3 IEA Gallus gallus A0A1D5PA09 R-GGA-1222516 https://reactome.org/PathwayBrowser/#/R-GGA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Gallus gallus A0A1D5PA09 R-GGA-74723 https://reactome.org/PathwayBrowser/#/R-GGA-74723 Endosome acidification IEA Gallus gallus A0A1D5PA09 R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus A0A1D5PA09 R-GGA-9639286 https://reactome.org/PathwayBrowser/#/R-GGA-9639286 RRAGC,D exchanges GTP for GDP IEA Gallus gallus A0A1D5PA09 R-GGA-9640167 https://reactome.org/PathwayBrowser/#/R-GGA-9640167 RRAGA,B exchanges GDP for GTP IEA Gallus gallus A0A1D5PA09 R-GGA-9640168 https://reactome.org/PathwayBrowser/#/R-GGA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Gallus gallus A0A1D5PA09 R-GGA-9640175 https://reactome.org/PathwayBrowser/#/R-GGA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Gallus gallus A0A1D5PA09 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus A0A1D5PA09 R-GGA-9645598 https://reactome.org/PathwayBrowser/#/R-GGA-9645598 RRAGC,D hydrolyzes GTP IEA Gallus gallus A0A1D5PA09 R-GGA-9645608 https://reactome.org/PathwayBrowser/#/R-GGA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Gallus gallus A0A1D5PA09 R-GGA-9646468 https://reactome.org/PathwayBrowser/#/R-GGA-9646468 mTORC1 binds RHEB:GTP IEA Gallus gallus A0A1D5PA12 R-GGA-376419 https://reactome.org/PathwayBrowser/#/R-GGA-376419 Formation of NR-MED1 Coactivator Complex IEA Gallus gallus A0A1D5PA12 R-GGA-382096 https://reactome.org/PathwayBrowser/#/R-GGA-382096 Formation of NR-NCOR Corepressor Complex IEA Gallus gallus A0A1D5PA18 R-GGA-6805546 https://reactome.org/PathwayBrowser/#/R-GGA-6805546 Keratin type I binds keratin type II IEA Gallus gallus A0A1D5PA18 R-GGA-6805573 https://reactome.org/PathwayBrowser/#/R-GGA-6805573 Keratin type I/type II heterodimers form tetramers IEA Gallus gallus A0A1D5PA18 R-GGA-6806610 https://reactome.org/PathwayBrowser/#/R-GGA-6806610 Keratin filament formation IEA Gallus gallus A0A1D5PA18 R-GGA-6806613 https://reactome.org/PathwayBrowser/#/R-GGA-6806613 Keratin tetramers bind to form unit length filaments IEA Gallus gallus A0A1D5PA18 R-GGA-6806629 https://reactome.org/PathwayBrowser/#/R-GGA-6806629 Formation of tonofilament bundles IEA Gallus gallus A0A1D5PA18 R-GGA-6809393 https://reactome.org/PathwayBrowser/#/R-GGA-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Gallus gallus A0A1D5PA18 R-GGA-6810357 https://reactome.org/PathwayBrowser/#/R-GGA-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Gallus gallus A0A1D5PA60 R-GGA-9825759 https://reactome.org/PathwayBrowser/#/R-GGA-9825759 MAPK-dependent phosphorylation of KARS IEA Gallus gallus A0A1D5PA69 R-GGA-8847880 https://reactome.org/PathwayBrowser/#/R-GGA-8847880 CYTH proteins bind ARF1:GTP IEA Gallus gallus A0A1D5PA69 R-GGA-8847883 https://reactome.org/PathwayBrowser/#/R-GGA-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Gallus gallus A0A1D5PA75 R-GGA-5250930 https://reactome.org/PathwayBrowser/#/R-GGA-5250930 B-WICH recruits histone acetyltransferases IEA Gallus gallus A0A1D5PA75 R-GGA-5250938 https://reactome.org/PathwayBrowser/#/R-GGA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Gallus gallus A0A1D5PA75 R-GGA-5250947 https://reactome.org/PathwayBrowser/#/R-GGA-5250947 B-WICH complex binds rDNA promoter IEA Gallus gallus A0A1D5PA75 R-GGA-5683930 https://reactome.org/PathwayBrowser/#/R-GGA-5683930 WICH phosphorylates H2AFX on Y142 IEA Gallus gallus A0A1D5PA81 R-GGA-432065 https://reactome.org/PathwayBrowser/#/R-GGA-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Gallus gallus A0A1D5PA81 R-GGA-432232 https://reactome.org/PathwayBrowser/#/R-GGA-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Gallus gallus A0A1D5PA81 R-GGA-432237 https://reactome.org/PathwayBrowser/#/R-GGA-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Gallus gallus A0A1D5PA81 R-GGA-507868 https://reactome.org/PathwayBrowser/#/R-GGA-507868 Aquaporins passively transport water into cells IEA Gallus gallus A0A1D5PA81 R-GGA-507870 https://reactome.org/PathwayBrowser/#/R-GGA-507870 Aquaporins passively transport water out of cells IEA Gallus gallus A0A1D5PA94 R-GGA-1296127 https://reactome.org/PathwayBrowser/#/R-GGA-1296127 Activation of voltage gated Potassium channels IEA Gallus gallus A0A1D5PA98 R-GGA-109699 https://reactome.org/PathwayBrowser/#/R-GGA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Gallus gallus A0A1D5PA98 R-GGA-1306957 https://reactome.org/PathwayBrowser/#/R-GGA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Gallus gallus A0A1D5PA98 R-GGA-1306963 https://reactome.org/PathwayBrowser/#/R-GGA-1306963 Binding of GRB2:GAB1 to p-ERBB2:p-EGFR IEA Gallus gallus A0A1D5PA98 R-GGA-1306965 https://reactome.org/PathwayBrowser/#/R-GGA-1306965 Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Gallus gallus A0A1D5PA98 R-GGA-177920 https://reactome.org/PathwayBrowser/#/R-GGA-177920 Binding of GRB2 to GAB1 IEA Gallus gallus A0A1D5PA98 R-GGA-177923 https://reactome.org/PathwayBrowser/#/R-GGA-177923 Sustained activation of SRC kinase by SHP2 IEA Gallus gallus A0A1D5PA98 R-GGA-177924 https://reactome.org/PathwayBrowser/#/R-GGA-177924 Dephosphorylation of Gab1 by SHP2 IEA Gallus gallus A0A1D5PA98 R-GGA-177926 https://reactome.org/PathwayBrowser/#/R-GGA-177926 Dephosphorylation of PAG by SHP2 IEA Gallus gallus A0A1D5PA98 R-GGA-177927 https://reactome.org/PathwayBrowser/#/R-GGA-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 IEA Gallus gallus A0A1D5PA98 R-GGA-177930 https://reactome.org/PathwayBrowser/#/R-GGA-177930 GAB1 phosphorylation by EGFR kinase IEA Gallus gallus A0A1D5PA98 R-GGA-177931 https://reactome.org/PathwayBrowser/#/R-GGA-177931 Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 IEA Gallus gallus A0A1D5PA98 R-GGA-177935 https://reactome.org/PathwayBrowser/#/R-GGA-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Gallus gallus A0A1D5PA98 R-GGA-177939 https://reactome.org/PathwayBrowser/#/R-GGA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Gallus gallus A0A1D5PA98 R-GGA-177941 https://reactome.org/PathwayBrowser/#/R-GGA-177941 GRB2:GAB1 binds to phosphorylated EGFR IEA Gallus gallus A0A1D5PA98 R-GGA-177944 https://reactome.org/PathwayBrowser/#/R-GGA-177944 Activation of SHP2 through the binding to phospho-Gab1 IEA Gallus gallus A0A1D5PA98 R-GGA-179467 https://reactome.org/PathwayBrowser/#/R-GGA-179467 GAB1 binds phosphatidylinositol-3,4,5-trisphosphate IEA Gallus gallus A0A1D5PA98 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PA98 R-GGA-5654591 https://reactome.org/PathwayBrowser/#/R-GGA-5654591 Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Gallus gallus A0A1D5PA98 R-GGA-5654592 https://reactome.org/PathwayBrowser/#/R-GGA-5654592 Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Gallus gallus A0A1D5PA98 R-GGA-5654594 https://reactome.org/PathwayBrowser/#/R-GGA-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Gallus gallus A0A1D5PA98 R-GGA-5654596 https://reactome.org/PathwayBrowser/#/R-GGA-5654596 Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Gallus gallus A0A1D5PA98 R-GGA-5654612 https://reactome.org/PathwayBrowser/#/R-GGA-5654612 Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Gallus gallus A0A1D5PA98 R-GGA-5654614 https://reactome.org/PathwayBrowser/#/R-GGA-5654614 Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Gallus gallus A0A1D5PA98 R-GGA-5654620 https://reactome.org/PathwayBrowser/#/R-GGA-5654620 Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Gallus gallus A0A1D5PA98 R-GGA-5654622 https://reactome.org/PathwayBrowser/#/R-GGA-5654622 Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Gallus gallus A0A1D5PA98 R-GGA-5654637 https://reactome.org/PathwayBrowser/#/R-GGA-5654637 Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Gallus gallus A0A1D5PA98 R-GGA-5654640 https://reactome.org/PathwayBrowser/#/R-GGA-5654640 Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Gallus gallus A0A1D5PA98 R-GGA-5654641 https://reactome.org/PathwayBrowser/#/R-GGA-5654641 Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Gallus gallus A0A1D5PA98 R-GGA-5654643 https://reactome.org/PathwayBrowser/#/R-GGA-5654643 Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Gallus gallus A0A1D5PA98 R-GGA-5654659 https://reactome.org/PathwayBrowser/#/R-GGA-5654659 Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Gallus gallus A0A1D5PA98 R-GGA-5654662 https://reactome.org/PathwayBrowser/#/R-GGA-5654662 Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Gallus gallus A0A1D5PA98 R-GGA-5654667 https://reactome.org/PathwayBrowser/#/R-GGA-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Gallus gallus A0A1D5PA98 R-GGA-5654669 https://reactome.org/PathwayBrowser/#/R-GGA-5654669 Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA IEA Gallus gallus A0A1D5PA98 R-GGA-5654690 https://reactome.org/PathwayBrowser/#/R-GGA-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PA98 R-GGA-5654692 https://reactome.org/PathwayBrowser/#/R-GGA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PA98 R-GGA-5654697 https://reactome.org/PathwayBrowser/#/R-GGA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PA98 R-GGA-5654701 https://reactome.org/PathwayBrowser/#/R-GGA-5654701 FGFR2-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PA98 R-GGA-5654705 https://reactome.org/PathwayBrowser/#/R-GGA-5654705 FGFR3-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PA98 R-GGA-5654709 https://reactome.org/PathwayBrowser/#/R-GGA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PA98 R-GGA-5654714 https://reactome.org/PathwayBrowser/#/R-GGA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PA98 R-GGA-5654717 https://reactome.org/PathwayBrowser/#/R-GGA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PA98 R-GGA-8851908 https://reactome.org/PathwayBrowser/#/R-GGA-8851908 Activated MET binds GAB1 IEA Gallus gallus A0A1D5PA98 R-GGA-8851919 https://reactome.org/PathwayBrowser/#/R-GGA-8851919 Activated MET binds GAB1 and GRB2 IEA Gallus gallus A0A1D5PA98 R-GGA-8851933 https://reactome.org/PathwayBrowser/#/R-GGA-8851933 MET phosphorylates GAB1 IEA Gallus gallus A0A1D5PA98 R-GGA-8851954 https://reactome.org/PathwayBrowser/#/R-GGA-8851954 Phosphorylated GAB1 recruits PI3K to MET IEA Gallus gallus A0A1D5PA98 R-GGA-8852019 https://reactome.org/PathwayBrowser/#/R-GGA-8852019 MET bound PI3K generates PIP3 IEA Gallus gallus A0A1D5PA98 R-GGA-8853774 https://reactome.org/PathwayBrowser/#/R-GGA-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Gallus gallus A0A1D5PA98 R-GGA-8854897 https://reactome.org/PathwayBrowser/#/R-GGA-8854897 p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2 IEA Gallus gallus A0A1D5PA98 R-GGA-8854905 https://reactome.org/PathwayBrowser/#/R-GGA-8854905 p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K IEA Gallus gallus A0A1D5PA98 R-GGA-8855508 https://reactome.org/PathwayBrowser/#/R-GGA-8855508 p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 IEA Gallus gallus A0A1D5PA98 R-GGA-8865994 https://reactome.org/PathwayBrowser/#/R-GGA-8865994 GAB1 binds PTPN11 IEA Gallus gallus A0A1D5PA98 R-GGA-8875540 https://reactome.org/PathwayBrowser/#/R-GGA-8875540 GAB1 recruits CRK,CRKL to MET IEA Gallus gallus A0A1D5PA98 R-GGA-8875558 https://reactome.org/PathwayBrowser/#/R-GGA-8875558 RAPGEF1 binds CRK,CRKL IEA Gallus gallus A0A1D5PA98 R-GGA-8875568 https://reactome.org/PathwayBrowser/#/R-GGA-8875568 RAPGEF1 activates RAP1 IEA Gallus gallus A0A1D5PA98 R-GGA-8875576 https://reactome.org/PathwayBrowser/#/R-GGA-8875576 CRK,CRKL recruits RAC1 GEF to activated MET IEA Gallus gallus A0A1D5PA98 R-GGA-8875591 https://reactome.org/PathwayBrowser/#/R-GGA-8875591 DOCK7 activates RAC1 IEA Gallus gallus A0A1D5PA98 R-GGA-8875659 https://reactome.org/PathwayBrowser/#/R-GGA-8875659 RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane IEA Gallus gallus A0A1D5PA98 R-GGA-8875661 https://reactome.org/PathwayBrowser/#/R-GGA-8875661 GGA3 associates with activated MET receptor IEA Gallus gallus A0A1D5PAA3 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1D5PAA3 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5PAA3 R-GGA-420724 https://reactome.org/PathwayBrowser/#/R-GGA-420724 CASR binds Ca2+ IEA Gallus gallus A0A1D5PAA3 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1D5PAA3 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1D5PAA3 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5PAA3 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5PAA3 R-GGA-9703895 https://reactome.org/PathwayBrowser/#/R-GGA-9703895 CASR binds CASR agonists IEA Gallus gallus A0A1D5PAA8 R-GGA-3322001 https://reactome.org/PathwayBrowser/#/R-GGA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Gallus gallus A0A1D5PAA8 R-GGA-3322003 https://reactome.org/PathwayBrowser/#/R-GGA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Gallus gallus A0A1D5PAA8 R-GGA-3322005 https://reactome.org/PathwayBrowser/#/R-GGA-3322005 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a IEA Gallus gallus A0A1D5PAA8 R-GGA-3322025 https://reactome.org/PathwayBrowser/#/R-GGA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Gallus gallus A0A1D5PAA8 R-GGA-3322041 https://reactome.org/PathwayBrowser/#/R-GGA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Gallus gallus A0A1D5PAA8 R-GGA-3322057 https://reactome.org/PathwayBrowser/#/R-GGA-3322057 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b IEA Gallus gallus A0A1D5PAA8 R-GGA-3781018 https://reactome.org/PathwayBrowser/#/R-GGA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Gallus gallus A0A1D5PAA8 R-GGA-3781023 https://reactome.org/PathwayBrowser/#/R-GGA-3781023 PPP1R3C binds to glycogen:GYG1:GYS1 IEA Gallus gallus A0A1D5PAA8 R-GGA-3781024 https://reactome.org/PathwayBrowser/#/R-GGA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Gallus gallus A0A1D5PAA8 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PAA8 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PAA8 R-GGA-71552 https://reactome.org/PathwayBrowser/#/R-GGA-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin IEA Gallus gallus A0A1D5PAA8 R-GGA-71593 https://reactome.org/PathwayBrowser/#/R-GGA-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Gallus gallus A0A1D5PAB0 R-GGA-2029476 https://reactome.org/PathwayBrowser/#/R-GGA-2029476 Role of myosins in phagosome formation IEA Gallus gallus A0A1D5PAB0 R-GGA-9856465 https://reactome.org/PathwayBrowser/#/R-GGA-9856465 MLPH/MYRIP bind GGC-RAB27A and MYO5A IEA Gallus gallus A0A1D5PAB3 R-GGA-1614362 https://reactome.org/PathwayBrowser/#/R-GGA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Gallus gallus A0A1D5PAC2 R-GGA-9609921 https://reactome.org/PathwayBrowser/#/R-GGA-9609921 SGTA binds Tail-anchored protein IEA Gallus gallus A0A1D5PAD6 R-GGA-201510 https://reactome.org/PathwayBrowser/#/R-GGA-201510 PI3K synthesizes PIP3 downstream of ALK IEA Gallus gallus A0A1D5PAD6 R-GGA-201515 https://reactome.org/PathwayBrowser/#/R-GGA-201515 Active ALK recruits PI3K IEA Gallus gallus A0A1D5PAD6 R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus A0A1D5PAD6 R-GGA-9700149 https://reactome.org/PathwayBrowser/#/R-GGA-9700149 Active ALK binds PLCG1 IEA Gallus gallus A0A1D5PAD6 R-GGA-9700154 https://reactome.org/PathwayBrowser/#/R-GGA-9700154 Active ALK binds SHC1 IEA Gallus gallus A0A1D5PAD6 R-GGA-9700156 https://reactome.org/PathwayBrowser/#/R-GGA-9700156 Active ALK dimer binds IRS1 IEA Gallus gallus A0A1D5PAD6 R-GGA-9700168 https://reactome.org/PathwayBrowser/#/R-GGA-9700168 Active ALK phosphorylates IRS1 IEA Gallus gallus A0A1D5PAD6 R-GGA-9700171 https://reactome.org/PathwayBrowser/#/R-GGA-9700171 Active ALK phosphorylates PLCG1 IEA Gallus gallus A0A1D5PAD6 R-GGA-9700175 https://reactome.org/PathwayBrowser/#/R-GGA-9700175 Active ALK phosphorylates SHC1 IEA Gallus gallus A0A1D5PAD6 R-GGA-9700662 https://reactome.org/PathwayBrowser/#/R-GGA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Gallus gallus A0A1D5PAD6 R-GGA-9701524 https://reactome.org/PathwayBrowser/#/R-GGA-9701524 STAT3 is phosphorylated downstream of active ALK IEA Gallus gallus A0A1D5PAD6 R-GGA-9842641 https://reactome.org/PathwayBrowser/#/R-GGA-9842641 Active LTK receptor binds SHC1 IEA Gallus gallus A0A1D5PAD6 R-GGA-9842648 https://reactome.org/PathwayBrowser/#/R-GGA-9842648 Autophosphorylation of LTK dimer:ALKAL1,2 IEA Gallus gallus A0A1D5PAD6 R-GGA-9842649 https://reactome.org/PathwayBrowser/#/R-GGA-9842649 Active LTK receptor binds PI3K IEA Gallus gallus A0A1D5PAD6 R-GGA-9842651 https://reactome.org/PathwayBrowser/#/R-GGA-9842651 Active LTK receptor phosphorylates SHC1 IEA Gallus gallus A0A1D5PAD6 R-GGA-9842655 https://reactome.org/PathwayBrowser/#/R-GGA-9842655 IRS1 recruits GRB2 to active LTK IEA Gallus gallus A0A1D5PAD6 R-GGA-9842656 https://reactome.org/PathwayBrowser/#/R-GGA-9842656 ALK binds ALKAL ligand IEA Gallus gallus A0A1D5PAD6 R-GGA-9842660 https://reactome.org/PathwayBrowser/#/R-GGA-9842660 LTK binds ALKAL ligand IEA Gallus gallus A0A1D5PAD6 R-GGA-9842665 https://reactome.org/PathwayBrowser/#/R-GGA-9842665 Active LTK binds GRB2:TNK2 IEA Gallus gallus A0A1D5PAD6 R-GGA-9842666 https://reactome.org/PathwayBrowser/#/R-GGA-9842666 Active LTK phosphorylates IRS1 IEA Gallus gallus A0A1D5PAD6 R-GGA-9842669 https://reactome.org/PathwayBrowser/#/R-GGA-9842669 Active LTK recruits GRB2:SOS1 IEA Gallus gallus A0A1D5PAD6 R-GGA-9842671 https://reactome.org/PathwayBrowser/#/R-GGA-9842671 Active LTK binds IRS1 IEA Gallus gallus A0A1D5PAE3 R-GGA-1605591 https://reactome.org/PathwayBrowser/#/R-GGA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Gallus gallus A0A1D5PAE3 R-GGA-1605624 https://reactome.org/PathwayBrowser/#/R-GGA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Gallus gallus A0A1D5PAE3 R-GGA-1605632 https://reactome.org/PathwayBrowser/#/R-GGA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Gallus gallus A0A1D5PAE3 R-GGA-1605724 https://reactome.org/PathwayBrowser/#/R-GGA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Gallus gallus A0A1D5PAE3 R-GGA-1605736 https://reactome.org/PathwayBrowser/#/R-GGA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Gallus gallus A0A1D5PAE3 R-GGA-1606312 https://reactome.org/PathwayBrowser/#/R-GGA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Gallus gallus A0A1D5PAE3 R-GGA-1606564 https://reactome.org/PathwayBrowser/#/R-GGA-1606564 GALC hydrolyzes GalCer IEA Gallus gallus A0A1D5PAE3 R-GGA-1606602 https://reactome.org/PathwayBrowser/#/R-GGA-1606602 ASAH1 hydrolyzes ceramide IEA Gallus gallus A0A1D5PAE3 R-GGA-1606807 https://reactome.org/PathwayBrowser/#/R-GGA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Gallus gallus A0A1D5PAE3 R-GGA-351341 https://reactome.org/PathwayBrowser/#/R-GGA-351341 Exocytosis of Proactivator polypeptide IEA Gallus gallus A0A1D5PAE3 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5PAE3 R-GGA-5336182 https://reactome.org/PathwayBrowser/#/R-GGA-5336182 GPR37 binds prosaptide IEA Gallus gallus A0A1D5PAE3 R-GGA-5336184 https://reactome.org/PathwayBrowser/#/R-GGA-5336184 GPR37L binds prosaposin IEA Gallus gallus A0A1D5PAE3 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5PAE3 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5PAE3 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5PAE3 R-GGA-9840334 https://reactome.org/PathwayBrowser/#/R-GGA-9840334 PSAP gets cleaved IEA Gallus gallus A0A1D5PAE3 R-GGA-9840470 https://reactome.org/PathwayBrowser/#/R-GGA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Gallus gallus A0A1D5PAE3 R-GGA-9840488 https://reactome.org/PathwayBrowser/#/R-GGA-9840488 PSAP(195-273) forms a dimer IEA Gallus gallus A0A1D5PAE3 R-GGA-9841189 https://reactome.org/PathwayBrowser/#/R-GGA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Gallus gallus A0A1D5PAE3 R-GGA-9842115 https://reactome.org/PathwayBrowser/#/R-GGA-9842115 PSAP(195-273) dimer binds PE IEA Gallus gallus A0A1D5PAE7 R-GGA-112385 https://reactome.org/PathwayBrowser/#/R-GGA-112385 Addition of nucleotides leads to transcript elongation IEA Gallus gallus A0A1D5PAE7 R-GGA-112392 https://reactome.org/PathwayBrowser/#/R-GGA-112392 Resumption of elongation after recovery from pausing IEA Gallus gallus A0A1D5PAE7 R-GGA-112395 https://reactome.org/PathwayBrowser/#/R-GGA-112395 Abortive termination of elongation after arrest IEA Gallus gallus A0A1D5PAE7 R-GGA-112396 https://reactome.org/PathwayBrowser/#/R-GGA-112396 Separation of elongating transcript from template IEA Gallus gallus A0A1D5PAE7 R-GGA-113411 https://reactome.org/PathwayBrowser/#/R-GGA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Gallus gallus A0A1D5PAE7 R-GGA-113412 https://reactome.org/PathwayBrowser/#/R-GGA-113412 Pol II elongation complex moves on the template as transcript elongates IEA Gallus gallus A0A1D5PAE7 R-GGA-113413 https://reactome.org/PathwayBrowser/#/R-GGA-113413 TFIIS-mediated recovery of elongation from arrest IEA Gallus gallus A0A1D5PAE7 R-GGA-113414 https://reactome.org/PathwayBrowser/#/R-GGA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Gallus gallus A0A1D5PAE7 R-GGA-6797606 https://reactome.org/PathwayBrowser/#/R-GGA-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Gallus gallus A0A1D5PAE7 R-GGA-6797616 https://reactome.org/PathwayBrowser/#/R-GGA-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Gallus gallus A0A1D5PAE8 R-GGA-266072 https://reactome.org/PathwayBrowser/#/R-GGA-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Gallus gallus A0A1D5PAE8 R-GGA-6798745 https://reactome.org/PathwayBrowser/#/R-GGA-6798745 Exocytosis of tertiary granule lumen proteins IEA Gallus gallus A0A1D5PAE8 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PAE8 R-GGA-9018862 https://reactome.org/PathwayBrowser/#/R-GGA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Gallus gallus A0A1D5PAE8 R-GGA-9018877 https://reactome.org/PathwayBrowser/#/R-GGA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Gallus gallus A0A1D5PAE8 R-GGA-9020252 https://reactome.org/PathwayBrowser/#/R-GGA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Gallus gallus A0A1D5PAE8 R-GGA-9020253 https://reactome.org/PathwayBrowser/#/R-GGA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Gallus gallus A0A1D5PAE8 R-GGA-9020257 https://reactome.org/PathwayBrowser/#/R-GGA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Gallus gallus A0A1D5PAE8 R-GGA-9020258 https://reactome.org/PathwayBrowser/#/R-GGA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Gallus gallus A0A1D5PAE8 R-GGA-9020270 https://reactome.org/PathwayBrowser/#/R-GGA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Gallus gallus A0A1D5PAE8 R-GGA-9024890 https://reactome.org/PathwayBrowser/#/R-GGA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Gallus gallus A0A1D5PAF6 R-GGA-481007 https://reactome.org/PathwayBrowser/#/R-GGA-481007 Exocytosis of platelet alpha granule contents IEA Gallus gallus A0A1D5PAF7 R-GGA-426032 https://reactome.org/PathwayBrowser/#/R-GGA-426032 DAG is metabolized by DAGL to 2-AG IEA Gallus gallus A0A1D5PAF9 R-GGA-421831 https://reactome.org/PathwayBrowser/#/R-GGA-421831 trans-Golgi Network Coat Assembly IEA Gallus gallus A0A1D5PAF9 R-GGA-421835 https://reactome.org/PathwayBrowser/#/R-GGA-421835 trans-Golgi Network Vesicle Scission IEA Gallus gallus A0A1D5PAG0 R-GGA-191763 https://reactome.org/PathwayBrowser/#/R-GGA-191763 snRNP:Snurportin complex formation IEA Gallus gallus A0A1D5PAG0 R-GGA-191784 https://reactome.org/PathwayBrowser/#/R-GGA-191784 snRNA Cap hypermethylation IEA Gallus gallus A0A1D5PAG0 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1D5PAI1 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5PAI1 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5PAI1 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5PAI1 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5PAI1 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5PAI8 R-GGA-1028788 https://reactome.org/PathwayBrowser/#/R-GGA-1028788 FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP IEA Gallus gallus A0A1D5PAJ8 R-GGA-1222516 https://reactome.org/PathwayBrowser/#/R-GGA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Gallus gallus A0A1D5PAJ8 R-GGA-74723 https://reactome.org/PathwayBrowser/#/R-GGA-74723 Endosome acidification IEA Gallus gallus A0A1D5PAJ8 R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus A0A1D5PAJ8 R-GGA-9639286 https://reactome.org/PathwayBrowser/#/R-GGA-9639286 RRAGC,D exchanges GTP for GDP IEA Gallus gallus A0A1D5PAJ8 R-GGA-9640167 https://reactome.org/PathwayBrowser/#/R-GGA-9640167 RRAGA,B exchanges GDP for GTP IEA Gallus gallus A0A1D5PAJ8 R-GGA-9640168 https://reactome.org/PathwayBrowser/#/R-GGA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Gallus gallus A0A1D5PAJ8 R-GGA-9640175 https://reactome.org/PathwayBrowser/#/R-GGA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Gallus gallus A0A1D5PAJ8 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus A0A1D5PAJ8 R-GGA-9645598 https://reactome.org/PathwayBrowser/#/R-GGA-9645598 RRAGC,D hydrolyzes GTP IEA Gallus gallus A0A1D5PAJ8 R-GGA-9645608 https://reactome.org/PathwayBrowser/#/R-GGA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Gallus gallus A0A1D5PAJ8 R-GGA-9646468 https://reactome.org/PathwayBrowser/#/R-GGA-9646468 mTORC1 binds RHEB:GTP IEA Gallus gallus A0A1D5PAJ9 R-GGA-9018766 https://reactome.org/PathwayBrowser/#/R-GGA-9018766 RHOU binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PAJ9 R-GGA-9018794 https://reactome.org/PathwayBrowser/#/R-GGA-9018794 RHOV binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PAJ9 R-GGA-9696266 https://reactome.org/PathwayBrowser/#/R-GGA-9696266 RND2 binds effectors IEA Gallus gallus A0A1D5PAJ9 R-GGA-9696268 https://reactome.org/PathwayBrowser/#/R-GGA-9696268 RND3 binds effectors IEA Gallus gallus A0A1D5PAJ9 R-GGA-9696271 https://reactome.org/PathwayBrowser/#/R-GGA-9696271 RND1 binds effectors IEA Gallus gallus A0A1D5PAK0 R-GGA-2002428 https://reactome.org/PathwayBrowser/#/R-GGA-2002428 Removal of fibrillar collagen N-propeptides IEA Gallus gallus A0A1D5PAK0 R-GGA-5173005 https://reactome.org/PathwayBrowser/#/R-GGA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Gallus gallus A0A1D5PAK0 R-GGA-5173192 https://reactome.org/PathwayBrowser/#/R-GGA-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Gallus gallus A0A1D5PAK5 R-GGA-9865630 https://reactome.org/PathwayBrowser/#/R-GGA-9865630 Metallochaperone inserts 2Cu2+ into MT-CO2 IEA Gallus gallus A0A1D5PAK5 R-GGA-9902096 https://reactome.org/PathwayBrowser/#/R-GGA-9902096 COX18 inserts nascent MT-CO2 in COX20:TMEM77 IEA Gallus gallus A0A1D5PAK6 R-GGA-5615637 https://reactome.org/PathwayBrowser/#/R-GGA-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Gallus gallus A0A1D5PAL2 R-GGA-1678921 https://reactome.org/PathwayBrowser/#/R-GGA-1678921 Full-length TLR3/7/8/9 binds to UNC93B1 IEA Gallus gallus A0A1D5PAL2 R-GGA-1678998 https://reactome.org/PathwayBrowser/#/R-GGA-1678998 Endosomal TLRs pass through the Golgi IEA Gallus gallus A0A1D5PAL6 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PAL6 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PAL6 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PAL6 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PAM1 R-GGA-5683735 https://reactome.org/PathwayBrowser/#/R-GGA-5683735 CHEK2 is recruited to DNA DSBs IEA Gallus gallus A0A1D5PAM1 R-GGA-5683774 https://reactome.org/PathwayBrowser/#/R-GGA-5683774 p-T68-CHEK2 dimerizes IEA Gallus gallus A0A1D5PAM1 R-GGA-5683792 https://reactome.org/PathwayBrowser/#/R-GGA-5683792 p-T68-CHEK2 autophosphorylates IEA Gallus gallus A0A1D5PAM1 R-GGA-5683801 https://reactome.org/PathwayBrowser/#/R-GGA-5683801 CHEK2 phosphorylates BRCA1 IEA Gallus gallus A0A1D5PAM1 R-GGA-69608 https://reactome.org/PathwayBrowser/#/R-GGA-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Gallus gallus A0A1D5PAM1 R-GGA-69891 https://reactome.org/PathwayBrowser/#/R-GGA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Gallus gallus A0A1D5PAM4 R-GGA-3371582 https://reactome.org/PathwayBrowser/#/R-GGA-3371582 HSBP1 binds HSF1 trimer IEA Gallus gallus A0A1D5PAM4 R-GGA-5082356 https://reactome.org/PathwayBrowser/#/R-GGA-5082356 HSF1-mediated gene expression IEA Gallus gallus A0A1D5PAN9 R-GGA-111439 https://reactome.org/PathwayBrowser/#/R-GGA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Gallus gallus A0A1D5PAN9 R-GGA-158441 https://reactome.org/PathwayBrowser/#/R-GGA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PAN9 R-GGA-158447 https://reactome.org/PathwayBrowser/#/R-GGA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Gallus gallus A0A1D5PAN9 R-GGA-158481 https://reactome.org/PathwayBrowser/#/R-GGA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PAN9 R-GGA-158484 https://reactome.org/PathwayBrowser/#/R-GGA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Gallus gallus A0A1D5PAN9 R-GGA-159046 https://reactome.org/PathwayBrowser/#/R-GGA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Gallus gallus A0A1D5PAN9 R-GGA-159050 https://reactome.org/PathwayBrowser/#/R-GGA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Gallus gallus A0A1D5PAN9 R-GGA-170825 https://reactome.org/PathwayBrowser/#/R-GGA-170825 NPC exports GCK1 from nucleus IEA Gallus gallus A0A1D5PAN9 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1D5PAN9 R-GGA-2990880 https://reactome.org/PathwayBrowser/#/R-GGA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Gallus gallus A0A1D5PAN9 R-GGA-2990882 https://reactome.org/PathwayBrowser/#/R-GGA-2990882 CDK1 phosphorylates NUP98 IEA Gallus gallus A0A1D5PAN9 R-GGA-4551649 https://reactome.org/PathwayBrowser/#/R-GGA-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Gallus gallus A0A1D5PAN9 R-GGA-4551679 https://reactome.org/PathwayBrowser/#/R-GGA-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Gallus gallus A0A1D5PAN9 R-GGA-4615872 https://reactome.org/PathwayBrowser/#/R-GGA-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Gallus gallus A0A1D5PAN9 R-GGA-4615987 https://reactome.org/PathwayBrowser/#/R-GGA-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Gallus gallus A0A1D5PAN9 R-GGA-4655355 https://reactome.org/PathwayBrowser/#/R-GGA-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Gallus gallus A0A1D5PAN9 R-GGA-5228523 https://reactome.org/PathwayBrowser/#/R-GGA-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Gallus gallus A0A1D5PAN9 R-GGA-5578744 https://reactome.org/PathwayBrowser/#/R-GGA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Gallus gallus A0A1D5PAN9 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1D5PAN9 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1D5PAN9 R-GGA-77587 https://reactome.org/PathwayBrowser/#/R-GGA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Gallus gallus A0A1D5PAN9 R-GGA-9634169 https://reactome.org/PathwayBrowser/#/R-GGA-9634169 POM121 and NDC1 bind the Nup93 complex IEA Gallus gallus A0A1D5PAP3 R-GGA-1475022 https://reactome.org/PathwayBrowser/#/R-GGA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Gallus gallus A0A1D5PAP3 R-GGA-1475026 https://reactome.org/PathwayBrowser/#/R-GGA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Gallus gallus A0A1D5PAQ0 R-GGA-1112666 https://reactome.org/PathwayBrowser/#/R-GGA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Gallus gallus A0A1D5PAQ0 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus A0A1D5PAQ0 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus A0A1D5PAQ0 R-GGA-173626 https://reactome.org/PathwayBrowser/#/R-GGA-173626 Activation of C1r IEA Gallus gallus A0A1D5PAQ0 R-GGA-173631 https://reactome.org/PathwayBrowser/#/R-GGA-173631 Activation of C1s IEA Gallus gallus A0A1D5PAQ0 R-GGA-1861621 https://reactome.org/PathwayBrowser/#/R-GGA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Gallus gallus A0A1D5PAQ0 R-GGA-199161 https://reactome.org/PathwayBrowser/#/R-GGA-199161 Fc gamma receptors interact with antigen-bound IgG IEA Gallus gallus A0A1D5PAQ0 R-GGA-2029268 https://reactome.org/PathwayBrowser/#/R-GGA-2029268 Phosphorylation and activation of PLCG IEA Gallus gallus A0A1D5PAQ0 R-GGA-2029270 https://reactome.org/PathwayBrowser/#/R-GGA-2029270 Recruitment of PLCgamma to membrane IEA Gallus gallus A0A1D5PAQ0 R-GGA-2029271 https://reactome.org/PathwayBrowser/#/R-GGA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PAQ0 R-GGA-2029272 https://reactome.org/PathwayBrowser/#/R-GGA-2029272 Release of PLCG from FCGR IEA Gallus gallus A0A1D5PAQ0 R-GGA-2029273 https://reactome.org/PathwayBrowser/#/R-GGA-2029273 PI3K binds to p-6Y-SYK IEA Gallus gallus A0A1D5PAQ0 R-GGA-2029451 https://reactome.org/PathwayBrowser/#/R-GGA-2029451 Activation of RAC1 by VAV IEA Gallus gallus A0A1D5PAQ0 R-GGA-2029452 https://reactome.org/PathwayBrowser/#/R-GGA-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Gallus gallus A0A1D5PAQ0 R-GGA-2029453 https://reactome.org/PathwayBrowser/#/R-GGA-2029453 Phosphorylation of VAV IEA Gallus gallus A0A1D5PAQ0 R-GGA-2029455 https://reactome.org/PathwayBrowser/#/R-GGA-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Gallus gallus A0A1D5PAQ0 R-GGA-2029457 https://reactome.org/PathwayBrowser/#/R-GGA-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Gallus gallus A0A1D5PAQ0 R-GGA-2029458 https://reactome.org/PathwayBrowser/#/R-GGA-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Gallus gallus A0A1D5PAQ0 R-GGA-2029459 https://reactome.org/PathwayBrowser/#/R-GGA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Gallus gallus A0A1D5PAQ0 R-GGA-2029467 https://reactome.org/PathwayBrowser/#/R-GGA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Gallus gallus A0A1D5PAQ0 R-GGA-2029476 https://reactome.org/PathwayBrowser/#/R-GGA-2029476 Role of myosins in phagosome formation IEA Gallus gallus A0A1D5PAQ0 R-GGA-2197697 https://reactome.org/PathwayBrowser/#/R-GGA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Gallus gallus A0A1D5PAQ0 R-GGA-2203516 https://reactome.org/PathwayBrowser/#/R-GGA-2203516 Alpha-1-Microglobulin is cleaved IEA Gallus gallus A0A1D5PAQ0 R-GGA-8852266 https://reactome.org/PathwayBrowser/#/R-GGA-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Gallus gallus A0A1D5PAQ0 R-GGA-8852481 https://reactome.org/PathwayBrowser/#/R-GGA-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Gallus gallus A0A1D5PAQ0 R-GGA-8858428 https://reactome.org/PathwayBrowser/#/R-GGA-8858428 FCAMR binds IgA IEA Gallus gallus A0A1D5PAQ0 R-GGA-9021306 https://reactome.org/PathwayBrowser/#/R-GGA-9021306 C1-Inh binds and inactivates C1r, C1s IEA Gallus gallus A0A1D5PAQ0 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus A0A1D5PAQ0 R-GGA-9724685 https://reactome.org/PathwayBrowser/#/R-GGA-9724685 IgE binds omalizumab IEA Gallus gallus A0A1D5PAQ0 R-GGA-983696 https://reactome.org/PathwayBrowser/#/R-GGA-983696 The Immunoglobulin of the BCR binds antigen IEA Gallus gallus A0A1D5PAQ0 R-GGA-983700 https://reactome.org/PathwayBrowser/#/R-GGA-983700 SYK binds the activated BCR IEA Gallus gallus A0A1D5PAQ0 R-GGA-983703 https://reactome.org/PathwayBrowser/#/R-GGA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Gallus gallus A0A1D5PAQ0 R-GGA-983707 https://reactome.org/PathwayBrowser/#/R-GGA-983707 SYK autophosphorylates at the activated BCR IEA Gallus gallus A0A1D5PAQ3 R-GGA-446204 https://reactome.org/PathwayBrowser/#/R-GGA-446204 GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine IEA Gallus gallus A0A1D5PAR0 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PAR0 R-GGA-9693111 https://reactome.org/PathwayBrowser/#/R-GGA-9693111 RHOF auto-activates IEA Gallus gallus A0A1D5PAR0 R-GGA-9693125 https://reactome.org/PathwayBrowser/#/R-GGA-9693125 RHOF binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PAR0 R-GGA-9693282 https://reactome.org/PathwayBrowser/#/R-GGA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Gallus gallus A0A1D5PAR2 R-GGA-140216 https://reactome.org/PathwayBrowser/#/R-GGA-140216 Translocation of PMAIP1 (NOXA) to mitochondria IEA Gallus gallus A0A1D5PAR2 R-GGA-508162 https://reactome.org/PathwayBrowser/#/R-GGA-508162 BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL IEA Gallus gallus A0A1D5PAR2 R-GGA-508163 https://reactome.org/PathwayBrowser/#/R-GGA-508163 BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 IEA Gallus gallus A0A1D5PAR6 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PAR6 R-GGA-481007 https://reactome.org/PathwayBrowser/#/R-GGA-481007 Exocytosis of platelet alpha granule contents IEA Gallus gallus A0A1D5PAR6 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5PAR6 R-GGA-6800298 https://reactome.org/PathwayBrowser/#/R-GGA-6800298 HGF dimer binds MET IEA Gallus gallus A0A1D5PAR6 R-GGA-6800299 https://reactome.org/PathwayBrowser/#/R-GGA-6800299 HGFAC cleaves pro-HGF to form HGF dimer IEA Gallus gallus A0A1D5PAR6 R-GGA-6806957 https://reactome.org/PathwayBrowser/#/R-GGA-6806957 MET receptor dimerizes IEA Gallus gallus A0A1D5PAR6 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus A0A1D5PAR6 R-GGA-6807008 https://reactome.org/PathwayBrowser/#/R-GGA-6807008 PTPRJ dephosphorylates MET IEA Gallus gallus A0A1D5PAR6 R-GGA-6807027 https://reactome.org/PathwayBrowser/#/R-GGA-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Gallus gallus A0A1D5PAR6 R-GGA-8851804 https://reactome.org/PathwayBrowser/#/R-GGA-8851804 Activated MET recruits GRB2-1:SOS1 IEA Gallus gallus A0A1D5PAR6 R-GGA-8851827 https://reactome.org/PathwayBrowser/#/R-GGA-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Gallus gallus A0A1D5PAR6 R-GGA-8851866 https://reactome.org/PathwayBrowser/#/R-GGA-8851866 MET binds RANBP10 IEA Gallus gallus A0A1D5PAR6 R-GGA-8851877 https://reactome.org/PathwayBrowser/#/R-GGA-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Gallus gallus A0A1D5PAR6 R-GGA-8851888 https://reactome.org/PathwayBrowser/#/R-GGA-8851888 MET binds SHC1-2 IEA Gallus gallus A0A1D5PAR6 R-GGA-8851890 https://reactome.org/PathwayBrowser/#/R-GGA-8851890 MET phosphorylates SHC1-2 IEA Gallus gallus A0A1D5PAR6 R-GGA-8851899 https://reactome.org/PathwayBrowser/#/R-GGA-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Gallus gallus A0A1D5PAR6 R-GGA-8851900 https://reactome.org/PathwayBrowser/#/R-GGA-8851900 SHC1-2 bound to MET recruits GRB2:SOS1 IEA Gallus gallus A0A1D5PAR6 R-GGA-8851908 https://reactome.org/PathwayBrowser/#/R-GGA-8851908 Activated MET binds GAB1 IEA Gallus gallus A0A1D5PAR6 R-GGA-8851919 https://reactome.org/PathwayBrowser/#/R-GGA-8851919 Activated MET binds GAB1 and GRB2 IEA Gallus gallus A0A1D5PAR6 R-GGA-8851933 https://reactome.org/PathwayBrowser/#/R-GGA-8851933 MET phosphorylates GAB1 IEA Gallus gallus A0A1D5PAR6 R-GGA-8851954 https://reactome.org/PathwayBrowser/#/R-GGA-8851954 Phosphorylated GAB1 recruits PI3K to MET IEA Gallus gallus A0A1D5PAR6 R-GGA-8852019 https://reactome.org/PathwayBrowser/#/R-GGA-8852019 MET bound PI3K generates PIP3 IEA Gallus gallus A0A1D5PAR6 R-GGA-8865994 https://reactome.org/PathwayBrowser/#/R-GGA-8865994 GAB1 binds PTPN11 IEA Gallus gallus A0A1D5PAR6 R-GGA-8874078 https://reactome.org/PathwayBrowser/#/R-GGA-8874078 PTK2 autophosphorylates IEA Gallus gallus A0A1D5PAR6 R-GGA-8874079 https://reactome.org/PathwayBrowser/#/R-GGA-8874079 PTK2 binds activated MET IEA Gallus gallus A0A1D5PAR6 R-GGA-8874080 https://reactome.org/PathwayBrowser/#/R-GGA-8874080 SRC phosphorylates PTK2 IEA Gallus gallus A0A1D5PAR6 R-GGA-8874082 https://reactome.org/PathwayBrowser/#/R-GGA-8874082 MET phosphorylates PTK2 IEA Gallus gallus A0A1D5PAR6 R-GGA-8874083 https://reactome.org/PathwayBrowser/#/R-GGA-8874083 p-Y397-PTK2 binds SRC IEA Gallus gallus A0A1D5PAR6 R-GGA-8874685 https://reactome.org/PathwayBrowser/#/R-GGA-8874685 CBL binds MET IEA Gallus gallus A0A1D5PAR6 R-GGA-8875183 https://reactome.org/PathwayBrowser/#/R-GGA-8875183 CBL monoubiquitinates activated MET IEA Gallus gallus A0A1D5PAR6 R-GGA-8875451 https://reactome.org/PathwayBrowser/#/R-GGA-8875451 MET phosphorylates CBL IEA Gallus gallus A0A1D5PAR6 R-GGA-8875482 https://reactome.org/PathwayBrowser/#/R-GGA-8875482 CBL recruits CIN85:endophilin to ubiquitinated MET IEA Gallus gallus A0A1D5PAR6 R-GGA-8875490 https://reactome.org/PathwayBrowser/#/R-GGA-8875490 EPS15 and HGS bind ubiquitinated MET IEA Gallus gallus A0A1D5PAR6 R-GGA-8875523 https://reactome.org/PathwayBrowser/#/R-GGA-8875523 MET binds TNS3 IEA Gallus gallus A0A1D5PAR6 R-GGA-8875531 https://reactome.org/PathwayBrowser/#/R-GGA-8875531 MET binds TNS4 IEA Gallus gallus A0A1D5PAR6 R-GGA-8875540 https://reactome.org/PathwayBrowser/#/R-GGA-8875540 GAB1 recruits CRK,CRKL to MET IEA Gallus gallus A0A1D5PAR6 R-GGA-8875558 https://reactome.org/PathwayBrowser/#/R-GGA-8875558 RAPGEF1 binds CRK,CRKL IEA Gallus gallus A0A1D5PAR6 R-GGA-8875568 https://reactome.org/PathwayBrowser/#/R-GGA-8875568 RAPGEF1 activates RAP1 IEA Gallus gallus A0A1D5PAR6 R-GGA-8875576 https://reactome.org/PathwayBrowser/#/R-GGA-8875576 CRK,CRKL recruits RAC1 GEF to activated MET IEA Gallus gallus A0A1D5PAR6 R-GGA-8875591 https://reactome.org/PathwayBrowser/#/R-GGA-8875591 DOCK7 activates RAC1 IEA Gallus gallus A0A1D5PAR6 R-GGA-8875659 https://reactome.org/PathwayBrowser/#/R-GGA-8875659 RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane IEA Gallus gallus A0A1D5PAR6 R-GGA-8875661 https://reactome.org/PathwayBrowser/#/R-GGA-8875661 GGA3 associates with activated MET receptor IEA Gallus gallus A0A1D5PAR6 R-GGA-8875816 https://reactome.org/PathwayBrowser/#/R-GGA-8875816 STAT3 binds activated MET receptor IEA Gallus gallus A0A1D5PAR6 R-GGA-8875817 https://reactome.org/PathwayBrowser/#/R-GGA-8875817 MET phosphorylates STAT3 IEA Gallus gallus A0A1D5PAR6 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus A0A1D5PAS5 R-GGA-376419 https://reactome.org/PathwayBrowser/#/R-GGA-376419 Formation of NR-MED1 Coactivator Complex IEA Gallus gallus A0A1D5PAS5 R-GGA-382096 https://reactome.org/PathwayBrowser/#/R-GGA-382096 Formation of NR-NCOR Corepressor Complex IEA Gallus gallus A0A1D5PAS6 R-GGA-9913339 https://reactome.org/PathwayBrowser/#/R-GGA-9913339 Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC IEA Gallus gallus A0A1D5PAT5 R-GGA-8938217 https://reactome.org/PathwayBrowser/#/R-GGA-8938217 RUNX1 binds the SWI/SNF complex IEA Gallus gallus A0A1D5PAT5 R-GGA-9932437 https://reactome.org/PathwayBrowser/#/R-GGA-9932437 ARID1 binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1 IEA Gallus gallus A0A1D5PAT5 R-GGA-9932447 https://reactome.org/PathwayBrowser/#/R-GGA-9932447 SMARCE1 and SMARCB1 bind SMARCC1 dimer:SMARCD1 IEA Gallus gallus A0A1D5PAT5 R-GGA-9932448 https://reactome.org/PathwayBrowser/#/R-GGA-9932448 SMARCC binds SMARCD IEA Gallus gallus A0A1D5PAT5 R-GGA-9932449 https://reactome.org/PathwayBrowser/#/R-GGA-9932449 SMARCE1 and SMARCB1 bind SMARCC dimer:SMARCDs IEA Gallus gallus A0A1D5PAT5 R-GGA-9932450 https://reactome.org/PathwayBrowser/#/R-GGA-9932450 SMARCD1 binds SMARCC1 homodimer IEA Gallus gallus A0A1D5PAT5 R-GGA-9932832 https://reactome.org/PathwayBrowser/#/R-GGA-9932832 BRD7 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2 IEA Gallus gallus A0A1D5PAT5 R-GGA-9932843 https://reactome.org/PathwayBrowser/#/R-GGA-9932843 PHF10 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD7 IEA Gallus gallus A0A1D5PAT5 R-GGA-9933236 https://reactome.org/PathwayBrowser/#/R-GGA-9933236 SS18-containing ATPase complex binds SMARCC dimer:SMARCDs:BICRAs:BRD9 IEA Gallus gallus A0A1D5PAT5 R-GGA-9933237 https://reactome.org/PathwayBrowser/#/R-GGA-9933237 PBRM1-containing ATPase complex binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD&:PHF10 IEA Gallus gallus A0A1D5PAT5 R-GGA-9933238 https://reactome.org/PathwayBrowser/#/R-GGA-9933238 SS18-containing ATPase complex binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1:DPF1,2,3 IEA Gallus gallus A0A1D5PAT5 R-GGA-9934021 https://reactome.org/PathwayBrowser/#/R-GGA-9934021 Formation of neuronal progenitor BAF (npBAF) IEA Gallus gallus A0A1D5PAT5 R-GGA-9934022 https://reactome.org/PathwayBrowser/#/R-GGA-9934022 DPF2, PHF10 bind SMARCC1:SMARCC2 dimer:SMARD1:ARID1A IEA Gallus gallus A0A1D5PAT5 R-GGA-9934024 https://reactome.org/PathwayBrowser/#/R-GGA-9934024 SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10 IEA Gallus gallus A0A1D5PAT5 R-GGA-9934026 https://reactome.org/PathwayBrowser/#/R-GGA-9934026 SMARCE1 and SMARCB1 bind SMARCC1:SMARCC2 dimer:SMARCD1 IEA Gallus gallus A0A1D5PAT5 R-GGA-9934027 https://reactome.org/PathwayBrowser/#/R-GGA-9934027 SMARCC1 and SMARCC2 bind SMARCD1 IEA Gallus gallus A0A1D5PAU6 R-GGA-9860273 https://reactome.org/PathwayBrowser/#/R-GGA-9860273 Dimerization of p-S446-IRF5 IEA Gallus gallus A0A1D5PAU6 R-GGA-9860278 https://reactome.org/PathwayBrowser/#/R-GGA-9860278 p-S446-IRF5 dimer translocates to the nucleus IEA Gallus gallus A0A1D5PAU6 R-GGA-9860290 https://reactome.org/PathwayBrowser/#/R-GGA-9860290 TASL recruits IRF5 IEA Gallus gallus A0A1D5PAU7 R-GGA-5433074 https://reactome.org/PathwayBrowser/#/R-GGA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Gallus gallus A0A1D5PAU7 R-GGA-9753944 https://reactome.org/PathwayBrowser/#/R-GGA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Gallus gallus A0A1D5PAY3 R-GGA-3295579 https://reactome.org/PathwayBrowser/#/R-GGA-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Gallus gallus A0A1D5PAZ6 R-GGA-375384 https://reactome.org/PathwayBrowser/#/R-GGA-375384 Bombesin-like receptors bind bombesin homologues IEA Gallus gallus A0A1D5PAZ6 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1D5PAZ6 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1D5PAZ6 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1D5PAZ7 R-GGA-2022399 https://reactome.org/PathwayBrowser/#/R-GGA-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Gallus gallus A0A1D5PB14 R-GGA-201475 https://reactome.org/PathwayBrowser/#/R-GGA-201475 I-Smad competes with R-Smad1/5/8 for type I receptor IEA Gallus gallus A0A1D5PB14 R-GGA-201821 https://reactome.org/PathwayBrowser/#/R-GGA-201821 I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated IEA Gallus gallus A0A1D5PB14 R-GGA-202626 https://reactome.org/PathwayBrowser/#/R-GGA-202626 I-Smad competes with Co-Smad for R-Smad1/5/8 IEA Gallus gallus A0A1D5PB24 R-GGA-4641205 https://reactome.org/PathwayBrowser/#/R-GGA-4641205 RSPO:LGR binds ZNRF3 IEA Gallus gallus A0A1D5PB24 R-GGA-4641206 https://reactome.org/PathwayBrowser/#/R-GGA-4641206 RSPOs bind LGRs IEA Gallus gallus A0A1D5PB24 R-GGA-4641246 https://reactome.org/PathwayBrowser/#/R-GGA-4641246 ZNRF3 autoubiquitinates to promote its internalization IEA Gallus gallus A0A1D5PB37 R-GGA-5577050 https://reactome.org/PathwayBrowser/#/R-GGA-5577050 AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region IEA Gallus gallus A0A1D5PB37 R-GGA-5577237 https://reactome.org/PathwayBrowser/#/R-GGA-5577237 KCNH2:KCNE transport K+ from cytosol to extracellular region IEA Gallus gallus A0A1D5PB37 R-GGA-9613264 https://reactome.org/PathwayBrowser/#/R-GGA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Gallus gallus A0A1D5PB61 R-GGA-350604 https://reactome.org/PathwayBrowser/#/R-GGA-350604 Agmatine + H2O <=> putrescine + urea IEA Gallus gallus A0A1D5PB68 R-GGA-72103 https://reactome.org/PathwayBrowser/#/R-GGA-72103 Formation of pre-mRNPs IEA Gallus gallus A0A1D5PB68 R-GGA-9018778 https://reactome.org/PathwayBrowser/#/R-GGA-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Gallus gallus A0A1D5PB68 R-GGA-9018787 https://reactome.org/PathwayBrowser/#/R-GGA-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Gallus gallus A0A1D5PB68 R-GGA-9696266 https://reactome.org/PathwayBrowser/#/R-GGA-9696266 RND2 binds effectors IEA Gallus gallus A0A1D5PB68 R-GGA-9696268 https://reactome.org/PathwayBrowser/#/R-GGA-9696268 RND3 binds effectors IEA Gallus gallus A0A1D5PB68 R-GGA-9696271 https://reactome.org/PathwayBrowser/#/R-GGA-9696271 RND1 binds effectors IEA Gallus gallus A0A1D5PB68 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5PB71 R-GGA-141423 https://reactome.org/PathwayBrowser/#/R-GGA-141423 Binding of the MCC complex to the APC/C complex IEA Gallus gallus A0A1D5PB71 R-GGA-174057 https://reactome.org/PathwayBrowser/#/R-GGA-174057 Multiubiquitination of APC/C-associated Cdh1 IEA Gallus gallus A0A1D5PB71 R-GGA-174058 https://reactome.org/PathwayBrowser/#/R-GGA-174058 Degradation of multiubiquitinated Cdh1 IEA Gallus gallus A0A1D5PB71 R-GGA-174070 https://reactome.org/PathwayBrowser/#/R-GGA-174070 Association of Cdh1 with the APC/C IEA Gallus gallus A0A1D5PB71 R-GGA-174079 https://reactome.org/PathwayBrowser/#/R-GGA-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Gallus gallus A0A1D5PB71 R-GGA-174088 https://reactome.org/PathwayBrowser/#/R-GGA-174088 Association of cell cycle proteins with the APC/C:Cdh1 complex IEA Gallus gallus A0A1D5PB71 R-GGA-174104 https://reactome.org/PathwayBrowser/#/R-GGA-174104 Ubiquitination of Cyclin A by APC/C:Cdc20 complex IEA Gallus gallus A0A1D5PB71 R-GGA-174105 https://reactome.org/PathwayBrowser/#/R-GGA-174105 Degradation of multiubiquitinated cell cycle proteins IEA Gallus gallus A0A1D5PB71 R-GGA-174119 https://reactome.org/PathwayBrowser/#/R-GGA-174119 Free APC/C phosphorylated by Plk1 IEA Gallus gallus A0A1D5PB71 R-GGA-174121 https://reactome.org/PathwayBrowser/#/R-GGA-174121 Association of Securin with Cdc20:APC/C complex IEA Gallus gallus A0A1D5PB71 R-GGA-174139 https://reactome.org/PathwayBrowser/#/R-GGA-174139 Dissociation of phospho-Cdh1 from the APC/C complex IEA Gallus gallus A0A1D5PB71 R-GGA-174144 https://reactome.org/PathwayBrowser/#/R-GGA-174144 Ubiquitination of Securin by phospho-APC/C:Cdc20 complex IEA Gallus gallus A0A1D5PB71 R-GGA-174157 https://reactome.org/PathwayBrowser/#/R-GGA-174157 Degradation of multiubiquitinated Cyclin B IEA Gallus gallus A0A1D5PB71 R-GGA-174171 https://reactome.org/PathwayBrowser/#/R-GGA-174171 Association of Cyclin A with the APC/C IEA Gallus gallus A0A1D5PB71 R-GGA-174195 https://reactome.org/PathwayBrowser/#/R-GGA-174195 Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex IEA Gallus gallus A0A1D5PB71 R-GGA-174202 https://reactome.org/PathwayBrowser/#/R-GGA-174202 Degradation of multiubiquitinated Securin IEA Gallus gallus A0A1D5PB71 R-GGA-174224 https://reactome.org/PathwayBrowser/#/R-GGA-174224 Dissociation of Cdc20 from APC/C complex IEA Gallus gallus A0A1D5PB71 R-GGA-174227 https://reactome.org/PathwayBrowser/#/R-GGA-174227 Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex IEA Gallus gallus A0A1D5PB71 R-GGA-174238 https://reactome.org/PathwayBrowser/#/R-GGA-174238 Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 IEA Gallus gallus A0A1D5PB71 R-GGA-174255 https://reactome.org/PathwayBrowser/#/R-GGA-174255 Degradation multiubiquitinated Cyclin A IEA Gallus gallus A0A1D5PB71 R-GGA-179410 https://reactome.org/PathwayBrowser/#/R-GGA-179410 Association of Nek2A with MCC:APC/C IEA Gallus gallus A0A1D5PB71 R-GGA-179417 https://reactome.org/PathwayBrowser/#/R-GGA-179417 Multiubiquitination of Nek2A IEA Gallus gallus A0A1D5PB71 R-GGA-179421 https://reactome.org/PathwayBrowser/#/R-GGA-179421 Degradation of multiubiquitinated Nek2A IEA Gallus gallus A0A1D5PB71 R-GGA-188191 https://reactome.org/PathwayBrowser/#/R-GGA-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Gallus gallus A0A1D5PB71 R-GGA-188371 https://reactome.org/PathwayBrowser/#/R-GGA-188371 Association of Cyclin A:Cdk2 with Cdh1 IEA Gallus gallus A0A1D5PB71 R-GGA-3788705 https://reactome.org/PathwayBrowser/#/R-GGA-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Gallus gallus A0A1D5PB71 R-GGA-3788708 https://reactome.org/PathwayBrowser/#/R-GGA-3788708 CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 IEA Gallus gallus A0A1D5PB71 R-GGA-3788724 https://reactome.org/PathwayBrowser/#/R-GGA-3788724 Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 IEA Gallus gallus A0A1D5PB71 R-GGA-68712 https://reactome.org/PathwayBrowser/#/R-GGA-68712 The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 IEA Gallus gallus A0A1D5PB71 R-GGA-69015 https://reactome.org/PathwayBrowser/#/R-GGA-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Gallus gallus A0A1D5PB71 R-GGA-9686969 https://reactome.org/PathwayBrowser/#/R-GGA-9686969 APC/C:Cdh1 polyubiquitinates SKP2 IEA Gallus gallus A0A1D5PB71 R-GGA-9686980 https://reactome.org/PathwayBrowser/#/R-GGA-9686980 RB1 recruits APC/C:Cdh1 complex to SKP2 IEA Gallus gallus A0A1D5PB71 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PB71 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PB71 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PB71 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PB77 R-GGA-159431 https://reactome.org/PathwayBrowser/#/R-GGA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Gallus gallus A0A1D5PB77 R-GGA-192312 https://reactome.org/PathwayBrowser/#/R-GGA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Gallus gallus A0A1D5PB77 R-GGA-193491 https://reactome.org/PathwayBrowser/#/R-GGA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Gallus gallus A0A1D5PB77 R-GGA-9033235 https://reactome.org/PathwayBrowser/#/R-GGA-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1D5PB77 R-GGA-9033236 https://reactome.org/PathwayBrowser/#/R-GGA-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Gallus gallus A0A1D5PBA8 R-GGA-8850777 https://reactome.org/PathwayBrowser/#/R-GGA-8850777 SPINK6 binds KLK14 IEA Gallus gallus A0A1D5PBA8 R-GGA-8850797 https://reactome.org/PathwayBrowser/#/R-GGA-8850797 SPINK6 binds KLK13 IEA Gallus gallus A0A1D5PBD8 R-GGA-111439 https://reactome.org/PathwayBrowser/#/R-GGA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Gallus gallus A0A1D5PBD8 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A1D5PBD8 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A1D5PBD8 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A1D5PBD8 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A1D5PBD8 R-GGA-158441 https://reactome.org/PathwayBrowser/#/R-GGA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PBD8 R-GGA-158447 https://reactome.org/PathwayBrowser/#/R-GGA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Gallus gallus A0A1D5PBD8 R-GGA-158481 https://reactome.org/PathwayBrowser/#/R-GGA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PBD8 R-GGA-158484 https://reactome.org/PathwayBrowser/#/R-GGA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Gallus gallus A0A1D5PBD8 R-GGA-159046 https://reactome.org/PathwayBrowser/#/R-GGA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Gallus gallus A0A1D5PBD8 R-GGA-159050 https://reactome.org/PathwayBrowser/#/R-GGA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Gallus gallus A0A1D5PBD8 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5PBD8 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5PBD8 R-GGA-170825 https://reactome.org/PathwayBrowser/#/R-GGA-170825 NPC exports GCK1 from nucleus IEA Gallus gallus A0A1D5PBD8 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1D5PBD8 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5PBD8 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5PBD8 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5PBD8 R-GGA-2990880 https://reactome.org/PathwayBrowser/#/R-GGA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Gallus gallus A0A1D5PBD8 R-GGA-2990882 https://reactome.org/PathwayBrowser/#/R-GGA-2990882 CDK1 phosphorylates NUP98 IEA Gallus gallus A0A1D5PBD8 R-GGA-4551649 https://reactome.org/PathwayBrowser/#/R-GGA-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Gallus gallus A0A1D5PBD8 R-GGA-4551679 https://reactome.org/PathwayBrowser/#/R-GGA-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Gallus gallus A0A1D5PBD8 R-GGA-4615872 https://reactome.org/PathwayBrowser/#/R-GGA-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Gallus gallus A0A1D5PBD8 R-GGA-4615987 https://reactome.org/PathwayBrowser/#/R-GGA-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Gallus gallus A0A1D5PBD8 R-GGA-4655355 https://reactome.org/PathwayBrowser/#/R-GGA-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Gallus gallus A0A1D5PBD8 R-GGA-5228523 https://reactome.org/PathwayBrowser/#/R-GGA-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Gallus gallus A0A1D5PBD8 R-GGA-5578744 https://reactome.org/PathwayBrowser/#/R-GGA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Gallus gallus A0A1D5PBD8 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A1D5PBD8 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1D5PBD8 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1D5PBD8 R-GGA-77587 https://reactome.org/PathwayBrowser/#/R-GGA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Gallus gallus A0A1D5PBD8 R-GGA-9615901 https://reactome.org/PathwayBrowser/#/R-GGA-9615901 AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex IEA Gallus gallus A0A1D5PBD8 R-GGA-9618378 https://reactome.org/PathwayBrowser/#/R-GGA-9618378 POM121 binds the Nup107-Nup160 complex IEA Gallus gallus A0A1D5PBD8 R-GGA-9634169 https://reactome.org/PathwayBrowser/#/R-GGA-9634169 POM121 and NDC1 bind the Nup93 complex IEA Gallus gallus A0A1D5PBD8 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1D5PBE3 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus A0A1D5PBE3 R-GGA-9865630 https://reactome.org/PathwayBrowser/#/R-GGA-9865630 Metallochaperone inserts 2Cu2+ into MT-CO2 IEA Gallus gallus A0A1D5PBH1 R-GGA-8937369 https://reactome.org/PathwayBrowser/#/R-GGA-8937369 ATAD2 binds ESR1 IEA Gallus gallus A0A1D5PBH3 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus A0A1D5PBH8 R-GGA-204779 https://reactome.org/PathwayBrowser/#/R-GGA-204779 Interaction of Tie2 with Ang1 IEA Gallus gallus A0A1D5PBH8 R-GGA-204798 https://reactome.org/PathwayBrowser/#/R-GGA-204798 Interaction of Tie2 and p85 of PI3K IEA Gallus gallus A0A1D5PBH8 R-GGA-204813 https://reactome.org/PathwayBrowser/#/R-GGA-204813 Interaction of Tie2 and Grb14 IEA Gallus gallus A0A1D5PBH8 R-GGA-204850 https://reactome.org/PathwayBrowser/#/R-GGA-204850 Interaction of Tie2 and Dok-2 IEA Gallus gallus A0A1D5PBH8 R-GGA-204861 https://reactome.org/PathwayBrowser/#/R-GGA-204861 Interaction of Tie2 and Shc1 IEA Gallus gallus A0A1D5PBH8 R-GGA-204871 https://reactome.org/PathwayBrowser/#/R-GGA-204871 Interaction of Tie2 and Grb2 IEA Gallus gallus A0A1D5PBH8 R-GGA-204873 https://reactome.org/PathwayBrowser/#/R-GGA-204873 Interaction of Tie2 and Shp2 IEA Gallus gallus A0A1D5PBH8 R-GGA-210881 https://reactome.org/PathwayBrowser/#/R-GGA-210881 Dimerization of Tie2/Ang1 complex IEA Gallus gallus A0A1D5PBH8 R-GGA-210974 https://reactome.org/PathwayBrowser/#/R-GGA-210974 Interaction of SOS-1 to Tie2 bound Grb2 IEA Gallus gallus A0A1D5PBH8 R-GGA-210977 https://reactome.org/PathwayBrowser/#/R-GGA-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Gallus gallus A0A1D5PBH8 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5PBI5 R-GGA-5652005 https://reactome.org/PathwayBrowser/#/R-GGA-5652005 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA IEA Gallus gallus A0A1D5PBI5 R-GGA-5652009 https://reactome.org/PathwayBrowser/#/R-GGA-5652009 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA IEA Gallus gallus A0A1D5PBI5 R-GGA-5689317 https://reactome.org/PathwayBrowser/#/R-GGA-5689317 Formation of the pre-incision complex in GG-NER IEA Gallus gallus A0A1D5PBI5 R-GGA-5689861 https://reactome.org/PathwayBrowser/#/R-GGA-5689861 Recruitment of XPA and release of CAK IEA Gallus gallus A0A1D5PBI5 R-GGA-5690213 https://reactome.org/PathwayBrowser/#/R-GGA-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Gallus gallus A0A1D5PBI5 R-GGA-5690990 https://reactome.org/PathwayBrowser/#/R-GGA-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Gallus gallus A0A1D5PBI5 R-GGA-5690996 https://reactome.org/PathwayBrowser/#/R-GGA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Gallus gallus A0A1D5PBI5 R-GGA-5691000 https://reactome.org/PathwayBrowser/#/R-GGA-5691000 TFIIH binds GG-NER site to form a verification complex IEA Gallus gallus A0A1D5PBI5 R-GGA-5691006 https://reactome.org/PathwayBrowser/#/R-GGA-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Gallus gallus A0A1D5PBI5 R-GGA-5696655 https://reactome.org/PathwayBrowser/#/R-GGA-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Gallus gallus A0A1D5PBI5 R-GGA-5696664 https://reactome.org/PathwayBrowser/#/R-GGA-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Gallus gallus A0A1D5PBI5 R-GGA-5696670 https://reactome.org/PathwayBrowser/#/R-GGA-5696670 CHD1L is recruited to GG-NER site IEA Gallus gallus A0A1D5PBI5 R-GGA-6781833 https://reactome.org/PathwayBrowser/#/R-GGA-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Gallus gallus A0A1D5PBI5 R-GGA-6781867 https://reactome.org/PathwayBrowser/#/R-GGA-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Gallus gallus A0A1D5PBI5 R-GGA-6782069 https://reactome.org/PathwayBrowser/#/R-GGA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Gallus gallus A0A1D5PBI5 R-GGA-6782131 https://reactome.org/PathwayBrowser/#/R-GGA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5PBI5 R-GGA-6782138 https://reactome.org/PathwayBrowser/#/R-GGA-6782138 ERCC5 and RPA bind TC-NER site IEA Gallus gallus A0A1D5PBI5 R-GGA-6782204 https://reactome.org/PathwayBrowser/#/R-GGA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Gallus gallus A0A1D5PBI5 R-GGA-6782208 https://reactome.org/PathwayBrowser/#/R-GGA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Gallus gallus A0A1D5PBI5 R-GGA-6782211 https://reactome.org/PathwayBrowser/#/R-GGA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Gallus gallus A0A1D5PBI5 R-GGA-6782227 https://reactome.org/PathwayBrowser/#/R-GGA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Gallus gallus A0A1D5PBI5 R-GGA-6782943 https://reactome.org/PathwayBrowser/#/R-GGA-6782943 UV-DDB ubiquitinates XPC IEA Gallus gallus A0A1D5PBI5 R-GGA-6790454 https://reactome.org/PathwayBrowser/#/R-GGA-6790454 SUMOylation of XPC IEA Gallus gallus A0A1D5PBI5 R-GGA-6790487 https://reactome.org/PathwayBrowser/#/R-GGA-6790487 RNF111 ubiquitinates SUMOylated XPC IEA Gallus gallus A0A1D5PBI5 R-GGA-8952638 https://reactome.org/PathwayBrowser/#/R-GGA-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PBI5 R-GGA-8952639 https://reactome.org/PathwayBrowser/#/R-GGA-8952639 NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PBI5 R-GGA-8955245 https://reactome.org/PathwayBrowser/#/R-GGA-8955245 CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus IEA Gallus gallus A0A1D5PBI5 R-GGA-8956045 https://reactome.org/PathwayBrowser/#/R-GGA-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PBI5 R-GGA-9684118 https://reactome.org/PathwayBrowser/#/R-GGA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5PBJ1 R-GGA-917805 https://reactome.org/PathwayBrowser/#/R-GGA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Gallus gallus A0A1D5PBJ5 R-GGA-9609921 https://reactome.org/PathwayBrowser/#/R-GGA-9609921 SGTA binds Tail-anchored protein IEA Gallus gallus A0A1D5PBJ5 R-GGA-9617595 https://reactome.org/PathwayBrowser/#/R-GGA-9617595 SGTA binds mislocalized membrane protein IEA Gallus gallus A0A1D5PBK0 R-GGA-8952618 https://reactome.org/PathwayBrowser/#/R-GGA-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PBK0 R-GGA-8952620 https://reactome.org/PathwayBrowser/#/R-GGA-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PBK0 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5PBK0 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5PBK0 R-GGA-8956200 https://reactome.org/PathwayBrowser/#/R-GGA-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PBK0 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PBK0 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PBK0 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PBK0 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PBK8 R-GGA-1482612 https://reactome.org/PathwayBrowser/#/R-GGA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Gallus gallus A0A1D5PBK8 R-GGA-1482685 https://reactome.org/PathwayBrowser/#/R-GGA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Gallus gallus A0A1D5PBK8 R-GGA-1482745 https://reactome.org/PathwayBrowser/#/R-GGA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Gallus gallus A0A1D5PBK8 R-GGA-1482771 https://reactome.org/PathwayBrowser/#/R-GGA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Gallus gallus A0A1D5PBK8 R-GGA-1482825 https://reactome.org/PathwayBrowser/#/R-GGA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Gallus gallus A0A1D5PBK8 R-GGA-1482828 https://reactome.org/PathwayBrowser/#/R-GGA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Gallus gallus A0A1D5PBK8 R-GGA-1482847 https://reactome.org/PathwayBrowser/#/R-GGA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Gallus gallus A0A1D5PBK8 R-GGA-1482856 https://reactome.org/PathwayBrowser/#/R-GGA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Gallus gallus A0A1D5PBK8 R-GGA-1482862 https://reactome.org/PathwayBrowser/#/R-GGA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Gallus gallus A0A1D5PBK8 R-GGA-1482884 https://reactome.org/PathwayBrowser/#/R-GGA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Gallus gallus A0A1D5PBK8 R-GGA-1482897 https://reactome.org/PathwayBrowser/#/R-GGA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Gallus gallus A0A1D5PBK8 R-GGA-1482920 https://reactome.org/PathwayBrowser/#/R-GGA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Gallus gallus A0A1D5PBM1 R-GGA-425577 https://reactome.org/PathwayBrowser/#/R-GGA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Gallus gallus A0A1D5PBN0 R-GGA-1454916 https://reactome.org/PathwayBrowser/#/R-GGA-1454916 The ABCC family mediates organic anion transport IEA Gallus gallus A0A1D5PBN0 R-GGA-383190 https://reactome.org/PathwayBrowser/#/R-GGA-383190 HCO3- transport through ion channel IEA Gallus gallus A0A1D5PBN0 R-GGA-5627071 https://reactome.org/PathwayBrowser/#/R-GGA-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane IEA Gallus gallus A0A1D5PBN0 R-GGA-5627072 https://reactome.org/PathwayBrowser/#/R-GGA-5627072 RHOQ binds GOPC:CFTR IEA Gallus gallus A0A1D5PBN0 R-GGA-5627275 https://reactome.org/PathwayBrowser/#/R-GGA-5627275 GOPC promotes translocation of CFTR to lysosomes IEA Gallus gallus A0A1D5PBN0 R-GGA-5678863 https://reactome.org/PathwayBrowser/#/R-GGA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Gallus gallus A0A1D5PBN0 R-GGA-6782106 https://reactome.org/PathwayBrowser/#/R-GGA-6782106 USP10 deubiquitinates SNX3, CFTR IEA Gallus gallus A0A1D5PBN0 R-GGA-8866277 https://reactome.org/PathwayBrowser/#/R-GGA-8866277 AP-2 directly binds some endocytic cargo IEA Gallus gallus A0A1D5PBN0 R-GGA-8866542 https://reactome.org/PathwayBrowser/#/R-GGA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Gallus gallus A0A1D5PBN0 R-GGA-8866546 https://reactome.org/PathwayBrowser/#/R-GGA-8866546 RNF5 and RNF185 ubiquitinate misfolded CFTR IEA Gallus gallus A0A1D5PBN0 R-GGA-8866551 https://reactome.org/PathwayBrowser/#/R-GGA-8866551 CFTR binds components of the ERAD machinery for ubiquitination and degradation IEA Gallus gallus A0A1D5PBN0 R-GGA-8866553 https://reactome.org/PathwayBrowser/#/R-GGA-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Gallus gallus A0A1D5PBN0 R-GGA-8866851 https://reactome.org/PathwayBrowser/#/R-GGA-8866851 CFTR transits to the plasma membrane IEA Gallus gallus A0A1D5PBN0 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5PBN0 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5PBN0 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5PBN0 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5PBN0 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5PBN0 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5PBN0 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5PBN0 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5PBN0 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PBN0 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PBN0 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5PBN0 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5PBN0 R-GGA-9641111 https://reactome.org/PathwayBrowser/#/R-GGA-9641111 Parkin transfers Ub to misfolded proteins IEA Gallus gallus A0A1D5PBN0 R-GGA-9641127 https://reactome.org/PathwayBrowser/#/R-GGA-9641127 Ub:misfolded proteins polymerize to PolyUb:misfolded proteins IEA Gallus gallus A0A1D5PBN0 R-GGA-9646679 https://reactome.org/PathwayBrowser/#/R-GGA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Gallus gallus A0A1D5PBN7 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5PBN7 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5PBN7 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5PBN7 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5PBN7 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5PBP6 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5PBP6 R-GGA-904830 https://reactome.org/PathwayBrowser/#/R-GGA-904830 SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region IEA Gallus gallus A0A1D5PBP6 R-GGA-917891 https://reactome.org/PathwayBrowser/#/R-GGA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Gallus gallus A0A1D5PBR4 R-GGA-5626938 https://reactome.org/PathwayBrowser/#/R-GGA-5626938 Beta-catenin binds SOX proteins IEA Gallus gallus A0A1D5PBR4 R-GGA-5665608 https://reactome.org/PathwayBrowser/#/R-GGA-5665608 TCF:Beta-catenin binds SOX proteins IEA Gallus gallus A0A1D5PBR8 R-GGA-8955010 https://reactome.org/PathwayBrowser/#/R-GGA-8955010 LRTOMT transfers Met to DA, forming 3MT IEA Gallus gallus A0A1D5PBS4 R-GGA-1236943 https://reactome.org/PathwayBrowser/#/R-GGA-1236943 Loading of antigen peptide onto MHC class I molecule IEA Gallus gallus A0A1D5PBS4 R-GGA-1236954 https://reactome.org/PathwayBrowser/#/R-GGA-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Gallus gallus A0A1D5PBS4 R-GGA-1236964 https://reactome.org/PathwayBrowser/#/R-GGA-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Gallus gallus A0A1D5PBS4 R-GGA-1236965 https://reactome.org/PathwayBrowser/#/R-GGA-1236965 Export of peptide loaded MHC class I complex to PM IEA Gallus gallus A0A1D5PBS4 R-GGA-198955 https://reactome.org/PathwayBrowser/#/R-GGA-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Gallus gallus A0A1D5PBS4 R-GGA-199062 https://reactome.org/PathwayBrowser/#/R-GGA-199062 KLRC1:KLRD1 heterodimer interacts with HLA-E IEA Gallus gallus A0A1D5PBS4 R-GGA-210289 https://reactome.org/PathwayBrowser/#/R-GGA-210289 Recruitment of SYK to p-DAP12 IEA Gallus gallus A0A1D5PBS4 R-GGA-2395412 https://reactome.org/PathwayBrowser/#/R-GGA-2395412 Phosphorylation of SYK IEA Gallus gallus A0A1D5PBS4 R-GGA-2396594 https://reactome.org/PathwayBrowser/#/R-GGA-2396594 Phosphorylation of SLP-76 by p-SYK IEA Gallus gallus A0A1D5PBS4 R-GGA-2424480 https://reactome.org/PathwayBrowser/#/R-GGA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PBS4 R-GGA-2424482 https://reactome.org/PathwayBrowser/#/R-GGA-2424482 p85 regulatory unit of PI3K binds p-6Y-SYK IEA Gallus gallus A0A1D5PBS4 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus A0A1D5PBS4 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus A0A1D5PBS4 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus A0A1D5PBS4 R-GGA-5691154 https://reactome.org/PathwayBrowser/#/R-GGA-5691154 HFE binds TFRC dimer IEA Gallus gallus A0A1D5PBS4 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5PBS4 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PBS4 R-GGA-8863973 https://reactome.org/PathwayBrowser/#/R-GGA-8863973 Fusion of ERC and phagosome IEA Gallus gallus A0A1D5PBS4 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus A0A1D5PBS4 R-GGA-8951499 https://reactome.org/PathwayBrowser/#/R-GGA-8951499 Loading of antigenic peptides on to class I MHC IEA Gallus gallus A0A1D5PBS4 R-GGA-983138 https://reactome.org/PathwayBrowser/#/R-GGA-983138 Transport of MHC heterotrimer to ER exit site IEA Gallus gallus A0A1D5PBS4 R-GGA-983145 https://reactome.org/PathwayBrowser/#/R-GGA-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Gallus gallus A0A1D5PBS4 R-GGA-983146 https://reactome.org/PathwayBrowser/#/R-GGA-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Gallus gallus A0A1D5PBS4 R-GGA-983421 https://reactome.org/PathwayBrowser/#/R-GGA-983421 Journey of cargo through Golgi complex IEA Gallus gallus A0A1D5PBS4 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus A0A1D5PBS4 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus A0A1D5PBS4 R-GGA-983425 https://reactome.org/PathwayBrowser/#/R-GGA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Gallus gallus A0A1D5PBS4 R-GGA-983427 https://reactome.org/PathwayBrowser/#/R-GGA-983427 Expression of peptide bound class I MHC on cell surface IEA Gallus gallus A0A1D5PBS6 R-GGA-448661 https://reactome.org/PathwayBrowser/#/R-GGA-448661 IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 IEA Gallus gallus A0A1D5PBS6 R-GGA-449811 https://reactome.org/PathwayBrowser/#/R-GGA-449811 IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 IEA Gallus gallus A0A1D5PBS6 R-GGA-6784006 https://reactome.org/PathwayBrowser/#/R-GGA-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Gallus gallus A0A1D5PBS6 R-GGA-6784319 https://reactome.org/PathwayBrowser/#/R-GGA-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Gallus gallus A0A1D5PBS6 R-GGA-6784323 https://reactome.org/PathwayBrowser/#/R-GGA-6784323 IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 IEA Gallus gallus A0A1D5PBS6 R-GGA-6784324 https://reactome.org/PathwayBrowser/#/R-GGA-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Gallus gallus A0A1D5PBS6 R-GGA-6784791 https://reactome.org/PathwayBrowser/#/R-GGA-6784791 p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 IEA Gallus gallus A0A1D5PBS6 R-GGA-8854645 https://reactome.org/PathwayBrowser/#/R-GGA-8854645 IL22:IL22RA1:JAK1 binds IL10RB:TYK2 IEA Gallus gallus A0A1D5PBS6 R-GGA-8986480 https://reactome.org/PathwayBrowser/#/R-GGA-8986480 IL26:IL20RA:JAK1 binds IL10RB:TYK2 IEA Gallus gallus A0A1D5PBS6 R-GGA-8986985 https://reactome.org/PathwayBrowser/#/R-GGA-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Gallus gallus A0A1D5PBS6 R-GGA-8986994 https://reactome.org/PathwayBrowser/#/R-GGA-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Gallus gallus A0A1D5PBS6 R-GGA-8986995 https://reactome.org/PathwayBrowser/#/R-GGA-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Gallus gallus A0A1D5PBS6 R-GGA-8987014 https://reactome.org/PathwayBrowser/#/R-GGA-8987014 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 IEA Gallus gallus A0A1D5PBS6 R-GGA-8987033 https://reactome.org/PathwayBrowser/#/R-GGA-8987033 p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 IEA Gallus gallus A0A1D5PBS6 R-GGA-8987040 https://reactome.org/PathwayBrowser/#/R-GGA-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Gallus gallus A0A1D5PBS6 R-GGA-8987042 https://reactome.org/PathwayBrowser/#/R-GGA-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Gallus gallus A0A1D5PBS6 R-GGA-8987070 https://reactome.org/PathwayBrowser/#/R-GGA-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Gallus gallus A0A1D5PBS6 R-GGA-8987080 https://reactome.org/PathwayBrowser/#/R-GGA-8987080 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 IEA Gallus gallus A0A1D5PBS6 R-GGA-8987105 https://reactome.org/PathwayBrowser/#/R-GGA-8987105 IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 IEA Gallus gallus A0A1D5PBS6 R-GGA-8987132 https://reactome.org/PathwayBrowser/#/R-GGA-8987132 IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11 IEA Gallus gallus A0A1D5PBS6 R-GGA-8987202 https://reactome.org/PathwayBrowser/#/R-GGA-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Gallus gallus A0A1D5PBS6 R-GGA-8987223 https://reactome.org/PathwayBrowser/#/R-GGA-8987223 IL10RB binds TYK2 IEA Gallus gallus A0A1D5PBS6 R-GGA-8987230 https://reactome.org/PathwayBrowser/#/R-GGA-8987230 p-STAT1 and p-STAT3 dissociates from IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 IEA Gallus gallus A0A1D5PBS6 R-GGA-8987236 https://reactome.org/PathwayBrowser/#/R-GGA-8987236 p-Y705-STAT3 dissociates from IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 IEA Gallus gallus A0A1D5PBS6 R-GGA-8987255 https://reactome.org/PathwayBrowser/#/R-GGA-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Gallus gallus A0A1D5PBS6 R-GGA-8987266 https://reactome.org/PathwayBrowser/#/R-GGA-8987266 IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 IEA Gallus gallus A0A1D5PBT4 R-GGA-163090 https://reactome.org/PathwayBrowser/#/R-GGA-163090 Elongation Of The Telomeric Chromosome End IEA Gallus gallus A0A1D5PBT4 R-GGA-163099 https://reactome.org/PathwayBrowser/#/R-GGA-163099 Alignment Of The RNA Template On The Telomeric Chromosome End IEA Gallus gallus A0A1D5PBT4 R-GGA-164617 https://reactome.org/PathwayBrowser/#/R-GGA-164617 Elongation of Extended Telomeric Chromosome End IEA Gallus gallus A0A1D5PBT4 R-GGA-164620 https://reactome.org/PathwayBrowser/#/R-GGA-164620 Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End IEA Gallus gallus A0A1D5PBT4 R-GGA-174425 https://reactome.org/PathwayBrowser/#/R-GGA-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Gallus gallus A0A1D5PBT4 R-GGA-174427 https://reactome.org/PathwayBrowser/#/R-GGA-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Gallus gallus A0A1D5PBT4 R-GGA-174439 https://reactome.org/PathwayBrowser/#/R-GGA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Gallus gallus A0A1D5PBT4 R-GGA-174452 https://reactome.org/PathwayBrowser/#/R-GGA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Gallus gallus A0A1D5PBU5 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A1D5PBU5 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A1D5PBU5 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A1D5PBU5 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A1D5PBU5 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5PBU5 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5PBU5 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5PBU5 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5PBU5 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5PBU5 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A1D5PBU5 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5PBU5 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5PBU5 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1D5PBU5 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus A0A1D5PBU5 R-GGA-990489 https://reactome.org/PathwayBrowser/#/R-GGA-990489 Kinesin-13 is a dimer IEA Gallus gallus A0A1D5PBV4 R-GGA-5362564 https://reactome.org/PathwayBrowser/#/R-GGA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Gallus gallus A0A1D5PBV4 R-GGA-71707 https://reactome.org/PathwayBrowser/#/R-GGA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Gallus gallus A0A1D5PBV6 R-GGA-390593 https://reactome.org/PathwayBrowser/#/R-GGA-390593 ATP Hydrolysis By Myosin IEA Gallus gallus A0A1D5PBV6 R-GGA-390595 https://reactome.org/PathwayBrowser/#/R-GGA-390595 Calcium Binds Troponin-C IEA Gallus gallus A0A1D5PBV6 R-GGA-390597 https://reactome.org/PathwayBrowser/#/R-GGA-390597 Release Of ADP From Myosin IEA Gallus gallus A0A1D5PBV6 R-GGA-390598 https://reactome.org/PathwayBrowser/#/R-GGA-390598 Myosin Binds ATP IEA Gallus gallus A0A1D5PBX2 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus A0A1D5PBX2 R-GGA-4090288 https://reactome.org/PathwayBrowser/#/R-GGA-4090288 PIAS1,3 SUMOylate MBD1 with SUMO1 IEA Gallus gallus A0A1D5PBX2 R-GGA-73739 https://reactome.org/PathwayBrowser/#/R-GGA-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter IEA Gallus gallus A0A1D5PBX2 R-GGA-8943780 https://reactome.org/PathwayBrowser/#/R-GGA-8943780 SALL4 recruits NuRD to PTEN gene IEA Gallus gallus A0A1D5PBX2 R-GGA-9679787 https://reactome.org/PathwayBrowser/#/R-GGA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Gallus gallus A0A1D5PBX9 R-GGA-416639 https://reactome.org/PathwayBrowser/#/R-GGA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Gallus gallus A0A1D5PBX9 R-GGA-416985 https://reactome.org/PathwayBrowser/#/R-GGA-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Gallus gallus A0A1D5PBX9 R-GGA-421007 https://reactome.org/PathwayBrowser/#/R-GGA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5PBY1 R-GGA-159443 https://reactome.org/PathwayBrowser/#/R-GGA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Gallus gallus A0A1D5PBY1 R-GGA-159567 https://reactome.org/PathwayBrowser/#/R-GGA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Gallus gallus A0A1D5PBY1 R-GGA-177157 https://reactome.org/PathwayBrowser/#/R-GGA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Gallus gallus A0A1D5PBY1 R-GGA-9749971 https://reactome.org/PathwayBrowser/#/R-GGA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Gallus gallus A0A1D5PBZ3 R-GGA-432164 https://reactome.org/PathwayBrowser/#/R-GGA-432164 Ca2+ influx into the post-synaptic cell IEA Gallus gallus A0A1D5PBZ3 R-GGA-438037 https://reactome.org/PathwayBrowser/#/R-GGA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5PBZ3 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5PBZ3 R-GGA-6798749 https://reactome.org/PathwayBrowser/#/R-GGA-6798749 Exocytosis of specific granule lumen proteins IEA Gallus gallus A0A1D5PBZ9 R-GGA-6798747 https://reactome.org/PathwayBrowser/#/R-GGA-6798747 Exocytosis of tertiary granule membrane proteins IEA Gallus gallus A0A1D5PBZ9 R-GGA-6799350 https://reactome.org/PathwayBrowser/#/R-GGA-6799350 Exocytosis of specific granule membrane proteins IEA Gallus gallus A0A1D5PC06 R-GGA-2465890 https://reactome.org/PathwayBrowser/#/R-GGA-2465890 DDR2 binds collagen type I, II, III, V, X fibrils IEA Gallus gallus A0A1D5PC23 R-GGA-163764 https://reactome.org/PathwayBrowser/#/R-GGA-163764 D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate IEA Gallus gallus A0A1D5PC23 R-GGA-71334 https://reactome.org/PathwayBrowser/#/R-GGA-71334 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate IEA Gallus gallus A0A1D5PC33 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus A0A1D5PC33 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus A0A1D5PC33 R-GGA-8980691 https://reactome.org/PathwayBrowser/#/R-GGA-8980691 RHOA GEFs activate RHOA IEA Gallus gallus A0A1D5PC33 R-GGA-9013023 https://reactome.org/PathwayBrowser/#/R-GGA-9013023 RHOB GEFs activate RHOB IEA Gallus gallus A0A1D5PC33 R-GGA-9013109 https://reactome.org/PathwayBrowser/#/R-GGA-9013109 RHOC GEFs activate RHOC IEA Gallus gallus A0A1D5PC35 R-GGA-429860 https://reactome.org/PathwayBrowser/#/R-GGA-429860 DCP1-DCP2 complex decaps mRNA IEA Gallus gallus A0A1D5PC35 R-GGA-429978 https://reactome.org/PathwayBrowser/#/R-GGA-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Gallus gallus A0A1D5PC43 R-GGA-5683964 https://reactome.org/PathwayBrowser/#/R-GGA-5683964 ATM phosphorylates EYA1-4 IEA Gallus gallus A0A1D5PC43 R-GGA-5683967 https://reactome.org/PathwayBrowser/#/R-GGA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Gallus gallus A0A1D5PC67 R-GGA-173680 https://reactome.org/PathwayBrowser/#/R-GGA-173680 Activation of C5 IEA Gallus gallus A0A1D5PC67 R-GGA-173705 https://reactome.org/PathwayBrowser/#/R-GGA-173705 C5b binds C6 IEA Gallus gallus A0A1D5PC67 R-GGA-173709 https://reactome.org/PathwayBrowser/#/R-GGA-173709 C7 binds C5b:C6 IEA Gallus gallus A0A1D5PC67 R-GGA-173720 https://reactome.org/PathwayBrowser/#/R-GGA-173720 C5b:C6:C7 translocates to the plasma membrane IEA Gallus gallus A0A1D5PC67 R-GGA-173723 https://reactome.org/PathwayBrowser/#/R-GGA-173723 C8 binds C5b:C6:C7 IEA Gallus gallus A0A1D5PC67 R-GGA-2530453 https://reactome.org/PathwayBrowser/#/R-GGA-2530453 Vitronectin (VTN) binds to C5b:C6:C7 IEA Gallus gallus A0A1D5PC67 R-GGA-375395 https://reactome.org/PathwayBrowser/#/R-GGA-375395 C5a receptor binds C5a anaphylatoxin IEA Gallus gallus A0A1D5PC67 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5PC67 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5PC67 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5PC67 R-GGA-8852716 https://reactome.org/PathwayBrowser/#/R-GGA-8852716 Thrombin, ELANE cleave C5 IEA Gallus gallus A0A1D5PC67 R-GGA-8852809 https://reactome.org/PathwayBrowser/#/R-GGA-8852809 CPN, CPB2 cleave C3a, C5a IEA Gallus gallus A0A1D5PC67 R-GGA-964811 https://reactome.org/PathwayBrowser/#/R-GGA-964811 C5AR2 binds anaphylatoxins and thier desArginated derivatives IEA Gallus gallus A0A1D5PC67 R-GGA-9691621 https://reactome.org/PathwayBrowser/#/R-GGA-9691621 C5 binds C5 inhibitors IEA Gallus gallus A0A1D5PC69 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PC75 R-GGA-5690565 https://reactome.org/PathwayBrowser/#/R-GGA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Gallus gallus A0A1D5PC88 R-GGA-195275 https://reactome.org/PathwayBrowser/#/R-GGA-195275 Phosphorylation of APC component of the destruction complex IEA Gallus gallus A0A1D5PC88 R-GGA-195280 https://reactome.org/PathwayBrowser/#/R-GGA-195280 Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex IEA Gallus gallus A0A1D5PC88 R-GGA-195283 https://reactome.org/PathwayBrowser/#/R-GGA-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Gallus gallus A0A1D5PC88 R-GGA-195287 https://reactome.org/PathwayBrowser/#/R-GGA-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Gallus gallus A0A1D5PC88 R-GGA-195300 https://reactome.org/PathwayBrowser/#/R-GGA-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Gallus gallus A0A1D5PC88 R-GGA-195304 https://reactome.org/PathwayBrowser/#/R-GGA-195304 Association of beta-catenin with the destruction complex IEA Gallus gallus A0A1D5PC88 R-GGA-195318 https://reactome.org/PathwayBrowser/#/R-GGA-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Gallus gallus A0A1D5PC88 R-GGA-202947 https://reactome.org/PathwayBrowser/#/R-GGA-202947 Caspase mediated cleavage of APC IEA Gallus gallus A0A1D5PC88 R-GGA-2130279 https://reactome.org/PathwayBrowser/#/R-GGA-2130279 Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex IEA Gallus gallus A0A1D5PC88 R-GGA-2130282 https://reactome.org/PathwayBrowser/#/R-GGA-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Gallus gallus A0A1D5PC88 R-GGA-2130286 https://reactome.org/PathwayBrowser/#/R-GGA-2130286 Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) IEA Gallus gallus A0A1D5PC88 R-GGA-3361751 https://reactome.org/PathwayBrowser/#/R-GGA-3361751 beta-catenin is replaced by repression complexes at the promoter IEA Gallus gallus A0A1D5PC88 R-GGA-5229343 https://reactome.org/PathwayBrowser/#/R-GGA-5229343 AXIN is phosphorylated in the destruction complex IEA Gallus gallus A0A1D5PC88 R-GGA-6781905 https://reactome.org/PathwayBrowser/#/R-GGA-6781905 ZRANB1 binds APC IEA Gallus gallus A0A1D5PC91 R-GGA-5666070 https://reactome.org/PathwayBrowser/#/R-GGA-5666070 RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes IEA Gallus gallus A0A1D5PC91 R-GGA-9013009 https://reactome.org/PathwayBrowser/#/R-GGA-9013009 RHOA binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PC91 R-GGA-9013024 https://reactome.org/PathwayBrowser/#/R-GGA-9013024 RHOB binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PC91 R-GGA-9013110 https://reactome.org/PathwayBrowser/#/R-GGA-9013110 RHOC binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PC91 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PC91 R-GGA-9014294 https://reactome.org/PathwayBrowser/#/R-GGA-9014294 RAC2 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PC91 R-GGA-9014449 https://reactome.org/PathwayBrowser/#/R-GGA-9014449 RHOG binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PC91 R-GGA-9018746 https://reactome.org/PathwayBrowser/#/R-GGA-9018746 RHOQ binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PC91 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PC91 R-GGA-9690493 https://reactome.org/PathwayBrowser/#/R-GGA-9690493 RHOB binds effectors on endosomes IEA Gallus gallus A0A1D5PC91 R-GGA-9693125 https://reactome.org/PathwayBrowser/#/R-GGA-9693125 RHOF binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PC91 R-GGA-9693198 https://reactome.org/PathwayBrowser/#/R-GGA-9693198 RHOD binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PCA0 R-GGA-8932413 https://reactome.org/PathwayBrowser/#/R-GGA-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Gallus gallus A0A1D5PCB0 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PCB1 R-GGA-9009065 https://reactome.org/PathwayBrowser/#/R-GGA-9009065 FOXA1 and GATA3 bind to CCND1 promoter IEA Gallus gallus A0A1D5PCB1 R-GGA-9009371 https://reactome.org/PathwayBrowser/#/R-GGA-9009371 Binding of AP1 transcriptional activator complexes to CCND1 promoter IEA Gallus gallus A0A1D5PCB1 R-GGA-9009533 https://reactome.org/PathwayBrowser/#/R-GGA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Gallus gallus A0A1D5PCB1 R-GGA-9009536 https://reactome.org/PathwayBrowser/#/R-GGA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Gallus gallus A0A1D5PCB1 R-GGA-9009541 https://reactome.org/PathwayBrowser/#/R-GGA-9009541 ESR1 binds to TFF1 gene promoter IEA Gallus gallus A0A1D5PCB1 R-GGA-9018499 https://reactome.org/PathwayBrowser/#/R-GGA-9018499 ESR1:ESTG and EP300 are recruited to TFF3 promoter IEA Gallus gallus A0A1D5PCB1 R-GGA-9023860 https://reactome.org/PathwayBrowser/#/R-GGA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Gallus gallus A0A1D5PCB1 R-GGA-9038163 https://reactome.org/PathwayBrowser/#/R-GGA-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Gallus gallus A0A1D5PCB3 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus A0A1D5PCB3 R-GGA-5678706 https://reactome.org/PathwayBrowser/#/R-GGA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Gallus gallus A0A1D5PCD1 R-GGA-9013009 https://reactome.org/PathwayBrowser/#/R-GGA-9013009 RHOA binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PCD1 R-GGA-9013024 https://reactome.org/PathwayBrowser/#/R-GGA-9013024 RHOB binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PCD1 R-GGA-9013110 https://reactome.org/PathwayBrowser/#/R-GGA-9013110 RHOC binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PCD1 R-GGA-9696268 https://reactome.org/PathwayBrowser/#/R-GGA-9696268 RND3 binds effectors IEA Gallus gallus A0A1D5PCD1 R-GGA-9696271 https://reactome.org/PathwayBrowser/#/R-GGA-9696271 RND1 binds effectors IEA Gallus gallus A0A1D5PCD6 R-GGA-5690043 https://reactome.org/PathwayBrowser/#/R-GGA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus A0A1D5PCF0 R-GGA-1181149 https://reactome.org/PathwayBrowser/#/R-GGA-1181149 ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin IEA Gallus gallus A0A1D5PCF0 R-GGA-1181153 https://reactome.org/PathwayBrowser/#/R-GGA-1181153 Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B IEA Gallus gallus A0A1D5PCF0 R-GGA-1549526 https://reactome.org/PathwayBrowser/#/R-GGA-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Gallus gallus A0A1D5PCF8 R-GGA-1296127 https://reactome.org/PathwayBrowser/#/R-GGA-1296127 Activation of voltage gated Potassium channels IEA Gallus gallus A0A1D5PCF9 R-GGA-6807872 https://reactome.org/PathwayBrowser/#/R-GGA-6807872 Active ARF recruits coatomer IEA Gallus gallus A0A1D5PCF9 R-GGA-6807877 https://reactome.org/PathwayBrowser/#/R-GGA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Gallus gallus A0A1D5PCF9 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1D5PCF9 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5PCF9 R-GGA-6809011 https://reactome.org/PathwayBrowser/#/R-GGA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Gallus gallus A0A1D5PCF9 R-GGA-6811417 https://reactome.org/PathwayBrowser/#/R-GGA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Gallus gallus A0A1D5PCF9 R-GGA-6811418 https://reactome.org/PathwayBrowser/#/R-GGA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Gallus gallus A0A1D5PCF9 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5PCF9 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5PCH3 R-GGA-1964501 https://reactome.org/PathwayBrowser/#/R-GGA-1964501 Addition of galactose to Core 6 glycoprotein IEA Gallus gallus A0A1D5PCH3 R-GGA-1964505 https://reactome.org/PathwayBrowser/#/R-GGA-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Gallus gallus A0A1D5PCH3 R-GGA-5694487 https://reactome.org/PathwayBrowser/#/R-GGA-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Gallus gallus A0A1D5PCH3 R-GGA-6786012 https://reactome.org/PathwayBrowser/#/R-GGA-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Gallus gallus A0A1D5PCH3 R-GGA-8858500 https://reactome.org/PathwayBrowser/#/R-GGA-8858500 CLEC10A binds Tn-MUC1 IEA Gallus gallus A0A1D5PCH3 R-GGA-913675 https://reactome.org/PathwayBrowser/#/R-GGA-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Gallus gallus A0A1D5PCH3 R-GGA-914005 https://reactome.org/PathwayBrowser/#/R-GGA-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Gallus gallus A0A1D5PCH3 R-GGA-914006 https://reactome.org/PathwayBrowser/#/R-GGA-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Gallus gallus A0A1D5PCH3 R-GGA-914008 https://reactome.org/PathwayBrowser/#/R-GGA-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Gallus gallus A0A1D5PCH3 R-GGA-914010 https://reactome.org/PathwayBrowser/#/R-GGA-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Gallus gallus A0A1D5PCH3 R-GGA-914012 https://reactome.org/PathwayBrowser/#/R-GGA-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Gallus gallus A0A1D5PCH3 R-GGA-914017 https://reactome.org/PathwayBrowser/#/R-GGA-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Gallus gallus A0A1D5PCH3 R-GGA-914018 https://reactome.org/PathwayBrowser/#/R-GGA-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Gallus gallus A0A1D5PCH3 R-GGA-977071 https://reactome.org/PathwayBrowser/#/R-GGA-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Gallus gallus A0A1D5PCH3 R-GGA-981497 https://reactome.org/PathwayBrowser/#/R-GGA-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Gallus gallus A0A1D5PCH3 R-GGA-981809 https://reactome.org/PathwayBrowser/#/R-GGA-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Gallus gallus A0A1D5PCH3 R-GGA-981814 https://reactome.org/PathwayBrowser/#/R-GGA-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Gallus gallus A0A1D5PCH8 R-GGA-8847534 https://reactome.org/PathwayBrowser/#/R-GGA-8847534 RAB43 hydrolyses GTP IEA Gallus gallus A0A1D5PCH8 R-GGA-8847537 https://reactome.org/PathwayBrowser/#/R-GGA-8847537 RAB43:GTP binds USP8NL IEA Gallus gallus A0A1D5PCI4 R-GGA-111925 https://reactome.org/PathwayBrowser/#/R-GGA-111925 cAMP induces dissociation of inactive PKA tetramers IEA Gallus gallus A0A1D5PCI4 R-GGA-5610749 https://reactome.org/PathwayBrowser/#/R-GGA-5610749 cAMP dissociates PKA, promoting GLI processing IEA Gallus gallus A0A1D5PCI4 R-GGA-8951727 https://reactome.org/PathwayBrowser/#/R-GGA-8951727 cAMP binds PKA tetramer IEA Gallus gallus A0A1D5PCI4 R-GGA-992708 https://reactome.org/PathwayBrowser/#/R-GGA-992708 Dual-specific AKAPs bind type I and II PKA regulatory subunits IEA Gallus gallus A0A1D5PCI5 R-GGA-8951648 https://reactome.org/PathwayBrowser/#/R-GGA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Gallus gallus A0A1D5PCI5 R-GGA-8951656 https://reactome.org/PathwayBrowser/#/R-GGA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Gallus gallus A0A1D5PCI5 R-GGA-8951661 https://reactome.org/PathwayBrowser/#/R-GGA-8951661 Transfer of NEDD8 to AcM-UBE2M IEA Gallus gallus A0A1D5PCI5 R-GGA-8951751 https://reactome.org/PathwayBrowser/#/R-GGA-8951751 Doubly neddylated UBA3:NAE1 binds AcM-UBE2M IEA Gallus gallus A0A1D5PCI5 R-GGA-8951764 https://reactome.org/PathwayBrowser/#/R-GGA-8951764 Transfer of NEDD8 to AcM-UBE2F IEA Gallus gallus A0A1D5PCI5 R-GGA-8951766 https://reactome.org/PathwayBrowser/#/R-GGA-8951766 Doubly neddylated UBA3:NAE1 binds AcM-UBE2F IEA Gallus gallus A0A1D5PCI8 R-GGA-372505 https://reactome.org/PathwayBrowser/#/R-GGA-372505 Acetylcholine synaptic vesicle docking and priming IEA Gallus gallus A0A1D5PCI8 R-GGA-374922 https://reactome.org/PathwayBrowser/#/R-GGA-374922 Noradrenalin synaptic vesicle docking and priming IEA Gallus gallus A0A1D5PCI8 R-GGA-388824 https://reactome.org/PathwayBrowser/#/R-GGA-388824 PTPRF, PTPRS, PTPRD bind Liprins IEA Gallus gallus A0A1D5PCK8 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PCK8 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PCK8 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PCK8 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PCP4 R-GGA-376419 https://reactome.org/PathwayBrowser/#/R-GGA-376419 Formation of NR-MED1 Coactivator Complex IEA Gallus gallus A0A1D5PCP4 R-GGA-382096 https://reactome.org/PathwayBrowser/#/R-GGA-382096 Formation of NR-NCOR Corepressor Complex IEA Gallus gallus A0A1D5PCP9 R-GGA-5205663 https://reactome.org/PathwayBrowser/#/R-GGA-5205663 LC3 binds the autophagosome membrane Atg5-Atg12 complex IEA Gallus gallus A0A1D5PCP9 R-GGA-5678490 https://reactome.org/PathwayBrowser/#/R-GGA-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Gallus gallus A0A1D5PCP9 R-GGA-5679255 https://reactome.org/PathwayBrowser/#/R-GGA-5679255 WIPI2 binds ATG12:ATG5:ATG16L IEA Gallus gallus A0A1D5PCP9 R-GGA-5682010 https://reactome.org/PathwayBrowser/#/R-GGA-5682010 ATG10:ATG12 binds ATG5 IEA Gallus gallus A0A1D5PCP9 R-GGA-5682012 https://reactome.org/PathwayBrowser/#/R-GGA-5682012 ATG5:ATG12 binds ATG16L1 IEA Gallus gallus A0A1D5PCP9 R-GGA-5682690 https://reactome.org/PathwayBrowser/#/R-GGA-5682690 ATG10 dissociates from ATG12:ATG5 IEA Gallus gallus A0A1D5PCP9 R-GGA-5683588 https://reactome.org/PathwayBrowser/#/R-GGA-5683588 ATG10 transfers ATG12 from ATG10 to ATG5 IEA Gallus gallus A0A1D5PCP9 R-GGA-8959571 https://reactome.org/PathwayBrowser/#/R-GGA-8959571 LC3 binds the autophagosome membrane Atg5-Atg12 complex IEA Gallus gallus A0A1D5PCQ0 R-GGA-5336443 https://reactome.org/PathwayBrowser/#/R-GGA-5336443 LIN7, CASK and APBA1 bind IEA Gallus gallus A0A1D5PCQ7 R-GGA-2574840 https://reactome.org/PathwayBrowser/#/R-GGA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Gallus gallus A0A1D5PCQ7 R-GGA-2574845 https://reactome.org/PathwayBrowser/#/R-GGA-2574845 AJUBA binds centrosome-associated AURKA IEA Gallus gallus A0A1D5PCQ7 R-GGA-3000310 https://reactome.org/PathwayBrowser/#/R-GGA-3000310 AURKA phosphorylates PLK1 IEA Gallus gallus A0A1D5PCQ7 R-GGA-3000319 https://reactome.org/PathwayBrowser/#/R-GGA-3000319 BORA binds PLK1 and AURKA IEA Gallus gallus A0A1D5PCQ7 R-GGA-380272 https://reactome.org/PathwayBrowser/#/R-GGA-380272 Plk1-mediated phosphorylation of Nlp IEA Gallus gallus A0A1D5PCQ7 R-GGA-380283 https://reactome.org/PathwayBrowser/#/R-GGA-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Gallus gallus A0A1D5PCQ7 R-GGA-380294 https://reactome.org/PathwayBrowser/#/R-GGA-380294 Loss of C-Nap-1 from centrosomes IEA Gallus gallus A0A1D5PCQ7 R-GGA-380311 https://reactome.org/PathwayBrowser/#/R-GGA-380311 Recruitment of Plk1 to centrosomes IEA Gallus gallus A0A1D5PCQ7 R-GGA-380455 https://reactome.org/PathwayBrowser/#/R-GGA-380455 Recruitment of CDK11p58 to the centrosomes IEA Gallus gallus A0A1D5PCQ7 R-GGA-380508 https://reactome.org/PathwayBrowser/#/R-GGA-380508 Translocation of NuMA to the centrosomes IEA Gallus gallus A0A1D5PCQ7 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5PCQ7 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus A0A1D5PCQ7 R-GGA-5626228 https://reactome.org/PathwayBrowser/#/R-GGA-5626228 The distal appendage proteins recruit TTBK2 IEA Gallus gallus A0A1D5PCQ7 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1D5PCQ7 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1D5PCQ7 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1D5PCQ7 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5PCQ7 R-GGA-8849350 https://reactome.org/PathwayBrowser/#/R-GGA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Gallus gallus A0A1D5PCQ7 R-GGA-8849353 https://reactome.org/PathwayBrowser/#/R-GGA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Gallus gallus A0A1D5PCQ7 R-GGA-8853405 https://reactome.org/PathwayBrowser/#/R-GGA-8853405 TPX2 binds AURKA at centrosomes IEA Gallus gallus A0A1D5PCQ7 R-GGA-8853419 https://reactome.org/PathwayBrowser/#/R-GGA-8853419 TPX2 promotes AURKA autophosphorylation IEA Gallus gallus A0A1D5PCR1 R-GGA-421831 https://reactome.org/PathwayBrowser/#/R-GGA-421831 trans-Golgi Network Coat Assembly IEA Gallus gallus A0A1D5PCR1 R-GGA-421835 https://reactome.org/PathwayBrowser/#/R-GGA-421835 trans-Golgi Network Vesicle Scission IEA Gallus gallus A0A1D5PCR1 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5PCR1 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5PCR1 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5PCR1 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5PCR1 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5PCR1 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PCR1 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PCR1 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5PCR1 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5PCR2 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus A0A1D5PCR2 R-GGA-203979 https://reactome.org/PathwayBrowser/#/R-GGA-203979 Coat Assembly IEA Gallus gallus A0A1D5PCR2 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus A0A1D5PCR2 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus A0A1D5PCR2 R-GGA-5694415 https://reactome.org/PathwayBrowser/#/R-GGA-5694415 SEC24A,B:SEC23A bind SEC22B IEA Gallus gallus A0A1D5PCR2 R-GGA-5694417 https://reactome.org/PathwayBrowser/#/R-GGA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Gallus gallus A0A1D5PCR2 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus A0A1D5PCR2 R-GGA-5694421 https://reactome.org/PathwayBrowser/#/R-GGA-5694421 PP6 dephosphorylates SEC24 IEA Gallus gallus A0A1D5PCR2 R-GGA-5694522 https://reactome.org/PathwayBrowser/#/R-GGA-5694522 Inner coat assembly and cargo binding IEA Gallus gallus A0A1D5PCR2 R-GGA-5694527 https://reactome.org/PathwayBrowser/#/R-GGA-5694527 Loss of SAR1B GTPase IEA Gallus gallus A0A1D5PCR2 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus A0A1D5PCR2 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus A0A1D5PCR2 R-GGA-983425 https://reactome.org/PathwayBrowser/#/R-GGA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Gallus gallus A0A1D5PCS7 R-GGA-6814670 https://reactome.org/PathwayBrowser/#/R-GGA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Gallus gallus A0A1D5PCS7 R-GGA-6814671 https://reactome.org/PathwayBrowser/#/R-GGA-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Gallus gallus A0A1D5PCS7 R-GGA-6814675 https://reactome.org/PathwayBrowser/#/R-GGA-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Gallus gallus A0A1D5PCU0 R-GGA-1222516 https://reactome.org/PathwayBrowser/#/R-GGA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Gallus gallus A0A1D5PCU0 R-GGA-74723 https://reactome.org/PathwayBrowser/#/R-GGA-74723 Endosome acidification IEA Gallus gallus A0A1D5PCU0 R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus A0A1D5PCU3 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PCU3 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PCU3 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PCU3 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PCU8 R-GGA-2990840 https://reactome.org/PathwayBrowser/#/R-GGA-2990840 SENP1,2,5 proteolytically process SUMO1 IEA Gallus gallus A0A1D5PCU8 R-GGA-2990842 https://reactome.org/PathwayBrowser/#/R-GGA-2990842 SENP1,2,5 proteolytically process SUMO2 IEA Gallus gallus A0A1D5PCU8 R-GGA-2993763 https://reactome.org/PathwayBrowser/#/R-GGA-2993763 SENP1,2,5 proteolytically process SUMO3 IEA Gallus gallus A0A1D5PCV5 R-GGA-939763 https://reactome.org/PathwayBrowser/#/R-GGA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Gallus gallus A0A1D5PCV5 R-GGA-947591 https://reactome.org/PathwayBrowser/#/R-GGA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Gallus gallus A0A1D5PCW1 R-GGA-5333658 https://reactome.org/PathwayBrowser/#/R-GGA-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Gallus gallus A0A1D5PCW8 R-GGA-6811431 https://reactome.org/PathwayBrowser/#/R-GGA-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Gallus gallus A0A1D5PCW8 R-GGA-6814091 https://reactome.org/PathwayBrowser/#/R-GGA-6814091 ARL1 recruits TGN Golgin homodimers IEA Gallus gallus A0A1D5PCW8 R-GGA-6814682 https://reactome.org/PathwayBrowser/#/R-GGA-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Gallus gallus A0A1D5PCW9 R-GGA-5223305 https://reactome.org/PathwayBrowser/#/R-GGA-5223305 ABCE1 binds RNASEL, inhibiting it IEA Gallus gallus A0A1D5PCW9 R-GGA-8985201 https://reactome.org/PathwayBrowser/#/R-GGA-8985201 ABCE1 binds RNASEL IEA Gallus gallus A0A1D5PCW9 R-GGA-9009936 https://reactome.org/PathwayBrowser/#/R-GGA-9009936 RNASEL cleaves cellular ssRNA IEA Gallus gallus A0A1D5PCX2 R-GGA-5682388 https://reactome.org/PathwayBrowser/#/R-GGA-5682388 Autophagosome maturation IEA Gallus gallus A0A1D5PCX2 R-GGA-917693 https://reactome.org/PathwayBrowser/#/R-GGA-917693 ESCRT Disassembly IEA Gallus gallus A0A1D5PCX2 R-GGA-917700 https://reactome.org/PathwayBrowser/#/R-GGA-917700 MVB Vesicle Formation IEA Gallus gallus A0A1D5PCX2 R-GGA-9647619 https://reactome.org/PathwayBrowser/#/R-GGA-9647619 GSDMD forms ring‐shaped oligomers IEA Gallus gallus A0A1D5PCX2 R-GGA-9668389 https://reactome.org/PathwayBrowser/#/R-GGA-9668389 VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations IEA Gallus gallus A0A1D5PCX2 R-GGA-9668395 https://reactome.org/PathwayBrowser/#/R-GGA-9668395 CHMP7 binds CC2D1B IEA Gallus gallus A0A1D5PCX2 R-GGA-9668405 https://reactome.org/PathwayBrowser/#/R-GGA-9668405 SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin IEA Gallus gallus A0A1D5PD02 R-GGA-8852128 https://reactome.org/PathwayBrowser/#/R-GGA-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Gallus gallus A0A1D5PD02 R-GGA-8852129 https://reactome.org/PathwayBrowser/#/R-GGA-8852129 UBA1 conjugates ubiquitin to cytosolic E2 enzymes IEA Gallus gallus A0A1D5PD02 R-GGA-8852130 https://reactome.org/PathwayBrowser/#/R-GGA-8852130 UBA1 conjugates ubiquitin to nuclear E2 enzymes IEA Gallus gallus A0A1D5PD02 R-GGA-8852131 https://reactome.org/PathwayBrowser/#/R-GGA-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Gallus gallus A0A1D5PD02 R-GGA-8852132 https://reactome.org/PathwayBrowser/#/R-GGA-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Gallus gallus A0A1D5PD02 R-GGA-8852133 https://reactome.org/PathwayBrowser/#/R-GGA-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Gallus gallus A0A1D5PD02 R-GGA-8852134 https://reactome.org/PathwayBrowser/#/R-GGA-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Gallus gallus A0A1D5PD02 R-GGA-8852136 https://reactome.org/PathwayBrowser/#/R-GGA-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Gallus gallus A0A1D5PD02 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PD02 R-GGA-983152 https://reactome.org/PathwayBrowser/#/R-GGA-983152 Transfer of ubiquitin from E1 to E2 IEA Gallus gallus A0A1D5PD02 R-GGA-983153 https://reactome.org/PathwayBrowser/#/R-GGA-983153 E1 mediated ubiquitin activation IEA Gallus gallus A0A1D5PD02 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PD02 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PD08 R-GGA-965019 https://reactome.org/PathwayBrowser/#/R-GGA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Gallus gallus A0A1D5PD08 R-GGA-965079 https://reactome.org/PathwayBrowser/#/R-GGA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Gallus gallus A0A1D5PD25 R-GGA-9693198 https://reactome.org/PathwayBrowser/#/R-GGA-9693198 RHOD binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PD32 R-GGA-3900047 https://reactome.org/PathwayBrowser/#/R-GGA-3900047 SUMOylation of DDX17 with SUMO1 IEA Gallus gallus A0A1D5PD64 R-GGA-3228469 https://reactome.org/PathwayBrowser/#/R-GGA-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Gallus gallus A0A1D5PD64 R-GGA-3238999 https://reactome.org/PathwayBrowser/#/R-GGA-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 IEA Gallus gallus A0A1D5PD64 R-GGA-450296 https://reactome.org/PathwayBrowser/#/R-GGA-450296 Phosphorylated MKK3/MKK6 migrates to nucleus IEA Gallus gallus A0A1D5PD64 R-GGA-450333 https://reactome.org/PathwayBrowser/#/R-GGA-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Gallus gallus A0A1D5PD64 R-GGA-450346 https://reactome.org/PathwayBrowser/#/R-GGA-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Gallus gallus A0A1D5PD81 R-GGA-5665727 https://reactome.org/PathwayBrowser/#/R-GGA-5665727 FMNL2 binds CDC42:GTP IEA Gallus gallus A0A1D5PD81 R-GGA-5665748 https://reactome.org/PathwayBrowser/#/R-GGA-5665748 FMNL2 binds RHOC:GTP IEA Gallus gallus A0A1D5PD81 R-GGA-9013110 https://reactome.org/PathwayBrowser/#/R-GGA-9013110 RHOC binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PD82 R-GGA-1296039 https://reactome.org/PathwayBrowser/#/R-GGA-1296039 Activation of Ca2+ activated Potassium channels with small conductance IEA Gallus gallus A0A1D5PD83 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PD83 R-GGA-9014294 https://reactome.org/PathwayBrowser/#/R-GGA-9014294 RAC2 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PD83 R-GGA-9018746 https://reactome.org/PathwayBrowser/#/R-GGA-9018746 RHOQ binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PD83 R-GGA-9018766 https://reactome.org/PathwayBrowser/#/R-GGA-9018766 RHOU binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PD83 R-GGA-9018794 https://reactome.org/PathwayBrowser/#/R-GGA-9018794 RHOV binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PD83 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PD86 R-GGA-109343 https://reactome.org/PathwayBrowser/#/R-GGA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Gallus gallus A0A1D5PD93 R-GGA-3247837 https://reactome.org/PathwayBrowser/#/R-GGA-3247837 WNT ligands traffic to the Golgi IEA Gallus gallus A0A1D5PD93 R-GGA-3247840 https://reactome.org/PathwayBrowser/#/R-GGA-3247840 WLS binds WNT ligands in the Golgi IEA Gallus gallus A0A1D5PD93 R-GGA-3247843 https://reactome.org/PathwayBrowser/#/R-GGA-3247843 secretion of WNT ligands IEA Gallus gallus A0A1D5PD93 R-GGA-3247844 https://reactome.org/PathwayBrowser/#/R-GGA-3247844 WNT ligands traffic to the plasma membrane IEA Gallus gallus A0A1D5PD93 R-GGA-3781941 https://reactome.org/PathwayBrowser/#/R-GGA-3781941 WNTs are secreted in exosomes IEA Gallus gallus A0A1D5PD93 R-GGA-3781943 https://reactome.org/PathwayBrowser/#/R-GGA-3781943 WLS:WNT complex is internalized for maturation into exosomes IEA Gallus gallus A0A1D5PDA1 R-GGA-9033235 https://reactome.org/PathwayBrowser/#/R-GGA-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1D5PDA1 R-GGA-9033236 https://reactome.org/PathwayBrowser/#/R-GGA-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Gallus gallus A0A1D5PDA1 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1D5PDA1 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1D5PDA2 R-GGA-1234159 https://reactome.org/PathwayBrowser/#/R-GGA-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Gallus gallus A0A1D5PDA2 R-GGA-1234163 https://reactome.org/PathwayBrowser/#/R-GGA-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Gallus gallus A0A1D5PDA2 R-GGA-1234169 https://reactome.org/PathwayBrowser/#/R-GGA-1234169 Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Gallus gallus A0A1D5PDA2 R-GGA-1234172 https://reactome.org/PathwayBrowser/#/R-GGA-1234172 Nuclear VBC complex ubiquitinylates HIF-alpha IEA Gallus gallus A0A1D5PDA2 R-GGA-1234173 https://reactome.org/PathwayBrowser/#/R-GGA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Gallus gallus A0A1D5PDA2 R-GGA-1234175 https://reactome.org/PathwayBrowser/#/R-GGA-1234175 ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol IEA Gallus gallus A0A1D5PDA2 R-GGA-1234177 https://reactome.org/PathwayBrowser/#/R-GGA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Gallus gallus A0A1D5PDA2 R-GGA-1234183 https://reactome.org/PathwayBrowser/#/R-GGA-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Gallus gallus A0A1D5PDA2 R-GGA-8952626 https://reactome.org/PathwayBrowser/#/R-GGA-8952626 AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PDA2 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5PDA2 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5PDA2 R-GGA-8956099 https://reactome.org/PathwayBrowser/#/R-GGA-8956099 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 IEA Gallus gallus A0A1D5PDA2 R-GGA-8956103 https://reactome.org/PathwayBrowser/#/R-GGA-8956103 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha IEA Gallus gallus A0A1D5PDA2 R-GGA-8956106 https://reactome.org/PathwayBrowser/#/R-GGA-8956106 VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha IEA Gallus gallus A0A1D5PDA2 R-GGA-9755303 https://reactome.org/PathwayBrowser/#/R-GGA-9755303 26S proteasome degrades HIFalpha IEA Gallus gallus A0A1D5PDA2 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PDA2 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PDA2 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PDA2 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PDB8 R-GGA-1299318 https://reactome.org/PathwayBrowser/#/R-GGA-1299318 Activation of TASK IEA Gallus gallus A0A1D5PDB8 R-GGA-5578910 https://reactome.org/PathwayBrowser/#/R-GGA-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Gallus gallus A0A1D5PDC8 R-GGA-1482695 https://reactome.org/PathwayBrowser/#/R-GGA-1482695 G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) IEA Gallus gallus A0A1D5PDC8 R-GGA-75886 https://reactome.org/PathwayBrowser/#/R-GGA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] IEA Gallus gallus A0A1D5PDE6 R-GGA-399978 https://reactome.org/PathwayBrowser/#/R-GGA-399978 Protein kinase C, alpha type phosphorylates MARCKS IEA Gallus gallus A0A1D5PDE8 R-GGA-156673 https://reactome.org/PathwayBrowser/#/R-GGA-156673 Regulation of KIF23 (MKLP1) by phosphorylation IEA Gallus gallus A0A1D5PDE8 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5PDE8 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5PDE8 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus A0A1D5PDE8 R-GGA-984648 https://reactome.org/PathwayBrowser/#/R-GGA-984648 Kinesin-6 and RACGAP1 form the heterotetrameric complex centralspindlin IEA Gallus gallus A0A1D5PDF6 R-GGA-204434 https://reactome.org/PathwayBrowser/#/R-GGA-204434 BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 IEA Gallus gallus A0A1D5PDF6 R-GGA-265429 https://reactome.org/PathwayBrowser/#/R-GGA-265429 THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1 IEA Gallus gallus A0A1D5PDF6 R-GGA-8874079 https://reactome.org/PathwayBrowser/#/R-GGA-8874079 PTK2 binds activated MET IEA Gallus gallus A0A1D5PDI5 R-GGA-5226979 https://reactome.org/PathwayBrowser/#/R-GGA-5226979 ADD1:ADD2 binds DMTN IEA Gallus gallus A0A1D5PDJ8 R-GGA-3159253 https://reactome.org/PathwayBrowser/#/R-GGA-3159253 MMAB adenosylates cob(I)alamin IEA Gallus gallus A0A1D5PDK5 R-GGA-482772 https://reactome.org/PathwayBrowser/#/R-GGA-482772 Release of platelet cytosolic components IEA Gallus gallus A0A1D5PDN0 R-GGA-3299569 https://reactome.org/PathwayBrowser/#/R-GGA-3299569 Beta-catenin displaces TLE:HDAC1 from TCF/LEF IEA Gallus gallus A0A1D5PDN0 R-GGA-3322429 https://reactome.org/PathwayBrowser/#/R-GGA-3322429 XIAP monoubiquinates TLE IEA Gallus gallus A0A1D5PDN0 R-GGA-3322431 https://reactome.org/PathwayBrowser/#/R-GGA-3322431 XIAP binds TLE IEA Gallus gallus A0A1D5PDN0 R-GGA-3322434 https://reactome.org/PathwayBrowser/#/R-GGA-3322434 XIAP dissociates from ub-TLE IEA Gallus gallus A0A1D5PDN0 R-GGA-3361751 https://reactome.org/PathwayBrowser/#/R-GGA-3361751 beta-catenin is replaced by repression complexes at the promoter IEA Gallus gallus A0A1D5PDN0 R-GGA-4641229 https://reactome.org/PathwayBrowser/#/R-GGA-4641229 TLE oligomerizes IEA Gallus gallus A0A1D5PDN0 R-GGA-8944349 https://reactome.org/PathwayBrowser/#/R-GGA-8944349 TLE tetramers bind TCF/LEF at WNT promoters IEA Gallus gallus A0A1D5PDN2 R-GGA-166869 https://reactome.org/PathwayBrowser/#/R-GGA-166869 TRAF6 binds MEKK1 IEA Gallus gallus A0A1D5PDN2 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus A0A1D5PDN2 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus A0A1D5PDN2 R-GGA-6799202 https://reactome.org/PathwayBrowser/#/R-GGA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Gallus gallus A0A1D5PDP5 R-GGA-8854222 https://reactome.org/PathwayBrowser/#/R-GGA-8854222 TBC1D3 associates with RAB5 IEA Gallus gallus A0A1D5PDP9 R-GGA-445448 https://reactome.org/PathwayBrowser/#/R-GGA-445448 HHIP binds Hedgehog IEA Gallus gallus A0A1D5PDQ3 R-GGA-210420 https://reactome.org/PathwayBrowser/#/R-GGA-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Gallus gallus A0A1D5PDQ3 R-GGA-265645 https://reactome.org/PathwayBrowser/#/R-GGA-265645 Calcium Influx through Voltage-gated Calcium Channels IEA Gallus gallus A0A1D5PDQ3 R-GGA-5577213 https://reactome.org/PathwayBrowser/#/R-GGA-5577213 LTCC multimer transports Ca2+ from extracellular region to cytosol IEA Gallus gallus A0A1D5PDQ3 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus A0A1D5PDQ4 R-GGA-2028284 https://reactome.org/PathwayBrowser/#/R-GGA-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 IEA Gallus gallus A0A1D5PDQ4 R-GGA-2028555 https://reactome.org/PathwayBrowser/#/R-GGA-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Gallus gallus A0A1D5PDQ4 R-GGA-2028629 https://reactome.org/PathwayBrowser/#/R-GGA-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Gallus gallus A0A1D5PDQ4 R-GGA-2028670 https://reactome.org/PathwayBrowser/#/R-GGA-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Gallus gallus A0A1D5PDQ4 R-GGA-2028679 https://reactome.org/PathwayBrowser/#/R-GGA-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Gallus gallus A0A1D5PDQ4 R-GGA-2028692 https://reactome.org/PathwayBrowser/#/R-GGA-2028692 Cleavage of p-STK4 (p-MST1) by caspase 3 IEA Gallus gallus A0A1D5PDR0 R-GGA-191366 https://reactome.org/PathwayBrowser/#/R-GGA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Gallus gallus A0A1D5PDR7 R-GGA-190519 https://reactome.org/PathwayBrowser/#/R-GGA-190519 Internalization of gap junction plaques IEA Gallus gallus A0A1D5PDR7 R-GGA-190829 https://reactome.org/PathwayBrowser/#/R-GGA-190829 Lysosomal degradation of gap junction plaques IEA Gallus gallus A0A1D5PDR7 R-GGA-196017 https://reactome.org/PathwayBrowser/#/R-GGA-196017 Dynamin is recruited to the gap junction plaque IEA Gallus gallus A0A1D5PDR7 R-GGA-203565 https://reactome.org/PathwayBrowser/#/R-GGA-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Gallus gallus A0A1D5PDR7 R-GGA-203625 https://reactome.org/PathwayBrowser/#/R-GGA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Gallus gallus A0A1D5PDR7 R-GGA-2130641 https://reactome.org/PathwayBrowser/#/R-GGA-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Gallus gallus A0A1D5PDR7 R-GGA-2130725 https://reactome.org/PathwayBrowser/#/R-GGA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Gallus gallus A0A1D5PDR7 R-GGA-2201293 https://reactome.org/PathwayBrowser/#/R-GGA-2201293 Endocytosis of TLR4:LY96:LPS:CD14 IEA Gallus gallus A0A1D5PDR7 R-GGA-421831 https://reactome.org/PathwayBrowser/#/R-GGA-421831 trans-Golgi Network Coat Assembly IEA Gallus gallus A0A1D5PDR7 R-GGA-421835 https://reactome.org/PathwayBrowser/#/R-GGA-421835 trans-Golgi Network Vesicle Scission IEA Gallus gallus A0A1D5PDR7 R-GGA-432706 https://reactome.org/PathwayBrowser/#/R-GGA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Gallus gallus A0A1D5PDR7 R-GGA-432707 https://reactome.org/PathwayBrowser/#/R-GGA-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Gallus gallus A0A1D5PDR7 R-GGA-555065 https://reactome.org/PathwayBrowser/#/R-GGA-555065 Formation of clathrin coated vesicle IEA Gallus gallus A0A1D5PDR7 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5PDR7 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5PDR7 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5PDR7 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5PDR7 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PDR7 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PDR7 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5PDR7 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5PDR7 R-GGA-8951498 https://reactome.org/PathwayBrowser/#/R-GGA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Gallus gallus A0A1D5PDS9 R-GGA-111879 https://reactome.org/PathwayBrowser/#/R-GGA-111879 PIP2 hydrolysis IEA Gallus gallus A0A1D5PDS9 R-GGA-112037 https://reactome.org/PathwayBrowser/#/R-GGA-112037 Inactivation of PLC beta IEA Gallus gallus A0A1D5PDS9 R-GGA-114688 https://reactome.org/PathwayBrowser/#/R-GGA-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Gallus gallus A0A1D5PDS9 R-GGA-1855177 https://reactome.org/PathwayBrowser/#/R-GGA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Gallus gallus A0A1D5PDS9 R-GGA-398040 https://reactome.org/PathwayBrowser/#/R-GGA-398040 Gbeta:gamma activation of PLC beta IEA Gallus gallus A0A1D5PDS9 R-GGA-398193 https://reactome.org/PathwayBrowser/#/R-GGA-398193 PLC beta-mediated PIP2 hydrolysis IEA Gallus gallus A0A1D5PDS9 R-GGA-399998 https://reactome.org/PathwayBrowser/#/R-GGA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Gallus gallus A0A1D5PDS9 R-GGA-500717 https://reactome.org/PathwayBrowser/#/R-GGA-500717 Activation of GRIK3 homomer IEA Gallus gallus A0A1D5PDT5 R-GGA-210420 https://reactome.org/PathwayBrowser/#/R-GGA-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Gallus gallus A0A1D5PDU1 R-GGA-5690870 https://reactome.org/PathwayBrowser/#/R-GGA-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Gallus gallus A0A1D5PDU1 R-GGA-6781905 https://reactome.org/PathwayBrowser/#/R-GGA-6781905 ZRANB1 binds APC IEA Gallus gallus A0A1D5PDU1 R-GGA-8869506 https://reactome.org/PathwayBrowser/#/R-GGA-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Gallus gallus A0A1D5PDU4 R-GGA-1358789 https://reactome.org/PathwayBrowser/#/R-GGA-1358789 Self-ubiquitination of RNF41 IEA Gallus gallus A0A1D5PDU4 R-GGA-1358790 https://reactome.org/PathwayBrowser/#/R-GGA-1358790 RNF41 ubiquitinates ERBB3 IEA Gallus gallus A0A1D5PDU4 R-GGA-1358792 https://reactome.org/PathwayBrowser/#/R-GGA-1358792 RNF41 ubiquitinates activated ERBB3 IEA Gallus gallus A0A1D5PDU4 R-GGA-1358795 https://reactome.org/PathwayBrowser/#/R-GGA-1358795 Deubiquitination of RNF41 by P-USP8 IEA Gallus gallus A0A1D5PDU4 R-GGA-1358797 https://reactome.org/PathwayBrowser/#/R-GGA-1358797 Ubiquitinated RNF41 binds P-USP8 IEA Gallus gallus A0A1D5PDU4 R-GGA-1358798 https://reactome.org/PathwayBrowser/#/R-GGA-1358798 RNF41 binds neuregulin-activated ERBB3 IEA Gallus gallus A0A1D5PDU4 R-GGA-1358801 https://reactome.org/PathwayBrowser/#/R-GGA-1358801 ERBB3 binds RNF41 ubiquitin ligase IEA Gallus gallus A0A1D5PDU4 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PDU4 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PDU4 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PDU4 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PDU6 R-GGA-8867667 https://reactome.org/PathwayBrowser/#/R-GGA-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Gallus gallus A0A1D5PDU7 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A1D5PDU7 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A1D5PDU7 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A1D5PDU7 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A1D5PDU7 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5PDU7 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5PDU7 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5PDU7 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5PDU7 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5PDU7 R-GGA-4655355 https://reactome.org/PathwayBrowser/#/R-GGA-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Gallus gallus A0A1D5PDU7 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A1D5PDU7 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1D5PDV6 R-GGA-156808 https://reactome.org/PathwayBrowser/#/R-GGA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Gallus gallus A0A1D5PDV6 R-GGA-157849 https://reactome.org/PathwayBrowser/#/R-GGA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Gallus gallus A0A1D5PDV6 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1D5PDV6 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus A0A1D5PDV6 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1D5PDV6 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1D5PDV6 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1D5PDV6 R-GGA-72676 https://reactome.org/PathwayBrowser/#/R-GGA-72676 eIF3 and eIF1A bind to the 40S subunit IEA Gallus gallus A0A1D5PDV6 R-GGA-72691 https://reactome.org/PathwayBrowser/#/R-GGA-72691 Formation of the 43S pre-initiation complex IEA Gallus gallus A0A1D5PDV6 R-GGA-72697 https://reactome.org/PathwayBrowser/#/R-GGA-72697 Start codon recognition IEA Gallus gallus A0A1D5PDV6 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1D5PDV6 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5PDV6 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5PDW1 R-GGA-2995389 https://reactome.org/PathwayBrowser/#/R-GGA-2995389 ANKLE2 binds VRK1,(VRK2) IEA Gallus gallus A0A1D5PDW1 R-GGA-9014467 https://reactome.org/PathwayBrowser/#/R-GGA-9014467 RHOG binds effectors at the ER membrane IEA Gallus gallus A0A1D5PDW1 R-GGA-9691174 https://reactome.org/PathwayBrowser/#/R-GGA-9691174 RAC1 binds effectors at the ER membrane IEA Gallus gallus A0A1D5PDW1 R-GGA-9693214 https://reactome.org/PathwayBrowser/#/R-GGA-9693214 RHOD binds effectors at the mitochondrial outer membrane IEA Gallus gallus A0A1D5PDW6 R-GGA-1675949 https://reactome.org/PathwayBrowser/#/R-GGA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Gallus gallus A0A1D5PDW6 R-GGA-1855218 https://reactome.org/PathwayBrowser/#/R-GGA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Gallus gallus A0A1D5PDW6 R-GGA-202237 https://reactome.org/PathwayBrowser/#/R-GGA-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Gallus gallus A0A1D5PDW6 R-GGA-210290 https://reactome.org/PathwayBrowser/#/R-GGA-210290 Interaction of PECAM-1 and SHIP IEA Gallus gallus A0A1D5PDW6 R-GGA-913374 https://reactome.org/PathwayBrowser/#/R-GGA-913374 Phosphorylated SHC1 recruits SHIP IEA Gallus gallus A0A1D5PDX2 R-GGA-427910 https://reactome.org/PathwayBrowser/#/R-GGA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Gallus gallus A0A1D5PDX2 R-GGA-432164 https://reactome.org/PathwayBrowser/#/R-GGA-432164 Ca2+ influx into the post-synaptic cell IEA Gallus gallus A0A1D5PDX2 R-GGA-438037 https://reactome.org/PathwayBrowser/#/R-GGA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5PDX2 R-GGA-5082387 https://reactome.org/PathwayBrowser/#/R-GGA-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Gallus gallus A0A1D5PDX2 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5PDX2 R-GGA-5672969 https://reactome.org/PathwayBrowser/#/R-GGA-5672969 Phosphorylation of RAF IEA Gallus gallus A0A1D5PDX2 R-GGA-909552 https://reactome.org/PathwayBrowser/#/R-GGA-909552 Phosphorylation of STAT1 at Ser727 IEA Gallus gallus A0A1D5PDX6 R-GGA-975389 https://reactome.org/PathwayBrowser/#/R-GGA-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Gallus gallus A0A1D5PE01 R-GGA-193054 https://reactome.org/PathwayBrowser/#/R-GGA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Gallus gallus A0A1D5PE01 R-GGA-193065 https://reactome.org/PathwayBrowser/#/R-GGA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Gallus gallus A0A1D5PE01 R-GGA-193101 https://reactome.org/PathwayBrowser/#/R-GGA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Gallus gallus A0A1D5PE21 R-GGA-2160931 https://reactome.org/PathwayBrowser/#/R-GGA-2160931 Disassembly of tight junctions IEA Gallus gallus A0A1D5PE26 R-GGA-8876188 https://reactome.org/PathwayBrowser/#/R-GGA-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Gallus gallus A0A1D5PE41 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus A0A1D5PE41 R-GGA-6788523 https://reactome.org/PathwayBrowser/#/R-GGA-6788523 NUBPL transfers 4Fe-4S to Complex I subunits IEA Gallus gallus A0A1D5PE41 R-GGA-6799178 https://reactome.org/PathwayBrowser/#/R-GGA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Gallus gallus A0A1D5PE41 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus A0A1D5PE41 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus A0A1D5PE41 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus A0A1D5PE41 R-GGA-6799202 https://reactome.org/PathwayBrowser/#/R-GGA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Gallus gallus A0A1D5PE41 R-GGA-6799203 https://reactome.org/PathwayBrowser/#/R-GGA-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Gallus gallus A0A1D5PE41 R-GGA-6800868 https://reactome.org/PathwayBrowser/#/R-GGA-6800868 NDUF subunits bind to form the IP subcomplex IEA Gallus gallus A0A1D5PE45 R-GGA-5419165 https://reactome.org/PathwayBrowser/#/R-GGA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Gallus gallus A0A1D5PE45 R-GGA-9033235 https://reactome.org/PathwayBrowser/#/R-GGA-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1D5PE45 R-GGA-9033236 https://reactome.org/PathwayBrowser/#/R-GGA-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Gallus gallus A0A1D5PE57 R-GGA-1454757 https://reactome.org/PathwayBrowser/#/R-GGA-1454757 Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 IEA Gallus gallus A0A1D5PE57 R-GGA-1474210 https://reactome.org/PathwayBrowser/#/R-GGA-1474210 Collagen type III degradation by MMP14 IEA Gallus gallus A0A1D5PE57 R-GGA-1474213 https://reactome.org/PathwayBrowser/#/R-GGA-1474213 Collagen type III degradation by MMP1,8,9,13 IEA Gallus gallus A0A1D5PE57 R-GGA-1474266 https://reactome.org/PathwayBrowser/#/R-GGA-1474266 Formation of collagen fibrils IEA Gallus gallus A0A1D5PE57 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus A0A1D5PE57 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus A0A1D5PE57 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus A0A1D5PE57 R-GGA-1981120 https://reactome.org/PathwayBrowser/#/R-GGA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Gallus gallus A0A1D5PE57 R-GGA-2002428 https://reactome.org/PathwayBrowser/#/R-GGA-2002428 Removal of fibrillar collagen N-propeptides IEA Gallus gallus A0A1D5PE57 R-GGA-2002460 https://reactome.org/PathwayBrowser/#/R-GGA-2002460 P4HB binds Collagen chains IEA Gallus gallus A0A1D5PE57 R-GGA-2089971 https://reactome.org/PathwayBrowser/#/R-GGA-2089971 Secretion of collagens IEA Gallus gallus A0A1D5PE57 R-GGA-2213201 https://reactome.org/PathwayBrowser/#/R-GGA-2213201 Formation of collagen fibres IEA Gallus gallus A0A1D5PE57 R-GGA-2327909 https://reactome.org/PathwayBrowser/#/R-GGA-2327909 DCN binds collagen I, II, III, VI fibrils IEA Gallus gallus A0A1D5PE57 R-GGA-2396370 https://reactome.org/PathwayBrowser/#/R-GGA-2396370 VTN binds collagens II, III and V IEA Gallus gallus A0A1D5PE57 R-GGA-2465890 https://reactome.org/PathwayBrowser/#/R-GGA-2465890 DDR2 binds collagen type I, II, III, V, X fibrils IEA Gallus gallus A0A1D5PE57 R-GGA-2473584 https://reactome.org/PathwayBrowser/#/R-GGA-2473584 Collagen type III degradation by MMP15 IEA Gallus gallus A0A1D5PE57 R-GGA-382054 https://reactome.org/PathwayBrowser/#/R-GGA-382054 PDGF binds to extracellular matrix proteins IEA Gallus gallus A0A1D5PE57 R-GGA-8874079 https://reactome.org/PathwayBrowser/#/R-GGA-8874079 PTK2 binds activated MET IEA Gallus gallus A0A1D5PE57 R-GGA-8944240 https://reactome.org/PathwayBrowser/#/R-GGA-8944240 Association of procollagen type III IEA Gallus gallus A0A1D5PE57 R-GGA-8948228 https://reactome.org/PathwayBrowser/#/R-GGA-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Gallus gallus A0A1D5PE57 R-GGA-8948231 https://reactome.org/PathwayBrowser/#/R-GGA-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Gallus gallus A0A1D5PE57 R-GGA-8948232 https://reactome.org/PathwayBrowser/#/R-GGA-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Gallus gallus A0A1D5PE57 R-GGA-8948234 https://reactome.org/PathwayBrowser/#/R-GGA-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Gallus gallus A0A1D5PE70 R-GGA-2730664 https://reactome.org/PathwayBrowser/#/R-GGA-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol IEA Gallus gallus A0A1D5PE74 R-GGA-1474266 https://reactome.org/PathwayBrowser/#/R-GGA-1474266 Formation of collagen fibrils IEA Gallus gallus A0A1D5PE74 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus A0A1D5PE74 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus A0A1D5PE74 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus A0A1D5PE74 R-GGA-1981120 https://reactome.org/PathwayBrowser/#/R-GGA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Gallus gallus A0A1D5PE74 R-GGA-2002428 https://reactome.org/PathwayBrowser/#/R-GGA-2002428 Removal of fibrillar collagen N-propeptides IEA Gallus gallus A0A1D5PE74 R-GGA-2002460 https://reactome.org/PathwayBrowser/#/R-GGA-2002460 P4HB binds Collagen chains IEA Gallus gallus A0A1D5PE74 R-GGA-2089971 https://reactome.org/PathwayBrowser/#/R-GGA-2089971 Secretion of collagens IEA Gallus gallus A0A1D5PE74 R-GGA-8948228 https://reactome.org/PathwayBrowser/#/R-GGA-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Gallus gallus A0A1D5PE74 R-GGA-8948231 https://reactome.org/PathwayBrowser/#/R-GGA-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Gallus gallus A0A1D5PE74 R-GGA-8948232 https://reactome.org/PathwayBrowser/#/R-GGA-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Gallus gallus A0A1D5PE74 R-GGA-8948234 https://reactome.org/PathwayBrowser/#/R-GGA-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Gallus gallus A0A1D5PE83 R-GGA-265295 https://reactome.org/PathwayBrowser/#/R-GGA-265295 Prostaglandin E synthase isomerizes PGH2 to PGE2 IEA Gallus gallus A0A1D5PE83 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5PE93 R-GGA-2529015 https://reactome.org/PathwayBrowser/#/R-GGA-2529015 Dephosphorylation of CK2-modified condensin I IEA Gallus gallus A0A1D5PEB4 R-GGA-5653780 https://reactome.org/PathwayBrowser/#/R-GGA-5653780 USP43 binds ISG:K164,ISG:K168-PCNA IEA Gallus gallus A0A1D5PEC1 R-GGA-1504186 https://reactome.org/PathwayBrowser/#/R-GGA-1504186 DVL recruits GSK3beta:AXIN1 to the receptor complex IEA Gallus gallus A0A1D5PEC1 R-GGA-201677 https://reactome.org/PathwayBrowser/#/R-GGA-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Gallus gallus A0A1D5PEC1 R-GGA-3965444 https://reactome.org/PathwayBrowser/#/R-GGA-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Gallus gallus A0A1D5PEC1 R-GGA-3965447 https://reactome.org/PathwayBrowser/#/R-GGA-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Gallus gallus A0A1D5PEC1 R-GGA-5140741 https://reactome.org/PathwayBrowser/#/R-GGA-5140741 WNT5A binds FZD and ROR receptors IEA Gallus gallus A0A1D5PEC1 R-GGA-5140747 https://reactome.org/PathwayBrowser/#/R-GGA-5140747 FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner IEA Gallus gallus A0A1D5PEC4 R-GGA-8949178 https://reactome.org/PathwayBrowser/#/R-GGA-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix IEA Gallus gallus A0A1D5PEC4 R-GGA-8953461 https://reactome.org/PathwayBrowser/#/R-GGA-8953461 SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex IEA Gallus gallus A0A1D5PED0 R-GGA-373061 https://reactome.org/PathwayBrowser/#/R-GGA-373061 Receptors CCR3, 4 and 5 bind CCL5 ligand IEA Gallus gallus A0A1D5PED0 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5PED0 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5PED0 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5PED5 R-GGA-2995388 https://reactome.org/PathwayBrowser/#/R-GGA-2995388 PP2A dephosphorylates BANF1 IEA Gallus gallus A0A1D5PED5 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5PED5 R-GGA-9865226 https://reactome.org/PathwayBrowser/#/R-GGA-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Gallus gallus A0A1D5PEE1 R-GGA-8868402 https://reactome.org/PathwayBrowser/#/R-GGA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Gallus gallus A0A1D5PEE5 R-GGA-9933559 https://reactome.org/PathwayBrowser/#/R-GGA-9933559 The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1 IEA Gallus gallus A0A1D5PEE5 R-GGA-9933575 https://reactome.org/PathwayBrowser/#/R-GGA-9933575 MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome IEA Gallus gallus A0A1D5PEE8 R-GGA-416683 https://reactome.org/PathwayBrowser/#/R-GGA-416683 SEMA3E binds to PLXND1 IEA Gallus gallus A0A1D5PEH0 R-GGA-1247497 https://reactome.org/PathwayBrowser/#/R-GGA-1247497 ERBB3 binds neuregulins IEA Gallus gallus A0A1D5PEH0 R-GGA-1250189 https://reactome.org/PathwayBrowser/#/R-GGA-1250189 Binding of PI3K to ERBB2:p-ERBB3 heterodimer IEA Gallus gallus A0A1D5PEH0 R-GGA-1250195 https://reactome.org/PathwayBrowser/#/R-GGA-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Gallus gallus A0A1D5PEH0 R-GGA-1250462 https://reactome.org/PathwayBrowser/#/R-GGA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Gallus gallus A0A1D5PEH0 R-GGA-1358790 https://reactome.org/PathwayBrowser/#/R-GGA-1358790 RNF41 ubiquitinates ERBB3 IEA Gallus gallus A0A1D5PEH0 R-GGA-1358792 https://reactome.org/PathwayBrowser/#/R-GGA-1358792 RNF41 ubiquitinates activated ERBB3 IEA Gallus gallus A0A1D5PEH0 R-GGA-1358798 https://reactome.org/PathwayBrowser/#/R-GGA-1358798 RNF41 binds neuregulin-activated ERBB3 IEA Gallus gallus A0A1D5PEH0 R-GGA-1358801 https://reactome.org/PathwayBrowser/#/R-GGA-1358801 ERBB3 binds RNF41 ubiquitin ligase IEA Gallus gallus A0A1D5PEH0 R-GGA-1963563 https://reactome.org/PathwayBrowser/#/R-GGA-1963563 MATK (CSK homologous kinase) binds phosphorylated ERBB2 IEA Gallus gallus A0A1D5PEH0 R-GGA-1963581 https://reactome.org/PathwayBrowser/#/R-GGA-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Gallus gallus A0A1D5PEH0 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus A0A1D5PEH0 R-GGA-1963586 https://reactome.org/PathwayBrowser/#/R-GGA-1963586 SRC family kinases phosphorylate ERBB2 IEA Gallus gallus A0A1D5PEH0 R-GGA-1977958 https://reactome.org/PathwayBrowser/#/R-GGA-1977958 ERBB4 forms heterodimers with ERBB3 IEA Gallus gallus A0A1D5PEH0 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PEH0 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5PEH0 R-GGA-6785636 https://reactome.org/PathwayBrowser/#/R-GGA-6785636 Phosphorylated ERBB2 heterodimers bind MEMO1 IEA Gallus gallus A0A1D5PEH0 R-GGA-8863804 https://reactome.org/PathwayBrowser/#/R-GGA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Gallus gallus A0A1D5PEH3 R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus A0A1D5PEH3 R-GGA-204169 https://reactome.org/PathwayBrowser/#/R-GGA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Gallus gallus A0A1D5PEH3 R-GGA-9861616 https://reactome.org/PathwayBrowser/#/R-GGA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus A0A1D5PEH3 R-GGA-9861667 https://reactome.org/PathwayBrowser/#/R-GGA-9861667 DLAT trimer transfers acetyl to CoA IEA Gallus gallus A0A1D5PEH3 R-GGA-9861734 https://reactome.org/PathwayBrowser/#/R-GGA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Gallus gallus A0A1D5PEH5 R-GGA-9018758 https://reactome.org/PathwayBrowser/#/R-GGA-9018758 RHOH binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PEH7 R-GGA-159425 https://reactome.org/PathwayBrowser/#/R-GGA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus A0A1D5PEH7 R-GGA-192137 https://reactome.org/PathwayBrowser/#/R-GGA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus A0A1D5PEH7 R-GGA-193401 https://reactome.org/PathwayBrowser/#/R-GGA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus A0A1D5PEH7 R-GGA-193407 https://reactome.org/PathwayBrowser/#/R-GGA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus A0A1D5PEH7 R-GGA-193424 https://reactome.org/PathwayBrowser/#/R-GGA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus A0A1D5PEH7 R-GGA-193711 https://reactome.org/PathwayBrowser/#/R-GGA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus A0A1D5PEH7 R-GGA-193727 https://reactome.org/PathwayBrowser/#/R-GGA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus A0A1D5PEH7 R-GGA-193743 https://reactome.org/PathwayBrowser/#/R-GGA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus A0A1D5PEH7 R-GGA-193766 https://reactome.org/PathwayBrowser/#/R-GGA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus A0A1D5PEH7 R-GGA-389622 https://reactome.org/PathwayBrowser/#/R-GGA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate IEA Gallus gallus A0A1D5PEH7 R-GGA-389632 https://reactome.org/PathwayBrowser/#/R-GGA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate IEA Gallus gallus A0A1D5PEH7 R-GGA-6799350 https://reactome.org/PathwayBrowser/#/R-GGA-6799350 Exocytosis of specific granule membrane proteins IEA Gallus gallus A0A1D5PEH7 R-GGA-9033235 https://reactome.org/PathwayBrowser/#/R-GGA-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1D5PEH7 R-GGA-9033236 https://reactome.org/PathwayBrowser/#/R-GGA-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Gallus gallus A0A1D5PEH7 R-GGA-9734535 https://reactome.org/PathwayBrowser/#/R-GGA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Gallus gallus A0A1D5PEH7 R-GGA-9914143 https://reactome.org/PathwayBrowser/#/R-GGA-9914143 SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH IEA Gallus gallus A0A1D5PEI0 R-GGA-109638 https://reactome.org/PathwayBrowser/#/R-GGA-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Gallus gallus A0A1D5PEI0 R-GGA-109639 https://reactome.org/PathwayBrowser/#/R-GGA-109639 Formation of the closed pre-initiation complex IEA Gallus gallus A0A1D5PEI0 R-GGA-111264 https://reactome.org/PathwayBrowser/#/R-GGA-111264 Addition of nucleotides between position +11 and +30 IEA Gallus gallus A0A1D5PEI0 R-GGA-112381 https://reactome.org/PathwayBrowser/#/R-GGA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Gallus gallus A0A1D5PEI0 R-GGA-112383 https://reactome.org/PathwayBrowser/#/R-GGA-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Gallus gallus A0A1D5PEI0 R-GGA-112385 https://reactome.org/PathwayBrowser/#/R-GGA-112385 Addition of nucleotides leads to transcript elongation IEA Gallus gallus A0A1D5PEI0 R-GGA-112392 https://reactome.org/PathwayBrowser/#/R-GGA-112392 Resumption of elongation after recovery from pausing IEA Gallus gallus A0A1D5PEI0 R-GGA-112395 https://reactome.org/PathwayBrowser/#/R-GGA-112395 Abortive termination of elongation after arrest IEA Gallus gallus A0A1D5PEI0 R-GGA-112396 https://reactome.org/PathwayBrowser/#/R-GGA-112396 Separation of elongating transcript from template IEA Gallus gallus A0A1D5PEI0 R-GGA-113402 https://reactome.org/PathwayBrowser/#/R-GGA-113402 Formation of DSIF:NELF:early elongation complex IEA Gallus gallus A0A1D5PEI0 R-GGA-113409 https://reactome.org/PathwayBrowser/#/R-GGA-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Gallus gallus A0A1D5PEI0 R-GGA-113411 https://reactome.org/PathwayBrowser/#/R-GGA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Gallus gallus A0A1D5PEI0 R-GGA-113412 https://reactome.org/PathwayBrowser/#/R-GGA-113412 Pol II elongation complex moves on the template as transcript elongates IEA Gallus gallus A0A1D5PEI0 R-GGA-113413 https://reactome.org/PathwayBrowser/#/R-GGA-113413 TFIIS-mediated recovery of elongation from arrest IEA Gallus gallus A0A1D5PEI0 R-GGA-113414 https://reactome.org/PathwayBrowser/#/R-GGA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Gallus gallus A0A1D5PEI0 R-GGA-113430 https://reactome.org/PathwayBrowser/#/R-GGA-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Gallus gallus A0A1D5PEI0 R-GGA-5578742 https://reactome.org/PathwayBrowser/#/R-GGA-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Gallus gallus A0A1D5PEI0 R-GGA-6781818 https://reactome.org/PathwayBrowser/#/R-GGA-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Gallus gallus A0A1D5PEI0 R-GGA-6781824 https://reactome.org/PathwayBrowser/#/R-GGA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Gallus gallus A0A1D5PEI0 R-GGA-6781833 https://reactome.org/PathwayBrowser/#/R-GGA-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Gallus gallus A0A1D5PEI0 R-GGA-6781840 https://reactome.org/PathwayBrowser/#/R-GGA-6781840 ERCC6 binds stalled RNA Pol II IEA Gallus gallus A0A1D5PEI0 R-GGA-6781867 https://reactome.org/PathwayBrowser/#/R-GGA-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Gallus gallus A0A1D5PEI0 R-GGA-6782069 https://reactome.org/PathwayBrowser/#/R-GGA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Gallus gallus A0A1D5PEI0 R-GGA-6782131 https://reactome.org/PathwayBrowser/#/R-GGA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5PEI0 R-GGA-6782138 https://reactome.org/PathwayBrowser/#/R-GGA-6782138 ERCC5 and RPA bind TC-NER site IEA Gallus gallus A0A1D5PEI0 R-GGA-6782204 https://reactome.org/PathwayBrowser/#/R-GGA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Gallus gallus A0A1D5PEI0 R-GGA-6782208 https://reactome.org/PathwayBrowser/#/R-GGA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Gallus gallus A0A1D5PEI0 R-GGA-6782211 https://reactome.org/PathwayBrowser/#/R-GGA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Gallus gallus A0A1D5PEI0 R-GGA-6782227 https://reactome.org/PathwayBrowser/#/R-GGA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Gallus gallus A0A1D5PEI0 R-GGA-6797606 https://reactome.org/PathwayBrowser/#/R-GGA-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Gallus gallus A0A1D5PEI0 R-GGA-6797616 https://reactome.org/PathwayBrowser/#/R-GGA-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Gallus gallus A0A1D5PEI0 R-GGA-6803523 https://reactome.org/PathwayBrowser/#/R-GGA-6803523 PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA IEA Gallus gallus A0A1D5PEI0 R-GGA-6810233 https://reactome.org/PathwayBrowser/#/R-GGA-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Gallus gallus A0A1D5PEI0 R-GGA-6810235 https://reactome.org/PathwayBrowser/#/R-GGA-6810235 RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain IEA Gallus gallus A0A1D5PEI0 R-GGA-6810238 https://reactome.org/PathwayBrowser/#/R-GGA-6810238 RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) IEA Gallus gallus A0A1D5PEI0 R-GGA-6814555 https://reactome.org/PathwayBrowser/#/R-GGA-6814555 Integrator complex processes the 3' end of snRNA IEA Gallus gallus A0A1D5PEI0 R-GGA-6814559 https://reactome.org/PathwayBrowser/#/R-GGA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Gallus gallus A0A1D5PEI0 R-GGA-72095 https://reactome.org/PathwayBrowser/#/R-GGA-72095 Internal Methylation of mRNA IEA Gallus gallus A0A1D5PEI0 R-GGA-72103 https://reactome.org/PathwayBrowser/#/R-GGA-72103 Formation of pre-mRNPs IEA Gallus gallus A0A1D5PEI0 R-GGA-73946 https://reactome.org/PathwayBrowser/#/R-GGA-73946 Abortive initiation after formation of the first phosphodiester bond IEA Gallus gallus A0A1D5PEI0 R-GGA-75079 https://reactome.org/PathwayBrowser/#/R-GGA-75079 Formation of AT-AC C complex IEA Gallus gallus A0A1D5PEI0 R-GGA-75081 https://reactome.org/PathwayBrowser/#/R-GGA-75081 Formation of AT-AC B Complex IEA Gallus gallus A0A1D5PEI0 R-GGA-75082 https://reactome.org/PathwayBrowser/#/R-GGA-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Gallus gallus A0A1D5PEI0 R-GGA-75083 https://reactome.org/PathwayBrowser/#/R-GGA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Gallus gallus A0A1D5PEI0 R-GGA-75095 https://reactome.org/PathwayBrowser/#/R-GGA-75095 Binding of TFIIE to the growing preinitiation complex IEA Gallus gallus A0A1D5PEI0 R-GGA-75850 https://reactome.org/PathwayBrowser/#/R-GGA-75850 Addition of the third nucleotide on the nascent transcript IEA Gallus gallus A0A1D5PEI0 R-GGA-75856 https://reactome.org/PathwayBrowser/#/R-GGA-75856 Abortive Initiation Before Second Transition IEA Gallus gallus A0A1D5PEI0 R-GGA-75861 https://reactome.org/PathwayBrowser/#/R-GGA-75861 NTP Binds Active Site of RNA Polymerase II IEA Gallus gallus A0A1D5PEI0 R-GGA-75862 https://reactome.org/PathwayBrowser/#/R-GGA-75862 Fall Back to Closed Pre-initiation Complex IEA Gallus gallus A0A1D5PEI0 R-GGA-75864 https://reactome.org/PathwayBrowser/#/R-GGA-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Gallus gallus A0A1D5PEI0 R-GGA-75866 https://reactome.org/PathwayBrowser/#/R-GGA-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Gallus gallus A0A1D5PEI0 R-GGA-75869 https://reactome.org/PathwayBrowser/#/R-GGA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Gallus gallus A0A1D5PEI0 R-GGA-75873 https://reactome.org/PathwayBrowser/#/R-GGA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Gallus gallus A0A1D5PEI0 R-GGA-75891 https://reactome.org/PathwayBrowser/#/R-GGA-75891 Abortive Initiation After Second Transition IEA Gallus gallus A0A1D5PEI0 R-GGA-75949 https://reactome.org/PathwayBrowser/#/R-GGA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Gallus gallus A0A1D5PEI0 R-GGA-76576 https://reactome.org/PathwayBrowser/#/R-GGA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Gallus gallus A0A1D5PEI0 R-GGA-77068 https://reactome.org/PathwayBrowser/#/R-GGA-77068 Activation of GT IEA Gallus gallus A0A1D5PEI0 R-GGA-77069 https://reactome.org/PathwayBrowser/#/R-GGA-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Gallus gallus A0A1D5PEI0 R-GGA-77071 https://reactome.org/PathwayBrowser/#/R-GGA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Gallus gallus A0A1D5PEI0 R-GGA-77077 https://reactome.org/PathwayBrowser/#/R-GGA-77077 Capping complex formation IEA Gallus gallus A0A1D5PEI0 R-GGA-77078 https://reactome.org/PathwayBrowser/#/R-GGA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Gallus gallus A0A1D5PEI0 R-GGA-77081 https://reactome.org/PathwayBrowser/#/R-GGA-77081 Formation of the CE:GMP intermediate complex IEA Gallus gallus A0A1D5PEI0 R-GGA-77083 https://reactome.org/PathwayBrowser/#/R-GGA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Gallus gallus A0A1D5PEI0 R-GGA-77085 https://reactome.org/PathwayBrowser/#/R-GGA-77085 Dissociation of transcript with 5'-GMP from GT IEA Gallus gallus A0A1D5PEI0 R-GGA-77095 https://reactome.org/PathwayBrowser/#/R-GGA-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Gallus gallus A0A1D5PEI0 R-GGA-9012315 https://reactome.org/PathwayBrowser/#/R-GGA-9012315 ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene IEA Gallus gallus A0A1D5PEI0 R-GGA-9012319 https://reactome.org/PathwayBrowser/#/R-GGA-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Gallus gallus A0A1D5PEI0 R-GGA-9613494 https://reactome.org/PathwayBrowser/#/R-GGA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Gallus gallus A0A1D5PEI0 R-GGA-9613497 https://reactome.org/PathwayBrowser/#/R-GGA-9613497 Unwinding DNA for the nascent transcript IEA Gallus gallus A0A1D5PEI0 R-GGA-9684118 https://reactome.org/PathwayBrowser/#/R-GGA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5PEI0 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5PEI3 R-GGA-1022133 https://reactome.org/PathwayBrowser/#/R-GGA-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Gallus gallus A0A1D5PEI3 R-GGA-4084978 https://reactome.org/PathwayBrowser/#/R-GGA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Gallus gallus A0A1D5PEI5 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5PEI5 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5PEI5 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5PEI5 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5PEI5 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5PEI5 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus A0A1D5PEI5 R-GGA-5624949 https://reactome.org/PathwayBrowser/#/R-GGA-5624949 Assembly of the anterograde IFT train IEA Gallus gallus A0A1D5PEI5 R-GGA-5625416 https://reactome.org/PathwayBrowser/#/R-GGA-5625416 Anterograde IFT IEA Gallus gallus A0A1D5PEI5 R-GGA-5625426 https://reactome.org/PathwayBrowser/#/R-GGA-5625426 Retrograde IFT IEA Gallus gallus A0A1D5PEI5 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1D5PEI5 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5PEI5 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5PEI5 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5PEI5 R-GGA-8849350 https://reactome.org/PathwayBrowser/#/R-GGA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Gallus gallus A0A1D5PEI5 R-GGA-8849353 https://reactome.org/PathwayBrowser/#/R-GGA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Gallus gallus A0A1D5PEI5 R-GGA-9646679 https://reactome.org/PathwayBrowser/#/R-GGA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Gallus gallus A0A1D5PEI5 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1D5PEI5 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus A0A1D5PEK3 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PEK7 R-GGA-432049 https://reactome.org/PathwayBrowser/#/R-GGA-432049 Aquaporin-9 passively transports glycerol into cell IEA Gallus gallus A0A1D5PEK7 R-GGA-507868 https://reactome.org/PathwayBrowser/#/R-GGA-507868 Aquaporins passively transport water into cells IEA Gallus gallus A0A1D5PEK7 R-GGA-507869 https://reactome.org/PathwayBrowser/#/R-GGA-507869 Aquaporins passively transport glycerol into cells IEA Gallus gallus A0A1D5PEK7 R-GGA-507870 https://reactome.org/PathwayBrowser/#/R-GGA-507870 Aquaporins passively transport water out of cells IEA Gallus gallus A0A1D5PEK7 R-GGA-507871 https://reactome.org/PathwayBrowser/#/R-GGA-507871 Aquaporins passively transport glycerol out of cells IEA Gallus gallus A0A1D5PEK7 R-GGA-507873 https://reactome.org/PathwayBrowser/#/R-GGA-507873 Aquaporins passively transport urea out of cells IEA Gallus gallus A0A1D5PEK7 R-GGA-507875 https://reactome.org/PathwayBrowser/#/R-GGA-507875 Aquaporins passively transport urea into cells IEA Gallus gallus A0A1D5PEM4 R-GGA-445699 https://reactome.org/PathwayBrowser/#/R-GGA-445699 ATP Hydrolysis By Myosin IEA Gallus gallus A0A1D5PEM4 R-GGA-445700 https://reactome.org/PathwayBrowser/#/R-GGA-445700 Myosin Binds ATP IEA Gallus gallus A0A1D5PEM4 R-GGA-445704 https://reactome.org/PathwayBrowser/#/R-GGA-445704 Calcium Binds Caldesmon IEA Gallus gallus A0A1D5PEM4 R-GGA-445705 https://reactome.org/PathwayBrowser/#/R-GGA-445705 Release Of ADP From Myosin IEA Gallus gallus A0A1D5PEM4 R-GGA-445813 https://reactome.org/PathwayBrowser/#/R-GGA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Gallus gallus A0A1D5PEM4 R-GGA-5668932 https://reactome.org/PathwayBrowser/#/R-GGA-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Gallus gallus A0A1D5PEM8 R-GGA-6809764 https://reactome.org/PathwayBrowser/#/R-GGA-6809764 SBF1 binds MTMR2 IEA Gallus gallus A0A1D5PEM8 R-GGA-6809777 https://reactome.org/PathwayBrowser/#/R-GGA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Gallus gallus A0A1D5PEM8 R-GGA-6809778 https://reactome.org/PathwayBrowser/#/R-GGA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Gallus gallus A0A1D5PEM8 R-GGA-8876837 https://reactome.org/PathwayBrowser/#/R-GGA-8876837 RAB21 GEFs exchange GTP for GDP on RAB21 IEA Gallus gallus A0A1D5PEN8 R-GGA-1667005 https://reactome.org/PathwayBrowser/#/R-GGA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Gallus gallus A0A1D5PEN8 R-GGA-1678694 https://reactome.org/PathwayBrowser/#/R-GGA-1678694 Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans IEA Gallus gallus A0A1D5PEN8 R-GGA-1878002 https://reactome.org/PathwayBrowser/#/R-GGA-1878002 XYLTs transfer Xyl to core protein IEA Gallus gallus A0A1D5PEN8 R-GGA-1889955 https://reactome.org/PathwayBrowser/#/R-GGA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Gallus gallus A0A1D5PEN8 R-GGA-1889981 https://reactome.org/PathwayBrowser/#/R-GGA-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Gallus gallus A0A1D5PEN8 R-GGA-2022860 https://reactome.org/PathwayBrowser/#/R-GGA-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Gallus gallus A0A1D5PEN8 R-GGA-2022887 https://reactome.org/PathwayBrowser/#/R-GGA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Gallus gallus A0A1D5PEN8 R-GGA-2024084 https://reactome.org/PathwayBrowser/#/R-GGA-2024084 HS-GAGs translocate to the lysosome for degradation IEA Gallus gallus A0A1D5PEN8 R-GGA-2024108 https://reactome.org/PathwayBrowser/#/R-GGA-2024108 Some HSPGs are secreted to the plasma membrane IEA Gallus gallus A0A1D5PEN8 R-GGA-2076383 https://reactome.org/PathwayBrowser/#/R-GGA-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Gallus gallus A0A1D5PEN8 R-GGA-2076419 https://reactome.org/PathwayBrowser/#/R-GGA-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Gallus gallus A0A1D5PEN8 R-GGA-2076508 https://reactome.org/PathwayBrowser/#/R-GGA-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Gallus gallus A0A1D5PEN8 R-GGA-2076611 https://reactome.org/PathwayBrowser/#/R-GGA-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Gallus gallus A0A1D5PEN8 R-GGA-2684507 https://reactome.org/PathwayBrowser/#/R-GGA-2684507 Syndecans 1, 2, 4, (3) bind FGF2 IEA Gallus gallus A0A1D5PEN8 R-GGA-2731122 https://reactome.org/PathwayBrowser/#/R-GGA-2731122 Syndecans 1, 2 & 4 bind VTN IEA Gallus gallus A0A1D5PEP3 R-GGA-8854604 https://reactome.org/PathwayBrowser/#/R-GGA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Gallus gallus A0A1D5PEQ5 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus A0A1D5PEQ5 R-GGA-9013022 https://reactome.org/PathwayBrowser/#/R-GGA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Gallus gallus A0A1D5PEQ5 R-GGA-9013111 https://reactome.org/PathwayBrowser/#/R-GGA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Gallus gallus A0A1D5PEQ5 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus A0A1D5PEQ5 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus A0A1D5PEQ5 R-GGA-9018745 https://reactome.org/PathwayBrowser/#/R-GGA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Gallus gallus A0A1D5PER1 R-GGA-6805205 https://reactome.org/PathwayBrowser/#/R-GGA-6805205 GPR35 binds kynurenic acid IEA Gallus gallus A0A1D5PER3 R-GGA-3229089 https://reactome.org/PathwayBrowser/#/R-GGA-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Gallus gallus A0A1D5PER3 R-GGA-3229102 https://reactome.org/PathwayBrowser/#/R-GGA-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Gallus gallus A0A1D5PER3 R-GGA-8937989 https://reactome.org/PathwayBrowser/#/R-GGA-8937989 RUNX1 binds PRC1 complexes IEA Gallus gallus A0A1D5PER3 R-GGA-8943817 https://reactome.org/PathwayBrowser/#/R-GGA-8943817 MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter IEA Gallus gallus A0A1D5PET1 R-GGA-1632857 https://reactome.org/PathwayBrowser/#/R-GGA-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Gallus gallus A0A1D5PET1 R-GGA-1675939 https://reactome.org/PathwayBrowser/#/R-GGA-1675939 PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane IEA Gallus gallus A0A1D5PET1 R-GGA-1675961 https://reactome.org/PathwayBrowser/#/R-GGA-1675961 PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane IEA Gallus gallus A0A1D5PET1 R-GGA-1676024 https://reactome.org/PathwayBrowser/#/R-GGA-1676024 PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane IEA Gallus gallus A0A1D5PET1 R-GGA-5672012 https://reactome.org/PathwayBrowser/#/R-GGA-5672012 Beclin-1 complex phosphorylates PtdIns IEA Gallus gallus A0A1D5PET1 R-GGA-5679205 https://reactome.org/PathwayBrowser/#/R-GGA-5679205 ULK1 phosphorylates Beclin-1 IEA Gallus gallus A0A1D5PET1 R-GGA-5679266 https://reactome.org/PathwayBrowser/#/R-GGA-5679266 Beclin-1 complex translocates to the ER IEA Gallus gallus A0A1D5PET1 R-GGA-5682385 https://reactome.org/PathwayBrowser/#/R-GGA-5682385 The phagophore extends from the PIP3-enriched structure IEA Gallus gallus A0A1D5PET1 R-GGA-5682388 https://reactome.org/PathwayBrowser/#/R-GGA-5682388 Autophagosome maturation IEA Gallus gallus A0A1D5PET1 R-GGA-6798174 https://reactome.org/PathwayBrowser/#/R-GGA-6798174 PIK3C3:PIK3R4 phosphorylates PI to PI3P IEA Gallus gallus A0A1D5PET9 R-GGA-448958 https://reactome.org/PathwayBrowser/#/R-GGA-448958 Nuclear translocation of p38 MAPK IEA Gallus gallus A0A1D5PEU0 R-GGA-917696 https://reactome.org/PathwayBrowser/#/R-GGA-917696 Cargo Sequestration IEA Gallus gallus A0A1D5PEU0 R-GGA-917730 https://reactome.org/PathwayBrowser/#/R-GGA-917730 Cargo Recognition And Sorting IEA Gallus gallus A0A1D5PEU8 R-GGA-8866277 https://reactome.org/PathwayBrowser/#/R-GGA-8866277 AP-2 directly binds some endocytic cargo IEA Gallus gallus A0A1D5PEU8 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5PEU8 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5PEU8 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5PEU8 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5PEU8 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5PEU8 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5PEU8 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5PEU8 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5PEU8 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PEU8 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PEU8 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5PEU8 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5PEV3 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PEV3 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5PEV3 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus A0A1D5PEV3 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus A0A1D5PEV3 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus A0A1D5PEV4 R-GGA-1614362 https://reactome.org/PathwayBrowser/#/R-GGA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Gallus gallus A0A1D5PEW1 R-GGA-430311 https://reactome.org/PathwayBrowser/#/R-GGA-430311 Rsu-1 interacts with Pinch1 IEA Gallus gallus A0A1D5PEX8 R-GGA-74986 https://reactome.org/PathwayBrowser/#/R-GGA-74986 Elongation of pre-rRNA transcript IEA Gallus gallus A0A1D5PEX8 R-GGA-9007283 https://reactome.org/PathwayBrowser/#/R-GGA-9007283 CBX3 and PRC1.6 associate with E2F6.com-1 IEA Gallus gallus A0A1D5PEX8 R-GGA-9007447 https://reactome.org/PathwayBrowser/#/R-GGA-9007447 E2F6 forms the PRC1L4 complex IEA Gallus gallus A0A1D5PEY1 R-GGA-9933559 https://reactome.org/PathwayBrowser/#/R-GGA-9933559 The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1 IEA Gallus gallus A0A1D5PEY1 R-GGA-9933575 https://reactome.org/PathwayBrowser/#/R-GGA-9933575 MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome IEA Gallus gallus A0A1D5PEY3 R-GGA-429955 https://reactome.org/PathwayBrowser/#/R-GGA-429955 CCR4-NOT complex deadenylates mRNA IEA Gallus gallus A0A1D5PEY3 R-GGA-6798044 https://reactome.org/PathwayBrowser/#/R-GGA-6798044 BTG2 binds CCR4-NOT complex IEA Gallus gallus A0A1D5PEY8 R-GGA-173709 https://reactome.org/PathwayBrowser/#/R-GGA-173709 C7 binds C5b:C6 IEA Gallus gallus A0A1D5PEY8 R-GGA-173720 https://reactome.org/PathwayBrowser/#/R-GGA-173720 C5b:C6:C7 translocates to the plasma membrane IEA Gallus gallus A0A1D5PEY8 R-GGA-173723 https://reactome.org/PathwayBrowser/#/R-GGA-173723 C8 binds C5b:C6:C7 IEA Gallus gallus A0A1D5PEZ2 R-GGA-109813 https://reactome.org/PathwayBrowser/#/R-GGA-109813 GRB2-1 binds SOS1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-1112666 https://reactome.org/PathwayBrowser/#/R-GGA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Gallus gallus A0A1D5PEZ2 R-GGA-1250380 https://reactome.org/PathwayBrowser/#/R-GGA-1250380 Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers IEA Gallus gallus A0A1D5PEZ2 R-GGA-1250383 https://reactome.org/PathwayBrowser/#/R-GGA-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Gallus gallus A0A1D5PEZ2 R-GGA-1306969 https://reactome.org/PathwayBrowser/#/R-GGA-1306969 GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers IEA Gallus gallus A0A1D5PEZ2 R-GGA-1306972 https://reactome.org/PathwayBrowser/#/R-GGA-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Gallus gallus A0A1D5PEZ2 R-GGA-1433471 https://reactome.org/PathwayBrowser/#/R-GGA-1433471 Activation of RAS by p-KIT bound SOS1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-177936 https://reactome.org/PathwayBrowser/#/R-GGA-177936 GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR IEA Gallus gallus A0A1D5PEZ2 R-GGA-177938 https://reactome.org/PathwayBrowser/#/R-GGA-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Gallus gallus A0A1D5PEZ2 R-GGA-177943 https://reactome.org/PathwayBrowser/#/R-GGA-177943 GRB2:SOS1 complex binds to EGF:EGFR complex IEA Gallus gallus A0A1D5PEZ2 R-GGA-177945 https://reactome.org/PathwayBrowser/#/R-GGA-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Gallus gallus A0A1D5PEZ2 R-GGA-186826 https://reactome.org/PathwayBrowser/#/R-GGA-186826 GRB2:SOS1 complex binds to the active receptor IEA Gallus gallus A0A1D5PEZ2 R-GGA-186834 https://reactome.org/PathwayBrowser/#/R-GGA-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Gallus gallus A0A1D5PEZ2 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus A0A1D5PEZ2 R-GGA-205244 https://reactome.org/PathwayBrowser/#/R-GGA-205244 Recruitment of CBL to KIT IEA Gallus gallus A0A1D5PEZ2 R-GGA-205286 https://reactome.org/PathwayBrowser/#/R-GGA-205286 GRB2:SOS interacts with p-KIT IEA Gallus gallus A0A1D5PEZ2 R-GGA-210974 https://reactome.org/PathwayBrowser/#/R-GGA-210974 Interaction of SOS-1 to Tie2 bound Grb2 IEA Gallus gallus A0A1D5PEZ2 R-GGA-210977 https://reactome.org/PathwayBrowser/#/R-GGA-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Gallus gallus A0A1D5PEZ2 R-GGA-2179407 https://reactome.org/PathwayBrowser/#/R-GGA-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Gallus gallus A0A1D5PEZ2 R-GGA-2179415 https://reactome.org/PathwayBrowser/#/R-GGA-2179415 GRB2:SOS1 binds to HBEGF:p-Y-EGFR IEA Gallus gallus A0A1D5PEZ2 R-GGA-2396561 https://reactome.org/PathwayBrowser/#/R-GGA-2396561 Recruitment of GADS:SLP-76 to p-5Y-LAT IEA Gallus gallus A0A1D5PEZ2 R-GGA-2396594 https://reactome.org/PathwayBrowser/#/R-GGA-2396594 Phosphorylation of SLP-76 by p-SYK IEA Gallus gallus A0A1D5PEZ2 R-GGA-2396606 https://reactome.org/PathwayBrowser/#/R-GGA-2396606 Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT IEA Gallus gallus A0A1D5PEZ2 R-GGA-2424476 https://reactome.org/PathwayBrowser/#/R-GGA-2424476 Activation of RAC1 by VAV2/3 IEA Gallus gallus A0A1D5PEZ2 R-GGA-2424477 https://reactome.org/PathwayBrowser/#/R-GGA-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Gallus gallus A0A1D5PEZ2 R-GGA-2424481 https://reactome.org/PathwayBrowser/#/R-GGA-2424481 Recruitment of VAV and BTK to p-SLP-76 IEA Gallus gallus A0A1D5PEZ2 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus A0A1D5PEZ2 R-GGA-2424485 https://reactome.org/PathwayBrowser/#/R-GGA-2424485 Release of p-PLCG1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus A0A1D5PEZ2 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus A0A1D5PEZ2 R-GGA-2730837 https://reactome.org/PathwayBrowser/#/R-GGA-2730837 Recruitment of GRB2:SOS to p-10Y-NTAL IEA Gallus gallus A0A1D5PEZ2 R-GGA-2730840 https://reactome.org/PathwayBrowser/#/R-GGA-2730840 Activation of RAC1 by VAV IEA Gallus gallus A0A1D5PEZ2 R-GGA-2730841 https://reactome.org/PathwayBrowser/#/R-GGA-2730841 Phosphorylation and activation of VAV IEA Gallus gallus A0A1D5PEZ2 R-GGA-2730842 https://reactome.org/PathwayBrowser/#/R-GGA-2730842 PI3K associates with phosphorylated GAB2 IEA Gallus gallus A0A1D5PEZ2 R-GGA-2730844 https://reactome.org/PathwayBrowser/#/R-GGA-2730844 Interaction of GRB2:SOS complex with p-SHC1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-2730847 https://reactome.org/PathwayBrowser/#/R-GGA-2730847 Hydrolysis of PIP2 by PLCG IEA Gallus gallus A0A1D5PEZ2 R-GGA-2730856 https://reactome.org/PathwayBrowser/#/R-GGA-2730856 Autophosphorylation of PAK IEA Gallus gallus A0A1D5PEZ2 R-GGA-2730858 https://reactome.org/PathwayBrowser/#/R-GGA-2730858 Autophosphorylation of BTK/ITK IEA Gallus gallus A0A1D5PEZ2 R-GGA-2730870 https://reactome.org/PathwayBrowser/#/R-GGA-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Gallus gallus A0A1D5PEZ2 R-GGA-2730889 https://reactome.org/PathwayBrowser/#/R-GGA-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-2730892 https://reactome.org/PathwayBrowser/#/R-GGA-2730892 Recruitment of VAV to p-SLP-76 IEA Gallus gallus A0A1D5PEZ2 R-GGA-354165 https://reactome.org/PathwayBrowser/#/R-GGA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-392053 https://reactome.org/PathwayBrowser/#/R-GGA-392053 SOS binds Grb2 bound to pFAK:NCAM1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-392054 https://reactome.org/PathwayBrowser/#/R-GGA-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Gallus gallus A0A1D5PEZ2 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus A0A1D5PEZ2 R-GGA-453111 https://reactome.org/PathwayBrowser/#/R-GGA-453111 Phosphorylated SHC recruits GRB2:SOS1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-5654392 https://reactome.org/PathwayBrowser/#/R-GGA-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PEZ2 R-GGA-5654402 https://reactome.org/PathwayBrowser/#/R-GGA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PEZ2 R-GGA-5654406 https://reactome.org/PathwayBrowser/#/R-GGA-5654406 Activated FGFR2:p-SHC1 binds GRB2:SOS1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-5654413 https://reactome.org/PathwayBrowser/#/R-GGA-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PEZ2 R-GGA-5654416 https://reactome.org/PathwayBrowser/#/R-GGA-5654416 Activated FGFR3:pFRS binds GRB2:SOS1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-5654423 https://reactome.org/PathwayBrowser/#/R-GGA-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-5654426 https://reactome.org/PathwayBrowser/#/R-GGA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PEZ2 R-GGA-5654586 https://reactome.org/PathwayBrowser/#/R-GGA-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-5654597 https://reactome.org/PathwayBrowser/#/R-GGA-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-5654600 https://reactome.org/PathwayBrowser/#/R-GGA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PEZ2 R-GGA-5654615 https://reactome.org/PathwayBrowser/#/R-GGA-5654615 Activated FGFR2:pFRS binds GRB2:SOS1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-5654618 https://reactome.org/PathwayBrowser/#/R-GGA-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PEZ2 R-GGA-5654646 https://reactome.org/PathwayBrowser/#/R-GGA-5654646 Activated FGFR3:p-SHC1 binds GRB2:SOS1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-5654647 https://reactome.org/PathwayBrowser/#/R-GGA-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PEZ2 R-GGA-5654663 https://reactome.org/PathwayBrowser/#/R-GGA-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PEZ2 R-GGA-5654664 https://reactome.org/PathwayBrowser/#/R-GGA-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5PEZ2 R-GGA-5685366 https://reactome.org/PathwayBrowser/#/R-GGA-5685366 GRB2-1:SOS1 binds p-Y-SHC IEA Gallus gallus A0A1D5PEZ2 R-GGA-5686073 https://reactome.org/PathwayBrowser/#/R-GGA-5686073 GRB2-1:SOS1 binds p-3Y-SHC1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-5686074 https://reactome.org/PathwayBrowser/#/R-GGA-5686074 GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates IEA Gallus gallus A0A1D5PEZ2 R-GGA-5686315 https://reactome.org/PathwayBrowser/#/R-GGA-5686315 GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates IEA Gallus gallus A0A1D5PEZ2 R-GGA-74736 https://reactome.org/PathwayBrowser/#/R-GGA-74736 GRB2-1:SOS1 binds p-IRS1,p-IRS2 IEA Gallus gallus A0A1D5PEZ2 R-GGA-74746 https://reactome.org/PathwayBrowser/#/R-GGA-74746 GRB2-1:SOS1 binds p-Y427-SHC1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-8851804 https://reactome.org/PathwayBrowser/#/R-GGA-8851804 Activated MET recruits GRB2-1:SOS1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-8851827 https://reactome.org/PathwayBrowser/#/R-GGA-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-8851877 https://reactome.org/PathwayBrowser/#/R-GGA-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Gallus gallus A0A1D5PEZ2 R-GGA-8851899 https://reactome.org/PathwayBrowser/#/R-GGA-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Gallus gallus A0A1D5PEZ2 R-GGA-8851900 https://reactome.org/PathwayBrowser/#/R-GGA-8851900 SHC1-2 bound to MET recruits GRB2:SOS1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-8853734 https://reactome.org/PathwayBrowser/#/R-GGA-8853734 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-8854899 https://reactome.org/PathwayBrowser/#/R-GGA-8854899 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-8983384 https://reactome.org/PathwayBrowser/#/R-GGA-8983384 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 IEA Gallus gallus A0A1D5PEZ2 R-GGA-9013143 https://reactome.org/PathwayBrowser/#/R-GGA-9013143 RAC1 GEFs activate RAC1 IEA Gallus gallus A0A1D5PEZ2 R-GGA-9032073 https://reactome.org/PathwayBrowser/#/R-GGA-9032073 NTRK2-phosphorylated FRS2 binds GRB2 IEA Gallus gallus A0A1D5PEZ2 R-GGA-9607304 https://reactome.org/PathwayBrowser/#/R-GGA-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Gallus gallus A0A1D5PEZ2 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus A0A1D5PEZ2 R-GGA-983703 https://reactome.org/PathwayBrowser/#/R-GGA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Gallus gallus A0A1D5PEZ2 R-GGA-9842669 https://reactome.org/PathwayBrowser/#/R-GGA-9842669 Active LTK recruits GRB2:SOS1 IEA Gallus gallus A0A1D5PF08 R-GGA-901047 https://reactome.org/PathwayBrowser/#/R-GGA-901047 Binding of ERp57 IEA Gallus gallus A0A1D5PF08 R-GGA-983145 https://reactome.org/PathwayBrowser/#/R-GGA-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Gallus gallus A0A1D5PF08 R-GGA-983146 https://reactome.org/PathwayBrowser/#/R-GGA-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Gallus gallus A0A1D5PF37 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5PF37 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5PF37 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5PF37 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5PF37 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5PF84 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus A0A1D5PF84 R-GGA-388605 https://reactome.org/PathwayBrowser/#/R-GGA-388605 POMC(138-176) binds MC2R IEA Gallus gallus A0A1D5PF87 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PF87 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PF87 R-GGA-71552 https://reactome.org/PathwayBrowser/#/R-GGA-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin IEA Gallus gallus A0A1D5PF87 R-GGA-71593 https://reactome.org/PathwayBrowser/#/R-GGA-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Gallus gallus A0A1D5PF92 R-GGA-8952630 https://reactome.org/PathwayBrowser/#/R-GGA-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PF92 R-GGA-8952631 https://reactome.org/PathwayBrowser/#/R-GGA-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PF92 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5PF92 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5PF92 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PF92 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PF92 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PF92 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PF95 R-GGA-1483096 https://reactome.org/PathwayBrowser/#/R-GGA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Gallus gallus A0A1D5PF95 R-GGA-1483159 https://reactome.org/PathwayBrowser/#/R-GGA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Gallus gallus A0A1D5PFA5 R-GGA-445699 https://reactome.org/PathwayBrowser/#/R-GGA-445699 ATP Hydrolysis By Myosin IEA Gallus gallus A0A1D5PFA5 R-GGA-445700 https://reactome.org/PathwayBrowser/#/R-GGA-445700 Myosin Binds ATP IEA Gallus gallus A0A1D5PFA5 R-GGA-445704 https://reactome.org/PathwayBrowser/#/R-GGA-445704 Calcium Binds Caldesmon IEA Gallus gallus A0A1D5PFA5 R-GGA-445705 https://reactome.org/PathwayBrowser/#/R-GGA-445705 Release Of ADP From Myosin IEA Gallus gallus A0A1D5PFA5 R-GGA-445813 https://reactome.org/PathwayBrowser/#/R-GGA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Gallus gallus A0A1D5PFA7 R-GGA-2022381 https://reactome.org/PathwayBrowser/#/R-GGA-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus A0A1D5PFA7 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus A0A1D5PFA7 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus A0A1D5PFA7 R-GGA-432706 https://reactome.org/PathwayBrowser/#/R-GGA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Gallus gallus A0A1D5PFA7 R-GGA-432707 https://reactome.org/PathwayBrowser/#/R-GGA-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Gallus gallus A0A1D5PFA7 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus A0A1D5PFA7 R-GGA-5694417 https://reactome.org/PathwayBrowser/#/R-GGA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Gallus gallus A0A1D5PFA7 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus A0A1D5PFA7 R-GGA-5694428 https://reactome.org/PathwayBrowser/#/R-GGA-5694428 LMAN family proteins bind glycosylated cargo IEA Gallus gallus A0A1D5PFA7 R-GGA-5694446 https://reactome.org/PathwayBrowser/#/R-GGA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Gallus gallus A0A1D5PFA7 R-GGA-5694522 https://reactome.org/PathwayBrowser/#/R-GGA-5694522 Inner coat assembly and cargo binding IEA Gallus gallus A0A1D5PFA7 R-GGA-5694527 https://reactome.org/PathwayBrowser/#/R-GGA-5694527 Loss of SAR1B GTPase IEA Gallus gallus A0A1D5PFA7 R-GGA-6798749 https://reactome.org/PathwayBrowser/#/R-GGA-6798749 Exocytosis of specific granule lumen proteins IEA Gallus gallus A0A1D5PFA7 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PFA8 R-GGA-421831 https://reactome.org/PathwayBrowser/#/R-GGA-421831 trans-Golgi Network Coat Assembly IEA Gallus gallus A0A1D5PFA8 R-GGA-421835 https://reactome.org/PathwayBrowser/#/R-GGA-421835 trans-Golgi Network Vesicle Scission IEA Gallus gallus A0A1D5PFE0 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus A0A1D5PFE0 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus A0A1D5PFE0 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus A0A1D5PFE0 R-GGA-1981120 https://reactome.org/PathwayBrowser/#/R-GGA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Gallus gallus A0A1D5PFE0 R-GGA-2002460 https://reactome.org/PathwayBrowser/#/R-GGA-2002460 P4HB binds Collagen chains IEA Gallus gallus A0A1D5PFE0 R-GGA-2089971 https://reactome.org/PathwayBrowser/#/R-GGA-2089971 Secretion of collagens IEA Gallus gallus A0A1D5PFE0 R-GGA-2152276 https://reactome.org/PathwayBrowser/#/R-GGA-2152276 Secretion of transmembrane collagens IEA Gallus gallus A0A1D5PFE0 R-GGA-2471842 https://reactome.org/PathwayBrowser/#/R-GGA-2471842 Collagen type XXV ectomain shedding IEA Gallus gallus A0A1D5PFE0 R-GGA-8944250 https://reactome.org/PathwayBrowser/#/R-GGA-8944250 Association of procollagen type XXV IEA Gallus gallus A0A1D5PFE0 R-GGA-8944254 https://reactome.org/PathwayBrowser/#/R-GGA-8944254 Association of procollagen type XXVI IEA Gallus gallus A0A1D5PFE0 R-GGA-8948228 https://reactome.org/PathwayBrowser/#/R-GGA-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Gallus gallus A0A1D5PFE0 R-GGA-8948231 https://reactome.org/PathwayBrowser/#/R-GGA-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Gallus gallus A0A1D5PFE0 R-GGA-8948232 https://reactome.org/PathwayBrowser/#/R-GGA-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Gallus gallus A0A1D5PFE0 R-GGA-8948234 https://reactome.org/PathwayBrowser/#/R-GGA-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Gallus gallus A0A1D5PFE9 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1D5PFF3 R-GGA-5682826 https://reactome.org/PathwayBrowser/#/R-GGA-5682826 LGI1 binds ADAM11 IEA Gallus gallus A0A1D5PFG8 R-GGA-936564 https://reactome.org/PathwayBrowser/#/R-GGA-936564 NLRX1 inhibits MAVS-DDX58 interaction IEA Gallus gallus A0A1D5PFG8 R-GGA-9709842 https://reactome.org/PathwayBrowser/#/R-GGA-9709842 MAVS binds TOMM70 IEA Gallus gallus A0A1D5PFG8 R-GGA-9833777 https://reactome.org/PathwayBrowser/#/R-GGA-9833777 PKR binds activating host RNA IEA Gallus gallus A0A1D5PFI0 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PFI9 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus A0A1D5PFI9 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus A0A1D5PFJ6 R-GGA-3371422 https://reactome.org/PathwayBrowser/#/R-GGA-3371422 ATP hydrolysis by HSP70 IEA Gallus gallus A0A1D5PFJ6 R-GGA-3371467 https://reactome.org/PathwayBrowser/#/R-GGA-3371467 SIRT1 deacetylates HSF1 IEA Gallus gallus A0A1D5PFJ6 R-GGA-3371503 https://reactome.org/PathwayBrowser/#/R-GGA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Gallus gallus A0A1D5PFJ6 R-GGA-3371518 https://reactome.org/PathwayBrowser/#/R-GGA-3371518 SIRT1 binds to HSF1 IEA Gallus gallus A0A1D5PFJ6 R-GGA-3371554 https://reactome.org/PathwayBrowser/#/R-GGA-3371554 HSF1 acetylation at Lys80 IEA Gallus gallus A0A1D5PFJ6 R-GGA-3371590 https://reactome.org/PathwayBrowser/#/R-GGA-3371590 HSP70 binds to HSP40:nascent protein IEA Gallus gallus A0A1D5PFJ6 R-GGA-450580 https://reactome.org/PathwayBrowser/#/R-GGA-450580 AUF1 (hnRNP D0) is ubiquitinylated IEA Gallus gallus A0A1D5PFJ6 R-GGA-5082356 https://reactome.org/PathwayBrowser/#/R-GGA-5082356 HSF1-mediated gene expression IEA Gallus gallus A0A1D5PFJ6 R-GGA-5082384 https://reactome.org/PathwayBrowser/#/R-GGA-5082384 HSP70:DNAJB1 binds HSF1 IEA Gallus gallus A0A1D5PFJ6 R-GGA-5618085 https://reactome.org/PathwayBrowser/#/R-GGA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Gallus gallus A0A1D5PFJ6 R-GGA-5618098 https://reactome.org/PathwayBrowser/#/R-GGA-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Gallus gallus A0A1D5PFJ6 R-GGA-5618105 https://reactome.org/PathwayBrowser/#/R-GGA-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Gallus gallus A0A1D5PFJ6 R-GGA-5618107 https://reactome.org/PathwayBrowser/#/R-GGA-5618107 ATP binding to HSP90 triggers conformation change IEA Gallus gallus A0A1D5PFJ6 R-GGA-5618110 https://reactome.org/PathwayBrowser/#/R-GGA-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Gallus gallus A0A1D5PFJ6 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PFJ6 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PFJ6 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5PFJ6 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PFJ6 R-GGA-8932221 https://reactome.org/PathwayBrowser/#/R-GGA-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Gallus gallus A0A1D5PFJ6 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5PFJ6 R-GGA-9835411 https://reactome.org/PathwayBrowser/#/R-GGA-9835411 FA core complex:HSP70s binds PKR IEA Gallus gallus A0A1D5PFK3 R-GGA-5615637 https://reactome.org/PathwayBrowser/#/R-GGA-5615637 POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) IEA Gallus gallus A0A1D5PFK3 R-GGA-5617037 https://reactome.org/PathwayBrowser/#/R-GGA-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Gallus gallus A0A1D5PFK3 R-GGA-8879117 https://reactome.org/PathwayBrowser/#/R-GGA-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 IEA Gallus gallus A0A1D5PFK3 R-GGA-8931648 https://reactome.org/PathwayBrowser/#/R-GGA-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Gallus gallus A0A1D5PFK3 R-GGA-8931653 https://reactome.org/PathwayBrowser/#/R-GGA-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Gallus gallus A0A1D5PFK3 R-GGA-9010872 https://reactome.org/PathwayBrowser/#/R-GGA-9010872 SLIT2 binds Dystroglycan IEA Gallus gallus A0A1D5PFK3 R-GGA-9913329 https://reactome.org/PathwayBrowser/#/R-GGA-9913329 Autoproteolysis of DAG1 to alpha and beta chains IEA Gallus gallus A0A1D5PFK3 R-GGA-9913332 https://reactome.org/PathwayBrowser/#/R-GGA-9913332 DAG1(30-653), DAG1(654-895) and SSPN bind SGC IEA Gallus gallus A0A1D5PFK3 R-GGA-9913336 https://reactome.org/PathwayBrowser/#/R-GGA-9913336 SGC:DAG1:SSPN complex translocates to plasma membrane IEA Gallus gallus A0A1D5PFK3 R-GGA-9913337 https://reactome.org/PathwayBrowser/#/R-GGA-9913337 DAG1(30-653) and DAG1(654-895) translocate to the Golgi IEA Gallus gallus A0A1D5PFK3 R-GGA-9913339 https://reactome.org/PathwayBrowser/#/R-GGA-9913339 Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC IEA Gallus gallus A0A1D5PFK7 R-GGA-421831 https://reactome.org/PathwayBrowser/#/R-GGA-421831 trans-Golgi Network Coat Assembly IEA Gallus gallus A0A1D5PFK7 R-GGA-421835 https://reactome.org/PathwayBrowser/#/R-GGA-421835 trans-Golgi Network Vesicle Scission IEA Gallus gallus A0A1D5PFL2 R-GGA-8954398 https://reactome.org/PathwayBrowser/#/R-GGA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Gallus gallus A0A1D5PFL8 R-GGA-2681667 https://reactome.org/PathwayBrowser/#/R-GGA-2681667 TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 IEA Gallus gallus A0A1D5PFL9 R-GGA-111439 https://reactome.org/PathwayBrowser/#/R-GGA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Gallus gallus A0A1D5PFL9 R-GGA-158441 https://reactome.org/PathwayBrowser/#/R-GGA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PFL9 R-GGA-158447 https://reactome.org/PathwayBrowser/#/R-GGA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Gallus gallus A0A1D5PFL9 R-GGA-158481 https://reactome.org/PathwayBrowser/#/R-GGA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PFL9 R-GGA-158484 https://reactome.org/PathwayBrowser/#/R-GGA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Gallus gallus A0A1D5PFL9 R-GGA-159046 https://reactome.org/PathwayBrowser/#/R-GGA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Gallus gallus A0A1D5PFL9 R-GGA-159050 https://reactome.org/PathwayBrowser/#/R-GGA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Gallus gallus A0A1D5PFL9 R-GGA-170825 https://reactome.org/PathwayBrowser/#/R-GGA-170825 NPC exports GCK1 from nucleus IEA Gallus gallus A0A1D5PFL9 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1D5PFL9 R-GGA-2990880 https://reactome.org/PathwayBrowser/#/R-GGA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Gallus gallus A0A1D5PFL9 R-GGA-2990882 https://reactome.org/PathwayBrowser/#/R-GGA-2990882 CDK1 phosphorylates NUP98 IEA Gallus gallus A0A1D5PFL9 R-GGA-4551649 https://reactome.org/PathwayBrowser/#/R-GGA-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Gallus gallus A0A1D5PFL9 R-GGA-4551679 https://reactome.org/PathwayBrowser/#/R-GGA-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Gallus gallus A0A1D5PFL9 R-GGA-4615872 https://reactome.org/PathwayBrowser/#/R-GGA-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Gallus gallus A0A1D5PFL9 R-GGA-4615987 https://reactome.org/PathwayBrowser/#/R-GGA-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Gallus gallus A0A1D5PFL9 R-GGA-4655355 https://reactome.org/PathwayBrowser/#/R-GGA-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Gallus gallus A0A1D5PFL9 R-GGA-5228523 https://reactome.org/PathwayBrowser/#/R-GGA-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Gallus gallus A0A1D5PFL9 R-GGA-5578744 https://reactome.org/PathwayBrowser/#/R-GGA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Gallus gallus A0A1D5PFL9 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1D5PFL9 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1D5PFL9 R-GGA-77587 https://reactome.org/PathwayBrowser/#/R-GGA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Gallus gallus A0A1D5PFL9 R-GGA-9634169 https://reactome.org/PathwayBrowser/#/R-GGA-9634169 POM121 and NDC1 bind the Nup93 complex IEA Gallus gallus A0A1D5PFM1 R-GGA-9933559 https://reactome.org/PathwayBrowser/#/R-GGA-9933559 The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1 IEA Gallus gallus A0A1D5PFM1 R-GGA-9933575 https://reactome.org/PathwayBrowser/#/R-GGA-9933575 MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome IEA Gallus gallus A0A1D5PFM2 R-GGA-198611 https://reactome.org/PathwayBrowser/#/R-GGA-198611 AKT phosphorylates IKKalpha IEA Gallus gallus A0A1D5PFM2 R-GGA-5607722 https://reactome.org/PathwayBrowser/#/R-GGA-5607722 Active NIK phosphorylates IKKA dimer IEA Gallus gallus A0A1D5PFM2 R-GGA-5607723 https://reactome.org/PathwayBrowser/#/R-GGA-5607723 SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB IEA Gallus gallus A0A1D5PFM2 R-GGA-5607726 https://reactome.org/PathwayBrowser/#/R-GGA-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Gallus gallus A0A1D5PFM2 R-GGA-9750226 https://reactome.org/PathwayBrowser/#/R-GGA-9750226 NLRC5 binds IKBKB and CHUK IEA Gallus gallus A0A1D5PFM2 R-GGA-9750946 https://reactome.org/PathwayBrowser/#/R-GGA-9750946 TRAF2,6 ubiquitinates NLRC5 IEA Gallus gallus A0A1D5PFM8 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5PFM8 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5PFM8 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5PFM8 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5PFM8 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5PFM8 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1D5PFM8 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1D5PFM8 R-GGA-9839105 https://reactome.org/PathwayBrowser/#/R-GGA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1D5PFM8 R-GGA-9839149 https://reactome.org/PathwayBrowser/#/R-GGA-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Gallus gallus A0A1D5PFQ5 R-GGA-9750226 https://reactome.org/PathwayBrowser/#/R-GGA-9750226 NLRC5 binds IKBKB and CHUK IEA Gallus gallus A0A1D5PFQ5 R-GGA-9750942 https://reactome.org/PathwayBrowser/#/R-GGA-9750942 USP14 deubiquitinates NLRC5 IEA Gallus gallus A0A1D5PFQ5 R-GGA-9750946 https://reactome.org/PathwayBrowser/#/R-GGA-9750946 TRAF2,6 ubiquitinates NLRC5 IEA Gallus gallus A0A1D5PFQ6 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus A0A1D5PFQ6 R-GGA-73739 https://reactome.org/PathwayBrowser/#/R-GGA-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter IEA Gallus gallus A0A1D5PFQ6 R-GGA-8943780 https://reactome.org/PathwayBrowser/#/R-GGA-8943780 SALL4 recruits NuRD to PTEN gene IEA Gallus gallus A0A1D5PFQ6 R-GGA-9679787 https://reactome.org/PathwayBrowser/#/R-GGA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Gallus gallus A0A1D5PFR7 R-GGA-5205649 https://reactome.org/PathwayBrowser/#/R-GGA-5205649 p62 links damaged mitochondria to LC3 IEA Gallus gallus A0A1D5PFR7 R-GGA-5205663 https://reactome.org/PathwayBrowser/#/R-GGA-5205663 LC3 binds the autophagosome membrane Atg5-Atg12 complex IEA Gallus gallus A0A1D5PFR7 R-GGA-5678490 https://reactome.org/PathwayBrowser/#/R-GGA-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Gallus gallus A0A1D5PFR7 R-GGA-5681987 https://reactome.org/PathwayBrowser/#/R-GGA-5681987 LC3 is cleaved by ATG4 IEA Gallus gallus A0A1D5PFR7 R-GGA-5682011 https://reactome.org/PathwayBrowser/#/R-GGA-5682011 LC3 binds ATG7 dimer IEA Gallus gallus A0A1D5PFR7 R-GGA-5682377 https://reactome.org/PathwayBrowser/#/R-GGA-5682377 LC3 de-lipidation by ATG4 IEA Gallus gallus A0A1D5PFR7 R-GGA-5682388 https://reactome.org/PathwayBrowser/#/R-GGA-5682388 Autophagosome maturation IEA Gallus gallus A0A1D5PFR7 R-GGA-8959571 https://reactome.org/PathwayBrowser/#/R-GGA-8959571 LC3 binds the autophagosome membrane Atg5-Atg12 complex IEA Gallus gallus A0A1D5PFR7 R-GGA-8959573 https://reactome.org/PathwayBrowser/#/R-GGA-8959573 Phosphorylated FUNDC1 links damaged mitochondria to LC3 IEA Gallus gallus A0A1D5PFS2 R-GGA-165680 https://reactome.org/PathwayBrowser/#/R-GGA-165680 Formation of active mTORC1 complex IEA Gallus gallus A0A1D5PFS2 R-GGA-165692 https://reactome.org/PathwayBrowser/#/R-GGA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Gallus gallus A0A1D5PFS2 R-GGA-165718 https://reactome.org/PathwayBrowser/#/R-GGA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Gallus gallus A0A1D5PFS2 R-GGA-377186 https://reactome.org/PathwayBrowser/#/R-GGA-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Gallus gallus A0A1D5PFS2 R-GGA-380979 https://reactome.org/PathwayBrowser/#/R-GGA-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Gallus gallus A0A1D5PFS2 R-GGA-447074 https://reactome.org/PathwayBrowser/#/R-GGA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Gallus gallus A0A1D5PFS2 R-GGA-5653957 https://reactome.org/PathwayBrowser/#/R-GGA-5653957 Rag dimer formation IEA Gallus gallus A0A1D5PFS2 R-GGA-5653968 https://reactome.org/PathwayBrowser/#/R-GGA-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Gallus gallus A0A1D5PFS2 R-GGA-5653974 https://reactome.org/PathwayBrowser/#/R-GGA-5653974 Ragulator binds Rag dimers IEA Gallus gallus A0A1D5PFS2 R-GGA-5672010 https://reactome.org/PathwayBrowser/#/R-GGA-5672010 Active MTORC1 phosphorylates ULK1 IEA Gallus gallus A0A1D5PFS2 R-GGA-5672017 https://reactome.org/PathwayBrowser/#/R-GGA-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Gallus gallus A0A1D5PFS2 R-GGA-5672817 https://reactome.org/PathwayBrowser/#/R-GGA-5672817 Active MTORC1 binds the ULK1 complex IEA Gallus gallus A0A1D5PFS2 R-GGA-5672824 https://reactome.org/PathwayBrowser/#/R-GGA-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Gallus gallus A0A1D5PFS2 R-GGA-5672828 https://reactome.org/PathwayBrowser/#/R-GGA-5672828 mTORC1 phosphorylates AKT1S1 IEA Gallus gallus A0A1D5PFS2 R-GGA-5673768 https://reactome.org/PathwayBrowser/#/R-GGA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Gallus gallus A0A1D5PFS2 R-GGA-5675790 https://reactome.org/PathwayBrowser/#/R-GGA-5675790 MTORC1 dissociates from ULK complex IEA Gallus gallus A0A1D5PFS2 R-GGA-8938815 https://reactome.org/PathwayBrowser/#/R-GGA-8938815 RNF152 polyubiquitinates RRAGA IEA Gallus gallus A0A1D5PFS2 R-GGA-8938829 https://reactome.org/PathwayBrowser/#/R-GGA-8938829 RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 IEA Gallus gallus A0A1D5PFS2 R-GGA-8944454 https://reactome.org/PathwayBrowser/#/R-GGA-8944454 mTORC1 phosphorylates MAF1 IEA Gallus gallus A0A1D5PFS2 R-GGA-8944457 https://reactome.org/PathwayBrowser/#/R-GGA-8944457 MAF1 translocates to the nucleus IEA Gallus gallus A0A1D5PFS2 R-GGA-8952716 https://reactome.org/PathwayBrowser/#/R-GGA-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Gallus gallus A0A1D5PFS2 R-GGA-8952726 https://reactome.org/PathwayBrowser/#/R-GGA-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Gallus gallus A0A1D5PFS2 R-GGA-9639286 https://reactome.org/PathwayBrowser/#/R-GGA-9639286 RRAGC,D exchanges GTP for GDP IEA Gallus gallus A0A1D5PFS2 R-GGA-9640167 https://reactome.org/PathwayBrowser/#/R-GGA-9640167 RRAGA,B exchanges GDP for GTP IEA Gallus gallus A0A1D5PFS2 R-GGA-9640168 https://reactome.org/PathwayBrowser/#/R-GGA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Gallus gallus A0A1D5PFS2 R-GGA-9640175 https://reactome.org/PathwayBrowser/#/R-GGA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Gallus gallus A0A1D5PFS2 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus A0A1D5PFS2 R-GGA-9645598 https://reactome.org/PathwayBrowser/#/R-GGA-9645598 RRAGC,D hydrolyzes GTP IEA Gallus gallus A0A1D5PFS2 R-GGA-9645608 https://reactome.org/PathwayBrowser/#/R-GGA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Gallus gallus A0A1D5PFS2 R-GGA-9646468 https://reactome.org/PathwayBrowser/#/R-GGA-9646468 mTORC1 binds RHEB:GTP IEA Gallus gallus A0A1D5PFS4 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PFS4 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PFT2 R-GGA-5683385 https://reactome.org/PathwayBrowser/#/R-GGA-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Gallus gallus A0A1D5PFT2 R-GGA-5683735 https://reactome.org/PathwayBrowser/#/R-GGA-5683735 CHEK2 is recruited to DNA DSBs IEA Gallus gallus A0A1D5PFT2 R-GGA-5683801 https://reactome.org/PathwayBrowser/#/R-GGA-5683801 CHEK2 phosphorylates BRCA1 IEA Gallus gallus A0A1D5PFT2 R-GGA-5684052 https://reactome.org/PathwayBrowser/#/R-GGA-5684052 PIAS4 SUMOylates MDC1 IEA Gallus gallus A0A1D5PFT2 R-GGA-5686685 https://reactome.org/PathwayBrowser/#/R-GGA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Gallus gallus A0A1D5PFT2 R-GGA-5691411 https://reactome.org/PathwayBrowser/#/R-GGA-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Gallus gallus A0A1D5PFT2 R-GGA-5691439 https://reactome.org/PathwayBrowser/#/R-GGA-5691439 BRISC complex deubiquitinates NLRP3 IEA Gallus gallus A0A1D5PFT2 R-GGA-5693551 https://reactome.org/PathwayBrowser/#/R-GGA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Gallus gallus A0A1D5PFT2 R-GGA-69891 https://reactome.org/PathwayBrowser/#/R-GGA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Gallus gallus A0A1D5PFT4 R-GGA-9933236 https://reactome.org/PathwayBrowser/#/R-GGA-9933236 SS18-containing ATPase complex binds SMARCC dimer:SMARCDs:BICRAs:BRD9 IEA Gallus gallus A0A1D5PFT4 R-GGA-9933238 https://reactome.org/PathwayBrowser/#/R-GGA-9933238 SS18-containing ATPase complex binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1:DPF1,2,3 IEA Gallus gallus A0A1D5PFT4 R-GGA-9934021 https://reactome.org/PathwayBrowser/#/R-GGA-9934021 Formation of neuronal progenitor BAF (npBAF) IEA Gallus gallus A0A1D5PFT4 R-GGA-9934024 https://reactome.org/PathwayBrowser/#/R-GGA-9934024 SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10 IEA Gallus gallus A0A1D5PFT8 R-GGA-421831 https://reactome.org/PathwayBrowser/#/R-GGA-421831 trans-Golgi Network Coat Assembly IEA Gallus gallus A0A1D5PFT8 R-GGA-421835 https://reactome.org/PathwayBrowser/#/R-GGA-421835 trans-Golgi Network Vesicle Scission IEA Gallus gallus A0A1D5PFT8 R-GGA-8867613 https://reactome.org/PathwayBrowser/#/R-GGA-8867613 PICALM binds R-SNAREs IEA Gallus gallus A0A1D5PFT8 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5PFT8 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5PFT8 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5PFT8 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5PFT8 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5PFT8 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5PFT8 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5PFT8 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5PFT8 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PFT8 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PFT8 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5PFT8 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5PFT8 R-GGA-9696268 https://reactome.org/PathwayBrowser/#/R-GGA-9696268 RND3 binds effectors IEA Gallus gallus A0A1D5PFU2 R-GGA-114256 https://reactome.org/PathwayBrowser/#/R-GGA-114256 CYCS:APAF1 binds procaspase-9 IEA Gallus gallus A0A1D5PFU2 R-GGA-6805426 https://reactome.org/PathwayBrowser/#/R-GGA-6805426 CARD8 binds CASP9(1-416) IEA Gallus gallus A0A1D5PFU2 R-GGA-844438 https://reactome.org/PathwayBrowser/#/R-GGA-844438 NLRP1 oligomerizes IEA Gallus gallus A0A1D5PFU2 R-GGA-844447 https://reactome.org/PathwayBrowser/#/R-GGA-844447 NLRP1 senses MDP IEA Gallus gallus A0A1D5PFU2 R-GGA-879201 https://reactome.org/PathwayBrowser/#/R-GGA-879201 Bcl-2 and Bcl-XL bind NLRP1 IEA Gallus gallus A0A1D5PFU2 R-GGA-879222 https://reactome.org/PathwayBrowser/#/R-GGA-879222 MDP:NLRP1 binds ATP IEA Gallus gallus A0A1D5PFU3 R-GGA-199206 https://reactome.org/PathwayBrowser/#/R-GGA-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol IEA Gallus gallus A0A1D5PFU3 R-GGA-199219 https://reactome.org/PathwayBrowser/#/R-GGA-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Gallus gallus A0A1D5PFU3 R-GGA-429581 https://reactome.org/PathwayBrowser/#/R-GGA-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Gallus gallus A0A1D5PFV1 R-GGA-193641 https://reactome.org/PathwayBrowser/#/R-GGA-193641 IKK-beta is recruited IEA Gallus gallus A0A1D5PFV1 R-GGA-193703 https://reactome.org/PathwayBrowser/#/R-GGA-193703 IKKbeta is activated IEA Gallus gallus A0A1D5PFV1 R-GGA-193705 https://reactome.org/PathwayBrowser/#/R-GGA-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate IEA Gallus gallus A0A1D5PFV1 R-GGA-209087 https://reactome.org/PathwayBrowser/#/R-GGA-209087 IKBA is phosphorylated by Phospho IKKB kinase IEA Gallus gallus A0A1D5PFV1 R-GGA-9750226 https://reactome.org/PathwayBrowser/#/R-GGA-9750226 NLRC5 binds IKBKB and CHUK IEA Gallus gallus A0A1D5PFV1 R-GGA-9750946 https://reactome.org/PathwayBrowser/#/R-GGA-9750946 TRAF2,6 ubiquitinates NLRC5 IEA Gallus gallus A0A1D5PFW6 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus A0A1D5PFW6 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus A0A1D5PFW6 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus A0A1D5PFW6 R-GGA-5694410 https://reactome.org/PathwayBrowser/#/R-GGA-5694410 TMED2:TMED10 tetramer binds GPI anchored proteins IEA Gallus gallus A0A1D5PFW6 R-GGA-5694417 https://reactome.org/PathwayBrowser/#/R-GGA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Gallus gallus A0A1D5PFW6 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus A0A1D5PFW6 R-GGA-5694446 https://reactome.org/PathwayBrowser/#/R-GGA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Gallus gallus A0A1D5PFW6 R-GGA-5694522 https://reactome.org/PathwayBrowser/#/R-GGA-5694522 Inner coat assembly and cargo binding IEA Gallus gallus A0A1D5PFW6 R-GGA-5694527 https://reactome.org/PathwayBrowser/#/R-GGA-5694527 Loss of SAR1B GTPase IEA Gallus gallus A0A1D5PFW6 R-GGA-6798747 https://reactome.org/PathwayBrowser/#/R-GGA-6798747 Exocytosis of tertiary granule membrane proteins IEA Gallus gallus A0A1D5PFW6 R-GGA-6799350 https://reactome.org/PathwayBrowser/#/R-GGA-6799350 Exocytosis of specific granule membrane proteins IEA Gallus gallus A0A1D5PFW6 R-GGA-6807877 https://reactome.org/PathwayBrowser/#/R-GGA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Gallus gallus A0A1D5PFW6 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1D5PFW6 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5PFW6 R-GGA-6809011 https://reactome.org/PathwayBrowser/#/R-GGA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Gallus gallus A0A1D5PFX7 R-GGA-388824 https://reactome.org/PathwayBrowser/#/R-GGA-388824 PTPRF, PTPRS, PTPRD bind Liprins IEA Gallus gallus A0A1D5PFX7 R-GGA-6797803 https://reactome.org/PathwayBrowser/#/R-GGA-6797803 PTPRD binds SLITRK1-6 IEA Gallus gallus A0A1D5PFX7 R-GGA-6797810 https://reactome.org/PathwayBrowser/#/R-GGA-6797810 PTPRD binds IL1RAPL1 IEA Gallus gallus A0A1D5PFX7 R-GGA-6800380 https://reactome.org/PathwayBrowser/#/R-GGA-6800380 PTPRD binds IL1RAP-1 IEA Gallus gallus A0A1D5PFY7 R-GGA-888548 https://reactome.org/PathwayBrowser/#/R-GGA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Gallus gallus A0A1D5PFZ5 R-GGA-5693055 https://reactome.org/PathwayBrowser/#/R-GGA-5693055 TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes IEA Gallus gallus A0A1D5PFZ5 R-GGA-5693108 https://reactome.org/PathwayBrowser/#/R-GGA-5693108 TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains IEA Gallus gallus A0A1D5PFZ5 R-GGA-937337 https://reactome.org/PathwayBrowser/#/R-GGA-937337 TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination IEA Gallus gallus A0A1D5PG06 R-GGA-5173005 https://reactome.org/PathwayBrowser/#/R-GGA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Gallus gallus A0A1D5PG06 R-GGA-5173192 https://reactome.org/PathwayBrowser/#/R-GGA-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Gallus gallus A0A1D5PG10 R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus A0A1D5PG10 R-GGA-9621179 https://reactome.org/PathwayBrowser/#/R-GGA-9621179 Cinaciguat binds sGC:NO IEA Gallus gallus A0A1D5PG13 R-GGA-9609921 https://reactome.org/PathwayBrowser/#/R-GGA-9609921 SGTA binds Tail-anchored protein IEA Gallus gallus A0A1D5PG34 R-GGA-1358791 https://reactome.org/PathwayBrowser/#/R-GGA-1358791 Phosphorylation of USP8 by P-AKT IEA Gallus gallus A0A1D5PG34 R-GGA-1358795 https://reactome.org/PathwayBrowser/#/R-GGA-1358795 Deubiquitination of RNF41 by P-USP8 IEA Gallus gallus A0A1D5PG34 R-GGA-1358797 https://reactome.org/PathwayBrowser/#/R-GGA-1358797 Ubiquitinated RNF41 binds P-USP8 IEA Gallus gallus A0A1D5PG34 R-GGA-4641236 https://reactome.org/PathwayBrowser/#/R-GGA-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Gallus gallus A0A1D5PG34 R-GGA-5690196 https://reactome.org/PathwayBrowser/#/R-GGA-5690196 USP8 deubiquitinates RNF128 IEA Gallus gallus A0A1D5PG34 R-GGA-6782628 https://reactome.org/PathwayBrowser/#/R-GGA-6782628 USP8 deubiquitinates STAM2:HGS IEA Gallus gallus A0A1D5PG34 R-GGA-8875443 https://reactome.org/PathwayBrowser/#/R-GGA-8875443 USP8 deubiquitinates LRIG1 IEA Gallus gallus A0A1D5PG44 R-GGA-111439 https://reactome.org/PathwayBrowser/#/R-GGA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Gallus gallus A0A1D5PG44 R-GGA-158441 https://reactome.org/PathwayBrowser/#/R-GGA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PG44 R-GGA-158447 https://reactome.org/PathwayBrowser/#/R-GGA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Gallus gallus A0A1D5PG44 R-GGA-158481 https://reactome.org/PathwayBrowser/#/R-GGA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PG44 R-GGA-158484 https://reactome.org/PathwayBrowser/#/R-GGA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Gallus gallus A0A1D5PG44 R-GGA-159046 https://reactome.org/PathwayBrowser/#/R-GGA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Gallus gallus A0A1D5PG44 R-GGA-159050 https://reactome.org/PathwayBrowser/#/R-GGA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Gallus gallus A0A1D5PG44 R-GGA-170825 https://reactome.org/PathwayBrowser/#/R-GGA-170825 NPC exports GCK1 from nucleus IEA Gallus gallus A0A1D5PG44 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1D5PG44 R-GGA-2990880 https://reactome.org/PathwayBrowser/#/R-GGA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Gallus gallus A0A1D5PG44 R-GGA-2990882 https://reactome.org/PathwayBrowser/#/R-GGA-2990882 CDK1 phosphorylates NUP98 IEA Gallus gallus A0A1D5PG44 R-GGA-4551649 https://reactome.org/PathwayBrowser/#/R-GGA-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Gallus gallus A0A1D5PG44 R-GGA-4551679 https://reactome.org/PathwayBrowser/#/R-GGA-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Gallus gallus A0A1D5PG44 R-GGA-4615872 https://reactome.org/PathwayBrowser/#/R-GGA-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Gallus gallus A0A1D5PG44 R-GGA-4615987 https://reactome.org/PathwayBrowser/#/R-GGA-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Gallus gallus A0A1D5PG44 R-GGA-4655355 https://reactome.org/PathwayBrowser/#/R-GGA-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Gallus gallus A0A1D5PG44 R-GGA-5228523 https://reactome.org/PathwayBrowser/#/R-GGA-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Gallus gallus A0A1D5PG44 R-GGA-5578744 https://reactome.org/PathwayBrowser/#/R-GGA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Gallus gallus A0A1D5PG44 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1D5PG44 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1D5PG44 R-GGA-77587 https://reactome.org/PathwayBrowser/#/R-GGA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Gallus gallus A0A1D5PG44 R-GGA-9634169 https://reactome.org/PathwayBrowser/#/R-GGA-9634169 POM121 and NDC1 bind the Nup93 complex IEA Gallus gallus A0A1D5PG47 R-GGA-2130706 https://reactome.org/PathwayBrowser/#/R-GGA-2130706 MHC class II antigen processing IEA Gallus gallus A0A1D5PG47 R-GGA-5684864 https://reactome.org/PathwayBrowser/#/R-GGA-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Gallus gallus A0A1D5PG47 R-GGA-5685902 https://reactome.org/PathwayBrowser/#/R-GGA-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Gallus gallus A0A1D5PG47 R-GGA-6798745 https://reactome.org/PathwayBrowser/#/R-GGA-6798745 Exocytosis of tertiary granule lumen proteins IEA Gallus gallus A0A1D5PG47 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PG47 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PG53 R-GGA-70349 https://reactome.org/PathwayBrowser/#/R-GGA-70349 DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate IEA Gallus gallus A0A1D5PG74 R-GGA-6805546 https://reactome.org/PathwayBrowser/#/R-GGA-6805546 Keratin type I binds keratin type II IEA Gallus gallus A0A1D5PG74 R-GGA-6805573 https://reactome.org/PathwayBrowser/#/R-GGA-6805573 Keratin type I/type II heterodimers form tetramers IEA Gallus gallus A0A1D5PG74 R-GGA-6806610 https://reactome.org/PathwayBrowser/#/R-GGA-6806610 Keratin filament formation IEA Gallus gallus A0A1D5PG74 R-GGA-6806613 https://reactome.org/PathwayBrowser/#/R-GGA-6806613 Keratin tetramers bind to form unit length filaments IEA Gallus gallus A0A1D5PG74 R-GGA-6806629 https://reactome.org/PathwayBrowser/#/R-GGA-6806629 Formation of tonofilament bundles IEA Gallus gallus A0A1D5PG74 R-GGA-6809393 https://reactome.org/PathwayBrowser/#/R-GGA-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Gallus gallus A0A1D5PG74 R-GGA-6810357 https://reactome.org/PathwayBrowser/#/R-GGA-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Gallus gallus A0A1D5PG75 R-GGA-266046 https://reactome.org/PathwayBrowser/#/R-GGA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Gallus gallus A0A1D5PG75 R-GGA-5433072 https://reactome.org/PathwayBrowser/#/R-GGA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Gallus gallus A0A1D5PG75 R-GGA-8943279 https://reactome.org/PathwayBrowser/#/R-GGA-8943279 GGT dimers hydrolyse GSH IEA Gallus gallus A0A1D5PG75 R-GGA-9753634 https://reactome.org/PathwayBrowser/#/R-GGA-9753634 GGT dimers hydrolyse APAP-SG IEA Gallus gallus A0A1D5PG76 R-GGA-5675656 https://reactome.org/PathwayBrowser/#/R-GGA-5675656 EDA:EDAR binds EDARADD IEA Gallus gallus A0A1D5PGA0 R-GGA-191763 https://reactome.org/PathwayBrowser/#/R-GGA-191763 snRNP:Snurportin complex formation IEA Gallus gallus A0A1D5PGA0 R-GGA-191784 https://reactome.org/PathwayBrowser/#/R-GGA-191784 snRNA Cap hypermethylation IEA Gallus gallus A0A1D5PGA0 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1D5PGA0 R-GGA-75079 https://reactome.org/PathwayBrowser/#/R-GGA-75079 Formation of AT-AC C complex IEA Gallus gallus A0A1D5PGA0 R-GGA-75081 https://reactome.org/PathwayBrowser/#/R-GGA-75081 Formation of AT-AC B Complex IEA Gallus gallus A0A1D5PGA0 R-GGA-75082 https://reactome.org/PathwayBrowser/#/R-GGA-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Gallus gallus A0A1D5PGA0 R-GGA-75083 https://reactome.org/PathwayBrowser/#/R-GGA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Gallus gallus A0A1D5PGA0 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5PGB0 R-GGA-8858346 https://reactome.org/PathwayBrowser/#/R-GGA-8858346 AMHR2 binds AMH IEA Gallus gallus A0A1D5PGB2 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus A0A1D5PGB2 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus A0A1D5PGB2 R-GGA-173626 https://reactome.org/PathwayBrowser/#/R-GGA-173626 Activation of C1r IEA Gallus gallus A0A1D5PGB2 R-GGA-173631 https://reactome.org/PathwayBrowser/#/R-GGA-173631 Activation of C1s IEA Gallus gallus A0A1D5PGB2 R-GGA-8852266 https://reactome.org/PathwayBrowser/#/R-GGA-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Gallus gallus A0A1D5PGB2 R-GGA-8852481 https://reactome.org/PathwayBrowser/#/R-GGA-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Gallus gallus A0A1D5PGB2 R-GGA-9021306 https://reactome.org/PathwayBrowser/#/R-GGA-9021306 C1-Inh binds and inactivates C1r, C1s IEA Gallus gallus A0A1D5PGB5 R-GGA-1678842 https://reactome.org/PathwayBrowser/#/R-GGA-1678842 Competitive inhibition of translation initiation by ISGylated 4EHP IEA Gallus gallus A0A1D5PGC3 R-GGA-1236943 https://reactome.org/PathwayBrowser/#/R-GGA-1236943 Loading of antigen peptide onto MHC class I molecule IEA Gallus gallus A0A1D5PGC3 R-GGA-1236954 https://reactome.org/PathwayBrowser/#/R-GGA-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Gallus gallus A0A1D5PGC3 R-GGA-1236964 https://reactome.org/PathwayBrowser/#/R-GGA-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Gallus gallus A0A1D5PGC3 R-GGA-1236965 https://reactome.org/PathwayBrowser/#/R-GGA-1236965 Export of peptide loaded MHC class I complex to PM IEA Gallus gallus A0A1D5PGC3 R-GGA-198955 https://reactome.org/PathwayBrowser/#/R-GGA-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Gallus gallus A0A1D5PGC3 R-GGA-199062 https://reactome.org/PathwayBrowser/#/R-GGA-199062 KLRC1:KLRD1 heterodimer interacts with HLA-E IEA Gallus gallus A0A1D5PGC3 R-GGA-210289 https://reactome.org/PathwayBrowser/#/R-GGA-210289 Recruitment of SYK to p-DAP12 IEA Gallus gallus A0A1D5PGC3 R-GGA-2395412 https://reactome.org/PathwayBrowser/#/R-GGA-2395412 Phosphorylation of SYK IEA Gallus gallus A0A1D5PGC3 R-GGA-2396594 https://reactome.org/PathwayBrowser/#/R-GGA-2396594 Phosphorylation of SLP-76 by p-SYK IEA Gallus gallus A0A1D5PGC3 R-GGA-2424480 https://reactome.org/PathwayBrowser/#/R-GGA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PGC3 R-GGA-2424482 https://reactome.org/PathwayBrowser/#/R-GGA-2424482 p85 regulatory unit of PI3K binds p-6Y-SYK IEA Gallus gallus A0A1D5PGC3 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus A0A1D5PGC3 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus A0A1D5PGC3 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus A0A1D5PGC3 R-GGA-5691154 https://reactome.org/PathwayBrowser/#/R-GGA-5691154 HFE binds TFRC dimer IEA Gallus gallus A0A1D5PGC3 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5PGC3 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PGC3 R-GGA-8863973 https://reactome.org/PathwayBrowser/#/R-GGA-8863973 Fusion of ERC and phagosome IEA Gallus gallus A0A1D5PGC3 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus A0A1D5PGC3 R-GGA-8951499 https://reactome.org/PathwayBrowser/#/R-GGA-8951499 Loading of antigenic peptides on to class I MHC IEA Gallus gallus A0A1D5PGC3 R-GGA-983138 https://reactome.org/PathwayBrowser/#/R-GGA-983138 Transport of MHC heterotrimer to ER exit site IEA Gallus gallus A0A1D5PGC3 R-GGA-983145 https://reactome.org/PathwayBrowser/#/R-GGA-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Gallus gallus A0A1D5PGC3 R-GGA-983146 https://reactome.org/PathwayBrowser/#/R-GGA-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Gallus gallus A0A1D5PGC3 R-GGA-983421 https://reactome.org/PathwayBrowser/#/R-GGA-983421 Journey of cargo through Golgi complex IEA Gallus gallus A0A1D5PGC3 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus A0A1D5PGC3 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus A0A1D5PGC3 R-GGA-983425 https://reactome.org/PathwayBrowser/#/R-GGA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Gallus gallus A0A1D5PGC3 R-GGA-983427 https://reactome.org/PathwayBrowser/#/R-GGA-983427 Expression of peptide bound class I MHC on cell surface IEA Gallus gallus A0A1D5PGC8 R-GGA-8867876 https://reactome.org/PathwayBrowser/#/R-GGA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Gallus gallus A0A1D5PGD3 R-GGA-8877813 https://reactome.org/PathwayBrowser/#/R-GGA-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Gallus gallus A0A1D5PGE8 R-GGA-4084980 https://reactome.org/PathwayBrowser/#/R-GGA-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Gallus gallus A0A1D5PGE8 R-GGA-981809 https://reactome.org/PathwayBrowser/#/R-GGA-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Gallus gallus A0A1D5PGF4 R-GGA-373075 https://reactome.org/PathwayBrowser/#/R-GGA-373075 Metabotropic glutamate receptors bind glutamate IEA Gallus gallus A0A1D5PGF4 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5PGF4 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5PGF4 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5PGF8 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus A0A1D5PGF8 R-GGA-8938217 https://reactome.org/PathwayBrowser/#/R-GGA-8938217 RUNX1 binds the SWI/SNF complex IEA Gallus gallus A0A1D5PGF8 R-GGA-9932448 https://reactome.org/PathwayBrowser/#/R-GGA-9932448 SMARCC binds SMARCD IEA Gallus gallus A0A1D5PGF8 R-GGA-9932449 https://reactome.org/PathwayBrowser/#/R-GGA-9932449 SMARCE1 and SMARCB1 bind SMARCC dimer:SMARCDs IEA Gallus gallus A0A1D5PGF8 R-GGA-9932832 https://reactome.org/PathwayBrowser/#/R-GGA-9932832 BRD7 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2 IEA Gallus gallus A0A1D5PGF8 R-GGA-9932843 https://reactome.org/PathwayBrowser/#/R-GGA-9932843 PHF10 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD7 IEA Gallus gallus A0A1D5PGF8 R-GGA-9933236 https://reactome.org/PathwayBrowser/#/R-GGA-9933236 SS18-containing ATPase complex binds SMARCC dimer:SMARCDs:BICRAs:BRD9 IEA Gallus gallus A0A1D5PGF8 R-GGA-9933237 https://reactome.org/PathwayBrowser/#/R-GGA-9933237 PBRM1-containing ATPase complex binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD&:PHF10 IEA Gallus gallus A0A1D5PGF8 R-GGA-9934021 https://reactome.org/PathwayBrowser/#/R-GGA-9934021 Formation of neuronal progenitor BAF (npBAF) IEA Gallus gallus A0A1D5PGF8 R-GGA-9934022 https://reactome.org/PathwayBrowser/#/R-GGA-9934022 DPF2, PHF10 bind SMARCC1:SMARCC2 dimer:SMARD1:ARID1A IEA Gallus gallus A0A1D5PGF8 R-GGA-9934024 https://reactome.org/PathwayBrowser/#/R-GGA-9934024 SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10 IEA Gallus gallus A0A1D5PGF8 R-GGA-9934026 https://reactome.org/PathwayBrowser/#/R-GGA-9934026 SMARCE1 and SMARCB1 bind SMARCC1:SMARCC2 dimer:SMARCD1 IEA Gallus gallus A0A1D5PGF8 R-GGA-9934027 https://reactome.org/PathwayBrowser/#/R-GGA-9934027 SMARCC1 and SMARCC2 bind SMARCD1 IEA Gallus gallus A0A1D5PGF9 R-GGA-5624949 https://reactome.org/PathwayBrowser/#/R-GGA-5624949 Assembly of the anterograde IFT train IEA Gallus gallus A0A1D5PGF9 R-GGA-5625416 https://reactome.org/PathwayBrowser/#/R-GGA-5625416 Anterograde IFT IEA Gallus gallus A0A1D5PGF9 R-GGA-5625426 https://reactome.org/PathwayBrowser/#/R-GGA-5625426 Retrograde IFT IEA Gallus gallus A0A1D5PGG4 R-GGA-177923 https://reactome.org/PathwayBrowser/#/R-GGA-177923 Sustained activation of SRC kinase by SHP2 IEA Gallus gallus A0A1D5PGG4 R-GGA-445699 https://reactome.org/PathwayBrowser/#/R-GGA-445699 ATP Hydrolysis By Myosin IEA Gallus gallus A0A1D5PGG4 R-GGA-445700 https://reactome.org/PathwayBrowser/#/R-GGA-445700 Myosin Binds ATP IEA Gallus gallus A0A1D5PGG4 R-GGA-445704 https://reactome.org/PathwayBrowser/#/R-GGA-445704 Calcium Binds Caldesmon IEA Gallus gallus A0A1D5PGG4 R-GGA-445705 https://reactome.org/PathwayBrowser/#/R-GGA-445705 Release Of ADP From Myosin IEA Gallus gallus A0A1D5PGG4 R-GGA-446322 https://reactome.org/PathwayBrowser/#/R-GGA-446322 PARVA associates with Paxillin IEA Gallus gallus A0A1D5PGG4 R-GGA-5218809 https://reactome.org/PathwayBrowser/#/R-GGA-5218809 PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 IEA Gallus gallus A0A1D5PGG4 R-GGA-5218811 https://reactome.org/PathwayBrowser/#/R-GGA-5218811 DOCK180:ELMO binds CRK IEA Gallus gallus A0A1D5PGG4 R-GGA-5218822 https://reactome.org/PathwayBrowser/#/R-GGA-5218822 CRK binds BCAR1 and or PXN IEA Gallus gallus A0A1D5PGG4 R-GGA-5218838 https://reactome.org/PathwayBrowser/#/R-GGA-5218838 PXN binds p-6Y,S732-PTK2 IEA Gallus gallus A0A1D5PGG4 R-GGA-5218839 https://reactome.org/PathwayBrowser/#/R-GGA-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Gallus gallus A0A1D5PGG4 R-GGA-8848611 https://reactome.org/PathwayBrowser/#/R-GGA-8848611 Phosphorylated PXN recruits the CRK complex IEA Gallus gallus A0A1D5PGG4 R-GGA-8848618 https://reactome.org/PathwayBrowser/#/R-GGA-8848618 Activation of RAC1 by the PXN:CRK complex IEA Gallus gallus A0A1D5PGL0 R-GGA-352052 https://reactome.org/PathwayBrowser/#/R-GGA-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol IEA Gallus gallus A0A1D5PGM5 R-GGA-5687360 https://reactome.org/PathwayBrowser/#/R-GGA-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Gallus gallus A0A1D5PGM5 R-GGA-5693574 https://reactome.org/PathwayBrowser/#/R-GGA-5693574 XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ IEA Gallus gallus A0A1D5PGM8 R-GGA-5682388 https://reactome.org/PathwayBrowser/#/R-GGA-5682388 Autophagosome maturation IEA Gallus gallus A0A1D5PGN5 R-GGA-8981892 https://reactome.org/PathwayBrowser/#/R-GGA-8981892 Active G alpha (z) binds RGS proteins IEA Gallus gallus A0A1D5PGN5 R-GGA-8982012 https://reactome.org/PathwayBrowser/#/R-GGA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Gallus gallus A0A1D5PGN5 R-GGA-8982017 https://reactome.org/PathwayBrowser/#/R-GGA-8982017 Active G alpha (q) binds RGS proteins IEA Gallus gallus A0A1D5PGN5 R-GGA-8982018 https://reactome.org/PathwayBrowser/#/R-GGA-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Gallus gallus A0A1D5PGN5 R-GGA-8982019 https://reactome.org/PathwayBrowser/#/R-GGA-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Gallus gallus A0A1D5PGN5 R-GGA-8982020 https://reactome.org/PathwayBrowser/#/R-GGA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Gallus gallus A0A1D5PGN5 R-GGA-8982021 https://reactome.org/PathwayBrowser/#/R-GGA-8982021 G alpha (z) in G alpha (z):RGS complex is inactivated IEA Gallus gallus A0A1D5PGN5 R-GGA-8982025 https://reactome.org/PathwayBrowser/#/R-GGA-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Gallus gallus A0A1D5PGN5 R-GGA-8982026 https://reactome.org/PathwayBrowser/#/R-GGA-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Gallus gallus A0A1D5PGP0 R-GGA-5683964 https://reactome.org/PathwayBrowser/#/R-GGA-5683964 ATM phosphorylates EYA1-4 IEA Gallus gallus A0A1D5PGP0 R-GGA-5683967 https://reactome.org/PathwayBrowser/#/R-GGA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Gallus gallus A0A1D5PGP6 R-GGA-6791222 https://reactome.org/PathwayBrowser/#/R-GGA-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Gallus gallus A0A1D5PGP6 R-GGA-9933575 https://reactome.org/PathwayBrowser/#/R-GGA-9933575 MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome IEA Gallus gallus A0A1D5PGP6 R-GGA-9934522 https://reactome.org/PathwayBrowser/#/R-GGA-9934522 NEXT:ZC3H18:CBCA:m7GpppN-RNA binds the RNA exosome IEA Gallus gallus A0A1D5PGQ5 R-GGA-5226904 https://reactome.org/PathwayBrowser/#/R-GGA-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it IEA Gallus gallus A0A1D5PGR5 R-GGA-2396399 https://reactome.org/PathwayBrowser/#/R-GGA-2396399 Fibrillins bind BMPs IEA Gallus gallus A0A1D5PGR7 R-GGA-448955 https://reactome.org/PathwayBrowser/#/R-GGA-448955 Phosphorylation of MEF2 proteins by p38 IEA Gallus gallus A0A1D5PGR7 R-GGA-448963 https://reactome.org/PathwayBrowser/#/R-GGA-448963 Interaction of MyoD:E protein with MEF2 IEA Gallus gallus A0A1D5PGR9 R-GGA-914010 https://reactome.org/PathwayBrowser/#/R-GGA-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Gallus gallus A0A1D5PGR9 R-GGA-9846501 https://reactome.org/PathwayBrowser/#/R-GGA-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Gallus gallus A0A1D5PGT2 R-GGA-5684864 https://reactome.org/PathwayBrowser/#/R-GGA-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Gallus gallus A0A1D5PGT2 R-GGA-5685902 https://reactome.org/PathwayBrowser/#/R-GGA-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Gallus gallus A0A1D5PGV4 R-GGA-9907912 https://reactome.org/PathwayBrowser/#/R-GGA-9907912 Formation of the outer ring of the 20S core particle IEA Gallus gallus A0A1D5PGV4 R-GGA-9908034 https://reactome.org/PathwayBrowser/#/R-GGA-9908034 PSMG3:PSMG4 dimer binds PSMA5 IEA Gallus gallus A0A1D5PGV4 R-GGA-9908041 https://reactome.org/PathwayBrowser/#/R-GGA-9908041 PSMG3 binds PSMG4 IEA Gallus gallus A0A1D5PGV4 R-GGA-9908052 https://reactome.org/PathwayBrowser/#/R-GGA-9908052 PSMG1:PSMG2 dimer binds the 20S core particle outer ring IEA Gallus gallus A0A1D5PGV4 R-GGA-9908069 https://reactome.org/PathwayBrowser/#/R-GGA-9908069 POMP binds the 20S core particle outer ring IEA Gallus gallus A0A1D5PGW6 R-GGA-70881 https://reactome.org/PathwayBrowser/#/R-GGA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Gallus gallus A0A1D5PGY6 R-GGA-1236943 https://reactome.org/PathwayBrowser/#/R-GGA-1236943 Loading of antigen peptide onto MHC class I molecule IEA Gallus gallus A0A1D5PGY6 R-GGA-1236954 https://reactome.org/PathwayBrowser/#/R-GGA-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Gallus gallus A0A1D5PGY6 R-GGA-1236964 https://reactome.org/PathwayBrowser/#/R-GGA-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Gallus gallus A0A1D5PGY6 R-GGA-1236965 https://reactome.org/PathwayBrowser/#/R-GGA-1236965 Export of peptide loaded MHC class I complex to PM IEA Gallus gallus A0A1D5PGY6 R-GGA-198955 https://reactome.org/PathwayBrowser/#/R-GGA-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Gallus gallus A0A1D5PGY6 R-GGA-199062 https://reactome.org/PathwayBrowser/#/R-GGA-199062 KLRC1:KLRD1 heterodimer interacts with HLA-E IEA Gallus gallus A0A1D5PGY6 R-GGA-210289 https://reactome.org/PathwayBrowser/#/R-GGA-210289 Recruitment of SYK to p-DAP12 IEA Gallus gallus A0A1D5PGY6 R-GGA-2395412 https://reactome.org/PathwayBrowser/#/R-GGA-2395412 Phosphorylation of SYK IEA Gallus gallus A0A1D5PGY6 R-GGA-2396594 https://reactome.org/PathwayBrowser/#/R-GGA-2396594 Phosphorylation of SLP-76 by p-SYK IEA Gallus gallus A0A1D5PGY6 R-GGA-2424480 https://reactome.org/PathwayBrowser/#/R-GGA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PGY6 R-GGA-2424482 https://reactome.org/PathwayBrowser/#/R-GGA-2424482 p85 regulatory unit of PI3K binds p-6Y-SYK IEA Gallus gallus A0A1D5PGY6 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus A0A1D5PGY6 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus A0A1D5PGY6 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus A0A1D5PGY6 R-GGA-5691154 https://reactome.org/PathwayBrowser/#/R-GGA-5691154 HFE binds TFRC dimer IEA Gallus gallus A0A1D5PGY6 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5PGY6 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PGY6 R-GGA-8863973 https://reactome.org/PathwayBrowser/#/R-GGA-8863973 Fusion of ERC and phagosome IEA Gallus gallus A0A1D5PGY6 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus A0A1D5PGY6 R-GGA-8951499 https://reactome.org/PathwayBrowser/#/R-GGA-8951499 Loading of antigenic peptides on to class I MHC IEA Gallus gallus A0A1D5PGY6 R-GGA-983138 https://reactome.org/PathwayBrowser/#/R-GGA-983138 Transport of MHC heterotrimer to ER exit site IEA Gallus gallus A0A1D5PGY6 R-GGA-983145 https://reactome.org/PathwayBrowser/#/R-GGA-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Gallus gallus A0A1D5PGY6 R-GGA-983146 https://reactome.org/PathwayBrowser/#/R-GGA-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Gallus gallus A0A1D5PGY6 R-GGA-983421 https://reactome.org/PathwayBrowser/#/R-GGA-983421 Journey of cargo through Golgi complex IEA Gallus gallus A0A1D5PGY6 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus A0A1D5PGY6 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus A0A1D5PGY6 R-GGA-983425 https://reactome.org/PathwayBrowser/#/R-GGA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Gallus gallus A0A1D5PGY6 R-GGA-983427 https://reactome.org/PathwayBrowser/#/R-GGA-983427 Expression of peptide bound class I MHC on cell surface IEA Gallus gallus A0A1D5PH00 R-GGA-375770 https://reactome.org/PathwayBrowser/#/R-GGA-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids IEA Gallus gallus A0A1D5PH14 R-GGA-5624949 https://reactome.org/PathwayBrowser/#/R-GGA-5624949 Assembly of the anterograde IFT train IEA Gallus gallus A0A1D5PH14 R-GGA-5625416 https://reactome.org/PathwayBrowser/#/R-GGA-5625416 Anterograde IFT IEA Gallus gallus A0A1D5PH14 R-GGA-5625426 https://reactome.org/PathwayBrowser/#/R-GGA-5625426 Retrograde IFT IEA Gallus gallus A0A1D5PH30 R-GGA-376419 https://reactome.org/PathwayBrowser/#/R-GGA-376419 Formation of NR-MED1 Coactivator Complex IEA Gallus gallus A0A1D5PH30 R-GGA-382096 https://reactome.org/PathwayBrowser/#/R-GGA-382096 Formation of NR-NCOR Corepressor Complex IEA Gallus gallus A0A1D5PH36 R-GGA-1678842 https://reactome.org/PathwayBrowser/#/R-GGA-1678842 Competitive inhibition of translation initiation by ISGylated 4EHP IEA Gallus gallus A0A1D5PH36 R-GGA-5653756 https://reactome.org/PathwayBrowser/#/R-GGA-5653756 TRIM25 binds monoUb:164-PCNA IEA Gallus gallus A0A1D5PH36 R-GGA-8852127 https://reactome.org/PathwayBrowser/#/R-GGA-8852127 UBA6 conjugates ubiquitin to cytosolic E2 enzymes IEA Gallus gallus A0A1D5PH36 R-GGA-8852129 https://reactome.org/PathwayBrowser/#/R-GGA-8852129 UBA1 conjugates ubiquitin to cytosolic E2 enzymes IEA Gallus gallus A0A1D5PH36 R-GGA-8852130 https://reactome.org/PathwayBrowser/#/R-GGA-8852130 UBA1 conjugates ubiquitin to nuclear E2 enzymes IEA Gallus gallus A0A1D5PH36 R-GGA-8938770 https://reactome.org/PathwayBrowser/#/R-GGA-8938770 RNF144A binds PRKDC and Ubiquitin:UBE2L3 IEA Gallus gallus A0A1D5PH36 R-GGA-8938773 https://reactome.org/PathwayBrowser/#/R-GGA-8938773 RNF144A polyubiquitinates PRKDC IEA Gallus gallus A0A1D5PH36 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PH36 R-GGA-983152 https://reactome.org/PathwayBrowser/#/R-GGA-983152 Transfer of ubiquitin from E1 to E2 IEA Gallus gallus A0A1D5PH36 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PH36 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PH38 R-GGA-1632857 https://reactome.org/PathwayBrowser/#/R-GGA-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Gallus gallus A0A1D5PH38 R-GGA-5665868 https://reactome.org/PathwayBrowser/#/R-GGA-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Gallus gallus A0A1D5PH38 R-GGA-5672008 https://reactome.org/PathwayBrowser/#/R-GGA-5672008 Thr-180 of ULK1 is phosphorylated IEA Gallus gallus A0A1D5PH38 R-GGA-5672010 https://reactome.org/PathwayBrowser/#/R-GGA-5672010 Active MTORC1 phosphorylates ULK1 IEA Gallus gallus A0A1D5PH38 R-GGA-5672011 https://reactome.org/PathwayBrowser/#/R-GGA-5672011 p-AMPK:AMP binds the ULK complex IEA Gallus gallus A0A1D5PH38 R-GGA-5672817 https://reactome.org/PathwayBrowser/#/R-GGA-5672817 Active MTORC1 binds the ULK1 complex IEA Gallus gallus A0A1D5PH38 R-GGA-5673768 https://reactome.org/PathwayBrowser/#/R-GGA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Gallus gallus A0A1D5PH38 R-GGA-5675790 https://reactome.org/PathwayBrowser/#/R-GGA-5675790 MTORC1 dissociates from ULK complex IEA Gallus gallus A0A1D5PH38 R-GGA-5675868 https://reactome.org/PathwayBrowser/#/R-GGA-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Gallus gallus A0A1D5PH38 R-GGA-5679205 https://reactome.org/PathwayBrowser/#/R-GGA-5679205 ULK1 phosphorylates Beclin-1 IEA Gallus gallus A0A1D5PH38 R-GGA-5679239 https://reactome.org/PathwayBrowser/#/R-GGA-5679239 ULK complex translocates to the ER IEA Gallus gallus A0A1D5PH38 R-GGA-5683925 https://reactome.org/PathwayBrowser/#/R-GGA-5683925 ULK1 is dephosphorylated IEA Gallus gallus A0A1D5PH38 R-GGA-8854759 https://reactome.org/PathwayBrowser/#/R-GGA-8854759 TBC1D14 binds RAB11 and ULK1 IEA Gallus gallus A0A1D5PH38 R-GGA-8876446 https://reactome.org/PathwayBrowser/#/R-GGA-8876446 p-ULK1 phosphorylates DENND3 IEA Gallus gallus A0A1D5PH38 R-GGA-8948136 https://reactome.org/PathwayBrowser/#/R-GGA-8948136 ULK1 Translocates to the mitochondria IEA Gallus gallus A0A1D5PH38 R-GGA-8948146 https://reactome.org/PathwayBrowser/#/R-GGA-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 IEA Gallus gallus A0A1D5PH38 R-GGA-9819106 https://reactome.org/PathwayBrowser/#/R-GGA-9819106 ULK1 phosphorylates RIPK1 at S357 IEA Gallus gallus A0A1D5PH43 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus A0A1D5PH43 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus A0A1D5PH43 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus A0A1D5PH43 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus A0A1D5PH43 R-GGA-5694423 https://reactome.org/PathwayBrowser/#/R-GGA-5694423 NSF and SNAPs bind cis-SNARE complex IEA Gallus gallus A0A1D5PH43 R-GGA-5694425 https://reactome.org/PathwayBrowser/#/R-GGA-5694425 NSF ATPase activity dissociates cis-SNARE IEA Gallus gallus A0A1D5PH43 R-GGA-5694446 https://reactome.org/PathwayBrowser/#/R-GGA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Gallus gallus A0A1D5PH43 R-GGA-6807877 https://reactome.org/PathwayBrowser/#/R-GGA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Gallus gallus A0A1D5PH43 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1D5PH43 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5PH43 R-GGA-6809011 https://reactome.org/PathwayBrowser/#/R-GGA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Gallus gallus A0A1D5PH43 R-GGA-6809014 https://reactome.org/PathwayBrowser/#/R-GGA-6809014 cis-Golgi cis-SNARE binds NSF and SNAPs IEA Gallus gallus A0A1D5PH43 R-GGA-6809015 https://reactome.org/PathwayBrowser/#/R-GGA-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Gallus gallus A0A1D5PH43 R-GGA-8847637 https://reactome.org/PathwayBrowser/#/R-GGA-8847637 NSF and SNAPs bind the cis-SNARE at the Golgi IEA Gallus gallus A0A1D5PH43 R-GGA-8847638 https://reactome.org/PathwayBrowser/#/R-GGA-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Gallus gallus A0A1D5PH43 R-GGA-9013004 https://reactome.org/PathwayBrowser/#/R-GGA-9013004 RHOA binds effectors at the ER membrane IEA Gallus gallus A0A1D5PH43 R-GGA-9014467 https://reactome.org/PathwayBrowser/#/R-GGA-9014467 RHOG binds effectors at the ER membrane IEA Gallus gallus A0A1D5PH43 R-GGA-9691174 https://reactome.org/PathwayBrowser/#/R-GGA-9691174 RAC1 binds effectors at the ER membrane IEA Gallus gallus A0A1D5PH43 R-GGA-9692809 https://reactome.org/PathwayBrowser/#/R-GGA-9692809 CDC42 binds effectors at the ER membrane IEA Gallus gallus A0A1D5PH47 R-GGA-3769397 https://reactome.org/PathwayBrowser/#/R-GGA-3769397 SOST binds LRP5/6 IEA Gallus gallus A0A1D5PH50 R-GGA-1678842 https://reactome.org/PathwayBrowser/#/R-GGA-1678842 Competitive inhibition of translation initiation by ISGylated 4EHP IEA Gallus gallus A0A1D5PH68 R-GGA-549241 https://reactome.org/PathwayBrowser/#/R-GGA-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Gallus gallus A0A1D5PH68 R-GGA-549297 https://reactome.org/PathwayBrowser/#/R-GGA-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Gallus gallus A0A1D5PH72 R-GGA-449715 https://reactome.org/PathwayBrowser/#/R-GGA-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Gallus gallus A0A1D5PH80 R-GGA-508473 https://reactome.org/PathwayBrowser/#/R-GGA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Gallus gallus A0A1D5PH80 R-GGA-70885 https://reactome.org/PathwayBrowser/#/R-GGA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Gallus gallus A0A1D5PHB3 R-GGA-451283 https://reactome.org/PathwayBrowser/#/R-GGA-451283 kainate receptor binds glutamate IEA Gallus gallus A0A1D5PHB3 R-GGA-451309 https://reactome.org/PathwayBrowser/#/R-GGA-451309 Edited Kainate Receptor binds glutamate IEA Gallus gallus A0A1D5PHB3 R-GGA-451310 https://reactome.org/PathwayBrowser/#/R-GGA-451310 Activation of Edited Kainate receptors IEA Gallus gallus A0A1D5PHB3 R-GGA-451311 https://reactome.org/PathwayBrowser/#/R-GGA-451311 Activation of Ca-permeable Kainate receptors IEA Gallus gallus A0A1D5PHB6 R-GGA-3134953 https://reactome.org/PathwayBrowser/#/R-GGA-3134953 DHX36 or DHX9 binds MyD88 IEA Gallus gallus A0A1D5PHB6 R-GGA-3134962 https://reactome.org/PathwayBrowser/#/R-GGA-3134962 DHX36 binds DNA IEA Gallus gallus A0A1D5PHB6 R-GGA-9604487 https://reactome.org/PathwayBrowser/#/R-GGA-9604487 p-IRF7:p-IRF7 translocates to the nucleus IEA Gallus gallus A0A1D5PHC4 R-GGA-2990840 https://reactome.org/PathwayBrowser/#/R-GGA-2990840 SENP1,2,5 proteolytically process SUMO1 IEA Gallus gallus A0A1D5PHC4 R-GGA-2990842 https://reactome.org/PathwayBrowser/#/R-GGA-2990842 SENP1,2,5 proteolytically process SUMO2 IEA Gallus gallus A0A1D5PHC4 R-GGA-2993763 https://reactome.org/PathwayBrowser/#/R-GGA-2993763 SENP1,2,5 proteolytically process SUMO3 IEA Gallus gallus A0A1D5PHD6 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus A0A1D5PHE2 R-GGA-1855154 https://reactome.org/PathwayBrowser/#/R-GGA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus A0A1D5PHE2 R-GGA-1855210 https://reactome.org/PathwayBrowser/#/R-GGA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus A0A1D5PHE2 R-GGA-1855211 https://reactome.org/PathwayBrowser/#/R-GGA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus A0A1D5PHE4 R-GGA-8870332 https://reactome.org/PathwayBrowser/#/R-GGA-8870332 PTPN13:PLEKHA1,2 bind PI(3,4)P2 IEA Gallus gallus A0A1D5PHE8 R-GGA-112385 https://reactome.org/PathwayBrowser/#/R-GGA-112385 Addition of nucleotides leads to transcript elongation IEA Gallus gallus A0A1D5PHE8 R-GGA-112392 https://reactome.org/PathwayBrowser/#/R-GGA-112392 Resumption of elongation after recovery from pausing IEA Gallus gallus A0A1D5PHE8 R-GGA-112395 https://reactome.org/PathwayBrowser/#/R-GGA-112395 Abortive termination of elongation after arrest IEA Gallus gallus A0A1D5PHE8 R-GGA-112396 https://reactome.org/PathwayBrowser/#/R-GGA-112396 Separation of elongating transcript from template IEA Gallus gallus A0A1D5PHE8 R-GGA-113411 https://reactome.org/PathwayBrowser/#/R-GGA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Gallus gallus A0A1D5PHE8 R-GGA-113412 https://reactome.org/PathwayBrowser/#/R-GGA-113412 Pol II elongation complex moves on the template as transcript elongates IEA Gallus gallus A0A1D5PHE8 R-GGA-113413 https://reactome.org/PathwayBrowser/#/R-GGA-113413 TFIIS-mediated recovery of elongation from arrest IEA Gallus gallus A0A1D5PHE8 R-GGA-113414 https://reactome.org/PathwayBrowser/#/R-GGA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Gallus gallus A0A1D5PHE8 R-GGA-3322424 https://reactome.org/PathwayBrowser/#/R-GGA-3322424 Beta-catenin recruits CDC73 and LEO1 IEA Gallus gallus A0A1D5PHH8 R-GGA-429961 https://reactome.org/PathwayBrowser/#/R-GGA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Gallus gallus A0A1D5PHL0 R-GGA-1168640 https://reactome.org/PathwayBrowser/#/R-GGA-1168640 Ubiquitinated IkB is degraded IEA Gallus gallus A0A1D5PHL0 R-GGA-1234159 https://reactome.org/PathwayBrowser/#/R-GGA-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Gallus gallus A0A1D5PHL0 R-GGA-1236970 https://reactome.org/PathwayBrowser/#/R-GGA-1236970 Proteasomal clevage of exogenous antigen (26S proteasome catalyst) IEA Gallus gallus A0A1D5PHL0 R-GGA-1504193 https://reactome.org/PathwayBrowser/#/R-GGA-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-174058 https://reactome.org/PathwayBrowser/#/R-GGA-174058 Degradation of multiubiquitinated Cdh1 IEA Gallus gallus A0A1D5PHL0 R-GGA-174105 https://reactome.org/PathwayBrowser/#/R-GGA-174105 Degradation of multiubiquitinated cell cycle proteins IEA Gallus gallus A0A1D5PHL0 R-GGA-174202 https://reactome.org/PathwayBrowser/#/R-GGA-174202 Degradation of multiubiquitinated Securin IEA Gallus gallus A0A1D5PHL0 R-GGA-174255 https://reactome.org/PathwayBrowser/#/R-GGA-174255 Degradation multiubiquitinated Cyclin A IEA Gallus gallus A0A1D5PHL0 R-GGA-187574 https://reactome.org/PathwayBrowser/#/R-GGA-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-188191 https://reactome.org/PathwayBrowser/#/R-GGA-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Gallus gallus A0A1D5PHL0 R-GGA-209061 https://reactome.org/PathwayBrowser/#/R-GGA-209061 Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex IEA Gallus gallus A0A1D5PHL0 R-GGA-2130282 https://reactome.org/PathwayBrowser/#/R-GGA-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-264458 https://reactome.org/PathwayBrowser/#/R-GGA-264458 Proteasome mediated degradation of COP1 IEA Gallus gallus A0A1D5PHL0 R-GGA-353125 https://reactome.org/PathwayBrowser/#/R-GGA-353125 26S proteosome degrades ODC holoenzyme complex IEA Gallus gallus A0A1D5PHL0 R-GGA-3640874 https://reactome.org/PathwayBrowser/#/R-GGA-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-450466 https://reactome.org/PathwayBrowser/#/R-GGA-450466 AUF1:mRNA complex is destroyed IEA Gallus gallus A0A1D5PHL0 R-GGA-4608855 https://reactome.org/PathwayBrowser/#/R-GGA-4608855 PRICKLE1 is degraded by the proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-4641256 https://reactome.org/PathwayBrowser/#/R-GGA-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-5362448 https://reactome.org/PathwayBrowser/#/R-GGA-5362448 Hh C-terminal fragments are degraded by the proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-5607724 https://reactome.org/PathwayBrowser/#/R-GGA-5607724 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex IEA Gallus gallus A0A1D5PHL0 R-GGA-5610754 https://reactome.org/PathwayBrowser/#/R-GGA-5610754 GLI3 is partially degraded by the proteasome to yield the GLI3 repressor IEA Gallus gallus A0A1D5PHL0 R-GGA-5610758 https://reactome.org/PathwayBrowser/#/R-GGA-5610758 GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP IEA Gallus gallus A0A1D5PHL0 R-GGA-5610760 https://reactome.org/PathwayBrowser/#/R-GGA-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Gallus gallus A0A1D5PHL0 R-GGA-5635854 https://reactome.org/PathwayBrowser/#/R-GGA-5635854 GLI2,3 are degraded by the proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-5635868 https://reactome.org/PathwayBrowser/#/R-GGA-5635868 ub-GLI is degraded by the proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-5658430 https://reactome.org/PathwayBrowser/#/R-GGA-5658430 NF1 is degraded by the proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-5665854 https://reactome.org/PathwayBrowser/#/R-GGA-5665854 ADRM1:26S proteaseome binds UCHL5 IEA Gallus gallus A0A1D5PHL0 R-GGA-5665871 https://reactome.org/PathwayBrowser/#/R-GGA-5665871 ADRM1 binds 26S proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-5668481 https://reactome.org/PathwayBrowser/#/R-GGA-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Gallus gallus A0A1D5PHL0 R-GGA-5668520 https://reactome.org/PathwayBrowser/#/R-GGA-5668520 26Sproteasome degrades K48polyUb-NIK IEA Gallus gallus A0A1D5PHL0 R-GGA-5687112 https://reactome.org/PathwayBrowser/#/R-GGA-5687112 MAPK6 is degraded by the 26S proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-5689539 https://reactome.org/PathwayBrowser/#/R-GGA-5689539 ADRM1:26S proteaseome binds USP14 IEA Gallus gallus A0A1D5PHL0 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PHL0 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PHL0 R-GGA-68825 https://reactome.org/PathwayBrowser/#/R-GGA-68825 Ubiquitinated geminin is degraded by the proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-68948 https://reactome.org/PathwayBrowser/#/R-GGA-68948 Ubiquitinated Orc1 is degraded by the proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-69016 https://reactome.org/PathwayBrowser/#/R-GGA-69016 Ubiquitinated Cdc6 is degraded by the proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-69600 https://reactome.org/PathwayBrowser/#/R-GGA-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Gallus gallus A0A1D5PHL0 R-GGA-75825 https://reactome.org/PathwayBrowser/#/R-GGA-75825 Proteasome mediated degradation of Cyclin D1 IEA Gallus gallus A0A1D5PHL0 R-GGA-8850992 https://reactome.org/PathwayBrowser/#/R-GGA-8850992 Proteasome degrades polyubiquitinated PTEN IEA Gallus gallus A0A1D5PHL0 R-GGA-8854044 https://reactome.org/PathwayBrowser/#/R-GGA-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Gallus gallus A0A1D5PHL0 R-GGA-8854071 https://reactome.org/PathwayBrowser/#/R-GGA-8854071 Proteasome-mediated degradation of PolyUb-FBXL7 IEA Gallus gallus A0A1D5PHL0 R-GGA-8866553 https://reactome.org/PathwayBrowser/#/R-GGA-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-8932355 https://reactome.org/PathwayBrowser/#/R-GGA-8932355 26S proteasome degrades Ub-NFE2L2 IEA Gallus gallus A0A1D5PHL0 R-GGA-8939801 https://reactome.org/PathwayBrowser/#/R-GGA-8939801 26S proteasome degrades PolyUb-RUNX2 IEA Gallus gallus A0A1D5PHL0 R-GGA-8952408 https://reactome.org/PathwayBrowser/#/R-GGA-8952408 Polyubiquitinated RUNX3 is degraded by the proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-8956140 https://reactome.org/PathwayBrowser/#/R-GGA-8956140 NEDD8 and UBD bind NUB1 and the 26S proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-8956184 https://reactome.org/PathwayBrowser/#/R-GGA-8956184 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates IEA Gallus gallus A0A1D5PHL0 R-GGA-8957265 https://reactome.org/PathwayBrowser/#/R-GGA-8957265 26S proteasome degrades TP73 polyubiquitinated by ITCH IEA Gallus gallus A0A1D5PHL0 R-GGA-9755303 https://reactome.org/PathwayBrowser/#/R-GGA-9755303 26S proteasome degrades HIFalpha IEA Gallus gallus A0A1D5PHL0 R-GGA-9755306 https://reactome.org/PathwayBrowser/#/R-GGA-9755306 ub UBXN7 is degraded by the 26S proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-9762096 https://reactome.org/PathwayBrowser/#/R-GGA-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Gallus gallus A0A1D5PHL0 R-GGA-983150 https://reactome.org/PathwayBrowser/#/R-GGA-983150 Proteasomal cleavage of substrate IEA Gallus gallus A0A1D5PHL0 R-GGA-9907912 https://reactome.org/PathwayBrowser/#/R-GGA-9907912 Formation of the outer ring of the 20S core particle IEA Gallus gallus A0A1D5PHL0 R-GGA-9907919 https://reactome.org/PathwayBrowser/#/R-GGA-9907919 Formation of the preholoproteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-9907940 https://reactome.org/PathwayBrowser/#/R-GGA-9907940 Formation of the preholothymoproteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-9907941 https://reactome.org/PathwayBrowser/#/R-GGA-9907941 Fromation of the preholoimmunoproteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-9908052 https://reactome.org/PathwayBrowser/#/R-GGA-9908052 PSMG1:PSMG2 dimer binds the 20S core particle outer ring IEA Gallus gallus A0A1D5PHL0 R-GGA-9908069 https://reactome.org/PathwayBrowser/#/R-GGA-9908069 POMP binds the 20S core particle outer ring IEA Gallus gallus A0A1D5PHL0 R-GGA-9908721 https://reactome.org/PathwayBrowser/#/R-GGA-9908721 Formation of the PA28gamma-20S proteasome IEA Gallus gallus A0A1D5PHL0 R-GGA-9912636 https://reactome.org/PathwayBrowser/#/R-GGA-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Gallus gallus A0A1D5PHL0 R-GGA-9934893 https://reactome.org/PathwayBrowser/#/R-GGA-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 IEA Gallus gallus A0A1D5PHL1 R-GGA-8938356 https://reactome.org/PathwayBrowser/#/R-GGA-8938356 RMB14 binds RUNX2 IEA Gallus gallus A0A1D5PHL2 R-GGA-8875871 https://reactome.org/PathwayBrowser/#/R-GGA-8875871 SLC26A11 transports SO4(2-) from extracellular region to cytosol IEA Gallus gallus A0A1D5PHM1 R-GGA-6805811 https://reactome.org/PathwayBrowser/#/R-GGA-6805811 Release of SEPT4 from mitochondria IEA Gallus gallus A0A1D5PHM1 R-GGA-9627369 https://reactome.org/PathwayBrowser/#/R-GGA-9627369 SEPT4 binds XIAP IEA Gallus gallus A0A1D5PHM2 R-GGA-2684901 https://reactome.org/PathwayBrowser/#/R-GGA-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Gallus gallus A0A1D5PHP4 R-GGA-1112666 https://reactome.org/PathwayBrowser/#/R-GGA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Gallus gallus A0A1D5PHP4 R-GGA-114689 https://reactome.org/PathwayBrowser/#/R-GGA-114689 PLC gamma 2-mediated PIP2 hydrolysis IEA Gallus gallus A0A1D5PHP4 R-GGA-1855221 https://reactome.org/PathwayBrowser/#/R-GGA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Gallus gallus A0A1D5PHP4 R-GGA-202407 https://reactome.org/PathwayBrowser/#/R-GGA-202407 PLC-gamma1 hydrolyses PIP2 IEA Gallus gallus A0A1D5PHP4 R-GGA-2029268 https://reactome.org/PathwayBrowser/#/R-GGA-2029268 Phosphorylation and activation of PLCG IEA Gallus gallus A0A1D5PHP4 R-GGA-2029270 https://reactome.org/PathwayBrowser/#/R-GGA-2029270 Recruitment of PLCgamma to membrane IEA Gallus gallus A0A1D5PHP4 R-GGA-2029272 https://reactome.org/PathwayBrowser/#/R-GGA-2029272 Release of PLCG from FCGR IEA Gallus gallus A0A1D5PHP4 R-GGA-2201293 https://reactome.org/PathwayBrowser/#/R-GGA-2201293 Endocytosis of TLR4:LY96:LPS:CD14 IEA Gallus gallus A0A1D5PHP4 R-GGA-2396594 https://reactome.org/PathwayBrowser/#/R-GGA-2396594 Phosphorylation of SLP-76 by p-SYK IEA Gallus gallus A0A1D5PHP4 R-GGA-2396606 https://reactome.org/PathwayBrowser/#/R-GGA-2396606 Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT IEA Gallus gallus A0A1D5PHP4 R-GGA-2424476 https://reactome.org/PathwayBrowser/#/R-GGA-2424476 Activation of RAC1 by VAV2/3 IEA Gallus gallus A0A1D5PHP4 R-GGA-2424481 https://reactome.org/PathwayBrowser/#/R-GGA-2424481 Recruitment of VAV and BTK to p-SLP-76 IEA Gallus gallus A0A1D5PHP4 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus A0A1D5PHP4 R-GGA-2424485 https://reactome.org/PathwayBrowser/#/R-GGA-2424485 Release of p-PLCG1 IEA Gallus gallus A0A1D5PHP4 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus A0A1D5PHP4 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus A0A1D5PHP4 R-GGA-2730840 https://reactome.org/PathwayBrowser/#/R-GGA-2730840 Activation of RAC1 by VAV IEA Gallus gallus A0A1D5PHP4 R-GGA-2730841 https://reactome.org/PathwayBrowser/#/R-GGA-2730841 Phosphorylation and activation of VAV IEA Gallus gallus A0A1D5PHP4 R-GGA-2730847 https://reactome.org/PathwayBrowser/#/R-GGA-2730847 Hydrolysis of PIP2 by PLCG IEA Gallus gallus A0A1D5PHP4 R-GGA-2730856 https://reactome.org/PathwayBrowser/#/R-GGA-2730856 Autophosphorylation of PAK IEA Gallus gallus A0A1D5PHP4 R-GGA-2730858 https://reactome.org/PathwayBrowser/#/R-GGA-2730858 Autophosphorylation of BTK/ITK IEA Gallus gallus A0A1D5PHP4 R-GGA-2730889 https://reactome.org/PathwayBrowser/#/R-GGA-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Gallus gallus A0A1D5PHP4 R-GGA-2730892 https://reactome.org/PathwayBrowser/#/R-GGA-2730892 Recruitment of VAV to p-SLP-76 IEA Gallus gallus A0A1D5PHP4 R-GGA-429497 https://reactome.org/PathwayBrowser/#/R-GGA-429497 SLP-76 stimulates PLC gamma 2 IEA Gallus gallus A0A1D5PHP4 R-GGA-5607735 https://reactome.org/PathwayBrowser/#/R-GGA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Gallus gallus A0A1D5PHP4 R-GGA-5607755 https://reactome.org/PathwayBrowser/#/R-GGA-5607755 p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane IEA Gallus gallus A0A1D5PHP4 R-GGA-9606894 https://reactome.org/PathwayBrowser/#/R-GGA-9606894 p-DAPP1 (p-BAM32) binds PLCG2 IEA Gallus gallus A0A1D5PHP4 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus A0A1D5PHQ4 R-GGA-425483 https://reactome.org/PathwayBrowser/#/R-GGA-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Gallus gallus A0A1D5PHQ9 R-GGA-5696131 https://reactome.org/PathwayBrowser/#/R-GGA-5696131 AOC1 deaminates Hist IEA Gallus gallus A0A1D5PHQ9 R-GGA-6798749 https://reactome.org/PathwayBrowser/#/R-GGA-6798749 Exocytosis of specific granule lumen proteins IEA Gallus gallus A0A1D5PHR1 R-GGA-382575 https://reactome.org/PathwayBrowser/#/R-GGA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Gallus gallus A0A1D5PHR1 R-GGA-382613 https://reactome.org/PathwayBrowser/#/R-GGA-382613 PEX-19 docks ABCD1/D2/D3 to peroximal membrane IEA Gallus gallus A0A1D5PHR1 R-GGA-9603775 https://reactome.org/PathwayBrowser/#/R-GGA-9603775 PEX3:PEX19:class I PMP dissociates IEA Gallus gallus A0A1D5PHR1 R-GGA-9603784 https://reactome.org/PathwayBrowser/#/R-GGA-9603784 PEX19:class I PMP binds PEX3 IEA Gallus gallus A0A1D5PHR1 R-GGA-9603804 https://reactome.org/PathwayBrowser/#/R-GGA-9603804 PEX19 binds class I peroxisomal membrane proteins IEA Gallus gallus A0A1D5PHS1 R-GGA-939763 https://reactome.org/PathwayBrowser/#/R-GGA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Gallus gallus A0A1D5PHS1 R-GGA-947591 https://reactome.org/PathwayBrowser/#/R-GGA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Gallus gallus A0A1D5PHS2 R-GGA-6805546 https://reactome.org/PathwayBrowser/#/R-GGA-6805546 Keratin type I binds keratin type II IEA Gallus gallus A0A1D5PHS2 R-GGA-6805573 https://reactome.org/PathwayBrowser/#/R-GGA-6805573 Keratin type I/type II heterodimers form tetramers IEA Gallus gallus A0A1D5PHS2 R-GGA-6806610 https://reactome.org/PathwayBrowser/#/R-GGA-6806610 Keratin filament formation IEA Gallus gallus A0A1D5PHS2 R-GGA-6806613 https://reactome.org/PathwayBrowser/#/R-GGA-6806613 Keratin tetramers bind to form unit length filaments IEA Gallus gallus A0A1D5PHS2 R-GGA-6806629 https://reactome.org/PathwayBrowser/#/R-GGA-6806629 Formation of tonofilament bundles IEA Gallus gallus A0A1D5PHS2 R-GGA-6809393 https://reactome.org/PathwayBrowser/#/R-GGA-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Gallus gallus A0A1D5PHS2 R-GGA-6810357 https://reactome.org/PathwayBrowser/#/R-GGA-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Gallus gallus A0A1D5PHS9 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5PHS9 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5PHU2 R-GGA-372505 https://reactome.org/PathwayBrowser/#/R-GGA-372505 Acetylcholine synaptic vesicle docking and priming IEA Gallus gallus A0A1D5PHU2 R-GGA-374922 https://reactome.org/PathwayBrowser/#/R-GGA-374922 Noradrenalin synaptic vesicle docking and priming IEA Gallus gallus A0A1D5PHX5 R-GGA-6807877 https://reactome.org/PathwayBrowser/#/R-GGA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Gallus gallus A0A1D5PHX5 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1D5PHX5 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5PHX5 R-GGA-6809011 https://reactome.org/PathwayBrowser/#/R-GGA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Gallus gallus A0A1D5PHX5 R-GGA-6811417 https://reactome.org/PathwayBrowser/#/R-GGA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Gallus gallus A0A1D5PHX5 R-GGA-6811418 https://reactome.org/PathwayBrowser/#/R-GGA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Gallus gallus A0A1D5PHX5 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5PHX5 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5PHZ6 R-GGA-199863 https://reactome.org/PathwayBrowser/#/R-GGA-199863 AKT can phosphorylate NR4A1 (NUR77) IEA Gallus gallus A0A1D5PHZ6 R-GGA-376419 https://reactome.org/PathwayBrowser/#/R-GGA-376419 Formation of NR-MED1 Coactivator Complex IEA Gallus gallus A0A1D5PHZ6 R-GGA-382096 https://reactome.org/PathwayBrowser/#/R-GGA-382096 Formation of NR-NCOR Corepressor Complex IEA Gallus gallus A0A1D5PI02 R-GGA-1614362 https://reactome.org/PathwayBrowser/#/R-GGA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Gallus gallus A0A1D5PI06 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus A0A1D5PI06 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus A0A1D5PI06 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus A0A1D5PI21 R-GGA-72670 https://reactome.org/PathwayBrowser/#/R-GGA-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Gallus gallus A0A1D5PI21 R-GGA-72722 https://reactome.org/PathwayBrowser/#/R-GGA-72722 eIF2 activation IEA Gallus gallus A0A1D5PI23 R-GGA-203797 https://reactome.org/PathwayBrowser/#/R-GGA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Gallus gallus A0A1D5PI39 R-GGA-1168640 https://reactome.org/PathwayBrowser/#/R-GGA-1168640 Ubiquitinated IkB is degraded IEA Gallus gallus A0A1D5PI39 R-GGA-1234159 https://reactome.org/PathwayBrowser/#/R-GGA-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Gallus gallus A0A1D5PI39 R-GGA-1236970 https://reactome.org/PathwayBrowser/#/R-GGA-1236970 Proteasomal clevage of exogenous antigen (26S proteasome catalyst) IEA Gallus gallus A0A1D5PI39 R-GGA-1504193 https://reactome.org/PathwayBrowser/#/R-GGA-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-174058 https://reactome.org/PathwayBrowser/#/R-GGA-174058 Degradation of multiubiquitinated Cdh1 IEA Gallus gallus A0A1D5PI39 R-GGA-174105 https://reactome.org/PathwayBrowser/#/R-GGA-174105 Degradation of multiubiquitinated cell cycle proteins IEA Gallus gallus A0A1D5PI39 R-GGA-174202 https://reactome.org/PathwayBrowser/#/R-GGA-174202 Degradation of multiubiquitinated Securin IEA Gallus gallus A0A1D5PI39 R-GGA-174255 https://reactome.org/PathwayBrowser/#/R-GGA-174255 Degradation multiubiquitinated Cyclin A IEA Gallus gallus A0A1D5PI39 R-GGA-187574 https://reactome.org/PathwayBrowser/#/R-GGA-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-188191 https://reactome.org/PathwayBrowser/#/R-GGA-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Gallus gallus A0A1D5PI39 R-GGA-209061 https://reactome.org/PathwayBrowser/#/R-GGA-209061 Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex IEA Gallus gallus A0A1D5PI39 R-GGA-2130282 https://reactome.org/PathwayBrowser/#/R-GGA-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-264458 https://reactome.org/PathwayBrowser/#/R-GGA-264458 Proteasome mediated degradation of COP1 IEA Gallus gallus A0A1D5PI39 R-GGA-353125 https://reactome.org/PathwayBrowser/#/R-GGA-353125 26S proteosome degrades ODC holoenzyme complex IEA Gallus gallus A0A1D5PI39 R-GGA-3640874 https://reactome.org/PathwayBrowser/#/R-GGA-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-450466 https://reactome.org/PathwayBrowser/#/R-GGA-450466 AUF1:mRNA complex is destroyed IEA Gallus gallus A0A1D5PI39 R-GGA-4608855 https://reactome.org/PathwayBrowser/#/R-GGA-4608855 PRICKLE1 is degraded by the proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-4641256 https://reactome.org/PathwayBrowser/#/R-GGA-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-5362448 https://reactome.org/PathwayBrowser/#/R-GGA-5362448 Hh C-terminal fragments are degraded by the proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-5607724 https://reactome.org/PathwayBrowser/#/R-GGA-5607724 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex IEA Gallus gallus A0A1D5PI39 R-GGA-5610754 https://reactome.org/PathwayBrowser/#/R-GGA-5610754 GLI3 is partially degraded by the proteasome to yield the GLI3 repressor IEA Gallus gallus A0A1D5PI39 R-GGA-5610758 https://reactome.org/PathwayBrowser/#/R-GGA-5610758 GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP IEA Gallus gallus A0A1D5PI39 R-GGA-5610760 https://reactome.org/PathwayBrowser/#/R-GGA-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Gallus gallus A0A1D5PI39 R-GGA-5635854 https://reactome.org/PathwayBrowser/#/R-GGA-5635854 GLI2,3 are degraded by the proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-5635868 https://reactome.org/PathwayBrowser/#/R-GGA-5635868 ub-GLI is degraded by the proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-5658430 https://reactome.org/PathwayBrowser/#/R-GGA-5658430 NF1 is degraded by the proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-5665854 https://reactome.org/PathwayBrowser/#/R-GGA-5665854 ADRM1:26S proteaseome binds UCHL5 IEA Gallus gallus A0A1D5PI39 R-GGA-5665871 https://reactome.org/PathwayBrowser/#/R-GGA-5665871 ADRM1 binds 26S proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-5668481 https://reactome.org/PathwayBrowser/#/R-GGA-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Gallus gallus A0A1D5PI39 R-GGA-5668520 https://reactome.org/PathwayBrowser/#/R-GGA-5668520 26Sproteasome degrades K48polyUb-NIK IEA Gallus gallus A0A1D5PI39 R-GGA-5687112 https://reactome.org/PathwayBrowser/#/R-GGA-5687112 MAPK6 is degraded by the 26S proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-5689539 https://reactome.org/PathwayBrowser/#/R-GGA-5689539 ADRM1:26S proteaseome binds USP14 IEA Gallus gallus A0A1D5PI39 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5PI39 R-GGA-68825 https://reactome.org/PathwayBrowser/#/R-GGA-68825 Ubiquitinated geminin is degraded by the proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-68948 https://reactome.org/PathwayBrowser/#/R-GGA-68948 Ubiquitinated Orc1 is degraded by the proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-69016 https://reactome.org/PathwayBrowser/#/R-GGA-69016 Ubiquitinated Cdc6 is degraded by the proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-69600 https://reactome.org/PathwayBrowser/#/R-GGA-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Gallus gallus A0A1D5PI39 R-GGA-75825 https://reactome.org/PathwayBrowser/#/R-GGA-75825 Proteasome mediated degradation of Cyclin D1 IEA Gallus gallus A0A1D5PI39 R-GGA-8850992 https://reactome.org/PathwayBrowser/#/R-GGA-8850992 Proteasome degrades polyubiquitinated PTEN IEA Gallus gallus A0A1D5PI39 R-GGA-8854044 https://reactome.org/PathwayBrowser/#/R-GGA-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Gallus gallus A0A1D5PI39 R-GGA-8854071 https://reactome.org/PathwayBrowser/#/R-GGA-8854071 Proteasome-mediated degradation of PolyUb-FBXL7 IEA Gallus gallus A0A1D5PI39 R-GGA-8866553 https://reactome.org/PathwayBrowser/#/R-GGA-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-8932355 https://reactome.org/PathwayBrowser/#/R-GGA-8932355 26S proteasome degrades Ub-NFE2L2 IEA Gallus gallus A0A1D5PI39 R-GGA-8939801 https://reactome.org/PathwayBrowser/#/R-GGA-8939801 26S proteasome degrades PolyUb-RUNX2 IEA Gallus gallus A0A1D5PI39 R-GGA-8952408 https://reactome.org/PathwayBrowser/#/R-GGA-8952408 Polyubiquitinated RUNX3 is degraded by the proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-8956140 https://reactome.org/PathwayBrowser/#/R-GGA-8956140 NEDD8 and UBD bind NUB1 and the 26S proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-8956184 https://reactome.org/PathwayBrowser/#/R-GGA-8956184 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates IEA Gallus gallus A0A1D5PI39 R-GGA-8957265 https://reactome.org/PathwayBrowser/#/R-GGA-8957265 26S proteasome degrades TP73 polyubiquitinated by ITCH IEA Gallus gallus A0A1D5PI39 R-GGA-9755303 https://reactome.org/PathwayBrowser/#/R-GGA-9755303 26S proteasome degrades HIFalpha IEA Gallus gallus A0A1D5PI39 R-GGA-9755306 https://reactome.org/PathwayBrowser/#/R-GGA-9755306 ub UBXN7 is degraded by the 26S proteasome IEA Gallus gallus A0A1D5PI39 R-GGA-9762096 https://reactome.org/PathwayBrowser/#/R-GGA-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Gallus gallus A0A1D5PI39 R-GGA-983150 https://reactome.org/PathwayBrowser/#/R-GGA-983150 Proteasomal cleavage of substrate IEA Gallus gallus A0A1D5PI39 R-GGA-9908026 https://reactome.org/PathwayBrowser/#/R-GGA-9908026 Formation of the 19S regulatory particle precursor IEA Gallus gallus A0A1D5PI39 R-GGA-9934893 https://reactome.org/PathwayBrowser/#/R-GGA-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 IEA Gallus gallus A0A1D5PI42 R-GGA-8857577 https://reactome.org/PathwayBrowser/#/R-GGA-8857577 LINC01139 facilitates PTK6 autophosphorylation IEA Gallus gallus A0A1D5PI42 R-GGA-8857583 https://reactome.org/PathwayBrowser/#/R-GGA-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Gallus gallus A0A1D5PI42 R-GGA-9634702 https://reactome.org/PathwayBrowser/#/R-GGA-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Gallus gallus A0A1D5PI43 R-GGA-141200 https://reactome.org/PathwayBrowser/#/R-GGA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Gallus gallus A0A1D5PI43 R-GGA-141202 https://reactome.org/PathwayBrowser/#/R-GGA-141202 MAOB:FAD oxidatively deaminates TYR IEA Gallus gallus A0A1D5PI43 R-GGA-9677929 https://reactome.org/PathwayBrowser/#/R-GGA-9677929 MAOB inhibitors bind MAOB:FAD IEA Gallus gallus A0A1D5PI44 R-GGA-174439 https://reactome.org/PathwayBrowser/#/R-GGA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Gallus gallus A0A1D5PI44 R-GGA-174452 https://reactome.org/PathwayBrowser/#/R-GGA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Gallus gallus A0A1D5PI44 R-GGA-9668902 https://reactome.org/PathwayBrowser/#/R-GGA-9668902 Formation of the CTF18-RFC(7s) complex IEA Gallus gallus A0A1D5PI44 R-GGA-9668904 https://reactome.org/PathwayBrowser/#/R-GGA-9668904 Formation of the CTF18 complex IEA Gallus gallus A0A1D5PI45 R-GGA-8855617 https://reactome.org/PathwayBrowser/#/R-GGA-8855617 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 IEA Gallus gallus A0A1D5PI58 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5PI58 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1D5PI58 R-GGA-8938108 https://reactome.org/PathwayBrowser/#/R-GGA-8938108 SERPINB13 binds cathepsin L IEA Gallus gallus A0A1D5PI58 R-GGA-8938121 https://reactome.org/PathwayBrowser/#/R-GGA-8938121 SERPINB13 binds CTSK IEA Gallus gallus A0A1D5PI60 R-GGA-1296127 https://reactome.org/PathwayBrowser/#/R-GGA-1296127 Activation of voltage gated Potassium channels IEA Gallus gallus A0A1D5PI86 R-GGA-5624949 https://reactome.org/PathwayBrowser/#/R-GGA-5624949 Assembly of the anterograde IFT train IEA Gallus gallus A0A1D5PI86 R-GGA-5625416 https://reactome.org/PathwayBrowser/#/R-GGA-5625416 Anterograde IFT IEA Gallus gallus A0A1D5PI86 R-GGA-5625426 https://reactome.org/PathwayBrowser/#/R-GGA-5625426 Retrograde IFT IEA Gallus gallus A0A1D5PI87 R-GGA-508369 https://reactome.org/PathwayBrowser/#/R-GGA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Gallus gallus A0A1D5PI87 R-GGA-70837 https://reactome.org/PathwayBrowser/#/R-GGA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Gallus gallus A0A1D5PI87 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1D5PI87 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1D5PI98 R-GGA-1296127 https://reactome.org/PathwayBrowser/#/R-GGA-1296127 Activation of voltage gated Potassium channels IEA Gallus gallus A0A1D5PIB1 R-GGA-376419 https://reactome.org/PathwayBrowser/#/R-GGA-376419 Formation of NR-MED1 Coactivator Complex IEA Gallus gallus A0A1D5PIB1 R-GGA-382096 https://reactome.org/PathwayBrowser/#/R-GGA-382096 Formation of NR-NCOR Corepressor Complex IEA Gallus gallus A0A1D5PIB1 R-GGA-4341025 https://reactome.org/PathwayBrowser/#/R-GGA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Gallus gallus A0A1D5PIB1 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus A0A1D5PIB1 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus A0A1D5PIB1 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus A0A1D5PIB1 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus A0A1D5PIC5 R-GGA-2076611 https://reactome.org/PathwayBrowser/#/R-GGA-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Gallus gallus A0A1D5PIC8 R-GGA-507868 https://reactome.org/PathwayBrowser/#/R-GGA-507868 Aquaporins passively transport water into cells IEA Gallus gallus A0A1D5PIC8 R-GGA-507870 https://reactome.org/PathwayBrowser/#/R-GGA-507870 Aquaporins passively transport water out of cells IEA Gallus gallus A0A1D5PIE4 R-GGA-350600 https://reactome.org/PathwayBrowser/#/R-GGA-350600 Antizyme inhibitor binds to OAZ and stablizes ODC complex IEA Gallus gallus A0A1D5PIF0 R-GGA-70994 https://reactome.org/PathwayBrowser/#/R-GGA-70994 SDH complex dehydrogenates succinate IEA Gallus gallus A0A1D5PIG8 R-GGA-6811431 https://reactome.org/PathwayBrowser/#/R-GGA-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Gallus gallus A0A1D5PIG8 R-GGA-6814682 https://reactome.org/PathwayBrowser/#/R-GGA-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Gallus gallus A0A1D5PIG8 R-GGA-6814683 https://reactome.org/PathwayBrowser/#/R-GGA-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN IEA Gallus gallus A0A1D5PIG8 R-GGA-6814684 https://reactome.org/PathwayBrowser/#/R-GGA-6814684 cis-SNARE binds SNAPs and NSF hexamer at the TGN IEA Gallus gallus A0A1D5PIG8 R-GGA-8866277 https://reactome.org/PathwayBrowser/#/R-GGA-8866277 AP-2 directly binds some endocytic cargo IEA Gallus gallus A0A1D5PIG8 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5PIG8 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5PIG8 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5PIG8 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5PIG8 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5PIG8 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5PIG8 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5PIG8 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5PIG8 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PIG8 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PIG8 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5PIG8 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5PIH8 R-GGA-2574840 https://reactome.org/PathwayBrowser/#/R-GGA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Gallus gallus A0A1D5PIH8 R-GGA-2574845 https://reactome.org/PathwayBrowser/#/R-GGA-2574845 AJUBA binds centrosome-associated AURKA IEA Gallus gallus A0A1D5PIH8 R-GGA-3000310 https://reactome.org/PathwayBrowser/#/R-GGA-3000310 AURKA phosphorylates PLK1 IEA Gallus gallus A0A1D5PIH8 R-GGA-3000319 https://reactome.org/PathwayBrowser/#/R-GGA-3000319 BORA binds PLK1 and AURKA IEA Gallus gallus A0A1D5PIH8 R-GGA-380272 https://reactome.org/PathwayBrowser/#/R-GGA-380272 Plk1-mediated phosphorylation of Nlp IEA Gallus gallus A0A1D5PIH8 R-GGA-380283 https://reactome.org/PathwayBrowser/#/R-GGA-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Gallus gallus A0A1D5PIH8 R-GGA-380294 https://reactome.org/PathwayBrowser/#/R-GGA-380294 Loss of C-Nap-1 from centrosomes IEA Gallus gallus A0A1D5PIH8 R-GGA-380311 https://reactome.org/PathwayBrowser/#/R-GGA-380311 Recruitment of Plk1 to centrosomes IEA Gallus gallus A0A1D5PIH8 R-GGA-380455 https://reactome.org/PathwayBrowser/#/R-GGA-380455 Recruitment of CDK11p58 to the centrosomes IEA Gallus gallus A0A1D5PIH8 R-GGA-380508 https://reactome.org/PathwayBrowser/#/R-GGA-380508 Translocation of NuMA to the centrosomes IEA Gallus gallus A0A1D5PIH8 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5PIH8 R-GGA-5626228 https://reactome.org/PathwayBrowser/#/R-GGA-5626228 The distal appendage proteins recruit TTBK2 IEA Gallus gallus A0A1D5PIH8 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1D5PIH8 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1D5PIH8 R-GGA-8853405 https://reactome.org/PathwayBrowser/#/R-GGA-8853405 TPX2 binds AURKA at centrosomes IEA Gallus gallus A0A1D5PIH8 R-GGA-8853419 https://reactome.org/PathwayBrowser/#/R-GGA-8853419 TPX2 promotes AURKA autophosphorylation IEA Gallus gallus A0A1D5PII3 R-GGA-3928578 https://reactome.org/PathwayBrowser/#/R-GGA-3928578 EPH receptors autophosphorylate IEA Gallus gallus A0A1D5PII3 R-GGA-3928591 https://reactome.org/PathwayBrowser/#/R-GGA-3928591 EPH:EFN tetramers oligomerise IEA Gallus gallus A0A1D5PII3 R-GGA-3928597 https://reactome.org/PathwayBrowser/#/R-GGA-3928597 EPH:EFN dimers tetramerise IEA Gallus gallus A0A1D5PII3 R-GGA-3928604 https://reactome.org/PathwayBrowser/#/R-GGA-3928604 SFKs phosphorylate VAV2,3 IEA Gallus gallus A0A1D5PII3 R-GGA-3928607 https://reactome.org/PathwayBrowser/#/R-GGA-3928607 p-EPHs bind VAV2,3 IEA Gallus gallus A0A1D5PII3 R-GGA-3928628 https://reactome.org/PathwayBrowser/#/R-GGA-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5PII3 R-GGA-3928642 https://reactome.org/PathwayBrowser/#/R-GGA-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5PII3 R-GGA-3928646 https://reactome.org/PathwayBrowser/#/R-GGA-3928646 EPHAs bind EFNAs IEA Gallus gallus A0A1D5PII3 R-GGA-3928651 https://reactome.org/PathwayBrowser/#/R-GGA-3928651 NGEF exchanges GTP for GDP on RHOA IEA Gallus gallus A0A1D5PII3 R-GGA-4093327 https://reactome.org/PathwayBrowser/#/R-GGA-4093327 EPHA binds TIAM1 IEA Gallus gallus A0A1D5PIK1 R-GGA-1678842 https://reactome.org/PathwayBrowser/#/R-GGA-1678842 Competitive inhibition of translation initiation by ISGylated 4EHP IEA Gallus gallus A0A1D5PIN2 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PIN2 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PIN2 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PIN2 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PIN3 R-GGA-6791222 https://reactome.org/PathwayBrowser/#/R-GGA-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Gallus gallus A0A1D5PIN3 R-GGA-6791227 https://reactome.org/PathwayBrowser/#/R-GGA-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Gallus gallus A0A1D5PIN6 R-GGA-3371518 https://reactome.org/PathwayBrowser/#/R-GGA-3371518 SIRT1 binds to HSF1 IEA Gallus gallus A0A1D5PIP2 R-GGA-159566 https://reactome.org/PathwayBrowser/#/R-GGA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Gallus gallus A0A1D5PIP2 R-GGA-159574 https://reactome.org/PathwayBrowser/#/R-GGA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Gallus gallus A0A1D5PIP2 R-GGA-9750001 https://reactome.org/PathwayBrowser/#/R-GGA-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Gallus gallus A0A1D5PIQ5 R-GGA-168053 https://reactome.org/PathwayBrowser/#/R-GGA-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Gallus gallus A0A1D5PIQ5 R-GGA-187688 https://reactome.org/PathwayBrowser/#/R-GGA-187688 p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 IEA Gallus gallus A0A1D5PIQ5 R-GGA-198669 https://reactome.org/PathwayBrowser/#/R-GGA-198669 p38MAPK phosphorylates MSK1 IEA Gallus gallus A0A1D5PIQ5 R-GGA-3229102 https://reactome.org/PathwayBrowser/#/R-GGA-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Gallus gallus A0A1D5PIQ5 R-GGA-3238999 https://reactome.org/PathwayBrowser/#/R-GGA-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 IEA Gallus gallus A0A1D5PIQ5 R-GGA-3239019 https://reactome.org/PathwayBrowser/#/R-GGA-3239019 Active p38 MAPK phosphorylates MAPKAPK5 IEA Gallus gallus A0A1D5PIQ5 R-GGA-428941 https://reactome.org/PathwayBrowser/#/R-GGA-428941 P2Y purinoceptor 1 activates MAP kinase p38 alpha IEA Gallus gallus A0A1D5PIQ5 R-GGA-428961 https://reactome.org/PathwayBrowser/#/R-GGA-428961 Phosphorylation of cPLA2 by MAPK p38 alpha IEA Gallus gallus A0A1D5PIQ5 R-GGA-432148 https://reactome.org/PathwayBrowser/#/R-GGA-432148 Fgr may phosphorylate p38 MAPK IEA Gallus gallus A0A1D5PIQ5 R-GGA-448955 https://reactome.org/PathwayBrowser/#/R-GGA-448955 Phosphorylation of MEF2 proteins by p38 IEA Gallus gallus A0A1D5PIQ5 R-GGA-448958 https://reactome.org/PathwayBrowser/#/R-GGA-448958 Nuclear translocation of p38 MAPK IEA Gallus gallus A0A1D5PIQ5 R-GGA-450222 https://reactome.org/PathwayBrowser/#/R-GGA-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 IEA Gallus gallus A0A1D5PIQ5 R-GGA-450257 https://reactome.org/PathwayBrowser/#/R-GGA-450257 Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 IEA Gallus gallus A0A1D5PIQ5 R-GGA-450333 https://reactome.org/PathwayBrowser/#/R-GGA-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Gallus gallus A0A1D5PIQ5 R-GGA-5218804 https://reactome.org/PathwayBrowser/#/R-GGA-5218804 p38 MAPK activation by VEGFR IEA Gallus gallus A0A1D5PIQ5 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PIQ5 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PIQ5 R-GGA-9626880 https://reactome.org/PathwayBrowser/#/R-GGA-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Gallus gallus A0A1D5PIQ5 R-GGA-9855910 https://reactome.org/PathwayBrowser/#/R-GGA-9855910 USF1 is phosphorylated by p-MAPK14 IEA Gallus gallus A0A1D5PIR0 R-GGA-1112666 https://reactome.org/PathwayBrowser/#/R-GGA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Gallus gallus A0A1D5PIR0 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus A0A1D5PIR0 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus A0A1D5PIR0 R-GGA-173626 https://reactome.org/PathwayBrowser/#/R-GGA-173626 Activation of C1r IEA Gallus gallus A0A1D5PIR0 R-GGA-173631 https://reactome.org/PathwayBrowser/#/R-GGA-173631 Activation of C1s IEA Gallus gallus A0A1D5PIR0 R-GGA-1861621 https://reactome.org/PathwayBrowser/#/R-GGA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Gallus gallus A0A1D5PIR0 R-GGA-199161 https://reactome.org/PathwayBrowser/#/R-GGA-199161 Fc gamma receptors interact with antigen-bound IgG IEA Gallus gallus A0A1D5PIR0 R-GGA-2029268 https://reactome.org/PathwayBrowser/#/R-GGA-2029268 Phosphorylation and activation of PLCG IEA Gallus gallus A0A1D5PIR0 R-GGA-2029270 https://reactome.org/PathwayBrowser/#/R-GGA-2029270 Recruitment of PLCgamma to membrane IEA Gallus gallus A0A1D5PIR0 R-GGA-2029271 https://reactome.org/PathwayBrowser/#/R-GGA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PIR0 R-GGA-2029272 https://reactome.org/PathwayBrowser/#/R-GGA-2029272 Release of PLCG from FCGR IEA Gallus gallus A0A1D5PIR0 R-GGA-2029273 https://reactome.org/PathwayBrowser/#/R-GGA-2029273 PI3K binds to p-6Y-SYK IEA Gallus gallus A0A1D5PIR0 R-GGA-2029451 https://reactome.org/PathwayBrowser/#/R-GGA-2029451 Activation of RAC1 by VAV IEA Gallus gallus A0A1D5PIR0 R-GGA-2029452 https://reactome.org/PathwayBrowser/#/R-GGA-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Gallus gallus A0A1D5PIR0 R-GGA-2029453 https://reactome.org/PathwayBrowser/#/R-GGA-2029453 Phosphorylation of VAV IEA Gallus gallus A0A1D5PIR0 R-GGA-2029455 https://reactome.org/PathwayBrowser/#/R-GGA-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Gallus gallus A0A1D5PIR0 R-GGA-2029457 https://reactome.org/PathwayBrowser/#/R-GGA-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Gallus gallus A0A1D5PIR0 R-GGA-2029458 https://reactome.org/PathwayBrowser/#/R-GGA-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Gallus gallus A0A1D5PIR0 R-GGA-2029459 https://reactome.org/PathwayBrowser/#/R-GGA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Gallus gallus A0A1D5PIR0 R-GGA-2029467 https://reactome.org/PathwayBrowser/#/R-GGA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Gallus gallus A0A1D5PIR0 R-GGA-2029476 https://reactome.org/PathwayBrowser/#/R-GGA-2029476 Role of myosins in phagosome formation IEA Gallus gallus A0A1D5PIR0 R-GGA-2197697 https://reactome.org/PathwayBrowser/#/R-GGA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Gallus gallus A0A1D5PIR0 R-GGA-2203516 https://reactome.org/PathwayBrowser/#/R-GGA-2203516 Alpha-1-Microglobulin is cleaved IEA Gallus gallus A0A1D5PIR0 R-GGA-8852266 https://reactome.org/PathwayBrowser/#/R-GGA-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Gallus gallus A0A1D5PIR0 R-GGA-8852481 https://reactome.org/PathwayBrowser/#/R-GGA-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Gallus gallus A0A1D5PIR0 R-GGA-8858428 https://reactome.org/PathwayBrowser/#/R-GGA-8858428 FCAMR binds IgA IEA Gallus gallus A0A1D5PIR0 R-GGA-9021306 https://reactome.org/PathwayBrowser/#/R-GGA-9021306 C1-Inh binds and inactivates C1r, C1s IEA Gallus gallus A0A1D5PIR0 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus A0A1D5PIR0 R-GGA-9724685 https://reactome.org/PathwayBrowser/#/R-GGA-9724685 IgE binds omalizumab IEA Gallus gallus A0A1D5PIR0 R-GGA-983696 https://reactome.org/PathwayBrowser/#/R-GGA-983696 The Immunoglobulin of the BCR binds antigen IEA Gallus gallus A0A1D5PIR0 R-GGA-983700 https://reactome.org/PathwayBrowser/#/R-GGA-983700 SYK binds the activated BCR IEA Gallus gallus A0A1D5PIR0 R-GGA-983703 https://reactome.org/PathwayBrowser/#/R-GGA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Gallus gallus A0A1D5PIR0 R-GGA-983707 https://reactome.org/PathwayBrowser/#/R-GGA-983707 SYK autophosphorylates at the activated BCR IEA Gallus gallus A0A1D5PIR1 R-GGA-380283 https://reactome.org/PathwayBrowser/#/R-GGA-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Gallus gallus A0A1D5PIR1 R-GGA-380508 https://reactome.org/PathwayBrowser/#/R-GGA-380508 Translocation of NuMA to the centrosomes IEA Gallus gallus A0A1D5PIR8 R-GGA-4084978 https://reactome.org/PathwayBrowser/#/R-GGA-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Gallus gallus A0A1D5PIR8 R-GGA-9845587 https://reactome.org/PathwayBrowser/#/R-GGA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Gallus gallus A0A1D5PIR9 R-GGA-8941234 https://reactome.org/PathwayBrowser/#/R-GGA-8941234 SH3PXD2A binds ADAM12,ADAM15,ADAM19 IEA Gallus gallus A0A1D5PIS1 R-GGA-211951 https://reactome.org/PathwayBrowser/#/R-GGA-211951 CYP1B1 4-hydroxylates EST17b IEA Gallus gallus A0A1D5PIS1 R-GGA-5692283 https://reactome.org/PathwayBrowser/#/R-GGA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Gallus gallus A0A1D5PIS1 R-GGA-76472 https://reactome.org/PathwayBrowser/#/R-GGA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Gallus gallus A0A1D5PIS1 R-GGA-8936851 https://reactome.org/PathwayBrowser/#/R-GGA-8936851 AHRR binds ARNT IEA Gallus gallus A0A1D5PIS1 R-GGA-8937177 https://reactome.org/PathwayBrowser/#/R-GGA-8937177 AHR:TCDD binds ARNT IEA Gallus gallus A0A1D5PIT4 R-GGA-2161620 https://reactome.org/PathwayBrowser/#/R-GGA-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Gallus gallus A0A1D5PIT4 R-GGA-5229273 https://reactome.org/PathwayBrowser/#/R-GGA-5229273 LCN2:2,5DHBA binds Fe3+ IEA Gallus gallus A0A1D5PIT4 R-GGA-5229283 https://reactome.org/PathwayBrowser/#/R-GGA-5229283 LCNs bind lipids IEA Gallus gallus A0A1D5PIT4 R-GGA-6798749 https://reactome.org/PathwayBrowser/#/R-GGA-6798749 Exocytosis of specific granule lumen proteins IEA Gallus gallus A0A1D5PIU2 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PIV1 R-GGA-1369017 https://reactome.org/PathwayBrowser/#/R-GGA-1369017 Activation of ATP sensitive Potassium channels in muscle cells IEA Gallus gallus A0A1D5PIV1 R-GGA-1454916 https://reactome.org/PathwayBrowser/#/R-GGA-1454916 The ABCC family mediates organic anion transport IEA Gallus gallus A0A1D5PIV1 R-GGA-5678261 https://reactome.org/PathwayBrowser/#/R-GGA-5678261 KCNJ11:ABCC9 transports K+ from extracellular region to cytosol IEA Gallus gallus A0A1D5PIV1 R-GGA-9691566 https://reactome.org/PathwayBrowser/#/R-GGA-9691566 KCNJ11:ABCC9 binds nicorandil IEA Gallus gallus A0A1D5PIV4 R-GGA-8986985 https://reactome.org/PathwayBrowser/#/R-GGA-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Gallus gallus A0A1D5PIV4 R-GGA-8987033 https://reactome.org/PathwayBrowser/#/R-GGA-8987033 p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 IEA Gallus gallus A0A1D5PIV4 R-GGA-8987266 https://reactome.org/PathwayBrowser/#/R-GGA-8987266 IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 IEA Gallus gallus A0A1D5PIV4 R-GGA-909718 https://reactome.org/PathwayBrowser/#/R-GGA-909718 Formation of p-STAT1 homodimer IEA Gallus gallus A0A1D5PIV4 R-GGA-909719 https://reactome.org/PathwayBrowser/#/R-GGA-909719 Recruitment of STAT2 to p-IFNAR1 IEA Gallus gallus A0A1D5PIV4 R-GGA-909720 https://reactome.org/PathwayBrowser/#/R-GGA-909720 IFN alpha/beta binds to IFNAR2 IEA Gallus gallus A0A1D5PIV4 R-GGA-909722 https://reactome.org/PathwayBrowser/#/R-GGA-909722 Release of p-STAT2:p-STAT1 dimer IEA Gallus gallus A0A1D5PIV4 R-GGA-909724 https://reactome.org/PathwayBrowser/#/R-GGA-909724 Recruitment of IFNAR1 IEA Gallus gallus A0A1D5PIV4 R-GGA-909729 https://reactome.org/PathwayBrowser/#/R-GGA-909729 Activation of JAK kinases IEA Gallus gallus A0A1D5PIV4 R-GGA-909730 https://reactome.org/PathwayBrowser/#/R-GGA-909730 Phosphorylation of INFAR1 by TYK2 IEA Gallus gallus A0A1D5PIV4 R-GGA-909732 https://reactome.org/PathwayBrowser/#/R-GGA-909732 Phosphorylation of STAT2 IEA Gallus gallus A0A1D5PIV4 R-GGA-9678935 https://reactome.org/PathwayBrowser/#/R-GGA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Gallus gallus A0A1D5PIV4 R-GGA-9696179 https://reactome.org/PathwayBrowser/#/R-GGA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Gallus gallus A0A1D5PIV4 R-GGA-9710959 https://reactome.org/PathwayBrowser/#/R-GGA-9710959 p-STAT1 dimer binds KPNA1 IEA Gallus gallus A0A1D5PIV4 R-GGA-9710963 https://reactome.org/PathwayBrowser/#/R-GGA-9710963 p-STAT1dimer:KPNA1 binds KPNB1 IEA Gallus gallus A0A1D5PIV4 R-GGA-997309 https://reactome.org/PathwayBrowser/#/R-GGA-997309 Dephosphorylation of STAT1 by SHP2 IEA Gallus gallus A0A1D5PIV4 R-GGA-997311 https://reactome.org/PathwayBrowser/#/R-GGA-997311 Dephosphorylation of TYK2 by PTP1B IEA Gallus gallus A0A1D5PIV4 R-GGA-997314 https://reactome.org/PathwayBrowser/#/R-GGA-997314 Dephosphorylation of JAK1 by SHP1 IEA Gallus gallus A0A1D5PIW7 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus A0A1D5PIW7 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus A0A1D5PIW7 R-GGA-399711 https://reactome.org/PathwayBrowser/#/R-GGA-399711 Activation of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5PIW7 R-GGA-399712 https://reactome.org/PathwayBrowser/#/R-GGA-399712 Activation of Ca permeable AMPA receptors IEA Gallus gallus A0A1D5PIW7 R-GGA-416639 https://reactome.org/PathwayBrowser/#/R-GGA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Gallus gallus A0A1D5PIW7 R-GGA-416985 https://reactome.org/PathwayBrowser/#/R-GGA-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Gallus gallus A0A1D5PIW7 R-GGA-420975 https://reactome.org/PathwayBrowser/#/R-GGA-420975 Ca impermeable AMPA receptor ligand binding IEA Gallus gallus A0A1D5PIW7 R-GGA-420977 https://reactome.org/PathwayBrowser/#/R-GGA-420977 Ca permeable AMPA receptor ligand binding IEA Gallus gallus A0A1D5PIW7 R-GGA-420980 https://reactome.org/PathwayBrowser/#/R-GGA-420980 Activation of Ca permeable AMPA receptors IEA Gallus gallus A0A1D5PIW7 R-GGA-421007 https://reactome.org/PathwayBrowser/#/R-GGA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5PIW7 R-GGA-438037 https://reactome.org/PathwayBrowser/#/R-GGA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5PIW7 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus A0A1D5PIW7 R-GGA-5694417 https://reactome.org/PathwayBrowser/#/R-GGA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Gallus gallus A0A1D5PIW7 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus A0A1D5PIW7 R-GGA-5694442 https://reactome.org/PathwayBrowser/#/R-GGA-5694442 CNIH2,3 bind GRIA1 IEA Gallus gallus A0A1D5PIW7 R-GGA-5694446 https://reactome.org/PathwayBrowser/#/R-GGA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Gallus gallus A0A1D5PIW7 R-GGA-5694522 https://reactome.org/PathwayBrowser/#/R-GGA-5694522 Inner coat assembly and cargo binding IEA Gallus gallus A0A1D5PIW7 R-GGA-5694527 https://reactome.org/PathwayBrowser/#/R-GGA-5694527 Loss of SAR1B GTPase IEA Gallus gallus A0A1D5PIW7 R-GGA-8849881 https://reactome.org/PathwayBrowser/#/R-GGA-8849881 SALM2 associate with AMPA and NMDA receptors IEA Gallus gallus A0A1D5PIX0 R-GGA-481007 https://reactome.org/PathwayBrowser/#/R-GGA-481007 Exocytosis of platelet alpha granule contents IEA Gallus gallus A0A1D5PIX6 R-GGA-8856630 https://reactome.org/PathwayBrowser/#/R-GGA-8856630 CIDEA:CIDEC binds lipid droplets IEA Gallus gallus A0A1D5PIX9 R-GGA-156808 https://reactome.org/PathwayBrowser/#/R-GGA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Gallus gallus A0A1D5PIX9 R-GGA-157849 https://reactome.org/PathwayBrowser/#/R-GGA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Gallus gallus A0A1D5PIX9 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus A0A1D5PIX9 R-GGA-72676 https://reactome.org/PathwayBrowser/#/R-GGA-72676 eIF3 and eIF1A bind to the 40S subunit IEA Gallus gallus A0A1D5PIX9 R-GGA-72691 https://reactome.org/PathwayBrowser/#/R-GGA-72691 Formation of the 43S pre-initiation complex IEA Gallus gallus A0A1D5PIX9 R-GGA-72697 https://reactome.org/PathwayBrowser/#/R-GGA-72697 Start codon recognition IEA Gallus gallus A0A1D5PIY0 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PIY0 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PIZ1 R-GGA-8940641 https://reactome.org/PathwayBrowser/#/R-GGA-8940641 THOP1 cleaves oligopeptide fragment (8-16aa) IEA Gallus gallus A0A1D5PIZ8 R-GGA-5626469 https://reactome.org/PathwayBrowser/#/R-GGA-5626469 GTP-bound RAC1 and CDC42 bind IQGAPs IEA Gallus gallus A0A1D5PIZ8 R-GGA-5626507 https://reactome.org/PathwayBrowser/#/R-GGA-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Gallus gallus A0A1D5PIZ8 R-GGA-5626549 https://reactome.org/PathwayBrowser/#/R-GGA-5626549 IQGAPs bind CALM1 IEA Gallus gallus A0A1D5PIZ8 R-GGA-5672972 https://reactome.org/PathwayBrowser/#/R-GGA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Gallus gallus A0A1D5PIZ8 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus A0A1D5PIZ8 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus A0A1D5PIZ8 R-GGA-5672980 https://reactome.org/PathwayBrowser/#/R-GGA-5672980 Dissociation of RAS:RAF complex IEA Gallus gallus A0A1D5PIZ8 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PIZ8 R-GGA-9013009 https://reactome.org/PathwayBrowser/#/R-GGA-9013009 RHOA binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PIZ8 R-GGA-9013110 https://reactome.org/PathwayBrowser/#/R-GGA-9013110 RHOC binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PIZ8 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PIZ8 R-GGA-9014294 https://reactome.org/PathwayBrowser/#/R-GGA-9014294 RAC2 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PIZ8 R-GGA-9018746 https://reactome.org/PathwayBrowser/#/R-GGA-9018746 RHOQ binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PIZ8 R-GGA-9018766 https://reactome.org/PathwayBrowser/#/R-GGA-9018766 RHOU binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PIZ8 R-GGA-9018794 https://reactome.org/PathwayBrowser/#/R-GGA-9018794 RHOV binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PIZ8 R-GGA-9657599 https://reactome.org/PathwayBrowser/#/R-GGA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Gallus gallus A0A1D5PIZ8 R-GGA-9657603 https://reactome.org/PathwayBrowser/#/R-GGA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Gallus gallus A0A1D5PIZ8 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus A0A1D5PIZ8 R-GGA-9657608 https://reactome.org/PathwayBrowser/#/R-GGA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Gallus gallus A0A1D5PJ10 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus A0A1D5PJ10 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus A0A1D5PJ30 R-GGA-190682 https://reactome.org/PathwayBrowser/#/R-GGA-190682 Connexin synthesis (generic) IEA Gallus gallus A0A1D5PJ47 R-GGA-975829 https://reactome.org/PathwayBrowser/#/R-GGA-975829 Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 IEA Gallus gallus A0A1D5PJ49 R-GGA-166038 https://reactome.org/PathwayBrowser/#/R-GGA-166038 GPI-bound CD14 binds LPS IEA Gallus gallus A0A1D5PJ49 R-GGA-166041 https://reactome.org/PathwayBrowser/#/R-GGA-166041 Transfer of LPS onto TLR4 IEA Gallus gallus A0A1D5PJ49 R-GGA-166175 https://reactome.org/PathwayBrowser/#/R-GGA-166175 TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) IEA Gallus gallus A0A1D5PJ49 R-GGA-166245 https://reactome.org/PathwayBrowser/#/R-GGA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Gallus gallus A0A1D5PJ49 R-GGA-166271 https://reactome.org/PathwayBrowser/#/R-GGA-166271 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 IEA Gallus gallus A0A1D5PJ49 R-GGA-168915 https://reactome.org/PathwayBrowser/#/R-GGA-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex IEA Gallus gallus A0A1D5PJ49 R-GGA-168921 https://reactome.org/PathwayBrowser/#/R-GGA-168921 TRIF:activated TLR3/TLR4 complex recruits RIP1 IEA Gallus gallus A0A1D5PJ49 R-GGA-169719 https://reactome.org/PathwayBrowser/#/R-GGA-169719 Secreted CD14 binds LPS IEA Gallus gallus A0A1D5PJ49 R-GGA-2201293 https://reactome.org/PathwayBrowser/#/R-GGA-2201293 Endocytosis of TLR4:LY96:LPS:CD14 IEA Gallus gallus A0A1D5PJ49 R-GGA-2201338 https://reactome.org/PathwayBrowser/#/R-GGA-2201338 TRAF3 binds TICAM1:activated TLR4 complex IEA Gallus gallus A0A1D5PJ49 R-GGA-2213017 https://reactome.org/PathwayBrowser/#/R-GGA-2213017 Auto-ubiquitination of TRAF3 IEA Gallus gallus A0A1D5PJ49 R-GGA-2559439 https://reactome.org/PathwayBrowser/#/R-GGA-2559439 CD14:LPS binds CR3 IEA Gallus gallus A0A1D5PJ49 R-GGA-2562541 https://reactome.org/PathwayBrowser/#/R-GGA-2562541 TLR4-induced ripoptosome assembly IEA Gallus gallus A0A1D5PJ49 R-GGA-2562564 https://reactome.org/PathwayBrowser/#/R-GGA-2562564 Caspase-8 processing within TLR4 complex IEA Gallus gallus A0A1D5PJ49 R-GGA-450358 https://reactome.org/PathwayBrowser/#/R-GGA-450358 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation IEA Gallus gallus A0A1D5PJ49 R-GGA-5362486 https://reactome.org/PathwayBrowser/#/R-GGA-5362486 TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4 IEA Gallus gallus A0A1D5PJ49 R-GGA-5362500 https://reactome.org/PathwayBrowser/#/R-GGA-5362500 TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Gallus gallus A0A1D5PJ49 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PJ49 R-GGA-8869694 https://reactome.org/PathwayBrowser/#/R-GGA-8869694 oxPL binds CD14 IEA Gallus gallus A0A1D5PJ49 R-GGA-936947 https://reactome.org/PathwayBrowser/#/R-GGA-936947 Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex IEA Gallus gallus A0A1D5PJ49 R-GGA-936951 https://reactome.org/PathwayBrowser/#/R-GGA-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Gallus gallus A0A1D5PJ49 R-GGA-936952 https://reactome.org/PathwayBrowser/#/R-GGA-936952 Auto ubiquitination of TRAF6 bound to the activated TLR4 complex IEA Gallus gallus A0A1D5PJ49 R-GGA-936985 https://reactome.org/PathwayBrowser/#/R-GGA-936985 Activated TLR4:TICAM1 recruits TRAF6 IEA Gallus gallus A0A1D5PJ49 R-GGA-937075 https://reactome.org/PathwayBrowser/#/R-GGA-937075 Phosphorylated TAK1 leaves activated TLR receptor complex IEA Gallus gallus A0A1D5PJ49 R-GGA-9823904 https://reactome.org/PathwayBrowser/#/R-GGA-9823904 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Gallus gallus A0A1D5PJ49 R-GGA-9823906 https://reactome.org/PathwayBrowser/#/R-GGA-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Gallus gallus A0A1D5PJ49 R-GGA-9823910 https://reactome.org/PathwayBrowser/#/R-GGA-9823910 Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Gallus gallus A0A1D5PJ49 R-GGA-9823932 https://reactome.org/PathwayBrowser/#/R-GGA-9823932 Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Gallus gallus A0A1D5PJ49 R-GGA-9823934 https://reactome.org/PathwayBrowser/#/R-GGA-9823934 OPTN binds TBK1 within the activated TLR4 complex IEA Gallus gallus A0A1D5PJ49 R-GGA-9823939 https://reactome.org/PathwayBrowser/#/R-GGA-9823939 IKKε (IKBKE) is ubiquitinated within the activated TLR4 IEA Gallus gallus A0A1D5PJ49 R-GGA-9824882 https://reactome.org/PathwayBrowser/#/R-GGA-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Gallus gallus A0A1D5PJ79 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5PJ79 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1D5PJ92 R-GGA-6782069 https://reactome.org/PathwayBrowser/#/R-GGA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Gallus gallus A0A1D5PJ92 R-GGA-6782131 https://reactome.org/PathwayBrowser/#/R-GGA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5PJ92 R-GGA-6782138 https://reactome.org/PathwayBrowser/#/R-GGA-6782138 ERCC5 and RPA bind TC-NER site IEA Gallus gallus A0A1D5PJ92 R-GGA-6782204 https://reactome.org/PathwayBrowser/#/R-GGA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Gallus gallus A0A1D5PJ92 R-GGA-6782208 https://reactome.org/PathwayBrowser/#/R-GGA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Gallus gallus A0A1D5PJ92 R-GGA-6782211 https://reactome.org/PathwayBrowser/#/R-GGA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Gallus gallus A0A1D5PJ92 R-GGA-6782227 https://reactome.org/PathwayBrowser/#/R-GGA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Gallus gallus A0A1D5PJ92 R-GGA-9684118 https://reactome.org/PathwayBrowser/#/R-GGA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5PJ96 R-GGA-5692480 https://reactome.org/PathwayBrowser/#/R-GGA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Gallus gallus A0A1D5PJA5 R-GGA-9023626 https://reactome.org/PathwayBrowser/#/R-GGA-9023626 DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) IEA Gallus gallus A0A1D5PJA5 R-GGA-9023627 https://reactome.org/PathwayBrowser/#/R-GGA-9023627 DPP4(1-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) IEA Gallus gallus A0A1D5PJA5 R-GGA-9023632 https://reactome.org/PathwayBrowser/#/R-GGA-9023632 DPP4(39-766) hydrolyzes Glucagon-like Peptide-1 (GLP-1) IEA Gallus gallus A0A1D5PJA5 R-GGA-9023633 https://reactome.org/PathwayBrowser/#/R-GGA-9023633 DPP4(1-766) hydrolyzes Glucagon-like Peptide-1 (GLP-1) IEA Gallus gallus A0A1D5PJA5 R-GGA-9709179 https://reactome.org/PathwayBrowser/#/R-GGA-9709179 DPP4 binds DPP4 inhibitors IEA Gallus gallus A0A1D5PJC2 R-GGA-432164 https://reactome.org/PathwayBrowser/#/R-GGA-432164 Ca2+ influx into the post-synaptic cell IEA Gallus gallus A0A1D5PJC2 R-GGA-438037 https://reactome.org/PathwayBrowser/#/R-GGA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5PJC2 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5PJC6 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5PJD5 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PJD5 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PJD5 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PJD5 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PJE0 R-GGA-913675 https://reactome.org/PathwayBrowser/#/R-GGA-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Gallus gallus A0A1D5PJF2 R-GGA-159443 https://reactome.org/PathwayBrowser/#/R-GGA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate IEA Gallus gallus A0A1D5PJF2 R-GGA-159567 https://reactome.org/PathwayBrowser/#/R-GGA-159567 ACSM2B-like proteins transform ST to ST-CoA IEA Gallus gallus A0A1D5PJF2 R-GGA-177157 https://reactome.org/PathwayBrowser/#/R-GGA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate IEA Gallus gallus A0A1D5PJF2 R-GGA-9749971 https://reactome.org/PathwayBrowser/#/R-GGA-9749971 ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA IEA Gallus gallus A0A1D5PJI3 R-GGA-202706 https://reactome.org/PathwayBrowser/#/R-GGA-202706 Integrin alpha4beta1 binds JAM2:JAM3 IEA Gallus gallus A0A1D5PJI3 R-GGA-202709 https://reactome.org/PathwayBrowser/#/R-GGA-202709 JAM2 dimerises IEA Gallus gallus A0A1D5PJI3 R-GGA-202721 https://reactome.org/PathwayBrowser/#/R-GGA-202721 JAM2 binds JAM3 IEA Gallus gallus A0A1D5PJJ1 R-GGA-212222 https://reactome.org/PathwayBrowser/#/R-GGA-212222 PRC2 recruits DNA methyltransferases IEA Gallus gallus A0A1D5PJJ1 R-GGA-212269 https://reactome.org/PathwayBrowser/#/R-GGA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Gallus gallus A0A1D5PJJ1 R-GGA-4655374 https://reactome.org/PathwayBrowser/#/R-GGA-4655374 SUMOylation of DNMT3B with SUMO1 IEA Gallus gallus A0A1D5PJJ4 R-GGA-6805943 https://reactome.org/PathwayBrowser/#/R-GGA-6805943 S100A1 binds TLR4:LY96 IEA Gallus gallus A0A1D5PJJ8 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5PJJ8 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5PJJ8 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5PJJ8 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5PJJ8 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5PJJ8 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PJJ8 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PJJ8 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5PJJ8 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5PJM1 R-GGA-1602368 https://reactome.org/PathwayBrowser/#/R-GGA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Gallus gallus A0A1D5PJM1 R-GGA-1602374 https://reactome.org/PathwayBrowser/#/R-GGA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Gallus gallus A0A1D5PJM1 R-GGA-1602377 https://reactome.org/PathwayBrowser/#/R-GGA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Gallus gallus A0A1D5PJM1 R-GGA-1602398 https://reactome.org/PathwayBrowser/#/R-GGA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Gallus gallus A0A1D5PJM1 R-GGA-1602417 https://reactome.org/PathwayBrowser/#/R-GGA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Gallus gallus A0A1D5PJM1 R-GGA-1602446 https://reactome.org/PathwayBrowser/#/R-GGA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Gallus gallus A0A1D5PJM6 R-GGA-111439 https://reactome.org/PathwayBrowser/#/R-GGA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Gallus gallus A0A1D5PJM6 R-GGA-158441 https://reactome.org/PathwayBrowser/#/R-GGA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PJM6 R-GGA-158447 https://reactome.org/PathwayBrowser/#/R-GGA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Gallus gallus A0A1D5PJM6 R-GGA-158481 https://reactome.org/PathwayBrowser/#/R-GGA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PJM6 R-GGA-158484 https://reactome.org/PathwayBrowser/#/R-GGA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Gallus gallus A0A1D5PJM6 R-GGA-159046 https://reactome.org/PathwayBrowser/#/R-GGA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Gallus gallus A0A1D5PJM6 R-GGA-159050 https://reactome.org/PathwayBrowser/#/R-GGA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Gallus gallus A0A1D5PJM6 R-GGA-170825 https://reactome.org/PathwayBrowser/#/R-GGA-170825 NPC exports GCK1 from nucleus IEA Gallus gallus A0A1D5PJM6 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1D5PJM6 R-GGA-2990880 https://reactome.org/PathwayBrowser/#/R-GGA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Gallus gallus A0A1D5PJM6 R-GGA-2990882 https://reactome.org/PathwayBrowser/#/R-GGA-2990882 CDK1 phosphorylates NUP98 IEA Gallus gallus A0A1D5PJM6 R-GGA-4551649 https://reactome.org/PathwayBrowser/#/R-GGA-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Gallus gallus A0A1D5PJM6 R-GGA-4551679 https://reactome.org/PathwayBrowser/#/R-GGA-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Gallus gallus A0A1D5PJM6 R-GGA-4615872 https://reactome.org/PathwayBrowser/#/R-GGA-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Gallus gallus A0A1D5PJM6 R-GGA-4615987 https://reactome.org/PathwayBrowser/#/R-GGA-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Gallus gallus A0A1D5PJM6 R-GGA-4655355 https://reactome.org/PathwayBrowser/#/R-GGA-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Gallus gallus A0A1D5PJM6 R-GGA-5228523 https://reactome.org/PathwayBrowser/#/R-GGA-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Gallus gallus A0A1D5PJM6 R-GGA-5578744 https://reactome.org/PathwayBrowser/#/R-GGA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Gallus gallus A0A1D5PJM6 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1D5PJM6 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1D5PJM6 R-GGA-77587 https://reactome.org/PathwayBrowser/#/R-GGA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Gallus gallus A0A1D5PJP5 R-GGA-8848247 https://reactome.org/PathwayBrowser/#/R-GGA-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA IEA Gallus gallus A0A1D5PJP5 R-GGA-9013009 https://reactome.org/PathwayBrowser/#/R-GGA-9013009 RHOA binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PJP5 R-GGA-9013110 https://reactome.org/PathwayBrowser/#/R-GGA-9013110 RHOC binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PJP5 R-GGA-9603775 https://reactome.org/PathwayBrowser/#/R-GGA-9603775 PEX3:PEX19:class I PMP dissociates IEA Gallus gallus A0A1D5PJP5 R-GGA-9603784 https://reactome.org/PathwayBrowser/#/R-GGA-9603784 PEX19:class I PMP binds PEX3 IEA Gallus gallus A0A1D5PJP5 R-GGA-9603804 https://reactome.org/PathwayBrowser/#/R-GGA-9603804 PEX19 binds class I peroxisomal membrane proteins IEA Gallus gallus A0A1D5PJP6 R-GGA-1504186 https://reactome.org/PathwayBrowser/#/R-GGA-1504186 DVL recruits GSK3beta:AXIN1 to the receptor complex IEA Gallus gallus A0A1D5PJP6 R-GGA-201677 https://reactome.org/PathwayBrowser/#/R-GGA-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Gallus gallus A0A1D5PJP6 R-GGA-3769397 https://reactome.org/PathwayBrowser/#/R-GGA-3769397 SOST binds LRP5/6 IEA Gallus gallus A0A1D5PJP6 R-GGA-4641236 https://reactome.org/PathwayBrowser/#/R-GGA-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Gallus gallus A0A1D5PJP6 R-GGA-4641249 https://reactome.org/PathwayBrowser/#/R-GGA-4641249 ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex IEA Gallus gallus A0A1D5PJP6 R-GGA-4641253 https://reactome.org/PathwayBrowser/#/R-GGA-4641253 ZNRF3 ubiquitinates FZD to promote its downregulation IEA Gallus gallus A0A1D5PJP6 R-GGA-5368596 https://reactome.org/PathwayBrowser/#/R-GGA-5368596 WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 IEA Gallus gallus A0A1D5PJQ2 R-GGA-376419 https://reactome.org/PathwayBrowser/#/R-GGA-376419 Formation of NR-MED1 Coactivator Complex IEA Gallus gallus A0A1D5PJQ2 R-GGA-382096 https://reactome.org/PathwayBrowser/#/R-GGA-382096 Formation of NR-NCOR Corepressor Complex IEA Gallus gallus A0A1D5PJQ2 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus A0A1D5PJQ2 R-GGA-400183 https://reactome.org/PathwayBrowser/#/R-GGA-400183 PPARA:RXRA binds Corepressors of PPARA IEA Gallus gallus A0A1D5PJQ2 R-GGA-400204 https://reactome.org/PathwayBrowser/#/R-GGA-400204 PPARA binds RXRA IEA Gallus gallus A0A1D5PJQ2 R-GGA-4341070 https://reactome.org/PathwayBrowser/#/R-GGA-4341070 PIAS4 SUMOylates PPARA with SUMO1 IEA Gallus gallus A0A1D5PJQ2 R-GGA-9734475 https://reactome.org/PathwayBrowser/#/R-GGA-9734475 PPARA binds fibrates IEA Gallus gallus A0A1D5PJQ8 R-GGA-8848993 https://reactome.org/PathwayBrowser/#/R-GGA-8848993 Phosphorylated KHDRBS1 translocates to the cytosol IEA Gallus gallus A0A1D5PJR2 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PJR5 R-GGA-9825759 https://reactome.org/PathwayBrowser/#/R-GGA-9825759 MAPK-dependent phosphorylation of KARS IEA Gallus gallus A0A1D5PJS0 R-GGA-5696872 https://reactome.org/PathwayBrowser/#/R-GGA-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Gallus gallus A0A1D5PJS0 R-GGA-9674127 https://reactome.org/PathwayBrowser/#/R-GGA-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Gallus gallus A0A1D5PJS0 R-GGA-9674131 https://reactome.org/PathwayBrowser/#/R-GGA-9674131 USP30 binds ATM dimer:Ub-p-PEX5 IEA Gallus gallus A0A1D5PJT4 R-GGA-6801195 https://reactome.org/PathwayBrowser/#/R-GGA-6801195 STEAP3 binds BNIP3L IEA Gallus gallus A0A1D5PJT4 R-GGA-9018746 https://reactome.org/PathwayBrowser/#/R-GGA-9018746 RHOQ binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PJT4 R-GGA-917811 https://reactome.org/PathwayBrowser/#/R-GGA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Gallus gallus A0A1D5PJT4 R-GGA-9693125 https://reactome.org/PathwayBrowser/#/R-GGA-9693125 RHOF binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PJT4 R-GGA-9693198 https://reactome.org/PathwayBrowser/#/R-GGA-9693198 RHOD binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PJV0 R-GGA-9821235 https://reactome.org/PathwayBrowser/#/R-GGA-9821235 HCFC1, HCFC2 bind the MLL1:MEN1 complex IEA Gallus gallus A0A1D5PJV7 R-GGA-391151 https://reactome.org/PathwayBrowser/#/R-GGA-391151 p-4Y-SIRPA:CD47:SKAP2 binds FYB IEA Gallus gallus A0A1D5PJV7 R-GGA-391157 https://reactome.org/PathwayBrowser/#/R-GGA-391157 p-4Y-SIRPA:CD47 binds SKAP2 IEA Gallus gallus A0A1D5PJW1 R-GGA-139970 https://reactome.org/PathwayBrowser/#/R-GGA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Gallus gallus A0A1D5PJW4 R-GGA-1168640 https://reactome.org/PathwayBrowser/#/R-GGA-1168640 Ubiquitinated IkB is degraded IEA Gallus gallus A0A1D5PJW4 R-GGA-1234159 https://reactome.org/PathwayBrowser/#/R-GGA-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Gallus gallus A0A1D5PJW4 R-GGA-1236970 https://reactome.org/PathwayBrowser/#/R-GGA-1236970 Proteasomal clevage of exogenous antigen (26S proteasome catalyst) IEA Gallus gallus A0A1D5PJW4 R-GGA-1504193 https://reactome.org/PathwayBrowser/#/R-GGA-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-174058 https://reactome.org/PathwayBrowser/#/R-GGA-174058 Degradation of multiubiquitinated Cdh1 IEA Gallus gallus A0A1D5PJW4 R-GGA-174105 https://reactome.org/PathwayBrowser/#/R-GGA-174105 Degradation of multiubiquitinated cell cycle proteins IEA Gallus gallus A0A1D5PJW4 R-GGA-174202 https://reactome.org/PathwayBrowser/#/R-GGA-174202 Degradation of multiubiquitinated Securin IEA Gallus gallus A0A1D5PJW4 R-GGA-174255 https://reactome.org/PathwayBrowser/#/R-GGA-174255 Degradation multiubiquitinated Cyclin A IEA Gallus gallus A0A1D5PJW4 R-GGA-187574 https://reactome.org/PathwayBrowser/#/R-GGA-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-188191 https://reactome.org/PathwayBrowser/#/R-GGA-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Gallus gallus A0A1D5PJW4 R-GGA-209061 https://reactome.org/PathwayBrowser/#/R-GGA-209061 Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex IEA Gallus gallus A0A1D5PJW4 R-GGA-2130282 https://reactome.org/PathwayBrowser/#/R-GGA-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-264458 https://reactome.org/PathwayBrowser/#/R-GGA-264458 Proteasome mediated degradation of COP1 IEA Gallus gallus A0A1D5PJW4 R-GGA-353125 https://reactome.org/PathwayBrowser/#/R-GGA-353125 26S proteosome degrades ODC holoenzyme complex IEA Gallus gallus A0A1D5PJW4 R-GGA-3640874 https://reactome.org/PathwayBrowser/#/R-GGA-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-450466 https://reactome.org/PathwayBrowser/#/R-GGA-450466 AUF1:mRNA complex is destroyed IEA Gallus gallus A0A1D5PJW4 R-GGA-4608855 https://reactome.org/PathwayBrowser/#/R-GGA-4608855 PRICKLE1 is degraded by the proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-4641256 https://reactome.org/PathwayBrowser/#/R-GGA-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-5362448 https://reactome.org/PathwayBrowser/#/R-GGA-5362448 Hh C-terminal fragments are degraded by the proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-5607724 https://reactome.org/PathwayBrowser/#/R-GGA-5607724 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex IEA Gallus gallus A0A1D5PJW4 R-GGA-5610754 https://reactome.org/PathwayBrowser/#/R-GGA-5610754 GLI3 is partially degraded by the proteasome to yield the GLI3 repressor IEA Gallus gallus A0A1D5PJW4 R-GGA-5610758 https://reactome.org/PathwayBrowser/#/R-GGA-5610758 GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP IEA Gallus gallus A0A1D5PJW4 R-GGA-5610760 https://reactome.org/PathwayBrowser/#/R-GGA-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Gallus gallus A0A1D5PJW4 R-GGA-5635854 https://reactome.org/PathwayBrowser/#/R-GGA-5635854 GLI2,3 are degraded by the proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-5635868 https://reactome.org/PathwayBrowser/#/R-GGA-5635868 ub-GLI is degraded by the proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-5658430 https://reactome.org/PathwayBrowser/#/R-GGA-5658430 NF1 is degraded by the proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-5665854 https://reactome.org/PathwayBrowser/#/R-GGA-5665854 ADRM1:26S proteaseome binds UCHL5 IEA Gallus gallus A0A1D5PJW4 R-GGA-5665871 https://reactome.org/PathwayBrowser/#/R-GGA-5665871 ADRM1 binds 26S proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-5668481 https://reactome.org/PathwayBrowser/#/R-GGA-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Gallus gallus A0A1D5PJW4 R-GGA-5668520 https://reactome.org/PathwayBrowser/#/R-GGA-5668520 26Sproteasome degrades K48polyUb-NIK IEA Gallus gallus A0A1D5PJW4 R-GGA-5687112 https://reactome.org/PathwayBrowser/#/R-GGA-5687112 MAPK6 is degraded by the 26S proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-5689539 https://reactome.org/PathwayBrowser/#/R-GGA-5689539 ADRM1:26S proteaseome binds USP14 IEA Gallus gallus A0A1D5PJW4 R-GGA-68825 https://reactome.org/PathwayBrowser/#/R-GGA-68825 Ubiquitinated geminin is degraded by the proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-68948 https://reactome.org/PathwayBrowser/#/R-GGA-68948 Ubiquitinated Orc1 is degraded by the proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-69016 https://reactome.org/PathwayBrowser/#/R-GGA-69016 Ubiquitinated Cdc6 is degraded by the proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-69600 https://reactome.org/PathwayBrowser/#/R-GGA-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Gallus gallus A0A1D5PJW4 R-GGA-75825 https://reactome.org/PathwayBrowser/#/R-GGA-75825 Proteasome mediated degradation of Cyclin D1 IEA Gallus gallus A0A1D5PJW4 R-GGA-8850992 https://reactome.org/PathwayBrowser/#/R-GGA-8850992 Proteasome degrades polyubiquitinated PTEN IEA Gallus gallus A0A1D5PJW4 R-GGA-8854044 https://reactome.org/PathwayBrowser/#/R-GGA-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Gallus gallus A0A1D5PJW4 R-GGA-8854071 https://reactome.org/PathwayBrowser/#/R-GGA-8854071 Proteasome-mediated degradation of PolyUb-FBXL7 IEA Gallus gallus A0A1D5PJW4 R-GGA-8866553 https://reactome.org/PathwayBrowser/#/R-GGA-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-8932355 https://reactome.org/PathwayBrowser/#/R-GGA-8932355 26S proteasome degrades Ub-NFE2L2 IEA Gallus gallus A0A1D5PJW4 R-GGA-8939801 https://reactome.org/PathwayBrowser/#/R-GGA-8939801 26S proteasome degrades PolyUb-RUNX2 IEA Gallus gallus A0A1D5PJW4 R-GGA-8952408 https://reactome.org/PathwayBrowser/#/R-GGA-8952408 Polyubiquitinated RUNX3 is degraded by the proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-8956140 https://reactome.org/PathwayBrowser/#/R-GGA-8956140 NEDD8 and UBD bind NUB1 and the 26S proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-8956184 https://reactome.org/PathwayBrowser/#/R-GGA-8956184 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates IEA Gallus gallus A0A1D5PJW4 R-GGA-8957265 https://reactome.org/PathwayBrowser/#/R-GGA-8957265 26S proteasome degrades TP73 polyubiquitinated by ITCH IEA Gallus gallus A0A1D5PJW4 R-GGA-9755303 https://reactome.org/PathwayBrowser/#/R-GGA-9755303 26S proteasome degrades HIFalpha IEA Gallus gallus A0A1D5PJW4 R-GGA-9755306 https://reactome.org/PathwayBrowser/#/R-GGA-9755306 ub UBXN7 is degraded by the 26S proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-9762096 https://reactome.org/PathwayBrowser/#/R-GGA-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Gallus gallus A0A1D5PJW4 R-GGA-983150 https://reactome.org/PathwayBrowser/#/R-GGA-983150 Proteasomal cleavage of substrate IEA Gallus gallus A0A1D5PJW4 R-GGA-9907912 https://reactome.org/PathwayBrowser/#/R-GGA-9907912 Formation of the outer ring of the 20S core particle IEA Gallus gallus A0A1D5PJW4 R-GGA-9907919 https://reactome.org/PathwayBrowser/#/R-GGA-9907919 Formation of the preholoproteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-9907940 https://reactome.org/PathwayBrowser/#/R-GGA-9907940 Formation of the preholothymoproteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-9907941 https://reactome.org/PathwayBrowser/#/R-GGA-9907941 Fromation of the preholoimmunoproteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-9908052 https://reactome.org/PathwayBrowser/#/R-GGA-9908052 PSMG1:PSMG2 dimer binds the 20S core particle outer ring IEA Gallus gallus A0A1D5PJW4 R-GGA-9908069 https://reactome.org/PathwayBrowser/#/R-GGA-9908069 POMP binds the 20S core particle outer ring IEA Gallus gallus A0A1D5PJW4 R-GGA-9908721 https://reactome.org/PathwayBrowser/#/R-GGA-9908721 Formation of the PA28gamma-20S proteasome IEA Gallus gallus A0A1D5PJW4 R-GGA-9912636 https://reactome.org/PathwayBrowser/#/R-GGA-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Gallus gallus A0A1D5PJW4 R-GGA-9934893 https://reactome.org/PathwayBrowser/#/R-GGA-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 IEA Gallus gallus A0A1D5PJY1 R-GGA-392051 https://reactome.org/PathwayBrowser/#/R-GGA-392051 Recruitment of Grb2 to pFAK:NCAM1 IEA Gallus gallus A0A1D5PJY1 R-GGA-392053 https://reactome.org/PathwayBrowser/#/R-GGA-392053 SOS binds Grb2 bound to pFAK:NCAM1 IEA Gallus gallus A0A1D5PJY1 R-GGA-392054 https://reactome.org/PathwayBrowser/#/R-GGA-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Gallus gallus A0A1D5PJY1 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5PJY1 R-GGA-6807877 https://reactome.org/PathwayBrowser/#/R-GGA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Gallus gallus A0A1D5PJY1 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1D5PJY1 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5PJY1 R-GGA-6809011 https://reactome.org/PathwayBrowser/#/R-GGA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Gallus gallus A0A1D5PJY1 R-GGA-9018766 https://reactome.org/PathwayBrowser/#/R-GGA-9018766 RHOU binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PJY1 R-GGA-9018794 https://reactome.org/PathwayBrowser/#/R-GGA-9018794 RHOV binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PJY4 R-GGA-5693681 https://reactome.org/PathwayBrowser/#/R-GGA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Gallus gallus A0A1D5PJZ1 R-GGA-203797 https://reactome.org/PathwayBrowser/#/R-GGA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Gallus gallus A0A1D5PJZ5 R-GGA-5334794 https://reactome.org/PathwayBrowser/#/R-GGA-5334794 FABPs bind LCFAs IEA Gallus gallus A0A1D5PJZ8 R-GGA-429860 https://reactome.org/PathwayBrowser/#/R-GGA-429860 DCP1-DCP2 complex decaps mRNA IEA Gallus gallus A0A1D5PJZ8 R-GGA-429978 https://reactome.org/PathwayBrowser/#/R-GGA-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Gallus gallus A0A1D5PK08 R-GGA-164832 https://reactome.org/PathwayBrowser/#/R-GGA-164832 ATPase synthesizes ATP IEA Gallus gallus A0A1D5PK08 R-GGA-164834 https://reactome.org/PathwayBrowser/#/R-GGA-164834 Enzyme-bound ATP is released IEA Gallus gallus A0A1D5PK08 R-GGA-164840 https://reactome.org/PathwayBrowser/#/R-GGA-164840 ADP and Pi bind to ATPase IEA Gallus gallus A0A1D5PK08 R-GGA-8949580 https://reactome.org/PathwayBrowser/#/R-GGA-8949580 F1Fo ATP synthase dimerizes IEA Gallus gallus A0A1D5PK13 R-GGA-8865482 https://reactome.org/PathwayBrowser/#/R-GGA-8865482 KMT2A (MLL) binds RUNX1 IEA Gallus gallus A0A1D5PK13 R-GGA-8936481 https://reactome.org/PathwayBrowser/#/R-GGA-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Gallus gallus A0A1D5PK13 R-GGA-8936621 https://reactome.org/PathwayBrowser/#/R-GGA-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Gallus gallus A0A1D5PK13 R-GGA-8937016 https://reactome.org/PathwayBrowser/#/R-GGA-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Gallus gallus A0A1D5PK13 R-GGA-8937050 https://reactome.org/PathwayBrowser/#/R-GGA-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Gallus gallus A0A1D5PK13 R-GGA-9675026 https://reactome.org/PathwayBrowser/#/R-GGA-9675026 Formation of the MLL1 complex IEA Gallus gallus A0A1D5PK13 R-GGA-9818574 https://reactome.org/PathwayBrowser/#/R-GGA-9818574 TASP1 cleaves KMT2A IEA Gallus gallus A0A1D5PK13 R-GGA-9818576 https://reactome.org/PathwayBrowser/#/R-GGA-9818576 Cleaved KMT2A dimers translocate to the nucleus IEA Gallus gallus A0A1D5PK13 R-GGA-9821235 https://reactome.org/PathwayBrowser/#/R-GGA-9821235 HCFC1, HCFC2 bind the MLL1:MEN1 complex IEA Gallus gallus A0A1D5PK13 R-GGA-9821368 https://reactome.org/PathwayBrowser/#/R-GGA-9821368 AKAP8L binds MLL1 complex IEA Gallus gallus A0A1D5PK16 R-GGA-2467775 https://reactome.org/PathwayBrowser/#/R-GGA-2467775 Autocleavage of ESPL1 (Separase) IEA Gallus gallus A0A1D5PK16 R-GGA-2467798 https://reactome.org/PathwayBrowser/#/R-GGA-2467798 PTTG1 (Securin) sequesters ESPL1 (Separase) IEA Gallus gallus A0A1D5PK16 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5PK19 R-GGA-3134946 https://reactome.org/PathwayBrowser/#/R-GGA-3134946 DDX41 ubiquitination by TRIM21 IEA Gallus gallus A0A1D5PK19 R-GGA-9759154 https://reactome.org/PathwayBrowser/#/R-GGA-9759154 TRIM21 ubiquitinates SQSTM1 IEA Gallus gallus A0A1D5PK19 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PK19 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PK19 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PK19 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PK20 R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus A0A1D5PK20 R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus A0A1D5PK20 R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus A0A1D5PK20 R-GGA-194187 https://reactome.org/PathwayBrowser/#/R-GGA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Gallus gallus A0A1D5PK20 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus A0A1D5PK20 R-GGA-5340251 https://reactome.org/PathwayBrowser/#/R-GGA-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Gallus gallus A0A1D5PK20 R-GGA-5579023 https://reactome.org/PathwayBrowser/#/R-GGA-5579023 NCOA2(869-1464) binds KAT6A(1-1118) IEA Gallus gallus A0A1D5PK20 R-GGA-9843120 https://reactome.org/PathwayBrowser/#/R-GGA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1D5PK40 R-GGA-5669012 https://reactome.org/PathwayBrowser/#/R-GGA-5669012 EDA binds EDAR IEA Gallus gallus A0A1D5PK40 R-GGA-5669013 https://reactome.org/PathwayBrowser/#/R-GGA-5669013 EDA-3 binds EDA2R IEA Gallus gallus A0A1D5PK40 R-GGA-5675656 https://reactome.org/PathwayBrowser/#/R-GGA-5675656 EDA:EDAR binds EDARADD IEA Gallus gallus A0A1D5PK41 R-GGA-201611 https://reactome.org/PathwayBrowser/#/R-GGA-201611 Caspase-mediated cleavage of Rock-1 IEA Gallus gallus A0A1D5PK41 R-GGA-3928576 https://reactome.org/PathwayBrowser/#/R-GGA-3928576 RHOA:GTP binds ROCK, activating it IEA Gallus gallus A0A1D5PK41 R-GGA-3928647 https://reactome.org/PathwayBrowser/#/R-GGA-3928647 RHOA:GTP:Mg2+ binds ROCK1,ROCK2 IEA Gallus gallus A0A1D5PK41 R-GGA-419049 https://reactome.org/PathwayBrowser/#/R-GGA-419049 ROCK activation by RHO IEA Gallus gallus A0A1D5PK41 R-GGA-5218826 https://reactome.org/PathwayBrowser/#/R-GGA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Gallus gallus A0A1D5PK41 R-GGA-5228992 https://reactome.org/PathwayBrowser/#/R-GGA-5228992 ROCK1,ROCK2 are activated IEA Gallus gallus A0A1D5PK41 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PK41 R-GGA-9013009 https://reactome.org/PathwayBrowser/#/R-GGA-9013009 RHOA binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PK41 R-GGA-9013024 https://reactome.org/PathwayBrowser/#/R-GGA-9013024 RHOB binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PK41 R-GGA-9013110 https://reactome.org/PathwayBrowser/#/R-GGA-9013110 RHOC binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PK41 R-GGA-9018758 https://reactome.org/PathwayBrowser/#/R-GGA-9018758 RHOH binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PK41 R-GGA-9018778 https://reactome.org/PathwayBrowser/#/R-GGA-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Gallus gallus A0A1D5PK41 R-GGA-9680443 https://reactome.org/PathwayBrowser/#/R-GGA-9680443 ROCK1,2 bind ROCKi IEA Gallus gallus A0A1D5PK41 R-GGA-9696268 https://reactome.org/PathwayBrowser/#/R-GGA-9696268 RND3 binds effectors IEA Gallus gallus A0A1D5PK45 R-GGA-5696605 https://reactome.org/PathwayBrowser/#/R-GGA-5696605 USP12, USP26 deubiquitinate AR IEA Gallus gallus A0A1D5PK47 R-GGA-8864278 https://reactome.org/PathwayBrowser/#/R-GGA-8864278 AP-2 (TFAP2) transcription factors form homo- and heterodimers IEA Gallus gallus A0A1D5PK47 R-GGA-8864307 https://reactome.org/PathwayBrowser/#/R-GGA-8864307 TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP IEA Gallus gallus A0A1D5PK47 R-GGA-8864343 https://reactome.org/PathwayBrowser/#/R-GGA-8864343 KCTD1 binds TFAP2 homo- and heterodimers IEA Gallus gallus A0A1D5PK56 R-GGA-9647982 https://reactome.org/PathwayBrowser/#/R-GGA-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Gallus gallus A0A1D5PK72 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus A0A1D5PK82 R-GGA-1067651 https://reactome.org/PathwayBrowser/#/R-GGA-1067651 IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) IEA Gallus gallus A0A1D5PK82 R-GGA-1067659 https://reactome.org/PathwayBrowser/#/R-GGA-1067659 Assembly of hexameric IL-6 receptor IEA Gallus gallus A0A1D5PK82 R-GGA-1067688 https://reactome.org/PathwayBrowser/#/R-GGA-1067688 IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) IEA Gallus gallus A0A1D5PK82 R-GGA-1112510 https://reactome.org/PathwayBrowser/#/R-GGA-1112510 IL6ST is tyrosine phosphorylated IEA Gallus gallus A0A1D5PK82 R-GGA-1112514 https://reactome.org/PathwayBrowser/#/R-GGA-1112514 JAK activation IEA Gallus gallus A0A1D5PK82 R-GGA-1112565 https://reactome.org/PathwayBrowser/#/R-GGA-1112565 Tyrosine phosphorylated IL6ST binds STAT1,STAT3 IEA Gallus gallus A0A1D5PK82 R-GGA-1112602 https://reactome.org/PathwayBrowser/#/R-GGA-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Gallus gallus A0A1D5PK82 R-GGA-1112604 https://reactome.org/PathwayBrowser/#/R-GGA-1112604 Phosphorylated STATs are released IEA Gallus gallus A0A1D5PK82 R-GGA-1112690 https://reactome.org/PathwayBrowser/#/R-GGA-1112690 PTPN11 binds CBL IEA Gallus gallus A0A1D5PK82 R-GGA-1112703 https://reactome.org/PathwayBrowser/#/R-GGA-1112703 PTPN11 is phosphorylated IEA Gallus gallus A0A1D5PK82 R-GGA-1112708 https://reactome.org/PathwayBrowser/#/R-GGA-1112708 PTPN11 binds p-Y759-IL6ST IEA Gallus gallus A0A1D5PK82 R-GGA-1112727 https://reactome.org/PathwayBrowser/#/R-GGA-1112727 Serine phosphorylation of STATs IEA Gallus gallus A0A1D5PK82 R-GGA-1112755 https://reactome.org/PathwayBrowser/#/R-GGA-1112755 SOCS3 binds IL6ST IEA Gallus gallus A0A1D5PK82 R-GGA-447226 https://reactome.org/PathwayBrowser/#/R-GGA-447226 Interleukin-12 binds Interleukin-12 receptor IEA Gallus gallus A0A1D5PK82 R-GGA-447252 https://reactome.org/PathwayBrowser/#/R-GGA-447252 IL12RB1:TYK2 binds IL12RB2:JAK2 IEA Gallus gallus A0A1D5PK82 R-GGA-448661 https://reactome.org/PathwayBrowser/#/R-GGA-448661 IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 IEA Gallus gallus A0A1D5PK82 R-GGA-449811 https://reactome.org/PathwayBrowser/#/R-GGA-449811 IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 IEA Gallus gallus A0A1D5PK82 R-GGA-449976 https://reactome.org/PathwayBrowser/#/R-GGA-449976 IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) IEA Gallus gallus A0A1D5PK82 R-GGA-6783556 https://reactome.org/PathwayBrowser/#/R-GGA-6783556 LIFR:JAKs bind gp130:JAKs:CNTFR IEA Gallus gallus A0A1D5PK82 R-GGA-6784006 https://reactome.org/PathwayBrowser/#/R-GGA-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Gallus gallus A0A1D5PK82 R-GGA-6784189 https://reactome.org/PathwayBrowser/#/R-GGA-6784189 JAKs bind LIFR IEA Gallus gallus A0A1D5PK82 R-GGA-6784319 https://reactome.org/PathwayBrowser/#/R-GGA-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Gallus gallus A0A1D5PK82 R-GGA-6784323 https://reactome.org/PathwayBrowser/#/R-GGA-6784323 IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 IEA Gallus gallus A0A1D5PK82 R-GGA-6784324 https://reactome.org/PathwayBrowser/#/R-GGA-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Gallus gallus A0A1D5PK82 R-GGA-6784791 https://reactome.org/PathwayBrowser/#/R-GGA-6784791 p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 IEA Gallus gallus A0A1D5PK82 R-GGA-6785762 https://reactome.org/PathwayBrowser/#/R-GGA-6785762 IL13RA1 binds TYK2 IEA Gallus gallus A0A1D5PK82 R-GGA-6785821 https://reactome.org/PathwayBrowser/#/R-GGA-6785821 SOCS5,(SOCS1) bind IL4RA IEA Gallus gallus A0A1D5PK82 R-GGA-6786050 https://reactome.org/PathwayBrowser/#/R-GGA-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated IEA Gallus gallus A0A1D5PK82 R-GGA-6786070 https://reactome.org/PathwayBrowser/#/R-GGA-6786070 IL4:IL4R:JAK2 binds IL13RA1:TYK2 IEA Gallus gallus A0A1D5PK82 R-GGA-6786110 https://reactome.org/PathwayBrowser/#/R-GGA-6786110 JAK1 binds IL4R in IL13-bound IL13R type II IEA Gallus gallus A0A1D5PK82 R-GGA-6788571 https://reactome.org/PathwayBrowser/#/R-GGA-6788571 STAT1,STAT3,STAT6 bind IL13:IL13R type II IEA Gallus gallus A0A1D5PK82 R-GGA-6788582 https://reactome.org/PathwayBrowser/#/R-GGA-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Gallus gallus A0A1D5PK82 R-GGA-6788628 https://reactome.org/PathwayBrowser/#/R-GGA-6788628 p-Y-STATs dissociate IEA Gallus gallus A0A1D5PK82 R-GGA-8854645 https://reactome.org/PathwayBrowser/#/R-GGA-8854645 IL22:IL22RA1:JAK1 binds IL10RB:TYK2 IEA Gallus gallus A0A1D5PK82 R-GGA-8950128 https://reactome.org/PathwayBrowser/#/R-GGA-8950128 Interleukin-12 dissociates from Interleukin-12 receptor IEA Gallus gallus A0A1D5PK82 R-GGA-8950269 https://reactome.org/PathwayBrowser/#/R-GGA-8950269 STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor IEA Gallus gallus A0A1D5PK82 R-GGA-8950405 https://reactome.org/PathwayBrowser/#/R-GGA-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated IEA Gallus gallus A0A1D5PK82 R-GGA-8950423 https://reactome.org/PathwayBrowser/#/R-GGA-8950423 JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated IEA Gallus gallus A0A1D5PK82 R-GGA-8950448 https://reactome.org/PathwayBrowser/#/R-GGA-8950448 STAT4 binds to IL12RB2 in Interleukin-12 receptor complex IEA Gallus gallus A0A1D5PK82 R-GGA-8950757 https://reactome.org/PathwayBrowser/#/R-GGA-8950757 IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated IEA Gallus gallus A0A1D5PK82 R-GGA-8952749 https://reactome.org/PathwayBrowser/#/R-GGA-8952749 STAT4 binds p-Y-IL23R in IL23:IL23 receptor IEA Gallus gallus A0A1D5PK82 R-GGA-8952807 https://reactome.org/PathwayBrowser/#/R-GGA-8952807 p-Y693-STAT4 dissociates after IL12:IL12R interaction IEA Gallus gallus A0A1D5PK82 R-GGA-8952823 https://reactome.org/PathwayBrowser/#/R-GGA-8952823 p-Y693-STAT4, p-Y705-STAT3 dissociate from IL23:IL23 receptor IEA Gallus gallus A0A1D5PK82 R-GGA-8981093 https://reactome.org/PathwayBrowser/#/R-GGA-8981093 IL12 bound to IL12R internalises IEA Gallus gallus A0A1D5PK82 R-GGA-8983834 https://reactome.org/PathwayBrowser/#/R-GGA-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated IEA Gallus gallus A0A1D5PK82 R-GGA-8986480 https://reactome.org/PathwayBrowser/#/R-GGA-8986480 IL26:IL20RA:JAK1 binds IL10RB:TYK2 IEA Gallus gallus A0A1D5PK82 R-GGA-8986985 https://reactome.org/PathwayBrowser/#/R-GGA-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Gallus gallus A0A1D5PK82 R-GGA-8986994 https://reactome.org/PathwayBrowser/#/R-GGA-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Gallus gallus A0A1D5PK82 R-GGA-8986995 https://reactome.org/PathwayBrowser/#/R-GGA-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Gallus gallus A0A1D5PK82 R-GGA-8987014 https://reactome.org/PathwayBrowser/#/R-GGA-8987014 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 IEA Gallus gallus A0A1D5PK82 R-GGA-8987033 https://reactome.org/PathwayBrowser/#/R-GGA-8987033 p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 IEA Gallus gallus A0A1D5PK82 R-GGA-8987040 https://reactome.org/PathwayBrowser/#/R-GGA-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Gallus gallus A0A1D5PK82 R-GGA-8987042 https://reactome.org/PathwayBrowser/#/R-GGA-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Gallus gallus A0A1D5PK82 R-GGA-8987070 https://reactome.org/PathwayBrowser/#/R-GGA-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Gallus gallus A0A1D5PK82 R-GGA-8987080 https://reactome.org/PathwayBrowser/#/R-GGA-8987080 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 IEA Gallus gallus A0A1D5PK82 R-GGA-8987105 https://reactome.org/PathwayBrowser/#/R-GGA-8987105 IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 IEA Gallus gallus A0A1D5PK82 R-GGA-8987132 https://reactome.org/PathwayBrowser/#/R-GGA-8987132 IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11 IEA Gallus gallus A0A1D5PK82 R-GGA-8987202 https://reactome.org/PathwayBrowser/#/R-GGA-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Gallus gallus A0A1D5PK82 R-GGA-8987223 https://reactome.org/PathwayBrowser/#/R-GGA-8987223 IL10RB binds TYK2 IEA Gallus gallus A0A1D5PK82 R-GGA-8987230 https://reactome.org/PathwayBrowser/#/R-GGA-8987230 p-STAT1 and p-STAT3 dissociates from IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 IEA Gallus gallus A0A1D5PK82 R-GGA-8987236 https://reactome.org/PathwayBrowser/#/R-GGA-8987236 p-Y705-STAT3 dissociates from IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 IEA Gallus gallus A0A1D5PK82 R-GGA-8987255 https://reactome.org/PathwayBrowser/#/R-GGA-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Gallus gallus A0A1D5PK82 R-GGA-8987266 https://reactome.org/PathwayBrowser/#/R-GGA-8987266 IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 IEA Gallus gallus A0A1D5PK82 R-GGA-909718 https://reactome.org/PathwayBrowser/#/R-GGA-909718 Formation of p-STAT1 homodimer IEA Gallus gallus A0A1D5PK82 R-GGA-909719 https://reactome.org/PathwayBrowser/#/R-GGA-909719 Recruitment of STAT2 to p-IFNAR1 IEA Gallus gallus A0A1D5PK82 R-GGA-909722 https://reactome.org/PathwayBrowser/#/R-GGA-909722 Release of p-STAT2:p-STAT1 dimer IEA Gallus gallus A0A1D5PK82 R-GGA-909724 https://reactome.org/PathwayBrowser/#/R-GGA-909724 Recruitment of IFNAR1 IEA Gallus gallus A0A1D5PK82 R-GGA-909729 https://reactome.org/PathwayBrowser/#/R-GGA-909729 Activation of JAK kinases IEA Gallus gallus A0A1D5PK82 R-GGA-909730 https://reactome.org/PathwayBrowser/#/R-GGA-909730 Phosphorylation of INFAR1 by TYK2 IEA Gallus gallus A0A1D5PK82 R-GGA-909732 https://reactome.org/PathwayBrowser/#/R-GGA-909732 Phosphorylation of STAT2 IEA Gallus gallus A0A1D5PK82 R-GGA-9674816 https://reactome.org/PathwayBrowser/#/R-GGA-9674816 p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS IEA Gallus gallus A0A1D5PK82 R-GGA-9678737 https://reactome.org/PathwayBrowser/#/R-GGA-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Gallus gallus A0A1D5PK82 R-GGA-9707977 https://reactome.org/PathwayBrowser/#/R-GGA-9707977 CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane IEA Gallus gallus A0A1D5PK82 R-GGA-997309 https://reactome.org/PathwayBrowser/#/R-GGA-997309 Dephosphorylation of STAT1 by SHP2 IEA Gallus gallus A0A1D5PK82 R-GGA-997311 https://reactome.org/PathwayBrowser/#/R-GGA-997311 Dephosphorylation of TYK2 by PTP1B IEA Gallus gallus A0A1D5PK82 R-GGA-997314 https://reactome.org/PathwayBrowser/#/R-GGA-997314 Dephosphorylation of JAK1 by SHP1 IEA Gallus gallus A0A1D5PK99 R-GGA-212380 https://reactome.org/PathwayBrowser/#/R-GGA-212380 Formation of TRAP coactivator complex IEA Gallus gallus A0A1D5PK99 R-GGA-9843120 https://reactome.org/PathwayBrowser/#/R-GGA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1D5PKA3 R-GGA-880007 https://reactome.org/PathwayBrowser/#/R-GGA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Gallus gallus A0A1D5PKB0 R-GGA-5631903 https://reactome.org/PathwayBrowser/#/R-GGA-5631903 SESN1,2,3 bind overoxidized PRDX1 IEA Gallus gallus A0A1D5PKB0 R-GGA-5631941 https://reactome.org/PathwayBrowser/#/R-GGA-5631941 SESN1,2,3 bind AMPK IEA Gallus gallus A0A1D5PKB0 R-GGA-9639287 https://reactome.org/PathwayBrowser/#/R-GGA-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Gallus gallus A0A1D5PKB0 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus A0A1D5PKB0 R-GGA-9766645 https://reactome.org/PathwayBrowser/#/R-GGA-9766645 CUL3:RBX1 ubiquitinates KEAP1 IEA Gallus gallus A0A1D5PKB0 R-GGA-9766656 https://reactome.org/PathwayBrowser/#/R-GGA-9766656 RBX1:CUL3 dissociates from forming autophagosome IEA Gallus gallus A0A1D5PKB0 R-GGA-9766677 https://reactome.org/PathwayBrowser/#/R-GGA-9766677 MAP1LC3B binds KEAP1 and SQSTM1 IEA Gallus gallus A0A1D5PKB0 R-GGA-9766687 https://reactome.org/PathwayBrowser/#/R-GGA-9766687 SESN1,SESN1 bind SQSTM1 and KEAP1 IEA Gallus gallus A0A1D5PKB5 R-GGA-6785821 https://reactome.org/PathwayBrowser/#/R-GGA-6785821 SOCS5,(SOCS1) bind IL4RA IEA Gallus gallus A0A1D5PKB5 R-GGA-6785898 https://reactome.org/PathwayBrowser/#/R-GGA-6785898 IL4R binds JAK2 IEA Gallus gallus A0A1D5PKB5 R-GGA-6786050 https://reactome.org/PathwayBrowser/#/R-GGA-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated IEA Gallus gallus A0A1D5PKB5 R-GGA-6786058 https://reactome.org/PathwayBrowser/#/R-GGA-6786058 JAK1 binds IL4R in IL4-bound IL4R1 IEA Gallus gallus A0A1D5PKB5 R-GGA-6786070 https://reactome.org/PathwayBrowser/#/R-GGA-6786070 IL4:IL4R:JAK2 binds IL13RA1:TYK2 IEA Gallus gallus A0A1D5PKB5 R-GGA-6786072 https://reactome.org/PathwayBrowser/#/R-GGA-6786072 p-Y705-STAT3,p-Y641-STAT6 dissociate IEA Gallus gallus A0A1D5PKB5 R-GGA-6786095 https://reactome.org/PathwayBrowser/#/R-GGA-6786095 JAK1 phosphorylates STAT3,STAT6 IEA Gallus gallus A0A1D5PKB5 R-GGA-6786096 https://reactome.org/PathwayBrowser/#/R-GGA-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated IEA Gallus gallus A0A1D5PKB5 R-GGA-6786101 https://reactome.org/PathwayBrowser/#/R-GGA-6786101 IL4 binds IL4R:JAK2 IEA Gallus gallus A0A1D5PKB5 R-GGA-6786110 https://reactome.org/PathwayBrowser/#/R-GGA-6786110 JAK1 binds IL4R in IL13-bound IL13R type II IEA Gallus gallus A0A1D5PKB5 R-GGA-6786124 https://reactome.org/PathwayBrowser/#/R-GGA-6786124 STAT3,STAT6 bind p-Y-IL4R IEA Gallus gallus A0A1D5PKB5 R-GGA-6788571 https://reactome.org/PathwayBrowser/#/R-GGA-6788571 STAT1,STAT3,STAT6 bind IL13:IL13R type II IEA Gallus gallus A0A1D5PKB5 R-GGA-6788582 https://reactome.org/PathwayBrowser/#/R-GGA-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Gallus gallus A0A1D5PKB5 R-GGA-6788628 https://reactome.org/PathwayBrowser/#/R-GGA-6788628 p-Y-STATs dissociate IEA Gallus gallus A0A1D5PKB8 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PKC2 R-GGA-73635 https://reactome.org/PathwayBrowser/#/R-GGA-73635 dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] IEA Gallus gallus A0A1D5PKC2 R-GGA-75126 https://reactome.org/PathwayBrowser/#/R-GGA-75126 dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] IEA Gallus gallus A0A1D5PKD9 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PKE1 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus A0A1D5PKE1 R-GGA-6788523 https://reactome.org/PathwayBrowser/#/R-GGA-6788523 NUBPL transfers 4Fe-4S to Complex I subunits IEA Gallus gallus A0A1D5PKE1 R-GGA-6799178 https://reactome.org/PathwayBrowser/#/R-GGA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Gallus gallus A0A1D5PKE1 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus A0A1D5PKE1 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus A0A1D5PKE1 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus A0A1D5PKE1 R-GGA-6799202 https://reactome.org/PathwayBrowser/#/R-GGA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Gallus gallus A0A1D5PKE1 R-GGA-6799203 https://reactome.org/PathwayBrowser/#/R-GGA-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Gallus gallus A0A1D5PKE1 R-GGA-6800868 https://reactome.org/PathwayBrowser/#/R-GGA-6800868 NDUF subunits bind to form the IP subcomplex IEA Gallus gallus A0A1D5PKE9 R-GGA-428185 https://reactome.org/PathwayBrowser/#/R-GGA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Gallus gallus A0A1D5PKF4 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PKF4 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PKF4 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PKF4 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PKF7 R-GGA-5686924 https://reactome.org/PathwayBrowser/#/R-GGA-5686924 DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs IEA Gallus gallus A0A1D5PKF7 R-GGA-5687183 https://reactome.org/PathwayBrowser/#/R-GGA-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Gallus gallus A0A1D5PKF7 R-GGA-5687360 https://reactome.org/PathwayBrowser/#/R-GGA-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Gallus gallus A0A1D5PKF7 R-GGA-5693533 https://reactome.org/PathwayBrowser/#/R-GGA-5693533 DCLRE1C (ARTEMIS) processes DNA DSB ends IEA Gallus gallus A0A1D5PKF7 R-GGA-5693574 https://reactome.org/PathwayBrowser/#/R-GGA-5693574 XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ IEA Gallus gallus A0A1D5PKF7 R-GGA-5693575 https://reactome.org/PathwayBrowser/#/R-GGA-5693575 DNA-PKcs autophosphorylates IEA Gallus gallus A0A1D5PKF7 R-GGA-5693578 https://reactome.org/PathwayBrowser/#/R-GGA-5693578 TDP1 and TDP2 process unligatable DSB ends IEA Gallus gallus A0A1D5PKF7 R-GGA-5693615 https://reactome.org/PathwayBrowser/#/R-GGA-5693615 Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis IEA Gallus gallus A0A1D5PKF7 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PKF7 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PKG3 R-GGA-71802 https://reactome.org/PathwayBrowser/#/R-GGA-71802 PFKFKB dimer phosphorylates Fru(6)P IEA Gallus gallus A0A1D5PKG8 R-GGA-8853496 https://reactome.org/PathwayBrowser/#/R-GGA-8853496 SCF:FBXL7 binds AURKA IEA Gallus gallus A0A1D5PKG8 R-GGA-8854041 https://reactome.org/PathwayBrowser/#/R-GGA-8854041 SCF-FBXL7 ubiquitinates AURKA IEA Gallus gallus A0A1D5PKG8 R-GGA-8854044 https://reactome.org/PathwayBrowser/#/R-GGA-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Gallus gallus A0A1D5PKG8 R-GGA-8854051 https://reactome.org/PathwayBrowser/#/R-GGA-8854051 SCF-FBXL18 ubiquitinates FBXL7 IEA Gallus gallus A0A1D5PKG8 R-GGA-8854052 https://reactome.org/PathwayBrowser/#/R-GGA-8854052 Formation of the SCF-FBXL7 complex IEA Gallus gallus A0A1D5PKG8 R-GGA-8854071 https://reactome.org/PathwayBrowser/#/R-GGA-8854071 Proteasome-mediated degradation of PolyUb-FBXL7 IEA Gallus gallus A0A1D5PKG8 R-GGA-8952618 https://reactome.org/PathwayBrowser/#/R-GGA-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PKG8 R-GGA-8952620 https://reactome.org/PathwayBrowser/#/R-GGA-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PKG8 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5PKG8 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5PKG8 R-GGA-8956200 https://reactome.org/PathwayBrowser/#/R-GGA-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PKG8 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PKG8 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PKG8 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PKG8 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PKH0 R-GGA-1250195 https://reactome.org/PathwayBrowser/#/R-GGA-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Gallus gallus A0A1D5PKH0 R-GGA-1306957 https://reactome.org/PathwayBrowser/#/R-GGA-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Gallus gallus A0A1D5PKH0 R-GGA-1306963 https://reactome.org/PathwayBrowser/#/R-GGA-1306963 Binding of GRB2:GAB1 to p-ERBB2:p-EGFR IEA Gallus gallus A0A1D5PKH0 R-GGA-1306965 https://reactome.org/PathwayBrowser/#/R-GGA-1306965 Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Gallus gallus A0A1D5PKH0 R-GGA-177922 https://reactome.org/PathwayBrowser/#/R-GGA-177922 EGFR dimerization IEA Gallus gallus A0A1D5PKH0 R-GGA-177923 https://reactome.org/PathwayBrowser/#/R-GGA-177923 Sustained activation of SRC kinase by SHP2 IEA Gallus gallus A0A1D5PKH0 R-GGA-177924 https://reactome.org/PathwayBrowser/#/R-GGA-177924 Dephosphorylation of Gab1 by SHP2 IEA Gallus gallus A0A1D5PKH0 R-GGA-177925 https://reactome.org/PathwayBrowser/#/R-GGA-177925 SHC1 binds to the phosphorylated EGF receptor:ligand complex IEA Gallus gallus A0A1D5PKH0 R-GGA-177926 https://reactome.org/PathwayBrowser/#/R-GGA-177926 Dephosphorylation of PAG by SHP2 IEA Gallus gallus A0A1D5PKH0 R-GGA-177927 https://reactome.org/PathwayBrowser/#/R-GGA-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 IEA Gallus gallus A0A1D5PKH0 R-GGA-177930 https://reactome.org/PathwayBrowser/#/R-GGA-177930 GAB1 phosphorylation by EGFR kinase IEA Gallus gallus A0A1D5PKH0 R-GGA-177933 https://reactome.org/PathwayBrowser/#/R-GGA-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Gallus gallus A0A1D5PKH0 R-GGA-177934 https://reactome.org/PathwayBrowser/#/R-GGA-177934 EGFR autophosphorylation IEA Gallus gallus A0A1D5PKH0 R-GGA-177935 https://reactome.org/PathwayBrowser/#/R-GGA-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Gallus gallus A0A1D5PKH0 R-GGA-177936 https://reactome.org/PathwayBrowser/#/R-GGA-177936 GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR IEA Gallus gallus A0A1D5PKH0 R-GGA-177937 https://reactome.org/PathwayBrowser/#/R-GGA-177937 Phosphorylation of EGFR by SRC kinase IEA Gallus gallus A0A1D5PKH0 R-GGA-177938 https://reactome.org/PathwayBrowser/#/R-GGA-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Gallus gallus A0A1D5PKH0 R-GGA-177939 https://reactome.org/PathwayBrowser/#/R-GGA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Gallus gallus A0A1D5PKH0 R-GGA-177941 https://reactome.org/PathwayBrowser/#/R-GGA-177941 GRB2:GAB1 binds to phosphorylated EGFR IEA Gallus gallus A0A1D5PKH0 R-GGA-177942 https://reactome.org/PathwayBrowser/#/R-GGA-177942 EGFR binds EGF ligand IEA Gallus gallus A0A1D5PKH0 R-GGA-177943 https://reactome.org/PathwayBrowser/#/R-GGA-177943 GRB2:SOS1 complex binds to EGF:EGFR complex IEA Gallus gallus A0A1D5PKH0 R-GGA-177944 https://reactome.org/PathwayBrowser/#/R-GGA-177944 Activation of SHP2 through the binding to phospho-Gab1 IEA Gallus gallus A0A1D5PKH0 R-GGA-177945 https://reactome.org/PathwayBrowser/#/R-GGA-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Gallus gallus A0A1D5PKH0 R-GGA-182969 https://reactome.org/PathwayBrowser/#/R-GGA-182969 Phosphorylation of CBL (EGFR:CBL) IEA Gallus gallus A0A1D5PKH0 R-GGA-182986 https://reactome.org/PathwayBrowser/#/R-GGA-182986 CBL-mediated ubiquitination of CIN85 IEA Gallus gallus A0A1D5PKH0 R-GGA-182990 https://reactome.org/PathwayBrowser/#/R-GGA-182990 Sprouty sequesters CBL away from active EGFR IEA Gallus gallus A0A1D5PKH0 R-GGA-182993 https://reactome.org/PathwayBrowser/#/R-GGA-182993 Ubiquitination of stimulated EGFR (CBL) IEA Gallus gallus A0A1D5PKH0 R-GGA-182994 https://reactome.org/PathwayBrowser/#/R-GGA-182994 Assembly of EGFR complex in clathrin-coated vesicles IEA Gallus gallus A0A1D5PKH0 R-GGA-183002 https://reactome.org/PathwayBrowser/#/R-GGA-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Gallus gallus A0A1D5PKH0 R-GGA-183036 https://reactome.org/PathwayBrowser/#/R-GGA-183036 Ubiquitination of stimulated EGFR (CBL:GRB2) IEA Gallus gallus A0A1D5PKH0 R-GGA-183051 https://reactome.org/PathwayBrowser/#/R-GGA-183051 CBL ubiquitinates Sprouty IEA Gallus gallus A0A1D5PKH0 R-GGA-183055 https://reactome.org/PathwayBrowser/#/R-GGA-183055 Binding of CBL to EGFR IEA Gallus gallus A0A1D5PKH0 R-GGA-183058 https://reactome.org/PathwayBrowser/#/R-GGA-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Gallus gallus A0A1D5PKH0 R-GGA-183067 https://reactome.org/PathwayBrowser/#/R-GGA-183067 Localization of CBL:GRB2 to the membrane IEA Gallus gallus A0A1D5PKH0 R-GGA-183084 https://reactome.org/PathwayBrowser/#/R-GGA-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Gallus gallus A0A1D5PKH0 R-GGA-183089 https://reactome.org/PathwayBrowser/#/R-GGA-183089 CBL binds and ubiquitinates phosphorylated Sprouty IEA Gallus gallus A0A1D5PKH0 R-GGA-1963563 https://reactome.org/PathwayBrowser/#/R-GGA-1963563 MATK (CSK homologous kinase) binds phosphorylated ERBB2 IEA Gallus gallus A0A1D5PKH0 R-GGA-1963581 https://reactome.org/PathwayBrowser/#/R-GGA-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Gallus gallus A0A1D5PKH0 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus A0A1D5PKH0 R-GGA-1963586 https://reactome.org/PathwayBrowser/#/R-GGA-1963586 SRC family kinases phosphorylate ERBB2 IEA Gallus gallus A0A1D5PKH0 R-GGA-1977959 https://reactome.org/PathwayBrowser/#/R-GGA-1977959 ERBB4 forms heterodimers with EGFR IEA Gallus gallus A0A1D5PKH0 R-GGA-212706 https://reactome.org/PathwayBrowser/#/R-GGA-212706 Phospholipase C-gamma1 binds to the activated EGF receptor IEA Gallus gallus A0A1D5PKH0 R-GGA-212710 https://reactome.org/PathwayBrowser/#/R-GGA-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Gallus gallus A0A1D5PKH0 R-GGA-212713 https://reactome.org/PathwayBrowser/#/R-GGA-212713 Active PLC-gamma1 dissociates from EGFR IEA Gallus gallus A0A1D5PKH0 R-GGA-2179387 https://reactome.org/PathwayBrowser/#/R-GGA-2179387 Mature HBEGF binds to EGFR, triggering dimerisation and autophosphorylation of the receptor IEA Gallus gallus A0A1D5PKH0 R-GGA-2179407 https://reactome.org/PathwayBrowser/#/R-GGA-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Gallus gallus A0A1D5PKH0 R-GGA-2179415 https://reactome.org/PathwayBrowser/#/R-GGA-2179415 GRB2:SOS1 binds to HBEGF:p-Y-EGFR IEA Gallus gallus A0A1D5PKH0 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PKH0 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5PKH0 R-GGA-6785636 https://reactome.org/PathwayBrowser/#/R-GGA-6785636 Phosphorylated ERBB2 heterodimers bind MEMO1 IEA Gallus gallus A0A1D5PKH0 R-GGA-8857549 https://reactome.org/PathwayBrowser/#/R-GGA-8857549 HBEGF-bound EGFR forms a heterodimer with GPNMB IEA Gallus gallus A0A1D5PKH0 R-GGA-8857555 https://reactome.org/PathwayBrowser/#/R-GGA-8857555 EGFR phosphorylates GPNMB IEA Gallus gallus A0A1D5PKH0 R-GGA-8857577 https://reactome.org/PathwayBrowser/#/R-GGA-8857577 LINC01139 facilitates PTK6 autophosphorylation IEA Gallus gallus A0A1D5PKH0 R-GGA-8857583 https://reactome.org/PathwayBrowser/#/R-GGA-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Gallus gallus A0A1D5PKH0 R-GGA-8863804 https://reactome.org/PathwayBrowser/#/R-GGA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Gallus gallus A0A1D5PKH0 R-GGA-8864029 https://reactome.org/PathwayBrowser/#/R-GGA-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Gallus gallus A0A1D5PKH0 R-GGA-8864125 https://reactome.org/PathwayBrowser/#/R-GGA-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Gallus gallus A0A1D5PKH0 R-GGA-8866279 https://reactome.org/PathwayBrowser/#/R-GGA-8866279 Epsin family proteins bind ubiquitinated cargo IEA Gallus gallus A0A1D5PKH0 R-GGA-8867041 https://reactome.org/PathwayBrowser/#/R-GGA-8867041 EGFR phosphorylates EPS15 IEA Gallus gallus A0A1D5PKH0 R-GGA-8867047 https://reactome.org/PathwayBrowser/#/R-GGA-8867047 PTPN3 dephosphorylates EPS15 IEA Gallus gallus A0A1D5PKH0 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5PKH0 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5PKH0 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5PKH0 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5PKH0 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5PKH0 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5PKH0 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5PKH0 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5PKH0 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PKH0 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PKH0 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5PKH0 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5PKH0 R-GGA-8951490 https://reactome.org/PathwayBrowser/#/R-GGA-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Gallus gallus A0A1D5PKH0 R-GGA-9018572 https://reactome.org/PathwayBrowser/#/R-GGA-9018572 EGFR phosphorylates NOTCH3 IEA Gallus gallus A0A1D5PKH0 R-GGA-9018573 https://reactome.org/PathwayBrowser/#/R-GGA-9018573 NOTCH3 binds activated EGFR IEA Gallus gallus A0A1D5PKH0 R-GGA-9625482 https://reactome.org/PathwayBrowser/#/R-GGA-9625482 PTK2 binds activated EGFR IEA Gallus gallus A0A1D5PKH0 R-GGA-9625487 https://reactome.org/PathwayBrowser/#/R-GGA-9625487 PTK2 autophosphorylates downstream of EGFR IEA Gallus gallus A0A1D5PKH0 R-GGA-9634702 https://reactome.org/PathwayBrowser/#/R-GGA-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Gallus gallus A0A1D5PKH0 R-GGA-9674531 https://reactome.org/PathwayBrowser/#/R-GGA-9674531 AAMP binds EGFR IEA Gallus gallus A0A1D5PKH0 R-GGA-9851407 https://reactome.org/PathwayBrowser/#/R-GGA-9851407 FAM83B, (FAM83A, FAM83D) bind EGFR IEA Gallus gallus A0A1D5PKI8 R-GGA-1667005 https://reactome.org/PathwayBrowser/#/R-GGA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Gallus gallus A0A1D5PKI8 R-GGA-1678694 https://reactome.org/PathwayBrowser/#/R-GGA-1678694 Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans IEA Gallus gallus A0A1D5PKI8 R-GGA-1878002 https://reactome.org/PathwayBrowser/#/R-GGA-1878002 XYLTs transfer Xyl to core protein IEA Gallus gallus A0A1D5PKI8 R-GGA-1889955 https://reactome.org/PathwayBrowser/#/R-GGA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Gallus gallus A0A1D5PKI8 R-GGA-1889981 https://reactome.org/PathwayBrowser/#/R-GGA-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Gallus gallus A0A1D5PKI8 R-GGA-2022860 https://reactome.org/PathwayBrowser/#/R-GGA-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Gallus gallus A0A1D5PKI8 R-GGA-2022887 https://reactome.org/PathwayBrowser/#/R-GGA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Gallus gallus A0A1D5PKI8 R-GGA-2024084 https://reactome.org/PathwayBrowser/#/R-GGA-2024084 HS-GAGs translocate to the lysosome for degradation IEA Gallus gallus A0A1D5PKI8 R-GGA-2024108 https://reactome.org/PathwayBrowser/#/R-GGA-2024108 Some HSPGs are secreted to the plasma membrane IEA Gallus gallus A0A1D5PKI8 R-GGA-2076383 https://reactome.org/PathwayBrowser/#/R-GGA-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Gallus gallus A0A1D5PKI8 R-GGA-2076419 https://reactome.org/PathwayBrowser/#/R-GGA-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Gallus gallus A0A1D5PKI8 R-GGA-2076508 https://reactome.org/PathwayBrowser/#/R-GGA-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Gallus gallus A0A1D5PKI8 R-GGA-2076611 https://reactome.org/PathwayBrowser/#/R-GGA-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Gallus gallus A0A1D5PKJ6 R-GGA-389639 https://reactome.org/PathwayBrowser/#/R-GGA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Gallus gallus A0A1D5PKJ6 R-GGA-9033232 https://reactome.org/PathwayBrowser/#/R-GGA-9033232 PEX7 binds cargo proteins containing PTS2 IEA Gallus gallus A0A1D5PKJ6 R-GGA-9033514 https://reactome.org/PathwayBrowser/#/R-GGA-9033514 Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1D5PKK3 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5PKK3 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5PKK3 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5PKK3 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5PKK3 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5PKL6 R-GGA-418442 https://reactome.org/PathwayBrowser/#/R-GGA-418442 PKG1 phosphorylates IRAG:IP3R1 inhibiting IP3-stimulated Ca2+ release IEA Gallus gallus A0A1D5PKL6 R-GGA-913996 https://reactome.org/PathwayBrowser/#/R-GGA-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Gallus gallus A0A1D5PKL9 R-GGA-202706 https://reactome.org/PathwayBrowser/#/R-GGA-202706 Integrin alpha4beta1 binds JAM2:JAM3 IEA Gallus gallus A0A1D5PKL9 R-GGA-216050 https://reactome.org/PathwayBrowser/#/R-GGA-216050 Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix IEA Gallus gallus A0A1D5PKL9 R-GGA-265429 https://reactome.org/PathwayBrowser/#/R-GGA-265429 THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1 IEA Gallus gallus A0A1D5PKL9 R-GGA-9679740 https://reactome.org/PathwayBrowser/#/R-GGA-9679740 ITGA4:ITGB1 binds natalizumab IEA Gallus gallus A0A1D5PKM9 R-GGA-390593 https://reactome.org/PathwayBrowser/#/R-GGA-390593 ATP Hydrolysis By Myosin IEA Gallus gallus A0A1D5PKM9 R-GGA-390595 https://reactome.org/PathwayBrowser/#/R-GGA-390595 Calcium Binds Troponin-C IEA Gallus gallus A0A1D5PKM9 R-GGA-390597 https://reactome.org/PathwayBrowser/#/R-GGA-390597 Release Of ADP From Myosin IEA Gallus gallus A0A1D5PKM9 R-GGA-390598 https://reactome.org/PathwayBrowser/#/R-GGA-390598 Myosin Binds ATP IEA Gallus gallus A0A1D5PKN5 R-GGA-8853429 https://reactome.org/PathwayBrowser/#/R-GGA-8853429 PHLDA1 binds AURKA IEA Gallus gallus A0A1D5PKN5 R-GGA-8853444 https://reactome.org/PathwayBrowser/#/R-GGA-8853444 AURKA phosphorylates PHLDA1 IEA Gallus gallus A0A1D5PKN8 R-GGA-9012721 https://reactome.org/PathwayBrowser/#/R-GGA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Gallus gallus A0A1D5PKN8 R-GGA-9013471 https://reactome.org/PathwayBrowser/#/R-GGA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Gallus gallus A0A1D5PKN8 R-GGA-9013533 https://reactome.org/PathwayBrowser/#/R-GGA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Gallus gallus A0A1D5PKN8 R-GGA-9034756 https://reactome.org/PathwayBrowser/#/R-GGA-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Gallus gallus A0A1D5PKN8 R-GGA-9035484 https://reactome.org/PathwayBrowser/#/R-GGA-9035484 MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST IEA Gallus gallus A0A1D5PKP1 R-GGA-419001 https://reactome.org/PathwayBrowser/#/R-GGA-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Gallus gallus A0A1D5PKP1 R-GGA-419002 https://reactome.org/PathwayBrowser/#/R-GGA-419002 Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin IEA Gallus gallus A0A1D5PKP2 R-GGA-170825 https://reactome.org/PathwayBrowser/#/R-GGA-170825 NPC exports GCK1 from nucleus IEA Gallus gallus A0A1D5PKP2 R-GGA-70420 https://reactome.org/PathwayBrowser/#/R-GGA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Gallus gallus A0A1D5PKP5 R-GGA-8932275 https://reactome.org/PathwayBrowser/#/R-GGA-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Gallus gallus A0A1D5PKP8 R-GGA-1295540 https://reactome.org/PathwayBrowser/#/R-GGA-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 IEA Gallus gallus A0A1D5PKP8 R-GGA-453104 https://reactome.org/PathwayBrowser/#/R-GGA-453104 Phosphorylated SHC1 recruits GRB2:GAB2 IEA Gallus gallus A0A1D5PKP8 R-GGA-508247 https://reactome.org/PathwayBrowser/#/R-GGA-508247 Gab2 binds the p85 subunit of Class 1A PI3 kinases IEA Gallus gallus A0A1D5PKP8 R-GGA-6785165 https://reactome.org/PathwayBrowser/#/R-GGA-6785165 p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B IEA Gallus gallus A0A1D5PKP8 R-GGA-6786058 https://reactome.org/PathwayBrowser/#/R-GGA-6786058 JAK1 binds IL4R in IL4-bound IL4R1 IEA Gallus gallus A0A1D5PKP8 R-GGA-6786072 https://reactome.org/PathwayBrowser/#/R-GGA-6786072 p-Y705-STAT3,p-Y641-STAT6 dissociate IEA Gallus gallus A0A1D5PKP8 R-GGA-6786095 https://reactome.org/PathwayBrowser/#/R-GGA-6786095 JAK1 phosphorylates STAT3,STAT6 IEA Gallus gallus A0A1D5PKP8 R-GGA-6786096 https://reactome.org/PathwayBrowser/#/R-GGA-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated IEA Gallus gallus A0A1D5PKP8 R-GGA-6786124 https://reactome.org/PathwayBrowser/#/R-GGA-6786124 STAT3,STAT6 bind p-Y-IL4R IEA Gallus gallus A0A1D5PKP8 R-GGA-8983003 https://reactome.org/PathwayBrowser/#/R-GGA-8983003 IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 IEA Gallus gallus A0A1D5PKP8 R-GGA-8983059 https://reactome.org/PathwayBrowser/#/R-GGA-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex IEA Gallus gallus A0A1D5PKP8 R-GGA-8983063 https://reactome.org/PathwayBrowser/#/R-GGA-8983063 JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated IEA Gallus gallus A0A1D5PKP8 R-GGA-8983384 https://reactome.org/PathwayBrowser/#/R-GGA-8983384 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 IEA Gallus gallus A0A1D5PKP8 R-GGA-8985900 https://reactome.org/PathwayBrowser/#/R-GGA-8985900 p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 IEA Gallus gallus A0A1D5PKP8 R-GGA-8985914 https://reactome.org/PathwayBrowser/#/R-GGA-8985914 IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 IEA Gallus gallus A0A1D5PKP8 R-GGA-8985929 https://reactome.org/PathwayBrowser/#/R-GGA-8985929 IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B IEA Gallus gallus A0A1D5PKP8 R-GGA-8985973 https://reactome.org/PathwayBrowser/#/R-GGA-8985973 IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 IEA Gallus gallus A0A1D5PKP8 R-GGA-8985988 https://reactome.org/PathwayBrowser/#/R-GGA-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Gallus gallus A0A1D5PKP8 R-GGA-9006850 https://reactome.org/PathwayBrowser/#/R-GGA-9006850 IL21 receptor JAK phosphorylation IEA Gallus gallus A0A1D5PKP8 R-GGA-9006870 https://reactome.org/PathwayBrowser/#/R-GGA-9006870 IL21 receptor STAT phosphorylation IEA Gallus gallus A0A1D5PKP8 R-GGA-9006873 https://reactome.org/PathwayBrowser/#/R-GGA-9006873 IL21 receptor STAT binding IEA Gallus gallus A0A1D5PKP8 R-GGA-9025969 https://reactome.org/PathwayBrowser/#/R-GGA-9025969 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 binds STAT5 IEA Gallus gallus A0A1D5PKP8 R-GGA-912527 https://reactome.org/PathwayBrowser/#/R-GGA-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Gallus gallus A0A1D5PKQ8 R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus A0A1D5PKQ8 R-GGA-211910 https://reactome.org/PathwayBrowser/#/R-GGA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Gallus gallus A0A1D5PKQ8 R-GGA-211929 https://reactome.org/PathwayBrowser/#/R-GGA-211929 CYP2C19 5-hydroxylates omeprazole IEA Gallus gallus A0A1D5PKQ8 R-GGA-211966 https://reactome.org/PathwayBrowser/#/R-GGA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Gallus gallus A0A1D5PKQ8 R-GGA-211988 https://reactome.org/PathwayBrowser/#/R-GGA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Gallus gallus A0A1D5PKQ8 R-GGA-211991 https://reactome.org/PathwayBrowser/#/R-GGA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Gallus gallus A0A1D5PKQ8 R-GGA-76354 https://reactome.org/PathwayBrowser/#/R-GGA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Gallus gallus A0A1D5PKQ8 R-GGA-76397 https://reactome.org/PathwayBrowser/#/R-GGA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Gallus gallus A0A1D5PKQ8 R-GGA-76416 https://reactome.org/PathwayBrowser/#/R-GGA-76416 Benzene is hydroxylated to phenol IEA Gallus gallus A0A1D5PKQ8 R-GGA-76434 https://reactome.org/PathwayBrowser/#/R-GGA-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Gallus gallus A0A1D5PKQ8 R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus A0A1D5PKQ8 R-GGA-76475 https://reactome.org/PathwayBrowser/#/R-GGA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Gallus gallus A0A1D5PKQ8 R-GGA-9027043 https://reactome.org/PathwayBrowser/#/R-GGA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Gallus gallus A0A1D5PKQ8 R-GGA-9027302 https://reactome.org/PathwayBrowser/#/R-GGA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Gallus gallus A0A1D5PKQ8 R-GGA-9027321 https://reactome.org/PathwayBrowser/#/R-GGA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Gallus gallus A0A1D5PKQ8 R-GGA-9749986 https://reactome.org/PathwayBrowser/#/R-GGA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Gallus gallus A0A1D5PKQ8 R-GGA-9750016 https://reactome.org/PathwayBrowser/#/R-GGA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Gallus gallus A0A1D5PKQ8 R-GGA-9753285 https://reactome.org/PathwayBrowser/#/R-GGA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Gallus gallus A0A1D5PKR0 R-GGA-446364 https://reactome.org/PathwayBrowser/#/R-GGA-446364 Migfilin interacts with VASP IEA Gallus gallus A0A1D5PKR5 R-GGA-8956458 https://reactome.org/PathwayBrowser/#/R-GGA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Gallus gallus A0A1D5PKS1 R-GGA-399711 https://reactome.org/PathwayBrowser/#/R-GGA-399711 Activation of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5PKS1 R-GGA-399712 https://reactome.org/PathwayBrowser/#/R-GGA-399712 Activation of Ca permeable AMPA receptors IEA Gallus gallus A0A1D5PKS1 R-GGA-416639 https://reactome.org/PathwayBrowser/#/R-GGA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Gallus gallus A0A1D5PKS1 R-GGA-416985 https://reactome.org/PathwayBrowser/#/R-GGA-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Gallus gallus A0A1D5PKS1 R-GGA-420975 https://reactome.org/PathwayBrowser/#/R-GGA-420975 Ca impermeable AMPA receptor ligand binding IEA Gallus gallus A0A1D5PKS1 R-GGA-420977 https://reactome.org/PathwayBrowser/#/R-GGA-420977 Ca permeable AMPA receptor ligand binding IEA Gallus gallus A0A1D5PKS1 R-GGA-420980 https://reactome.org/PathwayBrowser/#/R-GGA-420980 Activation of Ca permeable AMPA receptors IEA Gallus gallus A0A1D5PKS1 R-GGA-421007 https://reactome.org/PathwayBrowser/#/R-GGA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5PKS1 R-GGA-438037 https://reactome.org/PathwayBrowser/#/R-GGA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5PKS1 R-GGA-8849881 https://reactome.org/PathwayBrowser/#/R-GGA-8849881 SALM2 associate with AMPA and NMDA receptors IEA Gallus gallus A0A1D5PKT3 R-GGA-5205649 https://reactome.org/PathwayBrowser/#/R-GGA-5205649 p62 links damaged mitochondria to LC3 IEA Gallus gallus A0A1D5PKT3 R-GGA-5205663 https://reactome.org/PathwayBrowser/#/R-GGA-5205663 LC3 binds the autophagosome membrane Atg5-Atg12 complex IEA Gallus gallus A0A1D5PKT3 R-GGA-5205673 https://reactome.org/PathwayBrowser/#/R-GGA-5205673 p62 binds ubiquitinated mitochondrial substrates IEA Gallus gallus A0A1D5PKT3 R-GGA-5696872 https://reactome.org/PathwayBrowser/#/R-GGA-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Gallus gallus A0A1D5PKT3 R-GGA-9824888 https://reactome.org/PathwayBrowser/#/R-GGA-9824888 OPTN, TBK1 bind ubiquitinated MOM proteins IEA Gallus gallus A0A1D5PKT3 R-GGA-9824892 https://reactome.org/PathwayBrowser/#/R-GGA-9824892 MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria IEA Gallus gallus A0A1D5PKT3 R-GGA-9824894 https://reactome.org/PathwayBrowser/#/R-GGA-9824894 TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins IEA Gallus gallus A0A1D5PKT3 R-GGA-9824897 https://reactome.org/PathwayBrowser/#/R-GGA-9824897 p-S-TBK1 phosphorylates OPTN IEA Gallus gallus A0A1D5PKT3 R-GGA-9835009 https://reactome.org/PathwayBrowser/#/R-GGA-9835009 PRKN binds p-S-Ub:MOM proteins IEA Gallus gallus A0A1D5PKT3 R-GGA-9840807 https://reactome.org/PathwayBrowser/#/R-GGA-9840807 OPTN binds ATG9A IEA Gallus gallus A0A1D5PKT5 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PKV6 R-GGA-5662466 https://reactome.org/PathwayBrowser/#/R-GGA-5662466 XYLB phosphorylates D-xylulose IEA Gallus gallus A0A1D5PKW3 R-GGA-8952630 https://reactome.org/PathwayBrowser/#/R-GGA-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PKW3 R-GGA-8952631 https://reactome.org/PathwayBrowser/#/R-GGA-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PKW3 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5PKW3 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5PKW3 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PKW3 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PKW3 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PKW3 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PKW8 R-GGA-75079 https://reactome.org/PathwayBrowser/#/R-GGA-75079 Formation of AT-AC C complex IEA Gallus gallus A0A1D5PKW8 R-GGA-75081 https://reactome.org/PathwayBrowser/#/R-GGA-75081 Formation of AT-AC B Complex IEA Gallus gallus A0A1D5PKW8 R-GGA-75082 https://reactome.org/PathwayBrowser/#/R-GGA-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Gallus gallus A0A1D5PKW8 R-GGA-75083 https://reactome.org/PathwayBrowser/#/R-GGA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Gallus gallus A0A1D5PKY5 R-GGA-399711 https://reactome.org/PathwayBrowser/#/R-GGA-399711 Activation of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5PKY5 R-GGA-399712 https://reactome.org/PathwayBrowser/#/R-GGA-399712 Activation of Ca permeable AMPA receptors IEA Gallus gallus A0A1D5PKY5 R-GGA-416639 https://reactome.org/PathwayBrowser/#/R-GGA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Gallus gallus A0A1D5PKY5 R-GGA-416985 https://reactome.org/PathwayBrowser/#/R-GGA-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Gallus gallus A0A1D5PKY5 R-GGA-420975 https://reactome.org/PathwayBrowser/#/R-GGA-420975 Ca impermeable AMPA receptor ligand binding IEA Gallus gallus A0A1D5PKY5 R-GGA-420977 https://reactome.org/PathwayBrowser/#/R-GGA-420977 Ca permeable AMPA receptor ligand binding IEA Gallus gallus A0A1D5PKY5 R-GGA-420980 https://reactome.org/PathwayBrowser/#/R-GGA-420980 Activation of Ca permeable AMPA receptors IEA Gallus gallus A0A1D5PKY5 R-GGA-421007 https://reactome.org/PathwayBrowser/#/R-GGA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5PKY5 R-GGA-438037 https://reactome.org/PathwayBrowser/#/R-GGA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5PKY5 R-GGA-8849881 https://reactome.org/PathwayBrowser/#/R-GGA-8849881 SALM2 associate with AMPA and NMDA receptors IEA Gallus gallus A0A1D5PKY6 R-GGA-212380 https://reactome.org/PathwayBrowser/#/R-GGA-212380 Formation of TRAP coactivator complex IEA Gallus gallus A0A1D5PKY6 R-GGA-212432 https://reactome.org/PathwayBrowser/#/R-GGA-212432 Formation of DRIP coactivator complex IEA Gallus gallus A0A1D5PKY6 R-GGA-9843120 https://reactome.org/PathwayBrowser/#/R-GGA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1D5PKZ0 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus A0A1D5PKZ0 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1D5PKZ0 R-GGA-444620 https://reactome.org/PathwayBrowser/#/R-GGA-444620 Neuropeptide S receptor binds neuropeptide S IEA Gallus gallus A0A1D5PKZ0 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1D5PKZ0 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1D5PL16 R-GGA-3108212 https://reactome.org/PathwayBrowser/#/R-GGA-3108212 SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 IEA Gallus gallus A0A1D5PL36 R-GGA-8874745 https://reactome.org/PathwayBrowser/#/R-GGA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH IEA Gallus gallus A0A1D5PL38 R-GGA-508040 https://reactome.org/PathwayBrowser/#/R-GGA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Gallus gallus A0A1D5PL38 R-GGA-9837978 https://reactome.org/PathwayBrowser/#/R-GGA-9837978 LONP1 binds mitochondrial inner membrane proteins IEA Gallus gallus A0A1D5PL38 R-GGA-9838004 https://reactome.org/PathwayBrowser/#/R-GGA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Gallus gallus A0A1D5PL70 R-GGA-9013009 https://reactome.org/PathwayBrowser/#/R-GGA-9013009 RHOA binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PL70 R-GGA-9013024 https://reactome.org/PathwayBrowser/#/R-GGA-9013024 RHOB binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PL70 R-GGA-9013110 https://reactome.org/PathwayBrowser/#/R-GGA-9013110 RHOC binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PL70 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PL70 R-GGA-9014294 https://reactome.org/PathwayBrowser/#/R-GGA-9014294 RAC2 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PL70 R-GGA-9014449 https://reactome.org/PathwayBrowser/#/R-GGA-9014449 RHOG binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PL70 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PL70 R-GGA-9693125 https://reactome.org/PathwayBrowser/#/R-GGA-9693125 RHOF binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PL70 R-GGA-9693198 https://reactome.org/PathwayBrowser/#/R-GGA-9693198 RHOD binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PL72 R-GGA-8940100 https://reactome.org/PathwayBrowser/#/R-GGA-8940100 CDK1 phosphorylates VCPIP1 IEA Gallus gallus A0A1D5PL80 R-GGA-1606273 https://reactome.org/PathwayBrowser/#/R-GGA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Gallus gallus A0A1D5PL80 R-GGA-5626981 https://reactome.org/PathwayBrowser/#/R-GGA-5626981 TNF-α:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 IEA Gallus gallus A0A1D5PL88 R-GGA-190519 https://reactome.org/PathwayBrowser/#/R-GGA-190519 Internalization of gap junction plaques IEA Gallus gallus A0A1D5PL88 R-GGA-190829 https://reactome.org/PathwayBrowser/#/R-GGA-190829 Lysosomal degradation of gap junction plaques IEA Gallus gallus A0A1D5PL88 R-GGA-196017 https://reactome.org/PathwayBrowser/#/R-GGA-196017 Dynamin is recruited to the gap junction plaque IEA Gallus gallus A0A1D5PL88 R-GGA-196026 https://reactome.org/PathwayBrowser/#/R-GGA-196026 Dab2 is recruited to the junctional plaques IEA Gallus gallus A0A1D5PL88 R-GGA-3928654 https://reactome.org/PathwayBrowser/#/R-GGA-3928654 Clathrin internalises EPH:EFN complexes IEA Gallus gallus A0A1D5PL88 R-GGA-5140747 https://reactome.org/PathwayBrowser/#/R-GGA-5140747 FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner IEA Gallus gallus A0A1D5PL88 R-GGA-5333658 https://reactome.org/PathwayBrowser/#/R-GGA-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Gallus gallus A0A1D5PL88 R-GGA-8856813 https://reactome.org/PathwayBrowser/#/R-GGA-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Gallus gallus A0A1D5PL88 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5PL88 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5PL88 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5PL88 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5PL88 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5PL88 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5PL88 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5PL88 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5PL88 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PL88 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PL88 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5PL88 R-GGA-8871196 https://reactome.org/PathwayBrowser/#/R-GGA-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Gallus gallus A0A1D5PL93 R-GGA-2574840 https://reactome.org/PathwayBrowser/#/R-GGA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Gallus gallus A0A1D5PL93 R-GGA-2574845 https://reactome.org/PathwayBrowser/#/R-GGA-2574845 AJUBA binds centrosome-associated AURKA IEA Gallus gallus A0A1D5PL93 R-GGA-3000310 https://reactome.org/PathwayBrowser/#/R-GGA-3000310 AURKA phosphorylates PLK1 IEA Gallus gallus A0A1D5PL93 R-GGA-3000319 https://reactome.org/PathwayBrowser/#/R-GGA-3000319 BORA binds PLK1 and AURKA IEA Gallus gallus A0A1D5PL93 R-GGA-380272 https://reactome.org/PathwayBrowser/#/R-GGA-380272 Plk1-mediated phosphorylation of Nlp IEA Gallus gallus A0A1D5PL93 R-GGA-380283 https://reactome.org/PathwayBrowser/#/R-GGA-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Gallus gallus A0A1D5PL93 R-GGA-380294 https://reactome.org/PathwayBrowser/#/R-GGA-380294 Loss of C-Nap-1 from centrosomes IEA Gallus gallus A0A1D5PL93 R-GGA-380311 https://reactome.org/PathwayBrowser/#/R-GGA-380311 Recruitment of Plk1 to centrosomes IEA Gallus gallus A0A1D5PL93 R-GGA-380455 https://reactome.org/PathwayBrowser/#/R-GGA-380455 Recruitment of CDK11p58 to the centrosomes IEA Gallus gallus A0A1D5PL93 R-GGA-380508 https://reactome.org/PathwayBrowser/#/R-GGA-380508 Translocation of NuMA to the centrosomes IEA Gallus gallus A0A1D5PL93 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5PL93 R-GGA-5626228 https://reactome.org/PathwayBrowser/#/R-GGA-5626228 The distal appendage proteins recruit TTBK2 IEA Gallus gallus A0A1D5PL93 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1D5PL93 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1D5PL93 R-GGA-8853405 https://reactome.org/PathwayBrowser/#/R-GGA-8853405 TPX2 binds AURKA at centrosomes IEA Gallus gallus A0A1D5PL93 R-GGA-8853419 https://reactome.org/PathwayBrowser/#/R-GGA-8853419 TPX2 promotes AURKA autophosphorylation IEA Gallus gallus A0A1D5PLA3 R-GGA-3295579 https://reactome.org/PathwayBrowser/#/R-GGA-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Gallus gallus A0A1D5PLA3 R-GGA-9701055 https://reactome.org/PathwayBrowser/#/R-GGA-9701055 TRPA1 tetramer transports Ca2+ from extracellular region to cytosol IEA Gallus gallus A0A1D5PLA3 R-GGA-9701211 https://reactome.org/PathwayBrowser/#/R-GGA-9701211 TRPA1 tetramer binds TRPA1 antagonists IEA Gallus gallus A0A1D5PLC4 R-GGA-5696872 https://reactome.org/PathwayBrowser/#/R-GGA-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Gallus gallus A0A1D5PLC4 R-GGA-8956099 https://reactome.org/PathwayBrowser/#/R-GGA-8956099 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 IEA Gallus gallus A0A1D5PLC4 R-GGA-9755304 https://reactome.org/PathwayBrowser/#/R-GGA-9755304 MUL1 ubiquitinates UBXN7 IEA Gallus gallus A0A1D5PLD2 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5PLD2 R-GGA-6809011 https://reactome.org/PathwayBrowser/#/R-GGA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Gallus gallus A0A1D5PLD2 R-GGA-6811431 https://reactome.org/PathwayBrowser/#/R-GGA-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Gallus gallus A0A1D5PLD2 R-GGA-6811433 https://reactome.org/PathwayBrowser/#/R-GGA-6811433 The COG tethering complex interacts with numerous SNAREs at the Golgi membrane IEA Gallus gallus A0A1D5PLD2 R-GGA-6814682 https://reactome.org/PathwayBrowser/#/R-GGA-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Gallus gallus A0A1D5PLD2 R-GGA-8849748 https://reactome.org/PathwayBrowser/#/R-GGA-8849748 The COG complex binds RABs at the Golgi membrane IEA Gallus gallus A0A1D5PLD8 R-GGA-380283 https://reactome.org/PathwayBrowser/#/R-GGA-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Gallus gallus A0A1D5PLD8 R-GGA-380508 https://reactome.org/PathwayBrowser/#/R-GGA-380508 Translocation of NuMA to the centrosomes IEA Gallus gallus A0A1D5PLE1 R-GGA-1454916 https://reactome.org/PathwayBrowser/#/R-GGA-1454916 The ABCC family mediates organic anion transport IEA Gallus gallus A0A1D5PLE2 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus A0A1D5PLE2 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus A0A1D5PLH7 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PLH7 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PLI2 R-GGA-176250 https://reactome.org/PathwayBrowser/#/R-GGA-176250 Binding of ATR-ATRIP to the RPA-ssDNA complex IEA Gallus gallus A0A1D5PLI2 R-GGA-176298 https://reactome.org/PathwayBrowser/#/R-GGA-176298 Activation of claspin IEA Gallus gallus A0A1D5PLI2 R-GGA-5684875 https://reactome.org/PathwayBrowser/#/R-GGA-5684875 Binding of ATR:ATRIP to RPA at resected DNA DSBs IEA Gallus gallus A0A1D5PLI2 R-GGA-5685011 https://reactome.org/PathwayBrowser/#/R-GGA-5685011 ATR activation at DNA DSBs IEA Gallus gallus A0A1D5PLI2 R-GGA-5685156 https://reactome.org/PathwayBrowser/#/R-GGA-5685156 ATR phosphorylates RPA2 IEA Gallus gallus A0A1D5PLI2 R-GGA-5686642 https://reactome.org/PathwayBrowser/#/R-GGA-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Gallus gallus A0A1D5PLI2 R-GGA-5693564 https://reactome.org/PathwayBrowser/#/R-GGA-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Gallus gallus A0A1D5PLI2 R-GGA-5693580 https://reactome.org/PathwayBrowser/#/R-GGA-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Gallus gallus A0A1D5PLI2 R-GGA-6788385 https://reactome.org/PathwayBrowser/#/R-GGA-6788385 The complex of ATR and ATRIP is recruited to ICL-DNA IEA Gallus gallus A0A1D5PLI2 R-GGA-6788392 https://reactome.org/PathwayBrowser/#/R-GGA-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Gallus gallus A0A1D5PLI3 R-GGA-5205649 https://reactome.org/PathwayBrowser/#/R-GGA-5205649 p62 links damaged mitochondria to LC3 IEA Gallus gallus A0A1D5PLI3 R-GGA-5205663 https://reactome.org/PathwayBrowser/#/R-GGA-5205663 LC3 binds the autophagosome membrane Atg5-Atg12 complex IEA Gallus gallus A0A1D5PLI3 R-GGA-5205673 https://reactome.org/PathwayBrowser/#/R-GGA-5205673 p62 binds ubiquitinated mitochondrial substrates IEA Gallus gallus A0A1D5PLI3 R-GGA-9824888 https://reactome.org/PathwayBrowser/#/R-GGA-9824888 OPTN, TBK1 bind ubiquitinated MOM proteins IEA Gallus gallus A0A1D5PLI3 R-GGA-9824892 https://reactome.org/PathwayBrowser/#/R-GGA-9824892 MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria IEA Gallus gallus A0A1D5PLI3 R-GGA-9824894 https://reactome.org/PathwayBrowser/#/R-GGA-9824894 TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins IEA Gallus gallus A0A1D5PLI3 R-GGA-9824897 https://reactome.org/PathwayBrowser/#/R-GGA-9824897 p-S-TBK1 phosphorylates OPTN IEA Gallus gallus A0A1D5PLI3 R-GGA-9835009 https://reactome.org/PathwayBrowser/#/R-GGA-9835009 PRKN binds p-S-Ub:MOM proteins IEA Gallus gallus A0A1D5PLI3 R-GGA-9840807 https://reactome.org/PathwayBrowser/#/R-GGA-9840807 OPTN binds ATG9A IEA Gallus gallus A0A1D5PLI4 R-GGA-2029476 https://reactome.org/PathwayBrowser/#/R-GGA-2029476 Role of myosins in phagosome formation IEA Gallus gallus A0A1D5PLI4 R-GGA-5250930 https://reactome.org/PathwayBrowser/#/R-GGA-5250930 B-WICH recruits histone acetyltransferases IEA Gallus gallus A0A1D5PLI4 R-GGA-5250938 https://reactome.org/PathwayBrowser/#/R-GGA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Gallus gallus A0A1D5PLI4 R-GGA-5250947 https://reactome.org/PathwayBrowser/#/R-GGA-5250947 B-WICH complex binds rDNA promoter IEA Gallus gallus A0A1D5PLI5 R-GGA-1234163 https://reactome.org/PathwayBrowser/#/R-GGA-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Gallus gallus A0A1D5PLI5 R-GGA-1234172 https://reactome.org/PathwayBrowser/#/R-GGA-1234172 Nuclear VBC complex ubiquitinylates HIF-alpha IEA Gallus gallus A0A1D5PLI5 R-GGA-168915 https://reactome.org/PathwayBrowser/#/R-GGA-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex IEA Gallus gallus A0A1D5PLI5 R-GGA-5607728 https://reactome.org/PathwayBrowser/#/R-GGA-5607728 beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex IEA Gallus gallus A0A1D5PLI5 R-GGA-8852127 https://reactome.org/PathwayBrowser/#/R-GGA-8852127 UBA6 conjugates ubiquitin to cytosolic E2 enzymes IEA Gallus gallus A0A1D5PLI5 R-GGA-8852129 https://reactome.org/PathwayBrowser/#/R-GGA-8852129 UBA1 conjugates ubiquitin to cytosolic E2 enzymes IEA Gallus gallus A0A1D5PLI5 R-GGA-8852130 https://reactome.org/PathwayBrowser/#/R-GGA-8852130 UBA1 conjugates ubiquitin to nuclear E2 enzymes IEA Gallus gallus A0A1D5PLI5 R-GGA-8953917 https://reactome.org/PathwayBrowser/#/R-GGA-8953917 PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 IEA Gallus gallus A0A1D5PLI5 R-GGA-8953946 https://reactome.org/PathwayBrowser/#/R-GGA-8953946 PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 IEA Gallus gallus A0A1D5PLI5 R-GGA-8956106 https://reactome.org/PathwayBrowser/#/R-GGA-8956106 VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha IEA Gallus gallus A0A1D5PLI5 R-GGA-9033485 https://reactome.org/PathwayBrowser/#/R-GGA-9033485 PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 IEA Gallus gallus A0A1D5PLI5 R-GGA-9033527 https://reactome.org/PathwayBrowser/#/R-GGA-9033527 PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 IEA Gallus gallus A0A1D5PLI5 R-GGA-9815507 https://reactome.org/PathwayBrowser/#/R-GGA-9815507 MIB2 ubiquitinates CYLD at K338, K530 IEA Gallus gallus A0A1D5PLI5 R-GGA-9815510 https://reactome.org/PathwayBrowser/#/R-GGA-9815510 MIB2 binds CYLD IEA Gallus gallus A0A1D5PLI5 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PLI5 R-GGA-983152 https://reactome.org/PathwayBrowser/#/R-GGA-983152 Transfer of ubiquitin from E1 to E2 IEA Gallus gallus A0A1D5PLI5 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PLI5 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PLI8 R-GGA-202165 https://reactome.org/PathwayBrowser/#/R-GGA-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Gallus gallus A0A1D5PLI8 R-GGA-202168 https://reactome.org/PathwayBrowser/#/R-GGA-202168 Phosphorylation of ZAP-70 by Lck IEA Gallus gallus A0A1D5PLI8 R-GGA-202174 https://reactome.org/PathwayBrowser/#/R-GGA-202174 Activation of ZAP-70 IEA Gallus gallus A0A1D5PLI8 R-GGA-202214 https://reactome.org/PathwayBrowser/#/R-GGA-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Gallus gallus A0A1D5PLI8 R-GGA-202233 https://reactome.org/PathwayBrowser/#/R-GGA-202233 Inactivation of Lck by Csk IEA Gallus gallus A0A1D5PLI8 R-GGA-202248 https://reactome.org/PathwayBrowser/#/R-GGA-202248 Phosphorylation of PLC-gamma1 IEA Gallus gallus A0A1D5PLI8 R-GGA-202291 https://reactome.org/PathwayBrowser/#/R-GGA-202291 Activation of Lck IEA Gallus gallus A0A1D5PLI8 R-GGA-202344 https://reactome.org/PathwayBrowser/#/R-GGA-202344 Recruitment of ZAP-70 to phosphorylated ITAMs IEA Gallus gallus A0A1D5PLI8 R-GGA-2130641 https://reactome.org/PathwayBrowser/#/R-GGA-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Gallus gallus A0A1D5PLI8 R-GGA-2130725 https://reactome.org/PathwayBrowser/#/R-GGA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Gallus gallus A0A1D5PLI8 R-GGA-389758 https://reactome.org/PathwayBrowser/#/R-GGA-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Gallus gallus A0A1D5PLI8 R-GGA-8852200 https://reactome.org/PathwayBrowser/#/R-GGA-8852200 Inactivation of LCK by PTPN22 IEA Gallus gallus A0A1D5PLI8 R-GGA-8855381 https://reactome.org/PathwayBrowser/#/R-GGA-8855381 PTPN22 dephosphorylates ZAP70 IEA Gallus gallus A0A1D5PLI8 R-GGA-8951498 https://reactome.org/PathwayBrowser/#/R-GGA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Gallus gallus A0A1D5PLJ0 R-GGA-165680 https://reactome.org/PathwayBrowser/#/R-GGA-165680 Formation of active mTORC1 complex IEA Gallus gallus A0A1D5PLJ0 R-GGA-165692 https://reactome.org/PathwayBrowser/#/R-GGA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Gallus gallus A0A1D5PLJ0 R-GGA-165718 https://reactome.org/PathwayBrowser/#/R-GGA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Gallus gallus A0A1D5PLJ0 R-GGA-377186 https://reactome.org/PathwayBrowser/#/R-GGA-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Gallus gallus A0A1D5PLJ0 R-GGA-380979 https://reactome.org/PathwayBrowser/#/R-GGA-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Gallus gallus A0A1D5PLJ0 R-GGA-447074 https://reactome.org/PathwayBrowser/#/R-GGA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Gallus gallus A0A1D5PLJ0 R-GGA-5653957 https://reactome.org/PathwayBrowser/#/R-GGA-5653957 Rag dimer formation IEA Gallus gallus A0A1D5PLJ0 R-GGA-5653968 https://reactome.org/PathwayBrowser/#/R-GGA-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Gallus gallus A0A1D5PLJ0 R-GGA-5653974 https://reactome.org/PathwayBrowser/#/R-GGA-5653974 Ragulator binds Rag dimers IEA Gallus gallus A0A1D5PLJ0 R-GGA-5672010 https://reactome.org/PathwayBrowser/#/R-GGA-5672010 Active MTORC1 phosphorylates ULK1 IEA Gallus gallus A0A1D5PLJ0 R-GGA-5672017 https://reactome.org/PathwayBrowser/#/R-GGA-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Gallus gallus A0A1D5PLJ0 R-GGA-5672817 https://reactome.org/PathwayBrowser/#/R-GGA-5672817 Active MTORC1 binds the ULK1 complex IEA Gallus gallus A0A1D5PLJ0 R-GGA-5672824 https://reactome.org/PathwayBrowser/#/R-GGA-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Gallus gallus A0A1D5PLJ0 R-GGA-5672828 https://reactome.org/PathwayBrowser/#/R-GGA-5672828 mTORC1 phosphorylates AKT1S1 IEA Gallus gallus A0A1D5PLJ0 R-GGA-5673768 https://reactome.org/PathwayBrowser/#/R-GGA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Gallus gallus A0A1D5PLJ0 R-GGA-5675790 https://reactome.org/PathwayBrowser/#/R-GGA-5675790 MTORC1 dissociates from ULK complex IEA Gallus gallus A0A1D5PLJ0 R-GGA-8944454 https://reactome.org/PathwayBrowser/#/R-GGA-8944454 mTORC1 phosphorylates MAF1 IEA Gallus gallus A0A1D5PLJ0 R-GGA-8944457 https://reactome.org/PathwayBrowser/#/R-GGA-8944457 MAF1 translocates to the nucleus IEA Gallus gallus A0A1D5PLJ0 R-GGA-8952716 https://reactome.org/PathwayBrowser/#/R-GGA-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Gallus gallus A0A1D5PLJ0 R-GGA-8952726 https://reactome.org/PathwayBrowser/#/R-GGA-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Gallus gallus A0A1D5PLJ0 R-GGA-9639286 https://reactome.org/PathwayBrowser/#/R-GGA-9639286 RRAGC,D exchanges GTP for GDP IEA Gallus gallus A0A1D5PLJ0 R-GGA-9640167 https://reactome.org/PathwayBrowser/#/R-GGA-9640167 RRAGA,B exchanges GDP for GTP IEA Gallus gallus A0A1D5PLJ0 R-GGA-9640168 https://reactome.org/PathwayBrowser/#/R-GGA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Gallus gallus A0A1D5PLJ0 R-GGA-9640175 https://reactome.org/PathwayBrowser/#/R-GGA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Gallus gallus A0A1D5PLJ0 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus A0A1D5PLJ0 R-GGA-9645598 https://reactome.org/PathwayBrowser/#/R-GGA-9645598 RRAGC,D hydrolyzes GTP IEA Gallus gallus A0A1D5PLJ0 R-GGA-9645608 https://reactome.org/PathwayBrowser/#/R-GGA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Gallus gallus A0A1D5PLJ0 R-GGA-9646468 https://reactome.org/PathwayBrowser/#/R-GGA-9646468 mTORC1 binds RHEB:GTP IEA Gallus gallus A0A1D5PLJ7 R-GGA-6797803 https://reactome.org/PathwayBrowser/#/R-GGA-6797803 PTPRD binds SLITRK1-6 IEA Gallus gallus A0A1D5PLJ7 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PLM6 R-GGA-1675795 https://reactome.org/PathwayBrowser/#/R-GGA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Gallus gallus A0A1D5PLM6 R-GGA-1676065 https://reactome.org/PathwayBrowser/#/R-GGA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Gallus gallus A0A1D5PLM8 R-GGA-162873 https://reactome.org/PathwayBrowser/#/R-GGA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate IEA Gallus gallus A0A1D5PLN4 R-GGA-193641 https://reactome.org/PathwayBrowser/#/R-GGA-193641 IKK-beta is recruited IEA Gallus gallus A0A1D5PLN4 R-GGA-193684 https://reactome.org/PathwayBrowser/#/R-GGA-193684 p62 recruits an atypical PKC IEA Gallus gallus A0A1D5PLN4 R-GGA-193694 https://reactome.org/PathwayBrowser/#/R-GGA-193694 p62 is recruited and forms a complex with TRAF6 IEA Gallus gallus A0A1D5PLN4 R-GGA-193703 https://reactome.org/PathwayBrowser/#/R-GGA-193703 IKKbeta is activated IEA Gallus gallus A0A1D5PLN4 R-GGA-193705 https://reactome.org/PathwayBrowser/#/R-GGA-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate IEA Gallus gallus A0A1D5PLN4 R-GGA-204947 https://reactome.org/PathwayBrowser/#/R-GGA-204947 Polyubiquitinated NRIF migrates to the nucleus IEA Gallus gallus A0A1D5PLN4 R-GGA-205008 https://reactome.org/PathwayBrowser/#/R-GGA-205008 Polyubiquitinated NRIF binds to p62 (Sequestosome) IEA Gallus gallus A0A1D5PLN4 R-GGA-209566 https://reactome.org/PathwayBrowser/#/R-GGA-209566 TRAF6 is auto-ubiquitinated IEA Gallus gallus A0A1D5PLN4 R-GGA-507719 https://reactome.org/PathwayBrowser/#/R-GGA-507719 p62:MEKK3 binds to TRAF6 IEA Gallus gallus A0A1D5PLN4 R-GGA-5205649 https://reactome.org/PathwayBrowser/#/R-GGA-5205649 p62 links damaged mitochondria to LC3 IEA Gallus gallus A0A1D5PLN4 R-GGA-5205663 https://reactome.org/PathwayBrowser/#/R-GGA-5205663 LC3 binds the autophagosome membrane Atg5-Atg12 complex IEA Gallus gallus A0A1D5PLN4 R-GGA-5205673 https://reactome.org/PathwayBrowser/#/R-GGA-5205673 p62 binds ubiquitinated mitochondrial substrates IEA Gallus gallus A0A1D5PLN4 R-GGA-9664855 https://reactome.org/PathwayBrowser/#/R-GGA-9664855 MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 IEA Gallus gallus A0A1D5PLN4 R-GGA-9664880 https://reactome.org/PathwayBrowser/#/R-GGA-9664880 MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 IEA Gallus gallus A0A1D5PLN4 R-GGA-9664881 https://reactome.org/PathwayBrowser/#/R-GGA-9664881 NBR1 binds ATM:Ub-p-PEX5:SQSTM1 IEA Gallus gallus A0A1D5PLN4 R-GGA-9664892 https://reactome.org/PathwayBrowser/#/R-GGA-9664892 SQSTM1 binds ATM dimer:Ub-p-PEX5 IEA Gallus gallus A0A1D5PLN4 R-GGA-9759154 https://reactome.org/PathwayBrowser/#/R-GGA-9759154 TRIM21 ubiquitinates SQSTM1 IEA Gallus gallus A0A1D5PLN4 R-GGA-9759158 https://reactome.org/PathwayBrowser/#/R-GGA-9759158 SQSTM1 oligomerizes IEA Gallus gallus A0A1D5PLN4 R-GGA-9759172 https://reactome.org/PathwayBrowser/#/R-GGA-9759172 KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer IEA Gallus gallus A0A1D5PLN4 R-GGA-9766645 https://reactome.org/PathwayBrowser/#/R-GGA-9766645 CUL3:RBX1 ubiquitinates KEAP1 IEA Gallus gallus A0A1D5PLN4 R-GGA-9766656 https://reactome.org/PathwayBrowser/#/R-GGA-9766656 RBX1:CUL3 dissociates from forming autophagosome IEA Gallus gallus A0A1D5PLN4 R-GGA-9766677 https://reactome.org/PathwayBrowser/#/R-GGA-9766677 MAP1LC3B binds KEAP1 and SQSTM1 IEA Gallus gallus A0A1D5PLN4 R-GGA-9766687 https://reactome.org/PathwayBrowser/#/R-GGA-9766687 SESN1,SESN1 bind SQSTM1 and KEAP1 IEA Gallus gallus A0A1D5PLP7 R-GGA-5696358 https://reactome.org/PathwayBrowser/#/R-GGA-5696358 TREM,CD300 binds lipids IEA Gallus gallus A0A1D5PLR9 R-GGA-183036 https://reactome.org/PathwayBrowser/#/R-GGA-183036 Ubiquitination of stimulated EGFR (CBL:GRB2) IEA Gallus gallus A0A1D5PLS2 R-GGA-70975 https://reactome.org/PathwayBrowser/#/R-GGA-70975 CS acetylates OA to citrate IEA Gallus gallus A0A1D5PLS2 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1D5PLS2 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1D5PLS6 R-GGA-1912394 https://reactome.org/PathwayBrowser/#/R-GGA-1912394 NICD1 in complex with RBPJ (CSL) recruits MAML IEA Gallus gallus A0A1D5PLS6 R-GGA-2032794 https://reactome.org/PathwayBrowser/#/R-GGA-2032794 WWTR1 (TAZ), TBX5, and PCAF form a complex IEA Gallus gallus A0A1D5PLS6 R-GGA-212356 https://reactome.org/PathwayBrowser/#/R-GGA-212356 Formation of CSL-NICD coactivator complex IEA Gallus gallus A0A1D5PLS6 R-GGA-5250930 https://reactome.org/PathwayBrowser/#/R-GGA-5250930 B-WICH recruits histone acetyltransferases IEA Gallus gallus A0A1D5PLS6 R-GGA-5250938 https://reactome.org/PathwayBrowser/#/R-GGA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Gallus gallus A0A1D5PLS6 R-GGA-5691381 https://reactome.org/PathwayBrowser/#/R-GGA-5691381 MYSM1 deubiquitinates Histone H2A IEA Gallus gallus A0A1D5PLS6 R-GGA-8878220 https://reactome.org/PathwayBrowser/#/R-GGA-8878220 RUNX3 binds the NOTCH1 coactivator complex IEA Gallus gallus A0A1D5PLS6 R-GGA-8936481 https://reactome.org/PathwayBrowser/#/R-GGA-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Gallus gallus A0A1D5PLS6 R-GGA-8936621 https://reactome.org/PathwayBrowser/#/R-GGA-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Gallus gallus A0A1D5PLS6 R-GGA-8937016 https://reactome.org/PathwayBrowser/#/R-GGA-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Gallus gallus A0A1D5PLS6 R-GGA-8937050 https://reactome.org/PathwayBrowser/#/R-GGA-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Gallus gallus A0A1D5PLS6 R-GGA-9023860 https://reactome.org/PathwayBrowser/#/R-GGA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Gallus gallus A0A1D5PLS6 R-GGA-9620515 https://reactome.org/PathwayBrowser/#/R-GGA-9620515 KAT2B,EP300 acetylate FOXO3 under oxidative stress IEA Gallus gallus A0A1D5PLS6 R-GGA-9677051 https://reactome.org/PathwayBrowser/#/R-GGA-9677051 Formation of the PCAF-ATAC complex IEA Gallus gallus A0A1D5PLU6 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A1D5PLU6 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A1D5PLU6 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A1D5PLU6 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A1D5PLU6 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5PLU6 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5PLU6 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5PLU6 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5PLU6 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5PLU6 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A1D5PLU6 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5PLU6 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1D5PLX0 R-GGA-6807872 https://reactome.org/PathwayBrowser/#/R-GGA-6807872 Active ARF recruits coatomer IEA Gallus gallus A0A1D5PLX0 R-GGA-6807877 https://reactome.org/PathwayBrowser/#/R-GGA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Gallus gallus A0A1D5PLX0 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1D5PLX0 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5PLX0 R-GGA-6809011 https://reactome.org/PathwayBrowser/#/R-GGA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Gallus gallus A0A1D5PLX0 R-GGA-6811417 https://reactome.org/PathwayBrowser/#/R-GGA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Gallus gallus A0A1D5PLX0 R-GGA-6811418 https://reactome.org/PathwayBrowser/#/R-GGA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Gallus gallus A0A1D5PLX0 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5PLX0 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5PLX8 R-GGA-426240 https://reactome.org/PathwayBrowser/#/R-GGA-426240 DAG kinase produces phosphatidic acid from DAG IEA Gallus gallus A0A1D5PLZ2 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus A0A1D5PLZ2 R-GGA-140696 https://reactome.org/PathwayBrowser/#/R-GGA-140696 factor V -> factor Va + factor V activation peptide (thrombin catalyst) IEA Gallus gallus A0A1D5PLZ2 R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus A0A1D5PLZ2 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus A0A1D5PLZ2 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus A0A1D5PLZ2 R-GGA-5578883 https://reactome.org/PathwayBrowser/#/R-GGA-5578883 Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) IEA Gallus gallus A0A1D5PLZ2 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5PLZ8 R-GGA-1013012 https://reactome.org/PathwayBrowser/#/R-GGA-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Gallus gallus A0A1D5PLZ8 R-GGA-1013013 https://reactome.org/PathwayBrowser/#/R-GGA-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Gallus gallus A0A1D5PLZ8 R-GGA-1013020 https://reactome.org/PathwayBrowser/#/R-GGA-1013020 Activation of GIRK/Kir3 Channels IEA Gallus gallus A0A1D5PLZ8 R-GGA-112271 https://reactome.org/PathwayBrowser/#/R-GGA-112271 The receptor:G-protein complex dissociates IEA Gallus gallus A0A1D5PLZ8 R-GGA-114552 https://reactome.org/PathwayBrowser/#/R-GGA-114552 Thrombin-activated PARs activate G12/13 IEA Gallus gallus A0A1D5PLZ8 R-GGA-114558 https://reactome.org/PathwayBrowser/#/R-GGA-114558 Thrombin-activated PARs activate Gq IEA Gallus gallus A0A1D5PLZ8 R-GGA-167408 https://reactome.org/PathwayBrowser/#/R-GGA-167408 The high affinity receptor complex binds to G-protein IEA Gallus gallus A0A1D5PLZ8 R-GGA-167419 https://reactome.org/PathwayBrowser/#/R-GGA-167419 The receptor:G-protein complex releases GDP IEA Gallus gallus A0A1D5PLZ8 R-GGA-167429 https://reactome.org/PathwayBrowser/#/R-GGA-167429 The receptor:G-protein complex binds GTP IEA Gallus gallus A0A1D5PLZ8 R-GGA-167433 https://reactome.org/PathwayBrowser/#/R-GGA-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Gallus gallus A0A1D5PLZ8 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus A0A1D5PLZ8 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1D5PLZ8 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5PLZ8 R-GGA-392195 https://reactome.org/PathwayBrowser/#/R-GGA-392195 Gi activation by P2Y purinoceptor 12 IEA Gallus gallus A0A1D5PLZ8 R-GGA-392295 https://reactome.org/PathwayBrowser/#/R-GGA-392295 Gbeta:gamma recruits PI3K gamma IEA Gallus gallus A0A1D5PLZ8 R-GGA-392300 https://reactome.org/PathwayBrowser/#/R-GGA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Gallus gallus A0A1D5PLZ8 R-GGA-3965444 https://reactome.org/PathwayBrowser/#/R-GGA-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Gallus gallus A0A1D5PLZ8 R-GGA-3965447 https://reactome.org/PathwayBrowser/#/R-GGA-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Gallus gallus A0A1D5PLZ8 R-GGA-396996 https://reactome.org/PathwayBrowser/#/R-GGA-396996 Thrombin-activated PARs binds G-protein Gq IEA Gallus gallus A0A1D5PLZ8 R-GGA-397835 https://reactome.org/PathwayBrowser/#/R-GGA-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Gallus gallus A0A1D5PLZ8 R-GGA-397891 https://reactome.org/PathwayBrowser/#/R-GGA-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Gallus gallus A0A1D5PLZ8 R-GGA-398040 https://reactome.org/PathwayBrowser/#/R-GGA-398040 Gbeta:gamma activation of PLC beta IEA Gallus gallus A0A1D5PLZ8 R-GGA-398193 https://reactome.org/PathwayBrowser/#/R-GGA-398193 PLC beta-mediated PIP2 hydrolysis IEA Gallus gallus A0A1D5PLZ8 R-GGA-418576 https://reactome.org/PathwayBrowser/#/R-GGA-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Gallus gallus A0A1D5PLZ8 R-GGA-420883 https://reactome.org/PathwayBrowser/#/R-GGA-420883 Opsins act as GEFs for G alpha-t IEA Gallus gallus A0A1D5PLZ8 R-GGA-428749 https://reactome.org/PathwayBrowser/#/R-GGA-428749 Activated TP receptor binds G-proten Gq IEA Gallus gallus A0A1D5PLZ8 R-GGA-428750 https://reactome.org/PathwayBrowser/#/R-GGA-428750 Gq activation by TP receptor IEA Gallus gallus A0A1D5PLZ8 R-GGA-428752 https://reactome.org/PathwayBrowser/#/R-GGA-428752 Dissociation of the TP:Gq complex IEA Gallus gallus A0A1D5PLZ8 R-GGA-428909 https://reactome.org/PathwayBrowser/#/R-GGA-428909 Activated TP receptor binds G-protein G13 IEA Gallus gallus A0A1D5PLZ8 R-GGA-428917 https://reactome.org/PathwayBrowser/#/R-GGA-428917 G13 activation by TP receptor IEA Gallus gallus A0A1D5PLZ8 R-GGA-428918 https://reactome.org/PathwayBrowser/#/R-GGA-428918 Dissociation of the TP:G13 complex IEA Gallus gallus A0A1D5PLZ8 R-GGA-500717 https://reactome.org/PathwayBrowser/#/R-GGA-500717 Activation of GRIK3 homomer IEA Gallus gallus A0A1D5PLZ8 R-GGA-6814418 https://reactome.org/PathwayBrowser/#/R-GGA-6814418 PDCL promotes formation of G-beta:G-gamma heterodimers IEA Gallus gallus A0A1D5PLZ8 R-GGA-749446 https://reactome.org/PathwayBrowser/#/R-GGA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Gallus gallus A0A1D5PLZ8 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1D5PLZ8 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1D5PLZ8 R-GGA-749453 https://reactome.org/PathwayBrowser/#/R-GGA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Gallus gallus A0A1D5PLZ8 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5PLZ8 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5PLZ8 R-GGA-750988 https://reactome.org/PathwayBrowser/#/R-GGA-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Gallus gallus A0A1D5PLZ8 R-GGA-750993 https://reactome.org/PathwayBrowser/#/R-GGA-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Gallus gallus A0A1D5PLZ8 R-GGA-751001 https://reactome.org/PathwayBrowser/#/R-GGA-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Gallus gallus A0A1D5PLZ8 R-GGA-751019 https://reactome.org/PathwayBrowser/#/R-GGA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Gallus gallus A0A1D5PLZ8 R-GGA-751024 https://reactome.org/PathwayBrowser/#/R-GGA-751024 The Ligand:GPCR:Gz complex dissociates IEA Gallus gallus A0A1D5PLZ8 R-GGA-751027 https://reactome.org/PathwayBrowser/#/R-GGA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Gallus gallus A0A1D5PLZ8 R-GGA-751029 https://reactome.org/PathwayBrowser/#/R-GGA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Gallus gallus A0A1D5PLZ8 R-GGA-751039 https://reactome.org/PathwayBrowser/#/R-GGA-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Gallus gallus A0A1D5PLZ8 R-GGA-8850560 https://reactome.org/PathwayBrowser/#/R-GGA-8850560 G-protein alpha releases G-protein heterotrimer from PDCL IEA Gallus gallus A0A1D5PLZ8 R-GGA-8964241 https://reactome.org/PathwayBrowser/#/R-GGA-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Gallus gallus A0A1D5PLZ8 R-GGA-8964271 https://reactome.org/PathwayBrowser/#/R-GGA-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Gallus gallus A0A1D5PLZ8 R-GGA-8964317 https://reactome.org/PathwayBrowser/#/R-GGA-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Gallus gallus A0A1D5PLZ8 R-GGA-8964599 https://reactome.org/PathwayBrowser/#/R-GGA-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Gallus gallus A0A1D5PLZ8 R-GGA-8964604 https://reactome.org/PathwayBrowser/#/R-GGA-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Gallus gallus A0A1D5PLZ8 R-GGA-8964605 https://reactome.org/PathwayBrowser/#/R-GGA-8964605 PAK1:ARHGEF6 complex binds G-protein beta-gamma complex IEA Gallus gallus A0A1D5PLZ8 R-GGA-8964614 https://reactome.org/PathwayBrowser/#/R-GGA-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Gallus gallus A0A1D5PLZ8 R-GGA-8964634 https://reactome.org/PathwayBrowser/#/R-GGA-8964634 CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex IEA Gallus gallus A0A1D5PLZ8 R-GGA-8982637 https://reactome.org/PathwayBrowser/#/R-GGA-8982637 Opsins binds G alpha-t IEA Gallus gallus A0A1D5PLZ8 R-GGA-8982640 https://reactome.org/PathwayBrowser/#/R-GGA-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Gallus gallus A0A1D5PLZ8 R-GGA-9021596 https://reactome.org/PathwayBrowser/#/R-GGA-9021596 Membrane estrogen receptors bind SRC IEA Gallus gallus A0A1D5PLZ8 R-GGA-9021600 https://reactome.org/PathwayBrowser/#/R-GGA-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Gallus gallus A0A1D5PLZ8 R-GGA-9021601 https://reactome.org/PathwayBrowser/#/R-GGA-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Gallus gallus A0A1D5PLZ8 R-GGA-9036301 https://reactome.org/PathwayBrowser/#/R-GGA-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Gallus gallus A0A1D5PLZ8 R-GGA-9036307 https://reactome.org/PathwayBrowser/#/R-GGA-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Gallus gallus A0A1D5PM03 R-GGA-140355 https://reactome.org/PathwayBrowser/#/R-GGA-140355 Arachidonate is oxidised to PGG2 by PTGS1 IEA Gallus gallus A0A1D5PM03 R-GGA-140359 https://reactome.org/PathwayBrowser/#/R-GGA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Gallus gallus A0A1D5PM03 R-GGA-2314678 https://reactome.org/PathwayBrowser/#/R-GGA-2314678 ASA- acetylates PTGS1 IEA Gallus gallus A0A1D5PM03 R-GGA-9677320 https://reactome.org/PathwayBrowser/#/R-GGA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Gallus gallus A0A1D5PM03 R-GGA-9716838 https://reactome.org/PathwayBrowser/#/R-GGA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Gallus gallus A0A1D5PM19 R-GGA-2029476 https://reactome.org/PathwayBrowser/#/R-GGA-2029476 Role of myosins in phagosome formation IEA Gallus gallus A0A1D5PM19 R-GGA-5668932 https://reactome.org/PathwayBrowser/#/R-GGA-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Gallus gallus A0A1D5PM27 R-GGA-8867344 https://reactome.org/PathwayBrowser/#/R-GGA-8867344 OMA1 hydrolyses OPA1 IEA Gallus gallus A0A1D5PM49 R-GGA-1630304 https://reactome.org/PathwayBrowser/#/R-GGA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Gallus gallus A0A1D5PM49 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5PM63 R-GGA-1254248 https://reactome.org/PathwayBrowser/#/R-GGA-1254248 Translocation of ERBB4s80:YAP1 complex to the nucleus IEA Gallus gallus A0A1D5PM63 R-GGA-1254251 https://reactome.org/PathwayBrowser/#/R-GGA-1254251 ERBB4s80 binds YAP1 IEA Gallus gallus A0A1D5PM63 R-GGA-2028583 https://reactome.org/PathwayBrowser/#/R-GGA-2028583 Phosphorylation of YAP by LATS2 IEA Gallus gallus A0A1D5PM63 R-GGA-2028598 https://reactome.org/PathwayBrowser/#/R-GGA-2028598 Phosphorylation of YAP by LATS1 IEA Gallus gallus A0A1D5PM63 R-GGA-2028644 https://reactome.org/PathwayBrowser/#/R-GGA-2028644 YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 IEA Gallus gallus A0A1D5PM63 R-GGA-2028724 https://reactome.org/PathwayBrowser/#/R-GGA-2028724 AMOT proteins bind YAP1 IEA Gallus gallus A0A1D5PM63 R-GGA-2032770 https://reactome.org/PathwayBrowser/#/R-GGA-2032770 Translocation of YAP1 to the nucleus IEA Gallus gallus A0A1D5PM63 R-GGA-2032775 https://reactome.org/PathwayBrowser/#/R-GGA-2032775 YAP1 binds TEAD1 IEA Gallus gallus A0A1D5PM63 R-GGA-2064406 https://reactome.org/PathwayBrowser/#/R-GGA-2064406 Translocation of YAP1:ZO-2 (TJP2) to the nucleus IEA Gallus gallus A0A1D5PM63 R-GGA-2064421 https://reactome.org/PathwayBrowser/#/R-GGA-2064421 YAP1 binds ZO-2 (TJP2) IEA Gallus gallus A0A1D5PM63 R-GGA-8871265 https://reactome.org/PathwayBrowser/#/R-GGA-8871265 YAP1 binds TEAD4 IEA Gallus gallus A0A1D5PM63 R-GGA-8871266 https://reactome.org/PathwayBrowser/#/R-GGA-8871266 YAP1 binds TEAD3 IEA Gallus gallus A0A1D5PM63 R-GGA-8951676 https://reactome.org/PathwayBrowser/#/R-GGA-8951676 RUNX3 binds TEADs and YAP1 IEA Gallus gallus A0A1D5PM63 R-GGA-8956639 https://reactome.org/PathwayBrowser/#/R-GGA-8956639 RUNX1 binds YAP1 IEA Gallus gallus A0A1D5PM63 R-GGA-8956659 https://reactome.org/PathwayBrowser/#/R-GGA-8956659 ABL1 phosphorylates YAP1 IEA Gallus gallus A0A1D5PM63 R-GGA-8956676 https://reactome.org/PathwayBrowser/#/R-GGA-8956676 YAP1 binds TP73 IEA Gallus gallus A0A1D5PM63 R-GGA-9865176 https://reactome.org/PathwayBrowser/#/R-GGA-9865176 p-Y407-YAP1 translocates from the cytosol to the nucleoplasm IEA Gallus gallus A0A1D5PM63 R-GGA-9865196 https://reactome.org/PathwayBrowser/#/R-GGA-9865196 p-Y393-ABL1 phosphorylates tyrosine-407 of YAP1 IEA Gallus gallus A0A1D5PM63 R-GGA-9865226 https://reactome.org/PathwayBrowser/#/R-GGA-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Gallus gallus A0A1D5PM72 R-GGA-193064 https://reactome.org/PathwayBrowser/#/R-GGA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Gallus gallus A0A1D5PM72 R-GGA-548818 https://reactome.org/PathwayBrowser/#/R-GGA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Gallus gallus A0A1D5PM73 R-GGA-1675780 https://reactome.org/PathwayBrowser/#/R-GGA-1675780 PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane IEA Gallus gallus A0A1D5PM73 R-GGA-1675813 https://reactome.org/PathwayBrowser/#/R-GGA-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Gallus gallus A0A1D5PM73 R-GGA-1675974 https://reactome.org/PathwayBrowser/#/R-GGA-1675974 PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane IEA Gallus gallus A0A1D5PM73 R-GGA-1676185 https://reactome.org/PathwayBrowser/#/R-GGA-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Gallus gallus A0A1D5PM87 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5PM87 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5PM87 R-GGA-2466068 https://reactome.org/PathwayBrowser/#/R-GGA-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Gallus gallus A0A1D5PM87 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5PM87 R-GGA-2468039 https://reactome.org/PathwayBrowser/#/R-GGA-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Gallus gallus A0A1D5PM87 R-GGA-2468040 https://reactome.org/PathwayBrowser/#/R-GGA-2468040 Cohesin binds PDS5 and WAPAL IEA Gallus gallus A0A1D5PM87 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5PM87 R-GGA-2468293 https://reactome.org/PathwayBrowser/#/R-GGA-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Gallus gallus A0A1D5PM87 R-GGA-2470935 https://reactome.org/PathwayBrowser/#/R-GGA-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Gallus gallus A0A1D5PM87 R-GGA-2473152 https://reactome.org/PathwayBrowser/#/R-GGA-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Gallus gallus A0A1D5PM87 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5PM87 R-GGA-2545203 https://reactome.org/PathwayBrowser/#/R-GGA-2545203 Deacetylation of cleaved cohesin IEA Gallus gallus A0A1D5PM87 R-GGA-2545253 https://reactome.org/PathwayBrowser/#/R-GGA-2545253 Deacetylation of cohesin IEA Gallus gallus A0A1D5PM87 R-GGA-3108212 https://reactome.org/PathwayBrowser/#/R-GGA-3108212 SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 IEA Gallus gallus A0A1D5PM89 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus A0A1D5PM89 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1D5PM89 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1D5PM89 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5PM89 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5PM89 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5PMA0 R-GGA-194130 https://reactome.org/PathwayBrowser/#/R-GGA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Gallus gallus A0A1D5PMA0 R-GGA-9794270 https://reactome.org/PathwayBrowser/#/R-GGA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Gallus gallus A0A1D5PMA2 R-GGA-2032775 https://reactome.org/PathwayBrowser/#/R-GGA-2032775 YAP1 binds TEAD1 IEA Gallus gallus A0A1D5PMA2 R-GGA-2032781 https://reactome.org/PathwayBrowser/#/R-GGA-2032781 WWTR1 (TAZ) binds TEAD IEA Gallus gallus A0A1D5PMA2 R-GGA-8951676 https://reactome.org/PathwayBrowser/#/R-GGA-8951676 RUNX3 binds TEADs and YAP1 IEA Gallus gallus A0A1D5PMB7 R-GGA-1011598 https://reactome.org/PathwayBrowser/#/R-GGA-1011598 DOCKs bind to RhoGEFs IEA Gallus gallus A0A1D5PMB7 R-GGA-9013143 https://reactome.org/PathwayBrowser/#/R-GGA-9013143 RAC1 GEFs activate RAC1 IEA Gallus gallus A0A1D5PMB7 R-GGA-9014296 https://reactome.org/PathwayBrowser/#/R-GGA-9014296 RAC2 GEFs activate RAC2 IEA Gallus gallus A0A1D5PMB7 R-GGA-9014449 https://reactome.org/PathwayBrowser/#/R-GGA-9014449 RHOG binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PMB7 R-GGA-9032798 https://reactome.org/PathwayBrowser/#/R-GGA-9032798 DOCK3 activates RAC1 IEA Gallus gallus A0A1D5PMC0 R-GGA-265682 https://reactome.org/PathwayBrowser/#/R-GGA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Gallus gallus A0A1D5PMC0 R-GGA-381608 https://reactome.org/PathwayBrowser/#/R-GGA-381608 cAMP activates EPAC2 IEA Gallus gallus A0A1D5PMC0 R-GGA-381727 https://reactome.org/PathwayBrowser/#/R-GGA-381727 RAP1A exchanges GDP for GTP IEA Gallus gallus A0A1D5PMC0 R-GGA-392834 https://reactome.org/PathwayBrowser/#/R-GGA-392834 Activation of EPACs by cAMP IEA Gallus gallus A0A1D5PMC0 R-GGA-939265 https://reactome.org/PathwayBrowser/#/R-GGA-939265 Activation of Rap1 by membrane-associated GEFs IEA Gallus gallus A0A1D5PMC2 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus A0A1D5PMC2 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus A0A1D5PMC2 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus A0A1D5PMC2 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus A0A1D5PMC2 R-GGA-5694423 https://reactome.org/PathwayBrowser/#/R-GGA-5694423 NSF and SNAPs bind cis-SNARE complex IEA Gallus gallus A0A1D5PMC2 R-GGA-5694425 https://reactome.org/PathwayBrowser/#/R-GGA-5694425 NSF ATPase activity dissociates cis-SNARE IEA Gallus gallus A0A1D5PMC2 R-GGA-5694446 https://reactome.org/PathwayBrowser/#/R-GGA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Gallus gallus A0A1D5PMC9 R-GGA-445448 https://reactome.org/PathwayBrowser/#/R-GGA-445448 HHIP binds Hedgehog IEA Gallus gallus A0A1D5PMC9 R-GGA-5358336 https://reactome.org/PathwayBrowser/#/R-GGA-5358336 P4HB forms mixed disulphides with Hh precursors IEA Gallus gallus A0A1D5PMC9 R-GGA-5358340 https://reactome.org/PathwayBrowser/#/R-GGA-5358340 Autoproteolytic cleavage of Hh precursors IEA Gallus gallus A0A1D5PMC9 R-GGA-5358343 https://reactome.org/PathwayBrowser/#/R-GGA-5358343 HHAT palmitoylates Hh N-terminal fragment IEA Gallus gallus A0A1D5PMC9 R-GGA-5362386 https://reactome.org/PathwayBrowser/#/R-GGA-5362386 Glycosylation of Hh IEA Gallus gallus A0A1D5PMC9 R-GGA-5362412 https://reactome.org/PathwayBrowser/#/R-GGA-5362412 SYVN1 ubiquitinates Hh C-terminal fragments IEA Gallus gallus A0A1D5PMC9 R-GGA-5362427 https://reactome.org/PathwayBrowser/#/R-GGA-5362427 Hh-Np binds GPC5 IEA Gallus gallus A0A1D5PMC9 R-GGA-5362437 https://reactome.org/PathwayBrowser/#/R-GGA-5362437 C-terminal Hh fragments are bound by lectins IEA Gallus gallus A0A1D5PMC9 R-GGA-5362441 https://reactome.org/PathwayBrowser/#/R-GGA-5362441 C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane IEA Gallus gallus A0A1D5PMC9 R-GGA-5362448 https://reactome.org/PathwayBrowser/#/R-GGA-5362448 Hh C-terminal fragments are degraded by the proteasome IEA Gallus gallus A0A1D5PMC9 R-GGA-5362459 https://reactome.org/PathwayBrowser/#/R-GGA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Gallus gallus A0A1D5PMC9 R-GGA-5362549 https://reactome.org/PathwayBrowser/#/R-GGA-5362549 Hh-Np traffics to the plasma membrane IEA Gallus gallus A0A1D5PMC9 R-GGA-5362553 https://reactome.org/PathwayBrowser/#/R-GGA-5362553 NOTUM releases Hh-Np:GPC5 from the plasma membrane IEA Gallus gallus A0A1D5PMC9 R-GGA-5632652 https://reactome.org/PathwayBrowser/#/R-GGA-5632652 Hh-Npp binds CDON and PTCH IEA Gallus gallus A0A1D5PMD9 R-GGA-5693691 https://reactome.org/PathwayBrowser/#/R-GGA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Gallus gallus A0A1D5PMD9 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus A0A1D5PMD9 R-GGA-9727567 https://reactome.org/PathwayBrowser/#/R-GGA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Gallus gallus A0A1D5PMD9 R-GGA-9749792 https://reactome.org/PathwayBrowser/#/R-GGA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Gallus gallus A0A1D5PMF4 R-GGA-6798745 https://reactome.org/PathwayBrowser/#/R-GGA-6798745 Exocytosis of tertiary granule lumen proteins IEA Gallus gallus A0A1D5PMF4 R-GGA-6798749 https://reactome.org/PathwayBrowser/#/R-GGA-6798749 Exocytosis of specific granule lumen proteins IEA Gallus gallus A0A1D5PMI2 R-GGA-9934021 https://reactome.org/PathwayBrowser/#/R-GGA-9934021 Formation of neuronal progenitor BAF (npBAF) IEA Gallus gallus A0A1D5PMI2 R-GGA-9934024 https://reactome.org/PathwayBrowser/#/R-GGA-9934024 SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10 IEA Gallus gallus A0A1D5PMI7 R-GGA-9629591 https://reactome.org/PathwayBrowser/#/R-GGA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Gallus gallus A0A1D5PMK5 R-GGA-1296127 https://reactome.org/PathwayBrowser/#/R-GGA-1296127 Activation of voltage gated Potassium channels IEA Gallus gallus A0A1D5PML9 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus A0A1D5PML9 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus A0A1D5PML9 R-GGA-9013143 https://reactome.org/PathwayBrowser/#/R-GGA-9013143 RAC1 GEFs activate RAC1 IEA Gallus gallus A0A1D5PMM2 R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus A0A1D5PMM2 R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus A0A1D5PMM2 R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus A0A1D5PMN3 R-GGA-111439 https://reactome.org/PathwayBrowser/#/R-GGA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Gallus gallus A0A1D5PMN3 R-GGA-158441 https://reactome.org/PathwayBrowser/#/R-GGA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PMN3 R-GGA-158447 https://reactome.org/PathwayBrowser/#/R-GGA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Gallus gallus A0A1D5PMN3 R-GGA-158481 https://reactome.org/PathwayBrowser/#/R-GGA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PMN3 R-GGA-158484 https://reactome.org/PathwayBrowser/#/R-GGA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Gallus gallus A0A1D5PMN3 R-GGA-159046 https://reactome.org/PathwayBrowser/#/R-GGA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Gallus gallus A0A1D5PMN3 R-GGA-159050 https://reactome.org/PathwayBrowser/#/R-GGA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Gallus gallus A0A1D5PMN3 R-GGA-170825 https://reactome.org/PathwayBrowser/#/R-GGA-170825 NPC exports GCK1 from nucleus IEA Gallus gallus A0A1D5PMN3 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1D5PMN3 R-GGA-2990880 https://reactome.org/PathwayBrowser/#/R-GGA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Gallus gallus A0A1D5PMN3 R-GGA-2990882 https://reactome.org/PathwayBrowser/#/R-GGA-2990882 CDK1 phosphorylates NUP98 IEA Gallus gallus A0A1D5PMN3 R-GGA-4551649 https://reactome.org/PathwayBrowser/#/R-GGA-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Gallus gallus A0A1D5PMN3 R-GGA-4551679 https://reactome.org/PathwayBrowser/#/R-GGA-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Gallus gallus A0A1D5PMN3 R-GGA-4615872 https://reactome.org/PathwayBrowser/#/R-GGA-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Gallus gallus A0A1D5PMN3 R-GGA-4615987 https://reactome.org/PathwayBrowser/#/R-GGA-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Gallus gallus A0A1D5PMN3 R-GGA-4655355 https://reactome.org/PathwayBrowser/#/R-GGA-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Gallus gallus A0A1D5PMN3 R-GGA-5228523 https://reactome.org/PathwayBrowser/#/R-GGA-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Gallus gallus A0A1D5PMN3 R-GGA-5578744 https://reactome.org/PathwayBrowser/#/R-GGA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Gallus gallus A0A1D5PMN3 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1D5PMN3 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1D5PMN3 R-GGA-77587 https://reactome.org/PathwayBrowser/#/R-GGA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Gallus gallus A0A1D5PMN7 R-GGA-73589 https://reactome.org/PathwayBrowser/#/R-GGA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Gallus gallus A0A1D5PMN7 R-GGA-73618 https://reactome.org/PathwayBrowser/#/R-GGA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Gallus gallus A0A1D5PMP0 R-GGA-212252 https://reactome.org/PathwayBrowser/#/R-GGA-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Gallus gallus A0A1D5PMP0 R-GGA-212263 https://reactome.org/PathwayBrowser/#/R-GGA-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Gallus gallus A0A1D5PMQ5 R-GGA-6805546 https://reactome.org/PathwayBrowser/#/R-GGA-6805546 Keratin type I binds keratin type II IEA Gallus gallus A0A1D5PMQ5 R-GGA-6805573 https://reactome.org/PathwayBrowser/#/R-GGA-6805573 Keratin type I/type II heterodimers form tetramers IEA Gallus gallus A0A1D5PMQ5 R-GGA-6806610 https://reactome.org/PathwayBrowser/#/R-GGA-6806610 Keratin filament formation IEA Gallus gallus A0A1D5PMQ5 R-GGA-6806613 https://reactome.org/PathwayBrowser/#/R-GGA-6806613 Keratin tetramers bind to form unit length filaments IEA Gallus gallus A0A1D5PMQ5 R-GGA-6806629 https://reactome.org/PathwayBrowser/#/R-GGA-6806629 Formation of tonofilament bundles IEA Gallus gallus A0A1D5PMQ5 R-GGA-6809393 https://reactome.org/PathwayBrowser/#/R-GGA-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Gallus gallus A0A1D5PMQ5 R-GGA-6810357 https://reactome.org/PathwayBrowser/#/R-GGA-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Gallus gallus A0A1D5PMR8 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus A0A1D5PMR8 R-GGA-77591 https://reactome.org/PathwayBrowser/#/R-GGA-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Gallus gallus A0A1D5PMR8 R-GGA-77592 https://reactome.org/PathwayBrowser/#/R-GGA-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Gallus gallus A0A1D5PMR8 R-GGA-77593 https://reactome.org/PathwayBrowser/#/R-GGA-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Gallus gallus A0A1D5PMR8 R-GGA-9018778 https://reactome.org/PathwayBrowser/#/R-GGA-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Gallus gallus A0A1D5PMT8 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1D5PMT8 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1D5PMT8 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1D5PMT8 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1D5PMT8 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1D5PMT8 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5PMT8 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5PMT9 R-GGA-9843120 https://reactome.org/PathwayBrowser/#/R-GGA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1D5PMU1 R-GGA-1482889 https://reactome.org/PathwayBrowser/#/R-GGA-1482889 DAG is acylated to TAG by DGAT1/2 IEA Gallus gallus A0A1D5PMU1 R-GGA-549192 https://reactome.org/PathwayBrowser/#/R-GGA-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Gallus gallus A0A1D5PMV1 R-GGA-202710 https://reactome.org/PathwayBrowser/#/R-GGA-202710 MERTK receptor binds ligands (Gas6 or Protein S) IEA Gallus gallus A0A1D5PMW0 R-GGA-6805546 https://reactome.org/PathwayBrowser/#/R-GGA-6805546 Keratin type I binds keratin type II IEA Gallus gallus A0A1D5PMW0 R-GGA-6805573 https://reactome.org/PathwayBrowser/#/R-GGA-6805573 Keratin type I/type II heterodimers form tetramers IEA Gallus gallus A0A1D5PMW0 R-GGA-6806610 https://reactome.org/PathwayBrowser/#/R-GGA-6806610 Keratin filament formation IEA Gallus gallus A0A1D5PMW0 R-GGA-6806613 https://reactome.org/PathwayBrowser/#/R-GGA-6806613 Keratin tetramers bind to form unit length filaments IEA Gallus gallus A0A1D5PMW0 R-GGA-6806629 https://reactome.org/PathwayBrowser/#/R-GGA-6806629 Formation of tonofilament bundles IEA Gallus gallus A0A1D5PMW0 R-GGA-6809393 https://reactome.org/PathwayBrowser/#/R-GGA-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Gallus gallus A0A1D5PMW0 R-GGA-6810357 https://reactome.org/PathwayBrowser/#/R-GGA-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Gallus gallus A0A1D5PMW3 R-GGA-114256 https://reactome.org/PathwayBrowser/#/R-GGA-114256 CYCS:APAF1 binds procaspase-9 IEA Gallus gallus A0A1D5PMW3 R-GGA-6804596 https://reactome.org/PathwayBrowser/#/R-GGA-6804596 APAF1:CYCS binds APIP IEA Gallus gallus A0A1D5PMY0 R-GGA-8952618 https://reactome.org/PathwayBrowser/#/R-GGA-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PMY0 R-GGA-8952620 https://reactome.org/PathwayBrowser/#/R-GGA-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PMY0 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5PMY0 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5PMY0 R-GGA-8956200 https://reactome.org/PathwayBrowser/#/R-GGA-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PMY0 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PMY0 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PMY0 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PMY0 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PMY5 R-GGA-3000434 https://reactome.org/PathwayBrowser/#/R-GGA-3000434 PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1 IEA Gallus gallus A0A1D5PMY5 R-GGA-8850997 https://reactome.org/PathwayBrowser/#/R-GGA-8850997 TRIM27 binds PTEN IEA Gallus gallus A0A1D5PMY5 R-GGA-8851011 https://reactome.org/PathwayBrowser/#/R-GGA-8851011 TRIM27 polyubiquitinates PTEN IEA Gallus gallus A0A1D5PMZ7 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5PN05 R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus A0A1D5PN05 R-GGA-9709406 https://reactome.org/PathwayBrowser/#/R-GGA-9709406 CO binds to Cytochrome c oxidase IEA Gallus gallus A0A1D5PN14 R-GGA-1454916 https://reactome.org/PathwayBrowser/#/R-GGA-1454916 The ABCC family mediates organic anion transport IEA Gallus gallus A0A1D5PN14 R-GGA-2142859 https://reactome.org/PathwayBrowser/#/R-GGA-2142859 Growing HA is extruded from the cell by ABCC5 IEA Gallus gallus A0A1D5PN14 R-GGA-9750617 https://reactome.org/PathwayBrowser/#/R-GGA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus A0A1D5PN14 R-GGA-9753284 https://reactome.org/PathwayBrowser/#/R-GGA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Gallus gallus A0A1D5PN19 R-GGA-2162078 https://reactome.org/PathwayBrowser/#/R-GGA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Gallus gallus A0A1D5PN19 R-GGA-5362564 https://reactome.org/PathwayBrowser/#/R-GGA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Gallus gallus A0A1D5PN19 R-GGA-71707 https://reactome.org/PathwayBrowser/#/R-GGA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Gallus gallus A0A1D5PN24 R-GGA-9619376 https://reactome.org/PathwayBrowser/#/R-GGA-9619376 CAMK1 binds calmodulin IEA Gallus gallus A0A1D5PN25 R-GGA-72103 https://reactome.org/PathwayBrowser/#/R-GGA-72103 Formation of pre-mRNPs IEA Gallus gallus A0A1D5PN25 R-GGA-75079 https://reactome.org/PathwayBrowser/#/R-GGA-75079 Formation of AT-AC C complex IEA Gallus gallus A0A1D5PN25 R-GGA-75081 https://reactome.org/PathwayBrowser/#/R-GGA-75081 Formation of AT-AC B Complex IEA Gallus gallus A0A1D5PN25 R-GGA-75082 https://reactome.org/PathwayBrowser/#/R-GGA-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Gallus gallus A0A1D5PN25 R-GGA-75083 https://reactome.org/PathwayBrowser/#/R-GGA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Gallus gallus A0A1D5PN25 R-GGA-9017797 https://reactome.org/PathwayBrowser/#/R-GGA-9017797 NOTCH3 binds YBX1 IEA Gallus gallus A0A1D5PN25 R-GGA-9017817 https://reactome.org/PathwayBrowser/#/R-GGA-9017817 Gamma-secretase cleaves YBX1:NOTCH3 IEA Gallus gallus A0A1D5PN25 R-GGA-9734547 https://reactome.org/PathwayBrowser/#/R-GGA-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Gallus gallus A0A1D5PN25 R-GGA-9736836 https://reactome.org/PathwayBrowser/#/R-GGA-9736836 Phosphorylated YBX1 translocates to the nucleus IEA Gallus gallus A0A1D5PN25 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5PN36 R-GGA-1454822 https://reactome.org/PathwayBrowser/#/R-GGA-1454822 Collagen type I degradation by MMP1,2,8,13, PRSS2 IEA Gallus gallus A0A1D5PN36 R-GGA-1474197 https://reactome.org/PathwayBrowser/#/R-GGA-1474197 Collagen type II degradation by MMP1,3,8,13,PRSS2 IEA Gallus gallus A0A1D5PN36 R-GGA-1592316 https://reactome.org/PathwayBrowser/#/R-GGA-1592316 Initial activation of proMMP1 IEA Gallus gallus A0A1D5PN36 R-GGA-1592371 https://reactome.org/PathwayBrowser/#/R-GGA-1592371 Initial activation of proMMP3 IEA Gallus gallus A0A1D5PN36 R-GGA-1592398 https://reactome.org/PathwayBrowser/#/R-GGA-1592398 Activation of proMMP8 IEA Gallus gallus A0A1D5PN36 R-GGA-1602458 https://reactome.org/PathwayBrowser/#/R-GGA-1602458 Activation of proMMP10 IEA Gallus gallus A0A1D5PN36 R-GGA-1602488 https://reactome.org/PathwayBrowser/#/R-GGA-1602488 Initial activation of proMMP13 by plasmin and trypsin IEA Gallus gallus A0A1D5PN36 R-GGA-1604712 https://reactome.org/PathwayBrowser/#/R-GGA-1604712 Initial activation of proMMP7 by trypsin IEA Gallus gallus A0A1D5PN36 R-GGA-1604722 https://reactome.org/PathwayBrowser/#/R-GGA-1604722 Activation of proMMP9 by proteases IEA Gallus gallus A0A1D5PN36 R-GGA-6798745 https://reactome.org/PathwayBrowser/#/R-GGA-6798745 Exocytosis of tertiary granule lumen proteins IEA Gallus gallus A0A1D5PN36 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5PN46 R-GGA-70479 https://reactome.org/PathwayBrowser/#/R-GGA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Gallus gallus A0A1D5PN47 R-GGA-350058 https://reactome.org/PathwayBrowser/#/R-GGA-350058 Formation of CSL NCOR corepressor complex IEA Gallus gallus A0A1D5PN47 R-GGA-3782655 https://reactome.org/PathwayBrowser/#/R-GGA-3782655 HDAC10 deacetylates histone IEA Gallus gallus A0A1D5PN50 R-GGA-212222 https://reactome.org/PathwayBrowser/#/R-GGA-212222 PRC2 recruits DNA methyltransferases IEA Gallus gallus A0A1D5PN50 R-GGA-212252 https://reactome.org/PathwayBrowser/#/R-GGA-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Gallus gallus A0A1D5PN50 R-GGA-212263 https://reactome.org/PathwayBrowser/#/R-GGA-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Gallus gallus A0A1D5PN50 R-GGA-212269 https://reactome.org/PathwayBrowser/#/R-GGA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Gallus gallus A0A1D5PN50 R-GGA-3240295 https://reactome.org/PathwayBrowser/#/R-GGA-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Gallus gallus A0A1D5PN50 R-GGA-8943817 https://reactome.org/PathwayBrowser/#/R-GGA-8943817 MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter IEA Gallus gallus A0A1D5PN50 R-GGA-8954110 https://reactome.org/PathwayBrowser/#/R-GGA-8954110 E2F6:TFDP1:EPC1 binds the PRC2 complex IEA Gallus gallus A0A1D5PN54 R-GGA-164832 https://reactome.org/PathwayBrowser/#/R-GGA-164832 ATPase synthesizes ATP IEA Gallus gallus A0A1D5PN54 R-GGA-164834 https://reactome.org/PathwayBrowser/#/R-GGA-164834 Enzyme-bound ATP is released IEA Gallus gallus A0A1D5PN54 R-GGA-164840 https://reactome.org/PathwayBrowser/#/R-GGA-164840 ADP and Pi bind to ATPase IEA Gallus gallus A0A1D5PN54 R-GGA-8949580 https://reactome.org/PathwayBrowser/#/R-GGA-8949580 F1Fo ATP synthase dimerizes IEA Gallus gallus A0A1D5PN54 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1D5PN54 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1D5PN54 R-GGA-9839105 https://reactome.org/PathwayBrowser/#/R-GGA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1D5PN54 R-GGA-9839149 https://reactome.org/PathwayBrowser/#/R-GGA-9839149 AFG3L2 binds mitochondrial matrix proteins IEA Gallus gallus A0A1D5PN84 R-GGA-1955380 https://reactome.org/PathwayBrowser/#/R-GGA-1955380 TIMM9:TIMM10 transfers proteins to TIMM22 IEA Gallus gallus A0A1D5PN96 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus A0A1D5PN96 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus A0A1D5PN97 R-GGA-1237096 https://reactome.org/PathwayBrowser/#/R-GGA-1237096 Methylthio-ribose-P => Methylthio-ribulose-P IEA Gallus gallus A0A1D5PN97 R-GGA-1299507 https://reactome.org/PathwayBrowser/#/R-GGA-1299507 Methylthio-ribulose-P => Methylthio-ribose-P IEA Gallus gallus A0A1D5PNA2 R-GGA-8865605 https://reactome.org/PathwayBrowser/#/R-GGA-8865605 BRWD1 binds SMARCA4 IEA Gallus gallus A0A1D5PNA2 R-GGA-8865613 https://reactome.org/PathwayBrowser/#/R-GGA-8865613 BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3 IEA Gallus gallus A0A1D5PNA6 R-GGA-111930 https://reactome.org/PathwayBrowser/#/R-GGA-111930 Adenylate cyclase produces cAMP IEA Gallus gallus A0A1D5PNA6 R-GGA-170666 https://reactome.org/PathwayBrowser/#/R-GGA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Gallus gallus A0A1D5PNA6 R-GGA-170671 https://reactome.org/PathwayBrowser/#/R-GGA-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Gallus gallus A0A1D5PNA6 R-GGA-170672 https://reactome.org/PathwayBrowser/#/R-GGA-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Gallus gallus A0A1D5PNA6 R-GGA-170674 https://reactome.org/PathwayBrowser/#/R-GGA-170674 Dissociation of the Gi alpha:G olf complex IEA Gallus gallus A0A1D5PNA6 R-GGA-170676 https://reactome.org/PathwayBrowser/#/R-GGA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Gallus gallus A0A1D5PNA6 R-GGA-170677 https://reactome.org/PathwayBrowser/#/R-GGA-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Gallus gallus A0A1D5PNA6 R-GGA-170685 https://reactome.org/PathwayBrowser/#/R-GGA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Gallus gallus A0A1D5PNA6 R-GGA-170686 https://reactome.org/PathwayBrowser/#/R-GGA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Gallus gallus A0A1D5PNA6 R-GGA-392064 https://reactome.org/PathwayBrowser/#/R-GGA-392064 G alpha (z) inhibits adenylate cyclase IEA Gallus gallus A0A1D5PNA6 R-GGA-5610727 https://reactome.org/PathwayBrowser/#/R-GGA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Gallus gallus A0A1D5PNB4 R-GGA-202706 https://reactome.org/PathwayBrowser/#/R-GGA-202706 Integrin alpha4beta1 binds JAM2:JAM3 IEA Gallus gallus A0A1D5PNB4 R-GGA-204434 https://reactome.org/PathwayBrowser/#/R-GGA-204434 BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 IEA Gallus gallus A0A1D5PNB4 R-GGA-216045 https://reactome.org/PathwayBrowser/#/R-GGA-216045 Collagen type I binds integrin alpha11beta1 IEA Gallus gallus A0A1D5PNB4 R-GGA-216050 https://reactome.org/PathwayBrowser/#/R-GGA-216050 Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix IEA Gallus gallus A0A1D5PNB4 R-GGA-216064 https://reactome.org/PathwayBrowser/#/R-GGA-216064 Interaction of integrin alpha8beta1 with Tenascin-C IEA Gallus gallus A0A1D5PNB4 R-GGA-216068 https://reactome.org/PathwayBrowser/#/R-GGA-216068 Interaction of integrin alpha9beta1 with Tenascin-C IEA Gallus gallus A0A1D5PNB4 R-GGA-2395320 https://reactome.org/PathwayBrowser/#/R-GGA-2395320 Latent TGF-beta-1 binds integrins IEA Gallus gallus A0A1D5PNB4 R-GGA-2396029 https://reactome.org/PathwayBrowser/#/R-GGA-2396029 Latent TGF-beta-3 binds integrins IEA Gallus gallus A0A1D5PNB4 R-GGA-2426471 https://reactome.org/PathwayBrowser/#/R-GGA-2426471 VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 IEA Gallus gallus A0A1D5PNB4 R-GGA-265424 https://reactome.org/PathwayBrowser/#/R-GGA-265424 SPP1 (osteopontin) binds integrin alpha5beta1, alpha9beta1 IEA Gallus gallus A0A1D5PNB4 R-GGA-265429 https://reactome.org/PathwayBrowser/#/R-GGA-265429 THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1 IEA Gallus gallus A0A1D5PNB4 R-GGA-2681667 https://reactome.org/PathwayBrowser/#/R-GGA-2681667 TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 IEA Gallus gallus A0A1D5PNB4 R-GGA-2731074 https://reactome.org/PathwayBrowser/#/R-GGA-2731074 Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) IEA Gallus gallus A0A1D5PNB4 R-GGA-4084912 https://reactome.org/PathwayBrowser/#/R-GGA-4084912 Arresten binds integrin alpha1beta1 IEA Gallus gallus A0A1D5PNB4 R-GGA-4085133 https://reactome.org/PathwayBrowser/#/R-GGA-4085133 LUM (lumican) binds integrin alpha2beta1 IEA Gallus gallus A0A1D5PNB4 R-GGA-8874079 https://reactome.org/PathwayBrowser/#/R-GGA-8874079 PTK2 binds activated MET IEA Gallus gallus A0A1D5PNB4 R-GGA-8875531 https://reactome.org/PathwayBrowser/#/R-GGA-8875531 MET binds TNS4 IEA Gallus gallus A0A1D5PNB4 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PNB4 R-GGA-9014294 https://reactome.org/PathwayBrowser/#/R-GGA-9014294 RAC2 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PNB4 R-GGA-9014449 https://reactome.org/PathwayBrowser/#/R-GGA-9014449 RHOG binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PNB4 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PNB4 R-GGA-9679740 https://reactome.org/PathwayBrowser/#/R-GGA-9679740 ITGA4:ITGB1 binds natalizumab IEA Gallus gallus A0A1D5PNB4 R-GGA-9861484 https://reactome.org/PathwayBrowser/#/R-GGA-9861484 Phosphorylation of PTK2 (FAK) on tyrosine-397 in response to turbulent blood flow IEA Gallus gallus A0A1D5PNB4 R-GGA-9865184 https://reactome.org/PathwayBrowser/#/R-GGA-9865184 Phosphorylation of ABL1 on tyrosine-393 in response to oscillatory shear stress IEA Gallus gallus A0A1D5PNB4 R-GGA-9865226 https://reactome.org/PathwayBrowser/#/R-GGA-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Gallus gallus A0A1D5PND8 R-GGA-507749 https://reactome.org/PathwayBrowser/#/R-GGA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Gallus gallus A0A1D5PND8 R-GGA-507775 https://reactome.org/PathwayBrowser/#/R-GGA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Gallus gallus A0A1D5PNE7 R-GGA-622325 https://reactome.org/PathwayBrowser/#/R-GGA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Gallus gallus A0A1D5PNE7 R-GGA-629588 https://reactome.org/PathwayBrowser/#/R-GGA-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Gallus gallus A0A1D5PNE8 R-GGA-111930 https://reactome.org/PathwayBrowser/#/R-GGA-111930 Adenylate cyclase produces cAMP IEA Gallus gallus A0A1D5PNE8 R-GGA-170666 https://reactome.org/PathwayBrowser/#/R-GGA-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Gallus gallus A0A1D5PNE8 R-GGA-170671 https://reactome.org/PathwayBrowser/#/R-GGA-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Gallus gallus A0A1D5PNE8 R-GGA-170672 https://reactome.org/PathwayBrowser/#/R-GGA-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Gallus gallus A0A1D5PNE8 R-GGA-170674 https://reactome.org/PathwayBrowser/#/R-GGA-170674 Dissociation of the Gi alpha:G olf complex IEA Gallus gallus A0A1D5PNE8 R-GGA-170676 https://reactome.org/PathwayBrowser/#/R-GGA-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Gallus gallus A0A1D5PNE8 R-GGA-170677 https://reactome.org/PathwayBrowser/#/R-GGA-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Gallus gallus A0A1D5PNE8 R-GGA-170685 https://reactome.org/PathwayBrowser/#/R-GGA-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Gallus gallus A0A1D5PNE8 R-GGA-170686 https://reactome.org/PathwayBrowser/#/R-GGA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Gallus gallus A0A1D5PNE8 R-GGA-392064 https://reactome.org/PathwayBrowser/#/R-GGA-392064 G alpha (z) inhibits adenylate cyclase IEA Gallus gallus A0A1D5PNE8 R-GGA-5610727 https://reactome.org/PathwayBrowser/#/R-GGA-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Gallus gallus A0A1D5PNF3 R-GGA-109699 https://reactome.org/PathwayBrowser/#/R-GGA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Gallus gallus A0A1D5PNF3 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PNF3 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5PNF3 R-GGA-9607304 https://reactome.org/PathwayBrowser/#/R-GGA-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Gallus gallus A0A1D5PNF3 R-GGA-9698170 https://reactome.org/PathwayBrowser/#/R-GGA-9698170 Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA IEA Gallus gallus A0A1D5PNF3 R-GGA-9706345 https://reactome.org/PathwayBrowser/#/R-GGA-9706345 Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA IEA Gallus gallus A0A1D5PNG0 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PNH0 R-GGA-8952873 https://reactome.org/PathwayBrowser/#/R-GGA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Gallus gallus A0A1D5PNI1 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PNJ7 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1D5PNJ7 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1D5PNJ7 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1D5PNJ7 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1D5PNJ7 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1D5PNJ7 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5PNJ7 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5PNK0 R-GGA-1237129 https://reactome.org/PathwayBrowser/#/R-GGA-1237129 Acireductone is created IEA Gallus gallus A0A1D5PNK3 R-GGA-198440 https://reactome.org/PathwayBrowser/#/R-GGA-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane IEA Gallus gallus A0A1D5PNK3 R-GGA-376851 https://reactome.org/PathwayBrowser/#/R-GGA-376851 SLC25A11 exchanges 2-OG and MAL IEA Gallus gallus A0A1D5PNK7 R-GGA-936883 https://reactome.org/PathwayBrowser/#/R-GGA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Gallus gallus A0A1D5PNM0 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus A0A1D5PNM0 R-GGA-6799178 https://reactome.org/PathwayBrowser/#/R-GGA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Gallus gallus A0A1D5PNM0 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus A0A1D5PNM0 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus A0A1D5PNM0 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus A0A1D5PNM0 R-GGA-6799202 https://reactome.org/PathwayBrowser/#/R-GGA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Gallus gallus A0A1D5PNP5 R-GGA-373751 https://reactome.org/PathwayBrowser/#/R-GGA-373751 UNC-5 binds Netrin-1 IEA Gallus gallus A0A1D5PNR0 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus A0A1D5PNR0 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1D5PNR0 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1D5PNR0 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5PNR0 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5PNR0 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5PNR3 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus A0A1D5PNR3 R-GGA-416588 https://reactome.org/PathwayBrowser/#/R-GGA-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Gallus gallus A0A1D5PNR3 R-GGA-416594 https://reactome.org/PathwayBrowser/#/R-GGA-416594 LARG and PDZ-RhoGEF binds to Plexin-B1 IEA Gallus gallus A0A1D5PNR3 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus A0A1D5PNR3 R-GGA-8980691 https://reactome.org/PathwayBrowser/#/R-GGA-8980691 RHOA GEFs activate RHOA IEA Gallus gallus A0A1D5PNR3 R-GGA-9013023 https://reactome.org/PathwayBrowser/#/R-GGA-9013023 RHOB GEFs activate RHOB IEA Gallus gallus A0A1D5PNR3 R-GGA-9013109 https://reactome.org/PathwayBrowser/#/R-GGA-9013109 RHOC GEFs activate RHOC IEA Gallus gallus A0A1D5PNR3 R-GGA-9013143 https://reactome.org/PathwayBrowser/#/R-GGA-9013143 RAC1 GEFs activate RAC1 IEA Gallus gallus A0A1D5PNR3 R-GGA-9013159 https://reactome.org/PathwayBrowser/#/R-GGA-9013159 CDC42 GEFs activate CDC42 IEA Gallus gallus A0A1D5PNR4 R-GGA-3322995 https://reactome.org/PathwayBrowser/#/R-GGA-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Gallus gallus A0A1D5PNS4 R-GGA-201622 https://reactome.org/PathwayBrowser/#/R-GGA-201622 Caspase-mediated cleavage of gelsolin IEA Gallus gallus A0A1D5PNS4 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PNS4 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PNT7 R-GGA-1971483 https://reactome.org/PathwayBrowser/#/R-GGA-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Gallus gallus A0A1D5PNT9 R-GGA-5676229 https://reactome.org/PathwayBrowser/#/R-GGA-5676229 WIPIs bind PI3P IEA Gallus gallus A0A1D5PNU2 R-GGA-481009 https://reactome.org/PathwayBrowser/#/R-GGA-481009 Exocytosis of platelet dense granule content IEA Gallus gallus A0A1D5PNU9 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus A0A1D5PNU9 R-GGA-390835 https://reactome.org/PathwayBrowser/#/R-GGA-390835 DRD1,5 bind DA IEA Gallus gallus A0A1D5PNV1 R-GGA-70609 https://reactome.org/PathwayBrowser/#/R-GGA-70609 glutamine + H2O => glutamate + NH4+ (GLS) IEA Gallus gallus A0A1D5PNV3 R-GGA-8950181 https://reactome.org/PathwayBrowser/#/R-GGA-8950181 Y693-STAT4 dimer translocates to the nucleus IEA Gallus gallus A0A1D5PNV3 R-GGA-8950269 https://reactome.org/PathwayBrowser/#/R-GGA-8950269 STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor IEA Gallus gallus A0A1D5PNV3 R-GGA-8950448 https://reactome.org/PathwayBrowser/#/R-GGA-8950448 STAT4 binds to IL12RB2 in Interleukin-12 receptor complex IEA Gallus gallus A0A1D5PNV3 R-GGA-8950453 https://reactome.org/PathwayBrowser/#/R-GGA-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Gallus gallus A0A1D5PNV3 R-GGA-8950522 https://reactome.org/PathwayBrowser/#/R-GGA-8950522 p-STAT1:p-STAT4 translocates to the nucleus IEA Gallus gallus A0A1D5PNV3 R-GGA-8950724 https://reactome.org/PathwayBrowser/#/R-GGA-8950724 p-Y705-STAT3:p-Y693-STAT4 translocates to the nucleus IEA Gallus gallus A0A1D5PNV3 R-GGA-8950778 https://reactome.org/PathwayBrowser/#/R-GGA-8950778 p-Y693-STAT4 dimerizes IEA Gallus gallus A0A1D5PNV3 R-GGA-8950780 https://reactome.org/PathwayBrowser/#/R-GGA-8950780 p-Y705-STAT3 binds p-Y693-STAT4 IEA Gallus gallus A0A1D5PNV3 R-GGA-8952749 https://reactome.org/PathwayBrowser/#/R-GGA-8952749 STAT4 binds p-Y-IL23R in IL23:IL23 receptor IEA Gallus gallus A0A1D5PNV3 R-GGA-8952807 https://reactome.org/PathwayBrowser/#/R-GGA-8952807 p-Y693-STAT4 dissociates after IL12:IL12R interaction IEA Gallus gallus A0A1D5PNV3 R-GGA-8952823 https://reactome.org/PathwayBrowser/#/R-GGA-8952823 p-Y693-STAT4, p-Y705-STAT3 dissociate from IL23:IL23 receptor IEA Gallus gallus A0A1D5PNV3 R-GGA-8983872 https://reactome.org/PathwayBrowser/#/R-GGA-8983872 JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 IEA Gallus gallus A0A1D5PNV3 R-GGA-8983876 https://reactome.org/PathwayBrowser/#/R-GGA-8983876 STAT4 binds IL12RB2:IL12RB2 IEA Gallus gallus A0A1D5PNV3 R-GGA-8983878 https://reactome.org/PathwayBrowser/#/R-GGA-8983878 p-STAT4 dissociates from IL12RB2:IL12RB2 receptor IEA Gallus gallus A0A1D5PNV3 R-GGA-8983983 https://reactome.org/PathwayBrowser/#/R-GGA-8983983 p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor IEA Gallus gallus A0A1D5PNV3 R-GGA-8983996 https://reactome.org/PathwayBrowser/#/R-GGA-8983996 STAT1 and STAT4 associate with IL12RB2:IL6ST receptor IEA Gallus gallus A0A1D5PNV3 R-GGA-8986985 https://reactome.org/PathwayBrowser/#/R-GGA-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Gallus gallus A0A1D5PNV3 R-GGA-8987033 https://reactome.org/PathwayBrowser/#/R-GGA-8987033 p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 IEA Gallus gallus A0A1D5PNV3 R-GGA-8987266 https://reactome.org/PathwayBrowser/#/R-GGA-8987266 IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 IEA Gallus gallus A0A1D5PNV3 R-GGA-9006870 https://reactome.org/PathwayBrowser/#/R-GGA-9006870 IL21 receptor STAT phosphorylation IEA Gallus gallus A0A1D5PNV3 R-GGA-9006873 https://reactome.org/PathwayBrowser/#/R-GGA-9006873 IL21 receptor STAT binding IEA Gallus gallus A0A1D5PNW3 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus A0A1D5PNW6 R-GGA-5626981 https://reactome.org/PathwayBrowser/#/R-GGA-5626981 TNF-α:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 IEA Gallus gallus A0A1D5PNX0 R-GGA-880002 https://reactome.org/PathwayBrowser/#/R-GGA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Gallus gallus A0A1D5PNX0 R-GGA-880033 https://reactome.org/PathwayBrowser/#/R-GGA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Gallus gallus A0A1D5PNY8 R-GGA-173483 https://reactome.org/PathwayBrowser/#/R-GGA-173483 BAMBI interferes with the interaction of type I receptor with type II receptor IEA Gallus gallus A0A1D5PNY8 R-GGA-173512 https://reactome.org/PathwayBrowser/#/R-GGA-173512 I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) IEA Gallus gallus A0A1D5PNY8 R-GGA-178208 https://reactome.org/PathwayBrowser/#/R-GGA-178208 SMAD7 binds to SMURF2 IEA Gallus gallus A0A1D5PNY8 R-GGA-201475 https://reactome.org/PathwayBrowser/#/R-GGA-201475 I-Smad competes with R-Smad1/5/8 for type I receptor IEA Gallus gallus A0A1D5PNY8 R-GGA-201821 https://reactome.org/PathwayBrowser/#/R-GGA-201821 I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated IEA Gallus gallus A0A1D5PNY8 R-GGA-202626 https://reactome.org/PathwayBrowser/#/R-GGA-202626 I-Smad competes with Co-Smad for R-Smad1/5/8 IEA Gallus gallus A0A1D5PNY8 R-GGA-2128994 https://reactome.org/PathwayBrowser/#/R-GGA-2128994 STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 IEA Gallus gallus A0A1D5PNY8 R-GGA-2169046 https://reactome.org/PathwayBrowser/#/R-GGA-2169046 Degradation of TGF-beta receptor complex IEA Gallus gallus A0A1D5PNY8 R-GGA-2186771 https://reactome.org/PathwayBrowser/#/R-GGA-2186771 RNF111 binds SMAD7 IEA Gallus gallus A0A1D5PNY8 R-GGA-2186780 https://reactome.org/PathwayBrowser/#/R-GGA-2186780 Degradation of Ub-SMAD7 IEA Gallus gallus A0A1D5PNY8 R-GGA-6781764 https://reactome.org/PathwayBrowser/#/R-GGA-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Gallus gallus A0A1D5PP00 R-GGA-5665998 https://reactome.org/PathwayBrowser/#/R-GGA-5665998 MKL1 binds SRF IEA Gallus gallus A0A1D5PP00 R-GGA-5666008 https://reactome.org/PathwayBrowser/#/R-GGA-5666008 SCAI binds SRF:MKL1 IEA Gallus gallus A0A1D5PP00 R-GGA-9612509 https://reactome.org/PathwayBrowser/#/R-GGA-9612509 SGK phosphorylates SRF IEA Gallus gallus A0A1D5PP06 R-GGA-6798745 https://reactome.org/PathwayBrowser/#/R-GGA-6798745 Exocytosis of tertiary granule lumen proteins IEA Gallus gallus A0A1D5PP06 R-GGA-6798749 https://reactome.org/PathwayBrowser/#/R-GGA-6798749 Exocytosis of specific granule lumen proteins IEA Gallus gallus A0A1D5PP06 R-GGA-9861563 https://reactome.org/PathwayBrowser/#/R-GGA-9861563 CTLH E3 ligase ubiquitinates LDHA IEA Gallus gallus A0A1D5PP06 R-GGA-9861640 https://reactome.org/PathwayBrowser/#/R-GGA-9861640 CTLH E3 ligase ubiquitinates PKM-1 IEA Gallus gallus A0A1D5PP14 R-GGA-5654510 https://reactome.org/PathwayBrowser/#/R-GGA-5654510 FGFRL1 binds SPRED1/2 IEA Gallus gallus A0A1D5PP14 R-GGA-5658231 https://reactome.org/PathwayBrowser/#/R-GGA-5658231 RAS GAPs stimulate RAS GTPase activity IEA Gallus gallus A0A1D5PP14 R-GGA-5658430 https://reactome.org/PathwayBrowser/#/R-GGA-5658430 NF1 is degraded by the proteasome IEA Gallus gallus A0A1D5PP14 R-GGA-5658435 https://reactome.org/PathwayBrowser/#/R-GGA-5658435 RAS GAPs bind RAS:GTP IEA Gallus gallus A0A1D5PP14 R-GGA-5658438 https://reactome.org/PathwayBrowser/#/R-GGA-5658438 SPRED dimer binds NF1 IEA Gallus gallus A0A1D5PP16 R-GGA-428625 https://reactome.org/PathwayBrowser/#/R-GGA-428625 Vesicular inhibitory amino acid transport IEA Gallus gallus A0A1D5PP16 R-GGA-888592 https://reactome.org/PathwayBrowser/#/R-GGA-888592 Loading of GABA into clathrin sculpted GABA transport vesicle lumen IEA Gallus gallus A0A1D5PP20 R-GGA-111962 https://reactome.org/PathwayBrowser/#/R-GGA-111962 PDE4A,C,D hydrolyse cAMP IEA Gallus gallus A0A1D5PP20 R-GGA-418553 https://reactome.org/PathwayBrowser/#/R-GGA-418553 cAMP degradation by Phosphodiesterases IEA Gallus gallus A0A1D5PP20 R-GGA-9865226 https://reactome.org/PathwayBrowser/#/R-GGA-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Gallus gallus A0A1D5PP28 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1D5PP34 R-GGA-265177 https://reactome.org/PathwayBrowser/#/R-GGA-265177 Exocyst complex formation IEA Gallus gallus A0A1D5PP34 R-GGA-5623524 https://reactome.org/PathwayBrowser/#/R-GGA-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Gallus gallus A0A1D5PP34 R-GGA-5623527 https://reactome.org/PathwayBrowser/#/R-GGA-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Gallus gallus A0A1D5PP40 R-GGA-166214 https://reactome.org/PathwayBrowser/#/R-GGA-166214 FA anion flip-flops to the opposite surface IEA Gallus gallus A0A1D5PP40 R-GGA-166220 https://reactome.org/PathwayBrowser/#/R-GGA-166220 FA anion diffuses laterally to UCP IEA Gallus gallus A0A1D5PP40 R-GGA-166387 https://reactome.org/PathwayBrowser/#/R-GGA-166387 The FA anion diffuses away laterally from UCP IEA Gallus gallus A0A1D5PP57 R-GGA-1222516 https://reactome.org/PathwayBrowser/#/R-GGA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Gallus gallus A0A1D5PP57 R-GGA-74723 https://reactome.org/PathwayBrowser/#/R-GGA-74723 Endosome acidification IEA Gallus gallus A0A1D5PP57 R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus A0A1D5PP57 R-GGA-9639286 https://reactome.org/PathwayBrowser/#/R-GGA-9639286 RRAGC,D exchanges GTP for GDP IEA Gallus gallus A0A1D5PP57 R-GGA-9640167 https://reactome.org/PathwayBrowser/#/R-GGA-9640167 RRAGA,B exchanges GDP for GTP IEA Gallus gallus A0A1D5PP57 R-GGA-9640168 https://reactome.org/PathwayBrowser/#/R-GGA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Gallus gallus A0A1D5PP57 R-GGA-9640175 https://reactome.org/PathwayBrowser/#/R-GGA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Gallus gallus A0A1D5PP57 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus A0A1D5PP57 R-GGA-9645598 https://reactome.org/PathwayBrowser/#/R-GGA-9645598 RRAGC,D hydrolyzes GTP IEA Gallus gallus A0A1D5PP57 R-GGA-9645608 https://reactome.org/PathwayBrowser/#/R-GGA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Gallus gallus A0A1D5PP57 R-GGA-9646468 https://reactome.org/PathwayBrowser/#/R-GGA-9646468 mTORC1 binds RHEB:GTP IEA Gallus gallus A0A1D5PP62 R-GGA-372448 https://reactome.org/PathwayBrowser/#/R-GGA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Gallus gallus A0A1D5PP75 R-GGA-975903 https://reactome.org/PathwayBrowser/#/R-GGA-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Gallus gallus A0A1D5PP82 R-GGA-3782535 https://reactome.org/PathwayBrowser/#/R-GGA-3782535 TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1 IEA Gallus gallus A0A1D5PP82 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1D5PP82 R-GGA-9842833 https://reactome.org/PathwayBrowser/#/R-GGA-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Gallus gallus A0A1D5PP82 R-GGA-9842839 https://reactome.org/PathwayBrowser/#/R-GGA-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1D5PP82 R-GGA-9843978 https://reactome.org/PathwayBrowser/#/R-GGA-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1D5PP83 R-GGA-1296127 https://reactome.org/PathwayBrowser/#/R-GGA-1296127 Activation of voltage gated Potassium channels IEA Gallus gallus A0A1D5PP85 R-GGA-449803 https://reactome.org/PathwayBrowser/#/R-GGA-449803 IL10 dimer binds IL10RA:JAK1 IEA Gallus gallus A0A1D5PP85 R-GGA-449811 https://reactome.org/PathwayBrowser/#/R-GGA-449811 IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 IEA Gallus gallus A0A1D5PP85 R-GGA-6784006 https://reactome.org/PathwayBrowser/#/R-GGA-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Gallus gallus A0A1D5PP85 R-GGA-6784319 https://reactome.org/PathwayBrowser/#/R-GGA-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Gallus gallus A0A1D5PP85 R-GGA-6784323 https://reactome.org/PathwayBrowser/#/R-GGA-6784323 IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 IEA Gallus gallus A0A1D5PP85 R-GGA-6784324 https://reactome.org/PathwayBrowser/#/R-GGA-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Gallus gallus A0A1D5PP85 R-GGA-6784791 https://reactome.org/PathwayBrowser/#/R-GGA-6784791 p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 IEA Gallus gallus A0A1D5PPC7 R-GGA-1632857 https://reactome.org/PathwayBrowser/#/R-GGA-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Gallus gallus A0A1D5PPC7 R-GGA-200421 https://reactome.org/PathwayBrowser/#/R-GGA-200421 Activation of cytosolic AMPK by phosphorylation IEA Gallus gallus A0A1D5PPC7 R-GGA-380930 https://reactome.org/PathwayBrowser/#/R-GGA-380930 Phosphorylated AMPK binds AMP IEA Gallus gallus A0A1D5PPC7 R-GGA-380949 https://reactome.org/PathwayBrowser/#/R-GGA-380949 AMPK is dephosphorylated IEA Gallus gallus A0A1D5PPC7 R-GGA-447074 https://reactome.org/PathwayBrowser/#/R-GGA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Gallus gallus A0A1D5PPC7 R-GGA-5631941 https://reactome.org/PathwayBrowser/#/R-GGA-5631941 SESN1,2,3 bind AMPK IEA Gallus gallus A0A1D5PPC7 R-GGA-5665868 https://reactome.org/PathwayBrowser/#/R-GGA-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Gallus gallus A0A1D5PPC7 R-GGA-5672008 https://reactome.org/PathwayBrowser/#/R-GGA-5672008 Thr-180 of ULK1 is phosphorylated IEA Gallus gallus A0A1D5PPC7 R-GGA-5672011 https://reactome.org/PathwayBrowser/#/R-GGA-5672011 p-AMPK:AMP binds the ULK complex IEA Gallus gallus A0A1D5PPC7 R-GGA-5673768 https://reactome.org/PathwayBrowser/#/R-GGA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Gallus gallus A0A1D5PPC7 R-GGA-5675868 https://reactome.org/PathwayBrowser/#/R-GGA-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Gallus gallus A0A1D5PPC7 R-GGA-5679205 https://reactome.org/PathwayBrowser/#/R-GGA-5679205 ULK1 phosphorylates Beclin-1 IEA Gallus gallus A0A1D5PPC7 R-GGA-5679239 https://reactome.org/PathwayBrowser/#/R-GGA-5679239 ULK complex translocates to the ER IEA Gallus gallus A0A1D5PPD0 R-GGA-1234167 https://reactome.org/PathwayBrowser/#/R-GGA-1234167 Formation of HIF:CBP:p300 complex at promoters IEA Gallus gallus A0A1D5PPD0 R-GGA-1912394 https://reactome.org/PathwayBrowser/#/R-GGA-1912394 NICD1 in complex with RBPJ (CSL) recruits MAML IEA Gallus gallus A0A1D5PPD0 R-GGA-212356 https://reactome.org/PathwayBrowser/#/R-GGA-212356 Formation of CSL-NICD coactivator complex IEA Gallus gallus A0A1D5PPD0 R-GGA-3322427 https://reactome.org/PathwayBrowser/#/R-GGA-3322427 Beta-catenin recruits CBP/p300 IEA Gallus gallus A0A1D5PPD0 R-GGA-3371554 https://reactome.org/PathwayBrowser/#/R-GGA-3371554 HSF1 acetylation at Lys80 IEA Gallus gallus A0A1D5PPD0 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus A0A1D5PPD0 R-GGA-5660660 https://reactome.org/PathwayBrowser/#/R-GGA-5660660 p300 acetylates RELA subunit IEA Gallus gallus A0A1D5PPD0 R-GGA-5660666 https://reactome.org/PathwayBrowser/#/R-GGA-5660666 CBP and p300 binds NF-kB complex IEA Gallus gallus A0A1D5PPD0 R-GGA-8864307 https://reactome.org/PathwayBrowser/#/R-GGA-8864307 TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP IEA Gallus gallus A0A1D5PPD0 R-GGA-8878220 https://reactome.org/PathwayBrowser/#/R-GGA-8878220 RUNX3 binds the NOTCH1 coactivator complex IEA Gallus gallus A0A1D5PPD0 R-GGA-8938231 https://reactome.org/PathwayBrowser/#/R-GGA-8938231 RUNX1:CBFB binds CREBBP IEA Gallus gallus A0A1D5PPD0 R-GGA-9038052 https://reactome.org/PathwayBrowser/#/R-GGA-9038052 GREB1 binds ESR1:ESTG and co-activators IEA Gallus gallus A0A1D5PPD0 R-GGA-933536 https://reactome.org/PathwayBrowser/#/R-GGA-933536 p-IRF7 dimer interacts with coactivator CBP/p300 IEA Gallus gallus A0A1D5PPD0 R-GGA-9626928 https://reactome.org/PathwayBrowser/#/R-GGA-9626928 CREBBP binds FOXO1 IEA Gallus gallus A0A1D5PPD0 R-GGA-9760081 https://reactome.org/PathwayBrowser/#/R-GGA-9760081 CREBBP, EP300 acetylates NFE2L2 IEA Gallus gallus A0A1D5PPD0 R-GGA-9760082 https://reactome.org/PathwayBrowser/#/R-GGA-9760082 NFE2L2 binds CREBBP,EP300 IEA Gallus gallus A0A1D5PPD0 R-GGA-9825747 https://reactome.org/PathwayBrowser/#/R-GGA-9825747 CREBBP acetylates HINT1 dimer IEA Gallus gallus A0A1D5PPD0 R-GGA-9825751 https://reactome.org/PathwayBrowser/#/R-GGA-9825751 HINT1 binds MITF-M IEA Gallus gallus A0A1D5PPD0 R-GGA-9843120 https://reactome.org/PathwayBrowser/#/R-GGA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1D5PPD0 R-GGA-9926478 https://reactome.org/PathwayBrowser/#/R-GGA-9926478 MITF-M binds CREBBP,EP300 IEA Gallus gallus A0A1D5PPD2 R-GGA-174374 https://reactome.org/PathwayBrowser/#/R-GGA-174374 MTR transfers CH3 from MeCbl to HCYS IEA Gallus gallus A0A1D5PPD2 R-GGA-3149518 https://reactome.org/PathwayBrowser/#/R-GGA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Gallus gallus A0A1D5PPD2 R-GGA-3149539 https://reactome.org/PathwayBrowser/#/R-GGA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin IEA Gallus gallus A0A1D5PPD2 R-GGA-3204318 https://reactome.org/PathwayBrowser/#/R-GGA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Gallus gallus A0A1D5PPD3 R-GGA-5689950 https://reactome.org/PathwayBrowser/#/R-GGA-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Gallus gallus A0A1D5PPD3 R-GGA-6782069 https://reactome.org/PathwayBrowser/#/R-GGA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Gallus gallus A0A1D5PPD3 R-GGA-6782131 https://reactome.org/PathwayBrowser/#/R-GGA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5PPD3 R-GGA-6782138 https://reactome.org/PathwayBrowser/#/R-GGA-6782138 ERCC5 and RPA bind TC-NER site IEA Gallus gallus A0A1D5PPD3 R-GGA-6782204 https://reactome.org/PathwayBrowser/#/R-GGA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Gallus gallus A0A1D5PPD3 R-GGA-6782208 https://reactome.org/PathwayBrowser/#/R-GGA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Gallus gallus A0A1D5PPD3 R-GGA-6782211 https://reactome.org/PathwayBrowser/#/R-GGA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Gallus gallus A0A1D5PPD3 R-GGA-6782227 https://reactome.org/PathwayBrowser/#/R-GGA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Gallus gallus A0A1D5PPD3 R-GGA-6807118 https://reactome.org/PathwayBrowser/#/R-GGA-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Gallus gallus A0A1D5PPD3 R-GGA-8853503 https://reactome.org/PathwayBrowser/#/R-GGA-8853503 UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin IEA Gallus gallus A0A1D5PPD3 R-GGA-8853514 https://reactome.org/PathwayBrowser/#/R-GGA-8853514 UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin IEA Gallus gallus A0A1D5PPD3 R-GGA-9684118 https://reactome.org/PathwayBrowser/#/R-GGA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5PPF7 R-GGA-9023909 https://reactome.org/PathwayBrowser/#/R-GGA-9023909 C3PO hydrolyzes cleaved passenger strand IEA Gallus gallus A0A1D5PPG4 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1D5PPH8 R-GGA-3640844 https://reactome.org/PathwayBrowser/#/R-GGA-3640844 RNF146 binds RibC-AXIN:TNKS complex IEA Gallus gallus A0A1D5PPH8 R-GGA-3640858 https://reactome.org/PathwayBrowser/#/R-GGA-3640858 Tankyrase ADP-ribosylates AXIN IEA Gallus gallus A0A1D5PPH8 R-GGA-3640861 https://reactome.org/PathwayBrowser/#/R-GGA-3640861 RNF146 ubiquitinates ADP-ribosylated AXIN IEA Gallus gallus A0A1D5PPH8 R-GGA-3640862 https://reactome.org/PathwayBrowser/#/R-GGA-3640862 Tankyrase binds AXIN IEA Gallus gallus A0A1D5PPH8 R-GGA-3640872 https://reactome.org/PathwayBrowser/#/R-GGA-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Gallus gallus A0A1D5PPH8 R-GGA-3640874 https://reactome.org/PathwayBrowser/#/R-GGA-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5PPH8 R-GGA-4641129 https://reactome.org/PathwayBrowser/#/R-GGA-4641129 AXIN is ubiquitinated by SMURF2 IEA Gallus gallus A0A1D5PPH8 R-GGA-4641134 https://reactome.org/PathwayBrowser/#/R-GGA-4641134 SMURF2 binds AXIN IEA Gallus gallus A0A1D5PPH8 R-GGA-4641256 https://reactome.org/PathwayBrowser/#/R-GGA-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Gallus gallus A0A1D5PPH9 R-GGA-3247837 https://reactome.org/PathwayBrowser/#/R-GGA-3247837 WNT ligands traffic to the Golgi IEA Gallus gallus A0A1D5PPH9 R-GGA-3247840 https://reactome.org/PathwayBrowser/#/R-GGA-3247840 WLS binds WNT ligands in the Golgi IEA Gallus gallus A0A1D5PPH9 R-GGA-3247843 https://reactome.org/PathwayBrowser/#/R-GGA-3247843 secretion of WNT ligands IEA Gallus gallus A0A1D5PPH9 R-GGA-3247844 https://reactome.org/PathwayBrowser/#/R-GGA-3247844 WNT ligands traffic to the plasma membrane IEA Gallus gallus A0A1D5PPH9 R-GGA-3781941 https://reactome.org/PathwayBrowser/#/R-GGA-3781941 WNTs are secreted in exosomes IEA Gallus gallus A0A1D5PPH9 R-GGA-3781943 https://reactome.org/PathwayBrowser/#/R-GGA-3781943 WLS:WNT complex is internalized for maturation into exosomes IEA Gallus gallus A0A1D5PPI5 R-GGA-70577 https://reactome.org/PathwayBrowser/#/R-GGA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Gallus gallus A0A1D5PPI7 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5PPI7 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5PPI7 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5PPI7 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5PPI7 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5PPJ3 R-GGA-5578712 https://reactome.org/PathwayBrowser/#/R-GGA-5578712 Importin-8 binds AGO2:miRNA IEA Gallus gallus A0A1D5PPJ3 R-GGA-5578744 https://reactome.org/PathwayBrowser/#/R-GGA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Gallus gallus A0A1D5PPK6 R-GGA-5173005 https://reactome.org/PathwayBrowser/#/R-GGA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Gallus gallus A0A1D5PPK6 R-GGA-5173192 https://reactome.org/PathwayBrowser/#/R-GGA-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Gallus gallus A0A1D5PPN9 R-GGA-1678923 https://reactome.org/PathwayBrowser/#/R-GGA-1678923 TLR folding by chaperones GP96 and CNPY3 IEA Gallus gallus A0A1D5PPN9 R-GGA-1678944 https://reactome.org/PathwayBrowser/#/R-GGA-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex IEA Gallus gallus A0A1D5PPN9 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus A0A1D5PPN9 R-GGA-6790038 https://reactome.org/PathwayBrowser/#/R-GGA-6790038 Expression of HSP90B1 IEA Gallus gallus A0A1D5PPN9 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5PPP1 R-GGA-8982012 https://reactome.org/PathwayBrowser/#/R-GGA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Gallus gallus A0A1D5PPP1 R-GGA-8982019 https://reactome.org/PathwayBrowser/#/R-GGA-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Gallus gallus A0A1D5PPP1 R-GGA-8982020 https://reactome.org/PathwayBrowser/#/R-GGA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Gallus gallus A0A1D5PPP2 R-GGA-6788295 https://reactome.org/PathwayBrowser/#/R-GGA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Gallus gallus A0A1D5PPQ2 R-GGA-5334794 https://reactome.org/PathwayBrowser/#/R-GGA-5334794 FABPs bind LCFAs IEA Gallus gallus A0A1D5PPQ2 R-GGA-5422942 https://reactome.org/PathwayBrowser/#/R-GGA-5422942 RXRA:PPARD binds FABP5:atRA IEA Gallus gallus A0A1D5PPQ2 R-GGA-5622129 https://reactome.org/PathwayBrowser/#/R-GGA-5622129 FABP5 binds atRA IEA Gallus gallus A0A1D5PPQ2 R-GGA-5633256 https://reactome.org/PathwayBrowser/#/R-GGA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Gallus gallus A0A1D5PPQ2 R-GGA-5634100 https://reactome.org/PathwayBrowser/#/R-GGA-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Gallus gallus A0A1D5PPQ2 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PPQ2 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5PPT3 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PPV6 R-GGA-606287 https://reactome.org/PathwayBrowser/#/R-GGA-606287 RSF complex binds the centromere IEA Gallus gallus A0A1D5PPV6 R-GGA-606289 https://reactome.org/PathwayBrowser/#/R-GGA-606289 New CENPA-containing nucleosomes are deposited at the centromere IEA Gallus gallus A0A1D5PPV6 R-GGA-606326 https://reactome.org/PathwayBrowser/#/R-GGA-606326 HJURP:CENPA complex localizes to the centromere IEA Gallus gallus A0A1D5PPV6 R-GGA-9929884 https://reactome.org/PathwayBrowser/#/R-GGA-9929884 CCNA:CDK1 phosphorylates HJURP IEA Gallus gallus A0A1D5PPX6 R-GGA-888577 https://reactome.org/PathwayBrowser/#/R-GGA-888577 Synthesis of GABA by GAD2 IEA Gallus gallus A0A1D5PPZ1 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus A0A1D5PPZ1 R-GGA-9679787 https://reactome.org/PathwayBrowser/#/R-GGA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Gallus gallus A0A1D5PQ02 R-GGA-2176502 https://reactome.org/PathwayBrowser/#/R-GGA-2176502 NEDD4L ubiquitinates SMAD2/3 IEA Gallus gallus A0A1D5PQ02 R-GGA-2682349 https://reactome.org/PathwayBrowser/#/R-GGA-2682349 RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels IEA Gallus gallus A0A1D5PQ02 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PQ02 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PQ02 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PQ02 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PQ17 R-GGA-5691108 https://reactome.org/PathwayBrowser/#/R-GGA-5691108 SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 IEA Gallus gallus A0A1D5PQ44 R-GGA-201712 https://reactome.org/PathwayBrowser/#/R-GGA-201712 Beta-catenin:TCF associates with BCL9 and PYGO IEA Gallus gallus A0A1D5PQ44 R-GGA-3364026 https://reactome.org/PathwayBrowser/#/R-GGA-3364026 SET1 complex trimethylates H3K4 at the MYC gene IEA Gallus gallus A0A1D5PQ46 R-GGA-532603 https://reactome.org/PathwayBrowser/#/R-GGA-532603 Nephrin mediated activation of N-WASP IEA Gallus gallus A0A1D5PQ50 R-GGA-446191 https://reactome.org/PathwayBrowser/#/R-GGA-446191 Addition of N-acetyl-D-glucosamine to Dolichyl phosphate IEA Gallus gallus A0A1D5PQ51 R-GGA-165026 https://reactome.org/PathwayBrowser/#/R-GGA-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Gallus gallus A0A1D5PQ51 R-GGA-549297 https://reactome.org/PathwayBrowser/#/R-GGA-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Gallus gallus A0A1D5PQ57 R-GGA-1855221 https://reactome.org/PathwayBrowser/#/R-GGA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Gallus gallus A0A1D5PQ64 R-GGA-1676109 https://reactome.org/PathwayBrowser/#/R-GGA-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Gallus gallus A0A1D5PQ65 R-GGA-6805546 https://reactome.org/PathwayBrowser/#/R-GGA-6805546 Keratin type I binds keratin type II IEA Gallus gallus A0A1D5PQ65 R-GGA-6805573 https://reactome.org/PathwayBrowser/#/R-GGA-6805573 Keratin type I/type II heterodimers form tetramers IEA Gallus gallus A0A1D5PQ65 R-GGA-6806610 https://reactome.org/PathwayBrowser/#/R-GGA-6806610 Keratin filament formation IEA Gallus gallus A0A1D5PQ65 R-GGA-6806613 https://reactome.org/PathwayBrowser/#/R-GGA-6806613 Keratin tetramers bind to form unit length filaments IEA Gallus gallus A0A1D5PQ65 R-GGA-6806629 https://reactome.org/PathwayBrowser/#/R-GGA-6806629 Formation of tonofilament bundles IEA Gallus gallus A0A1D5PQ65 R-GGA-6809393 https://reactome.org/PathwayBrowser/#/R-GGA-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Gallus gallus A0A1D5PQ65 R-GGA-6810357 https://reactome.org/PathwayBrowser/#/R-GGA-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Gallus gallus A0A1D5PQ72 R-GGA-375140 https://reactome.org/PathwayBrowser/#/R-GGA-375140 CDO binds promyogenic cadherins IEA Gallus gallus A0A1D5PQ72 R-GGA-419001 https://reactome.org/PathwayBrowser/#/R-GGA-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Gallus gallus A0A1D5PQ72 R-GGA-419002 https://reactome.org/PathwayBrowser/#/R-GGA-419002 Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin IEA Gallus gallus A0A1D5PQ72 R-GGA-448958 https://reactome.org/PathwayBrowser/#/R-GGA-448958 Nuclear translocation of p38 MAPK IEA Gallus gallus A0A1D5PQ74 R-GGA-429860 https://reactome.org/PathwayBrowser/#/R-GGA-429860 DCP1-DCP2 complex decaps mRNA IEA Gallus gallus A0A1D5PQ74 R-GGA-450488 https://reactome.org/PathwayBrowser/#/R-GGA-450488 BRF1 Complex recruits RNA degradation activities IEA Gallus gallus A0A1D5PQ89 R-GGA-6786245 https://reactome.org/PathwayBrowser/#/R-GGA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Gallus gallus A0A1D5PQ92 R-GGA-6805546 https://reactome.org/PathwayBrowser/#/R-GGA-6805546 Keratin type I binds keratin type II IEA Gallus gallus A0A1D5PQ92 R-GGA-6805573 https://reactome.org/PathwayBrowser/#/R-GGA-6805573 Keratin type I/type II heterodimers form tetramers IEA Gallus gallus A0A1D5PQ92 R-GGA-6806610 https://reactome.org/PathwayBrowser/#/R-GGA-6806610 Keratin filament formation IEA Gallus gallus A0A1D5PQ92 R-GGA-6806613 https://reactome.org/PathwayBrowser/#/R-GGA-6806613 Keratin tetramers bind to form unit length filaments IEA Gallus gallus A0A1D5PQ92 R-GGA-6806629 https://reactome.org/PathwayBrowser/#/R-GGA-6806629 Formation of tonofilament bundles IEA Gallus gallus A0A1D5PQ92 R-GGA-6809393 https://reactome.org/PathwayBrowser/#/R-GGA-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Gallus gallus A0A1D5PQ92 R-GGA-6810357 https://reactome.org/PathwayBrowser/#/R-GGA-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Gallus gallus A0A1D5PQ97 R-GGA-420592 https://reactome.org/PathwayBrowser/#/R-GGA-420592 Transhomodimerization of Nectin-like (Necl) proteins IEA Gallus gallus A0A1D5PQB2 R-GGA-1008248 https://reactome.org/PathwayBrowser/#/R-GGA-1008248 Adenylate Kinase 3 is a GTP-AMP phosphotransferase IEA Gallus gallus A0A1D5PQB9 R-GGA-5577050 https://reactome.org/PathwayBrowser/#/R-GGA-5577050 AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region IEA Gallus gallus A0A1D5PQB9 R-GGA-5577237 https://reactome.org/PathwayBrowser/#/R-GGA-5577237 KCNH2:KCNE transport K+ from cytosol to extracellular region IEA Gallus gallus A0A1D5PQB9 R-GGA-9613264 https://reactome.org/PathwayBrowser/#/R-GGA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Gallus gallus A0A1D5PQC5 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus A0A1D5PQC5 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus A0A1D5PQC5 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus A0A1D5PQC5 R-GGA-6799202 https://reactome.org/PathwayBrowser/#/R-GGA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Gallus gallus A0A1D5PQD3 R-GGA-5678327 https://reactome.org/PathwayBrowser/#/R-GGA-5678327 MIOX oxidises Ins to GlcA IEA Gallus gallus A0A1D5PQD7 R-GGA-9639287 https://reactome.org/PathwayBrowser/#/R-GGA-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Gallus gallus A0A1D5PQD7 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus A0A1D5PQD7 R-GGA-9640237 https://reactome.org/PathwayBrowser/#/R-GGA-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Gallus gallus A0A1D5PQD7 R-GGA-9640254 https://reactome.org/PathwayBrowser/#/R-GGA-9640254 BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 IEA Gallus gallus A0A1D5PQD7 R-GGA-9657619 https://reactome.org/PathwayBrowser/#/R-GGA-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 IEA Gallus gallus A0A1D5PQE4 R-GGA-5669035 https://reactome.org/PathwayBrowser/#/R-GGA-5669035 TNFSF11 binds TNFRSF11A, B IEA Gallus gallus A0A1D5PQE8 R-GGA-114552 https://reactome.org/PathwayBrowser/#/R-GGA-114552 Thrombin-activated PARs activate G12/13 IEA Gallus gallus A0A1D5PQE8 R-GGA-397891 https://reactome.org/PathwayBrowser/#/R-GGA-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Gallus gallus A0A1D5PQE8 R-GGA-398184 https://reactome.org/PathwayBrowser/#/R-GGA-398184 LARG activation by G alpha 12/13 IEA Gallus gallus A0A1D5PQE8 R-GGA-398185 https://reactome.org/PathwayBrowser/#/R-GGA-398185 LARG binds plexin B1 IEA Gallus gallus A0A1D5PQE8 R-GGA-418574 https://reactome.org/PathwayBrowser/#/R-GGA-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Gallus gallus A0A1D5PQE8 R-GGA-428909 https://reactome.org/PathwayBrowser/#/R-GGA-428909 Activated TP receptor binds G-protein G13 IEA Gallus gallus A0A1D5PQE8 R-GGA-428917 https://reactome.org/PathwayBrowser/#/R-GGA-428917 G13 activation by TP receptor IEA Gallus gallus A0A1D5PQE8 R-GGA-428918 https://reactome.org/PathwayBrowser/#/R-GGA-428918 Dissociation of the TP:G13 complex IEA Gallus gallus A0A1D5PQE8 R-GGA-751019 https://reactome.org/PathwayBrowser/#/R-GGA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Gallus gallus A0A1D5PQE8 R-GGA-751027 https://reactome.org/PathwayBrowser/#/R-GGA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Gallus gallus A0A1D5PQE8 R-GGA-751029 https://reactome.org/PathwayBrowser/#/R-GGA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Gallus gallus A0A1D5PQE8 R-GGA-751039 https://reactome.org/PathwayBrowser/#/R-GGA-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Gallus gallus A0A1D5PQE8 R-GGA-9013143 https://reactome.org/PathwayBrowser/#/R-GGA-9013143 RAC1 GEFs activate RAC1 IEA Gallus gallus A0A1D5PQE8 R-GGA-9013159 https://reactome.org/PathwayBrowser/#/R-GGA-9013159 CDC42 GEFs activate CDC42 IEA Gallus gallus A0A1D5PQF9 R-GGA-6807877 https://reactome.org/PathwayBrowser/#/R-GGA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Gallus gallus A0A1D5PQF9 R-GGA-6811417 https://reactome.org/PathwayBrowser/#/R-GGA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Gallus gallus A0A1D5PQF9 R-GGA-6811418 https://reactome.org/PathwayBrowser/#/R-GGA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Gallus gallus A0A1D5PQG4 R-GGA-8938930 https://reactome.org/PathwayBrowser/#/R-GGA-8938930 RUNX1 binds ELF2 IEA Gallus gallus A0A1D5PQI1 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PQI1 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1D5PQJ2 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus A0A1D5PQJ2 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus A0A1D5PQJ2 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus A0A1D5PQJ6 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5PQJ6 R-GGA-9609921 https://reactome.org/PathwayBrowser/#/R-GGA-9609921 SGTA binds Tail-anchored protein IEA Gallus gallus A0A1D5PQN5 R-GGA-6805546 https://reactome.org/PathwayBrowser/#/R-GGA-6805546 Keratin type I binds keratin type II IEA Gallus gallus A0A1D5PQN5 R-GGA-6805573 https://reactome.org/PathwayBrowser/#/R-GGA-6805573 Keratin type I/type II heterodimers form tetramers IEA Gallus gallus A0A1D5PQN5 R-GGA-6806610 https://reactome.org/PathwayBrowser/#/R-GGA-6806610 Keratin filament formation IEA Gallus gallus A0A1D5PQN5 R-GGA-6806613 https://reactome.org/PathwayBrowser/#/R-GGA-6806613 Keratin tetramers bind to form unit length filaments IEA Gallus gallus A0A1D5PQN5 R-GGA-6806629 https://reactome.org/PathwayBrowser/#/R-GGA-6806629 Formation of tonofilament bundles IEA Gallus gallus A0A1D5PQN5 R-GGA-6809393 https://reactome.org/PathwayBrowser/#/R-GGA-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Gallus gallus A0A1D5PQN5 R-GGA-6810357 https://reactome.org/PathwayBrowser/#/R-GGA-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Gallus gallus A0A1D5PQP3 R-GGA-1253282 https://reactome.org/PathwayBrowser/#/R-GGA-1253282 ERBB4 ubiquitination by WWP1/ITCH IEA Gallus gallus A0A1D5PQP3 R-GGA-1253300 https://reactome.org/PathwayBrowser/#/R-GGA-1253300 ERBB4 binds WWP1/ITCH ubiquitin ligases IEA Gallus gallus A0A1D5PQP3 R-GGA-1912357 https://reactome.org/PathwayBrowser/#/R-GGA-1912357 ITCH ubiquitinates DTX IEA Gallus gallus A0A1D5PQP3 R-GGA-1980125 https://reactome.org/PathwayBrowser/#/R-GGA-1980125 ITCH binds DTX IEA Gallus gallus A0A1D5PQP3 R-GGA-5610735 https://reactome.org/PathwayBrowser/#/R-GGA-5610735 NUMB binds ITCH IEA Gallus gallus A0A1D5PQP3 R-GGA-5610737 https://reactome.org/PathwayBrowser/#/R-GGA-5610737 NUMB:ITCH bind and ubiquitnate GLI1 IEA Gallus gallus A0A1D5PQP3 R-GGA-5610760 https://reactome.org/PathwayBrowser/#/R-GGA-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Gallus gallus A0A1D5PQP3 R-GGA-5635861 https://reactome.org/PathwayBrowser/#/R-GGA-5635861 NUMB:ITCH binds GLI1 IEA Gallus gallus A0A1D5PQP3 R-GGA-5635864 https://reactome.org/PathwayBrowser/#/R-GGA-5635864 NUMB:ITCH ubiquitinates GLI1 IEA Gallus gallus A0A1D5PQP3 R-GGA-5635868 https://reactome.org/PathwayBrowser/#/R-GGA-5635868 ub-GLI is degraded by the proteasome IEA Gallus gallus A0A1D5PQP3 R-GGA-8956684 https://reactome.org/PathwayBrowser/#/R-GGA-8956684 ITCH polyubiquitinates TP73 IEA Gallus gallus A0A1D5PQP3 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PQP3 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PQP3 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PQP3 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PQP8 R-GGA-216068 https://reactome.org/PathwayBrowser/#/R-GGA-216068 Interaction of integrin alpha9beta1 with Tenascin-C IEA Gallus gallus A0A1D5PQP8 R-GGA-265424 https://reactome.org/PathwayBrowser/#/R-GGA-265424 SPP1 (osteopontin) binds integrin alpha5beta1, alpha9beta1 IEA Gallus gallus A0A1D5PQP8 R-GGA-2681667 https://reactome.org/PathwayBrowser/#/R-GGA-2681667 TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 IEA Gallus gallus A0A1D5PQQ5 R-GGA-430028 https://reactome.org/PathwayBrowser/#/R-GGA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Gallus gallus A0A1D5PQV0 R-GGA-5690873 https://reactome.org/PathwayBrowser/#/R-GGA-5690873 ACO1 binds 4Fe-4S IEA Gallus gallus A0A1D5PQV0 R-GGA-5690911 https://reactome.org/PathwayBrowser/#/R-GGA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT IEA Gallus gallus A0A1D5PQV3 R-GGA-5694018 https://reactome.org/PathwayBrowser/#/R-GGA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Gallus gallus A0A1D5PQV3 R-GGA-6792572 https://reactome.org/PathwayBrowser/#/R-GGA-6792572 LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST IEA Gallus gallus A0A1D5PQV3 R-GGA-71401 https://reactome.org/PathwayBrowser/#/R-GGA-71401 OGDH dimer decarboxylates 2-OG IEA Gallus gallus A0A1D5PQV3 R-GGA-9853499 https://reactome.org/PathwayBrowser/#/R-GGA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus A0A1D5PQV3 R-GGA-9853512 https://reactome.org/PathwayBrowser/#/R-GGA-9853512 DLST transfers succinyl to CoA IEA Gallus gallus A0A1D5PQV3 R-GGA-9858321 https://reactome.org/PathwayBrowser/#/R-GGA-9858321 DHTKD1 dimer decarboxylates 2-OA IEA Gallus gallus A0A1D5PQV3 R-GGA-9858589 https://reactome.org/PathwayBrowser/#/R-GGA-9858589 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus A0A1D5PQV3 R-GGA-9858590 https://reactome.org/PathwayBrowser/#/R-GGA-9858590 DLST transfers glutaryl to CoA IEA Gallus gallus A0A1D5PQW2 R-GGA-446201 https://reactome.org/PathwayBrowser/#/R-GGA-446201 PMM1,2 isomerise Man6P to Man1P IEA Gallus gallus A0A1D5PQX0 R-GGA-199839 https://reactome.org/PathwayBrowser/#/R-GGA-199839 AKT can phosphorylate RSK IEA Gallus gallus A0A1D5PQY0 R-GGA-8981657 https://reactome.org/PathwayBrowser/#/R-GGA-8981657 IL34 dimer binds PTPRZ1 IEA Gallus gallus A0A1D5PQY0 R-GGA-9700120 https://reactome.org/PathwayBrowser/#/R-GGA-9700120 PTN and MDK bind to PTPRZ IEA Gallus gallus A0A1D5PQY0 R-GGA-9700121 https://reactome.org/PathwayBrowser/#/R-GGA-9700121 (PTN,MDK):PTPRZ oligomerizes IEA Gallus gallus A0A1D5PQY0 R-GGA-9700200 https://reactome.org/PathwayBrowser/#/R-GGA-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Gallus gallus A0A1D5PQY8 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus A0A1D5PQY8 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1D5PQY8 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1D5PQY8 R-GGA-9018778 https://reactome.org/PathwayBrowser/#/R-GGA-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Gallus gallus A0A1D5PQY8 R-GGA-9018787 https://reactome.org/PathwayBrowser/#/R-GGA-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Gallus gallus A0A1D5PQY8 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5PQZ6 R-GGA-5577050 https://reactome.org/PathwayBrowser/#/R-GGA-5577050 AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region IEA Gallus gallus A0A1D5PQZ6 R-GGA-5577237 https://reactome.org/PathwayBrowser/#/R-GGA-5577237 KCNH2:KCNE transport K+ from cytosol to extracellular region IEA Gallus gallus A0A1D5PQZ6 R-GGA-9613264 https://reactome.org/PathwayBrowser/#/R-GGA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Gallus gallus A0A1D5PR16 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus A0A1D5PR16 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus A0A1D5PR16 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus A0A1D5PR16 R-GGA-1981120 https://reactome.org/PathwayBrowser/#/R-GGA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Gallus gallus A0A1D5PR16 R-GGA-2002460 https://reactome.org/PathwayBrowser/#/R-GGA-2002460 P4HB binds Collagen chains IEA Gallus gallus A0A1D5PR16 R-GGA-2152276 https://reactome.org/PathwayBrowser/#/R-GGA-2152276 Secretion of transmembrane collagens IEA Gallus gallus A0A1D5PR16 R-GGA-2471842 https://reactome.org/PathwayBrowser/#/R-GGA-2471842 Collagen type XXV ectomain shedding IEA Gallus gallus A0A1D5PR16 R-GGA-8944250 https://reactome.org/PathwayBrowser/#/R-GGA-8944250 Association of procollagen type XXV IEA Gallus gallus A0A1D5PR16 R-GGA-8948228 https://reactome.org/PathwayBrowser/#/R-GGA-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Gallus gallus A0A1D5PR16 R-GGA-8948231 https://reactome.org/PathwayBrowser/#/R-GGA-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Gallus gallus A0A1D5PR16 R-GGA-8948232 https://reactome.org/PathwayBrowser/#/R-GGA-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Gallus gallus A0A1D5PR16 R-GGA-8948234 https://reactome.org/PathwayBrowser/#/R-GGA-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Gallus gallus A0A1D5PR25 R-GGA-1602466 https://reactome.org/PathwayBrowser/#/R-GGA-1602466 Activation of MT-MMPs by FURIN IEA Gallus gallus A0A1D5PR25 R-GGA-1605825 https://reactome.org/PathwayBrowser/#/R-GGA-1605825 MT-MMPs are sorted to the plasma membrane IEA Gallus gallus A0A1D5PR25 R-GGA-2473584 https://reactome.org/PathwayBrowser/#/R-GGA-2473584 Collagen type III degradation by MMP15 IEA Gallus gallus A0A1D5PR25 R-GGA-2473594 https://reactome.org/PathwayBrowser/#/R-GGA-2473594 Collagen type II degradation by MMP15 IEA Gallus gallus A0A1D5PR25 R-GGA-2473596 https://reactome.org/PathwayBrowser/#/R-GGA-2473596 Collagen type I degradation by MMP15 IEA Gallus gallus A0A1D5PR30 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A1D5PR30 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A1D5PR30 R-GGA-141423 https://reactome.org/PathwayBrowser/#/R-GGA-141423 Binding of the MCC complex to the APC/C complex IEA Gallus gallus A0A1D5PR30 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A1D5PR30 R-GGA-141437 https://reactome.org/PathwayBrowser/#/R-GGA-141437 Formation of the MCC complex IEA Gallus gallus A0A1D5PR30 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A1D5PR30 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5PR30 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5PR30 R-GGA-174104 https://reactome.org/PathwayBrowser/#/R-GGA-174104 Ubiquitination of Cyclin A by APC/C:Cdc20 complex IEA Gallus gallus A0A1D5PR30 R-GGA-174171 https://reactome.org/PathwayBrowser/#/R-GGA-174171 Association of Cyclin A with the APC/C IEA Gallus gallus A0A1D5PR30 R-GGA-174238 https://reactome.org/PathwayBrowser/#/R-GGA-174238 Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 IEA Gallus gallus A0A1D5PR30 R-GGA-174255 https://reactome.org/PathwayBrowser/#/R-GGA-174255 Degradation multiubiquitinated Cyclin A IEA Gallus gallus A0A1D5PR30 R-GGA-179410 https://reactome.org/PathwayBrowser/#/R-GGA-179410 Association of Nek2A with MCC:APC/C IEA Gallus gallus A0A1D5PR30 R-GGA-179417 https://reactome.org/PathwayBrowser/#/R-GGA-179417 Multiubiquitination of Nek2A IEA Gallus gallus A0A1D5PR30 R-GGA-179421 https://reactome.org/PathwayBrowser/#/R-GGA-179421 Degradation of multiubiquitinated Nek2A IEA Gallus gallus A0A1D5PR30 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5PR30 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5PR30 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5PR30 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A1D5PR30 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1D5PR38 R-GGA-8952618 https://reactome.org/PathwayBrowser/#/R-GGA-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PR38 R-GGA-8952620 https://reactome.org/PathwayBrowser/#/R-GGA-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PR38 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5PR38 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5PR38 R-GGA-8956200 https://reactome.org/PathwayBrowser/#/R-GGA-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PR38 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PR38 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PR38 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PR38 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PR69 R-GGA-6788912 https://reactome.org/PathwayBrowser/#/R-GGA-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Gallus gallus A0A1D5PR76 R-GGA-202214 https://reactome.org/PathwayBrowser/#/R-GGA-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Gallus gallus A0A1D5PR76 R-GGA-202233 https://reactome.org/PathwayBrowser/#/R-GGA-202233 Inactivation of Lck by Csk IEA Gallus gallus A0A1D5PR76 R-GGA-373746 https://reactome.org/PathwayBrowser/#/R-GGA-373746 SEMA4D interacts with CD45 IEA Gallus gallus A0A1D5PR76 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PR78 R-GGA-1226094 https://reactome.org/PathwayBrowser/#/R-GGA-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Gallus gallus A0A1D5PR78 R-GGA-1226095 https://reactome.org/PathwayBrowser/#/R-GGA-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Gallus gallus A0A1D5PR78 R-GGA-1227670 https://reactome.org/PathwayBrowser/#/R-GGA-1227670 Recruitment of HDAC1 by p130 (RBL2) IEA Gallus gallus A0A1D5PR78 R-GGA-1227671 https://reactome.org/PathwayBrowser/#/R-GGA-1227671 Recruitment of HDAC1 by p107 (RBL1) IEA Gallus gallus A0A1D5PR78 R-GGA-1362261 https://reactome.org/PathwayBrowser/#/R-GGA-1362261 p130 (RBL2) associates with MuvB to form DREAM complex IEA Gallus gallus A0A1D5PR78 R-GGA-1363303 https://reactome.org/PathwayBrowser/#/R-GGA-1363303 p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 IEA Gallus gallus A0A1D5PR78 R-GGA-1363311 https://reactome.org/PathwayBrowser/#/R-GGA-1363311 p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 IEA Gallus gallus A0A1D5PR78 R-GGA-8954056 https://reactome.org/PathwayBrowser/#/R-GGA-8954056 E2F6 binds TFDP2 IEA Gallus gallus A0A1D5PR78 R-GGA-8954082 https://reactome.org/PathwayBrowser/#/R-GGA-8954082 E2F6 binds the PRC1 complex IEA Gallus gallus A0A1D5PR78 R-GGA-9018017 https://reactome.org/PathwayBrowser/#/R-GGA-9018017 RB1 binds and inhibits E2F1/2/3:DP1/2 complexes IEA Gallus gallus A0A1D5PR81 R-GGA-8952044 https://reactome.org/PathwayBrowser/#/R-GGA-8952044 AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PR81 R-GGA-8952618 https://reactome.org/PathwayBrowser/#/R-GGA-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PR81 R-GGA-8952620 https://reactome.org/PathwayBrowser/#/R-GGA-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PR81 R-GGA-8952626 https://reactome.org/PathwayBrowser/#/R-GGA-8952626 AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PR81 R-GGA-8952630 https://reactome.org/PathwayBrowser/#/R-GGA-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PR81 R-GGA-8952631 https://reactome.org/PathwayBrowser/#/R-GGA-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PR81 R-GGA-8952638 https://reactome.org/PathwayBrowser/#/R-GGA-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PR81 R-GGA-8952639 https://reactome.org/PathwayBrowser/#/R-GGA-8952639 NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PR81 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5PR81 R-GGA-8956045 https://reactome.org/PathwayBrowser/#/R-GGA-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PR81 R-GGA-8956099 https://reactome.org/PathwayBrowser/#/R-GGA-8956099 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 IEA Gallus gallus A0A1D5PR81 R-GGA-8956103 https://reactome.org/PathwayBrowser/#/R-GGA-8956103 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha IEA Gallus gallus A0A1D5PR81 R-GGA-8956106 https://reactome.org/PathwayBrowser/#/R-GGA-8956106 VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha IEA Gallus gallus A0A1D5PR81 R-GGA-8956200 https://reactome.org/PathwayBrowser/#/R-GGA-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PR81 R-GGA-9755303 https://reactome.org/PathwayBrowser/#/R-GGA-9755303 26S proteasome degrades HIFalpha IEA Gallus gallus A0A1D5PRA3 R-GGA-422051 https://reactome.org/PathwayBrowser/#/R-GGA-422051 Cleavage of the signal peptide of Preproghrelin IEA Gallus gallus A0A1D5PRA8 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PRA8 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PRA8 R-GGA-70420 https://reactome.org/PathwayBrowser/#/R-GGA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Gallus gallus A0A1D5PRB3 R-GGA-909718 https://reactome.org/PathwayBrowser/#/R-GGA-909718 Formation of p-STAT1 homodimer IEA Gallus gallus A0A1D5PRB3 R-GGA-909719 https://reactome.org/PathwayBrowser/#/R-GGA-909719 Recruitment of STAT2 to p-IFNAR1 IEA Gallus gallus A0A1D5PRB3 R-GGA-909722 https://reactome.org/PathwayBrowser/#/R-GGA-909722 Release of p-STAT2:p-STAT1 dimer IEA Gallus gallus A0A1D5PRB3 R-GGA-909724 https://reactome.org/PathwayBrowser/#/R-GGA-909724 Recruitment of IFNAR1 IEA Gallus gallus A0A1D5PRB3 R-GGA-909729 https://reactome.org/PathwayBrowser/#/R-GGA-909729 Activation of JAK kinases IEA Gallus gallus A0A1D5PRB3 R-GGA-909730 https://reactome.org/PathwayBrowser/#/R-GGA-909730 Phosphorylation of INFAR1 by TYK2 IEA Gallus gallus A0A1D5PRB3 R-GGA-909732 https://reactome.org/PathwayBrowser/#/R-GGA-909732 Phosphorylation of STAT2 IEA Gallus gallus A0A1D5PRB3 R-GGA-9678737 https://reactome.org/PathwayBrowser/#/R-GGA-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Gallus gallus A0A1D5PRB3 R-GGA-997309 https://reactome.org/PathwayBrowser/#/R-GGA-997309 Dephosphorylation of STAT1 by SHP2 IEA Gallus gallus A0A1D5PRB3 R-GGA-997311 https://reactome.org/PathwayBrowser/#/R-GGA-997311 Dephosphorylation of TYK2 by PTP1B IEA Gallus gallus A0A1D5PRB3 R-GGA-997314 https://reactome.org/PathwayBrowser/#/R-GGA-997314 Dephosphorylation of JAK1 by SHP1 IEA Gallus gallus A0A1D5PRB6 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus A0A1D5PRB6 R-GGA-6799178 https://reactome.org/PathwayBrowser/#/R-GGA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Gallus gallus A0A1D5PRB6 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus A0A1D5PRB6 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus A0A1D5PRB6 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus A0A1D5PRB6 R-GGA-6799202 https://reactome.org/PathwayBrowser/#/R-GGA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Gallus gallus A0A1D5PRD6 R-GGA-1592387 https://reactome.org/PathwayBrowser/#/R-GGA-1592387 Fibulin binds elastic fibres IEA Gallus gallus A0A1D5PRD6 R-GGA-2129357 https://reactome.org/PathwayBrowser/#/R-GGA-2129357 Fibrillin C-terminal processing IEA Gallus gallus A0A1D5PRD6 R-GGA-2129362 https://reactome.org/PathwayBrowser/#/R-GGA-2129362 Fibrillin microfibril assembly IEA Gallus gallus A0A1D5PRD6 R-GGA-2129375 https://reactome.org/PathwayBrowser/#/R-GGA-2129375 Elastin cross-linking by lysyl oxidase IEA Gallus gallus A0A1D5PRD6 R-GGA-2129385 https://reactome.org/PathwayBrowser/#/R-GGA-2129385 MFAP2, MFAP5 bind microfibrils IEA Gallus gallus A0A1D5PRD6 R-GGA-2161282 https://reactome.org/PathwayBrowser/#/R-GGA-2161282 Elastic fibres bind associated proteins IEA Gallus gallus A0A1D5PRD6 R-GGA-2396399 https://reactome.org/PathwayBrowser/#/R-GGA-2396399 Fibrillins bind BMPs IEA Gallus gallus A0A1D5PRD6 R-GGA-2485148 https://reactome.org/PathwayBrowser/#/R-GGA-2485148 Fibrillin 1, 2,(3) degradation by MMP2, 9, 12 and 13 IEA Gallus gallus A0A1D5PRF9 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1D5PRF9 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1D5PRF9 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus A0A1D5PRF9 R-GGA-9013022 https://reactome.org/PathwayBrowser/#/R-GGA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Gallus gallus A0A1D5PRF9 R-GGA-9013111 https://reactome.org/PathwayBrowser/#/R-GGA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Gallus gallus A0A1D5PRF9 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus A0A1D5PRF9 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus A0A1D5PRF9 R-GGA-9013437 https://reactome.org/PathwayBrowser/#/R-GGA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Gallus gallus A0A1D5PRF9 R-GGA-9014295 https://reactome.org/PathwayBrowser/#/R-GGA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Gallus gallus A0A1D5PRF9 R-GGA-9018806 https://reactome.org/PathwayBrowser/#/R-GGA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Gallus gallus A0A1D5PRF9 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus A0A1D5PRF9 R-GGA-984648 https://reactome.org/PathwayBrowser/#/R-GGA-984648 Kinesin-6 and RACGAP1 form the heterotetrameric complex centralspindlin IEA Gallus gallus A0A1D5PRH4 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus A0A1D5PRH4 R-GGA-3928612 https://reactome.org/PathwayBrowser/#/R-GGA-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5PRH4 R-GGA-3928617 https://reactome.org/PathwayBrowser/#/R-GGA-3928617 EPHB2 binds KALRN IEA Gallus gallus A0A1D5PRH4 R-GGA-400586 https://reactome.org/PathwayBrowser/#/R-GGA-400586 G alpha (q) binds to Trio family RhoGEFs IEA Gallus gallus A0A1D5PRH4 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus A0A1D5PRH4 R-GGA-5692768 https://reactome.org/PathwayBrowser/#/R-GGA-5692768 MAPKAPK5 phosphorylates KALRN IEA Gallus gallus A0A1D5PRH4 R-GGA-5692781 https://reactome.org/PathwayBrowser/#/R-GGA-5692781 p-S189 MAPK6:p-T182 MAPKAPK5 bind KALRN IEA Gallus gallus A0A1D5PRH4 R-GGA-8980691 https://reactome.org/PathwayBrowser/#/R-GGA-8980691 RHOA GEFs activate RHOA IEA Gallus gallus A0A1D5PRH4 R-GGA-9013143 https://reactome.org/PathwayBrowser/#/R-GGA-9013143 RAC1 GEFs activate RAC1 IEA Gallus gallus A0A1D5PRH4 R-GGA-9014433 https://reactome.org/PathwayBrowser/#/R-GGA-9014433 RHOG GEFs activate RHOG IEA Gallus gallus A0A1D5PRI6 R-GGA-4332236 https://reactome.org/PathwayBrowser/#/R-GGA-4332236 CBL neddylates TGFBR2 IEA Gallus gallus A0A1D5PRI6 R-GGA-5690808 https://reactome.org/PathwayBrowser/#/R-GGA-5690808 UCHL3, SENP8 cleave NEDD8 IEA Gallus gallus A0A1D5PRI6 R-GGA-5691108 https://reactome.org/PathwayBrowser/#/R-GGA-5691108 SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 IEA Gallus gallus A0A1D5PRI6 R-GGA-5691176 https://reactome.org/PathwayBrowser/#/R-GGA-5691176 NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) IEA Gallus gallus A0A1D5PRI6 R-GGA-8863723 https://reactome.org/PathwayBrowser/#/R-GGA-8863723 COP9 and TOR1 deneddylate STON2 IEA Gallus gallus A0A1D5PRI6 R-GGA-8863727 https://reactome.org/PathwayBrowser/#/R-GGA-8863727 STON2 is neddylated IEA Gallus gallus A0A1D5PRI6 R-GGA-8951644 https://reactome.org/PathwayBrowser/#/R-GGA-8951644 Release of mature NEDD8 IEA Gallus gallus A0A1D5PRI6 R-GGA-8951648 https://reactome.org/PathwayBrowser/#/R-GGA-8951648 NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 IEA Gallus gallus A0A1D5PRI6 R-GGA-8951656 https://reactome.org/PathwayBrowser/#/R-GGA-8951656 NEDD8-UBA3:NAE1 binds a second NEDD8 IEA Gallus gallus A0A1D5PRI6 R-GGA-8951661 https://reactome.org/PathwayBrowser/#/R-GGA-8951661 Transfer of NEDD8 to AcM-UBE2M IEA Gallus gallus A0A1D5PRI6 R-GGA-8951751 https://reactome.org/PathwayBrowser/#/R-GGA-8951751 Doubly neddylated UBA3:NAE1 binds AcM-UBE2M IEA Gallus gallus A0A1D5PRI6 R-GGA-8951764 https://reactome.org/PathwayBrowser/#/R-GGA-8951764 Transfer of NEDD8 to AcM-UBE2F IEA Gallus gallus A0A1D5PRI6 R-GGA-8951766 https://reactome.org/PathwayBrowser/#/R-GGA-8951766 Doubly neddylated UBA3:NAE1 binds AcM-UBE2F IEA Gallus gallus A0A1D5PRI6 R-GGA-8952044 https://reactome.org/PathwayBrowser/#/R-GGA-8952044 AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PRI6 R-GGA-8952618 https://reactome.org/PathwayBrowser/#/R-GGA-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PRI6 R-GGA-8952620 https://reactome.org/PathwayBrowser/#/R-GGA-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PRI6 R-GGA-8952626 https://reactome.org/PathwayBrowser/#/R-GGA-8952626 AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PRI6 R-GGA-8952630 https://reactome.org/PathwayBrowser/#/R-GGA-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PRI6 R-GGA-8952631 https://reactome.org/PathwayBrowser/#/R-GGA-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PRI6 R-GGA-8952638 https://reactome.org/PathwayBrowser/#/R-GGA-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PRI6 R-GGA-8952639 https://reactome.org/PathwayBrowser/#/R-GGA-8952639 NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PRI6 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5PRI6 R-GGA-8956045 https://reactome.org/PathwayBrowser/#/R-GGA-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PRI6 R-GGA-8956140 https://reactome.org/PathwayBrowser/#/R-GGA-8956140 NEDD8 and UBD bind NUB1 and the 26S proteasome IEA Gallus gallus A0A1D5PRI6 R-GGA-8956184 https://reactome.org/PathwayBrowser/#/R-GGA-8956184 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates IEA Gallus gallus A0A1D5PRJ4 R-GGA-5632732 https://reactome.org/PathwayBrowser/#/R-GGA-5632732 p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 IEA Gallus gallus A0A1D5PRJ4 R-GGA-5632738 https://reactome.org/PathwayBrowser/#/R-GGA-5632738 DDIT4 binds 14-3-3 dimer IEA Gallus gallus A0A1D5PRJ9 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5PRJ9 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1D5PRJ9 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1D5PRK3 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5PRK3 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5PRK3 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5PRK3 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5PRK3 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5PRL0 R-GGA-6807224 https://reactome.org/PathwayBrowser/#/R-GGA-6807224 Furin cleaves pro-BGLAP to BGLAP IEA Gallus gallus A0A1D5PRL0 R-GGA-6807229 https://reactome.org/PathwayBrowser/#/R-GGA-6807229 Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus IEA Gallus gallus A0A1D5PRL3 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus A0A1D5PRM3 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5PRM3 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5PRM3 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5PRM3 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5PRM3 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5PRN3 R-GGA-939763 https://reactome.org/PathwayBrowser/#/R-GGA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Gallus gallus A0A1D5PRN3 R-GGA-947591 https://reactome.org/PathwayBrowser/#/R-GGA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Gallus gallus A0A1D5PRP8 R-GGA-9677050 https://reactome.org/PathwayBrowser/#/R-GGA-9677050 Formation of the GCN5-ATAC complex IEA Gallus gallus A0A1D5PRP8 R-GGA-9677051 https://reactome.org/PathwayBrowser/#/R-GGA-9677051 Formation of the PCAF-ATAC complex IEA Gallus gallus A0A1D5PRP9 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5PRQ3 R-GGA-9012000 https://reactome.org/PathwayBrowser/#/R-GGA-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Gallus gallus A0A1D5PRZ0 R-GGA-8854222 https://reactome.org/PathwayBrowser/#/R-GGA-8854222 TBC1D3 associates with RAB5 IEA Gallus gallus A0A1D5PRZ3 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1D5PRZ3 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus A0A1D5PRZ3 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1D5PRZ3 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1D5PRZ3 R-GGA-751019 https://reactome.org/PathwayBrowser/#/R-GGA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Gallus gallus A0A1D5PRZ3 R-GGA-751027 https://reactome.org/PathwayBrowser/#/R-GGA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Gallus gallus A0A1D5PRZ3 R-GGA-751029 https://reactome.org/PathwayBrowser/#/R-GGA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Gallus gallus A0A1D5PRZ3 R-GGA-9617370 https://reactome.org/PathwayBrowser/#/R-GGA-9617370 α1-antagonists bind ADRA1A,B,D IEA Gallus gallus A0A1D5PRZ3 R-GGA-9623384 https://reactome.org/PathwayBrowser/#/R-GGA-9623384 α1-agonists bind ADRA1A,B,D IEA Gallus gallus A0A1D5PRZ7 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus A0A1D5PRZ7 R-GGA-5694446 https://reactome.org/PathwayBrowser/#/R-GGA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Gallus gallus A0A1D5PRZ7 R-GGA-6807868 https://reactome.org/PathwayBrowser/#/R-GGA-6807868 GBF1 stimulates ARF nucleotide exchange IEA Gallus gallus A0A1D5PRZ7 R-GGA-6807872 https://reactome.org/PathwayBrowser/#/R-GGA-6807872 Active ARF recruits coatomer IEA Gallus gallus A0A1D5PRZ7 R-GGA-6807877 https://reactome.org/PathwayBrowser/#/R-GGA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Gallus gallus A0A1D5PRZ7 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1D5PRZ7 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5PRZ7 R-GGA-6809011 https://reactome.org/PathwayBrowser/#/R-GGA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Gallus gallus A0A1D5PS01 R-GGA-8856189 https://reactome.org/PathwayBrowser/#/R-GGA-8856189 TNFSF8 binds TNFRSF8 IEA Gallus gallus A0A1D5PS29 R-GGA-156930 https://reactome.org/PathwayBrowser/#/R-GGA-156930 GTP-binding activates eEF2 IEA Gallus gallus A0A1D5PS29 R-GGA-5358475 https://reactome.org/PathwayBrowser/#/R-GGA-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Gallus gallus A0A1D5PS29 R-GGA-5358484 https://reactome.org/PathwayBrowser/#/R-GGA-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 IEA Gallus gallus A0A1D5PS29 R-GGA-5358494 https://reactome.org/PathwayBrowser/#/R-GGA-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Gallus gallus A0A1D5PS29 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PS29 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PS29 R-GGA-8932243 https://reactome.org/PathwayBrowser/#/R-GGA-8932243 EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 IEA Gallus gallus A0A1D5PS30 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus A0A1D5PS30 R-GGA-9013009 https://reactome.org/PathwayBrowser/#/R-GGA-9013009 RHOA binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PS30 R-GGA-9013022 https://reactome.org/PathwayBrowser/#/R-GGA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Gallus gallus A0A1D5PS30 R-GGA-9013024 https://reactome.org/PathwayBrowser/#/R-GGA-9013024 RHOB binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PS30 R-GGA-9013110 https://reactome.org/PathwayBrowser/#/R-GGA-9013110 RHOC binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PS30 R-GGA-9013111 https://reactome.org/PathwayBrowser/#/R-GGA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Gallus gallus A0A1D5PS30 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus A0A1D5PS30 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus A0A1D5PS30 R-GGA-9013437 https://reactome.org/PathwayBrowser/#/R-GGA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Gallus gallus A0A1D5PS30 R-GGA-9014295 https://reactome.org/PathwayBrowser/#/R-GGA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Gallus gallus A0A1D5PS30 R-GGA-9014434 https://reactome.org/PathwayBrowser/#/R-GGA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Gallus gallus A0A1D5PS30 R-GGA-9017488 https://reactome.org/PathwayBrowser/#/R-GGA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Gallus gallus A0A1D5PS30 R-GGA-9018745 https://reactome.org/PathwayBrowser/#/R-GGA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Gallus gallus A0A1D5PS30 R-GGA-9018746 https://reactome.org/PathwayBrowser/#/R-GGA-9018746 RHOQ binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PS30 R-GGA-9018806 https://reactome.org/PathwayBrowser/#/R-GGA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Gallus gallus A0A1D5PS30 R-GGA-9693125 https://reactome.org/PathwayBrowser/#/R-GGA-9693125 RHOF binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PS30 R-GGA-9693198 https://reactome.org/PathwayBrowser/#/R-GGA-9693198 RHOD binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PS30 R-GGA-9693282 https://reactome.org/PathwayBrowser/#/R-GGA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Gallus gallus A0A1D5PS30 R-GGA-9696266 https://reactome.org/PathwayBrowser/#/R-GGA-9696266 RND2 binds effectors IEA Gallus gallus A0A1D5PS35 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus A0A1D5PS35 R-GGA-9679787 https://reactome.org/PathwayBrowser/#/R-GGA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Gallus gallus A0A1D5PS36 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5PS37 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus A0A1D5PS44 R-GGA-1606807 https://reactome.org/PathwayBrowser/#/R-GGA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Gallus gallus A0A1D5PS44 R-GGA-1614362 https://reactome.org/PathwayBrowser/#/R-GGA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Gallus gallus A0A1D5PS44 R-GGA-2248891 https://reactome.org/PathwayBrowser/#/R-GGA-2248891 M6PR transports activated ARSA to the lysosome IEA Gallus gallus A0A1D5PS44 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5PS44 R-GGA-9840949 https://reactome.org/PathwayBrowser/#/R-GGA-9840949 ARSA removes sulfate from SM3 IEA Gallus gallus A0A1D5PS56 R-GGA-381487 https://reactome.org/PathwayBrowser/#/R-GGA-381487 IGFBP1 binds IGF forming IGF:IGFBP1 IEA Gallus gallus A0A1D5PS56 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5PS57 R-GGA-2730959 https://reactome.org/PathwayBrowser/#/R-GGA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Gallus gallus A0A1D5PS70 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PS75 R-GGA-3321883 https://reactome.org/PathwayBrowser/#/R-GGA-3321883 MSL acetylates histone H4 IEA Gallus gallus A0A1D5PS87 R-GGA-873918 https://reactome.org/PathwayBrowser/#/R-GGA-873918 Transphosphorylation of JAK1 IEA Gallus gallus A0A1D5PS87 R-GGA-873919 https://reactome.org/PathwayBrowser/#/R-GGA-873919 Phosphorylation of JAK2 IEA Gallus gallus A0A1D5PS87 R-GGA-873921 https://reactome.org/PathwayBrowser/#/R-GGA-873921 Binding of STAT1 to p-IFNGR1 IEA Gallus gallus A0A1D5PS87 R-GGA-873922 https://reactome.org/PathwayBrowser/#/R-GGA-873922 Phosphorylation of STAT1 by JAK kinases IEA Gallus gallus A0A1D5PS87 R-GGA-873924 https://reactome.org/PathwayBrowser/#/R-GGA-873924 Phosphorylation of IFNGR1 by JAK kinases IEA Gallus gallus A0A1D5PS87 R-GGA-873926 https://reactome.org/PathwayBrowser/#/R-GGA-873926 IFNG dimer binds IFNGR IEA Gallus gallus A0A1D5PS87 R-GGA-873927 https://reactome.org/PathwayBrowser/#/R-GGA-873927 Release of STAT1 dimer from active receptor unit IEA Gallus gallus A0A1D5PS87 R-GGA-877269 https://reactome.org/PathwayBrowser/#/R-GGA-877269 SOCS-1 and SOCS-3 binds to p-JAK2 IEA Gallus gallus A0A1D5PS87 R-GGA-909552 https://reactome.org/PathwayBrowser/#/R-GGA-909552 Phosphorylation of STAT1 at Ser727 IEA Gallus gallus A0A1D5PS87 R-GGA-9678561 https://reactome.org/PathwayBrowser/#/R-GGA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Gallus gallus A0A1D5PS87 R-GGA-9732729 https://reactome.org/PathwayBrowser/#/R-GGA-9732729 Activated JAK1 binds RAF1 IEA Gallus gallus A0A1D5PS87 R-GGA-9732738 https://reactome.org/PathwayBrowser/#/R-GGA-9732738 JAK1-mediated phosphorylation of RAF1 IEA Gallus gallus A0A1D5PS87 R-GGA-9732753 https://reactome.org/PathwayBrowser/#/R-GGA-9732753 JAK1-activated RAF1 phosphorylates MAPKs IEA Gallus gallus A0A1D5PS87 R-GGA-9734547 https://reactome.org/PathwayBrowser/#/R-GGA-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Gallus gallus A0A1D5PSB7 R-GGA-449829 https://reactome.org/PathwayBrowser/#/R-GGA-449829 IL11 binds IL11RA IEA Gallus gallus A0A1D5PSB7 R-GGA-449976 https://reactome.org/PathwayBrowser/#/R-GGA-449976 IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) IEA Gallus gallus A0A1D5PSB8 R-GGA-2995389 https://reactome.org/PathwayBrowser/#/R-GGA-2995389 ANKLE2 binds VRK1,(VRK2) IEA Gallus gallus A0A1D5PSC0 R-GGA-428052 https://reactome.org/PathwayBrowser/#/R-GGA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Gallus gallus A0A1D5PSE5 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5PSE5 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PSE5 R-GGA-75848 https://reactome.org/PathwayBrowser/#/R-GGA-75848 ACLY tetramer transforms CIT to Ac-CoA IEA Gallus gallus A0A1D5PSE5 R-GGA-9734540 https://reactome.org/PathwayBrowser/#/R-GGA-9734540 ACLY tetramer binds ETC-1002-CoA IEA Gallus gallus A0A1D5PSF1 R-GGA-8952044 https://reactome.org/PathwayBrowser/#/R-GGA-8952044 AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PSF1 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5PSF1 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5PSH3 R-GGA-8938217 https://reactome.org/PathwayBrowser/#/R-GGA-8938217 RUNX1 binds the SWI/SNF complex IEA Gallus gallus A0A1D5PSH3 R-GGA-9932437 https://reactome.org/PathwayBrowser/#/R-GGA-9932437 ARID1 binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1 IEA Gallus gallus A0A1D5PSH3 R-GGA-9932447 https://reactome.org/PathwayBrowser/#/R-GGA-9932447 SMARCE1 and SMARCB1 bind SMARCC1 dimer:SMARCD1 IEA Gallus gallus A0A1D5PSH3 R-GGA-9932448 https://reactome.org/PathwayBrowser/#/R-GGA-9932448 SMARCC binds SMARCD IEA Gallus gallus A0A1D5PSH3 R-GGA-9932449 https://reactome.org/PathwayBrowser/#/R-GGA-9932449 SMARCE1 and SMARCB1 bind SMARCC dimer:SMARCDs IEA Gallus gallus A0A1D5PSH3 R-GGA-9932450 https://reactome.org/PathwayBrowser/#/R-GGA-9932450 SMARCD1 binds SMARCC1 homodimer IEA Gallus gallus A0A1D5PSH3 R-GGA-9932832 https://reactome.org/PathwayBrowser/#/R-GGA-9932832 BRD7 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2 IEA Gallus gallus A0A1D5PSH3 R-GGA-9932843 https://reactome.org/PathwayBrowser/#/R-GGA-9932843 PHF10 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD7 IEA Gallus gallus A0A1D5PSH3 R-GGA-9933236 https://reactome.org/PathwayBrowser/#/R-GGA-9933236 SS18-containing ATPase complex binds SMARCC dimer:SMARCDs:BICRAs:BRD9 IEA Gallus gallus A0A1D5PSH3 R-GGA-9933237 https://reactome.org/PathwayBrowser/#/R-GGA-9933237 PBRM1-containing ATPase complex binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD&:PHF10 IEA Gallus gallus A0A1D5PSH3 R-GGA-9933238 https://reactome.org/PathwayBrowser/#/R-GGA-9933238 SS18-containing ATPase complex binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1:DPF1,2,3 IEA Gallus gallus A0A1D5PSH3 R-GGA-9934021 https://reactome.org/PathwayBrowser/#/R-GGA-9934021 Formation of neuronal progenitor BAF (npBAF) IEA Gallus gallus A0A1D5PSH3 R-GGA-9934022 https://reactome.org/PathwayBrowser/#/R-GGA-9934022 DPF2, PHF10 bind SMARCC1:SMARCC2 dimer:SMARD1:ARID1A IEA Gallus gallus A0A1D5PSH3 R-GGA-9934024 https://reactome.org/PathwayBrowser/#/R-GGA-9934024 SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10 IEA Gallus gallus A0A1D5PSH3 R-GGA-9934026 https://reactome.org/PathwayBrowser/#/R-GGA-9934026 SMARCE1 and SMARCB1 bind SMARCC1:SMARCC2 dimer:SMARCD1 IEA Gallus gallus A0A1D5PSH3 R-GGA-9934027 https://reactome.org/PathwayBrowser/#/R-GGA-9934027 SMARCC1 and SMARCC2 bind SMARCD1 IEA Gallus gallus A0A1D5PSH8 R-GGA-2025723 https://reactome.org/PathwayBrowser/#/R-GGA-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Gallus gallus A0A1D5PSH8 R-GGA-2046265 https://reactome.org/PathwayBrowser/#/R-GGA-2046265 B4GALTs transfer Gal to the keratan chain IEA Gallus gallus A0A1D5PSH8 R-GGA-2046298 https://reactome.org/PathwayBrowser/#/R-GGA-2046298 B4GALTs transfer Gal to a branch of keratan IEA Gallus gallus A0A1D5PSH8 R-GGA-975919 https://reactome.org/PathwayBrowser/#/R-GGA-975919 Addition of galactose by beta 4-galactosyltransferases IEA Gallus gallus A0A1D5PSI2 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PSI2 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PSI2 R-GGA-73794 https://reactome.org/PathwayBrowser/#/R-GGA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Gallus gallus A0A1D5PSI2 R-GGA-9678749 https://reactome.org/PathwayBrowser/#/R-GGA-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Gallus gallus A0A1D5PSI2 R-GGA-9748945 https://reactome.org/PathwayBrowser/#/R-GGA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Gallus gallus A0A1D5PSI9 R-GGA-1614336 https://reactome.org/PathwayBrowser/#/R-GGA-1614336 SUMF2 binds SUMF1, inhibiting SUMF1-mediated activation of arylsulfatases IEA Gallus gallus A0A1D5PSI9 R-GGA-1614362 https://reactome.org/PathwayBrowser/#/R-GGA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Gallus gallus A0A1D5PSK2 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus A0A1D5PSK2 R-GGA-9013111 https://reactome.org/PathwayBrowser/#/R-GGA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Gallus gallus A0A1D5PSK5 R-GGA-176264 https://reactome.org/PathwayBrowser/#/R-GGA-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Gallus gallus A0A1D5PSK5 R-GGA-5685011 https://reactome.org/PathwayBrowser/#/R-GGA-5685011 ATR activation at DNA DSBs IEA Gallus gallus A0A1D5PSK5 R-GGA-5685156 https://reactome.org/PathwayBrowser/#/R-GGA-5685156 ATR phosphorylates RPA2 IEA Gallus gallus A0A1D5PSK5 R-GGA-5686642 https://reactome.org/PathwayBrowser/#/R-GGA-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Gallus gallus A0A1D5PSK5 R-GGA-5693564 https://reactome.org/PathwayBrowser/#/R-GGA-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Gallus gallus A0A1D5PSK5 R-GGA-5693580 https://reactome.org/PathwayBrowser/#/R-GGA-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Gallus gallus A0A1D5PSK6 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5PSM6 R-GGA-109699 https://reactome.org/PathwayBrowser/#/R-GGA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Gallus gallus A0A1D5PSM6 R-GGA-1307955 https://reactome.org/PathwayBrowser/#/R-GGA-1307955 FGFR4 binds HS:KLB:FGF19 IEA Gallus gallus A0A1D5PSM6 R-GGA-1307963 https://reactome.org/PathwayBrowser/#/R-GGA-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Gallus gallus A0A1D5PSM6 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654151 https://reactome.org/PathwayBrowser/#/R-GGA-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654163 https://reactome.org/PathwayBrowser/#/R-GGA-5654163 Activated FGFR4 binds PLCG1 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654169 https://reactome.org/PathwayBrowser/#/R-GGA-5654169 p-4Y-PLCG1 dissociates from activated FGFR4 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654418 https://reactome.org/PathwayBrowser/#/R-GGA-5654418 Activated FGFR4 phosphorylates FRS2 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654422 https://reactome.org/PathwayBrowser/#/R-GGA-5654422 Activated FGFR4 binds FRS2 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654423 https://reactome.org/PathwayBrowser/#/R-GGA-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654425 https://reactome.org/PathwayBrowser/#/R-GGA-5654425 Activated FGFR4 binds SHC1 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654426 https://reactome.org/PathwayBrowser/#/R-GGA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PSM6 R-GGA-5654428 https://reactome.org/PathwayBrowser/#/R-GGA-5654428 Activated FGFR4 phosphorylates SHC1 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654566 https://reactome.org/PathwayBrowser/#/R-GGA-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654651 https://reactome.org/PathwayBrowser/#/R-GGA-5654651 Activated FGFR4 binds FRS3 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654653 https://reactome.org/PathwayBrowser/#/R-GGA-5654653 Activated FGFR4 phosphorylates FRS3 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654655 https://reactome.org/PathwayBrowser/#/R-GGA-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654658 https://reactome.org/PathwayBrowser/#/R-GGA-5654658 Activated FGFR4:p-FRS bind to PPTN11 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654659 https://reactome.org/PathwayBrowser/#/R-GGA-5654659 Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654662 https://reactome.org/PathwayBrowser/#/R-GGA-5654662 Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Gallus gallus A0A1D5PSM6 R-GGA-5654663 https://reactome.org/PathwayBrowser/#/R-GGA-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PSM6 R-GGA-5654664 https://reactome.org/PathwayBrowser/#/R-GGA-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654667 https://reactome.org/PathwayBrowser/#/R-GGA-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654669 https://reactome.org/PathwayBrowser/#/R-GGA-5654669 Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA IEA Gallus gallus A0A1D5PSM6 R-GGA-5654684 https://reactome.org/PathwayBrowser/#/R-GGA-5654684 CBL ubiquitinates FRS2 and FGFR4 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654714 https://reactome.org/PathwayBrowser/#/R-GGA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654717 https://reactome.org/PathwayBrowser/#/R-GGA-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PSM6 R-GGA-5654734 https://reactome.org/PathwayBrowser/#/R-GGA-5654734 p-CBL:GRB2 binds p-FRS2:activated FGFR4 IEA Gallus gallus A0A1D5PSM6 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5PSM6 R-GGA-8941613 https://reactome.org/PathwayBrowser/#/R-GGA-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PSM9 R-GGA-5340320 https://reactome.org/PathwayBrowser/#/R-GGA-5340320 GLTP transports GSL from plasma membrane to ER membrane IEA Gallus gallus A0A1D5PSP0 R-GGA-8875623 https://reactome.org/PathwayBrowser/#/R-GGA-8875623 SLC25A18,22 import L-Glu, H+ IEA Gallus gallus A0A1D5PSP1 R-GGA-2574840 https://reactome.org/PathwayBrowser/#/R-GGA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Gallus gallus A0A1D5PSP1 R-GGA-2574845 https://reactome.org/PathwayBrowser/#/R-GGA-2574845 AJUBA binds centrosome-associated AURKA IEA Gallus gallus A0A1D5PSP1 R-GGA-3000310 https://reactome.org/PathwayBrowser/#/R-GGA-3000310 AURKA phosphorylates PLK1 IEA Gallus gallus A0A1D5PSP1 R-GGA-3000319 https://reactome.org/PathwayBrowser/#/R-GGA-3000319 BORA binds PLK1 and AURKA IEA Gallus gallus A0A1D5PSP1 R-GGA-380272 https://reactome.org/PathwayBrowser/#/R-GGA-380272 Plk1-mediated phosphorylation of Nlp IEA Gallus gallus A0A1D5PSP1 R-GGA-380283 https://reactome.org/PathwayBrowser/#/R-GGA-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Gallus gallus A0A1D5PSP1 R-GGA-380294 https://reactome.org/PathwayBrowser/#/R-GGA-380294 Loss of C-Nap-1 from centrosomes IEA Gallus gallus A0A1D5PSP1 R-GGA-380311 https://reactome.org/PathwayBrowser/#/R-GGA-380311 Recruitment of Plk1 to centrosomes IEA Gallus gallus A0A1D5PSP1 R-GGA-380455 https://reactome.org/PathwayBrowser/#/R-GGA-380455 Recruitment of CDK11p58 to the centrosomes IEA Gallus gallus A0A1D5PSP1 R-GGA-380508 https://reactome.org/PathwayBrowser/#/R-GGA-380508 Translocation of NuMA to the centrosomes IEA Gallus gallus A0A1D5PSP1 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5PSP1 R-GGA-5626228 https://reactome.org/PathwayBrowser/#/R-GGA-5626228 The distal appendage proteins recruit TTBK2 IEA Gallus gallus A0A1D5PSP1 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1D5PSP1 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1D5PSP1 R-GGA-8853405 https://reactome.org/PathwayBrowser/#/R-GGA-8853405 TPX2 binds AURKA at centrosomes IEA Gallus gallus A0A1D5PSP1 R-GGA-8853419 https://reactome.org/PathwayBrowser/#/R-GGA-8853419 TPX2 promotes AURKA autophosphorylation IEA Gallus gallus A0A1D5PSP4 R-GGA-197186 https://reactome.org/PathwayBrowser/#/R-GGA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Gallus gallus A0A1D5PSP4 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5PSP9 R-GGA-8867667 https://reactome.org/PathwayBrowser/#/R-GGA-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Gallus gallus A0A1D5PSQ6 R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus A0A1D5PSQ6 R-GGA-211910 https://reactome.org/PathwayBrowser/#/R-GGA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Gallus gallus A0A1D5PSQ6 R-GGA-211929 https://reactome.org/PathwayBrowser/#/R-GGA-211929 CYP2C19 5-hydroxylates omeprazole IEA Gallus gallus A0A1D5PSQ6 R-GGA-211966 https://reactome.org/PathwayBrowser/#/R-GGA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Gallus gallus A0A1D5PSQ6 R-GGA-211988 https://reactome.org/PathwayBrowser/#/R-GGA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Gallus gallus A0A1D5PSQ6 R-GGA-211991 https://reactome.org/PathwayBrowser/#/R-GGA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Gallus gallus A0A1D5PSQ6 R-GGA-212004 https://reactome.org/PathwayBrowser/#/R-GGA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Gallus gallus A0A1D5PSQ6 R-GGA-2161814 https://reactome.org/PathwayBrowser/#/R-GGA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Gallus gallus A0A1D5PSQ6 R-GGA-2161899 https://reactome.org/PathwayBrowser/#/R-GGA-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Gallus gallus A0A1D5PSQ6 R-GGA-76354 https://reactome.org/PathwayBrowser/#/R-GGA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Gallus gallus A0A1D5PSQ6 R-GGA-76397 https://reactome.org/PathwayBrowser/#/R-GGA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Gallus gallus A0A1D5PSQ6 R-GGA-76416 https://reactome.org/PathwayBrowser/#/R-GGA-76416 Benzene is hydroxylated to phenol IEA Gallus gallus A0A1D5PSQ6 R-GGA-76434 https://reactome.org/PathwayBrowser/#/R-GGA-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Gallus gallus A0A1D5PSQ6 R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus A0A1D5PSQ6 R-GGA-76475 https://reactome.org/PathwayBrowser/#/R-GGA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Gallus gallus A0A1D5PSQ6 R-GGA-9027043 https://reactome.org/PathwayBrowser/#/R-GGA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Gallus gallus A0A1D5PSQ6 R-GGA-9749986 https://reactome.org/PathwayBrowser/#/R-GGA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Gallus gallus A0A1D5PSQ6 R-GGA-9750016 https://reactome.org/PathwayBrowser/#/R-GGA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Gallus gallus A0A1D5PSQ6 R-GGA-9915971 https://reactome.org/PathwayBrowser/#/R-GGA-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Gallus gallus A0A1D5PSQ6 R-GGA-9915997 https://reactome.org/PathwayBrowser/#/R-GGA-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Gallus gallus A0A1D5PSR5 R-GGA-8855825 https://reactome.org/PathwayBrowser/#/R-GGA-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) IEA Gallus gallus A0A1D5PSS5 R-GGA-194308 https://reactome.org/PathwayBrowser/#/R-GGA-194308 VEGF-C,D bind to VEGFR3 leading to receptor dimerization IEA Gallus gallus A0A1D5PSS5 R-GGA-194310 https://reactome.org/PathwayBrowser/#/R-GGA-194310 VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization IEA Gallus gallus A0A1D5PSS5 R-GGA-195378 https://reactome.org/PathwayBrowser/#/R-GGA-195378 Homodimerization of VEGF proteins IEA Gallus gallus A0A1D5PSS5 R-GGA-481007 https://reactome.org/PathwayBrowser/#/R-GGA-481007 Exocytosis of platelet alpha granule contents IEA Gallus gallus A0A1D5PSY2 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PSZ7 R-GGA-994148 https://reactome.org/PathwayBrowser/#/R-GGA-994148 LRRC16A binds F-actin capping protein IEA Gallus gallus A0A1D5PT06 R-GGA-199910 https://reactome.org/PathwayBrowser/#/R-GGA-199910 MSK1 activates ATF1 IEA Gallus gallus A0A1D5PT17 R-GGA-2029465 https://reactome.org/PathwayBrowser/#/R-GGA-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Gallus gallus A0A1D5PT17 R-GGA-2029466 https://reactome.org/PathwayBrowser/#/R-GGA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Gallus gallus A0A1D5PT17 R-GGA-2029469 https://reactome.org/PathwayBrowser/#/R-GGA-2029469 p-ERK phosphorylates WAVEs and ABI IEA Gallus gallus A0A1D5PT17 R-GGA-2130194 https://reactome.org/PathwayBrowser/#/R-GGA-2130194 ABL phosphorylates WAVEs IEA Gallus gallus A0A1D5PT17 R-GGA-2197690 https://reactome.org/PathwayBrowser/#/R-GGA-2197690 Detachment of WASP/WAVE IEA Gallus gallus A0A1D5PT17 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PT17 R-GGA-9014294 https://reactome.org/PathwayBrowser/#/R-GGA-9014294 RAC2 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PT17 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PT23 R-GGA-8850529 https://reactome.org/PathwayBrowser/#/R-GGA-8850529 RGS proteins bind GNB5 and CCT/TRiC IEA Gallus gallus A0A1D5PT23 R-GGA-8850539 https://reactome.org/PathwayBrowser/#/R-GGA-8850539 Release of GNB5:RGS dimers from CCT/TRiC IEA Gallus gallus A0A1D5PT23 R-GGA-8982012 https://reactome.org/PathwayBrowser/#/R-GGA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Gallus gallus A0A1D5PT23 R-GGA-8982019 https://reactome.org/PathwayBrowser/#/R-GGA-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Gallus gallus A0A1D5PT23 R-GGA-8982020 https://reactome.org/PathwayBrowser/#/R-GGA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Gallus gallus A0A1D5PT30 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5PT30 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5PT30 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5PT30 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5PT30 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5PT51 R-GGA-388824 https://reactome.org/PathwayBrowser/#/R-GGA-388824 PTPRF, PTPRS, PTPRD bind Liprins IEA Gallus gallus A0A1D5PT51 R-GGA-6798257 https://reactome.org/PathwayBrowser/#/R-GGA-6798257 PTPRS binds NTRK3 IEA Gallus gallus A0A1D5PT58 R-GGA-156808 https://reactome.org/PathwayBrowser/#/R-GGA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Gallus gallus A0A1D5PT58 R-GGA-157849 https://reactome.org/PathwayBrowser/#/R-GGA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Gallus gallus A0A1D5PT58 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1D5PT58 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus A0A1D5PT58 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1D5PT58 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1D5PT58 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1D5PT58 R-GGA-72676 https://reactome.org/PathwayBrowser/#/R-GGA-72676 eIF3 and eIF1A bind to the 40S subunit IEA Gallus gallus A0A1D5PT58 R-GGA-72691 https://reactome.org/PathwayBrowser/#/R-GGA-72691 Formation of the 43S pre-initiation complex IEA Gallus gallus A0A1D5PT58 R-GGA-72697 https://reactome.org/PathwayBrowser/#/R-GGA-72697 Start codon recognition IEA Gallus gallus A0A1D5PT58 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1D5PT58 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5PT58 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5PT62 R-GGA-428052 https://reactome.org/PathwayBrowser/#/R-GGA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Gallus gallus A0A1D5PT69 R-GGA-1236943 https://reactome.org/PathwayBrowser/#/R-GGA-1236943 Loading of antigen peptide onto MHC class I molecule IEA Gallus gallus A0A1D5PT69 R-GGA-1236954 https://reactome.org/PathwayBrowser/#/R-GGA-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Gallus gallus A0A1D5PT69 R-GGA-1236964 https://reactome.org/PathwayBrowser/#/R-GGA-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Gallus gallus A0A1D5PT69 R-GGA-1236965 https://reactome.org/PathwayBrowser/#/R-GGA-1236965 Export of peptide loaded MHC class I complex to PM IEA Gallus gallus A0A1D5PT69 R-GGA-198955 https://reactome.org/PathwayBrowser/#/R-GGA-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Gallus gallus A0A1D5PT69 R-GGA-199062 https://reactome.org/PathwayBrowser/#/R-GGA-199062 KLRC1:KLRD1 heterodimer interacts with HLA-E IEA Gallus gallus A0A1D5PT69 R-GGA-210289 https://reactome.org/PathwayBrowser/#/R-GGA-210289 Recruitment of SYK to p-DAP12 IEA Gallus gallus A0A1D5PT69 R-GGA-2395412 https://reactome.org/PathwayBrowser/#/R-GGA-2395412 Phosphorylation of SYK IEA Gallus gallus A0A1D5PT69 R-GGA-2396594 https://reactome.org/PathwayBrowser/#/R-GGA-2396594 Phosphorylation of SLP-76 by p-SYK IEA Gallus gallus A0A1D5PT69 R-GGA-2424480 https://reactome.org/PathwayBrowser/#/R-GGA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PT69 R-GGA-2424482 https://reactome.org/PathwayBrowser/#/R-GGA-2424482 p85 regulatory unit of PI3K binds p-6Y-SYK IEA Gallus gallus A0A1D5PT69 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus A0A1D5PT69 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus A0A1D5PT69 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus A0A1D5PT69 R-GGA-5691154 https://reactome.org/PathwayBrowser/#/R-GGA-5691154 HFE binds TFRC dimer IEA Gallus gallus A0A1D5PT69 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5PT69 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PT69 R-GGA-8863973 https://reactome.org/PathwayBrowser/#/R-GGA-8863973 Fusion of ERC and phagosome IEA Gallus gallus A0A1D5PT69 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus A0A1D5PT69 R-GGA-8951499 https://reactome.org/PathwayBrowser/#/R-GGA-8951499 Loading of antigenic peptides on to class I MHC IEA Gallus gallus A0A1D5PT69 R-GGA-983138 https://reactome.org/PathwayBrowser/#/R-GGA-983138 Transport of MHC heterotrimer to ER exit site IEA Gallus gallus A0A1D5PT69 R-GGA-983145 https://reactome.org/PathwayBrowser/#/R-GGA-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Gallus gallus A0A1D5PT69 R-GGA-983146 https://reactome.org/PathwayBrowser/#/R-GGA-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Gallus gallus A0A1D5PT69 R-GGA-983421 https://reactome.org/PathwayBrowser/#/R-GGA-983421 Journey of cargo through Golgi complex IEA Gallus gallus A0A1D5PT69 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus A0A1D5PT69 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus A0A1D5PT69 R-GGA-983425 https://reactome.org/PathwayBrowser/#/R-GGA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Gallus gallus A0A1D5PT69 R-GGA-983427 https://reactome.org/PathwayBrowser/#/R-GGA-983427 Expression of peptide bound class I MHC on cell surface IEA Gallus gallus A0A1D5PT78 R-GGA-166015 https://reactome.org/PathwayBrowser/#/R-GGA-166015 Association of LBP with LPS IEA Gallus gallus A0A1D5PT78 R-GGA-166038 https://reactome.org/PathwayBrowser/#/R-GGA-166038 GPI-bound CD14 binds LPS IEA Gallus gallus A0A1D5PT78 R-GGA-169719 https://reactome.org/PathwayBrowser/#/R-GGA-169719 Secreted CD14 binds LPS IEA Gallus gallus A0A1D5PT78 R-GGA-8869683 https://reactome.org/PathwayBrowser/#/R-GGA-8869683 oxPL binds LBP IEA Gallus gallus A0A1D5PT80 R-GGA-6807877 https://reactome.org/PathwayBrowser/#/R-GGA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Gallus gallus A0A1D5PT80 R-GGA-6811417 https://reactome.org/PathwayBrowser/#/R-GGA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Gallus gallus A0A1D5PT80 R-GGA-6811418 https://reactome.org/PathwayBrowser/#/R-GGA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Gallus gallus A0A1D5PT81 R-GGA-372448 https://reactome.org/PathwayBrowser/#/R-GGA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Gallus gallus A0A1D5PT95 R-GGA-1168636 https://reactome.org/PathwayBrowser/#/R-GGA-1168636 p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP IEA Gallus gallus A0A1D5PT95 R-GGA-1250383 https://reactome.org/PathwayBrowser/#/R-GGA-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Gallus gallus A0A1D5PT95 R-GGA-1306972 https://reactome.org/PathwayBrowser/#/R-GGA-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Gallus gallus A0A1D5PT95 R-GGA-1433471 https://reactome.org/PathwayBrowser/#/R-GGA-1433471 Activation of RAS by p-KIT bound SOS1 IEA Gallus gallus A0A1D5PT95 R-GGA-170986 https://reactome.org/PathwayBrowser/#/R-GGA-170986 Ral-GDS binds to Ras-GTP IEA Gallus gallus A0A1D5PT95 R-GGA-177938 https://reactome.org/PathwayBrowser/#/R-GGA-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Gallus gallus A0A1D5PT95 R-GGA-177945 https://reactome.org/PathwayBrowser/#/R-GGA-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Gallus gallus A0A1D5PT95 R-GGA-186834 https://reactome.org/PathwayBrowser/#/R-GGA-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Gallus gallus A0A1D5PT95 R-GGA-210977 https://reactome.org/PathwayBrowser/#/R-GGA-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Gallus gallus A0A1D5PT95 R-GGA-2179407 https://reactome.org/PathwayBrowser/#/R-GGA-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Gallus gallus A0A1D5PT95 R-GGA-2424477 https://reactome.org/PathwayBrowser/#/R-GGA-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Gallus gallus A0A1D5PT95 R-GGA-392054 https://reactome.org/PathwayBrowser/#/R-GGA-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Gallus gallus A0A1D5PT95 R-GGA-4332359 https://reactome.org/PathwayBrowser/#/R-GGA-4332359 Active calmodulin binds CAMK2 IEA Gallus gallus A0A1D5PT95 R-GGA-5218845 https://reactome.org/PathwayBrowser/#/R-GGA-5218845 p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate IEA Gallus gallus A0A1D5PT95 R-GGA-5624486 https://reactome.org/PathwayBrowser/#/R-GGA-5624486 SFKs phosphorylates RAF1 on Y340,Y341 IEA Gallus gallus A0A1D5PT95 R-GGA-5624492 https://reactome.org/PathwayBrowser/#/R-GGA-5624492 PAK phosphorylates p21 RAF1 on S338 IEA Gallus gallus A0A1D5PT95 R-GGA-5624494 https://reactome.org/PathwayBrowser/#/R-GGA-5624494 RAF1 binds p21 RAS:GTP IEA Gallus gallus A0A1D5PT95 R-GGA-5654392 https://reactome.org/PathwayBrowser/#/R-GGA-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PT95 R-GGA-5654402 https://reactome.org/PathwayBrowser/#/R-GGA-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PT95 R-GGA-5654413 https://reactome.org/PathwayBrowser/#/R-GGA-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PT95 R-GGA-5654426 https://reactome.org/PathwayBrowser/#/R-GGA-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PT95 R-GGA-5654600 https://reactome.org/PathwayBrowser/#/R-GGA-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PT95 R-GGA-5654618 https://reactome.org/PathwayBrowser/#/R-GGA-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PT95 R-GGA-5654647 https://reactome.org/PathwayBrowser/#/R-GGA-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PT95 R-GGA-5654663 https://reactome.org/PathwayBrowser/#/R-GGA-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PT95 R-GGA-5658231 https://reactome.org/PathwayBrowser/#/R-GGA-5658231 RAS GAPs stimulate RAS GTPase activity IEA Gallus gallus A0A1D5PT95 R-GGA-5658435 https://reactome.org/PathwayBrowser/#/R-GGA-5658435 RAS GAPs bind RAS:GTP IEA Gallus gallus A0A1D5PT95 R-GGA-5672950 https://reactome.org/PathwayBrowser/#/R-GGA-5672950 "Activator" RAF:YWHAB dimer binds RAS:GTP IEA Gallus gallus A0A1D5PT95 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5PT95 R-GGA-5672966 https://reactome.org/PathwayBrowser/#/R-GGA-5672966 RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers IEA Gallus gallus A0A1D5PT95 R-GGA-5672969 https://reactome.org/PathwayBrowser/#/R-GGA-5672969 Phosphorylation of RAF IEA Gallus gallus A0A1D5PT95 R-GGA-5672972 https://reactome.org/PathwayBrowser/#/R-GGA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Gallus gallus A0A1D5PT95 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus A0A1D5PT95 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus A0A1D5PT95 R-GGA-5672980 https://reactome.org/PathwayBrowser/#/R-GGA-5672980 Dissociation of RAS:RAF complex IEA Gallus gallus A0A1D5PT95 R-GGA-5674018 https://reactome.org/PathwayBrowser/#/R-GGA-5674018 BRAP binds RAS:GTP IEA Gallus gallus A0A1D5PT95 R-GGA-5674022 https://reactome.org/PathwayBrowser/#/R-GGA-5674022 BRAP autoubiquitinates IEA Gallus gallus A0A1D5PT95 R-GGA-5675417 https://reactome.org/PathwayBrowser/#/R-GGA-5675417 PEBP1 binds activated RAF1 IEA Gallus gallus A0A1D5PT95 R-GGA-8851827 https://reactome.org/PathwayBrowser/#/R-GGA-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Gallus gallus A0A1D5PT95 R-GGA-8851877 https://reactome.org/PathwayBrowser/#/R-GGA-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Gallus gallus A0A1D5PT95 R-GGA-8851899 https://reactome.org/PathwayBrowser/#/R-GGA-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Gallus gallus A0A1D5PT95 R-GGA-8941613 https://reactome.org/PathwayBrowser/#/R-GGA-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PT95 R-GGA-8941618 https://reactome.org/PathwayBrowser/#/R-GGA-8941618 Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PT95 R-GGA-8941623 https://reactome.org/PathwayBrowser/#/R-GGA-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PT95 R-GGA-8941628 https://reactome.org/PathwayBrowser/#/R-GGA-8941628 Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Gallus gallus A0A1D5PT95 R-GGA-8981353 https://reactome.org/PathwayBrowser/#/R-GGA-8981353 RASA1 stimulates RAS GTPase activity IEA Gallus gallus A0A1D5PT95 R-GGA-8981355 https://reactome.org/PathwayBrowser/#/R-GGA-8981355 RASA1 binds RAS:GTP IEA Gallus gallus A0A1D5PT95 R-GGA-9607304 https://reactome.org/PathwayBrowser/#/R-GGA-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Gallus gallus A0A1D5PT95 R-GGA-9632906 https://reactome.org/PathwayBrowser/#/R-GGA-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Gallus gallus A0A1D5PT95 R-GGA-9632910 https://reactome.org/PathwayBrowser/#/R-GGA-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Gallus gallus A0A1D5PT95 R-GGA-9632918 https://reactome.org/PathwayBrowser/#/R-GGA-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Gallus gallus A0A1D5PT95 R-GGA-9647977 https://reactome.org/PathwayBrowser/#/R-GGA-9647977 ICMT methylates S-Farn RAS proteins IEA Gallus gallus A0A1D5PT95 R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus A0A1D5PT95 R-GGA-9647980 https://reactome.org/PathwayBrowser/#/R-GGA-9647980 mature RAS proteins translocate to plasma membrane IEA Gallus gallus A0A1D5PT95 R-GGA-9647982 https://reactome.org/PathwayBrowser/#/R-GGA-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated IEA Gallus gallus A0A1D5PT95 R-GGA-9647994 https://reactome.org/PathwayBrowser/#/R-GGA-9647994 RAS proteins are depalmitoylated IEA Gallus gallus A0A1D5PT95 R-GGA-9649732 https://reactome.org/PathwayBrowser/#/R-GGA-9649732 Mature S-Farn-Me KRAS4B translocates to plasma membrane IEA Gallus gallus A0A1D5PT95 R-GGA-9649733 https://reactome.org/PathwayBrowser/#/R-GGA-9649733 mature p21 RAS binds GDP IEA Gallus gallus A0A1D5PT95 R-GGA-9649735 https://reactome.org/PathwayBrowser/#/R-GGA-9649735 Intrinsic nucleotide exchange on RAS IEA Gallus gallus A0A1D5PT95 R-GGA-9649736 https://reactome.org/PathwayBrowser/#/R-GGA-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP IEA Gallus gallus A0A1D5PT95 R-GGA-9653108 https://reactome.org/PathwayBrowser/#/R-GGA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Gallus gallus A0A1D5PT95 R-GGA-9653503 https://reactome.org/PathwayBrowser/#/R-GGA-9653503 KRAS4B is phosphorylated on serine 181 IEA Gallus gallus A0A1D5PT95 R-GGA-9653585 https://reactome.org/PathwayBrowser/#/R-GGA-9653585 S-Farn-Me KRAS4B binds calmodulin IEA Gallus gallus A0A1D5PT95 R-GGA-9653592 https://reactome.org/PathwayBrowser/#/R-GGA-9653592 pS181-S-Farn-Me KRAS4B translocates to the outer mitochondrial membrane IEA Gallus gallus A0A1D5PT95 R-GGA-9653595 https://reactome.org/PathwayBrowser/#/R-GGA-9653595 pS181-S-Farn-Me KRAS4B binds BCL2L1 IEA Gallus gallus A0A1D5PT95 R-GGA-9654521 https://reactome.org/PathwayBrowser/#/R-GGA-9654521 Calmodulin dissociates KRAS4B from the plasma membrane IEA Gallus gallus A0A1D5PT95 R-GGA-9654525 https://reactome.org/PathwayBrowser/#/R-GGA-9654525 PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ IEA Gallus gallus A0A1D5PT95 R-GGA-9657599 https://reactome.org/PathwayBrowser/#/R-GGA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Gallus gallus A0A1D5PT95 R-GGA-9657603 https://reactome.org/PathwayBrowser/#/R-GGA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Gallus gallus A0A1D5PT95 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus A0A1D5PT95 R-GGA-9657608 https://reactome.org/PathwayBrowser/#/R-GGA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Gallus gallus A0A1D5PT95 R-GGA-9658253 https://reactome.org/PathwayBrowser/#/R-GGA-9658253 RAS:GTP binds PI3K IEA Gallus gallus A0A1D5PT95 R-GGA-9674816 https://reactome.org/PathwayBrowser/#/R-GGA-9674816 p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS IEA Gallus gallus A0A1D5PTA6 R-GGA-996755 https://reactome.org/PathwayBrowser/#/R-GGA-996755 ZFPM proteins bind GATA proteins IEA Gallus gallus A0A1D5PTC4 R-GGA-8852013 https://reactome.org/PathwayBrowser/#/R-GGA-8852013 BTNL8 binds resting T cell surface IEA Gallus gallus A0A1D5PTD9 R-GGA-444120 https://reactome.org/PathwayBrowser/#/R-GGA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Gallus gallus A0A1D5PTH5 R-GGA-6810843 https://reactome.org/PathwayBrowser/#/R-GGA-6810843 Envoplakin binds periplakin IEA Gallus gallus A0A1D5PTH5 R-GGA-6814187 https://reactome.org/PathwayBrowser/#/R-GGA-6814187 EVL:PPL heterodimer binds the inner surface of the plasma membrane IEA Gallus gallus A0A1D5PTH5 R-GGA-8938431 https://reactome.org/PathwayBrowser/#/R-GGA-8938431 BTN3A1 and BTN1A1 binds periplakin (PPL) IEA Gallus gallus A0A1D5PTI9 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PTI9 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PTI9 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PTI9 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PTJ5 R-GGA-176264 https://reactome.org/PathwayBrowser/#/R-GGA-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Gallus gallus A0A1D5PTJ5 R-GGA-5685011 https://reactome.org/PathwayBrowser/#/R-GGA-5685011 ATR activation at DNA DSBs IEA Gallus gallus A0A1D5PTJ5 R-GGA-5685156 https://reactome.org/PathwayBrowser/#/R-GGA-5685156 ATR phosphorylates RPA2 IEA Gallus gallus A0A1D5PTJ5 R-GGA-5686642 https://reactome.org/PathwayBrowser/#/R-GGA-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Gallus gallus A0A1D5PTJ5 R-GGA-5693564 https://reactome.org/PathwayBrowser/#/R-GGA-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Gallus gallus A0A1D5PTJ5 R-GGA-5693580 https://reactome.org/PathwayBrowser/#/R-GGA-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Gallus gallus A0A1D5PTJ8 R-GGA-3225851 https://reactome.org/PathwayBrowser/#/R-GGA-3225851 ROS oxidize thioredoxin and activate MAP3K5 IEA Gallus gallus A0A1D5PTJ8 R-GGA-3228469 https://reactome.org/PathwayBrowser/#/R-GGA-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Gallus gallus A0A1D5PTK4 R-GGA-6797100 https://reactome.org/PathwayBrowser/#/R-GGA-6797100 CCNK binds CDK13 IEA Gallus gallus A0A1D5PTK4 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PTL0 R-GGA-2404199 https://reactome.org/PathwayBrowser/#/R-GGA-2404199 IGF1,2:IGF1R autophosphorylates IEA Gallus gallus A0A1D5PTL6 R-GGA-5624949 https://reactome.org/PathwayBrowser/#/R-GGA-5624949 Assembly of the anterograde IFT train IEA Gallus gallus A0A1D5PTL6 R-GGA-5625416 https://reactome.org/PathwayBrowser/#/R-GGA-5625416 Anterograde IFT IEA Gallus gallus A0A1D5PTL6 R-GGA-5625426 https://reactome.org/PathwayBrowser/#/R-GGA-5625426 Retrograde IFT IEA Gallus gallus A0A1D5PTQ5 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1D5PTQ5 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5PTQ5 R-GGA-419389 https://reactome.org/PathwayBrowser/#/R-GGA-419389 LPA-binding receptors bind LPA IEA Gallus gallus A0A1D5PTQ5 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1D5PTQ5 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1D5PTQ5 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5PTQ5 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5PTR5 R-GGA-354066 https://reactome.org/PathwayBrowser/#/R-GGA-354066 Translocation of PTK2 to Focal complexes IEA Gallus gallus A0A1D5PTR5 R-GGA-354073 https://reactome.org/PathwayBrowser/#/R-GGA-354073 Autophosphorylation of PTK2 at Y397 IEA Gallus gallus A0A1D5PTR5 R-GGA-354077 https://reactome.org/PathwayBrowser/#/R-GGA-354077 Integrin alphaIIb beta3 activation IEA Gallus gallus A0A1D5PTR5 R-GGA-354087 https://reactome.org/PathwayBrowser/#/R-GGA-354087 Recruitment of GRB2 to p-PTK2 IEA Gallus gallus A0A1D5PTR5 R-GGA-354097 https://reactome.org/PathwayBrowser/#/R-GGA-354097 Activation of Talin IEA Gallus gallus A0A1D5PTR5 R-GGA-354124 https://reactome.org/PathwayBrowser/#/R-GGA-354124 Phosphorylation of pPTK2 by SRC IEA Gallus gallus A0A1D5PTR5 R-GGA-354149 https://reactome.org/PathwayBrowser/#/R-GGA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Gallus gallus A0A1D5PTR5 R-GGA-354165 https://reactome.org/PathwayBrowser/#/R-GGA-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Gallus gallus A0A1D5PTR5 R-GGA-372693 https://reactome.org/PathwayBrowser/#/R-GGA-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Gallus gallus A0A1D5PTR5 R-GGA-372697 https://reactome.org/PathwayBrowser/#/R-GGA-372697 Crk binding to p130cas IEA Gallus gallus A0A1D5PTR5 R-GGA-372705 https://reactome.org/PathwayBrowser/#/R-GGA-372705 Recruitment of BCAR1 to PTK2 complex IEA Gallus gallus A0A1D5PTR5 R-GGA-377640 https://reactome.org/PathwayBrowser/#/R-GGA-377640 Autophosphorylation of SRC IEA Gallus gallus A0A1D5PTR5 R-GGA-377641 https://reactome.org/PathwayBrowser/#/R-GGA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Gallus gallus A0A1D5PTR5 R-GGA-377643 https://reactome.org/PathwayBrowser/#/R-GGA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Gallus gallus A0A1D5PTR5 R-GGA-377644 https://reactome.org/PathwayBrowser/#/R-GGA-377644 Release of CSK from SRC IEA Gallus gallus A0A1D5PTR5 R-GGA-399936 https://reactome.org/PathwayBrowser/#/R-GGA-399936 Inhibition of integrin activation by sequestering PIP5KIgamma IEA Gallus gallus A0A1D5PTR5 R-GGA-429415 https://reactome.org/PathwayBrowser/#/R-GGA-429415 SYK binds to integrin alphaIIb beta3 IEA Gallus gallus A0A1D5PTR5 R-GGA-429441 https://reactome.org/PathwayBrowser/#/R-GGA-429441 SYK activation by SRC IEA Gallus gallus A0A1D5PTR5 R-GGA-432096 https://reactome.org/PathwayBrowser/#/R-GGA-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Gallus gallus A0A1D5PTR5 R-GGA-443905 https://reactome.org/PathwayBrowser/#/R-GGA-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Gallus gallus A0A1D5PTR5 R-GGA-443910 https://reactome.org/PathwayBrowser/#/R-GGA-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Gallus gallus A0A1D5PTR5 R-GGA-445699 https://reactome.org/PathwayBrowser/#/R-GGA-445699 ATP Hydrolysis By Myosin IEA Gallus gallus A0A1D5PTR5 R-GGA-445700 https://reactome.org/PathwayBrowser/#/R-GGA-445700 Myosin Binds ATP IEA Gallus gallus A0A1D5PTR5 R-GGA-445704 https://reactome.org/PathwayBrowser/#/R-GGA-445704 Calcium Binds Caldesmon IEA Gallus gallus A0A1D5PTR5 R-GGA-445705 https://reactome.org/PathwayBrowser/#/R-GGA-445705 Release Of ADP From Myosin IEA Gallus gallus A0A1D5PTR5 R-GGA-482772 https://reactome.org/PathwayBrowser/#/R-GGA-482772 Release of platelet cytosolic components IEA Gallus gallus A0A1D5PTR5 R-GGA-5672972 https://reactome.org/PathwayBrowser/#/R-GGA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Gallus gallus A0A1D5PTR5 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus A0A1D5PTR5 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus A0A1D5PTR5 R-GGA-5672980 https://reactome.org/PathwayBrowser/#/R-GGA-5672980 Dissociation of RAS:RAF complex IEA Gallus gallus A0A1D5PTR5 R-GGA-9657599 https://reactome.org/PathwayBrowser/#/R-GGA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Gallus gallus A0A1D5PTR5 R-GGA-9657603 https://reactome.org/PathwayBrowser/#/R-GGA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Gallus gallus A0A1D5PTR5 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus A0A1D5PTR5 R-GGA-9657608 https://reactome.org/PathwayBrowser/#/R-GGA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Gallus gallus A0A1D5PTT4 R-GGA-1971483 https://reactome.org/PathwayBrowser/#/R-GGA-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Gallus gallus A0A1D5PTU3 R-GGA-5668414 https://reactome.org/PathwayBrowser/#/R-GGA-5668414 TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK IEA Gallus gallus A0A1D5PTU3 R-GGA-6799350 https://reactome.org/PathwayBrowser/#/R-GGA-6799350 Exocytosis of specific granule membrane proteins IEA Gallus gallus A0A1D5PTU5 R-GGA-5691512 https://reactome.org/PathwayBrowser/#/R-GGA-5691512 APEH hydrolyses NAc-Ser-protein IEA Gallus gallus A0A1D5PTU5 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PTV1 R-GGA-5696183 https://reactome.org/PathwayBrowser/#/R-GGA-5696183 AOC3 deaminates BZAM IEA Gallus gallus A0A1D5PU00 R-GGA-2168881 https://reactome.org/PathwayBrowser/#/R-GGA-2168881 Truncated Alpha-1-Microglobulin binds heme IEA Gallus gallus A0A1D5PU00 R-GGA-2168888 https://reactome.org/PathwayBrowser/#/R-GGA-2168888 Alpha1-Microglobulin binds heme IEA Gallus gallus A0A1D5PU00 R-GGA-2203516 https://reactome.org/PathwayBrowser/#/R-GGA-2203516 Alpha-1-Microglobulin is cleaved IEA Gallus gallus A0A1D5PU01 R-GGA-212222 https://reactome.org/PathwayBrowser/#/R-GGA-212222 PRC2 recruits DNA methyltransferases IEA Gallus gallus A0A1D5PU01 R-GGA-212269 https://reactome.org/PathwayBrowser/#/R-GGA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Gallus gallus A0A1D5PU01 R-GGA-4655431 https://reactome.org/PathwayBrowser/#/R-GGA-4655431 SUMOyation of DNMT1 with SUMO1 IEA Gallus gallus A0A1D5PU09 R-GGA-430341 https://reactome.org/PathwayBrowser/#/R-GGA-430341 Mig-2 recruits Migfilin to the cell-ECM adhesions IEA Gallus gallus A0A1D5PU09 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PU09 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PU23 R-GGA-3785768 https://reactome.org/PathwayBrowser/#/R-GGA-3785768 MRN complex binds DNA double strand breaks IEA Gallus gallus A0A1D5PU23 R-GGA-5682018 https://reactome.org/PathwayBrowser/#/R-GGA-5682018 MRN complex bound to shortened telomeres recruits ATM IEA Gallus gallus A0A1D5PU23 R-GGA-5682020 https://reactome.org/PathwayBrowser/#/R-GGA-5682020 MRN complex binds shortened telomeres IEA Gallus gallus A0A1D5PU23 R-GGA-5682026 https://reactome.org/PathwayBrowser/#/R-GGA-5682026 MRN bound to shortened telomeres activates ATM IEA Gallus gallus A0A1D5PU23 R-GGA-5682044 https://reactome.org/PathwayBrowser/#/R-GGA-5682044 KAT5 acetylates ATM at DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5682586 https://reactome.org/PathwayBrowser/#/R-GGA-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5682588 https://reactome.org/PathwayBrowser/#/R-GGA-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5682598 https://reactome.org/PathwayBrowser/#/R-GGA-5682598 ATM phosphorylates HERC2 IEA Gallus gallus A0A1D5PU23 R-GGA-5682607 https://reactome.org/PathwayBrowser/#/R-GGA-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5682629 https://reactome.org/PathwayBrowser/#/R-GGA-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Gallus gallus A0A1D5PU23 R-GGA-5682858 https://reactome.org/PathwayBrowser/#/R-GGA-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Gallus gallus A0A1D5PU23 R-GGA-5682863 https://reactome.org/PathwayBrowser/#/R-GGA-5682863 RNF168 binds DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5682965 https://reactome.org/PathwayBrowser/#/R-GGA-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5682967 https://reactome.org/PathwayBrowser/#/R-GGA-5682967 WHSC1 binds DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5682983 https://reactome.org/PathwayBrowser/#/R-GGA-5682983 ATM phosphorylates WHSC1 IEA Gallus gallus A0A1D5PU23 R-GGA-5682992 https://reactome.org/PathwayBrowser/#/R-GGA-5682992 KDM4A,B bind H4K20Me2 IEA Gallus gallus A0A1D5PU23 R-GGA-5683077 https://reactome.org/PathwayBrowser/#/R-GGA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Gallus gallus A0A1D5PU23 R-GGA-5683384 https://reactome.org/PathwayBrowser/#/R-GGA-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5683385 https://reactome.org/PathwayBrowser/#/R-GGA-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5683425 https://reactome.org/PathwayBrowser/#/R-GGA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5683735 https://reactome.org/PathwayBrowser/#/R-GGA-5683735 CHEK2 is recruited to DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5683801 https://reactome.org/PathwayBrowser/#/R-GGA-5683801 CHEK2 phosphorylates BRCA1 IEA Gallus gallus A0A1D5PU23 R-GGA-5683964 https://reactome.org/PathwayBrowser/#/R-GGA-5683964 ATM phosphorylates EYA1-4 IEA Gallus gallus A0A1D5PU23 R-GGA-5683967 https://reactome.org/PathwayBrowser/#/R-GGA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Gallus gallus A0A1D5PU23 R-GGA-5683986 https://reactome.org/PathwayBrowser/#/R-GGA-5683986 APBB1 and MAPK8 bind diphosphorylated H2AFX IEA Gallus gallus A0A1D5PU23 R-GGA-5684006 https://reactome.org/PathwayBrowser/#/R-GGA-5684006 KPNA2 translocates NBN to the nucleus IEA Gallus gallus A0A1D5PU23 R-GGA-5684008 https://reactome.org/PathwayBrowser/#/R-GGA-5684008 NBN binds KPNA2 IEA Gallus gallus A0A1D5PU23 R-GGA-5684052 https://reactome.org/PathwayBrowser/#/R-GGA-5684052 PIAS4 SUMOylates MDC1 IEA Gallus gallus A0A1D5PU23 R-GGA-5684081 https://reactome.org/PathwayBrowser/#/R-GGA-5684081 MRN complex binds CDK2 and RBBP8 IEA Gallus gallus A0A1D5PU23 R-GGA-5684096 https://reactome.org/PathwayBrowser/#/R-GGA-5684096 CDK2 phosphorylates RBBP8 IEA Gallus gallus A0A1D5PU23 R-GGA-5684108 https://reactome.org/PathwayBrowser/#/R-GGA-5684108 BRCA1 binds phosphorylated RBBP8 IEA Gallus gallus A0A1D5PU23 R-GGA-5684140 https://reactome.org/PathwayBrowser/#/R-GGA-5684140 ATM phosphorylates RBBP8 IEA Gallus gallus A0A1D5PU23 R-GGA-5684875 https://reactome.org/PathwayBrowser/#/R-GGA-5684875 Binding of ATR:ATRIP to RPA at resected DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5685011 https://reactome.org/PathwayBrowser/#/R-GGA-5685011 ATR activation at DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5685156 https://reactome.org/PathwayBrowser/#/R-GGA-5685156 ATR phosphorylates RPA2 IEA Gallus gallus A0A1D5PU23 R-GGA-5685341 https://reactome.org/PathwayBrowser/#/R-GGA-5685341 BCDX2 complex stabilizes RAD51 filament IEA Gallus gallus A0A1D5PU23 R-GGA-5685838 https://reactome.org/PathwayBrowser/#/R-GGA-5685838 CX3 complex binds D-loop structures IEA Gallus gallus A0A1D5PU23 R-GGA-5685985 https://reactome.org/PathwayBrowser/#/R-GGA-5685985 EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment IEA Gallus gallus A0A1D5PU23 R-GGA-5685994 https://reactome.org/PathwayBrowser/#/R-GGA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Gallus gallus A0A1D5PU23 R-GGA-5686642 https://reactome.org/PathwayBrowser/#/R-GGA-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5686685 https://reactome.org/PathwayBrowser/#/R-GGA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5686704 https://reactome.org/PathwayBrowser/#/R-GGA-5686704 Activated ATM phosphorylates DCLRE1C IEA Gallus gallus A0A1D5PU23 R-GGA-5686900 https://reactome.org/PathwayBrowser/#/R-GGA-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Gallus gallus A0A1D5PU23 R-GGA-5687464 https://reactome.org/PathwayBrowser/#/R-GGA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Gallus gallus A0A1D5PU23 R-GGA-5687465 https://reactome.org/PathwayBrowser/#/R-GGA-5687465 MRN complex binds RBBP8 IEA Gallus gallus A0A1D5PU23 R-GGA-5687484 https://reactome.org/PathwayBrowser/#/R-GGA-5687484 PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site IEA Gallus gallus A0A1D5PU23 R-GGA-5687640 https://reactome.org/PathwayBrowser/#/R-GGA-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Gallus gallus A0A1D5PU23 R-GGA-5687653 https://reactome.org/PathwayBrowser/#/R-GGA-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Gallus gallus A0A1D5PU23 R-GGA-5687664 https://reactome.org/PathwayBrowser/#/R-GGA-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Gallus gallus A0A1D5PU23 R-GGA-5687673 https://reactome.org/PathwayBrowser/#/R-GGA-5687673 MRN recruits LIG3:XRCC1 to MMEJ sites IEA Gallus gallus A0A1D5PU23 R-GGA-5687675 https://reactome.org/PathwayBrowser/#/R-GGA-5687675 LIG3 ligates remaining SSBs in MMEJ IEA Gallus gallus A0A1D5PU23 R-GGA-5693536 https://reactome.org/PathwayBrowser/#/R-GGA-5693536 ATM phosphorylates MDC1 IEA Gallus gallus A0A1D5PU23 R-GGA-5693539 https://reactome.org/PathwayBrowser/#/R-GGA-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Gallus gallus A0A1D5PU23 R-GGA-5693540 https://reactome.org/PathwayBrowser/#/R-GGA-5693540 MRN activates ATM IEA Gallus gallus A0A1D5PU23 R-GGA-5693542 https://reactome.org/PathwayBrowser/#/R-GGA-5693542 Association of RPA complexes with ssDNA at resected DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5693549 https://reactome.org/PathwayBrowser/#/R-GGA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5693551 https://reactome.org/PathwayBrowser/#/R-GGA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Gallus gallus A0A1D5PU23 R-GGA-5693564 https://reactome.org/PathwayBrowser/#/R-GGA-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Gallus gallus A0A1D5PU23 R-GGA-5693566 https://reactome.org/PathwayBrowser/#/R-GGA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5693580 https://reactome.org/PathwayBrowser/#/R-GGA-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Gallus gallus A0A1D5PU23 R-GGA-5693584 https://reactome.org/PathwayBrowser/#/R-GGA-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Gallus gallus A0A1D5PU23 R-GGA-5693593 https://reactome.org/PathwayBrowser/#/R-GGA-5693593 D-loop extension by DNA polymerases IEA Gallus gallus A0A1D5PU23 R-GGA-5693598 https://reactome.org/PathwayBrowser/#/R-GGA-5693598 ATM phosphorylates NBN IEA Gallus gallus A0A1D5PU23 R-GGA-5693602 https://reactome.org/PathwayBrowser/#/R-GGA-5693602 ATM recognizes H2AFX-Nucleosomes IEA Gallus gallus A0A1D5PU23 R-GGA-5693608 https://reactome.org/PathwayBrowser/#/R-GGA-5693608 Initial resection of double-strand break ends IEA Gallus gallus A0A1D5PU23 R-GGA-5693612 https://reactome.org/PathwayBrowser/#/R-GGA-5693612 MRN complex bound to DNA ends recruits ATM IEA Gallus gallus A0A1D5PU23 R-GGA-5693620 https://reactome.org/PathwayBrowser/#/R-GGA-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Gallus gallus A0A1D5PU23 R-GGA-6792712 https://reactome.org/PathwayBrowser/#/R-GGA-6792712 KAT5 acetylates ATM at shortened telomeres IEA Gallus gallus A0A1D5PU23 R-GGA-69891 https://reactome.org/PathwayBrowser/#/R-GGA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Gallus gallus A0A1D5PU23 R-GGA-75174 https://reactome.org/PathwayBrowser/#/R-GGA-75174 Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction IEA Gallus gallus A0A1D5PU23 R-GGA-9853389 https://reactome.org/PathwayBrowser/#/R-GGA-9853389 FIGNL1 binds RAD51 IEA Gallus gallus A0A1D5PU31 R-GGA-8952251 https://reactome.org/PathwayBrowser/#/R-GGA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Gallus gallus A0A1D5PU34 R-GGA-6794347 https://reactome.org/PathwayBrowser/#/R-GGA-6794347 Homer1,2,3 dimerizes IEA Gallus gallus A0A1D5PU34 R-GGA-6794355 https://reactome.org/PathwayBrowser/#/R-GGA-6794355 Homer1,2,3 binds mGluR1a,5 IEA Gallus gallus A0A1D5PU41 R-GGA-140736 https://reactome.org/PathwayBrowser/#/R-GGA-140736 factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) IEA Gallus gallus A0A1D5PU41 R-GGA-140748 https://reactome.org/PathwayBrowser/#/R-GGA-140748 tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex IEA Gallus gallus A0A1D5PU41 R-GGA-140769 https://reactome.org/PathwayBrowser/#/R-GGA-140769 factor VII -> factor VIIa IEA Gallus gallus A0A1D5PU41 R-GGA-140777 https://reactome.org/PathwayBrowser/#/R-GGA-140777 factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) IEA Gallus gallus A0A1D5PU41 R-GGA-140783 https://reactome.org/PathwayBrowser/#/R-GGA-140783 tissue factor (TF) + factor VII (F7) -> TF:F7 complex IEA Gallus gallus A0A1D5PU41 R-GGA-140823 https://reactome.org/PathwayBrowser/#/R-GGA-140823 factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) IEA Gallus gallus A0A1D5PU41 R-GGA-140825 https://reactome.org/PathwayBrowser/#/R-GGA-140825 TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa IEA Gallus gallus A0A1D5PU41 R-GGA-159783 https://reactome.org/PathwayBrowser/#/R-GGA-159783 Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus IEA Gallus gallus A0A1D5PU41 R-GGA-159868 https://reactome.org/PathwayBrowser/#/R-GGA-159868 Furin cleaves pro-factor VII to factor VII IEA Gallus gallus A0A1D5PU53 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PU53 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1D5PU53 R-GGA-6807877 https://reactome.org/PathwayBrowser/#/R-GGA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Gallus gallus A0A1D5PU53 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1D5PU53 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1D5PU53 R-GGA-6809011 https://reactome.org/PathwayBrowser/#/R-GGA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Gallus gallus A0A1D5PU53 R-GGA-977619 https://reactome.org/PathwayBrowser/#/R-GGA-977619 CD55 (DAF) promotes C3bBb/C4bC2a dissociation IEA Gallus gallus A0A1D5PU53 R-GGA-981535 https://reactome.org/PathwayBrowser/#/R-GGA-981535 CD55 (DAF) binds C3bBb, C4bC2a IEA Gallus gallus A0A1D5PU80 R-GGA-936897 https://reactome.org/PathwayBrowser/#/R-GGA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Gallus gallus A0A1D5PU80 R-GGA-9684068 https://reactome.org/PathwayBrowser/#/R-GGA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Gallus gallus A0A1D5PU85 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1D5PU85 R-GGA-388560 https://reactome.org/PathwayBrowser/#/R-GGA-388560 EDNRA,EDNRB bind EDNs IEA Gallus gallus A0A1D5PU85 R-GGA-5694082 https://reactome.org/PathwayBrowser/#/R-GGA-5694082 XK:KEL:Zn2+ cleaves EDN3 IEA Gallus gallus A0A1D5PU85 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1D5PU85 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1D5PU85 R-GGA-9731924 https://reactome.org/PathwayBrowser/#/R-GGA-9731924 EDNRA binds EDNs IEA Gallus gallus A0A1D5PU92 R-GGA-418553 https://reactome.org/PathwayBrowser/#/R-GGA-418553 cAMP degradation by Phosphodiesterases IEA Gallus gallus A0A1D5PU96 R-GGA-5653766 https://reactome.org/PathwayBrowser/#/R-GGA-5653766 USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Gallus gallus A0A1D5PU96 R-GGA-5653770 https://reactome.org/PathwayBrowser/#/R-GGA-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Gallus gallus A0A1D5PU96 R-GGA-6781779 https://reactome.org/PathwayBrowser/#/R-GGA-6781779 USP13 deubiquitinates BECN1,USP10 IEA Gallus gallus A0A1D5PU96 R-GGA-6782106 https://reactome.org/PathwayBrowser/#/R-GGA-6782106 USP10 deubiquitinates SNX3, CFTR IEA Gallus gallus A0A1D5PUA4 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PUA4 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PUA4 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PUA4 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PUA8 R-GGA-913675 https://reactome.org/PathwayBrowser/#/R-GGA-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Gallus gallus A0A1D5PUB0 R-GGA-6791222 https://reactome.org/PathwayBrowser/#/R-GGA-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Gallus gallus A0A1D5PUB0 R-GGA-6791227 https://reactome.org/PathwayBrowser/#/R-GGA-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Gallus gallus A0A1D5PUB7 R-GGA-75885 https://reactome.org/PathwayBrowser/#/R-GGA-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Gallus gallus A0A1D5PUB7 R-GGA-8849345 https://reactome.org/PathwayBrowser/#/R-GGA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Gallus gallus A0A1D5PUD5 R-GGA-111439 https://reactome.org/PathwayBrowser/#/R-GGA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Gallus gallus A0A1D5PUD5 R-GGA-158441 https://reactome.org/PathwayBrowser/#/R-GGA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PUD5 R-GGA-158447 https://reactome.org/PathwayBrowser/#/R-GGA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Gallus gallus A0A1D5PUD5 R-GGA-158481 https://reactome.org/PathwayBrowser/#/R-GGA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PUD5 R-GGA-158484 https://reactome.org/PathwayBrowser/#/R-GGA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Gallus gallus A0A1D5PUD5 R-GGA-159046 https://reactome.org/PathwayBrowser/#/R-GGA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Gallus gallus A0A1D5PUD5 R-GGA-159050 https://reactome.org/PathwayBrowser/#/R-GGA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Gallus gallus A0A1D5PUD5 R-GGA-170825 https://reactome.org/PathwayBrowser/#/R-GGA-170825 NPC exports GCK1 from nucleus IEA Gallus gallus A0A1D5PUD5 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1D5PUD5 R-GGA-2990880 https://reactome.org/PathwayBrowser/#/R-GGA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Gallus gallus A0A1D5PUD5 R-GGA-2990882 https://reactome.org/PathwayBrowser/#/R-GGA-2990882 CDK1 phosphorylates NUP98 IEA Gallus gallus A0A1D5PUD5 R-GGA-4551649 https://reactome.org/PathwayBrowser/#/R-GGA-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Gallus gallus A0A1D5PUD5 R-GGA-4551679 https://reactome.org/PathwayBrowser/#/R-GGA-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Gallus gallus A0A1D5PUD5 R-GGA-4615872 https://reactome.org/PathwayBrowser/#/R-GGA-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Gallus gallus A0A1D5PUD5 R-GGA-4615987 https://reactome.org/PathwayBrowser/#/R-GGA-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Gallus gallus A0A1D5PUD5 R-GGA-4655355 https://reactome.org/PathwayBrowser/#/R-GGA-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Gallus gallus A0A1D5PUD5 R-GGA-5228523 https://reactome.org/PathwayBrowser/#/R-GGA-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Gallus gallus A0A1D5PUD5 R-GGA-5578744 https://reactome.org/PathwayBrowser/#/R-GGA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Gallus gallus A0A1D5PUD5 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1D5PUD5 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1D5PUD5 R-GGA-77587 https://reactome.org/PathwayBrowser/#/R-GGA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Gallus gallus A0A1D5PUF0 R-GGA-266012 https://reactome.org/PathwayBrowser/#/R-GGA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Gallus gallus A0A1D5PUF0 R-GGA-5433067 https://reactome.org/PathwayBrowser/#/R-GGA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG IEA Gallus gallus A0A1D5PUF7 R-GGA-6787623 https://reactome.org/PathwayBrowser/#/R-GGA-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal IEA Gallus gallus A0A1D5PUF7 R-GGA-6787642 https://reactome.org/PathwayBrowser/#/R-GGA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Gallus gallus A0A1D5PUG2 R-GGA-6797913 https://reactome.org/PathwayBrowser/#/R-GGA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Gallus gallus A0A1D5PUG6 R-GGA-75079 https://reactome.org/PathwayBrowser/#/R-GGA-75079 Formation of AT-AC C complex IEA Gallus gallus A0A1D5PUG6 R-GGA-75081 https://reactome.org/PathwayBrowser/#/R-GGA-75081 Formation of AT-AC B Complex IEA Gallus gallus A0A1D5PUG6 R-GGA-75082 https://reactome.org/PathwayBrowser/#/R-GGA-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Gallus gallus A0A1D5PUG6 R-GGA-75083 https://reactome.org/PathwayBrowser/#/R-GGA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Gallus gallus A0A1D5PUG9 R-GGA-199299 https://reactome.org/PathwayBrowser/#/R-GGA-199299 AKT phosphorylates FOXO transcription factors IEA Gallus gallus A0A1D5PUG9 R-GGA-211164 https://reactome.org/PathwayBrowser/#/R-GGA-211164 AKT phosphorylates FOXO1A IEA Gallus gallus A0A1D5PUG9 R-GGA-211178 https://reactome.org/PathwayBrowser/#/R-GGA-211178 Phosphorylated FOXO1A is excluded from the nucleus IEA Gallus gallus A0A1D5PUG9 R-GGA-5692779 https://reactome.org/PathwayBrowser/#/R-GGA-5692779 p-T182 MAPKAPK5 phosphorylates FOXO1 IEA Gallus gallus A0A1D5PUG9 R-GGA-9614414 https://reactome.org/PathwayBrowser/#/R-GGA-9614414 AKT-phosphorylated FOXO1,FOXO3,FOXO4 translocate to the cytosol IEA Gallus gallus A0A1D5PUG9 R-GGA-9614423 https://reactome.org/PathwayBrowser/#/R-GGA-9614423 14-3-3 proteins bind AKT-phosphorylated FOXO1 IEA Gallus gallus A0A1D5PUG9 R-GGA-9618021 https://reactome.org/PathwayBrowser/#/R-GGA-9618021 FOXG1 binds FOXO:SMAD complexes IEA Gallus gallus A0A1D5PUG9 R-GGA-9626928 https://reactome.org/PathwayBrowser/#/R-GGA-9626928 CREBBP binds FOXO1 IEA Gallus gallus A0A1D5PUH1 R-GGA-376419 https://reactome.org/PathwayBrowser/#/R-GGA-376419 Formation of NR-MED1 Coactivator Complex IEA Gallus gallus A0A1D5PUH1 R-GGA-382096 https://reactome.org/PathwayBrowser/#/R-GGA-382096 Formation of NR-NCOR Corepressor Complex IEA Gallus gallus A0A1D5PUH1 R-GGA-4755494 https://reactome.org/PathwayBrowser/#/R-GGA-4755494 PIAS1,2-1 SUMOylate NR5A2 with SUMO1 IEA Gallus gallus A0A1D5PUH1 R-GGA-9012000 https://reactome.org/PathwayBrowser/#/R-GGA-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Gallus gallus A0A1D5PUI6 R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus A0A1D5PUI6 R-GGA-9709406 https://reactome.org/PathwayBrowser/#/R-GGA-9709406 CO binds to Cytochrome c oxidase IEA Gallus gallus A0A1D5PUI6 R-GGA-9837978 https://reactome.org/PathwayBrowser/#/R-GGA-9837978 LONP1 binds mitochondrial inner membrane proteins IEA Gallus gallus A0A1D5PUI6 R-GGA-9838004 https://reactome.org/PathwayBrowser/#/R-GGA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Gallus gallus A0A1D5PUJ5 R-GGA-141423 https://reactome.org/PathwayBrowser/#/R-GGA-141423 Binding of the MCC complex to the APC/C complex IEA Gallus gallus A0A1D5PUJ5 R-GGA-174057 https://reactome.org/PathwayBrowser/#/R-GGA-174057 Multiubiquitination of APC/C-associated Cdh1 IEA Gallus gallus A0A1D5PUJ5 R-GGA-174058 https://reactome.org/PathwayBrowser/#/R-GGA-174058 Degradation of multiubiquitinated Cdh1 IEA Gallus gallus A0A1D5PUJ5 R-GGA-174070 https://reactome.org/PathwayBrowser/#/R-GGA-174070 Association of Cdh1 with the APC/C IEA Gallus gallus A0A1D5PUJ5 R-GGA-174079 https://reactome.org/PathwayBrowser/#/R-GGA-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Gallus gallus A0A1D5PUJ5 R-GGA-174088 https://reactome.org/PathwayBrowser/#/R-GGA-174088 Association of cell cycle proteins with the APC/C:Cdh1 complex IEA Gallus gallus A0A1D5PUJ5 R-GGA-174104 https://reactome.org/PathwayBrowser/#/R-GGA-174104 Ubiquitination of Cyclin A by APC/C:Cdc20 complex IEA Gallus gallus A0A1D5PUJ5 R-GGA-174105 https://reactome.org/PathwayBrowser/#/R-GGA-174105 Degradation of multiubiquitinated cell cycle proteins IEA Gallus gallus A0A1D5PUJ5 R-GGA-174119 https://reactome.org/PathwayBrowser/#/R-GGA-174119 Free APC/C phosphorylated by Plk1 IEA Gallus gallus A0A1D5PUJ5 R-GGA-174121 https://reactome.org/PathwayBrowser/#/R-GGA-174121 Association of Securin with Cdc20:APC/C complex IEA Gallus gallus A0A1D5PUJ5 R-GGA-174139 https://reactome.org/PathwayBrowser/#/R-GGA-174139 Dissociation of phospho-Cdh1 from the APC/C complex IEA Gallus gallus A0A1D5PUJ5 R-GGA-174144 https://reactome.org/PathwayBrowser/#/R-GGA-174144 Ubiquitination of Securin by phospho-APC/C:Cdc20 complex IEA Gallus gallus A0A1D5PUJ5 R-GGA-174157 https://reactome.org/PathwayBrowser/#/R-GGA-174157 Degradation of multiubiquitinated Cyclin B IEA Gallus gallus A0A1D5PUJ5 R-GGA-174171 https://reactome.org/PathwayBrowser/#/R-GGA-174171 Association of Cyclin A with the APC/C IEA Gallus gallus A0A1D5PUJ5 R-GGA-174195 https://reactome.org/PathwayBrowser/#/R-GGA-174195 Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex IEA Gallus gallus A0A1D5PUJ5 R-GGA-174202 https://reactome.org/PathwayBrowser/#/R-GGA-174202 Degradation of multiubiquitinated Securin IEA Gallus gallus A0A1D5PUJ5 R-GGA-174224 https://reactome.org/PathwayBrowser/#/R-GGA-174224 Dissociation of Cdc20 from APC/C complex IEA Gallus gallus A0A1D5PUJ5 R-GGA-174227 https://reactome.org/PathwayBrowser/#/R-GGA-174227 Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex IEA Gallus gallus A0A1D5PUJ5 R-GGA-174238 https://reactome.org/PathwayBrowser/#/R-GGA-174238 Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 IEA Gallus gallus A0A1D5PUJ5 R-GGA-174255 https://reactome.org/PathwayBrowser/#/R-GGA-174255 Degradation multiubiquitinated Cyclin A IEA Gallus gallus A0A1D5PUJ5 R-GGA-179410 https://reactome.org/PathwayBrowser/#/R-GGA-179410 Association of Nek2A with MCC:APC/C IEA Gallus gallus A0A1D5PUJ5 R-GGA-179417 https://reactome.org/PathwayBrowser/#/R-GGA-179417 Multiubiquitination of Nek2A IEA Gallus gallus A0A1D5PUJ5 R-GGA-179421 https://reactome.org/PathwayBrowser/#/R-GGA-179421 Degradation of multiubiquitinated Nek2A IEA Gallus gallus A0A1D5PUJ5 R-GGA-188191 https://reactome.org/PathwayBrowser/#/R-GGA-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Gallus gallus A0A1D5PUJ5 R-GGA-188371 https://reactome.org/PathwayBrowser/#/R-GGA-188371 Association of Cyclin A:Cdk2 with Cdh1 IEA Gallus gallus A0A1D5PUJ5 R-GGA-3788705 https://reactome.org/PathwayBrowser/#/R-GGA-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Gallus gallus A0A1D5PUJ5 R-GGA-3788708 https://reactome.org/PathwayBrowser/#/R-GGA-3788708 CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 IEA Gallus gallus A0A1D5PUJ5 R-GGA-3788724 https://reactome.org/PathwayBrowser/#/R-GGA-3788724 Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 IEA Gallus gallus A0A1D5PUJ5 R-GGA-68712 https://reactome.org/PathwayBrowser/#/R-GGA-68712 The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 IEA Gallus gallus A0A1D5PUJ5 R-GGA-69015 https://reactome.org/PathwayBrowser/#/R-GGA-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Gallus gallus A0A1D5PUJ5 R-GGA-9686969 https://reactome.org/PathwayBrowser/#/R-GGA-9686969 APC/C:Cdh1 polyubiquitinates SKP2 IEA Gallus gallus A0A1D5PUJ5 R-GGA-9686980 https://reactome.org/PathwayBrowser/#/R-GGA-9686980 RB1 recruits APC/C:Cdh1 complex to SKP2 IEA Gallus gallus A0A1D5PUJ6 R-GGA-182986 https://reactome.org/PathwayBrowser/#/R-GGA-182986 CBL-mediated ubiquitination of CIN85 IEA Gallus gallus A0A1D5PUJ6 R-GGA-182990 https://reactome.org/PathwayBrowser/#/R-GGA-182990 Sprouty sequesters CBL away from active EGFR IEA Gallus gallus A0A1D5PUJ6 R-GGA-6782628 https://reactome.org/PathwayBrowser/#/R-GGA-6782628 USP8 deubiquitinates STAM2:HGS IEA Gallus gallus A0A1D5PUJ6 R-GGA-8866279 https://reactome.org/PathwayBrowser/#/R-GGA-8866279 Epsin family proteins bind ubiquitinated cargo IEA Gallus gallus A0A1D5PUJ6 R-GGA-8867041 https://reactome.org/PathwayBrowser/#/R-GGA-8867041 EGFR phosphorylates EPS15 IEA Gallus gallus A0A1D5PUJ6 R-GGA-8867047 https://reactome.org/PathwayBrowser/#/R-GGA-8867047 PTPN3 dephosphorylates EPS15 IEA Gallus gallus A0A1D5PUJ6 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1D5PUJ6 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1D5PUJ6 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1D5PUJ6 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1D5PUJ6 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1D5PUJ6 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1D5PUJ6 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1D5PUJ6 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1D5PUJ6 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PUJ6 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1D5PUJ6 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1D5PUJ6 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1D5PUJ6 R-GGA-8875490 https://reactome.org/PathwayBrowser/#/R-GGA-8875490 EPS15 and HGS bind ubiquitinated MET IEA Gallus gallus A0A1D5PUJ6 R-GGA-9018766 https://reactome.org/PathwayBrowser/#/R-GGA-9018766 RHOU binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PUJ6 R-GGA-917730 https://reactome.org/PathwayBrowser/#/R-GGA-917730 Cargo Recognition And Sorting IEA Gallus gallus A0A1D5PUJ8 R-GGA-5173005 https://reactome.org/PathwayBrowser/#/R-GGA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Gallus gallus A0A1D5PUJ8 R-GGA-5173192 https://reactome.org/PathwayBrowser/#/R-GGA-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Gallus gallus A0A1D5PUL3 R-GGA-9708457 https://reactome.org/PathwayBrowser/#/R-GGA-9708457 HM13 cleaves HMOX1 dimer IEA Gallus gallus A0A1D5PUL8 R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus A0A1D5PUL8 R-GGA-204169 https://reactome.org/PathwayBrowser/#/R-GGA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Gallus gallus A0A1D5PUL8 R-GGA-9861616 https://reactome.org/PathwayBrowser/#/R-GGA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus A0A1D5PUL8 R-GGA-9861667 https://reactome.org/PathwayBrowser/#/R-GGA-9861667 DLAT trimer transfers acetyl to CoA IEA Gallus gallus A0A1D5PUL8 R-GGA-9861734 https://reactome.org/PathwayBrowser/#/R-GGA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Gallus gallus A0A1D5PUM1 R-GGA-5250930 https://reactome.org/PathwayBrowser/#/R-GGA-5250930 B-WICH recruits histone acetyltransferases IEA Gallus gallus A0A1D5PUM1 R-GGA-5250938 https://reactome.org/PathwayBrowser/#/R-GGA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Gallus gallus A0A1D5PUM1 R-GGA-5250947 https://reactome.org/PathwayBrowser/#/R-GGA-5250947 B-WICH complex binds rDNA promoter IEA Gallus gallus A0A1D5PUM4 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PUP4 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus A0A1D5PUQ7 R-GGA-70467 https://reactome.org/PathwayBrowser/#/R-GGA-70467 PFK tetramer phosphorylates Fru(6)P IEA Gallus gallus A0A1D5PUR0 R-GGA-1236943 https://reactome.org/PathwayBrowser/#/R-GGA-1236943 Loading of antigen peptide onto MHC class I molecule IEA Gallus gallus A0A1D5PUR0 R-GGA-1236954 https://reactome.org/PathwayBrowser/#/R-GGA-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Gallus gallus A0A1D5PUR0 R-GGA-1236964 https://reactome.org/PathwayBrowser/#/R-GGA-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Gallus gallus A0A1D5PUR0 R-GGA-1236965 https://reactome.org/PathwayBrowser/#/R-GGA-1236965 Export of peptide loaded MHC class I complex to PM IEA Gallus gallus A0A1D5PUR0 R-GGA-198955 https://reactome.org/PathwayBrowser/#/R-GGA-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Gallus gallus A0A1D5PUR0 R-GGA-199062 https://reactome.org/PathwayBrowser/#/R-GGA-199062 KLRC1:KLRD1 heterodimer interacts with HLA-E IEA Gallus gallus A0A1D5PUR0 R-GGA-210289 https://reactome.org/PathwayBrowser/#/R-GGA-210289 Recruitment of SYK to p-DAP12 IEA Gallus gallus A0A1D5PUR0 R-GGA-2395412 https://reactome.org/PathwayBrowser/#/R-GGA-2395412 Phosphorylation of SYK IEA Gallus gallus A0A1D5PUR0 R-GGA-2396594 https://reactome.org/PathwayBrowser/#/R-GGA-2396594 Phosphorylation of SLP-76 by p-SYK IEA Gallus gallus A0A1D5PUR0 R-GGA-2424480 https://reactome.org/PathwayBrowser/#/R-GGA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PUR0 R-GGA-2424482 https://reactome.org/PathwayBrowser/#/R-GGA-2424482 p85 regulatory unit of PI3K binds p-6Y-SYK IEA Gallus gallus A0A1D5PUR0 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus A0A1D5PUR0 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus A0A1D5PUR0 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus A0A1D5PUR0 R-GGA-5691154 https://reactome.org/PathwayBrowser/#/R-GGA-5691154 HFE binds TFRC dimer IEA Gallus gallus A0A1D5PUR0 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5PUR0 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PUR0 R-GGA-8863973 https://reactome.org/PathwayBrowser/#/R-GGA-8863973 Fusion of ERC and phagosome IEA Gallus gallus A0A1D5PUR0 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus A0A1D5PUR0 R-GGA-8951499 https://reactome.org/PathwayBrowser/#/R-GGA-8951499 Loading of antigenic peptides on to class I MHC IEA Gallus gallus A0A1D5PUR0 R-GGA-983138 https://reactome.org/PathwayBrowser/#/R-GGA-983138 Transport of MHC heterotrimer to ER exit site IEA Gallus gallus A0A1D5PUR0 R-GGA-983145 https://reactome.org/PathwayBrowser/#/R-GGA-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Gallus gallus A0A1D5PUR0 R-GGA-983146 https://reactome.org/PathwayBrowser/#/R-GGA-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Gallus gallus A0A1D5PUR0 R-GGA-983421 https://reactome.org/PathwayBrowser/#/R-GGA-983421 Journey of cargo through Golgi complex IEA Gallus gallus A0A1D5PUR0 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus A0A1D5PUR0 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus A0A1D5PUR0 R-GGA-983425 https://reactome.org/PathwayBrowser/#/R-GGA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Gallus gallus A0A1D5PUR0 R-GGA-983427 https://reactome.org/PathwayBrowser/#/R-GGA-983427 Expression of peptide bound class I MHC on cell surface IEA Gallus gallus A0A1D5PUS3 R-GGA-2022052 https://reactome.org/PathwayBrowser/#/R-GGA-2022052 Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS) IEA Gallus gallus A0A1D5PUW8 R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus A0A1D5PUW8 R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus A0A1D5PUW8 R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus A0A1D5PUW8 R-GGA-9018806 https://reactome.org/PathwayBrowser/#/R-GGA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Gallus gallus A0A1D5PUY5 R-GGA-114553 https://reactome.org/PathwayBrowser/#/R-GGA-114553 Activation of conventional Protein Kinase C IEA Gallus gallus A0A1D5PUY5 R-GGA-114683 https://reactome.org/PathwayBrowser/#/R-GGA-114683 Phosphorylation of Platelet Sec-1 IEA Gallus gallus A0A1D5PUY5 R-GGA-1168373 https://reactome.org/PathwayBrowser/#/R-GGA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Gallus gallus A0A1D5PUY5 R-GGA-1168635 https://reactome.org/PathwayBrowser/#/R-GGA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Gallus gallus A0A1D5PUY5 R-GGA-416639 https://reactome.org/PathwayBrowser/#/R-GGA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Gallus gallus A0A1D5PUY5 R-GGA-421007 https://reactome.org/PathwayBrowser/#/R-GGA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Gallus gallus A0A1D5PUY5 R-GGA-5218805 https://reactome.org/PathwayBrowser/#/R-GGA-5218805 PKC autophosphorylates IEA Gallus gallus A0A1D5PUY5 R-GGA-5218813 https://reactome.org/PathwayBrowser/#/R-GGA-5218813 DAG and Ca+2 bind to PKC and tether it to membrane IEA Gallus gallus A0A1D5PUY5 R-GGA-5218821 https://reactome.org/PathwayBrowser/#/R-GGA-5218821 PDK1 phosphorylates PKC IEA Gallus gallus A0A1D5PUY5 R-GGA-5218823 https://reactome.org/PathwayBrowser/#/R-GGA-5218823 PKC phosphorylates sphingosine kinase 1 IEA Gallus gallus A0A1D5PUY5 R-GGA-5223304 https://reactome.org/PathwayBrowser/#/R-GGA-5223304 DAG and Ca+2 bind to PKC and tether it to membrane IEA Gallus gallus A0A1D5PUY5 R-GGA-9626817 https://reactome.org/PathwayBrowser/#/R-GGA-9626817 PKC phosphorylates NCF1 IEA Gallus gallus A0A1D5PUZ4 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus A0A1D5PUZ4 R-GGA-9640237 https://reactome.org/PathwayBrowser/#/R-GGA-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Gallus gallus A0A1D5PUZ5 R-GGA-188979 https://reactome.org/PathwayBrowser/#/R-GGA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Gallus gallus A0A1D5PUZ5 R-GGA-191114 https://reactome.org/PathwayBrowser/#/R-GGA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Gallus gallus A0A1D5PV09 R-GGA-2029465 https://reactome.org/PathwayBrowser/#/R-GGA-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Gallus gallus A0A1D5PV09 R-GGA-2029466 https://reactome.org/PathwayBrowser/#/R-GGA-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Gallus gallus A0A1D5PV09 R-GGA-2029469 https://reactome.org/PathwayBrowser/#/R-GGA-2029469 p-ERK phosphorylates WAVEs and ABI IEA Gallus gallus A0A1D5PV09 R-GGA-2130194 https://reactome.org/PathwayBrowser/#/R-GGA-2130194 ABL phosphorylates WAVEs IEA Gallus gallus A0A1D5PV09 R-GGA-2197690 https://reactome.org/PathwayBrowser/#/R-GGA-2197690 Detachment of WASP/WAVE IEA Gallus gallus A0A1D5PV09 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PV09 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1D5PV09 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PV09 R-GGA-9014294 https://reactome.org/PathwayBrowser/#/R-GGA-9014294 RAC2 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PV09 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PV10 R-GGA-3364026 https://reactome.org/PathwayBrowser/#/R-GGA-3364026 SET1 complex trimethylates H3K4 at the MYC gene IEA Gallus gallus A0A1D5PV10 R-GGA-8936481 https://reactome.org/PathwayBrowser/#/R-GGA-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Gallus gallus A0A1D5PV10 R-GGA-8936621 https://reactome.org/PathwayBrowser/#/R-GGA-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Gallus gallus A0A1D5PV10 R-GGA-8937016 https://reactome.org/PathwayBrowser/#/R-GGA-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Gallus gallus A0A1D5PV10 R-GGA-8937050 https://reactome.org/PathwayBrowser/#/R-GGA-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Gallus gallus A0A1D5PV10 R-GGA-9676268 https://reactome.org/PathwayBrowser/#/R-GGA-9676268 Formation of the MLL4 complex IEA Gallus gallus A0A1D5PV14 R-GGA-1236943 https://reactome.org/PathwayBrowser/#/R-GGA-1236943 Loading of antigen peptide onto MHC class I molecule IEA Gallus gallus A0A1D5PV14 R-GGA-1236954 https://reactome.org/PathwayBrowser/#/R-GGA-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Gallus gallus A0A1D5PV14 R-GGA-1236964 https://reactome.org/PathwayBrowser/#/R-GGA-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Gallus gallus A0A1D5PV14 R-GGA-1236965 https://reactome.org/PathwayBrowser/#/R-GGA-1236965 Export of peptide loaded MHC class I complex to PM IEA Gallus gallus A0A1D5PV14 R-GGA-198955 https://reactome.org/PathwayBrowser/#/R-GGA-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Gallus gallus A0A1D5PV14 R-GGA-199062 https://reactome.org/PathwayBrowser/#/R-GGA-199062 KLRC1:KLRD1 heterodimer interacts with HLA-E IEA Gallus gallus A0A1D5PV14 R-GGA-210289 https://reactome.org/PathwayBrowser/#/R-GGA-210289 Recruitment of SYK to p-DAP12 IEA Gallus gallus A0A1D5PV14 R-GGA-2395412 https://reactome.org/PathwayBrowser/#/R-GGA-2395412 Phosphorylation of SYK IEA Gallus gallus A0A1D5PV14 R-GGA-2396594 https://reactome.org/PathwayBrowser/#/R-GGA-2396594 Phosphorylation of SLP-76 by p-SYK IEA Gallus gallus A0A1D5PV14 R-GGA-2424480 https://reactome.org/PathwayBrowser/#/R-GGA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PV14 R-GGA-2424482 https://reactome.org/PathwayBrowser/#/R-GGA-2424482 p85 regulatory unit of PI3K binds p-6Y-SYK IEA Gallus gallus A0A1D5PV14 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus A0A1D5PV14 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus A0A1D5PV14 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus A0A1D5PV14 R-GGA-5691154 https://reactome.org/PathwayBrowser/#/R-GGA-5691154 HFE binds TFRC dimer IEA Gallus gallus A0A1D5PV14 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5PV14 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PV14 R-GGA-8863973 https://reactome.org/PathwayBrowser/#/R-GGA-8863973 Fusion of ERC and phagosome IEA Gallus gallus A0A1D5PV14 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus A0A1D5PV14 R-GGA-8951499 https://reactome.org/PathwayBrowser/#/R-GGA-8951499 Loading of antigenic peptides on to class I MHC IEA Gallus gallus A0A1D5PV14 R-GGA-983138 https://reactome.org/PathwayBrowser/#/R-GGA-983138 Transport of MHC heterotrimer to ER exit site IEA Gallus gallus A0A1D5PV14 R-GGA-983145 https://reactome.org/PathwayBrowser/#/R-GGA-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Gallus gallus A0A1D5PV14 R-GGA-983146 https://reactome.org/PathwayBrowser/#/R-GGA-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Gallus gallus A0A1D5PV14 R-GGA-983421 https://reactome.org/PathwayBrowser/#/R-GGA-983421 Journey of cargo through Golgi complex IEA Gallus gallus A0A1D5PV14 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus A0A1D5PV14 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus A0A1D5PV14 R-GGA-983425 https://reactome.org/PathwayBrowser/#/R-GGA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Gallus gallus A0A1D5PV14 R-GGA-983427 https://reactome.org/PathwayBrowser/#/R-GGA-983427 Expression of peptide bound class I MHC on cell surface IEA Gallus gallus A0A1D5PV21 R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus A0A1D5PV21 R-GGA-9709406 https://reactome.org/PathwayBrowser/#/R-GGA-9709406 CO binds to Cytochrome c oxidase IEA Gallus gallus A0A1D5PV53 R-GGA-1483203 https://reactome.org/PathwayBrowser/#/R-GGA-1483203 PA is dephosphorylated to DAG by LPIN IEA Gallus gallus A0A1D5PV53 R-GGA-5221130 https://reactome.org/PathwayBrowser/#/R-GGA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Gallus gallus A0A1D5PV53 R-GGA-75899 https://reactome.org/PathwayBrowser/#/R-GGA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Gallus gallus A0A1D5PV61 R-GGA-352268 https://reactome.org/PathwayBrowser/#/R-GGA-352268 Cleavage of Satb1 IEA Gallus gallus A0A1D5PV61 R-GGA-4615839 https://reactome.org/PathwayBrowser/#/R-GGA-4615839 PIAS1 SUMOylates SATB1 with SUMO2,3 IEA Gallus gallus A0A1D5PV61 R-GGA-4615905 https://reactome.org/PathwayBrowser/#/R-GGA-4615905 PIAS1 SUMOylates SATB1 with SUMO1 IEA Gallus gallus A0A1D5PV69 R-GGA-176298 https://reactome.org/PathwayBrowser/#/R-GGA-176298 Activation of claspin IEA Gallus gallus A0A1D5PV69 R-GGA-176318 https://reactome.org/PathwayBrowser/#/R-GGA-176318 Loading of claspin onto DNA during replication origin firing IEA Gallus gallus A0A1D5PV69 R-GGA-68914 https://reactome.org/PathwayBrowser/#/R-GGA-68914 DNA polymerase alpha:primase binds at the origin IEA Gallus gallus A0A1D5PV69 R-GGA-68916 https://reactome.org/PathwayBrowser/#/R-GGA-68916 DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin IEA Gallus gallus A0A1D5PV69 R-GGA-68917 https://reactome.org/PathwayBrowser/#/R-GGA-68917 Cdc45 associates with the pre-replicative complex at the origin IEA Gallus gallus A0A1D5PV69 R-GGA-68918 https://reactome.org/PathwayBrowser/#/R-GGA-68918 CDK and DDK associate with the Mcm10:pre-replicative complex IEA Gallus gallus A0A1D5PV69 R-GGA-68919 https://reactome.org/PathwayBrowser/#/R-GGA-68919 Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 IEA Gallus gallus A0A1D5PV69 R-GGA-68940 https://reactome.org/PathwayBrowser/#/R-GGA-68940 Cdt1 is displaced from the pre-replicative complex IEA Gallus gallus A0A1D5PV69 R-GGA-68960 https://reactome.org/PathwayBrowser/#/R-GGA-68960 DNA polymerase epsilon binds at the origin IEA Gallus gallus A0A1D5PV80 R-GGA-9696266 https://reactome.org/PathwayBrowser/#/R-GGA-9696266 RND2 binds effectors IEA Gallus gallus A0A1D5PV80 R-GGA-9696268 https://reactome.org/PathwayBrowser/#/R-GGA-9696268 RND3 binds effectors IEA Gallus gallus A0A1D5PV80 R-GGA-9696271 https://reactome.org/PathwayBrowser/#/R-GGA-9696271 RND1 binds effectors IEA Gallus gallus A0A1D5PV96 R-GGA-1675776 https://reactome.org/PathwayBrowser/#/R-GGA-1675776 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane IEA Gallus gallus A0A1D5PV96 R-GGA-1676145 https://reactome.org/PathwayBrowser/#/R-GGA-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Gallus gallus A0A1D5PV96 R-GGA-6811522 https://reactome.org/PathwayBrowser/#/R-GGA-6811522 PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus IEA Gallus gallus A0A1D5PV96 R-GGA-8877691 https://reactome.org/PathwayBrowser/#/R-GGA-8877691 MAP2K6 phosphorylates PIP4K2B IEA Gallus gallus A0A1D5PV96 R-GGA-8877692 https://reactome.org/PathwayBrowser/#/R-GGA-8877692 PIN1 binds phosphorylated PIP4K2B IEA Gallus gallus A0A1D5PVB3 R-GGA-177926 https://reactome.org/PathwayBrowser/#/R-GGA-177926 Dephosphorylation of PAG by SHP2 IEA Gallus gallus A0A1D5PVB3 R-GGA-202233 https://reactome.org/PathwayBrowser/#/R-GGA-202233 Inactivation of Lck by Csk IEA Gallus gallus A0A1D5PVB3 R-GGA-203774 https://reactome.org/PathwayBrowser/#/R-GGA-203774 Interaction of Csk with PAG IEA Gallus gallus A0A1D5PVB6 R-GGA-427605 https://reactome.org/PathwayBrowser/#/R-GGA-427605 SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol IEA Gallus gallus A0A1D5PVC1 R-GGA-5687097 https://reactome.org/PathwayBrowser/#/R-GGA-5687097 p-S857 NCOA3 binds ETV4 IEA Gallus gallus A0A1D5PVC4 R-GGA-429955 https://reactome.org/PathwayBrowser/#/R-GGA-429955 CCR4-NOT complex deadenylates mRNA IEA Gallus gallus A0A1D5PVC4 R-GGA-6798044 https://reactome.org/PathwayBrowser/#/R-GGA-6798044 BTG2 binds CCR4-NOT complex IEA Gallus gallus A0A1D5PVD2 R-GGA-1454791 https://reactome.org/PathwayBrowser/#/R-GGA-1454791 MMP2, MMP7, MMP9 bind CD44 IEA Gallus gallus A0A1D5PVD2 R-GGA-2160884 https://reactome.org/PathwayBrowser/#/R-GGA-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ IEA Gallus gallus A0A1D5PVD2 R-GGA-2160892 https://reactome.org/PathwayBrowser/#/R-GGA-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments IEA Gallus gallus A0A1D5PVD2 R-GGA-2160915 https://reactome.org/PathwayBrowser/#/R-GGA-2160915 Receptor-mediated uptake of HA IEA Gallus gallus A0A1D5PVD2 R-GGA-2752115 https://reactome.org/PathwayBrowser/#/R-GGA-2752115 SPP1 (osteopontin) binds CD44 IEA Gallus gallus A0A1D5PVD2 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PVF3 R-GGA-6814555 https://reactome.org/PathwayBrowser/#/R-GGA-6814555 Integrator complex processes the 3' end of snRNA IEA Gallus gallus A0A1D5PVF3 R-GGA-6814559 https://reactome.org/PathwayBrowser/#/R-GGA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Gallus gallus A0A1D5PVF7 R-GGA-5626938 https://reactome.org/PathwayBrowser/#/R-GGA-5626938 Beta-catenin binds SOX proteins IEA Gallus gallus A0A1D5PVF8 R-GGA-196950 https://reactome.org/PathwayBrowser/#/R-GGA-196950 2xTRAP hydrolyzes FMN to RIB IEA Gallus gallus A0A1D5PVG5 R-GGA-5173005 https://reactome.org/PathwayBrowser/#/R-GGA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Gallus gallus A0A1D5PVG5 R-GGA-5173192 https://reactome.org/PathwayBrowser/#/R-GGA-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Gallus gallus A0A1D5PVG8 R-GGA-158251 https://reactome.org/PathwayBrowser/#/R-GGA-158251 prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer IEA Gallus gallus A0A1D5PVG8 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5PVG8 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1D5PVH5 R-GGA-72103 https://reactome.org/PathwayBrowser/#/R-GGA-72103 Formation of pre-mRNPs IEA Gallus gallus A0A1D5PVH5 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5PVH7 R-GGA-2404193 https://reactome.org/PathwayBrowser/#/R-GGA-2404193 IGF1R phosphorylates SHC1 IEA Gallus gallus A0A1D5PVH7 R-GGA-2404195 https://reactome.org/PathwayBrowser/#/R-GGA-2404195 IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 IEA Gallus gallus A0A1D5PVH7 R-GGA-2404199 https://reactome.org/PathwayBrowser/#/R-GGA-2404199 IGF1,2:IGF1R autophosphorylates IEA Gallus gallus A0A1D5PVH7 R-GGA-2404200 https://reactome.org/PathwayBrowser/#/R-GGA-2404200 IGF1,2 binds IGF1R IEA Gallus gallus A0A1D5PVH7 R-GGA-2428926 https://reactome.org/PathwayBrowser/#/R-GGA-2428926 IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 IEA Gallus gallus A0A1D5PVH7 R-GGA-2428930 https://reactome.org/PathwayBrowser/#/R-GGA-2428930 IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS1,4 IEA Gallus gallus A0A1D5PVH7 R-GGA-5686072 https://reactome.org/PathwayBrowser/#/R-GGA-5686072 p-3Y-SHC1 dissociates from IGF1R IEA Gallus gallus A0A1D5PVH7 R-GGA-9624272 https://reactome.org/PathwayBrowser/#/R-GGA-9624272 MMPs cleave HB-EGF IEA Gallus gallus A0A1D5PVH7 R-GGA-9634584 https://reactome.org/PathwayBrowser/#/R-GGA-9634584 Estrogen receptor binds IGF1R and SHC1 in response to estrogen IEA Gallus gallus A0A1D5PVL3 R-GGA-444120 https://reactome.org/PathwayBrowser/#/R-GGA-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Gallus gallus A0A1D5PVL4 R-GGA-156808 https://reactome.org/PathwayBrowser/#/R-GGA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Gallus gallus A0A1D5PVL4 R-GGA-157849 https://reactome.org/PathwayBrowser/#/R-GGA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Gallus gallus A0A1D5PVL4 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus A0A1D5PVL4 R-GGA-72676 https://reactome.org/PathwayBrowser/#/R-GGA-72676 eIF3 and eIF1A bind to the 40S subunit IEA Gallus gallus A0A1D5PVL4 R-GGA-72691 https://reactome.org/PathwayBrowser/#/R-GGA-72691 Formation of the 43S pre-initiation complex IEA Gallus gallus A0A1D5PVL4 R-GGA-72697 https://reactome.org/PathwayBrowser/#/R-GGA-72697 Start codon recognition IEA Gallus gallus A0A1D5PVM0 R-GGA-174786 https://reactome.org/PathwayBrowser/#/R-GGA-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex IEA Gallus gallus A0A1D5PVM0 R-GGA-8866329 https://reactome.org/PathwayBrowser/#/R-GGA-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Gallus gallus A0A1D5PVM0 R-GGA-9737780 https://reactome.org/PathwayBrowser/#/R-GGA-9737780 MTTP binds lomitapide IEA Gallus gallus A0A1D5PVM5 R-GGA-156808 https://reactome.org/PathwayBrowser/#/R-GGA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Gallus gallus A0A1D5PVM5 R-GGA-157849 https://reactome.org/PathwayBrowser/#/R-GGA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Gallus gallus A0A1D5PVM5 R-GGA-1678842 https://reactome.org/PathwayBrowser/#/R-GGA-1678842 Competitive inhibition of translation initiation by ISGylated 4EHP IEA Gallus gallus A0A1D5PVM5 R-GGA-429955 https://reactome.org/PathwayBrowser/#/R-GGA-429955 CCR4-NOT complex deadenylates mRNA IEA Gallus gallus A0A1D5PVM5 R-GGA-429992 https://reactome.org/PathwayBrowser/#/R-GGA-429992 PARN deadenylates mRNA IEA Gallus gallus A0A1D5PVM5 R-GGA-430021 https://reactome.org/PathwayBrowser/#/R-GGA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Gallus gallus A0A1D5PVM5 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus A0A1D5PVM5 R-GGA-72697 https://reactome.org/PathwayBrowser/#/R-GGA-72697 Start codon recognition IEA Gallus gallus A0A1D5PVN3 R-GGA-5336453 https://reactome.org/PathwayBrowser/#/R-GGA-5336453 NIPAs transport Mg2+ from extracellular region to cytosol IEA Gallus gallus A0A1D5PVP0 R-GGA-1236398 https://reactome.org/PathwayBrowser/#/R-GGA-1236398 ERBB4 binds NRGs or EGF-like ligands IEA Gallus gallus A0A1D5PVP0 R-GGA-1247497 https://reactome.org/PathwayBrowser/#/R-GGA-1247497 ERBB3 binds neuregulins IEA Gallus gallus A0A1D5PVP0 R-GGA-1250189 https://reactome.org/PathwayBrowser/#/R-GGA-1250189 Binding of PI3K to ERBB2:p-ERBB3 heterodimer IEA Gallus gallus A0A1D5PVP0 R-GGA-1250195 https://reactome.org/PathwayBrowser/#/R-GGA-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Gallus gallus A0A1D5PVP0 R-GGA-1250220 https://reactome.org/PathwayBrowser/#/R-GGA-1250220 Homodimerization of ERBB4 IEA Gallus gallus A0A1D5PVP0 R-GGA-1250315 https://reactome.org/PathwayBrowser/#/R-GGA-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Gallus gallus A0A1D5PVP0 R-GGA-1250346 https://reactome.org/PathwayBrowser/#/R-GGA-1250346 Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers IEA Gallus gallus A0A1D5PVP0 R-GGA-1250348 https://reactome.org/PathwayBrowser/#/R-GGA-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Gallus gallus A0A1D5PVP0 R-GGA-1250353 https://reactome.org/PathwayBrowser/#/R-GGA-1250353 Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers IEA Gallus gallus A0A1D5PVP0 R-GGA-1250357 https://reactome.org/PathwayBrowser/#/R-GGA-1250357 SHC1 binds P-ERBB4 isoform dimers IEA Gallus gallus A0A1D5PVP0 R-GGA-1250370 https://reactome.org/PathwayBrowser/#/R-GGA-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Gallus gallus A0A1D5PVP0 R-GGA-1250380 https://reactome.org/PathwayBrowser/#/R-GGA-1250380 Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers IEA Gallus gallus A0A1D5PVP0 R-GGA-1250383 https://reactome.org/PathwayBrowser/#/R-GGA-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Gallus gallus A0A1D5PVP0 R-GGA-1250462 https://reactome.org/PathwayBrowser/#/R-GGA-1250462 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 IEA Gallus gallus A0A1D5PVP0 R-GGA-1306969 https://reactome.org/PathwayBrowser/#/R-GGA-1306969 GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers IEA Gallus gallus A0A1D5PVP0 R-GGA-1306972 https://reactome.org/PathwayBrowser/#/R-GGA-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Gallus gallus A0A1D5PVP0 R-GGA-1306979 https://reactome.org/PathwayBrowser/#/R-GGA-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Gallus gallus A0A1D5PVP0 R-GGA-1358792 https://reactome.org/PathwayBrowser/#/R-GGA-1358792 RNF41 ubiquitinates activated ERBB3 IEA Gallus gallus A0A1D5PVP0 R-GGA-1358798 https://reactome.org/PathwayBrowser/#/R-GGA-1358798 RNF41 binds neuregulin-activated ERBB3 IEA Gallus gallus A0A1D5PVP0 R-GGA-1963563 https://reactome.org/PathwayBrowser/#/R-GGA-1963563 MATK (CSK homologous kinase) binds phosphorylated ERBB2 IEA Gallus gallus A0A1D5PVP0 R-GGA-1963581 https://reactome.org/PathwayBrowser/#/R-GGA-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Gallus gallus A0A1D5PVP0 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus A0A1D5PVP0 R-GGA-1963586 https://reactome.org/PathwayBrowser/#/R-GGA-1963586 SRC family kinases phosphorylate ERBB2 IEA Gallus gallus A0A1D5PVP0 R-GGA-1977958 https://reactome.org/PathwayBrowser/#/R-GGA-1977958 ERBB4 forms heterodimers with ERBB3 IEA Gallus gallus A0A1D5PVP0 R-GGA-1977959 https://reactome.org/PathwayBrowser/#/R-GGA-1977959 ERBB4 forms heterodimers with EGFR IEA Gallus gallus A0A1D5PVP0 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PVP0 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5PVP0 R-GGA-6785636 https://reactome.org/PathwayBrowser/#/R-GGA-6785636 Phosphorylated ERBB2 heterodimers bind MEMO1 IEA Gallus gallus A0A1D5PVP0 R-GGA-8863804 https://reactome.org/PathwayBrowser/#/R-GGA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Gallus gallus A0A1D5PVQ2 R-GGA-6801328 https://reactome.org/PathwayBrowser/#/R-GGA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF IEA Gallus gallus A0A1D5PVQ2 R-GGA-6801462 https://reactome.org/PathwayBrowser/#/R-GGA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Gallus gallus A0A1D5PVQ4 R-GGA-110137 https://reactome.org/PathwayBrowser/#/R-GGA-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Gallus gallus A0A1D5PVQ4 R-GGA-110138 https://reactome.org/PathwayBrowser/#/R-GGA-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Gallus gallus A0A1D5PVR1 R-GGA-200652 https://reactome.org/PathwayBrowser/#/R-GGA-200652 SLC19A1 transports 5-methyl-THF from extracellular region to cytosol IEA Gallus gallus A0A1D5PVR6 R-GGA-8870457 https://reactome.org/PathwayBrowser/#/R-GGA-8870457 FarC-PTP4A2 binds RABGGTB IEA Gallus gallus A0A1D5PVS6 R-GGA-2424252 https://reactome.org/PathwayBrowser/#/R-GGA-2424252 COMP binds collagen, fibronectin, aggrecan and matrilins IEA Gallus gallus A0A1D5PVS9 R-GGA-8851110 https://reactome.org/PathwayBrowser/#/R-GGA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Gallus gallus A0A1D5PVS9 R-GGA-8851129 https://reactome.org/PathwayBrowser/#/R-GGA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Gallus gallus A0A1D5PVT8 R-GGA-197198 https://reactome.org/PathwayBrowser/#/R-GGA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Gallus gallus A0A1D5PVU3 R-GGA-8952618 https://reactome.org/PathwayBrowser/#/R-GGA-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PVU3 R-GGA-8952620 https://reactome.org/PathwayBrowser/#/R-GGA-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PVU3 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5PVU3 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5PVU3 R-GGA-8956200 https://reactome.org/PathwayBrowser/#/R-GGA-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PVU3 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PVU3 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PVU3 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PVU3 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PVU6 R-GGA-5577234 https://reactome.org/PathwayBrowser/#/R-GGA-5577234 KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region IEA Gallus gallus A0A1D5PVV4 R-GGA-6791222 https://reactome.org/PathwayBrowser/#/R-GGA-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Gallus gallus A0A1D5PVV4 R-GGA-6791227 https://reactome.org/PathwayBrowser/#/R-GGA-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Gallus gallus A0A1D5PVV7 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PVV7 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PVV7 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PVV7 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PVX9 R-GGA-5695964 https://reactome.org/PathwayBrowser/#/R-GGA-5695964 ABHD14B hydrolyses PNPB IEA Gallus gallus A0A1D5PW03 R-GGA-9018758 https://reactome.org/PathwayBrowser/#/R-GGA-9018758 RHOH binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PW04 R-GGA-5250930 https://reactome.org/PathwayBrowser/#/R-GGA-5250930 B-WICH recruits histone acetyltransferases IEA Gallus gallus A0A1D5PW04 R-GGA-5250938 https://reactome.org/PathwayBrowser/#/R-GGA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Gallus gallus A0A1D5PW04 R-GGA-5250947 https://reactome.org/PathwayBrowser/#/R-GGA-5250947 B-WICH complex binds rDNA promoter IEA Gallus gallus A0A1D5PW04 R-GGA-73757 https://reactome.org/PathwayBrowser/#/R-GGA-73757 Binding of RRN3 to RNA Polymerase I IEA Gallus gallus A0A1D5PW04 R-GGA-73758 https://reactome.org/PathwayBrowser/#/R-GGA-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Gallus gallus A0A1D5PW04 R-GGA-73769 https://reactome.org/PathwayBrowser/#/R-GGA-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Gallus gallus A0A1D5PW04 R-GGA-74986 https://reactome.org/PathwayBrowser/#/R-GGA-74986 Elongation of pre-rRNA transcript IEA Gallus gallus A0A1D5PW04 R-GGA-74993 https://reactome.org/PathwayBrowser/#/R-GGA-74993 PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box IEA Gallus gallus A0A1D5PW06 R-GGA-5362412 https://reactome.org/PathwayBrowser/#/R-GGA-5362412 SYVN1 ubiquitinates Hh C-terminal fragments IEA Gallus gallus A0A1D5PW06 R-GGA-5362441 https://reactome.org/PathwayBrowser/#/R-GGA-5362441 C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane IEA Gallus gallus A0A1D5PW06 R-GGA-5362459 https://reactome.org/PathwayBrowser/#/R-GGA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Gallus gallus A0A1D5PW06 R-GGA-8866542 https://reactome.org/PathwayBrowser/#/R-GGA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Gallus gallus A0A1D5PW06 R-GGA-8866546 https://reactome.org/PathwayBrowser/#/R-GGA-8866546 RNF5 and RNF185 ubiquitinate misfolded CFTR IEA Gallus gallus A0A1D5PW06 R-GGA-8866551 https://reactome.org/PathwayBrowser/#/R-GGA-8866551 CFTR binds components of the ERAD machinery for ubiquitination and degradation IEA Gallus gallus A0A1D5PW25 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus A0A1D5PW25 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus A0A1D5PW25 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus A0A1D5PW25 R-GGA-5694417 https://reactome.org/PathwayBrowser/#/R-GGA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Gallus gallus A0A1D5PW25 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus A0A1D5PW25 R-GGA-5694428 https://reactome.org/PathwayBrowser/#/R-GGA-5694428 LMAN family proteins bind glycosylated cargo IEA Gallus gallus A0A1D5PW25 R-GGA-5694446 https://reactome.org/PathwayBrowser/#/R-GGA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Gallus gallus A0A1D5PW25 R-GGA-5694522 https://reactome.org/PathwayBrowser/#/R-GGA-5694522 Inner coat assembly and cargo binding IEA Gallus gallus A0A1D5PW25 R-GGA-5694527 https://reactome.org/PathwayBrowser/#/R-GGA-5694527 Loss of SAR1B GTPase IEA Gallus gallus A0A1D5PW46 R-GGA-2162192 https://reactome.org/PathwayBrowser/#/R-GGA-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Gallus gallus A0A1D5PW46 R-GGA-8986181 https://reactome.org/PathwayBrowser/#/R-GGA-8986181 PITRM1 proteolyzes mitochondrial targeting peptides (presequences) IEA Gallus gallus A0A1D5PW49 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus A0A1D5PW49 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus A0A1D5PW49 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus A0A1D5PW49 R-GGA-1981120 https://reactome.org/PathwayBrowser/#/R-GGA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Gallus gallus A0A1D5PW49 R-GGA-2002460 https://reactome.org/PathwayBrowser/#/R-GGA-2002460 P4HB binds Collagen chains IEA Gallus gallus A0A1D5PW49 R-GGA-8948228 https://reactome.org/PathwayBrowser/#/R-GGA-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Gallus gallus A0A1D5PW49 R-GGA-8948231 https://reactome.org/PathwayBrowser/#/R-GGA-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Gallus gallus A0A1D5PW49 R-GGA-8948232 https://reactome.org/PathwayBrowser/#/R-GGA-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Gallus gallus A0A1D5PW49 R-GGA-8948234 https://reactome.org/PathwayBrowser/#/R-GGA-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Gallus gallus A0A1D5PW54 R-GGA-1299318 https://reactome.org/PathwayBrowser/#/R-GGA-1299318 Activation of TASK IEA Gallus gallus A0A1D5PW54 R-GGA-5578910 https://reactome.org/PathwayBrowser/#/R-GGA-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Gallus gallus A0A1D5PW58 R-GGA-6807877 https://reactome.org/PathwayBrowser/#/R-GGA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Gallus gallus A0A1D5PW58 R-GGA-6811417 https://reactome.org/PathwayBrowser/#/R-GGA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Gallus gallus A0A1D5PW58 R-GGA-6811418 https://reactome.org/PathwayBrowser/#/R-GGA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Gallus gallus A0A1D5PW58 R-GGA-9014449 https://reactome.org/PathwayBrowser/#/R-GGA-9014449 RHOG binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PW62 R-GGA-390593 https://reactome.org/PathwayBrowser/#/R-GGA-390593 ATP Hydrolysis By Myosin IEA Gallus gallus A0A1D5PW62 R-GGA-390595 https://reactome.org/PathwayBrowser/#/R-GGA-390595 Calcium Binds Troponin-C IEA Gallus gallus A0A1D5PW62 R-GGA-390597 https://reactome.org/PathwayBrowser/#/R-GGA-390597 Release Of ADP From Myosin IEA Gallus gallus A0A1D5PW62 R-GGA-390598 https://reactome.org/PathwayBrowser/#/R-GGA-390598 Myosin Binds ATP IEA Gallus gallus A0A1D5PW68 R-GGA-156808 https://reactome.org/PathwayBrowser/#/R-GGA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Gallus gallus A0A1D5PW68 R-GGA-157849 https://reactome.org/PathwayBrowser/#/R-GGA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Gallus gallus A0A1D5PW68 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus A0A1D5PW68 R-GGA-72676 https://reactome.org/PathwayBrowser/#/R-GGA-72676 eIF3 and eIF1A bind to the 40S subunit IEA Gallus gallus A0A1D5PW68 R-GGA-72691 https://reactome.org/PathwayBrowser/#/R-GGA-72691 Formation of the 43S pre-initiation complex IEA Gallus gallus A0A1D5PW68 R-GGA-72697 https://reactome.org/PathwayBrowser/#/R-GGA-72697 Start codon recognition IEA Gallus gallus A0A1D5PW83 R-GGA-5669013 https://reactome.org/PathwayBrowser/#/R-GGA-5669013 EDA-3 binds EDA2R IEA Gallus gallus A0A1D5PW86 R-GGA-964737 https://reactome.org/PathwayBrowser/#/R-GGA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus A0A1D5PW86 R-GGA-964825 https://reactome.org/PathwayBrowser/#/R-GGA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus A0A1D5PW86 R-GGA-964830 https://reactome.org/PathwayBrowser/#/R-GGA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus A0A1D5PW98 R-GGA-9934021 https://reactome.org/PathwayBrowser/#/R-GGA-9934021 Formation of neuronal progenitor BAF (npBAF) IEA Gallus gallus A0A1D5PW98 R-GGA-9934024 https://reactome.org/PathwayBrowser/#/R-GGA-9934024 SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10 IEA Gallus gallus A0A1D5PWA4 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PWD4 R-GGA-6799777 https://reactome.org/PathwayBrowser/#/R-GGA-6799777 TP53 family members bind PPP1R13B or TP53BP2 IEA Gallus gallus A0A1D5PWD8 R-GGA-5693153 https://reactome.org/PathwayBrowser/#/R-GGA-5693153 PPM1K dephosphorylates p-BCKDH IEA Gallus gallus A0A1D5PWD8 R-GGA-6792572 https://reactome.org/PathwayBrowser/#/R-GGA-6792572 LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST IEA Gallus gallus A0A1D5PWD8 R-GGA-9018758 https://reactome.org/PathwayBrowser/#/R-GGA-9018758 RHOH binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PWD8 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1D5PWD8 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1D5PWD8 R-GGA-9859148 https://reactome.org/PathwayBrowser/#/R-GGA-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Gallus gallus A0A1D5PWD8 R-GGA-9859163 https://reactome.org/PathwayBrowser/#/R-GGA-9859163 DBT transfers BCAA to CoA IEA Gallus gallus A0A1D5PWD8 R-GGA-9859172 https://reactome.org/PathwayBrowser/#/R-GGA-9859172 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus A0A1D5PWE0 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PWG7 R-GGA-5617815 https://reactome.org/PathwayBrowser/#/R-GGA-5617815 BBSome binds RAB3IP IEA Gallus gallus A0A1D5PWG7 R-GGA-5624126 https://reactome.org/PathwayBrowser/#/R-GGA-5624126 ARL6:GTP and the BBSome bind ciliary cargo IEA Gallus gallus A0A1D5PWG7 R-GGA-5624127 https://reactome.org/PathwayBrowser/#/R-GGA-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Gallus gallus A0A1D5PWG7 R-GGA-5624129 https://reactome.org/PathwayBrowser/#/R-GGA-5624129 LZTFL1 binds the BBSome and prevents its traffic to the cilium IEA Gallus gallus A0A1D5PWH2 R-GGA-1022129 https://reactome.org/PathwayBrowser/#/R-GGA-1022129 ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans IEA Gallus gallus A0A1D5PWH2 R-GGA-2046285 https://reactome.org/PathwayBrowser/#/R-GGA-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Gallus gallus A0A1D5PWH2 R-GGA-4084984 https://reactome.org/PathwayBrowser/#/R-GGA-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Gallus gallus A0A1D5PWH2 R-GGA-9605600 https://reactome.org/PathwayBrowser/#/R-GGA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Gallus gallus A0A1D5PWH2 R-GGA-981497 https://reactome.org/PathwayBrowser/#/R-GGA-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Gallus gallus A0A1D5PWK9 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus A0A1D5PWL4 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PWL4 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PWL4 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PWL4 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PWN4 R-GGA-5681987 https://reactome.org/PathwayBrowser/#/R-GGA-5681987 LC3 is cleaved by ATG4 IEA Gallus gallus A0A1D5PWN4 R-GGA-5682377 https://reactome.org/PathwayBrowser/#/R-GGA-5682377 LC3 de-lipidation by ATG4 IEA Gallus gallus A0A1D5PWT4 R-GGA-3322995 https://reactome.org/PathwayBrowser/#/R-GGA-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Gallus gallus A0A1D5PWT4 R-GGA-3323050 https://reactome.org/PathwayBrowser/#/R-GGA-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Gallus gallus A0A1D5PWT4 R-GGA-9035484 https://reactome.org/PathwayBrowser/#/R-GGA-9035484 MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST IEA Gallus gallus A0A1D5PWU2 R-GGA-9913330 https://reactome.org/PathwayBrowser/#/R-GGA-9913330 SGCG,SGCZ and SGCA, SGCE bind SGCB:SGCD IEA Gallus gallus A0A1D5PWU2 R-GGA-9913332 https://reactome.org/PathwayBrowser/#/R-GGA-9913332 DAG1(30-653), DAG1(654-895) and SSPN bind SGC IEA Gallus gallus A0A1D5PWU2 R-GGA-9913336 https://reactome.org/PathwayBrowser/#/R-GGA-9913336 SGC:DAG1:SSPN complex translocates to plasma membrane IEA Gallus gallus A0A1D5PWU2 R-GGA-9913338 https://reactome.org/PathwayBrowser/#/R-GGA-9913338 Sarcoglycan complex (SGC) translocates to the Golgi membrane IEA Gallus gallus A0A1D5PWU2 R-GGA-9913339 https://reactome.org/PathwayBrowser/#/R-GGA-9913339 Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC IEA Gallus gallus A0A1D5PWW3 R-GGA-194632 https://reactome.org/PathwayBrowser/#/R-GGA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Gallus gallus A0A1D5PWW3 R-GGA-194689 https://reactome.org/PathwayBrowser/#/R-GGA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Gallus gallus A0A1D5PWY3 R-GGA-8867240 https://reactome.org/PathwayBrowser/#/R-GGA-8867240 EPCAM binds itself to form homotypic cell adhesion IEA Gallus gallus A0A1D5PWZ2 R-GGA-71825 https://reactome.org/PathwayBrowser/#/R-GGA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Gallus gallus A0A1D5PWZ9 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PX13 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5PX13 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5PX13 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5PX13 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5PX13 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5PX20 R-GGA-9013435 https://reactome.org/PathwayBrowser/#/R-GGA-9013435 RHOD auto-activates IEA Gallus gallus A0A1D5PX20 R-GGA-9013437 https://reactome.org/PathwayBrowser/#/R-GGA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Gallus gallus A0A1D5PX20 R-GGA-9013438 https://reactome.org/PathwayBrowser/#/R-GGA-9013438 RHOD binds effectors at the endosome membrane IEA Gallus gallus A0A1D5PX20 R-GGA-9013452 https://reactome.org/PathwayBrowser/#/R-GGA-9013452 RHOD:GTP translocates to the endosome membrane IEA Gallus gallus A0A1D5PX20 R-GGA-9693198 https://reactome.org/PathwayBrowser/#/R-GGA-9693198 RHOD binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PX20 R-GGA-9693207 https://reactome.org/PathwayBrowser/#/R-GGA-9693207 RHOD translocates to the mitochondrial outer membrane IEA Gallus gallus A0A1D5PX20 R-GGA-9693214 https://reactome.org/PathwayBrowser/#/R-GGA-9693214 RHOD binds effectors at the mitochondrial outer membrane IEA Gallus gallus A0A1D5PX20 R-GGA-9693243 https://reactome.org/PathwayBrowser/#/R-GGA-9693243 RHOD translocates to the Golgi membrane IEA Gallus gallus A0A1D5PX20 R-GGA-9693250 https://reactome.org/PathwayBrowser/#/R-GGA-9693250 RHOD binds effectors at the Golgi membrane IEA Gallus gallus A0A1D5PX29 R-GGA-9913339 https://reactome.org/PathwayBrowser/#/R-GGA-9913339 Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC IEA Gallus gallus A0A1D5PX32 R-GGA-72103 https://reactome.org/PathwayBrowser/#/R-GGA-72103 Formation of pre-mRNPs IEA Gallus gallus A0A1D5PX32 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus A0A1D5PX32 R-GGA-75079 https://reactome.org/PathwayBrowser/#/R-GGA-75079 Formation of AT-AC C complex IEA Gallus gallus A0A1D5PX32 R-GGA-75081 https://reactome.org/PathwayBrowser/#/R-GGA-75081 Formation of AT-AC B Complex IEA Gallus gallus A0A1D5PX32 R-GGA-75082 https://reactome.org/PathwayBrowser/#/R-GGA-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Gallus gallus A0A1D5PX32 R-GGA-75083 https://reactome.org/PathwayBrowser/#/R-GGA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Gallus gallus A0A1D5PX32 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5PX49 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus A0A1D5PX49 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus A0A1D5PX49 R-GGA-8980691 https://reactome.org/PathwayBrowser/#/R-GGA-8980691 RHOA GEFs activate RHOA IEA Gallus gallus A0A1D5PX49 R-GGA-9696268 https://reactome.org/PathwayBrowser/#/R-GGA-9696268 RND3 binds effectors IEA Gallus gallus A0A1D5PX49 R-GGA-9696271 https://reactome.org/PathwayBrowser/#/R-GGA-9696271 RND1 binds effectors IEA Gallus gallus A0A1D5PX53 R-GGA-388824 https://reactome.org/PathwayBrowser/#/R-GGA-388824 PTPRF, PTPRS, PTPRD bind Liprins IEA Gallus gallus A0A1D5PX53 R-GGA-74733 https://reactome.org/PathwayBrowser/#/R-GGA-74733 Insulin receptor de-phosphorylation IEA Gallus gallus A0A1D5PX55 R-GGA-9854961 https://reactome.org/PathwayBrowser/#/R-GGA-9854961 SDHAF4 binds to FAD-SDHA IEA Gallus gallus A0A1D5PX65 R-GGA-109636 https://reactome.org/PathwayBrowser/#/R-GGA-109636 Recognition and Binding of Core Promoter Elements by TFIID IEA Gallus gallus A0A1D5PX65 R-GGA-109637 https://reactome.org/PathwayBrowser/#/R-GGA-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Gallus gallus A0A1D5PX65 R-GGA-109638 https://reactome.org/PathwayBrowser/#/R-GGA-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Gallus gallus A0A1D5PX65 R-GGA-109639 https://reactome.org/PathwayBrowser/#/R-GGA-109639 Formation of the closed pre-initiation complex IEA Gallus gallus A0A1D5PX65 R-GGA-73946 https://reactome.org/PathwayBrowser/#/R-GGA-73946 Abortive initiation after formation of the first phosphodiester bond IEA Gallus gallus A0A1D5PX65 R-GGA-75095 https://reactome.org/PathwayBrowser/#/R-GGA-75095 Binding of TFIIE to the growing preinitiation complex IEA Gallus gallus A0A1D5PX65 R-GGA-75850 https://reactome.org/PathwayBrowser/#/R-GGA-75850 Addition of the third nucleotide on the nascent transcript IEA Gallus gallus A0A1D5PX65 R-GGA-75856 https://reactome.org/PathwayBrowser/#/R-GGA-75856 Abortive Initiation Before Second Transition IEA Gallus gallus A0A1D5PX65 R-GGA-75861 https://reactome.org/PathwayBrowser/#/R-GGA-75861 NTP Binds Active Site of RNA Polymerase II IEA Gallus gallus A0A1D5PX65 R-GGA-75862 https://reactome.org/PathwayBrowser/#/R-GGA-75862 Fall Back to Closed Pre-initiation Complex IEA Gallus gallus A0A1D5PX65 R-GGA-75864 https://reactome.org/PathwayBrowser/#/R-GGA-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Gallus gallus A0A1D5PX65 R-GGA-75866 https://reactome.org/PathwayBrowser/#/R-GGA-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Gallus gallus A0A1D5PX65 R-GGA-75869 https://reactome.org/PathwayBrowser/#/R-GGA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Gallus gallus A0A1D5PX65 R-GGA-75873 https://reactome.org/PathwayBrowser/#/R-GGA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Gallus gallus A0A1D5PX65 R-GGA-75949 https://reactome.org/PathwayBrowser/#/R-GGA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Gallus gallus A0A1D5PX65 R-GGA-9613494 https://reactome.org/PathwayBrowser/#/R-GGA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Gallus gallus A0A1D5PX65 R-GGA-9613497 https://reactome.org/PathwayBrowser/#/R-GGA-9613497 Unwinding DNA for the nascent transcript IEA Gallus gallus A0A1D5PX66 R-GGA-1855222 https://reactome.org/PathwayBrowser/#/R-GGA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Gallus gallus A0A1D5PX68 R-GGA-372449 https://reactome.org/PathwayBrowser/#/R-GGA-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion IEA Gallus gallus A0A1D5PX68 R-GGA-75849 https://reactome.org/PathwayBrowser/#/R-GGA-75849 SLC25A1 exchanges CIT and MAL IEA Gallus gallus A0A1D5PX69 R-GGA-1655831 https://reactome.org/PathwayBrowser/#/R-GGA-1655831 SREBP1A,1C,2 translocates to the nucleus IEA Gallus gallus A0A1D5PX69 R-GGA-1655842 https://reactome.org/PathwayBrowser/#/R-GGA-1655842 S1P hydrolyzes SREBP1A,1C,2 IEA Gallus gallus A0A1D5PX69 R-GGA-1655851 https://reactome.org/PathwayBrowser/#/R-GGA-1655851 S2P hydrolyzes SREBP1A,1C,2 IEA Gallus gallus A0A1D5PX69 R-GGA-2065539 https://reactome.org/PathwayBrowser/#/R-GGA-2065539 SREBP1A,1C,2:Importin beta-1 dissociates IEA Gallus gallus A0A1D5PX69 R-GGA-2065549 https://reactome.org/PathwayBrowser/#/R-GGA-2065549 SREBP1A,1C,2 binds SREBP1A,1C,2 forming dimers IEA Gallus gallus A0A1D5PX69 R-GGA-2065550 https://reactome.org/PathwayBrowser/#/R-GGA-2065550 SREBP1A,1C,2 binds Importin beta-1 IEA Gallus gallus A0A1D5PX69 R-GGA-9755937 https://reactome.org/PathwayBrowser/#/R-GGA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Gallus gallus A0A1D5PX74 R-GGA-8952630 https://reactome.org/PathwayBrowser/#/R-GGA-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PX74 R-GGA-8952631 https://reactome.org/PathwayBrowser/#/R-GGA-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PX74 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5PX74 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5PX74 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PX74 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PX74 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PX74 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PX84 R-GGA-112381 https://reactome.org/PathwayBrowser/#/R-GGA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Gallus gallus A0A1D5PX84 R-GGA-112385 https://reactome.org/PathwayBrowser/#/R-GGA-112385 Addition of nucleotides leads to transcript elongation IEA Gallus gallus A0A1D5PX84 R-GGA-112392 https://reactome.org/PathwayBrowser/#/R-GGA-112392 Resumption of elongation after recovery from pausing IEA Gallus gallus A0A1D5PX84 R-GGA-112395 https://reactome.org/PathwayBrowser/#/R-GGA-112395 Abortive termination of elongation after arrest IEA Gallus gallus A0A1D5PX84 R-GGA-112396 https://reactome.org/PathwayBrowser/#/R-GGA-112396 Separation of elongating transcript from template IEA Gallus gallus A0A1D5PX84 R-GGA-113411 https://reactome.org/PathwayBrowser/#/R-GGA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Gallus gallus A0A1D5PX84 R-GGA-113412 https://reactome.org/PathwayBrowser/#/R-GGA-113412 Pol II elongation complex moves on the template as transcript elongates IEA Gallus gallus A0A1D5PX84 R-GGA-113413 https://reactome.org/PathwayBrowser/#/R-GGA-113413 TFIIS-mediated recovery of elongation from arrest IEA Gallus gallus A0A1D5PX84 R-GGA-113414 https://reactome.org/PathwayBrowser/#/R-GGA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Gallus gallus A0A1D5PX90 R-GGA-5672972 https://reactome.org/PathwayBrowser/#/R-GGA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Gallus gallus A0A1D5PX90 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus A0A1D5PX90 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus A0A1D5PX90 R-GGA-5672980 https://reactome.org/PathwayBrowser/#/R-GGA-5672980 Dissociation of RAS:RAF complex IEA Gallus gallus A0A1D5PX90 R-GGA-9657599 https://reactome.org/PathwayBrowser/#/R-GGA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Gallus gallus A0A1D5PX90 R-GGA-9657603 https://reactome.org/PathwayBrowser/#/R-GGA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Gallus gallus A0A1D5PX90 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus A0A1D5PX90 R-GGA-9657608 https://reactome.org/PathwayBrowser/#/R-GGA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Gallus gallus A0A1D5PX95 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus A0A1D5PX99 R-GGA-8857692 https://reactome.org/PathwayBrowser/#/R-GGA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Gallus gallus A0A1D5PXA1 R-GGA-8851797 https://reactome.org/PathwayBrowser/#/R-GGA-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Gallus gallus A0A1D5PXA1 R-GGA-8982641 https://reactome.org/PathwayBrowser/#/R-GGA-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Gallus gallus A0A1D5PXA1 R-GGA-8982645 https://reactome.org/PathwayBrowser/#/R-GGA-8982645 GRKs bind ADRB2:Catecholamine IEA Gallus gallus A0A1D5PXB4 R-GGA-1067640 https://reactome.org/PathwayBrowser/#/R-GGA-1067640 IL6 binds IL6R-2 IEA Gallus gallus A0A1D5PXB4 R-GGA-1067651 https://reactome.org/PathwayBrowser/#/R-GGA-1067651 IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) IEA Gallus gallus A0A1D5PXB4 R-GGA-1067659 https://reactome.org/PathwayBrowser/#/R-GGA-1067659 Assembly of hexameric IL-6 receptor IEA Gallus gallus A0A1D5PXB4 R-GGA-1067667 https://reactome.org/PathwayBrowser/#/R-GGA-1067667 IL6 binds IL6R IEA Gallus gallus A0A1D5PXB4 R-GGA-1067676 https://reactome.org/PathwayBrowser/#/R-GGA-1067676 IL6:IL6R-2 binds IL6ST-2 IEA Gallus gallus A0A1D5PXB4 R-GGA-1067688 https://reactome.org/PathwayBrowser/#/R-GGA-1067688 IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) IEA Gallus gallus A0A1D5PXB4 R-GGA-1112510 https://reactome.org/PathwayBrowser/#/R-GGA-1112510 IL6ST is tyrosine phosphorylated IEA Gallus gallus A0A1D5PXB4 R-GGA-1112514 https://reactome.org/PathwayBrowser/#/R-GGA-1112514 JAK activation IEA Gallus gallus A0A1D5PXB4 R-GGA-1112565 https://reactome.org/PathwayBrowser/#/R-GGA-1112565 Tyrosine phosphorylated IL6ST binds STAT1,STAT3 IEA Gallus gallus A0A1D5PXB4 R-GGA-1112602 https://reactome.org/PathwayBrowser/#/R-GGA-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Gallus gallus A0A1D5PXB4 R-GGA-1112604 https://reactome.org/PathwayBrowser/#/R-GGA-1112604 Phosphorylated STATs are released IEA Gallus gallus A0A1D5PXB4 R-GGA-1112690 https://reactome.org/PathwayBrowser/#/R-GGA-1112690 PTPN11 binds CBL IEA Gallus gallus A0A1D5PXB4 R-GGA-1112703 https://reactome.org/PathwayBrowser/#/R-GGA-1112703 PTPN11 is phosphorylated IEA Gallus gallus A0A1D5PXB4 R-GGA-1112708 https://reactome.org/PathwayBrowser/#/R-GGA-1112708 PTPN11 binds p-Y759-IL6ST IEA Gallus gallus A0A1D5PXB4 R-GGA-1112727 https://reactome.org/PathwayBrowser/#/R-GGA-1112727 Serine phosphorylation of STATs IEA Gallus gallus A0A1D5PXB4 R-GGA-1112755 https://reactome.org/PathwayBrowser/#/R-GGA-1112755 SOCS3 binds IL6ST IEA Gallus gallus A0A1D5PXB4 R-GGA-9681294 https://reactome.org/PathwayBrowser/#/R-GGA-9681294 IL6R binds IL6R inhibitors IEA Gallus gallus A0A1D5PXB8 R-GGA-446372 https://reactome.org/PathwayBrowser/#/R-GGA-446372 Association of PARVA with TESK1 IEA Gallus gallus A0A1D5PXC6 R-GGA-168053 https://reactome.org/PathwayBrowser/#/R-GGA-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Gallus gallus A0A1D5PXC6 R-GGA-168136 https://reactome.org/PathwayBrowser/#/R-GGA-168136 Activated JNKs phosphorylate c-JUN IEA Gallus gallus A0A1D5PXC6 R-GGA-168162 https://reactome.org/PathwayBrowser/#/R-GGA-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Gallus gallus A0A1D5PXC6 R-GGA-450348 https://reactome.org/PathwayBrowser/#/R-GGA-450348 Activated human JNKs migrate to nucleoplasm IEA Gallus gallus A0A1D5PXC7 R-GGA-373342 https://reactome.org/PathwayBrowser/#/R-GGA-373342 CX3CR1 binds CX3CL1 IEA Gallus gallus A0A1D5PXC7 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5PXC7 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5PXC7 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5PXD8 R-GGA-2106614 https://reactome.org/PathwayBrowser/#/R-GGA-2106614 Duplex miRNA is loaded into Argonaute IEA Gallus gallus A0A1D5PXD8 R-GGA-2106615 https://reactome.org/PathwayBrowser/#/R-GGA-2106615 Removal of siRNA passenger strand IEA Gallus gallus A0A1D5PXD8 R-GGA-2106625 https://reactome.org/PathwayBrowser/#/R-GGA-2106625 Duplex siRNA is loaded into Argonaute IEA Gallus gallus A0A1D5PXD8 R-GGA-210805 https://reactome.org/PathwayBrowser/#/R-GGA-210805 Removal of miRNA passenger strand IEA Gallus gallus A0A1D5PXD8 R-GGA-426464 https://reactome.org/PathwayBrowser/#/R-GGA-426464 Dicer cleaves double-stranded RNA to yield double-stranded siRNA IEA Gallus gallus A0A1D5PXD8 R-GGA-426489 https://reactome.org/PathwayBrowser/#/R-GGA-426489 RISC binds inexactly matching target RNAs IEA Gallus gallus A0A1D5PXD8 R-GGA-426522 https://reactome.org/PathwayBrowser/#/R-GGA-426522 Nonendonucleolytic RISC binds exactly matching target RNAs IEA Gallus gallus A0A1D5PXD8 R-GGA-5578742 https://reactome.org/PathwayBrowser/#/R-GGA-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Gallus gallus A0A1D5PXE3 R-GGA-350058 https://reactome.org/PathwayBrowser/#/R-GGA-350058 Formation of CSL NCOR corepressor complex IEA Gallus gallus A0A1D5PXE3 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus A0A1D5PXE3 R-GGA-4616015 https://reactome.org/PathwayBrowser/#/R-GGA-4616015 SUMOylation of HDAC2 with SUMO1 IEA Gallus gallus A0A1D5PXE3 R-GGA-73739 https://reactome.org/PathwayBrowser/#/R-GGA-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter IEA Gallus gallus A0A1D5PXE3 R-GGA-8943780 https://reactome.org/PathwayBrowser/#/R-GGA-8943780 SALL4 recruits NuRD to PTEN gene IEA Gallus gallus A0A1D5PXE3 R-GGA-9679787 https://reactome.org/PathwayBrowser/#/R-GGA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Gallus gallus A0A1D5PXE3 R-GGA-9701565 https://reactome.org/PathwayBrowser/#/R-GGA-9701565 HDACs deacetylate p-STAT3 dimers IEA Gallus gallus A0A1D5PXE3 R-GGA-996727 https://reactome.org/PathwayBrowser/#/R-GGA-996727 REST recruits the BHC complex IEA Gallus gallus A0A1D5PXE5 R-GGA-3928578 https://reactome.org/PathwayBrowser/#/R-GGA-3928578 EPH receptors autophosphorylate IEA Gallus gallus A0A1D5PXE5 R-GGA-3928591 https://reactome.org/PathwayBrowser/#/R-GGA-3928591 EPH:EFN tetramers oligomerise IEA Gallus gallus A0A1D5PXE5 R-GGA-3928597 https://reactome.org/PathwayBrowser/#/R-GGA-3928597 EPH:EFN dimers tetramerise IEA Gallus gallus A0A1D5PXE5 R-GGA-3928604 https://reactome.org/PathwayBrowser/#/R-GGA-3928604 SFKs phosphorylate VAV2,3 IEA Gallus gallus A0A1D5PXE5 R-GGA-3928607 https://reactome.org/PathwayBrowser/#/R-GGA-3928607 p-EPHs bind VAV2,3 IEA Gallus gallus A0A1D5PXE5 R-GGA-3928628 https://reactome.org/PathwayBrowser/#/R-GGA-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5PXE5 R-GGA-3928642 https://reactome.org/PathwayBrowser/#/R-GGA-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus A0A1D5PXE5 R-GGA-3928646 https://reactome.org/PathwayBrowser/#/R-GGA-3928646 EPHAs bind EFNAs IEA Gallus gallus A0A1D5PXE5 R-GGA-3928651 https://reactome.org/PathwayBrowser/#/R-GGA-3928651 NGEF exchanges GTP for GDP on RHOA IEA Gallus gallus A0A1D5PXE5 R-GGA-4093327 https://reactome.org/PathwayBrowser/#/R-GGA-4093327 EPHA binds TIAM1 IEA Gallus gallus A0A1D5PXE5 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PXE5 R-GGA-9014294 https://reactome.org/PathwayBrowser/#/R-GGA-9014294 RAC2 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PXE5 R-GGA-9014449 https://reactome.org/PathwayBrowser/#/R-GGA-9014449 RHOG binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PXE5 R-GGA-9018766 https://reactome.org/PathwayBrowser/#/R-GGA-9018766 RHOU binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PXE5 R-GGA-9018794 https://reactome.org/PathwayBrowser/#/R-GGA-9018794 RHOV binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PXE5 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PXE5 R-GGA-9696266 https://reactome.org/PathwayBrowser/#/R-GGA-9696266 RND2 binds effectors IEA Gallus gallus A0A1D5PXE5 R-GGA-9696268 https://reactome.org/PathwayBrowser/#/R-GGA-9696268 RND3 binds effectors IEA Gallus gallus A0A1D5PXE5 R-GGA-9696271 https://reactome.org/PathwayBrowser/#/R-GGA-9696271 RND1 binds effectors IEA Gallus gallus A0A1D5PXG9 R-GGA-350058 https://reactome.org/PathwayBrowser/#/R-GGA-350058 Formation of CSL NCOR corepressor complex IEA Gallus gallus A0A1D5PXG9 R-GGA-3777129 https://reactome.org/PathwayBrowser/#/R-GGA-3777129 HDAC3 containing complexes deacetylate histone IEA Gallus gallus A0A1D5PXG9 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus A0A1D5PXG9 R-GGA-400183 https://reactome.org/PathwayBrowser/#/R-GGA-400183 PPARA:RXRA binds Corepressors of PPARA IEA Gallus gallus A0A1D5PXG9 R-GGA-9734475 https://reactome.org/PathwayBrowser/#/R-GGA-9734475 PPARA binds fibrates IEA Gallus gallus A0A1D5PXG9 R-GGA-9843115 https://reactome.org/PathwayBrowser/#/R-GGA-9843115 Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci IEA Gallus gallus A0A1D5PXG9 R-GGA-9843117 https://reactome.org/PathwayBrowser/#/R-GGA-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1D5PXG9 R-GGA-9843118 https://reactome.org/PathwayBrowser/#/R-GGA-9843118 RXRA binds ligands IEA Gallus gallus A0A1D5PXH1 R-GGA-72103 https://reactome.org/PathwayBrowser/#/R-GGA-72103 Formation of pre-mRNPs IEA Gallus gallus A0A1D5PXH1 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5PXI1 R-GGA-6784402 https://reactome.org/PathwayBrowser/#/R-GGA-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Gallus gallus A0A1D5PXI1 R-GGA-70679 https://reactome.org/PathwayBrowser/#/R-GGA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Gallus gallus A0A1D5PXI1 R-GGA-9929439 https://reactome.org/PathwayBrowser/#/R-GGA-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Gallus gallus A0A1D5PXK3 R-GGA-8943987 https://reactome.org/PathwayBrowser/#/R-GGA-8943987 SCUBE1, SCUBE3 oligomerize IEA Gallus gallus A0A1D5PXK6 R-GGA-5693061 https://reactome.org/PathwayBrowser/#/R-GGA-5693061 STAMBP binds STAM IEA Gallus gallus A0A1D5PXK6 R-GGA-5696547 https://reactome.org/PathwayBrowser/#/R-GGA-5696547 STAMBPL1 is a deubiquitinase IEA Gallus gallus A0A1D5PXL0 R-GGA-1605624 https://reactome.org/PathwayBrowser/#/R-GGA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Gallus gallus A0A1D5PXL0 R-GGA-1606312 https://reactome.org/PathwayBrowser/#/R-GGA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Gallus gallus A0A1D5PXL0 R-GGA-1630306 https://reactome.org/PathwayBrowser/#/R-GGA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Gallus gallus A0A1D5PXL0 R-GGA-2090079 https://reactome.org/PathwayBrowser/#/R-GGA-2090079 GLB1 hydrolyses linker chain(2) IEA Gallus gallus A0A1D5PXL0 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5PXL0 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PXL0 R-GGA-9638120 https://reactome.org/PathwayBrowser/#/R-GGA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Gallus gallus A0A1D5PXM6 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus A0A1D5PXM6 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1D5PXM6 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1D5PXM6 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1D5PXM6 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus A0A1D5PXN5 R-GGA-5263614 https://reactome.org/PathwayBrowser/#/R-GGA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Gallus gallus A0A1D5PXN5 R-GGA-5263616 https://reactome.org/PathwayBrowser/#/R-GGA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Gallus gallus A0A1D5PXN5 R-GGA-73646 https://reactome.org/PathwayBrowser/#/R-GGA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Gallus gallus A0A1D5PXP0 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PXP0 R-GGA-6805546 https://reactome.org/PathwayBrowser/#/R-GGA-6805546 Keratin type I binds keratin type II IEA Gallus gallus A0A1D5PXP0 R-GGA-6805573 https://reactome.org/PathwayBrowser/#/R-GGA-6805573 Keratin type I/type II heterodimers form tetramers IEA Gallus gallus A0A1D5PXP0 R-GGA-6806610 https://reactome.org/PathwayBrowser/#/R-GGA-6806610 Keratin filament formation IEA Gallus gallus A0A1D5PXP0 R-GGA-6806613 https://reactome.org/PathwayBrowser/#/R-GGA-6806613 Keratin tetramers bind to form unit length filaments IEA Gallus gallus A0A1D5PXP0 R-GGA-6806629 https://reactome.org/PathwayBrowser/#/R-GGA-6806629 Formation of tonofilament bundles IEA Gallus gallus A0A1D5PXP0 R-GGA-6809393 https://reactome.org/PathwayBrowser/#/R-GGA-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Gallus gallus A0A1D5PXP0 R-GGA-6810357 https://reactome.org/PathwayBrowser/#/R-GGA-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Gallus gallus A0A1D5PXQ1 R-GGA-111439 https://reactome.org/PathwayBrowser/#/R-GGA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Gallus gallus A0A1D5PXQ1 R-GGA-158441 https://reactome.org/PathwayBrowser/#/R-GGA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PXQ1 R-GGA-158447 https://reactome.org/PathwayBrowser/#/R-GGA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Gallus gallus A0A1D5PXQ1 R-GGA-158481 https://reactome.org/PathwayBrowser/#/R-GGA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PXQ1 R-GGA-158484 https://reactome.org/PathwayBrowser/#/R-GGA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Gallus gallus A0A1D5PXQ1 R-GGA-159046 https://reactome.org/PathwayBrowser/#/R-GGA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Gallus gallus A0A1D5PXQ1 R-GGA-159050 https://reactome.org/PathwayBrowser/#/R-GGA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Gallus gallus A0A1D5PXQ1 R-GGA-170825 https://reactome.org/PathwayBrowser/#/R-GGA-170825 NPC exports GCK1 from nucleus IEA Gallus gallus A0A1D5PXQ1 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1D5PXQ1 R-GGA-2990880 https://reactome.org/PathwayBrowser/#/R-GGA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Gallus gallus A0A1D5PXQ1 R-GGA-2990882 https://reactome.org/PathwayBrowser/#/R-GGA-2990882 CDK1 phosphorylates NUP98 IEA Gallus gallus A0A1D5PXQ1 R-GGA-4551649 https://reactome.org/PathwayBrowser/#/R-GGA-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Gallus gallus A0A1D5PXQ1 R-GGA-4551679 https://reactome.org/PathwayBrowser/#/R-GGA-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Gallus gallus A0A1D5PXQ1 R-GGA-4615872 https://reactome.org/PathwayBrowser/#/R-GGA-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Gallus gallus A0A1D5PXQ1 R-GGA-4615987 https://reactome.org/PathwayBrowser/#/R-GGA-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Gallus gallus A0A1D5PXQ1 R-GGA-4655355 https://reactome.org/PathwayBrowser/#/R-GGA-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Gallus gallus A0A1D5PXQ1 R-GGA-5228523 https://reactome.org/PathwayBrowser/#/R-GGA-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Gallus gallus A0A1D5PXQ1 R-GGA-5578744 https://reactome.org/PathwayBrowser/#/R-GGA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Gallus gallus A0A1D5PXQ1 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1D5PXQ1 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1D5PXQ1 R-GGA-77587 https://reactome.org/PathwayBrowser/#/R-GGA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Gallus gallus A0A1D5PXQ6 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5PXR5 R-GGA-1236943 https://reactome.org/PathwayBrowser/#/R-GGA-1236943 Loading of antigen peptide onto MHC class I molecule IEA Gallus gallus A0A1D5PXR5 R-GGA-1236954 https://reactome.org/PathwayBrowser/#/R-GGA-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Gallus gallus A0A1D5PXR5 R-GGA-1236964 https://reactome.org/PathwayBrowser/#/R-GGA-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Gallus gallus A0A1D5PXR5 R-GGA-1236965 https://reactome.org/PathwayBrowser/#/R-GGA-1236965 Export of peptide loaded MHC class I complex to PM IEA Gallus gallus A0A1D5PXR5 R-GGA-198955 https://reactome.org/PathwayBrowser/#/R-GGA-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Gallus gallus A0A1D5PXR5 R-GGA-199062 https://reactome.org/PathwayBrowser/#/R-GGA-199062 KLRC1:KLRD1 heterodimer interacts with HLA-E IEA Gallus gallus A0A1D5PXR5 R-GGA-210289 https://reactome.org/PathwayBrowser/#/R-GGA-210289 Recruitment of SYK to p-DAP12 IEA Gallus gallus A0A1D5PXR5 R-GGA-2395412 https://reactome.org/PathwayBrowser/#/R-GGA-2395412 Phosphorylation of SYK IEA Gallus gallus A0A1D5PXR5 R-GGA-2396594 https://reactome.org/PathwayBrowser/#/R-GGA-2396594 Phosphorylation of SLP-76 by p-SYK IEA Gallus gallus A0A1D5PXR5 R-GGA-2424480 https://reactome.org/PathwayBrowser/#/R-GGA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PXR5 R-GGA-2424482 https://reactome.org/PathwayBrowser/#/R-GGA-2424482 p85 regulatory unit of PI3K binds p-6Y-SYK IEA Gallus gallus A0A1D5PXR5 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus A0A1D5PXR5 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus A0A1D5PXR5 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus A0A1D5PXR5 R-GGA-5691154 https://reactome.org/PathwayBrowser/#/R-GGA-5691154 HFE binds TFRC dimer IEA Gallus gallus A0A1D5PXR5 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5PXR5 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PXR5 R-GGA-8863973 https://reactome.org/PathwayBrowser/#/R-GGA-8863973 Fusion of ERC and phagosome IEA Gallus gallus A0A1D5PXR5 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus A0A1D5PXR5 R-GGA-8951499 https://reactome.org/PathwayBrowser/#/R-GGA-8951499 Loading of antigenic peptides on to class I MHC IEA Gallus gallus A0A1D5PXR5 R-GGA-983138 https://reactome.org/PathwayBrowser/#/R-GGA-983138 Transport of MHC heterotrimer to ER exit site IEA Gallus gallus A0A1D5PXR5 R-GGA-983145 https://reactome.org/PathwayBrowser/#/R-GGA-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Gallus gallus A0A1D5PXR5 R-GGA-983146 https://reactome.org/PathwayBrowser/#/R-GGA-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Gallus gallus A0A1D5PXR5 R-GGA-983421 https://reactome.org/PathwayBrowser/#/R-GGA-983421 Journey of cargo through Golgi complex IEA Gallus gallus A0A1D5PXR5 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus A0A1D5PXR5 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus A0A1D5PXR5 R-GGA-983425 https://reactome.org/PathwayBrowser/#/R-GGA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Gallus gallus A0A1D5PXR5 R-GGA-983427 https://reactome.org/PathwayBrowser/#/R-GGA-983427 Expression of peptide bound class I MHC on cell surface IEA Gallus gallus A0A1D5PXS3 R-GGA-975340 https://reactome.org/PathwayBrowser/#/R-GGA-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Gallus gallus A0A1D5PXS9 R-GGA-177923 https://reactome.org/PathwayBrowser/#/R-GGA-177923 Sustained activation of SRC kinase by SHP2 IEA Gallus gallus A0A1D5PXS9 R-GGA-202233 https://reactome.org/PathwayBrowser/#/R-GGA-202233 Inactivation of Lck by Csk IEA Gallus gallus A0A1D5PXS9 R-GGA-203774 https://reactome.org/PathwayBrowser/#/R-GGA-203774 Interaction of Csk with PAG IEA Gallus gallus A0A1D5PXS9 R-GGA-354077 https://reactome.org/PathwayBrowser/#/R-GGA-354077 Integrin alphaIIb beta3 activation IEA Gallus gallus A0A1D5PXS9 R-GGA-354149 https://reactome.org/PathwayBrowser/#/R-GGA-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Gallus gallus A0A1D5PXS9 R-GGA-377641 https://reactome.org/PathwayBrowser/#/R-GGA-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Gallus gallus A0A1D5PXS9 R-GGA-377644 https://reactome.org/PathwayBrowser/#/R-GGA-377644 Release of CSK from SRC IEA Gallus gallus A0A1D5PXS9 R-GGA-389758 https://reactome.org/PathwayBrowser/#/R-GGA-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Gallus gallus A0A1D5PXS9 R-GGA-389759 https://reactome.org/PathwayBrowser/#/R-GGA-389759 Interaction of SHP-1 or SHP-2 with phospho PD-1 IEA Gallus gallus A0A1D5PXS9 R-GGA-389762 https://reactome.org/PathwayBrowser/#/R-GGA-389762 Phosphorylation of PD-1 IEA Gallus gallus A0A1D5PXS9 R-GGA-432096 https://reactome.org/PathwayBrowser/#/R-GGA-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Gallus gallus A0A1D5PXS9 R-GGA-443905 https://reactome.org/PathwayBrowser/#/R-GGA-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Gallus gallus A0A1D5PXS9 R-GGA-443910 https://reactome.org/PathwayBrowser/#/R-GGA-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Gallus gallus A0A1D5PXS9 R-GGA-5672972 https://reactome.org/PathwayBrowser/#/R-GGA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Gallus gallus A0A1D5PXS9 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus A0A1D5PXS9 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus A0A1D5PXS9 R-GGA-5672980 https://reactome.org/PathwayBrowser/#/R-GGA-5672980 Dissociation of RAS:RAF complex IEA Gallus gallus A0A1D5PXS9 R-GGA-8855375 https://reactome.org/PathwayBrowser/#/R-GGA-8855375 PTPN22 dissociates from CSK IEA Gallus gallus A0A1D5PXS9 R-GGA-9018758 https://reactome.org/PathwayBrowser/#/R-GGA-9018758 RHOH binds effectors at the plasma membrane IEA Gallus gallus A0A1D5PXS9 R-GGA-9657599 https://reactome.org/PathwayBrowser/#/R-GGA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Gallus gallus A0A1D5PXS9 R-GGA-9657603 https://reactome.org/PathwayBrowser/#/R-GGA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Gallus gallus A0A1D5PXS9 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus A0A1D5PXS9 R-GGA-9657608 https://reactome.org/PathwayBrowser/#/R-GGA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Gallus gallus A0A1D5PXT0 R-GGA-4332236 https://reactome.org/PathwayBrowser/#/R-GGA-4332236 CBL neddylates TGFBR2 IEA Gallus gallus A0A1D5PXT0 R-GGA-8951661 https://reactome.org/PathwayBrowser/#/R-GGA-8951661 Transfer of NEDD8 to AcM-UBE2M IEA Gallus gallus A0A1D5PXT0 R-GGA-8951751 https://reactome.org/PathwayBrowser/#/R-GGA-8951751 Doubly neddylated UBA3:NAE1 binds AcM-UBE2M IEA Gallus gallus A0A1D5PXT0 R-GGA-8952618 https://reactome.org/PathwayBrowser/#/R-GGA-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PXT0 R-GGA-8952620 https://reactome.org/PathwayBrowser/#/R-GGA-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PXT0 R-GGA-8952626 https://reactome.org/PathwayBrowser/#/R-GGA-8952626 AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PXT0 R-GGA-8952630 https://reactome.org/PathwayBrowser/#/R-GGA-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PXT0 R-GGA-8952631 https://reactome.org/PathwayBrowser/#/R-GGA-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PXT0 R-GGA-8952638 https://reactome.org/PathwayBrowser/#/R-GGA-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PXT0 R-GGA-8952639 https://reactome.org/PathwayBrowser/#/R-GGA-8952639 NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PXT0 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PXT0 R-GGA-983152 https://reactome.org/PathwayBrowser/#/R-GGA-983152 Transfer of ubiquitin from E1 to E2 IEA Gallus gallus A0A1D5PXT0 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PXT0 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PXT4 R-GGA-5692749 https://reactome.org/PathwayBrowser/#/R-GGA-5692749 CDC14A,B bind MAPK6 IEA Gallus gallus A0A1D5PXT4 R-GGA-5692754 https://reactome.org/PathwayBrowser/#/R-GGA-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Gallus gallus A0A1D5PXT4 R-GGA-5692764 https://reactome.org/PathwayBrowser/#/R-GGA-5692764 MAPK6 binds CCND3 IEA Gallus gallus A0A1D5PXU7 R-GGA-418436 https://reactome.org/PathwayBrowser/#/R-GGA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Gallus gallus A0A1D5PXU7 R-GGA-5617178 https://reactome.org/PathwayBrowser/#/R-GGA-5617178 ATP2B4 binds to NOS1, inhibiting it IEA Gallus gallus A0A1D5PXW5 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1D5PXZ9 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1D5PXZ9 R-GGA-8853734 https://reactome.org/PathwayBrowser/#/R-GGA-8853734 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 IEA Gallus gallus A0A1D5PXZ9 R-GGA-8853737 https://reactome.org/PathwayBrowser/#/R-GGA-8853737 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 IEA Gallus gallus A0A1D5PXZ9 R-GGA-8853753 https://reactome.org/PathwayBrowser/#/R-GGA-8853753 2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 IEA Gallus gallus A0A1D5PXZ9 R-GGA-8853755 https://reactome.org/PathwayBrowser/#/R-GGA-8853755 2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 IEA Gallus gallus A0A1D5PXZ9 R-GGA-8853762 https://reactome.org/PathwayBrowser/#/R-GGA-8853762 RET dimerizes IEA Gallus gallus A0A1D5PXZ9 R-GGA-8853774 https://reactome.org/PathwayBrowser/#/R-GGA-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Gallus gallus A0A1D5PXZ9 R-GGA-8853792 https://reactome.org/PathwayBrowser/#/R-GGA-8853792 RET tyrosine phosphorylation IEA Gallus gallus A0A1D5PXZ9 R-GGA-8853793 https://reactome.org/PathwayBrowser/#/R-GGA-8853793 p-5Y-RET complexes bind GRB2 IEA Gallus gallus A0A1D5PXZ9 R-GGA-8853800 https://reactome.org/PathwayBrowser/#/R-GGA-8853800 ARTN binds RET:GFRA1,GFRA3 IEA Gallus gallus A0A1D5PXZ9 R-GGA-8854897 https://reactome.org/PathwayBrowser/#/R-GGA-8854897 p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2 IEA Gallus gallus A0A1D5PXZ9 R-GGA-8854899 https://reactome.org/PathwayBrowser/#/R-GGA-8854899 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 IEA Gallus gallus A0A1D5PXZ9 R-GGA-8854905 https://reactome.org/PathwayBrowser/#/R-GGA-8854905 p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K IEA Gallus gallus A0A1D5PXZ9 R-GGA-8854981 https://reactome.org/PathwayBrowser/#/R-GGA-8854981 SHC1 in the RET complex is phosphorylated IEA Gallus gallus A0A1D5PXZ9 R-GGA-8855508 https://reactome.org/PathwayBrowser/#/R-GGA-8855508 p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 IEA Gallus gallus A0A1D5PXZ9 R-GGA-8855564 https://reactome.org/PathwayBrowser/#/R-GGA-8855564 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 IEA Gallus gallus A0A1D5PXZ9 R-GGA-8855617 https://reactome.org/PathwayBrowser/#/R-GGA-8855617 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 IEA Gallus gallus A0A1D5PXZ9 R-GGA-8855747 https://reactome.org/PathwayBrowser/#/R-GGA-8855747 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP IEA Gallus gallus A0A1D5PXZ9 R-GGA-8855915 https://reactome.org/PathwayBrowser/#/R-GGA-8855915 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors IEA Gallus gallus A0A1D5PY09 R-GGA-3371435 https://reactome.org/PathwayBrowser/#/R-GGA-3371435 Constitutive phosphorylation by GSK3 IEA Gallus gallus A0A1D5PY09 R-GGA-3371467 https://reactome.org/PathwayBrowser/#/R-GGA-3371467 SIRT1 deacetylates HSF1 IEA Gallus gallus A0A1D5PY09 R-GGA-3371518 https://reactome.org/PathwayBrowser/#/R-GGA-3371518 SIRT1 binds to HSF1 IEA Gallus gallus A0A1D5PY09 R-GGA-3371527 https://reactome.org/PathwayBrowser/#/R-GGA-3371527 HSF1 trimer translocates to the nucleus IEA Gallus gallus A0A1D5PY09 R-GGA-3371531 https://reactome.org/PathwayBrowser/#/R-GGA-3371531 Constitutive phosphorylation by pERK1/2 IEA Gallus gallus A0A1D5PY09 R-GGA-3371554 https://reactome.org/PathwayBrowser/#/R-GGA-3371554 HSF1 acetylation at Lys80 IEA Gallus gallus A0A1D5PY09 R-GGA-3371582 https://reactome.org/PathwayBrowser/#/R-GGA-3371582 HSBP1 binds HSF1 trimer IEA Gallus gallus A0A1D5PY09 R-GGA-3371586 https://reactome.org/PathwayBrowser/#/R-GGA-3371586 Dissociation of cytosolic HSF1:HSP90 complex IEA Gallus gallus A0A1D5PY09 R-GGA-3371591 https://reactome.org/PathwayBrowser/#/R-GGA-3371591 Trimerization of cytosolic HSF1 IEA Gallus gallus A0A1D5PY09 R-GGA-4793911 https://reactome.org/PathwayBrowser/#/R-GGA-4793911 MAPKAPK2 phosphorylates HSF1 IEA Gallus gallus A0A1D5PY09 R-GGA-4793925 https://reactome.org/PathwayBrowser/#/R-GGA-4793925 p-S303,307-HSF1 binds YWHAE (14-3-3) IEA Gallus gallus A0A1D5PY09 R-GGA-5082356 https://reactome.org/PathwayBrowser/#/R-GGA-5082356 HSF1-mediated gene expression IEA Gallus gallus A0A1D5PY09 R-GGA-5082384 https://reactome.org/PathwayBrowser/#/R-GGA-5082384 HSP70:DNAJB1 binds HSF1 IEA Gallus gallus A0A1D5PY09 R-GGA-5082387 https://reactome.org/PathwayBrowser/#/R-GGA-5082387 Phosphorylation of HSF1 at Ser230 induces transactivation IEA Gallus gallus A0A1D5PY09 R-GGA-5082391 https://reactome.org/PathwayBrowser/#/R-GGA-5082391 Trimerization of HSF1 in the nucleus IEA Gallus gallus A0A1D5PY09 R-GGA-5082405 https://reactome.org/PathwayBrowser/#/R-GGA-5082405 Phosphorylation of HSF1 at Ser326 induces transactivation IEA Gallus gallus A0A1D5PY09 R-GGA-5082409 https://reactome.org/PathwayBrowser/#/R-GGA-5082409 Dissociation of HSF1:HSP90 complex in the nucleus IEA Gallus gallus A0A1D5PY09 R-GGA-5324617 https://reactome.org/PathwayBrowser/#/R-GGA-5324617 HSP90:FKBP4:PTGES3 binds HSF1 trimer IEA Gallus gallus A0A1D5PY09 R-GGA-5333051 https://reactome.org/PathwayBrowser/#/R-GGA-5333051 RPA1 binds HSF1 IEA Gallus gallus A0A1D5PY09 R-GGA-9857091 https://reactome.org/PathwayBrowser/#/R-GGA-9857091 HSF1 is activated by phosphorylation, translocation to the nucleus, and trimerization IEA Gallus gallus A0A1D5PY26 R-GGA-8982012 https://reactome.org/PathwayBrowser/#/R-GGA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Gallus gallus A0A1D5PY26 R-GGA-8982019 https://reactome.org/PathwayBrowser/#/R-GGA-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Gallus gallus A0A1D5PY26 R-GGA-8982020 https://reactome.org/PathwayBrowser/#/R-GGA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Gallus gallus A0A1D5PY31 R-GGA-170158 https://reactome.org/PathwayBrowser/#/R-GGA-170158 CDC25A dephosphorylates CCNA:CDK1 IEA Gallus gallus A0A1D5PY31 R-GGA-170159 https://reactome.org/PathwayBrowser/#/R-GGA-170159 Translocation of Cdc25 to the nucleus IEA Gallus gallus A0A1D5PY31 R-GGA-174110 https://reactome.org/PathwayBrowser/#/R-GGA-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Gallus gallus A0A1D5PY31 R-GGA-69199 https://reactome.org/PathwayBrowser/#/R-GGA-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Gallus gallus A0A1D5PY31 R-GGA-69600 https://reactome.org/PathwayBrowser/#/R-GGA-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Gallus gallus A0A1D5PY31 R-GGA-69608 https://reactome.org/PathwayBrowser/#/R-GGA-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Gallus gallus A0A1D5PY32 R-GGA-444126 https://reactome.org/PathwayBrowser/#/R-GGA-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Gallus gallus A0A1D5PY38 R-GGA-8952630 https://reactome.org/PathwayBrowser/#/R-GGA-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PY38 R-GGA-8952631 https://reactome.org/PathwayBrowser/#/R-GGA-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Gallus gallus A0A1D5PY38 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1D5PY38 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1D5PY38 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PY38 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PY38 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PY38 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PY39 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1D5PY45 R-GGA-3465545 https://reactome.org/PathwayBrowser/#/R-GGA-3465545 PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 IEA Gallus gallus A0A1D5PY45 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus A0A1D5PY45 R-GGA-73739 https://reactome.org/PathwayBrowser/#/R-GGA-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter IEA Gallus gallus A0A1D5PY45 R-GGA-8943780 https://reactome.org/PathwayBrowser/#/R-GGA-8943780 SALL4 recruits NuRD to PTEN gene IEA Gallus gallus A0A1D5PY45 R-GGA-9679787 https://reactome.org/PathwayBrowser/#/R-GGA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Gallus gallus A0A1D5PY49 R-GGA-212222 https://reactome.org/PathwayBrowser/#/R-GGA-212222 PRC2 recruits DNA methyltransferases IEA Gallus gallus A0A1D5PY49 R-GGA-212252 https://reactome.org/PathwayBrowser/#/R-GGA-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Gallus gallus A0A1D5PY49 R-GGA-212263 https://reactome.org/PathwayBrowser/#/R-GGA-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Gallus gallus A0A1D5PY49 R-GGA-212269 https://reactome.org/PathwayBrowser/#/R-GGA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Gallus gallus A0A1D5PY49 R-GGA-2172678 https://reactome.org/PathwayBrowser/#/R-GGA-2172678 PHF8 demethylates histone H4K20me1 IEA Gallus gallus A0A1D5PY49 R-GGA-2288097 https://reactome.org/PathwayBrowser/#/R-GGA-2288097 Condensin II complex binds H4K20me1-containing nucleosomes IEA Gallus gallus A0A1D5PY49 R-GGA-2294580 https://reactome.org/PathwayBrowser/#/R-GGA-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Gallus gallus A0A1D5PY49 R-GGA-2294590 https://reactome.org/PathwayBrowser/#/R-GGA-2294590 PLK1 binds phosphorylated condensin II complex IEA Gallus gallus A0A1D5PY49 R-GGA-2301205 https://reactome.org/PathwayBrowser/#/R-GGA-2301205 SETD8 monomethylates histone H4 IEA Gallus gallus A0A1D5PY49 R-GGA-3229089 https://reactome.org/PathwayBrowser/#/R-GGA-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Gallus gallus A0A1D5PY49 R-GGA-3229102 https://reactome.org/PathwayBrowser/#/R-GGA-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Gallus gallus A0A1D5PY49 R-GGA-3240295 https://reactome.org/PathwayBrowser/#/R-GGA-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Gallus gallus A0A1D5PY49 R-GGA-3318415 https://reactome.org/PathwayBrowser/#/R-GGA-3318415 ATF2 acetylates histone H2B, H4 IEA Gallus gallus A0A1D5PY49 R-GGA-3364026 https://reactome.org/PathwayBrowser/#/R-GGA-3364026 SET1 complex trimethylates H3K4 at the MYC gene IEA Gallus gallus A0A1D5PY49 R-GGA-3662335 https://reactome.org/PathwayBrowser/#/R-GGA-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Gallus gallus A0A1D5PY49 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus A0A1D5PY49 R-GGA-3777129 https://reactome.org/PathwayBrowser/#/R-GGA-3777129 HDAC3 containing complexes deacetylate histone IEA Gallus gallus A0A1D5PY49 R-GGA-3782637 https://reactome.org/PathwayBrowser/#/R-GGA-3782637 HDAC8 deacetylates histones IEA Gallus gallus A0A1D5PY49 R-GGA-3782655 https://reactome.org/PathwayBrowser/#/R-GGA-3782655 HDAC10 deacetylates histone IEA Gallus gallus A0A1D5PY49 R-GGA-5250938 https://reactome.org/PathwayBrowser/#/R-GGA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Gallus gallus A0A1D5PY49 R-GGA-5578742 https://reactome.org/PathwayBrowser/#/R-GGA-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Gallus gallus A0A1D5PY49 R-GGA-5625784 https://reactome.org/PathwayBrowser/#/R-GGA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Gallus gallus A0A1D5PY49 R-GGA-5625796 https://reactome.org/PathwayBrowser/#/R-GGA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Gallus gallus A0A1D5PY49 R-GGA-5625797 https://reactome.org/PathwayBrowser/#/R-GGA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Gallus gallus A0A1D5PY49 R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus A0A1D5PY49 R-GGA-5625849 https://reactome.org/PathwayBrowser/#/R-GGA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Gallus gallus A0A1D5PY49 R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus A0A1D5PY49 R-GGA-5682586 https://reactome.org/PathwayBrowser/#/R-GGA-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Gallus gallus A0A1D5PY49 R-GGA-5682588 https://reactome.org/PathwayBrowser/#/R-GGA-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Gallus gallus A0A1D5PY49 R-GGA-5682598 https://reactome.org/PathwayBrowser/#/R-GGA-5682598 ATM phosphorylates HERC2 IEA Gallus gallus A0A1D5PY49 R-GGA-5682607 https://reactome.org/PathwayBrowser/#/R-GGA-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Gallus gallus A0A1D5PY49 R-GGA-5682629 https://reactome.org/PathwayBrowser/#/R-GGA-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Gallus gallus A0A1D5PY49 R-GGA-5682858 https://reactome.org/PathwayBrowser/#/R-GGA-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Gallus gallus A0A1D5PY49 R-GGA-5682863 https://reactome.org/PathwayBrowser/#/R-GGA-5682863 RNF168 binds DNA DSBs IEA Gallus gallus A0A1D5PY49 R-GGA-5682965 https://reactome.org/PathwayBrowser/#/R-GGA-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Gallus gallus A0A1D5PY49 R-GGA-5682967 https://reactome.org/PathwayBrowser/#/R-GGA-5682967 WHSC1 binds DNA DSBs IEA Gallus gallus A0A1D5PY49 R-GGA-5682983 https://reactome.org/PathwayBrowser/#/R-GGA-5682983 ATM phosphorylates WHSC1 IEA Gallus gallus A0A1D5PY49 R-GGA-5682992 https://reactome.org/PathwayBrowser/#/R-GGA-5682992 KDM4A,B bind H4K20Me2 IEA Gallus gallus A0A1D5PY49 R-GGA-5683077 https://reactome.org/PathwayBrowser/#/R-GGA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Gallus gallus A0A1D5PY49 R-GGA-5683384 https://reactome.org/PathwayBrowser/#/R-GGA-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Gallus gallus A0A1D5PY49 R-GGA-5683385 https://reactome.org/PathwayBrowser/#/R-GGA-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Gallus gallus A0A1D5PY49 R-GGA-5683425 https://reactome.org/PathwayBrowser/#/R-GGA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Gallus gallus A0A1D5PY49 R-GGA-5683735 https://reactome.org/PathwayBrowser/#/R-GGA-5683735 CHEK2 is recruited to DNA DSBs IEA Gallus gallus A0A1D5PY49 R-GGA-5683801 https://reactome.org/PathwayBrowser/#/R-GGA-5683801 CHEK2 phosphorylates BRCA1 IEA Gallus gallus A0A1D5PY49 R-GGA-5683930 https://reactome.org/PathwayBrowser/#/R-GGA-5683930 WICH phosphorylates H2AFX on Y142 IEA Gallus gallus A0A1D5PY49 R-GGA-5683964 https://reactome.org/PathwayBrowser/#/R-GGA-5683964 ATM phosphorylates EYA1-4 IEA Gallus gallus A0A1D5PY49 R-GGA-5683967 https://reactome.org/PathwayBrowser/#/R-GGA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Gallus gallus A0A1D5PY49 R-GGA-5683986 https://reactome.org/PathwayBrowser/#/R-GGA-5683986 APBB1 and MAPK8 bind diphosphorylated H2AFX IEA Gallus gallus A0A1D5PY49 R-GGA-5684052 https://reactome.org/PathwayBrowser/#/R-GGA-5684052 PIAS4 SUMOylates MDC1 IEA Gallus gallus A0A1D5PY49 R-GGA-5686685 https://reactome.org/PathwayBrowser/#/R-GGA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Gallus gallus A0A1D5PY49 R-GGA-5686704 https://reactome.org/PathwayBrowser/#/R-GGA-5686704 Activated ATM phosphorylates DCLRE1C IEA Gallus gallus A0A1D5PY49 R-GGA-5686900 https://reactome.org/PathwayBrowser/#/R-GGA-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Gallus gallus A0A1D5PY49 R-GGA-5693536 https://reactome.org/PathwayBrowser/#/R-GGA-5693536 ATM phosphorylates MDC1 IEA Gallus gallus A0A1D5PY49 R-GGA-5693549 https://reactome.org/PathwayBrowser/#/R-GGA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Gallus gallus A0A1D5PY49 R-GGA-5693551 https://reactome.org/PathwayBrowser/#/R-GGA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Gallus gallus A0A1D5PY49 R-GGA-5693566 https://reactome.org/PathwayBrowser/#/R-GGA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Gallus gallus A0A1D5PY49 R-GGA-5693602 https://reactome.org/PathwayBrowser/#/R-GGA-5693602 ATM recognizes H2AFX-Nucleosomes IEA Gallus gallus A0A1D5PY49 R-GGA-5696960 https://reactome.org/PathwayBrowser/#/R-GGA-5696960 USP49 deubiquitinates H2B IEA Gallus gallus A0A1D5PY49 R-GGA-606287 https://reactome.org/PathwayBrowser/#/R-GGA-606287 RSF complex binds the centromere IEA Gallus gallus A0A1D5PY49 R-GGA-606289 https://reactome.org/PathwayBrowser/#/R-GGA-606289 New CENPA-containing nucleosomes are deposited at the centromere IEA Gallus gallus A0A1D5PY49 R-GGA-69891 https://reactome.org/PathwayBrowser/#/R-GGA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Gallus gallus A0A1D5PY49 R-GGA-73718 https://reactome.org/PathwayBrowser/#/R-GGA-73718 UBF-1 Binds rDNA Promoter IEA Gallus gallus A0A1D5PY49 R-GGA-74986 https://reactome.org/PathwayBrowser/#/R-GGA-74986 Elongation of pre-rRNA transcript IEA Gallus gallus A0A1D5PY49 R-GGA-8936481 https://reactome.org/PathwayBrowser/#/R-GGA-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Gallus gallus A0A1D5PY49 R-GGA-8936584 https://reactome.org/PathwayBrowser/#/R-GGA-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Gallus gallus A0A1D5PY49 R-GGA-8936608 https://reactome.org/PathwayBrowser/#/R-GGA-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Gallus gallus A0A1D5PY49 R-GGA-8936621 https://reactome.org/PathwayBrowser/#/R-GGA-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Gallus gallus A0A1D5PY49 R-GGA-8937016 https://reactome.org/PathwayBrowser/#/R-GGA-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Gallus gallus A0A1D5PY49 R-GGA-8937022 https://reactome.org/PathwayBrowser/#/R-GGA-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Gallus gallus A0A1D5PY49 R-GGA-8937050 https://reactome.org/PathwayBrowser/#/R-GGA-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Gallus gallus A0A1D5PY49 R-GGA-8937113 https://reactome.org/PathwayBrowser/#/R-GGA-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Gallus gallus A0A1D5PY49 R-GGA-9009065 https://reactome.org/PathwayBrowser/#/R-GGA-9009065 FOXA1 and GATA3 bind to CCND1 promoter IEA Gallus gallus A0A1D5PY49 R-GGA-9009371 https://reactome.org/PathwayBrowser/#/R-GGA-9009371 Binding of AP1 transcriptional activator complexes to CCND1 promoter IEA Gallus gallus A0A1D5PY49 R-GGA-9011949 https://reactome.org/PathwayBrowser/#/R-GGA-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Gallus gallus A0A1D5PY49 R-GGA-9011952 https://reactome.org/PathwayBrowser/#/R-GGA-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Gallus gallus A0A1D5PY49 R-GGA-9011981 https://reactome.org/PathwayBrowser/#/R-GGA-9011981 EP300 is recruited to MYC and BCL2 genes IEA Gallus gallus A0A1D5PY49 R-GGA-9011983 https://reactome.org/PathwayBrowser/#/R-GGA-9011983 Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes IEA Gallus gallus A0A1D5PY49 R-GGA-9011984 https://reactome.org/PathwayBrowser/#/R-GGA-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Gallus gallus A0A1D5PY49 R-GGA-9011985 https://reactome.org/PathwayBrowser/#/R-GGA-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Gallus gallus A0A1D5PY49 R-GGA-9012000 https://reactome.org/PathwayBrowser/#/R-GGA-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Gallus gallus A0A1D5PY49 R-GGA-9749197 https://reactome.org/PathwayBrowser/#/R-GGA-9749197 ORC1 binds to H4K20me2 IEA Gallus gallus A0A1D5PY49 R-GGA-9842833 https://reactome.org/PathwayBrowser/#/R-GGA-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Gallus gallus A0A1D5PY49 R-GGA-9842835 https://reactome.org/PathwayBrowser/#/R-GGA-9842835 KRAB-ZFP binds retroelement DNA in chromatin IEA Gallus gallus A0A1D5PY49 R-GGA-9842839 https://reactome.org/PathwayBrowser/#/R-GGA-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1D5PY49 R-GGA-9843115 https://reactome.org/PathwayBrowser/#/R-GGA-9843115 Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci IEA Gallus gallus A0A1D5PY49 R-GGA-9843117 https://reactome.org/PathwayBrowser/#/R-GGA-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1D5PY49 R-GGA-9843118 https://reactome.org/PathwayBrowser/#/R-GGA-9843118 RXRA binds ligands IEA Gallus gallus A0A1D5PY49 R-GGA-9843120 https://reactome.org/PathwayBrowser/#/R-GGA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1D5PY49 R-GGA-9843978 https://reactome.org/PathwayBrowser/#/R-GGA-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1D5PY49 R-GGA-9844006 https://reactome.org/PathwayBrowser/#/R-GGA-9844006 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) IEA Gallus gallus A0A1D5PY49 R-GGA-9844015 https://reactome.org/PathwayBrowser/#/R-GGA-9844015 MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin IEA Gallus gallus A0A1D5PY49 R-GGA-9844057 https://reactome.org/PathwayBrowser/#/R-GGA-9844057 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome IEA Gallus gallus A0A1D5PY51 R-GGA-199131 https://reactome.org/PathwayBrowser/#/R-GGA-199131 PVR binds CD226 IEA Gallus gallus A0A1D5PY51 R-GGA-419003 https://reactome.org/PathwayBrowser/#/R-GGA-419003 Interaction of Nectins with Afadin IEA Gallus gallus A0A1D5PY51 R-GGA-419011 https://reactome.org/PathwayBrowser/#/R-GGA-419011 Transhomodimerization of Nectins IEA Gallus gallus A0A1D5PY51 R-GGA-420580 https://reactome.org/PathwayBrowser/#/R-GGA-420580 Nectin-1:PVRL3 trans heterodimer formation IEA Gallus gallus A0A1D5PY51 R-GGA-420582 https://reactome.org/PathwayBrowser/#/R-GGA-420582 Necl-1:Nectin-1 trans heterodimer interaction IEA Gallus gallus A0A1D5PY51 R-GGA-420593 https://reactome.org/PathwayBrowser/#/R-GGA-420593 PVR:PVRL3 trans heterodimer interaction IEA Gallus gallus A0A1D5PY51 R-GGA-420598 https://reactome.org/PathwayBrowser/#/R-GGA-420598 Nectin-1:Nectin-4 trans heterodimer formation IEA Gallus gallus A0A1D5PY51 R-GGA-433711 https://reactome.org/PathwayBrowser/#/R-GGA-433711 Cis-homodimerization of nectins IEA Gallus gallus A0A1D5PY52 R-GGA-1296043 https://reactome.org/PathwayBrowser/#/R-GGA-1296043 Activation of HCN channels IEA Gallus gallus A0A1D5PY52 R-GGA-1297444 https://reactome.org/PathwayBrowser/#/R-GGA-1297444 Binding of cAMP to HCN channels IEA Gallus gallus A0A1D5PY52 R-GGA-9726875 https://reactome.org/PathwayBrowser/#/R-GGA-9726875 HCNs:cAMP bind SNIs IEA Gallus gallus A0A1D5PY98 R-GGA-983152 https://reactome.org/PathwayBrowser/#/R-GGA-983152 Transfer of ubiquitin from E1 to E2 IEA Gallus gallus A0A1D5PY98 R-GGA-983153 https://reactome.org/PathwayBrowser/#/R-GGA-983153 E1 mediated ubiquitin activation IEA Gallus gallus A0A1D5PYB5 R-GGA-211923 https://reactome.org/PathwayBrowser/#/R-GGA-211923 CYP26C1 4-hydroxylates 9cRA IEA Gallus gallus A0A1D5PYB5 R-GGA-212007 https://reactome.org/PathwayBrowser/#/R-GGA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Gallus gallus A0A1D5PYB5 R-GGA-5362525 https://reactome.org/PathwayBrowser/#/R-GGA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Gallus gallus A0A1D5PYB7 R-GGA-1234159 https://reactome.org/PathwayBrowser/#/R-GGA-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Gallus gallus A0A1D5PYB7 R-GGA-1234163 https://reactome.org/PathwayBrowser/#/R-GGA-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Gallus gallus A0A1D5PYB7 R-GGA-1234173 https://reactome.org/PathwayBrowser/#/R-GGA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Gallus gallus A0A1D5PYB7 R-GGA-1234177 https://reactome.org/PathwayBrowser/#/R-GGA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Gallus gallus A0A1D5PYB7 R-GGA-1234183 https://reactome.org/PathwayBrowser/#/R-GGA-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Gallus gallus A0A1D5PYC2 R-GGA-1676162 https://reactome.org/PathwayBrowser/#/R-GGA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Gallus gallus A0A1D5PYC2 R-GGA-1676164 https://reactome.org/PathwayBrowser/#/R-GGA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Gallus gallus A0A1D5PYC2 R-GGA-1855180 https://reactome.org/PathwayBrowser/#/R-GGA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Gallus gallus A0A1D5PYC2 R-GGA-1855202 https://reactome.org/PathwayBrowser/#/R-GGA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Gallus gallus A0A1D5PYD2 R-GGA-3134946 https://reactome.org/PathwayBrowser/#/R-GGA-3134946 DDX41 ubiquitination by TRIM21 IEA Gallus gallus A0A1D5PYD2 R-GGA-9759154 https://reactome.org/PathwayBrowser/#/R-GGA-9759154 TRIM21 ubiquitinates SQSTM1 IEA Gallus gallus A0A1D5PYD2 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PYD2 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PYD2 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PYD2 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PYD8 R-GGA-2574840 https://reactome.org/PathwayBrowser/#/R-GGA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Gallus gallus A0A1D5PYD8 R-GGA-2574845 https://reactome.org/PathwayBrowser/#/R-GGA-2574845 AJUBA binds centrosome-associated AURKA IEA Gallus gallus A0A1D5PYD8 R-GGA-3000310 https://reactome.org/PathwayBrowser/#/R-GGA-3000310 AURKA phosphorylates PLK1 IEA Gallus gallus A0A1D5PYD8 R-GGA-3000319 https://reactome.org/PathwayBrowser/#/R-GGA-3000319 BORA binds PLK1 and AURKA IEA Gallus gallus A0A1D5PYD8 R-GGA-380272 https://reactome.org/PathwayBrowser/#/R-GGA-380272 Plk1-mediated phosphorylation of Nlp IEA Gallus gallus A0A1D5PYD8 R-GGA-380283 https://reactome.org/PathwayBrowser/#/R-GGA-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Gallus gallus A0A1D5PYD8 R-GGA-380294 https://reactome.org/PathwayBrowser/#/R-GGA-380294 Loss of C-Nap-1 from centrosomes IEA Gallus gallus A0A1D5PYD8 R-GGA-380311 https://reactome.org/PathwayBrowser/#/R-GGA-380311 Recruitment of Plk1 to centrosomes IEA Gallus gallus A0A1D5PYD8 R-GGA-380455 https://reactome.org/PathwayBrowser/#/R-GGA-380455 Recruitment of CDK11p58 to the centrosomes IEA Gallus gallus A0A1D5PYD8 R-GGA-380508 https://reactome.org/PathwayBrowser/#/R-GGA-380508 Translocation of NuMA to the centrosomes IEA Gallus gallus A0A1D5PYD8 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1D5PYD8 R-GGA-5626228 https://reactome.org/PathwayBrowser/#/R-GGA-5626228 The distal appendage proteins recruit TTBK2 IEA Gallus gallus A0A1D5PYD8 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1D5PYD8 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1D5PYD8 R-GGA-8853405 https://reactome.org/PathwayBrowser/#/R-GGA-8853405 TPX2 binds AURKA at centrosomes IEA Gallus gallus A0A1D5PYD8 R-GGA-8853419 https://reactome.org/PathwayBrowser/#/R-GGA-8853419 TPX2 promotes AURKA autophosphorylation IEA Gallus gallus A0A1D5PYE9 R-GGA-8871366 https://reactome.org/PathwayBrowser/#/R-GGA-8871366 p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP IEA Gallus gallus A0A1D5PYE9 R-GGA-8871370 https://reactome.org/PathwayBrowser/#/R-GGA-8871370 p-Y389,400-RUFY1 translocates from cytosol to early endosome membrane IEA Gallus gallus A0A1D5PYE9 R-GGA-8871373 https://reactome.org/PathwayBrowser/#/R-GGA-8871373 BMX phosphorylates RUFY1 IEA Gallus gallus A0A1D5PYE9 R-GGA-8871376 https://reactome.org/PathwayBrowser/#/R-GGA-8871376 p-Y389,400-RUFY1 binds PI3P IEA Gallus gallus A0A1D5PYF0 R-GGA-6786421 https://reactome.org/PathwayBrowser/#/R-GGA-6786421 CHIA hydrolyses chitin IEA Gallus gallus A0A1D5PYF4 R-GGA-196761 https://reactome.org/PathwayBrowser/#/R-GGA-196761 2xTPK1:Mg2+ phosphorylates THMN IEA Gallus gallus A0A1D5PYG9 R-GGA-8937989 https://reactome.org/PathwayBrowser/#/R-GGA-8937989 RUNX1 binds PRC1 complexes IEA Gallus gallus A0A1D5PYG9 R-GGA-8954082 https://reactome.org/PathwayBrowser/#/R-GGA-8954082 E2F6 binds the PRC1 complex IEA Gallus gallus A0A1D5PYH2 R-GGA-437300 https://reactome.org/PathwayBrowser/#/R-GGA-437300 SLC31A1 transports Cu2+ from extracellular region to cytosol IEA Gallus gallus A0A1D5PYI7 R-GGA-429860 https://reactome.org/PathwayBrowser/#/R-GGA-429860 DCP1-DCP2 complex decaps mRNA IEA Gallus gallus A0A1D5PYI7 R-GGA-429978 https://reactome.org/PathwayBrowser/#/R-GGA-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Gallus gallus A0A1D5PYJ6 R-GGA-6797630 https://reactome.org/PathwayBrowser/#/R-GGA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Gallus gallus A0A1D5PYM3 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PYM3 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PYP2 R-GGA-8877813 https://reactome.org/PathwayBrowser/#/R-GGA-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Gallus gallus A0A1D5PYP4 R-GGA-8874705 https://reactome.org/PathwayBrowser/#/R-GGA-8874705 TTPA transports alpha-TOH from lysosomal membrane to plasma membrane IEA Gallus gallus A0A1D5PYP4 R-GGA-8874718 https://reactome.org/PathwayBrowser/#/R-GGA-8874718 TTPA binds alpha-TOH IEA Gallus gallus A0A1D5PYQ3 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1D5PYQ3 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1D5PYQ3 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1D5PYQ6 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1D5PYQ6 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1D5PYQ6 R-GGA-2466068 https://reactome.org/PathwayBrowser/#/R-GGA-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Gallus gallus A0A1D5PYQ6 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1D5PYQ6 R-GGA-2468039 https://reactome.org/PathwayBrowser/#/R-GGA-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Gallus gallus A0A1D5PYQ6 R-GGA-2468040 https://reactome.org/PathwayBrowser/#/R-GGA-2468040 Cohesin binds PDS5 and WAPAL IEA Gallus gallus A0A1D5PYQ6 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1D5PYQ6 R-GGA-2468293 https://reactome.org/PathwayBrowser/#/R-GGA-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Gallus gallus A0A1D5PYQ6 R-GGA-2470935 https://reactome.org/PathwayBrowser/#/R-GGA-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Gallus gallus A0A1D5PYQ6 R-GGA-2473152 https://reactome.org/PathwayBrowser/#/R-GGA-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Gallus gallus A0A1D5PYQ6 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1D5PYQ6 R-GGA-2545203 https://reactome.org/PathwayBrowser/#/R-GGA-2545203 Deacetylation of cleaved cohesin IEA Gallus gallus A0A1D5PYQ6 R-GGA-2545253 https://reactome.org/PathwayBrowser/#/R-GGA-2545253 Deacetylation of cohesin IEA Gallus gallus A0A1D5PYQ9 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus A0A1D5PYQ9 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus A0A1D5PYQ9 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus A0A1D5PYQ9 R-GGA-1981120 https://reactome.org/PathwayBrowser/#/R-GGA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Gallus gallus A0A1D5PYQ9 R-GGA-2002460 https://reactome.org/PathwayBrowser/#/R-GGA-2002460 P4HB binds Collagen chains IEA Gallus gallus A0A1D5PYQ9 R-GGA-2089971 https://reactome.org/PathwayBrowser/#/R-GGA-2089971 Secretion of collagens IEA Gallus gallus A0A1D5PYQ9 R-GGA-8944227 https://reactome.org/PathwayBrowser/#/R-GGA-8944227 Association of procollagen type XXII IEA Gallus gallus A0A1D5PYQ9 R-GGA-8944246 https://reactome.org/PathwayBrowser/#/R-GGA-8944246 Association of procollagen type XXI IEA Gallus gallus A0A1D5PYQ9 R-GGA-8948228 https://reactome.org/PathwayBrowser/#/R-GGA-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Gallus gallus A0A1D5PYQ9 R-GGA-8948231 https://reactome.org/PathwayBrowser/#/R-GGA-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Gallus gallus A0A1D5PYQ9 R-GGA-8948232 https://reactome.org/PathwayBrowser/#/R-GGA-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Gallus gallus A0A1D5PYQ9 R-GGA-8948234 https://reactome.org/PathwayBrowser/#/R-GGA-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Gallus gallus A0A1D5PYR9 R-GGA-202704 https://reactome.org/PathwayBrowser/#/R-GGA-202704 Integrin alphaXbeta2 binds JAM3 IEA Gallus gallus A0A1D5PYR9 R-GGA-202727 https://reactome.org/PathwayBrowser/#/R-GGA-202727 Integrin alphaMbeta2 (MAC1) binds JAM3 IEA Gallus gallus A0A1D5PYR9 R-GGA-216069 https://reactome.org/PathwayBrowser/#/R-GGA-216069 Interaction of integrin alphaDbeta2 with fibrin IEA Gallus gallus A0A1D5PYR9 R-GGA-216082 https://reactome.org/PathwayBrowser/#/R-GGA-216082 Interaction of integrin alphaXbeta2 with fibrin IEA Gallus gallus A0A1D5PYR9 R-GGA-2559439 https://reactome.org/PathwayBrowser/#/R-GGA-2559439 CD14:LPS binds CR3 IEA Gallus gallus A0A1D5PYR9 R-GGA-2681667 https://reactome.org/PathwayBrowser/#/R-GGA-2681667 TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 IEA Gallus gallus A0A1D5PYR9 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PYR9 R-GGA-6798747 https://reactome.org/PathwayBrowser/#/R-GGA-6798747 Exocytosis of tertiary granule membrane proteins IEA Gallus gallus A0A1D5PYR9 R-GGA-6799350 https://reactome.org/PathwayBrowser/#/R-GGA-6799350 Exocytosis of specific granule membrane proteins IEA Gallus gallus A0A1D5PYR9 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1D5PYT1 R-GGA-376419 https://reactome.org/PathwayBrowser/#/R-GGA-376419 Formation of NR-MED1 Coactivator Complex IEA Gallus gallus A0A1D5PYT1 R-GGA-382096 https://reactome.org/PathwayBrowser/#/R-GGA-382096 Formation of NR-NCOR Corepressor Complex IEA Gallus gallus A0A1D5PYT1 R-GGA-4341016 https://reactome.org/PathwayBrowser/#/R-GGA-4341016 PIAS1 SUMOylates NR3C2 (Mineralcorticoid Receptor) with SUMO1 IEA Gallus gallus A0A1D5PYT1 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus A0A1D5PYT1 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus A0A1D5PYT1 R-GGA-5618099 https://reactome.org/PathwayBrowser/#/R-GGA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Gallus gallus A0A1D5PYT1 R-GGA-9725855 https://reactome.org/PathwayBrowser/#/R-GGA-9725855 NR3C2 binds NR3C2 antagonists IEA Gallus gallus A0A1D5PYT1 R-GGA-9726509 https://reactome.org/PathwayBrowser/#/R-GGA-9726509 NR3C2 binds fludrocortisone IEA Gallus gallus A0A1D5PYT7 R-GGA-481007 https://reactome.org/PathwayBrowser/#/R-GGA-481007 Exocytosis of platelet alpha granule contents IEA Gallus gallus A0A1D5PYT9 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PYT9 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PYT9 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PYT9 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PYU0 R-GGA-5205649 https://reactome.org/PathwayBrowser/#/R-GGA-5205649 p62 links damaged mitochondria to LC3 IEA Gallus gallus A0A1D5PYU0 R-GGA-5205663 https://reactome.org/PathwayBrowser/#/R-GGA-5205663 LC3 binds the autophagosome membrane Atg5-Atg12 complex IEA Gallus gallus A0A1D5PYU0 R-GGA-5205673 https://reactome.org/PathwayBrowser/#/R-GGA-5205673 p62 binds ubiquitinated mitochondrial substrates IEA Gallus gallus A0A1D5PYU0 R-GGA-9018824 https://reactome.org/PathwayBrowser/#/R-GGA-9018824 RHOT2 binds effectors at the mitochondrial outer membrane IEA Gallus gallus A0A1D5PYU0 R-GGA-9824888 https://reactome.org/PathwayBrowser/#/R-GGA-9824888 OPTN, TBK1 bind ubiquitinated MOM proteins IEA Gallus gallus A0A1D5PYU0 R-GGA-9824892 https://reactome.org/PathwayBrowser/#/R-GGA-9824892 MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria IEA Gallus gallus A0A1D5PYU0 R-GGA-9824894 https://reactome.org/PathwayBrowser/#/R-GGA-9824894 TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins IEA Gallus gallus A0A1D5PYU0 R-GGA-9824897 https://reactome.org/PathwayBrowser/#/R-GGA-9824897 p-S-TBK1 phosphorylates OPTN IEA Gallus gallus A0A1D5PYU0 R-GGA-9835009 https://reactome.org/PathwayBrowser/#/R-GGA-9835009 PRKN binds p-S-Ub:MOM proteins IEA Gallus gallus A0A1D5PYU0 R-GGA-9840807 https://reactome.org/PathwayBrowser/#/R-GGA-9840807 OPTN binds ATG9A IEA Gallus gallus A0A1D5PYU0 R-GGA-992703 https://reactome.org/PathwayBrowser/#/R-GGA-992703 Mitofusins trans-interact linking mitochondria prior to fusion IEA Gallus gallus A0A1D5PYU1 R-GGA-114670 https://reactome.org/PathwayBrowser/#/R-GGA-114670 GPIb-IX-V binds to vWF:Collagen complex IEA Gallus gallus A0A1D5PYU1 R-GGA-114671 https://reactome.org/PathwayBrowser/#/R-GGA-114671 vWF binds to collagen IEA Gallus gallus A0A1D5PYU1 R-GGA-1454757 https://reactome.org/PathwayBrowser/#/R-GGA-1454757 Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 IEA Gallus gallus A0A1D5PYU1 R-GGA-1454822 https://reactome.org/PathwayBrowser/#/R-GGA-1454822 Collagen type I degradation by MMP1,2,8,13, PRSS2 IEA Gallus gallus A0A1D5PYU1 R-GGA-1474266 https://reactome.org/PathwayBrowser/#/R-GGA-1474266 Formation of collagen fibrils IEA Gallus gallus A0A1D5PYU1 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus A0A1D5PYU1 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus A0A1D5PYU1 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus A0A1D5PYU1 R-GGA-1981120 https://reactome.org/PathwayBrowser/#/R-GGA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Gallus gallus A0A1D5PYU1 R-GGA-2002428 https://reactome.org/PathwayBrowser/#/R-GGA-2002428 Removal of fibrillar collagen N-propeptides IEA Gallus gallus A0A1D5PYU1 R-GGA-2002460 https://reactome.org/PathwayBrowser/#/R-GGA-2002460 P4HB binds Collagen chains IEA Gallus gallus A0A1D5PYU1 R-GGA-2002466 https://reactome.org/PathwayBrowser/#/R-GGA-2002466 Formation of allysine by LOX IEA Gallus gallus A0A1D5PYU1 R-GGA-2089971 https://reactome.org/PathwayBrowser/#/R-GGA-2089971 Secretion of collagens IEA Gallus gallus A0A1D5PYU1 R-GGA-216045 https://reactome.org/PathwayBrowser/#/R-GGA-216045 Collagen type I binds integrin alpha11beta1 IEA Gallus gallus A0A1D5PYU1 R-GGA-2213201 https://reactome.org/PathwayBrowser/#/R-GGA-2213201 Formation of collagen fibres IEA Gallus gallus A0A1D5PYU1 R-GGA-2213205 https://reactome.org/PathwayBrowser/#/R-GGA-2213205 Type XII and XIV collagens associate with type I and type II fibrils IEA Gallus gallus A0A1D5PYU1 R-GGA-2243926 https://reactome.org/PathwayBrowser/#/R-GGA-2243926 Formation of histidino-hydroxylysinonorleucine cross-links IEA Gallus gallus A0A1D5PYU1 R-GGA-2243931 https://reactome.org/PathwayBrowser/#/R-GGA-2243931 Formation of dehydro-lysinonorleucine cross-links IEA Gallus gallus A0A1D5PYU1 R-GGA-2250301 https://reactome.org/PathwayBrowser/#/R-GGA-2250301 Formation of lysyl-pyrrole cross-links IEA Gallus gallus A0A1D5PYU1 R-GGA-2327909 https://reactome.org/PathwayBrowser/#/R-GGA-2327909 DCN binds collagen I, II, III, VI fibrils IEA Gallus gallus A0A1D5PYU1 R-GGA-2395223 https://reactome.org/PathwayBrowser/#/R-GGA-2395223 Formation of hydroxylysyl-pyridinoline cross-links IEA Gallus gallus A0A1D5PYU1 R-GGA-2395257 https://reactome.org/PathwayBrowser/#/R-GGA-2395257 Formation of dehydro-hydroxylysino-norleucine cross-links IEA Gallus gallus A0A1D5PYU1 R-GGA-2395302 https://reactome.org/PathwayBrowser/#/R-GGA-2395302 Formation of hydroxylysino-5-ketonorleucine cross-links IEA Gallus gallus A0A1D5PYU1 R-GGA-2395314 https://reactome.org/PathwayBrowser/#/R-GGA-2395314 Formation of lysino-5-ketonorleucine cross-links IEA Gallus gallus A0A1D5PYU1 R-GGA-2395322 https://reactome.org/PathwayBrowser/#/R-GGA-2395322 Formation of lysyl-pyridinoline cross-links IEA Gallus gallus A0A1D5PYU1 R-GGA-2395324 https://reactome.org/PathwayBrowser/#/R-GGA-2395324 Formation of hydroxylysyl-pyrrole cross-links IEA Gallus gallus A0A1D5PYU1 R-GGA-2395340 https://reactome.org/PathwayBrowser/#/R-GGA-2395340 Formation of hydroxyallysine by LOX IEA Gallus gallus A0A1D5PYU1 R-GGA-2424243 https://reactome.org/PathwayBrowser/#/R-GGA-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Gallus gallus A0A1D5PYU1 R-GGA-2424252 https://reactome.org/PathwayBrowser/#/R-GGA-2424252 COMP binds collagen, fibronectin, aggrecan and matrilins IEA Gallus gallus A0A1D5PYU1 R-GGA-2465890 https://reactome.org/PathwayBrowser/#/R-GGA-2465890 DDR2 binds collagen type I, II, III, V, X fibrils IEA Gallus gallus A0A1D5PYU1 R-GGA-2473596 https://reactome.org/PathwayBrowser/#/R-GGA-2473596 Collagen type I degradation by MMP15 IEA Gallus gallus A0A1D5PYU1 R-GGA-429529 https://reactome.org/PathwayBrowser/#/R-GGA-429529 Thrombin binding to GP1b:IX:V IEA Gallus gallus A0A1D5PYU1 R-GGA-430073 https://reactome.org/PathwayBrowser/#/R-GGA-430073 GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress IEA Gallus gallus A0A1D5PYU1 R-GGA-430076 https://reactome.org/PathwayBrowser/#/R-GGA-430076 GP1b-IX-V binds 14-3-3-zeta IEA Gallus gallus A0A1D5PYU1 R-GGA-443402 https://reactome.org/PathwayBrowser/#/R-GGA-443402 GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K IEA Gallus gallus A0A1D5PYU1 R-GGA-443418 https://reactome.org/PathwayBrowser/#/R-GGA-443418 GP1b signaling involves c-Src IEA Gallus gallus A0A1D5PYU1 R-GGA-8874079 https://reactome.org/PathwayBrowser/#/R-GGA-8874079 PTK2 binds activated MET IEA Gallus gallus A0A1D5PYU1 R-GGA-8944214 https://reactome.org/PathwayBrowser/#/R-GGA-8944214 Association of procollagen type I IEA Gallus gallus A0A1D5PYU1 R-GGA-8948228 https://reactome.org/PathwayBrowser/#/R-GGA-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Gallus gallus A0A1D5PYU1 R-GGA-8948231 https://reactome.org/PathwayBrowser/#/R-GGA-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Gallus gallus A0A1D5PYU1 R-GGA-8948232 https://reactome.org/PathwayBrowser/#/R-GGA-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Gallus gallus A0A1D5PYU1 R-GGA-8948234 https://reactome.org/PathwayBrowser/#/R-GGA-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Gallus gallus A0A1D5PYU1 R-GGA-9822539 https://reactome.org/PathwayBrowser/#/R-GGA-9822539 VWF multimer binds to collagen type I IEA Gallus gallus A0A1D5PYU1 R-GGA-9823065 https://reactome.org/PathwayBrowser/#/R-GGA-9823065 GPIb:IX:V binds to VWF multimer:collagen IEA Gallus gallus A0A1D5PYU9 R-GGA-6784959 https://reactome.org/PathwayBrowser/#/R-GGA-6784959 BPHL hydrolyses VACV to ACV IEA Gallus gallus A0A1D5PYV2 R-GGA-419001 https://reactome.org/PathwayBrowser/#/R-GGA-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Gallus gallus A0A1D5PYV2 R-GGA-419002 https://reactome.org/PathwayBrowser/#/R-GGA-419002 Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin IEA Gallus gallus A0A1D5PYY1 R-GGA-1971487 https://reactome.org/PathwayBrowser/#/R-GGA-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Gallus gallus A0A1D5PYY1 R-GGA-1971491 https://reactome.org/PathwayBrowser/#/R-GGA-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Gallus gallus A0A1D5PYY2 R-GGA-165680 https://reactome.org/PathwayBrowser/#/R-GGA-165680 Formation of active mTORC1 complex IEA Gallus gallus A0A1D5PYY2 R-GGA-165692 https://reactome.org/PathwayBrowser/#/R-GGA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Gallus gallus A0A1D5PYY2 R-GGA-165718 https://reactome.org/PathwayBrowser/#/R-GGA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Gallus gallus A0A1D5PYY2 R-GGA-377186 https://reactome.org/PathwayBrowser/#/R-GGA-377186 Activated Akt1 phosphorylates AKT1S1 (PRAS40) IEA Gallus gallus A0A1D5PYY2 R-GGA-380979 https://reactome.org/PathwayBrowser/#/R-GGA-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Gallus gallus A0A1D5PYY2 R-GGA-447074 https://reactome.org/PathwayBrowser/#/R-GGA-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Gallus gallus A0A1D5PYY2 R-GGA-5653968 https://reactome.org/PathwayBrowser/#/R-GGA-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Gallus gallus A0A1D5PYY2 R-GGA-5653974 https://reactome.org/PathwayBrowser/#/R-GGA-5653974 Ragulator binds Rag dimers IEA Gallus gallus A0A1D5PYY2 R-GGA-5672010 https://reactome.org/PathwayBrowser/#/R-GGA-5672010 Active MTORC1 phosphorylates ULK1 IEA Gallus gallus A0A1D5PYY2 R-GGA-5672017 https://reactome.org/PathwayBrowser/#/R-GGA-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Gallus gallus A0A1D5PYY2 R-GGA-5672817 https://reactome.org/PathwayBrowser/#/R-GGA-5672817 Active MTORC1 binds the ULK1 complex IEA Gallus gallus A0A1D5PYY2 R-GGA-5672824 https://reactome.org/PathwayBrowser/#/R-GGA-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Gallus gallus A0A1D5PYY2 R-GGA-5672828 https://reactome.org/PathwayBrowser/#/R-GGA-5672828 mTORC1 phosphorylates AKT1S1 IEA Gallus gallus A0A1D5PYY2 R-GGA-5673768 https://reactome.org/PathwayBrowser/#/R-GGA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Gallus gallus A0A1D5PYY2 R-GGA-5675790 https://reactome.org/PathwayBrowser/#/R-GGA-5675790 MTORC1 dissociates from ULK complex IEA Gallus gallus A0A1D5PYY2 R-GGA-6798747 https://reactome.org/PathwayBrowser/#/R-GGA-6798747 Exocytosis of tertiary granule membrane proteins IEA Gallus gallus A0A1D5PYY2 R-GGA-6799350 https://reactome.org/PathwayBrowser/#/R-GGA-6799350 Exocytosis of specific granule membrane proteins IEA Gallus gallus A0A1D5PYY2 R-GGA-8944454 https://reactome.org/PathwayBrowser/#/R-GGA-8944454 mTORC1 phosphorylates MAF1 IEA Gallus gallus A0A1D5PYY2 R-GGA-8944457 https://reactome.org/PathwayBrowser/#/R-GGA-8944457 MAF1 translocates to the nucleus IEA Gallus gallus A0A1D5PYY2 R-GGA-8952716 https://reactome.org/PathwayBrowser/#/R-GGA-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Gallus gallus A0A1D5PYY2 R-GGA-8952726 https://reactome.org/PathwayBrowser/#/R-GGA-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Gallus gallus A0A1D5PYY2 R-GGA-9639286 https://reactome.org/PathwayBrowser/#/R-GGA-9639286 RRAGC,D exchanges GTP for GDP IEA Gallus gallus A0A1D5PYY2 R-GGA-9640167 https://reactome.org/PathwayBrowser/#/R-GGA-9640167 RRAGA,B exchanges GDP for GTP IEA Gallus gallus A0A1D5PYY2 R-GGA-9640168 https://reactome.org/PathwayBrowser/#/R-GGA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Gallus gallus A0A1D5PYY2 R-GGA-9640175 https://reactome.org/PathwayBrowser/#/R-GGA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Gallus gallus A0A1D5PYY2 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus A0A1D5PYY2 R-GGA-9645598 https://reactome.org/PathwayBrowser/#/R-GGA-9645598 RRAGC,D hydrolyzes GTP IEA Gallus gallus A0A1D5PYY2 R-GGA-9645608 https://reactome.org/PathwayBrowser/#/R-GGA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Gallus gallus A0A1D5PYY2 R-GGA-9646468 https://reactome.org/PathwayBrowser/#/R-GGA-9646468 mTORC1 binds RHEB:GTP IEA Gallus gallus A0A1D5PYY5 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1D5PYY5 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1D5PYY5 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1D5PYY5 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1D5PYY5 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1D5PYZ2 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus A0A1D5PZ00 R-GGA-481007 https://reactome.org/PathwayBrowser/#/R-GGA-481007 Exocytosis of platelet alpha granule contents IEA Gallus gallus A0A1D5PZ18 R-GGA-443978 https://reactome.org/PathwayBrowser/#/R-GGA-443978 Receptor CCR11 binds CCL19, CCL21 & CCL25 IEA Gallus gallus A0A1D5PZ39 R-GGA-8855617 https://reactome.org/PathwayBrowser/#/R-GGA-8855617 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 IEA Gallus gallus A0A1D5PZ41 R-GGA-421831 https://reactome.org/PathwayBrowser/#/R-GGA-421831 trans-Golgi Network Coat Assembly IEA Gallus gallus A0A1D5PZ41 R-GGA-421835 https://reactome.org/PathwayBrowser/#/R-GGA-421835 trans-Golgi Network Vesicle Scission IEA Gallus gallus A0A1D5PZ45 R-GGA-3965444 https://reactome.org/PathwayBrowser/#/R-GGA-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Gallus gallus A0A1D5PZ45 R-GGA-3965447 https://reactome.org/PathwayBrowser/#/R-GGA-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Gallus gallus A0A1D5PZ45 R-GGA-4086392 https://reactome.org/PathwayBrowser/#/R-GGA-4086392 PDE6 hydrolyses cGMP to GMP IEA Gallus gallus A0A1D5PZ45 R-GGA-420883 https://reactome.org/PathwayBrowser/#/R-GGA-420883 Opsins act as GEFs for G alpha-t IEA Gallus gallus A0A1D5PZ45 R-GGA-8982637 https://reactome.org/PathwayBrowser/#/R-GGA-8982637 Opsins binds G alpha-t IEA Gallus gallus A0A1D5PZ45 R-GGA-8982640 https://reactome.org/PathwayBrowser/#/R-GGA-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Gallus gallus A0A1D5PZ51 R-GGA-399944 https://reactome.org/PathwayBrowser/#/R-GGA-399944 Phosphorylation of CRMPs by Cdk5 IEA Gallus gallus A0A1D5PZ51 R-GGA-399947 https://reactome.org/PathwayBrowser/#/R-GGA-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Gallus gallus A0A1D5PZ51 R-GGA-399951 https://reactome.org/PathwayBrowser/#/R-GGA-399951 Phosphorylation of CRMPs by GSK3beta IEA Gallus gallus A0A1D5PZ59 R-GGA-111439 https://reactome.org/PathwayBrowser/#/R-GGA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Gallus gallus A0A1D5PZ59 R-GGA-158441 https://reactome.org/PathwayBrowser/#/R-GGA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PZ59 R-GGA-158447 https://reactome.org/PathwayBrowser/#/R-GGA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Gallus gallus A0A1D5PZ59 R-GGA-158481 https://reactome.org/PathwayBrowser/#/R-GGA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1D5PZ59 R-GGA-158484 https://reactome.org/PathwayBrowser/#/R-GGA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Gallus gallus A0A1D5PZ59 R-GGA-159046 https://reactome.org/PathwayBrowser/#/R-GGA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Gallus gallus A0A1D5PZ59 R-GGA-159050 https://reactome.org/PathwayBrowser/#/R-GGA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Gallus gallus A0A1D5PZ59 R-GGA-170825 https://reactome.org/PathwayBrowser/#/R-GGA-170825 NPC exports GCK1 from nucleus IEA Gallus gallus A0A1D5PZ59 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1D5PZ59 R-GGA-2990880 https://reactome.org/PathwayBrowser/#/R-GGA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Gallus gallus A0A1D5PZ59 R-GGA-2990882 https://reactome.org/PathwayBrowser/#/R-GGA-2990882 CDK1 phosphorylates NUP98 IEA Gallus gallus A0A1D5PZ59 R-GGA-4551649 https://reactome.org/PathwayBrowser/#/R-GGA-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Gallus gallus A0A1D5PZ59 R-GGA-4551679 https://reactome.org/PathwayBrowser/#/R-GGA-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Gallus gallus A0A1D5PZ59 R-GGA-4615872 https://reactome.org/PathwayBrowser/#/R-GGA-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Gallus gallus A0A1D5PZ59 R-GGA-4615987 https://reactome.org/PathwayBrowser/#/R-GGA-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Gallus gallus A0A1D5PZ59 R-GGA-4655355 https://reactome.org/PathwayBrowser/#/R-GGA-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Gallus gallus A0A1D5PZ59 R-GGA-5228523 https://reactome.org/PathwayBrowser/#/R-GGA-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Gallus gallus A0A1D5PZ59 R-GGA-5578744 https://reactome.org/PathwayBrowser/#/R-GGA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Gallus gallus A0A1D5PZ59 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1D5PZ59 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1D5PZ59 R-GGA-77587 https://reactome.org/PathwayBrowser/#/R-GGA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Gallus gallus A0A1D5PZ59 R-GGA-9634169 https://reactome.org/PathwayBrowser/#/R-GGA-9634169 POM121 and NDC1 bind the Nup93 complex IEA Gallus gallus A0A1D5PZ75 R-GGA-1614544 https://reactome.org/PathwayBrowser/#/R-GGA-1614544 Sulfite is oxidized to sulfate IEA Gallus gallus A0A1D5PZ77 R-GGA-1602466 https://reactome.org/PathwayBrowser/#/R-GGA-1602466 Activation of MT-MMPs by FURIN IEA Gallus gallus A0A1D5PZ77 R-GGA-1605825 https://reactome.org/PathwayBrowser/#/R-GGA-1605825 MT-MMPs are sorted to the plasma membrane IEA Gallus gallus A0A1D5PZ78 R-GGA-8854173 https://reactome.org/PathwayBrowser/#/R-GGA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Gallus gallus A0A1D5PZ80 R-GGA-216064 https://reactome.org/PathwayBrowser/#/R-GGA-216064 Interaction of integrin alpha8beta1 with Tenascin-C IEA Gallus gallus A0A1D5PZ80 R-GGA-216068 https://reactome.org/PathwayBrowser/#/R-GGA-216068 Interaction of integrin alpha9beta1 with Tenascin-C IEA Gallus gallus A0A1D5PZ80 R-GGA-2424246 https://reactome.org/PathwayBrowser/#/R-GGA-2424246 Tenascins C, R, (X, N) bind lecticans IEA Gallus gallus A0A1D5PZ80 R-GGA-265426 https://reactome.org/PathwayBrowser/#/R-GGA-265426 Interaction of integrin alphaVbeta3 with Tenascin IEA Gallus gallus A0A1D5PZ80 R-GGA-2681667 https://reactome.org/PathwayBrowser/#/R-GGA-2681667 TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 IEA Gallus gallus A0A1D5PZ80 R-GGA-2681681 https://reactome.org/PathwayBrowser/#/R-GGA-2681681 Tenascins C, R, (X, N) bind fibronectin matrix IEA Gallus gallus A0A1D5PZ80 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1D5PZ84 R-GGA-2465940 https://reactome.org/PathwayBrowser/#/R-GGA-2465940 atRAL is reduced to atROL IEA Gallus gallus A0A1D5PZ84 R-GGA-5419165 https://reactome.org/PathwayBrowser/#/R-GGA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Gallus gallus A0A1D5PZ85 R-GGA-1236943 https://reactome.org/PathwayBrowser/#/R-GGA-1236943 Loading of antigen peptide onto MHC class I molecule IEA Gallus gallus A0A1D5PZ85 R-GGA-1236954 https://reactome.org/PathwayBrowser/#/R-GGA-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Gallus gallus A0A1D5PZ85 R-GGA-1236964 https://reactome.org/PathwayBrowser/#/R-GGA-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Gallus gallus A0A1D5PZ85 R-GGA-1236965 https://reactome.org/PathwayBrowser/#/R-GGA-1236965 Export of peptide loaded MHC class I complex to PM IEA Gallus gallus A0A1D5PZ85 R-GGA-198955 https://reactome.org/PathwayBrowser/#/R-GGA-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Gallus gallus A0A1D5PZ85 R-GGA-199062 https://reactome.org/PathwayBrowser/#/R-GGA-199062 KLRC1:KLRD1 heterodimer interacts with HLA-E IEA Gallus gallus A0A1D5PZ85 R-GGA-210289 https://reactome.org/PathwayBrowser/#/R-GGA-210289 Recruitment of SYK to p-DAP12 IEA Gallus gallus A0A1D5PZ85 R-GGA-2395412 https://reactome.org/PathwayBrowser/#/R-GGA-2395412 Phosphorylation of SYK IEA Gallus gallus A0A1D5PZ85 R-GGA-2396594 https://reactome.org/PathwayBrowser/#/R-GGA-2396594 Phosphorylation of SLP-76 by p-SYK IEA Gallus gallus A0A1D5PZ85 R-GGA-2424480 https://reactome.org/PathwayBrowser/#/R-GGA-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1D5PZ85 R-GGA-2424482 https://reactome.org/PathwayBrowser/#/R-GGA-2424482 p85 regulatory unit of PI3K binds p-6Y-SYK IEA Gallus gallus A0A1D5PZ85 R-GGA-2424484 https://reactome.org/PathwayBrowser/#/R-GGA-2424484 Phosphorylation of BTK by p-SYK IEA Gallus gallus A0A1D5PZ85 R-GGA-2424486 https://reactome.org/PathwayBrowser/#/R-GGA-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Gallus gallus A0A1D5PZ85 R-GGA-2424487 https://reactome.org/PathwayBrowser/#/R-GGA-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Gallus gallus A0A1D5PZ85 R-GGA-5691154 https://reactome.org/PathwayBrowser/#/R-GGA-5691154 HFE binds TFRC dimer IEA Gallus gallus A0A1D5PZ85 R-GGA-6798739 https://reactome.org/PathwayBrowser/#/R-GGA-6798739 Exocytosis of azurophil granule membrane proteins IEA Gallus gallus A0A1D5PZ85 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1D5PZ85 R-GGA-8863973 https://reactome.org/PathwayBrowser/#/R-GGA-8863973 Fusion of ERC and phagosome IEA Gallus gallus A0A1D5PZ85 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus A0A1D5PZ85 R-GGA-8951499 https://reactome.org/PathwayBrowser/#/R-GGA-8951499 Loading of antigenic peptides on to class I MHC IEA Gallus gallus A0A1D5PZ85 R-GGA-983138 https://reactome.org/PathwayBrowser/#/R-GGA-983138 Transport of MHC heterotrimer to ER exit site IEA Gallus gallus A0A1D5PZ85 R-GGA-983145 https://reactome.org/PathwayBrowser/#/R-GGA-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Gallus gallus A0A1D5PZ85 R-GGA-983146 https://reactome.org/PathwayBrowser/#/R-GGA-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Gallus gallus A0A1D5PZ85 R-GGA-983421 https://reactome.org/PathwayBrowser/#/R-GGA-983421 Journey of cargo through Golgi complex IEA Gallus gallus A0A1D5PZ85 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus A0A1D5PZ85 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus A0A1D5PZ85 R-GGA-983425 https://reactome.org/PathwayBrowser/#/R-GGA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Gallus gallus A0A1D5PZ85 R-GGA-983427 https://reactome.org/PathwayBrowser/#/R-GGA-983427 Expression of peptide bound class I MHC on cell surface IEA Gallus gallus A0A1D5PZ96 R-GGA-3108203 https://reactome.org/PathwayBrowser/#/R-GGA-3108203 PRC1 SUMOylates CTBP1 with SUMO2,3 IEA Gallus gallus A0A1D5PZ96 R-GGA-3108209 https://reactome.org/PathwayBrowser/#/R-GGA-3108209 PRC1 SUMOylates CTBP1 with SUMO1 IEA Gallus gallus A0A1D5PZ96 R-GGA-3229089 https://reactome.org/PathwayBrowser/#/R-GGA-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Gallus gallus A0A1D5PZ96 R-GGA-3229102 https://reactome.org/PathwayBrowser/#/R-GGA-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Gallus gallus A0A1D5PZ96 R-GGA-3296126 https://reactome.org/PathwayBrowser/#/R-GGA-3296126 CBX4, UHRF2 SUMOylate ZNF131 with SUMO1 IEA Gallus gallus A0A1D5PZ96 R-GGA-3927824 https://reactome.org/PathwayBrowser/#/R-GGA-3927824 PRC1 SUMOylates CASP8AP2 with SUMO1 IEA Gallus gallus A0A1D5PZ96 R-GGA-4551655 https://reactome.org/PathwayBrowser/#/R-GGA-4551655 CBX4 SUMOylates BMI1 in PRC1 with SUMO1 IEA Gallus gallus A0A1D5PZ96 R-GGA-4551727 https://reactome.org/PathwayBrowser/#/R-GGA-4551727 CBX4 SUMOylates CBX4 in PRC1 with SUMO1 IEA Gallus gallus A0A1D5PZ96 R-GGA-4570463 https://reactome.org/PathwayBrowser/#/R-GGA-4570463 CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 IEA Gallus gallus A0A1D5PZ96 R-GGA-4570499 https://reactome.org/PathwayBrowser/#/R-GGA-4570499 CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 IEA Gallus gallus A0A1D5PZ96 R-GGA-8937989 https://reactome.org/PathwayBrowser/#/R-GGA-8937989 RUNX1 binds PRC1 complexes IEA Gallus gallus A0A1D5PZ96 R-GGA-8943817 https://reactome.org/PathwayBrowser/#/R-GGA-8943817 MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter IEA Gallus gallus A0A1D5PZA4 R-GGA-204824 https://reactome.org/PathwayBrowser/#/R-GGA-204824 Interaction of Tie2 and Ang4 IEA Gallus gallus A0A1D5PZB7 R-GGA-418436 https://reactome.org/PathwayBrowser/#/R-GGA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Gallus gallus A0A1D5PZB7 R-GGA-9033235 https://reactome.org/PathwayBrowser/#/R-GGA-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1D5PZB7 R-GGA-9033236 https://reactome.org/PathwayBrowser/#/R-GGA-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Gallus gallus A0A1D5PZC6 R-GGA-428127 https://reactome.org/PathwayBrowser/#/R-GGA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Gallus gallus A0A1D5PZD4 R-GGA-1678842 https://reactome.org/PathwayBrowser/#/R-GGA-1678842 Competitive inhibition of translation initiation by ISGylated 4EHP IEA Gallus gallus A0A1D5PZD4 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1D5PZD4 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1D5PZD4 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1D5PZD4 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1D5PZE0 R-GGA-73757 https://reactome.org/PathwayBrowser/#/R-GGA-73757 Binding of RRN3 to RNA Polymerase I IEA Gallus gallus A0A1D5PZE0 R-GGA-73758 https://reactome.org/PathwayBrowser/#/R-GGA-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Gallus gallus A0A1D5PZE0 R-GGA-73769 https://reactome.org/PathwayBrowser/#/R-GGA-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Gallus gallus A0A1D5PZF7 R-GGA-429101 https://reactome.org/PathwayBrowser/#/R-GGA-429101 HMIT co-transports myo-inositol with a proton IEA Gallus gallus A0A1D5PZG1 R-GGA-389821 https://reactome.org/PathwayBrowser/#/R-GGA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Gallus gallus A0A1D5PZG1 R-GGA-9033235 https://reactome.org/PathwayBrowser/#/R-GGA-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1D5PZG1 R-GGA-9033236 https://reactome.org/PathwayBrowser/#/R-GGA-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Gallus gallus A0A1D5PZG6 R-GGA-9821368 https://reactome.org/PathwayBrowser/#/R-GGA-9821368 AKAP8L binds MLL1 complex IEA Gallus gallus A0A1D5PZH3 R-GGA-1605624 https://reactome.org/PathwayBrowser/#/R-GGA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Gallus gallus A0A1D5PZH3 R-GGA-1606312 https://reactome.org/PathwayBrowser/#/R-GGA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Gallus gallus A0A1D5PZH3 R-GGA-1630306 https://reactome.org/PathwayBrowser/#/R-GGA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Gallus gallus A0A1D5PZH3 R-GGA-2090079 https://reactome.org/PathwayBrowser/#/R-GGA-2090079 GLB1 hydrolyses linker chain(2) IEA Gallus gallus A0A1D5PZJ4 R-GGA-391266 https://reactome.org/PathwayBrowser/#/R-GGA-391266 Association of CCT/TriC with sphingosine kinase 1 IEA Gallus gallus A0A1D5PZJ4 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1D5PZJ4 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5PZJ4 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1D5PZJ4 R-GGA-6814119 https://reactome.org/PathwayBrowser/#/R-GGA-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Gallus gallus A0A1D5PZJ4 R-GGA-6814120 https://reactome.org/PathwayBrowser/#/R-GGA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Gallus gallus A0A1D5PZJ4 R-GGA-6814121 https://reactome.org/PathwayBrowser/#/R-GGA-6814121 PDCL binds G-protein beta and TRiC/CCT IEA Gallus gallus A0A1D5PZJ4 R-GGA-6814124 https://reactome.org/PathwayBrowser/#/R-GGA-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Gallus gallus A0A1D5PZJ4 R-GGA-8850527 https://reactome.org/PathwayBrowser/#/R-GGA-8850527 PDCL releases folded G-beta from TRiC/CCT IEA Gallus gallus A0A1D5PZJ4 R-GGA-8850529 https://reactome.org/PathwayBrowser/#/R-GGA-8850529 RGS proteins bind GNB5 and CCT/TRiC IEA Gallus gallus A0A1D5PZJ4 R-GGA-8850534 https://reactome.org/PathwayBrowser/#/R-GGA-8850534 PDCL promotes G-protein beta 5 folding IEA Gallus gallus A0A1D5PZJ4 R-GGA-8850539 https://reactome.org/PathwayBrowser/#/R-GGA-8850539 Release of GNB5:RGS dimers from CCT/TRiC IEA Gallus gallus A0A1D5PZJ5 R-GGA-8850846 https://reactome.org/PathwayBrowser/#/R-GGA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Gallus gallus A0A1D5PZJ5 R-GGA-8850854 https://reactome.org/PathwayBrowser/#/R-GGA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Gallus gallus A0A1D5PZK7 R-GGA-8933547 https://reactome.org/PathwayBrowser/#/R-GGA-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Gallus gallus A0A1D5PZL8 R-GGA-1296127 https://reactome.org/PathwayBrowser/#/R-GGA-1296127 Activation of voltage gated Potassium channels IEA Gallus gallus A0A1D5PZL8 R-GGA-381713 https://reactome.org/PathwayBrowser/#/R-GGA-381713 Potassium voltage-gated channels close in reponse to PKA IEA Gallus gallus A0A1D5PZM2 R-GGA-9645598 https://reactome.org/PathwayBrowser/#/R-GGA-9645598 RRAGC,D hydrolyzes GTP IEA Gallus gallus A0A1D5PZM5 R-GGA-5683384 https://reactome.org/PathwayBrowser/#/R-GGA-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Gallus gallus A0A1D5PZM5 R-GGA-5683385 https://reactome.org/PathwayBrowser/#/R-GGA-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Gallus gallus A0A1D5PZM5 R-GGA-5683735 https://reactome.org/PathwayBrowser/#/R-GGA-5683735 CHEK2 is recruited to DNA DSBs IEA Gallus gallus A0A1D5PZM5 R-GGA-5683801 https://reactome.org/PathwayBrowser/#/R-GGA-5683801 CHEK2 phosphorylates BRCA1 IEA Gallus gallus A0A1D5PZM5 R-GGA-5684052 https://reactome.org/PathwayBrowser/#/R-GGA-5684052 PIAS4 SUMOylates MDC1 IEA Gallus gallus A0A1D5PZM5 R-GGA-5686685 https://reactome.org/PathwayBrowser/#/R-GGA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Gallus gallus A0A1D5PZM5 R-GGA-5691411 https://reactome.org/PathwayBrowser/#/R-GGA-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Gallus gallus A0A1D5PZM5 R-GGA-5693551 https://reactome.org/PathwayBrowser/#/R-GGA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Gallus gallus A0A1D5PZM5 R-GGA-69891 https://reactome.org/PathwayBrowser/#/R-GGA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Gallus gallus A0A1D5PZM8 R-GGA-6785342 https://reactome.org/PathwayBrowser/#/R-GGA-6785342 FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex IEA Gallus gallus A0A1D5PZM8 R-GGA-6785361 https://reactome.org/PathwayBrowser/#/R-GGA-6785361 Monoubiquitination of FANCD2:FANCI IEA Gallus gallus A0A1D5PZM8 R-GGA-6786171 https://reactome.org/PathwayBrowser/#/R-GGA-6786171 FANCD2 deubiquitination by USP1:WDR48 IEA Gallus gallus A0A1D5PZM8 R-GGA-6788385 https://reactome.org/PathwayBrowser/#/R-GGA-6788385 The complex of ATR and ATRIP is recruited to ICL-DNA IEA Gallus gallus A0A1D5PZM8 R-GGA-6788392 https://reactome.org/PathwayBrowser/#/R-GGA-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Gallus gallus A0A1D5PZM8 R-GGA-9835411 https://reactome.org/PathwayBrowser/#/R-GGA-9835411 FA core complex:HSP70s binds PKR IEA Gallus gallus A0A1D5PZQ0 R-GGA-3878123 https://reactome.org/PathwayBrowser/#/R-GGA-3878123 Initiation of SAHF formation IEA Gallus gallus A0A1D5PZQ5 R-GGA-8877612 https://reactome.org/PathwayBrowser/#/R-GGA-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Gallus gallus A0A1D5PZQ5 R-GGA-8933446 https://reactome.org/PathwayBrowser/#/R-GGA-8933446 Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling IEA Gallus gallus A0A1D5PZQ5 R-GGA-8933452 https://reactome.org/PathwayBrowser/#/R-GGA-8933452 YWHAE dimer binds phosphorylated DENND1 proteins IEA Gallus gallus A0A1D5PZR3 R-GGA-9033235 https://reactome.org/PathwayBrowser/#/R-GGA-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1D5PZR3 R-GGA-9033236 https://reactome.org/PathwayBrowser/#/R-GGA-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Gallus gallus A0A1D5PZS0 R-GGA-6782069 https://reactome.org/PathwayBrowser/#/R-GGA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Gallus gallus A0A1D5PZS0 R-GGA-6782131 https://reactome.org/PathwayBrowser/#/R-GGA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5PZS0 R-GGA-6782138 https://reactome.org/PathwayBrowser/#/R-GGA-6782138 ERCC5 and RPA bind TC-NER site IEA Gallus gallus A0A1D5PZS0 R-GGA-6782204 https://reactome.org/PathwayBrowser/#/R-GGA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Gallus gallus A0A1D5PZS0 R-GGA-6782208 https://reactome.org/PathwayBrowser/#/R-GGA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Gallus gallus A0A1D5PZS0 R-GGA-6782211 https://reactome.org/PathwayBrowser/#/R-GGA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Gallus gallus A0A1D5PZS0 R-GGA-6782227 https://reactome.org/PathwayBrowser/#/R-GGA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Gallus gallus A0A1D5PZS0 R-GGA-9684118 https://reactome.org/PathwayBrowser/#/R-GGA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1D5PZS0 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1D5PZS5 R-GGA-1964501 https://reactome.org/PathwayBrowser/#/R-GGA-1964501 Addition of galactose to Core 6 glycoprotein IEA Gallus gallus A0A1D5PZS5 R-GGA-1964505 https://reactome.org/PathwayBrowser/#/R-GGA-1964505 C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) IEA Gallus gallus A0A1D5PZS5 R-GGA-5694487 https://reactome.org/PathwayBrowser/#/R-GGA-5694487 A4GNT transfers GlcNAc to core 2 mucins IEA Gallus gallus A0A1D5PZS5 R-GGA-6786012 https://reactome.org/PathwayBrowser/#/R-GGA-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins IEA Gallus gallus A0A1D5PZS5 R-GGA-8858500 https://reactome.org/PathwayBrowser/#/R-GGA-8858500 CLEC10A binds Tn-MUC1 IEA Gallus gallus A0A1D5PZS5 R-GGA-913675 https://reactome.org/PathwayBrowser/#/R-GGA-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Gallus gallus A0A1D5PZS5 R-GGA-914005 https://reactome.org/PathwayBrowser/#/R-GGA-914005 Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein IEA Gallus gallus A0A1D5PZS5 R-GGA-914006 https://reactome.org/PathwayBrowser/#/R-GGA-914006 Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein IEA Gallus gallus A0A1D5PZS5 R-GGA-914008 https://reactome.org/PathwayBrowser/#/R-GGA-914008 Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein IEA Gallus gallus A0A1D5PZS5 R-GGA-914010 https://reactome.org/PathwayBrowser/#/R-GGA-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Gallus gallus A0A1D5PZS5 R-GGA-914012 https://reactome.org/PathwayBrowser/#/R-GGA-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Gallus gallus A0A1D5PZS5 R-GGA-914017 https://reactome.org/PathwayBrowser/#/R-GGA-914017 Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein IEA Gallus gallus A0A1D5PZS5 R-GGA-914018 https://reactome.org/PathwayBrowser/#/R-GGA-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Gallus gallus A0A1D5PZS5 R-GGA-977071 https://reactome.org/PathwayBrowser/#/R-GGA-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Gallus gallus A0A1D5PZS5 R-GGA-981497 https://reactome.org/PathwayBrowser/#/R-GGA-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Gallus gallus A0A1D5PZS5 R-GGA-981809 https://reactome.org/PathwayBrowser/#/R-GGA-981809 ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen IEA Gallus gallus A0A1D5PZS5 R-GGA-981814 https://reactome.org/PathwayBrowser/#/R-GGA-981814 ST6GALNAC2 transfers sialic acid to Core 1 mucins IEA Gallus gallus A0A1D5PZT0 R-GGA-964737 https://reactome.org/PathwayBrowser/#/R-GGA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus A0A1D5PZT0 R-GGA-964825 https://reactome.org/PathwayBrowser/#/R-GGA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus A0A1D5PZT0 R-GGA-964830 https://reactome.org/PathwayBrowser/#/R-GGA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus A0A1D5PZT4 R-GGA-1474146 https://reactome.org/PathwayBrowser/#/R-GGA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Gallus gallus A0A1D5PZT4 R-GGA-1474158 https://reactome.org/PathwayBrowser/#/R-GGA-1474158 GCHFR binds to GCH1 and negatively regulates its activity IEA Gallus gallus A0A1D5PZT6 R-GGA-425661 https://reactome.org/PathwayBrowser/#/R-GGA-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Gallus gallus A0A1D5PZU7 R-GGA-8877692 https://reactome.org/PathwayBrowser/#/R-GGA-8877692 PIN1 binds phosphorylated PIP4K2B IEA Gallus gallus A0A1D5PZU7 R-GGA-9626816 https://reactome.org/PathwayBrowser/#/R-GGA-9626816 PIN1 binds p-S345-NCF1 IEA Gallus gallus A0A1D5PZU7 R-GGA-9626817 https://reactome.org/PathwayBrowser/#/R-GGA-9626817 PKC phosphorylates NCF1 IEA Gallus gallus A0A1D5PZW8 R-GGA-3209159 https://reactome.org/PathwayBrowser/#/R-GGA-3209159 Phosphorylated ERF translocates to the cytosol IEA Gallus gallus A0A1D5PZX4 R-GGA-200680 https://reactome.org/PathwayBrowser/#/R-GGA-200680 SLC25A32 transports THF from cytosol to mitochondrial matrix IEA Gallus gallus A0A1D5PZX4 R-GGA-200720 https://reactome.org/PathwayBrowser/#/R-GGA-200720 SLC25A32 transports THF from mitochondrial matrix to cytosol IEA Gallus gallus A0A1D5PZX6 R-GGA-216076 https://reactome.org/PathwayBrowser/#/R-GGA-216076 VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 IEA Gallus gallus A0A1D5PZX6 R-GGA-2395320 https://reactome.org/PathwayBrowser/#/R-GGA-2395320 Latent TGF-beta-1 binds integrins IEA Gallus gallus A0A1D5PZX6 R-GGA-2396029 https://reactome.org/PathwayBrowser/#/R-GGA-2396029 Latent TGF-beta-3 binds integrins IEA Gallus gallus A0A1D5PZX7 R-GGA-205328 https://reactome.org/PathwayBrowser/#/R-GGA-205328 Interaction of other tyrosine kinases with p-KIT IEA Gallus gallus A0A1D5PZX7 R-GGA-399930 https://reactome.org/PathwayBrowser/#/R-GGA-399930 Activation of PAK by Rac1 IEA Gallus gallus A0A1D5PZX7 R-GGA-399939 https://reactome.org/PathwayBrowser/#/R-GGA-399939 Autophosphorylation of PAK IEA Gallus gallus A0A1D5PZX7 R-GGA-399947 https://reactome.org/PathwayBrowser/#/R-GGA-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Gallus gallus A0A1D5PZX7 R-GGA-399952 https://reactome.org/PathwayBrowser/#/R-GGA-399952 Phosphorylation of LIMK-1 by PAK IEA Gallus gallus A0A1D5PZZ4 R-GGA-2076611 https://reactome.org/PathwayBrowser/#/R-GGA-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Gallus gallus A0A1D5PZZ8 R-GGA-975814 https://reactome.org/PathwayBrowser/#/R-GGA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Gallus gallus A0A1D5Q004 R-GGA-390284 https://reactome.org/PathwayBrowser/#/R-GGA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Gallus gallus A0A1D5Q004 R-GGA-390291 https://reactome.org/PathwayBrowser/#/R-GGA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Gallus gallus A0A1D5Q004 R-GGA-9033235 https://reactome.org/PathwayBrowser/#/R-GGA-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1D5Q004 R-GGA-9033236 https://reactome.org/PathwayBrowser/#/R-GGA-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Gallus gallus A0A1D5Q008 R-GGA-532549 https://reactome.org/PathwayBrowser/#/R-GGA-532549 MPI isomerises Fru6P to Man6P IEA Gallus gallus A0A1D5Q032 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1D5RLK8 R-MMU-8850818 https://reactome.org/PathwayBrowser/#/R-MMU-8850818 SPINK9 binds KLK5 IEA Mus musculus A0A1D5RMC2 R-MMU-975040 https://reactome.org/PathwayBrowser/#/R-MMU-975040 KRAB-ZNF / KAP Interaction IEA Mus musculus A0A1D5RMN0 R-MMU-5690845 https://reactome.org/PathwayBrowser/#/R-MMU-5690845 TNIPs bind TNFAIP3 (A20) IEA Mus musculus A0A1D6UPQ1 R-GGA-448963 https://reactome.org/PathwayBrowser/#/R-GGA-448963 Interaction of MyoD:E protein with MEF2 IEA Gallus gallus A0A1D6UPQ1 R-GGA-8956568 https://reactome.org/PathwayBrowser/#/R-GGA-8956568 RUNX1 binds the core TAL1 complex IEA Gallus gallus A0A1D6UPQ2 R-GGA-9856465 https://reactome.org/PathwayBrowser/#/R-GGA-9856465 MLPH/MYRIP bind GGC-RAB27A and MYO5A IEA Gallus gallus A0A1D6UPQ7 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus A0A1D6UPQ7 R-GGA-390931 https://reactome.org/PathwayBrowser/#/R-GGA-390931 5-HT4, 6 and 7 receptors can bind serotonin IEA Gallus gallus A0A1D6UPQ9 R-GGA-426032 https://reactome.org/PathwayBrowser/#/R-GGA-426032 DAG is metabolized by DAGL to 2-AG IEA Gallus gallus A0A1D6UPR4 R-GGA-5694494 https://reactome.org/PathwayBrowser/#/R-GGA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Gallus gallus A0A1D6UPR6 R-GGA-8876696 https://reactome.org/PathwayBrowser/#/R-GGA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Gallus gallus A0A1D6UPS4 R-GGA-376419 https://reactome.org/PathwayBrowser/#/R-GGA-376419 Formation of NR-MED1 Coactivator Complex IEA Gallus gallus A0A1D6UPS4 R-GGA-382096 https://reactome.org/PathwayBrowser/#/R-GGA-382096 Formation of NR-NCOR Corepressor Complex IEA Gallus gallus A0A1D6UPS7 R-GGA-2161961 https://reactome.org/PathwayBrowser/#/R-GGA-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Gallus gallus A0A1D6UPS7 R-GGA-9024993 https://reactome.org/PathwayBrowser/#/R-GGA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Gallus gallus A0A1D6UPS7 R-GGA-9033235 https://reactome.org/PathwayBrowser/#/R-GGA-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1D6UPS7 R-GGA-9033236 https://reactome.org/PathwayBrowser/#/R-GGA-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Gallus gallus A0A1D6UPS7 R-GGA-9915968 https://reactome.org/PathwayBrowser/#/R-GGA-9915968 8,9-EET is hydrolysed to 8.9-DHET by EPHX2 IEA Gallus gallus A0A1D6UPS7 R-GGA-9915986 https://reactome.org/PathwayBrowser/#/R-GGA-9915986 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 IEA Gallus gallus A0A1D6UPS7 R-GGA-9915994 https://reactome.org/PathwayBrowser/#/R-GGA-9915994 14,15-EET is hydrolysed to 14,15-DHET by EPHX2 IEA Gallus gallus A0A1D6UPS9 R-GGA-75079 https://reactome.org/PathwayBrowser/#/R-GGA-75079 Formation of AT-AC C complex IEA Gallus gallus A0A1D6UPS9 R-GGA-75081 https://reactome.org/PathwayBrowser/#/R-GGA-75081 Formation of AT-AC B Complex IEA Gallus gallus A0A1D6UPS9 R-GGA-75082 https://reactome.org/PathwayBrowser/#/R-GGA-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Gallus gallus A0A1D6UPS9 R-GGA-75083 https://reactome.org/PathwayBrowser/#/R-GGA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Gallus gallus A0A1D6UPT6 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus A0A1D6UPT6 R-GGA-6799178 https://reactome.org/PathwayBrowser/#/R-GGA-6799178 Intermediate 1 binds HP subcomplex to form Intermediate 2 IEA Gallus gallus A0A1D6UPT6 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus A0A1D6UPT6 R-GGA-6799191 https://reactome.org/PathwayBrowser/#/R-GGA-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Gallus gallus A0A1D6UPT6 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus A0A1D6UPT6 R-GGA-6799202 https://reactome.org/PathwayBrowser/#/R-GGA-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Gallus gallus A0A1D6UPU4 R-GGA-8848338 https://reactome.org/PathwayBrowser/#/R-GGA-8848338 PNPLA4 hydrolyzes TAG IEA Gallus gallus A0A1D6UPU4 R-GGA-8848355 https://reactome.org/PathwayBrowser/#/R-GGA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Gallus gallus A0A1D6UPU5 R-GGA-1222376 https://reactome.org/PathwayBrowser/#/R-GGA-1222376 NOX2 generates superoxide from oxygen IEA Gallus gallus A0A1D6UPU5 R-GGA-1236967 https://reactome.org/PathwayBrowser/#/R-GGA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Gallus gallus A0A1D6UPU5 R-GGA-5218827 https://reactome.org/PathwayBrowser/#/R-GGA-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Gallus gallus A0A1D6UPU5 R-GGA-5218841 https://reactome.org/PathwayBrowser/#/R-GGA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Gallus gallus A0A1D6UPU5 R-GGA-5668605 https://reactome.org/PathwayBrowser/#/R-GGA-5668605 RAC2:GTP binds NOX2 complex IEA Gallus gallus A0A1D6UPU5 R-GGA-5668629 https://reactome.org/PathwayBrowser/#/R-GGA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Gallus gallus A0A1D6UPU5 R-GGA-6789092 https://reactome.org/PathwayBrowser/#/R-GGA-6789092 NOX2 generates superoxide anion from oxygen IEA Gallus gallus A0A1D6UPU5 R-GGA-6798747 https://reactome.org/PathwayBrowser/#/R-GGA-6798747 Exocytosis of tertiary granule membrane proteins IEA Gallus gallus A0A1D6UPU5 R-GGA-6799350 https://reactome.org/PathwayBrowser/#/R-GGA-6799350 Exocytosis of specific granule membrane proteins IEA Gallus gallus A0A1D6UPU5 R-GGA-6807557 https://reactome.org/PathwayBrowser/#/R-GGA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Gallus gallus A0A1D6UPU5 R-GGA-9013145 https://reactome.org/PathwayBrowser/#/R-GGA-9013145 RAC1 binds effectors at the plasma membrane IEA Gallus gallus A0A1D6UPU5 R-GGA-9014424 https://reactome.org/PathwayBrowser/#/R-GGA-9014424 RAC2 binds effectors at the phagocytic vesicle membrane IEA Gallus gallus A0A1D6UPU5 R-GGA-9018808 https://reactome.org/PathwayBrowser/#/R-GGA-9018808 RAC3 binds effectors at the plasma membrane IEA Gallus gallus A0A1D6UPU5 R-GGA-9626848 https://reactome.org/PathwayBrowser/#/R-GGA-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Gallus gallus A0A1D6Y7R2 R-GGA-111237 https://reactome.org/PathwayBrowser/#/R-GGA-111237 Formation of ADAR1 homodimer IEA Gallus gallus A0A1D6Y7R2 R-GGA-75090 https://reactome.org/PathwayBrowser/#/R-GGA-75090 Binding of ADAR1 homodimer to dsRNA duplex IEA Gallus gallus A0A1D6Y7R2 R-GGA-77614 https://reactome.org/PathwayBrowser/#/R-GGA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Gallus gallus A0A1D6Y7R2 R-GGA-9835944 https://reactome.org/PathwayBrowser/#/R-GGA-9835944 ADAR1 binds PKR IEA Gallus gallus A0A1I6CM72 R-CEL-5693925 https://reactome.org/PathwayBrowser/#/R-CEL-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc IEA Caenorhabditis elegans A0A1I6CM72 R-CEL-9603984 https://reactome.org/PathwayBrowser/#/R-CEL-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Caenorhabditis elegans A0A1I6CM72 R-CEL-9603986 https://reactome.org/PathwayBrowser/#/R-CEL-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Caenorhabditis elegans A0A1I6CM72 R-CEL-9605609 https://reactome.org/PathwayBrowser/#/R-CEL-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Caenorhabditis elegans A0A1I6CM72 R-CEL-9605644 https://reactome.org/PathwayBrowser/#/R-CEL-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Caenorhabditis elegans A0A1I6CM72 R-CEL-9605682 https://reactome.org/PathwayBrowser/#/R-CEL-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-1433471 https://reactome.org/PathwayBrowser/#/R-CEL-1433471 Activation of RAS by p-KIT bound SOS1 IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-1433508 https://reactome.org/PathwayBrowser/#/R-CEL-1433508 PKC alpha interacts with and phosphorylates KIT IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-1433514 https://reactome.org/PathwayBrowser/#/R-CEL-1433514 Synthesis of PIP3 from PIP2 by PI3K IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-1524186 https://reactome.org/PathwayBrowser/#/R-CEL-1524186 Phosphorylation of PLCgamma by PDGFR IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-186780 https://reactome.org/PathwayBrowser/#/R-CEL-186780 PI3-kinase binds to the active receptor IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-186786 https://reactome.org/PathwayBrowser/#/R-CEL-186786 Autophosphorylation of PDGF beta receptors IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-186800 https://reactome.org/PathwayBrowser/#/R-CEL-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-186819 https://reactome.org/PathwayBrowser/#/R-CEL-186819 SH2 domain of Src binds to the active receptor IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-186826 https://reactome.org/PathwayBrowser/#/R-CEL-186826 GRB2:SOS1 complex binds to the active receptor IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-186834 https://reactome.org/PathwayBrowser/#/R-CEL-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-205244 https://reactome.org/PathwayBrowser/#/R-CEL-205244 Recruitment of CBL to KIT IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-2316434 https://reactome.org/PathwayBrowser/#/R-CEL-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-380780 https://reactome.org/PathwayBrowser/#/R-CEL-380780 Activation of Src IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-380782 https://reactome.org/PathwayBrowser/#/R-CEL-380782 STAT binds to the active receptor IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-382056 https://reactome.org/PathwayBrowser/#/R-CEL-382056 Crk binds to the active PDGF receptor IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-382058 https://reactome.org/PathwayBrowser/#/R-CEL-382058 Nck binds to the active PDGF receptor IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-389083 https://reactome.org/PathwayBrowser/#/R-CEL-389083 Autophosphorylation of PDGF alpha receptors IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-389086 https://reactome.org/PathwayBrowser/#/R-CEL-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-4088281 https://reactome.org/PathwayBrowser/#/R-CEL-4088281 Endorepellin binds KDR (VEGFR2) IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-4420206 https://reactome.org/PathwayBrowser/#/R-CEL-4420206 Phosphorylation of SRC-1 IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-5218804 https://reactome.org/PathwayBrowser/#/R-CEL-5218804 p38 MAPK activation by VEGFR IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-5218806 https://reactome.org/PathwayBrowser/#/R-CEL-5218806 FYN autophosphorylates IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-5218812 https://reactome.org/PathwayBrowser/#/R-CEL-5218812 FYN phosphorylates PAK2 IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-5218814 https://reactome.org/PathwayBrowser/#/R-CEL-5218814 PAK2 autophorylates IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-5218819 https://reactome.org/PathwayBrowser/#/R-CEL-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-5218832 https://reactome.org/PathwayBrowser/#/R-CEL-5218832 CDC42:GTP binds PAK2 IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-5218836 https://reactome.org/PathwayBrowser/#/R-CEL-5218836 PTK2beta binds alphaVbeta3 IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-5218847 https://reactome.org/PathwayBrowser/#/R-CEL-5218847 PAK2 binds NCK IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-5218854 https://reactome.org/PathwayBrowser/#/R-CEL-5218854 p-Y420-FYN is phosphorylated on S21 IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-5357429 https://reactome.org/PathwayBrowser/#/R-CEL-5357429 AXL autophosphorylates on Y779 and Y821 IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-5357432 https://reactome.org/PathwayBrowser/#/R-CEL-5357432 AXL binds SRC-1 IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-5357479 https://reactome.org/PathwayBrowser/#/R-CEL-5357479 p-AXL binds PI3K IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-5672965 https://reactome.org/PathwayBrowser/#/R-CEL-5672965 RAS GEFs promote RAS nucleotide exchange IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-9607304 https://reactome.org/PathwayBrowser/#/R-CEL-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-9669854 https://reactome.org/PathwayBrowser/#/R-CEL-9669854 KIT binds type II TKIs IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-9674093 https://reactome.org/PathwayBrowser/#/R-CEL-9674093 PDGFRs bind type I TKI IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans A0A1I6CMA1 R-CEL-9681375 https://reactome.org/PathwayBrowser/#/R-CEL-9681375 KIT binds ripretinib IEA Caenorhabditis elegans A0A1I7Q3Z7 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A1I7Q3Z7 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A1I7Q3Z7 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A1I7Q3Z7 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A1I7Q3Z7 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1I7Q3Z7 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1I7Q3Z7 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1I7Q3Z7 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1I7Q3Z7 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1I7Q3Z7 R-GGA-2574840 https://reactome.org/PathwayBrowser/#/R-GGA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Gallus gallus A0A1I7Q3Z7 R-GGA-2574845 https://reactome.org/PathwayBrowser/#/R-GGA-2574845 AJUBA binds centrosome-associated AURKA IEA Gallus gallus A0A1I7Q3Z7 R-GGA-3000310 https://reactome.org/PathwayBrowser/#/R-GGA-3000310 AURKA phosphorylates PLK1 IEA Gallus gallus A0A1I7Q3Z7 R-GGA-3000319 https://reactome.org/PathwayBrowser/#/R-GGA-3000319 BORA binds PLK1 and AURKA IEA Gallus gallus A0A1I7Q3Z7 R-GGA-380272 https://reactome.org/PathwayBrowser/#/R-GGA-380272 Plk1-mediated phosphorylation of Nlp IEA Gallus gallus A0A1I7Q3Z7 R-GGA-380283 https://reactome.org/PathwayBrowser/#/R-GGA-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Gallus gallus A0A1I7Q3Z7 R-GGA-380294 https://reactome.org/PathwayBrowser/#/R-GGA-380294 Loss of C-Nap-1 from centrosomes IEA Gallus gallus A0A1I7Q3Z7 R-GGA-380311 https://reactome.org/PathwayBrowser/#/R-GGA-380311 Recruitment of Plk1 to centrosomes IEA Gallus gallus A0A1I7Q3Z7 R-GGA-380455 https://reactome.org/PathwayBrowser/#/R-GGA-380455 Recruitment of CDK11p58 to the centrosomes IEA Gallus gallus A0A1I7Q3Z7 R-GGA-380508 https://reactome.org/PathwayBrowser/#/R-GGA-380508 Translocation of NuMA to the centrosomes IEA Gallus gallus A0A1I7Q3Z7 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1I7Q3Z7 R-GGA-5626228 https://reactome.org/PathwayBrowser/#/R-GGA-5626228 The distal appendage proteins recruit TTBK2 IEA Gallus gallus A0A1I7Q3Z7 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1I7Q3Z7 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1I7Q3Z7 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A1I7Q3Z7 R-GGA-8853405 https://reactome.org/PathwayBrowser/#/R-GGA-8853405 TPX2 binds AURKA at centrosomes IEA Gallus gallus A0A1I7Q3Z7 R-GGA-8853419 https://reactome.org/PathwayBrowser/#/R-GGA-8853419 TPX2 promotes AURKA autophosphorylation IEA Gallus gallus A0A1I7Q3Z7 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1I7Q402 R-GGA-1168445 https://reactome.org/PathwayBrowser/#/R-GGA-1168445 PTP1B binds the GH receptor complex IEA Gallus gallus A0A1I7Q402 R-GGA-1169192 https://reactome.org/PathwayBrowser/#/R-GGA-1169192 PTP1B dephosphorylates GHR IEA Gallus gallus A0A1I7Q402 R-GGA-377643 https://reactome.org/PathwayBrowser/#/R-GGA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Gallus gallus A0A1I7Q402 R-GGA-6807027 https://reactome.org/PathwayBrowser/#/R-GGA-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Gallus gallus A0A1I7Q402 R-GGA-74733 https://reactome.org/PathwayBrowser/#/R-GGA-74733 Insulin receptor de-phosphorylation IEA Gallus gallus A0A1I7Q402 R-GGA-9865167 https://reactome.org/PathwayBrowser/#/R-GGA-9865167 PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) IEA Gallus gallus A0A1I7Q402 R-GGA-997311 https://reactome.org/PathwayBrowser/#/R-GGA-997311 Dephosphorylation of TYK2 by PTP1B IEA Gallus gallus A0A1I7Q405 R-GGA-5681987 https://reactome.org/PathwayBrowser/#/R-GGA-5681987 LC3 is cleaved by ATG4 IEA Gallus gallus A0A1I7Q405 R-GGA-5682377 https://reactome.org/PathwayBrowser/#/R-GGA-5682377 LC3 de-lipidation by ATG4 IEA Gallus gallus A0A1I7Q407 R-GGA-6781779 https://reactome.org/PathwayBrowser/#/R-GGA-6781779 USP13 deubiquitinates BECN1,USP10 IEA Gallus gallus A0A1I7Q407 R-GGA-6781899 https://reactome.org/PathwayBrowser/#/R-GGA-6781899 USP13 binds SIAH2 IEA Gallus gallus A0A1I7Q407 R-GGA-6781922 https://reactome.org/PathwayBrowser/#/R-GGA-6781922 USP13 binds UFD1L:SKP2 IEA Gallus gallus A0A1I7Q407 R-GGA-6807206 https://reactome.org/PathwayBrowser/#/R-GGA-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Gallus gallus A0A1I7Q410 R-GGA-6814555 https://reactome.org/PathwayBrowser/#/R-GGA-6814555 Integrator complex processes the 3' end of snRNA IEA Gallus gallus A0A1I7Q410 R-GGA-6814559 https://reactome.org/PathwayBrowser/#/R-GGA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Gallus gallus A0A1I7Q412 R-GGA-8851356 https://reactome.org/PathwayBrowser/#/R-GGA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Gallus gallus A0A1I7Q422 R-GGA-2404134 https://reactome.org/PathwayBrowser/#/R-GGA-2404134 RBP4:atROL binds TTR IEA Gallus gallus A0A1I7Q422 R-GGA-2453863 https://reactome.org/PathwayBrowser/#/R-GGA-2453863 STRA6 transports atROL from extracellular region to cytosol IEA Gallus gallus A0A1I7Q422 R-GGA-2453876 https://reactome.org/PathwayBrowser/#/R-GGA-2453876 TTR:RBP:atROL binds to STRA6 receptor IEA Gallus gallus A0A1I7Q422 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1I7Q423 R-GGA-9014467 https://reactome.org/PathwayBrowser/#/R-GGA-9014467 RHOG binds effectors at the ER membrane IEA Gallus gallus A0A1I7Q424 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1I7Q424 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1I7Q424 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1I7Q424 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1I7Q426 R-GGA-212222 https://reactome.org/PathwayBrowser/#/R-GGA-212222 PRC2 recruits DNA methyltransferases IEA Gallus gallus A0A1I7Q426 R-GGA-212252 https://reactome.org/PathwayBrowser/#/R-GGA-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Gallus gallus A0A1I7Q426 R-GGA-212263 https://reactome.org/PathwayBrowser/#/R-GGA-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Gallus gallus A0A1I7Q426 R-GGA-212269 https://reactome.org/PathwayBrowser/#/R-GGA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Gallus gallus A0A1I7Q426 R-GGA-3240295 https://reactome.org/PathwayBrowser/#/R-GGA-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Gallus gallus A0A1I7Q426 R-GGA-3662318 https://reactome.org/PathwayBrowser/#/R-GGA-3662318 Type B histone acetlytransferase complex acetylates histone H4 IEA Gallus gallus A0A1I7Q426 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus A0A1I7Q426 R-GGA-606287 https://reactome.org/PathwayBrowser/#/R-GGA-606287 RSF complex binds the centromere IEA Gallus gallus A0A1I7Q426 R-GGA-606289 https://reactome.org/PathwayBrowser/#/R-GGA-606289 New CENPA-containing nucleosomes are deposited at the centromere IEA Gallus gallus A0A1I7Q426 R-GGA-606326 https://reactome.org/PathwayBrowser/#/R-GGA-606326 HJURP:CENPA complex localizes to the centromere IEA Gallus gallus A0A1I7Q426 R-GGA-73739 https://reactome.org/PathwayBrowser/#/R-GGA-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter IEA Gallus gallus A0A1I7Q426 R-GGA-8943780 https://reactome.org/PathwayBrowser/#/R-GGA-8943780 SALL4 recruits NuRD to PTEN gene IEA Gallus gallus A0A1I7Q426 R-GGA-8943817 https://reactome.org/PathwayBrowser/#/R-GGA-8943817 MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter IEA Gallus gallus A0A1I7Q426 R-GGA-8952638 https://reactome.org/PathwayBrowser/#/R-GGA-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1I7Q426 R-GGA-8952639 https://reactome.org/PathwayBrowser/#/R-GGA-8952639 NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1I7Q426 R-GGA-8954110 https://reactome.org/PathwayBrowser/#/R-GGA-8954110 E2F6:TFDP1:EPC1 binds the PRC2 complex IEA Gallus gallus A0A1I7Q426 R-GGA-8955245 https://reactome.org/PathwayBrowser/#/R-GGA-8955245 CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus IEA Gallus gallus A0A1I7Q426 R-GGA-8956045 https://reactome.org/PathwayBrowser/#/R-GGA-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Gallus gallus A0A1I7Q426 R-GGA-9679787 https://reactome.org/PathwayBrowser/#/R-GGA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Gallus gallus A0A1I7Q428 R-GGA-6786048 https://reactome.org/PathwayBrowser/#/R-GGA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Gallus gallus A0A1I7Q445 R-GGA-5358510 https://reactome.org/PathwayBrowser/#/R-GGA-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Gallus gallus A0A1I7Q445 R-GGA-5358518 https://reactome.org/PathwayBrowser/#/R-GGA-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Gallus gallus A0A1I7Q445 R-GGA-5358525 https://reactome.org/PathwayBrowser/#/R-GGA-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Gallus gallus A0A1I7Q445 R-GGA-5358597 https://reactome.org/PathwayBrowser/#/R-GGA-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Gallus gallus A0A1I7Q445 R-GGA-5358599 https://reactome.org/PathwayBrowser/#/R-GGA-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Gallus gallus A0A1I7Q445 R-GGA-5358912 https://reactome.org/PathwayBrowser/#/R-GGA-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Gallus gallus A0A1I7Q445 R-GGA-5444516 https://reactome.org/PathwayBrowser/#/R-GGA-5444516 Formation of MSH2:MSH6 Complex IEA Gallus gallus A0A1K0GGH0 R-CFA-1237325 https://reactome.org/PathwayBrowser/#/R-CFA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Canis familiaris A0A1K0GGH0 R-CFA-1247668 https://reactome.org/PathwayBrowser/#/R-CFA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Canis familiaris A0A1K0GGH0 R-CFA-2230938 https://reactome.org/PathwayBrowser/#/R-CFA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Canis familiaris A0A1K0GGH0 R-CFA-6798745 https://reactome.org/PathwayBrowser/#/R-CFA-6798745 Exocytosis of tertiary granule lumen proteins IEA Canis familiaris A0A1K0GGH0 R-CFA-6800434 https://reactome.org/PathwayBrowser/#/R-CFA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Canis familiaris A0A1K0GGH0 R-CFA-6806831 https://reactome.org/PathwayBrowser/#/R-CFA-6806831 CYB5Rs reduce MetHb to HbA IEA Canis familiaris A0A1K0GGH0 R-CFA-9707504 https://reactome.org/PathwayBrowser/#/R-CFA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Canis familiaris A0A1K0GGH0 R-CFA-9707516 https://reactome.org/PathwayBrowser/#/R-CFA-9707516 FeHM dissociates from MetHb IEA Canis familiaris A0A1K0GGH0 R-CFA-9709317 https://reactome.org/PathwayBrowser/#/R-CFA-9709317 CO binds to free ferrohemoglobin IEA Canis familiaris A0A1K0GGH0 R-CFA-9709360 https://reactome.org/PathwayBrowser/#/R-CFA-9709360 H2O2 reduces MetHb IEA Canis familiaris A0A1L1QZL6 R-DRE-9842833 https://reactome.org/PathwayBrowser/#/R-DRE-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Danio rerio A0A1L1RIM9 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1L1RIP9 R-GGA-1247910 https://reactome.org/PathwayBrowser/#/R-GGA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Gallus gallus A0A1L1RIP9 R-GGA-9753632 https://reactome.org/PathwayBrowser/#/R-GGA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Gallus gallus A0A1L1RIQ5 R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus A0A1L1RIQ5 R-GGA-9709406 https://reactome.org/PathwayBrowser/#/R-GGA-9709406 CO binds to Cytochrome c oxidase IEA Gallus gallus A0A1L1RIR0 R-GGA-5689544 https://reactome.org/PathwayBrowser/#/R-GGA-5689544 UCHL5 binds INO80 complex IEA Gallus gallus A0A1L1RIR0 R-GGA-5691006 https://reactome.org/PathwayBrowser/#/R-GGA-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Gallus gallus A0A1L1RIW4 R-GGA-2029468 https://reactome.org/PathwayBrowser/#/R-GGA-2029468 Conversion of PA into DAG by PAP-1 IEA Gallus gallus A0A1L1RIW5 R-GGA-6805546 https://reactome.org/PathwayBrowser/#/R-GGA-6805546 Keratin type I binds keratin type II IEA Gallus gallus A0A1L1RIW5 R-GGA-6805573 https://reactome.org/PathwayBrowser/#/R-GGA-6805573 Keratin type I/type II heterodimers form tetramers IEA Gallus gallus A0A1L1RIW5 R-GGA-6806610 https://reactome.org/PathwayBrowser/#/R-GGA-6806610 Keratin filament formation IEA Gallus gallus A0A1L1RIW5 R-GGA-6806613 https://reactome.org/PathwayBrowser/#/R-GGA-6806613 Keratin tetramers bind to form unit length filaments IEA Gallus gallus A0A1L1RIW5 R-GGA-6806629 https://reactome.org/PathwayBrowser/#/R-GGA-6806629 Formation of tonofilament bundles IEA Gallus gallus A0A1L1RIW5 R-GGA-6809393 https://reactome.org/PathwayBrowser/#/R-GGA-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Gallus gallus A0A1L1RIW5 R-GGA-6810357 https://reactome.org/PathwayBrowser/#/R-GGA-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Gallus gallus A0A1L1RIY5 R-GGA-211186 https://reactome.org/PathwayBrowser/#/R-GGA-211186 Cleavage of DFF45 (224) by caspase-3 IEA Gallus gallus A0A1L1RIY5 R-GGA-211190 https://reactome.org/PathwayBrowser/#/R-GGA-211190 Caspase 3-mediated cleavage of DFF45 (117) IEA Gallus gallus A0A1L1RIY5 R-GGA-211191 https://reactome.org/PathwayBrowser/#/R-GGA-211191 Association of DFF with alpha:beta importin IEA Gallus gallus A0A1L1RIY5 R-GGA-211206 https://reactome.org/PathwayBrowser/#/R-GGA-211206 Translocation of DFF to the nucleus IEA Gallus gallus A0A1L1RIY5 R-GGA-211207 https://reactome.org/PathwayBrowser/#/R-GGA-211207 Cleaved fragments of DFF45 dissociate from DFF40 IEA Gallus gallus A0A1L1RIY5 R-GGA-211224 https://reactome.org/PathwayBrowser/#/R-GGA-211224 Association of DFF40 with DFF45 IEA Gallus gallus A0A1L1RIY5 R-GGA-9029667 https://reactome.org/PathwayBrowser/#/R-GGA-9029667 DFF dissociates from importin-alpha:importin-beta IEA Gallus gallus A0A1L1RIZ2 R-GGA-1482533 https://reactome.org/PathwayBrowser/#/R-GGA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Gallus gallus A0A1L1RIZ2 R-GGA-1482547 https://reactome.org/PathwayBrowser/#/R-GGA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Gallus gallus A0A1L1RJ14 R-GGA-1013012 https://reactome.org/PathwayBrowser/#/R-GGA-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Gallus gallus A0A1L1RJ14 R-GGA-1013013 https://reactome.org/PathwayBrowser/#/R-GGA-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Gallus gallus A0A1L1RJ14 R-GGA-1013020 https://reactome.org/PathwayBrowser/#/R-GGA-1013020 Activation of GIRK/Kir3 Channels IEA Gallus gallus A0A1L1RJ14 R-GGA-112271 https://reactome.org/PathwayBrowser/#/R-GGA-112271 The receptor:G-protein complex dissociates IEA Gallus gallus A0A1L1RJ14 R-GGA-114552 https://reactome.org/PathwayBrowser/#/R-GGA-114552 Thrombin-activated PARs activate G12/13 IEA Gallus gallus A0A1L1RJ14 R-GGA-114558 https://reactome.org/PathwayBrowser/#/R-GGA-114558 Thrombin-activated PARs activate Gq IEA Gallus gallus A0A1L1RJ14 R-GGA-167408 https://reactome.org/PathwayBrowser/#/R-GGA-167408 The high affinity receptor complex binds to G-protein IEA Gallus gallus A0A1L1RJ14 R-GGA-167419 https://reactome.org/PathwayBrowser/#/R-GGA-167419 The receptor:G-protein complex releases GDP IEA Gallus gallus A0A1L1RJ14 R-GGA-167429 https://reactome.org/PathwayBrowser/#/R-GGA-167429 The receptor:G-protein complex binds GTP IEA Gallus gallus A0A1L1RJ14 R-GGA-167433 https://reactome.org/PathwayBrowser/#/R-GGA-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Gallus gallus A0A1L1RJ14 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus A0A1L1RJ14 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1L1RJ14 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1L1RJ14 R-GGA-392195 https://reactome.org/PathwayBrowser/#/R-GGA-392195 Gi activation by P2Y purinoceptor 12 IEA Gallus gallus A0A1L1RJ14 R-GGA-392295 https://reactome.org/PathwayBrowser/#/R-GGA-392295 Gbeta:gamma recruits PI3K gamma IEA Gallus gallus A0A1L1RJ14 R-GGA-392300 https://reactome.org/PathwayBrowser/#/R-GGA-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Gallus gallus A0A1L1RJ14 R-GGA-3965444 https://reactome.org/PathwayBrowser/#/R-GGA-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Gallus gallus A0A1L1RJ14 R-GGA-3965447 https://reactome.org/PathwayBrowser/#/R-GGA-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Gallus gallus A0A1L1RJ14 R-GGA-396996 https://reactome.org/PathwayBrowser/#/R-GGA-396996 Thrombin-activated PARs binds G-protein Gq IEA Gallus gallus A0A1L1RJ14 R-GGA-397835 https://reactome.org/PathwayBrowser/#/R-GGA-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Gallus gallus A0A1L1RJ14 R-GGA-397891 https://reactome.org/PathwayBrowser/#/R-GGA-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Gallus gallus A0A1L1RJ14 R-GGA-398040 https://reactome.org/PathwayBrowser/#/R-GGA-398040 Gbeta:gamma activation of PLC beta IEA Gallus gallus A0A1L1RJ14 R-GGA-398193 https://reactome.org/PathwayBrowser/#/R-GGA-398193 PLC beta-mediated PIP2 hydrolysis IEA Gallus gallus A0A1L1RJ14 R-GGA-418576 https://reactome.org/PathwayBrowser/#/R-GGA-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Gallus gallus A0A1L1RJ14 R-GGA-420883 https://reactome.org/PathwayBrowser/#/R-GGA-420883 Opsins act as GEFs for G alpha-t IEA Gallus gallus A0A1L1RJ14 R-GGA-428749 https://reactome.org/PathwayBrowser/#/R-GGA-428749 Activated TP receptor binds G-proten Gq IEA Gallus gallus A0A1L1RJ14 R-GGA-428750 https://reactome.org/PathwayBrowser/#/R-GGA-428750 Gq activation by TP receptor IEA Gallus gallus A0A1L1RJ14 R-GGA-428752 https://reactome.org/PathwayBrowser/#/R-GGA-428752 Dissociation of the TP:Gq complex IEA Gallus gallus A0A1L1RJ14 R-GGA-428909 https://reactome.org/PathwayBrowser/#/R-GGA-428909 Activated TP receptor binds G-protein G13 IEA Gallus gallus A0A1L1RJ14 R-GGA-428917 https://reactome.org/PathwayBrowser/#/R-GGA-428917 G13 activation by TP receptor IEA Gallus gallus A0A1L1RJ14 R-GGA-428918 https://reactome.org/PathwayBrowser/#/R-GGA-428918 Dissociation of the TP:G13 complex IEA Gallus gallus A0A1L1RJ14 R-GGA-500717 https://reactome.org/PathwayBrowser/#/R-GGA-500717 Activation of GRIK3 homomer IEA Gallus gallus A0A1L1RJ14 R-GGA-6814418 https://reactome.org/PathwayBrowser/#/R-GGA-6814418 PDCL promotes formation of G-beta:G-gamma heterodimers IEA Gallus gallus A0A1L1RJ14 R-GGA-749446 https://reactome.org/PathwayBrowser/#/R-GGA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Gallus gallus A0A1L1RJ14 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1L1RJ14 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1L1RJ14 R-GGA-749453 https://reactome.org/PathwayBrowser/#/R-GGA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Gallus gallus A0A1L1RJ14 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1L1RJ14 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1L1RJ14 R-GGA-750988 https://reactome.org/PathwayBrowser/#/R-GGA-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Gallus gallus A0A1L1RJ14 R-GGA-750993 https://reactome.org/PathwayBrowser/#/R-GGA-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Gallus gallus A0A1L1RJ14 R-GGA-751001 https://reactome.org/PathwayBrowser/#/R-GGA-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Gallus gallus A0A1L1RJ14 R-GGA-751019 https://reactome.org/PathwayBrowser/#/R-GGA-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Gallus gallus A0A1L1RJ14 R-GGA-751024 https://reactome.org/PathwayBrowser/#/R-GGA-751024 The Ligand:GPCR:Gz complex dissociates IEA Gallus gallus A0A1L1RJ14 R-GGA-751027 https://reactome.org/PathwayBrowser/#/R-GGA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Gallus gallus A0A1L1RJ14 R-GGA-751029 https://reactome.org/PathwayBrowser/#/R-GGA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Gallus gallus A0A1L1RJ14 R-GGA-751039 https://reactome.org/PathwayBrowser/#/R-GGA-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Gallus gallus A0A1L1RJ14 R-GGA-8850560 https://reactome.org/PathwayBrowser/#/R-GGA-8850560 G-protein alpha releases G-protein heterotrimer from PDCL IEA Gallus gallus A0A1L1RJ14 R-GGA-8964241 https://reactome.org/PathwayBrowser/#/R-GGA-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Gallus gallus A0A1L1RJ14 R-GGA-8964271 https://reactome.org/PathwayBrowser/#/R-GGA-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Gallus gallus A0A1L1RJ14 R-GGA-8964317 https://reactome.org/PathwayBrowser/#/R-GGA-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Gallus gallus A0A1L1RJ14 R-GGA-8964599 https://reactome.org/PathwayBrowser/#/R-GGA-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Gallus gallus A0A1L1RJ14 R-GGA-8964604 https://reactome.org/PathwayBrowser/#/R-GGA-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Gallus gallus A0A1L1RJ14 R-GGA-8964605 https://reactome.org/PathwayBrowser/#/R-GGA-8964605 PAK1:ARHGEF6 complex binds G-protein beta-gamma complex IEA Gallus gallus A0A1L1RJ14 R-GGA-8964614 https://reactome.org/PathwayBrowser/#/R-GGA-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Gallus gallus A0A1L1RJ14 R-GGA-8964634 https://reactome.org/PathwayBrowser/#/R-GGA-8964634 CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex IEA Gallus gallus A0A1L1RJ14 R-GGA-8982637 https://reactome.org/PathwayBrowser/#/R-GGA-8982637 Opsins binds G alpha-t IEA Gallus gallus A0A1L1RJ14 R-GGA-8982640 https://reactome.org/PathwayBrowser/#/R-GGA-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Gallus gallus A0A1L1RJ14 R-GGA-9021596 https://reactome.org/PathwayBrowser/#/R-GGA-9021596 Membrane estrogen receptors bind SRC IEA Gallus gallus A0A1L1RJ14 R-GGA-9021600 https://reactome.org/PathwayBrowser/#/R-GGA-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Gallus gallus A0A1L1RJ14 R-GGA-9021601 https://reactome.org/PathwayBrowser/#/R-GGA-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Gallus gallus A0A1L1RJ14 R-GGA-9036301 https://reactome.org/PathwayBrowser/#/R-GGA-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Gallus gallus A0A1L1RJ14 R-GGA-9036307 https://reactome.org/PathwayBrowser/#/R-GGA-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Gallus gallus A0A1L1RJ24 R-GGA-914012 https://reactome.org/PathwayBrowser/#/R-GGA-914012 GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins IEA Gallus gallus A0A1L1RJ24 R-GGA-914018 https://reactome.org/PathwayBrowser/#/R-GGA-914018 Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein IEA Gallus gallus A0A1L1RJ75 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1L1RJ75 R-GGA-9842833 https://reactome.org/PathwayBrowser/#/R-GGA-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Gallus gallus A0A1L1RJ75 R-GGA-9842835 https://reactome.org/PathwayBrowser/#/R-GGA-9842835 KRAB-ZFP binds retroelement DNA in chromatin IEA Gallus gallus A0A1L1RJ75 R-GGA-9842839 https://reactome.org/PathwayBrowser/#/R-GGA-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1L1RJ75 R-GGA-9843978 https://reactome.org/PathwayBrowser/#/R-GGA-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1L1RJ78 R-GGA-4086059 https://reactome.org/PathwayBrowser/#/R-GGA-4086059 SUMOylation of NPM1 with SUMO2,3 IEA Gallus gallus A0A1L1RJ78 R-GGA-4086088 https://reactome.org/PathwayBrowser/#/R-GGA-4086088 SUMOylation of NPM1 with SUMO1 IEA Gallus gallus A0A1L1RJ78 R-GGA-606287 https://reactome.org/PathwayBrowser/#/R-GGA-606287 RSF complex binds the centromere IEA Gallus gallus A0A1L1RJ78 R-GGA-606289 https://reactome.org/PathwayBrowser/#/R-GGA-606289 New CENPA-containing nucleosomes are deposited at the centromere IEA Gallus gallus A0A1L1RJ78 R-GGA-606326 https://reactome.org/PathwayBrowser/#/R-GGA-606326 HJURP:CENPA complex localizes to the centromere IEA Gallus gallus A0A1L1RJ78 R-GGA-6801675 https://reactome.org/PathwayBrowser/#/R-GGA-6801675 PLK2 phosphorylates NPM1 IEA Gallus gallus A0A1L1RJ78 R-GGA-8869568 https://reactome.org/PathwayBrowser/#/R-GGA-8869568 NPM1 binds TFAP2A homodimer IEA Gallus gallus A0A1L1RJ78 R-GGA-9835328 https://reactome.org/PathwayBrowser/#/R-GGA-9835328 NPM binds PKR IEA Gallus gallus A0A1L1RJB0 R-GGA-6785762 https://reactome.org/PathwayBrowser/#/R-GGA-6785762 IL13RA1 binds TYK2 IEA Gallus gallus A0A1L1RJB0 R-GGA-6785821 https://reactome.org/PathwayBrowser/#/R-GGA-6785821 SOCS5,(SOCS1) bind IL4RA IEA Gallus gallus A0A1L1RJB0 R-GGA-6786050 https://reactome.org/PathwayBrowser/#/R-GGA-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated IEA Gallus gallus A0A1L1RJB0 R-GGA-6786070 https://reactome.org/PathwayBrowser/#/R-GGA-6786070 IL4:IL4R:JAK2 binds IL13RA1:TYK2 IEA Gallus gallus A0A1L1RJB0 R-GGA-6786110 https://reactome.org/PathwayBrowser/#/R-GGA-6786110 JAK1 binds IL4R in IL13-bound IL13R type II IEA Gallus gallus A0A1L1RJB0 R-GGA-6788571 https://reactome.org/PathwayBrowser/#/R-GGA-6788571 STAT1,STAT3,STAT6 bind IL13:IL13R type II IEA Gallus gallus A0A1L1RJB0 R-GGA-6788582 https://reactome.org/PathwayBrowser/#/R-GGA-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Gallus gallus A0A1L1RJB0 R-GGA-6788628 https://reactome.org/PathwayBrowser/#/R-GGA-6788628 p-Y-STATs dissociate IEA Gallus gallus A0A1L1RJC1 R-GGA-6784628 https://reactome.org/PathwayBrowser/#/R-GGA-6784628 PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Gallus gallus A0A1L1RJC1 R-GGA-6784676 https://reactome.org/PathwayBrowser/#/R-GGA-6784676 PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer IEA Gallus gallus A0A1L1RJC1 R-GGA-8857928 https://reactome.org/PathwayBrowser/#/R-GGA-8857928 GPIHBP1 binds HSPG:LPL dimer IEA Gallus gallus A0A1L1RJC1 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus A0A1L1RJC9 R-GGA-8954327 https://reactome.org/PathwayBrowser/#/R-GGA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Gallus gallus A0A1L1RJF6 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1L1RJG1 R-GGA-110133 https://reactome.org/PathwayBrowser/#/R-GGA-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Gallus gallus A0A1L1RJG1 R-GGA-73788 https://reactome.org/PathwayBrowser/#/R-GGA-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Gallus gallus A0A1L1RJG1 R-GGA-9748949 https://reactome.org/PathwayBrowser/#/R-GGA-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Gallus gallus A0A1L1RJG1 R-GGA-9748963 https://reactome.org/PathwayBrowser/#/R-GGA-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Gallus gallus A0A1L1RJI1 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus A0A1L1RJI1 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus A0A1L1RJI1 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus A0A1L1RJI1 R-GGA-5694417 https://reactome.org/PathwayBrowser/#/R-GGA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Gallus gallus A0A1L1RJI1 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus A0A1L1RJI1 R-GGA-5694445 https://reactome.org/PathwayBrowser/#/R-GGA-5694445 CNIH1 binds TFGA and AREG precursors IEA Gallus gallus A0A1L1RJI1 R-GGA-5694446 https://reactome.org/PathwayBrowser/#/R-GGA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Gallus gallus A0A1L1RJI1 R-GGA-5694522 https://reactome.org/PathwayBrowser/#/R-GGA-5694522 Inner coat assembly and cargo binding IEA Gallus gallus A0A1L1RJI1 R-GGA-5694527 https://reactome.org/PathwayBrowser/#/R-GGA-5694527 Loss of SAR1B GTPase IEA Gallus gallus A0A1L1RJI2 R-GGA-8852129 https://reactome.org/PathwayBrowser/#/R-GGA-8852129 UBA1 conjugates ubiquitin to cytosolic E2 enzymes IEA Gallus gallus A0A1L1RJI2 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1L1RJI2 R-GGA-983152 https://reactome.org/PathwayBrowser/#/R-GGA-983152 Transfer of ubiquitin from E1 to E2 IEA Gallus gallus A0A1L1RJI2 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1L1RJI2 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1L1RJL0 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus A0A1L1RJP8 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1L1RJP8 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1L1RJP8 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1L1RJP8 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1L1RJP8 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1L1RJP8 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus A0A1L1RJP8 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1L1RJP8 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1L1RJP8 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1L1RJP8 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1L1RJP8 R-GGA-8849350 https://reactome.org/PathwayBrowser/#/R-GGA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Gallus gallus A0A1L1RJP8 R-GGA-8849353 https://reactome.org/PathwayBrowser/#/R-GGA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Gallus gallus A0A1L1RJP8 R-GGA-9646679 https://reactome.org/PathwayBrowser/#/R-GGA-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Gallus gallus A0A1L1RJP8 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1L1RJP8 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus A0A1L1RJR6 R-GGA-72095 https://reactome.org/PathwayBrowser/#/R-GGA-72095 Internal Methylation of mRNA IEA Gallus gallus A0A1L1RJY0 R-GGA-8854222 https://reactome.org/PathwayBrowser/#/R-GGA-8854222 TBC1D3 associates with RAB5 IEA Gallus gallus A0A1L1RK07 R-GGA-5686924 https://reactome.org/PathwayBrowser/#/R-GGA-5686924 DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs IEA Gallus gallus A0A1L1RK07 R-GGA-5687183 https://reactome.org/PathwayBrowser/#/R-GGA-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Gallus gallus A0A1L1RK07 R-GGA-5687360 https://reactome.org/PathwayBrowser/#/R-GGA-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Gallus gallus A0A1L1RK07 R-GGA-5693533 https://reactome.org/PathwayBrowser/#/R-GGA-5693533 DCLRE1C (ARTEMIS) processes DNA DSB ends IEA Gallus gallus A0A1L1RK07 R-GGA-5693574 https://reactome.org/PathwayBrowser/#/R-GGA-5693574 XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ IEA Gallus gallus A0A1L1RK07 R-GGA-5693575 https://reactome.org/PathwayBrowser/#/R-GGA-5693575 DNA-PKcs autophosphorylates IEA Gallus gallus A0A1L1RK07 R-GGA-5693578 https://reactome.org/PathwayBrowser/#/R-GGA-5693578 TDP1 and TDP2 process unligatable DSB ends IEA Gallus gallus A0A1L1RK07 R-GGA-5693615 https://reactome.org/PathwayBrowser/#/R-GGA-5693615 Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis IEA Gallus gallus A0A1L1RK07 R-GGA-8938770 https://reactome.org/PathwayBrowser/#/R-GGA-8938770 RNF144A binds PRKDC and Ubiquitin:UBE2L3 IEA Gallus gallus A0A1L1RK07 R-GGA-8938773 https://reactome.org/PathwayBrowser/#/R-GGA-8938773 RNF144A polyubiquitinates PRKDC IEA Gallus gallus A0A1L1RK38 R-GGA-1112666 https://reactome.org/PathwayBrowser/#/R-GGA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Gallus gallus A0A1L1RK38 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus A0A1L1RK38 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus A0A1L1RK38 R-GGA-173626 https://reactome.org/PathwayBrowser/#/R-GGA-173626 Activation of C1r IEA Gallus gallus A0A1L1RK38 R-GGA-173631 https://reactome.org/PathwayBrowser/#/R-GGA-173631 Activation of C1s IEA Gallus gallus A0A1L1RK38 R-GGA-1861621 https://reactome.org/PathwayBrowser/#/R-GGA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Gallus gallus A0A1L1RK38 R-GGA-199161 https://reactome.org/PathwayBrowser/#/R-GGA-199161 Fc gamma receptors interact with antigen-bound IgG IEA Gallus gallus A0A1L1RK38 R-GGA-2029268 https://reactome.org/PathwayBrowser/#/R-GGA-2029268 Phosphorylation and activation of PLCG IEA Gallus gallus A0A1L1RK38 R-GGA-2029270 https://reactome.org/PathwayBrowser/#/R-GGA-2029270 Recruitment of PLCgamma to membrane IEA Gallus gallus A0A1L1RK38 R-GGA-2029271 https://reactome.org/PathwayBrowser/#/R-GGA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1L1RK38 R-GGA-2029272 https://reactome.org/PathwayBrowser/#/R-GGA-2029272 Release of PLCG from FCGR IEA Gallus gallus A0A1L1RK38 R-GGA-2029273 https://reactome.org/PathwayBrowser/#/R-GGA-2029273 PI3K binds to p-6Y-SYK IEA Gallus gallus A0A1L1RK38 R-GGA-2029451 https://reactome.org/PathwayBrowser/#/R-GGA-2029451 Activation of RAC1 by VAV IEA Gallus gallus A0A1L1RK38 R-GGA-2029452 https://reactome.org/PathwayBrowser/#/R-GGA-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Gallus gallus A0A1L1RK38 R-GGA-2029453 https://reactome.org/PathwayBrowser/#/R-GGA-2029453 Phosphorylation of VAV IEA Gallus gallus A0A1L1RK38 R-GGA-2029455 https://reactome.org/PathwayBrowser/#/R-GGA-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Gallus gallus A0A1L1RK38 R-GGA-2029457 https://reactome.org/PathwayBrowser/#/R-GGA-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Gallus gallus A0A1L1RK38 R-GGA-2029458 https://reactome.org/PathwayBrowser/#/R-GGA-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Gallus gallus A0A1L1RK38 R-GGA-2029459 https://reactome.org/PathwayBrowser/#/R-GGA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Gallus gallus A0A1L1RK38 R-GGA-2029467 https://reactome.org/PathwayBrowser/#/R-GGA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Gallus gallus A0A1L1RK38 R-GGA-2029476 https://reactome.org/PathwayBrowser/#/R-GGA-2029476 Role of myosins in phagosome formation IEA Gallus gallus A0A1L1RK38 R-GGA-2197697 https://reactome.org/PathwayBrowser/#/R-GGA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Gallus gallus A0A1L1RK38 R-GGA-2203516 https://reactome.org/PathwayBrowser/#/R-GGA-2203516 Alpha-1-Microglobulin is cleaved IEA Gallus gallus A0A1L1RK38 R-GGA-8852266 https://reactome.org/PathwayBrowser/#/R-GGA-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Gallus gallus A0A1L1RK38 R-GGA-8852481 https://reactome.org/PathwayBrowser/#/R-GGA-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Gallus gallus A0A1L1RK38 R-GGA-8858428 https://reactome.org/PathwayBrowser/#/R-GGA-8858428 FCAMR binds IgA IEA Gallus gallus A0A1L1RK38 R-GGA-9021306 https://reactome.org/PathwayBrowser/#/R-GGA-9021306 C1-Inh binds and inactivates C1r, C1s IEA Gallus gallus A0A1L1RK38 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus A0A1L1RK38 R-GGA-9724685 https://reactome.org/PathwayBrowser/#/R-GGA-9724685 IgE binds omalizumab IEA Gallus gallus A0A1L1RK38 R-GGA-983696 https://reactome.org/PathwayBrowser/#/R-GGA-983696 The Immunoglobulin of the BCR binds antigen IEA Gallus gallus A0A1L1RK38 R-GGA-983700 https://reactome.org/PathwayBrowser/#/R-GGA-983700 SYK binds the activated BCR IEA Gallus gallus A0A1L1RK38 R-GGA-983703 https://reactome.org/PathwayBrowser/#/R-GGA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Gallus gallus A0A1L1RK38 R-GGA-983707 https://reactome.org/PathwayBrowser/#/R-GGA-983707 SYK autophosphorylates at the activated BCR IEA Gallus gallus A0A1L1RK45 R-GGA-425483 https://reactome.org/PathwayBrowser/#/R-GGA-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Gallus gallus A0A1L1RK46 R-GGA-8852013 https://reactome.org/PathwayBrowser/#/R-GGA-8852013 BTNL8 binds resting T cell surface IEA Gallus gallus A0A1L1RK48 R-GGA-6791222 https://reactome.org/PathwayBrowser/#/R-GGA-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Gallus gallus A0A1L1RK48 R-GGA-6791227 https://reactome.org/PathwayBrowser/#/R-GGA-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Gallus gallus A0A1L1RK55 R-GGA-5638004 https://reactome.org/PathwayBrowser/#/R-GGA-5638004 RP2 binds ARL3:GTP:UNC119B IEA Gallus gallus A0A1L1RK55 R-GGA-5638006 https://reactome.org/PathwayBrowser/#/R-GGA-5638006 ARL3 hydrolyzes GTP IEA Gallus gallus A0A1L1RK55 R-GGA-5638007 https://reactome.org/PathwayBrowser/#/R-GGA-5638007 RP2 activates the GTPase activity of ARL3 IEA Gallus gallus A0A1L1RK55 R-GGA-5638016 https://reactome.org/PathwayBrowser/#/R-GGA-5638016 RP2:ARL3:GDP:UNC119B dissociates IEA Gallus gallus A0A1L1RK70 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1L1RKA6 R-GGA-5696872 https://reactome.org/PathwayBrowser/#/R-GGA-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Gallus gallus A0A1L1RKA6 R-GGA-9824888 https://reactome.org/PathwayBrowser/#/R-GGA-9824888 OPTN, TBK1 bind ubiquitinated MOM proteins IEA Gallus gallus A0A1L1RKA6 R-GGA-9824892 https://reactome.org/PathwayBrowser/#/R-GGA-9824892 MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria IEA Gallus gallus A0A1L1RKA6 R-GGA-9824894 https://reactome.org/PathwayBrowser/#/R-GGA-9824894 TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins IEA Gallus gallus A0A1L1RKA6 R-GGA-9824897 https://reactome.org/PathwayBrowser/#/R-GGA-9824897 p-S-TBK1 phosphorylates OPTN IEA Gallus gallus A0A1L1RKA6 R-GGA-9835009 https://reactome.org/PathwayBrowser/#/R-GGA-9835009 PRKN binds p-S-Ub:MOM proteins IEA Gallus gallus A0A1L1RKA6 R-GGA-9840807 https://reactome.org/PathwayBrowser/#/R-GGA-9840807 OPTN binds ATG9A IEA Gallus gallus A0A1L1RKB7 R-GGA-418365 https://reactome.org/PathwayBrowser/#/R-GGA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Gallus gallus A0A1L1RKB7 R-GGA-427910 https://reactome.org/PathwayBrowser/#/R-GGA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Gallus gallus A0A1L1RKF5 R-GGA-196126 https://reactome.org/PathwayBrowser/#/R-GGA-196126 CHOL translocates from cytosol to mitochondrial intermembrane space IEA Gallus gallus A0A1L1RKG9 R-GGA-5358494 https://reactome.org/PathwayBrowser/#/R-GGA-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Gallus gallus A0A1L1RKJ5 R-GGA-2130706 https://reactome.org/PathwayBrowser/#/R-GGA-2130706 MHC class II antigen processing IEA Gallus gallus A0A1L1RKJ5 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1L1RKJ5 R-GGA-9638120 https://reactome.org/PathwayBrowser/#/R-GGA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Gallus gallus A0A1L1RKT0 R-GGA-141367 https://reactome.org/PathwayBrowser/#/R-GGA-141367 Myristoylation of tBID by NMT1 IEA Gallus gallus A0A1L1RKY9 R-GGA-445699 https://reactome.org/PathwayBrowser/#/R-GGA-445699 ATP Hydrolysis By Myosin IEA Gallus gallus A0A1L1RKY9 R-GGA-445700 https://reactome.org/PathwayBrowser/#/R-GGA-445700 Myosin Binds ATP IEA Gallus gallus A0A1L1RKY9 R-GGA-445704 https://reactome.org/PathwayBrowser/#/R-GGA-445704 Calcium Binds Caldesmon IEA Gallus gallus A0A1L1RKY9 R-GGA-445705 https://reactome.org/PathwayBrowser/#/R-GGA-445705 Release Of ADP From Myosin IEA Gallus gallus A0A1L1RKZ8 R-GGA-3108212 https://reactome.org/PathwayBrowser/#/R-GGA-3108212 SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 IEA Gallus gallus A0A1L1RKZ9 R-GGA-6811431 https://reactome.org/PathwayBrowser/#/R-GGA-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Gallus gallus A0A1L1RKZ9 R-GGA-6811433 https://reactome.org/PathwayBrowser/#/R-GGA-6811433 The COG tethering complex interacts with numerous SNAREs at the Golgi membrane IEA Gallus gallus A0A1L1RKZ9 R-GGA-6814671 https://reactome.org/PathwayBrowser/#/R-GGA-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Gallus gallus A0A1L1RKZ9 R-GGA-6814676 https://reactome.org/PathwayBrowser/#/R-GGA-6814676 SNAPs and NSF hexamer bind cis-SNARE at the TGN IEA Gallus gallus A0A1L1RKZ9 R-GGA-6814682 https://reactome.org/PathwayBrowser/#/R-GGA-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Gallus gallus A0A1L1RKZ9 R-GGA-6814683 https://reactome.org/PathwayBrowser/#/R-GGA-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN IEA Gallus gallus A0A1L1RKZ9 R-GGA-6814684 https://reactome.org/PathwayBrowser/#/R-GGA-6814684 cis-SNARE binds SNAPs and NSF hexamer at the TGN IEA Gallus gallus A0A1L1RL31 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1L1RL50 R-GGA-9013004 https://reactome.org/PathwayBrowser/#/R-GGA-9013004 RHOA binds effectors at the ER membrane IEA Gallus gallus A0A1L1RL76 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1L1RL76 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1L1RL76 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1L1RL76 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1L1RL76 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1L1RL76 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1L1RL76 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1L1RL84 R-GGA-6809393 https://reactome.org/PathwayBrowser/#/R-GGA-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Gallus gallus A0A1L1RL84 R-GGA-6810357 https://reactome.org/PathwayBrowser/#/R-GGA-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Gallus gallus A0A1L1RL84 R-GGA-6814695 https://reactome.org/PathwayBrowser/#/R-GGA-6814695 PERP binds desmosomes IEA Gallus gallus A0A1L1RL84 R-GGA-9696266 https://reactome.org/PathwayBrowser/#/R-GGA-9696266 RND2 binds effectors IEA Gallus gallus A0A1L1RL84 R-GGA-9696268 https://reactome.org/PathwayBrowser/#/R-GGA-9696268 RND3 binds effectors IEA Gallus gallus A0A1L1RL84 R-GGA-9696271 https://reactome.org/PathwayBrowser/#/R-GGA-9696271 RND1 binds effectors IEA Gallus gallus A0A1L1RL86 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1L1RLD5 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1L1RLH2 R-GGA-177934 https://reactome.org/PathwayBrowser/#/R-GGA-177934 EGFR autophosphorylation IEA Gallus gallus A0A1L1RLH2 R-GGA-9851407 https://reactome.org/PathwayBrowser/#/R-GGA-9851407 FAM83B, (FAM83A, FAM83D) bind EGFR IEA Gallus gallus A0A1L1RLI4 R-GGA-8852013 https://reactome.org/PathwayBrowser/#/R-GGA-8852013 BTNL8 binds resting T cell surface IEA Gallus gallus A0A1L1RLK3 R-GGA-5685319 https://reactome.org/PathwayBrowser/#/R-GGA-5685319 CX3 complex formation IEA Gallus gallus A0A1L1RLK3 R-GGA-5685838 https://reactome.org/PathwayBrowser/#/R-GGA-5685838 CX3 complex binds D-loop structures IEA Gallus gallus A0A1L1RLK3 R-GGA-5693539 https://reactome.org/PathwayBrowser/#/R-GGA-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Gallus gallus A0A1L1RLK3 R-GGA-5693584 https://reactome.org/PathwayBrowser/#/R-GGA-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Gallus gallus A0A1L1RLK3 R-GGA-5693593 https://reactome.org/PathwayBrowser/#/R-GGA-5693593 D-loop extension by DNA polymerases IEA Gallus gallus A0A1L1RLK3 R-GGA-9853389 https://reactome.org/PathwayBrowser/#/R-GGA-9853389 FIGNL1 binds RAD51 IEA Gallus gallus A0A1L1RLL0 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1L1RLL0 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1L1RLL0 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1L1RLL0 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1L1RLL0 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1L1RLL0 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1L1RLL0 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1L1RLN5 R-GGA-8866542 https://reactome.org/PathwayBrowser/#/R-GGA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Gallus gallus A0A1L1RLN5 R-GGA-8866546 https://reactome.org/PathwayBrowser/#/R-GGA-8866546 RNF5 and RNF185 ubiquitinate misfolded CFTR IEA Gallus gallus A0A1L1RLN5 R-GGA-8866551 https://reactome.org/PathwayBrowser/#/R-GGA-8866551 CFTR binds components of the ERAD machinery for ubiquitination and degradation IEA Gallus gallus A0A1L1RLP5 R-GGA-8850529 https://reactome.org/PathwayBrowser/#/R-GGA-8850529 RGS proteins bind GNB5 and CCT/TRiC IEA Gallus gallus A0A1L1RLP5 R-GGA-8850539 https://reactome.org/PathwayBrowser/#/R-GGA-8850539 Release of GNB5:RGS dimers from CCT/TRiC IEA Gallus gallus A0A1L1RLP5 R-GGA-8982012 https://reactome.org/PathwayBrowser/#/R-GGA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Gallus gallus A0A1L1RLP5 R-GGA-8982019 https://reactome.org/PathwayBrowser/#/R-GGA-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Gallus gallus A0A1L1RLP5 R-GGA-8982020 https://reactome.org/PathwayBrowser/#/R-GGA-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Gallus gallus A0A1L1RLR2 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1L1RLR2 R-GGA-9668389 https://reactome.org/PathwayBrowser/#/R-GGA-9668389 VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations IEA Gallus gallus A0A1L1RLR2 R-GGA-9668395 https://reactome.org/PathwayBrowser/#/R-GGA-9668395 CHMP7 binds CC2D1B IEA Gallus gallus A0A1L1RLR2 R-GGA-9668405 https://reactome.org/PathwayBrowser/#/R-GGA-9668405 SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin IEA Gallus gallus A0A1L1RLR7 R-GGA-9817397 https://reactome.org/PathwayBrowser/#/R-GGA-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Gallus gallus A0A1L1RLU6 R-GGA-212380 https://reactome.org/PathwayBrowser/#/R-GGA-212380 Formation of TRAP coactivator complex IEA Gallus gallus A0A1L1RLU6 R-GGA-212432 https://reactome.org/PathwayBrowser/#/R-GGA-212432 Formation of DRIP coactivator complex IEA Gallus gallus A0A1L1RLU6 R-GGA-9843120 https://reactome.org/PathwayBrowser/#/R-GGA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1L1RLV7 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A1L1RLV7 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A1L1RLV7 R-GGA-141423 https://reactome.org/PathwayBrowser/#/R-GGA-141423 Binding of the MCC complex to the APC/C complex IEA Gallus gallus A0A1L1RLV7 R-GGA-141429 https://reactome.org/PathwayBrowser/#/R-GGA-141429 Inactivation of APC/C via CDC20 sequestration IEA Gallus gallus A0A1L1RLV7 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A1L1RLV7 R-GGA-141437 https://reactome.org/PathwayBrowser/#/R-GGA-141437 Formation of the MCC complex IEA Gallus gallus A0A1L1RLV7 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A1L1RLV7 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1L1RLV7 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1L1RLV7 R-GGA-174104 https://reactome.org/PathwayBrowser/#/R-GGA-174104 Ubiquitination of Cyclin A by APC/C:Cdc20 complex IEA Gallus gallus A0A1L1RLV7 R-GGA-174171 https://reactome.org/PathwayBrowser/#/R-GGA-174171 Association of Cyclin A with the APC/C IEA Gallus gallus A0A1L1RLV7 R-GGA-174238 https://reactome.org/PathwayBrowser/#/R-GGA-174238 Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 IEA Gallus gallus A0A1L1RLV7 R-GGA-174255 https://reactome.org/PathwayBrowser/#/R-GGA-174255 Degradation multiubiquitinated Cyclin A IEA Gallus gallus A0A1L1RLV7 R-GGA-179410 https://reactome.org/PathwayBrowser/#/R-GGA-179410 Association of Nek2A with MCC:APC/C IEA Gallus gallus A0A1L1RLV7 R-GGA-179417 https://reactome.org/PathwayBrowser/#/R-GGA-179417 Multiubiquitination of Nek2A IEA Gallus gallus A0A1L1RLV7 R-GGA-179421 https://reactome.org/PathwayBrowser/#/R-GGA-179421 Degradation of multiubiquitinated Nek2A IEA Gallus gallus A0A1L1RLV7 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1L1RLV7 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1L1RLV7 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1L1RLV7 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A1L1RLV7 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1L1RLW1 R-GGA-2574840 https://reactome.org/PathwayBrowser/#/R-GGA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Gallus gallus A0A1L1RLW1 R-GGA-2574845 https://reactome.org/PathwayBrowser/#/R-GGA-2574845 AJUBA binds centrosome-associated AURKA IEA Gallus gallus A0A1L1RLW1 R-GGA-3000310 https://reactome.org/PathwayBrowser/#/R-GGA-3000310 AURKA phosphorylates PLK1 IEA Gallus gallus A0A1L1RLW1 R-GGA-3000319 https://reactome.org/PathwayBrowser/#/R-GGA-3000319 BORA binds PLK1 and AURKA IEA Gallus gallus A0A1L1RLW1 R-GGA-380272 https://reactome.org/PathwayBrowser/#/R-GGA-380272 Plk1-mediated phosphorylation of Nlp IEA Gallus gallus A0A1L1RLW1 R-GGA-380283 https://reactome.org/PathwayBrowser/#/R-GGA-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Gallus gallus A0A1L1RLW1 R-GGA-380294 https://reactome.org/PathwayBrowser/#/R-GGA-380294 Loss of C-Nap-1 from centrosomes IEA Gallus gallus A0A1L1RLW1 R-GGA-380311 https://reactome.org/PathwayBrowser/#/R-GGA-380311 Recruitment of Plk1 to centrosomes IEA Gallus gallus A0A1L1RLW1 R-GGA-380455 https://reactome.org/PathwayBrowser/#/R-GGA-380455 Recruitment of CDK11p58 to the centrosomes IEA Gallus gallus A0A1L1RLW1 R-GGA-380508 https://reactome.org/PathwayBrowser/#/R-GGA-380508 Translocation of NuMA to the centrosomes IEA Gallus gallus A0A1L1RLW1 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1L1RLW1 R-GGA-5626228 https://reactome.org/PathwayBrowser/#/R-GGA-5626228 The distal appendage proteins recruit TTBK2 IEA Gallus gallus A0A1L1RLW1 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1L1RLW1 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1L1RLW1 R-GGA-8853405 https://reactome.org/PathwayBrowser/#/R-GGA-8853405 TPX2 binds AURKA at centrosomes IEA Gallus gallus A0A1L1RLW1 R-GGA-8853419 https://reactome.org/PathwayBrowser/#/R-GGA-8853419 TPX2 promotes AURKA autophosphorylation IEA Gallus gallus A0A1L1RM00 R-GGA-110307 https://reactome.org/PathwayBrowser/#/R-GGA-110307 REV1 binds AP-dsDNA IEA Gallus gallus A0A1L1RM00 R-GGA-110308 https://reactome.org/PathwayBrowser/#/R-GGA-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Gallus gallus A0A1L1RM00 R-GGA-110311 https://reactome.org/PathwayBrowser/#/R-GGA-110311 POLZ extends translesion synthesis IEA Gallus gallus A0A1L1RM00 R-GGA-110316 https://reactome.org/PathwayBrowser/#/R-GGA-110316 POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template IEA Gallus gallus A0A1L1RM00 R-GGA-110317 https://reactome.org/PathwayBrowser/#/R-GGA-110317 Insertion of correct bases opposite the lesion by POLH IEA Gallus gallus A0A1L1RM00 R-GGA-110319 https://reactome.org/PathwayBrowser/#/R-GGA-110319 Elongation by POLH IEA Gallus gallus A0A1L1RM00 R-GGA-174439 https://reactome.org/PathwayBrowser/#/R-GGA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Gallus gallus A0A1L1RM00 R-GGA-174452 https://reactome.org/PathwayBrowser/#/R-GGA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Gallus gallus A0A1L1RM00 R-GGA-176101 https://reactome.org/PathwayBrowser/#/R-GGA-176101 Recruitment of Rad17-RFC complex to DNA IEA Gallus gallus A0A1L1RM00 R-GGA-176264 https://reactome.org/PathwayBrowser/#/R-GGA-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Gallus gallus A0A1L1RM00 R-GGA-5652005 https://reactome.org/PathwayBrowser/#/R-GGA-5652005 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA IEA Gallus gallus A0A1L1RM00 R-GGA-5652009 https://reactome.org/PathwayBrowser/#/R-GGA-5652009 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA IEA Gallus gallus A0A1L1RM00 R-GGA-5652151 https://reactome.org/PathwayBrowser/#/R-GGA-5652151 REV1 recruits POLZ to (AP:Cyt)-DNA Template IEA Gallus gallus A0A1L1RM00 R-GGA-5653756 https://reactome.org/PathwayBrowser/#/R-GGA-5653756 TRIM25 binds monoUb:164-PCNA IEA Gallus gallus A0A1L1RM00 R-GGA-5653766 https://reactome.org/PathwayBrowser/#/R-GGA-5653766 USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Gallus gallus A0A1L1RM00 R-GGA-5653770 https://reactome.org/PathwayBrowser/#/R-GGA-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Gallus gallus A0A1L1RM00 R-GGA-5653780 https://reactome.org/PathwayBrowser/#/R-GGA-5653780 USP43 binds ISG:K164,ISG:K168-PCNA IEA Gallus gallus A0A1L1RM00 R-GGA-5653838 https://reactome.org/PathwayBrowser/#/R-GGA-5653838 POLD,POLE binds deISGylated PCNA after TLS IEA Gallus gallus A0A1L1RM00 R-GGA-5654985 https://reactome.org/PathwayBrowser/#/R-GGA-5654985 SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH IEA Gallus gallus A0A1L1RM00 R-GGA-5654986 https://reactome.org/PathwayBrowser/#/R-GGA-5654986 SPRTN binds monoUb:K164-PCNA associated with POLH IEA Gallus gallus A0A1L1RM00 R-GGA-5654989 https://reactome.org/PathwayBrowser/#/R-GGA-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Gallus gallus A0A1L1RM00 R-GGA-5655466 https://reactome.org/PathwayBrowser/#/R-GGA-5655466 USP1:WDR48 deubiquitinates monoUb:K164-PCNA IEA Gallus gallus A0A1L1RM00 R-GGA-5655481 https://reactome.org/PathwayBrowser/#/R-GGA-5655481 USP1:WDR48 binds monoUb:K164-PCNA IEA Gallus gallus A0A1L1RM00 R-GGA-5655835 https://reactome.org/PathwayBrowser/#/R-GGA-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Gallus gallus A0A1L1RM00 R-GGA-5655892 https://reactome.org/PathwayBrowser/#/R-GGA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Gallus gallus A0A1L1RM00 R-GGA-5655965 https://reactome.org/PathwayBrowser/#/R-GGA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Gallus gallus A0A1L1RM00 R-GGA-5656148 https://reactome.org/PathwayBrowser/#/R-GGA-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Gallus gallus A0A1L1RM00 R-GGA-5656158 https://reactome.org/PathwayBrowser/#/R-GGA-5656158 POLZ elongates POLI-incorporated dNMP IEA Gallus gallus A0A1L1RM00 R-GGA-5685011 https://reactome.org/PathwayBrowser/#/R-GGA-5685011 ATR activation at DNA DSBs IEA Gallus gallus A0A1L1RM00 R-GGA-5685156 https://reactome.org/PathwayBrowser/#/R-GGA-5685156 ATR phosphorylates RPA2 IEA Gallus gallus A0A1L1RM00 R-GGA-5686642 https://reactome.org/PathwayBrowser/#/R-GGA-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Gallus gallus A0A1L1RM00 R-GGA-5690213 https://reactome.org/PathwayBrowser/#/R-GGA-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Gallus gallus A0A1L1RM00 R-GGA-5691001 https://reactome.org/PathwayBrowser/#/R-GGA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Gallus gallus A0A1L1RM00 R-GGA-5693564 https://reactome.org/PathwayBrowser/#/R-GGA-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Gallus gallus A0A1L1RM00 R-GGA-5693580 https://reactome.org/PathwayBrowser/#/R-GGA-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Gallus gallus A0A1L1RM00 R-GGA-5693593 https://reactome.org/PathwayBrowser/#/R-GGA-5693593 D-loop extension by DNA polymerases IEA Gallus gallus A0A1L1RM00 R-GGA-6782208 https://reactome.org/PathwayBrowser/#/R-GGA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Gallus gallus A0A1L1RM00 R-GGA-6782211 https://reactome.org/PathwayBrowser/#/R-GGA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Gallus gallus A0A1L1RM00 R-GGA-6782227 https://reactome.org/PathwayBrowser/#/R-GGA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Gallus gallus A0A1L1RM00 R-GGA-69053 https://reactome.org/PathwayBrowser/#/R-GGA-69053 RFC binding displaces Pol Alpha IEA Gallus gallus A0A1L1RM00 R-GGA-69063 https://reactome.org/PathwayBrowser/#/R-GGA-69063 Loading of PCNA - Sliding Clamp Formation IEA Gallus gallus A0A1L1RM00 R-GGA-69068 https://reactome.org/PathwayBrowser/#/R-GGA-69068 RFC dissociates after sliding clamp formation IEA Gallus gallus A0A1L1RM00 R-GGA-9668902 https://reactome.org/PathwayBrowser/#/R-GGA-9668902 Formation of the CTF18-RFC(7s) complex IEA Gallus gallus A0A1L1RM10 R-GGA-202165 https://reactome.org/PathwayBrowser/#/R-GGA-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Gallus gallus A0A1L1RM10 R-GGA-202168 https://reactome.org/PathwayBrowser/#/R-GGA-202168 Phosphorylation of ZAP-70 by Lck IEA Gallus gallus A0A1L1RM10 R-GGA-202174 https://reactome.org/PathwayBrowser/#/R-GGA-202174 Activation of ZAP-70 IEA Gallus gallus A0A1L1RM10 R-GGA-202214 https://reactome.org/PathwayBrowser/#/R-GGA-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Gallus gallus A0A1L1RM10 R-GGA-202233 https://reactome.org/PathwayBrowser/#/R-GGA-202233 Inactivation of Lck by Csk IEA Gallus gallus A0A1L1RM10 R-GGA-202248 https://reactome.org/PathwayBrowser/#/R-GGA-202248 Phosphorylation of PLC-gamma1 IEA Gallus gallus A0A1L1RM10 R-GGA-202291 https://reactome.org/PathwayBrowser/#/R-GGA-202291 Activation of Lck IEA Gallus gallus A0A1L1RM10 R-GGA-202344 https://reactome.org/PathwayBrowser/#/R-GGA-202344 Recruitment of ZAP-70 to phosphorylated ITAMs IEA Gallus gallus A0A1L1RM10 R-GGA-2130641 https://reactome.org/PathwayBrowser/#/R-GGA-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Gallus gallus A0A1L1RM10 R-GGA-2130725 https://reactome.org/PathwayBrowser/#/R-GGA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Gallus gallus A0A1L1RM10 R-GGA-389758 https://reactome.org/PathwayBrowser/#/R-GGA-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Gallus gallus A0A1L1RM10 R-GGA-8852200 https://reactome.org/PathwayBrowser/#/R-GGA-8852200 Inactivation of LCK by PTPN22 IEA Gallus gallus A0A1L1RM10 R-GGA-8855381 https://reactome.org/PathwayBrowser/#/R-GGA-8855381 PTPN22 dephosphorylates ZAP70 IEA Gallus gallus A0A1L1RM10 R-GGA-8951498 https://reactome.org/PathwayBrowser/#/R-GGA-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Gallus gallus A0A1L1RM23 R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus A0A1L1RM23 R-GGA-6799179 https://reactome.org/PathwayBrowser/#/R-GGA-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Gallus gallus A0A1L1RM23 R-GGA-6799196 https://reactome.org/PathwayBrowser/#/R-GGA-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Gallus gallus A0A1L1RM52 R-GGA-3247836 https://reactome.org/PathwayBrowser/#/R-GGA-3247836 Retromer recycles WLS to the Golgi IEA Gallus gallus A0A1L1RM52 R-GGA-3247839 https://reactome.org/PathwayBrowser/#/R-GGA-3247839 Retromer associates with WLS IEA Gallus gallus A0A1L1RM52 R-GGA-3247849 https://reactome.org/PathwayBrowser/#/R-GGA-3247849 WLS dissociates from retromer IEA Gallus gallus A0A1L1RM67 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1L1RM96 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1L1RMC0 R-GGA-1168640 https://reactome.org/PathwayBrowser/#/R-GGA-1168640 Ubiquitinated IkB is degraded IEA Gallus gallus A0A1L1RMC0 R-GGA-1234159 https://reactome.org/PathwayBrowser/#/R-GGA-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Gallus gallus A0A1L1RMC0 R-GGA-1236970 https://reactome.org/PathwayBrowser/#/R-GGA-1236970 Proteasomal clevage of exogenous antigen (26S proteasome catalyst) IEA Gallus gallus A0A1L1RMC0 R-GGA-1504193 https://reactome.org/PathwayBrowser/#/R-GGA-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-174058 https://reactome.org/PathwayBrowser/#/R-GGA-174058 Degradation of multiubiquitinated Cdh1 IEA Gallus gallus A0A1L1RMC0 R-GGA-174105 https://reactome.org/PathwayBrowser/#/R-GGA-174105 Degradation of multiubiquitinated cell cycle proteins IEA Gallus gallus A0A1L1RMC0 R-GGA-174202 https://reactome.org/PathwayBrowser/#/R-GGA-174202 Degradation of multiubiquitinated Securin IEA Gallus gallus A0A1L1RMC0 R-GGA-174255 https://reactome.org/PathwayBrowser/#/R-GGA-174255 Degradation multiubiquitinated Cyclin A IEA Gallus gallus A0A1L1RMC0 R-GGA-187574 https://reactome.org/PathwayBrowser/#/R-GGA-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-188191 https://reactome.org/PathwayBrowser/#/R-GGA-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Gallus gallus A0A1L1RMC0 R-GGA-209061 https://reactome.org/PathwayBrowser/#/R-GGA-209061 Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex IEA Gallus gallus A0A1L1RMC0 R-GGA-2130282 https://reactome.org/PathwayBrowser/#/R-GGA-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-264458 https://reactome.org/PathwayBrowser/#/R-GGA-264458 Proteasome mediated degradation of COP1 IEA Gallus gallus A0A1L1RMC0 R-GGA-353125 https://reactome.org/PathwayBrowser/#/R-GGA-353125 26S proteosome degrades ODC holoenzyme complex IEA Gallus gallus A0A1L1RMC0 R-GGA-3640874 https://reactome.org/PathwayBrowser/#/R-GGA-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-450466 https://reactome.org/PathwayBrowser/#/R-GGA-450466 AUF1:mRNA complex is destroyed IEA Gallus gallus A0A1L1RMC0 R-GGA-4608855 https://reactome.org/PathwayBrowser/#/R-GGA-4608855 PRICKLE1 is degraded by the proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-4641256 https://reactome.org/PathwayBrowser/#/R-GGA-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-5362448 https://reactome.org/PathwayBrowser/#/R-GGA-5362448 Hh C-terminal fragments are degraded by the proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-5607724 https://reactome.org/PathwayBrowser/#/R-GGA-5607724 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex IEA Gallus gallus A0A1L1RMC0 R-GGA-5610754 https://reactome.org/PathwayBrowser/#/R-GGA-5610754 GLI3 is partially degraded by the proteasome to yield the GLI3 repressor IEA Gallus gallus A0A1L1RMC0 R-GGA-5610758 https://reactome.org/PathwayBrowser/#/R-GGA-5610758 GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP IEA Gallus gallus A0A1L1RMC0 R-GGA-5610760 https://reactome.org/PathwayBrowser/#/R-GGA-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Gallus gallus A0A1L1RMC0 R-GGA-5635854 https://reactome.org/PathwayBrowser/#/R-GGA-5635854 GLI2,3 are degraded by the proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-5635868 https://reactome.org/PathwayBrowser/#/R-GGA-5635868 ub-GLI is degraded by the proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-5658430 https://reactome.org/PathwayBrowser/#/R-GGA-5658430 NF1 is degraded by the proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-5665854 https://reactome.org/PathwayBrowser/#/R-GGA-5665854 ADRM1:26S proteaseome binds UCHL5 IEA Gallus gallus A0A1L1RMC0 R-GGA-5665871 https://reactome.org/PathwayBrowser/#/R-GGA-5665871 ADRM1 binds 26S proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-5668481 https://reactome.org/PathwayBrowser/#/R-GGA-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Gallus gallus A0A1L1RMC0 R-GGA-5668520 https://reactome.org/PathwayBrowser/#/R-GGA-5668520 26Sproteasome degrades K48polyUb-NIK IEA Gallus gallus A0A1L1RMC0 R-GGA-5687112 https://reactome.org/PathwayBrowser/#/R-GGA-5687112 MAPK6 is degraded by the 26S proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-5689539 https://reactome.org/PathwayBrowser/#/R-GGA-5689539 ADRM1:26S proteaseome binds USP14 IEA Gallus gallus A0A1L1RMC0 R-GGA-68825 https://reactome.org/PathwayBrowser/#/R-GGA-68825 Ubiquitinated geminin is degraded by the proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-68948 https://reactome.org/PathwayBrowser/#/R-GGA-68948 Ubiquitinated Orc1 is degraded by the proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-69016 https://reactome.org/PathwayBrowser/#/R-GGA-69016 Ubiquitinated Cdc6 is degraded by the proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-69600 https://reactome.org/PathwayBrowser/#/R-GGA-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Gallus gallus A0A1L1RMC0 R-GGA-75825 https://reactome.org/PathwayBrowser/#/R-GGA-75825 Proteasome mediated degradation of Cyclin D1 IEA Gallus gallus A0A1L1RMC0 R-GGA-8850992 https://reactome.org/PathwayBrowser/#/R-GGA-8850992 Proteasome degrades polyubiquitinated PTEN IEA Gallus gallus A0A1L1RMC0 R-GGA-8854044 https://reactome.org/PathwayBrowser/#/R-GGA-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Gallus gallus A0A1L1RMC0 R-GGA-8854071 https://reactome.org/PathwayBrowser/#/R-GGA-8854071 Proteasome-mediated degradation of PolyUb-FBXL7 IEA Gallus gallus A0A1L1RMC0 R-GGA-8866553 https://reactome.org/PathwayBrowser/#/R-GGA-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-8932355 https://reactome.org/PathwayBrowser/#/R-GGA-8932355 26S proteasome degrades Ub-NFE2L2 IEA Gallus gallus A0A1L1RMC0 R-GGA-8939801 https://reactome.org/PathwayBrowser/#/R-GGA-8939801 26S proteasome degrades PolyUb-RUNX2 IEA Gallus gallus A0A1L1RMC0 R-GGA-8952408 https://reactome.org/PathwayBrowser/#/R-GGA-8952408 Polyubiquitinated RUNX3 is degraded by the proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-8956140 https://reactome.org/PathwayBrowser/#/R-GGA-8956140 NEDD8 and UBD bind NUB1 and the 26S proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-8956184 https://reactome.org/PathwayBrowser/#/R-GGA-8956184 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates IEA Gallus gallus A0A1L1RMC0 R-GGA-8957265 https://reactome.org/PathwayBrowser/#/R-GGA-8957265 26S proteasome degrades TP73 polyubiquitinated by ITCH IEA Gallus gallus A0A1L1RMC0 R-GGA-9755303 https://reactome.org/PathwayBrowser/#/R-GGA-9755303 26S proteasome degrades HIFalpha IEA Gallus gallus A0A1L1RMC0 R-GGA-9755306 https://reactome.org/PathwayBrowser/#/R-GGA-9755306 ub UBXN7 is degraded by the 26S proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-9762096 https://reactome.org/PathwayBrowser/#/R-GGA-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Gallus gallus A0A1L1RMC0 R-GGA-983150 https://reactome.org/PathwayBrowser/#/R-GGA-983150 Proteasomal cleavage of substrate IEA Gallus gallus A0A1L1RMC0 R-GGA-9907912 https://reactome.org/PathwayBrowser/#/R-GGA-9907912 Formation of the outer ring of the 20S core particle IEA Gallus gallus A0A1L1RMC0 R-GGA-9907919 https://reactome.org/PathwayBrowser/#/R-GGA-9907919 Formation of the preholoproteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-9907940 https://reactome.org/PathwayBrowser/#/R-GGA-9907940 Formation of the preholothymoproteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-9907941 https://reactome.org/PathwayBrowser/#/R-GGA-9907941 Fromation of the preholoimmunoproteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-9908052 https://reactome.org/PathwayBrowser/#/R-GGA-9908052 PSMG1:PSMG2 dimer binds the 20S core particle outer ring IEA Gallus gallus A0A1L1RMC0 R-GGA-9908069 https://reactome.org/PathwayBrowser/#/R-GGA-9908069 POMP binds the 20S core particle outer ring IEA Gallus gallus A0A1L1RMC0 R-GGA-9908721 https://reactome.org/PathwayBrowser/#/R-GGA-9908721 Formation of the PA28gamma-20S proteasome IEA Gallus gallus A0A1L1RMC0 R-GGA-9912636 https://reactome.org/PathwayBrowser/#/R-GGA-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Gallus gallus A0A1L1RMC0 R-GGA-9934893 https://reactome.org/PathwayBrowser/#/R-GGA-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 IEA Gallus gallus A0A1L1RMC6 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A1L1RMC6 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A1L1RMC6 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A1L1RMC6 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A1L1RMC6 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1L1RMC6 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1L1RMC6 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1L1RMC6 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1L1RMC6 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1L1RMC6 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A1L1RMC6 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1L1RMC6 R-GGA-9658445 https://reactome.org/PathwayBrowser/#/R-GGA-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Gallus gallus A0A1L1RMC6 R-GGA-9853372 https://reactome.org/PathwayBrowser/#/R-GGA-9853372 FIRRM binds PPP1CC IEA Gallus gallus A0A1L1RMC6 R-GGA-9853385 https://reactome.org/PathwayBrowser/#/R-GGA-9853385 PPP1CC dephosphorylates PLK1 IEA Gallus gallus A0A1L1RME9 R-GGA-5654985 https://reactome.org/PathwayBrowser/#/R-GGA-5654985 SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH IEA Gallus gallus A0A1L1RME9 R-GGA-5654989 https://reactome.org/PathwayBrowser/#/R-GGA-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Gallus gallus A0A1L1RME9 R-GGA-9755507 https://reactome.org/PathwayBrowser/#/R-GGA-9755507 UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex IEA Gallus gallus A0A1L1RME9 R-GGA-9758088 https://reactome.org/PathwayBrowser/#/R-GGA-9758088 UBXN7 binds VCP hexamer:UBF1:NPLOC4 IEA Gallus gallus A0A1L1RMG5 R-GGA-9018758 https://reactome.org/PathwayBrowser/#/R-GGA-9018758 RHOH binds effectors at the plasma membrane IEA Gallus gallus A0A1L1RMH1 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1L1RMH6 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus A0A1L1RMH6 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1L1RMH6 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1L1RMH6 R-GGA-8849350 https://reactome.org/PathwayBrowser/#/R-GGA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex IEA Gallus gallus A0A1L1RMH6 R-GGA-8849353 https://reactome.org/PathwayBrowser/#/R-GGA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER IEA Gallus gallus A0A1L1RML1 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1L1RML1 R-GGA-8853734 https://reactome.org/PathwayBrowser/#/R-GGA-8853734 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 IEA Gallus gallus A0A1L1RML1 R-GGA-8853737 https://reactome.org/PathwayBrowser/#/R-GGA-8853737 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 IEA Gallus gallus A0A1L1RML1 R-GGA-8853745 https://reactome.org/PathwayBrowser/#/R-GGA-8853745 RET binds GFRA1,GFRA3 IEA Gallus gallus A0A1L1RML1 R-GGA-8853753 https://reactome.org/PathwayBrowser/#/R-GGA-8853753 2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 IEA Gallus gallus A0A1L1RML1 R-GGA-8853755 https://reactome.org/PathwayBrowser/#/R-GGA-8853755 2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 IEA Gallus gallus A0A1L1RML1 R-GGA-8853762 https://reactome.org/PathwayBrowser/#/R-GGA-8853762 RET dimerizes IEA Gallus gallus A0A1L1RML1 R-GGA-8853774 https://reactome.org/PathwayBrowser/#/R-GGA-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Gallus gallus A0A1L1RML1 R-GGA-8853789 https://reactome.org/PathwayBrowser/#/R-GGA-8853789 GDNF,NRTN bind RET:GFRA1,GFRA2 IEA Gallus gallus A0A1L1RML1 R-GGA-8853792 https://reactome.org/PathwayBrowser/#/R-GGA-8853792 RET tyrosine phosphorylation IEA Gallus gallus A0A1L1RML1 R-GGA-8853793 https://reactome.org/PathwayBrowser/#/R-GGA-8853793 p-5Y-RET complexes bind GRB2 IEA Gallus gallus A0A1L1RML1 R-GGA-8853800 https://reactome.org/PathwayBrowser/#/R-GGA-8853800 ARTN binds RET:GFRA1,GFRA3 IEA Gallus gallus A0A1L1RML1 R-GGA-8854897 https://reactome.org/PathwayBrowser/#/R-GGA-8854897 p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2 IEA Gallus gallus A0A1L1RML1 R-GGA-8854899 https://reactome.org/PathwayBrowser/#/R-GGA-8854899 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 IEA Gallus gallus A0A1L1RML1 R-GGA-8854905 https://reactome.org/PathwayBrowser/#/R-GGA-8854905 p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K IEA Gallus gallus A0A1L1RML1 R-GGA-8854981 https://reactome.org/PathwayBrowser/#/R-GGA-8854981 SHC1 in the RET complex is phosphorylated IEA Gallus gallus A0A1L1RML1 R-GGA-8855508 https://reactome.org/PathwayBrowser/#/R-GGA-8855508 p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 IEA Gallus gallus A0A1L1RML1 R-GGA-8855564 https://reactome.org/PathwayBrowser/#/R-GGA-8855564 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 IEA Gallus gallus A0A1L1RML1 R-GGA-8855617 https://reactome.org/PathwayBrowser/#/R-GGA-8855617 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 IEA Gallus gallus A0A1L1RML1 R-GGA-8855747 https://reactome.org/PathwayBrowser/#/R-GGA-8855747 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP IEA Gallus gallus A0A1L1RML1 R-GGA-8855915 https://reactome.org/PathwayBrowser/#/R-GGA-8855915 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors IEA Gallus gallus A0A1L1RML1 R-GGA-8871226 https://reactome.org/PathwayBrowser/#/R-GGA-8871226 RET binds GFRA1,GFRA2 IEA Gallus gallus A0A1L1RML1 R-GGA-8871227 https://reactome.org/PathwayBrowser/#/R-GGA-8871227 RET binds GFRA4 IEA Gallus gallus A0A1L1RMM0 R-GGA-391266 https://reactome.org/PathwayBrowser/#/R-GGA-391266 Association of CCT/TriC with sphingosine kinase 1 IEA Gallus gallus A0A1L1RMM0 R-GGA-6814119 https://reactome.org/PathwayBrowser/#/R-GGA-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Gallus gallus A0A1L1RMM0 R-GGA-6814120 https://reactome.org/PathwayBrowser/#/R-GGA-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Gallus gallus A0A1L1RMM0 R-GGA-6814121 https://reactome.org/PathwayBrowser/#/R-GGA-6814121 PDCL binds G-protein beta and TRiC/CCT IEA Gallus gallus A0A1L1RMM0 R-GGA-6814124 https://reactome.org/PathwayBrowser/#/R-GGA-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Gallus gallus A0A1L1RMM0 R-GGA-8850527 https://reactome.org/PathwayBrowser/#/R-GGA-8850527 PDCL releases folded G-beta from TRiC/CCT IEA Gallus gallus A0A1L1RMM0 R-GGA-8850529 https://reactome.org/PathwayBrowser/#/R-GGA-8850529 RGS proteins bind GNB5 and CCT/TRiC IEA Gallus gallus A0A1L1RMM0 R-GGA-8850534 https://reactome.org/PathwayBrowser/#/R-GGA-8850534 PDCL promotes G-protein beta 5 folding IEA Gallus gallus A0A1L1RMM0 R-GGA-8850539 https://reactome.org/PathwayBrowser/#/R-GGA-8850539 Release of GNB5:RGS dimers from CCT/TRiC IEA Gallus gallus A0A1L1RMP9 R-GGA-6811431 https://reactome.org/PathwayBrowser/#/R-GGA-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Gallus gallus A0A1L1RMP9 R-GGA-6814086 https://reactome.org/PathwayBrowser/#/R-GGA-6814086 ARFRP1 recruits ARL1 to the TGN IEA Gallus gallus A0A1L1RMP9 R-GGA-6814091 https://reactome.org/PathwayBrowser/#/R-GGA-6814091 ARL1 recruits TGN Golgin homodimers IEA Gallus gallus A0A1L1RMP9 R-GGA-6814094 https://reactome.org/PathwayBrowser/#/R-GGA-6814094 ARL1:GTP binds ARFIP2 IEA Gallus gallus A0A1L1RMP9 R-GGA-6814096 https://reactome.org/PathwayBrowser/#/R-GGA-6814096 ARL1:GTP binds SCOC IEA Gallus gallus A0A1L1RMP9 R-GGA-6814682 https://reactome.org/PathwayBrowser/#/R-GGA-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Gallus gallus A0A1L1RMQ9 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1L1RMR6 R-GGA-5624126 https://reactome.org/PathwayBrowser/#/R-GGA-5624126 ARL6:GTP and the BBSome bind ciliary cargo IEA Gallus gallus A0A1L1RMR6 R-GGA-5624127 https://reactome.org/PathwayBrowser/#/R-GGA-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Gallus gallus A0A1L1RMV7 R-GGA-5362522 https://reactome.org/PathwayBrowser/#/R-GGA-5362522 ALDHs oxidise atRAL to atRA IEA Gallus gallus A0A1L1RMY8 R-GGA-2248891 https://reactome.org/PathwayBrowser/#/R-GGA-2248891 M6PR transports activated ARSA to the lysosome IEA Gallus gallus A0A1L1RMY8 R-GGA-432706 https://reactome.org/PathwayBrowser/#/R-GGA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Gallus gallus A0A1L1RMY8 R-GGA-432707 https://reactome.org/PathwayBrowser/#/R-GGA-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Gallus gallus A0A1L1RMY8 R-GGA-6814670 https://reactome.org/PathwayBrowser/#/R-GGA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation IEA Gallus gallus A0A1L1RMY8 R-GGA-6814671 https://reactome.org/PathwayBrowser/#/R-GGA-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Gallus gallus A0A1L1RMY8 R-GGA-6814675 https://reactome.org/PathwayBrowser/#/R-GGA-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN IEA Gallus gallus A0A1L1RMY8 R-GGA-8866277 https://reactome.org/PathwayBrowser/#/R-GGA-8866277 AP-2 directly binds some endocytic cargo IEA Gallus gallus A0A1L1RMY8 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1L1RMY8 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1L1RMY8 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1L1RMY8 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1L1RMY8 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1L1RMY8 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1L1RMY8 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1L1RMY8 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1L1RMY8 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1L1RMY8 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1L1RMY8 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1L1RMY8 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1L1RMZ7 R-GGA-6811428 https://reactome.org/PathwayBrowser/#/R-GGA-6811428 RIC1:RGP1 recruits RAB6:GDP to the TGN IEA Gallus gallus A0A1L1RMZ7 R-GGA-6811429 https://reactome.org/PathwayBrowser/#/R-GGA-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange IEA Gallus gallus A0A1L1RMZ7 R-GGA-6811431 https://reactome.org/PathwayBrowser/#/R-GGA-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles IEA Gallus gallus A0A1L1RMZ7 R-GGA-6814682 https://reactome.org/PathwayBrowser/#/R-GGA-6814682 Fusion of early-endosome derived vesicles at the TGN IEA Gallus gallus A0A1L1RMZ7 R-GGA-8847887 https://reactome.org/PathwayBrowser/#/R-GGA-8847887 RAB33B:GTP binds RIC1:RGP1 IEA Gallus gallus A0A1L1RMZ7 R-GGA-8876193 https://reactome.org/PathwayBrowser/#/R-GGA-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 IEA Gallus gallus A0A1L1RN02 R-GGA-1236940 https://reactome.org/PathwayBrowser/#/R-GGA-1236940 Exogenous soluble antigen targeted to more stable early endosome IEA Gallus gallus A0A1L1RN02 R-GGA-1236941 https://reactome.org/PathwayBrowser/#/R-GGA-1236941 Internalization of receptor bound antigen into clathrin coted vesicles IEA Gallus gallus A0A1L1RN02 R-GGA-1236955 https://reactome.org/PathwayBrowser/#/R-GGA-1236955 Movement of clathrin coated vesicles into early endosome IEA Gallus gallus A0A1L1RN02 R-GGA-8851018 https://reactome.org/PathwayBrowser/#/R-GGA-8851018 BTN2A1 binds DC-SIGN IEA Gallus gallus A0A1L1RN02 R-GGA-8855711 https://reactome.org/PathwayBrowser/#/R-GGA-8855711 PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins IEA Gallus gallus A0A1L1RN02 R-GGA-8858500 https://reactome.org/PathwayBrowser/#/R-GGA-8858500 CLEC10A binds Tn-MUC1 IEA Gallus gallus A0A1L1RN25 R-GGA-9733964 https://reactome.org/PathwayBrowser/#/R-GGA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Gallus gallus A0A1L1RN55 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus A0A1L1RN70 R-GGA-109637 https://reactome.org/PathwayBrowser/#/R-GGA-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Gallus gallus A0A1L1RN70 R-GGA-109638 https://reactome.org/PathwayBrowser/#/R-GGA-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Gallus gallus A0A1L1RN70 R-GGA-109639 https://reactome.org/PathwayBrowser/#/R-GGA-109639 Formation of the closed pre-initiation complex IEA Gallus gallus A0A1L1RN70 R-GGA-6810233 https://reactome.org/PathwayBrowser/#/R-GGA-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Gallus gallus A0A1L1RN70 R-GGA-6810235 https://reactome.org/PathwayBrowser/#/R-GGA-6810235 RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain IEA Gallus gallus A0A1L1RN70 R-GGA-6810238 https://reactome.org/PathwayBrowser/#/R-GGA-6810238 RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) IEA Gallus gallus A0A1L1RN70 R-GGA-6814555 https://reactome.org/PathwayBrowser/#/R-GGA-6814555 Integrator complex processes the 3' end of snRNA IEA Gallus gallus A0A1L1RN70 R-GGA-6814559 https://reactome.org/PathwayBrowser/#/R-GGA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Gallus gallus A0A1L1RN70 R-GGA-73946 https://reactome.org/PathwayBrowser/#/R-GGA-73946 Abortive initiation after formation of the first phosphodiester bond IEA Gallus gallus A0A1L1RN70 R-GGA-75095 https://reactome.org/PathwayBrowser/#/R-GGA-75095 Binding of TFIIE to the growing preinitiation complex IEA Gallus gallus A0A1L1RN70 R-GGA-75850 https://reactome.org/PathwayBrowser/#/R-GGA-75850 Addition of the third nucleotide on the nascent transcript IEA Gallus gallus A0A1L1RN70 R-GGA-75856 https://reactome.org/PathwayBrowser/#/R-GGA-75856 Abortive Initiation Before Second Transition IEA Gallus gallus A0A1L1RN70 R-GGA-75861 https://reactome.org/PathwayBrowser/#/R-GGA-75861 NTP Binds Active Site of RNA Polymerase II IEA Gallus gallus A0A1L1RN70 R-GGA-75862 https://reactome.org/PathwayBrowser/#/R-GGA-75862 Fall Back to Closed Pre-initiation Complex IEA Gallus gallus A0A1L1RN70 R-GGA-75864 https://reactome.org/PathwayBrowser/#/R-GGA-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Gallus gallus A0A1L1RN70 R-GGA-75866 https://reactome.org/PathwayBrowser/#/R-GGA-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Gallus gallus A0A1L1RN70 R-GGA-75869 https://reactome.org/PathwayBrowser/#/R-GGA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Gallus gallus A0A1L1RN70 R-GGA-75949 https://reactome.org/PathwayBrowser/#/R-GGA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Gallus gallus A0A1L1RN70 R-GGA-9613494 https://reactome.org/PathwayBrowser/#/R-GGA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Gallus gallus A0A1L1RN70 R-GGA-9613497 https://reactome.org/PathwayBrowser/#/R-GGA-9613497 Unwinding DNA for the nascent transcript IEA Gallus gallus A0A1L1RN99 R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus A0A1L1RN99 R-GGA-9011543 https://reactome.org/PathwayBrowser/#/R-GGA-9011543 DCA binds PDK2 IEA Gallus gallus A0A1L1RND0 R-GGA-1497784 https://reactome.org/PathwayBrowser/#/R-GGA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Gallus gallus A0A1L1RND0 R-GGA-1497796 https://reactome.org/PathwayBrowser/#/R-GGA-1497796 BH2 binding can lead to eNOS uncoupling IEA Gallus gallus A0A1L1RND0 R-GGA-1497810 https://reactome.org/PathwayBrowser/#/R-GGA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Gallus gallus A0A1L1RND0 R-GGA-1918092 https://reactome.org/PathwayBrowser/#/R-GGA-1918092 CHIP (STUB1) mediates ubiquitination of ERBB2 IEA Gallus gallus A0A1L1RND0 R-GGA-1918095 https://reactome.org/PathwayBrowser/#/R-GGA-1918095 CUL5 mediates ubiquitination of ERBB2 IEA Gallus gallus A0A1L1RND0 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus A0A1L1RND0 R-GGA-202111 https://reactome.org/PathwayBrowser/#/R-GGA-202111 AKT1 phosphorylates eNOS IEA Gallus gallus A0A1L1RND0 R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus A0A1L1RND0 R-GGA-202129 https://reactome.org/PathwayBrowser/#/R-GGA-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Gallus gallus A0A1L1RND0 R-GGA-202137 https://reactome.org/PathwayBrowser/#/R-GGA-202137 AKT1 binds eNOS complex via HSP90 IEA Gallus gallus A0A1L1RND0 R-GGA-202144 https://reactome.org/PathwayBrowser/#/R-GGA-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Gallus gallus A0A1L1RND0 R-GGA-2574840 https://reactome.org/PathwayBrowser/#/R-GGA-2574840 AJUBA facilitates AURKA autophosphorylation IEA Gallus gallus A0A1L1RND0 R-GGA-2574845 https://reactome.org/PathwayBrowser/#/R-GGA-2574845 AJUBA binds centrosome-associated AURKA IEA Gallus gallus A0A1L1RND0 R-GGA-3000310 https://reactome.org/PathwayBrowser/#/R-GGA-3000310 AURKA phosphorylates PLK1 IEA Gallus gallus A0A1L1RND0 R-GGA-3000319 https://reactome.org/PathwayBrowser/#/R-GGA-3000319 BORA binds PLK1 and AURKA IEA Gallus gallus A0A1L1RND0 R-GGA-3371503 https://reactome.org/PathwayBrowser/#/R-GGA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Gallus gallus A0A1L1RND0 R-GGA-3371586 https://reactome.org/PathwayBrowser/#/R-GGA-3371586 Dissociation of cytosolic HSF1:HSP90 complex IEA Gallus gallus A0A1L1RND0 R-GGA-380272 https://reactome.org/PathwayBrowser/#/R-GGA-380272 Plk1-mediated phosphorylation of Nlp IEA Gallus gallus A0A1L1RND0 R-GGA-380283 https://reactome.org/PathwayBrowser/#/R-GGA-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Gallus gallus A0A1L1RND0 R-GGA-380294 https://reactome.org/PathwayBrowser/#/R-GGA-380294 Loss of C-Nap-1 from centrosomes IEA Gallus gallus A0A1L1RND0 R-GGA-380311 https://reactome.org/PathwayBrowser/#/R-GGA-380311 Recruitment of Plk1 to centrosomes IEA Gallus gallus A0A1L1RND0 R-GGA-380455 https://reactome.org/PathwayBrowser/#/R-GGA-380455 Recruitment of CDK11p58 to the centrosomes IEA Gallus gallus A0A1L1RND0 R-GGA-380508 https://reactome.org/PathwayBrowser/#/R-GGA-380508 Translocation of NuMA to the centrosomes IEA Gallus gallus A0A1L1RND0 R-GGA-3928647 https://reactome.org/PathwayBrowser/#/R-GGA-3928647 RHOA:GTP:Mg2+ binds ROCK1,ROCK2 IEA Gallus gallus A0A1L1RND0 R-GGA-419644 https://reactome.org/PathwayBrowser/#/R-GGA-419644 Transphosphorylation of pLIMK1 IEA Gallus gallus A0A1L1RND0 R-GGA-419645 https://reactome.org/PathwayBrowser/#/R-GGA-419645 Dimerization of LIMK1 by Hsp90 IEA Gallus gallus A0A1L1RND0 R-GGA-5082356 https://reactome.org/PathwayBrowser/#/R-GGA-5082356 HSF1-mediated gene expression IEA Gallus gallus A0A1L1RND0 R-GGA-5082409 https://reactome.org/PathwayBrowser/#/R-GGA-5082409 Dissociation of HSF1:HSP90 complex in the nucleus IEA Gallus gallus A0A1L1RND0 R-GGA-5218643 https://reactome.org/PathwayBrowser/#/R-GGA-5218643 HSP90AA1 binds p-6Y-VEGFR2 IEA Gallus gallus A0A1L1RND0 R-GGA-5218809 https://reactome.org/PathwayBrowser/#/R-GGA-5218809 PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 IEA Gallus gallus A0A1L1RND0 R-GGA-5218811 https://reactome.org/PathwayBrowser/#/R-GGA-5218811 DOCK180:ELMO binds CRK IEA Gallus gallus A0A1L1RND0 R-GGA-5218822 https://reactome.org/PathwayBrowser/#/R-GGA-5218822 CRK binds BCAR1 and or PXN IEA Gallus gallus A0A1L1RND0 R-GGA-5218826 https://reactome.org/PathwayBrowser/#/R-GGA-5218826 Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 IEA Gallus gallus A0A1L1RND0 R-GGA-5218838 https://reactome.org/PathwayBrowser/#/R-GGA-5218838 PXN binds p-6Y,S732-PTK2 IEA Gallus gallus A0A1L1RND0 R-GGA-5218839 https://reactome.org/PathwayBrowser/#/R-GGA-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Gallus gallus A0A1L1RND0 R-GGA-5218851 https://reactome.org/PathwayBrowser/#/R-GGA-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 IEA Gallus gallus A0A1L1RND0 R-GGA-5324617 https://reactome.org/PathwayBrowser/#/R-GGA-5324617 HSP90:FKBP4:PTGES3 binds HSF1 trimer IEA Gallus gallus A0A1L1RND0 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1L1RND0 R-GGA-5618073 https://reactome.org/PathwayBrowser/#/R-GGA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Gallus gallus A0A1L1RND0 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus A0A1L1RND0 R-GGA-5618085 https://reactome.org/PathwayBrowser/#/R-GGA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Gallus gallus A0A1L1RND0 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus A0A1L1RND0 R-GGA-5618098 https://reactome.org/PathwayBrowser/#/R-GGA-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Gallus gallus A0A1L1RND0 R-GGA-5618099 https://reactome.org/PathwayBrowser/#/R-GGA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Gallus gallus A0A1L1RND0 R-GGA-5618105 https://reactome.org/PathwayBrowser/#/R-GGA-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Gallus gallus A0A1L1RND0 R-GGA-5618107 https://reactome.org/PathwayBrowser/#/R-GGA-5618107 ATP binding to HSP90 triggers conformation change IEA Gallus gallus A0A1L1RND0 R-GGA-5618110 https://reactome.org/PathwayBrowser/#/R-GGA-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Gallus gallus A0A1L1RND0 R-GGA-5626228 https://reactome.org/PathwayBrowser/#/R-GGA-5626228 The distal appendage proteins recruit TTBK2 IEA Gallus gallus A0A1L1RND0 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1L1RND0 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1L1RND0 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1L1RND0 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1L1RND0 R-GGA-8852362 https://reactome.org/PathwayBrowser/#/R-GGA-8852362 GTSE1 binds CDKN1A IEA Gallus gallus A0A1L1RND0 R-GGA-8853405 https://reactome.org/PathwayBrowser/#/R-GGA-8853405 TPX2 binds AURKA at centrosomes IEA Gallus gallus A0A1L1RND0 R-GGA-8853419 https://reactome.org/PathwayBrowser/#/R-GGA-8853419 TPX2 promotes AURKA autophosphorylation IEA Gallus gallus A0A1L1RND0 R-GGA-8939204 https://reactome.org/PathwayBrowser/#/R-GGA-8939204 ESTG binds ESR1:chaperone complex IEA Gallus gallus A0A1L1RND0 R-GGA-9018785 https://reactome.org/PathwayBrowser/#/R-GGA-9018785 RHOBTB2 binds GTP IEA Gallus gallus A0A1L1RND0 R-GGA-9038161 https://reactome.org/PathwayBrowser/#/R-GGA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Gallus gallus A0A1L1RND0 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus A0A1L1RND0 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus A0A1L1RND0 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus A0A1L1RND0 R-GGA-9698844 https://reactome.org/PathwayBrowser/#/R-GGA-9698844 MLKL binds HSP90:CDC37 IEA Gallus gallus A0A1L1RND0 R-GGA-9705925 https://reactome.org/PathwayBrowser/#/R-GGA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Gallus gallus A0A1L1RND0 R-GGA-9705926 https://reactome.org/PathwayBrowser/#/R-GGA-9705926 AR binds AR agonists IEA Gallus gallus A0A1L1RND0 R-GGA-9706837 https://reactome.org/PathwayBrowser/#/R-GGA-9706837 AR binds AR antagonists IEA Gallus gallus A0A1L1RND0 R-GGA-9709547 https://reactome.org/PathwayBrowser/#/R-GGA-9709547 ESTG binds ESR2:chaperone complex IEA Gallus gallus A0A1L1RND0 R-GGA-9716913 https://reactome.org/PathwayBrowser/#/R-GGA-9716913 ESR1 binds ESR1 antagonists IEA Gallus gallus A0A1L1RND0 R-GGA-9716947 https://reactome.org/PathwayBrowser/#/R-GGA-9716947 ESR1 binds ESR1 agonists IEA Gallus gallus A0A1L1RND0 R-GGA-9725855 https://reactome.org/PathwayBrowser/#/R-GGA-9725855 NR3C2 binds NR3C2 antagonists IEA Gallus gallus A0A1L1RND0 R-GGA-9725885 https://reactome.org/PathwayBrowser/#/R-GGA-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Gallus gallus A0A1L1RND0 R-GGA-9726509 https://reactome.org/PathwayBrowser/#/R-GGA-9726509 NR3C2 binds fludrocortisone IEA Gallus gallus A0A1L1RND0 R-GGA-9726580 https://reactome.org/PathwayBrowser/#/R-GGA-9726580 PGR binds PGR agonists IEA Gallus gallus A0A1L1RND0 R-GGA-9726621 https://reactome.org/PathwayBrowser/#/R-GGA-9726621 PGR binds PGR antagonists IEA Gallus gallus A0A1L1RND8 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1L1RND8 R-GGA-983152 https://reactome.org/PathwayBrowser/#/R-GGA-983152 Transfer of ubiquitin from E1 to E2 IEA Gallus gallus A0A1L1RND8 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1L1RND8 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1L1RNG1 R-GGA-1306876 https://reactome.org/PathwayBrowser/#/R-GGA-1306876 NLRP3 activation by small molecules IEA Gallus gallus A0A1L1RNG1 R-GGA-5691439 https://reactome.org/PathwayBrowser/#/R-GGA-5691439 BRISC complex deubiquitinates NLRP3 IEA Gallus gallus A0A1L1RNG1 R-GGA-873951 https://reactome.org/PathwayBrowser/#/R-GGA-873951 SGT1:HSP90 binds inactive NLRP3 IEA Gallus gallus A0A1L1RNG8 R-GGA-1482533 https://reactome.org/PathwayBrowser/#/R-GGA-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Gallus gallus A0A1L1RNG8 R-GGA-1482547 https://reactome.org/PathwayBrowser/#/R-GGA-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Gallus gallus A0A1L1RNG8 R-GGA-1482636 https://reactome.org/PathwayBrowser/#/R-GGA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Gallus gallus A0A1L1RNG8 R-GGA-1482646 https://reactome.org/PathwayBrowser/#/R-GGA-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Gallus gallus A0A1L1RNG8 R-GGA-1482667 https://reactome.org/PathwayBrowser/#/R-GGA-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Gallus gallus A0A1L1RNG8 R-GGA-1482691 https://reactome.org/PathwayBrowser/#/R-GGA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Gallus gallus A0A1L1RNH7 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1L1RNH7 R-GGA-6805546 https://reactome.org/PathwayBrowser/#/R-GGA-6805546 Keratin type I binds keratin type II IEA Gallus gallus A0A1L1RNH7 R-GGA-6805573 https://reactome.org/PathwayBrowser/#/R-GGA-6805573 Keratin type I/type II heterodimers form tetramers IEA Gallus gallus A0A1L1RNH7 R-GGA-6806610 https://reactome.org/PathwayBrowser/#/R-GGA-6806610 Keratin filament formation IEA Gallus gallus A0A1L1RNH7 R-GGA-6806613 https://reactome.org/PathwayBrowser/#/R-GGA-6806613 Keratin tetramers bind to form unit length filaments IEA Gallus gallus A0A1L1RNH7 R-GGA-6806629 https://reactome.org/PathwayBrowser/#/R-GGA-6806629 Formation of tonofilament bundles IEA Gallus gallus A0A1L1RNH7 R-GGA-6809393 https://reactome.org/PathwayBrowser/#/R-GGA-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Gallus gallus A0A1L1RNH7 R-GGA-6810357 https://reactome.org/PathwayBrowser/#/R-GGA-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Gallus gallus A0A1L1RNJ0 R-GGA-6797803 https://reactome.org/PathwayBrowser/#/R-GGA-6797803 PTPRD binds SLITRK1-6 IEA Gallus gallus A0A1L1RNL7 R-GGA-111439 https://reactome.org/PathwayBrowser/#/R-GGA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Gallus gallus A0A1L1RNL7 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A1L1RNL7 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A1L1RNL7 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A1L1RNL7 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A1L1RNL7 R-GGA-158441 https://reactome.org/PathwayBrowser/#/R-GGA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1L1RNL7 R-GGA-158447 https://reactome.org/PathwayBrowser/#/R-GGA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Gallus gallus A0A1L1RNL7 R-GGA-158481 https://reactome.org/PathwayBrowser/#/R-GGA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1L1RNL7 R-GGA-158484 https://reactome.org/PathwayBrowser/#/R-GGA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Gallus gallus A0A1L1RNL7 R-GGA-159046 https://reactome.org/PathwayBrowser/#/R-GGA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Gallus gallus A0A1L1RNL7 R-GGA-159050 https://reactome.org/PathwayBrowser/#/R-GGA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Gallus gallus A0A1L1RNL7 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1L1RNL7 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1L1RNL7 R-GGA-170825 https://reactome.org/PathwayBrowser/#/R-GGA-170825 NPC exports GCK1 from nucleus IEA Gallus gallus A0A1L1RNL7 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1L1RNL7 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus A0A1L1RNL7 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus A0A1L1RNL7 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1L1RNL7 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1L1RNL7 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1L1RNL7 R-GGA-2990880 https://reactome.org/PathwayBrowser/#/R-GGA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Gallus gallus A0A1L1RNL7 R-GGA-2990882 https://reactome.org/PathwayBrowser/#/R-GGA-2990882 CDK1 phosphorylates NUP98 IEA Gallus gallus A0A1L1RNL7 R-GGA-4551649 https://reactome.org/PathwayBrowser/#/R-GGA-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Gallus gallus A0A1L1RNL7 R-GGA-4551679 https://reactome.org/PathwayBrowser/#/R-GGA-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Gallus gallus A0A1L1RNL7 R-GGA-4615872 https://reactome.org/PathwayBrowser/#/R-GGA-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Gallus gallus A0A1L1RNL7 R-GGA-4615987 https://reactome.org/PathwayBrowser/#/R-GGA-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Gallus gallus A0A1L1RNL7 R-GGA-5228523 https://reactome.org/PathwayBrowser/#/R-GGA-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Gallus gallus A0A1L1RNL7 R-GGA-5578744 https://reactome.org/PathwayBrowser/#/R-GGA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Gallus gallus A0A1L1RNL7 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A1L1RNL7 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus A0A1L1RNL7 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus A0A1L1RNL7 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1L1RNL7 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1L1RNL7 R-GGA-77587 https://reactome.org/PathwayBrowser/#/R-GGA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Gallus gallus A0A1L1RNL7 R-GGA-9615901 https://reactome.org/PathwayBrowser/#/R-GGA-9615901 AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex IEA Gallus gallus A0A1L1RNL7 R-GGA-9618378 https://reactome.org/PathwayBrowser/#/R-GGA-9618378 POM121 binds the Nup107-Nup160 complex IEA Gallus gallus A0A1L1RNL7 R-GGA-9634169 https://reactome.org/PathwayBrowser/#/R-GGA-9634169 POM121 and NDC1 bind the Nup93 complex IEA Gallus gallus A0A1L1RNL7 R-GGA-9639287 https://reactome.org/PathwayBrowser/#/R-GGA-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Gallus gallus A0A1L1RNL7 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus A0A1L1RNL7 R-GGA-9640237 https://reactome.org/PathwayBrowser/#/R-GGA-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Gallus gallus A0A1L1RNL7 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1L1RNL7 R-GGA-9657619 https://reactome.org/PathwayBrowser/#/R-GGA-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 IEA Gallus gallus A0A1L1RNL7 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus A0A1L1RNL7 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus A0A1L1RNL7 R-GGA-983425 https://reactome.org/PathwayBrowser/#/R-GGA-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Gallus gallus A0A1L1RNM3 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1L1RNN4 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus A0A1L1RNR4 R-GGA-158218 https://reactome.org/PathwayBrowser/#/R-GGA-158218 prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer IEA Gallus gallus A0A1L1RNR4 R-GGA-158251 https://reactome.org/PathwayBrowser/#/R-GGA-158251 prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer IEA Gallus gallus A0A1L1RNR4 R-GGA-158311 https://reactome.org/PathwayBrowser/#/R-GGA-158311 kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin IEA Gallus gallus A0A1L1RNR4 R-GGA-158354 https://reactome.org/PathwayBrowser/#/R-GGA-158354 kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer IEA Gallus gallus A0A1L1RNR4 R-GGA-374331 https://reactome.org/PathwayBrowser/#/R-GGA-374331 Bradykinin receptors B1 and B2 bind to bradykinin IEA Gallus gallus A0A1L1RNR4 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1L1RNR4 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1L1RNR4 R-GGA-481007 https://reactome.org/PathwayBrowser/#/R-GGA-481007 Exocytosis of platelet alpha granule contents IEA Gallus gallus A0A1L1RNR4 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1L1RNR4 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1L1RNR4 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1L1RNR4 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1L1RNR4 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1L1RNS0 R-GGA-70494 https://reactome.org/PathwayBrowser/#/R-GGA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Gallus gallus A0A1L1RNS0 R-GGA-71660 https://reactome.org/PathwayBrowser/#/R-GGA-71660 Enolase dimers dehydrates 2PG IEA Gallus gallus A0A1L1RNV7 R-GGA-1112666 https://reactome.org/PathwayBrowser/#/R-GGA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Gallus gallus A0A1L1RNV7 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus A0A1L1RNV7 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus A0A1L1RNV7 R-GGA-173626 https://reactome.org/PathwayBrowser/#/R-GGA-173626 Activation of C1r IEA Gallus gallus A0A1L1RNV7 R-GGA-173631 https://reactome.org/PathwayBrowser/#/R-GGA-173631 Activation of C1s IEA Gallus gallus A0A1L1RNV7 R-GGA-1861621 https://reactome.org/PathwayBrowser/#/R-GGA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Gallus gallus A0A1L1RNV7 R-GGA-199161 https://reactome.org/PathwayBrowser/#/R-GGA-199161 Fc gamma receptors interact with antigen-bound IgG IEA Gallus gallus A0A1L1RNV7 R-GGA-2029268 https://reactome.org/PathwayBrowser/#/R-GGA-2029268 Phosphorylation and activation of PLCG IEA Gallus gallus A0A1L1RNV7 R-GGA-2029270 https://reactome.org/PathwayBrowser/#/R-GGA-2029270 Recruitment of PLCgamma to membrane IEA Gallus gallus A0A1L1RNV7 R-GGA-2029271 https://reactome.org/PathwayBrowser/#/R-GGA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1L1RNV7 R-GGA-2029272 https://reactome.org/PathwayBrowser/#/R-GGA-2029272 Release of PLCG from FCGR IEA Gallus gallus A0A1L1RNV7 R-GGA-2029273 https://reactome.org/PathwayBrowser/#/R-GGA-2029273 PI3K binds to p-6Y-SYK IEA Gallus gallus A0A1L1RNV7 R-GGA-2029451 https://reactome.org/PathwayBrowser/#/R-GGA-2029451 Activation of RAC1 by VAV IEA Gallus gallus A0A1L1RNV7 R-GGA-2029452 https://reactome.org/PathwayBrowser/#/R-GGA-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Gallus gallus A0A1L1RNV7 R-GGA-2029453 https://reactome.org/PathwayBrowser/#/R-GGA-2029453 Phosphorylation of VAV IEA Gallus gallus A0A1L1RNV7 R-GGA-2029455 https://reactome.org/PathwayBrowser/#/R-GGA-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Gallus gallus A0A1L1RNV7 R-GGA-2029457 https://reactome.org/PathwayBrowser/#/R-GGA-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Gallus gallus A0A1L1RNV7 R-GGA-2029458 https://reactome.org/PathwayBrowser/#/R-GGA-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Gallus gallus A0A1L1RNV7 R-GGA-2029459 https://reactome.org/PathwayBrowser/#/R-GGA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Gallus gallus A0A1L1RNV7 R-GGA-2029467 https://reactome.org/PathwayBrowser/#/R-GGA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Gallus gallus A0A1L1RNV7 R-GGA-2029476 https://reactome.org/PathwayBrowser/#/R-GGA-2029476 Role of myosins in phagosome formation IEA Gallus gallus A0A1L1RNV7 R-GGA-2197697 https://reactome.org/PathwayBrowser/#/R-GGA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Gallus gallus A0A1L1RNV7 R-GGA-2203516 https://reactome.org/PathwayBrowser/#/R-GGA-2203516 Alpha-1-Microglobulin is cleaved IEA Gallus gallus A0A1L1RNV7 R-GGA-8852266 https://reactome.org/PathwayBrowser/#/R-GGA-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Gallus gallus A0A1L1RNV7 R-GGA-8852481 https://reactome.org/PathwayBrowser/#/R-GGA-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Gallus gallus A0A1L1RNV7 R-GGA-8858428 https://reactome.org/PathwayBrowser/#/R-GGA-8858428 FCAMR binds IgA IEA Gallus gallus A0A1L1RNV7 R-GGA-9021306 https://reactome.org/PathwayBrowser/#/R-GGA-9021306 C1-Inh binds and inactivates C1r, C1s IEA Gallus gallus A0A1L1RNV7 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus A0A1L1RNV7 R-GGA-9724685 https://reactome.org/PathwayBrowser/#/R-GGA-9724685 IgE binds omalizumab IEA Gallus gallus A0A1L1RNV7 R-GGA-983696 https://reactome.org/PathwayBrowser/#/R-GGA-983696 The Immunoglobulin of the BCR binds antigen IEA Gallus gallus A0A1L1RNV7 R-GGA-983700 https://reactome.org/PathwayBrowser/#/R-GGA-983700 SYK binds the activated BCR IEA Gallus gallus A0A1L1RNV7 R-GGA-983703 https://reactome.org/PathwayBrowser/#/R-GGA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Gallus gallus A0A1L1RNV7 R-GGA-983707 https://reactome.org/PathwayBrowser/#/R-GGA-983707 SYK autophosphorylates at the activated BCR IEA Gallus gallus A0A1L1RNY8 R-GGA-212222 https://reactome.org/PathwayBrowser/#/R-GGA-212222 PRC2 recruits DNA methyltransferases IEA Gallus gallus A0A1L1RNY8 R-GGA-212252 https://reactome.org/PathwayBrowser/#/R-GGA-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Gallus gallus A0A1L1RNY8 R-GGA-212263 https://reactome.org/PathwayBrowser/#/R-GGA-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Gallus gallus A0A1L1RNY8 R-GGA-212269 https://reactome.org/PathwayBrowser/#/R-GGA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Gallus gallus A0A1L1RNY8 R-GGA-2172678 https://reactome.org/PathwayBrowser/#/R-GGA-2172678 PHF8 demethylates histone H4K20me1 IEA Gallus gallus A0A1L1RNY8 R-GGA-2288097 https://reactome.org/PathwayBrowser/#/R-GGA-2288097 Condensin II complex binds H4K20me1-containing nucleosomes IEA Gallus gallus A0A1L1RNY8 R-GGA-2294580 https://reactome.org/PathwayBrowser/#/R-GGA-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Gallus gallus A0A1L1RNY8 R-GGA-2294590 https://reactome.org/PathwayBrowser/#/R-GGA-2294590 PLK1 binds phosphorylated condensin II complex IEA Gallus gallus A0A1L1RNY8 R-GGA-2301205 https://reactome.org/PathwayBrowser/#/R-GGA-2301205 SETD8 monomethylates histone H4 IEA Gallus gallus A0A1L1RNY8 R-GGA-3229089 https://reactome.org/PathwayBrowser/#/R-GGA-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Gallus gallus A0A1L1RNY8 R-GGA-3229102 https://reactome.org/PathwayBrowser/#/R-GGA-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Gallus gallus A0A1L1RNY8 R-GGA-3240295 https://reactome.org/PathwayBrowser/#/R-GGA-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Gallus gallus A0A1L1RNY8 R-GGA-3364026 https://reactome.org/PathwayBrowser/#/R-GGA-3364026 SET1 complex trimethylates H3K4 at the MYC gene IEA Gallus gallus A0A1L1RNY8 R-GGA-3662335 https://reactome.org/PathwayBrowser/#/R-GGA-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Gallus gallus A0A1L1RNY8 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus A0A1L1RNY8 R-GGA-3777129 https://reactome.org/PathwayBrowser/#/R-GGA-3777129 HDAC3 containing complexes deacetylate histone IEA Gallus gallus A0A1L1RNY8 R-GGA-3782637 https://reactome.org/PathwayBrowser/#/R-GGA-3782637 HDAC8 deacetylates histones IEA Gallus gallus A0A1L1RNY8 R-GGA-3782655 https://reactome.org/PathwayBrowser/#/R-GGA-3782655 HDAC10 deacetylates histone IEA Gallus gallus A0A1L1RNY8 R-GGA-5250938 https://reactome.org/PathwayBrowser/#/R-GGA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Gallus gallus A0A1L1RNY8 R-GGA-5578742 https://reactome.org/PathwayBrowser/#/R-GGA-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Gallus gallus A0A1L1RNY8 R-GGA-5625784 https://reactome.org/PathwayBrowser/#/R-GGA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Gallus gallus A0A1L1RNY8 R-GGA-5625796 https://reactome.org/PathwayBrowser/#/R-GGA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Gallus gallus A0A1L1RNY8 R-GGA-5625797 https://reactome.org/PathwayBrowser/#/R-GGA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Gallus gallus A0A1L1RNY8 R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus A0A1L1RNY8 R-GGA-5625849 https://reactome.org/PathwayBrowser/#/R-GGA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Gallus gallus A0A1L1RNY8 R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus A0A1L1RNY8 R-GGA-5682586 https://reactome.org/PathwayBrowser/#/R-GGA-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Gallus gallus A0A1L1RNY8 R-GGA-5682588 https://reactome.org/PathwayBrowser/#/R-GGA-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Gallus gallus A0A1L1RNY8 R-GGA-5682598 https://reactome.org/PathwayBrowser/#/R-GGA-5682598 ATM phosphorylates HERC2 IEA Gallus gallus A0A1L1RNY8 R-GGA-5682607 https://reactome.org/PathwayBrowser/#/R-GGA-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Gallus gallus A0A1L1RNY8 R-GGA-5682629 https://reactome.org/PathwayBrowser/#/R-GGA-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Gallus gallus A0A1L1RNY8 R-GGA-5682858 https://reactome.org/PathwayBrowser/#/R-GGA-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Gallus gallus A0A1L1RNY8 R-GGA-5682863 https://reactome.org/PathwayBrowser/#/R-GGA-5682863 RNF168 binds DNA DSBs IEA Gallus gallus A0A1L1RNY8 R-GGA-5682965 https://reactome.org/PathwayBrowser/#/R-GGA-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Gallus gallus A0A1L1RNY8 R-GGA-5682967 https://reactome.org/PathwayBrowser/#/R-GGA-5682967 WHSC1 binds DNA DSBs IEA Gallus gallus A0A1L1RNY8 R-GGA-5682983 https://reactome.org/PathwayBrowser/#/R-GGA-5682983 ATM phosphorylates WHSC1 IEA Gallus gallus A0A1L1RNY8 R-GGA-5682992 https://reactome.org/PathwayBrowser/#/R-GGA-5682992 KDM4A,B bind H4K20Me2 IEA Gallus gallus A0A1L1RNY8 R-GGA-5683077 https://reactome.org/PathwayBrowser/#/R-GGA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Gallus gallus A0A1L1RNY8 R-GGA-5683384 https://reactome.org/PathwayBrowser/#/R-GGA-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Gallus gallus A0A1L1RNY8 R-GGA-5683385 https://reactome.org/PathwayBrowser/#/R-GGA-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Gallus gallus A0A1L1RNY8 R-GGA-5683425 https://reactome.org/PathwayBrowser/#/R-GGA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Gallus gallus A0A1L1RNY8 R-GGA-5683735 https://reactome.org/PathwayBrowser/#/R-GGA-5683735 CHEK2 is recruited to DNA DSBs IEA Gallus gallus A0A1L1RNY8 R-GGA-5683801 https://reactome.org/PathwayBrowser/#/R-GGA-5683801 CHEK2 phosphorylates BRCA1 IEA Gallus gallus A0A1L1RNY8 R-GGA-5683930 https://reactome.org/PathwayBrowser/#/R-GGA-5683930 WICH phosphorylates H2AFX on Y142 IEA Gallus gallus A0A1L1RNY8 R-GGA-5683964 https://reactome.org/PathwayBrowser/#/R-GGA-5683964 ATM phosphorylates EYA1-4 IEA Gallus gallus A0A1L1RNY8 R-GGA-5683967 https://reactome.org/PathwayBrowser/#/R-GGA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Gallus gallus A0A1L1RNY8 R-GGA-5683986 https://reactome.org/PathwayBrowser/#/R-GGA-5683986 APBB1 and MAPK8 bind diphosphorylated H2AFX IEA Gallus gallus A0A1L1RNY8 R-GGA-5684052 https://reactome.org/PathwayBrowser/#/R-GGA-5684052 PIAS4 SUMOylates MDC1 IEA Gallus gallus A0A1L1RNY8 R-GGA-5686685 https://reactome.org/PathwayBrowser/#/R-GGA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Gallus gallus A0A1L1RNY8 R-GGA-5686704 https://reactome.org/PathwayBrowser/#/R-GGA-5686704 Activated ATM phosphorylates DCLRE1C IEA Gallus gallus A0A1L1RNY8 R-GGA-5686900 https://reactome.org/PathwayBrowser/#/R-GGA-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Gallus gallus A0A1L1RNY8 R-GGA-5690157 https://reactome.org/PathwayBrowser/#/R-GGA-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Gallus gallus A0A1L1RNY8 R-GGA-5690790 https://reactome.org/PathwayBrowser/#/R-GGA-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Gallus gallus A0A1L1RNY8 R-GGA-5691381 https://reactome.org/PathwayBrowser/#/R-GGA-5691381 MYSM1 deubiquitinates Histone H2A IEA Gallus gallus A0A1L1RNY8 R-GGA-5691411 https://reactome.org/PathwayBrowser/#/R-GGA-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Gallus gallus A0A1L1RNY8 R-GGA-5693536 https://reactome.org/PathwayBrowser/#/R-GGA-5693536 ATM phosphorylates MDC1 IEA Gallus gallus A0A1L1RNY8 R-GGA-5693549 https://reactome.org/PathwayBrowser/#/R-GGA-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Gallus gallus A0A1L1RNY8 R-GGA-5693551 https://reactome.org/PathwayBrowser/#/R-GGA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Gallus gallus A0A1L1RNY8 R-GGA-5693566 https://reactome.org/PathwayBrowser/#/R-GGA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Gallus gallus A0A1L1RNY8 R-GGA-5693602 https://reactome.org/PathwayBrowser/#/R-GGA-5693602 ATM recognizes H2AFX-Nucleosomes IEA Gallus gallus A0A1L1RNY8 R-GGA-606287 https://reactome.org/PathwayBrowser/#/R-GGA-606287 RSF complex binds the centromere IEA Gallus gallus A0A1L1RNY8 R-GGA-606289 https://reactome.org/PathwayBrowser/#/R-GGA-606289 New CENPA-containing nucleosomes are deposited at the centromere IEA Gallus gallus A0A1L1RNY8 R-GGA-69891 https://reactome.org/PathwayBrowser/#/R-GGA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Gallus gallus A0A1L1RNY8 R-GGA-73718 https://reactome.org/PathwayBrowser/#/R-GGA-73718 UBF-1 Binds rDNA Promoter IEA Gallus gallus A0A1L1RNY8 R-GGA-74986 https://reactome.org/PathwayBrowser/#/R-GGA-74986 Elongation of pre-rRNA transcript IEA Gallus gallus A0A1L1RNY8 R-GGA-8936481 https://reactome.org/PathwayBrowser/#/R-GGA-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Gallus gallus A0A1L1RNY8 R-GGA-8936584 https://reactome.org/PathwayBrowser/#/R-GGA-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Gallus gallus A0A1L1RNY8 R-GGA-8936608 https://reactome.org/PathwayBrowser/#/R-GGA-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Gallus gallus A0A1L1RNY8 R-GGA-8936621 https://reactome.org/PathwayBrowser/#/R-GGA-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Gallus gallus A0A1L1RNY8 R-GGA-8937016 https://reactome.org/PathwayBrowser/#/R-GGA-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Gallus gallus A0A1L1RNY8 R-GGA-8937022 https://reactome.org/PathwayBrowser/#/R-GGA-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Gallus gallus A0A1L1RNY8 R-GGA-8937050 https://reactome.org/PathwayBrowser/#/R-GGA-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Gallus gallus A0A1L1RNY8 R-GGA-8937113 https://reactome.org/PathwayBrowser/#/R-GGA-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Gallus gallus A0A1L1RNY8 R-GGA-9009065 https://reactome.org/PathwayBrowser/#/R-GGA-9009065 FOXA1 and GATA3 bind to CCND1 promoter IEA Gallus gallus A0A1L1RNY8 R-GGA-9009371 https://reactome.org/PathwayBrowser/#/R-GGA-9009371 Binding of AP1 transcriptional activator complexes to CCND1 promoter IEA Gallus gallus A0A1L1RNY8 R-GGA-9011949 https://reactome.org/PathwayBrowser/#/R-GGA-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Gallus gallus A0A1L1RNY8 R-GGA-9011952 https://reactome.org/PathwayBrowser/#/R-GGA-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Gallus gallus A0A1L1RNY8 R-GGA-9011983 https://reactome.org/PathwayBrowser/#/R-GGA-9011983 Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes IEA Gallus gallus A0A1L1RNY8 R-GGA-9012000 https://reactome.org/PathwayBrowser/#/R-GGA-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Gallus gallus A0A1L1RNY8 R-GGA-9749197 https://reactome.org/PathwayBrowser/#/R-GGA-9749197 ORC1 binds to H4K20me2 IEA Gallus gallus A0A1L1RNY8 R-GGA-9842833 https://reactome.org/PathwayBrowser/#/R-GGA-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Gallus gallus A0A1L1RNY8 R-GGA-9842835 https://reactome.org/PathwayBrowser/#/R-GGA-9842835 KRAB-ZFP binds retroelement DNA in chromatin IEA Gallus gallus A0A1L1RNY8 R-GGA-9842839 https://reactome.org/PathwayBrowser/#/R-GGA-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1L1RNY8 R-GGA-9843115 https://reactome.org/PathwayBrowser/#/R-GGA-9843115 Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci IEA Gallus gallus A0A1L1RNY8 R-GGA-9843117 https://reactome.org/PathwayBrowser/#/R-GGA-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1L1RNY8 R-GGA-9843118 https://reactome.org/PathwayBrowser/#/R-GGA-9843118 RXRA binds ligands IEA Gallus gallus A0A1L1RNY8 R-GGA-9843120 https://reactome.org/PathwayBrowser/#/R-GGA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Gallus gallus A0A1L1RNY8 R-GGA-9843978 https://reactome.org/PathwayBrowser/#/R-GGA-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1L1RNY8 R-GGA-9844006 https://reactome.org/PathwayBrowser/#/R-GGA-9844006 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) IEA Gallus gallus A0A1L1RNY8 R-GGA-9844015 https://reactome.org/PathwayBrowser/#/R-GGA-9844015 MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin IEA Gallus gallus A0A1L1RNY8 R-GGA-9844057 https://reactome.org/PathwayBrowser/#/R-GGA-9844057 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome IEA Gallus gallus A0A1L1RNZ0 R-GGA-350058 https://reactome.org/PathwayBrowser/#/R-GGA-350058 Formation of CSL NCOR corepressor complex IEA Gallus gallus A0A1L1RNZ2 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1L1RNZ2 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1L1RNZ2 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1L1RNZ2 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1L1RNZ2 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1L1RNZ2 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1L1RNZ2 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1L1RP17 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1L1RP32 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1L1RP52 R-GGA-114552 https://reactome.org/PathwayBrowser/#/R-GGA-114552 Thrombin-activated PARs activate G12/13 IEA Gallus gallus A0A1L1RP52 R-GGA-114558 https://reactome.org/PathwayBrowser/#/R-GGA-114558 Thrombin-activated PARs activate Gq IEA Gallus gallus A0A1L1RP52 R-GGA-114697 https://reactome.org/PathwayBrowser/#/R-GGA-114697 Activated thrombin (factor IIa) cleaves PAR3,4, activating them IEA Gallus gallus A0A1L1RP52 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus A0A1L1RP52 R-GGA-389463 https://reactome.org/PathwayBrowser/#/R-GGA-389463 Proteinase-activated receptors can bind thrombin IEA Gallus gallus A0A1L1RP52 R-GGA-396996 https://reactome.org/PathwayBrowser/#/R-GGA-396996 Thrombin-activated PARs binds G-protein Gq IEA Gallus gallus A0A1L1RP52 R-GGA-397835 https://reactome.org/PathwayBrowser/#/R-GGA-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Gallus gallus A0A1L1RP52 R-GGA-397891 https://reactome.org/PathwayBrowser/#/R-GGA-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Gallus gallus A0A1L1RP52 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus A0A1L1RP52 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus A0A1L1RPD1 R-GGA-5693742 https://reactome.org/PathwayBrowser/#/R-GGA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Gallus gallus A0A1L1RPE2 R-GGA-1112666 https://reactome.org/PathwayBrowser/#/R-GGA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Gallus gallus A0A1L1RPE2 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus A0A1L1RPE2 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus A0A1L1RPE2 R-GGA-173626 https://reactome.org/PathwayBrowser/#/R-GGA-173626 Activation of C1r IEA Gallus gallus A0A1L1RPE2 R-GGA-173631 https://reactome.org/PathwayBrowser/#/R-GGA-173631 Activation of C1s IEA Gallus gallus A0A1L1RPE2 R-GGA-1861621 https://reactome.org/PathwayBrowser/#/R-GGA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Gallus gallus A0A1L1RPE2 R-GGA-199161 https://reactome.org/PathwayBrowser/#/R-GGA-199161 Fc gamma receptors interact with antigen-bound IgG IEA Gallus gallus A0A1L1RPE2 R-GGA-2029268 https://reactome.org/PathwayBrowser/#/R-GGA-2029268 Phosphorylation and activation of PLCG IEA Gallus gallus A0A1L1RPE2 R-GGA-2029270 https://reactome.org/PathwayBrowser/#/R-GGA-2029270 Recruitment of PLCgamma to membrane IEA Gallus gallus A0A1L1RPE2 R-GGA-2029271 https://reactome.org/PathwayBrowser/#/R-GGA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1L1RPE2 R-GGA-2029272 https://reactome.org/PathwayBrowser/#/R-GGA-2029272 Release of PLCG from FCGR IEA Gallus gallus A0A1L1RPE2 R-GGA-2029273 https://reactome.org/PathwayBrowser/#/R-GGA-2029273 PI3K binds to p-6Y-SYK IEA Gallus gallus A0A1L1RPE2 R-GGA-2029451 https://reactome.org/PathwayBrowser/#/R-GGA-2029451 Activation of RAC1 by VAV IEA Gallus gallus A0A1L1RPE2 R-GGA-2029452 https://reactome.org/PathwayBrowser/#/R-GGA-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Gallus gallus A0A1L1RPE2 R-GGA-2029453 https://reactome.org/PathwayBrowser/#/R-GGA-2029453 Phosphorylation of VAV IEA Gallus gallus A0A1L1RPE2 R-GGA-2029455 https://reactome.org/PathwayBrowser/#/R-GGA-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Gallus gallus A0A1L1RPE2 R-GGA-2029457 https://reactome.org/PathwayBrowser/#/R-GGA-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Gallus gallus A0A1L1RPE2 R-GGA-2029458 https://reactome.org/PathwayBrowser/#/R-GGA-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Gallus gallus A0A1L1RPE2 R-GGA-2029459 https://reactome.org/PathwayBrowser/#/R-GGA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Gallus gallus A0A1L1RPE2 R-GGA-2029467 https://reactome.org/PathwayBrowser/#/R-GGA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Gallus gallus A0A1L1RPE2 R-GGA-2029476 https://reactome.org/PathwayBrowser/#/R-GGA-2029476 Role of myosins in phagosome formation IEA Gallus gallus A0A1L1RPE2 R-GGA-2197697 https://reactome.org/PathwayBrowser/#/R-GGA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Gallus gallus A0A1L1RPE2 R-GGA-2203516 https://reactome.org/PathwayBrowser/#/R-GGA-2203516 Alpha-1-Microglobulin is cleaved IEA Gallus gallus A0A1L1RPE2 R-GGA-8852266 https://reactome.org/PathwayBrowser/#/R-GGA-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Gallus gallus A0A1L1RPE2 R-GGA-8852481 https://reactome.org/PathwayBrowser/#/R-GGA-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Gallus gallus A0A1L1RPE2 R-GGA-8858428 https://reactome.org/PathwayBrowser/#/R-GGA-8858428 FCAMR binds IgA IEA Gallus gallus A0A1L1RPE2 R-GGA-9021306 https://reactome.org/PathwayBrowser/#/R-GGA-9021306 C1-Inh binds and inactivates C1r, C1s IEA Gallus gallus A0A1L1RPE2 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus A0A1L1RPE2 R-GGA-9724685 https://reactome.org/PathwayBrowser/#/R-GGA-9724685 IgE binds omalizumab IEA Gallus gallus A0A1L1RPE2 R-GGA-983696 https://reactome.org/PathwayBrowser/#/R-GGA-983696 The Immunoglobulin of the BCR binds antigen IEA Gallus gallus A0A1L1RPE2 R-GGA-983700 https://reactome.org/PathwayBrowser/#/R-GGA-983700 SYK binds the activated BCR IEA Gallus gallus A0A1L1RPE2 R-GGA-983703 https://reactome.org/PathwayBrowser/#/R-GGA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Gallus gallus A0A1L1RPE2 R-GGA-983707 https://reactome.org/PathwayBrowser/#/R-GGA-983707 SYK autophosphorylates at the activated BCR IEA Gallus gallus A0A1L1RPH5 R-GGA-373745 https://reactome.org/PathwayBrowser/#/R-GGA-373745 SDK1 homophillic interaction IEA Gallus gallus A0A1L1RPI2 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1L1RPI2 R-GGA-9842833 https://reactome.org/PathwayBrowser/#/R-GGA-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Gallus gallus A0A1L1RPI2 R-GGA-9842835 https://reactome.org/PathwayBrowser/#/R-GGA-9842835 KRAB-ZFP binds retroelement DNA in chromatin IEA Gallus gallus A0A1L1RPI2 R-GGA-9842839 https://reactome.org/PathwayBrowser/#/R-GGA-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1L1RPI2 R-GGA-9843978 https://reactome.org/PathwayBrowser/#/R-GGA-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1L1RPJ4 R-GGA-8952618 https://reactome.org/PathwayBrowser/#/R-GGA-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1L1RPJ4 R-GGA-8952620 https://reactome.org/PathwayBrowser/#/R-GGA-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1L1RPJ4 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1L1RPJ4 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1L1RPJ4 R-GGA-8956200 https://reactome.org/PathwayBrowser/#/R-GGA-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1L1RPJ4 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1L1RPJ4 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1L1RPJ4 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1L1RPJ4 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1L1RPK0 R-GGA-109639 https://reactome.org/PathwayBrowser/#/R-GGA-109639 Formation of the closed pre-initiation complex IEA Gallus gallus A0A1L1RPK0 R-GGA-111264 https://reactome.org/PathwayBrowser/#/R-GGA-111264 Addition of nucleotides between position +11 and +30 IEA Gallus gallus A0A1L1RPK0 R-GGA-112383 https://reactome.org/PathwayBrowser/#/R-GGA-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Gallus gallus A0A1L1RPK0 R-GGA-112385 https://reactome.org/PathwayBrowser/#/R-GGA-112385 Addition of nucleotides leads to transcript elongation IEA Gallus gallus A0A1L1RPK0 R-GGA-113430 https://reactome.org/PathwayBrowser/#/R-GGA-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Gallus gallus A0A1L1RPK0 R-GGA-170087 https://reactome.org/PathwayBrowser/#/R-GGA-170087 CAK phosphorylates CDK1 bound to CCNA IEA Gallus gallus A0A1L1RPK0 R-GGA-187949 https://reactome.org/PathwayBrowser/#/R-GGA-187949 CAK-mediated phosphorylation of Cyclin A:Cdk2 IEA Gallus gallus A0A1L1RPK0 R-GGA-188350 https://reactome.org/PathwayBrowser/#/R-GGA-188350 CAK-mediated phosphorylation of Cyclin E:Cdk2 IEA Gallus gallus A0A1L1RPK0 R-GGA-5689861 https://reactome.org/PathwayBrowser/#/R-GGA-5689861 Recruitment of XPA and release of CAK IEA Gallus gallus A0A1L1RPK0 R-GGA-5691000 https://reactome.org/PathwayBrowser/#/R-GGA-5691000 TFIIH binds GG-NER site to form a verification complex IEA Gallus gallus A0A1L1RPK0 R-GGA-6781818 https://reactome.org/PathwayBrowser/#/R-GGA-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Gallus gallus A0A1L1RPK0 R-GGA-6781824 https://reactome.org/PathwayBrowser/#/R-GGA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Gallus gallus A0A1L1RPK0 R-GGA-6781833 https://reactome.org/PathwayBrowser/#/R-GGA-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Gallus gallus A0A1L1RPK0 R-GGA-6781840 https://reactome.org/PathwayBrowser/#/R-GGA-6781840 ERCC6 binds stalled RNA Pol II IEA Gallus gallus A0A1L1RPK0 R-GGA-6781867 https://reactome.org/PathwayBrowser/#/R-GGA-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Gallus gallus A0A1L1RPK0 R-GGA-6782069 https://reactome.org/PathwayBrowser/#/R-GGA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Gallus gallus A0A1L1RPK0 R-GGA-6782131 https://reactome.org/PathwayBrowser/#/R-GGA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1L1RPK0 R-GGA-6782138 https://reactome.org/PathwayBrowser/#/R-GGA-6782138 ERCC5 and RPA bind TC-NER site IEA Gallus gallus A0A1L1RPK0 R-GGA-6782204 https://reactome.org/PathwayBrowser/#/R-GGA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Gallus gallus A0A1L1RPK0 R-GGA-6782208 https://reactome.org/PathwayBrowser/#/R-GGA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Gallus gallus A0A1L1RPK0 R-GGA-6782211 https://reactome.org/PathwayBrowser/#/R-GGA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Gallus gallus A0A1L1RPK0 R-GGA-6782227 https://reactome.org/PathwayBrowser/#/R-GGA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Gallus gallus A0A1L1RPK0 R-GGA-6797606 https://reactome.org/PathwayBrowser/#/R-GGA-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Gallus gallus A0A1L1RPK0 R-GGA-6797616 https://reactome.org/PathwayBrowser/#/R-GGA-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Gallus gallus A0A1L1RPK0 R-GGA-73758 https://reactome.org/PathwayBrowser/#/R-GGA-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Gallus gallus A0A1L1RPK0 R-GGA-73769 https://reactome.org/PathwayBrowser/#/R-GGA-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Gallus gallus A0A1L1RPK0 R-GGA-73946 https://reactome.org/PathwayBrowser/#/R-GGA-73946 Abortive initiation after formation of the first phosphodiester bond IEA Gallus gallus A0A1L1RPK0 R-GGA-74986 https://reactome.org/PathwayBrowser/#/R-GGA-74986 Elongation of pre-rRNA transcript IEA Gallus gallus A0A1L1RPK0 R-GGA-74993 https://reactome.org/PathwayBrowser/#/R-GGA-74993 PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box IEA Gallus gallus A0A1L1RPK0 R-GGA-75850 https://reactome.org/PathwayBrowser/#/R-GGA-75850 Addition of the third nucleotide on the nascent transcript IEA Gallus gallus A0A1L1RPK0 R-GGA-75856 https://reactome.org/PathwayBrowser/#/R-GGA-75856 Abortive Initiation Before Second Transition IEA Gallus gallus A0A1L1RPK0 R-GGA-75861 https://reactome.org/PathwayBrowser/#/R-GGA-75861 NTP Binds Active Site of RNA Polymerase II IEA Gallus gallus A0A1L1RPK0 R-GGA-75862 https://reactome.org/PathwayBrowser/#/R-GGA-75862 Fall Back to Closed Pre-initiation Complex IEA Gallus gallus A0A1L1RPK0 R-GGA-75864 https://reactome.org/PathwayBrowser/#/R-GGA-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Gallus gallus A0A1L1RPK0 R-GGA-75866 https://reactome.org/PathwayBrowser/#/R-GGA-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Gallus gallus A0A1L1RPK0 R-GGA-75869 https://reactome.org/PathwayBrowser/#/R-GGA-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Gallus gallus A0A1L1RPK0 R-GGA-75873 https://reactome.org/PathwayBrowser/#/R-GGA-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Gallus gallus A0A1L1RPK0 R-GGA-75891 https://reactome.org/PathwayBrowser/#/R-GGA-75891 Abortive Initiation After Second Transition IEA Gallus gallus A0A1L1RPK0 R-GGA-75949 https://reactome.org/PathwayBrowser/#/R-GGA-75949 RNA Polymerase II Promoter Opening: First Transition IEA Gallus gallus A0A1L1RPK0 R-GGA-76576 https://reactome.org/PathwayBrowser/#/R-GGA-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Gallus gallus A0A1L1RPK0 R-GGA-77068 https://reactome.org/PathwayBrowser/#/R-GGA-77068 Activation of GT IEA Gallus gallus A0A1L1RPK0 R-GGA-77069 https://reactome.org/PathwayBrowser/#/R-GGA-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Gallus gallus A0A1L1RPK0 R-GGA-77071 https://reactome.org/PathwayBrowser/#/R-GGA-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Gallus gallus A0A1L1RPK0 R-GGA-77077 https://reactome.org/PathwayBrowser/#/R-GGA-77077 Capping complex formation IEA Gallus gallus A0A1L1RPK0 R-GGA-77078 https://reactome.org/PathwayBrowser/#/R-GGA-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Gallus gallus A0A1L1RPK0 R-GGA-77081 https://reactome.org/PathwayBrowser/#/R-GGA-77081 Formation of the CE:GMP intermediate complex IEA Gallus gallus A0A1L1RPK0 R-GGA-77083 https://reactome.org/PathwayBrowser/#/R-GGA-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Gallus gallus A0A1L1RPK0 R-GGA-77085 https://reactome.org/PathwayBrowser/#/R-GGA-77085 Dissociation of transcript with 5'-GMP from GT IEA Gallus gallus A0A1L1RPK0 R-GGA-8942836 https://reactome.org/PathwayBrowser/#/R-GGA-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Gallus gallus A0A1L1RPK0 R-GGA-8956568 https://reactome.org/PathwayBrowser/#/R-GGA-8956568 RUNX1 binds the core TAL1 complex IEA Gallus gallus A0A1L1RPK0 R-GGA-9613494 https://reactome.org/PathwayBrowser/#/R-GGA-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Gallus gallus A0A1L1RPK0 R-GGA-9613497 https://reactome.org/PathwayBrowser/#/R-GGA-9613497 Unwinding DNA for the nascent transcript IEA Gallus gallus A0A1L1RPK0 R-GGA-9684118 https://reactome.org/PathwayBrowser/#/R-GGA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Gallus gallus A0A1L1RPL5 R-GGA-8869607 https://reactome.org/PathwayBrowser/#/R-GGA-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Gallus gallus A0A1L1RPL5 R-GGA-8869627 https://reactome.org/PathwayBrowser/#/R-GGA-8869627 NMRK2 phosphorylates NR to yield NMN IEA Gallus gallus A0A1L1RPL6 R-GGA-77319 https://reactome.org/PathwayBrowser/#/R-GGA-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Gallus gallus A0A1L1RPL6 R-GGA-77327 https://reactome.org/PathwayBrowser/#/R-GGA-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Gallus gallus A0A1L1RPM7 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1L1RPR4 R-GGA-6784393 https://reactome.org/PathwayBrowser/#/R-GGA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) IEA Gallus gallus A0A1L1RPR4 R-GGA-70596 https://reactome.org/PathwayBrowser/#/R-GGA-70596 GOT2 dimer transaminates L-Asp IEA Gallus gallus A0A1L1RPR4 R-GGA-70613 https://reactome.org/PathwayBrowser/#/R-GGA-70613 GOT2 transaminates OA and L-Glu IEA Gallus gallus A0A1L1RPU5 R-GGA-201510 https://reactome.org/PathwayBrowser/#/R-GGA-201510 PI3K synthesizes PIP3 downstream of ALK IEA Gallus gallus A0A1L1RPU5 R-GGA-201515 https://reactome.org/PathwayBrowser/#/R-GGA-201515 Active ALK recruits PI3K IEA Gallus gallus A0A1L1RPU5 R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus A0A1L1RPU5 R-GGA-2974737 https://reactome.org/PathwayBrowser/#/R-GGA-2974737 NOTCH2 binds MDK IEA Gallus gallus A0A1L1RPU5 R-GGA-9667914 https://reactome.org/PathwayBrowser/#/R-GGA-9667914 ALK binds ligand midkine (MDK) IEA Gallus gallus A0A1L1RPU5 R-GGA-9700120 https://reactome.org/PathwayBrowser/#/R-GGA-9700120 PTN and MDK bind to PTPRZ IEA Gallus gallus A0A1L1RPU5 R-GGA-9700121 https://reactome.org/PathwayBrowser/#/R-GGA-9700121 (PTN,MDK):PTPRZ oligomerizes IEA Gallus gallus A0A1L1RPU5 R-GGA-9700149 https://reactome.org/PathwayBrowser/#/R-GGA-9700149 Active ALK binds PLCG1 IEA Gallus gallus A0A1L1RPU5 R-GGA-9700154 https://reactome.org/PathwayBrowser/#/R-GGA-9700154 Active ALK binds SHC1 IEA Gallus gallus A0A1L1RPU5 R-GGA-9700156 https://reactome.org/PathwayBrowser/#/R-GGA-9700156 Active ALK dimer binds IRS1 IEA Gallus gallus A0A1L1RPU5 R-GGA-9700168 https://reactome.org/PathwayBrowser/#/R-GGA-9700168 Active ALK phosphorylates IRS1 IEA Gallus gallus A0A1L1RPU5 R-GGA-9700171 https://reactome.org/PathwayBrowser/#/R-GGA-9700171 Active ALK phosphorylates PLCG1 IEA Gallus gallus A0A1L1RPU5 R-GGA-9700175 https://reactome.org/PathwayBrowser/#/R-GGA-9700175 Active ALK phosphorylates SHC1 IEA Gallus gallus A0A1L1RPU5 R-GGA-9700200 https://reactome.org/PathwayBrowser/#/R-GGA-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Gallus gallus A0A1L1RPU5 R-GGA-9700662 https://reactome.org/PathwayBrowser/#/R-GGA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Gallus gallus A0A1L1RPU5 R-GGA-9701524 https://reactome.org/PathwayBrowser/#/R-GGA-9701524 STAT3 is phosphorylated downstream of active ALK IEA Gallus gallus A0A1L1RPW4 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus A0A1L1RPW4 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus A0A1L1RPW4 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus A0A1L1RPW4 R-GGA-1981120 https://reactome.org/PathwayBrowser/#/R-GGA-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Gallus gallus A0A1L1RPW4 R-GGA-2002460 https://reactome.org/PathwayBrowser/#/R-GGA-2002460 P4HB binds Collagen chains IEA Gallus gallus A0A1L1RPW4 R-GGA-2089971 https://reactome.org/PathwayBrowser/#/R-GGA-2089971 Secretion of collagens IEA Gallus gallus A0A1L1RPW4 R-GGA-2168046 https://reactome.org/PathwayBrowser/#/R-GGA-2168046 Collagen type XII degradation by MMP12 IEA Gallus gallus A0A1L1RPW4 R-GGA-2213205 https://reactome.org/PathwayBrowser/#/R-GGA-2213205 Type XII and XIV collagens associate with type I and type II fibrils IEA Gallus gallus A0A1L1RPW4 R-GGA-8944227 https://reactome.org/PathwayBrowser/#/R-GGA-8944227 Association of procollagen type XXII IEA Gallus gallus A0A1L1RPW4 R-GGA-8944232 https://reactome.org/PathwayBrowser/#/R-GGA-8944232 Association of procollagen type XII IEA Gallus gallus A0A1L1RPW4 R-GGA-8948228 https://reactome.org/PathwayBrowser/#/R-GGA-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Gallus gallus A0A1L1RPW4 R-GGA-8948231 https://reactome.org/PathwayBrowser/#/R-GGA-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Gallus gallus A0A1L1RPW4 R-GGA-8948232 https://reactome.org/PathwayBrowser/#/R-GGA-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Gallus gallus A0A1L1RPW4 R-GGA-8948234 https://reactome.org/PathwayBrowser/#/R-GGA-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Gallus gallus A0A1L1RPW8 R-GGA-8851396 https://reactome.org/PathwayBrowser/#/R-GGA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Gallus gallus A0A1L1RPX5 R-GGA-5693783 https://reactome.org/PathwayBrowser/#/R-GGA-5693783 NAALADases hydrolyse NAAG IEA Gallus gallus A0A1L1RQ52 R-GGA-6789310 https://reactome.org/PathwayBrowser/#/R-GGA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Gallus gallus A0A1L1RQ91 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1L1RQ91 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1L1RQ91 R-GGA-70471 https://reactome.org/PathwayBrowser/#/R-GGA-70471 GPI dimer isomerizes G6P IEA Gallus gallus A0A1L1RQ91 R-GGA-70475 https://reactome.org/PathwayBrowser/#/R-GGA-70475 GPI dimer isomerizes Fru(6)P to G6P IEA Gallus gallus A0A1L1RQ94 R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus A0A1L1RQ94 R-GGA-9709406 https://reactome.org/PathwayBrowser/#/R-GGA-9709406 CO binds to Cytochrome c oxidase IEA Gallus gallus A0A1L1RQA3 R-GGA-425678 https://reactome.org/PathwayBrowser/#/R-GGA-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Gallus gallus A0A1L1RQB9 R-GGA-6789310 https://reactome.org/PathwayBrowser/#/R-GGA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Gallus gallus A0A1L1RQG8 R-GGA-8870457 https://reactome.org/PathwayBrowser/#/R-GGA-8870457 FarC-PTP4A2 binds RABGGTB IEA Gallus gallus A0A1L1RQI4 R-GGA-1878002 https://reactome.org/PathwayBrowser/#/R-GGA-1878002 XYLTs transfer Xyl to core protein IEA Gallus gallus A0A1L1RQI4 R-GGA-1889955 https://reactome.org/PathwayBrowser/#/R-GGA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Gallus gallus A0A1L1RQI4 R-GGA-1889981 https://reactome.org/PathwayBrowser/#/R-GGA-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Gallus gallus A0A1L1RQI4 R-GGA-1971482 https://reactome.org/PathwayBrowser/#/R-GGA-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Gallus gallus A0A1L1RQI4 R-GGA-1971483 https://reactome.org/PathwayBrowser/#/R-GGA-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Gallus gallus A0A1L1RQI4 R-GGA-1971487 https://reactome.org/PathwayBrowser/#/R-GGA-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Gallus gallus A0A1L1RQI4 R-GGA-1971491 https://reactome.org/PathwayBrowser/#/R-GGA-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Gallus gallus A0A1L1RQI4 R-GGA-2018659 https://reactome.org/PathwayBrowser/#/R-GGA-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Gallus gallus A0A1L1RQI4 R-GGA-2018682 https://reactome.org/PathwayBrowser/#/R-GGA-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Gallus gallus A0A1L1RQI4 R-GGA-2022052 https://reactome.org/PathwayBrowser/#/R-GGA-2022052 Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS) IEA Gallus gallus A0A1L1RQI4 R-GGA-2022056 https://reactome.org/PathwayBrowser/#/R-GGA-2022056 DSPG and CSPG translocate to the lysosome for degradation IEA Gallus gallus A0A1L1RQI4 R-GGA-2022061 https://reactome.org/PathwayBrowser/#/R-GGA-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Gallus gallus A0A1L1RQI4 R-GGA-2022063 https://reactome.org/PathwayBrowser/#/R-GGA-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Gallus gallus A0A1L1RQI4 R-GGA-2022065 https://reactome.org/PathwayBrowser/#/R-GGA-2022065 DSPGs are secreted IEA Gallus gallus A0A1L1RQI4 R-GGA-2022911 https://reactome.org/PathwayBrowser/#/R-GGA-2022911 CSPG is secreted IEA Gallus gallus A0A1L1RQI4 R-GGA-2424246 https://reactome.org/PathwayBrowser/#/R-GGA-2424246 Tenascins C, R, (X, N) bind lecticans IEA Gallus gallus A0A1L1RQI4 R-GGA-3788075 https://reactome.org/PathwayBrowser/#/R-GGA-3788075 Brevican degradation by ADAMTS4, ADAMTS5 IEA Gallus gallus A0A1L1RQI4 R-GGA-3791149 https://reactome.org/PathwayBrowser/#/R-GGA-3791149 Brevican degradation by MMP1, 2, 3, 7,8,10,13,19 IEA Gallus gallus A0A1L1RQI4 R-GGA-9632033 https://reactome.org/PathwayBrowser/#/R-GGA-9632033 CHSY1 transfers GalNAc to chondroitin IEA Gallus gallus A0A1L1RQI4 R-GGA-9632034 https://reactome.org/PathwayBrowser/#/R-GGA-9632034 CHSY1 transfers GlcA to chondroitin IEA Gallus gallus A0A1L1RQJ9 R-GGA-392051 https://reactome.org/PathwayBrowser/#/R-GGA-392051 Recruitment of Grb2 to pFAK:NCAM1 IEA Gallus gallus A0A1L1RQJ9 R-GGA-392053 https://reactome.org/PathwayBrowser/#/R-GGA-392053 SOS binds Grb2 bound to pFAK:NCAM1 IEA Gallus gallus A0A1L1RQJ9 R-GGA-392054 https://reactome.org/PathwayBrowser/#/R-GGA-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Gallus gallus A0A1L1RQJ9 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1L1RQJ9 R-GGA-6807877 https://reactome.org/PathwayBrowser/#/R-GGA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Gallus gallus A0A1L1RQJ9 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1L1RQJ9 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1L1RQJ9 R-GGA-6809011 https://reactome.org/PathwayBrowser/#/R-GGA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Gallus gallus A0A1L1RQM9 R-GGA-111439 https://reactome.org/PathwayBrowser/#/R-GGA-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Gallus gallus A0A1L1RQM9 R-GGA-158441 https://reactome.org/PathwayBrowser/#/R-GGA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1L1RQM9 R-GGA-158447 https://reactome.org/PathwayBrowser/#/R-GGA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Gallus gallus A0A1L1RQM9 R-GGA-158481 https://reactome.org/PathwayBrowser/#/R-GGA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Gallus gallus A0A1L1RQM9 R-GGA-158484 https://reactome.org/PathwayBrowser/#/R-GGA-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Gallus gallus A0A1L1RQM9 R-GGA-159046 https://reactome.org/PathwayBrowser/#/R-GGA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Gallus gallus A0A1L1RQM9 R-GGA-159050 https://reactome.org/PathwayBrowser/#/R-GGA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Gallus gallus A0A1L1RQM9 R-GGA-170825 https://reactome.org/PathwayBrowser/#/R-GGA-170825 NPC exports GCK1 from nucleus IEA Gallus gallus A0A1L1RQM9 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1L1RQM9 R-GGA-2990880 https://reactome.org/PathwayBrowser/#/R-GGA-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Gallus gallus A0A1L1RQM9 R-GGA-2990882 https://reactome.org/PathwayBrowser/#/R-GGA-2990882 CDK1 phosphorylates NUP98 IEA Gallus gallus A0A1L1RQM9 R-GGA-4551649 https://reactome.org/PathwayBrowser/#/R-GGA-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Gallus gallus A0A1L1RQM9 R-GGA-4551679 https://reactome.org/PathwayBrowser/#/R-GGA-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Gallus gallus A0A1L1RQM9 R-GGA-4615872 https://reactome.org/PathwayBrowser/#/R-GGA-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Gallus gallus A0A1L1RQM9 R-GGA-4615987 https://reactome.org/PathwayBrowser/#/R-GGA-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Gallus gallus A0A1L1RQM9 R-GGA-4655355 https://reactome.org/PathwayBrowser/#/R-GGA-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Gallus gallus A0A1L1RQM9 R-GGA-5228523 https://reactome.org/PathwayBrowser/#/R-GGA-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Gallus gallus A0A1L1RQM9 R-GGA-5578744 https://reactome.org/PathwayBrowser/#/R-GGA-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Gallus gallus A0A1L1RQM9 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1L1RQM9 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1L1RQM9 R-GGA-77587 https://reactome.org/PathwayBrowser/#/R-GGA-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Gallus gallus A0A1L1RQM9 R-GGA-9013009 https://reactome.org/PathwayBrowser/#/R-GGA-9013009 RHOA binds effectors at the plasma membrane IEA Gallus gallus A0A1L1RQQ1 R-GGA-6806966 https://reactome.org/PathwayBrowser/#/R-GGA-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX IEA Gallus gallus A0A1L1RQR5 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1L1RQR5 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1L1RQR5 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1L1RQR5 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1L1RQR5 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1L1RQR5 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1L1RQR5 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1L1RQU5 R-GGA-8938076 https://reactome.org/PathwayBrowser/#/R-GGA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Gallus gallus A0A1L1RQU7 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1L1RQY7 R-GGA-8863463 https://reactome.org/PathwayBrowser/#/R-GGA-8863463 STON2 binds SYT proteins IEA Gallus gallus A0A1L1RQY7 R-GGA-8867756 https://reactome.org/PathwayBrowser/#/R-GGA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Gallus gallus A0A1L1RQY7 R-GGA-8868071 https://reactome.org/PathwayBrowser/#/R-GGA-8868071 Clathrin recruits PIK3C2A IEA Gallus gallus A0A1L1RQY7 R-GGA-8868072 https://reactome.org/PathwayBrowser/#/R-GGA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Gallus gallus A0A1L1RQY7 R-GGA-8868230 https://reactome.org/PathwayBrowser/#/R-GGA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Gallus gallus A0A1L1RQY7 R-GGA-8868236 https://reactome.org/PathwayBrowser/#/R-GGA-8868236 BAR domain proteins recruit dynamin IEA Gallus gallus A0A1L1RQY7 R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus A0A1L1RQY7 R-GGA-8868651 https://reactome.org/PathwayBrowser/#/R-GGA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Gallus gallus A0A1L1RQY7 R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus A0A1L1RQY7 R-GGA-8868659 https://reactome.org/PathwayBrowser/#/R-GGA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Gallus gallus A0A1L1RQY7 R-GGA-8868660 https://reactome.org/PathwayBrowser/#/R-GGA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Gallus gallus A0A1L1RQY7 R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus A0A1L1RQY7 R-GGA-8871194 https://reactome.org/PathwayBrowser/#/R-GGA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Gallus gallus A0A1L1RR22 R-GGA-1226094 https://reactome.org/PathwayBrowser/#/R-GGA-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Gallus gallus A0A1L1RR22 R-GGA-1227670 https://reactome.org/PathwayBrowser/#/R-GGA-1227670 Recruitment of HDAC1 by p130 (RBL2) IEA Gallus gallus A0A1L1RR22 R-GGA-1362261 https://reactome.org/PathwayBrowser/#/R-GGA-1362261 p130 (RBL2) associates with MuvB to form DREAM complex IEA Gallus gallus A0A1L1RR22 R-GGA-1363303 https://reactome.org/PathwayBrowser/#/R-GGA-1363303 p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 IEA Gallus gallus A0A1L1RR22 R-GGA-1363306 https://reactome.org/PathwayBrowser/#/R-GGA-1363306 p130 (RBL2) binds Cyclin E/A:CDK2 IEA Gallus gallus A0A1L1RR22 R-GGA-1363328 https://reactome.org/PathwayBrowser/#/R-GGA-1363328 Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex IEA Gallus gallus A0A1L1RR22 R-GGA-1363331 https://reactome.org/PathwayBrowser/#/R-GGA-1363331 Ubiquitination of p130 (RBL2) by SCF (Skp2) IEA Gallus gallus A0A1L1RRA1 R-GGA-5250930 https://reactome.org/PathwayBrowser/#/R-GGA-5250930 B-WICH recruits histone acetyltransferases IEA Gallus gallus A0A1L1RRA1 R-GGA-5250938 https://reactome.org/PathwayBrowser/#/R-GGA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Gallus gallus A0A1L1RRA1 R-GGA-5250947 https://reactome.org/PathwayBrowser/#/R-GGA-5250947 B-WICH complex binds rDNA promoter IEA Gallus gallus A0A1L1RRA1 R-GGA-73757 https://reactome.org/PathwayBrowser/#/R-GGA-73757 Binding of RRN3 to RNA Polymerase I IEA Gallus gallus A0A1L1RRA1 R-GGA-73758 https://reactome.org/PathwayBrowser/#/R-GGA-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Gallus gallus A0A1L1RRA1 R-GGA-73769 https://reactome.org/PathwayBrowser/#/R-GGA-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Gallus gallus A0A1L1RRA1 R-GGA-74986 https://reactome.org/PathwayBrowser/#/R-GGA-74986 Elongation of pre-rRNA transcript IEA Gallus gallus A0A1L1RRA1 R-GGA-74993 https://reactome.org/PathwayBrowser/#/R-GGA-74993 PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box IEA Gallus gallus A0A1L1RRB0 R-GGA-392051 https://reactome.org/PathwayBrowser/#/R-GGA-392051 Recruitment of Grb2 to pFAK:NCAM1 IEA Gallus gallus A0A1L1RRB0 R-GGA-392053 https://reactome.org/PathwayBrowser/#/R-GGA-392053 SOS binds Grb2 bound to pFAK:NCAM1 IEA Gallus gallus A0A1L1RRB0 R-GGA-392054 https://reactome.org/PathwayBrowser/#/R-GGA-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Gallus gallus A0A1L1RRB0 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1L1RRE2 R-GGA-5624949 https://reactome.org/PathwayBrowser/#/R-GGA-5624949 Assembly of the anterograde IFT train IEA Gallus gallus A0A1L1RRE2 R-GGA-5625416 https://reactome.org/PathwayBrowser/#/R-GGA-5625416 Anterograde IFT IEA Gallus gallus A0A1L1RRE2 R-GGA-5625426 https://reactome.org/PathwayBrowser/#/R-GGA-5625426 Retrograde IFT IEA Gallus gallus A0A1L1RRE7 R-GGA-141423 https://reactome.org/PathwayBrowser/#/R-GGA-141423 Binding of the MCC complex to the APC/C complex IEA Gallus gallus A0A1L1RRE7 R-GGA-174057 https://reactome.org/PathwayBrowser/#/R-GGA-174057 Multiubiquitination of APC/C-associated Cdh1 IEA Gallus gallus A0A1L1RRE7 R-GGA-174058 https://reactome.org/PathwayBrowser/#/R-GGA-174058 Degradation of multiubiquitinated Cdh1 IEA Gallus gallus A0A1L1RRE7 R-GGA-174070 https://reactome.org/PathwayBrowser/#/R-GGA-174070 Association of Cdh1 with the APC/C IEA Gallus gallus A0A1L1RRE7 R-GGA-174079 https://reactome.org/PathwayBrowser/#/R-GGA-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Gallus gallus A0A1L1RRE7 R-GGA-174088 https://reactome.org/PathwayBrowser/#/R-GGA-174088 Association of cell cycle proteins with the APC/C:Cdh1 complex IEA Gallus gallus A0A1L1RRE7 R-GGA-174104 https://reactome.org/PathwayBrowser/#/R-GGA-174104 Ubiquitination of Cyclin A by APC/C:Cdc20 complex IEA Gallus gallus A0A1L1RRE7 R-GGA-174105 https://reactome.org/PathwayBrowser/#/R-GGA-174105 Degradation of multiubiquitinated cell cycle proteins IEA Gallus gallus A0A1L1RRE7 R-GGA-174119 https://reactome.org/PathwayBrowser/#/R-GGA-174119 Free APC/C phosphorylated by Plk1 IEA Gallus gallus A0A1L1RRE7 R-GGA-174121 https://reactome.org/PathwayBrowser/#/R-GGA-174121 Association of Securin with Cdc20:APC/C complex IEA Gallus gallus A0A1L1RRE7 R-GGA-174139 https://reactome.org/PathwayBrowser/#/R-GGA-174139 Dissociation of phospho-Cdh1 from the APC/C complex IEA Gallus gallus A0A1L1RRE7 R-GGA-174144 https://reactome.org/PathwayBrowser/#/R-GGA-174144 Ubiquitination of Securin by phospho-APC/C:Cdc20 complex IEA Gallus gallus A0A1L1RRE7 R-GGA-174157 https://reactome.org/PathwayBrowser/#/R-GGA-174157 Degradation of multiubiquitinated Cyclin B IEA Gallus gallus A0A1L1RRE7 R-GGA-174171 https://reactome.org/PathwayBrowser/#/R-GGA-174171 Association of Cyclin A with the APC/C IEA Gallus gallus A0A1L1RRE7 R-GGA-174195 https://reactome.org/PathwayBrowser/#/R-GGA-174195 Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex IEA Gallus gallus A0A1L1RRE7 R-GGA-174202 https://reactome.org/PathwayBrowser/#/R-GGA-174202 Degradation of multiubiquitinated Securin IEA Gallus gallus A0A1L1RRE7 R-GGA-174224 https://reactome.org/PathwayBrowser/#/R-GGA-174224 Dissociation of Cdc20 from APC/C complex IEA Gallus gallus A0A1L1RRE7 R-GGA-174227 https://reactome.org/PathwayBrowser/#/R-GGA-174227 Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex IEA Gallus gallus A0A1L1RRE7 R-GGA-174238 https://reactome.org/PathwayBrowser/#/R-GGA-174238 Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 IEA Gallus gallus A0A1L1RRE7 R-GGA-174255 https://reactome.org/PathwayBrowser/#/R-GGA-174255 Degradation multiubiquitinated Cyclin A IEA Gallus gallus A0A1L1RRE7 R-GGA-179410 https://reactome.org/PathwayBrowser/#/R-GGA-179410 Association of Nek2A with MCC:APC/C IEA Gallus gallus A0A1L1RRE7 R-GGA-179417 https://reactome.org/PathwayBrowser/#/R-GGA-179417 Multiubiquitination of Nek2A IEA Gallus gallus A0A1L1RRE7 R-GGA-179421 https://reactome.org/PathwayBrowser/#/R-GGA-179421 Degradation of multiubiquitinated Nek2A IEA Gallus gallus A0A1L1RRE7 R-GGA-188191 https://reactome.org/PathwayBrowser/#/R-GGA-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Gallus gallus A0A1L1RRE7 R-GGA-188371 https://reactome.org/PathwayBrowser/#/R-GGA-188371 Association of Cyclin A:Cdk2 with Cdh1 IEA Gallus gallus A0A1L1RRE7 R-GGA-3788705 https://reactome.org/PathwayBrowser/#/R-GGA-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Gallus gallus A0A1L1RRE7 R-GGA-3788708 https://reactome.org/PathwayBrowser/#/R-GGA-3788708 CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 IEA Gallus gallus A0A1L1RRE7 R-GGA-3788724 https://reactome.org/PathwayBrowser/#/R-GGA-3788724 Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 IEA Gallus gallus A0A1L1RRE7 R-GGA-68712 https://reactome.org/PathwayBrowser/#/R-GGA-68712 The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 IEA Gallus gallus A0A1L1RRE7 R-GGA-69015 https://reactome.org/PathwayBrowser/#/R-GGA-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Gallus gallus A0A1L1RRE7 R-GGA-9686969 https://reactome.org/PathwayBrowser/#/R-GGA-9686969 APC/C:Cdh1 polyubiquitinates SKP2 IEA Gallus gallus A0A1L1RRE7 R-GGA-9686980 https://reactome.org/PathwayBrowser/#/R-GGA-9686980 RB1 recruits APC/C:Cdh1 complex to SKP2 IEA Gallus gallus A0A1L1RRE7 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1L1RRE7 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1L1RRE7 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1L1RRE7 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1L1RRF3 R-GGA-445797 https://reactome.org/PathwayBrowser/#/R-GGA-445797 MYLK (MLCK) Active Calmodulin Binding IEA Gallus gallus A0A1L1RRF3 R-GGA-445813 https://reactome.org/PathwayBrowser/#/R-GGA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Gallus gallus A0A1L1RRF3 R-GGA-5668984 https://reactome.org/PathwayBrowser/#/R-GGA-5668984 PAK1 or PAK2 phosphorylates MYLK IEA Gallus gallus A0A1L1RRI7 R-GGA-446189 https://reactome.org/PathwayBrowser/#/R-GGA-446189 Addition of a second glucose to the N-glycan precursor by ALG8 IEA Gallus gallus A0A1L1RRL8 R-GGA-198955 https://reactome.org/PathwayBrowser/#/R-GGA-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Gallus gallus A0A1L1RRM0 R-GGA-917693 https://reactome.org/PathwayBrowser/#/R-GGA-917693 ESCRT Disassembly IEA Gallus gallus A0A1L1RRN7 R-GGA-70494 https://reactome.org/PathwayBrowser/#/R-GGA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Gallus gallus A0A1L1RRN7 R-GGA-71660 https://reactome.org/PathwayBrowser/#/R-GGA-71660 Enolase dimers dehydrates 2PG IEA Gallus gallus A0A1L1RRQ2 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A1L1RRQ2 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A1L1RRQ2 R-GGA-141423 https://reactome.org/PathwayBrowser/#/R-GGA-141423 Binding of the MCC complex to the APC/C complex IEA Gallus gallus A0A1L1RRQ2 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A1L1RRQ2 R-GGA-141437 https://reactome.org/PathwayBrowser/#/R-GGA-141437 Formation of the MCC complex IEA Gallus gallus A0A1L1RRQ2 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A1L1RRQ2 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1L1RRQ2 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1L1RRQ2 R-GGA-174104 https://reactome.org/PathwayBrowser/#/R-GGA-174104 Ubiquitination of Cyclin A by APC/C:Cdc20 complex IEA Gallus gallus A0A1L1RRQ2 R-GGA-174171 https://reactome.org/PathwayBrowser/#/R-GGA-174171 Association of Cyclin A with the APC/C IEA Gallus gallus A0A1L1RRQ2 R-GGA-174238 https://reactome.org/PathwayBrowser/#/R-GGA-174238 Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 IEA Gallus gallus A0A1L1RRQ2 R-GGA-174255 https://reactome.org/PathwayBrowser/#/R-GGA-174255 Degradation multiubiquitinated Cyclin A IEA Gallus gallus A0A1L1RRQ2 R-GGA-179410 https://reactome.org/PathwayBrowser/#/R-GGA-179410 Association of Nek2A with MCC:APC/C IEA Gallus gallus A0A1L1RRQ2 R-GGA-179417 https://reactome.org/PathwayBrowser/#/R-GGA-179417 Multiubiquitination of Nek2A IEA Gallus gallus A0A1L1RRQ2 R-GGA-179421 https://reactome.org/PathwayBrowser/#/R-GGA-179421 Degradation of multiubiquitinated Nek2A IEA Gallus gallus A0A1L1RRQ2 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1L1RRQ2 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1L1RRQ2 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1L1RRQ2 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A1L1RRQ2 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1L1RRQ3 R-GGA-5624949 https://reactome.org/PathwayBrowser/#/R-GGA-5624949 Assembly of the anterograde IFT train IEA Gallus gallus A0A1L1RRQ3 R-GGA-5625416 https://reactome.org/PathwayBrowser/#/R-GGA-5625416 Anterograde IFT IEA Gallus gallus A0A1L1RRQ3 R-GGA-5625426 https://reactome.org/PathwayBrowser/#/R-GGA-5625426 Retrograde IFT IEA Gallus gallus A0A1L1RRQ3 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1L1RRQ3 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1L1RRQ3 R-GGA-983259 https://reactome.org/PathwayBrowser/#/R-GGA-983259 Kinesins move along microtubules consuming ATP IEA Gallus gallus A0A1L1RRQ8 R-GGA-203973 https://reactome.org/PathwayBrowser/#/R-GGA-203973 Vesicle budding IEA Gallus gallus A0A1L1RRQ8 R-GGA-204008 https://reactome.org/PathwayBrowser/#/R-GGA-204008 SEC31:SEC13 and v-SNARE recruitment IEA Gallus gallus A0A1L1RRQ8 R-GGA-481007 https://reactome.org/PathwayBrowser/#/R-GGA-481007 Exocytosis of platelet alpha granule contents IEA Gallus gallus A0A1L1RRQ8 R-GGA-5694409 https://reactome.org/PathwayBrowser/#/R-GGA-5694409 Nucleotide exchange on RAB1 IEA Gallus gallus A0A1L1RRQ8 R-GGA-5694417 https://reactome.org/PathwayBrowser/#/R-GGA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Gallus gallus A0A1L1RRQ8 R-GGA-5694418 https://reactome.org/PathwayBrowser/#/R-GGA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Gallus gallus A0A1L1RRQ8 R-GGA-5694428 https://reactome.org/PathwayBrowser/#/R-GGA-5694428 LMAN family proteins bind glycosylated cargo IEA Gallus gallus A0A1L1RRQ8 R-GGA-5694446 https://reactome.org/PathwayBrowser/#/R-GGA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Gallus gallus A0A1L1RRQ8 R-GGA-5694522 https://reactome.org/PathwayBrowser/#/R-GGA-5694522 Inner coat assembly and cargo binding IEA Gallus gallus A0A1L1RRQ8 R-GGA-5694527 https://reactome.org/PathwayBrowser/#/R-GGA-5694527 Loss of SAR1B GTPase IEA Gallus gallus A0A1L1RRQ8 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1L1RRQ8 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1L1RRS1 R-GGA-5696146 https://reactome.org/PathwayBrowser/#/R-GGA-5696146 AOC2 deaminates TYR IEA Gallus gallus A0A1L1RRS1 R-GGA-5696183 https://reactome.org/PathwayBrowser/#/R-GGA-5696183 AOC3 deaminates BZAM IEA Gallus gallus A0A1L1RRT5 R-GGA-8852013 https://reactome.org/PathwayBrowser/#/R-GGA-8852013 BTNL8 binds resting T cell surface IEA Gallus gallus A0A1L1RRU5 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1L1RRU5 R-GGA-9842833 https://reactome.org/PathwayBrowser/#/R-GGA-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Gallus gallus A0A1L1RRU5 R-GGA-9842835 https://reactome.org/PathwayBrowser/#/R-GGA-9842835 KRAB-ZFP binds retroelement DNA in chromatin IEA Gallus gallus A0A1L1RRU5 R-GGA-9842839 https://reactome.org/PathwayBrowser/#/R-GGA-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1L1RRU5 R-GGA-9843978 https://reactome.org/PathwayBrowser/#/R-GGA-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1L1RRW6 R-GGA-448963 https://reactome.org/PathwayBrowser/#/R-GGA-448963 Interaction of MyoD:E protein with MEF2 IEA Gallus gallus A0A1L1RS10 R-GGA-6791222 https://reactome.org/PathwayBrowser/#/R-GGA-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Gallus gallus A0A1L1RS10 R-GGA-6791227 https://reactome.org/PathwayBrowser/#/R-GGA-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Gallus gallus A0A1L1RS19 R-GGA-2130706 https://reactome.org/PathwayBrowser/#/R-GGA-2130706 MHC class II antigen processing IEA Gallus gallus A0A1L1RS19 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1L1RS25 R-GGA-9860264 https://reactome.org/PathwayBrowser/#/R-GGA-9860264 TASL is phosphorylated IEA Gallus gallus A0A1L1RS25 R-GGA-9860290 https://reactome.org/PathwayBrowser/#/R-GGA-9860290 TASL recruits IRF5 IEA Gallus gallus A0A1L1RS25 R-GGA-9860295 https://reactome.org/PathwayBrowser/#/R-GGA-9860295 SLC15A4 binds TASL IEA Gallus gallus A0A1L1RS34 R-GGA-5250930 https://reactome.org/PathwayBrowser/#/R-GGA-5250930 B-WICH recruits histone acetyltransferases IEA Gallus gallus A0A1L1RS34 R-GGA-5250938 https://reactome.org/PathwayBrowser/#/R-GGA-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Gallus gallus A0A1L1RS34 R-GGA-5250947 https://reactome.org/PathwayBrowser/#/R-GGA-5250947 B-WICH complex binds rDNA promoter IEA Gallus gallus A0A1L1RS34 R-GGA-73757 https://reactome.org/PathwayBrowser/#/R-GGA-73757 Binding of RRN3 to RNA Polymerase I IEA Gallus gallus A0A1L1RS34 R-GGA-73758 https://reactome.org/PathwayBrowser/#/R-GGA-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Gallus gallus A0A1L1RS34 R-GGA-73769 https://reactome.org/PathwayBrowser/#/R-GGA-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Gallus gallus A0A1L1RS34 R-GGA-74986 https://reactome.org/PathwayBrowser/#/R-GGA-74986 Elongation of pre-rRNA transcript IEA Gallus gallus A0A1L1RS34 R-GGA-74993 https://reactome.org/PathwayBrowser/#/R-GGA-74993 PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box IEA Gallus gallus A0A1L1RS34 R-GGA-76056 https://reactome.org/PathwayBrowser/#/R-GGA-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Gallus gallus A0A1L1RS34 R-GGA-83803 https://reactome.org/PathwayBrowser/#/R-GGA-83803 Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex IEA Gallus gallus A0A1L1RS34 R-GGA-83805 https://reactome.org/PathwayBrowser/#/R-GGA-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Gallus gallus A0A1L1RS36 R-GGA-4420140 https://reactome.org/PathwayBrowser/#/R-GGA-4420140 SRC1-1 binds SH2D2A and is recruited to VEGFR2 IEA Gallus gallus A0A1L1RS36 R-GGA-4420143 https://reactome.org/PathwayBrowser/#/R-GGA-4420143 p-6Y-VEGFR2 binds SH2D2A IEA Gallus gallus A0A1L1RS36 R-GGA-4420206 https://reactome.org/PathwayBrowser/#/R-GGA-4420206 Phosphorylation of SRC-1 IEA Gallus gallus A0A1L1RS36 R-GGA-5218819 https://reactome.org/PathwayBrowser/#/R-GGA-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1L1RS36 R-GGA-5357429 https://reactome.org/PathwayBrowser/#/R-GGA-5357429 AXL autophosphorylates on Y779 and Y821 IEA Gallus gallus A0A1L1RS36 R-GGA-5357479 https://reactome.org/PathwayBrowser/#/R-GGA-5357479 p-AXL binds PI3K IEA Gallus gallus A0A1L1RS37 R-GGA-77254 https://reactome.org/PathwayBrowser/#/R-GGA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Gallus gallus A0A1L1RS37 R-GGA-77312 https://reactome.org/PathwayBrowser/#/R-GGA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Gallus gallus A0A1L1RS37 R-GGA-77323 https://reactome.org/PathwayBrowser/#/R-GGA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Gallus gallus A0A1L1RS37 R-GGA-77331 https://reactome.org/PathwayBrowser/#/R-GGA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Gallus gallus A0A1L1RS37 R-GGA-77342 https://reactome.org/PathwayBrowser/#/R-GGA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Gallus gallus A0A1L1RS37 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1L1RS37 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1L1RS61 R-GGA-8953917 https://reactome.org/PathwayBrowser/#/R-GGA-8953917 PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 IEA Gallus gallus A0A1L1RS61 R-GGA-8953946 https://reactome.org/PathwayBrowser/#/R-GGA-8953946 PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 IEA Gallus gallus A0A1L1RS61 R-GGA-9033235 https://reactome.org/PathwayBrowser/#/R-GGA-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1L1RS61 R-GGA-9033236 https://reactome.org/PathwayBrowser/#/R-GGA-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Gallus gallus A0A1L1RS61 R-GGA-9033485 https://reactome.org/PathwayBrowser/#/R-GGA-9033485 PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 IEA Gallus gallus A0A1L1RS61 R-GGA-9033499 https://reactome.org/PathwayBrowser/#/R-GGA-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Gallus gallus A0A1L1RS61 R-GGA-9033514 https://reactome.org/PathwayBrowser/#/R-GGA-9033514 Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1L1RS61 R-GGA-9033516 https://reactome.org/PathwayBrowser/#/R-GGA-9033516 PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Gallus gallus A0A1L1RS61 R-GGA-9033527 https://reactome.org/PathwayBrowser/#/R-GGA-9033527 PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 IEA Gallus gallus A0A1L1RS61 R-GGA-9033533 https://reactome.org/PathwayBrowser/#/R-GGA-9033533 PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Gallus gallus A0A1L1RS61 R-GGA-9603775 https://reactome.org/PathwayBrowser/#/R-GGA-9603775 PEX3:PEX19:class I PMP dissociates IEA Gallus gallus A0A1L1RS61 R-GGA-9603784 https://reactome.org/PathwayBrowser/#/R-GGA-9603784 PEX19:class I PMP binds PEX3 IEA Gallus gallus A0A1L1RS61 R-GGA-9603804 https://reactome.org/PathwayBrowser/#/R-GGA-9603804 PEX19 binds class I peroxisomal membrane proteins IEA Gallus gallus A0A1L1RSB5 R-GGA-111437 https://reactome.org/PathwayBrowser/#/R-GGA-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Gallus gallus A0A1L1RSB5 R-GGA-111438 https://reactome.org/PathwayBrowser/#/R-GGA-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Gallus gallus A0A1L1RSB5 R-GGA-191763 https://reactome.org/PathwayBrowser/#/R-GGA-191763 snRNP:Snurportin complex formation IEA Gallus gallus A0A1L1RSB5 R-GGA-191784 https://reactome.org/PathwayBrowser/#/R-GGA-191784 snRNA Cap hypermethylation IEA Gallus gallus A0A1L1RSB5 R-GGA-191830 https://reactome.org/PathwayBrowser/#/R-GGA-191830 snRNP nuclear import and release IEA Gallus gallus A0A1L1RSB5 R-GGA-75079 https://reactome.org/PathwayBrowser/#/R-GGA-75079 Formation of AT-AC C complex IEA Gallus gallus A0A1L1RSB5 R-GGA-75081 https://reactome.org/PathwayBrowser/#/R-GGA-75081 Formation of AT-AC B Complex IEA Gallus gallus A0A1L1RSB5 R-GGA-75082 https://reactome.org/PathwayBrowser/#/R-GGA-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Gallus gallus A0A1L1RSB5 R-GGA-75083 https://reactome.org/PathwayBrowser/#/R-GGA-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Gallus gallus A0A1L1RSB5 R-GGA-77585 https://reactome.org/PathwayBrowser/#/R-GGA-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Gallus gallus A0A1L1RSB5 R-GGA-77586 https://reactome.org/PathwayBrowser/#/R-GGA-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Gallus gallus A0A1L1RSB5 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1L1RSD2 R-GGA-1678854 https://reactome.org/PathwayBrowser/#/R-GGA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Gallus gallus A0A1L1RSD2 R-GGA-2162226 https://reactome.org/PathwayBrowser/#/R-GGA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Gallus gallus A0A1L1RSD2 R-GGA-2162227 https://reactome.org/PathwayBrowser/#/R-GGA-2162227 GUSB tetramer hydrolyses (HA)2 IEA Gallus gallus A0A1L1RSD2 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1L1RSD2 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1L1RSD4 R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus A0A1L1RSD4 R-GGA-9647987 https://reactome.org/PathwayBrowser/#/R-GGA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Gallus gallus A0A1L1RSF6 R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus A0A1L1RSG1 R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus A0A1L1RSG1 R-GGA-9709406 https://reactome.org/PathwayBrowser/#/R-GGA-9709406 CO binds to Cytochrome c oxidase IEA Gallus gallus A0A1L1RSG3 R-GGA-74372 https://reactome.org/PathwayBrowser/#/R-GGA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Gallus gallus A0A1L1RSG3 R-GGA-74376 https://reactome.org/PathwayBrowser/#/R-GGA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Gallus gallus A0A1L1RSI0 R-GGA-141139 https://reactome.org/PathwayBrowser/#/R-GGA-141139 Trimerization of TRAIL:TRAIL receptor complex IEA Gallus gallus A0A1L1RSI0 R-GGA-141156 https://reactome.org/PathwayBrowser/#/R-GGA-141156 TRAIL-mediated dimerization of procaspase-8 IEA Gallus gallus A0A1L1RSI0 R-GGA-141316 https://reactome.org/PathwayBrowser/#/R-GGA-141316 TRAIL:TRAIL-Receptor2 Trimer:FADD complex binds procaspase-10 IEA Gallus gallus A0A1L1RSI0 R-GGA-3371359 https://reactome.org/PathwayBrowser/#/R-GGA-3371359 FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling IEA Gallus gallus A0A1L1RSI0 R-GGA-3465429 https://reactome.org/PathwayBrowser/#/R-GGA-3465429 FLIP(S) and procaspase-8 form heterodimer IEA Gallus gallus A0A1L1RSI0 R-GGA-3465448 https://reactome.org/PathwayBrowser/#/R-GGA-3465448 Caspase-8 and FLIP(L) processing at DISC IEA Gallus gallus A0A1L1RSI0 R-GGA-5675456 https://reactome.org/PathwayBrowser/#/R-GGA-5675456 FLIP(L) and procaspase-8 form heterodimer IEA Gallus gallus A0A1L1RSI0 R-GGA-75146 https://reactome.org/PathwayBrowser/#/R-GGA-75146 TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 IEA Gallus gallus A0A1L1RSI0 R-GGA-75187 https://reactome.org/PathwayBrowser/#/R-GGA-75187 TRAIL:TRAIL receptor trimers bind FADD IEA Gallus gallus A0A1L1RSI0 R-GGA-75238 https://reactome.org/PathwayBrowser/#/R-GGA-75238 TRAIL binds TRAIL receptors IEA Gallus gallus A0A1L1RSJ2 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1L1RSJ2 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1L1RSJ4 R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus A0A1L1RSJ4 R-GGA-8948232 https://reactome.org/PathwayBrowser/#/R-GGA-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Gallus gallus A0A1L1RSK6 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1L1RSK6 R-GGA-9842833 https://reactome.org/PathwayBrowser/#/R-GGA-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Gallus gallus A0A1L1RSK6 R-GGA-9842835 https://reactome.org/PathwayBrowser/#/R-GGA-9842835 KRAB-ZFP binds retroelement DNA in chromatin IEA Gallus gallus A0A1L1RSK6 R-GGA-9842839 https://reactome.org/PathwayBrowser/#/R-GGA-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1L1RSK6 R-GGA-9843978 https://reactome.org/PathwayBrowser/#/R-GGA-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1L1RSN0 R-GGA-6791222 https://reactome.org/PathwayBrowser/#/R-GGA-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Gallus gallus A0A1L1RSN0 R-GGA-6791227 https://reactome.org/PathwayBrowser/#/R-GGA-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Gallus gallus A0A1L1RSN3 R-GGA-72697 https://reactome.org/PathwayBrowser/#/R-GGA-72697 Start codon recognition IEA Gallus gallus A0A1L1RSP4 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1L1RSS5 R-GGA-5696074 https://reactome.org/PathwayBrowser/#/R-GGA-5696074 AGK:Mg2+ phosphorylates MAG, DAG IEA Gallus gallus A0A1L1RSU2 R-GGA-73647 https://reactome.org/PathwayBrowser/#/R-GGA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Gallus gallus A0A1L1RSU7 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1L1RSU7 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1L1RSX2 R-GGA-8875523 https://reactome.org/PathwayBrowser/#/R-GGA-8875523 MET binds TNS3 IEA Gallus gallus A0A1L1RSX4 R-GGA-6797627 https://reactome.org/PathwayBrowser/#/R-GGA-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Gallus gallus A0A1L1RSX7 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1L1RSX7 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1L1RSX7 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1L1RSX7 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1L1RSX7 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1L1RSX7 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1L1RSX7 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1L1RT07 R-GGA-1605632 https://reactome.org/PathwayBrowser/#/R-GGA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Gallus gallus A0A1L1RT07 R-GGA-1638053 https://reactome.org/PathwayBrowser/#/R-GGA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Gallus gallus A0A1L1RT07 R-GGA-2105001 https://reactome.org/PathwayBrowser/#/R-GGA-2105001 HEXA cleaves the terminal GalNAc from DS IEA Gallus gallus A0A1L1RT07 R-GGA-2162225 https://reactome.org/PathwayBrowser/#/R-GGA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Gallus gallus A0A1L1RT49 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus A0A1L1RT49 R-GGA-75097 https://reactome.org/PathwayBrowser/#/R-GGA-75097 Transport of the export-competent mRNP complex through the NPC IEA Gallus gallus A0A1L1RT49 R-GGA-75098 https://reactome.org/PathwayBrowser/#/R-GGA-75098 mRNP complex dissociates from cytosolic face of NPC IEA Gallus gallus A0A1L1RT49 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1L1RT49 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1L1RT49 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1L1RT70 R-GGA-9914364 https://reactome.org/PathwayBrowser/#/R-GGA-9914364 POLG in the replisome polymerizes the H strand IEA Gallus gallus A0A1L1RT70 R-GGA-9914404 https://reactome.org/PathwayBrowser/#/R-GGA-9914404 POLRMT and POLG bind the mitochondrial L strand replication origin (OriL) IEA Gallus gallus A0A1L1RT70 R-GGA-9914409 https://reactome.org/PathwayBrowser/#/R-GGA-9914409 POLRMT polymerizes RNA primer for mitochondrial L strand replication IEA Gallus gallus A0A1L1RT70 R-GGA-9914438 https://reactome.org/PathwayBrowser/#/R-GGA-9914438 TWNK (PEO1) unwinds double-stranded mitochondrial DNA at the replication fork IEA Gallus gallus A0A1L1RT70 R-GGA-9914478 https://reactome.org/PathwayBrowser/#/R-GGA-9914478 SSBP1 binds the displaced parental H strand IEA Gallus gallus A0A1L1RT70 R-GGA-9914498 https://reactome.org/PathwayBrowser/#/R-GGA-9914498 POLG in the replisome polymerizes the L strand IEA Gallus gallus A0A1L1RT71 R-GGA-191422 https://reactome.org/PathwayBrowser/#/R-GGA-191422 Mevalonate-5-phosphate is further phosphorylated IEA Gallus gallus A0A1L1RT72 R-GGA-446207 https://reactome.org/PathwayBrowser/#/R-GGA-446207 ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP IEA Gallus gallus A0A1L1RT94 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1L1RT94 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1L1RT94 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1L1RT94 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1L1RT94 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1L1RT94 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1L1RT94 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1L1RTH0 R-GGA-2559456 https://reactome.org/PathwayBrowser/#/R-GGA-2559456 TIRAP binds PIP2-rich regions in the plasma membrane IEA Gallus gallus A0A1L1RTH3 R-GGA-193064 https://reactome.org/PathwayBrowser/#/R-GGA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Gallus gallus A0A1L1RTH3 R-GGA-548818 https://reactome.org/PathwayBrowser/#/R-GGA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Gallus gallus A0A1L1RTK2 R-GGA-8863721 https://reactome.org/PathwayBrowser/#/R-GGA-8863721 NEDD8-STON binds TOR1 hexamer and COP9 complex IEA Gallus gallus A0A1L1RTK2 R-GGA-8863723 https://reactome.org/PathwayBrowser/#/R-GGA-8863723 COP9 and TOR1 deneddylate STON2 IEA Gallus gallus A0A1L1RTK5 R-GGA-6791222 https://reactome.org/PathwayBrowser/#/R-GGA-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Gallus gallus A0A1L1RTK5 R-GGA-6791227 https://reactome.org/PathwayBrowser/#/R-GGA-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Gallus gallus A0A1L1RTK9 R-GGA-156808 https://reactome.org/PathwayBrowser/#/R-GGA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Gallus gallus A0A1L1RTK9 R-GGA-157849 https://reactome.org/PathwayBrowser/#/R-GGA-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Gallus gallus A0A1L1RTK9 R-GGA-165777 https://reactome.org/PathwayBrowser/#/R-GGA-165777 Phosphorylation and activation of eIF4B by activated S6K1 IEA Gallus gallus A0A1L1RTK9 R-GGA-429955 https://reactome.org/PathwayBrowser/#/R-GGA-429955 CCR4-NOT complex deadenylates mRNA IEA Gallus gallus A0A1L1RTK9 R-GGA-429992 https://reactome.org/PathwayBrowser/#/R-GGA-429992 PARN deadenylates mRNA IEA Gallus gallus A0A1L1RTK9 R-GGA-430021 https://reactome.org/PathwayBrowser/#/R-GGA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Gallus gallus A0A1L1RTK9 R-GGA-72621 https://reactome.org/PathwayBrowser/#/R-GGA-72621 Ribosomal scanning IEA Gallus gallus A0A1L1RTK9 R-GGA-72697 https://reactome.org/PathwayBrowser/#/R-GGA-72697 Start codon recognition IEA Gallus gallus A0A1L1RTL0 R-GGA-6799350 https://reactome.org/PathwayBrowser/#/R-GGA-6799350 Exocytosis of specific granule membrane proteins IEA Gallus gallus A0A1L1RTM0 R-GGA-8953917 https://reactome.org/PathwayBrowser/#/R-GGA-8953917 PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 IEA Gallus gallus A0A1L1RTM0 R-GGA-8953946 https://reactome.org/PathwayBrowser/#/R-GGA-8953946 PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 IEA Gallus gallus A0A1L1RTM0 R-GGA-9033235 https://reactome.org/PathwayBrowser/#/R-GGA-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1L1RTM0 R-GGA-9033236 https://reactome.org/PathwayBrowser/#/R-GGA-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Gallus gallus A0A1L1RTM0 R-GGA-9033485 https://reactome.org/PathwayBrowser/#/R-GGA-9033485 PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 IEA Gallus gallus A0A1L1RTM0 R-GGA-9033499 https://reactome.org/PathwayBrowser/#/R-GGA-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Gallus gallus A0A1L1RTM0 R-GGA-9033514 https://reactome.org/PathwayBrowser/#/R-GGA-9033514 Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1L1RTM0 R-GGA-9033516 https://reactome.org/PathwayBrowser/#/R-GGA-9033516 PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Gallus gallus A0A1L1RTM0 R-GGA-9033527 https://reactome.org/PathwayBrowser/#/R-GGA-9033527 PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 IEA Gallus gallus A0A1L1RTM0 R-GGA-9033533 https://reactome.org/PathwayBrowser/#/R-GGA-9033533 PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Gallus gallus A0A1L1RTN3 R-GGA-141409 https://reactome.org/PathwayBrowser/#/R-GGA-141409 Mad1 binds kinetochore IEA Gallus gallus A0A1L1RTN3 R-GGA-141422 https://reactome.org/PathwayBrowser/#/R-GGA-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Gallus gallus A0A1L1RTN3 R-GGA-141431 https://reactome.org/PathwayBrowser/#/R-GGA-141431 MAD2 associates with the Mad1 kinetochore complex IEA Gallus gallus A0A1L1RTN3 R-GGA-141439 https://reactome.org/PathwayBrowser/#/R-GGA-141439 Release of activated MAD2 from kinetochores IEA Gallus gallus A0A1L1RTN3 R-GGA-1638803 https://reactome.org/PathwayBrowser/#/R-GGA-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Gallus gallus A0A1L1RTN3 R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus A0A1L1RTN3 R-GGA-195275 https://reactome.org/PathwayBrowser/#/R-GGA-195275 Phosphorylation of APC component of the destruction complex IEA Gallus gallus A0A1L1RTN3 R-GGA-195280 https://reactome.org/PathwayBrowser/#/R-GGA-195280 Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex IEA Gallus gallus A0A1L1RTN3 R-GGA-195283 https://reactome.org/PathwayBrowser/#/R-GGA-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Gallus gallus A0A1L1RTN3 R-GGA-195287 https://reactome.org/PathwayBrowser/#/R-GGA-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Gallus gallus A0A1L1RTN3 R-GGA-195300 https://reactome.org/PathwayBrowser/#/R-GGA-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Gallus gallus A0A1L1RTN3 R-GGA-195304 https://reactome.org/PathwayBrowser/#/R-GGA-195304 Association of beta-catenin with the destruction complex IEA Gallus gallus A0A1L1RTN3 R-GGA-195318 https://reactome.org/PathwayBrowser/#/R-GGA-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Gallus gallus A0A1L1RTN3 R-GGA-2130279 https://reactome.org/PathwayBrowser/#/R-GGA-2130279 Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex IEA Gallus gallus A0A1L1RTN3 R-GGA-2130282 https://reactome.org/PathwayBrowser/#/R-GGA-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Gallus gallus A0A1L1RTN3 R-GGA-2130286 https://reactome.org/PathwayBrowser/#/R-GGA-2130286 Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) IEA Gallus gallus A0A1L1RTN3 R-GGA-2467809 https://reactome.org/PathwayBrowser/#/R-GGA-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Gallus gallus A0A1L1RTN3 R-GGA-2468287 https://reactome.org/PathwayBrowser/#/R-GGA-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Gallus gallus A0A1L1RTN3 R-GGA-2484822 https://reactome.org/PathwayBrowser/#/R-GGA-2484822 Kinetochore assembly IEA Gallus gallus A0A1L1RTN3 R-GGA-388808 https://reactome.org/PathwayBrowser/#/R-GGA-388808 CD28 homodimer binds B7-2 monomer IEA Gallus gallus A0A1L1RTN3 R-GGA-388809 https://reactome.org/PathwayBrowser/#/R-GGA-388809 CTLA-4 binds B7-1/B7-2 IEA Gallus gallus A0A1L1RTN3 R-GGA-388811 https://reactome.org/PathwayBrowser/#/R-GGA-388811 CD28 homodimer binds B7-1 homodimer IEA Gallus gallus A0A1L1RTN3 R-GGA-5229343 https://reactome.org/PathwayBrowser/#/R-GGA-5229343 AXIN is phosphorylated in the destruction complex IEA Gallus gallus A0A1L1RTN3 R-GGA-5666160 https://reactome.org/PathwayBrowser/#/R-GGA-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Gallus gallus A0A1L1RTN3 R-GGA-9648114 https://reactome.org/PathwayBrowser/#/R-GGA-9648114 EML4 recruits NUDC to mitotic spindle IEA Gallus gallus A0A1L1RTP0 R-GGA-8866275 https://reactome.org/PathwayBrowser/#/R-GGA-8866275 UBQLNs bind UIM-containing adaptor proteins IEA Gallus gallus A0A1L1RTQ1 R-GGA-2161950 https://reactome.org/PathwayBrowser/#/R-GGA-2161950 Arachidonate is oxidised to 12R-HpETE by ALOX12B IEA Gallus gallus A0A1L1RTQ1 R-GGA-2162002 https://reactome.org/PathwayBrowser/#/R-GGA-2162002 Arachidonate is oxidised to 15S-HpETE by ALOX15/15B IEA Gallus gallus A0A1L1RTQ1 R-GGA-8942208 https://reactome.org/PathwayBrowser/#/R-GGA-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Gallus gallus A0A1L1RTQ7 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1L1RTR9 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1L1RTR9 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1L1RTR9 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1L1RTR9 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1L1RTR9 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1L1RTR9 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1L1RTR9 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1L1RTX0 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1L1RTX7 R-GGA-446202 https://reactome.org/PathwayBrowser/#/R-GGA-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Gallus gallus A0A1L1RTY1 R-GGA-5689317 https://reactome.org/PathwayBrowser/#/R-GGA-5689317 Formation of the pre-incision complex in GG-NER IEA Gallus gallus A0A1L1RTY1 R-GGA-5690213 https://reactome.org/PathwayBrowser/#/R-GGA-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Gallus gallus A0A1L1RTY1 R-GGA-5690990 https://reactome.org/PathwayBrowser/#/R-GGA-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Gallus gallus A0A1L1RTY1 R-GGA-5690996 https://reactome.org/PathwayBrowser/#/R-GGA-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Gallus gallus A0A1L1RTY1 R-GGA-5696670 https://reactome.org/PathwayBrowser/#/R-GGA-5696670 CHD1L is recruited to GG-NER site IEA Gallus gallus A0A1L1RTY1 R-GGA-6790454 https://reactome.org/PathwayBrowser/#/R-GGA-6790454 SUMOylation of XPC IEA Gallus gallus A0A1L1RTY1 R-GGA-6790487 https://reactome.org/PathwayBrowser/#/R-GGA-6790487 RNF111 ubiquitinates SUMOylated XPC IEA Gallus gallus A0A1L1RU16 R-GGA-9033499 https://reactome.org/PathwayBrowser/#/R-GGA-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Gallus gallus A0A1L1RU16 R-GGA-9033516 https://reactome.org/PathwayBrowser/#/R-GGA-9033516 PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Gallus gallus A0A1L1RU16 R-GGA-9033533 https://reactome.org/PathwayBrowser/#/R-GGA-9033533 PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Gallus gallus A0A1L1RU90 R-GGA-1112666 https://reactome.org/PathwayBrowser/#/R-GGA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Gallus gallus A0A1L1RU90 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus A0A1L1RU90 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus A0A1L1RU90 R-GGA-173626 https://reactome.org/PathwayBrowser/#/R-GGA-173626 Activation of C1r IEA Gallus gallus A0A1L1RU90 R-GGA-173631 https://reactome.org/PathwayBrowser/#/R-GGA-173631 Activation of C1s IEA Gallus gallus A0A1L1RU90 R-GGA-1861621 https://reactome.org/PathwayBrowser/#/R-GGA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Gallus gallus A0A1L1RU90 R-GGA-199161 https://reactome.org/PathwayBrowser/#/R-GGA-199161 Fc gamma receptors interact with antigen-bound IgG IEA Gallus gallus A0A1L1RU90 R-GGA-2029268 https://reactome.org/PathwayBrowser/#/R-GGA-2029268 Phosphorylation and activation of PLCG IEA Gallus gallus A0A1L1RU90 R-GGA-2029270 https://reactome.org/PathwayBrowser/#/R-GGA-2029270 Recruitment of PLCgamma to membrane IEA Gallus gallus A0A1L1RU90 R-GGA-2029271 https://reactome.org/PathwayBrowser/#/R-GGA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1L1RU90 R-GGA-2029272 https://reactome.org/PathwayBrowser/#/R-GGA-2029272 Release of PLCG from FCGR IEA Gallus gallus A0A1L1RU90 R-GGA-2029273 https://reactome.org/PathwayBrowser/#/R-GGA-2029273 PI3K binds to p-6Y-SYK IEA Gallus gallus A0A1L1RU90 R-GGA-2029451 https://reactome.org/PathwayBrowser/#/R-GGA-2029451 Activation of RAC1 by VAV IEA Gallus gallus A0A1L1RU90 R-GGA-2029452 https://reactome.org/PathwayBrowser/#/R-GGA-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Gallus gallus A0A1L1RU90 R-GGA-2029453 https://reactome.org/PathwayBrowser/#/R-GGA-2029453 Phosphorylation of VAV IEA Gallus gallus A0A1L1RU90 R-GGA-2029455 https://reactome.org/PathwayBrowser/#/R-GGA-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Gallus gallus A0A1L1RU90 R-GGA-2029457 https://reactome.org/PathwayBrowser/#/R-GGA-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Gallus gallus A0A1L1RU90 R-GGA-2029458 https://reactome.org/PathwayBrowser/#/R-GGA-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Gallus gallus A0A1L1RU90 R-GGA-2029459 https://reactome.org/PathwayBrowser/#/R-GGA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Gallus gallus A0A1L1RU90 R-GGA-2029467 https://reactome.org/PathwayBrowser/#/R-GGA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Gallus gallus A0A1L1RU90 R-GGA-2029476 https://reactome.org/PathwayBrowser/#/R-GGA-2029476 Role of myosins in phagosome formation IEA Gallus gallus A0A1L1RU90 R-GGA-2197697 https://reactome.org/PathwayBrowser/#/R-GGA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Gallus gallus A0A1L1RU90 R-GGA-2203516 https://reactome.org/PathwayBrowser/#/R-GGA-2203516 Alpha-1-Microglobulin is cleaved IEA Gallus gallus A0A1L1RU90 R-GGA-8852266 https://reactome.org/PathwayBrowser/#/R-GGA-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Gallus gallus A0A1L1RU90 R-GGA-8852481 https://reactome.org/PathwayBrowser/#/R-GGA-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Gallus gallus A0A1L1RU90 R-GGA-8858428 https://reactome.org/PathwayBrowser/#/R-GGA-8858428 FCAMR binds IgA IEA Gallus gallus A0A1L1RU90 R-GGA-9021306 https://reactome.org/PathwayBrowser/#/R-GGA-9021306 C1-Inh binds and inactivates C1r, C1s IEA Gallus gallus A0A1L1RU90 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus A0A1L1RU90 R-GGA-9724685 https://reactome.org/PathwayBrowser/#/R-GGA-9724685 IgE binds omalizumab IEA Gallus gallus A0A1L1RU90 R-GGA-983696 https://reactome.org/PathwayBrowser/#/R-GGA-983696 The Immunoglobulin of the BCR binds antigen IEA Gallus gallus A0A1L1RU90 R-GGA-983700 https://reactome.org/PathwayBrowser/#/R-GGA-983700 SYK binds the activated BCR IEA Gallus gallus A0A1L1RU90 R-GGA-983703 https://reactome.org/PathwayBrowser/#/R-GGA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Gallus gallus A0A1L1RU90 R-GGA-983707 https://reactome.org/PathwayBrowser/#/R-GGA-983707 SYK autophosphorylates at the activated BCR IEA Gallus gallus A0A1L1RUB9 R-GGA-110307 https://reactome.org/PathwayBrowser/#/R-GGA-110307 REV1 binds AP-dsDNA IEA Gallus gallus A0A1L1RUB9 R-GGA-110308 https://reactome.org/PathwayBrowser/#/R-GGA-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Gallus gallus A0A1L1RUB9 R-GGA-110311 https://reactome.org/PathwayBrowser/#/R-GGA-110311 POLZ extends translesion synthesis IEA Gallus gallus A0A1L1RUB9 R-GGA-110316 https://reactome.org/PathwayBrowser/#/R-GGA-110316 POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template IEA Gallus gallus A0A1L1RUB9 R-GGA-110317 https://reactome.org/PathwayBrowser/#/R-GGA-110317 Insertion of correct bases opposite the lesion by POLH IEA Gallus gallus A0A1L1RUB9 R-GGA-110319 https://reactome.org/PathwayBrowser/#/R-GGA-110319 Elongation by POLH IEA Gallus gallus A0A1L1RUB9 R-GGA-174439 https://reactome.org/PathwayBrowser/#/R-GGA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Gallus gallus A0A1L1RUB9 R-GGA-174452 https://reactome.org/PathwayBrowser/#/R-GGA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Gallus gallus A0A1L1RUB9 R-GGA-176101 https://reactome.org/PathwayBrowser/#/R-GGA-176101 Recruitment of Rad17-RFC complex to DNA IEA Gallus gallus A0A1L1RUB9 R-GGA-176264 https://reactome.org/PathwayBrowser/#/R-GGA-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Gallus gallus A0A1L1RUB9 R-GGA-5652005 https://reactome.org/PathwayBrowser/#/R-GGA-5652005 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA IEA Gallus gallus A0A1L1RUB9 R-GGA-5652009 https://reactome.org/PathwayBrowser/#/R-GGA-5652009 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA IEA Gallus gallus A0A1L1RUB9 R-GGA-5652151 https://reactome.org/PathwayBrowser/#/R-GGA-5652151 REV1 recruits POLZ to (AP:Cyt)-DNA Template IEA Gallus gallus A0A1L1RUB9 R-GGA-5653756 https://reactome.org/PathwayBrowser/#/R-GGA-5653756 TRIM25 binds monoUb:164-PCNA IEA Gallus gallus A0A1L1RUB9 R-GGA-5653766 https://reactome.org/PathwayBrowser/#/R-GGA-5653766 USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Gallus gallus A0A1L1RUB9 R-GGA-5653770 https://reactome.org/PathwayBrowser/#/R-GGA-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Gallus gallus A0A1L1RUB9 R-GGA-5653780 https://reactome.org/PathwayBrowser/#/R-GGA-5653780 USP43 binds ISG:K164,ISG:K168-PCNA IEA Gallus gallus A0A1L1RUB9 R-GGA-5653838 https://reactome.org/PathwayBrowser/#/R-GGA-5653838 POLD,POLE binds deISGylated PCNA after TLS IEA Gallus gallus A0A1L1RUB9 R-GGA-5654985 https://reactome.org/PathwayBrowser/#/R-GGA-5654985 SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH IEA Gallus gallus A0A1L1RUB9 R-GGA-5654986 https://reactome.org/PathwayBrowser/#/R-GGA-5654986 SPRTN binds monoUb:K164-PCNA associated with POLH IEA Gallus gallus A0A1L1RUB9 R-GGA-5654989 https://reactome.org/PathwayBrowser/#/R-GGA-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Gallus gallus A0A1L1RUB9 R-GGA-5655466 https://reactome.org/PathwayBrowser/#/R-GGA-5655466 USP1:WDR48 deubiquitinates monoUb:K164-PCNA IEA Gallus gallus A0A1L1RUB9 R-GGA-5655481 https://reactome.org/PathwayBrowser/#/R-GGA-5655481 USP1:WDR48 binds monoUb:K164-PCNA IEA Gallus gallus A0A1L1RUB9 R-GGA-5655835 https://reactome.org/PathwayBrowser/#/R-GGA-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Gallus gallus A0A1L1RUB9 R-GGA-5655892 https://reactome.org/PathwayBrowser/#/R-GGA-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Gallus gallus A0A1L1RUB9 R-GGA-5655965 https://reactome.org/PathwayBrowser/#/R-GGA-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Gallus gallus A0A1L1RUB9 R-GGA-5656148 https://reactome.org/PathwayBrowser/#/R-GGA-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Gallus gallus A0A1L1RUB9 R-GGA-5656158 https://reactome.org/PathwayBrowser/#/R-GGA-5656158 POLZ elongates POLI-incorporated dNMP IEA Gallus gallus A0A1L1RUB9 R-GGA-5685011 https://reactome.org/PathwayBrowser/#/R-GGA-5685011 ATR activation at DNA DSBs IEA Gallus gallus A0A1L1RUB9 R-GGA-5685156 https://reactome.org/PathwayBrowser/#/R-GGA-5685156 ATR phosphorylates RPA2 IEA Gallus gallus A0A1L1RUB9 R-GGA-5686642 https://reactome.org/PathwayBrowser/#/R-GGA-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Gallus gallus A0A1L1RUB9 R-GGA-5690213 https://reactome.org/PathwayBrowser/#/R-GGA-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Gallus gallus A0A1L1RUB9 R-GGA-5691001 https://reactome.org/PathwayBrowser/#/R-GGA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Gallus gallus A0A1L1RUB9 R-GGA-5693564 https://reactome.org/PathwayBrowser/#/R-GGA-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Gallus gallus A0A1L1RUB9 R-GGA-5693580 https://reactome.org/PathwayBrowser/#/R-GGA-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Gallus gallus A0A1L1RUB9 R-GGA-5693593 https://reactome.org/PathwayBrowser/#/R-GGA-5693593 D-loop extension by DNA polymerases IEA Gallus gallus A0A1L1RUB9 R-GGA-6782208 https://reactome.org/PathwayBrowser/#/R-GGA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Gallus gallus A0A1L1RUB9 R-GGA-6782211 https://reactome.org/PathwayBrowser/#/R-GGA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Gallus gallus A0A1L1RUB9 R-GGA-6782227 https://reactome.org/PathwayBrowser/#/R-GGA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Gallus gallus A0A1L1RUB9 R-GGA-69053 https://reactome.org/PathwayBrowser/#/R-GGA-69053 RFC binding displaces Pol Alpha IEA Gallus gallus A0A1L1RUB9 R-GGA-69063 https://reactome.org/PathwayBrowser/#/R-GGA-69063 Loading of PCNA - Sliding Clamp Formation IEA Gallus gallus A0A1L1RUB9 R-GGA-69068 https://reactome.org/PathwayBrowser/#/R-GGA-69068 RFC dissociates after sliding clamp formation IEA Gallus gallus A0A1L1RUB9 R-GGA-9668902 https://reactome.org/PathwayBrowser/#/R-GGA-9668902 Formation of the CTF18-RFC(7s) complex IEA Gallus gallus A0A1L1RUD3 R-GGA-6791222 https://reactome.org/PathwayBrowser/#/R-GGA-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Gallus gallus A0A1L1RUD3 R-GGA-6791227 https://reactome.org/PathwayBrowser/#/R-GGA-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Gallus gallus A0A1L1RUE2 R-GGA-5617828 https://reactome.org/PathwayBrowser/#/R-GGA-5617828 TRIP11:IFT20 dissociates IEA Gallus gallus A0A1L1RUE2 R-GGA-5624949 https://reactome.org/PathwayBrowser/#/R-GGA-5624949 Assembly of the anterograde IFT train IEA Gallus gallus A0A1L1RUE2 R-GGA-5625416 https://reactome.org/PathwayBrowser/#/R-GGA-5625416 Anterograde IFT IEA Gallus gallus A0A1L1RUE2 R-GGA-5625426 https://reactome.org/PathwayBrowser/#/R-GGA-5625426 Retrograde IFT IEA Gallus gallus A0A1L1RUE7 R-GGA-1168640 https://reactome.org/PathwayBrowser/#/R-GGA-1168640 Ubiquitinated IkB is degraded IEA Gallus gallus A0A1L1RUE7 R-GGA-1234159 https://reactome.org/PathwayBrowser/#/R-GGA-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Gallus gallus A0A1L1RUE7 R-GGA-1236970 https://reactome.org/PathwayBrowser/#/R-GGA-1236970 Proteasomal clevage of exogenous antigen (26S proteasome catalyst) IEA Gallus gallus A0A1L1RUE7 R-GGA-1504193 https://reactome.org/PathwayBrowser/#/R-GGA-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-174058 https://reactome.org/PathwayBrowser/#/R-GGA-174058 Degradation of multiubiquitinated Cdh1 IEA Gallus gallus A0A1L1RUE7 R-GGA-174105 https://reactome.org/PathwayBrowser/#/R-GGA-174105 Degradation of multiubiquitinated cell cycle proteins IEA Gallus gallus A0A1L1RUE7 R-GGA-174202 https://reactome.org/PathwayBrowser/#/R-GGA-174202 Degradation of multiubiquitinated Securin IEA Gallus gallus A0A1L1RUE7 R-GGA-174255 https://reactome.org/PathwayBrowser/#/R-GGA-174255 Degradation multiubiquitinated Cyclin A IEA Gallus gallus A0A1L1RUE7 R-GGA-187574 https://reactome.org/PathwayBrowser/#/R-GGA-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-188191 https://reactome.org/PathwayBrowser/#/R-GGA-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Gallus gallus A0A1L1RUE7 R-GGA-209061 https://reactome.org/PathwayBrowser/#/R-GGA-209061 Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex IEA Gallus gallus A0A1L1RUE7 R-GGA-2130282 https://reactome.org/PathwayBrowser/#/R-GGA-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-264458 https://reactome.org/PathwayBrowser/#/R-GGA-264458 Proteasome mediated degradation of COP1 IEA Gallus gallus A0A1L1RUE7 R-GGA-353125 https://reactome.org/PathwayBrowser/#/R-GGA-353125 26S proteosome degrades ODC holoenzyme complex IEA Gallus gallus A0A1L1RUE7 R-GGA-3640874 https://reactome.org/PathwayBrowser/#/R-GGA-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-450466 https://reactome.org/PathwayBrowser/#/R-GGA-450466 AUF1:mRNA complex is destroyed IEA Gallus gallus A0A1L1RUE7 R-GGA-4608855 https://reactome.org/PathwayBrowser/#/R-GGA-4608855 PRICKLE1 is degraded by the proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-4641256 https://reactome.org/PathwayBrowser/#/R-GGA-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-5362448 https://reactome.org/PathwayBrowser/#/R-GGA-5362448 Hh C-terminal fragments are degraded by the proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-5607724 https://reactome.org/PathwayBrowser/#/R-GGA-5607724 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex IEA Gallus gallus A0A1L1RUE7 R-GGA-5610754 https://reactome.org/PathwayBrowser/#/R-GGA-5610754 GLI3 is partially degraded by the proteasome to yield the GLI3 repressor IEA Gallus gallus A0A1L1RUE7 R-GGA-5610758 https://reactome.org/PathwayBrowser/#/R-GGA-5610758 GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP IEA Gallus gallus A0A1L1RUE7 R-GGA-5610760 https://reactome.org/PathwayBrowser/#/R-GGA-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Gallus gallus A0A1L1RUE7 R-GGA-5635854 https://reactome.org/PathwayBrowser/#/R-GGA-5635854 GLI2,3 are degraded by the proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-5635868 https://reactome.org/PathwayBrowser/#/R-GGA-5635868 ub-GLI is degraded by the proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-5658430 https://reactome.org/PathwayBrowser/#/R-GGA-5658430 NF1 is degraded by the proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-5665854 https://reactome.org/PathwayBrowser/#/R-GGA-5665854 ADRM1:26S proteaseome binds UCHL5 IEA Gallus gallus A0A1L1RUE7 R-GGA-5665871 https://reactome.org/PathwayBrowser/#/R-GGA-5665871 ADRM1 binds 26S proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-5668481 https://reactome.org/PathwayBrowser/#/R-GGA-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Gallus gallus A0A1L1RUE7 R-GGA-5668520 https://reactome.org/PathwayBrowser/#/R-GGA-5668520 26Sproteasome degrades K48polyUb-NIK IEA Gallus gallus A0A1L1RUE7 R-GGA-5687112 https://reactome.org/PathwayBrowser/#/R-GGA-5687112 MAPK6 is degraded by the 26S proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-5689539 https://reactome.org/PathwayBrowser/#/R-GGA-5689539 ADRM1:26S proteaseome binds USP14 IEA Gallus gallus A0A1L1RUE7 R-GGA-68825 https://reactome.org/PathwayBrowser/#/R-GGA-68825 Ubiquitinated geminin is degraded by the proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-68948 https://reactome.org/PathwayBrowser/#/R-GGA-68948 Ubiquitinated Orc1 is degraded by the proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-69016 https://reactome.org/PathwayBrowser/#/R-GGA-69016 Ubiquitinated Cdc6 is degraded by the proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-69600 https://reactome.org/PathwayBrowser/#/R-GGA-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Gallus gallus A0A1L1RUE7 R-GGA-75825 https://reactome.org/PathwayBrowser/#/R-GGA-75825 Proteasome mediated degradation of Cyclin D1 IEA Gallus gallus A0A1L1RUE7 R-GGA-8850992 https://reactome.org/PathwayBrowser/#/R-GGA-8850992 Proteasome degrades polyubiquitinated PTEN IEA Gallus gallus A0A1L1RUE7 R-GGA-8854044 https://reactome.org/PathwayBrowser/#/R-GGA-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Gallus gallus A0A1L1RUE7 R-GGA-8854071 https://reactome.org/PathwayBrowser/#/R-GGA-8854071 Proteasome-mediated degradation of PolyUb-FBXL7 IEA Gallus gallus A0A1L1RUE7 R-GGA-8866553 https://reactome.org/PathwayBrowser/#/R-GGA-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-8932355 https://reactome.org/PathwayBrowser/#/R-GGA-8932355 26S proteasome degrades Ub-NFE2L2 IEA Gallus gallus A0A1L1RUE7 R-GGA-8939801 https://reactome.org/PathwayBrowser/#/R-GGA-8939801 26S proteasome degrades PolyUb-RUNX2 IEA Gallus gallus A0A1L1RUE7 R-GGA-8952408 https://reactome.org/PathwayBrowser/#/R-GGA-8952408 Polyubiquitinated RUNX3 is degraded by the proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-8956140 https://reactome.org/PathwayBrowser/#/R-GGA-8956140 NEDD8 and UBD bind NUB1 and the 26S proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-8956184 https://reactome.org/PathwayBrowser/#/R-GGA-8956184 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates IEA Gallus gallus A0A1L1RUE7 R-GGA-8957265 https://reactome.org/PathwayBrowser/#/R-GGA-8957265 26S proteasome degrades TP73 polyubiquitinated by ITCH IEA Gallus gallus A0A1L1RUE7 R-GGA-9755303 https://reactome.org/PathwayBrowser/#/R-GGA-9755303 26S proteasome degrades HIFalpha IEA Gallus gallus A0A1L1RUE7 R-GGA-9755306 https://reactome.org/PathwayBrowser/#/R-GGA-9755306 ub UBXN7 is degraded by the 26S proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-9762096 https://reactome.org/PathwayBrowser/#/R-GGA-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Gallus gallus A0A1L1RUE7 R-GGA-983150 https://reactome.org/PathwayBrowser/#/R-GGA-983150 Proteasomal cleavage of substrate IEA Gallus gallus A0A1L1RUE7 R-GGA-9907919 https://reactome.org/PathwayBrowser/#/R-GGA-9907919 Formation of the preholoproteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-9907940 https://reactome.org/PathwayBrowser/#/R-GGA-9907940 Formation of the preholothymoproteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-9907941 https://reactome.org/PathwayBrowser/#/R-GGA-9907941 Fromation of the preholoimmunoproteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-9908721 https://reactome.org/PathwayBrowser/#/R-GGA-9908721 Formation of the PA28gamma-20S proteasome IEA Gallus gallus A0A1L1RUE7 R-GGA-9912636 https://reactome.org/PathwayBrowser/#/R-GGA-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Gallus gallus A0A1L1RUE7 R-GGA-9934893 https://reactome.org/PathwayBrowser/#/R-GGA-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 IEA Gallus gallus A0A1L1RUH7 R-GGA-5577050 https://reactome.org/PathwayBrowser/#/R-GGA-5577050 AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region IEA Gallus gallus A0A1L1RUH7 R-GGA-5577237 https://reactome.org/PathwayBrowser/#/R-GGA-5577237 KCNH2:KCNE transport K+ from cytosol to extracellular region IEA Gallus gallus A0A1L1RUH7 R-GGA-9613264 https://reactome.org/PathwayBrowser/#/R-GGA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Gallus gallus A0A1L1RUI8 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1L1RUM0 R-GGA-114284 https://reactome.org/PathwayBrowser/#/R-GGA-114284 Release of Cytochrome c from mitochondria IEA Gallus gallus A0A1L1RUM0 R-GGA-449058 https://reactome.org/PathwayBrowser/#/R-GGA-449058 Interleukin-1 family are secreted IEA Gallus gallus A0A1L1RUM0 R-GGA-6798745 https://reactome.org/PathwayBrowser/#/R-GGA-6798745 Exocytosis of tertiary granule lumen proteins IEA Gallus gallus A0A1L1RUM0 R-GGA-6798749 https://reactome.org/PathwayBrowser/#/R-GGA-6798749 Exocytosis of specific granule lumen proteins IEA Gallus gallus A0A1L1RUM0 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1L1RUM0 R-GGA-6805981 https://reactome.org/PathwayBrowser/#/R-GGA-6805981 HMGB1 release from cells IEA Gallus gallus A0A1L1RUM0 R-GGA-9647619 https://reactome.org/PathwayBrowser/#/R-GGA-9647619 GSDMD forms ring‐shaped oligomers IEA Gallus gallus A0A1L1RUM0 R-GGA-9647631 https://reactome.org/PathwayBrowser/#/R-GGA-9647631 GSDMD (1-275) binds PIPs IEA Gallus gallus A0A1L1RUM0 R-GGA-9647643 https://reactome.org/PathwayBrowser/#/R-GGA-9647643 GSDMD (1-275) binds bacterial cardiolipin IEA Gallus gallus A0A1L1RUM0 R-GGA-9647645 https://reactome.org/PathwayBrowser/#/R-GGA-9647645 GSDMD oligomerizes into arc-, slit-shaped structures IEA Gallus gallus A0A1L1RUM0 R-GGA-9686088 https://reactome.org/PathwayBrowser/#/R-GGA-9686088 CASP3 cleaves GSDMD IEA Gallus gallus A0A1L1RUM0 R-GGA-9693324 https://reactome.org/PathwayBrowser/#/R-GGA-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Gallus gallus A0A1L1RUM0 R-GGA-9710101 https://reactome.org/PathwayBrowser/#/R-GGA-9710101 CASP4, CASP5 cleave GSDMD IEA Gallus gallus A0A1L1RUM0 R-GGA-9710353 https://reactome.org/PathwayBrowser/#/R-GGA-9710353 GSDMD (1-275) binds cardiolipin IEA Gallus gallus A0A1L1RUM0 R-GGA-9716258 https://reactome.org/PathwayBrowser/#/R-GGA-9716258 Dimethyl fumarate modifies Cys191 in GSDMD IEA Gallus gallus A0A1L1RUM8 R-GGA-139893 https://reactome.org/PathwayBrowser/#/R-GGA-139893 Granzyme-B activates BID by cleavage IEA Gallus gallus A0A1L1RUM8 R-GGA-1433374 https://reactome.org/PathwayBrowser/#/R-GGA-1433374 Processing of SCF isoform 1 IEA Gallus gallus A0A1L1RUM8 R-GGA-1592316 https://reactome.org/PathwayBrowser/#/R-GGA-1592316 Initial activation of proMMP1 IEA Gallus gallus A0A1L1RUM8 R-GGA-1604722 https://reactome.org/PathwayBrowser/#/R-GGA-1604722 Activation of proMMP9 by proteases IEA Gallus gallus A0A1L1RUM8 R-GGA-173745 https://reactome.org/PathwayBrowser/#/R-GGA-173745 Factor D cleaves C3(H2O)-bound Factor B IEA Gallus gallus A0A1L1RUM8 R-GGA-183122 https://reactome.org/PathwayBrowser/#/R-GGA-183122 Factor D cleaves C3b-bound Factor B IEA Gallus gallus A0A1L1RUM8 R-GGA-2022383 https://reactome.org/PathwayBrowser/#/R-GGA-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus A0A1L1RUM8 R-GGA-2022411 https://reactome.org/PathwayBrowser/#/R-GGA-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus A0A1L1RUM8 R-GGA-3785684 https://reactome.org/PathwayBrowser/#/R-GGA-3785684 Fibronectin degradation by CTSG IEA Gallus gallus A0A1L1RUM8 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1L1RUM8 R-GGA-6813659 https://reactome.org/PathwayBrowser/#/R-GGA-6813659 ELANE, CTSG or PRTN3 binds bacteria IEA Gallus gallus A0A1L1RUM8 R-GGA-9710263 https://reactome.org/PathwayBrowser/#/R-GGA-9710263 GZMB cleaves GSDME IEA Gallus gallus A0A1L1RUN2 R-GGA-1222516 https://reactome.org/PathwayBrowser/#/R-GGA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Gallus gallus A0A1L1RUN2 R-GGA-74723 https://reactome.org/PathwayBrowser/#/R-GGA-74723 Endosome acidification IEA Gallus gallus A0A1L1RUN2 R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus A0A1L1RUN2 R-GGA-9639286 https://reactome.org/PathwayBrowser/#/R-GGA-9639286 RRAGC,D exchanges GTP for GDP IEA Gallus gallus A0A1L1RUN2 R-GGA-9640167 https://reactome.org/PathwayBrowser/#/R-GGA-9640167 RRAGA,B exchanges GDP for GTP IEA Gallus gallus A0A1L1RUN2 R-GGA-9640168 https://reactome.org/PathwayBrowser/#/R-GGA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Gallus gallus A0A1L1RUN2 R-GGA-9640175 https://reactome.org/PathwayBrowser/#/R-GGA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Gallus gallus A0A1L1RUN2 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus A0A1L1RUN2 R-GGA-9645598 https://reactome.org/PathwayBrowser/#/R-GGA-9645598 RRAGC,D hydrolyzes GTP IEA Gallus gallus A0A1L1RUN2 R-GGA-9645608 https://reactome.org/PathwayBrowser/#/R-GGA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Gallus gallus A0A1L1RUN2 R-GGA-9646468 https://reactome.org/PathwayBrowser/#/R-GGA-9646468 mTORC1 binds RHEB:GTP IEA Gallus gallus A0A1L1RUQ1 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1L1RUS1 R-GGA-9913330 https://reactome.org/PathwayBrowser/#/R-GGA-9913330 SGCG,SGCZ and SGCA, SGCE bind SGCB:SGCD IEA Gallus gallus A0A1L1RUS1 R-GGA-9913336 https://reactome.org/PathwayBrowser/#/R-GGA-9913336 SGC:DAG1:SSPN complex translocates to plasma membrane IEA Gallus gallus A0A1L1RUS1 R-GGA-9913338 https://reactome.org/PathwayBrowser/#/R-GGA-9913338 Sarcoglycan complex (SGC) translocates to the Golgi membrane IEA Gallus gallus A0A1L1RUS1 R-GGA-9913339 https://reactome.org/PathwayBrowser/#/R-GGA-9913339 Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC IEA Gallus gallus A0A1L1RUS3 R-GGA-432164 https://reactome.org/PathwayBrowser/#/R-GGA-432164 Ca2+ influx into the post-synaptic cell IEA Gallus gallus A0A1L1RUS3 R-GGA-438037 https://reactome.org/PathwayBrowser/#/R-GGA-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Gallus gallus A0A1L1RUS3 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1L1RUT1 R-GGA-6807872 https://reactome.org/PathwayBrowser/#/R-GGA-6807872 Active ARF recruits coatomer IEA Gallus gallus A0A1L1RUT1 R-GGA-6807877 https://reactome.org/PathwayBrowser/#/R-GGA-6807877 ARFGAPs stimulate ARF GTPase activity IEA Gallus gallus A0A1L1RUT1 R-GGA-6809003 https://reactome.org/PathwayBrowser/#/R-GGA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Gallus gallus A0A1L1RUT1 R-GGA-6809006 https://reactome.org/PathwayBrowser/#/R-GGA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Gallus gallus A0A1L1RUT1 R-GGA-6809011 https://reactome.org/PathwayBrowser/#/R-GGA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Gallus gallus A0A1L1RUT1 R-GGA-6811417 https://reactome.org/PathwayBrowser/#/R-GGA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Gallus gallus A0A1L1RUT1 R-GGA-6811418 https://reactome.org/PathwayBrowser/#/R-GGA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Gallus gallus A0A1L1RUT1 R-GGA-6811423 https://reactome.org/PathwayBrowser/#/R-GGA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Gallus gallus A0A1L1RUT1 R-GGA-6811426 https://reactome.org/PathwayBrowser/#/R-GGA-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Gallus gallus A0A1L1RUT2 R-GGA-1112666 https://reactome.org/PathwayBrowser/#/R-GGA-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Gallus gallus A0A1L1RUT2 R-GGA-166753 https://reactome.org/PathwayBrowser/#/R-GGA-166753 Conversion of C4 into C4a and C4b IEA Gallus gallus A0A1L1RUT2 R-GGA-166792 https://reactome.org/PathwayBrowser/#/R-GGA-166792 Conversion of C2 into C2a and C2b IEA Gallus gallus A0A1L1RUT2 R-GGA-173626 https://reactome.org/PathwayBrowser/#/R-GGA-173626 Activation of C1r IEA Gallus gallus A0A1L1RUT2 R-GGA-173631 https://reactome.org/PathwayBrowser/#/R-GGA-173631 Activation of C1s IEA Gallus gallus A0A1L1RUT2 R-GGA-1861621 https://reactome.org/PathwayBrowser/#/R-GGA-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Gallus gallus A0A1L1RUT2 R-GGA-199161 https://reactome.org/PathwayBrowser/#/R-GGA-199161 Fc gamma receptors interact with antigen-bound IgG IEA Gallus gallus A0A1L1RUT2 R-GGA-2029268 https://reactome.org/PathwayBrowser/#/R-GGA-2029268 Phosphorylation and activation of PLCG IEA Gallus gallus A0A1L1RUT2 R-GGA-2029270 https://reactome.org/PathwayBrowser/#/R-GGA-2029270 Recruitment of PLCgamma to membrane IEA Gallus gallus A0A1L1RUT2 R-GGA-2029271 https://reactome.org/PathwayBrowser/#/R-GGA-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1L1RUT2 R-GGA-2029272 https://reactome.org/PathwayBrowser/#/R-GGA-2029272 Release of PLCG from FCGR IEA Gallus gallus A0A1L1RUT2 R-GGA-2029273 https://reactome.org/PathwayBrowser/#/R-GGA-2029273 PI3K binds to p-6Y-SYK IEA Gallus gallus A0A1L1RUT2 R-GGA-2029451 https://reactome.org/PathwayBrowser/#/R-GGA-2029451 Activation of RAC1 by VAV IEA Gallus gallus A0A1L1RUT2 R-GGA-2029452 https://reactome.org/PathwayBrowser/#/R-GGA-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Gallus gallus A0A1L1RUT2 R-GGA-2029453 https://reactome.org/PathwayBrowser/#/R-GGA-2029453 Phosphorylation of VAV IEA Gallus gallus A0A1L1RUT2 R-GGA-2029455 https://reactome.org/PathwayBrowser/#/R-GGA-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Gallus gallus A0A1L1RUT2 R-GGA-2029457 https://reactome.org/PathwayBrowser/#/R-GGA-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Gallus gallus A0A1L1RUT2 R-GGA-2029458 https://reactome.org/PathwayBrowser/#/R-GGA-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Gallus gallus A0A1L1RUT2 R-GGA-2029459 https://reactome.org/PathwayBrowser/#/R-GGA-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Gallus gallus A0A1L1RUT2 R-GGA-2029467 https://reactome.org/PathwayBrowser/#/R-GGA-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Gallus gallus A0A1L1RUT2 R-GGA-2029476 https://reactome.org/PathwayBrowser/#/R-GGA-2029476 Role of myosins in phagosome formation IEA Gallus gallus A0A1L1RUT2 R-GGA-2197697 https://reactome.org/PathwayBrowser/#/R-GGA-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Gallus gallus A0A1L1RUT2 R-GGA-2203516 https://reactome.org/PathwayBrowser/#/R-GGA-2203516 Alpha-1-Microglobulin is cleaved IEA Gallus gallus A0A1L1RUT2 R-GGA-8852266 https://reactome.org/PathwayBrowser/#/R-GGA-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Gallus gallus A0A1L1RUT2 R-GGA-8852481 https://reactome.org/PathwayBrowser/#/R-GGA-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Gallus gallus A0A1L1RUT2 R-GGA-8858428 https://reactome.org/PathwayBrowser/#/R-GGA-8858428 FCAMR binds IgA IEA Gallus gallus A0A1L1RUT2 R-GGA-9021306 https://reactome.org/PathwayBrowser/#/R-GGA-9021306 C1-Inh binds and inactivates C1r, C1s IEA Gallus gallus A0A1L1RUT2 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus A0A1L1RUT2 R-GGA-9724685 https://reactome.org/PathwayBrowser/#/R-GGA-9724685 IgE binds omalizumab IEA Gallus gallus A0A1L1RUT2 R-GGA-983696 https://reactome.org/PathwayBrowser/#/R-GGA-983696 The Immunoglobulin of the BCR binds antigen IEA Gallus gallus A0A1L1RUT2 R-GGA-983700 https://reactome.org/PathwayBrowser/#/R-GGA-983700 SYK binds the activated BCR IEA Gallus gallus A0A1L1RUT2 R-GGA-983703 https://reactome.org/PathwayBrowser/#/R-GGA-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Gallus gallus A0A1L1RUT2 R-GGA-983707 https://reactome.org/PathwayBrowser/#/R-GGA-983707 SYK autophosphorylates at the activated BCR IEA Gallus gallus A0A1L1RUU9 R-GGA-3928640 https://reactome.org/PathwayBrowser/#/R-GGA-3928640 PAKs phosphorylate MLC IEA Gallus gallus A0A1L1RUU9 R-GGA-445699 https://reactome.org/PathwayBrowser/#/R-GGA-445699 ATP Hydrolysis By Myosin IEA Gallus gallus A0A1L1RUU9 R-GGA-445700 https://reactome.org/PathwayBrowser/#/R-GGA-445700 Myosin Binds ATP IEA Gallus gallus A0A1L1RUU9 R-GGA-445704 https://reactome.org/PathwayBrowser/#/R-GGA-445704 Calcium Binds Caldesmon IEA Gallus gallus A0A1L1RUU9 R-GGA-445705 https://reactome.org/PathwayBrowser/#/R-GGA-445705 Release Of ADP From Myosin IEA Gallus gallus A0A1L1RUU9 R-GGA-445813 https://reactome.org/PathwayBrowser/#/R-GGA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Gallus gallus A0A1L1RUU9 R-GGA-5668932 https://reactome.org/PathwayBrowser/#/R-GGA-5668932 PAK2 phosphorylates myosin regulatory light chain (MRLC) IEA Gallus gallus A0A1L1RUW7 R-GGA-73666 https://reactome.org/PathwayBrowser/#/R-GGA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Gallus gallus A0A1L1RUX6 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1L1RUY8 R-GGA-5685953 https://reactome.org/PathwayBrowser/#/R-GGA-5685953 SIRT6 deacetylates RBBP8 IEA Gallus gallus A0A1L1RV09 R-GGA-2424246 https://reactome.org/PathwayBrowser/#/R-GGA-2424246 Tenascins C, R, (X, N) bind lecticans IEA Gallus gallus A0A1L1RV09 R-GGA-2681681 https://reactome.org/PathwayBrowser/#/R-GGA-2681681 Tenascins C, R, (X, N) bind fibronectin matrix IEA Gallus gallus A0A1L1RV29 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1L1RV54 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1L1RVE1 R-GGA-5668414 https://reactome.org/PathwayBrowser/#/R-GGA-5668414 TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK IEA Gallus gallus A0A1L1RVE1 R-GGA-5668454 https://reactome.org/PathwayBrowser/#/R-GGA-5668454 K63polyUb-cIAP1,2 ubiquitinates TRAF3 IEA Gallus gallus A0A1L1RVE1 R-GGA-5668481 https://reactome.org/PathwayBrowser/#/R-GGA-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Gallus gallus A0A1L1RVE1 R-GGA-5668534 https://reactome.org/PathwayBrowser/#/R-GGA-5668534 cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK IEA Gallus gallus A0A1L1RVE1 R-GGA-5676589 https://reactome.org/PathwayBrowser/#/R-GGA-5676589 RANKL,sRANKL trimer binds RANK IEA Gallus gallus A0A1L1RVE1 R-GGA-5676592 https://reactome.org/PathwayBrowser/#/R-GGA-5676592 2xRANK binds RANKL,sRANKL trimer:RANK IEA Gallus gallus A0A1L1RVE1 R-GGA-5676595 https://reactome.org/PathwayBrowser/#/R-GGA-5676595 TRAFs bind RANK:RANKL IEA Gallus gallus A0A1L1RVE4 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1L1RVF4 R-GGA-983158 https://reactome.org/PathwayBrowser/#/R-GGA-983158 Trimming of peptides in ER IEA Gallus gallus A0A1L1RVJ6 R-GGA-176474 https://reactome.org/PathwayBrowser/#/R-GGA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Gallus gallus A0A1L1RVJ6 R-GGA-176585 https://reactome.org/PathwayBrowser/#/R-GGA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Gallus gallus A0A1L1RVR1 R-GGA-446130 https://reactome.org/PathwayBrowser/#/R-GGA-446130 Interleukin-1 receptor type 2 binds Interleukin 1 IEA Gallus gallus A0A1L1RVS8 R-GGA-211966 https://reactome.org/PathwayBrowser/#/R-GGA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Gallus gallus A0A1L1RVS8 R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus A0A1L1RVS8 R-GGA-211991 https://reactome.org/PathwayBrowser/#/R-GGA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Gallus gallus A0A1L1RVS8 R-GGA-2161890 https://reactome.org/PathwayBrowser/#/R-GGA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Gallus gallus A0A1L1RVS8 R-GGA-2161899 https://reactome.org/PathwayBrowser/#/R-GGA-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Gallus gallus A0A1L1RVS8 R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus A0A1L1RVS8 R-GGA-9915971 https://reactome.org/PathwayBrowser/#/R-GGA-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Gallus gallus A0A1L1RVS8 R-GGA-9915997 https://reactome.org/PathwayBrowser/#/R-GGA-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Gallus gallus A0A1L1RVT7 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1L1RVX4 R-GGA-141310 https://reactome.org/PathwayBrowser/#/R-GGA-141310 FASL:FAS Receptor Trimer:FADD complex binds procaspase-10 IEA Gallus gallus A0A1L1RVX4 R-GGA-141316 https://reactome.org/PathwayBrowser/#/R-GGA-141316 TRAIL:TRAIL-Receptor2 Trimer:FADD complex binds procaspase-10 IEA Gallus gallus A0A1L1RVZ0 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1L1RVZ0 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1L1RVZ0 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1L1RVZ0 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1L1RVZ0 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1L1RW02 R-GGA-195408 https://reactome.org/PathwayBrowser/#/R-GGA-195408 NRP-1 forms a ternary complex with VEGF165 and VEGFR1 IEA Gallus gallus A0A1L1RW02 R-GGA-399930 https://reactome.org/PathwayBrowser/#/R-GGA-399930 Activation of PAK by Rac1 IEA Gallus gallus A0A1L1RW02 R-GGA-399933 https://reactome.org/PathwayBrowser/#/R-GGA-399933 Sema3A binds Nrp-1 bound to PlexinA IEA Gallus gallus A0A1L1RW02 R-GGA-399939 https://reactome.org/PathwayBrowser/#/R-GGA-399939 Autophosphorylation of PAK IEA Gallus gallus A0A1L1RW02 R-GGA-399944 https://reactome.org/PathwayBrowser/#/R-GGA-399944 Phosphorylation of CRMPs by Cdk5 IEA Gallus gallus A0A1L1RW02 R-GGA-399947 https://reactome.org/PathwayBrowser/#/R-GGA-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Gallus gallus A0A1L1RW02 R-GGA-399951 https://reactome.org/PathwayBrowser/#/R-GGA-399951 Phosphorylation of CRMPs by GSK3beta IEA Gallus gallus A0A1L1RW02 R-GGA-399952 https://reactome.org/PathwayBrowser/#/R-GGA-399952 Phosphorylation of LIMK-1 by PAK IEA Gallus gallus A0A1L1RW32 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1L1RW32 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1L1RW32 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1L1RW32 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1L1RW32 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1L1RW35 R-GGA-77263 https://reactome.org/PathwayBrowser/#/R-GGA-77263 lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 IEA Gallus gallus A0A1L1RW35 R-GGA-77274 https://reactome.org/PathwayBrowser/#/R-GGA-77274 myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2 IEA Gallus gallus A0A1L1RW56 R-GGA-1971491 https://reactome.org/PathwayBrowser/#/R-GGA-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Gallus gallus A0A1L1RW86 R-GGA-6789310 https://reactome.org/PathwayBrowser/#/R-GGA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Gallus gallus A0A1L1RWF7 R-GGA-209828 https://reactome.org/PathwayBrowser/#/R-GGA-209828 Tryptophan is hydroxylated IEA Gallus gallus A0A1L1RWG9 R-GGA-6805546 https://reactome.org/PathwayBrowser/#/R-GGA-6805546 Keratin type I binds keratin type II IEA Gallus gallus A0A1L1RWG9 R-GGA-6805573 https://reactome.org/PathwayBrowser/#/R-GGA-6805573 Keratin type I/type II heterodimers form tetramers IEA Gallus gallus A0A1L1RWG9 R-GGA-6806610 https://reactome.org/PathwayBrowser/#/R-GGA-6806610 Keratin filament formation IEA Gallus gallus A0A1L1RWG9 R-GGA-6806613 https://reactome.org/PathwayBrowser/#/R-GGA-6806613 Keratin tetramers bind to form unit length filaments IEA Gallus gallus A0A1L1RWG9 R-GGA-6806629 https://reactome.org/PathwayBrowser/#/R-GGA-6806629 Formation of tonofilament bundles IEA Gallus gallus A0A1L1RWG9 R-GGA-6809393 https://reactome.org/PathwayBrowser/#/R-GGA-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Gallus gallus A0A1L1RWG9 R-GGA-6810357 https://reactome.org/PathwayBrowser/#/R-GGA-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Gallus gallus A0A1L1RWI9 R-GGA-111915 https://reactome.org/PathwayBrowser/#/R-GGA-111915 CAMK4 autophosphorylates IEA Gallus gallus A0A1L1RWW9 R-GGA-202722 https://reactome.org/PathwayBrowser/#/R-GGA-202722 CD48 binds CD244 IEA Gallus gallus A0A1L1RWX6 R-GGA-5690043 https://reactome.org/PathwayBrowser/#/R-GGA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus A0A1L1RWY1 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1L1RWY1 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1L1RWY1 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1L1RWY1 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1L1RWY1 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1L1RWY2 R-GGA-372480 https://reactome.org/PathwayBrowser/#/R-GGA-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] IEA Gallus gallus A0A1L1RX22 R-GGA-373791 https://reactome.org/PathwayBrowser/#/R-GGA-373791 Receptor CXCR1 binds CXCL6 and CXCL8 ligands IEA Gallus gallus A0A1L1RX22 R-GGA-373813 https://reactome.org/PathwayBrowser/#/R-GGA-373813 Receptor CXCR2 binds ligands CXCL1 to 7 IEA Gallus gallus A0A1L1RX22 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1L1RX22 R-GGA-6798745 https://reactome.org/PathwayBrowser/#/R-GGA-6798745 Exocytosis of tertiary granule lumen proteins IEA Gallus gallus A0A1L1RX22 R-GGA-6798749 https://reactome.org/PathwayBrowser/#/R-GGA-6798749 Exocytosis of specific granule lumen proteins IEA Gallus gallus A0A1L1RX22 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1L1RX22 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1L1RX26 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1L1RX26 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1L1RX26 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1L1RX26 R-GGA-9629946 https://reactome.org/PathwayBrowser/#/R-GGA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Gallus gallus A0A1L1RX38 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1L1RX38 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1L1RX38 R-GGA-76031 https://reactome.org/PathwayBrowser/#/R-GGA-76031 2 H2O2 => O2 + 2 H2O IEA Gallus gallus A0A1L1RX38 R-GGA-9033235 https://reactome.org/PathwayBrowser/#/R-GGA-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Gallus gallus A0A1L1RX38 R-GGA-9033236 https://reactome.org/PathwayBrowser/#/R-GGA-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Gallus gallus A0A1L1RX67 R-GGA-140978 https://reactome.org/PathwayBrowser/#/R-GGA-140978 TRADD:TRAF2:RIP1 binds FADD IEA Gallus gallus A0A1L1RX67 R-GGA-5357845 https://reactome.org/PathwayBrowser/#/R-GGA-5357845 K63polyUb-RIPK1 is deubiquitinated IEA Gallus gallus A0A1L1RX77 R-GGA-1878002 https://reactome.org/PathwayBrowser/#/R-GGA-1878002 XYLTs transfer Xyl to core protein IEA Gallus gallus A0A1L1RX77 R-GGA-1889955 https://reactome.org/PathwayBrowser/#/R-GGA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Gallus gallus A0A1L1RX77 R-GGA-1889981 https://reactome.org/PathwayBrowser/#/R-GGA-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Gallus gallus A0A1L1RX77 R-GGA-1971482 https://reactome.org/PathwayBrowser/#/R-GGA-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Gallus gallus A0A1L1RX77 R-GGA-1971483 https://reactome.org/PathwayBrowser/#/R-GGA-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Gallus gallus A0A1L1RX77 R-GGA-1971487 https://reactome.org/PathwayBrowser/#/R-GGA-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Gallus gallus A0A1L1RX77 R-GGA-1971491 https://reactome.org/PathwayBrowser/#/R-GGA-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Gallus gallus A0A1L1RX77 R-GGA-2018659 https://reactome.org/PathwayBrowser/#/R-GGA-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Gallus gallus A0A1L1RX77 R-GGA-2018682 https://reactome.org/PathwayBrowser/#/R-GGA-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Gallus gallus A0A1L1RX77 R-GGA-2022052 https://reactome.org/PathwayBrowser/#/R-GGA-2022052 Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS) IEA Gallus gallus A0A1L1RX77 R-GGA-2022056 https://reactome.org/PathwayBrowser/#/R-GGA-2022056 DSPG and CSPG translocate to the lysosome for degradation IEA Gallus gallus A0A1L1RX77 R-GGA-2022061 https://reactome.org/PathwayBrowser/#/R-GGA-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Gallus gallus A0A1L1RX77 R-GGA-2022063 https://reactome.org/PathwayBrowser/#/R-GGA-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Gallus gallus A0A1L1RX77 R-GGA-2022065 https://reactome.org/PathwayBrowser/#/R-GGA-2022065 DSPGs are secreted IEA Gallus gallus A0A1L1RX77 R-GGA-2022911 https://reactome.org/PathwayBrowser/#/R-GGA-2022911 CSPG is secreted IEA Gallus gallus A0A1L1RX77 R-GGA-2327909 https://reactome.org/PathwayBrowser/#/R-GGA-2327909 DCN binds collagen I, II, III, VI fibrils IEA Gallus gallus A0A1L1RX77 R-GGA-2534248 https://reactome.org/PathwayBrowser/#/R-GGA-2534248 DCN (decorin) degradation by MMP2, MMP3, MMP7 IEA Gallus gallus A0A1L1RX77 R-GGA-3828025 https://reactome.org/PathwayBrowser/#/R-GGA-3828025 DCN (decorin) degradation by MMP14 IEA Gallus gallus A0A1L1RX77 R-GGA-9632033 https://reactome.org/PathwayBrowser/#/R-GGA-9632033 CHSY1 transfers GalNAc to chondroitin IEA Gallus gallus A0A1L1RX77 R-GGA-9632034 https://reactome.org/PathwayBrowser/#/R-GGA-9632034 CHSY1 transfers GlcA to chondroitin IEA Gallus gallus A0A1L1RX89 R-GGA-5684006 https://reactome.org/PathwayBrowser/#/R-GGA-5684006 KPNA2 translocates NBN to the nucleus IEA Gallus gallus A0A1L1RX89 R-GGA-5684008 https://reactome.org/PathwayBrowser/#/R-GGA-5684008 NBN binds KPNA2 IEA Gallus gallus A0A1L1RXA3 R-GGA-5690319 https://reactome.org/PathwayBrowser/#/R-GGA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Gallus gallus A0A1L1RXA3 R-GGA-5690808 https://reactome.org/PathwayBrowser/#/R-GGA-5690808 UCHL3, SENP8 cleave NEDD8 IEA Gallus gallus A0A1L1RXA3 R-GGA-8853503 https://reactome.org/PathwayBrowser/#/R-GGA-8853503 UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin IEA Gallus gallus A0A1L1RXA3 R-GGA-8853514 https://reactome.org/PathwayBrowser/#/R-GGA-8853514 UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin IEA Gallus gallus A0A1L1RXA3 R-GGA-8951644 https://reactome.org/PathwayBrowser/#/R-GGA-8951644 Release of mature NEDD8 IEA Gallus gallus A0A1L1RXJ1 R-GGA-9825759 https://reactome.org/PathwayBrowser/#/R-GGA-9825759 MAPK-dependent phosphorylation of KARS IEA Gallus gallus A0A1L1RXR3 R-GGA-8855062 https://reactome.org/PathwayBrowser/#/R-GGA-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy IEA Gallus gallus A0A1L1RXR5 R-GGA-164651 https://reactome.org/PathwayBrowser/#/R-GGA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Gallus gallus A0A1L1RXR5 R-GGA-9837978 https://reactome.org/PathwayBrowser/#/R-GGA-9837978 LONP1 binds mitochondrial inner membrane proteins IEA Gallus gallus A0A1L1RXR5 R-GGA-9838004 https://reactome.org/PathwayBrowser/#/R-GGA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Gallus gallus A0A1L1RXR5 R-GGA-9906042 https://reactome.org/PathwayBrowser/#/R-GGA-9906042 TTC19 clears UQCRFS1 fragments from Complex III IEA Gallus gallus A0A1L1RXS4 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1L1RXS4 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1L1RXS4 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1L1RXS4 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1L1RXS4 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1L1RXS4 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1L1RXS4 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1L1RXW8 R-GGA-390593 https://reactome.org/PathwayBrowser/#/R-GGA-390593 ATP Hydrolysis By Myosin IEA Gallus gallus A0A1L1RXW8 R-GGA-390595 https://reactome.org/PathwayBrowser/#/R-GGA-390595 Calcium Binds Troponin-C IEA Gallus gallus A0A1L1RXW8 R-GGA-390597 https://reactome.org/PathwayBrowser/#/R-GGA-390597 Release Of ADP From Myosin IEA Gallus gallus A0A1L1RXW8 R-GGA-390598 https://reactome.org/PathwayBrowser/#/R-GGA-390598 Myosin Binds ATP IEA Gallus gallus A0A1L1RY04 R-GGA-164832 https://reactome.org/PathwayBrowser/#/R-GGA-164832 ATPase synthesizes ATP IEA Gallus gallus A0A1L1RY04 R-GGA-164834 https://reactome.org/PathwayBrowser/#/R-GGA-164834 Enzyme-bound ATP is released IEA Gallus gallus A0A1L1RY04 R-GGA-164840 https://reactome.org/PathwayBrowser/#/R-GGA-164840 ADP and Pi bind to ATPase IEA Gallus gallus A0A1L1RY04 R-GGA-8949580 https://reactome.org/PathwayBrowser/#/R-GGA-8949580 F1Fo ATP synthase dimerizes IEA Gallus gallus A0A1L1RY04 R-GGA-8986181 https://reactome.org/PathwayBrowser/#/R-GGA-8986181 PITRM1 proteolyzes mitochondrial targeting peptides (presequences) IEA Gallus gallus A0A1L1RY04 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1L1RY04 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1L1RY66 R-GGA-5610766 https://reactome.org/PathwayBrowser/#/R-GGA-5610766 The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base IEA Gallus gallus A0A1L1RY66 R-GGA-5610767 https://reactome.org/PathwayBrowser/#/R-GGA-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Gallus gallus A0A1L1RY66 R-GGA-5617816 https://reactome.org/PathwayBrowser/#/R-GGA-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Gallus gallus A0A1L1RY66 R-GGA-5626681 https://reactome.org/PathwayBrowser/#/R-GGA-5626681 Recruitment of transition zone proteins IEA Gallus gallus A0A1L1RY66 R-GGA-5638009 https://reactome.org/PathwayBrowser/#/R-GGA-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Gallus gallus A0A1L1RY89 R-GGA-6806877 https://reactome.org/PathwayBrowser/#/R-GGA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Gallus gallus A0A1L1RY95 R-GGA-5682629 https://reactome.org/PathwayBrowser/#/R-GGA-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Gallus gallus A0A1L1RY95 R-GGA-5682858 https://reactome.org/PathwayBrowser/#/R-GGA-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Gallus gallus A0A1L1RY95 R-GGA-5682863 https://reactome.org/PathwayBrowser/#/R-GGA-5682863 RNF168 binds DNA DSBs IEA Gallus gallus A0A1L1RY95 R-GGA-5683077 https://reactome.org/PathwayBrowser/#/R-GGA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Gallus gallus A0A1L1RY95 R-GGA-5683384 https://reactome.org/PathwayBrowser/#/R-GGA-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Gallus gallus A0A1L1RY95 R-GGA-5683385 https://reactome.org/PathwayBrowser/#/R-GGA-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Gallus gallus A0A1L1RY95 R-GGA-5683425 https://reactome.org/PathwayBrowser/#/R-GGA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Gallus gallus A0A1L1RY95 R-GGA-5683735 https://reactome.org/PathwayBrowser/#/R-GGA-5683735 CHEK2 is recruited to DNA DSBs IEA Gallus gallus A0A1L1RY95 R-GGA-5683801 https://reactome.org/PathwayBrowser/#/R-GGA-5683801 CHEK2 phosphorylates BRCA1 IEA Gallus gallus A0A1L1RY95 R-GGA-5684052 https://reactome.org/PathwayBrowser/#/R-GGA-5684052 PIAS4 SUMOylates MDC1 IEA Gallus gallus A0A1L1RY95 R-GGA-5686685 https://reactome.org/PathwayBrowser/#/R-GGA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Gallus gallus A0A1L1RY95 R-GGA-5686704 https://reactome.org/PathwayBrowser/#/R-GGA-5686704 Activated ATM phosphorylates DCLRE1C IEA Gallus gallus A0A1L1RY95 R-GGA-5686900 https://reactome.org/PathwayBrowser/#/R-GGA-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Gallus gallus A0A1L1RY95 R-GGA-5693551 https://reactome.org/PathwayBrowser/#/R-GGA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Gallus gallus A0A1L1RY95 R-GGA-5693566 https://reactome.org/PathwayBrowser/#/R-GGA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Gallus gallus A0A1L1RY95 R-GGA-6790487 https://reactome.org/PathwayBrowser/#/R-GGA-6790487 RNF111 ubiquitinates SUMOylated XPC IEA Gallus gallus A0A1L1RY95 R-GGA-69891 https://reactome.org/PathwayBrowser/#/R-GGA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Gallus gallus A0A1L1RY95 R-GGA-8938815 https://reactome.org/PathwayBrowser/#/R-GGA-8938815 RNF152 polyubiquitinates RRAGA IEA Gallus gallus A0A1L1RY95 R-GGA-8938829 https://reactome.org/PathwayBrowser/#/R-GGA-8938829 RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 IEA Gallus gallus A0A1L1RY95 R-GGA-8943003 https://reactome.org/PathwayBrowser/#/R-GGA-8943003 SHPRH polyubiquitinates monoubiquitinated PCNA IEA Gallus gallus A0A1L1RY95 R-GGA-8943007 https://reactome.org/PathwayBrowser/#/R-GGA-8943007 SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N IEA Gallus gallus A0A1L1RY95 R-GGA-9641096 https://reactome.org/PathwayBrowser/#/R-GGA-9641096 Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub IEA Gallus gallus A0A1L1RY95 R-GGA-9641111 https://reactome.org/PathwayBrowser/#/R-GGA-9641111 Parkin transfers Ub to misfolded proteins IEA Gallus gallus A0A1L1RY95 R-GGA-9641127 https://reactome.org/PathwayBrowser/#/R-GGA-9641127 Ub:misfolded proteins polymerize to PolyUb:misfolded proteins IEA Gallus gallus A0A1L1RY95 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1L1RY95 R-GGA-983152 https://reactome.org/PathwayBrowser/#/R-GGA-983152 Transfer of ubiquitin from E1 to E2 IEA Gallus gallus A0A1L1RY95 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1L1RY95 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1L1RYA2 R-GGA-6798745 https://reactome.org/PathwayBrowser/#/R-GGA-6798745 Exocytosis of tertiary granule lumen proteins IEA Gallus gallus A0A1L1RYA2 R-GGA-6798749 https://reactome.org/PathwayBrowser/#/R-GGA-6798749 Exocytosis of specific granule lumen proteins IEA Gallus gallus A0A1L1RYA2 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1L1RYA9 R-GGA-8847579 https://reactome.org/PathwayBrowser/#/R-GGA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Gallus gallus A0A1L1RYK0 R-GGA-164832 https://reactome.org/PathwayBrowser/#/R-GGA-164832 ATPase synthesizes ATP IEA Gallus gallus A0A1L1RYK0 R-GGA-164834 https://reactome.org/PathwayBrowser/#/R-GGA-164834 Enzyme-bound ATP is released IEA Gallus gallus A0A1L1RYK0 R-GGA-164840 https://reactome.org/PathwayBrowser/#/R-GGA-164840 ADP and Pi bind to ATPase IEA Gallus gallus A0A1L1RYK0 R-GGA-8949580 https://reactome.org/PathwayBrowser/#/R-GGA-8949580 F1Fo ATP synthase dimerizes IEA Gallus gallus A0A1L1RYK0 R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus A0A1L1RYK0 R-GGA-9838093 https://reactome.org/PathwayBrowser/#/R-GGA-9838093 LONP1 binds mitochondrial matrix proteins IEA Gallus gallus A0A1L1RYK7 R-GGA-139855 https://reactome.org/PathwayBrowser/#/R-GGA-139855 P2X1-mediated entry of Ca++ from plasma IEA Gallus gallus A0A1L1RYK7 R-GGA-419490 https://reactome.org/PathwayBrowser/#/R-GGA-419490 Binding of ATP to P2X receptors IEA Gallus gallus A0A1L1RYL5 R-GGA-1168640 https://reactome.org/PathwayBrowser/#/R-GGA-1168640 Ubiquitinated IkB is degraded IEA Gallus gallus A0A1L1RYL5 R-GGA-1234159 https://reactome.org/PathwayBrowser/#/R-GGA-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Gallus gallus A0A1L1RYL5 R-GGA-1236970 https://reactome.org/PathwayBrowser/#/R-GGA-1236970 Proteasomal clevage of exogenous antigen (26S proteasome catalyst) IEA Gallus gallus A0A1L1RYL5 R-GGA-1504193 https://reactome.org/PathwayBrowser/#/R-GGA-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-174058 https://reactome.org/PathwayBrowser/#/R-GGA-174058 Degradation of multiubiquitinated Cdh1 IEA Gallus gallus A0A1L1RYL5 R-GGA-174105 https://reactome.org/PathwayBrowser/#/R-GGA-174105 Degradation of multiubiquitinated cell cycle proteins IEA Gallus gallus A0A1L1RYL5 R-GGA-174202 https://reactome.org/PathwayBrowser/#/R-GGA-174202 Degradation of multiubiquitinated Securin IEA Gallus gallus A0A1L1RYL5 R-GGA-174255 https://reactome.org/PathwayBrowser/#/R-GGA-174255 Degradation multiubiquitinated Cyclin A IEA Gallus gallus A0A1L1RYL5 R-GGA-187574 https://reactome.org/PathwayBrowser/#/R-GGA-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-188191 https://reactome.org/PathwayBrowser/#/R-GGA-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Gallus gallus A0A1L1RYL5 R-GGA-209061 https://reactome.org/PathwayBrowser/#/R-GGA-209061 Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex IEA Gallus gallus A0A1L1RYL5 R-GGA-2130282 https://reactome.org/PathwayBrowser/#/R-GGA-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-264458 https://reactome.org/PathwayBrowser/#/R-GGA-264458 Proteasome mediated degradation of COP1 IEA Gallus gallus A0A1L1RYL5 R-GGA-353125 https://reactome.org/PathwayBrowser/#/R-GGA-353125 26S proteosome degrades ODC holoenzyme complex IEA Gallus gallus A0A1L1RYL5 R-GGA-3640874 https://reactome.org/PathwayBrowser/#/R-GGA-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-450466 https://reactome.org/PathwayBrowser/#/R-GGA-450466 AUF1:mRNA complex is destroyed IEA Gallus gallus A0A1L1RYL5 R-GGA-4608855 https://reactome.org/PathwayBrowser/#/R-GGA-4608855 PRICKLE1 is degraded by the proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-4641256 https://reactome.org/PathwayBrowser/#/R-GGA-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-5362448 https://reactome.org/PathwayBrowser/#/R-GGA-5362448 Hh C-terminal fragments are degraded by the proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-5607724 https://reactome.org/PathwayBrowser/#/R-GGA-5607724 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex IEA Gallus gallus A0A1L1RYL5 R-GGA-5610754 https://reactome.org/PathwayBrowser/#/R-GGA-5610754 GLI3 is partially degraded by the proteasome to yield the GLI3 repressor IEA Gallus gallus A0A1L1RYL5 R-GGA-5610758 https://reactome.org/PathwayBrowser/#/R-GGA-5610758 GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP IEA Gallus gallus A0A1L1RYL5 R-GGA-5610760 https://reactome.org/PathwayBrowser/#/R-GGA-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Gallus gallus A0A1L1RYL5 R-GGA-5635854 https://reactome.org/PathwayBrowser/#/R-GGA-5635854 GLI2,3 are degraded by the proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-5635868 https://reactome.org/PathwayBrowser/#/R-GGA-5635868 ub-GLI is degraded by the proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-5658430 https://reactome.org/PathwayBrowser/#/R-GGA-5658430 NF1 is degraded by the proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-5665854 https://reactome.org/PathwayBrowser/#/R-GGA-5665854 ADRM1:26S proteaseome binds UCHL5 IEA Gallus gallus A0A1L1RYL5 R-GGA-5665871 https://reactome.org/PathwayBrowser/#/R-GGA-5665871 ADRM1 binds 26S proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-5668481 https://reactome.org/PathwayBrowser/#/R-GGA-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Gallus gallus A0A1L1RYL5 R-GGA-5668520 https://reactome.org/PathwayBrowser/#/R-GGA-5668520 26Sproteasome degrades K48polyUb-NIK IEA Gallus gallus A0A1L1RYL5 R-GGA-5687112 https://reactome.org/PathwayBrowser/#/R-GGA-5687112 MAPK6 is degraded by the 26S proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-5689539 https://reactome.org/PathwayBrowser/#/R-GGA-5689539 ADRM1:26S proteaseome binds USP14 IEA Gallus gallus A0A1L1RYL5 R-GGA-68825 https://reactome.org/PathwayBrowser/#/R-GGA-68825 Ubiquitinated geminin is degraded by the proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-68948 https://reactome.org/PathwayBrowser/#/R-GGA-68948 Ubiquitinated Orc1 is degraded by the proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-69016 https://reactome.org/PathwayBrowser/#/R-GGA-69016 Ubiquitinated Cdc6 is degraded by the proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-69600 https://reactome.org/PathwayBrowser/#/R-GGA-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Gallus gallus A0A1L1RYL5 R-GGA-75825 https://reactome.org/PathwayBrowser/#/R-GGA-75825 Proteasome mediated degradation of Cyclin D1 IEA Gallus gallus A0A1L1RYL5 R-GGA-8850992 https://reactome.org/PathwayBrowser/#/R-GGA-8850992 Proteasome degrades polyubiquitinated PTEN IEA Gallus gallus A0A1L1RYL5 R-GGA-8854044 https://reactome.org/PathwayBrowser/#/R-GGA-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Gallus gallus A0A1L1RYL5 R-GGA-8854071 https://reactome.org/PathwayBrowser/#/R-GGA-8854071 Proteasome-mediated degradation of PolyUb-FBXL7 IEA Gallus gallus A0A1L1RYL5 R-GGA-8866553 https://reactome.org/PathwayBrowser/#/R-GGA-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-8932355 https://reactome.org/PathwayBrowser/#/R-GGA-8932355 26S proteasome degrades Ub-NFE2L2 IEA Gallus gallus A0A1L1RYL5 R-GGA-8939801 https://reactome.org/PathwayBrowser/#/R-GGA-8939801 26S proteasome degrades PolyUb-RUNX2 IEA Gallus gallus A0A1L1RYL5 R-GGA-8952408 https://reactome.org/PathwayBrowser/#/R-GGA-8952408 Polyubiquitinated RUNX3 is degraded by the proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-8956140 https://reactome.org/PathwayBrowser/#/R-GGA-8956140 NEDD8 and UBD bind NUB1 and the 26S proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-8956184 https://reactome.org/PathwayBrowser/#/R-GGA-8956184 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates IEA Gallus gallus A0A1L1RYL5 R-GGA-8957265 https://reactome.org/PathwayBrowser/#/R-GGA-8957265 26S proteasome degrades TP73 polyubiquitinated by ITCH IEA Gallus gallus A0A1L1RYL5 R-GGA-9755303 https://reactome.org/PathwayBrowser/#/R-GGA-9755303 26S proteasome degrades HIFalpha IEA Gallus gallus A0A1L1RYL5 R-GGA-9755306 https://reactome.org/PathwayBrowser/#/R-GGA-9755306 ub UBXN7 is degraded by the 26S proteasome IEA Gallus gallus A0A1L1RYL5 R-GGA-9762096 https://reactome.org/PathwayBrowser/#/R-GGA-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Gallus gallus A0A1L1RYL5 R-GGA-983150 https://reactome.org/PathwayBrowser/#/R-GGA-983150 Proteasomal cleavage of substrate IEA Gallus gallus A0A1L1RYL5 R-GGA-9907948 https://reactome.org/PathwayBrowser/#/R-GGA-9907948 PSMC3 binds PSMC6 IEA Gallus gallus A0A1L1RYL5 R-GGA-9907965 https://reactome.org/PathwayBrowser/#/R-GGA-9907965 PSMD9 binds PSMC3:PSMC6 IEA Gallus gallus A0A1L1RYL5 R-GGA-9908026 https://reactome.org/PathwayBrowser/#/R-GGA-9908026 Formation of the 19S regulatory particle precursor IEA Gallus gallus A0A1L1RYL5 R-GGA-9934893 https://reactome.org/PathwayBrowser/#/R-GGA-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 IEA Gallus gallus A0A1L1RYL6 R-GGA-202703 https://reactome.org/PathwayBrowser/#/R-GGA-202703 CD47 binds SIRP IEA Gallus gallus A0A1L1RYL6 R-GGA-391151 https://reactome.org/PathwayBrowser/#/R-GGA-391151 p-4Y-SIRPA:CD47:SKAP2 binds FYB IEA Gallus gallus A0A1L1RYL6 R-GGA-391152 https://reactome.org/PathwayBrowser/#/R-GGA-391152 p-4Y-SIRPA:CD47 binds PTK2B IEA Gallus gallus A0A1L1RYL6 R-GGA-391153 https://reactome.org/PathwayBrowser/#/R-GGA-391153 p-4Y-SIRPA:CD47 binds GRB2-1 IEA Gallus gallus A0A1L1RYL6 R-GGA-391155 https://reactome.org/PathwayBrowser/#/R-GGA-391155 SIRPA binds SFTPA oligomer, SFTPD oligomer IEA Gallus gallus A0A1L1RYL6 R-GGA-391157 https://reactome.org/PathwayBrowser/#/R-GGA-391157 p-4Y-SIRPA:CD47 binds SKAP2 IEA Gallus gallus A0A1L1RYL6 R-GGA-391158 https://reactome.org/PathwayBrowser/#/R-GGA-391158 SIRP alpha binds CD47 IEA Gallus gallus A0A1L1RYL6 R-GGA-391168 https://reactome.org/PathwayBrowser/#/R-GGA-391168 SIRP gamma binds CD47 IEA Gallus gallus A0A1L1RYL6 R-GGA-6798743 https://reactome.org/PathwayBrowser/#/R-GGA-6798743 Exocytosis of secretory granule membrane proteins IEA Gallus gallus A0A1L1RYL6 R-GGA-6798747 https://reactome.org/PathwayBrowser/#/R-GGA-6798747 Exocytosis of tertiary granule membrane proteins IEA Gallus gallus A0A1L1RYL6 R-GGA-6800426 https://reactome.org/PathwayBrowser/#/R-GGA-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Gallus gallus A0A1L1RYS1 R-GGA-388828 https://reactome.org/PathwayBrowser/#/R-GGA-388828 PD-1 binds B7DC and B7H1 IEA Gallus gallus A0A1L1RYS1 R-GGA-389758 https://reactome.org/PathwayBrowser/#/R-GGA-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Gallus gallus A0A1L1RYS1 R-GGA-389759 https://reactome.org/PathwayBrowser/#/R-GGA-389759 Interaction of SHP-1 or SHP-2 with phospho PD-1 IEA Gallus gallus A0A1L1RYS1 R-GGA-389762 https://reactome.org/PathwayBrowser/#/R-GGA-389762 Phosphorylation of PD-1 IEA Gallus gallus A0A1L1RYS1 R-GGA-9679421 https://reactome.org/PathwayBrowser/#/R-GGA-9679421 PDCD1 binds PDCD1 inhibitors IEA Gallus gallus A0A1L1RYT6 R-GGA-9021068 https://reactome.org/PathwayBrowser/#/R-GGA-9021068 PalmS-ESRs bind CAVs IEA Gallus gallus A0A1L1RYT6 R-GGA-9021079 https://reactome.org/PathwayBrowser/#/R-GGA-9021079 PalmS-ESRs:CAVs translocate to plasma membrane IEA Gallus gallus A0A1L1RYU0 R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus A0A1L1RYV3 R-GGA-2130706 https://reactome.org/PathwayBrowser/#/R-GGA-2130706 MHC class II antigen processing IEA Gallus gallus A0A1L1RYY0 R-GGA-5690043 https://reactome.org/PathwayBrowser/#/R-GGA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus A0A1L1RYY0 R-GGA-8873794 https://reactome.org/PathwayBrowser/#/R-GGA-8873794 PCTP binds PC IEA Gallus gallus A0A1L1RZ59 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus A0A1L1RZ60 R-GGA-1605768 https://reactome.org/PathwayBrowser/#/R-GGA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Gallus gallus A0A1L1RZ60 R-GGA-4084994 https://reactome.org/PathwayBrowser/#/R-GGA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus A0A1L1RZ69 R-GGA-194678 https://reactome.org/PathwayBrowser/#/R-GGA-194678 CYP51A1 demethylates LNSOL IEA Gallus gallus A0A1L1RZ81 R-GGA-1592371 https://reactome.org/PathwayBrowser/#/R-GGA-1592371 Initial activation of proMMP3 IEA Gallus gallus A0A1L1RZ81 R-GGA-1602458 https://reactome.org/PathwayBrowser/#/R-GGA-1602458 Activation of proMMP10 IEA Gallus gallus A0A1L1RZ81 R-GGA-1604722 https://reactome.org/PathwayBrowser/#/R-GGA-1604722 Activation of proMMP9 by proteases IEA Gallus gallus A0A1L1RZ94 R-GGA-9014449 https://reactome.org/PathwayBrowser/#/R-GGA-9014449 RHOG binds effectors at the plasma membrane IEA Gallus gallus A0A1L1RZA6 R-GGA-975040 https://reactome.org/PathwayBrowser/#/R-GGA-975040 KRAB-ZNF / KAP Interaction IEA Gallus gallus A0A1L1RZA6 R-GGA-9842833 https://reactome.org/PathwayBrowser/#/R-GGA-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Gallus gallus A0A1L1RZA6 R-GGA-9842835 https://reactome.org/PathwayBrowser/#/R-GGA-9842835 KRAB-ZFP binds retroelement DNA in chromatin IEA Gallus gallus A0A1L1RZA6 R-GGA-9842839 https://reactome.org/PathwayBrowser/#/R-GGA-9842839 ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1L1RZA6 R-GGA-9843978 https://reactome.org/PathwayBrowser/#/R-GGA-9843978 CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin IEA Gallus gallus A0A1L1RZH6 R-GGA-5693347 https://reactome.org/PathwayBrowser/#/R-GGA-5693347 CRYM reduces P2C to PPCA IEA Gallus gallus A0A1L1RZK1 R-GGA-5694071 https://reactome.org/PathwayBrowser/#/R-GGA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Gallus gallus A0A1L1RZM9 R-GGA-198824 https://reactome.org/PathwayBrowser/#/R-GGA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Gallus gallus A0A1L1RZM9 R-GGA-6798751 https://reactome.org/PathwayBrowser/#/R-GGA-6798751 Exocytosis of azurophil granule lumen proteins IEA Gallus gallus A0A1L1RZM9 R-GGA-8936442 https://reactome.org/PathwayBrowser/#/R-GGA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Gallus gallus A0A1L1RZN8 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1L1RZN8 R-GGA-444523 https://reactome.org/PathwayBrowser/#/R-GGA-444523 CXCR5 binds CXCL13 IEA Gallus gallus A0A1L1RZN8 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1L1RZN8 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1L1RZP2 R-GGA-6807206 https://reactome.org/PathwayBrowser/#/R-GGA-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Gallus gallus A0A1L1RZP2 R-GGA-8873946 https://reactome.org/PathwayBrowser/#/R-GGA-8873946 OTUD3 deubiquitinates PTEN IEA Gallus gallus A0A1L1RZP5 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus A0A1L1RZP5 R-GGA-174786 https://reactome.org/PathwayBrowser/#/R-GGA-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex IEA Gallus gallus A0A1L1RZP5 R-GGA-2002460 https://reactome.org/PathwayBrowser/#/R-GGA-2002460 P4HB binds Collagen chains IEA Gallus gallus A0A1L1RZP5 R-GGA-264997 https://reactome.org/PathwayBrowser/#/R-GGA-264997 P4HB mediates disulfide bond formation in Proinsulin IEA Gallus gallus A0A1L1RZP5 R-GGA-3341296 https://reactome.org/PathwayBrowser/#/R-GGA-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Gallus gallus A0A1L1RZP5 R-GGA-5358336 https://reactome.org/PathwayBrowser/#/R-GGA-5358336 P4HB forms mixed disulphides with Hh precursors IEA Gallus gallus A0A1L1RZP5 R-GGA-5358340 https://reactome.org/PathwayBrowser/#/R-GGA-5358340 Autoproteolytic cleavage of Hh precursors IEA Gallus gallus A0A1L1RZP5 R-GGA-8866329 https://reactome.org/PathwayBrowser/#/R-GGA-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Gallus gallus A0A1L1RZP5 R-GGA-8948234 https://reactome.org/PathwayBrowser/#/R-GGA-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Gallus gallus A0A1L1RZP5 R-GGA-8950113 https://reactome.org/PathwayBrowser/#/R-GGA-8950113 IL12A binds IL12B IEA Gallus gallus A0A1L1RZP5 R-GGA-8950456 https://reactome.org/PathwayBrowser/#/R-GGA-8950456 IL12B dimerizes IEA Gallus gallus A0A1L1RZP5 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1L1RZP5 R-GGA-9737780 https://reactome.org/PathwayBrowser/#/R-GGA-9737780 MTTP binds lomitapide IEA Gallus gallus A0A1L1RZP5 R-GGA-9817575 https://reactome.org/PathwayBrowser/#/R-GGA-9817575 ERO1B oxidizes P4HB IEA Gallus gallus A0A1L1RZR0 R-GGA-5689544 https://reactome.org/PathwayBrowser/#/R-GGA-5689544 UCHL5 binds INO80 complex IEA Gallus gallus A0A1L1RZR0 R-GGA-5691006 https://reactome.org/PathwayBrowser/#/R-GGA-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site IEA Gallus gallus A0A1L1RZR2 R-GGA-3371422 https://reactome.org/PathwayBrowser/#/R-GGA-3371422 ATP hydrolysis by HSP70 IEA Gallus gallus A0A1L1RZR2 R-GGA-3371503 https://reactome.org/PathwayBrowser/#/R-GGA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Gallus gallus A0A1L1RZR2 R-GGA-3371590 https://reactome.org/PathwayBrowser/#/R-GGA-3371590 HSP70 binds to HSP40:nascent protein IEA Gallus gallus A0A1L1RZR2 R-GGA-9857090 https://reactome.org/PathwayBrowser/#/R-GGA-9857090 Reactive oxygen species oxidize DNAJA1 IEA Gallus gallus A0A1L1RZU7 R-GGA-430028 https://reactome.org/PathwayBrowser/#/R-GGA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Gallus gallus A0A1L1RZU7 R-GGA-450488 https://reactome.org/PathwayBrowser/#/R-GGA-450488 BRF1 Complex recruits RNA degradation activities IEA Gallus gallus A0A1L1RZU7 R-GGA-6791222 https://reactome.org/PathwayBrowser/#/R-GGA-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Gallus gallus A0A1L1RZU7 R-GGA-9933575 https://reactome.org/PathwayBrowser/#/R-GGA-9933575 MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome IEA Gallus gallus A0A1L1RZU7 R-GGA-9934522 https://reactome.org/PathwayBrowser/#/R-GGA-9934522 NEXT:ZC3H18:CBCA:m7GpppN-RNA binds the RNA exosome IEA Gallus gallus A0A1L1RZV0 R-GGA-5682629 https://reactome.org/PathwayBrowser/#/R-GGA-5682629 HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 IEA Gallus gallus A0A1L1RZV0 R-GGA-5682858 https://reactome.org/PathwayBrowser/#/R-GGA-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Gallus gallus A0A1L1RZV0 R-GGA-5682863 https://reactome.org/PathwayBrowser/#/R-GGA-5682863 RNF168 binds DNA DSBs IEA Gallus gallus A0A1L1RZV0 R-GGA-5683077 https://reactome.org/PathwayBrowser/#/R-GGA-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Gallus gallus A0A1L1RZV0 R-GGA-5683384 https://reactome.org/PathwayBrowser/#/R-GGA-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Gallus gallus A0A1L1RZV0 R-GGA-5683385 https://reactome.org/PathwayBrowser/#/R-GGA-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Gallus gallus A0A1L1RZV0 R-GGA-5683425 https://reactome.org/PathwayBrowser/#/R-GGA-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Gallus gallus A0A1L1RZV0 R-GGA-5683735 https://reactome.org/PathwayBrowser/#/R-GGA-5683735 CHEK2 is recruited to DNA DSBs IEA Gallus gallus A0A1L1RZV0 R-GGA-5683801 https://reactome.org/PathwayBrowser/#/R-GGA-5683801 CHEK2 phosphorylates BRCA1 IEA Gallus gallus A0A1L1RZV0 R-GGA-5684052 https://reactome.org/PathwayBrowser/#/R-GGA-5684052 PIAS4 SUMOylates MDC1 IEA Gallus gallus A0A1L1RZV0 R-GGA-5686685 https://reactome.org/PathwayBrowser/#/R-GGA-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Gallus gallus A0A1L1RZV0 R-GGA-5686704 https://reactome.org/PathwayBrowser/#/R-GGA-5686704 Activated ATM phosphorylates DCLRE1C IEA Gallus gallus A0A1L1RZV0 R-GGA-5686900 https://reactome.org/PathwayBrowser/#/R-GGA-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Gallus gallus A0A1L1RZV0 R-GGA-5693551 https://reactome.org/PathwayBrowser/#/R-GGA-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Gallus gallus A0A1L1RZV0 R-GGA-5693566 https://reactome.org/PathwayBrowser/#/R-GGA-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Gallus gallus A0A1L1RZV0 R-GGA-6790487 https://reactome.org/PathwayBrowser/#/R-GGA-6790487 RNF111 ubiquitinates SUMOylated XPC IEA Gallus gallus A0A1L1RZV0 R-GGA-69891 https://reactome.org/PathwayBrowser/#/R-GGA-69891 Phosphorylation and activation of CHEK2 by ATM IEA Gallus gallus A0A1L1RZV0 R-GGA-8943003 https://reactome.org/PathwayBrowser/#/R-GGA-8943003 SHPRH polyubiquitinates monoubiquitinated PCNA IEA Gallus gallus A0A1L1RZV0 R-GGA-8943007 https://reactome.org/PathwayBrowser/#/R-GGA-8943007 SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N IEA Gallus gallus A0A1L1RZV0 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1L1RZV0 R-GGA-983152 https://reactome.org/PathwayBrowser/#/R-GGA-983152 Transfer of ubiquitin from E1 to E2 IEA Gallus gallus A0A1L1RZV0 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1L1RZV0 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1L1RZW5 R-GGA-76056 https://reactome.org/PathwayBrowser/#/R-GGA-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Gallus gallus A0A1L1RZW5 R-GGA-83803 https://reactome.org/PathwayBrowser/#/R-GGA-83803 Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex IEA Gallus gallus A0A1L1RZW5 R-GGA-83805 https://reactome.org/PathwayBrowser/#/R-GGA-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Gallus gallus A0A1L1RZX6 R-GGA-374787 https://reactome.org/PathwayBrowser/#/R-GGA-374787 GPCR neuropeptide receptor binds neuropeptides B and W IEA Gallus gallus A0A1L1RZX6 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1L1RZX6 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1L1RZX6 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1L1S072 R-GGA-8952618 https://reactome.org/PathwayBrowser/#/R-GGA-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1L1S072 R-GGA-8952620 https://reactome.org/PathwayBrowser/#/R-GGA-8952620 NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1L1S072 R-GGA-8955241 https://reactome.org/PathwayBrowser/#/R-GGA-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Gallus gallus A0A1L1S072 R-GGA-8956040 https://reactome.org/PathwayBrowser/#/R-GGA-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Gallus gallus A0A1L1S072 R-GGA-8956200 https://reactome.org/PathwayBrowser/#/R-GGA-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Gallus gallus A0A1L1S072 R-GGA-983140 https://reactome.org/PathwayBrowser/#/R-GGA-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Gallus gallus A0A1L1S072 R-GGA-983147 https://reactome.org/PathwayBrowser/#/R-GGA-983147 Release of E3 from polyubiquitinated substrate IEA Gallus gallus A0A1L1S072 R-GGA-983156 https://reactome.org/PathwayBrowser/#/R-GGA-983156 Polyubiquitination of substrate IEA Gallus gallus A0A1L1S072 R-GGA-983157 https://reactome.org/PathwayBrowser/#/R-GGA-983157 Interaction of E3 with substrate and E2-Ub complex IEA Gallus gallus A0A1L1S091 R-GGA-5672972 https://reactome.org/PathwayBrowser/#/R-GGA-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Gallus gallus A0A1L1S091 R-GGA-5675417 https://reactome.org/PathwayBrowser/#/R-GGA-5675417 PEBP1 binds activated RAF1 IEA Gallus gallus A0A1L1S0A4 R-GGA-373741 https://reactome.org/PathwayBrowser/#/R-GGA-373741 SDK2 homophillic interaction IEA Gallus gallus A0A1L1S0D5 R-GGA-1222516 https://reactome.org/PathwayBrowser/#/R-GGA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Gallus gallus A0A1L1S0D5 R-GGA-6799350 https://reactome.org/PathwayBrowser/#/R-GGA-6799350 Exocytosis of specific granule membrane proteins IEA Gallus gallus A0A1L1S0D5 R-GGA-74723 https://reactome.org/PathwayBrowser/#/R-GGA-74723 Endosome acidification IEA Gallus gallus A0A1L1S0D5 R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus A0A1L1S0D5 R-GGA-9639286 https://reactome.org/PathwayBrowser/#/R-GGA-9639286 RRAGC,D exchanges GTP for GDP IEA Gallus gallus A0A1L1S0D5 R-GGA-9640167 https://reactome.org/PathwayBrowser/#/R-GGA-9640167 RRAGA,B exchanges GDP for GTP IEA Gallus gallus A0A1L1S0D5 R-GGA-9640168 https://reactome.org/PathwayBrowser/#/R-GGA-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Gallus gallus A0A1L1S0D5 R-GGA-9640175 https://reactome.org/PathwayBrowser/#/R-GGA-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Gallus gallus A0A1L1S0D5 R-GGA-9640195 https://reactome.org/PathwayBrowser/#/R-GGA-9640195 RRAGA,B hydrolyzes GTP IEA Gallus gallus A0A1L1S0D5 R-GGA-9645598 https://reactome.org/PathwayBrowser/#/R-GGA-9645598 RRAGC,D hydrolyzes GTP IEA Gallus gallus A0A1L1S0D5 R-GGA-9645608 https://reactome.org/PathwayBrowser/#/R-GGA-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Gallus gallus A0A1L1S0D5 R-GGA-9646468 https://reactome.org/PathwayBrowser/#/R-GGA-9646468 mTORC1 binds RHEB:GTP IEA Gallus gallus A0A1L1S0D7 R-GGA-5419261 https://reactome.org/PathwayBrowser/#/R-GGA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Gallus gallus A0A1L1S0D7 R-GGA-5419264 https://reactome.org/PathwayBrowser/#/R-GGA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Gallus gallus A0A1L1S0D7 R-GGA-5419271 https://reactome.org/PathwayBrowser/#/R-GGA-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Gallus gallus A0A1L1S0D7 R-GGA-5419273 https://reactome.org/PathwayBrowser/#/R-GGA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Gallus gallus A0A1L1S0D7 R-GGA-5419281 https://reactome.org/PathwayBrowser/#/R-GGA-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Gallus gallus A0A1L1S0D8 R-GGA-6803523 https://reactome.org/PathwayBrowser/#/R-GGA-6803523 PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA IEA Gallus gallus A0A1L1S0D8 R-GGA-72103 https://reactome.org/PathwayBrowser/#/R-GGA-72103 Formation of pre-mRNPs IEA Gallus gallus A0A1L1S0D8 R-GGA-9794542 https://reactome.org/PathwayBrowser/#/R-GGA-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Gallus gallus A0A1L1S0E6 R-GGA-1524182 https://reactome.org/PathwayBrowser/#/R-GGA-1524182 Activated PLC gamma dissociates from the PDGF receptor IEA Gallus gallus A0A1L1S0E6 R-GGA-1524186 https://reactome.org/PathwayBrowser/#/R-GGA-1524186 Phosphorylation of PLCgamma by PDGFR IEA Gallus gallus A0A1L1S0E6 R-GGA-186765 https://reactome.org/PathwayBrowser/#/R-GGA-186765 PLC-gamma binds to the active receptor IEA Gallus gallus A0A1L1S0E6 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus A0A1L1S0E6 R-GGA-186778 https://reactome.org/PathwayBrowser/#/R-GGA-186778 SHP2 binds to the active receptor IEA Gallus gallus A0A1L1S0E6 R-GGA-186780 https://reactome.org/PathwayBrowser/#/R-GGA-186780 PI3-kinase binds to the active receptor IEA Gallus gallus A0A1L1S0E6 R-GGA-186800 https://reactome.org/PathwayBrowser/#/R-GGA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Gallus gallus A0A1L1S0E6 R-GGA-186819 https://reactome.org/PathwayBrowser/#/R-GGA-186819 SH2 domain of Src binds to the active receptor IEA Gallus gallus A0A1L1S0E6 R-GGA-186826 https://reactome.org/PathwayBrowser/#/R-GGA-186826 GRB2:SOS1 complex binds to the active receptor IEA Gallus gallus A0A1L1S0E6 R-GGA-186834 https://reactome.org/PathwayBrowser/#/R-GGA-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Gallus gallus A0A1L1S0E6 R-GGA-2316434 https://reactome.org/PathwayBrowser/#/R-GGA-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Gallus gallus A0A1L1S0E6 R-GGA-380780 https://reactome.org/PathwayBrowser/#/R-GGA-380780 Activation of Src IEA Gallus gallus A0A1L1S0E6 R-GGA-380782 https://reactome.org/PathwayBrowser/#/R-GGA-380782 STAT binds to the active receptor IEA Gallus gallus A0A1L1S0E6 R-GGA-382052 https://reactome.org/PathwayBrowser/#/R-GGA-382052 p130Cas and C3G bind PDGFR bound Crk IEA Gallus gallus A0A1L1S0E6 R-GGA-382056 https://reactome.org/PathwayBrowser/#/R-GGA-382056 Crk binds to the active PDGF receptor IEA Gallus gallus A0A1L1S0E6 R-GGA-382058 https://reactome.org/PathwayBrowser/#/R-GGA-382058 Nck binds to the active PDGF receptor IEA Gallus gallus A0A1L1S0E6 R-GGA-389083 https://reactome.org/PathwayBrowser/#/R-GGA-389083 Autophosphorylation of PDGF alpha receptors IEA Gallus gallus A0A1L1S0E6 R-GGA-389086 https://reactome.org/PathwayBrowser/#/R-GGA-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Gallus gallus A0A1L1S0E6 R-GGA-5672965 https://reactome.org/PathwayBrowser/#/R-GGA-5672965 RAS GEFs promote RAS nucleotide exchange IEA Gallus gallus A0A1L1S0E6 R-GGA-8864036 https://reactome.org/PathwayBrowser/#/R-GGA-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Gallus gallus A0A1L1S0E6 R-GGA-9674093 https://reactome.org/PathwayBrowser/#/R-GGA-9674093 PDGFRs bind type I TKI IEA Gallus gallus A0A1L1S0E6 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus A0A1L1S0G0 R-GGA-6810233 https://reactome.org/PathwayBrowser/#/R-GGA-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Gallus gallus A0A1L1S0G0 R-GGA-6810235 https://reactome.org/PathwayBrowser/#/R-GGA-6810235 RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain IEA Gallus gallus A0A1L1S0G0 R-GGA-6810238 https://reactome.org/PathwayBrowser/#/R-GGA-6810238 RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) IEA Gallus gallus A0A1L1S0G0 R-GGA-6810239 https://reactome.org/PathwayBrowser/#/R-GGA-6810239 SNAPc binds PSE of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) IEA Gallus gallus A0A1L1S0G0 R-GGA-6814555 https://reactome.org/PathwayBrowser/#/R-GGA-6814555 Integrator complex processes the 3' end of snRNA IEA Gallus gallus A0A1L1S0G0 R-GGA-6814559 https://reactome.org/PathwayBrowser/#/R-GGA-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Gallus gallus A0A1L1S0G0 R-GGA-83791 https://reactome.org/PathwayBrowser/#/R-GGA-83791 Binding of SNAPc, Oct-1, and Staf to Type 3 Promoter IEA Gallus gallus A0A1L1S0G0 R-GGA-83793 https://reactome.org/PathwayBrowser/#/R-GGA-83793 Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex IEA Gallus gallus A0A1L1S0G0 R-GGA-83803 https://reactome.org/PathwayBrowser/#/R-GGA-83803 Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex IEA Gallus gallus A0A1L1S0G8 R-GGA-1675994 https://reactome.org/PathwayBrowser/#/R-GGA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Gallus gallus A0A1L1S0G8 R-GGA-1676203 https://reactome.org/PathwayBrowser/#/R-GGA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Gallus gallus A0A1L1S0G8 R-GGA-6809309 https://reactome.org/PathwayBrowser/#/R-GGA-6809309 MTMR6 binds MTMR9 IEA Gallus gallus A0A1L1S0G8 R-GGA-6809320 https://reactome.org/PathwayBrowser/#/R-GGA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Gallus gallus A0A1L1S0G8 R-GGA-6809325 https://reactome.org/PathwayBrowser/#/R-GGA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Gallus gallus A0A1L1S0H5 R-GGA-72180 https://reactome.org/PathwayBrowser/#/R-GGA-72180 Cleavage of mRNA at the 3'-end IEA Gallus gallus A0A1L1S0H7 R-GGA-3228469 https://reactome.org/PathwayBrowser/#/R-GGA-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Gallus gallus A0A1L1S0H7 R-GGA-3238999 https://reactome.org/PathwayBrowser/#/R-GGA-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 IEA Gallus gallus A0A1L1S0H7 R-GGA-450296 https://reactome.org/PathwayBrowser/#/R-GGA-450296 Phosphorylated MKK3/MKK6 migrates to nucleus IEA Gallus gallus A0A1L1S0H7 R-GGA-450333 https://reactome.org/PathwayBrowser/#/R-GGA-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Gallus gallus A0A1L1S0H7 R-GGA-450346 https://reactome.org/PathwayBrowser/#/R-GGA-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Gallus gallus A0A1L1S0H7 R-GGA-727819 https://reactome.org/PathwayBrowser/#/R-GGA-727819 TAK1 phosphorylates MKK6 IEA Gallus gallus A0A1L1S0H7 R-GGA-8877691 https://reactome.org/PathwayBrowser/#/R-GGA-8877691 MAP2K6 phosphorylates PIP4K2B IEA Gallus gallus A0A1L1S0H7 R-GGA-9836322 https://reactome.org/PathwayBrowser/#/R-GGA-9836322 p-PKR dimer phosphorylates MKK6 IEA Gallus gallus A0A1L1S0I3 R-GGA-8952289 https://reactome.org/PathwayBrowser/#/R-GGA-8952289 FAM20C phosphorylates FAM20C substrates IEA Gallus gallus A0A1L1S0M1 R-GGA-6798748 https://reactome.org/PathwayBrowser/#/R-GGA-6798748 Exocytosis of secretory granule lumen proteins IEA Gallus gallus A0A1L1S0M1 R-GGA-6800434 https://reactome.org/PathwayBrowser/#/R-GGA-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Gallus gallus A0A1L1S0P1 R-GGA-5687284 https://reactome.org/PathwayBrowser/#/R-GGA-5687284 DMBT1 binds SFTPD 12mer, SFTPAs IEA Gallus gallus A0A1L1S0P7 R-GGA-1632857 https://reactome.org/PathwayBrowser/#/R-GGA-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Gallus gallus A0A1L1S0P7 R-GGA-5665868 https://reactome.org/PathwayBrowser/#/R-GGA-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Gallus gallus A0A1L1S0P7 R-GGA-5672008 https://reactome.org/PathwayBrowser/#/R-GGA-5672008 Thr-180 of ULK1 is phosphorylated IEA Gallus gallus A0A1L1S0P7 R-GGA-5672010 https://reactome.org/PathwayBrowser/#/R-GGA-5672010 Active MTORC1 phosphorylates ULK1 IEA Gallus gallus A0A1L1S0P7 R-GGA-5672011 https://reactome.org/PathwayBrowser/#/R-GGA-5672011 p-AMPK:AMP binds the ULK complex IEA Gallus gallus A0A1L1S0P7 R-GGA-5672817 https://reactome.org/PathwayBrowser/#/R-GGA-5672817 Active MTORC1 binds the ULK1 complex IEA Gallus gallus A0A1L1S0P7 R-GGA-5673768 https://reactome.org/PathwayBrowser/#/R-GGA-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Gallus gallus A0A1L1S0P7 R-GGA-5675790 https://reactome.org/PathwayBrowser/#/R-GGA-5675790 MTORC1 dissociates from ULK complex IEA Gallus gallus A0A1L1S0P7 R-GGA-5675868 https://reactome.org/PathwayBrowser/#/R-GGA-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Gallus gallus A0A1L1S0P7 R-GGA-5679205 https://reactome.org/PathwayBrowser/#/R-GGA-5679205 ULK1 phosphorylates Beclin-1 IEA Gallus gallus A0A1L1S0P7 R-GGA-5679239 https://reactome.org/PathwayBrowser/#/R-GGA-5679239 ULK complex translocates to the ER IEA Gallus gallus A0A1L1S0P7 R-GGA-5683925 https://reactome.org/PathwayBrowser/#/R-GGA-5683925 ULK1 is dephosphorylated IEA Gallus gallus A0A1L1S0X5 R-GGA-1799332 https://reactome.org/PathwayBrowser/#/R-GGA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Gallus gallus A0A1L1S0X5 R-GGA-72671 https://reactome.org/PathwayBrowser/#/R-GGA-72671 eIF5B:GTP is hydrolyzed and released IEA Gallus gallus A0A1L1S0X5 R-GGA-72672 https://reactome.org/PathwayBrowser/#/R-GGA-72672 The 60S subunit joins the translation initiation complex IEA Gallus gallus A0A1L1S0X5 R-GGA-72673 https://reactome.org/PathwayBrowser/#/R-GGA-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Gallus gallus A0A1L1S0X5 R-GGA-927789 https://reactome.org/PathwayBrowser/#/R-GGA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Gallus gallus A0A1L1S0X5 R-GGA-927836 https://reactome.org/PathwayBrowser/#/R-GGA-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Gallus gallus A0A1L1S0X5 R-GGA-927889 https://reactome.org/PathwayBrowser/#/R-GGA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Gallus gallus A0A1L1S0Y9 R-GGA-1363328 https://reactome.org/PathwayBrowser/#/R-GGA-1363328 Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex IEA Gallus gallus A0A1L1S0Y9 R-GGA-1363331 https://reactome.org/PathwayBrowser/#/R-GGA-1363331 Ubiquitination of p130 (RBL2) by SCF (Skp2) IEA Gallus gallus A0A1L1S0Y9 R-GGA-187545 https://reactome.org/PathwayBrowser/#/R-GGA-187545 Association of Cks1 with SCF(Skp2) complex IEA Gallus gallus A0A1L1S0Y9 R-GGA-187552 https://reactome.org/PathwayBrowser/#/R-GGA-187552 Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex IEA Gallus gallus A0A1L1S0Y9 R-GGA-187574 https://reactome.org/PathwayBrowser/#/R-GGA-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Gallus gallus A0A1L1S0Y9 R-GGA-187575 https://reactome.org/PathwayBrowser/#/R-GGA-187575 Ubiquitination of phospho-p27/p21 IEA Gallus gallus A0A1L1S0Z2 R-GGA-548831 https://reactome.org/PathwayBrowser/#/R-GGA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Gallus gallus A0A1L1SQF6 R-MMU-9753027 https://reactome.org/PathwayBrowser/#/R-MMU-9753027 Rtp1s:Rtp2:underrepresented Olfactory Receptor translocates from the endoplasmic reticulum membrane to the plasma membrane TAS Mus musculus A0A1L1SQF6 R-MMU-9753035 https://reactome.org/PathwayBrowser/#/R-MMU-9753035 Rtp1s and Rtp2 bind underrepresented Olfactory Receptor TAS Mus musculus A0A1L1SUI3 R-MMU-198513 https://reactome.org/PathwayBrowser/#/R-MMU-198513 SLC7A4 exchanges G6P for Pi across the ER membrane IEA Mus musculus A0A1L1SVB5 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus A0A1L6UW65 R-DRE-9018794 https://reactome.org/PathwayBrowser/#/R-DRE-9018794 RHOV binds effectors at the plasma membrane IEA Danio rerio A0A1L6ZA08 R-SSC-481044 https://reactome.org/PathwayBrowser/#/R-SSC-481044 Surface deployment of platelet alpha granule membrane components IEA Sus scrofa A0A1L6ZA12 R-BTA-481044 https://reactome.org/PathwayBrowser/#/R-BTA-481044 Surface deployment of platelet alpha granule membrane components IEA Bos taurus A0A1L7HA09 R-GGA-374337 https://reactome.org/PathwayBrowser/#/R-GGA-374337 Apelin receptor binds to apelin IEA Gallus gallus A0A1L7HA09 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus A0A1L7HA09 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus A0A1L7HA09 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus A0A1L7NQ94 R-GGA-1297333 https://reactome.org/PathwayBrowser/#/R-GGA-1297333 Association of Acrosin Heavy and Light Chain IEA Gallus gallus A0A1L7NQ94 R-GGA-1297354 https://reactome.org/PathwayBrowser/#/R-GGA-1297354 Acrosin Cleavage IEA Gallus gallus A0A1L8FS35 R-XLA-9835799 https://reactome.org/PathwayBrowser/#/R-XLA-9835799 tfap2a binds the pax3 gene TAS Xenopus laevis A0A1L8FS35 R-XLA-9835813 https://reactome.org/PathwayBrowser/#/R-XLA-9835813 Expression of pax3 in the neural border TAS Xenopus laevis A0A1L8H1I9 R-NUL-9615968 https://reactome.org/PathwayBrowser/#/R-NUL-9615968 Transportin sequesters the Nup107-160 complex TAS Homo sapiens A0A1L8H1I9 R-NUL-9616174 https://reactome.org/PathwayBrowser/#/R-NUL-9616174 RAN:GTP binds transportin associated with Nup107-160 and displaces Nup107-160 TAS Homo sapiens A0A1L8H1I9 R-NUL-9616176 https://reactome.org/PathwayBrowser/#/R-NUL-9616176 RAN:GTP binds importin beta associated with nup107-160 and displaces nup107-160 TAS Xenopus laevis A0A1L8H1I9 R-XLA-9615967 https://reactome.org/PathwayBrowser/#/R-XLA-9615967 Importin beta sequesters the Nup107-160 complex TAS Xenopus laevis A0A1L8HU22 R-XLA-9636011 https://reactome.org/PathwayBrowser/#/R-XLA-9636011 neil3 resolves AP-ICLs TAS Xenopus laevis A0A1N7SYP3 R-CEL-9018766 https://reactome.org/PathwayBrowser/#/R-CEL-9018766 RHOU binds effectors at the plasma membrane IEA Caenorhabditis elegans A0A1N7SYP3 R-CEL-9018794 https://reactome.org/PathwayBrowser/#/R-CEL-9018794 RHOV binds effectors at the plasma membrane IEA Caenorhabditis elegans A0A1N7SYP5 R-CEL-2870221 https://reactome.org/PathwayBrowser/#/R-CEL-2870221 E-selectin binds E-selectin ligand IEA Caenorhabditis elegans A0A1N7SYP5 R-CEL-481009 https://reactome.org/PathwayBrowser/#/R-CEL-481009 Exocytosis of platelet dense granule content IEA Caenorhabditis elegans A0A1N7SYP5 R-CEL-481010 https://reactome.org/PathwayBrowser/#/R-CEL-481010 Surface deployment of platelet dense granule membrane components IEA Caenorhabditis elegans A0A1N7SYP5 R-CEL-481044 https://reactome.org/PathwayBrowser/#/R-CEL-481044 Surface deployment of platelet alpha granule membrane components IEA Caenorhabditis elegans A0A1N7SYP5 R-CEL-6798743 https://reactome.org/PathwayBrowser/#/R-CEL-6798743 Exocytosis of secretory granule membrane proteins IEA Caenorhabditis elegans A0A1N7SYP5 R-CEL-6800426 https://reactome.org/PathwayBrowser/#/R-CEL-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Caenorhabditis elegans A0A1N7SYP5 R-CEL-6809003 https://reactome.org/PathwayBrowser/#/R-CEL-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Caenorhabditis elegans A0A1N7SYP5 R-CEL-6809011 https://reactome.org/PathwayBrowser/#/R-CEL-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Caenorhabditis elegans A0A1N7SYS3 R-CEL-9865449 https://reactome.org/PathwayBrowser/#/R-CEL-9865449 Metallochaperone inserts Cu2+ into MT-CO1 IEA Caenorhabditis elegans A0A1N7SYW0 R-CEL-975389 https://reactome.org/PathwayBrowser/#/R-CEL-975389 GLRA:GLRB:Gly transports extracellular Cl- to cytosol IEA Caenorhabditis elegans A0A1N7SYW5 R-CEL-1363274 https://reactome.org/PathwayBrowser/#/R-CEL-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Caenorhabditis elegans A0A1N7SYW5 R-CEL-1363276 https://reactome.org/PathwayBrowser/#/R-CEL-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Caenorhabditis elegans A0A1N7SYW5 R-CEL-8856945 https://reactome.org/PathwayBrowser/#/R-CEL-8856945 PP2A methylation by LCMT1 IEA Caenorhabditis elegans A0A1N7SYW5 R-CEL-8856951 https://reactome.org/PathwayBrowser/#/R-CEL-8856951 PP2A demethylation by PPME1 IEA Caenorhabditis elegans A0A1N7SYX2 R-CEL-6793590 https://reactome.org/PathwayBrowser/#/R-CEL-6793590 LIPT2 transfers octanoyl group to GCSH IEA Caenorhabditis elegans A0A1N7SZG1 R-CEL-5626938 https://reactome.org/PathwayBrowser/#/R-CEL-5626938 Beta-catenin binds SOX proteins IEA Caenorhabditis elegans A0A1N7SZG1 R-CEL-5665608 https://reactome.org/PathwayBrowser/#/R-CEL-5665608 TCF:Beta-catenin binds SOX proteins IEA Caenorhabditis elegans A0A1P8YVD0 R-RNO-5617815 https://reactome.org/PathwayBrowser/#/R-RNO-5617815 BBSome binds RAB3IP IEA Rattus norvegicus A0A1P8YVD0 R-RNO-5624126 https://reactome.org/PathwayBrowser/#/R-RNO-5624126 ARL6:GTP and the BBSome bind ciliary cargo IEA Rattus norvegicus A0A1P8YVD0 R-RNO-5624127 https://reactome.org/PathwayBrowser/#/R-RNO-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Rattus norvegicus A0A1P8YVD0 R-RNO-5624129 https://reactome.org/PathwayBrowser/#/R-RNO-5624129 LZTFL1 binds the BBSome and prevents its traffic to the cilium IEA Rattus norvegicus A0A1S6M251 R-SSC-1964501 https://reactome.org/PathwayBrowser/#/R-SSC-1964501 Addition of galactose to Core 6 glycoprotein IEA Sus scrofa A0A1S6M251 R-SSC-2025723 https://reactome.org/PathwayBrowser/#/R-SSC-2025723 B4GALTs transfer Gal to the N-glycan precursor IEA Sus scrofa A0A1S6M251 R-SSC-2046265 https://reactome.org/PathwayBrowser/#/R-SSC-2046265 B4GALTs transfer Gal to the keratan chain IEA Sus scrofa A0A1S6M251 R-SSC-2046298 https://reactome.org/PathwayBrowser/#/R-SSC-2046298 B4GALTs transfer Gal to a branch of keratan IEA Sus scrofa A0A1S6M251 R-SSC-975919 https://reactome.org/PathwayBrowser/#/R-SSC-975919 Addition of galactose by beta 4-galactosyltransferases IEA Sus scrofa A0A1S6M251 R-SSC-9851347 https://reactome.org/PathwayBrowser/#/R-SSC-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Sus scrofa A0A1S7J0A8 R-CFA-166038 https://reactome.org/PathwayBrowser/#/R-CFA-166038 GPI-bound CD14 binds LPS IEA Canis familiaris A0A1S7J0A8 R-CFA-166041 https://reactome.org/PathwayBrowser/#/R-CFA-166041 Transfer of LPS onto TLR4 IEA Canis familiaris A0A1S7J0A8 R-CFA-166168 https://reactome.org/PathwayBrowser/#/R-CFA-166168 TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) IEA Canis familiaris A0A1S7J0A8 R-CFA-166175 https://reactome.org/PathwayBrowser/#/R-CFA-166175 TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) IEA Canis familiaris A0A1S7J0A8 R-CFA-166245 https://reactome.org/PathwayBrowser/#/R-CFA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Canis familiaris A0A1S7J0A8 R-CFA-166271 https://reactome.org/PathwayBrowser/#/R-CFA-166271 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 IEA Canis familiaris A0A1S7J0A8 R-CFA-168915 https://reactome.org/PathwayBrowser/#/R-CFA-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex IEA Canis familiaris A0A1S7J0A8 R-CFA-168921 https://reactome.org/PathwayBrowser/#/R-CFA-168921 TRIF:activated TLR3/TLR4 complex recruits RIP1 IEA Canis familiaris A0A1S7J0A8 R-CFA-169719 https://reactome.org/PathwayBrowser/#/R-CFA-169719 Secreted CD14 binds LPS IEA Canis familiaris A0A1S7J0A8 R-CFA-2201293 https://reactome.org/PathwayBrowser/#/R-CFA-2201293 Endocytosis of TLR4:LY96:LPS:CD14 IEA Canis familiaris A0A1S7J0A8 R-CFA-2201338 https://reactome.org/PathwayBrowser/#/R-CFA-2201338 TRAF3 binds TICAM1:activated TLR4 complex IEA Canis familiaris A0A1S7J0A8 R-CFA-2213017 https://reactome.org/PathwayBrowser/#/R-CFA-2213017 Auto-ubiquitination of TRAF3 IEA Canis familiaris A0A1S7J0A8 R-CFA-2559439 https://reactome.org/PathwayBrowser/#/R-CFA-2559439 CD14:LPS binds CR3 IEA Canis familiaris A0A1S7J0A8 R-CFA-2559568 https://reactome.org/PathwayBrowser/#/R-CFA-2559568 SARM binds TICAM1:TRAM:TLR4:LY96:LPS:CD14 IEA Canis familiaris A0A1S7J0A8 R-CFA-2562564 https://reactome.org/PathwayBrowser/#/R-CFA-2562564 Caspase-8 processing within TLR4 complex IEA Canis familiaris A0A1S7J0A8 R-CFA-2569057 https://reactome.org/PathwayBrowser/#/R-CFA-2569057 RIP3 binds TRIF to mediate necroptosis IEA Canis familiaris A0A1S7J0A8 R-CFA-450358 https://reactome.org/PathwayBrowser/#/R-CFA-450358 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation IEA Canis familiaris A0A1S7J0A8 R-CFA-5362486 https://reactome.org/PathwayBrowser/#/R-CFA-5362486 TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4 IEA Canis familiaris A0A1S7J0A8 R-CFA-5362500 https://reactome.org/PathwayBrowser/#/R-CFA-5362500 TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Canis familiaris A0A1S7J0A8 R-CFA-6798743 https://reactome.org/PathwayBrowser/#/R-CFA-6798743 Exocytosis of secretory granule membrane proteins IEA Canis familiaris A0A1S7J0A8 R-CFA-8869694 https://reactome.org/PathwayBrowser/#/R-CFA-8869694 oxPL binds CD14 IEA Canis familiaris A0A1S7J0A8 R-CFA-936947 https://reactome.org/PathwayBrowser/#/R-CFA-936947 Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex IEA Canis familiaris A0A1S7J0A8 R-CFA-936951 https://reactome.org/PathwayBrowser/#/R-CFA-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Canis familiaris A0A1S7J0A8 R-CFA-936952 https://reactome.org/PathwayBrowser/#/R-CFA-936952 Auto ubiquitination of TRAF6 bound to the activated TLR4 complex IEA Canis familiaris A0A1S7J0A8 R-CFA-936985 https://reactome.org/PathwayBrowser/#/R-CFA-936985 Activated TLR4:TICAM1 recruits TRAF6 IEA Canis familiaris A0A1S7J0A8 R-CFA-937029 https://reactome.org/PathwayBrowser/#/R-CFA-937029 IKBKG subunit of IKK complex binds polyubiquinated RIP1 IEA Canis familiaris A0A1S7J0A8 R-CFA-937075 https://reactome.org/PathwayBrowser/#/R-CFA-937075 Phosphorylated TAK1 leaves activated TLR receptor complex IEA Canis familiaris A0A1S7J0A8 R-CFA-9823904 https://reactome.org/PathwayBrowser/#/R-CFA-9823904 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Canis familiaris A0A1S7J0A8 R-CFA-9823906 https://reactome.org/PathwayBrowser/#/R-CFA-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Canis familiaris A0A1S7J0A8 R-CFA-9823910 https://reactome.org/PathwayBrowser/#/R-CFA-9823910 Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Canis familiaris A0A1S7J0A8 R-CFA-9823932 https://reactome.org/PathwayBrowser/#/R-CFA-9823932 Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Canis familiaris A0A1S7J0A8 R-CFA-9823934 https://reactome.org/PathwayBrowser/#/R-CFA-9823934 OPTN binds TBK1 within the activated TLR4 complex IEA Canis familiaris A0A1S7J0A8 R-CFA-9823939 https://reactome.org/PathwayBrowser/#/R-CFA-9823939 IKKε (IKBKE) is ubiquitinated within the activated TLR4 IEA Canis familiaris A0A1S7J0A8 R-CFA-9824882 https://reactome.org/PathwayBrowser/#/R-CFA-9824882 IKKε (IKBKE) is phosphorylated within the activated TLR4 complex IEA Canis familiaris A0A1T5HUK9 R-CEL-1632857 https://reactome.org/PathwayBrowser/#/R-CEL-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Caenorhabditis elegans A0A1T5HUK9 R-CEL-163664 https://reactome.org/PathwayBrowser/#/R-CEL-163664 AMP binds to gamma subunit of AMP kinase heterotrimer IEA Caenorhabditis elegans A0A1T5HUK9 R-CEL-200423 https://reactome.org/PathwayBrowser/#/R-CEL-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Caenorhabditis elegans A0A1T5HUK9 R-CEL-380930 https://reactome.org/PathwayBrowser/#/R-CEL-380930 Phosphorylated AMPK binds AMP IEA Caenorhabditis elegans A0A1T5HUK9 R-CEL-380949 https://reactome.org/PathwayBrowser/#/R-CEL-380949 AMPK is dephosphorylated IEA Caenorhabditis elegans A0A1T5HUK9 R-CEL-447074 https://reactome.org/PathwayBrowser/#/R-CEL-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Caenorhabditis elegans A0A1T5HUK9 R-CEL-5631941 https://reactome.org/PathwayBrowser/#/R-CEL-5631941 SESN1,2,3 bind AMPK IEA Caenorhabditis elegans A0A1T5HUK9 R-CEL-5665868 https://reactome.org/PathwayBrowser/#/R-CEL-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Caenorhabditis elegans A0A1T5HUK9 R-CEL-5672008 https://reactome.org/PathwayBrowser/#/R-CEL-5672008 Thr-180 of ULK1 is phosphorylated IEA Caenorhabditis elegans A0A1T5HUK9 R-CEL-5672011 https://reactome.org/PathwayBrowser/#/R-CEL-5672011 p-AMPK:AMP binds the ULK complex IEA Caenorhabditis elegans A0A1T5HUK9 R-CEL-5673768 https://reactome.org/PathwayBrowser/#/R-CEL-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Caenorhabditis elegans A0A1T5HUK9 R-CEL-5675868 https://reactome.org/PathwayBrowser/#/R-CEL-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Caenorhabditis elegans A0A1T5HUK9 R-CEL-5679205 https://reactome.org/PathwayBrowser/#/R-CEL-5679205 ULK1 phosphorylates Beclin-1 IEA Caenorhabditis elegans A0A1T5HUK9 R-CEL-5679239 https://reactome.org/PathwayBrowser/#/R-CEL-5679239 ULK complex translocates to the ER IEA Caenorhabditis elegans A0A1T5HUM0 R-CEL-203973 https://reactome.org/PathwayBrowser/#/R-CEL-203973 Vesicle budding IEA Caenorhabditis elegans A0A1T5HUM0 R-CEL-399711 https://reactome.org/PathwayBrowser/#/R-CEL-399711 Activation of Ca impermeable AMPA receptors IEA Caenorhabditis elegans A0A1T5HUM0 R-CEL-399712 https://reactome.org/PathwayBrowser/#/R-CEL-399712 Activation of Ca permeable AMPA receptors IEA Caenorhabditis elegans A0A1T5HUM0 R-CEL-420975 https://reactome.org/PathwayBrowser/#/R-CEL-420975 Ca impermeable AMPA receptor ligand binding IEA Caenorhabditis elegans A0A1T5HUM0 R-CEL-420977 https://reactome.org/PathwayBrowser/#/R-CEL-420977 Ca permeable AMPA receptor ligand binding IEA Caenorhabditis elegans A0A1T5HUM0 R-CEL-420980 https://reactome.org/PathwayBrowser/#/R-CEL-420980 Activation of Ca permeable AMPA receptors IEA Caenorhabditis elegans A0A1T5HUM0 R-CEL-438037 https://reactome.org/PathwayBrowser/#/R-CEL-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Caenorhabditis elegans A0A1T5HUM0 R-CEL-5694409 https://reactome.org/PathwayBrowser/#/R-CEL-5694409 Nucleotide exchange on RAB1 IEA Caenorhabditis elegans A0A1T5HUM0 R-CEL-5694417 https://reactome.org/PathwayBrowser/#/R-CEL-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Caenorhabditis elegans A0A1T5HUM0 R-CEL-5694418 https://reactome.org/PathwayBrowser/#/R-CEL-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Caenorhabditis elegans A0A1T5HUM0 R-CEL-5694439 https://reactome.org/PathwayBrowser/#/R-CEL-5694439 COPII coat binds TRAPPCII and RAB1:GDP IEA Caenorhabditis elegans A0A1T5HUM0 R-CEL-5694442 https://reactome.org/PathwayBrowser/#/R-CEL-5694442 CNIH2,3 bind GRIA1 IEA Caenorhabditis elegans A0A1T5HUM0 R-CEL-5694446 https://reactome.org/PathwayBrowser/#/R-CEL-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Caenorhabditis elegans A0A1T5HUM0 R-CEL-5694522 https://reactome.org/PathwayBrowser/#/R-CEL-5694522 Inner coat assembly and cargo binding IEA Caenorhabditis elegans A0A1T5HUM0 R-CEL-5694527 https://reactome.org/PathwayBrowser/#/R-CEL-5694527 Loss of SAR1B GTPase IEA Caenorhabditis elegans A0A1T5HUM0 R-CEL-8849881 https://reactome.org/PathwayBrowser/#/R-CEL-8849881 SALM2 associate with AMPA and NMDA receptors IEA Caenorhabditis elegans A0A1W2P6H7 R-MMU-975040 https://reactome.org/PathwayBrowser/#/R-MMU-975040 KRAB-ZNF / KAP Interaction IEA Mus musculus A0A1W2P728 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A1W2P739 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A1W2P7G7 R-MMU-975040 https://reactome.org/PathwayBrowser/#/R-MMU-975040 KRAB-ZNF / KAP Interaction IEA Mus musculus A0A1W2P7G7 R-MMU-9842833 https://reactome.org/PathwayBrowser/#/R-MMU-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Mus musculus A0A1W2P7N1 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A1W2P7T6 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A1W2P7U0 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A1W2P7W0 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A1W2P860 R-MMU-6809663 https://reactome.org/PathwayBrowser/#/R-MMU-6809663 Formation of hair keratin fibres IEA Mus musculus A0A1W2PPF3 R-HSA-9817941 https://reactome.org/PathwayBrowser/#/R-HSA-9817941 Expression of DUXB in the embryo TAS Homo sapiens A0A1W2Q5Z7 R-RNO-2046285 https://reactome.org/PathwayBrowser/#/R-RNO-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Rattus norvegicus A0A1W2Q5Z7 R-RNO-4084984 https://reactome.org/PathwayBrowser/#/R-RNO-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Rattus norvegicus A0A1W2Q5Z7 R-RNO-981497 https://reactome.org/PathwayBrowser/#/R-RNO-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Rattus norvegicus A0A1W2Q610 R-RNO-427570 https://reactome.org/PathwayBrowser/#/R-RNO-427570 Group 3 - Selective Cl- transport IEA Rattus norvegicus A0A1W2Q645 R-RNO-1614336 https://reactome.org/PathwayBrowser/#/R-RNO-1614336 SUMF2 binds SUMF1, inhibiting SUMF1-mediated activation of arylsulfatases IEA Rattus norvegicus A0A1W2Q645 R-RNO-1614362 https://reactome.org/PathwayBrowser/#/R-RNO-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Rattus norvegicus A0A1W2Q693 R-RNO-947499 https://reactome.org/PathwayBrowser/#/R-RNO-947499 Exchange of oxygen with sulfur in MoCo IEA Rattus norvegicus A0A1W2Q695 R-RNO-5358510 https://reactome.org/PathwayBrowser/#/R-RNO-5358510 MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA IEA Rattus norvegicus A0A1W2Q695 R-RNO-5358518 https://reactome.org/PathwayBrowser/#/R-RNO-5358518 MLH1:PMS2 makes single strand incision near 1-2 base mismatch IEA Rattus norvegicus A0A1W2Q695 R-RNO-5358525 https://reactome.org/PathwayBrowser/#/R-RNO-5358525 MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop IEA Rattus norvegicus A0A1W2Q695 R-RNO-5358597 https://reactome.org/PathwayBrowser/#/R-RNO-5358597 EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) IEA Rattus norvegicus A0A1W2Q695 R-RNO-5358599 https://reactome.org/PathwayBrowser/#/R-RNO-5358599 EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch IEA Rattus norvegicus A0A1W2Q695 R-RNO-5358912 https://reactome.org/PathwayBrowser/#/R-RNO-5358912 MSH2:MSH6 exchanges ADP for ATP IEA Rattus norvegicus A0A1W2Q695 R-RNO-5444516 https://reactome.org/PathwayBrowser/#/R-RNO-5444516 Formation of MSH2:MSH6 Complex IEA Rattus norvegicus A0A1W2Q6C2 R-RNO-5682709 https://reactome.org/PathwayBrowser/#/R-RNO-5682709 LGI4 binds ADAM22,23,11 IEA Rattus norvegicus A0A1W2Q6C2 R-RNO-5682826 https://reactome.org/PathwayBrowser/#/R-RNO-5682826 LGI1 binds ADAM11 IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-141409 https://reactome.org/PathwayBrowser/#/R-RNO-141409 Mad1 binds kinetochore IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-141422 https://reactome.org/PathwayBrowser/#/R-RNO-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-141431 https://reactome.org/PathwayBrowser/#/R-RNO-141431 MAD2 associates with the Mad1 kinetochore complex IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-141439 https://reactome.org/PathwayBrowser/#/R-RNO-141439 Release of activated MAD2 from kinetochores IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-1638803 https://reactome.org/PathwayBrowser/#/R-RNO-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-1638821 https://reactome.org/PathwayBrowser/#/R-RNO-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-2467809 https://reactome.org/PathwayBrowser/#/R-RNO-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-2467811 https://reactome.org/PathwayBrowser/#/R-RNO-2467811 Separation of sister chromatids IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-2468287 https://reactome.org/PathwayBrowser/#/R-RNO-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-2484822 https://reactome.org/PathwayBrowser/#/R-RNO-2484822 Kinetochore assembly IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-375302 https://reactome.org/PathwayBrowser/#/R-RNO-375302 Kinetochore capture of astral microtubules IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-5666129 https://reactome.org/PathwayBrowser/#/R-RNO-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-5666160 https://reactome.org/PathwayBrowser/#/R-RNO-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-5666169 https://reactome.org/PathwayBrowser/#/R-RNO-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-606287 https://reactome.org/PathwayBrowser/#/R-RNO-606287 RSF complex binds the centromere IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-606326 https://reactome.org/PathwayBrowser/#/R-RNO-606326 HJURP:CENPA complex localizes to the centromere IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-606349 https://reactome.org/PathwayBrowser/#/R-RNO-606349 Mis18 complex binds the centromere IEA Rattus norvegicus A0A1W2Q6F6 R-RNO-9648114 https://reactome.org/PathwayBrowser/#/R-RNO-9648114 EML4 recruits NUDC to mitotic spindle IEA Rattus norvegicus A0A1W2Q6G2 R-RNO-6797810 https://reactome.org/PathwayBrowser/#/R-RNO-6797810 PTPRD binds IL1RAPL1 IEA Rattus norvegicus A0A1W2Q6H2 R-RNO-419841 https://reactome.org/PathwayBrowser/#/R-RNO-419841 Light stimulates opsin receptors IEA Rattus norvegicus A0A1W2Q6H2 R-RNO-420883 https://reactome.org/PathwayBrowser/#/R-RNO-420883 Opsins act as GEFs for G alpha-t IEA Rattus norvegicus A0A1X7RC97 R-CEL-452036 https://reactome.org/PathwayBrowser/#/R-CEL-452036 arginine + H2O => ornithine + urea [ARG2] IEA Caenorhabditis elegans A0A1X7RC97 R-CEL-6798749 https://reactome.org/PathwayBrowser/#/R-CEL-6798749 Exocytosis of specific granule lumen proteins IEA Caenorhabditis elegans A0A1X7RC97 R-CEL-6798751 https://reactome.org/PathwayBrowser/#/R-CEL-6798751 Exocytosis of azurophil granule lumen proteins IEA Caenorhabditis elegans A0A1X7RC97 R-CEL-70569 https://reactome.org/PathwayBrowser/#/R-CEL-70569 arginine + H2O => ornithine + urea [ARG1] IEA Caenorhabditis elegans A0A1X7RC97 R-CEL-9838035 https://reactome.org/PathwayBrowser/#/R-CEL-9838035 CLPXP binds mitochondrial matrix proteins IEA Caenorhabditis elegans A0A1X7RC97 R-CEL-9838081 https://reactome.org/PathwayBrowser/#/R-CEL-9838081 LONP1 degrades mitochondrial matrix proteins IEA Caenorhabditis elegans A0A1X7RC97 R-CEL-9838093 https://reactome.org/PathwayBrowser/#/R-CEL-9838093 LONP1 binds mitochondrial matrix proteins IEA Caenorhabditis elegans A0A1X7RC97 R-CEL-9838289 https://reactome.org/PathwayBrowser/#/R-CEL-9838289 CLPXP degrades mitochondrial matrix proteins IEA Caenorhabditis elegans A0A1Y6D565 R-CFA-5662662 https://reactome.org/PathwayBrowser/#/R-CFA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Canis familiaris A0A1Y7VJN6 R-MMU-166753 https://reactome.org/PathwayBrowser/#/R-MMU-166753 Conversion of C4 into C4a and C4b IEA Mus musculus A0A1Y7VJN6 R-MMU-166792 https://reactome.org/PathwayBrowser/#/R-MMU-166792 Conversion of C2 into C2a and C2b IEA Mus musculus A0A1Y7VJN6 R-MMU-173626 https://reactome.org/PathwayBrowser/#/R-MMU-173626 Activation of C1r IEA Mus musculus A0A1Y7VJN6 R-MMU-173631 https://reactome.org/PathwayBrowser/#/R-MMU-173631 Activation of C1s IEA Mus musculus A0A1Y7VJN6 R-MMU-1861621 https://reactome.org/PathwayBrowser/#/R-MMU-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Mus musculus A0A1Y7VJN6 R-MMU-2029268 https://reactome.org/PathwayBrowser/#/R-MMU-2029268 Phosphorylation and activation of PLCG IEA Mus musculus A0A1Y7VJN6 R-MMU-2029270 https://reactome.org/PathwayBrowser/#/R-MMU-2029270 Recruitment of PLCgamma to membrane IEA Mus musculus A0A1Y7VJN6 R-MMU-2029271 https://reactome.org/PathwayBrowser/#/R-MMU-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Mus musculus A0A1Y7VJN6 R-MMU-2029272 https://reactome.org/PathwayBrowser/#/R-MMU-2029272 Release of PLCG from FCGR IEA Mus musculus A0A1Y7VJN6 R-MMU-2029273 https://reactome.org/PathwayBrowser/#/R-MMU-2029273 PI3K binds to p-6Y-SYK IEA Mus musculus A0A1Y7VJN6 R-MMU-2029451 https://reactome.org/PathwayBrowser/#/R-MMU-2029451 Activation of RAC1 by VAV IEA Mus musculus A0A1Y7VJN6 R-MMU-2029452 https://reactome.org/PathwayBrowser/#/R-MMU-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Mus musculus A0A1Y7VJN6 R-MMU-2029453 https://reactome.org/PathwayBrowser/#/R-MMU-2029453 Phosphorylation of VAV IEA Mus musculus A0A1Y7VJN6 R-MMU-2029455 https://reactome.org/PathwayBrowser/#/R-MMU-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Mus musculus A0A1Y7VJN6 R-MMU-2029457 https://reactome.org/PathwayBrowser/#/R-MMU-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Mus musculus A0A1Y7VJN6 R-MMU-2029458 https://reactome.org/PathwayBrowser/#/R-MMU-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Mus musculus A0A1Y7VJN6 R-MMU-2029459 https://reactome.org/PathwayBrowser/#/R-MMU-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Mus musculus A0A1Y7VJN6 R-MMU-2029467 https://reactome.org/PathwayBrowser/#/R-MMU-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Mus musculus A0A1Y7VJN6 R-MMU-2029476 https://reactome.org/PathwayBrowser/#/R-MMU-2029476 Role of myosins in phagosome formation IEA Mus musculus A0A1Y7VJN6 R-MMU-2197697 https://reactome.org/PathwayBrowser/#/R-MMU-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Mus musculus A0A1Y7VJN6 R-MMU-8852266 https://reactome.org/PathwayBrowser/#/R-MMU-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Mus musculus A0A1Y7VJN6 R-MMU-8852481 https://reactome.org/PathwayBrowser/#/R-MMU-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Mus musculus A0A1Y7VJN6 R-MMU-9021306 https://reactome.org/PathwayBrowser/#/R-MMU-9021306 C1-Inh binds and inactivates C1r, C1s IEA Mus musculus A0A1Y7VNZ0 R-MMU-8952638 https://reactome.org/PathwayBrowser/#/R-MMU-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Mus musculus A0A1Y7VNZ0 R-MMU-8952639 https://reactome.org/PathwayBrowser/#/R-MMU-8952639 NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex IEA Mus musculus A0A1Y7VNZ0 R-MMU-8955245 https://reactome.org/PathwayBrowser/#/R-MMU-8955245 CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus IEA Mus musculus A0A1Y7VNZ0 R-MMU-8955285 https://reactome.org/PathwayBrowser/#/R-MMU-8955285 COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex IEA Mus musculus A0A1Y7VNZ0 R-MMU-8956045 https://reactome.org/PathwayBrowser/#/R-MMU-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Mus musculus A0A1Z1CGZ4 R-DME-429094 https://reactome.org/PathwayBrowser/#/R-DME-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Drosophila melanogaster A0A1Z1CK50 R-DME-8866546 https://reactome.org/PathwayBrowser/#/R-DME-8866546 RNF5 and RNF185 ubiquitinate misfolded CFTR IEA Drosophila melanogaster A0A238UKL7 R-CEL-165026 https://reactome.org/PathwayBrowser/#/R-CEL-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Caenorhabditis elegans A0A238UKL7 R-CEL-2161500 https://reactome.org/PathwayBrowser/#/R-CEL-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Caenorhabditis elegans A0A238UKL7 R-CEL-374896 https://reactome.org/PathwayBrowser/#/R-CEL-374896 Uptake of Noradrenaline IEA Caenorhabditis elegans A0A238UKL7 R-CEL-374919 https://reactome.org/PathwayBrowser/#/R-CEL-374919 Noradrenaline clearance from the synaptic cleft IEA Caenorhabditis elegans A0A238UKL7 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans A0A238UKL7 R-CEL-549241 https://reactome.org/PathwayBrowser/#/R-CEL-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans A0A238UKL7 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans A0A238UKL7 R-CEL-549297 https://reactome.org/PathwayBrowser/#/R-CEL-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans A0A238UKL7 R-CEL-549304 https://reactome.org/PathwayBrowser/#/R-CEL-549304 OCT3 mediates renal clearance of organic cations IEA Caenorhabditis elegans A0A238UKL7 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans A0A238UKL7 R-CEL-561041 https://reactome.org/PathwayBrowser/#/R-CEL-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Caenorhabditis elegans A0A238UKL7 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans A0A238UKL7 R-CEL-561059 https://reactome.org/PathwayBrowser/#/R-CEL-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Caenorhabditis elegans A0A238UKL7 R-CEL-561072 https://reactome.org/PathwayBrowser/#/R-CEL-561072 OCT3 mediates renal uptake of organic cations IEA Caenorhabditis elegans A0A238UKL7 R-CEL-561253 https://reactome.org/PathwayBrowser/#/R-CEL-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Caenorhabditis elegans A0A238UKL7 R-CEL-9749583 https://reactome.org/PathwayBrowser/#/R-CEL-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Caenorhabditis elegans A0A238UKL7 R-CEL-9794523 https://reactome.org/PathwayBrowser/#/R-CEL-9794523 SLC22A1 transports Cipro into renal cell IEA Caenorhabditis elegans A0A238UKL7 R-CEL-9795207 https://reactome.org/PathwayBrowser/#/R-CEL-9795207 SLC22A1 transports Cipro into hepatic cell IEA Caenorhabditis elegans A0A286Y9C9 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio A0A286Y9C9 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio A0A286YCV9 R-MMU-2213248 https://reactome.org/PathwayBrowser/#/R-MMU-2213248 Transport of antigen loaded MHC II molecules to surface IEA Mus musculus A0A286YCV9 R-MMU-6811423 https://reactome.org/PathwayBrowser/#/R-MMU-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Mus musculus A0A286YCV9 R-MMU-6811426 https://reactome.org/PathwayBrowser/#/R-MMU-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Mus musculus A0A286YCV9 R-MMU-983259 https://reactome.org/PathwayBrowser/#/R-MMU-983259 Kinesins move along microtubules consuming ATP IEA Mus musculus A0A286YCV9 R-MMU-983266 https://reactome.org/PathwayBrowser/#/R-MMU-983266 Kinesins bind microtubules IEA Mus musculus A0A286YCX6 R-MMU-8877475 https://reactome.org/PathwayBrowser/#/R-MMU-8877475 TRAPPC complexes exchange GTP for GDP on RAB1 IEA Mus musculus A0A286YE47 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus A0A286ZFW3 R-SSC-481009 https://reactome.org/PathwayBrowser/#/R-SSC-481009 Exocytosis of platelet dense granule content IEA Sus scrofa A0A286ZHZ1 R-SSC-8869607 https://reactome.org/PathwayBrowser/#/R-SSC-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Sus scrofa A0A286ZHZ1 R-SSC-8869627 https://reactome.org/PathwayBrowser/#/R-SSC-8869627 NMRK2 phosphorylates NR to yield NMN IEA Sus scrofa A0A286ZHZ3 R-SSC-9023909 https://reactome.org/PathwayBrowser/#/R-SSC-9023909 C3PO hydrolyzes cleaved passenger strand IEA Sus scrofa A0A286ZHZ6 R-SSC-112042 https://reactome.org/PathwayBrowser/#/R-SSC-112042 Opioid binds MOR IEA Sus scrofa A0A286ZHZ6 R-SSC-112271 https://reactome.org/PathwayBrowser/#/R-SSC-112271 The receptor:G-protein complex dissociates IEA Sus scrofa A0A286ZHZ6 R-SSC-167408 https://reactome.org/PathwayBrowser/#/R-SSC-167408 The high affinity receptor complex binds to G-protein IEA Sus scrofa A0A286ZHZ6 R-SSC-167419 https://reactome.org/PathwayBrowser/#/R-SSC-167419 The receptor:G-protein complex releases GDP IEA Sus scrofa A0A286ZHZ6 R-SSC-167427 https://reactome.org/PathwayBrowser/#/R-SSC-167427 Opioid dissociates from MOR IEA Sus scrofa A0A286ZHZ6 R-SSC-167429 https://reactome.org/PathwayBrowser/#/R-SSC-167429 The receptor:G-protein complex binds GTP IEA Sus scrofa A0A286ZHZ6 R-SSC-374298 https://reactome.org/PathwayBrowser/#/R-SSC-374298 Opioid receptors bind opioid peptides IEA Sus scrofa A0A286ZHZ6 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A286ZHZ6 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A286ZHZ6 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A286ZI11 R-SSC-425483 https://reactome.org/PathwayBrowser/#/R-SSC-425483 SLC4A5,7,9 cotransport Na+ with 3HCO3- IEA Sus scrofa A0A286ZI11 R-SSC-9018746 https://reactome.org/PathwayBrowser/#/R-SSC-9018746 RHOQ binds effectors at the plasma membrane IEA Sus scrofa A0A286ZI11 R-SSC-9018758 https://reactome.org/PathwayBrowser/#/R-SSC-9018758 RHOH binds effectors at the plasma membrane IEA Sus scrofa A0A286ZI11 R-SSC-9693125 https://reactome.org/PathwayBrowser/#/R-SSC-9693125 RHOF binds effectors at the plasma membrane IEA Sus scrofa A0A286ZI11 R-SSC-9693198 https://reactome.org/PathwayBrowser/#/R-SSC-9693198 RHOD binds effectors at the plasma membrane IEA Sus scrofa A0A286ZI15 R-SSC-507868 https://reactome.org/PathwayBrowser/#/R-SSC-507868 Aquaporins passively transport water into cells IEA Sus scrofa A0A286ZI15 R-SSC-507870 https://reactome.org/PathwayBrowser/#/R-SSC-507870 Aquaporins passively transport water out of cells IEA Sus scrofa A0A286ZI16 R-SSC-8875320 https://reactome.org/PathwayBrowser/#/R-SSC-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Sus scrofa A0A286ZI16 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A286ZI22 R-SSC-2172666 https://reactome.org/PathwayBrowser/#/R-SSC-2172666 RB1 binds condensin II IEA Sus scrofa A0A286ZI22 R-SSC-2294580 https://reactome.org/PathwayBrowser/#/R-SSC-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Sus scrofa A0A286ZI22 R-SSC-2294590 https://reactome.org/PathwayBrowser/#/R-SSC-2294590 PLK1 binds phosphorylated condensin II complex IEA Sus scrofa A0A286ZI22 R-SSC-2294600 https://reactome.org/PathwayBrowser/#/R-SSC-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Sus scrofa A0A286ZI22 R-SSC-2429719 https://reactome.org/PathwayBrowser/#/R-SSC-2429719 MCPH1 sequesters condensin II IEA Sus scrofa A0A286ZI36 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A286ZI36 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A286ZI36 R-SSC-71670 https://reactome.org/PathwayBrowser/#/R-SSC-71670 PKM dephosphorylates PEP to PYR IEA Sus scrofa A0A286ZI36 R-SSC-9861640 https://reactome.org/PathwayBrowser/#/R-SSC-9861640 CTLH E3 ligase ubiquitinates PKM-1 IEA Sus scrofa A0A286ZI43 R-SSC-6786034 https://reactome.org/PathwayBrowser/#/R-SSC-6786034 CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin IEA Sus scrofa A0A286ZI50 R-SSC-72103 https://reactome.org/PathwayBrowser/#/R-SSC-72103 Formation of pre-mRNPs IEA Sus scrofa A0A286ZI50 R-SSC-9770119 https://reactome.org/PathwayBrowser/#/R-SSC-9770119 Formation of the Spliceosomal E complex IEA Sus scrofa A0A286ZI50 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A286ZI50 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A286ZI50 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A286ZI50 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A286ZI55 R-SSC-75889 https://reactome.org/PathwayBrowser/#/R-SSC-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Sus scrofa A0A286ZI68 R-SSC-6782004 https://reactome.org/PathwayBrowser/#/R-SSC-6782004 Assembly of the pre-incision complex in TC-NER IEA Sus scrofa A0A286ZI68 R-SSC-6782069 https://reactome.org/PathwayBrowser/#/R-SSC-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Sus scrofa A0A286ZI68 R-SSC-6782131 https://reactome.org/PathwayBrowser/#/R-SSC-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa A0A286ZI68 R-SSC-6782138 https://reactome.org/PathwayBrowser/#/R-SSC-6782138 ERCC5 and RPA bind TC-NER site IEA Sus scrofa A0A286ZI68 R-SSC-6782141 https://reactome.org/PathwayBrowser/#/R-SSC-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Sus scrofa A0A286ZI68 R-SSC-6782204 https://reactome.org/PathwayBrowser/#/R-SSC-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Sus scrofa A0A286ZI68 R-SSC-6782208 https://reactome.org/PathwayBrowser/#/R-SSC-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Sus scrofa A0A286ZI68 R-SSC-6782211 https://reactome.org/PathwayBrowser/#/R-SSC-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Sus scrofa A0A286ZI68 R-SSC-6782224 https://reactome.org/PathwayBrowser/#/R-SSC-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Sus scrofa A0A286ZI68 R-SSC-6782227 https://reactome.org/PathwayBrowser/#/R-SSC-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Sus scrofa A0A286ZI68 R-SSC-9684118 https://reactome.org/PathwayBrowser/#/R-SSC-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa A0A286ZI68 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A286ZI68 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A286ZI68 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A286ZI68 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A286ZI77 R-SSC-8867613 https://reactome.org/PathwayBrowser/#/R-SSC-8867613 PICALM binds R-SNAREs IEA Sus scrofa A0A286ZI77 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A286ZI77 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A286ZI77 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A286ZI77 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A286ZI77 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A286ZI77 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A286ZI77 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A286ZI77 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A286ZI77 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A286ZI77 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A286ZI77 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A286ZI77 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A286ZI77 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A286ZI77 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A286ZI80 R-SSC-448963 https://reactome.org/PathwayBrowser/#/R-SSC-448963 Interaction of MyoD:E protein with MEF2 IEA Sus scrofa A0A286ZI91 R-SSC-5357776 https://reactome.org/PathwayBrowser/#/R-SSC-5357776 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG IEA Sus scrofa A0A286ZI91 R-SSC-83582 https://reactome.org/PathwayBrowser/#/R-SSC-83582 TRADD:TRAF2:RIP1 dissociates from TNF-α:TNFR1 IEA Sus scrofa A0A286ZI91 R-SSC-9793680 https://reactome.org/PathwayBrowser/#/R-SSC-9793680 OPTN binds polyUb-RIPK1 within the TNFR1 complex IEA Sus scrofa A0A286ZI91 R-SSC-9796379 https://reactome.org/PathwayBrowser/#/R-SSC-9796379 CYLD:SPATA2:LUBAC binds TNFR1 signaling complex IEA Sus scrofa A0A286ZI91 R-SSC-9817362 https://reactome.org/PathwayBrowser/#/R-SSC-9817362 SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex IEA Sus scrofa A0A286ZI91 R-SSC-9817397 https://reactome.org/PathwayBrowser/#/R-SSC-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Sus scrofa A0A286ZI91 R-SSC-9817400 https://reactome.org/PathwayBrowser/#/R-SSC-9817400 CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex IEA Sus scrofa A0A286ZI91 R-SSC-9817411 https://reactome.org/PathwayBrowser/#/R-SSC-9817411 TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex IEA Sus scrofa A0A286ZI91 R-SSC-9818789 https://reactome.org/PathwayBrowser/#/R-SSC-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 IEA Sus scrofa A0A286ZI91 R-SSC-9818975 https://reactome.org/PathwayBrowser/#/R-SSC-9818975 CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex IEA Sus scrofa A0A286ZI91 R-SSC-9824874 https://reactome.org/PathwayBrowser/#/R-SSC-9824874 OPTN recruits CYLD to the TNFR1 complex IEA Sus scrofa A0A286ZI93 R-SSC-390593 https://reactome.org/PathwayBrowser/#/R-SSC-390593 ATP Hydrolysis By Myosin IEA Sus scrofa A0A286ZI93 R-SSC-390595 https://reactome.org/PathwayBrowser/#/R-SSC-390595 Calcium Binds Troponin-C IEA Sus scrofa A0A286ZI93 R-SSC-390597 https://reactome.org/PathwayBrowser/#/R-SSC-390597 Release Of ADP From Myosin IEA Sus scrofa A0A286ZI93 R-SSC-390598 https://reactome.org/PathwayBrowser/#/R-SSC-390598 Myosin Binds ATP IEA Sus scrofa A0A286ZI97 R-SSC-6789072 https://reactome.org/PathwayBrowser/#/R-SSC-6789072 PGLYRP1 binds bacterial peptidoglycan IEA Sus scrofa A0A286ZI97 R-SSC-6798745 https://reactome.org/PathwayBrowser/#/R-SSC-6798745 Exocytosis of tertiary granule lumen proteins IEA Sus scrofa A0A286ZI97 R-SSC-6798749 https://reactome.org/PathwayBrowser/#/R-SSC-6798749 Exocytosis of specific granule lumen proteins IEA Sus scrofa A0A286ZIA7 R-SSC-164832 https://reactome.org/PathwayBrowser/#/R-SSC-164832 ATPase synthesizes ATP IEA Sus scrofa A0A286ZIA7 R-SSC-164834 https://reactome.org/PathwayBrowser/#/R-SSC-164834 Enzyme-bound ATP is released IEA Sus scrofa A0A286ZIA7 R-SSC-164840 https://reactome.org/PathwayBrowser/#/R-SSC-164840 ADP and Pi bind to ATPase IEA Sus scrofa A0A286ZIA7 R-SSC-8949580 https://reactome.org/PathwayBrowser/#/R-SSC-8949580 F1Fo ATP synthase dimerizes IEA Sus scrofa A0A286ZID2 R-SSC-73632 https://reactome.org/PathwayBrowser/#/R-SSC-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Sus scrofa A0A286ZIE8 R-SSC-1955380 https://reactome.org/PathwayBrowser/#/R-SSC-1955380 TIMM9:TIMM10 transfers proteins to TIMM22 IEA Sus scrofa A0A286ZIE8 R-SSC-5250209 https://reactome.org/PathwayBrowser/#/R-SSC-5250209 ARL2:GTP:ARL2BP binds SLC25A4 IEA Sus scrofa A0A286ZIE8 R-SSC-5672027 https://reactome.org/PathwayBrowser/#/R-SSC-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Sus scrofa A0A286ZIE8 R-SSC-9864415 https://reactome.org/PathwayBrowser/#/R-SSC-9864415 AAC1 imports a proton IEA Sus scrofa A0A286ZIG4 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A286ZIG4 R-SSC-6798749 https://reactome.org/PathwayBrowser/#/R-SSC-6798749 Exocytosis of specific granule lumen proteins IEA Sus scrofa A0A286ZIG4 R-SSC-964958 https://reactome.org/PathwayBrowser/#/R-SSC-964958 2xPDXK:2xZn2+ phosphorylates PXA IEA Sus scrofa A0A286ZIG4 R-SSC-964962 https://reactome.org/PathwayBrowser/#/R-SSC-964962 2xPDKX:2xZn2+ phosphorylates PDX IEA Sus scrofa A0A286ZIG4 R-SSC-964970 https://reactome.org/PathwayBrowser/#/R-SSC-964970 2xPDXK:2xZn2+ phosphorylates PXL IEA Sus scrofa A0A286ZIG9 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A286ZIG9 R-SSC-6809011 https://reactome.org/PathwayBrowser/#/R-SSC-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Sus scrofa A0A286ZIG9 R-SSC-6811433 https://reactome.org/PathwayBrowser/#/R-SSC-6811433 The COG tethering complex interacts with numerous SNAREs at the Golgi membrane IEA Sus scrofa A0A286ZIG9 R-SSC-8849748 https://reactome.org/PathwayBrowser/#/R-SSC-8849748 The COG complex binds RABs at the Golgi membrane IEA Sus scrofa A0A286ZIH1 R-SSC-388824 https://reactome.org/PathwayBrowser/#/R-SSC-388824 PTPRF, PTPRS, PTPRD bind Liprins IEA Sus scrofa A0A286ZIH1 R-SSC-6798257 https://reactome.org/PathwayBrowser/#/R-SSC-6798257 PTPRS binds NTRK3 IEA Sus scrofa A0A286ZIH1 R-SSC-6798258 https://reactome.org/PathwayBrowser/#/R-SSC-6798258 PRTPRF, PTPRS, PTPRD bind LRRC4B IEA Sus scrofa A0A286ZIJ6 R-SSC-378975 https://reactome.org/PathwayBrowser/#/R-SSC-378975 Follitropin is a heterodimer IEA Sus scrofa A0A286ZIJ7 R-SSC-9609921 https://reactome.org/PathwayBrowser/#/R-SSC-9609921 SGTA binds Tail-anchored protein IEA Sus scrofa A0A286ZIL6 R-SSC-9821931 https://reactome.org/PathwayBrowser/#/R-SSC-9821931 BOD1L1 binds SET1A complex IEA Sus scrofa A0A286ZIL9 R-SSC-1592278 https://reactome.org/PathwayBrowser/#/R-SSC-1592278 Autocatalytic activation of proMMP2 IEA Sus scrofa A0A286ZIL9 R-SSC-1604722 https://reactome.org/PathwayBrowser/#/R-SSC-1604722 Activation of proMMP9 by proteases IEA Sus scrofa A0A286ZIL9 R-SSC-1604732 https://reactome.org/PathwayBrowser/#/R-SSC-1604732 Autocatalytic activation of proMMP13 IEA Sus scrofa A0A286ZIL9 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa A0A286ZIL9 R-SSC-1981104 https://reactome.org/PathwayBrowser/#/R-SSC-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Sus scrofa A0A286ZIL9 R-SSC-1981120 https://reactome.org/PathwayBrowser/#/R-SSC-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Sus scrofa A0A286ZIL9 R-SSC-1981128 https://reactome.org/PathwayBrowser/#/R-SSC-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Sus scrofa A0A286ZIL9 R-SSC-1981157 https://reactome.org/PathwayBrowser/#/R-SSC-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Sus scrofa A0A286ZIL9 R-SSC-2002460 https://reactome.org/PathwayBrowser/#/R-SSC-2002460 P4HB binds Collagen chains IEA Sus scrofa A0A286ZIL9 R-SSC-2089971 https://reactome.org/PathwayBrowser/#/R-SSC-2089971 Secretion of collagens IEA Sus scrofa A0A286ZIL9 R-SSC-2168923 https://reactome.org/PathwayBrowser/#/R-SSC-2168923 Collagen type XVIII endostatin release IEA Sus scrofa A0A286ZIL9 R-SSC-2213200 https://reactome.org/PathwayBrowser/#/R-SSC-2213200 Release of endostatin-like peptides IEA Sus scrofa A0A286ZIL9 R-SSC-2471621 https://reactome.org/PathwayBrowser/#/R-SSC-2471621 Endostatin degradation by cathepsins IEA Sus scrofa A0A286ZIL9 R-SSC-4088264 https://reactome.org/PathwayBrowser/#/R-SSC-4088264 Endostatin binds integrin alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 IEA Sus scrofa A0A286ZIL9 R-SSC-8944230 https://reactome.org/PathwayBrowser/#/R-SSC-8944230 Association of procollagen type XVIII IEA Sus scrofa A0A286ZIL9 R-SSC-8948219 https://reactome.org/PathwayBrowser/#/R-SSC-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A286ZIL9 R-SSC-8948222 https://reactome.org/PathwayBrowser/#/R-SSC-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A286ZIL9 R-SSC-8948224 https://reactome.org/PathwayBrowser/#/R-SSC-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A286ZIL9 R-SSC-8948228 https://reactome.org/PathwayBrowser/#/R-SSC-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A286ZIL9 R-SSC-8948231 https://reactome.org/PathwayBrowser/#/R-SSC-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A286ZIL9 R-SSC-8948232 https://reactome.org/PathwayBrowser/#/R-SSC-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Sus scrofa A0A286ZIL9 R-SSC-8948234 https://reactome.org/PathwayBrowser/#/R-SSC-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Sus scrofa A0A286ZIM1 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A286ZIM1 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A286ZIM1 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A286ZIM1 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A286ZIM1 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A286ZIM1 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A286ZIM1 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A286ZIM1 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A286ZIM1 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A286ZIM1 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZIM1 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A286ZIM1 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A286ZIM1 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A286ZIM1 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A286ZIM1 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A286ZIM1 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A286ZIM1 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A286ZIM1 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A286ZIM1 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A286ZIM1 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A286ZIM1 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A286ZIM1 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A286ZIM1 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A286ZIM1 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A286ZIM1 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A286ZIM1 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A286ZIM1 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A286ZIM1 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A286ZIM1 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A286ZIM1 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A286ZIM1 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A286ZIM1 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A286ZIM1 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A286ZIM1 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A286ZIM1 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A286ZIM1 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A286ZIM1 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A286ZIM1 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A286ZIM1 R-SSC-8858498 https://reactome.org/PathwayBrowser/#/R-SSC-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Sus scrofa A0A286ZIM1 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A286ZIM1 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A286ZIM1 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A286ZIM1 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A286ZIM1 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A286ZIM1 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A286ZIM1 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A286ZIM1 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A286ZIM1 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A286ZIM2 R-SSC-199014 https://reactome.org/PathwayBrowser/#/R-SSC-199014 CD96 binds PVR IEA Sus scrofa A0A286ZIN1 R-SSC-8854222 https://reactome.org/PathwayBrowser/#/R-SSC-8854222 TBC1D3 associates with RAB5 IEA Sus scrofa A0A286ZIP0 R-SSC-3000434 https://reactome.org/PathwayBrowser/#/R-SSC-3000434 PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1 IEA Sus scrofa A0A286ZIP0 R-SSC-3215295 https://reactome.org/PathwayBrowser/#/R-SSC-3215295 USP7 deubiquitinates MDM2 IEA Sus scrofa A0A286ZIP0 R-SSC-3222072 https://reactome.org/PathwayBrowser/#/R-SSC-3222072 DAXX binds Ub-MDM2 and USP7 IEA Sus scrofa A0A286ZIP0 R-SSC-416320 https://reactome.org/PathwayBrowser/#/R-SSC-416320 Trafficking of GluR1-containing AMPA receptors IEA Sus scrofa A0A286ZIP0 R-SSC-5228523 https://reactome.org/PathwayBrowser/#/R-SSC-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Sus scrofa A0A286ZIP0 R-SSC-5689950 https://reactome.org/PathwayBrowser/#/R-SSC-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Sus scrofa A0A286ZIP0 R-SSC-6792863 https://reactome.org/PathwayBrowser/#/R-SSC-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Sus scrofa A0A286ZIP0 R-SSC-6792871 https://reactome.org/PathwayBrowser/#/R-SSC-6792871 CCNG1 recruits PP2A-PPP2R5C to MDM2 IEA Sus scrofa A0A286ZIP0 R-SSC-6793661 https://reactome.org/PathwayBrowser/#/R-SSC-6793661 (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 IEA Sus scrofa A0A286ZIP0 R-SSC-6793666 https://reactome.org/PathwayBrowser/#/R-SSC-6793666 MDM2 translocates to the nucleus IEA Sus scrofa A0A286ZIP0 R-SSC-6795460 https://reactome.org/PathwayBrowser/#/R-SSC-6795460 SGK1 phosphorylates MDM2 IEA Sus scrofa A0A286ZIP0 R-SSC-6795667 https://reactome.org/PathwayBrowser/#/R-SSC-6795667 MDM2 translocates to the cytosol IEA Sus scrofa A0A286ZIP0 R-SSC-6798373 https://reactome.org/PathwayBrowser/#/R-SSC-6798373 MDM2 ubiquitinates DYRK2 IEA Sus scrofa A0A286ZIP0 R-SSC-6804253 https://reactome.org/PathwayBrowser/#/R-SSC-6804253 MDM2 ubiquitinates JMY IEA Sus scrofa A0A286ZIP0 R-SSC-6804741 https://reactome.org/PathwayBrowser/#/R-SSC-6804741 MDM2 forms homo- or heterodimers IEA Sus scrofa A0A286ZIP0 R-SSC-6804942 https://reactome.org/PathwayBrowser/#/R-SSC-6804942 MDM2 homodimers auto-ubiquitinate IEA Sus scrofa A0A286ZIP0 R-SSC-6804955 https://reactome.org/PathwayBrowser/#/R-SSC-6804955 ATM phosphorylates MDM2 IEA Sus scrofa A0A286ZIP0 R-SSC-8952371 https://reactome.org/PathwayBrowser/#/R-SSC-8952371 MDM2 binds RUNX3 IEA Sus scrofa A0A286ZIP0 R-SSC-8952382 https://reactome.org/PathwayBrowser/#/R-SSC-8952382 MDM2 polyubiquitinates RUNX3 IEA Sus scrofa A0A286ZIP1 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A286ZIP1 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A286ZIP1 R-SSC-8875320 https://reactome.org/PathwayBrowser/#/R-SSC-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Sus scrofa A0A286ZIP1 R-SSC-8877311 https://reactome.org/PathwayBrowser/#/R-SSC-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 IEA Sus scrofa A0A286ZIP2 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A286ZIP2 R-SSC-444731 https://reactome.org/PathwayBrowser/#/R-SSC-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Sus scrofa A0A286ZIP2 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A286ZIP2 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A286ZIQ2 R-SSC-8936519 https://reactome.org/PathwayBrowser/#/R-SSC-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Sus scrofa A0A286ZIR2 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A286ZIR2 R-SSC-5672083 https://reactome.org/PathwayBrowser/#/R-SSC-5672083 KTN1 binds Kinesin-1 IEA Sus scrofa A0A286ZIR2 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa A0A286ZIR2 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa A0A286ZIR2 R-SSC-983194 https://reactome.org/PathwayBrowser/#/R-SSC-983194 Kinesin-1 is a heterotetramer IEA Sus scrofa A0A286ZIR2 R-SSC-983259 https://reactome.org/PathwayBrowser/#/R-SSC-983259 Kinesins move along microtubules consuming ATP IEA Sus scrofa A0A286ZIR2 R-SSC-983266 https://reactome.org/PathwayBrowser/#/R-SSC-983266 Kinesins bind microtubules IEA Sus scrofa A0A286ZIR9 R-SSC-508561 https://reactome.org/PathwayBrowser/#/R-SSC-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate IEA Sus scrofa A0A286ZIR9 R-SSC-70952 https://reactome.org/PathwayBrowser/#/R-SSC-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate IEA Sus scrofa A0A286ZIR9 R-SSC-893583 https://reactome.org/PathwayBrowser/#/R-SSC-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate IEA Sus scrofa A0A286ZIT4 R-SSC-909718 https://reactome.org/PathwayBrowser/#/R-SSC-909718 Formation of p-STAT1 homodimer IEA Sus scrofa A0A286ZIT4 R-SSC-909719 https://reactome.org/PathwayBrowser/#/R-SSC-909719 Recruitment of STAT2 to p-IFNAR1 IEA Sus scrofa A0A286ZIT4 R-SSC-909720 https://reactome.org/PathwayBrowser/#/R-SSC-909720 IFN alpha/beta binds to IFNAR2 IEA Sus scrofa A0A286ZIT4 R-SSC-909722 https://reactome.org/PathwayBrowser/#/R-SSC-909722 Release of p-STAT2:p-STAT1 dimer IEA Sus scrofa A0A286ZIT4 R-SSC-909724 https://reactome.org/PathwayBrowser/#/R-SSC-909724 Recruitment of IFNAR1 IEA Sus scrofa A0A286ZIT4 R-SSC-909729 https://reactome.org/PathwayBrowser/#/R-SSC-909729 Activation of JAK kinases IEA Sus scrofa A0A286ZIT4 R-SSC-909730 https://reactome.org/PathwayBrowser/#/R-SSC-909730 Phosphorylation of INFAR1 by TYK2 IEA Sus scrofa A0A286ZIT4 R-SSC-909732 https://reactome.org/PathwayBrowser/#/R-SSC-909732 Phosphorylation of STAT2 IEA Sus scrofa A0A286ZIT4 R-SSC-912685 https://reactome.org/PathwayBrowser/#/R-SSC-912685 UBP43 binds IFNAR2 and prevents JAK1 interaction IEA Sus scrofa A0A286ZIT4 R-SSC-9678935 https://reactome.org/PathwayBrowser/#/R-SSC-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Sus scrofa A0A286ZIT4 R-SSC-9696179 https://reactome.org/PathwayBrowser/#/R-SSC-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Sus scrofa A0A286ZIT4 R-SSC-997309 https://reactome.org/PathwayBrowser/#/R-SSC-997309 Dephosphorylation of STAT1 by SHP2 IEA Sus scrofa A0A286ZIT4 R-SSC-997311 https://reactome.org/PathwayBrowser/#/R-SSC-997311 Dephosphorylation of TYK2 by PTP1B IEA Sus scrofa A0A286ZIT4 R-SSC-997314 https://reactome.org/PathwayBrowser/#/R-SSC-997314 Dephosphorylation of JAK1 by SHP1 IEA Sus scrofa A0A286ZIU3 R-SSC-428127 https://reactome.org/PathwayBrowser/#/R-SSC-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Sus scrofa A0A286ZIU3 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A286ZIU3 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A286ZIV1 R-SSC-8850529 https://reactome.org/PathwayBrowser/#/R-SSC-8850529 RGS proteins bind GNB5 and CCT/TRiC IEA Sus scrofa A0A286ZIV1 R-SSC-8850539 https://reactome.org/PathwayBrowser/#/R-SSC-8850539 Release of GNB5:RGS dimers from CCT/TRiC IEA Sus scrofa A0A286ZIV1 R-SSC-8982012 https://reactome.org/PathwayBrowser/#/R-SSC-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Sus scrofa A0A286ZIV1 R-SSC-8982019 https://reactome.org/PathwayBrowser/#/R-SSC-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Sus scrofa A0A286ZIV1 R-SSC-8982020 https://reactome.org/PathwayBrowser/#/R-SSC-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Sus scrofa A0A286ZIV2 R-SSC-8854759 https://reactome.org/PathwayBrowser/#/R-SSC-8854759 TBC1D14 binds RAB11 and ULK1 IEA Sus scrofa A0A286ZIV3 R-SSC-5686924 https://reactome.org/PathwayBrowser/#/R-SSC-5686924 DCLRE1C binds PRKDC:XRCC5:XRCC6 at DNA DSBs IEA Sus scrofa A0A286ZIV3 R-SSC-5687183 https://reactome.org/PathwayBrowser/#/R-SSC-5687183 PRKDC phosphorylates DCLRE1C at DNA DSBs IEA Sus scrofa A0A286ZIV3 R-SSC-5687360 https://reactome.org/PathwayBrowser/#/R-SSC-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Sus scrofa A0A286ZIV3 R-SSC-5693533 https://reactome.org/PathwayBrowser/#/R-SSC-5693533 DCLRE1C (ARTEMIS) processes DNA DSB ends IEA Sus scrofa A0A286ZIV3 R-SSC-5693575 https://reactome.org/PathwayBrowser/#/R-SSC-5693575 DNA-PKcs autophosphorylates IEA Sus scrofa A0A286ZIV3 R-SSC-5693578 https://reactome.org/PathwayBrowser/#/R-SSC-5693578 TDP1 and TDP2 process unligatable DSB ends IEA Sus scrofa A0A286ZIV3 R-SSC-5693615 https://reactome.org/PathwayBrowser/#/R-SSC-5693615 Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis IEA Sus scrofa A0A286ZIV3 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A286ZIZ7 R-SSC-3299753 https://reactome.org/PathwayBrowser/#/R-SSC-3299753 CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 IEA Sus scrofa A0A286ZIZ7 R-SSC-3697860 https://reactome.org/PathwayBrowser/#/R-SSC-3697860 SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ IEA Sus scrofa A0A286ZIZ7 R-SSC-8951723 https://reactome.org/PathwayBrowser/#/R-SSC-8951723 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates IEA Sus scrofa A0A286ZJ05 R-SSC-6807875 https://reactome.org/PathwayBrowser/#/R-SSC-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Sus scrofa A0A286ZJ05 R-SSC-6807877 https://reactome.org/PathwayBrowser/#/R-SSC-6807877 ARFGAPs stimulate ARF GTPase activity IEA Sus scrofa A0A286ZJ05 R-SSC-6811417 https://reactome.org/PathwayBrowser/#/R-SSC-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Sus scrofa A0A286ZJ05 R-SSC-6811418 https://reactome.org/PathwayBrowser/#/R-SSC-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Sus scrofa A0A286ZJ05 R-SSC-8856808 https://reactome.org/PathwayBrowser/#/R-SSC-8856808 Recruitment of AP-2 complex and clathrin IEA Sus scrofa A0A286ZJ06 R-SSC-1482679 https://reactome.org/PathwayBrowser/#/R-SSC-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Sus scrofa A0A286ZJ06 R-SSC-1482776 https://reactome.org/PathwayBrowser/#/R-SSC-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Sus scrofa A0A286ZJ06 R-SSC-1482816 https://reactome.org/PathwayBrowser/#/R-SSC-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Sus scrofa A0A286ZJ06 R-SSC-1482868 https://reactome.org/PathwayBrowser/#/R-SSC-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Sus scrofa A0A286ZJ06 R-SSC-1482887 https://reactome.org/PathwayBrowser/#/R-SSC-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Sus scrofa A0A286ZJ06 R-SSC-1482907 https://reactome.org/PathwayBrowser/#/R-SSC-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Sus scrofa A0A286ZJ06 R-SSC-1602368 https://reactome.org/PathwayBrowser/#/R-SSC-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Sus scrofa A0A286ZJ06 R-SSC-1602374 https://reactome.org/PathwayBrowser/#/R-SSC-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Sus scrofa A0A286ZJ06 R-SSC-1602377 https://reactome.org/PathwayBrowser/#/R-SSC-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Sus scrofa A0A286ZJ06 R-SSC-1602398 https://reactome.org/PathwayBrowser/#/R-SSC-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Sus scrofa A0A286ZJ06 R-SSC-1602417 https://reactome.org/PathwayBrowser/#/R-SSC-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Sus scrofa A0A286ZJ06 R-SSC-1602446 https://reactome.org/PathwayBrowser/#/R-SSC-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Sus scrofa A0A286ZJ06 R-SSC-8862771 https://reactome.org/PathwayBrowser/#/R-SSC-8862771 PLA2G2A binds bacterial phospholipids IEA Sus scrofa A0A286ZJ09 R-SSC-392054 https://reactome.org/PathwayBrowser/#/R-SSC-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Sus scrofa A0A286ZJ09 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A286ZJ09 R-SSC-6807875 https://reactome.org/PathwayBrowser/#/R-SSC-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Sus scrofa A0A286ZJ09 R-SSC-6807877 https://reactome.org/PathwayBrowser/#/R-SSC-6807877 ARFGAPs stimulate ARF GTPase activity IEA Sus scrofa A0A286ZJ09 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa A0A286ZJ09 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A286ZJ09 R-SSC-6809011 https://reactome.org/PathwayBrowser/#/R-SSC-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Sus scrofa A0A286ZJ20 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A286ZJ25 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A286ZJ25 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A286ZJ25 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A286ZJ25 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A286ZJ25 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A286ZJ52 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A286ZJ52 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A286ZJ52 R-SSC-141423 https://reactome.org/PathwayBrowser/#/R-SSC-141423 Binding of the MCC complex to the APC/C complex IEA Sus scrofa A0A286ZJ52 R-SSC-141429 https://reactome.org/PathwayBrowser/#/R-SSC-141429 Inactivation of APC/C via CDC20 sequestration IEA Sus scrofa A0A286ZJ52 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A286ZJ52 R-SSC-141437 https://reactome.org/PathwayBrowser/#/R-SSC-141437 Formation of the MCC complex IEA Sus scrofa A0A286ZJ52 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A286ZJ52 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A286ZJ52 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A286ZJ52 R-SSC-174104 https://reactome.org/PathwayBrowser/#/R-SSC-174104 Ubiquitination of Cyclin A by APC/C:Cdc20 complex IEA Sus scrofa A0A286ZJ52 R-SSC-174171 https://reactome.org/PathwayBrowser/#/R-SSC-174171 Association of Cyclin A with the APC/C IEA Sus scrofa A0A286ZJ52 R-SSC-174238 https://reactome.org/PathwayBrowser/#/R-SSC-174238 Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 IEA Sus scrofa A0A286ZJ52 R-SSC-174255 https://reactome.org/PathwayBrowser/#/R-SSC-174255 Degradation multiubiquitinated Cyclin A IEA Sus scrofa A0A286ZJ52 R-SSC-179417 https://reactome.org/PathwayBrowser/#/R-SSC-179417 Multiubiquitination of Nek2A IEA Sus scrofa A0A286ZJ52 R-SSC-179421 https://reactome.org/PathwayBrowser/#/R-SSC-179421 Degradation of multiubiquitinated Nek2A IEA Sus scrofa A0A286ZJ52 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A286ZJ52 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A286ZJ52 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A286ZJ52 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A286ZJ52 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A286ZJ52 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A286ZJ52 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A286ZJ52 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A286ZJ52 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A286ZJ74 R-SSC-111439 https://reactome.org/PathwayBrowser/#/R-SSC-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Sus scrofa A0A286ZJ74 R-SSC-158441 https://reactome.org/PathwayBrowser/#/R-SSC-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Sus scrofa A0A286ZJ74 R-SSC-158447 https://reactome.org/PathwayBrowser/#/R-SSC-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Sus scrofa A0A286ZJ74 R-SSC-158481 https://reactome.org/PathwayBrowser/#/R-SSC-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Sus scrofa A0A286ZJ74 R-SSC-158484 https://reactome.org/PathwayBrowser/#/R-SSC-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Sus scrofa A0A286ZJ74 R-SSC-159046 https://reactome.org/PathwayBrowser/#/R-SSC-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Sus scrofa A0A286ZJ74 R-SSC-159050 https://reactome.org/PathwayBrowser/#/R-SSC-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Sus scrofa A0A286ZJ74 R-SSC-191830 https://reactome.org/PathwayBrowser/#/R-SSC-191830 snRNP nuclear import and release IEA Sus scrofa A0A286ZJ74 R-SSC-2990880 https://reactome.org/PathwayBrowser/#/R-SSC-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Sus scrofa A0A286ZJ74 R-SSC-2990882 https://reactome.org/PathwayBrowser/#/R-SSC-2990882 CDK1 phosphorylates NUP98 IEA Sus scrofa A0A286ZJ74 R-SSC-3000348 https://reactome.org/PathwayBrowser/#/R-SSC-3000348 RANBP2 SUMOylates SP100 with SUMO2 IEA Sus scrofa A0A286ZJ74 R-SSC-3000399 https://reactome.org/PathwayBrowser/#/R-SSC-3000399 RANBP2 SUMOylates SP100 with SUMO1 IEA Sus scrofa A0A286ZJ74 R-SSC-3000411 https://reactome.org/PathwayBrowser/#/R-SSC-3000411 RANBP2 SUMOylates PML with SUMO2 IEA Sus scrofa A0A286ZJ74 R-SSC-4551649 https://reactome.org/PathwayBrowser/#/R-SSC-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Sus scrofa A0A286ZJ74 R-SSC-4551679 https://reactome.org/PathwayBrowser/#/R-SSC-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Sus scrofa A0A286ZJ74 R-SSC-4570493 https://reactome.org/PathwayBrowser/#/R-SSC-4570493 RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 IEA Sus scrofa A0A286ZJ74 R-SSC-4615872 https://reactome.org/PathwayBrowser/#/R-SSC-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Sus scrofa A0A286ZJ74 R-SSC-4615987 https://reactome.org/PathwayBrowser/#/R-SSC-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Sus scrofa A0A286ZJ74 R-SSC-4655355 https://reactome.org/PathwayBrowser/#/R-SSC-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Sus scrofa A0A286ZJ74 R-SSC-5228508 https://reactome.org/PathwayBrowser/#/R-SSC-5228508 RANBP2 SUMOylates PML with SUMO1 IEA Sus scrofa A0A286ZJ74 R-SSC-5228523 https://reactome.org/PathwayBrowser/#/R-SSC-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Sus scrofa A0A286ZJ74 R-SSC-5252041 https://reactome.org/PathwayBrowser/#/R-SSC-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Sus scrofa A0A286ZJ74 R-SSC-5578744 https://reactome.org/PathwayBrowser/#/R-SSC-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Sus scrofa A0A286ZJ74 R-SSC-75097 https://reactome.org/PathwayBrowser/#/R-SSC-75097 Transport of the export-competent mRNP complex through the NPC IEA Sus scrofa A0A286ZJ74 R-SSC-75098 https://reactome.org/PathwayBrowser/#/R-SSC-75098 mRNP complex dissociates from cytosolic face of NPC IEA Sus scrofa A0A286ZJ74 R-SSC-77587 https://reactome.org/PathwayBrowser/#/R-SSC-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Sus scrofa A0A286ZJ74 R-SSC-77594 https://reactome.org/PathwayBrowser/#/R-SSC-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Sus scrofa A0A286ZJ75 R-SSC-201629 https://reactome.org/PathwayBrowser/#/R-SSC-201629 Caspase-mediated cleavage of Tau IEA Sus scrofa A0A286ZJ75 R-SSC-9836404 https://reactome.org/PathwayBrowser/#/R-SSC-9836404 p-PKR dimer phosphorylates MAPT IEA Sus scrofa A0A286ZJ81 R-SSC-1296127 https://reactome.org/PathwayBrowser/#/R-SSC-1296127 Activation of voltage gated Potassium channels IEA Sus scrofa A0A286ZJA8 R-SSC-72670 https://reactome.org/PathwayBrowser/#/R-SSC-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Sus scrofa A0A286ZJA8 R-SSC-72722 https://reactome.org/PathwayBrowser/#/R-SSC-72722 eIF2 activation IEA Sus scrofa A0A286ZJB7 R-SSC-210420 https://reactome.org/PathwayBrowser/#/R-SSC-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Sus scrofa A0A286ZJB7 R-SSC-416320 https://reactome.org/PathwayBrowser/#/R-SSC-416320 Trafficking of GluR1-containing AMPA receptors IEA Sus scrofa A0A286ZJB7 R-SSC-5577213 https://reactome.org/PathwayBrowser/#/R-SSC-5577213 LTCC multimer transports Ca2+ from extracellular region to cytosol IEA Sus scrofa A0A286ZJB7 R-SSC-5682794 https://reactome.org/PathwayBrowser/#/R-SSC-5682794 LGI1 binds ADAM22 and ADAM23 IEA Sus scrofa A0A286ZJB7 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa A0A286ZJC9 R-SSC-445699 https://reactome.org/PathwayBrowser/#/R-SSC-445699 ATP Hydrolysis By Myosin IEA Sus scrofa A0A286ZJC9 R-SSC-445700 https://reactome.org/PathwayBrowser/#/R-SSC-445700 Myosin Binds ATP IEA Sus scrofa A0A286ZJC9 R-SSC-445704 https://reactome.org/PathwayBrowser/#/R-SSC-445704 Calcium Binds Caldesmon IEA Sus scrofa A0A286ZJC9 R-SSC-445705 https://reactome.org/PathwayBrowser/#/R-SSC-445705 Release Of ADP From Myosin IEA Sus scrofa A0A286ZJD1 R-SSC-8952638 https://reactome.org/PathwayBrowser/#/R-SSC-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZJD1 R-SSC-8955245 https://reactome.org/PathwayBrowser/#/R-SSC-8955245 CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus IEA Sus scrofa A0A286ZJD1 R-SSC-8955285 https://reactome.org/PathwayBrowser/#/R-SSC-8955285 COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZJD1 R-SSC-8956045 https://reactome.org/PathwayBrowser/#/R-SSC-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZJD8 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A286ZJE7 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A286ZJF0 R-SSC-265422 https://reactome.org/PathwayBrowser/#/R-SSC-265422 Interaction of integrin alphaEbeta7 with Cadherin-1 IEA Sus scrofa A0A286ZJF6 R-SSC-8857549 https://reactome.org/PathwayBrowser/#/R-SSC-8857549 HBEGF-bound EGFR forms a heterodimer with GPNMB IEA Sus scrofa A0A286ZJF6 R-SSC-8857555 https://reactome.org/PathwayBrowser/#/R-SSC-8857555 EGFR phosphorylates GPNMB IEA Sus scrofa A0A286ZJF6 R-SSC-8857577 https://reactome.org/PathwayBrowser/#/R-SSC-8857577 LINC01139 facilitates PTK6 autophosphorylation IEA Sus scrofa A0A286ZJF6 R-SSC-8857583 https://reactome.org/PathwayBrowser/#/R-SSC-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Sus scrofa A0A286ZJF6 R-SSC-9634702 https://reactome.org/PathwayBrowser/#/R-SSC-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Sus scrofa A0A286ZJH5 R-SSC-8874204 https://reactome.org/PathwayBrowser/#/R-SSC-8874204 MBTPS1 (S1P) cleaves CREB3 IEA Sus scrofa A0A286ZJH5 R-SSC-8874849 https://reactome.org/PathwayBrowser/#/R-SSC-8874849 CREBRF binds CREB3 IEA Sus scrofa A0A286ZJI5 R-SSC-1011598 https://reactome.org/PathwayBrowser/#/R-SSC-1011598 DOCKs bind to RhoGEFs IEA Sus scrofa A0A286ZJI5 R-SSC-8875576 https://reactome.org/PathwayBrowser/#/R-SSC-8875576 CRK,CRKL recruits RAC1 GEF to activated MET IEA Sus scrofa A0A286ZJI5 R-SSC-8875591 https://reactome.org/PathwayBrowser/#/R-SSC-8875591 DOCK7 activates RAC1 IEA Sus scrofa A0A286ZJI5 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A286ZJI5 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa A0A286ZJJ6 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A286ZJJ6 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A286ZJJ6 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A286ZJJ6 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A286ZJJ6 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A286ZJL9 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A286ZJL9 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A286ZJL9 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A286ZJL9 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A286ZJL9 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A286ZJL9 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A286ZJL9 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A286ZJL9 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZJL9 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A286ZJL9 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A286ZJL9 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A286ZJL9 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A286ZJL9 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A286ZJL9 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A286ZJL9 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A286ZJL9 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A286ZJL9 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A286ZJL9 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A286ZJL9 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A286ZJL9 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A286ZJL9 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A286ZJL9 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A286ZJL9 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A286ZJM1 R-SSC-1236398 https://reactome.org/PathwayBrowser/#/R-SSC-1236398 ERBB4 binds NRGs or EGF-like ligands IEA Sus scrofa A0A286ZJM1 R-SSC-1250195 https://reactome.org/PathwayBrowser/#/R-SSC-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Sus scrofa A0A286ZJM1 R-SSC-1250220 https://reactome.org/PathwayBrowser/#/R-SSC-1250220 Homodimerization of ERBB4 IEA Sus scrofa A0A286ZJM1 R-SSC-1250315 https://reactome.org/PathwayBrowser/#/R-SSC-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Sus scrofa A0A286ZJM1 R-SSC-1250346 https://reactome.org/PathwayBrowser/#/R-SSC-1250346 Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers IEA Sus scrofa A0A286ZJM1 R-SSC-1250348 https://reactome.org/PathwayBrowser/#/R-SSC-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Sus scrofa A0A286ZJM1 R-SSC-1250353 https://reactome.org/PathwayBrowser/#/R-SSC-1250353 Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers IEA Sus scrofa A0A286ZJM1 R-SSC-1250357 https://reactome.org/PathwayBrowser/#/R-SSC-1250357 SHC1 binds P-ERBB4 isoform dimers IEA Sus scrofa A0A286ZJM1 R-SSC-1250370 https://reactome.org/PathwayBrowser/#/R-SSC-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Sus scrofa A0A286ZJM1 R-SSC-1250380 https://reactome.org/PathwayBrowser/#/R-SSC-1250380 Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers IEA Sus scrofa A0A286ZJM1 R-SSC-1250383 https://reactome.org/PathwayBrowser/#/R-SSC-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Sus scrofa A0A286ZJM1 R-SSC-1306969 https://reactome.org/PathwayBrowser/#/R-SSC-1306969 GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers IEA Sus scrofa A0A286ZJM1 R-SSC-1306972 https://reactome.org/PathwayBrowser/#/R-SSC-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Sus scrofa A0A286ZJM1 R-SSC-1306979 https://reactome.org/PathwayBrowser/#/R-SSC-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Sus scrofa A0A286ZJM1 R-SSC-1963563 https://reactome.org/PathwayBrowser/#/R-SSC-1963563 MATK (CSK homologous kinase) binds phosphorylated ERBB2 IEA Sus scrofa A0A286ZJM1 R-SSC-1963581 https://reactome.org/PathwayBrowser/#/R-SSC-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Sus scrofa A0A286ZJM1 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa A0A286ZJM1 R-SSC-1963586 https://reactome.org/PathwayBrowser/#/R-SSC-1963586 SRC family kinases phosphorylate ERBB2 IEA Sus scrofa A0A286ZJM1 R-SSC-1977958 https://reactome.org/PathwayBrowser/#/R-SSC-1977958 ERBB4 forms heterodimers with ERBB3 IEA Sus scrofa A0A286ZJM1 R-SSC-1977959 https://reactome.org/PathwayBrowser/#/R-SSC-1977959 ERBB4 forms heterodimers with EGFR IEA Sus scrofa A0A286ZJM1 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZJM1 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A286ZJM1 R-SSC-6785636 https://reactome.org/PathwayBrowser/#/R-SSC-6785636 Phosphorylated ERBB2 heterodimers bind MEMO1 IEA Sus scrofa A0A286ZJM1 R-SSC-6785648 https://reactome.org/PathwayBrowser/#/R-SSC-6785648 MEMO1 binds RHOA:GTP:DIAPH1 IEA Sus scrofa A0A286ZJM1 R-SSC-8847995 https://reactome.org/PathwayBrowser/#/R-SSC-8847995 Activated ERBB2 binds PTK6 (BRK) IEA Sus scrofa A0A286ZJM1 R-SSC-8848005 https://reactome.org/PathwayBrowser/#/R-SSC-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Sus scrofa A0A286ZJM1 R-SSC-8863804 https://reactome.org/PathwayBrowser/#/R-SSC-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Sus scrofa A0A286ZJM4 R-SSC-176298 https://reactome.org/PathwayBrowser/#/R-SSC-176298 Activation of claspin IEA Sus scrofa A0A286ZJM4 R-SSC-176318 https://reactome.org/PathwayBrowser/#/R-SSC-176318 Loading of claspin onto DNA during replication origin firing IEA Sus scrofa A0A286ZJM4 R-SSC-68914 https://reactome.org/PathwayBrowser/#/R-SSC-68914 DNA polymerase alpha:primase binds at the origin IEA Sus scrofa A0A286ZJM4 R-SSC-68916 https://reactome.org/PathwayBrowser/#/R-SSC-68916 DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin IEA Sus scrofa A0A286ZJM4 R-SSC-68917 https://reactome.org/PathwayBrowser/#/R-SSC-68917 Cdc45 associates with the pre-replicative complex at the origin IEA Sus scrofa A0A286ZJM4 R-SSC-68918 https://reactome.org/PathwayBrowser/#/R-SSC-68918 CDK and DDK associate with the Mcm10:pre-replicative complex IEA Sus scrofa A0A286ZJM4 R-SSC-68919 https://reactome.org/PathwayBrowser/#/R-SSC-68919 Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 IEA Sus scrofa A0A286ZJM4 R-SSC-68940 https://reactome.org/PathwayBrowser/#/R-SSC-68940 Cdt1 is displaced from the pre-replicative complex IEA Sus scrofa A0A286ZJM4 R-SSC-68944 https://reactome.org/PathwayBrowser/#/R-SSC-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Sus scrofa A0A286ZJM4 R-SSC-68954 https://reactome.org/PathwayBrowser/#/R-SSC-68954 Mcm2-7 is phosphorylated by DDK IEA Sus scrofa A0A286ZJM4 R-SSC-68960 https://reactome.org/PathwayBrowser/#/R-SSC-68960 DNA polymerase epsilon binds at the origin IEA Sus scrofa A0A286ZJM4 R-SSC-69019 https://reactome.org/PathwayBrowser/#/R-SSC-69019 Mcm4,6,7 trimer forms and associates with the replication fork IEA Sus scrofa A0A286ZJM4 R-SSC-9749253 https://reactome.org/PathwayBrowser/#/R-SSC-9749253 Formation of MCM2-7 complex IEA Sus scrofa A0A286ZJM4 R-SSC-9757257 https://reactome.org/PathwayBrowser/#/R-SSC-9757257 MCM4, MCM6 and MCM7 form a heterotrimer IEA Sus scrofa A0A286ZJM4 R-SSC-9757258 https://reactome.org/PathwayBrowser/#/R-SSC-9757258 MCM2 binds MCM4:MCM6:MCM7 heterotrimer IEA Sus scrofa A0A286ZJN6 R-SSC-5675373 https://reactome.org/PathwayBrowser/#/R-SSC-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Sus scrofa A0A286ZJN6 R-SSC-5675376 https://reactome.org/PathwayBrowser/#/R-SSC-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Sus scrofa A0A286ZJN9 R-SSC-8848246 https://reactome.org/PathwayBrowser/#/R-SSC-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA IEA Sus scrofa A0A286ZJP1 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJP1 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJP1 R-SSC-9018758 https://reactome.org/PathwayBrowser/#/R-SSC-9018758 RHOH binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJP1 R-SSC-9018794 https://reactome.org/PathwayBrowser/#/R-SSC-9018794 RHOV binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJP1 R-SSC-9693198 https://reactome.org/PathwayBrowser/#/R-SSC-9693198 RHOD binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJQ0 R-SSC-212222 https://reactome.org/PathwayBrowser/#/R-SSC-212222 PRC2 recruits DNA methyltransferases IEA Sus scrofa A0A286ZJQ0 R-SSC-212252 https://reactome.org/PathwayBrowser/#/R-SSC-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Sus scrofa A0A286ZJQ0 R-SSC-212263 https://reactome.org/PathwayBrowser/#/R-SSC-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Sus scrofa A0A286ZJQ0 R-SSC-212269 https://reactome.org/PathwayBrowser/#/R-SSC-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-3214912 https://reactome.org/PathwayBrowser/#/R-SSC-3214912 KDM1A, KDM1B demethylate MeK5-histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-3222593 https://reactome.org/PathwayBrowser/#/R-SSC-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-3229089 https://reactome.org/PathwayBrowser/#/R-SSC-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-3229102 https://reactome.org/PathwayBrowser/#/R-SSC-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Sus scrofa A0A286ZJQ0 R-SSC-3240295 https://reactome.org/PathwayBrowser/#/R-SSC-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-3247569 https://reactome.org/PathwayBrowser/#/R-SSC-3247569 PADI4 deiminates Histones IEA Sus scrofa A0A286ZJQ0 R-SSC-3318486 https://reactome.org/PathwayBrowser/#/R-SSC-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-3662335 https://reactome.org/PathwayBrowser/#/R-SSC-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Sus scrofa A0A286ZJQ0 R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa A0A286ZJQ0 R-SSC-3777129 https://reactome.org/PathwayBrowser/#/R-SSC-3777129 HDAC3 containing complexes deacetylate histone IEA Sus scrofa A0A286ZJQ0 R-SSC-3782637 https://reactome.org/PathwayBrowser/#/R-SSC-3782637 HDAC8 deacetylates histones IEA Sus scrofa A0A286ZJQ0 R-SSC-3782655 https://reactome.org/PathwayBrowser/#/R-SSC-3782655 HDAC10 deacetylates histone IEA Sus scrofa A0A286ZJQ0 R-SSC-3788745 https://reactome.org/PathwayBrowser/#/R-SSC-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-3788748 https://reactome.org/PathwayBrowser/#/R-SSC-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-427337 https://reactome.org/PathwayBrowser/#/R-SSC-427337 MBD2 binds methylcytosine in chromatin IEA Sus scrofa A0A286ZJQ0 R-SSC-427514 https://reactome.org/PathwayBrowser/#/R-SSC-427514 eNoSC deacetylates histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-427527 https://reactome.org/PathwayBrowser/#/R-SSC-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Sus scrofa A0A286ZJQ0 R-SSC-427528 https://reactome.org/PathwayBrowser/#/R-SSC-427528 Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) IEA Sus scrofa A0A286ZJQ0 R-SSC-4722133 https://reactome.org/PathwayBrowser/#/R-SSC-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-4724279 https://reactome.org/PathwayBrowser/#/R-SSC-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-4724284 https://reactome.org/PathwayBrowser/#/R-SSC-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-4754176 https://reactome.org/PathwayBrowser/#/R-SSC-4754176 JMJD6 demethylates MeR3-histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-4754181 https://reactome.org/PathwayBrowser/#/R-SSC-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-4754187 https://reactome.org/PathwayBrowser/#/R-SSC-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-4827382 https://reactome.org/PathwayBrowser/#/R-SSC-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Sus scrofa A0A286ZJQ0 R-SSC-4827383 https://reactome.org/PathwayBrowser/#/R-SSC-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Sus scrofa A0A286ZJQ0 R-SSC-5159245 https://reactome.org/PathwayBrowser/#/R-SSC-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Sus scrofa A0A286ZJQ0 R-SSC-5205799 https://reactome.org/PathwayBrowser/#/R-SSC-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Sus scrofa A0A286ZJQ0 R-SSC-5205822 https://reactome.org/PathwayBrowser/#/R-SSC-5205822 CARM1 methylates arginine-18 (H3R17) of histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-5205824 https://reactome.org/PathwayBrowser/#/R-SSC-5205824 CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) IEA Sus scrofa A0A286ZJQ0 R-SSC-5218952 https://reactome.org/PathwayBrowser/#/R-SSC-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Sus scrofa A0A286ZJQ0 R-SSC-5225602 https://reactome.org/PathwayBrowser/#/R-SSC-5225602 WDR5 binds Me2sR3-replicative histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-5225649 https://reactome.org/PathwayBrowser/#/R-SSC-5225649 RBBP7 binds histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-5229010 https://reactome.org/PathwayBrowser/#/R-SSC-5229010 CARM1 methylates arginine-27 of histone H3 (H3R26) IEA Sus scrofa A0A286ZJQ0 R-SSC-5244692 https://reactome.org/PathwayBrowser/#/R-SSC-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Sus scrofa A0A286ZJQ0 R-SSC-5250938 https://reactome.org/PathwayBrowser/#/R-SSC-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Sus scrofa A0A286ZJQ0 R-SSC-5578742 https://reactome.org/PathwayBrowser/#/R-SSC-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Sus scrofa A0A286ZJQ0 R-SSC-5625774 https://reactome.org/PathwayBrowser/#/R-SSC-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Sus scrofa A0A286ZJQ0 R-SSC-5625784 https://reactome.org/PathwayBrowser/#/R-SSC-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Sus scrofa A0A286ZJQ0 R-SSC-5625796 https://reactome.org/PathwayBrowser/#/R-SSC-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Sus scrofa A0A286ZJQ0 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa A0A286ZJQ0 R-SSC-5625848 https://reactome.org/PathwayBrowser/#/R-SSC-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa A0A286ZJQ0 R-SSC-5625849 https://reactome.org/PathwayBrowser/#/R-SSC-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Sus scrofa A0A286ZJQ0 R-SSC-5625870 https://reactome.org/PathwayBrowser/#/R-SSC-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa A0A286ZJQ0 R-SSC-5634729 https://reactome.org/PathwayBrowser/#/R-SSC-5634729 EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) IEA Sus scrofa A0A286ZJQ0 R-SSC-5634750 https://reactome.org/PathwayBrowser/#/R-SSC-5634750 EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) IEA Sus scrofa A0A286ZJQ0 R-SSC-5634802 https://reactome.org/PathwayBrowser/#/R-SSC-5634802 MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) IEA Sus scrofa A0A286ZJQ0 R-SSC-5637686 https://reactome.org/PathwayBrowser/#/R-SSC-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Sus scrofa A0A286ZJQ0 R-SSC-5638141 https://reactome.org/PathwayBrowser/#/R-SSC-5638141 SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) IEA Sus scrofa A0A286ZJQ0 R-SSC-5638157 https://reactome.org/PathwayBrowser/#/R-SSC-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Sus scrofa A0A286ZJQ0 R-SSC-5638332 https://reactome.org/PathwayBrowser/#/R-SSC-5638332 PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) IEA Sus scrofa A0A286ZJQ0 R-SSC-5638333 https://reactome.org/PathwayBrowser/#/R-SSC-5638333 WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) IEA Sus scrofa A0A286ZJQ0 R-SSC-5649764 https://reactome.org/PathwayBrowser/#/R-SSC-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Sus scrofa A0A286ZJQ0 R-SSC-5649799 https://reactome.org/PathwayBrowser/#/R-SSC-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Sus scrofa A0A286ZJQ0 R-SSC-5649800 https://reactome.org/PathwayBrowser/#/R-SSC-5649800 WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) IEA Sus scrofa A0A286ZJQ0 R-SSC-5649801 https://reactome.org/PathwayBrowser/#/R-SSC-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Sus scrofa A0A286ZJQ0 R-SSC-5649802 https://reactome.org/PathwayBrowser/#/R-SSC-5649802 WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) IEA Sus scrofa A0A286ZJQ0 R-SSC-5661114 https://reactome.org/PathwayBrowser/#/R-SSC-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-5661115 https://reactome.org/PathwayBrowser/#/R-SSC-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-5661116 https://reactome.org/PathwayBrowser/#/R-SSC-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-5661117 https://reactome.org/PathwayBrowser/#/R-SSC-5661117 CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-5661120 https://reactome.org/PathwayBrowser/#/R-SSC-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-5661121 https://reactome.org/PathwayBrowser/#/R-SSC-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-5661122 https://reactome.org/PathwayBrowser/#/R-SSC-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-5661123 https://reactome.org/PathwayBrowser/#/R-SSC-5661123 KDM1A, KDM1B demethylate Me2K5-histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-73718 https://reactome.org/PathwayBrowser/#/R-SSC-73718 UBF-1 Binds rDNA Promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-74986 https://reactome.org/PathwayBrowser/#/R-SSC-74986 Elongation of pre-rRNA transcript IEA Sus scrofa A0A286ZJQ0 R-SSC-8865613 https://reactome.org/PathwayBrowser/#/R-SSC-8865613 BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3 IEA Sus scrofa A0A286ZJQ0 R-SSC-8936481 https://reactome.org/PathwayBrowser/#/R-SSC-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-8936584 https://reactome.org/PathwayBrowser/#/R-SSC-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-8936608 https://reactome.org/PathwayBrowser/#/R-SSC-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-8936621 https://reactome.org/PathwayBrowser/#/R-SSC-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-8937016 https://reactome.org/PathwayBrowser/#/R-SSC-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-8937022 https://reactome.org/PathwayBrowser/#/R-SSC-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-8937050 https://reactome.org/PathwayBrowser/#/R-SSC-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-8937113 https://reactome.org/PathwayBrowser/#/R-SSC-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-9009065 https://reactome.org/PathwayBrowser/#/R-SSC-9009065 FOXA1 and GATA3 bind to CCND1 promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-9009371 https://reactome.org/PathwayBrowser/#/R-SSC-9009371 Binding of AP1 transcriptional activator complexes to CCND1 promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-9011949 https://reactome.org/PathwayBrowser/#/R-SSC-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Sus scrofa A0A286ZJQ0 R-SSC-9011952 https://reactome.org/PathwayBrowser/#/R-SSC-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Sus scrofa A0A286ZJQ0 R-SSC-9011981 https://reactome.org/PathwayBrowser/#/R-SSC-9011981 EP300 is recruited to MYC and BCL2 genes IEA Sus scrofa A0A286ZJQ0 R-SSC-9011983 https://reactome.org/PathwayBrowser/#/R-SSC-9011983 Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes IEA Sus scrofa A0A286ZJQ0 R-SSC-9011984 https://reactome.org/PathwayBrowser/#/R-SSC-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Sus scrofa A0A286ZJQ0 R-SSC-9011985 https://reactome.org/PathwayBrowser/#/R-SSC-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Sus scrofa A0A286ZJQ0 R-SSC-9012000 https://reactome.org/PathwayBrowser/#/R-SSC-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Sus scrofa A0A286ZJQ0 R-SSC-9749197 https://reactome.org/PathwayBrowser/#/R-SSC-9749197 ORC1 binds to H4K20me2 IEA Sus scrofa A0A286ZJQ0 R-SSC-9842833 https://reactome.org/PathwayBrowser/#/R-SSC-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Sus scrofa A0A286ZJQ0 R-SSC-9843115 https://reactome.org/PathwayBrowser/#/R-SSC-9843115 Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci IEA Sus scrofa A0A286ZJQ0 R-SSC-9843117 https://reactome.org/PathwayBrowser/#/R-SSC-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Sus scrofa A0A286ZJQ0 R-SSC-9843118 https://reactome.org/PathwayBrowser/#/R-SSC-9843118 RXRA binds ligands IEA Sus scrofa A0A286ZJQ0 R-SSC-9843120 https://reactome.org/PathwayBrowser/#/R-SSC-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Sus scrofa A0A286ZJQ0 R-SSC-9844006 https://reactome.org/PathwayBrowser/#/R-SSC-9844006 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) IEA Sus scrofa A0A286ZJQ0 R-SSC-9844057 https://reactome.org/PathwayBrowser/#/R-SSC-9844057 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome IEA Sus scrofa A0A286ZJQ0 R-SSC-994106 https://reactome.org/PathwayBrowser/#/R-SSC-994106 HP1 alpha binds Histone H3K9(me)3 IEA Sus scrofa A0A286ZJQ0 R-SSC-997263 https://reactome.org/PathwayBrowser/#/R-SSC-997263 JMJD1C demethylates H3K9 mono- and di-methylation IEA Sus scrofa A0A286ZJQ9 R-SSC-202110 https://reactome.org/PathwayBrowser/#/R-SSC-202110 eNOS:Caveolin-1 complex binds to CaM IEA Sus scrofa A0A286ZJQ9 R-SSC-202129 https://reactome.org/PathwayBrowser/#/R-SSC-202129 HSP90 binds eNOS:Caveolin-1:CaM complex IEA Sus scrofa A0A286ZJQ9 R-SSC-202144 https://reactome.org/PathwayBrowser/#/R-SSC-202144 Caveolin-1 dissociates from eNOS:CaM:HSP90 complex IEA Sus scrofa A0A286ZJQ9 R-SSC-203565 https://reactome.org/PathwayBrowser/#/R-SSC-203565 eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP IEA Sus scrofa A0A286ZJQ9 R-SSC-203625 https://reactome.org/PathwayBrowser/#/R-SSC-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Sus scrofa A0A286ZJQ9 R-SSC-203662 https://reactome.org/PathwayBrowser/#/R-SSC-203662 eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 IEA Sus scrofa A0A286ZJQ9 R-SSC-203712 https://reactome.org/PathwayBrowser/#/R-SSC-203712 eNOS associates with Caveolin-1 IEA Sus scrofa A0A286ZJQ9 R-SSC-203716 https://reactome.org/PathwayBrowser/#/R-SSC-203716 eNOS:Caveolin-1 complex binds to Nostrin IEA Sus scrofa A0A286ZJQ9 R-SSC-204549 https://reactome.org/PathwayBrowser/#/R-SSC-204549 Caveolin-1 binds Basigin IEA Sus scrofa A0A286ZJQ9 R-SSC-5368596 https://reactome.org/PathwayBrowser/#/R-SSC-5368596 WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 IEA Sus scrofa A0A286ZJQ9 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJQ9 R-SSC-9013024 https://reactome.org/PathwayBrowser/#/R-SSC-9013024 RHOB binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJQ9 R-SSC-9013110 https://reactome.org/PathwayBrowser/#/R-SSC-9013110 RHOC binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJQ9 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJQ9 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJQ9 R-SSC-9013158 https://reactome.org/PathwayBrowser/#/R-SSC-9013158 CDC42 GDIs block activation of CDC42 IEA Sus scrofa A0A286ZJQ9 R-SSC-9014294 https://reactome.org/PathwayBrowser/#/R-SSC-9014294 RAC2 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJQ9 R-SSC-9014449 https://reactome.org/PathwayBrowser/#/R-SSC-9014449 RHOG binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJQ9 R-SSC-9018746 https://reactome.org/PathwayBrowser/#/R-SSC-9018746 RHOQ binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJQ9 R-SSC-9018758 https://reactome.org/PathwayBrowser/#/R-SSC-9018758 RHOH binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJQ9 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJQ9 R-SSC-9021068 https://reactome.org/PathwayBrowser/#/R-SSC-9021068 PalmS-ESRs bind CAVs IEA Sus scrofa A0A286ZJQ9 R-SSC-9021079 https://reactome.org/PathwayBrowser/#/R-SSC-9021079 PalmS-ESRs:CAVs translocate to plasma membrane IEA Sus scrofa A0A286ZJQ9 R-SSC-9693125 https://reactome.org/PathwayBrowser/#/R-SSC-9693125 RHOF binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJQ9 R-SSC-9693198 https://reactome.org/PathwayBrowser/#/R-SSC-9693198 RHOD binds effectors at the plasma membrane IEA Sus scrofa A0A286ZJQ9 R-SSC-9696266 https://reactome.org/PathwayBrowser/#/R-SSC-9696266 RND2 binds effectors IEA Sus scrofa A0A286ZJQ9 R-SSC-9696268 https://reactome.org/PathwayBrowser/#/R-SSC-9696268 RND3 binds effectors IEA Sus scrofa A0A286ZJQ9 R-SSC-9696271 https://reactome.org/PathwayBrowser/#/R-SSC-9696271 RND1 binds effectors IEA Sus scrofa A0A286ZJR1 R-SSC-8851619 https://reactome.org/PathwayBrowser/#/R-SSC-8851619 GALNT3 transfers GalNAc to FGF23 IEA Sus scrofa A0A286ZJR1 R-SSC-913675 https://reactome.org/PathwayBrowser/#/R-SSC-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Sus scrofa A0A286ZJR2 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A286ZJR2 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A286ZJR2 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A286ZJR2 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A286ZJR2 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A286ZJV3 R-SSC-8932221 https://reactome.org/PathwayBrowser/#/R-SSC-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Sus scrofa A0A286ZJV6 R-SSC-158750 https://reactome.org/PathwayBrowser/#/R-SSC-158750 crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin IEA Sus scrofa A0A286ZJV6 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A286ZJV6 R-SSC-9865167 https://reactome.org/PathwayBrowser/#/R-SSC-9865167 PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) IEA Sus scrofa A0A286ZJV6 R-SSC-9865184 https://reactome.org/PathwayBrowser/#/R-SSC-9865184 Phosphorylation of ABL1 on tyrosine-393 in response to oscillatory shear stress IEA Sus scrofa A0A286ZJV6 R-SSC-9865215 https://reactome.org/PathwayBrowser/#/R-SSC-9865215 p-S26-ANXA2 binds integrin alpha5:beta1 at the plasma membrane IEA Sus scrofa A0A286ZJV6 R-SSC-9865226 https://reactome.org/PathwayBrowser/#/R-SSC-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Sus scrofa A0A286ZJW8 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A286ZJW8 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A286ZJW8 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A286ZJW8 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A286ZJW9 R-SSC-5362412 https://reactome.org/PathwayBrowser/#/R-SSC-5362412 SYVN1 ubiquitinates Hh C-terminal fragments IEA Sus scrofa A0A286ZJW9 R-SSC-5362441 https://reactome.org/PathwayBrowser/#/R-SSC-5362441 C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane IEA Sus scrofa A0A286ZJW9 R-SSC-5362459 https://reactome.org/PathwayBrowser/#/R-SSC-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Sus scrofa A0A286ZJW9 R-SSC-8866542 https://reactome.org/PathwayBrowser/#/R-SSC-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Sus scrofa A0A286ZJW9 R-SSC-8866546 https://reactome.org/PathwayBrowser/#/R-SSC-8866546 RNF5 and RNF185 ubiquitinate misfolded CFTR IEA Sus scrofa A0A286ZJW9 R-SSC-8866551 https://reactome.org/PathwayBrowser/#/R-SSC-8866551 CFTR binds components of the ERAD machinery for ubiquitination and degradation IEA Sus scrofa A0A286ZJX8 R-SSC-8869206 https://reactome.org/PathwayBrowser/#/R-SSC-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Sus scrofa A0A286ZJY7 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A286ZJY7 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A286ZJY7 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A286ZJY7 R-SSC-6800426 https://reactome.org/PathwayBrowser/#/R-SSC-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Sus scrofa A0A286ZJZ7 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A286ZJZ7 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A286ZJZ7 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A286ZJZ7 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A286ZJZ7 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A286ZJZ7 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A286ZJZ7 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A286ZJZ7 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A286ZJZ7 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A286ZJZ7 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A286ZJZ7 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A286ZJZ9 R-SSC-110307 https://reactome.org/PathwayBrowser/#/R-SSC-110307 REV1 binds AP-dsDNA IEA Sus scrofa A0A286ZJZ9 R-SSC-110308 https://reactome.org/PathwayBrowser/#/R-SSC-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Sus scrofa A0A286ZJZ9 R-SSC-110311 https://reactome.org/PathwayBrowser/#/R-SSC-110311 POLZ extends translesion synthesis IEA Sus scrofa A0A286ZJZ9 R-SSC-110316 https://reactome.org/PathwayBrowser/#/R-SSC-110316 POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template IEA Sus scrofa A0A286ZJZ9 R-SSC-110317 https://reactome.org/PathwayBrowser/#/R-SSC-110317 Insertion of correct bases opposite the lesion by POLH IEA Sus scrofa A0A286ZJZ9 R-SSC-110319 https://reactome.org/PathwayBrowser/#/R-SSC-110319 Elongation by POLH IEA Sus scrofa A0A286ZJZ9 R-SSC-110364 https://reactome.org/PathwayBrowser/#/R-SSC-110364 PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 IEA Sus scrofa A0A286ZJZ9 R-SSC-110368 https://reactome.org/PathwayBrowser/#/R-SSC-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Sus scrofa A0A286ZJZ9 R-SSC-110371 https://reactome.org/PathwayBrowser/#/R-SSC-110371 LIG1 binds APEX1 and PCNA at SSB IEA Sus scrofa A0A286ZJZ9 R-SSC-174439 https://reactome.org/PathwayBrowser/#/R-SSC-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Sus scrofa A0A286ZJZ9 R-SSC-174447 https://reactome.org/PathwayBrowser/#/R-SSC-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Sus scrofa A0A286ZJZ9 R-SSC-174452 https://reactome.org/PathwayBrowser/#/R-SSC-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Sus scrofa A0A286ZJZ9 R-SSC-5651805 https://reactome.org/PathwayBrowser/#/R-SSC-5651805 LIG1 bound to APEX1 and PCNA ligates SSB IEA Sus scrofa A0A286ZJZ9 R-SSC-5652005 https://reactome.org/PathwayBrowser/#/R-SSC-5652005 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA IEA Sus scrofa A0A286ZJZ9 R-SSC-5652009 https://reactome.org/PathwayBrowser/#/R-SSC-5652009 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA IEA Sus scrofa A0A286ZJZ9 R-SSC-5652151 https://reactome.org/PathwayBrowser/#/R-SSC-5652151 REV1 recruits POLZ to (AP:Cyt)-DNA Template IEA Sus scrofa A0A286ZJZ9 R-SSC-5653754 https://reactome.org/PathwayBrowser/#/R-SSC-5653754 UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA IEA Sus scrofa A0A286ZJZ9 R-SSC-5653756 https://reactome.org/PathwayBrowser/#/R-SSC-5653756 TRIM25 binds monoUb:164-PCNA IEA Sus scrofa A0A286ZJZ9 R-SSC-5653766 https://reactome.org/PathwayBrowser/#/R-SSC-5653766 USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A286ZJZ9 R-SSC-5653770 https://reactome.org/PathwayBrowser/#/R-SSC-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A286ZJZ9 R-SSC-5653780 https://reactome.org/PathwayBrowser/#/R-SSC-5653780 USP43 binds ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A286ZJZ9 R-SSC-5653786 https://reactome.org/PathwayBrowser/#/R-SSC-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A286ZJZ9 R-SSC-5653838 https://reactome.org/PathwayBrowser/#/R-SSC-5653838 POLD,POLE binds deISGylated PCNA after TLS IEA Sus scrofa A0A286ZJZ9 R-SSC-5654985 https://reactome.org/PathwayBrowser/#/R-SSC-5654985 SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH IEA Sus scrofa A0A286ZJZ9 R-SSC-5654986 https://reactome.org/PathwayBrowser/#/R-SSC-5654986 SPRTN binds monoUb:K164-PCNA associated with POLH IEA Sus scrofa A0A286ZJZ9 R-SSC-5654989 https://reactome.org/PathwayBrowser/#/R-SSC-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Sus scrofa A0A286ZJZ9 R-SSC-5655466 https://reactome.org/PathwayBrowser/#/R-SSC-5655466 USP1:WDR48 deubiquitinates monoUb:K164-PCNA IEA Sus scrofa A0A286ZJZ9 R-SSC-5655481 https://reactome.org/PathwayBrowser/#/R-SSC-5655481 USP1:WDR48 binds monoUb:K164-PCNA IEA Sus scrofa A0A286ZJZ9 R-SSC-5655835 https://reactome.org/PathwayBrowser/#/R-SSC-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Sus scrofa A0A286ZJZ9 R-SSC-5655892 https://reactome.org/PathwayBrowser/#/R-SSC-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Sus scrofa A0A286ZJZ9 R-SSC-5655965 https://reactome.org/PathwayBrowser/#/R-SSC-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Sus scrofa A0A286ZJZ9 R-SSC-5656105 https://reactome.org/PathwayBrowser/#/R-SSC-5656105 POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA IEA Sus scrofa A0A286ZJZ9 R-SSC-5656148 https://reactome.org/PathwayBrowser/#/R-SSC-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Sus scrofa A0A286ZJZ9 R-SSC-5656158 https://reactome.org/PathwayBrowser/#/R-SSC-5656158 POLZ elongates POLI-incorporated dNMP IEA Sus scrofa A0A286ZJZ9 R-SSC-5690213 https://reactome.org/PathwayBrowser/#/R-SSC-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Sus scrofa A0A286ZJZ9 R-SSC-5690988 https://reactome.org/PathwayBrowser/#/R-SSC-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Sus scrofa A0A286ZJZ9 R-SSC-5691001 https://reactome.org/PathwayBrowser/#/R-SSC-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Sus scrofa A0A286ZJZ9 R-SSC-5693593 https://reactome.org/PathwayBrowser/#/R-SSC-5693593 D-loop extension by DNA polymerases IEA Sus scrofa A0A286ZJZ9 R-SSC-6782208 https://reactome.org/PathwayBrowser/#/R-SSC-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Sus scrofa A0A286ZJZ9 R-SSC-6782211 https://reactome.org/PathwayBrowser/#/R-SSC-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Sus scrofa A0A286ZJZ9 R-SSC-6782224 https://reactome.org/PathwayBrowser/#/R-SSC-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Sus scrofa A0A286ZJZ9 R-SSC-6782227 https://reactome.org/PathwayBrowser/#/R-SSC-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Sus scrofa A0A286ZJZ9 R-SSC-69053 https://reactome.org/PathwayBrowser/#/R-SSC-69053 RFC binding displaces Pol Alpha IEA Sus scrofa A0A286ZJZ9 R-SSC-69063 https://reactome.org/PathwayBrowser/#/R-SSC-69063 Loading of PCNA - Sliding Clamp Formation IEA Sus scrofa A0A286ZJZ9 R-SSC-69068 https://reactome.org/PathwayBrowser/#/R-SSC-69068 RFC dissociates after sliding clamp formation IEA Sus scrofa A0A286ZK20 R-SSC-1454916 https://reactome.org/PathwayBrowser/#/R-SSC-1454916 The ABCC family mediates organic anion transport IEA Sus scrofa A0A286ZK24 R-SSC-71163 https://reactome.org/PathwayBrowser/#/R-SSC-71163 HPD dioxygenates HPP IEA Sus scrofa A0A286ZK37 R-SSC-5692749 https://reactome.org/PathwayBrowser/#/R-SSC-5692749 CDC14A,B bind MAPK6 IEA Sus scrofa A0A286ZK37 R-SSC-5692754 https://reactome.org/PathwayBrowser/#/R-SSC-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Sus scrofa A0A286ZK37 R-SSC-5692764 https://reactome.org/PathwayBrowser/#/R-SSC-5692764 MAPK6 binds CCND3 IEA Sus scrofa A0A286ZK44 R-SSC-9854961 https://reactome.org/PathwayBrowser/#/R-SSC-9854961 SDHAF4 binds to FAD-SDHA IEA Sus scrofa A0A286ZK44 R-SSC-9855212 https://reactome.org/PathwayBrowser/#/R-SSC-9855212 SDHA binds to SDHB IEA Sus scrofa A0A286ZK45 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A286ZK57 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A286ZK57 R-SSC-444691 https://reactome.org/PathwayBrowser/#/R-SSC-444691 Prokineticin receptors bind prokineticin IEA Sus scrofa A0A286ZK57 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A286ZK57 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A286ZK62 R-SSC-6809011 https://reactome.org/PathwayBrowser/#/R-SSC-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Sus scrofa A0A286ZK62 R-SSC-6809014 https://reactome.org/PathwayBrowser/#/R-SSC-6809014 cis-Golgi cis-SNARE binds NSF and SNAPs IEA Sus scrofa A0A286ZK62 R-SSC-6809015 https://reactome.org/PathwayBrowser/#/R-SSC-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Sus scrofa A0A286ZK62 R-SSC-6811433 https://reactome.org/PathwayBrowser/#/R-SSC-6811433 The COG tethering complex interacts with numerous SNAREs at the Golgi membrane IEA Sus scrofa A0A286ZK62 R-SSC-8847637 https://reactome.org/PathwayBrowser/#/R-SSC-8847637 NSF and SNAPs bind the cis-SNARE at the Golgi IEA Sus scrofa A0A286ZK62 R-SSC-8847638 https://reactome.org/PathwayBrowser/#/R-SSC-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane IEA Sus scrofa A0A286ZK78 R-SSC-3318413 https://reactome.org/PathwayBrowser/#/R-SSC-3318413 KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 IEA Sus scrofa A0A286ZK85 R-SSC-425661 https://reactome.org/PathwayBrowser/#/R-SSC-425661 SLC8A1,2,3 exchange 3Na+ for Ca2+ IEA Sus scrofa A0A286ZK88 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A286ZK88 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa A0A286ZK88 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa A0A286ZK88 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A286ZK92 R-SSC-446391 https://reactome.org/PathwayBrowser/#/R-SSC-446391 Formation of the PINCH-ILK-parvin complex IEA Sus scrofa A0A286ZKA7 R-SSC-1955380 https://reactome.org/PathwayBrowser/#/R-SSC-1955380 TIMM9:TIMM10 transfers proteins to TIMM22 IEA Sus scrofa A0A286ZKB7 R-SSC-202165 https://reactome.org/PathwayBrowser/#/R-SSC-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Sus scrofa A0A286ZKB7 R-SSC-202168 https://reactome.org/PathwayBrowser/#/R-SSC-202168 Phosphorylation of ZAP-70 by Lck IEA Sus scrofa A0A286ZKB7 R-SSC-202174 https://reactome.org/PathwayBrowser/#/R-SSC-202174 Activation of ZAP-70 IEA Sus scrofa A0A286ZKB7 R-SSC-202214 https://reactome.org/PathwayBrowser/#/R-SSC-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Sus scrofa A0A286ZKB7 R-SSC-202216 https://reactome.org/PathwayBrowser/#/R-SSC-202216 Phosphorylation of SLP-76 IEA Sus scrofa A0A286ZKB7 R-SSC-202233 https://reactome.org/PathwayBrowser/#/R-SSC-202233 Inactivation of Lck by Csk IEA Sus scrofa A0A286ZKB7 R-SSC-202245 https://reactome.org/PathwayBrowser/#/R-SSC-202245 Phosphorylation of TBSMs in LAT IEA Sus scrofa A0A286ZKB7 R-SSC-202248 https://reactome.org/PathwayBrowser/#/R-SSC-202248 Phosphorylation of PLC-gamma1 IEA Sus scrofa A0A286ZKB7 R-SSC-202291 https://reactome.org/PathwayBrowser/#/R-SSC-202291 Activation of Lck IEA Sus scrofa A0A286ZKB7 R-SSC-202307 https://reactome.org/PathwayBrowser/#/R-SSC-202307 Change of PKC theta conformation IEA Sus scrofa A0A286ZKB7 R-SSC-2130336 https://reactome.org/PathwayBrowser/#/R-SSC-2130336 Initial proteolyis of Ii by aspartic proteases to lip22 IEA Sus scrofa A0A286ZKB7 R-SSC-2130349 https://reactome.org/PathwayBrowser/#/R-SSC-2130349 Generation of CLIP from lip10 IEA Sus scrofa A0A286ZKB7 R-SSC-2130378 https://reactome.org/PathwayBrowser/#/R-SSC-2130378 Transport of MHC II:Ii complex to plasma membrane IEA Sus scrofa A0A286ZKB7 R-SSC-2130393 https://reactome.org/PathwayBrowser/#/R-SSC-2130393 Transport of MHC II:Ii complex along Golgi to TGN IEA Sus scrofa A0A286ZKB7 R-SSC-2130478 https://reactome.org/PathwayBrowser/#/R-SSC-2130478 Interaction of invariant chain trimer and MHC II alpha beta dimer IEA Sus scrofa A0A286ZKB7 R-SSC-2130486 https://reactome.org/PathwayBrowser/#/R-SSC-2130486 Uncoating of clathrin-coated vesicles and fusion with endosomes IEA Sus scrofa A0A286ZKB7 R-SSC-2130500 https://reactome.org/PathwayBrowser/#/R-SSC-2130500 Insertion of MHC II:Ii complex in to the plasma membrane IEA Sus scrofa A0A286ZKB7 R-SSC-2130504 https://reactome.org/PathwayBrowser/#/R-SSC-2130504 Cleavage of lip22 to lip10 IEA Sus scrofa A0A286ZKB7 R-SSC-2130619 https://reactome.org/PathwayBrowser/#/R-SSC-2130619 TGN-lysosomal vesicle coat assembly IEA Sus scrofa A0A286ZKB7 R-SSC-2130640 https://reactome.org/PathwayBrowser/#/R-SSC-2130640 Recruitment of clathrin coated vesicle by Ii IEA Sus scrofa A0A286ZKB7 R-SSC-2130641 https://reactome.org/PathwayBrowser/#/R-SSC-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Sus scrofa A0A286ZKB7 R-SSC-2130725 https://reactome.org/PathwayBrowser/#/R-SSC-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Sus scrofa A0A286ZKB7 R-SSC-2130731 https://reactome.org/PathwayBrowser/#/R-SSC-2130731 Formation of COPII vesicle IEA Sus scrofa A0A286ZKB7 R-SSC-2213235 https://reactome.org/PathwayBrowser/#/R-SSC-2213235 Trafficking of nonameric complex in the endocytic pathway IEA Sus scrofa A0A286ZKB7 R-SSC-2213236 https://reactome.org/PathwayBrowser/#/R-SSC-2213236 TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome IEA Sus scrofa A0A286ZKB7 R-SSC-2213239 https://reactome.org/PathwayBrowser/#/R-SSC-2213239 Formation of MHC II alpha beta heterodimer IEA Sus scrofa A0A286ZKB7 R-SSC-2213241 https://reactome.org/PathwayBrowser/#/R-SSC-2213241 Formation of nonameric complex IEA Sus scrofa A0A286ZKB7 R-SSC-2213243 https://reactome.org/PathwayBrowser/#/R-SSC-2213243 Fusion of COPII vesicle with Golgi complex IEA Sus scrofa A0A286ZKB7 R-SSC-2213244 https://reactome.org/PathwayBrowser/#/R-SSC-2213244 Loading of antigenic peptides IEA Sus scrofa A0A286ZKB7 R-SSC-2213246 https://reactome.org/PathwayBrowser/#/R-SSC-2213246 Disassociation of CLIP from MHC II IEA Sus scrofa A0A286ZKB7 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A286ZKB7 R-SSC-389758 https://reactome.org/PathwayBrowser/#/R-SSC-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Sus scrofa A0A286ZKB7 R-SSC-8852200 https://reactome.org/PathwayBrowser/#/R-SSC-8852200 Inactivation of LCK by PTPN22 IEA Sus scrofa A0A286ZKB7 R-SSC-8855381 https://reactome.org/PathwayBrowser/#/R-SSC-8855381 PTPN22 dephosphorylates ZAP70 IEA Sus scrofa A0A286ZKB7 R-SSC-8856157 https://reactome.org/PathwayBrowser/#/R-SSC-8856157 LAG3 (CD233) binds MHC II IEA Sus scrofa A0A286ZKB7 R-SSC-8951498 https://reactome.org/PathwayBrowser/#/R-SSC-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Sus scrofa A0A286ZKB7 R-SSC-8951500 https://reactome.org/PathwayBrowser/#/R-SSC-8951500 Dissociation of CANX from nonameric complex IEA Sus scrofa A0A286ZKC5 R-SSC-1306876 https://reactome.org/PathwayBrowser/#/R-SSC-1306876 NLRP3 activation by small molecules IEA Sus scrofa A0A286ZKC5 R-SSC-3371503 https://reactome.org/PathwayBrowser/#/R-SSC-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Sus scrofa A0A286ZKC5 R-SSC-3371586 https://reactome.org/PathwayBrowser/#/R-SSC-3371586 Dissociation of cytosolic HSF1:HSP90 complex IEA Sus scrofa A0A286ZKC5 R-SSC-419644 https://reactome.org/PathwayBrowser/#/R-SSC-419644 Transphosphorylation of pLIMK1 IEA Sus scrofa A0A286ZKC5 R-SSC-419645 https://reactome.org/PathwayBrowser/#/R-SSC-419645 Dimerization of LIMK1 by Hsp90 IEA Sus scrofa A0A286ZKC5 R-SSC-5082356 https://reactome.org/PathwayBrowser/#/R-SSC-5082356 HSF1-mediated gene expression IEA Sus scrofa A0A286ZKC5 R-SSC-5082409 https://reactome.org/PathwayBrowser/#/R-SSC-5082409 Dissociation of HSF1:HSP90 complex in the nucleus IEA Sus scrofa A0A286ZKC5 R-SSC-5324617 https://reactome.org/PathwayBrowser/#/R-SSC-5324617 HSP90:FKBP4:PTGES3 binds HSF1 trimer IEA Sus scrofa A0A286ZKC5 R-SSC-5324632 https://reactome.org/PathwayBrowser/#/R-SSC-5324632 Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates IEA Sus scrofa A0A286ZKC5 R-SSC-5618073 https://reactome.org/PathwayBrowser/#/R-SSC-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Sus scrofa A0A286ZKC5 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa A0A286ZKC5 R-SSC-5618085 https://reactome.org/PathwayBrowser/#/R-SSC-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Sus scrofa A0A286ZKC5 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa A0A286ZKC5 R-SSC-5618098 https://reactome.org/PathwayBrowser/#/R-SSC-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Sus scrofa A0A286ZKC5 R-SSC-5618099 https://reactome.org/PathwayBrowser/#/R-SSC-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Sus scrofa A0A286ZKC5 R-SSC-5618105 https://reactome.org/PathwayBrowser/#/R-SSC-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Sus scrofa A0A286ZKC5 R-SSC-5618107 https://reactome.org/PathwayBrowser/#/R-SSC-5618107 ATP binding to HSP90 triggers conformation change IEA Sus scrofa A0A286ZKC5 R-SSC-5618110 https://reactome.org/PathwayBrowser/#/R-SSC-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Sus scrofa A0A286ZKC5 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A286ZKC5 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A286ZKC5 R-SSC-873951 https://reactome.org/PathwayBrowser/#/R-SSC-873951 SGT1:HSP90 binds inactive NLRP3 IEA Sus scrofa A0A286ZKC5 R-SSC-874087 https://reactome.org/PathwayBrowser/#/R-SSC-874087 SGT1 binds HSP90 IEA Sus scrofa A0A286ZKC5 R-SSC-8852362 https://reactome.org/PathwayBrowser/#/R-SSC-8852362 GTSE1 binds CDKN1A IEA Sus scrofa A0A286ZKC5 R-SSC-8936849 https://reactome.org/PathwayBrowser/#/R-SSC-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Sus scrofa A0A286ZKC5 R-SSC-8937169 https://reactome.org/PathwayBrowser/#/R-SSC-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Sus scrofa A0A286ZKC5 R-SSC-8937191 https://reactome.org/PathwayBrowser/#/R-SSC-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates IEA Sus scrofa A0A286ZKC5 R-SSC-8939204 https://reactome.org/PathwayBrowser/#/R-SSC-8939204 ESTG binds ESR1:chaperone complex IEA Sus scrofa A0A286ZKC5 R-SSC-9018785 https://reactome.org/PathwayBrowser/#/R-SSC-9018785 RHOBTB2 binds GTP IEA Sus scrofa A0A286ZKC5 R-SSC-9038161 https://reactome.org/PathwayBrowser/#/R-SSC-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Sus scrofa A0A286ZKC5 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa A0A286ZKC5 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa A0A286ZKC5 R-SSC-9705925 https://reactome.org/PathwayBrowser/#/R-SSC-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Sus scrofa A0A286ZKC5 R-SSC-9705926 https://reactome.org/PathwayBrowser/#/R-SSC-9705926 AR binds AR agonists IEA Sus scrofa A0A286ZKC5 R-SSC-9706837 https://reactome.org/PathwayBrowser/#/R-SSC-9706837 AR binds AR antagonists IEA Sus scrofa A0A286ZKC5 R-SSC-9709547 https://reactome.org/PathwayBrowser/#/R-SSC-9709547 ESTG binds ESR2:chaperone complex IEA Sus scrofa A0A286ZKC5 R-SSC-9709831 https://reactome.org/PathwayBrowser/#/R-SSC-9709831 HSP90 binds TBK1 and IRF3 IEA Sus scrofa A0A286ZKC5 R-SSC-9716913 https://reactome.org/PathwayBrowser/#/R-SSC-9716913 ESR1 binds ESR1 antagonists IEA Sus scrofa A0A286ZKC5 R-SSC-9716947 https://reactome.org/PathwayBrowser/#/R-SSC-9716947 ESR1 binds ESR1 agonists IEA Sus scrofa A0A286ZKC5 R-SSC-9725855 https://reactome.org/PathwayBrowser/#/R-SSC-9725855 NR3C2 binds NR3C2 antagonists IEA Sus scrofa A0A286ZKC5 R-SSC-9725885 https://reactome.org/PathwayBrowser/#/R-SSC-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Sus scrofa A0A286ZKC5 R-SSC-9726509 https://reactome.org/PathwayBrowser/#/R-SSC-9726509 NR3C2 binds fludrocortisone IEA Sus scrofa A0A286ZKC5 R-SSC-9726580 https://reactome.org/PathwayBrowser/#/R-SSC-9726580 PGR binds PGR agonists IEA Sus scrofa A0A286ZKC5 R-SSC-9726621 https://reactome.org/PathwayBrowser/#/R-SSC-9726621 PGR binds PGR antagonists IEA Sus scrofa A0A286ZKC7 R-SSC-6785126 https://reactome.org/PathwayBrowser/#/R-SSC-6785126 FA core complex assembles at DNA interstrand crosslinks (ICLs) IEA Sus scrofa A0A286ZKC7 R-SSC-6785342 https://reactome.org/PathwayBrowser/#/R-SSC-6785342 FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex IEA Sus scrofa A0A286ZKC7 R-SSC-6785361 https://reactome.org/PathwayBrowser/#/R-SSC-6785361 Monoubiquitination of FANCD2:FANCI IEA Sus scrofa A0A286ZKC7 R-SSC-6785732 https://reactome.org/PathwayBrowser/#/R-SSC-6785732 DNA nucleases bind monoubiquitinated ID2 complex IEA Sus scrofa A0A286ZKC7 R-SSC-6785986 https://reactome.org/PathwayBrowser/#/R-SSC-6785986 DNA nucleases unhook the interstrand crosslink (ICL) IEA Sus scrofa A0A286ZKC7 R-SSC-6786155 https://reactome.org/PathwayBrowser/#/R-SSC-6786155 POLN binds ICL-DNA IEA Sus scrofa A0A286ZKC7 R-SSC-6786166 https://reactome.org/PathwayBrowser/#/R-SSC-6786166 Translesion synthesis across unhooked ICL by POLN IEA Sus scrofa A0A286ZKC7 R-SSC-6786171 https://reactome.org/PathwayBrowser/#/R-SSC-6786171 FANCD2 deubiquitination by USP1:WDR48 IEA Sus scrofa A0A286ZKC7 R-SSC-6788385 https://reactome.org/PathwayBrowser/#/R-SSC-6788385 The complex of ATR and ATRIP is recruited to ICL-DNA IEA Sus scrofa A0A286ZKC7 R-SSC-6788392 https://reactome.org/PathwayBrowser/#/R-SSC-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Sus scrofa A0A286ZKC7 R-SSC-9835411 https://reactome.org/PathwayBrowser/#/R-SSC-9835411 FA core complex:HSP70s binds PKR IEA Sus scrofa A0A286ZKD3 R-SSC-6781814 https://reactome.org/PathwayBrowser/#/R-SSC-6781814 USP19 deubiquitinates RNF123 IEA Sus scrofa A0A286ZKD3 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZKD3 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A286ZKD3 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZKD3 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A286ZKD4 R-SSC-372448 https://reactome.org/PathwayBrowser/#/R-SSC-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Sus scrofa A0A286ZKD5 R-SSC-264615 https://reactome.org/PathwayBrowser/#/R-SSC-264615 Loading of acetylcholine in synaptic vesicles IEA Sus scrofa A0A286ZKD5 R-SSC-372505 https://reactome.org/PathwayBrowser/#/R-SSC-372505 Acetylcholine synaptic vesicle docking and priming IEA Sus scrofa A0A286ZKD5 R-SSC-372529 https://reactome.org/PathwayBrowser/#/R-SSC-372529 Release of acetylcholine at the synapse IEA Sus scrofa A0A286ZKD5 R-SSC-8866277 https://reactome.org/PathwayBrowser/#/R-SSC-8866277 AP-2 directly binds some endocytic cargo IEA Sus scrofa A0A286ZKD5 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A286ZKD5 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A286ZKD5 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A286ZKD5 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A286ZKD5 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A286ZKD5 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A286ZKD5 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A286ZKD5 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A286ZKD5 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A286ZKD5 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A286ZKD5 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A286ZKD5 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A286ZKD5 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A286ZKD5 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A286ZKD7 R-SSC-165680 https://reactome.org/PathwayBrowser/#/R-SSC-165680 Formation of active mTORC1 complex IEA Sus scrofa A0A286ZKD7 R-SSC-165692 https://reactome.org/PathwayBrowser/#/R-SSC-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Sus scrofa A0A286ZKD7 R-SSC-165718 https://reactome.org/PathwayBrowser/#/R-SSC-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Sus scrofa A0A286ZKD7 R-SSC-380979 https://reactome.org/PathwayBrowser/#/R-SSC-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Sus scrofa A0A286ZKD7 R-SSC-447074 https://reactome.org/PathwayBrowser/#/R-SSC-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Sus scrofa A0A286ZKD7 R-SSC-5653957 https://reactome.org/PathwayBrowser/#/R-SSC-5653957 Rag dimer formation IEA Sus scrofa A0A286ZKD7 R-SSC-5653968 https://reactome.org/PathwayBrowser/#/R-SSC-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Sus scrofa A0A286ZKD7 R-SSC-5653974 https://reactome.org/PathwayBrowser/#/R-SSC-5653974 Ragulator binds Rag dimers IEA Sus scrofa A0A286ZKD7 R-SSC-5672010 https://reactome.org/PathwayBrowser/#/R-SSC-5672010 Active MTORC1 phosphorylates ULK1 IEA Sus scrofa A0A286ZKD7 R-SSC-5672017 https://reactome.org/PathwayBrowser/#/R-SSC-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Sus scrofa A0A286ZKD7 R-SSC-5672817 https://reactome.org/PathwayBrowser/#/R-SSC-5672817 Active MTORC1 binds the ULK1 complex IEA Sus scrofa A0A286ZKD7 R-SSC-5672824 https://reactome.org/PathwayBrowser/#/R-SSC-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Sus scrofa A0A286ZKD7 R-SSC-5672828 https://reactome.org/PathwayBrowser/#/R-SSC-5672828 mTORC1 phosphorylates AKT1S1 IEA Sus scrofa A0A286ZKD7 R-SSC-5672843 https://reactome.org/PathwayBrowser/#/R-SSC-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Sus scrofa A0A286ZKD7 R-SSC-5673768 https://reactome.org/PathwayBrowser/#/R-SSC-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Sus scrofa A0A286ZKD7 R-SSC-5675790 https://reactome.org/PathwayBrowser/#/R-SSC-5675790 MTORC1 dissociates from ULK complex IEA Sus scrofa A0A286ZKD7 R-SSC-8944454 https://reactome.org/PathwayBrowser/#/R-SSC-8944454 mTORC1 phosphorylates MAF1 IEA Sus scrofa A0A286ZKD7 R-SSC-8944457 https://reactome.org/PathwayBrowser/#/R-SSC-8944457 MAF1 translocates to the nucleus IEA Sus scrofa A0A286ZKD7 R-SSC-8952716 https://reactome.org/PathwayBrowser/#/R-SSC-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Sus scrofa A0A286ZKD7 R-SSC-8952726 https://reactome.org/PathwayBrowser/#/R-SSC-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Sus scrofa A0A286ZKD7 R-SSC-9639286 https://reactome.org/PathwayBrowser/#/R-SSC-9639286 RRAGC,D exchanges GTP for GDP IEA Sus scrofa A0A286ZKD7 R-SSC-9640167 https://reactome.org/PathwayBrowser/#/R-SSC-9640167 RRAGA,B exchanges GDP for GTP IEA Sus scrofa A0A286ZKD7 R-SSC-9640168 https://reactome.org/PathwayBrowser/#/R-SSC-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Sus scrofa A0A286ZKD7 R-SSC-9640175 https://reactome.org/PathwayBrowser/#/R-SSC-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Sus scrofa A0A286ZKD7 R-SSC-9640195 https://reactome.org/PathwayBrowser/#/R-SSC-9640195 RRAGA,B hydrolyzes GTP IEA Sus scrofa A0A286ZKD7 R-SSC-9645598 https://reactome.org/PathwayBrowser/#/R-SSC-9645598 RRAGC,D hydrolyzes GTP IEA Sus scrofa A0A286ZKD7 R-SSC-9645608 https://reactome.org/PathwayBrowser/#/R-SSC-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Sus scrofa A0A286ZKD7 R-SSC-9646468 https://reactome.org/PathwayBrowser/#/R-SSC-9646468 mTORC1 binds RHEB:GTP IEA Sus scrofa A0A286ZKE4 R-SSC-72180 https://reactome.org/PathwayBrowser/#/R-SSC-72180 Cleavage of mRNA at the 3'-end IEA Sus scrofa A0A286ZKE4 R-SSC-72231 https://reactome.org/PathwayBrowser/#/R-SSC-72231 Formation of the Cleavage and Polyadenylation Complex IEA Sus scrofa A0A286ZKE4 R-SSC-77591 https://reactome.org/PathwayBrowser/#/R-SSC-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Sus scrofa A0A286ZKE4 R-SSC-77592 https://reactome.org/PathwayBrowser/#/R-SSC-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Sus scrofa A0A286ZKE4 R-SSC-77593 https://reactome.org/PathwayBrowser/#/R-SSC-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Sus scrofa A0A286ZKE4 R-SSC-8849157 https://reactome.org/PathwayBrowser/#/R-SSC-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Sus scrofa A0A286ZKF4 R-SSC-622326 https://reactome.org/PathwayBrowser/#/R-SSC-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Sus scrofa A0A286ZKF4 R-SSC-629595 https://reactome.org/PathwayBrowser/#/R-SSC-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Sus scrofa A0A286ZKF4 R-SSC-629596 https://reactome.org/PathwayBrowser/#/R-SSC-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Sus scrofa A0A286ZKF4 R-SSC-629599 https://reactome.org/PathwayBrowser/#/R-SSC-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Sus scrofa A0A286ZKI4 R-SSC-1296127 https://reactome.org/PathwayBrowser/#/R-SSC-1296127 Activation of voltage gated Potassium channels IEA Sus scrofa A0A286ZKL1 R-SSC-143468 https://reactome.org/PathwayBrowser/#/R-SSC-143468 MEOS oxidizes ethanol to acetaldehyde IEA Sus scrofa A0A286ZKL1 R-SSC-211881 https://reactome.org/PathwayBrowser/#/R-SSC-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Sus scrofa A0A286ZKL1 R-SSC-211910 https://reactome.org/PathwayBrowser/#/R-SSC-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Sus scrofa A0A286ZKL1 R-SSC-211929 https://reactome.org/PathwayBrowser/#/R-SSC-211929 CYP2C19 5-hydroxylates omeprazole IEA Sus scrofa A0A286ZKL1 R-SSC-211983 https://reactome.org/PathwayBrowser/#/R-SSC-211983 CYP2J2 oxidises ARA IEA Sus scrofa A0A286ZKL1 R-SSC-211988 https://reactome.org/PathwayBrowser/#/R-SSC-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Sus scrofa A0A286ZKL1 R-SSC-211991 https://reactome.org/PathwayBrowser/#/R-SSC-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Sus scrofa A0A286ZKL1 R-SSC-212005 https://reactome.org/PathwayBrowser/#/R-SSC-212005 CYP2F1 dehydrogenates 3-methylindole IEA Sus scrofa A0A286ZKL1 R-SSC-76354 https://reactome.org/PathwayBrowser/#/R-SSC-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Sus scrofa A0A286ZKL1 R-SSC-76397 https://reactome.org/PathwayBrowser/#/R-SSC-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Sus scrofa A0A286ZKL1 R-SSC-76416 https://reactome.org/PathwayBrowser/#/R-SSC-76416 Benzene is hydroxylated to phenol IEA Sus scrofa A0A286ZKL1 R-SSC-76434 https://reactome.org/PathwayBrowser/#/R-SSC-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Sus scrofa A0A286ZKL1 R-SSC-76475 https://reactome.org/PathwayBrowser/#/R-SSC-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Sus scrofa A0A286ZKL1 R-SSC-9680865 https://reactome.org/PathwayBrowser/#/R-SSC-9680865 CYP3A4, CYP2B6 bind ritonavir IEA Sus scrofa A0A286ZKL2 R-SSC-6799199 https://reactome.org/PathwayBrowser/#/R-SSC-6799199 COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex IEA Sus scrofa A0A286ZKL8 R-SSC-5694082 https://reactome.org/PathwayBrowser/#/R-SSC-5694082 XK:KEL:Zn2+ cleaves EDN3 IEA Sus scrofa A0A286ZKN1 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A286ZKN1 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A286ZKN1 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A286ZKN1 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZKN1 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A286ZKN1 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZKN1 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A286ZKN5 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A286ZKP1 R-SSC-2993780 https://reactome.org/PathwayBrowser/#/R-SSC-2993780 Transfer of SUMO1 from E1 to UBE2I (UBC9) IEA Sus scrofa A0A286ZKR5 R-SSC-429860 https://reactome.org/PathwayBrowser/#/R-SSC-429860 DCP1-DCP2 complex decaps mRNA IEA Sus scrofa A0A286ZKR5 R-SSC-429978 https://reactome.org/PathwayBrowser/#/R-SSC-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Sus scrofa A0A286ZKR5 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A286ZKR7 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A286ZKR7 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A286ZKR7 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A286ZKR7 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A286ZKR7 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A286ZKR7 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A286ZKR7 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A286ZKR7 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A286ZKR7 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A286ZKR7 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZKR7 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A286ZKR7 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A286ZKR7 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A286ZKR7 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A286ZKR7 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A286ZKR7 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A286ZKR7 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A286ZKR7 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A286ZKR7 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A286ZKR7 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A286ZKR7 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A286ZKR7 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A286ZKR7 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A286ZKR7 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A286ZKR7 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A286ZKR7 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A286ZKR7 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A286ZKR7 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A286ZKR7 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A286ZKR7 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A286ZKR7 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A286ZKR7 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A286ZKR7 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A286ZKR7 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A286ZKR7 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A286ZKR7 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A286ZKR7 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A286ZKR7 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A286ZKR7 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A286ZKR7 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A286ZKR7 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A286ZKR7 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A286ZKR7 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A286ZKR7 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A286ZKR7 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A286ZKR7 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A286ZKR7 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A286ZKR9 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A286ZKR9 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A286ZKS3 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A286ZKS3 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A286ZKS3 R-SSC-5218811 https://reactome.org/PathwayBrowser/#/R-SSC-5218811 DOCK180:ELMO binds CRK IEA Sus scrofa A0A286ZKS3 R-SSC-5218839 https://reactome.org/PathwayBrowser/#/R-SSC-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Sus scrofa A0A286ZKS3 R-SSC-8848611 https://reactome.org/PathwayBrowser/#/R-SSC-8848611 Phosphorylated PXN recruits the CRK complex IEA Sus scrofa A0A286ZKS3 R-SSC-8848618 https://reactome.org/PathwayBrowser/#/R-SSC-8848618 Activation of RAC1 by the PXN:CRK complex IEA Sus scrofa A0A286ZKS3 R-SSC-9014449 https://reactome.org/PathwayBrowser/#/R-SSC-9014449 RHOG binds effectors at the plasma membrane IEA Sus scrofa A0A286ZKU3 R-SSC-1632857 https://reactome.org/PathwayBrowser/#/R-SSC-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Sus scrofa A0A286ZKU3 R-SSC-5665868 https://reactome.org/PathwayBrowser/#/R-SSC-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Sus scrofa A0A286ZKU3 R-SSC-5672008 https://reactome.org/PathwayBrowser/#/R-SSC-5672008 Thr-180 of ULK1 is phosphorylated IEA Sus scrofa A0A286ZKU3 R-SSC-5672010 https://reactome.org/PathwayBrowser/#/R-SSC-5672010 Active MTORC1 phosphorylates ULK1 IEA Sus scrofa A0A286ZKU3 R-SSC-5672011 https://reactome.org/PathwayBrowser/#/R-SSC-5672011 p-AMPK:AMP binds the ULK complex IEA Sus scrofa A0A286ZKU3 R-SSC-5672817 https://reactome.org/PathwayBrowser/#/R-SSC-5672817 Active MTORC1 binds the ULK1 complex IEA Sus scrofa A0A286ZKU3 R-SSC-5673768 https://reactome.org/PathwayBrowser/#/R-SSC-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Sus scrofa A0A286ZKU3 R-SSC-5675790 https://reactome.org/PathwayBrowser/#/R-SSC-5675790 MTORC1 dissociates from ULK complex IEA Sus scrofa A0A286ZKU3 R-SSC-5675868 https://reactome.org/PathwayBrowser/#/R-SSC-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Sus scrofa A0A286ZKU3 R-SSC-5679205 https://reactome.org/PathwayBrowser/#/R-SSC-5679205 ULK1 phosphorylates Beclin-1 IEA Sus scrofa A0A286ZKU3 R-SSC-5679239 https://reactome.org/PathwayBrowser/#/R-SSC-5679239 ULK complex translocates to the ER IEA Sus scrofa A0A286ZKU3 R-SSC-5683925 https://reactome.org/PathwayBrowser/#/R-SSC-5683925 ULK1 is dephosphorylated IEA Sus scrofa A0A286ZKU4 R-SSC-68712 https://reactome.org/PathwayBrowser/#/R-SSC-68712 The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 IEA Sus scrofa A0A286ZKU4 R-SSC-68825 https://reactome.org/PathwayBrowser/#/R-SSC-68825 Ubiquitinated geminin is degraded by the proteasome IEA Sus scrofa A0A286ZKU4 R-SSC-69299 https://reactome.org/PathwayBrowser/#/R-SSC-69299 CDT1 binds geminin IEA Sus scrofa A0A286ZKV3 R-SSC-428052 https://reactome.org/PathwayBrowser/#/R-SSC-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Sus scrofa A0A286ZKW5 R-SSC-188467 https://reactome.org/PathwayBrowser/#/R-SSC-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) IEA Sus scrofa A0A286ZKX9 R-SSC-8982012 https://reactome.org/PathwayBrowser/#/R-SSC-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Sus scrofa A0A286ZKX9 R-SSC-8982017 https://reactome.org/PathwayBrowser/#/R-SSC-8982017 Active G alpha (q) binds RGS proteins IEA Sus scrofa A0A286ZKX9 R-SSC-8982019 https://reactome.org/PathwayBrowser/#/R-SSC-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Sus scrofa A0A286ZKX9 R-SSC-8982020 https://reactome.org/PathwayBrowser/#/R-SSC-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Sus scrofa A0A286ZKX9 R-SSC-8982025 https://reactome.org/PathwayBrowser/#/R-SSC-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Sus scrofa A0A286ZKX9 R-SSC-8982026 https://reactome.org/PathwayBrowser/#/R-SSC-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Sus scrofa A0A286ZKY8 R-SSC-5694409 https://reactome.org/PathwayBrowser/#/R-SSC-5694409 Nucleotide exchange on RAB1 IEA Sus scrofa A0A286ZKY8 R-SSC-5694418 https://reactome.org/PathwayBrowser/#/R-SSC-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Sus scrofa A0A286ZKZ0 R-SSC-6805546 https://reactome.org/PathwayBrowser/#/R-SSC-6805546 Keratin type I binds keratin type II IEA Sus scrofa A0A286ZKZ0 R-SSC-6805573 https://reactome.org/PathwayBrowser/#/R-SSC-6805573 Keratin type I/type II heterodimers form tetramers IEA Sus scrofa A0A286ZKZ0 R-SSC-6806610 https://reactome.org/PathwayBrowser/#/R-SSC-6806610 Keratin filament formation IEA Sus scrofa A0A286ZKZ0 R-SSC-6806613 https://reactome.org/PathwayBrowser/#/R-SSC-6806613 Keratin tetramers bind to form unit length filaments IEA Sus scrofa A0A286ZKZ0 R-SSC-6806629 https://reactome.org/PathwayBrowser/#/R-SSC-6806629 Formation of tonofilament bundles IEA Sus scrofa A0A286ZKZ0 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A286ZKZ0 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A286ZKZ0 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A286ZKZ0 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A286ZL06 R-SSC-5684081 https://reactome.org/PathwayBrowser/#/R-SSC-5684081 MRN complex binds CDK2 and RBBP8 IEA Sus scrofa A0A286ZL06 R-SSC-5684096 https://reactome.org/PathwayBrowser/#/R-SSC-5684096 CDK2 phosphorylates RBBP8 IEA Sus scrofa A0A286ZL06 R-SSC-5684108 https://reactome.org/PathwayBrowser/#/R-SSC-5684108 BRCA1 binds phosphorylated RBBP8 IEA Sus scrofa A0A286ZL06 R-SSC-5684140 https://reactome.org/PathwayBrowser/#/R-SSC-5684140 ATM phosphorylates RBBP8 IEA Sus scrofa A0A286ZL06 R-SSC-5684875 https://reactome.org/PathwayBrowser/#/R-SSC-5684875 Binding of ATR:ATRIP to RPA at resected DNA DSBs IEA Sus scrofa A0A286ZL06 R-SSC-5684882 https://reactome.org/PathwayBrowser/#/R-SSC-5684882 CHEK1 is recruited to resected DNA DSBs IEA Sus scrofa A0A286ZL06 R-SSC-5684887 https://reactome.org/PathwayBrowser/#/R-SSC-5684887 Activation of CHEK1 at resected DNA DSBs IEA Sus scrofa A0A286ZL06 R-SSC-5685011 https://reactome.org/PathwayBrowser/#/R-SSC-5685011 ATR activation at DNA DSBs IEA Sus scrofa A0A286ZL06 R-SSC-5685156 https://reactome.org/PathwayBrowser/#/R-SSC-5685156 ATR phosphorylates RPA2 IEA Sus scrofa A0A286ZL06 R-SSC-5685341 https://reactome.org/PathwayBrowser/#/R-SSC-5685341 BCDX2 complex stabilizes RAD51 filament IEA Sus scrofa A0A286ZL06 R-SSC-5685838 https://reactome.org/PathwayBrowser/#/R-SSC-5685838 CX3 complex binds D-loop structures IEA Sus scrofa A0A286ZL06 R-SSC-5685953 https://reactome.org/PathwayBrowser/#/R-SSC-5685953 SIRT6 deacetylates RBBP8 IEA Sus scrofa A0A286ZL06 R-SSC-5685985 https://reactome.org/PathwayBrowser/#/R-SSC-5685985 EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment IEA Sus scrofa A0A286ZL06 R-SSC-5685994 https://reactome.org/PathwayBrowser/#/R-SSC-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Sus scrofa A0A286ZL06 R-SSC-5686440 https://reactome.org/PathwayBrowser/#/R-SSC-5686440 MUS81:EME1,EME2 cleaves D-loop IEA Sus scrofa A0A286ZL06 R-SSC-5686642 https://reactome.org/PathwayBrowser/#/R-SSC-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Sus scrofa A0A286ZL06 R-SSC-5686657 https://reactome.org/PathwayBrowser/#/R-SSC-5686657 ERCC1:XPF cleaves flaps generated by SSA IEA Sus scrofa A0A286ZL06 R-SSC-5687464 https://reactome.org/PathwayBrowser/#/R-SSC-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Sus scrofa A0A286ZL06 R-SSC-5687465 https://reactome.org/PathwayBrowser/#/R-SSC-5687465 MRN complex binds RBBP8 IEA Sus scrofa A0A286ZL06 R-SSC-5687484 https://reactome.org/PathwayBrowser/#/R-SSC-5687484 PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site IEA Sus scrofa A0A286ZL06 R-SSC-5687640 https://reactome.org/PathwayBrowser/#/R-SSC-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Sus scrofa A0A286ZL06 R-SSC-5687653 https://reactome.org/PathwayBrowser/#/R-SSC-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Sus scrofa A0A286ZL06 R-SSC-5687664 https://reactome.org/PathwayBrowser/#/R-SSC-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Sus scrofa A0A286ZL06 R-SSC-5687673 https://reactome.org/PathwayBrowser/#/R-SSC-5687673 MRN recruits LIG3:XRCC1 to MMEJ sites IEA Sus scrofa A0A286ZL06 R-SSC-5687675 https://reactome.org/PathwayBrowser/#/R-SSC-5687675 LIG3 ligates remaining SSBs in MMEJ IEA Sus scrofa A0A286ZL06 R-SSC-5693539 https://reactome.org/PathwayBrowser/#/R-SSC-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Sus scrofa A0A286ZL06 R-SSC-5693542 https://reactome.org/PathwayBrowser/#/R-SSC-5693542 Association of RPA complexes with ssDNA at resected DNA DSBs IEA Sus scrofa A0A286ZL06 R-SSC-5693564 https://reactome.org/PathwayBrowser/#/R-SSC-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Sus scrofa A0A286ZL06 R-SSC-5693580 https://reactome.org/PathwayBrowser/#/R-SSC-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Sus scrofa A0A286ZL06 R-SSC-5693584 https://reactome.org/PathwayBrowser/#/R-SSC-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Sus scrofa A0A286ZL06 R-SSC-5693593 https://reactome.org/PathwayBrowser/#/R-SSC-5693593 D-loop extension by DNA polymerases IEA Sus scrofa A0A286ZL06 R-SSC-5693608 https://reactome.org/PathwayBrowser/#/R-SSC-5693608 Initial resection of double-strand break ends IEA Sus scrofa A0A286ZL06 R-SSC-5693620 https://reactome.org/PathwayBrowser/#/R-SSC-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Sus scrofa A0A286ZL06 R-SSC-6799332 https://reactome.org/PathwayBrowser/#/R-SSC-6799332 ATR phosphorylates TP53 IEA Sus scrofa A0A286ZL06 R-SSC-9853389 https://reactome.org/PathwayBrowser/#/R-SSC-9853389 FIGNL1 binds RAD51 IEA Sus scrofa A0A286ZL09 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A286ZL11 R-SSC-6805546 https://reactome.org/PathwayBrowser/#/R-SSC-6805546 Keratin type I binds keratin type II IEA Sus scrofa A0A286ZL11 R-SSC-6805573 https://reactome.org/PathwayBrowser/#/R-SSC-6805573 Keratin type I/type II heterodimers form tetramers IEA Sus scrofa A0A286ZL11 R-SSC-6806610 https://reactome.org/PathwayBrowser/#/R-SSC-6806610 Keratin filament formation IEA Sus scrofa A0A286ZL11 R-SSC-6806613 https://reactome.org/PathwayBrowser/#/R-SSC-6806613 Keratin tetramers bind to form unit length filaments IEA Sus scrofa A0A286ZL11 R-SSC-6806629 https://reactome.org/PathwayBrowser/#/R-SSC-6806629 Formation of tonofilament bundles IEA Sus scrofa A0A286ZL11 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A286ZL11 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A286ZL11 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A286ZL11 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A286ZL51 R-SSC-156826 https://reactome.org/PathwayBrowser/#/R-SSC-156826 Dissociation of L13a from the 60s ribosomal subunit IEA Sus scrofa A0A286ZL51 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A286ZL51 R-SSC-6791218 https://reactome.org/PathwayBrowser/#/R-SSC-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Sus scrofa A0A286ZL51 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A286ZL51 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A286ZL51 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A286ZL51 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A286ZL51 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A286ZL51 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A286ZL51 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A286ZL51 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A286ZL52 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A286ZL52 R-SSC-392187 https://reactome.org/PathwayBrowser/#/R-SSC-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Sus scrofa A0A286ZL52 R-SSC-392195 https://reactome.org/PathwayBrowser/#/R-SSC-392195 Gi activation by P2Y purinoceptor 12 IEA Sus scrofa A0A286ZL52 R-SSC-392202 https://reactome.org/PathwayBrowser/#/R-SSC-392202 Dissociation of the P2Y purinoceptor 12:Gi complex IEA Sus scrofa A0A286ZL52 R-SSC-417829 https://reactome.org/PathwayBrowser/#/R-SSC-417829 P2RY12 binds ADP IEA Sus scrofa A0A286ZL52 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A286ZL52 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A286ZL52 R-SSC-9611277 https://reactome.org/PathwayBrowser/#/R-SSC-9611277 P2RY12 binds P2RY12 antagonists IEA Sus scrofa A0A286ZL59 R-SSC-5358475 https://reactome.org/PathwayBrowser/#/R-SSC-5358475 DPH6 ligates ammonium to diphthine-EEF2 IEA Sus scrofa A0A286ZL64 R-SSC-390593 https://reactome.org/PathwayBrowser/#/R-SSC-390593 ATP Hydrolysis By Myosin IEA Sus scrofa A0A286ZL64 R-SSC-390595 https://reactome.org/PathwayBrowser/#/R-SSC-390595 Calcium Binds Troponin-C IEA Sus scrofa A0A286ZL64 R-SSC-390597 https://reactome.org/PathwayBrowser/#/R-SSC-390597 Release Of ADP From Myosin IEA Sus scrofa A0A286ZL64 R-SSC-390598 https://reactome.org/PathwayBrowser/#/R-SSC-390598 Myosin Binds ATP IEA Sus scrofa A0A286ZL65 R-SSC-156826 https://reactome.org/PathwayBrowser/#/R-SSC-156826 Dissociation of L13a from the 60s ribosomal subunit IEA Sus scrofa A0A286ZL65 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A286ZL65 R-SSC-6791218 https://reactome.org/PathwayBrowser/#/R-SSC-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Sus scrofa A0A286ZL65 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A286ZL65 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A286ZL65 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A286ZL65 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A286ZL65 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A286ZL65 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A286ZL65 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A286ZL65 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A286ZL70 R-SSC-6814671 https://reactome.org/PathwayBrowser/#/R-SSC-6814671 Fusion of late-endosome derived vesicles at the TGN IEA Sus scrofa A0A286ZLA2 R-SSC-8949178 https://reactome.org/PathwayBrowser/#/R-SSC-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix IEA Sus scrofa A0A286ZLA2 R-SSC-8953461 https://reactome.org/PathwayBrowser/#/R-SSC-8953461 SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex IEA Sus scrofa A0A286ZLA8 R-SSC-193636 https://reactome.org/PathwayBrowser/#/R-SSC-193636 p75NTR interacts with the NOGO receptor IEA Sus scrofa A0A286ZLA8 R-SSC-193655 https://reactome.org/PathwayBrowser/#/R-SSC-193655 Myelin components can interact with p75NTR:NgR:LINGO1 IEA Sus scrofa A0A286ZLA8 R-SSC-193696 https://reactome.org/PathwayBrowser/#/R-SSC-193696 The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA IEA Sus scrofa A0A286ZLA8 R-SSC-209573 https://reactome.org/PathwayBrowser/#/R-SSC-209573 p75NTR:NgR complex interacts with the axonal inhibitor LINGO1 IEA Sus scrofa A0A286ZLA8 R-SSC-9012761 https://reactome.org/PathwayBrowser/#/R-SSC-9012761 The p75NTR:NgR:MDGI binds RHOA-GDI IEA Sus scrofa A0A286ZLB1 R-SSC-70994 https://reactome.org/PathwayBrowser/#/R-SSC-70994 SDH complex dehydrogenates succinate IEA Sus scrofa A0A286ZLE1 R-SSC-191763 https://reactome.org/PathwayBrowser/#/R-SSC-191763 snRNP:Snurportin complex formation IEA Sus scrofa A0A286ZLE1 R-SSC-191830 https://reactome.org/PathwayBrowser/#/R-SSC-191830 snRNP nuclear import and release IEA Sus scrofa A0A286ZLE7 R-SSC-2872497 https://reactome.org/PathwayBrowser/#/R-SSC-2872497 SLC17A3-2 transports cytosolic urate to extracellular region IEA Sus scrofa A0A286ZLE7 R-SSC-2872498 https://reactome.org/PathwayBrowser/#/R-SSC-2872498 SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol IEA Sus scrofa A0A286ZLF0 R-SSC-6797653 https://reactome.org/PathwayBrowser/#/R-SSC-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Sus scrofa A0A286ZLF6 R-SSC-5623622 https://reactome.org/PathwayBrowser/#/R-SSC-5623622 RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 IEA Sus scrofa A0A286ZLF6 R-SSC-5623632 https://reactome.org/PathwayBrowser/#/R-SSC-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Sus scrofa A0A286ZLF6 R-SSC-5623667 https://reactome.org/PathwayBrowser/#/R-SSC-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Sus scrofa A0A286ZLF6 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa A0A286ZLF6 R-SSC-9013024 https://reactome.org/PathwayBrowser/#/R-SSC-9013024 RHOB binds effectors at the plasma membrane IEA Sus scrofa A0A286ZLF6 R-SSC-9013110 https://reactome.org/PathwayBrowser/#/R-SSC-9013110 RHOC binds effectors at the plasma membrane IEA Sus scrofa A0A286ZLF6 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZLF6 R-SSC-9860785 https://reactome.org/PathwayBrowser/#/R-SSC-9860785 PDPK1 (PDK1) phosphorylates PKN2 on threonine-816 IEA Sus scrofa A0A286ZLF6 R-SSC-9860808 https://reactome.org/PathwayBrowser/#/R-SSC-9860808 p-T816-PKN2 phosphorylates NOS3 (eNOS) on serine-1179 IEA Sus scrofa A0A286ZLF7 R-SSC-2429719 https://reactome.org/PathwayBrowser/#/R-SSC-2429719 MCPH1 sequesters condensin II IEA Sus scrofa A0A286ZLG6 R-SSC-4647594 https://reactome.org/PathwayBrowser/#/R-SSC-4647594 SAHF formation IEA Sus scrofa A0A286ZLH2 R-SSC-5340320 https://reactome.org/PathwayBrowser/#/R-SSC-5340320 GLTP transports GSL from plasma membrane to ER membrane IEA Sus scrofa A0A286ZLH8 R-SSC-156826 https://reactome.org/PathwayBrowser/#/R-SSC-156826 Dissociation of L13a from the 60s ribosomal subunit IEA Sus scrofa A0A286ZLH8 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A286ZLH8 R-SSC-6791218 https://reactome.org/PathwayBrowser/#/R-SSC-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Sus scrofa A0A286ZLH8 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A286ZLH8 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A286ZLH8 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A286ZLH8 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A286ZLH8 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A286ZLH8 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A286ZLH8 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A286ZLH8 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A286ZLI2 R-SSC-1067659 https://reactome.org/PathwayBrowser/#/R-SSC-1067659 Assembly of hexameric IL-6 receptor IEA Sus scrofa A0A286ZLI2 R-SSC-109858 https://reactome.org/PathwayBrowser/#/R-SSC-109858 MAP2K2 binds MAPK1 IEA Sus scrofa A0A286ZLI2 R-SSC-1112510 https://reactome.org/PathwayBrowser/#/R-SSC-1112510 IL6ST is tyrosine phosphorylated IEA Sus scrofa A0A286ZLI2 R-SSC-1112514 https://reactome.org/PathwayBrowser/#/R-SSC-1112514 JAK activation IEA Sus scrofa A0A286ZLI2 R-SSC-1112565 https://reactome.org/PathwayBrowser/#/R-SSC-1112565 Tyrosine phosphorylated IL6ST binds STAT1,STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-1112602 https://reactome.org/PathwayBrowser/#/R-SSC-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Sus scrofa A0A286ZLI2 R-SSC-1112604 https://reactome.org/PathwayBrowser/#/R-SSC-1112604 Phosphorylated STATs are released IEA Sus scrofa A0A286ZLI2 R-SSC-1112690 https://reactome.org/PathwayBrowser/#/R-SSC-1112690 PTPN11 binds CBL IEA Sus scrofa A0A286ZLI2 R-SSC-1112703 https://reactome.org/PathwayBrowser/#/R-SSC-1112703 PTPN11 is phosphorylated IEA Sus scrofa A0A286ZLI2 R-SSC-1112708 https://reactome.org/PathwayBrowser/#/R-SSC-1112708 PTPN11 binds p-Y759-IL6ST IEA Sus scrofa A0A286ZLI2 R-SSC-1112727 https://reactome.org/PathwayBrowser/#/R-SSC-1112727 Serine phosphorylation of STATs IEA Sus scrofa A0A286ZLI2 R-SSC-1112755 https://reactome.org/PathwayBrowser/#/R-SSC-1112755 SOCS3 binds IL6ST IEA Sus scrofa A0A286ZLI2 R-SSC-1169406 https://reactome.org/PathwayBrowser/#/R-SSC-1169406 ISGylation of host proteins IEA Sus scrofa A0A286ZLI2 R-SSC-1295540 https://reactome.org/PathwayBrowser/#/R-SSC-1295540 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 IEA Sus scrofa A0A286ZLI2 R-SSC-1678841 https://reactome.org/PathwayBrowser/#/R-SSC-1678841 Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 IEA Sus scrofa A0A286ZLI2 R-SSC-448427 https://reactome.org/PathwayBrowser/#/R-SSC-448427 Interleukin-27 binds Interleukin-27 receptor IEA Sus scrofa A0A286ZLI2 R-SSC-448480 https://reactome.org/PathwayBrowser/#/R-SSC-448480 IL22 binds IL22RA1:JAK1 receptor complex IEA Sus scrofa A0A286ZLI2 R-SSC-448660 https://reactome.org/PathwayBrowser/#/R-SSC-448660 IL31:IL31RA:JAK1 binds OSMR:JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-448661 https://reactome.org/PathwayBrowser/#/R-SSC-448661 IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-448708 https://reactome.org/PathwayBrowser/#/R-SSC-448708 IL24 binds to IL22RA1:JAK1:IL20RB IEA Sus scrofa A0A286ZLI2 R-SSC-448728 https://reactome.org/PathwayBrowser/#/R-SSC-448728 IL19 binds IL20RA:JAK1:IL20RB IEA Sus scrofa A0A286ZLI2 R-SSC-448744 https://reactome.org/PathwayBrowser/#/R-SSC-448744 IL20RA binds IL20RB IEA Sus scrofa A0A286ZLI2 R-SSC-449803 https://reactome.org/PathwayBrowser/#/R-SSC-449803 IL10 dimer binds IL10RA:JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-449811 https://reactome.org/PathwayBrowser/#/R-SSC-449811 IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 IEA Sus scrofa A0A286ZLI2 R-SSC-449958 https://reactome.org/PathwayBrowser/#/R-SSC-449958 IL7:IL7R:JAK1 binds IL2RG:JAK3 IEA Sus scrofa A0A286ZLI2 R-SSC-449976 https://reactome.org/PathwayBrowser/#/R-SSC-449976 IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) IEA Sus scrofa A0A286ZLI2 R-SSC-449978 https://reactome.org/PathwayBrowser/#/R-SSC-449978 IL7 binds IL7R:JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-450027 https://reactome.org/PathwayBrowser/#/R-SSC-450027 Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta IEA Sus scrofa A0A286ZLI2 R-SSC-450063 https://reactome.org/PathwayBrowser/#/R-SSC-450063 Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit IEA Sus scrofa A0A286ZLI2 R-SSC-451900 https://reactome.org/PathwayBrowser/#/R-SSC-451900 IL2RB binds JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-451942 https://reactome.org/PathwayBrowser/#/R-SSC-451942 Within the IL-2R complex JAK3 phosphorylates JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-452091 https://reactome.org/PathwayBrowser/#/R-SSC-452091 Phosphorylation of IL2RB Y338 enables SHC recruitment IEA Sus scrofa A0A286ZLI2 R-SSC-452097 https://reactome.org/PathwayBrowser/#/R-SSC-452097 Recruited STAT5 is phosphorylated IEA Sus scrofa A0A286ZLI2 R-SSC-452100 https://reactome.org/PathwayBrowser/#/R-SSC-452100 SHC1 bound to IL2 receptor is phosphorylated IEA Sus scrofa A0A286ZLI2 R-SSC-452108 https://reactome.org/PathwayBrowser/#/R-SSC-452108 Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment IEA Sus scrofa A0A286ZLI2 R-SSC-452122 https://reactome.org/PathwayBrowser/#/R-SSC-452122 JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB IEA Sus scrofa A0A286ZLI2 R-SSC-453104 https://reactome.org/PathwayBrowser/#/R-SSC-453104 Phosphorylated SHC1 recruits GRB2:GAB2 IEA Sus scrofa A0A286ZLI2 R-SSC-453111 https://reactome.org/PathwayBrowser/#/R-SSC-453111 Phosphorylated SHC recruits GRB2:SOS1 IEA Sus scrofa A0A286ZLI2 R-SSC-508247 https://reactome.org/PathwayBrowser/#/R-SSC-508247 Gab2 binds the p85 subunit of Class 1A PI3 kinases IEA Sus scrofa A0A286ZLI2 R-SSC-508282 https://reactome.org/PathwayBrowser/#/R-SSC-508282 SYK is a substrate for JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-508292 https://reactome.org/PathwayBrowser/#/R-SSC-508292 SYK binds IL2RB IEA Sus scrofa A0A286ZLI2 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A286ZLI2 R-SSC-5696482 https://reactome.org/PathwayBrowser/#/R-SSC-5696482 CTF1 binds LIFR:JAKs IEA Sus scrofa A0A286ZLI2 R-SSC-6783524 https://reactome.org/PathwayBrowser/#/R-SSC-6783524 OSM,LIF,CTF1 receptor complex binds gp130 IEA Sus scrofa A0A286ZLI2 R-SSC-6783530 https://reactome.org/PathwayBrowser/#/R-SSC-6783530 gp130:JAKs bind CNTFR IEA Sus scrofa A0A286ZLI2 R-SSC-6783552 https://reactome.org/PathwayBrowser/#/R-SSC-6783552 OSM binds LIFR:JAKs,OSMR:JAKs IEA Sus scrofa A0A286ZLI2 R-SSC-6783556 https://reactome.org/PathwayBrowser/#/R-SSC-6783556 LIFR:JAKs bind gp130:JAKs:CNTFR IEA Sus scrofa A0A286ZLI2 R-SSC-6783681 https://reactome.org/PathwayBrowser/#/R-SSC-6783681 LIF binds LIFR IEA Sus scrofa A0A286ZLI2 R-SSC-6784006 https://reactome.org/PathwayBrowser/#/R-SSC-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Sus scrofa A0A286ZLI2 R-SSC-6784189 https://reactome.org/PathwayBrowser/#/R-SSC-6784189 JAKs bind LIFR IEA Sus scrofa A0A286ZLI2 R-SSC-6784204 https://reactome.org/PathwayBrowser/#/R-SSC-6784204 JAKs bind OSMR IEA Sus scrofa A0A286ZLI2 R-SSC-6784319 https://reactome.org/PathwayBrowser/#/R-SSC-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Sus scrofa A0A286ZLI2 R-SSC-6784323 https://reactome.org/PathwayBrowser/#/R-SSC-6784323 IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-6784324 https://reactome.org/PathwayBrowser/#/R-SSC-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Sus scrofa A0A286ZLI2 R-SSC-6784791 https://reactome.org/PathwayBrowser/#/R-SSC-6784791 p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-6785165 https://reactome.org/PathwayBrowser/#/R-SSC-6785165 p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B IEA Sus scrofa A0A286ZLI2 R-SSC-6786050 https://reactome.org/PathwayBrowser/#/R-SSC-6786050 IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated IEA Sus scrofa A0A286ZLI2 R-SSC-6786058 https://reactome.org/PathwayBrowser/#/R-SSC-6786058 JAK1 binds IL4R in IL4-bound IL4R1 IEA Sus scrofa A0A286ZLI2 R-SSC-6786072 https://reactome.org/PathwayBrowser/#/R-SSC-6786072 p-Y705-STAT3,p-Y641-STAT6 dissociate IEA Sus scrofa A0A286ZLI2 R-SSC-6786095 https://reactome.org/PathwayBrowser/#/R-SSC-6786095 JAK1 phosphorylates STAT3,STAT6 IEA Sus scrofa A0A286ZLI2 R-SSC-6786096 https://reactome.org/PathwayBrowser/#/R-SSC-6786096 IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated IEA Sus scrofa A0A286ZLI2 R-SSC-6786110 https://reactome.org/PathwayBrowser/#/R-SSC-6786110 JAK1 binds IL4R in IL13-bound IL13R type II IEA Sus scrofa A0A286ZLI2 R-SSC-6786124 https://reactome.org/PathwayBrowser/#/R-SSC-6786124 STAT3,STAT6 bind p-Y-IL4R IEA Sus scrofa A0A286ZLI2 R-SSC-6788571 https://reactome.org/PathwayBrowser/#/R-SSC-6788571 STAT1,STAT3,STAT6 bind IL13:IL13R type II IEA Sus scrofa A0A286ZLI2 R-SSC-6788582 https://reactome.org/PathwayBrowser/#/R-SSC-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Sus scrofa A0A286ZLI2 R-SSC-6788628 https://reactome.org/PathwayBrowser/#/R-SSC-6788628 p-Y-STATs dissociate IEA Sus scrofa A0A286ZLI2 R-SSC-6809140 https://reactome.org/PathwayBrowser/#/R-SSC-6809140 IL35 binds IL-12RB2:IL6ST receptor IEA Sus scrofa A0A286ZLI2 R-SSC-873918 https://reactome.org/PathwayBrowser/#/R-SSC-873918 Transphosphorylation of JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-873919 https://reactome.org/PathwayBrowser/#/R-SSC-873919 Phosphorylation of JAK2 IEA Sus scrofa A0A286ZLI2 R-SSC-873921 https://reactome.org/PathwayBrowser/#/R-SSC-873921 Binding of STAT1 to p-IFNGR1 IEA Sus scrofa A0A286ZLI2 R-SSC-873922 https://reactome.org/PathwayBrowser/#/R-SSC-873922 Phosphorylation of STAT1 by JAK kinases IEA Sus scrofa A0A286ZLI2 R-SSC-873924 https://reactome.org/PathwayBrowser/#/R-SSC-873924 Phosphorylation of IFNGR1 by JAK kinases IEA Sus scrofa A0A286ZLI2 R-SSC-873926 https://reactome.org/PathwayBrowser/#/R-SSC-873926 IFNG dimer binds IFNGR IEA Sus scrofa A0A286ZLI2 R-SSC-873927 https://reactome.org/PathwayBrowser/#/R-SSC-873927 Release of STAT1 dimer from active receptor unit IEA Sus scrofa A0A286ZLI2 R-SSC-877269 https://reactome.org/PathwayBrowser/#/R-SSC-877269 SOCS-1 and SOCS-3 binds to p-JAK2 IEA Sus scrofa A0A286ZLI2 R-SSC-8854645 https://reactome.org/PathwayBrowser/#/R-SSC-8854645 IL22:IL22RA1:JAK1 binds IL10RB:TYK2 IEA Sus scrofa A0A286ZLI2 R-SSC-8950210 https://reactome.org/PathwayBrowser/#/R-SSC-8950210 Interleukin-27 dissociates from Interleukin-27 receptor IEA Sus scrofa A0A286ZLI2 R-SSC-8950340 https://reactome.org/PathwayBrowser/#/R-SSC-8950340 IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation IEA Sus scrofa A0A286ZLI2 R-SSC-8950405 https://reactome.org/PathwayBrowser/#/R-SSC-8950405 JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated IEA Sus scrofa A0A286ZLI2 R-SSC-8950441 https://reactome.org/PathwayBrowser/#/R-SSC-8950441 p-Y701-STAT1 and p-Y705-STAT3 dissociate from IL27:IL27 receptor IEA Sus scrofa A0A286ZLI2 R-SSC-8950448 https://reactome.org/PathwayBrowser/#/R-SSC-8950448 STAT4 binds to IL12RB2 in Interleukin-12 receptor complex IEA Sus scrofa A0A286ZLI2 R-SSC-8950453 https://reactome.org/PathwayBrowser/#/R-SSC-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Sus scrofa A0A286ZLI2 R-SSC-8950485 https://reactome.org/PathwayBrowser/#/R-SSC-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction IEA Sus scrofa A0A286ZLI2 R-SSC-8950518 https://reactome.org/PathwayBrowser/#/R-SSC-8950518 STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex IEA Sus scrofa A0A286ZLI2 R-SSC-8950537 https://reactome.org/PathwayBrowser/#/R-SSC-8950537 JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated IEA Sus scrofa A0A286ZLI2 R-SSC-8950757 https://reactome.org/PathwayBrowser/#/R-SSC-8950757 IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated IEA Sus scrofa A0A286ZLI2 R-SSC-8952807 https://reactome.org/PathwayBrowser/#/R-SSC-8952807 p-Y693-STAT4 dissociates after IL12:IL12R interaction IEA Sus scrofa A0A286ZLI2 R-SSC-8963734 https://reactome.org/PathwayBrowser/#/R-SSC-8963734 IL9 binds IL9R:JAK1 and IL2RG:JAK3 IEA Sus scrofa A0A286ZLI2 R-SSC-8982162 https://reactome.org/PathwayBrowser/#/R-SSC-8982162 p‑Y705-STAT3 dissociates from IL19:IL20RA:p-JAK1:IL20RB IEA Sus scrofa A0A286ZLI2 R-SSC-8982163 https://reactome.org/PathwayBrowser/#/R-SSC-8982163 IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-8982165 https://reactome.org/PathwayBrowser/#/R-SSC-8982165 IL19:IL20RA:p‑JAK1:IL20RB binds STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-8983003 https://reactome.org/PathwayBrowser/#/R-SSC-8983003 IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 IEA Sus scrofa A0A286ZLI2 R-SSC-8983063 https://reactome.org/PathwayBrowser/#/R-SSC-8983063 JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated IEA Sus scrofa A0A286ZLI2 R-SSC-8983298 https://reactome.org/PathwayBrowser/#/R-SSC-8983298 IL15 binds IL2RB:JAK1 and IL2RG:JAK3 IEA Sus scrofa A0A286ZLI2 R-SSC-8983300 https://reactome.org/PathwayBrowser/#/R-SSC-8983300 IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-8983335 https://reactome.org/PathwayBrowser/#/R-SSC-8983335 IL15:IL15RA:IL2RB:JAK1:IL2RG:JAK3 translocates from the plasma membrane to the endosome IEA Sus scrofa A0A286ZLI2 R-SSC-8983371 https://reactome.org/PathwayBrowser/#/R-SSC-8983371 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 IEA Sus scrofa A0A286ZLI2 R-SSC-8983374 https://reactome.org/PathwayBrowser/#/R-SSC-8983374 p-Y-STAT3 and p-STAT5 dissociates from IL15:IL15RA:IL2RB:p-JAK1:IL2RG:p-JAK3:p-Y-STAT3:p-STAT5 IEA Sus scrofa A0A286ZLI2 R-SSC-8983378 https://reactome.org/PathwayBrowser/#/R-SSC-8983378 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 IEA Sus scrofa A0A286ZLI2 R-SSC-8983384 https://reactome.org/PathwayBrowser/#/R-SSC-8983384 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 IEA Sus scrofa A0A286ZLI2 R-SSC-8983518 https://reactome.org/PathwayBrowser/#/R-SSC-8983518 IL35 binds IL6ST:IL6ST receptor IEA Sus scrofa A0A286ZLI2 R-SSC-8983834 https://reactome.org/PathwayBrowser/#/R-SSC-8983834 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated IEA Sus scrofa A0A286ZLI2 R-SSC-8983835 https://reactome.org/PathwayBrowser/#/R-SSC-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Sus scrofa A0A286ZLI2 R-SSC-8983841 https://reactome.org/PathwayBrowser/#/R-SSC-8983841 STAT1 associates with IL6ST:IL6ST IEA Sus scrofa A0A286ZLI2 R-SSC-8983845 https://reactome.org/PathwayBrowser/#/R-SSC-8983845 p-STAT1 dissociates from IL6ST:IL6ST IEA Sus scrofa A0A286ZLI2 R-SSC-8983983 https://reactome.org/PathwayBrowser/#/R-SSC-8983983 p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor IEA Sus scrofa A0A286ZLI2 R-SSC-8983996 https://reactome.org/PathwayBrowser/#/R-SSC-8983996 STAT1 and STAT4 associate with IL12RB2:IL6ST receptor IEA Sus scrofa A0A286ZLI2 R-SSC-8984001 https://reactome.org/PathwayBrowser/#/R-SSC-8984001 IL35 binds IL27RA:IL12RB2 receptor IEA Sus scrofa A0A286ZLI2 R-SSC-8984012 https://reactome.org/PathwayBrowser/#/R-SSC-8984012 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated IEA Sus scrofa A0A286ZLI2 R-SSC-8984014 https://reactome.org/PathwayBrowser/#/R-SSC-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-8984021 https://reactome.org/PathwayBrowser/#/R-SSC-8984021 STAT1,STAT3 associate with IL27RA:IL12RB2 receptor IEA Sus scrofa A0A286ZLI2 R-SSC-8984023 https://reactome.org/PathwayBrowser/#/R-SSC-8984023 p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor IEA Sus scrofa A0A286ZLI2 R-SSC-8985900 https://reactome.org/PathwayBrowser/#/R-SSC-8985900 p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-8985914 https://reactome.org/PathwayBrowser/#/R-SSC-8985914 IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 IEA Sus scrofa A0A286ZLI2 R-SSC-8985929 https://reactome.org/PathwayBrowser/#/R-SSC-8985929 IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B IEA Sus scrofa A0A286ZLI2 R-SSC-8985973 https://reactome.org/PathwayBrowser/#/R-SSC-8985973 IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 IEA Sus scrofa A0A286ZLI2 R-SSC-8985988 https://reactome.org/PathwayBrowser/#/R-SSC-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Sus scrofa A0A286ZLI2 R-SSC-8986446 https://reactome.org/PathwayBrowser/#/R-SSC-8986446 IL26 binds IL20RA:JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-8986480 https://reactome.org/PathwayBrowser/#/R-SSC-8986480 IL26:IL20RA:JAK1 binds IL10RB:TYK2 IEA Sus scrofa A0A286ZLI2 R-SSC-8986972 https://reactome.org/PathwayBrowser/#/R-SSC-8986972 IL24 binds IL20RA:JAK1:IL20RB IEA Sus scrofa A0A286ZLI2 R-SSC-8986985 https://reactome.org/PathwayBrowser/#/R-SSC-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Sus scrofa A0A286ZLI2 R-SSC-8986994 https://reactome.org/PathwayBrowser/#/R-SSC-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Sus scrofa A0A286ZLI2 R-SSC-8986995 https://reactome.org/PathwayBrowser/#/R-SSC-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Sus scrofa A0A286ZLI2 R-SSC-8987012 https://reactome.org/PathwayBrowser/#/R-SSC-8987012 IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-8987014 https://reactome.org/PathwayBrowser/#/R-SSC-8987014 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-8987015 https://reactome.org/PathwayBrowser/#/R-SSC-8987015 IL20 binds IL20RA:JAK1:IL20RB IEA Sus scrofa A0A286ZLI2 R-SSC-8987033 https://reactome.org/PathwayBrowser/#/R-SSC-8987033 p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 IEA Sus scrofa A0A286ZLI2 R-SSC-8987039 https://reactome.org/PathwayBrowser/#/R-SSC-8987039 JAK1 binds IL20RA IEA Sus scrofa A0A286ZLI2 R-SSC-8987040 https://reactome.org/PathwayBrowser/#/R-SSC-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Sus scrofa A0A286ZLI2 R-SSC-8987042 https://reactome.org/PathwayBrowser/#/R-SSC-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Sus scrofa A0A286ZLI2 R-SSC-8987043 https://reactome.org/PathwayBrowser/#/R-SSC-8987043 IL22RA1 binds JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-8987063 https://reactome.org/PathwayBrowser/#/R-SSC-8987063 IL24:IL22RA1:p-JAK1:IL20RB binds STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-8987070 https://reactome.org/PathwayBrowser/#/R-SSC-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-8987080 https://reactome.org/PathwayBrowser/#/R-SSC-8987080 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-8987084 https://reactome.org/PathwayBrowser/#/R-SSC-8987084 IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-8987096 https://reactome.org/PathwayBrowser/#/R-SSC-8987096 IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-8987097 https://reactome.org/PathwayBrowser/#/R-SSC-8987097 IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-8987104 https://reactome.org/PathwayBrowser/#/R-SSC-8987104 IL20:IL20RA:JAK1:IL20RB:p‑JAK2,p‑JAK3 binds STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-8987105 https://reactome.org/PathwayBrowser/#/R-SSC-8987105 IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-8987120 https://reactome.org/PathwayBrowser/#/R-SSC-8987120 JAK1 binds IFNLR1 IEA Sus scrofa A0A286ZLI2 R-SSC-8987129 https://reactome.org/PathwayBrowser/#/R-SSC-8987129 JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated IEA Sus scrofa A0A286ZLI2 R-SSC-8987132 https://reactome.org/PathwayBrowser/#/R-SSC-8987132 IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11 IEA Sus scrofa A0A286ZLI2 R-SSC-8987141 https://reactome.org/PathwayBrowser/#/R-SSC-8987141 IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-8987150 https://reactome.org/PathwayBrowser/#/R-SSC-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-8987156 https://reactome.org/PathwayBrowser/#/R-SSC-8987156 p-STAT3 dissociates from IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 IEA Sus scrofa A0A286ZLI2 R-SSC-8987161 https://reactome.org/PathwayBrowser/#/R-SSC-8987161 p-STAT3 dissociates from IL24:IL22RA1:p‑JAK1:IL20RB:p‑STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-8987179 https://reactome.org/PathwayBrowser/#/R-SSC-8987179 IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 IEA Sus scrofa A0A286ZLI2 R-SSC-8987202 https://reactome.org/PathwayBrowser/#/R-SSC-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Sus scrofa A0A286ZLI2 R-SSC-8987220 https://reactome.org/PathwayBrowser/#/R-SSC-8987220 IL20:IL20RA:JAK1:IL20RB binds JAK2,JAK3 IEA Sus scrofa A0A286ZLI2 R-SSC-8987230 https://reactome.org/PathwayBrowser/#/R-SSC-8987230 p-STAT1 and p-STAT3 dissociates from IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-8987236 https://reactome.org/PathwayBrowser/#/R-SSC-8987236 p-Y705-STAT3 dissociates from IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-8987255 https://reactome.org/PathwayBrowser/#/R-SSC-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-8987266 https://reactome.org/PathwayBrowser/#/R-SSC-8987266 IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 IEA Sus scrofa A0A286ZLI2 R-SSC-8987270 https://reactome.org/PathwayBrowser/#/R-SSC-8987270 p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3 IEA Sus scrofa A0A286ZLI2 R-SSC-9005980 https://reactome.org/PathwayBrowser/#/R-SSC-9005980 IL21 binds IL21R:JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-9006844 https://reactome.org/PathwayBrowser/#/R-SSC-9006844 IL21:IL21R:JAK1 binds IL2RG:JAK3 IEA Sus scrofa A0A286ZLI2 R-SSC-9006850 https://reactome.org/PathwayBrowser/#/R-SSC-9006850 IL21 receptor JAK phosphorylation IEA Sus scrofa A0A286ZLI2 R-SSC-9006870 https://reactome.org/PathwayBrowser/#/R-SSC-9006870 IL21 receptor STAT phosphorylation IEA Sus scrofa A0A286ZLI2 R-SSC-9006873 https://reactome.org/PathwayBrowser/#/R-SSC-9006873 IL21 receptor STAT binding IEA Sus scrofa A0A286ZLI2 R-SSC-9009227 https://reactome.org/PathwayBrowser/#/R-SSC-9009227 IL20 binds to IL22RA1:JAK1:IL20RB IEA Sus scrofa A0A286ZLI2 R-SSC-9011748 https://reactome.org/PathwayBrowser/#/R-SSC-9011748 IL9R binds JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-9025969 https://reactome.org/PathwayBrowser/#/R-SSC-9025969 IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 binds STAT5 IEA Sus scrofa A0A286ZLI2 R-SSC-909552 https://reactome.org/PathwayBrowser/#/R-SSC-909552 Phosphorylation of STAT1 at Ser727 IEA Sus scrofa A0A286ZLI2 R-SSC-909718 https://reactome.org/PathwayBrowser/#/R-SSC-909718 Formation of p-STAT1 homodimer IEA Sus scrofa A0A286ZLI2 R-SSC-909719 https://reactome.org/PathwayBrowser/#/R-SSC-909719 Recruitment of STAT2 to p-IFNAR1 IEA Sus scrofa A0A286ZLI2 R-SSC-909720 https://reactome.org/PathwayBrowser/#/R-SSC-909720 IFN alpha/beta binds to IFNAR2 IEA Sus scrofa A0A286ZLI2 R-SSC-909722 https://reactome.org/PathwayBrowser/#/R-SSC-909722 Release of p-STAT2:p-STAT1 dimer IEA Sus scrofa A0A286ZLI2 R-SSC-909724 https://reactome.org/PathwayBrowser/#/R-SSC-909724 Recruitment of IFNAR1 IEA Sus scrofa A0A286ZLI2 R-SSC-909729 https://reactome.org/PathwayBrowser/#/R-SSC-909729 Activation of JAK kinases IEA Sus scrofa A0A286ZLI2 R-SSC-909730 https://reactome.org/PathwayBrowser/#/R-SSC-909730 Phosphorylation of INFAR1 by TYK2 IEA Sus scrofa A0A286ZLI2 R-SSC-909732 https://reactome.org/PathwayBrowser/#/R-SSC-909732 Phosphorylation of STAT2 IEA Sus scrofa A0A286ZLI2 R-SSC-912527 https://reactome.org/PathwayBrowser/#/R-SSC-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Sus scrofa A0A286ZLI2 R-SSC-913374 https://reactome.org/PathwayBrowser/#/R-SSC-913374 Phosphorylated SHC1 recruits SHIP IEA Sus scrofa A0A286ZLI2 R-SSC-913424 https://reactome.org/PathwayBrowser/#/R-SSC-913424 The SHC1:SHIP1 complex is stabilized by GRB2 IEA Sus scrofa A0A286ZLI2 R-SSC-919404 https://reactome.org/PathwayBrowser/#/R-SSC-919404 Phosphorylated STAT5 is released IEA Sus scrofa A0A286ZLI2 R-SSC-9674816 https://reactome.org/PathwayBrowser/#/R-SSC-9674816 p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS IEA Sus scrofa A0A286ZLI2 R-SSC-9677579 https://reactome.org/PathwayBrowser/#/R-SSC-9677579 CSF3 dimer (GCSF dimer) binds CSF3R:JAK1:LYN IEA Sus scrofa A0A286ZLI2 R-SSC-9677585 https://reactome.org/PathwayBrowser/#/R-SSC-9677585 CSF3 dimer:CSFR:LYN:JAK1 binds CSFR:LYN:JAK1 IEA Sus scrofa A0A286ZLI2 R-SSC-9678561 https://reactome.org/PathwayBrowser/#/R-SSC-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Sus scrofa A0A286ZLI2 R-SSC-9678935 https://reactome.org/PathwayBrowser/#/R-SSC-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Sus scrofa A0A286ZLI2 R-SSC-9696179 https://reactome.org/PathwayBrowser/#/R-SSC-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Sus scrofa A0A286ZLI2 R-SSC-9707977 https://reactome.org/PathwayBrowser/#/R-SSC-9707977 CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane IEA Sus scrofa A0A286ZLI2 R-SSC-9732738 https://reactome.org/PathwayBrowser/#/R-SSC-9732738 JAK1-mediated phosphorylation of RAF1 IEA Sus scrofa A0A286ZLI2 R-SSC-9732753 https://reactome.org/PathwayBrowser/#/R-SSC-9732753 JAK1-activated RAF1 phosphorylates MAPKs IEA Sus scrofa A0A286ZLI2 R-SSC-9734547 https://reactome.org/PathwayBrowser/#/R-SSC-9734547 JAK2-activated MAPKs phosphorylate YBX1 IEA Sus scrofa A0A286ZLI2 R-SSC-997309 https://reactome.org/PathwayBrowser/#/R-SSC-997309 Dephosphorylation of STAT1 by SHP2 IEA Sus scrofa A0A286ZLI2 R-SSC-997311 https://reactome.org/PathwayBrowser/#/R-SSC-997311 Dephosphorylation of TYK2 by PTP1B IEA Sus scrofa A0A286ZLI2 R-SSC-997314 https://reactome.org/PathwayBrowser/#/R-SSC-997314 Dephosphorylation of JAK1 by SHP1 IEA Sus scrofa A0A286ZLJ1 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A286ZLJ1 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A286ZLJ1 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A286ZLJ1 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A286ZLJ1 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A286ZLJ8 R-SSC-1013012 https://reactome.org/PathwayBrowser/#/R-SSC-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Sus scrofa A0A286ZLJ8 R-SSC-1013013 https://reactome.org/PathwayBrowser/#/R-SSC-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Sus scrofa A0A286ZLJ8 R-SSC-1013020 https://reactome.org/PathwayBrowser/#/R-SSC-1013020 Activation of GIRK/Kir3 Channels IEA Sus scrofa A0A286ZLJ8 R-SSC-112271 https://reactome.org/PathwayBrowser/#/R-SSC-112271 The receptor:G-protein complex dissociates IEA Sus scrofa A0A286ZLJ8 R-SSC-114552 https://reactome.org/PathwayBrowser/#/R-SSC-114552 Thrombin-activated PARs activate G12/13 IEA Sus scrofa A0A286ZLJ8 R-SSC-114558 https://reactome.org/PathwayBrowser/#/R-SSC-114558 Thrombin-activated PARs activate Gq IEA Sus scrofa A0A286ZLJ8 R-SSC-167408 https://reactome.org/PathwayBrowser/#/R-SSC-167408 The high affinity receptor complex binds to G-protein IEA Sus scrofa A0A286ZLJ8 R-SSC-167419 https://reactome.org/PathwayBrowser/#/R-SSC-167419 The receptor:G-protein complex releases GDP IEA Sus scrofa A0A286ZLJ8 R-SSC-167429 https://reactome.org/PathwayBrowser/#/R-SSC-167429 The receptor:G-protein complex binds GTP IEA Sus scrofa A0A286ZLJ8 R-SSC-167433 https://reactome.org/PathwayBrowser/#/R-SSC-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Sus scrofa A0A286ZLJ8 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa A0A286ZLJ8 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A286ZLJ8 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A286ZLJ8 R-SSC-381612 https://reactome.org/PathwayBrowser/#/R-SSC-381612 GLP1R binds GLP1 IEA Sus scrofa A0A286ZLJ8 R-SSC-392187 https://reactome.org/PathwayBrowser/#/R-SSC-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Sus scrofa A0A286ZLJ8 R-SSC-392195 https://reactome.org/PathwayBrowser/#/R-SSC-392195 Gi activation by P2Y purinoceptor 12 IEA Sus scrofa A0A286ZLJ8 R-SSC-392202 https://reactome.org/PathwayBrowser/#/R-SSC-392202 Dissociation of the P2Y purinoceptor 12:Gi complex IEA Sus scrofa A0A286ZLJ8 R-SSC-392295 https://reactome.org/PathwayBrowser/#/R-SSC-392295 Gbeta:gamma recruits PI3K gamma IEA Sus scrofa A0A286ZLJ8 R-SSC-392300 https://reactome.org/PathwayBrowser/#/R-SSC-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Sus scrofa A0A286ZLJ8 R-SSC-392870 https://reactome.org/PathwayBrowser/#/R-SSC-392870 Gs activation by prostacyclin receptor IEA Sus scrofa A0A286ZLJ8 R-SSC-3965444 https://reactome.org/PathwayBrowser/#/R-SSC-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Sus scrofa A0A286ZLJ8 R-SSC-3965447 https://reactome.org/PathwayBrowser/#/R-SSC-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Sus scrofa A0A286ZLJ8 R-SSC-396996 https://reactome.org/PathwayBrowser/#/R-SSC-396996 Thrombin-activated PARs binds G-protein Gq IEA Sus scrofa A0A286ZLJ8 R-SSC-397835 https://reactome.org/PathwayBrowser/#/R-SSC-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Sus scrofa A0A286ZLJ8 R-SSC-397891 https://reactome.org/PathwayBrowser/#/R-SSC-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Sus scrofa A0A286ZLJ8 R-SSC-398040 https://reactome.org/PathwayBrowser/#/R-SSC-398040 Gbeta:gamma activation of PLC beta IEA Sus scrofa A0A286ZLJ8 R-SSC-398193 https://reactome.org/PathwayBrowser/#/R-SSC-398193 PLC beta-mediated PIP2 hydrolysis IEA Sus scrofa A0A286ZLJ8 R-SSC-400037 https://reactome.org/PathwayBrowser/#/R-SSC-400037 Gi,Go Heterotrimeric G-protein complex dissociates IEA Sus scrofa A0A286ZLJ8 R-SSC-400092 https://reactome.org/PathwayBrowser/#/R-SSC-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Sus scrofa A0A286ZLJ8 R-SSC-400097 https://reactome.org/PathwayBrowser/#/R-SSC-400097 G-beta:G-gamma inhibits Adenylate cyclase IEA Sus scrofa A0A286ZLJ8 R-SSC-418576 https://reactome.org/PathwayBrowser/#/R-SSC-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Sus scrofa A0A286ZLJ8 R-SSC-420883 https://reactome.org/PathwayBrowser/#/R-SSC-420883 Opsins act as GEFs for G alpha-t IEA Sus scrofa A0A286ZLJ8 R-SSC-428749 https://reactome.org/PathwayBrowser/#/R-SSC-428749 Activated TP receptor binds G-proten Gq IEA Sus scrofa A0A286ZLJ8 R-SSC-428750 https://reactome.org/PathwayBrowser/#/R-SSC-428750 Gq activation by TP receptor IEA Sus scrofa A0A286ZLJ8 R-SSC-428752 https://reactome.org/PathwayBrowser/#/R-SSC-428752 Dissociation of the TP:Gq complex IEA Sus scrofa A0A286ZLJ8 R-SSC-428909 https://reactome.org/PathwayBrowser/#/R-SSC-428909 Activated TP receptor binds G-protein G13 IEA Sus scrofa A0A286ZLJ8 R-SSC-428917 https://reactome.org/PathwayBrowser/#/R-SSC-428917 G13 activation by TP receptor IEA Sus scrofa A0A286ZLJ8 R-SSC-428918 https://reactome.org/PathwayBrowser/#/R-SSC-428918 Dissociation of the TP:G13 complex IEA Sus scrofa A0A286ZLJ8 R-SSC-432195 https://reactome.org/PathwayBrowser/#/R-SSC-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Sus scrofa A0A286ZLJ8 R-SSC-500717 https://reactome.org/PathwayBrowser/#/R-SSC-500717 Activation of GRIK3 homomer IEA Sus scrofa A0A286ZLJ8 R-SSC-6814418 https://reactome.org/PathwayBrowser/#/R-SSC-6814418 PDCL promotes formation of G-beta:G-gamma heterodimers IEA Sus scrofa A0A286ZLJ8 R-SSC-749446 https://reactome.org/PathwayBrowser/#/R-SSC-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Sus scrofa A0A286ZLJ8 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A286ZLJ8 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A286ZLJ8 R-SSC-749453 https://reactome.org/PathwayBrowser/#/R-SSC-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Sus scrofa A0A286ZLJ8 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A286ZLJ8 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A286ZLJ8 R-SSC-750988 https://reactome.org/PathwayBrowser/#/R-SSC-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Sus scrofa A0A286ZLJ8 R-SSC-750993 https://reactome.org/PathwayBrowser/#/R-SSC-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Sus scrofa A0A286ZLJ8 R-SSC-751001 https://reactome.org/PathwayBrowser/#/R-SSC-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Sus scrofa A0A286ZLJ8 R-SSC-751019 https://reactome.org/PathwayBrowser/#/R-SSC-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Sus scrofa A0A286ZLJ8 R-SSC-751024 https://reactome.org/PathwayBrowser/#/R-SSC-751024 The Ligand:GPCR:Gz complex dissociates IEA Sus scrofa A0A286ZLJ8 R-SSC-751027 https://reactome.org/PathwayBrowser/#/R-SSC-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Sus scrofa A0A286ZLJ8 R-SSC-751029 https://reactome.org/PathwayBrowser/#/R-SSC-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Sus scrofa A0A286ZLJ8 R-SSC-751039 https://reactome.org/PathwayBrowser/#/R-SSC-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Sus scrofa A0A286ZLJ8 R-SSC-8850560 https://reactome.org/PathwayBrowser/#/R-SSC-8850560 G-protein alpha releases G-protein heterotrimer from PDCL IEA Sus scrofa A0A286ZLJ8 R-SSC-8964241 https://reactome.org/PathwayBrowser/#/R-SSC-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Sus scrofa A0A286ZLJ8 R-SSC-8964271 https://reactome.org/PathwayBrowser/#/R-SSC-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Sus scrofa A0A286ZLJ8 R-SSC-8964317 https://reactome.org/PathwayBrowser/#/R-SSC-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Sus scrofa A0A286ZLJ8 R-SSC-8964599 https://reactome.org/PathwayBrowser/#/R-SSC-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Sus scrofa A0A286ZLJ8 R-SSC-8964604 https://reactome.org/PathwayBrowser/#/R-SSC-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Sus scrofa A0A286ZLJ8 R-SSC-8964605 https://reactome.org/PathwayBrowser/#/R-SSC-8964605 PAK1:ARHGEF6 complex binds G-protein beta-gamma complex IEA Sus scrofa A0A286ZLJ8 R-SSC-8964614 https://reactome.org/PathwayBrowser/#/R-SSC-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Sus scrofa A0A286ZLJ8 R-SSC-8964634 https://reactome.org/PathwayBrowser/#/R-SSC-8964634 CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex IEA Sus scrofa A0A286ZLJ8 R-SSC-8982637 https://reactome.org/PathwayBrowser/#/R-SSC-8982637 Opsins binds G alpha-t IEA Sus scrofa A0A286ZLJ8 R-SSC-8982640 https://reactome.org/PathwayBrowser/#/R-SSC-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Sus scrofa A0A286ZLJ8 R-SSC-9021596 https://reactome.org/PathwayBrowser/#/R-SSC-9021596 Membrane estrogen receptors bind SRC IEA Sus scrofa A0A286ZLJ8 R-SSC-9021600 https://reactome.org/PathwayBrowser/#/R-SSC-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Sus scrofa A0A286ZLJ8 R-SSC-9021601 https://reactome.org/PathwayBrowser/#/R-SSC-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Sus scrofa A0A286ZLJ8 R-SSC-9036301 https://reactome.org/PathwayBrowser/#/R-SSC-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Sus scrofa A0A286ZLJ8 R-SSC-9036307 https://reactome.org/PathwayBrowser/#/R-SSC-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Sus scrofa A0A286ZLJ8 R-SSC-9728664 https://reactome.org/PathwayBrowser/#/R-SSC-9728664 GLP1R binds GLP1R agonists IEA Sus scrofa A0A286ZLJ8 R-SSC-9861324 https://reactome.org/PathwayBrowser/#/R-SSC-9861324 ADM:CALCRL:RAMP2:G-alpha(s):GDP:G-beta:G-gamma exchanges GDP for GTP IEA Sus scrofa A0A286ZLM1 R-SSC-914010 https://reactome.org/PathwayBrowser/#/R-SSC-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Sus scrofa A0A286ZLN3 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa A0A286ZLN3 R-SSC-1981104 https://reactome.org/PathwayBrowser/#/R-SSC-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Sus scrofa A0A286ZLN3 R-SSC-1981120 https://reactome.org/PathwayBrowser/#/R-SSC-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Sus scrofa A0A286ZLN3 R-SSC-1981128 https://reactome.org/PathwayBrowser/#/R-SSC-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Sus scrofa A0A286ZLN3 R-SSC-1981157 https://reactome.org/PathwayBrowser/#/R-SSC-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Sus scrofa A0A286ZLN3 R-SSC-2002460 https://reactome.org/PathwayBrowser/#/R-SSC-2002460 P4HB binds Collagen chains IEA Sus scrofa A0A286ZLN3 R-SSC-2152276 https://reactome.org/PathwayBrowser/#/R-SSC-2152276 Secretion of transmembrane collagens IEA Sus scrofa A0A286ZLN3 R-SSC-2471842 https://reactome.org/PathwayBrowser/#/R-SSC-2471842 Collagen type XXV ectomain shedding IEA Sus scrofa A0A286ZLN3 R-SSC-8944250 https://reactome.org/PathwayBrowser/#/R-SSC-8944250 Association of procollagen type XXV IEA Sus scrofa A0A286ZLN3 R-SSC-8948219 https://reactome.org/PathwayBrowser/#/R-SSC-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A286ZLN3 R-SSC-8948222 https://reactome.org/PathwayBrowser/#/R-SSC-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A286ZLN3 R-SSC-8948224 https://reactome.org/PathwayBrowser/#/R-SSC-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A286ZLN3 R-SSC-8948228 https://reactome.org/PathwayBrowser/#/R-SSC-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A286ZLN3 R-SSC-8948231 https://reactome.org/PathwayBrowser/#/R-SSC-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A286ZLN3 R-SSC-8948232 https://reactome.org/PathwayBrowser/#/R-SSC-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Sus scrofa A0A286ZLN3 R-SSC-8948234 https://reactome.org/PathwayBrowser/#/R-SSC-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Sus scrofa A0A286ZLN6 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A286ZLN6 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A286ZLN6 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A286ZLN6 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A286ZLN6 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A286ZLN6 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A286ZLN6 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A286ZLN6 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A286ZLN6 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A286ZLN6 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZLN6 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A286ZLN6 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A286ZLN6 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A286ZLN6 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A286ZLN6 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A286ZLN6 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A286ZLN6 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A286ZLN6 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A286ZLN6 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A286ZLN6 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A286ZLN6 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A286ZLN6 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A286ZLN6 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A286ZLN6 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A286ZLN6 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A286ZLN6 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A286ZLN6 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A286ZLN6 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A286ZLN6 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A286ZLN6 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A286ZLN6 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A286ZLN6 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A286ZLN6 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A286ZLN6 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A286ZLN6 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A286ZLN6 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A286ZLN6 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A286ZLN6 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A286ZLN6 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A286ZLN6 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A286ZLN6 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A286ZLN6 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A286ZLN6 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A286ZLN6 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A286ZLN6 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A286ZLN6 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A286ZLN6 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A286ZLP7 R-SSC-9907965 https://reactome.org/PathwayBrowser/#/R-SSC-9907965 PSMD9 binds PSMC3:PSMC6 IEA Sus scrofa A0A286ZLP7 R-SSC-9907980 https://reactome.org/PathwayBrowser/#/R-SSC-9907980 Formation of the 19S regulatory particle base precursor IEA Sus scrofa A0A286ZLS4 R-SSC-8953917 https://reactome.org/PathwayBrowser/#/R-SSC-8953917 PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 IEA Sus scrofa A0A286ZLS4 R-SSC-8953946 https://reactome.org/PathwayBrowser/#/R-SSC-8953946 PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 IEA Sus scrofa A0A286ZLS4 R-SSC-9033235 https://reactome.org/PathwayBrowser/#/R-SSC-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A286ZLS4 R-SSC-9033236 https://reactome.org/PathwayBrowser/#/R-SSC-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Sus scrofa A0A286ZLS4 R-SSC-9033485 https://reactome.org/PathwayBrowser/#/R-SSC-9033485 PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 IEA Sus scrofa A0A286ZLS4 R-SSC-9033499 https://reactome.org/PathwayBrowser/#/R-SSC-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Sus scrofa A0A286ZLS4 R-SSC-9033514 https://reactome.org/PathwayBrowser/#/R-SSC-9033514 Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A286ZLS4 R-SSC-9033516 https://reactome.org/PathwayBrowser/#/R-SSC-9033516 PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Sus scrofa A0A286ZLS4 R-SSC-9033527 https://reactome.org/PathwayBrowser/#/R-SSC-9033527 PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 IEA Sus scrofa A0A286ZLS4 R-SSC-9033533 https://reactome.org/PathwayBrowser/#/R-SSC-9033533 PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Sus scrofa A0A286ZLS4 R-SSC-9603775 https://reactome.org/PathwayBrowser/#/R-SSC-9603775 PEX3:PEX19:class I PMP dissociates IEA Sus scrofa A0A286ZLS4 R-SSC-9603784 https://reactome.org/PathwayBrowser/#/R-SSC-9603784 PEX19:class I PMP binds PEX3 IEA Sus scrofa A0A286ZLS4 R-SSC-9603804 https://reactome.org/PathwayBrowser/#/R-SSC-9603804 PEX19 binds class I peroxisomal membrane proteins IEA Sus scrofa A0A286ZLS5 R-SSC-193684 https://reactome.org/PathwayBrowser/#/R-SSC-193684 p62 recruits an atypical PKC IEA Sus scrofa A0A286ZLS5 R-SSC-419981 https://reactome.org/PathwayBrowser/#/R-SSC-419981 Recruitment of PAR-3:PAR-6:aPKC complex to tight junctions IEA Sus scrofa A0A286ZLS5 R-SSC-9021357 https://reactome.org/PathwayBrowser/#/R-SSC-9021357 PRKCI phosphorylates ELF3 IEA Sus scrofa A0A286ZLS5 R-SSC-9796053 https://reactome.org/PathwayBrowser/#/R-SSC-9796053 PRKCI phosphorylates NFE2L2 IEA Sus scrofa A0A286ZLU1 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZLU1 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A286ZLU1 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A286ZLU1 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A286ZLU1 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZLU1 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZLU1 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A286ZLU1 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZLU1 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A286ZLU2 R-SSC-71218 https://reactome.org/PathwayBrowser/#/R-SSC-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Sus scrofa A0A286ZLZ9 R-SSC-176298 https://reactome.org/PathwayBrowser/#/R-SSC-176298 Activation of claspin IEA Sus scrofa A0A286ZLZ9 R-SSC-176318 https://reactome.org/PathwayBrowser/#/R-SSC-176318 Loading of claspin onto DNA during replication origin firing IEA Sus scrofa A0A286ZLZ9 R-SSC-351936 https://reactome.org/PathwayBrowser/#/R-SSC-351936 Caspase-mediated cleavage of claspin IEA Sus scrofa A0A286ZLZ9 R-SSC-5684882 https://reactome.org/PathwayBrowser/#/R-SSC-5684882 CHEK1 is recruited to resected DNA DSBs IEA Sus scrofa A0A286ZLZ9 R-SSC-5684887 https://reactome.org/PathwayBrowser/#/R-SSC-5684887 Activation of CHEK1 at resected DNA DSBs IEA Sus scrofa A0A286ZLZ9 R-SSC-5696914 https://reactome.org/PathwayBrowser/#/R-SSC-5696914 USP28 deubiquitinates CLSPN and MYC IEA Sus scrofa A0A286ZM00 R-SSC-3928578 https://reactome.org/PathwayBrowser/#/R-SSC-3928578 EPH receptors autophosphorylate IEA Sus scrofa A0A286ZM00 R-SSC-3928591 https://reactome.org/PathwayBrowser/#/R-SSC-3928591 EPH:EFN tetramers oligomerise IEA Sus scrofa A0A286ZM00 R-SSC-3928597 https://reactome.org/PathwayBrowser/#/R-SSC-3928597 EPH:EFN dimers tetramerise IEA Sus scrofa A0A286ZM00 R-SSC-3928604 https://reactome.org/PathwayBrowser/#/R-SSC-3928604 SFKs phosphorylate VAV2,3 IEA Sus scrofa A0A286ZM00 R-SSC-3928607 https://reactome.org/PathwayBrowser/#/R-SSC-3928607 p-EPHs bind VAV2,3 IEA Sus scrofa A0A286ZM00 R-SSC-3928628 https://reactome.org/PathwayBrowser/#/R-SSC-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa A0A286ZM00 R-SSC-3928642 https://reactome.org/PathwayBrowser/#/R-SSC-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa A0A286ZM00 R-SSC-3928646 https://reactome.org/PathwayBrowser/#/R-SSC-3928646 EPHAs bind EFNAs IEA Sus scrofa A0A286ZM00 R-SSC-3928651 https://reactome.org/PathwayBrowser/#/R-SSC-3928651 NGEF exchanges GTP for GDP on RHOA IEA Sus scrofa A0A286ZM00 R-SSC-4093327 https://reactome.org/PathwayBrowser/#/R-SSC-4093327 EPHA binds TIAM1 IEA Sus scrofa A0A286ZM09 R-SSC-5610766 https://reactome.org/PathwayBrowser/#/R-SSC-5610766 The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base IEA Sus scrofa A0A286ZM09 R-SSC-5610767 https://reactome.org/PathwayBrowser/#/R-SSC-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Sus scrofa A0A286ZM09 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A286ZM09 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A286ZM09 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A286ZM16 R-SSC-9645598 https://reactome.org/PathwayBrowser/#/R-SSC-9645598 RRAGC,D hydrolyzes GTP IEA Sus scrofa A0A286ZM17 R-SSC-5658231 https://reactome.org/PathwayBrowser/#/R-SSC-5658231 RAS GAPs stimulate RAS GTPase activity IEA Sus scrofa A0A286ZM17 R-SSC-5658435 https://reactome.org/PathwayBrowser/#/R-SSC-5658435 RAS GAPs bind RAS:GTP IEA Sus scrofa A0A286ZM17 R-SSC-9696268 https://reactome.org/PathwayBrowser/#/R-SSC-9696268 RND3 binds effectors IEA Sus scrofa A0A286ZM17 R-SSC-9696271 https://reactome.org/PathwayBrowser/#/R-SSC-9696271 RND1 binds effectors IEA Sus scrofa A0A286ZM32 R-SSC-5173005 https://reactome.org/PathwayBrowser/#/R-SSC-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Sus scrofa A0A286ZM32 R-SSC-5173192 https://reactome.org/PathwayBrowser/#/R-SSC-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Sus scrofa A0A286ZM41 R-SSC-9603775 https://reactome.org/PathwayBrowser/#/R-SSC-9603775 PEX3:PEX19:class I PMP dissociates IEA Sus scrofa A0A286ZM41 R-SSC-9603784 https://reactome.org/PathwayBrowser/#/R-SSC-9603784 PEX19:class I PMP binds PEX3 IEA Sus scrofa A0A286ZM41 R-SSC-9603804 https://reactome.org/PathwayBrowser/#/R-SSC-9603804 PEX19 binds class I peroxisomal membrane proteins IEA Sus scrofa A0A286ZM64 R-SSC-419003 https://reactome.org/PathwayBrowser/#/R-SSC-419003 Interaction of Nectins with Afadin IEA Sus scrofa A0A286ZM73 R-SSC-6800426 https://reactome.org/PathwayBrowser/#/R-SSC-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Sus scrofa A0A286ZM79 R-SSC-1482604 https://reactome.org/PathwayBrowser/#/R-SSC-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Sus scrofa A0A286ZM79 R-SSC-1482656 https://reactome.org/PathwayBrowser/#/R-SSC-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Sus scrofa A0A286ZM79 R-SSC-1482900 https://reactome.org/PathwayBrowser/#/R-SSC-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Sus scrofa A0A286ZM79 R-SSC-1602368 https://reactome.org/PathwayBrowser/#/R-SSC-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Sus scrofa A0A286ZM79 R-SSC-1602374 https://reactome.org/PathwayBrowser/#/R-SSC-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Sus scrofa A0A286ZM79 R-SSC-1602377 https://reactome.org/PathwayBrowser/#/R-SSC-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Sus scrofa A0A286ZM79 R-SSC-1602398 https://reactome.org/PathwayBrowser/#/R-SSC-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Sus scrofa A0A286ZM79 R-SSC-1602417 https://reactome.org/PathwayBrowser/#/R-SSC-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Sus scrofa A0A286ZM79 R-SSC-1602446 https://reactome.org/PathwayBrowser/#/R-SSC-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Sus scrofa A0A286ZM82 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A286ZM83 R-SSC-2730664 https://reactome.org/PathwayBrowser/#/R-SSC-2730664 UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol IEA Sus scrofa A0A286ZM90 R-SSC-5649764 https://reactome.org/PathwayBrowser/#/R-SSC-5649764 DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) IEA Sus scrofa A0A286ZM90 R-SSC-5649799 https://reactome.org/PathwayBrowser/#/R-SSC-5649799 DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) IEA Sus scrofa A0A286ZM90 R-SSC-5649801 https://reactome.org/PathwayBrowser/#/R-SSC-5649801 DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) IEA Sus scrofa A0A286ZM93 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A286ZM93 R-SSC-9842833 https://reactome.org/PathwayBrowser/#/R-SSC-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Sus scrofa A0A286ZM99 R-SSC-8850831 https://reactome.org/PathwayBrowser/#/R-SSC-8850831 KLK5 cleaves and activates KLK8 IEA Sus scrofa A0A286ZMB2 R-SSC-6798745 https://reactome.org/PathwayBrowser/#/R-SSC-6798745 Exocytosis of tertiary granule lumen proteins IEA Sus scrofa A0A286ZMB2 R-SSC-6798749 https://reactome.org/PathwayBrowser/#/R-SSC-6798749 Exocytosis of specific granule lumen proteins IEA Sus scrofa A0A286ZMB2 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A286ZMD0 R-SSC-5682388 https://reactome.org/PathwayBrowser/#/R-SSC-5682388 Autophagosome maturation IEA Sus scrofa A0A286ZME9 R-SSC-1362261 https://reactome.org/PathwayBrowser/#/R-SSC-1362261 p130 (RBL2) associates with MuvB to form DREAM complex IEA Sus scrofa A0A286ZME9 R-SSC-1362270 https://reactome.org/PathwayBrowser/#/R-SSC-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Sus scrofa A0A286ZMF4 R-SSC-210426 https://reactome.org/PathwayBrowser/#/R-SSC-210426 Glutamate synaptic vesicle docking and priming IEA Sus scrofa A0A286ZMF4 R-SSC-210430 https://reactome.org/PathwayBrowser/#/R-SSC-210430 Release of L-Glutamate at the synapse IEA Sus scrofa A0A286ZMF4 R-SSC-372505 https://reactome.org/PathwayBrowser/#/R-SSC-372505 Acetylcholine synaptic vesicle docking and priming IEA Sus scrofa A0A286ZMF4 R-SSC-372529 https://reactome.org/PathwayBrowser/#/R-SSC-372529 Release of acetylcholine at the synapse IEA Sus scrofa A0A286ZMF4 R-SSC-374899 https://reactome.org/PathwayBrowser/#/R-SSC-374899 Release of noradrenaline at the synapse IEA Sus scrofa A0A286ZMF4 R-SSC-374922 https://reactome.org/PathwayBrowser/#/R-SSC-374922 Noradrenalin synaptic vesicle docking and priming IEA Sus scrofa A0A286ZMF4 R-SSC-380574 https://reactome.org/PathwayBrowser/#/R-SSC-380574 Dopamine synaptic vesicle docking and priming IEA Sus scrofa A0A286ZMF4 R-SSC-380869 https://reactome.org/PathwayBrowser/#/R-SSC-380869 Release of docked dopamine loaded synaptic vesicle IEA Sus scrofa A0A286ZMF4 R-SSC-380901 https://reactome.org/PathwayBrowser/#/R-SSC-380901 Release of docked serotonin loaded synaptic vesicle IEA Sus scrofa A0A286ZMF4 R-SSC-380905 https://reactome.org/PathwayBrowser/#/R-SSC-380905 Serotonin loaded synaptic vesicle docking and priming IEA Sus scrofa A0A286ZMF4 R-SSC-388824 https://reactome.org/PathwayBrowser/#/R-SSC-388824 PTPRF, PTPRS, PTPRD bind Liprins IEA Sus scrofa A0A286ZMF6 R-SSC-114263 https://reactome.org/PathwayBrowser/#/R-SSC-114263 Oligomerization of BAK at the mitochondrial membrane IEA Sus scrofa A0A286ZMF6 R-SSC-114284 https://reactome.org/PathwayBrowser/#/R-SSC-114284 Release of Cytochrome c from mitochondria IEA Sus scrofa A0A286ZMF6 R-SSC-114307 https://reactome.org/PathwayBrowser/#/R-SSC-114307 Release of SMAC (DIABLO) from mitochondria IEA Sus scrofa A0A286ZMF6 R-SSC-139895 https://reactome.org/PathwayBrowser/#/R-SSC-139895 tBID activates BAK protein IEA Sus scrofa A0A286ZMF6 R-SSC-168848 https://reactome.org/PathwayBrowser/#/R-SSC-168848 tBID binds to inactive BAK protein IEA Sus scrofa A0A286ZMI4 R-SSC-444773 https://reactome.org/PathwayBrowser/#/R-SSC-444773 EGF-TM7 receptors bind chondroitin sulphate IEA Sus scrofa A0A286ZMI8 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A286ZML4 R-SSC-1482961 https://reactome.org/PathwayBrowser/#/R-SSC-1482961 CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane IEA Sus scrofa A0A286ZML4 R-SSC-1482962 https://reactome.org/PathwayBrowser/#/R-SSC-1482962 CDP-ETA and DAG are converted to PE by CEPT1/EPT1 IEA Sus scrofa A0A286ZMM6 R-SSC-1170539 https://reactome.org/PathwayBrowser/#/R-SSC-1170539 Prolactin receptor is internalized IEA Sus scrofa A0A286ZMM6 R-SSC-1363328 https://reactome.org/PathwayBrowser/#/R-SSC-1363328 Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex IEA Sus scrofa A0A286ZMM6 R-SSC-1363331 https://reactome.org/PathwayBrowser/#/R-SSC-1363331 Ubiquitination of p130 (RBL2) by SCF (Skp2) IEA Sus scrofa A0A286ZMM6 R-SSC-1370500 https://reactome.org/PathwayBrowser/#/R-SSC-1370500 PRLR binds SCF beta-TrCP complex IEA Sus scrofa A0A286ZMM6 R-SSC-174159 https://reactome.org/PathwayBrowser/#/R-SSC-174159 Ubiquitination of Emi1 by SCF-beta-TrCP IEA Sus scrofa A0A286ZMM6 R-SSC-187545 https://reactome.org/PathwayBrowser/#/R-SSC-187545 Association of Cks1 with SCF(Skp2) complex IEA Sus scrofa A0A286ZMM6 R-SSC-187552 https://reactome.org/PathwayBrowser/#/R-SSC-187552 Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex IEA Sus scrofa A0A286ZMM6 R-SSC-187574 https://reactome.org/PathwayBrowser/#/R-SSC-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Sus scrofa A0A286ZMM6 R-SSC-187575 https://reactome.org/PathwayBrowser/#/R-SSC-187575 Ubiquitination of phospho-p27/p21 IEA Sus scrofa A0A286ZMM6 R-SSC-209063 https://reactome.org/PathwayBrowser/#/R-SSC-209063 Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex IEA Sus scrofa A0A286ZMM6 R-SSC-209125 https://reactome.org/PathwayBrowser/#/R-SSC-209125 SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex IEA Sus scrofa A0A286ZMM6 R-SSC-2130279 https://reactome.org/PathwayBrowser/#/R-SSC-2130279 Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex IEA Sus scrofa A0A286ZMM6 R-SSC-2130282 https://reactome.org/PathwayBrowser/#/R-SSC-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Sus scrofa A0A286ZMM6 R-SSC-2130286 https://reactome.org/PathwayBrowser/#/R-SSC-2130286 Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) IEA Sus scrofa A0A286ZMM6 R-SSC-5610742 https://reactome.org/PathwayBrowser/#/R-SSC-5610742 SCF(beta-TrCP) ubiquitinates p-GLI1 IEA Sus scrofa A0A286ZMM6 R-SSC-5610746 https://reactome.org/PathwayBrowser/#/R-SSC-5610746 SCF(beta-TrCP) ubiquitinates p-GLI3 IEA Sus scrofa A0A286ZMM6 R-SSC-5691108 https://reactome.org/PathwayBrowser/#/R-SSC-5691108 SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 IEA Sus scrofa A0A286ZMM6 R-SSC-5691131 https://reactome.org/PathwayBrowser/#/R-SSC-5691131 CANDI binds CUL1 IEA Sus scrofa A0A286ZMM6 R-SSC-5691167 https://reactome.org/PathwayBrowser/#/R-SSC-5691167 CUL1, SKP1, FBXL5 bind IEA Sus scrofa A0A286ZMM6 R-SSC-5691176 https://reactome.org/PathwayBrowser/#/R-SSC-5691176 NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) IEA Sus scrofa A0A286ZMM6 R-SSC-68946 https://reactome.org/PathwayBrowser/#/R-SSC-68946 Phosphorylated Orc1 is ubiquitinated while still associated with chromatin IEA Sus scrofa A0A286ZMM6 R-SSC-8853496 https://reactome.org/PathwayBrowser/#/R-SSC-8853496 SCF:FBXL7 binds AURKA IEA Sus scrofa A0A286ZMM6 R-SSC-8854041 https://reactome.org/PathwayBrowser/#/R-SSC-8854041 SCF-FBXL7 ubiquitinates AURKA IEA Sus scrofa A0A286ZMM6 R-SSC-8854044 https://reactome.org/PathwayBrowser/#/R-SSC-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Sus scrofa A0A286ZMM6 R-SSC-8854051 https://reactome.org/PathwayBrowser/#/R-SSC-8854051 SCF-FBXL18 ubiquitinates FBXL7 IEA Sus scrofa A0A286ZMM6 R-SSC-8854052 https://reactome.org/PathwayBrowser/#/R-SSC-8854052 Formation of the SCF-FBXL7 complex IEA Sus scrofa A0A286ZMM6 R-SSC-8939688 https://reactome.org/PathwayBrowser/#/R-SSC-8939688 SCF(SKP2) complex binds RUNX2 IEA Sus scrofa A0A286ZMM6 R-SSC-8939706 https://reactome.org/PathwayBrowser/#/R-SSC-8939706 SCF(SKP2) polyubiquitinates RUNX2 IEA Sus scrofa A0A286ZMM6 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZMM6 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A286ZMM6 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A286ZMM6 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A286ZMM6 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZMM6 R-SSC-9708517 https://reactome.org/PathwayBrowser/#/R-SSC-9708517 FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2)) IEA Sus scrofa A0A286ZMM6 R-SSC-9708525 https://reactome.org/PathwayBrowser/#/R-SSC-9708525 BACH1:FBXL17 binds SCF(SKP2) complex IEA Sus scrofa A0A286ZMM6 R-SSC-9762091 https://reactome.org/PathwayBrowser/#/R-SSC-9762091 NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 IEA Sus scrofa A0A286ZMM6 R-SSC-9762093 https://reactome.org/PathwayBrowser/#/R-SSC-9762093 BTRC binds p-S344, 347 NFE2L2 IEA Sus scrofa A0A286ZMM6 R-SSC-9762096 https://reactome.org/PathwayBrowser/#/R-SSC-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Sus scrofa A0A286ZMM6 R-SSC-976991 https://reactome.org/PathwayBrowser/#/R-SSC-976991 Prolactin receptor ligands bind the prolactin receptor IEA Sus scrofa A0A286ZMM6 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZMM6 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A286ZMM6 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZMM6 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A286ZMN5 R-SSC-1855182 https://reactome.org/PathwayBrowser/#/R-SSC-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Sus scrofa A0A286ZMN5 R-SSC-1855216 https://reactome.org/PathwayBrowser/#/R-SSC-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Sus scrofa A0A286ZMP2 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A286ZMP2 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A286ZMP2 R-SSC-8854255 https://reactome.org/PathwayBrowser/#/R-SSC-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Sus scrofa A0A286ZMP2 R-SSC-8854329 https://reactome.org/PathwayBrowser/#/R-SSC-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Sus scrofa A0A286ZMP2 R-SSC-8877451 https://reactome.org/PathwayBrowser/#/R-SSC-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Sus scrofa A0A286ZMP2 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZMP2 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZMP2 R-SSC-9014294 https://reactome.org/PathwayBrowser/#/R-SSC-9014294 RAC2 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZMP2 R-SSC-9014449 https://reactome.org/PathwayBrowser/#/R-SSC-9014449 RHOG binds effectors at the plasma membrane IEA Sus scrofa A0A286ZMP2 R-SSC-9018746 https://reactome.org/PathwayBrowser/#/R-SSC-9018746 RHOQ binds effectors at the plasma membrane IEA Sus scrofa A0A286ZMP2 R-SSC-9018758 https://reactome.org/PathwayBrowser/#/R-SSC-9018758 RHOH binds effectors at the plasma membrane IEA Sus scrofa A0A286ZMP2 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZMP2 R-SSC-9693125 https://reactome.org/PathwayBrowser/#/R-SSC-9693125 RHOF binds effectors at the plasma membrane IEA Sus scrofa A0A286ZMP2 R-SSC-9693198 https://reactome.org/PathwayBrowser/#/R-SSC-9693198 RHOD binds effectors at the plasma membrane IEA Sus scrofa A0A286ZMQ0 R-SSC-1296037 https://reactome.org/PathwayBrowser/#/R-SSC-1296037 Activation of Ca2+ activated Potassium channels with large conductance IEA Sus scrofa A0A286ZMQ1 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A286ZMQ1 R-SSC-390930 https://reactome.org/PathwayBrowser/#/R-SSC-390930 5-HT2 receptor can bind serotonin IEA Sus scrofa A0A286ZMQ1 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A286ZMQ1 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A286ZMQ7 R-SSC-8876454 https://reactome.org/PathwayBrowser/#/R-SSC-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Sus scrofa A0A286ZMR4 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A286ZMR4 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A286ZMR4 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A286ZMR4 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A286ZMR4 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A286ZMT8 R-SSC-1226094 https://reactome.org/PathwayBrowser/#/R-SSC-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Sus scrofa A0A286ZMT8 R-SSC-1227670 https://reactome.org/PathwayBrowser/#/R-SSC-1227670 Recruitment of HDAC1 by p130 (RBL2) IEA Sus scrofa A0A286ZMT8 R-SSC-1362261 https://reactome.org/PathwayBrowser/#/R-SSC-1362261 p130 (RBL2) associates with MuvB to form DREAM complex IEA Sus scrofa A0A286ZMT8 R-SSC-1363276 https://reactome.org/PathwayBrowser/#/R-SSC-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Sus scrofa A0A286ZMT8 R-SSC-1363303 https://reactome.org/PathwayBrowser/#/R-SSC-1363303 p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 IEA Sus scrofa A0A286ZMT8 R-SSC-1363306 https://reactome.org/PathwayBrowser/#/R-SSC-1363306 p130 (RBL2) binds Cyclin E/A:CDK2 IEA Sus scrofa A0A286ZMT8 R-SSC-1363328 https://reactome.org/PathwayBrowser/#/R-SSC-1363328 Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex IEA Sus scrofa A0A286ZMT8 R-SSC-1363331 https://reactome.org/PathwayBrowser/#/R-SSC-1363331 Ubiquitination of p130 (RBL2) by SCF (Skp2) IEA Sus scrofa A0A286ZMU4 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A286ZMU4 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A286ZMU4 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A286ZMU4 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A286ZMU4 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A286ZMU4 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A286ZMU4 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A286ZMU4 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A286ZMU4 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A286ZMU4 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZMU4 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A286ZMU4 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A286ZMU4 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A286ZMU4 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A286ZMU4 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A286ZMU4 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A286ZMU4 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A286ZMU4 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A286ZMU4 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A286ZMU4 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A286ZMU4 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A286ZMU4 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A286ZMU4 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A286ZMU4 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A286ZMU4 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A286ZMU4 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A286ZMU4 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A286ZMU4 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A286ZMU4 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A286ZMU4 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A286ZMU4 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A286ZMU4 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A286ZMU4 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A286ZMU4 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A286ZMU4 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A286ZMU4 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A286ZMU4 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A286ZMU4 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A286ZMU4 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A286ZMU4 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A286ZMU4 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A286ZMU4 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A286ZMU4 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A286ZMU4 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A286ZMU4 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A286ZMU4 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A286ZMU4 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A286ZMV3 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZMV3 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A286ZMV3 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZMV3 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A286ZMV8 R-SSC-5675373 https://reactome.org/PathwayBrowser/#/R-SSC-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Sus scrofa A0A286ZMW3 R-SSC-6800299 https://reactome.org/PathwayBrowser/#/R-SSC-6800299 HGFAC cleaves pro-HGF to form HGF dimer IEA Sus scrofa A0A286ZMW6 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A286ZMX2 R-SSC-141423 https://reactome.org/PathwayBrowser/#/R-SSC-141423 Binding of the MCC complex to the APC/C complex IEA Sus scrofa A0A286ZMX2 R-SSC-174057 https://reactome.org/PathwayBrowser/#/R-SSC-174057 Multiubiquitination of APC/C-associated Cdh1 IEA Sus scrofa A0A286ZMX2 R-SSC-174058 https://reactome.org/PathwayBrowser/#/R-SSC-174058 Degradation of multiubiquitinated Cdh1 IEA Sus scrofa A0A286ZMX2 R-SSC-174070 https://reactome.org/PathwayBrowser/#/R-SSC-174070 Association of Cdh1 with the APC/C IEA Sus scrofa A0A286ZMX2 R-SSC-174079 https://reactome.org/PathwayBrowser/#/R-SSC-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Sus scrofa A0A286ZMX2 R-SSC-174088 https://reactome.org/PathwayBrowser/#/R-SSC-174088 Association of cell cycle proteins with the APC/C:Cdh1 complex IEA Sus scrofa A0A286ZMX2 R-SSC-174104 https://reactome.org/PathwayBrowser/#/R-SSC-174104 Ubiquitination of Cyclin A by APC/C:Cdc20 complex IEA Sus scrofa A0A286ZMX2 R-SSC-174105 https://reactome.org/PathwayBrowser/#/R-SSC-174105 Degradation of multiubiquitinated cell cycle proteins IEA Sus scrofa A0A286ZMX2 R-SSC-174119 https://reactome.org/PathwayBrowser/#/R-SSC-174119 Free APC/C phosphorylated by Plk1 IEA Sus scrofa A0A286ZMX2 R-SSC-174120 https://reactome.org/PathwayBrowser/#/R-SSC-174120 Association of Cyclin B:Cdc2 with Cdc20:APC/C complex IEA Sus scrofa A0A286ZMX2 R-SSC-174121 https://reactome.org/PathwayBrowser/#/R-SSC-174121 Association of Securin with Cdc20:APC/C complex IEA Sus scrofa A0A286ZMX2 R-SSC-174132 https://reactome.org/PathwayBrowser/#/R-SSC-174132 Free APC/C phosphorylated by Cyclin B:Cdc2 IEA Sus scrofa A0A286ZMX2 R-SSC-174139 https://reactome.org/PathwayBrowser/#/R-SSC-174139 Dissociation of phospho-Cdh1 from the APC/C complex IEA Sus scrofa A0A286ZMX2 R-SSC-174144 https://reactome.org/PathwayBrowser/#/R-SSC-174144 Ubiquitination of Securin by phospho-APC/C:Cdc20 complex IEA Sus scrofa A0A286ZMX2 R-SSC-174157 https://reactome.org/PathwayBrowser/#/R-SSC-174157 Degradation of multiubiquitinated Cyclin B IEA Sus scrofa A0A286ZMX2 R-SSC-174171 https://reactome.org/PathwayBrowser/#/R-SSC-174171 Association of Cyclin A with the APC/C IEA Sus scrofa A0A286ZMX2 R-SSC-174195 https://reactome.org/PathwayBrowser/#/R-SSC-174195 Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex IEA Sus scrofa A0A286ZMX2 R-SSC-174202 https://reactome.org/PathwayBrowser/#/R-SSC-174202 Degradation of multiubiquitinated Securin IEA Sus scrofa A0A286ZMX2 R-SSC-174224 https://reactome.org/PathwayBrowser/#/R-SSC-174224 Dissociation of Cdc20 from APC/C complex IEA Sus scrofa A0A286ZMX2 R-SSC-174227 https://reactome.org/PathwayBrowser/#/R-SSC-174227 Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex IEA Sus scrofa A0A286ZMX2 R-SSC-174238 https://reactome.org/PathwayBrowser/#/R-SSC-174238 Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 IEA Sus scrofa A0A286ZMX2 R-SSC-174255 https://reactome.org/PathwayBrowser/#/R-SSC-174255 Degradation multiubiquitinated Cyclin A IEA Sus scrofa A0A286ZMX2 R-SSC-179417 https://reactome.org/PathwayBrowser/#/R-SSC-179417 Multiubiquitination of Nek2A IEA Sus scrofa A0A286ZMX2 R-SSC-179421 https://reactome.org/PathwayBrowser/#/R-SSC-179421 Degradation of multiubiquitinated Nek2A IEA Sus scrofa A0A286ZMX2 R-SSC-188191 https://reactome.org/PathwayBrowser/#/R-SSC-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Sus scrofa A0A286ZMX2 R-SSC-188371 https://reactome.org/PathwayBrowser/#/R-SSC-188371 Association of Cyclin A:Cdk2 with Cdh1 IEA Sus scrofa A0A286ZMX2 R-SSC-3788705 https://reactome.org/PathwayBrowser/#/R-SSC-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Sus scrofa A0A286ZMX2 R-SSC-3788708 https://reactome.org/PathwayBrowser/#/R-SSC-3788708 CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 IEA Sus scrofa A0A286ZMX2 R-SSC-3788724 https://reactome.org/PathwayBrowser/#/R-SSC-3788724 Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 IEA Sus scrofa A0A286ZMX2 R-SSC-3788725 https://reactome.org/PathwayBrowser/#/R-SSC-3788725 Cdh1:APC/C complex binds EHMT1:EHMT2 IEA Sus scrofa A0A286ZMX2 R-SSC-68712 https://reactome.org/PathwayBrowser/#/R-SSC-68712 The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 IEA Sus scrofa A0A286ZMX2 R-SSC-69015 https://reactome.org/PathwayBrowser/#/R-SSC-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Sus scrofa A0A286ZMX2 R-SSC-8852127 https://reactome.org/PathwayBrowser/#/R-SSC-8852127 UBA6 conjugates ubiquitin to cytosolic E2 enzymes IEA Sus scrofa A0A286ZMX2 R-SSC-8852129 https://reactome.org/PathwayBrowser/#/R-SSC-8852129 UBA1 conjugates ubiquitin to cytosolic E2 enzymes IEA Sus scrofa A0A286ZMX2 R-SSC-8852130 https://reactome.org/PathwayBrowser/#/R-SSC-8852130 UBA1 conjugates ubiquitin to nuclear E2 enzymes IEA Sus scrofa A0A286ZMX2 R-SSC-9686969 https://reactome.org/PathwayBrowser/#/R-SSC-9686969 APC/C:Cdh1 polyubiquitinates SKP2 IEA Sus scrofa A0A286ZMX2 R-SSC-9686980 https://reactome.org/PathwayBrowser/#/R-SSC-9686980 RB1 recruits APC/C:Cdh1 complex to SKP2 IEA Sus scrofa A0A286ZMX2 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZMX2 R-SSC-983152 https://reactome.org/PathwayBrowser/#/R-SSC-983152 Transfer of ubiquitin from E1 to E2 IEA Sus scrofa A0A286ZMX2 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZMX2 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A286ZMX3 R-SSC-445753 https://reactome.org/PathwayBrowser/#/R-SSC-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Sus scrofa A0A286ZMX3 R-SSC-446130 https://reactome.org/PathwayBrowser/#/R-SSC-446130 Interleukin-1 receptor type 2 binds Interleukin 1 IEA Sus scrofa A0A286ZMX3 R-SSC-446634 https://reactome.org/PathwayBrowser/#/R-SSC-446634 IRAK4 is activated by autophosphorylation IEA Sus scrofa A0A286ZMX3 R-SSC-446648 https://reactome.org/PathwayBrowser/#/R-SSC-446648 IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 IEA Sus scrofa A0A286ZMX3 R-SSC-446684 https://reactome.org/PathwayBrowser/#/R-SSC-446684 IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation IEA Sus scrofa A0A286ZMX3 R-SSC-446692 https://reactome.org/PathwayBrowser/#/R-SSC-446692 IRAK1 binds to MYD88 within the IL1R complex IEA Sus scrofa A0A286ZMX3 R-SSC-446694 https://reactome.org/PathwayBrowser/#/R-SSC-446694 IRAK4 phosphorylates IRAK1 IEA Sus scrofa A0A286ZMX3 R-SSC-446701 https://reactome.org/PathwayBrowser/#/R-SSC-446701 IRAK4-activated IRAK1 autophosphorylates IEA Sus scrofa A0A286ZMX3 R-SSC-446862 https://reactome.org/PathwayBrowser/#/R-SSC-446862 Hyperphosphorylated IRAK1 associates with TRAF6 IEA Sus scrofa A0A286ZMX3 R-SSC-446868 https://reactome.org/PathwayBrowser/#/R-SSC-446868 The Interleukin 1 receptor complex binds Tollip IEA Sus scrofa A0A286ZMX3 R-SSC-446894 https://reactome.org/PathwayBrowser/#/R-SSC-446894 TRAF6 binding leads to IRAK1:TRAF6 release IEA Sus scrofa A0A286ZMX3 R-SSC-448703 https://reactome.org/PathwayBrowser/#/R-SSC-448703 Interleukin-1 family precursors are cleaved by caspase-1 IEA Sus scrofa A0A286ZMX3 R-SSC-449058 https://reactome.org/PathwayBrowser/#/R-SSC-449058 Interleukin-1 family are secreted IEA Sus scrofa A0A286ZMX3 R-SSC-507719 https://reactome.org/PathwayBrowser/#/R-SSC-507719 p62:MEKK3 binds to TRAF6 IEA Sus scrofa A0A286ZMX3 R-SSC-5660663 https://reactome.org/PathwayBrowser/#/R-SSC-5660663 Caspase-8 cleaves IL1B precursor IEA Sus scrofa A0A286ZMX6 R-SSC-5661217 https://reactome.org/PathwayBrowser/#/R-SSC-5661217 MT1A binds zinc IEA Sus scrofa A0A286ZMX6 R-SSC-5661230 https://reactome.org/PathwayBrowser/#/R-SSC-5661230 MT1A binds arsenic IEA Sus scrofa A0A286ZMY6 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A286ZMY6 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa A0A286ZMZ4 R-SSC-1299318 https://reactome.org/PathwayBrowser/#/R-SSC-1299318 Activation of TASK IEA Sus scrofa A0A286ZMZ4 R-SSC-5578910 https://reactome.org/PathwayBrowser/#/R-SSC-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Sus scrofa A0A286ZN03 R-SSC-156826 https://reactome.org/PathwayBrowser/#/R-SSC-156826 Dissociation of L13a from the 60s ribosomal subunit IEA Sus scrofa A0A286ZN03 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A286ZN03 R-SSC-6791218 https://reactome.org/PathwayBrowser/#/R-SSC-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Sus scrofa A0A286ZN03 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A286ZN03 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A286ZN03 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A286ZN03 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A286ZN03 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A286ZN03 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A286ZN03 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A286ZN03 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A286ZN07 R-SSC-5682388 https://reactome.org/PathwayBrowser/#/R-SSC-5682388 Autophagosome maturation IEA Sus scrofa A0A286ZN07 R-SSC-917693 https://reactome.org/PathwayBrowser/#/R-SSC-917693 ESCRT Disassembly IEA Sus scrofa A0A286ZN07 R-SSC-917700 https://reactome.org/PathwayBrowser/#/R-SSC-917700 MVB Vesicle Formation IEA Sus scrofa A0A286ZN07 R-SSC-9647619 https://reactome.org/PathwayBrowser/#/R-SSC-9647619 GSDMD forms ring‐shaped oligomers IEA Sus scrofa A0A286ZN07 R-SSC-9668389 https://reactome.org/PathwayBrowser/#/R-SSC-9668389 VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations IEA Sus scrofa A0A286ZN07 R-SSC-9668395 https://reactome.org/PathwayBrowser/#/R-SSC-9668395 CHMP7 binds CC2D1B IEA Sus scrofa A0A286ZN07 R-SSC-9668405 https://reactome.org/PathwayBrowser/#/R-SSC-9668405 SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin IEA Sus scrofa A0A286ZN07 R-SSC-9668419 https://reactome.org/PathwayBrowser/#/R-SSC-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Sus scrofa A0A286ZN11 R-SSC-426489 https://reactome.org/PathwayBrowser/#/R-SSC-426489 RISC binds inexactly matching target RNAs IEA Sus scrofa A0A286ZN11 R-SSC-426522 https://reactome.org/PathwayBrowser/#/R-SSC-426522 Nonendonucleolytic RISC binds exactly matching target RNAs IEA Sus scrofa A0A286ZN27 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A286ZN27 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A286ZN27 R-SSC-190520 https://reactome.org/PathwayBrowser/#/R-SSC-190520 Association of Golgi transport vesicles with microtubules IEA Sus scrofa A0A286ZN27 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A286ZN27 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A286ZN27 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A286ZN27 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A286ZN27 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A286ZN27 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A286ZN27 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A286ZN27 R-SSC-5610733 https://reactome.org/PathwayBrowser/#/R-SSC-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules IEA Sus scrofa A0A286ZN27 R-SSC-5610767 https://reactome.org/PathwayBrowser/#/R-SSC-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Sus scrofa A0A286ZN27 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa A0A286ZN27 R-SSC-5618328 https://reactome.org/PathwayBrowser/#/R-SSC-5618328 ATAT acetylates microtubules IEA Sus scrofa A0A286ZN27 R-SSC-5618331 https://reactome.org/PathwayBrowser/#/R-SSC-5618331 HDAC6 deacetylates microtubules IEA Sus scrofa A0A286ZN27 R-SSC-5624949 https://reactome.org/PathwayBrowser/#/R-SSC-5624949 Assembly of the anterograde IFT train IEA Sus scrofa A0A286ZN27 R-SSC-5624952 https://reactome.org/PathwayBrowser/#/R-SSC-5624952 Assembly of the retrograde IFT train IEA Sus scrofa A0A286ZN27 R-SSC-5625416 https://reactome.org/PathwayBrowser/#/R-SSC-5625416 Anterograde IFT IEA Sus scrofa A0A286ZN27 R-SSC-5625421 https://reactome.org/PathwayBrowser/#/R-SSC-5625421 The anterograde IFT train dissociates IEA Sus scrofa A0A286ZN27 R-SSC-5625424 https://reactome.org/PathwayBrowser/#/R-SSC-5625424 The retrograde IFT train dissociates IEA Sus scrofa A0A286ZN27 R-SSC-5625426 https://reactome.org/PathwayBrowser/#/R-SSC-5625426 Retrograde IFT IEA Sus scrofa A0A286ZN27 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A286ZN27 R-SSC-5672329 https://reactome.org/PathwayBrowser/#/R-SSC-5672329 IQGAP1 binds CLIP1 and microtubules IEA Sus scrofa A0A286ZN27 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa A0A286ZN27 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A286ZN27 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa A0A286ZN27 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa A0A286ZN27 R-SSC-8852280 https://reactome.org/PathwayBrowser/#/R-SSC-8852280 GTSE1 binds microtubule lattice in interphase cells IEA Sus scrofa A0A286ZN27 R-SSC-8852298 https://reactome.org/PathwayBrowser/#/R-SSC-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends IEA Sus scrofa A0A286ZN27 R-SSC-8852306 https://reactome.org/PathwayBrowser/#/R-SSC-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Sus scrofa A0A286ZN27 R-SSC-8865774 https://reactome.org/PathwayBrowser/#/R-SSC-8865774 TTLLs polyglutamylate tubulin IEA Sus scrofa A0A286ZN27 R-SSC-8867370 https://reactome.org/PathwayBrowser/#/R-SSC-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Sus scrofa A0A286ZN27 R-SSC-9646679 https://reactome.org/PathwayBrowser/#/R-SSC-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Sus scrofa A0A286ZN27 R-SSC-9646685 https://reactome.org/PathwayBrowser/#/R-SSC-9646685 Aggresome dissociates from dynein and microtubule IEA Sus scrofa A0A286ZN27 R-SSC-9648017 https://reactome.org/PathwayBrowser/#/R-SSC-9648017 EML4 binds to microtubules IEA Sus scrofa A0A286ZN27 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A286ZN27 R-SSC-9668419 https://reactome.org/PathwayBrowser/#/R-SSC-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Sus scrofa A0A286ZN27 R-SSC-983259 https://reactome.org/PathwayBrowser/#/R-SSC-983259 Kinesins move along microtubules consuming ATP IEA Sus scrofa A0A286ZN27 R-SSC-983266 https://reactome.org/PathwayBrowser/#/R-SSC-983266 Kinesins bind microtubules IEA Sus scrofa A0A286ZN27 R-SSC-9836404 https://reactome.org/PathwayBrowser/#/R-SSC-9836404 p-PKR dimer phosphorylates MAPT IEA Sus scrofa A0A286ZN28 R-SSC-9695890 https://reactome.org/PathwayBrowser/#/R-SSC-9695890 SPNS2,MFSD2B transport S1P from cytosol to extracellular region IEA Sus scrofa A0A286ZN41 R-SSC-9639287 https://reactome.org/PathwayBrowser/#/R-SSC-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Sus scrofa A0A286ZN41 R-SSC-9640195 https://reactome.org/PathwayBrowser/#/R-SSC-9640195 RRAGA,B hydrolyzes GTP IEA Sus scrofa A0A286ZN41 R-SSC-9640237 https://reactome.org/PathwayBrowser/#/R-SSC-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Sus scrofa A0A286ZN41 R-SSC-9640254 https://reactome.org/PathwayBrowser/#/R-SSC-9640254 BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 IEA Sus scrofa A0A286ZN41 R-SSC-9657619 https://reactome.org/PathwayBrowser/#/R-SSC-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 IEA Sus scrofa A0A286ZN52 R-SSC-1168640 https://reactome.org/PathwayBrowser/#/R-SSC-1168640 Ubiquitinated IkB is degraded IEA Sus scrofa A0A286ZN52 R-SSC-1234159 https://reactome.org/PathwayBrowser/#/R-SSC-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Sus scrofa A0A286ZN52 R-SSC-1236970 https://reactome.org/PathwayBrowser/#/R-SSC-1236970 Proteasomal clevage of exogenous antigen (26S proteasome catalyst) IEA Sus scrofa A0A286ZN52 R-SSC-1504193 https://reactome.org/PathwayBrowser/#/R-SSC-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Sus scrofa A0A286ZN52 R-SSC-174058 https://reactome.org/PathwayBrowser/#/R-SSC-174058 Degradation of multiubiquitinated Cdh1 IEA Sus scrofa A0A286ZN52 R-SSC-174105 https://reactome.org/PathwayBrowser/#/R-SSC-174105 Degradation of multiubiquitinated cell cycle proteins IEA Sus scrofa A0A286ZN52 R-SSC-174202 https://reactome.org/PathwayBrowser/#/R-SSC-174202 Degradation of multiubiquitinated Securin IEA Sus scrofa A0A286ZN52 R-SSC-174255 https://reactome.org/PathwayBrowser/#/R-SSC-174255 Degradation multiubiquitinated Cyclin A IEA Sus scrofa A0A286ZN52 R-SSC-187574 https://reactome.org/PathwayBrowser/#/R-SSC-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Sus scrofa A0A286ZN52 R-SSC-188191 https://reactome.org/PathwayBrowser/#/R-SSC-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Sus scrofa A0A286ZN52 R-SSC-209061 https://reactome.org/PathwayBrowser/#/R-SSC-209061 Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex IEA Sus scrofa A0A286ZN52 R-SSC-2130282 https://reactome.org/PathwayBrowser/#/R-SSC-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Sus scrofa A0A286ZN52 R-SSC-264458 https://reactome.org/PathwayBrowser/#/R-SSC-264458 Proteasome mediated degradation of COP1 IEA Sus scrofa A0A286ZN52 R-SSC-353125 https://reactome.org/PathwayBrowser/#/R-SSC-353125 26S proteosome degrades ODC holoenzyme complex IEA Sus scrofa A0A286ZN52 R-SSC-3640874 https://reactome.org/PathwayBrowser/#/R-SSC-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Sus scrofa A0A286ZN52 R-SSC-450466 https://reactome.org/PathwayBrowser/#/R-SSC-450466 AUF1:mRNA complex is destroyed IEA Sus scrofa A0A286ZN52 R-SSC-4608855 https://reactome.org/PathwayBrowser/#/R-SSC-4608855 PRICKLE1 is degraded by the proteasome IEA Sus scrofa A0A286ZN52 R-SSC-4641256 https://reactome.org/PathwayBrowser/#/R-SSC-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Sus scrofa A0A286ZN52 R-SSC-4641260 https://reactome.org/PathwayBrowser/#/R-SSC-4641260 Ubiquitinated DVL1 is degraded by the proteasome IEA Sus scrofa A0A286ZN52 R-SSC-5362448 https://reactome.org/PathwayBrowser/#/R-SSC-5362448 Hh C-terminal fragments are degraded by the proteasome IEA Sus scrofa A0A286ZN52 R-SSC-5607724 https://reactome.org/PathwayBrowser/#/R-SSC-5607724 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex IEA Sus scrofa A0A286ZN52 R-SSC-5607731 https://reactome.org/PathwayBrowser/#/R-SSC-5607731 26S proteasome processes p-7S-p100:RELB to form p52:RELB IEA Sus scrofa A0A286ZN52 R-SSC-5610754 https://reactome.org/PathwayBrowser/#/R-SSC-5610754 GLI3 is partially degraded by the proteasome to yield the GLI3 repressor IEA Sus scrofa A0A286ZN52 R-SSC-5610758 https://reactome.org/PathwayBrowser/#/R-SSC-5610758 GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP IEA Sus scrofa A0A286ZN52 R-SSC-5610760 https://reactome.org/PathwayBrowser/#/R-SSC-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Sus scrofa A0A286ZN52 R-SSC-5635854 https://reactome.org/PathwayBrowser/#/R-SSC-5635854 GLI2,3 are degraded by the proteasome IEA Sus scrofa A0A286ZN52 R-SSC-5635868 https://reactome.org/PathwayBrowser/#/R-SSC-5635868 ub-GLI is degraded by the proteasome IEA Sus scrofa A0A286ZN52 R-SSC-5658430 https://reactome.org/PathwayBrowser/#/R-SSC-5658430 NF1 is degraded by the proteasome IEA Sus scrofa A0A286ZN52 R-SSC-5665854 https://reactome.org/PathwayBrowser/#/R-SSC-5665854 ADRM1:26S proteaseome binds UCHL5 IEA Sus scrofa A0A286ZN52 R-SSC-5665871 https://reactome.org/PathwayBrowser/#/R-SSC-5665871 ADRM1 binds 26S proteasome IEA Sus scrofa A0A286ZN52 R-SSC-5668481 https://reactome.org/PathwayBrowser/#/R-SSC-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Sus scrofa A0A286ZN52 R-SSC-5668520 https://reactome.org/PathwayBrowser/#/R-SSC-5668520 26Sproteasome degrades K48polyUb-NIK IEA Sus scrofa A0A286ZN52 R-SSC-5687112 https://reactome.org/PathwayBrowser/#/R-SSC-5687112 MAPK6 is degraded by the 26S proteasome IEA Sus scrofa A0A286ZN52 R-SSC-5689539 https://reactome.org/PathwayBrowser/#/R-SSC-5689539 ADRM1:26S proteaseome binds USP14 IEA Sus scrofa A0A286ZN52 R-SSC-68825 https://reactome.org/PathwayBrowser/#/R-SSC-68825 Ubiquitinated geminin is degraded by the proteasome IEA Sus scrofa A0A286ZN52 R-SSC-68948 https://reactome.org/PathwayBrowser/#/R-SSC-68948 Ubiquitinated Orc1 is degraded by the proteasome IEA Sus scrofa A0A286ZN52 R-SSC-69016 https://reactome.org/PathwayBrowser/#/R-SSC-69016 Ubiquitinated Cdc6 is degraded by the proteasome IEA Sus scrofa A0A286ZN52 R-SSC-69600 https://reactome.org/PathwayBrowser/#/R-SSC-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Sus scrofa A0A286ZN52 R-SSC-75825 https://reactome.org/PathwayBrowser/#/R-SSC-75825 Proteasome mediated degradation of Cyclin D1 IEA Sus scrofa A0A286ZN52 R-SSC-8850992 https://reactome.org/PathwayBrowser/#/R-SSC-8850992 Proteasome degrades polyubiquitinated PTEN IEA Sus scrofa A0A286ZN52 R-SSC-8852354 https://reactome.org/PathwayBrowser/#/R-SSC-8852354 GTSE1 facilitates proteasome-mediated degradation of TP53 IEA Sus scrofa A0A286ZN52 R-SSC-8854044 https://reactome.org/PathwayBrowser/#/R-SSC-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Sus scrofa A0A286ZN52 R-SSC-8854071 https://reactome.org/PathwayBrowser/#/R-SSC-8854071 Proteasome-mediated degradation of PolyUb-FBXL7 IEA Sus scrofa A0A286ZN52 R-SSC-8866553 https://reactome.org/PathwayBrowser/#/R-SSC-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Sus scrofa A0A286ZN52 R-SSC-8932355 https://reactome.org/PathwayBrowser/#/R-SSC-8932355 26S proteasome degrades Ub-NFE2L2 IEA Sus scrofa A0A286ZN52 R-SSC-8939801 https://reactome.org/PathwayBrowser/#/R-SSC-8939801 26S proteasome degrades PolyUb-RUNX2 IEA Sus scrofa A0A286ZN52 R-SSC-8952408 https://reactome.org/PathwayBrowser/#/R-SSC-8952408 Polyubiquitinated RUNX3 is degraded by the proteasome IEA Sus scrofa A0A286ZN52 R-SSC-8956140 https://reactome.org/PathwayBrowser/#/R-SSC-8956140 NEDD8 and UBD bind NUB1 and the 26S proteasome IEA Sus scrofa A0A286ZN52 R-SSC-8956184 https://reactome.org/PathwayBrowser/#/R-SSC-8956184 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates IEA Sus scrofa A0A286ZN52 R-SSC-8957265 https://reactome.org/PathwayBrowser/#/R-SSC-8957265 26S proteasome degrades TP73 polyubiquitinated by ITCH IEA Sus scrofa A0A286ZN52 R-SSC-9755303 https://reactome.org/PathwayBrowser/#/R-SSC-9755303 26S proteasome degrades HIFalpha IEA Sus scrofa A0A286ZN52 R-SSC-9755306 https://reactome.org/PathwayBrowser/#/R-SSC-9755306 ub UBXN7 is degraded by the 26S proteasome IEA Sus scrofa A0A286ZN52 R-SSC-9762096 https://reactome.org/PathwayBrowser/#/R-SSC-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Sus scrofa A0A286ZN52 R-SSC-983150 https://reactome.org/PathwayBrowser/#/R-SSC-983150 Proteasomal cleavage of substrate IEA Sus scrofa A0A286ZN52 R-SSC-9907919 https://reactome.org/PathwayBrowser/#/R-SSC-9907919 Formation of the preholoproteasome IEA Sus scrofa A0A286ZN52 R-SSC-9907940 https://reactome.org/PathwayBrowser/#/R-SSC-9907940 Formation of the preholothymoproteasome IEA Sus scrofa A0A286ZN52 R-SSC-9907941 https://reactome.org/PathwayBrowser/#/R-SSC-9907941 Fromation of the preholoimmunoproteasome IEA Sus scrofa A0A286ZN52 R-SSC-9908709 https://reactome.org/PathwayBrowser/#/R-SSC-9908709 Formation of the PA28-alpha-beta-20S proteasome IEA Sus scrofa A0A286ZN52 R-SSC-9908721 https://reactome.org/PathwayBrowser/#/R-SSC-9908721 Formation of the PA28gamma-20S proteasome IEA Sus scrofa A0A286ZN52 R-SSC-9912636 https://reactome.org/PathwayBrowser/#/R-SSC-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Sus scrofa A0A286ZN52 R-SSC-9912655 https://reactome.org/PathwayBrowser/#/R-SSC-9912655 Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) IEA Sus scrofa A0A286ZN52 R-SSC-9912747 https://reactome.org/PathwayBrowser/#/R-SSC-9912747 Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) IEA Sus scrofa A0A286ZN52 R-SSC-9912751 https://reactome.org/PathwayBrowser/#/R-SSC-9912751 Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) IEA Sus scrofa A0A286ZN52 R-SSC-9934893 https://reactome.org/PathwayBrowser/#/R-SSC-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 IEA Sus scrofa A0A286ZN71 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa A0A286ZN71 R-SSC-3928627 https://reactome.org/PathwayBrowser/#/R-SSC-3928627 EPHB phosphorylates TIAM1 IEA Sus scrofa A0A286ZN71 R-SSC-3928642 https://reactome.org/PathwayBrowser/#/R-SSC-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa A0A286ZN71 R-SSC-3928645 https://reactome.org/PathwayBrowser/#/R-SSC-3928645 EPHB:NMDAR binds TIAM1 IEA Sus scrofa A0A286ZN71 R-SSC-4093327 https://reactome.org/PathwayBrowser/#/R-SSC-4093327 EPHA binds TIAM1 IEA Sus scrofa A0A286ZN71 R-SSC-4093336 https://reactome.org/PathwayBrowser/#/R-SSC-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa A0A286ZN71 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa A0A286ZN71 R-SSC-8980691 https://reactome.org/PathwayBrowser/#/R-SSC-8980691 RHOA GEFs activate RHOA IEA Sus scrofa A0A286ZN71 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A286ZN71 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa A0A286ZN71 R-SSC-9014296 https://reactome.org/PathwayBrowser/#/R-SSC-9014296 RAC2 GEFs activate RAC2 IEA Sus scrofa A0A286ZN71 R-SSC-9018804 https://reactome.org/PathwayBrowser/#/R-SSC-9018804 RAC3 GEFs activate RAC3 IEA Sus scrofa A0A286ZN77 R-SSC-8854222 https://reactome.org/PathwayBrowser/#/R-SSC-8854222 TBC1D3 associates with RAB5 IEA Sus scrofa A0A286ZN77 R-SSC-8875659 https://reactome.org/PathwayBrowser/#/R-SSC-8875659 RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane IEA Sus scrofa A0A286ZN77 R-SSC-8875661 https://reactome.org/PathwayBrowser/#/R-SSC-8875661 GGA3 associates with activated MET receptor IEA Sus scrofa A0A286ZN81 R-SSC-380278 https://reactome.org/PathwayBrowser/#/R-SSC-380278 CCNB1:p-T160-CDK1 phosphorylates NUMA1 IEA Sus scrofa A0A286ZN81 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A286ZN81 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A286ZN85 R-SSC-1112538 https://reactome.org/PathwayBrowser/#/R-SSC-1112538 Phosphorylated STAT1, STAT3 form dimers IEA Sus scrofa A0A286ZN85 R-SSC-1112565 https://reactome.org/PathwayBrowser/#/R-SSC-1112565 Tyrosine phosphorylated IL6ST binds STAT1,STAT3 IEA Sus scrofa A0A286ZN85 R-SSC-1112587 https://reactome.org/PathwayBrowser/#/R-SSC-1112587 STAT1 and STAT3 dimers translocate to the nucleus IEA Sus scrofa A0A286ZN85 R-SSC-1112602 https://reactome.org/PathwayBrowser/#/R-SSC-1112602 Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor IEA Sus scrofa A0A286ZN85 R-SSC-1112604 https://reactome.org/PathwayBrowser/#/R-SSC-1112604 Phosphorylated STATs are released IEA Sus scrofa A0A286ZN85 R-SSC-1112727 https://reactome.org/PathwayBrowser/#/R-SSC-1112727 Serine phosphorylation of STATs IEA Sus scrofa A0A286ZN85 R-SSC-1169406 https://reactome.org/PathwayBrowser/#/R-SSC-1169406 ISGylation of host proteins IEA Sus scrofa A0A286ZN85 R-SSC-1433456 https://reactome.org/PathwayBrowser/#/R-SSC-1433456 Recruitment of STATs IEA Sus scrofa A0A286ZN85 R-SSC-1470009 https://reactome.org/PathwayBrowser/#/R-SSC-1470009 Phosphorylation of STATs IEA Sus scrofa A0A286ZN85 R-SSC-1470010 https://reactome.org/PathwayBrowser/#/R-SSC-1470010 Dimerization of STATs IEA Sus scrofa A0A286ZN85 R-SSC-1470012 https://reactome.org/PathwayBrowser/#/R-SSC-1470012 Disassociation and translocation of STATs to the nucleus IEA Sus scrofa A0A286ZN85 R-SSC-1678841 https://reactome.org/PathwayBrowser/#/R-SSC-1678841 Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 IEA Sus scrofa A0A286ZN85 R-SSC-380782 https://reactome.org/PathwayBrowser/#/R-SSC-380782 STAT binds to the active receptor IEA Sus scrofa A0A286ZN85 R-SSC-6788571 https://reactome.org/PathwayBrowser/#/R-SSC-6788571 STAT1,STAT3,STAT6 bind IL13:IL13R type II IEA Sus scrofa A0A286ZN85 R-SSC-6788582 https://reactome.org/PathwayBrowser/#/R-SSC-6788582 STAT1,STAT3,STAT6 phosphorylation IEA Sus scrofa A0A286ZN85 R-SSC-6788622 https://reactome.org/PathwayBrowser/#/R-SSC-6788622 p-Y-STATs dimerize IEA Sus scrofa A0A286ZN85 R-SSC-6788623 https://reactome.org/PathwayBrowser/#/R-SSC-6788623 p-Y-STATs translocate to nucleus IEA Sus scrofa A0A286ZN85 R-SSC-6788628 https://reactome.org/PathwayBrowser/#/R-SSC-6788628 p-Y-STATs dissociate IEA Sus scrofa A0A286ZN85 R-SSC-873917 https://reactome.org/PathwayBrowser/#/R-SSC-873917 Translocation of STAT1 dimer to nucleus IEA Sus scrofa A0A286ZN85 R-SSC-873921 https://reactome.org/PathwayBrowser/#/R-SSC-873921 Binding of STAT1 to p-IFNGR1 IEA Sus scrofa A0A286ZN85 R-SSC-873922 https://reactome.org/PathwayBrowser/#/R-SSC-873922 Phosphorylation of STAT1 by JAK kinases IEA Sus scrofa A0A286ZN85 R-SSC-873927 https://reactome.org/PathwayBrowser/#/R-SSC-873927 Release of STAT1 dimer from active receptor unit IEA Sus scrofa A0A286ZN85 R-SSC-877281 https://reactome.org/PathwayBrowser/#/R-SSC-877281 PIAS1 binds p-STAT1 dimer IEA Sus scrofa A0A286ZN85 R-SSC-8950441 https://reactome.org/PathwayBrowser/#/R-SSC-8950441 p-Y701-STAT1 and p-Y705-STAT3 dissociate from IL27:IL27 receptor IEA Sus scrofa A0A286ZN85 R-SSC-8950453 https://reactome.org/PathwayBrowser/#/R-SSC-8950453 JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 IEA Sus scrofa A0A286ZN85 R-SSC-8950485 https://reactome.org/PathwayBrowser/#/R-SSC-8950485 STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction IEA Sus scrofa A0A286ZN85 R-SSC-8950518 https://reactome.org/PathwayBrowser/#/R-SSC-8950518 STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex IEA Sus scrofa A0A286ZN85 R-SSC-8950522 https://reactome.org/PathwayBrowser/#/R-SSC-8950522 p-STAT1:p-STAT4 translocates to the nucleus IEA Sus scrofa A0A286ZN85 R-SSC-8950733 https://reactome.org/PathwayBrowser/#/R-SSC-8950733 p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus IEA Sus scrofa A0A286ZN85 R-SSC-8950782 https://reactome.org/PathwayBrowser/#/R-SSC-8950782 p-STAT1 binds p-STAT3 IEA Sus scrofa A0A286ZN85 R-SSC-8983835 https://reactome.org/PathwayBrowser/#/R-SSC-8983835 JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 IEA Sus scrofa A0A286ZN85 R-SSC-8983841 https://reactome.org/PathwayBrowser/#/R-SSC-8983841 STAT1 associates with IL6ST:IL6ST IEA Sus scrofa A0A286ZN85 R-SSC-8983845 https://reactome.org/PathwayBrowser/#/R-SSC-8983845 p-STAT1 dissociates from IL6ST:IL6ST IEA Sus scrofa A0A286ZN85 R-SSC-8983983 https://reactome.org/PathwayBrowser/#/R-SSC-8983983 p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor IEA Sus scrofa A0A286ZN85 R-SSC-8983996 https://reactome.org/PathwayBrowser/#/R-SSC-8983996 STAT1 and STAT4 associate with IL12RB2:IL6ST receptor IEA Sus scrofa A0A286ZN85 R-SSC-8984014 https://reactome.org/PathwayBrowser/#/R-SSC-8984014 JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 IEA Sus scrofa A0A286ZN85 R-SSC-8984021 https://reactome.org/PathwayBrowser/#/R-SSC-8984021 STAT1,STAT3 associate with IL27RA:IL12RB2 receptor IEA Sus scrofa A0A286ZN85 R-SSC-8984023 https://reactome.org/PathwayBrowser/#/R-SSC-8984023 p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor IEA Sus scrofa A0A286ZN85 R-SSC-8985900 https://reactome.org/PathwayBrowser/#/R-SSC-8985900 p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 IEA Sus scrofa A0A286ZN85 R-SSC-8985929 https://reactome.org/PathwayBrowser/#/R-SSC-8985929 IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B IEA Sus scrofa A0A286ZN85 R-SSC-8985943 https://reactome.org/PathwayBrowser/#/R-SSC-8985943 p-Y701-STAT1 dimerizes IEA Sus scrofa A0A286ZN85 R-SSC-8985966 https://reactome.org/PathwayBrowser/#/R-SSC-8985966 p-Y701-STAT1 binds p-Y705-STAT3 IEA Sus scrofa A0A286ZN85 R-SSC-8985981 https://reactome.org/PathwayBrowser/#/R-SSC-8985981 p-Y701-STAT1:p-Y705-STAT3 translocates from the cytosol to the nucleus IEA Sus scrofa A0A286ZN85 R-SSC-8985983 https://reactome.org/PathwayBrowser/#/R-SSC-8985983 p-Y701-STAT1 dimer translocates from the cytosol to the nucleus IEA Sus scrofa A0A286ZN85 R-SSC-8985988 https://reactome.org/PathwayBrowser/#/R-SSC-8985988 IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 IEA Sus scrofa A0A286ZN85 R-SSC-8986985 https://reactome.org/PathwayBrowser/#/R-SSC-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Sus scrofa A0A286ZN85 R-SSC-8987007 https://reactome.org/PathwayBrowser/#/R-SSC-8987007 p-STAT1 dimerizes IEA Sus scrofa A0A286ZN85 R-SSC-8987033 https://reactome.org/PathwayBrowser/#/R-SSC-8987033 p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 IEA Sus scrofa A0A286ZN85 R-SSC-8987080 https://reactome.org/PathwayBrowser/#/R-SSC-8987080 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 IEA Sus scrofa A0A286ZN85 R-SSC-8987097 https://reactome.org/PathwayBrowser/#/R-SSC-8987097 IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3 IEA Sus scrofa A0A286ZN85 R-SSC-8987150 https://reactome.org/PathwayBrowser/#/R-SSC-8987150 IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 IEA Sus scrofa A0A286ZN85 R-SSC-8987218 https://reactome.org/PathwayBrowser/#/R-SSC-8987218 p-STAT1 dimer translocates from the cytosol to the nucleoplasm IEA Sus scrofa A0A286ZN85 R-SSC-8987230 https://reactome.org/PathwayBrowser/#/R-SSC-8987230 p-STAT1 and p-STAT3 dissociates from IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 IEA Sus scrofa A0A286ZN85 R-SSC-8987255 https://reactome.org/PathwayBrowser/#/R-SSC-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Sus scrofa A0A286ZN85 R-SSC-8987266 https://reactome.org/PathwayBrowser/#/R-SSC-8987266 IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 IEA Sus scrofa A0A286ZN85 R-SSC-8987270 https://reactome.org/PathwayBrowser/#/R-SSC-8987270 p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3 IEA Sus scrofa A0A286ZN85 R-SSC-9006870 https://reactome.org/PathwayBrowser/#/R-SSC-9006870 IL21 receptor STAT phosphorylation IEA Sus scrofa A0A286ZN85 R-SSC-9006873 https://reactome.org/PathwayBrowser/#/R-SSC-9006873 IL21 receptor STAT binding IEA Sus scrofa A0A286ZN85 R-SSC-909552 https://reactome.org/PathwayBrowser/#/R-SSC-909552 Phosphorylation of STAT1 at Ser727 IEA Sus scrofa A0A286ZN85 R-SSC-909718 https://reactome.org/PathwayBrowser/#/R-SSC-909718 Formation of p-STAT1 homodimer IEA Sus scrofa A0A286ZN85 R-SSC-909721 https://reactome.org/PathwayBrowser/#/R-SSC-909721 Translocation of ISGF3 complex to nucleus IEA Sus scrofa A0A286ZN85 R-SSC-909722 https://reactome.org/PathwayBrowser/#/R-SSC-909722 Release of p-STAT2:p-STAT1 dimer IEA Sus scrofa A0A286ZN85 R-SSC-909725 https://reactome.org/PathwayBrowser/#/R-SSC-909725 Interaction of IRF9 with p-STAT2:p-STAT1 IEA Sus scrofa A0A286ZN85 R-SSC-913529 https://reactome.org/PathwayBrowser/#/R-SSC-913529 Translocation of p-STAT1:p-STAT1 dimer to nucleus IEA Sus scrofa A0A286ZN85 R-SSC-9710959 https://reactome.org/PathwayBrowser/#/R-SSC-9710959 p-STAT1 dimer binds KPNA1 IEA Sus scrofa A0A286ZN85 R-SSC-9710963 https://reactome.org/PathwayBrowser/#/R-SSC-9710963 p-STAT1dimer:KPNA1 binds KPNB1 IEA Sus scrofa A0A286ZN85 R-SSC-9835443 https://reactome.org/PathwayBrowser/#/R-SSC-9835443 STAT1,STAT3 binds PKR IEA Sus scrofa A0A286ZN85 R-SSC-9865511 https://reactome.org/PathwayBrowser/#/R-SSC-9865511 Phosphorylation of STAT1 on tyrosine-701 is enhanced by p-S172-IKBKE IEA Sus scrofa A0A286ZN85 R-SSC-997309 https://reactome.org/PathwayBrowser/#/R-SSC-997309 Dephosphorylation of STAT1 by SHP2 IEA Sus scrofa A0A286ZN85 R-SSC-997326 https://reactome.org/PathwayBrowser/#/R-SSC-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Sus scrofa A0A286ZN93 R-SSC-5685838 https://reactome.org/PathwayBrowser/#/R-SSC-5685838 CX3 complex binds D-loop structures IEA Sus scrofa A0A286ZN93 R-SSC-5686440 https://reactome.org/PathwayBrowser/#/R-SSC-5686440 MUS81:EME1,EME2 cleaves D-loop IEA Sus scrofa A0A286ZN93 R-SSC-5693539 https://reactome.org/PathwayBrowser/#/R-SSC-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Sus scrofa A0A286ZN93 R-SSC-5693584 https://reactome.org/PathwayBrowser/#/R-SSC-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Sus scrofa A0A286ZN93 R-SSC-5693593 https://reactome.org/PathwayBrowser/#/R-SSC-5693593 D-loop extension by DNA polymerases IEA Sus scrofa A0A286ZN93 R-SSC-5693620 https://reactome.org/PathwayBrowser/#/R-SSC-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Sus scrofa A0A286ZN93 R-SSC-9853389 https://reactome.org/PathwayBrowser/#/R-SSC-9853389 FIGNL1 binds RAD51 IEA Sus scrofa A0A286ZN96 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A286ZN96 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A286ZN96 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A286ZN96 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A286ZNB3 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A286ZNB3 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A286ZNB3 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A286ZNB3 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A286ZNB3 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A286ZND1 R-SSC-418091 https://reactome.org/PathwayBrowser/#/R-SSC-418091 F2R binds ARRB1 IEA Sus scrofa A0A286ZND1 R-SSC-418158 https://reactome.org/PathwayBrowser/#/R-SSC-418158 SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) IEA Sus scrofa A0A286ZND1 R-SSC-418163 https://reactome.org/PathwayBrowser/#/R-SSC-418163 Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) IEA Sus scrofa A0A286ZND1 R-SSC-418170 https://reactome.org/PathwayBrowser/#/R-SSC-418170 F2R:ARRB1 binds MAPKs, SRC-1 IEA Sus scrofa A0A286ZND1 R-SSC-421831 https://reactome.org/PathwayBrowser/#/R-SSC-421831 trans-Golgi Network Coat Assembly IEA Sus scrofa A0A286ZND1 R-SSC-421835 https://reactome.org/PathwayBrowser/#/R-SSC-421835 trans-Golgi Network Vesicle Scission IEA Sus scrofa A0A286ZND1 R-SSC-432706 https://reactome.org/PathwayBrowser/#/R-SSC-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Sus scrofa A0A286ZND1 R-SSC-432707 https://reactome.org/PathwayBrowser/#/R-SSC-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Sus scrofa A0A286ZND1 R-SSC-5632668 https://reactome.org/PathwayBrowser/#/R-SSC-5632668 SMO translocates to the cilium IEA Sus scrofa A0A286ZND1 R-SSC-5672972 https://reactome.org/PathwayBrowser/#/R-SSC-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Sus scrofa A0A286ZND1 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa A0A286ZND1 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa A0A286ZND1 R-SSC-5672980 https://reactome.org/PathwayBrowser/#/R-SSC-5672980 Dissociation of RAS:RAF complex IEA Sus scrofa A0A286ZND1 R-SSC-5696945 https://reactome.org/PathwayBrowser/#/R-SSC-5696945 USP33 deubiquitinates CCP110,ARRB IEA Sus scrofa A0A286ZND1 R-SSC-8852167 https://reactome.org/PathwayBrowser/#/R-SSC-8852167 ADRB2:Catecholamine binds ARRB1, ARRB2 IEA Sus scrofa A0A286ZND1 R-SSC-8866269 https://reactome.org/PathwayBrowser/#/R-SSC-8866269 ARRB bind GPCRs IEA Sus scrofa A0A286ZND1 R-SSC-8866283 https://reactome.org/PathwayBrowser/#/R-SSC-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Sus scrofa A0A286ZND1 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A286ZND1 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A286ZND1 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A286ZND1 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A286ZND1 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A286ZND1 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A286ZND1 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A286ZND1 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A286ZND1 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A286ZND1 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A286ZND1 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A286ZND1 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A286ZND1 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A286ZND1 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A286ZND1 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa A0A286ZND1 R-SSC-9657603 https://reactome.org/PathwayBrowser/#/R-SSC-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Sus scrofa A0A286ZND1 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa A0A286ZND1 R-SSC-9657608 https://reactome.org/PathwayBrowser/#/R-SSC-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Sus scrofa A0A286ZND1 R-SSC-9839358 https://reactome.org/PathwayBrowser/#/R-SSC-9839358 Endocytosis of TGFBR3:ARRB complex IEA Sus scrofa A0A286ZND1 R-SSC-9839378 https://reactome.org/PathwayBrowser/#/R-SSC-9839378 TGFBR3 binding to ARRB1/2 IEA Sus scrofa A0A286ZND2 R-SSC-9606884 https://reactome.org/PathwayBrowser/#/R-SSC-9606884 PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated IEA Sus scrofa A0A286ZND2 R-SSC-9606894 https://reactome.org/PathwayBrowser/#/R-SSC-9606894 p-DAPP1 (p-BAM32) binds PLCG2 IEA Sus scrofa A0A286ZND5 R-SSC-3341343 https://reactome.org/PathwayBrowser/#/R-SSC-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Sus scrofa A0A286ZND5 R-SSC-5631885 https://reactome.org/PathwayBrowser/#/R-SSC-5631885 PRDX1 overoxidizes IEA Sus scrofa A0A286ZND5 R-SSC-5631903 https://reactome.org/PathwayBrowser/#/R-SSC-5631903 SESN1,2,3 bind overoxidized PRDX1 IEA Sus scrofa A0A286ZND5 R-SSC-9760094 https://reactome.org/PathwayBrowser/#/R-SSC-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Sus scrofa A0A286ZND9 R-SSC-182594 https://reactome.org/PathwayBrowser/#/R-SSC-182594 Association of INK4 family proteins with CDK4/6 IEA Sus scrofa A0A286ZND9 R-SSC-8941895 https://reactome.org/PathwayBrowser/#/R-SSC-8941895 Formation of CDK4/6:CCND complexes IEA Sus scrofa A0A286ZNE7 R-SSC-191402 https://reactome.org/PathwayBrowser/#/R-SSC-191402 Reduction of presqualene diphosphate to form squalene IEA Sus scrofa A0A286ZNE7 R-SSC-191405 https://reactome.org/PathwayBrowser/#/R-SSC-191405 Two FPP molecules dimerize to form presqualene diphosphate IEA Sus scrofa A0A286ZNF3 R-SSC-109530 https://reactome.org/PathwayBrowser/#/R-SSC-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Sus scrofa A0A286ZNF5 R-SSC-201422 https://reactome.org/PathwayBrowser/#/R-SSC-201422 Phospho-R-Smad1/5/8 forms a complex with Co-Smad IEA Sus scrofa A0A286ZNF5 R-SSC-201423 https://reactome.org/PathwayBrowser/#/R-SSC-201423 SKI complexes with the Smad complex, suppressing BMP2 signalling IEA Sus scrofa A0A286ZNF5 R-SSC-201425 https://reactome.org/PathwayBrowser/#/R-SSC-201425 Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling IEA Sus scrofa A0A286ZNF5 R-SSC-201445 https://reactome.org/PathwayBrowser/#/R-SSC-201445 Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8 IEA Sus scrofa A0A286ZNF5 R-SSC-201453 https://reactome.org/PathwayBrowser/#/R-SSC-201453 Phospho-R-Smad1/5/8 dissociates from the receptor complex IEA Sus scrofa A0A286ZNF5 R-SSC-201472 https://reactome.org/PathwayBrowser/#/R-SSC-201472 The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus IEA Sus scrofa A0A286ZNF5 R-SSC-201476 https://reactome.org/PathwayBrowser/#/R-SSC-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Sus scrofa A0A286ZNF5 R-SSC-201648 https://reactome.org/PathwayBrowser/#/R-SSC-201648 An anchoring protein, Endofin, recruits R-Smad1/5/8 IEA Sus scrofa A0A286ZNF5 R-SSC-202626 https://reactome.org/PathwayBrowser/#/R-SSC-202626 I-Smad competes with Co-Smad for R-Smad1/5/8 IEA Sus scrofa A0A286ZNG5 R-SSC-425577 https://reactome.org/PathwayBrowser/#/R-SSC-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Sus scrofa A0A286ZNH3 R-SSC-9014641 https://reactome.org/PathwayBrowser/#/R-SSC-9014641 HRSP12 deaminates 2-iminobutanoate to 2OBUTA IEA Sus scrofa A0A286ZNK2 R-SSC-8850594 https://reactome.org/PathwayBrowser/#/R-SSC-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Sus scrofa A0A286ZNK2 R-SSC-8866542 https://reactome.org/PathwayBrowser/#/R-SSC-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Sus scrofa A0A286ZNK2 R-SSC-8866546 https://reactome.org/PathwayBrowser/#/R-SSC-8866546 RNF5 and RNF185 ubiquitinate misfolded CFTR IEA Sus scrofa A0A286ZNK2 R-SSC-8866551 https://reactome.org/PathwayBrowser/#/R-SSC-8866551 CFTR binds components of the ERAD machinery for ubiquitination and degradation IEA Sus scrofa A0A286ZNK4 R-SSC-1254248 https://reactome.org/PathwayBrowser/#/R-SSC-1254248 Translocation of ERBB4s80:YAP1 complex to the nucleus IEA Sus scrofa A0A286ZNK4 R-SSC-1254251 https://reactome.org/PathwayBrowser/#/R-SSC-1254251 ERBB4s80 binds YAP1 IEA Sus scrofa A0A286ZNK4 R-SSC-2028583 https://reactome.org/PathwayBrowser/#/R-SSC-2028583 Phosphorylation of YAP by LATS2 IEA Sus scrofa A0A286ZNK4 R-SSC-2028598 https://reactome.org/PathwayBrowser/#/R-SSC-2028598 Phosphorylation of YAP by LATS1 IEA Sus scrofa A0A286ZNK4 R-SSC-2028644 https://reactome.org/PathwayBrowser/#/R-SSC-2028644 YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 IEA Sus scrofa A0A286ZNK4 R-SSC-2028724 https://reactome.org/PathwayBrowser/#/R-SSC-2028724 AMOT proteins bind YAP1 IEA Sus scrofa A0A286ZNK4 R-SSC-2032770 https://reactome.org/PathwayBrowser/#/R-SSC-2032770 Translocation of YAP1 to the nucleus IEA Sus scrofa A0A286ZNK4 R-SSC-2032775 https://reactome.org/PathwayBrowser/#/R-SSC-2032775 YAP1 binds TEAD1 IEA Sus scrofa A0A286ZNK4 R-SSC-2064406 https://reactome.org/PathwayBrowser/#/R-SSC-2064406 Translocation of YAP1:ZO-2 (TJP2) to the nucleus IEA Sus scrofa A0A286ZNK4 R-SSC-2064421 https://reactome.org/PathwayBrowser/#/R-SSC-2064421 YAP1 binds ZO-2 (TJP2) IEA Sus scrofa A0A286ZNK4 R-SSC-8871260 https://reactome.org/PathwayBrowser/#/R-SSC-8871260 YAP1 binds TEAD2 IEA Sus scrofa A0A286ZNK4 R-SSC-8871265 https://reactome.org/PathwayBrowser/#/R-SSC-8871265 YAP1 binds TEAD4 IEA Sus scrofa A0A286ZNK4 R-SSC-8871266 https://reactome.org/PathwayBrowser/#/R-SSC-8871266 YAP1 binds TEAD3 IEA Sus scrofa A0A286ZNK4 R-SSC-8951676 https://reactome.org/PathwayBrowser/#/R-SSC-8951676 RUNX3 binds TEADs and YAP1 IEA Sus scrofa A0A286ZNK4 R-SSC-8956639 https://reactome.org/PathwayBrowser/#/R-SSC-8956639 RUNX1 binds YAP1 IEA Sus scrofa A0A286ZNK4 R-SSC-8956659 https://reactome.org/PathwayBrowser/#/R-SSC-8956659 ABL1 phosphorylates YAP1 IEA Sus scrofa A0A286ZNK4 R-SSC-8956676 https://reactome.org/PathwayBrowser/#/R-SSC-8956676 YAP1 binds TP73 IEA Sus scrofa A0A286ZNK4 R-SSC-9865176 https://reactome.org/PathwayBrowser/#/R-SSC-9865176 p-Y407-YAP1 translocates from the cytosol to the nucleoplasm IEA Sus scrofa A0A286ZNK4 R-SSC-9865196 https://reactome.org/PathwayBrowser/#/R-SSC-9865196 p-Y393-ABL1 phosphorylates tyrosine-407 of YAP1 IEA Sus scrofa A0A286ZNK4 R-SSC-9865226 https://reactome.org/PathwayBrowser/#/R-SSC-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Sus scrofa A0A286ZNK5 R-SSC-5696491 https://reactome.org/PathwayBrowser/#/R-SSC-5696491 CNTF binds CNTFR complex IEA Sus scrofa A0A286ZNK5 R-SSC-6783530 https://reactome.org/PathwayBrowser/#/R-SSC-6783530 gp130:JAKs bind CNTFR IEA Sus scrofa A0A286ZNK5 R-SSC-6783556 https://reactome.org/PathwayBrowser/#/R-SSC-6783556 LIFR:JAKs bind gp130:JAKs:CNTFR IEA Sus scrofa A0A286ZNM1 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A286ZNM1 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A286ZNM1 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A286ZNN4 R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Sus scrofa A0A286ZNN4 R-SSC-6799179 https://reactome.org/PathwayBrowser/#/R-SSC-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Sus scrofa A0A286ZNN4 R-SSC-6799191 https://reactome.org/PathwayBrowser/#/R-SSC-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Sus scrofa A0A286ZNN4 R-SSC-6799196 https://reactome.org/PathwayBrowser/#/R-SSC-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Sus scrofa A0A286ZNN4 R-SSC-6799202 https://reactome.org/PathwayBrowser/#/R-SSC-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Sus scrofa A0A286ZNN4 R-SSC-6799203 https://reactome.org/PathwayBrowser/#/R-SSC-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Sus scrofa A0A286ZNN4 R-SSC-6800868 https://reactome.org/PathwayBrowser/#/R-SSC-6800868 NDUF subunits bind to form the IP subcomplex IEA Sus scrofa A0A286ZNN4 R-SSC-9014449 https://reactome.org/PathwayBrowser/#/R-SSC-9014449 RHOG binds effectors at the plasma membrane IEA Sus scrofa A0A286ZNN4 R-SSC-9838035 https://reactome.org/PathwayBrowser/#/R-SSC-9838035 CLPXP binds mitochondrial matrix proteins IEA Sus scrofa A0A286ZNN4 R-SSC-9838289 https://reactome.org/PathwayBrowser/#/R-SSC-9838289 CLPXP degrades mitochondrial matrix proteins IEA Sus scrofa A0A286ZNS2 R-SSC-9012268 https://reactome.org/PathwayBrowser/#/R-SSC-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Sus scrofa A0A286ZNS2 R-SSC-9838035 https://reactome.org/PathwayBrowser/#/R-SSC-9838035 CLPXP binds mitochondrial matrix proteins IEA Sus scrofa A0A286ZNS2 R-SSC-9838081 https://reactome.org/PathwayBrowser/#/R-SSC-9838081 LONP1 degrades mitochondrial matrix proteins IEA Sus scrofa A0A286ZNS2 R-SSC-9838093 https://reactome.org/PathwayBrowser/#/R-SSC-9838093 LONP1 binds mitochondrial matrix proteins IEA Sus scrofa A0A286ZNS2 R-SSC-9838289 https://reactome.org/PathwayBrowser/#/R-SSC-9838289 CLPXP degrades mitochondrial matrix proteins IEA Sus scrofa A0A286ZNU0 R-SSC-110360 https://reactome.org/PathwayBrowser/#/R-SSC-110360 Recruitment of POLB to the AP site IEA Sus scrofa A0A286ZNU0 R-SSC-110364 https://reactome.org/PathwayBrowser/#/R-SSC-110364 PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 IEA Sus scrofa A0A286ZNU0 R-SSC-110375 https://reactome.org/PathwayBrowser/#/R-SSC-110375 Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break IEA Sus scrofa A0A286ZNU0 R-SSC-110376 https://reactome.org/PathwayBrowser/#/R-SSC-110376 Recruitment of LIG3:XRCC1 complex to the site of repair by POLB IEA Sus scrofa A0A286ZNU0 R-SSC-111253 https://reactome.org/PathwayBrowser/#/R-SSC-111253 POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site IEA Sus scrofa A0A286ZNU0 R-SSC-5649705 https://reactome.org/PathwayBrowser/#/R-SSC-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Sus scrofa A0A286ZNU0 R-SSC-5649708 https://reactome.org/PathwayBrowser/#/R-SSC-5649708 NEIL1,NEIL2 recruits POLB to incised AP site IEA Sus scrofa A0A286ZNU0 R-SSC-5649723 https://reactome.org/PathwayBrowser/#/R-SSC-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Sus scrofa A0A286ZNU0 R-SSC-5649725 https://reactome.org/PathwayBrowser/#/R-SSC-5649725 POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) IEA Sus scrofa A0A286ZNU0 R-SSC-5649726 https://reactome.org/PathwayBrowser/#/R-SSC-5649726 LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA IEA Sus scrofa A0A286ZNU0 R-SSC-5649734 https://reactome.org/PathwayBrowser/#/R-SSC-5649734 LIG3 ligates NEIL1,NEIL2-generated single strand break IEA Sus scrofa A0A286ZNU0 R-SSC-5649854 https://reactome.org/PathwayBrowser/#/R-SSC-5649854 Recruitment of POLB to oxidatively damaged AP site IEA Sus scrofa A0A286ZNU0 R-SSC-5649873 https://reactome.org/PathwayBrowser/#/R-SSC-5649873 PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site IEA Sus scrofa A0A286ZNU0 R-SSC-5649883 https://reactome.org/PathwayBrowser/#/R-SSC-5649883 POLB-mediated DNA strand displacement synthesis IEA Sus scrofa A0A286ZNU0 R-SSC-5651723 https://reactome.org/PathwayBrowser/#/R-SSC-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Sus scrofa A0A286ZNU0 R-SSC-5651739 https://reactome.org/PathwayBrowser/#/R-SSC-5651739 PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB IEA Sus scrofa A0A286ZNU0 R-SSC-5651773 https://reactome.org/PathwayBrowser/#/R-SSC-5651773 LIG1 binds POLB at long-patch BER site IEA Sus scrofa A0A286ZNU0 R-SSC-5651789 https://reactome.org/PathwayBrowser/#/R-SSC-5651789 LIG1 bound to POLB ligates SSB IEA Sus scrofa A0A286ZNU0 R-SSC-5696947 https://reactome.org/PathwayBrowser/#/R-SSC-5696947 USP47 deubiquitinates POLB IEA Sus scrofa A0A286ZNU0 R-SSC-73931 https://reactome.org/PathwayBrowser/#/R-SSC-73931 LIG3-mediated DNA ligation via the single-nucleotide replacement pathway IEA Sus scrofa A0A286ZNU0 R-SSC-73932 https://reactome.org/PathwayBrowser/#/R-SSC-73932 Resynthesis of excised residue by POLB IEA Sus scrofa A0A286ZNU9 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZNU9 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A286ZNU9 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZNU9 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A286ZNW2 R-SSC-914010 https://reactome.org/PathwayBrowser/#/R-SSC-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Sus scrofa A0A286ZNW5 R-SSC-1889981 https://reactome.org/PathwayBrowser/#/R-SSC-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Sus scrofa A0A286ZP06 R-SSC-210420 https://reactome.org/PathwayBrowser/#/R-SSC-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Sus scrofa A0A286ZP06 R-SSC-265645 https://reactome.org/PathwayBrowser/#/R-SSC-265645 Calcium Influx through Voltage-gated Calcium Channels IEA Sus scrofa A0A286ZP19 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A286ZP27 R-SSC-6805546 https://reactome.org/PathwayBrowser/#/R-SSC-6805546 Keratin type I binds keratin type II IEA Sus scrofa A0A286ZP27 R-SSC-6805573 https://reactome.org/PathwayBrowser/#/R-SSC-6805573 Keratin type I/type II heterodimers form tetramers IEA Sus scrofa A0A286ZP27 R-SSC-6806610 https://reactome.org/PathwayBrowser/#/R-SSC-6806610 Keratin filament formation IEA Sus scrofa A0A286ZP27 R-SSC-6806613 https://reactome.org/PathwayBrowser/#/R-SSC-6806613 Keratin tetramers bind to form unit length filaments IEA Sus scrofa A0A286ZP27 R-SSC-6806629 https://reactome.org/PathwayBrowser/#/R-SSC-6806629 Formation of tonofilament bundles IEA Sus scrofa A0A286ZP27 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A286ZP27 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A286ZP27 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A286ZP27 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A286ZP33 R-SSC-1861595 https://reactome.org/PathwayBrowser/#/R-SSC-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Sus scrofa A0A286ZP33 R-SSC-2029466 https://reactome.org/PathwayBrowser/#/R-SSC-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Sus scrofa A0A286ZP33 R-SSC-2029473 https://reactome.org/PathwayBrowser/#/R-SSC-2029473 Branching and elongation of mother and daughter filaments IEA Sus scrofa A0A286ZP33 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A286ZP33 R-SSC-2197690 https://reactome.org/PathwayBrowser/#/R-SSC-2197690 Detachment of WASP/WAVE IEA Sus scrofa A0A286ZP33 R-SSC-3928595 https://reactome.org/PathwayBrowser/#/R-SSC-3928595 N-WASP binds ARP2/3 and G-actin IEA Sus scrofa A0A286ZP42 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A286ZP42 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A286ZP42 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A286ZP42 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A286ZP42 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A286ZP42 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A286ZP42 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A286ZP42 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A286ZP42 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A286ZP42 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZP42 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A286ZP42 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A286ZP42 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A286ZP42 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A286ZP42 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A286ZP42 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A286ZP42 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A286ZP42 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A286ZP42 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A286ZP42 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A286ZP42 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A286ZP42 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A286ZP42 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A286ZP42 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A286ZP42 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A286ZP42 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A286ZP42 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A286ZP42 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A286ZP42 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A286ZP42 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A286ZP42 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A286ZP42 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A286ZP42 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A286ZP42 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A286ZP42 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A286ZP42 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A286ZP42 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A286ZP42 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A286ZP42 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A286ZP42 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A286ZP42 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A286ZP42 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A286ZP42 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A286ZP42 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A286ZP42 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A286ZP42 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A286ZP42 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A286ZP49 R-SSC-418582 https://reactome.org/PathwayBrowser/#/R-SSC-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Sus scrofa A0A286ZP49 R-SSC-8982012 https://reactome.org/PathwayBrowser/#/R-SSC-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Sus scrofa A0A286ZP49 R-SSC-8982017 https://reactome.org/PathwayBrowser/#/R-SSC-8982017 Active G alpha (q) binds RGS proteins IEA Sus scrofa A0A286ZP49 R-SSC-8982019 https://reactome.org/PathwayBrowser/#/R-SSC-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Sus scrofa A0A286ZP49 R-SSC-8982020 https://reactome.org/PathwayBrowser/#/R-SSC-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Sus scrofa A0A286ZP49 R-SSC-8982025 https://reactome.org/PathwayBrowser/#/R-SSC-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Sus scrofa A0A286ZP49 R-SSC-8982026 https://reactome.org/PathwayBrowser/#/R-SSC-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Sus scrofa A0A286ZP52 R-SSC-210420 https://reactome.org/PathwayBrowser/#/R-SSC-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Sus scrofa A0A286ZP52 R-SSC-265645 https://reactome.org/PathwayBrowser/#/R-SSC-265645 Calcium Influx through Voltage-gated Calcium Channels IEA Sus scrofa A0A286ZP52 R-SSC-5577213 https://reactome.org/PathwayBrowser/#/R-SSC-5577213 LTCC multimer transports Ca2+ from extracellular region to cytosol IEA Sus scrofa A0A286ZP52 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa A0A286ZP53 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A286ZP53 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa A0A286ZP53 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa A0A286ZP53 R-SSC-983259 https://reactome.org/PathwayBrowser/#/R-SSC-983259 Kinesins move along microtubules consuming ATP IEA Sus scrofa A0A286ZP53 R-SSC-983266 https://reactome.org/PathwayBrowser/#/R-SSC-983266 Kinesins bind microtubules IEA Sus scrofa A0A286ZP67 R-SSC-72103 https://reactome.org/PathwayBrowser/#/R-SSC-72103 Formation of pre-mRNPs IEA Sus scrofa A0A286ZP67 R-SSC-9770119 https://reactome.org/PathwayBrowser/#/R-SSC-9770119 Formation of the Spliceosomal E complex IEA Sus scrofa A0A286ZP67 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A286ZP67 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A286ZP67 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A286ZP67 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A286ZP73 R-SSC-5250930 https://reactome.org/PathwayBrowser/#/R-SSC-5250930 B-WICH recruits histone acetyltransferases IEA Sus scrofa A0A286ZP73 R-SSC-5250938 https://reactome.org/PathwayBrowser/#/R-SSC-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Sus scrofa A0A286ZP73 R-SSC-606287 https://reactome.org/PathwayBrowser/#/R-SSC-606287 RSF complex binds the centromere IEA Sus scrofa A0A286ZPA0 R-SSC-5696183 https://reactome.org/PathwayBrowser/#/R-SSC-5696183 AOC3 deaminates BZAM IEA Sus scrofa A0A286ZPA2 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A286ZPA2 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A286ZPA2 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A286ZPA2 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A286ZPA2 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A286ZPA2 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A286ZPA2 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A286ZPA2 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A286ZPA2 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A286ZPA2 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A286ZPA2 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A286ZPA2 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A286ZPA2 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A286ZPA2 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A286ZPA2 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A286ZPA2 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A286ZPA2 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A286ZPA2 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A286ZPA2 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A286ZPA2 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A286ZPA2 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A286ZPA2 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A286ZPA2 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A286ZPA2 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A286ZPA2 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A286ZPA2 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A286ZPA2 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A286ZPA2 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A286ZPA2 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A286ZPA2 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A286ZPA2 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A286ZPA2 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A286ZPA2 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A286ZPA2 R-SSC-8852298 https://reactome.org/PathwayBrowser/#/R-SSC-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends IEA Sus scrofa A0A286ZPA2 R-SSC-8852306 https://reactome.org/PathwayBrowser/#/R-SSC-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Sus scrofa A0A286ZPA2 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A286ZPA2 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A286ZPA2 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A286ZPB0 R-SSC-1602399 https://reactome.org/PathwayBrowser/#/R-SSC-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Sus scrofa A0A286ZPB0 R-SSC-975594 https://reactome.org/PathwayBrowser/#/R-SSC-975594 PLB1 hydrolyses RPALM to atROL IEA Sus scrofa A0A286ZPB3 R-SSC-429955 https://reactome.org/PathwayBrowser/#/R-SSC-429955 CCR4-NOT complex deadenylates mRNA IEA Sus scrofa A0A286ZPB3 R-SSC-6798044 https://reactome.org/PathwayBrowser/#/R-SSC-6798044 BTG2 binds CCR4-NOT complex IEA Sus scrofa A0A286ZPB7 R-SSC-5690157 https://reactome.org/PathwayBrowser/#/R-SSC-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Sus scrofa A0A286ZPD0 R-SSC-9938195 https://reactome.org/PathwayBrowser/#/R-SSC-9938195 SLC25A51 mediates mitochondrial uptake of NAD+ IEA Sus scrofa A0A286ZPE3 R-SSC-6803523 https://reactome.org/PathwayBrowser/#/R-SSC-6803523 PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA IEA Sus scrofa A0A286ZPE3 R-SSC-72103 https://reactome.org/PathwayBrowser/#/R-SSC-72103 Formation of pre-mRNPs IEA Sus scrofa A0A286ZPE3 R-SSC-9770119 https://reactome.org/PathwayBrowser/#/R-SSC-9770119 Formation of the Spliceosomal E complex IEA Sus scrofa A0A286ZPE3 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A286ZPE3 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A286ZPE3 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A286ZPE3 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A286ZPF4 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa A0A286ZPF4 R-SSC-420123 https://reactome.org/PathwayBrowser/#/R-SSC-420123 Glucagon-like receptor 2 binds GLP2 IEA Sus scrofa A0A286ZPG1 R-SSC-3247837 https://reactome.org/PathwayBrowser/#/R-SSC-3247837 WNT ligands traffic to the Golgi IEA Sus scrofa A0A286ZPG1 R-SSC-3247840 https://reactome.org/PathwayBrowser/#/R-SSC-3247840 WLS binds WNT ligands in the Golgi IEA Sus scrofa A0A286ZPG1 R-SSC-3247843 https://reactome.org/PathwayBrowser/#/R-SSC-3247843 secretion of WNT ligands IEA Sus scrofa A0A286ZPG1 R-SSC-3247844 https://reactome.org/PathwayBrowser/#/R-SSC-3247844 WNT ligands traffic to the plasma membrane IEA Sus scrofa A0A286ZPG1 R-SSC-3781941 https://reactome.org/PathwayBrowser/#/R-SSC-3781941 WNTs are secreted in exosomes IEA Sus scrofa A0A286ZPG1 R-SSC-3781943 https://reactome.org/PathwayBrowser/#/R-SSC-3781943 WLS:WNT complex is internalized for maturation into exosomes IEA Sus scrofa A0A286ZPG1 R-SSC-3858482 https://reactome.org/PathwayBrowser/#/R-SSC-3858482 DVL is recruited to the receptor IEA Sus scrofa A0A286ZPH0 R-SSC-201810 https://reactome.org/PathwayBrowser/#/R-SSC-201810 The ligand trap binds the ligand BMP2, blocking BMP signalling IEA Sus scrofa A0A286ZPI2 R-SSC-5676607 https://reactome.org/PathwayBrowser/#/R-SSC-5676607 sBAFF,sAPRIL binds TACI,BCMA IEA Sus scrofa A0A286ZPI9 R-SSC-8858298 https://reactome.org/PathwayBrowser/#/R-SSC-8858298 HRASLS transfer acyl group from PC to PE to form NAPE IEA Sus scrofa A0A286ZPJ7 R-SSC-5223305 https://reactome.org/PathwayBrowser/#/R-SSC-5223305 ABCE1 binds RNASEL, inhibiting it IEA Sus scrofa A0A286ZPJ7 R-SSC-8985201 https://reactome.org/PathwayBrowser/#/R-SSC-8985201 ABCE1 binds RNASEL IEA Sus scrofa A0A286ZPJ7 R-SSC-9009936 https://reactome.org/PathwayBrowser/#/R-SSC-9009936 RNASEL cleaves cellular ssRNA IEA Sus scrofa A0A286ZPK0 R-SSC-453200 https://reactome.org/PathwayBrowser/#/R-SSC-453200 SYK autophosphorylates IEA Sus scrofa A0A286ZPK0 R-SSC-5684169 https://reactome.org/PathwayBrowser/#/R-SSC-5684169 G6B binds PTPN6,PTPN11 IEA Sus scrofa A0A286ZPK0 R-SSC-5684801 https://reactome.org/PathwayBrowser/#/R-SSC-5684801 p-Y7-CLEC1B dimer:PDPN binds SYK IEA Sus scrofa A0A286ZPK2 R-SSC-202248 https://reactome.org/PathwayBrowser/#/R-SSC-202248 Phosphorylation of PLC-gamma1 IEA Sus scrofa A0A286ZPK2 R-SSC-202375 https://reactome.org/PathwayBrowser/#/R-SSC-202375 Recruitment of ITK to SLP-76 IEA Sus scrofa A0A286ZPK2 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A286ZPK2 R-SSC-2730847 https://reactome.org/PathwayBrowser/#/R-SSC-2730847 Hydrolysis of PIP2 by PLCG IEA Sus scrofa A0A286ZPK2 R-SSC-2730858 https://reactome.org/PathwayBrowser/#/R-SSC-2730858 Autophosphorylation of BTK/ITK IEA Sus scrofa A0A286ZPL4 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A286ZPL4 R-SSC-380076 https://reactome.org/PathwayBrowser/#/R-SSC-380076 Tachykinin receptor 1 (NK1) binds to substance P IEA Sus scrofa A0A286ZPL4 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A286ZPL4 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A286ZPL4 R-SSC-8866269 https://reactome.org/PathwayBrowser/#/R-SSC-8866269 ARRB bind GPCRs IEA Sus scrofa A0A286ZPL4 R-SSC-8866283 https://reactome.org/PathwayBrowser/#/R-SSC-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Sus scrofa A0A286ZPL4 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A286ZPL4 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A286ZPL4 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A286ZPL4 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A286ZPL4 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A286ZPL4 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A286ZPL4 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A286ZPL4 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A286ZPL4 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A286ZPL4 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A286ZPL4 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A286ZPL4 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A286ZPL4 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A286ZPL4 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A286ZPM4 R-SSC-183002 https://reactome.org/PathwayBrowser/#/R-SSC-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Sus scrofa A0A286ZPM4 R-SSC-183084 https://reactome.org/PathwayBrowser/#/R-SSC-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Sus scrofa A0A286ZPM4 R-SSC-183094 https://reactome.org/PathwayBrowser/#/R-SSC-183094 CDC42:GTP binds CBL:Beta-Pix IEA Sus scrofa A0A286ZPM4 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa A0A286ZPM4 R-SSC-3928625 https://reactome.org/PathwayBrowser/#/R-SSC-3928625 PAKs autophosphorylate IEA Sus scrofa A0A286ZPM4 R-SSC-3928631 https://reactome.org/PathwayBrowser/#/R-SSC-3928631 GIT1 binds bPIX IEA Sus scrofa A0A286ZPM4 R-SSC-3928633 https://reactome.org/PathwayBrowser/#/R-SSC-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Sus scrofa A0A286ZPM4 R-SSC-3928640 https://reactome.org/PathwayBrowser/#/R-SSC-3928640 PAKs phosphorylate MLC IEA Sus scrofa A0A286ZPM4 R-SSC-3928641 https://reactome.org/PathwayBrowser/#/R-SSC-3928641 PAK binds RAC and bPIX IEA Sus scrofa A0A286ZPM4 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa A0A286ZPM4 R-SSC-8951490 https://reactome.org/PathwayBrowser/#/R-SSC-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Sus scrofa A0A286ZPM4 R-SSC-8980691 https://reactome.org/PathwayBrowser/#/R-SSC-8980691 RHOA GEFs activate RHOA IEA Sus scrofa A0A286ZPM4 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A286ZPM4 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZPM4 R-SSC-9018746 https://reactome.org/PathwayBrowser/#/R-SSC-9018746 RHOQ binds effectors at the plasma membrane IEA Sus scrofa A0A286ZPM4 R-SSC-9018766 https://reactome.org/PathwayBrowser/#/R-SSC-9018766 RHOU binds effectors at the plasma membrane IEA Sus scrofa A0A286ZPM4 R-SSC-9018794 https://reactome.org/PathwayBrowser/#/R-SSC-9018794 RHOV binds effectors at the plasma membrane IEA Sus scrofa A0A286ZPP2 R-SSC-2213192 https://reactome.org/PathwayBrowser/#/R-SSC-2213192 Hemidesmosome formation IEA Sus scrofa A0A286ZPP2 R-SSC-432956 https://reactome.org/PathwayBrowser/#/R-SSC-432956 BP230 is recruited to the hemidesmosome IEA Sus scrofa A0A286ZPP2 R-SSC-446077 https://reactome.org/PathwayBrowser/#/R-SSC-446077 BP230 interacts with keretin K5/K14 IEA Sus scrofa A0A286ZPP2 R-SSC-446083 https://reactome.org/PathwayBrowser/#/R-SSC-446083 CD151 interacts with BP180 and the integrin alpha 6 subunit IEA Sus scrofa A0A286ZPP2 R-SSC-9018766 https://reactome.org/PathwayBrowser/#/R-SSC-9018766 RHOU binds effectors at the plasma membrane IEA Sus scrofa A0A286ZPP2 R-SSC-9018794 https://reactome.org/PathwayBrowser/#/R-SSC-9018794 RHOV binds effectors at the plasma membrane IEA Sus scrofa A0A286ZPP2 R-SSC-9696266 https://reactome.org/PathwayBrowser/#/R-SSC-9696266 RND2 binds effectors IEA Sus scrofa A0A286ZPP2 R-SSC-9696268 https://reactome.org/PathwayBrowser/#/R-SSC-9696268 RND3 binds effectors IEA Sus scrofa A0A286ZPP2 R-SSC-9696271 https://reactome.org/PathwayBrowser/#/R-SSC-9696271 RND1 binds effectors IEA Sus scrofa A0A286ZPP9 R-SSC-8854173 https://reactome.org/PathwayBrowser/#/R-SSC-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Sus scrofa A0A286ZPQ2 R-SSC-8875318 https://reactome.org/PathwayBrowser/#/R-SSC-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Sus scrofa A0A286ZPQ2 R-SSC-8875320 https://reactome.org/PathwayBrowser/#/R-SSC-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Sus scrofa A0A286ZPQ2 R-SSC-8876188 https://reactome.org/PathwayBrowser/#/R-SSC-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Sus scrofa A0A286ZPQ2 R-SSC-8876190 https://reactome.org/PathwayBrowser/#/R-SSC-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Sus scrofa A0A286ZPQ2 R-SSC-8876191 https://reactome.org/PathwayBrowser/#/R-SSC-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Sus scrofa A0A286ZPQ2 R-SSC-8876454 https://reactome.org/PathwayBrowser/#/R-SSC-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Sus scrofa A0A286ZPQ2 R-SSC-8876615 https://reactome.org/PathwayBrowser/#/R-SSC-8876615 RAB13 GEFs exchange GTP for GDP on RAB13 IEA Sus scrofa A0A286ZPQ2 R-SSC-8877308 https://reactome.org/PathwayBrowser/#/R-SSC-8877308 MADD exchanges GTP for GDP on RAB27 IEA Sus scrofa A0A286ZPQ2 R-SSC-8877311 https://reactome.org/PathwayBrowser/#/R-SSC-8877311 RAB31 GEFs exchange GTP for GDP on RAB31 IEA Sus scrofa A0A286ZPQ2 R-SSC-8877451 https://reactome.org/PathwayBrowser/#/R-SSC-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Sus scrofa A0A286ZPQ2 R-SSC-8877612 https://reactome.org/PathwayBrowser/#/R-SSC-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Sus scrofa A0A286ZPQ2 R-SSC-8877760 https://reactome.org/PathwayBrowser/#/R-SSC-8877760 HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 IEA Sus scrofa A0A286ZPQ2 R-SSC-8877813 https://reactome.org/PathwayBrowser/#/R-SSC-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Sus scrofa A0A286ZPQ2 R-SSC-8877998 https://reactome.org/PathwayBrowser/#/R-SSC-8877998 RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 IEA Sus scrofa A0A286ZPQ4 R-SSC-8876188 https://reactome.org/PathwayBrowser/#/R-SSC-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Sus scrofa A0A286ZPR8 R-SSC-164651 https://reactome.org/PathwayBrowser/#/R-SSC-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Sus scrofa A0A286ZPR8 R-SSC-9906042 https://reactome.org/PathwayBrowser/#/R-SSC-9906042 TTC19 clears UQCRFS1 fragments from Complex III IEA Sus scrofa A0A286ZPT0 R-SSC-6807872 https://reactome.org/PathwayBrowser/#/R-SSC-6807872 Active ARF recruits coatomer IEA Sus scrofa A0A286ZPT0 R-SSC-6807875 https://reactome.org/PathwayBrowser/#/R-SSC-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Sus scrofa A0A286ZPT0 R-SSC-6807877 https://reactome.org/PathwayBrowser/#/R-SSC-6807877 ARFGAPs stimulate ARF GTPase activity IEA Sus scrofa A0A286ZPT0 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa A0A286ZPT0 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A286ZPT0 R-SSC-6809011 https://reactome.org/PathwayBrowser/#/R-SSC-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Sus scrofa A0A286ZPT0 R-SSC-6811417 https://reactome.org/PathwayBrowser/#/R-SSC-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Sus scrofa A0A286ZPT0 R-SSC-6811418 https://reactome.org/PathwayBrowser/#/R-SSC-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Sus scrofa A0A286ZPT0 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa A0A286ZPT0 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa A0A286ZPT1 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A286ZPT1 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A286ZPT1 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A286ZPT1 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A286ZPT1 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A286ZPT1 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A286ZPT1 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A286ZPT1 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A286ZPT1 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A286ZPT1 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A286ZPT1 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A286ZPT3 R-SSC-8847534 https://reactome.org/PathwayBrowser/#/R-SSC-8847534 RAB43 hydrolyses GTP IEA Sus scrofa A0A286ZPT3 R-SSC-8847537 https://reactome.org/PathwayBrowser/#/R-SSC-8847537 RAB43:GTP binds USP8NL IEA Sus scrofa A0A286ZPU3 R-SSC-6791227 https://reactome.org/PathwayBrowser/#/R-SSC-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Sus scrofa A0A286ZPV1 R-SSC-8940388 https://reactome.org/PathwayBrowser/#/R-SSC-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Sus scrofa A0A286ZPW1 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZPW1 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A286ZPW1 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZPW1 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A286ZPX1 R-SSC-5577237 https://reactome.org/PathwayBrowser/#/R-SSC-5577237 KCNH2:KCNE transport K+ from cytosol to extracellular region IEA Sus scrofa A0A286ZPX1 R-SSC-9613264 https://reactome.org/PathwayBrowser/#/R-SSC-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Sus scrofa A0A286ZPZ6 R-SSC-5687360 https://reactome.org/PathwayBrowser/#/R-SSC-5687360 POLL or POLM extends aligned DNA DSB ends to fill gaps IEA Sus scrofa A0A286ZQ02 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A286ZQ11 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A286ZQ11 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A286ZQ11 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A286ZQ11 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A286ZQ11 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A286ZQ11 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A286ZQ11 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A286ZQ11 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A286ZQ11 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A286ZQ11 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A286ZQ11 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A286ZQ11 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A286ZQ11 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A286ZQ11 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A286ZQ11 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A286ZQ11 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A286ZQ11 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A286ZQ11 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A286ZQ11 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A286ZQ11 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A286ZQ11 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A286ZQ27 R-SSC-70420 https://reactome.org/PathwayBrowser/#/R-SSC-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Sus scrofa A0A286ZQ31 R-SSC-6798335 https://reactome.org/PathwayBrowser/#/R-SSC-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Sus scrofa A0A286ZQ44 R-SSC-5661240 https://reactome.org/PathwayBrowser/#/R-SSC-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Sus scrofa A0A286ZQ50 R-SSC-111439 https://reactome.org/PathwayBrowser/#/R-SSC-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Sus scrofa A0A286ZQ50 R-SSC-158441 https://reactome.org/PathwayBrowser/#/R-SSC-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Sus scrofa A0A286ZQ50 R-SSC-158447 https://reactome.org/PathwayBrowser/#/R-SSC-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Sus scrofa A0A286ZQ50 R-SSC-158481 https://reactome.org/PathwayBrowser/#/R-SSC-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Sus scrofa A0A286ZQ50 R-SSC-158484 https://reactome.org/PathwayBrowser/#/R-SSC-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Sus scrofa A0A286ZQ50 R-SSC-159046 https://reactome.org/PathwayBrowser/#/R-SSC-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Sus scrofa A0A286ZQ50 R-SSC-159050 https://reactome.org/PathwayBrowser/#/R-SSC-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Sus scrofa A0A286ZQ50 R-SSC-191830 https://reactome.org/PathwayBrowser/#/R-SSC-191830 snRNP nuclear import and release IEA Sus scrofa A0A286ZQ50 R-SSC-2990880 https://reactome.org/PathwayBrowser/#/R-SSC-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Sus scrofa A0A286ZQ50 R-SSC-2990882 https://reactome.org/PathwayBrowser/#/R-SSC-2990882 CDK1 phosphorylates NUP98 IEA Sus scrofa A0A286ZQ50 R-SSC-3000348 https://reactome.org/PathwayBrowser/#/R-SSC-3000348 RANBP2 SUMOylates SP100 with SUMO2 IEA Sus scrofa A0A286ZQ50 R-SSC-3000399 https://reactome.org/PathwayBrowser/#/R-SSC-3000399 RANBP2 SUMOylates SP100 with SUMO1 IEA Sus scrofa A0A286ZQ50 R-SSC-3000411 https://reactome.org/PathwayBrowser/#/R-SSC-3000411 RANBP2 SUMOylates PML with SUMO2 IEA Sus scrofa A0A286ZQ50 R-SSC-4551649 https://reactome.org/PathwayBrowser/#/R-SSC-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Sus scrofa A0A286ZQ50 R-SSC-4551679 https://reactome.org/PathwayBrowser/#/R-SSC-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Sus scrofa A0A286ZQ50 R-SSC-4570493 https://reactome.org/PathwayBrowser/#/R-SSC-4570493 RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 IEA Sus scrofa A0A286ZQ50 R-SSC-4615872 https://reactome.org/PathwayBrowser/#/R-SSC-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Sus scrofa A0A286ZQ50 R-SSC-4615987 https://reactome.org/PathwayBrowser/#/R-SSC-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Sus scrofa A0A286ZQ50 R-SSC-4655355 https://reactome.org/PathwayBrowser/#/R-SSC-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Sus scrofa A0A286ZQ50 R-SSC-5228508 https://reactome.org/PathwayBrowser/#/R-SSC-5228508 RANBP2 SUMOylates PML with SUMO1 IEA Sus scrofa A0A286ZQ50 R-SSC-5228523 https://reactome.org/PathwayBrowser/#/R-SSC-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Sus scrofa A0A286ZQ50 R-SSC-5252041 https://reactome.org/PathwayBrowser/#/R-SSC-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Sus scrofa A0A286ZQ50 R-SSC-5578744 https://reactome.org/PathwayBrowser/#/R-SSC-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Sus scrofa A0A286ZQ50 R-SSC-75097 https://reactome.org/PathwayBrowser/#/R-SSC-75097 Transport of the export-competent mRNP complex through the NPC IEA Sus scrofa A0A286ZQ50 R-SSC-75098 https://reactome.org/PathwayBrowser/#/R-SSC-75098 mRNP complex dissociates from cytosolic face of NPC IEA Sus scrofa A0A286ZQ50 R-SSC-77587 https://reactome.org/PathwayBrowser/#/R-SSC-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Sus scrofa A0A286ZQ50 R-SSC-77594 https://reactome.org/PathwayBrowser/#/R-SSC-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Sus scrofa A0A286ZQ50 R-SSC-9634169 https://reactome.org/PathwayBrowser/#/R-SSC-9634169 POM121 and NDC1 bind the Nup93 complex IEA Sus scrofa A0A286ZQ85 R-SSC-1454757 https://reactome.org/PathwayBrowser/#/R-SSC-1454757 Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 IEA Sus scrofa A0A286ZQ85 R-SSC-1474210 https://reactome.org/PathwayBrowser/#/R-SSC-1474210 Collagen type III degradation by MMP14 IEA Sus scrofa A0A286ZQ85 R-SSC-1474213 https://reactome.org/PathwayBrowser/#/R-SSC-1474213 Collagen type III degradation by MMP1,8,9,13 IEA Sus scrofa A0A286ZQ85 R-SSC-1474266 https://reactome.org/PathwayBrowser/#/R-SSC-1474266 Formation of collagen fibrils IEA Sus scrofa A0A286ZQ85 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa A0A286ZQ85 R-SSC-1981104 https://reactome.org/PathwayBrowser/#/R-SSC-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Sus scrofa A0A286ZQ85 R-SSC-1981120 https://reactome.org/PathwayBrowser/#/R-SSC-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Sus scrofa A0A286ZQ85 R-SSC-1981128 https://reactome.org/PathwayBrowser/#/R-SSC-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Sus scrofa A0A286ZQ85 R-SSC-1981157 https://reactome.org/PathwayBrowser/#/R-SSC-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Sus scrofa A0A286ZQ85 R-SSC-2002428 https://reactome.org/PathwayBrowser/#/R-SSC-2002428 Removal of fibrillar collagen N-propeptides IEA Sus scrofa A0A286ZQ85 R-SSC-2002440 https://reactome.org/PathwayBrowser/#/R-SSC-2002440 Removal of fibrillar collagen C-propeptides IEA Sus scrofa A0A286ZQ85 R-SSC-2002460 https://reactome.org/PathwayBrowser/#/R-SSC-2002460 P4HB binds Collagen chains IEA Sus scrofa A0A286ZQ85 R-SSC-2089971 https://reactome.org/PathwayBrowser/#/R-SSC-2089971 Secretion of collagens IEA Sus scrofa A0A286ZQ85 R-SSC-2213201 https://reactome.org/PathwayBrowser/#/R-SSC-2213201 Formation of collagen fibres IEA Sus scrofa A0A286ZQ85 R-SSC-2327695 https://reactome.org/PathwayBrowser/#/R-SSC-2327695 Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 IEA Sus scrofa A0A286ZQ85 R-SSC-2327733 https://reactome.org/PathwayBrowser/#/R-SSC-2327733 FN1 binds Collagen types I-V, VII IEA Sus scrofa A0A286ZQ85 R-SSC-2327738 https://reactome.org/PathwayBrowser/#/R-SSC-2327738 DDR1 binds collagen type I, II, III, IV, V, XI fibrils IEA Sus scrofa A0A286ZQ85 R-SSC-2327909 https://reactome.org/PathwayBrowser/#/R-SSC-2327909 DCN binds collagen I, II, III, VI fibrils IEA Sus scrofa A0A286ZQ85 R-SSC-2396370 https://reactome.org/PathwayBrowser/#/R-SSC-2396370 VTN binds collagens II, III and V IEA Sus scrofa A0A286ZQ85 R-SSC-2465890 https://reactome.org/PathwayBrowser/#/R-SSC-2465890 DDR2 binds collagen type I, II, III, V, X fibrils IEA Sus scrofa A0A286ZQ85 R-SSC-2473584 https://reactome.org/PathwayBrowser/#/R-SSC-2473584 Collagen type III degradation by MMP15 IEA Sus scrofa A0A286ZQ85 R-SSC-382054 https://reactome.org/PathwayBrowser/#/R-SSC-382054 PDGF binds to extracellular matrix proteins IEA Sus scrofa A0A286ZQ85 R-SSC-5696356 https://reactome.org/PathwayBrowser/#/R-SSC-5696356 OSCAR binds collagen and SP-D IEA Sus scrofa A0A286ZQ85 R-SSC-5696357 https://reactome.org/PathwayBrowser/#/R-SSC-5696357 LAIR2 binds collagen IEA Sus scrofa A0A286ZQ85 R-SSC-8944240 https://reactome.org/PathwayBrowser/#/R-SSC-8944240 Association of procollagen type III IEA Sus scrofa A0A286ZQ85 R-SSC-8948219 https://reactome.org/PathwayBrowser/#/R-SSC-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A286ZQ85 R-SSC-8948222 https://reactome.org/PathwayBrowser/#/R-SSC-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A286ZQ85 R-SSC-8948224 https://reactome.org/PathwayBrowser/#/R-SSC-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A286ZQ85 R-SSC-8948228 https://reactome.org/PathwayBrowser/#/R-SSC-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A286ZQ85 R-SSC-8948231 https://reactome.org/PathwayBrowser/#/R-SSC-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A286ZQ85 R-SSC-8948232 https://reactome.org/PathwayBrowser/#/R-SSC-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Sus scrofa A0A286ZQ85 R-SSC-8948234 https://reactome.org/PathwayBrowser/#/R-SSC-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Sus scrofa A0A286ZQA0 R-SSC-450387 https://reactome.org/PathwayBrowser/#/R-SSC-450387 HuR binds the CRM1 nuclear export machinery IEA Sus scrofa A0A286ZQA0 R-SSC-450595 https://reactome.org/PathwayBrowser/#/R-SSC-450595 HuR:mRNA complex translocates from the nucleus to the cytosol IEA Sus scrofa A0A286ZQA0 R-SSC-5676607 https://reactome.org/PathwayBrowser/#/R-SSC-5676607 sBAFF,sAPRIL binds TACI,BCMA IEA Sus scrofa A0A286ZQA3 R-SSC-3299569 https://reactome.org/PathwayBrowser/#/R-SSC-3299569 Beta-catenin displaces TLE:HDAC1 from TCF/LEF IEA Sus scrofa A0A286ZQA3 R-SSC-3322429 https://reactome.org/PathwayBrowser/#/R-SSC-3322429 XIAP monoubiquinates TLE IEA Sus scrofa A0A286ZQA3 R-SSC-3322431 https://reactome.org/PathwayBrowser/#/R-SSC-3322431 XIAP binds TLE IEA Sus scrofa A0A286ZQA3 R-SSC-3322434 https://reactome.org/PathwayBrowser/#/R-SSC-3322434 XIAP dissociates from ub-TLE IEA Sus scrofa A0A286ZQA3 R-SSC-3361751 https://reactome.org/PathwayBrowser/#/R-SSC-3361751 beta-catenin is replaced by repression complexes at the promoter IEA Sus scrofa A0A286ZQA3 R-SSC-4641229 https://reactome.org/PathwayBrowser/#/R-SSC-4641229 TLE oligomerizes IEA Sus scrofa A0A286ZQA3 R-SSC-8944349 https://reactome.org/PathwayBrowser/#/R-SSC-8944349 TLE tetramers bind TCF/LEF at WNT promoters IEA Sus scrofa A0A286ZQA8 R-SSC-622326 https://reactome.org/PathwayBrowser/#/R-SSC-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Sus scrofa A0A286ZQA8 R-SSC-629595 https://reactome.org/PathwayBrowser/#/R-SSC-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Sus scrofa A0A286ZQA8 R-SSC-629596 https://reactome.org/PathwayBrowser/#/R-SSC-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Sus scrofa A0A286ZQA8 R-SSC-629599 https://reactome.org/PathwayBrowser/#/R-SSC-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Sus scrofa A0A286ZQB5 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa A0A286ZQB5 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa A0A286ZQB5 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa A0A286ZQB6 R-SSC-112379 https://reactome.org/PathwayBrowser/#/R-SSC-112379 Recruitment of elongation factors to form elongation complex IEA Sus scrofa A0A286ZQB6 R-SSC-112381 https://reactome.org/PathwayBrowser/#/R-SSC-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Sus scrofa A0A286ZQB6 R-SSC-112385 https://reactome.org/PathwayBrowser/#/R-SSC-112385 Addition of nucleotides leads to transcript elongation IEA Sus scrofa A0A286ZQB6 R-SSC-112392 https://reactome.org/PathwayBrowser/#/R-SSC-112392 Resumption of elongation after recovery from pausing IEA Sus scrofa A0A286ZQB6 R-SSC-112395 https://reactome.org/PathwayBrowser/#/R-SSC-112395 Abortive termination of elongation after arrest IEA Sus scrofa A0A286ZQB6 R-SSC-112396 https://reactome.org/PathwayBrowser/#/R-SSC-112396 Separation of elongating transcript from template IEA Sus scrofa A0A286ZQB6 R-SSC-112430 https://reactome.org/PathwayBrowser/#/R-SSC-112430 Formation of P-TEFb complex IEA Sus scrofa A0A286ZQB6 R-SSC-113411 https://reactome.org/PathwayBrowser/#/R-SSC-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Sus scrofa A0A286ZQB6 R-SSC-113412 https://reactome.org/PathwayBrowser/#/R-SSC-113412 Pol II elongation complex moves on the template as transcript elongates IEA Sus scrofa A0A286ZQB6 R-SSC-113413 https://reactome.org/PathwayBrowser/#/R-SSC-113413 TFIIS-mediated recovery of elongation from arrest IEA Sus scrofa A0A286ZQB6 R-SSC-113414 https://reactome.org/PathwayBrowser/#/R-SSC-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Sus scrofa A0A286ZQB6 R-SSC-113429 https://reactome.org/PathwayBrowser/#/R-SSC-113429 Elongating transcript encounters a lesion in the template IEA Sus scrofa A0A286ZQB6 R-SSC-2176475 https://reactome.org/PathwayBrowser/#/R-SSC-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Sus scrofa A0A286ZQB6 R-SSC-6797606 https://reactome.org/PathwayBrowser/#/R-SSC-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Sus scrofa A0A286ZQB6 R-SSC-6797616 https://reactome.org/PathwayBrowser/#/R-SSC-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Sus scrofa A0A286ZQB6 R-SSC-6810233 https://reactome.org/PathwayBrowser/#/R-SSC-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Sus scrofa A0A286ZQB6 R-SSC-6810235 https://reactome.org/PathwayBrowser/#/R-SSC-6810235 RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain IEA Sus scrofa A0A286ZQB6 R-SSC-6810238 https://reactome.org/PathwayBrowser/#/R-SSC-6810238 RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) IEA Sus scrofa A0A286ZQB6 R-SSC-6814549 https://reactome.org/PathwayBrowser/#/R-SSC-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Sus scrofa A0A286ZQB6 R-SSC-6814555 https://reactome.org/PathwayBrowser/#/R-SSC-6814555 Integrator complex processes the 3' end of snRNA IEA Sus scrofa A0A286ZQB6 R-SSC-6814559 https://reactome.org/PathwayBrowser/#/R-SSC-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Sus scrofa A0A286ZQB6 R-SSC-6814885 https://reactome.org/PathwayBrowser/#/R-SSC-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Sus scrofa A0A286ZQB6 R-SSC-9012315 https://reactome.org/PathwayBrowser/#/R-SSC-9012315 ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene IEA Sus scrofa A0A286ZQB6 R-SSC-9012319 https://reactome.org/PathwayBrowser/#/R-SSC-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Sus scrofa A0A286ZQC1 R-SSC-1306876 https://reactome.org/PathwayBrowser/#/R-SSC-1306876 NLRP3 activation by small molecules IEA Sus scrofa A0A286ZQC1 R-SSC-873951 https://reactome.org/PathwayBrowser/#/R-SSC-873951 SGT1:HSP90 binds inactive NLRP3 IEA Sus scrofa A0A286ZQC1 R-SSC-874087 https://reactome.org/PathwayBrowser/#/R-SSC-874087 SGT1 binds HSP90 IEA Sus scrofa A0A286ZQC3 R-SSC-4420140 https://reactome.org/PathwayBrowser/#/R-SSC-4420140 SRC1-1 binds SH2D2A and is recruited to VEGFR2 IEA Sus scrofa A0A286ZQC3 R-SSC-4420143 https://reactome.org/PathwayBrowser/#/R-SSC-4420143 p-6Y-VEGFR2 binds SH2D2A IEA Sus scrofa A0A286ZQC3 R-SSC-4420206 https://reactome.org/PathwayBrowser/#/R-SSC-4420206 Phosphorylation of SRC-1 IEA Sus scrofa A0A286ZQC3 R-SSC-5218819 https://reactome.org/PathwayBrowser/#/R-SSC-5218819 VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZQC3 R-SSC-5357429 https://reactome.org/PathwayBrowser/#/R-SSC-5357429 AXL autophosphorylates on Y779 and Y821 IEA Sus scrofa A0A286ZQC3 R-SSC-5357432 https://reactome.org/PathwayBrowser/#/R-SSC-5357432 AXL binds SRC-1 IEA Sus scrofa A0A286ZQC3 R-SSC-5357479 https://reactome.org/PathwayBrowser/#/R-SSC-5357479 p-AXL binds PI3K IEA Sus scrofa A0A286ZQC7 R-SSC-174587 https://reactome.org/PathwayBrowser/#/R-SSC-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Sus scrofa A0A286ZQC7 R-SSC-174660 https://reactome.org/PathwayBrowser/#/R-SSC-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Sus scrofa A0A286ZQC7 R-SSC-174690 https://reactome.org/PathwayBrowser/#/R-SSC-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Sus scrofa A0A286ZQC7 R-SSC-174741 https://reactome.org/PathwayBrowser/#/R-SSC-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Sus scrofa A0A286ZQC7 R-SSC-174757 https://reactome.org/PathwayBrowser/#/R-SSC-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Sus scrofa A0A286ZQC7 R-SSC-216723 https://reactome.org/PathwayBrowser/#/R-SSC-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Sus scrofa A0A286ZQC7 R-SSC-216727 https://reactome.org/PathwayBrowser/#/R-SSC-216727 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 IEA Sus scrofa A0A286ZQC7 R-SSC-216756 https://reactome.org/PathwayBrowser/#/R-SSC-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Sus scrofa A0A286ZQC7 R-SSC-216757 https://reactome.org/PathwayBrowser/#/R-SSC-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Sus scrofa A0A286ZQC7 R-SSC-2168889 https://reactome.org/PathwayBrowser/#/R-SSC-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Sus scrofa A0A286ZQC7 R-SSC-2187332 https://reactome.org/PathwayBrowser/#/R-SSC-2187332 Cytosolic CMs translocate to extracellular region IEA Sus scrofa A0A286ZQC7 R-SSC-2197646 https://reactome.org/PathwayBrowser/#/R-SSC-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Sus scrofa A0A286ZQC7 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa A0A286ZQC7 R-SSC-2395764 https://reactome.org/PathwayBrowser/#/R-SSC-2395764 atREs binds to nascent CM IEA Sus scrofa A0A286ZQC7 R-SSC-2395768 https://reactome.org/PathwayBrowser/#/R-SSC-2395768 LPL hydrolyses TGs from mature CMs IEA Sus scrofa A0A286ZQC7 R-SSC-2395784 https://reactome.org/PathwayBrowser/#/R-SSC-2395784 Nascent CMs transform into mature CMs IEA Sus scrofa A0A286ZQC7 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa A0A286ZQC7 R-SSC-2423785 https://reactome.org/PathwayBrowser/#/R-SSC-2423785 CR:atREs binds apoE and HSPG IEA Sus scrofa A0A286ZQC7 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa A0A286ZQC7 R-SSC-264678 https://reactome.org/PathwayBrowser/#/R-SSC-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex IEA Sus scrofa A0A286ZQC7 R-SSC-264689 https://reactome.org/PathwayBrowser/#/R-SSC-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL IEA Sus scrofa A0A286ZQC7 R-SSC-264695 https://reactome.org/PathwayBrowser/#/R-SSC-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Sus scrofa A0A286ZQC7 R-SSC-264758 https://reactome.org/PathwayBrowser/#/R-SSC-264758 BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 IEA Sus scrofa A0A286ZQC7 R-SSC-266089 https://reactome.org/PathwayBrowser/#/R-SSC-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Sus scrofa A0A286ZQC7 R-SSC-266299 https://reactome.org/PathwayBrowser/#/R-SSC-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Sus scrofa A0A286ZQC7 R-SSC-266303 https://reactome.org/PathwayBrowser/#/R-SSC-266303 Spherical HDL binds C and E apolipoproteins IEA Sus scrofa A0A286ZQC7 R-SSC-266310 https://reactome.org/PathwayBrowser/#/R-SSC-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Sus scrofa A0A286ZQC7 R-SSC-266315 https://reactome.org/PathwayBrowser/#/R-SSC-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Sus scrofa A0A286ZQC7 R-SSC-349637 https://reactome.org/PathwayBrowser/#/R-SSC-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Sus scrofa A0A286ZQC7 R-SSC-349638 https://reactome.org/PathwayBrowser/#/R-SSC-349638 Disassembly of SR-BI-bound spherical HDL IEA Sus scrofa A0A286ZQC7 R-SSC-349657 https://reactome.org/PathwayBrowser/#/R-SSC-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Sus scrofa A0A286ZQC7 R-SSC-382553 https://reactome.org/PathwayBrowser/#/R-SSC-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Sus scrofa A0A286ZQC7 R-SSC-482770 https://reactome.org/PathwayBrowser/#/R-SSC-482770 Release of platelet secretory granule components IEA Sus scrofa A0A286ZQC7 R-SSC-8858252 https://reactome.org/PathwayBrowser/#/R-SSC-8858252 HDLBP binds HDL IEA Sus scrofa A0A286ZQC7 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A286ZQC7 R-SSC-9707586 https://reactome.org/PathwayBrowser/#/R-SSC-9707586 FeHM oxidises LDL,HDL IEA Sus scrofa A0A286ZQD2 R-SSC-6794347 https://reactome.org/PathwayBrowser/#/R-SSC-6794347 Homer1,2,3 dimerizes IEA Sus scrofa A0A286ZQD2 R-SSC-6794355 https://reactome.org/PathwayBrowser/#/R-SSC-6794355 Homer1,2,3 binds mGluR1a,5 IEA Sus scrofa A0A286ZQE1 R-SSC-1112690 https://reactome.org/PathwayBrowser/#/R-SSC-1112690 PTPN11 binds CBL IEA Sus scrofa A0A286ZQE1 R-SSC-1295621 https://reactome.org/PathwayBrowser/#/R-SSC-1295621 CBL dissociates from ubiquitinated p-SPRY2 IEA Sus scrofa A0A286ZQE1 R-SSC-1295622 https://reactome.org/PathwayBrowser/#/R-SSC-1295622 SPRY2 binds CBL IEA Sus scrofa A0A286ZQE1 R-SSC-182969 https://reactome.org/PathwayBrowser/#/R-SSC-182969 Phosphorylation of CBL (EGFR:CBL) IEA Sus scrofa A0A286ZQE1 R-SSC-182986 https://reactome.org/PathwayBrowser/#/R-SSC-182986 CBL-mediated ubiquitination of CIN85 IEA Sus scrofa A0A286ZQE1 R-SSC-182988 https://reactome.org/PathwayBrowser/#/R-SSC-182988 Sprouty lures CBL away from EGFR IEA Sus scrofa A0A286ZQE1 R-SSC-182990 https://reactome.org/PathwayBrowser/#/R-SSC-182990 Sprouty sequesters CBL away from active EGFR IEA Sus scrofa A0A286ZQE1 R-SSC-182993 https://reactome.org/PathwayBrowser/#/R-SSC-182993 Ubiquitination of stimulated EGFR (CBL) IEA Sus scrofa A0A286ZQE1 R-SSC-182994 https://reactome.org/PathwayBrowser/#/R-SSC-182994 Assembly of EGFR complex in clathrin-coated vesicles IEA Sus scrofa A0A286ZQE1 R-SSC-183002 https://reactome.org/PathwayBrowser/#/R-SSC-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Sus scrofa A0A286ZQE1 R-SSC-183036 https://reactome.org/PathwayBrowser/#/R-SSC-183036 Ubiquitination of stimulated EGFR (CBL:GRB2) IEA Sus scrofa A0A286ZQE1 R-SSC-183051 https://reactome.org/PathwayBrowser/#/R-SSC-183051 CBL ubiquitinates Sprouty IEA Sus scrofa A0A286ZQE1 R-SSC-183052 https://reactome.org/PathwayBrowser/#/R-SSC-183052 CBL binds to GRB2 IEA Sus scrofa A0A286ZQE1 R-SSC-183055 https://reactome.org/PathwayBrowser/#/R-SSC-183055 Binding of CBL to EGFR IEA Sus scrofa A0A286ZQE1 R-SSC-183058 https://reactome.org/PathwayBrowser/#/R-SSC-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Sus scrofa A0A286ZQE1 R-SSC-183067 https://reactome.org/PathwayBrowser/#/R-SSC-183067 Localization of CBL:GRB2 to the membrane IEA Sus scrofa A0A286ZQE1 R-SSC-183072 https://reactome.org/PathwayBrowser/#/R-SSC-183072 EGFR non-clathrin mediated endocytosis IEA Sus scrofa A0A286ZQE1 R-SSC-183084 https://reactome.org/PathwayBrowser/#/R-SSC-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Sus scrofa A0A286ZQE1 R-SSC-183089 https://reactome.org/PathwayBrowser/#/R-SSC-183089 CBL binds and ubiquitinates phosphorylated Sprouty IEA Sus scrofa A0A286ZQE1 R-SSC-183094 https://reactome.org/PathwayBrowser/#/R-SSC-183094 CDC42:GTP binds CBL:Beta-Pix IEA Sus scrofa A0A286ZQE1 R-SSC-205244 https://reactome.org/PathwayBrowser/#/R-SSC-205244 Recruitment of CBL to KIT IEA Sus scrofa A0A286ZQE1 R-SSC-4332235 https://reactome.org/PathwayBrowser/#/R-SSC-4332235 CBL binds TGFBR2 IEA Sus scrofa A0A286ZQE1 R-SSC-4332236 https://reactome.org/PathwayBrowser/#/R-SSC-4332236 CBL neddylates TGFBR2 IEA Sus scrofa A0A286ZQE1 R-SSC-5654672 https://reactome.org/PathwayBrowser/#/R-SSC-5654672 CBL ubiquitinates FRS2 and FGFR1 IEA Sus scrofa A0A286ZQE1 R-SSC-5654673 https://reactome.org/PathwayBrowser/#/R-SSC-5654673 p-CBL:GRB2 binds p-FRS2:activated FGFR1 IEA Sus scrofa A0A286ZQE1 R-SSC-5654677 https://reactome.org/PathwayBrowser/#/R-SSC-5654677 CBL ubiquitinates FRS2 and FGFR2 IEA Sus scrofa A0A286ZQE1 R-SSC-5654679 https://reactome.org/PathwayBrowser/#/R-SSC-5654679 CBL ubiquitinates FRS2 and FGFR3 IEA Sus scrofa A0A286ZQE1 R-SSC-5654684 https://reactome.org/PathwayBrowser/#/R-SSC-5654684 CBL ubiquitinates FRS2 and FGFR4 IEA Sus scrofa A0A286ZQE1 R-SSC-5654729 https://reactome.org/PathwayBrowser/#/R-SSC-5654729 p-CBL:GRB2 binds p-FRS2:activated FGFR2 IEA Sus scrofa A0A286ZQE1 R-SSC-5654730 https://reactome.org/PathwayBrowser/#/R-SSC-5654730 p-CBL:GRB2 binds p-FRS2:activated FGFR3 IEA Sus scrofa A0A286ZQE1 R-SSC-5654734 https://reactome.org/PathwayBrowser/#/R-SSC-5654734 p-CBL:GRB2 binds p-FRS2:activated FGFR4 IEA Sus scrofa A0A286ZQE1 R-SSC-879917 https://reactome.org/PathwayBrowser/#/R-SSC-879917 CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated IEA Sus scrofa A0A286ZQE1 R-SSC-8848818 https://reactome.org/PathwayBrowser/#/R-SSC-8848818 PTK6 phosphorylates CBL IEA Sus scrofa A0A286ZQE1 R-SSC-8848829 https://reactome.org/PathwayBrowser/#/R-SSC-8848829 CBL autoubiquitinates IEA Sus scrofa A0A286ZQE1 R-SSC-8866279 https://reactome.org/PathwayBrowser/#/R-SSC-8866279 Epsin family proteins bind ubiquitinated cargo IEA Sus scrofa A0A286ZQE1 R-SSC-8867041 https://reactome.org/PathwayBrowser/#/R-SSC-8867041 EGFR phosphorylates EPS15 IEA Sus scrofa A0A286ZQE1 R-SSC-8867044 https://reactome.org/PathwayBrowser/#/R-SSC-8867044 EGFR binds EPS15, EPN1, EPS15L1 IEA Sus scrofa A0A286ZQE1 R-SSC-8867047 https://reactome.org/PathwayBrowser/#/R-SSC-8867047 PTPN3 dephosphorylates EPS15 IEA Sus scrofa A0A286ZQE1 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A286ZQE1 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A286ZQE1 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A286ZQE1 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A286ZQE1 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A286ZQE1 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A286ZQE1 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A286ZQE1 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A286ZQE1 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A286ZQE1 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A286ZQE1 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A286ZQE1 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A286ZQE1 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A286ZQE1 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A286ZQE1 R-SSC-8874685 https://reactome.org/PathwayBrowser/#/R-SSC-8874685 CBL binds MET IEA Sus scrofa A0A286ZQE1 R-SSC-8875183 https://reactome.org/PathwayBrowser/#/R-SSC-8875183 CBL monoubiquitinates activated MET IEA Sus scrofa A0A286ZQE1 R-SSC-8875451 https://reactome.org/PathwayBrowser/#/R-SSC-8875451 MET phosphorylates CBL IEA Sus scrofa A0A286ZQE1 R-SSC-8875482 https://reactome.org/PathwayBrowser/#/R-SSC-8875482 CBL recruits CIN85:endophilin to ubiquitinated MET IEA Sus scrofa A0A286ZQE1 R-SSC-8875490 https://reactome.org/PathwayBrowser/#/R-SSC-8875490 EPS15 and HGS bind ubiquitinated MET IEA Sus scrofa A0A286ZQE1 R-SSC-8951490 https://reactome.org/PathwayBrowser/#/R-SSC-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Sus scrofa A0A286ZQE1 R-SSC-912627 https://reactome.org/PathwayBrowser/#/R-SSC-912627 CBL ubiquitinates PI3K IEA Sus scrofa A0A286ZQE1 R-SSC-912727 https://reactome.org/PathwayBrowser/#/R-SSC-912727 CBL binds VAV IEA Sus scrofa A0A286ZQE1 R-SSC-912734 https://reactome.org/PathwayBrowser/#/R-SSC-912734 CBL:CRKL binds RAPGEF1 IEA Sus scrofa A0A286ZQE1 R-SSC-912790 https://reactome.org/PathwayBrowser/#/R-SSC-912790 CBL binds CRK IEA Sus scrofa A0A286ZQE1 R-SSC-934604 https://reactome.org/PathwayBrowser/#/R-SSC-934604 Phosphorylated SPRY2 is ubiquitinated by CBL IEA Sus scrofa A0A286ZQE1 R-SSC-9706293 https://reactome.org/PathwayBrowser/#/R-SSC-9706293 Active FLT3 binds to CBL IEA Sus scrofa A0A286ZQE1 R-SSC-9706350 https://reactome.org/PathwayBrowser/#/R-SSC-9706350 FLT3 phosphorylates CBL IEA Sus scrofa A0A286ZQE1 R-SSC-9706354 https://reactome.org/PathwayBrowser/#/R-SSC-9706354 Ubiquitination of FLT3 IEA Sus scrofa A0A286ZQF1 R-SSC-5218952 https://reactome.org/PathwayBrowser/#/R-SSC-5218952 PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) IEA Sus scrofa A0A286ZQG3 R-SSC-141156 https://reactome.org/PathwayBrowser/#/R-SSC-141156 TRAIL-mediated dimerization of procaspase-8 IEA Sus scrofa A0A286ZQG3 R-SSC-3371359 https://reactome.org/PathwayBrowser/#/R-SSC-3371359 FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling IEA Sus scrofa A0A286ZQG3 R-SSC-5635741 https://reactome.org/PathwayBrowser/#/R-SSC-5635741 TRAIL receptor-4 binds TRAIL receptor-1 or TRAIL receptor-2 IEA Sus scrofa A0A286ZQH2 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A286ZQH2 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A286ZQH2 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A286ZQH2 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A286ZQH2 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A286ZQH2 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A286ZQH2 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A286ZQH2 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A286ZQH2 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A286ZQH2 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZQH2 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A286ZQH2 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A286ZQH2 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A286ZQH2 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A286ZQH2 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A286ZQH2 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A286ZQH2 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A286ZQH2 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A286ZQH2 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A286ZQH2 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A286ZQH2 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A286ZQH2 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A286ZQH2 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A286ZQH2 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A286ZQH2 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A286ZQH2 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A286ZQH2 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A286ZQH2 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A286ZQH2 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A286ZQH2 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A286ZQH2 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A286ZQH2 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A286ZQH2 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A286ZQH2 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A286ZQH2 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A286ZQH2 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A286ZQH2 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A286ZQH2 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A286ZQH2 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A286ZQH2 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A286ZQH2 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A286ZQH2 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A286ZQH2 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A286ZQH2 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A286ZQH2 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A286ZQH2 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A286ZQH2 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A286ZQH3 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A286ZQH4 R-SSC-204465 https://reactome.org/PathwayBrowser/#/R-SSC-204465 Basigin interacts with CD43 IEA Sus scrofa A0A286ZQH4 R-SSC-2870221 https://reactome.org/PathwayBrowser/#/R-SSC-2870221 E-selectin binds E-selectin ligand IEA Sus scrofa A0A286ZQI3 R-SSC-200326 https://reactome.org/PathwayBrowser/#/R-SSC-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] IEA Sus scrofa A0A286ZQJ2 R-SSC-114252 https://reactome.org/PathwayBrowser/#/R-SSC-114252 Cleavage of Procaspase-3 by the apoptosome IEA Sus scrofa A0A286ZQJ2 R-SSC-114254 https://reactome.org/PathwayBrowser/#/R-SSC-114254 CYCS binds to APAF1 IEA Sus scrofa A0A286ZQJ2 R-SSC-114256 https://reactome.org/PathwayBrowser/#/R-SSC-114256 CYCS:APAF1 binds procaspase-9 IEA Sus scrofa A0A286ZQJ2 R-SSC-114259 https://reactome.org/PathwayBrowser/#/R-SSC-114259 Cleavage of Procaspase‑9 to caspase‑9 IEA Sus scrofa A0A286ZQJ2 R-SSC-114261 https://reactome.org/PathwayBrowser/#/R-SSC-114261 Cleavage of Procaspase-7 by the apoptosome IEA Sus scrofa A0A286ZQJ2 R-SSC-114284 https://reactome.org/PathwayBrowser/#/R-SSC-114284 Release of Cytochrome c from mitochondria IEA Sus scrofa A0A286ZQJ2 R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa A0A286ZQJ2 R-SSC-164651 https://reactome.org/PathwayBrowser/#/R-SSC-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Sus scrofa A0A286ZQJ2 R-SSC-3341294 https://reactome.org/PathwayBrowser/#/R-SSC-3341294 Superoxide reduces cytochrome c IEA Sus scrofa A0A286ZQJ2 R-SSC-5688294 https://reactome.org/PathwayBrowser/#/R-SSC-5688294 SIRT5 deacetylates Cytochrome C IEA Sus scrofa A0A286ZQJ2 R-SSC-6804596 https://reactome.org/PathwayBrowser/#/R-SSC-6804596 APAF1:CYCS binds APIP IEA Sus scrofa A0A286ZQJ2 R-SSC-9627056 https://reactome.org/PathwayBrowser/#/R-SSC-9627056 Procaspase 9 forms dimer IEA Sus scrofa A0A286ZQJ2 R-SSC-9627078 https://reactome.org/PathwayBrowser/#/R-SSC-9627078 XIAP binds CASP9 IEA Sus scrofa A0A286ZQJ2 R-SSC-9627089 https://reactome.org/PathwayBrowser/#/R-SSC-9627089 CASP9 is phosphorylated at T412 IEA Sus scrofa A0A286ZQJ2 R-SSC-9866217 https://reactome.org/PathwayBrowser/#/R-SSC-9866217 HCCS inserts heme into cytochrome c IEA Sus scrofa A0A286ZQJ8 R-SSC-5624949 https://reactome.org/PathwayBrowser/#/R-SSC-5624949 Assembly of the anterograde IFT train IEA Sus scrofa A0A286ZQJ8 R-SSC-5624952 https://reactome.org/PathwayBrowser/#/R-SSC-5624952 Assembly of the retrograde IFT train IEA Sus scrofa A0A286ZQJ8 R-SSC-5625416 https://reactome.org/PathwayBrowser/#/R-SSC-5625416 Anterograde IFT IEA Sus scrofa A0A286ZQJ8 R-SSC-5625421 https://reactome.org/PathwayBrowser/#/R-SSC-5625421 The anterograde IFT train dissociates IEA Sus scrofa A0A286ZQJ8 R-SSC-5625424 https://reactome.org/PathwayBrowser/#/R-SSC-5625424 The retrograde IFT train dissociates IEA Sus scrofa A0A286ZQJ8 R-SSC-5625426 https://reactome.org/PathwayBrowser/#/R-SSC-5625426 Retrograde IFT IEA Sus scrofa A0A286ZQM3 R-SSC-420582 https://reactome.org/PathwayBrowser/#/R-SSC-420582 Necl-1:Nectin-1 trans heterodimer interaction IEA Sus scrofa A0A286ZQM3 R-SSC-420584 https://reactome.org/PathwayBrowser/#/R-SSC-420584 Necl-1:Nectin 3 trans heterodimer interaction IEA Sus scrofa A0A286ZQM3 R-SSC-420586 https://reactome.org/PathwayBrowser/#/R-SSC-420586 Necl-1:Necl-2 trans heterodimer interaction IEA Sus scrofa A0A286ZQM3 R-SSC-420592 https://reactome.org/PathwayBrowser/#/R-SSC-420592 Transhomodimerization of Nectin-like (Necl) proteins IEA Sus scrofa A0A286ZQN3 R-SSC-9018017 https://reactome.org/PathwayBrowser/#/R-SSC-9018017 RB1 binds and inhibits E2F1/2/3:DP1/2 complexes IEA Sus scrofa A0A286ZQN7 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A286ZQN7 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A286ZQN7 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A286ZQN7 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A286ZQN7 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A286ZQT4 R-SSC-5173005 https://reactome.org/PathwayBrowser/#/R-SSC-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Sus scrofa A0A286ZQT4 R-SSC-5173192 https://reactome.org/PathwayBrowser/#/R-SSC-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Sus scrofa A0A286ZQU5 R-SSC-448661 https://reactome.org/PathwayBrowser/#/R-SSC-448661 IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 IEA Sus scrofa A0A286ZQU5 R-SSC-449811 https://reactome.org/PathwayBrowser/#/R-SSC-449811 IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 IEA Sus scrofa A0A286ZQU5 R-SSC-6784006 https://reactome.org/PathwayBrowser/#/R-SSC-6784006 STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 IEA Sus scrofa A0A286ZQU5 R-SSC-6784319 https://reactome.org/PathwayBrowser/#/R-SSC-6784319 JAK1,TYK2 phosphorylate JAK1,TYK2 IEA Sus scrofa A0A286ZQU5 R-SSC-6784323 https://reactome.org/PathwayBrowser/#/R-SSC-6784323 IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 IEA Sus scrofa A0A286ZQU5 R-SSC-6784324 https://reactome.org/PathwayBrowser/#/R-SSC-6784324 p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA IEA Sus scrofa A0A286ZQU5 R-SSC-6784791 https://reactome.org/PathwayBrowser/#/R-SSC-6784791 p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 IEA Sus scrofa A0A286ZQU5 R-SSC-8854645 https://reactome.org/PathwayBrowser/#/R-SSC-8854645 IL22:IL22RA1:JAK1 binds IL10RB:TYK2 IEA Sus scrofa A0A286ZQU5 R-SSC-8986480 https://reactome.org/PathwayBrowser/#/R-SSC-8986480 IL26:IL20RA:JAK1 binds IL10RB:TYK2 IEA Sus scrofa A0A286ZQU5 R-SSC-8986985 https://reactome.org/PathwayBrowser/#/R-SSC-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Sus scrofa A0A286ZQU5 R-SSC-8986994 https://reactome.org/PathwayBrowser/#/R-SSC-8986994 IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 IEA Sus scrofa A0A286ZQU5 R-SSC-8986995 https://reactome.org/PathwayBrowser/#/R-SSC-8986995 IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA IEA Sus scrofa A0A286ZQU5 R-SSC-8987014 https://reactome.org/PathwayBrowser/#/R-SSC-8987014 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 IEA Sus scrofa A0A286ZQU5 R-SSC-8987033 https://reactome.org/PathwayBrowser/#/R-SSC-8987033 p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 IEA Sus scrofa A0A286ZQU5 R-SSC-8987040 https://reactome.org/PathwayBrowser/#/R-SSC-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Sus scrofa A0A286ZQU5 R-SSC-8987042 https://reactome.org/PathwayBrowser/#/R-SSC-8987042 IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Sus scrofa A0A286ZQU5 R-SSC-8987070 https://reactome.org/PathwayBrowser/#/R-SSC-8987070 IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 IEA Sus scrofa A0A286ZQU5 R-SSC-8987080 https://reactome.org/PathwayBrowser/#/R-SSC-8987080 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 IEA Sus scrofa A0A286ZQU5 R-SSC-8987105 https://reactome.org/PathwayBrowser/#/R-SSC-8987105 IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 IEA Sus scrofa A0A286ZQU5 R-SSC-8987132 https://reactome.org/PathwayBrowser/#/R-SSC-8987132 IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11 IEA Sus scrofa A0A286ZQU5 R-SSC-8987202 https://reactome.org/PathwayBrowser/#/R-SSC-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Sus scrofa A0A286ZQU5 R-SSC-8987223 https://reactome.org/PathwayBrowser/#/R-SSC-8987223 IL10RB binds TYK2 IEA Sus scrofa A0A286ZQU5 R-SSC-8987230 https://reactome.org/PathwayBrowser/#/R-SSC-8987230 p-STAT1 and p-STAT3 dissociates from IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 IEA Sus scrofa A0A286ZQU5 R-SSC-8987236 https://reactome.org/PathwayBrowser/#/R-SSC-8987236 p-Y705-STAT3 dissociates from IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 IEA Sus scrofa A0A286ZQU5 R-SSC-8987255 https://reactome.org/PathwayBrowser/#/R-SSC-8987255 IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 IEA Sus scrofa A0A286ZQU5 R-SSC-8987266 https://reactome.org/PathwayBrowser/#/R-SSC-8987266 IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 IEA Sus scrofa A0A286ZQV1 R-SSC-8940388 https://reactome.org/PathwayBrowser/#/R-SSC-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Sus scrofa A0A286ZQV4 R-SSC-198870 https://reactome.org/PathwayBrowser/#/R-SSC-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol IEA Sus scrofa A0A286ZQV5 R-SSC-6798739 https://reactome.org/PathwayBrowser/#/R-SSC-6798739 Exocytosis of azurophil granule membrane proteins IEA Sus scrofa A0A286ZQV5 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A286ZQV9 R-SSC-5683385 https://reactome.org/PathwayBrowser/#/R-SSC-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Sus scrofa A0A286ZQV9 R-SSC-5683735 https://reactome.org/PathwayBrowser/#/R-SSC-5683735 CHEK2 is recruited to DNA DSBs IEA Sus scrofa A0A286ZQV9 R-SSC-5683801 https://reactome.org/PathwayBrowser/#/R-SSC-5683801 CHEK2 phosphorylates BRCA1 IEA Sus scrofa A0A286ZQV9 R-SSC-5684052 https://reactome.org/PathwayBrowser/#/R-SSC-5684052 PIAS4 SUMOylates MDC1 IEA Sus scrofa A0A286ZQV9 R-SSC-5686685 https://reactome.org/PathwayBrowser/#/R-SSC-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Sus scrofa A0A286ZQV9 R-SSC-5691411 https://reactome.org/PathwayBrowser/#/R-SSC-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Sus scrofa A0A286ZQV9 R-SSC-5691439 https://reactome.org/PathwayBrowser/#/R-SSC-5691439 BRISC complex deubiquitinates NLRP3 IEA Sus scrofa A0A286ZQV9 R-SSC-5693551 https://reactome.org/PathwayBrowser/#/R-SSC-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Sus scrofa A0A286ZQV9 R-SSC-69891 https://reactome.org/PathwayBrowser/#/R-SSC-69891 Phosphorylation and activation of CHEK2 by ATM IEA Sus scrofa A0A286ZQW0 R-SSC-9825759 https://reactome.org/PathwayBrowser/#/R-SSC-9825759 MAPK-dependent phosphorylation of KARS IEA Sus scrofa A0A286ZQW7 R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa A0A286ZQW7 R-SSC-9679787 https://reactome.org/PathwayBrowser/#/R-SSC-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Sus scrofa A0A286ZQW7 R-SSC-996727 https://reactome.org/PathwayBrowser/#/R-SSC-996727 REST recruits the BHC complex IEA Sus scrofa A0A286ZQX2 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A286ZQX2 R-SSC-1433415 https://reactome.org/PathwayBrowser/#/R-SSC-1433415 Activation of RAC1 IEA Sus scrofa A0A286ZQX2 R-SSC-1433542 https://reactome.org/PathwayBrowser/#/R-SSC-1433542 Phosphorylation and activation of VAV1 IEA Sus scrofa A0A286ZQX2 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A286ZQX2 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A286ZQX2 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A286ZQX2 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa A0A286ZQX2 R-SSC-2076220 https://reactome.org/PathwayBrowser/#/R-SSC-2076220 CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Sus scrofa A0A286ZQX2 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZQX2 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A286ZQX2 R-SSC-2730840 https://reactome.org/PathwayBrowser/#/R-SSC-2730840 Activation of RAC1 by VAV IEA Sus scrofa A0A286ZQX2 R-SSC-2730841 https://reactome.org/PathwayBrowser/#/R-SSC-2730841 Phosphorylation and activation of VAV IEA Sus scrofa A0A286ZQX2 R-SSC-2730847 https://reactome.org/PathwayBrowser/#/R-SSC-2730847 Hydrolysis of PIP2 by PLCG IEA Sus scrofa A0A286ZQX2 R-SSC-2730856 https://reactome.org/PathwayBrowser/#/R-SSC-2730856 Autophosphorylation of PAK IEA Sus scrofa A0A286ZQX2 R-SSC-2730858 https://reactome.org/PathwayBrowser/#/R-SSC-2730858 Autophosphorylation of BTK/ITK IEA Sus scrofa A0A286ZQX2 R-SSC-2730889 https://reactome.org/PathwayBrowser/#/R-SSC-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Sus scrofa A0A286ZQX2 R-SSC-2730892 https://reactome.org/PathwayBrowser/#/R-SSC-2730892 Recruitment of VAV to p-SLP-76 IEA Sus scrofa A0A286ZQX2 R-SSC-389348 https://reactome.org/PathwayBrowser/#/R-SSC-389348 Activation of Rac1 by pVav1 IEA Sus scrofa A0A286ZQX2 R-SSC-389350 https://reactome.org/PathwayBrowser/#/R-SSC-389350 Activation of Cdc42 by pVav1 IEA Sus scrofa A0A286ZQX2 R-SSC-389352 https://reactome.org/PathwayBrowser/#/R-SSC-389352 Translocation of Vav1 to CD28 IEA Sus scrofa A0A286ZQX2 R-SSC-389354 https://reactome.org/PathwayBrowser/#/R-SSC-389354 Activation of Vav1 IEA Sus scrofa A0A286ZQX2 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa A0A286ZQX2 R-SSC-430158 https://reactome.org/PathwayBrowser/#/R-SSC-430158 p-SLP-76 binds VAV IEA Sus scrofa A0A286ZQX2 R-SSC-442273 https://reactome.org/PathwayBrowser/#/R-SSC-442273 VAV1 is a GEF for Rho/Rac family GTPases IEA Sus scrofa A0A286ZQX2 R-SSC-5218820 https://reactome.org/PathwayBrowser/#/R-SSC-5218820 Src kinases phosphorylate VAV IEA Sus scrofa A0A286ZQX2 R-SSC-5218850 https://reactome.org/PathwayBrowser/#/R-SSC-5218850 VAV exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa A0A286ZQX2 R-SSC-5357445 https://reactome.org/PathwayBrowser/#/R-SSC-5357445 PAK1-3 dimer disassociates IEA Sus scrofa A0A286ZQX2 R-SSC-5357472 https://reactome.org/PathwayBrowser/#/R-SSC-5357472 PAK1-3 autophosphorylates IEA Sus scrofa A0A286ZQX2 R-SSC-5357483 https://reactome.org/PathwayBrowser/#/R-SSC-5357483 RAC1 binds PAK1-3 IEA Sus scrofa A0A286ZQX2 R-SSC-879914 https://reactome.org/PathwayBrowser/#/R-SSC-879914 IL3 stimulation induces Vav binding to Tec kinase IEA Sus scrofa A0A286ZQX2 R-SSC-8951586 https://reactome.org/PathwayBrowser/#/R-SSC-8951586 p-VAV family:PIP3 binds RAC1:GDP IEA Sus scrofa A0A286ZQX2 R-SSC-8980691 https://reactome.org/PathwayBrowser/#/R-SSC-8980691 RHOA GEFs activate RHOA IEA Sus scrofa A0A286ZQX2 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A286ZQX2 R-SSC-9014296 https://reactome.org/PathwayBrowser/#/R-SSC-9014296 RAC2 GEFs activate RAC2 IEA Sus scrofa A0A286ZQX2 R-SSC-9014433 https://reactome.org/PathwayBrowser/#/R-SSC-9014433 RHOG GEFs activate RHOG IEA Sus scrofa A0A286ZQX2 R-SSC-9029150 https://reactome.org/PathwayBrowser/#/R-SSC-9029150 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:phospho-SHC1 binds GRB2:VAV1 IEA Sus scrofa A0A286ZQX2 R-SSC-912727 https://reactome.org/PathwayBrowser/#/R-SSC-912727 CBL binds VAV IEA Sus scrofa A0A286ZQX2 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A286ZQX2 R-SSC-9606887 https://reactome.org/PathwayBrowser/#/R-SSC-9606887 p-CD19:VAV binds PI3K and GRB2 IEA Sus scrofa A0A286ZQX2 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A286ZQX2 R-SSC-9751201 https://reactome.org/PathwayBrowser/#/R-SSC-9751201 p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 IEA Sus scrofa A0A286ZQX5 R-SSC-75851 https://reactome.org/PathwayBrowser/#/R-SSC-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa A0A286ZQX5 R-SSC-8866941 https://reactome.org/PathwayBrowser/#/R-SSC-8866941 MID1IP1 binds THRSP IEA Sus scrofa A0A286ZQX5 R-SSC-8876889 https://reactome.org/PathwayBrowser/#/R-SSC-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa A0A286ZQY7 R-SSC-9749505 https://reactome.org/PathwayBrowser/#/R-SSC-9749505 LRRC14 binds IKBKB and CHUK IEA Sus scrofa A0A286ZQY9 R-SSC-199803 https://reactome.org/PathwayBrowser/#/R-SSC-199803 RPE dimers isomerize XY5P to RU5P IEA Sus scrofa A0A286ZQY9 R-SSC-71303 https://reactome.org/PathwayBrowser/#/R-SSC-71303 RPE dimers isomerise RU5P to XY5P IEA Sus scrofa A0A286ZQZ4 R-SSC-880050 https://reactome.org/PathwayBrowser/#/R-SSC-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 IEA Sus scrofa A0A286ZR00 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A286ZR00 R-SSC-390912 https://reactome.org/PathwayBrowser/#/R-SSC-390912 HRH1 binds hist IEA Sus scrofa A0A286ZR00 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A286ZR00 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A286ZR00 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa A0A286ZR05 R-SSC-8848355 https://reactome.org/PathwayBrowser/#/R-SSC-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Sus scrofa A0A286ZR11 R-SSC-428185 https://reactome.org/PathwayBrowser/#/R-SSC-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Sus scrofa A0A286ZR19 R-SSC-1605768 https://reactome.org/PathwayBrowser/#/R-SSC-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Sus scrofa A0A286ZR19 R-SSC-4084994 https://reactome.org/PathwayBrowser/#/R-SSC-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa A0A286ZR23 R-SSC-373061 https://reactome.org/PathwayBrowser/#/R-SSC-373061 Receptors CCR3, 4 and 5 bind CCL5 ligand IEA Sus scrofa A0A286ZR23 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A286ZR23 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A286ZR23 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A286ZR45 R-SSC-201608 https://reactome.org/PathwayBrowser/#/R-SSC-201608 Caspase-mediated cleavage of alpha adducin IEA Sus scrofa A0A286ZR45 R-SSC-5226979 https://reactome.org/PathwayBrowser/#/R-SSC-5226979 ADD1:ADD2 binds DMTN IEA Sus scrofa A0A286ZR45 R-SSC-5226999 https://reactome.org/PathwayBrowser/#/R-SSC-5226999 ADD1:ADD3 binds DMTN IEA Sus scrofa A0A286ZR76 R-SSC-1676048 https://reactome.org/PathwayBrowser/#/R-SSC-1676048 PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane IEA Sus scrofa A0A286ZR76 R-SSC-1676109 https://reactome.org/PathwayBrowser/#/R-SSC-1676109 PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane IEA Sus scrofa A0A286ZR76 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZR76 R-SSC-388830 https://reactome.org/PathwayBrowser/#/R-SSC-388830 PI3K binds ICOS IEA Sus scrofa A0A286ZR76 R-SSC-388832 https://reactome.org/PathwayBrowser/#/R-SSC-388832 PI3K binds CD28 IEA Sus scrofa A0A286ZR76 R-SSC-389158 https://reactome.org/PathwayBrowser/#/R-SSC-389158 CD28 bound PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZR76 R-SSC-392295 https://reactome.org/PathwayBrowser/#/R-SSC-392295 Gbeta:gamma recruits PI3K gamma IEA Sus scrofa A0A286ZR76 R-SSC-392300 https://reactome.org/PathwayBrowser/#/R-SSC-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Sus scrofa A0A286ZR76 R-SSC-437118 https://reactome.org/PathwayBrowser/#/R-SSC-437118 GPVI stimulates PI3K beta, gamma IEA Sus scrofa A0A286ZR76 R-SSC-437162 https://reactome.org/PathwayBrowser/#/R-SSC-437162 PI3K alpha, beta, gamma convert PIP2 to PIP3 IEA Sus scrofa A0A286ZR76 R-SSC-9012657 https://reactome.org/PathwayBrowser/#/R-SSC-9012657 EPO:phospho-EPOR:phospho-JAK2:LYN:phospho-IRS2 binds PI3K IEA Sus scrofa A0A286ZR76 R-SSC-9021627 https://reactome.org/PathwayBrowser/#/R-SSC-9021627 EPOR-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZR76 R-SSC-9027275 https://reactome.org/PathwayBrowser/#/R-SSC-9027275 EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-GAB1 binds PI3K IEA Sus scrofa A0A286ZR77 R-SSC-444007 https://reactome.org/PathwayBrowser/#/R-SSC-444007 GAT1-3 mediate Na+/Cl- dependent GABA transport IEA Sus scrofa A0A286ZR95 R-SSC-1675795 https://reactome.org/PathwayBrowser/#/R-SSC-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Sus scrofa A0A286ZR95 R-SSC-1675994 https://reactome.org/PathwayBrowser/#/R-SSC-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Sus scrofa A0A286ZR95 R-SSC-1676065 https://reactome.org/PathwayBrowser/#/R-SSC-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Sus scrofa A0A286ZR95 R-SSC-1676105 https://reactome.org/PathwayBrowser/#/R-SSC-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Sus scrofa A0A286ZR95 R-SSC-1676141 https://reactome.org/PathwayBrowser/#/R-SSC-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Sus scrofa A0A286ZR95 R-SSC-1676203 https://reactome.org/PathwayBrowser/#/R-SSC-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Sus scrofa A0A286ZR95 R-SSC-6809680 https://reactome.org/PathwayBrowser/#/R-SSC-6809680 MTMR12 binds MTM1 IEA Sus scrofa A0A286ZR95 R-SSC-6809720 https://reactome.org/PathwayBrowser/#/R-SSC-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Sus scrofa A0A286ZRB2 R-SSC-5696600 https://reactome.org/PathwayBrowser/#/R-SSC-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Sus scrofa A0A286ZRB2 R-SSC-6782820 https://reactome.org/PathwayBrowser/#/R-SSC-6782820 USP17 deubiquitinates SUDS3 IEA Sus scrofa A0A286ZRB2 R-SSC-9653514 https://reactome.org/PathwayBrowser/#/R-SSC-9653514 USP17L2 deubiquitinates RCE1 IEA Sus scrofa A0A286ZRB6 R-SSC-158546 https://reactome.org/PathwayBrowser/#/R-SSC-158546 UGTs glucuronate APAP to APAP-GlcA IEA Sus scrofa A0A286ZRB6 R-SSC-9758661 https://reactome.org/PathwayBrowser/#/R-SSC-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Sus scrofa A0A286ZRC0 R-SSC-1362261 https://reactome.org/PathwayBrowser/#/R-SSC-1362261 p130 (RBL2) associates with MuvB to form DREAM complex IEA Sus scrofa A0A286ZRC0 R-SSC-1362270 https://reactome.org/PathwayBrowser/#/R-SSC-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Sus scrofa A0A286ZRD1 R-SSC-3132737 https://reactome.org/PathwayBrowser/#/R-SSC-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Sus scrofa A0A286ZRD9 R-SSC-5159245 https://reactome.org/PathwayBrowser/#/R-SSC-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Sus scrofa A0A286ZRD9 R-SSC-5244692 https://reactome.org/PathwayBrowser/#/R-SSC-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Sus scrofa A0A286ZRD9 R-SSC-5637686 https://reactome.org/PathwayBrowser/#/R-SSC-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Sus scrofa A0A286ZRD9 R-SSC-8865482 https://reactome.org/PathwayBrowser/#/R-SSC-8865482 KMT2A (MLL) binds RUNX1 IEA Sus scrofa A0A286ZRD9 R-SSC-8936481 https://reactome.org/PathwayBrowser/#/R-SSC-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Sus scrofa A0A286ZRD9 R-SSC-8936621 https://reactome.org/PathwayBrowser/#/R-SSC-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Sus scrofa A0A286ZRD9 R-SSC-8937016 https://reactome.org/PathwayBrowser/#/R-SSC-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Sus scrofa A0A286ZRD9 R-SSC-8937050 https://reactome.org/PathwayBrowser/#/R-SSC-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Sus scrofa A0A286ZRD9 R-SSC-9675026 https://reactome.org/PathwayBrowser/#/R-SSC-9675026 Formation of the MLL1 complex IEA Sus scrofa A0A286ZRD9 R-SSC-9818574 https://reactome.org/PathwayBrowser/#/R-SSC-9818574 TASP1 cleaves KMT2A IEA Sus scrofa A0A286ZRD9 R-SSC-9818576 https://reactome.org/PathwayBrowser/#/R-SSC-9818576 Cleaved KMT2A dimers translocate to the nucleus IEA Sus scrofa A0A286ZRD9 R-SSC-9818937 https://reactome.org/PathwayBrowser/#/R-SSC-9818937 MEN1 binds MLL1 complex IEA Sus scrofa A0A286ZRD9 R-SSC-9818954 https://reactome.org/PathwayBrowser/#/R-SSC-9818954 PSIP1 binds MLL1 and MEN1 IEA Sus scrofa A0A286ZRD9 R-SSC-9821235 https://reactome.org/PathwayBrowser/#/R-SSC-9821235 HCFC1, HCFC2 bind the MLL1:MEN1 complex IEA Sus scrofa A0A286ZRD9 R-SSC-9821368 https://reactome.org/PathwayBrowser/#/R-SSC-9821368 AKAP8L binds MLL1 complex IEA Sus scrofa A0A286ZRE5 R-SSC-374758 https://reactome.org/PathwayBrowser/#/R-SSC-374758 Somatostatin receptors bind somatostatin and cortistatin IEA Sus scrofa A0A286ZRE5 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A286ZRE5 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A286ZRE5 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A286ZRE6 R-SSC-442661 https://reactome.org/PathwayBrowser/#/R-SSC-442661 SLC41A1,2 transport Mg2+ from extracellular region to cytosol IEA Sus scrofa A0A286ZRF3 R-SSC-159001 https://reactome.org/PathwayBrowser/#/R-SSC-159001 urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 2 (PAI-2) -> PAI-2:urokinase plasminogen activator (two-chain):uPAR IEA Sus scrofa A0A286ZRF3 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A286ZRF3 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A286ZRF3 R-SSC-6800426 https://reactome.org/PathwayBrowser/#/R-SSC-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Sus scrofa A0A286ZRF6 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A286ZRH5 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A286ZRH9 R-SSC-199093 https://reactome.org/PathwayBrowser/#/R-SSC-199093 CXADR binds to AMICA1 IEA Sus scrofa A0A286ZRI8 R-SSC-1606789 https://reactome.org/PathwayBrowser/#/R-SSC-1606789 ARSB hydrolyses DS IEA Sus scrofa A0A286ZRI8 R-SSC-1614362 https://reactome.org/PathwayBrowser/#/R-SSC-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Sus scrofa A0A286ZRI8 R-SSC-1793207 https://reactome.org/PathwayBrowser/#/R-SSC-1793207 ARSB hydrolyses C4S/C6S chains IEA Sus scrofa A0A286ZRI8 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A286ZRI8 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A286ZRJ3 R-SSC-169260 https://reactome.org/PathwayBrowser/#/R-SSC-169260 Reducing equivalents from beta-oxidation of fatty acids transfer to ETF IEA Sus scrofa A0A286ZRJ3 R-SSC-169270 https://reactome.org/PathwayBrowser/#/R-SSC-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 IEA Sus scrofa A0A286ZRJ8 R-SSC-8954262 https://reactome.org/PathwayBrowser/#/R-SSC-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 IEA Sus scrofa A0A286ZRL1 R-SSC-9838035 https://reactome.org/PathwayBrowser/#/R-SSC-9838035 CLPXP binds mitochondrial matrix proteins IEA Sus scrofa A0A286ZRL1 R-SSC-9838289 https://reactome.org/PathwayBrowser/#/R-SSC-9838289 CLPXP degrades mitochondrial matrix proteins IEA Sus scrofa A0A286ZRM0 R-SSC-3229089 https://reactome.org/PathwayBrowser/#/R-SSC-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Sus scrofa A0A286ZRM0 R-SSC-3229102 https://reactome.org/PathwayBrowser/#/R-SSC-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Sus scrofa A0A286ZRM0 R-SSC-8937989 https://reactome.org/PathwayBrowser/#/R-SSC-8937989 RUNX1 binds PRC1 complexes IEA Sus scrofa A0A286ZRM0 R-SSC-8943817 https://reactome.org/PathwayBrowser/#/R-SSC-8943817 MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter IEA Sus scrofa A0A286ZRP0 R-SSC-8876188 https://reactome.org/PathwayBrowser/#/R-SSC-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Sus scrofa A0A286ZRQ0 R-SSC-3858482 https://reactome.org/PathwayBrowser/#/R-SSC-3858482 DVL is recruited to the receptor IEA Sus scrofa A0A286ZRQ0 R-SSC-3965444 https://reactome.org/PathwayBrowser/#/R-SSC-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Sus scrofa A0A286ZRQ0 R-SSC-3965447 https://reactome.org/PathwayBrowser/#/R-SSC-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Sus scrofa A0A286ZRQ0 R-SSC-5099886 https://reactome.org/PathwayBrowser/#/R-SSC-5099886 WNT5A binding to FZD promotes PRICKLE1 degradation IEA Sus scrofa A0A286ZRS0 R-SSC-174394 https://reactome.org/PathwayBrowser/#/R-SSC-174394 GSS:Mg2+ dimer synthesizes GSH IEA Sus scrofa A0A286ZRS6 R-SSC-9760402 https://reactome.org/PathwayBrowser/#/R-SSC-9760402 ILF3 binds HOXC8 IEA Sus scrofa A0A286ZRT5 R-SSC-8949649 https://reactome.org/PathwayBrowser/#/R-SSC-8949649 PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) IEA Sus scrofa A0A286ZRT5 R-SSC-9838081 https://reactome.org/PathwayBrowser/#/R-SSC-9838081 LONP1 degrades mitochondrial matrix proteins IEA Sus scrofa A0A286ZRT5 R-SSC-9838093 https://reactome.org/PathwayBrowser/#/R-SSC-9838093 LONP1 binds mitochondrial matrix proteins IEA Sus scrofa A0A286ZRT7 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A286ZRT7 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A286ZRT7 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A286ZRT7 R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa A0A286ZRT7 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa A0A286ZRU9 R-SSC-2089971 https://reactome.org/PathwayBrowser/#/R-SSC-2089971 Secretion of collagens IEA Sus scrofa A0A286ZRX0 R-SSC-6799777 https://reactome.org/PathwayBrowser/#/R-SSC-6799777 TP53 family members bind PPP1R13B or TP53BP2 IEA Sus scrofa A0A286ZRX5 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A286ZRY1 R-SSC-5690023 https://reactome.org/PathwayBrowser/#/R-SSC-5690023 NUBPL binds 4Fe-4S IEA Sus scrofa A0A286ZRY1 R-SSC-6788523 https://reactome.org/PathwayBrowser/#/R-SSC-6788523 NUBPL transfers 4Fe-4S to Complex I subunits IEA Sus scrofa A0A286ZRY1 R-SSC-6788556 https://reactome.org/PathwayBrowser/#/R-SSC-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Sus scrofa A0A286ZRY7 R-SSC-164832 https://reactome.org/PathwayBrowser/#/R-SSC-164832 ATPase synthesizes ATP IEA Sus scrofa A0A286ZRY7 R-SSC-164834 https://reactome.org/PathwayBrowser/#/R-SSC-164834 Enzyme-bound ATP is released IEA Sus scrofa A0A286ZRY7 R-SSC-164840 https://reactome.org/PathwayBrowser/#/R-SSC-164840 ADP and Pi bind to ATPase IEA Sus scrofa A0A286ZRY7 R-SSC-8949580 https://reactome.org/PathwayBrowser/#/R-SSC-8949580 F1Fo ATP synthase dimerizes IEA Sus scrofa A0A286ZRZ7 R-SSC-448958 https://reactome.org/PathwayBrowser/#/R-SSC-448958 Nuclear translocation of p38 MAPK IEA Sus scrofa A0A286ZS01 R-SSC-3108212 https://reactome.org/PathwayBrowser/#/R-SSC-3108212 SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 IEA Sus scrofa A0A286ZS02 R-SSC-481009 https://reactome.org/PathwayBrowser/#/R-SSC-481009 Exocytosis of platelet dense granule content IEA Sus scrofa A0A286ZS23 R-SSC-8849638 https://reactome.org/PathwayBrowser/#/R-SSC-8849638 Dissociation of the SPINK5:KLK5 complex at low pH IEA Sus scrofa A0A286ZS23 R-SSC-8849646 https://reactome.org/PathwayBrowser/#/R-SSC-8849646 SPINK5(490-624) binds KLK5 IEA Sus scrofa A0A286ZS23 R-SSC-8849857 https://reactome.org/PathwayBrowser/#/R-SSC-8849857 KLK5 cleaves and activates CELA2 IEA Sus scrofa A0A286ZS23 R-SSC-8850794 https://reactome.org/PathwayBrowser/#/R-SSC-8850794 SPINK6 binds KLK5 IEA Sus scrofa A0A286ZS23 R-SSC-8850818 https://reactome.org/PathwayBrowser/#/R-SSC-8850818 SPINK9 binds KLK5 IEA Sus scrofa A0A286ZS23 R-SSC-8850831 https://reactome.org/PathwayBrowser/#/R-SSC-8850831 KLK5 cleaves and activates KLK8 IEA Sus scrofa A0A286ZS25 R-SSC-5607720 https://reactome.org/PathwayBrowser/#/R-SSC-5607720 p100:RELB binds active NIK:p-IKKA dimer IEA Sus scrofa A0A286ZS25 R-SSC-5607726 https://reactome.org/PathwayBrowser/#/R-SSC-5607726 Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB IEA Sus scrofa A0A286ZS25 R-SSC-5607731 https://reactome.org/PathwayBrowser/#/R-SSC-5607731 26S proteasome processes p-7S-p100:RELB to form p52:RELB IEA Sus scrofa A0A286ZS25 R-SSC-5607741 https://reactome.org/PathwayBrowser/#/R-SSC-5607741 p52:RELB translocates from cytosol to nucleus IEA Sus scrofa A0A286ZS25 R-SSC-5660980 https://reactome.org/PathwayBrowser/#/R-SSC-5660980 p-S276-RELA binds RELB IEA Sus scrofa A0A286ZS27 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A286ZS27 R-SSC-8854222 https://reactome.org/PathwayBrowser/#/R-SSC-8854222 TBC1D3 associates with RAB5 IEA Sus scrofa A0A286ZS27 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A286ZS27 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A286ZS27 R-SSC-8875320 https://reactome.org/PathwayBrowser/#/R-SSC-8875320 RAB5 GEFs exchange GTP for GDP on RAB5 IEA Sus scrofa A0A286ZS31 R-SSC-71296 https://reactome.org/PathwayBrowser/#/R-SSC-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Sus scrofa A0A286ZS33 R-SSC-2997616 https://reactome.org/PathwayBrowser/#/R-SSC-2997616 PIAS1,4 SUMOylates BRCA1 with SUMO2,3 IEA Sus scrofa A0A286ZS33 R-SSC-2997709 https://reactome.org/PathwayBrowser/#/R-SSC-2997709 PIAS1,4 SUMOylates BRCA1 with SUMO1 IEA Sus scrofa A0A286ZS33 R-SSC-5659781 https://reactome.org/PathwayBrowser/#/R-SSC-5659781 BRCA1 forms a heterodimer with BARD1 IEA Sus scrofa A0A286ZS33 R-SSC-5683385 https://reactome.org/PathwayBrowser/#/R-SSC-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Sus scrofa A0A286ZS33 R-SSC-5683735 https://reactome.org/PathwayBrowser/#/R-SSC-5683735 CHEK2 is recruited to DNA DSBs IEA Sus scrofa A0A286ZS33 R-SSC-5683801 https://reactome.org/PathwayBrowser/#/R-SSC-5683801 CHEK2 phosphorylates BRCA1 IEA Sus scrofa A0A286ZS33 R-SSC-5684052 https://reactome.org/PathwayBrowser/#/R-SSC-5684052 PIAS4 SUMOylates MDC1 IEA Sus scrofa A0A286ZS33 R-SSC-5684108 https://reactome.org/PathwayBrowser/#/R-SSC-5684108 BRCA1 binds phosphorylated RBBP8 IEA Sus scrofa A0A286ZS33 R-SSC-5684875 https://reactome.org/PathwayBrowser/#/R-SSC-5684875 Binding of ATR:ATRIP to RPA at resected DNA DSBs IEA Sus scrofa A0A286ZS33 R-SSC-5684882 https://reactome.org/PathwayBrowser/#/R-SSC-5684882 CHEK1 is recruited to resected DNA DSBs IEA Sus scrofa A0A286ZS33 R-SSC-5684887 https://reactome.org/PathwayBrowser/#/R-SSC-5684887 Activation of CHEK1 at resected DNA DSBs IEA Sus scrofa A0A286ZS33 R-SSC-5685011 https://reactome.org/PathwayBrowser/#/R-SSC-5685011 ATR activation at DNA DSBs IEA Sus scrofa A0A286ZS33 R-SSC-5685156 https://reactome.org/PathwayBrowser/#/R-SSC-5685156 ATR phosphorylates RPA2 IEA Sus scrofa A0A286ZS33 R-SSC-5685341 https://reactome.org/PathwayBrowser/#/R-SSC-5685341 BCDX2 complex stabilizes RAD51 filament IEA Sus scrofa A0A286ZS33 R-SSC-5685838 https://reactome.org/PathwayBrowser/#/R-SSC-5685838 CX3 complex binds D-loop structures IEA Sus scrofa A0A286ZS33 R-SSC-5685985 https://reactome.org/PathwayBrowser/#/R-SSC-5685985 EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment IEA Sus scrofa A0A286ZS33 R-SSC-5685994 https://reactome.org/PathwayBrowser/#/R-SSC-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Sus scrofa A0A286ZS33 R-SSC-5686440 https://reactome.org/PathwayBrowser/#/R-SSC-5686440 MUS81:EME1,EME2 cleaves D-loop IEA Sus scrofa A0A286ZS33 R-SSC-5686642 https://reactome.org/PathwayBrowser/#/R-SSC-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Sus scrofa A0A286ZS33 R-SSC-5686657 https://reactome.org/PathwayBrowser/#/R-SSC-5686657 ERCC1:XPF cleaves flaps generated by SSA IEA Sus scrofa A0A286ZS33 R-SSC-5686685 https://reactome.org/PathwayBrowser/#/R-SSC-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Sus scrofa A0A286ZS33 R-SSC-5691411 https://reactome.org/PathwayBrowser/#/R-SSC-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Sus scrofa A0A286ZS33 R-SSC-5693539 https://reactome.org/PathwayBrowser/#/R-SSC-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Sus scrofa A0A286ZS33 R-SSC-5693542 https://reactome.org/PathwayBrowser/#/R-SSC-5693542 Association of RPA complexes with ssDNA at resected DNA DSBs IEA Sus scrofa A0A286ZS33 R-SSC-5693551 https://reactome.org/PathwayBrowser/#/R-SSC-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Sus scrofa A0A286ZS33 R-SSC-5693564 https://reactome.org/PathwayBrowser/#/R-SSC-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Sus scrofa A0A286ZS33 R-SSC-5693580 https://reactome.org/PathwayBrowser/#/R-SSC-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Sus scrofa A0A286ZS33 R-SSC-5693584 https://reactome.org/PathwayBrowser/#/R-SSC-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Sus scrofa A0A286ZS33 R-SSC-5693593 https://reactome.org/PathwayBrowser/#/R-SSC-5693593 D-loop extension by DNA polymerases IEA Sus scrofa A0A286ZS33 R-SSC-5693608 https://reactome.org/PathwayBrowser/#/R-SSC-5693608 Initial resection of double-strand break ends IEA Sus scrofa A0A286ZS33 R-SSC-5693620 https://reactome.org/PathwayBrowser/#/R-SSC-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Sus scrofa A0A286ZS33 R-SSC-6799332 https://reactome.org/PathwayBrowser/#/R-SSC-6799332 ATR phosphorylates TP53 IEA Sus scrofa A0A286ZS33 R-SSC-69891 https://reactome.org/PathwayBrowser/#/R-SSC-69891 Phosphorylation and activation of CHEK2 by ATM IEA Sus scrofa A0A286ZS33 R-SSC-9700998 https://reactome.org/PathwayBrowser/#/R-SSC-9700998 BAP1 disrupts the BRCA1:BARD1 heterodimer IEA Sus scrofa A0A286ZS33 R-SSC-9701000 https://reactome.org/PathwayBrowser/#/R-SSC-9701000 BRCA1:BARD1 heterodimer autoubiquitinates IEA Sus scrofa A0A286ZS33 R-SSC-9701003 https://reactome.org/PathwayBrowser/#/R-SSC-9701003 BAP1 binds BRCA1:BARD1 heterodimer IEA Sus scrofa A0A286ZS33 R-SSC-9707051 https://reactome.org/PathwayBrowser/#/R-SSC-9707051 UBXN1 binds BRCA1:BARD1 heterodimer IEA Sus scrofa A0A286ZS33 R-SSC-9853389 https://reactome.org/PathwayBrowser/#/R-SSC-9853389 FIGNL1 binds RAD51 IEA Sus scrofa A0A286ZS34 R-SSC-1168640 https://reactome.org/PathwayBrowser/#/R-SSC-1168640 Ubiquitinated IkB is degraded IEA Sus scrofa A0A286ZS34 R-SSC-1234159 https://reactome.org/PathwayBrowser/#/R-SSC-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Sus scrofa A0A286ZS34 R-SSC-1236970 https://reactome.org/PathwayBrowser/#/R-SSC-1236970 Proteasomal clevage of exogenous antigen (26S proteasome catalyst) IEA Sus scrofa A0A286ZS34 R-SSC-1504193 https://reactome.org/PathwayBrowser/#/R-SSC-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Sus scrofa A0A286ZS34 R-SSC-174058 https://reactome.org/PathwayBrowser/#/R-SSC-174058 Degradation of multiubiquitinated Cdh1 IEA Sus scrofa A0A286ZS34 R-SSC-174105 https://reactome.org/PathwayBrowser/#/R-SSC-174105 Degradation of multiubiquitinated cell cycle proteins IEA Sus scrofa A0A286ZS34 R-SSC-174202 https://reactome.org/PathwayBrowser/#/R-SSC-174202 Degradation of multiubiquitinated Securin IEA Sus scrofa A0A286ZS34 R-SSC-174255 https://reactome.org/PathwayBrowser/#/R-SSC-174255 Degradation multiubiquitinated Cyclin A IEA Sus scrofa A0A286ZS34 R-SSC-187574 https://reactome.org/PathwayBrowser/#/R-SSC-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Sus scrofa A0A286ZS34 R-SSC-188191 https://reactome.org/PathwayBrowser/#/R-SSC-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Sus scrofa A0A286ZS34 R-SSC-209061 https://reactome.org/PathwayBrowser/#/R-SSC-209061 Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex IEA Sus scrofa A0A286ZS34 R-SSC-2130282 https://reactome.org/PathwayBrowser/#/R-SSC-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Sus scrofa A0A286ZS34 R-SSC-264458 https://reactome.org/PathwayBrowser/#/R-SSC-264458 Proteasome mediated degradation of COP1 IEA Sus scrofa A0A286ZS34 R-SSC-353125 https://reactome.org/PathwayBrowser/#/R-SSC-353125 26S proteosome degrades ODC holoenzyme complex IEA Sus scrofa A0A286ZS34 R-SSC-3640874 https://reactome.org/PathwayBrowser/#/R-SSC-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Sus scrofa A0A286ZS34 R-SSC-450466 https://reactome.org/PathwayBrowser/#/R-SSC-450466 AUF1:mRNA complex is destroyed IEA Sus scrofa A0A286ZS34 R-SSC-4608855 https://reactome.org/PathwayBrowser/#/R-SSC-4608855 PRICKLE1 is degraded by the proteasome IEA Sus scrofa A0A286ZS34 R-SSC-4641256 https://reactome.org/PathwayBrowser/#/R-SSC-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Sus scrofa A0A286ZS34 R-SSC-4641260 https://reactome.org/PathwayBrowser/#/R-SSC-4641260 Ubiquitinated DVL1 is degraded by the proteasome IEA Sus scrofa A0A286ZS34 R-SSC-5362448 https://reactome.org/PathwayBrowser/#/R-SSC-5362448 Hh C-terminal fragments are degraded by the proteasome IEA Sus scrofa A0A286ZS34 R-SSC-5607724 https://reactome.org/PathwayBrowser/#/R-SSC-5607724 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex IEA Sus scrofa A0A286ZS34 R-SSC-5607731 https://reactome.org/PathwayBrowser/#/R-SSC-5607731 26S proteasome processes p-7S-p100:RELB to form p52:RELB IEA Sus scrofa A0A286ZS34 R-SSC-5610754 https://reactome.org/PathwayBrowser/#/R-SSC-5610754 GLI3 is partially degraded by the proteasome to yield the GLI3 repressor IEA Sus scrofa A0A286ZS34 R-SSC-5610758 https://reactome.org/PathwayBrowser/#/R-SSC-5610758 GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP IEA Sus scrofa A0A286ZS34 R-SSC-5610760 https://reactome.org/PathwayBrowser/#/R-SSC-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Sus scrofa A0A286ZS34 R-SSC-5635854 https://reactome.org/PathwayBrowser/#/R-SSC-5635854 GLI2,3 are degraded by the proteasome IEA Sus scrofa A0A286ZS34 R-SSC-5635868 https://reactome.org/PathwayBrowser/#/R-SSC-5635868 ub-GLI is degraded by the proteasome IEA Sus scrofa A0A286ZS34 R-SSC-5658430 https://reactome.org/PathwayBrowser/#/R-SSC-5658430 NF1 is degraded by the proteasome IEA Sus scrofa A0A286ZS34 R-SSC-5665854 https://reactome.org/PathwayBrowser/#/R-SSC-5665854 ADRM1:26S proteaseome binds UCHL5 IEA Sus scrofa A0A286ZS34 R-SSC-5665871 https://reactome.org/PathwayBrowser/#/R-SSC-5665871 ADRM1 binds 26S proteasome IEA Sus scrofa A0A286ZS34 R-SSC-5668481 https://reactome.org/PathwayBrowser/#/R-SSC-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Sus scrofa A0A286ZS34 R-SSC-5668520 https://reactome.org/PathwayBrowser/#/R-SSC-5668520 26Sproteasome degrades K48polyUb-NIK IEA Sus scrofa A0A286ZS34 R-SSC-5687112 https://reactome.org/PathwayBrowser/#/R-SSC-5687112 MAPK6 is degraded by the 26S proteasome IEA Sus scrofa A0A286ZS34 R-SSC-5689539 https://reactome.org/PathwayBrowser/#/R-SSC-5689539 ADRM1:26S proteaseome binds USP14 IEA Sus scrofa A0A286ZS34 R-SSC-68825 https://reactome.org/PathwayBrowser/#/R-SSC-68825 Ubiquitinated geminin is degraded by the proteasome IEA Sus scrofa A0A286ZS34 R-SSC-68948 https://reactome.org/PathwayBrowser/#/R-SSC-68948 Ubiquitinated Orc1 is degraded by the proteasome IEA Sus scrofa A0A286ZS34 R-SSC-69016 https://reactome.org/PathwayBrowser/#/R-SSC-69016 Ubiquitinated Cdc6 is degraded by the proteasome IEA Sus scrofa A0A286ZS34 R-SSC-69600 https://reactome.org/PathwayBrowser/#/R-SSC-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Sus scrofa A0A286ZS34 R-SSC-75825 https://reactome.org/PathwayBrowser/#/R-SSC-75825 Proteasome mediated degradation of Cyclin D1 IEA Sus scrofa A0A286ZS34 R-SSC-8850992 https://reactome.org/PathwayBrowser/#/R-SSC-8850992 Proteasome degrades polyubiquitinated PTEN IEA Sus scrofa A0A286ZS34 R-SSC-8852354 https://reactome.org/PathwayBrowser/#/R-SSC-8852354 GTSE1 facilitates proteasome-mediated degradation of TP53 IEA Sus scrofa A0A286ZS34 R-SSC-8854044 https://reactome.org/PathwayBrowser/#/R-SSC-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Sus scrofa A0A286ZS34 R-SSC-8854071 https://reactome.org/PathwayBrowser/#/R-SSC-8854071 Proteasome-mediated degradation of PolyUb-FBXL7 IEA Sus scrofa A0A286ZS34 R-SSC-8866553 https://reactome.org/PathwayBrowser/#/R-SSC-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Sus scrofa A0A286ZS34 R-SSC-8932355 https://reactome.org/PathwayBrowser/#/R-SSC-8932355 26S proteasome degrades Ub-NFE2L2 IEA Sus scrofa A0A286ZS34 R-SSC-8939801 https://reactome.org/PathwayBrowser/#/R-SSC-8939801 26S proteasome degrades PolyUb-RUNX2 IEA Sus scrofa A0A286ZS34 R-SSC-8952408 https://reactome.org/PathwayBrowser/#/R-SSC-8952408 Polyubiquitinated RUNX3 is degraded by the proteasome IEA Sus scrofa A0A286ZS34 R-SSC-8956140 https://reactome.org/PathwayBrowser/#/R-SSC-8956140 NEDD8 and UBD bind NUB1 and the 26S proteasome IEA Sus scrofa A0A286ZS34 R-SSC-8956184 https://reactome.org/PathwayBrowser/#/R-SSC-8956184 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates IEA Sus scrofa A0A286ZS34 R-SSC-8957265 https://reactome.org/PathwayBrowser/#/R-SSC-8957265 26S proteasome degrades TP73 polyubiquitinated by ITCH IEA Sus scrofa A0A286ZS34 R-SSC-9755303 https://reactome.org/PathwayBrowser/#/R-SSC-9755303 26S proteasome degrades HIFalpha IEA Sus scrofa A0A286ZS34 R-SSC-9755306 https://reactome.org/PathwayBrowser/#/R-SSC-9755306 ub UBXN7 is degraded by the 26S proteasome IEA Sus scrofa A0A286ZS34 R-SSC-9762096 https://reactome.org/PathwayBrowser/#/R-SSC-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Sus scrofa A0A286ZS34 R-SSC-983150 https://reactome.org/PathwayBrowser/#/R-SSC-983150 Proteasomal cleavage of substrate IEA Sus scrofa A0A286ZS34 R-SSC-9907919 https://reactome.org/PathwayBrowser/#/R-SSC-9907919 Formation of the preholoproteasome IEA Sus scrofa A0A286ZS34 R-SSC-9908709 https://reactome.org/PathwayBrowser/#/R-SSC-9908709 Formation of the PA28-alpha-beta-20S proteasome IEA Sus scrofa A0A286ZS34 R-SSC-9908721 https://reactome.org/PathwayBrowser/#/R-SSC-9908721 Formation of the PA28gamma-20S proteasome IEA Sus scrofa A0A286ZS34 R-SSC-9912636 https://reactome.org/PathwayBrowser/#/R-SSC-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Sus scrofa A0A286ZS34 R-SSC-9934893 https://reactome.org/PathwayBrowser/#/R-SSC-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 IEA Sus scrofa A0A286ZS35 R-SSC-388828 https://reactome.org/PathwayBrowser/#/R-SSC-388828 PD-1 binds B7DC and B7H1 IEA Sus scrofa A0A286ZS35 R-SSC-389758 https://reactome.org/PathwayBrowser/#/R-SSC-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Sus scrofa A0A286ZS35 R-SSC-389759 https://reactome.org/PathwayBrowser/#/R-SSC-389759 Interaction of SHP-1 or SHP-2 with phospho PD-1 IEA Sus scrofa A0A286ZS35 R-SSC-389762 https://reactome.org/PathwayBrowser/#/R-SSC-389762 Phosphorylation of PD-1 IEA Sus scrofa A0A286ZS39 R-SSC-1667005 https://reactome.org/PathwayBrowser/#/R-SSC-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Sus scrofa A0A286ZS39 R-SSC-1678694 https://reactome.org/PathwayBrowser/#/R-SSC-1678694 Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans IEA Sus scrofa A0A286ZS39 R-SSC-1878002 https://reactome.org/PathwayBrowser/#/R-SSC-1878002 XYLTs transfer Xyl to core protein IEA Sus scrofa A0A286ZS39 R-SSC-1889955 https://reactome.org/PathwayBrowser/#/R-SSC-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Sus scrofa A0A286ZS39 R-SSC-1889978 https://reactome.org/PathwayBrowser/#/R-SSC-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Sus scrofa A0A286ZS39 R-SSC-1889981 https://reactome.org/PathwayBrowser/#/R-SSC-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Sus scrofa A0A286ZS39 R-SSC-2022851 https://reactome.org/PathwayBrowser/#/R-SSC-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Sus scrofa A0A286ZS39 R-SSC-2022856 https://reactome.org/PathwayBrowser/#/R-SSC-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Sus scrofa A0A286ZS39 R-SSC-2022860 https://reactome.org/PathwayBrowser/#/R-SSC-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Sus scrofa A0A286ZS39 R-SSC-2022887 https://reactome.org/PathwayBrowser/#/R-SSC-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Sus scrofa A0A286ZS39 R-SSC-2022919 https://reactome.org/PathwayBrowser/#/R-SSC-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Sus scrofa A0A286ZS39 R-SSC-2024084 https://reactome.org/PathwayBrowser/#/R-SSC-2024084 HS-GAGs translocate to the lysosome for degradation IEA Sus scrofa A0A286ZS39 R-SSC-2024108 https://reactome.org/PathwayBrowser/#/R-SSC-2024108 Some HSPGs are secreted to the plasma membrane IEA Sus scrofa A0A286ZS39 R-SSC-2076383 https://reactome.org/PathwayBrowser/#/R-SSC-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Sus scrofa A0A286ZS39 R-SSC-2076392 https://reactome.org/PathwayBrowser/#/R-SSC-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Sus scrofa A0A286ZS39 R-SSC-2076419 https://reactome.org/PathwayBrowser/#/R-SSC-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Sus scrofa A0A286ZS39 R-SSC-2076508 https://reactome.org/PathwayBrowser/#/R-SSC-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Sus scrofa A0A286ZS39 R-SSC-2076611 https://reactome.org/PathwayBrowser/#/R-SSC-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Sus scrofa A0A286ZS39 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa A0A286ZS39 R-SSC-2423785 https://reactome.org/PathwayBrowser/#/R-SSC-2423785 CR:atREs binds apoE and HSPG IEA Sus scrofa A0A286ZS39 R-SSC-2467665 https://reactome.org/PathwayBrowser/#/R-SSC-2467665 AGRN binds Beta amyloid fibril via GAG chains IEA Sus scrofa A0A286ZS39 R-SSC-9638064 https://reactome.org/PathwayBrowser/#/R-SSC-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Sus scrofa A0A286ZS39 R-SSC-9914537 https://reactome.org/PathwayBrowser/#/R-SSC-9914537 DGC complex binds AGRN and HSPG2 IEA Sus scrofa A0A286ZS46 R-SSC-879575 https://reactome.org/PathwayBrowser/#/R-SSC-879575 SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol IEA Sus scrofa A0A286ZS52 R-SSC-3465545 https://reactome.org/PathwayBrowser/#/R-SSC-3465545 PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 IEA Sus scrofa A0A286ZS52 R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa A0A286ZS52 R-SSC-73739 https://reactome.org/PathwayBrowser/#/R-SSC-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter IEA Sus scrofa A0A286ZS52 R-SSC-8943780 https://reactome.org/PathwayBrowser/#/R-SSC-8943780 SALL4 recruits NuRD to PTEN gene IEA Sus scrofa A0A286ZS52 R-SSC-9679787 https://reactome.org/PathwayBrowser/#/R-SSC-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Sus scrofa A0A286ZS63 R-SSC-203973 https://reactome.org/PathwayBrowser/#/R-SSC-203973 Vesicle budding IEA Sus scrofa A0A286ZS63 R-SSC-204008 https://reactome.org/PathwayBrowser/#/R-SSC-204008 SEC31:SEC13 and v-SNARE recruitment IEA Sus scrofa A0A286ZS63 R-SSC-399711 https://reactome.org/PathwayBrowser/#/R-SSC-399711 Activation of Ca impermeable AMPA receptors IEA Sus scrofa A0A286ZS63 R-SSC-399712 https://reactome.org/PathwayBrowser/#/R-SSC-399712 Activation of Ca permeable AMPA receptors IEA Sus scrofa A0A286ZS63 R-SSC-416320 https://reactome.org/PathwayBrowser/#/R-SSC-416320 Trafficking of GluR1-containing AMPA receptors IEA Sus scrofa A0A286ZS63 R-SSC-416639 https://reactome.org/PathwayBrowser/#/R-SSC-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Sus scrofa A0A286ZS63 R-SSC-416985 https://reactome.org/PathwayBrowser/#/R-SSC-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Sus scrofa A0A286ZS63 R-SSC-420975 https://reactome.org/PathwayBrowser/#/R-SSC-420975 Ca impermeable AMPA receptor ligand binding IEA Sus scrofa A0A286ZS63 R-SSC-420977 https://reactome.org/PathwayBrowser/#/R-SSC-420977 Ca permeable AMPA receptor ligand binding IEA Sus scrofa A0A286ZS63 R-SSC-420980 https://reactome.org/PathwayBrowser/#/R-SSC-420980 Activation of Ca permeable AMPA receptors IEA Sus scrofa A0A286ZS63 R-SSC-421007 https://reactome.org/PathwayBrowser/#/R-SSC-421007 Endocytosis of Ca impermeable AMPA receptors IEA Sus scrofa A0A286ZS63 R-SSC-438037 https://reactome.org/PathwayBrowser/#/R-SSC-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Sus scrofa A0A286ZS63 R-SSC-5694409 https://reactome.org/PathwayBrowser/#/R-SSC-5694409 Nucleotide exchange on RAB1 IEA Sus scrofa A0A286ZS63 R-SSC-5694417 https://reactome.org/PathwayBrowser/#/R-SSC-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Sus scrofa A0A286ZS63 R-SSC-5694418 https://reactome.org/PathwayBrowser/#/R-SSC-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Sus scrofa A0A286ZS63 R-SSC-5694442 https://reactome.org/PathwayBrowser/#/R-SSC-5694442 CNIH2,3 bind GRIA1 IEA Sus scrofa A0A286ZS63 R-SSC-5694446 https://reactome.org/PathwayBrowser/#/R-SSC-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Sus scrofa A0A286ZS63 R-SSC-5694522 https://reactome.org/PathwayBrowser/#/R-SSC-5694522 Inner coat assembly and cargo binding IEA Sus scrofa A0A286ZS63 R-SSC-5694527 https://reactome.org/PathwayBrowser/#/R-SSC-5694527 Loss of SAR1B GTPase IEA Sus scrofa A0A286ZS88 R-SSC-9837333 https://reactome.org/PathwayBrowser/#/R-SSC-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP IEA Sus scrofa A0A286ZS94 R-SSC-9750226 https://reactome.org/PathwayBrowser/#/R-SSC-9750226 NLRC5 binds IKBKB and CHUK IEA Sus scrofa A0A286ZS94 R-SSC-9750942 https://reactome.org/PathwayBrowser/#/R-SSC-9750942 USP14 deubiquitinates NLRC5 IEA Sus scrofa A0A286ZS94 R-SSC-9750946 https://reactome.org/PathwayBrowser/#/R-SSC-9750946 TRAF2,6 ubiquitinates NLRC5 IEA Sus scrofa A0A286ZS97 R-SSC-8874470 https://reactome.org/PathwayBrowser/#/R-SSC-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Sus scrofa A0A286ZSA0 R-SSC-421831 https://reactome.org/PathwayBrowser/#/R-SSC-421831 trans-Golgi Network Coat Assembly IEA Sus scrofa A0A286ZSA0 R-SSC-421835 https://reactome.org/PathwayBrowser/#/R-SSC-421835 trans-Golgi Network Vesicle Scission IEA Sus scrofa A0A286ZSB7 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A286ZSB7 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A286ZSB7 R-SSC-2466068 https://reactome.org/PathwayBrowser/#/R-SSC-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Sus scrofa A0A286ZSB7 R-SSC-2467794 https://reactome.org/PathwayBrowser/#/R-SSC-2467794 Resolution of sister chromatids IEA Sus scrofa A0A286ZSB7 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A286ZSB7 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A286ZSB7 R-SSC-2468039 https://reactome.org/PathwayBrowser/#/R-SSC-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Sus scrofa A0A286ZSB7 R-SSC-2468040 https://reactome.org/PathwayBrowser/#/R-SSC-2468040 Cohesin binds PDS5 and WAPAL IEA Sus scrofa A0A286ZSB7 R-SSC-2468041 https://reactome.org/PathwayBrowser/#/R-SSC-2468041 CDCA5 (Sororin) enables cohesion of sister chromosomal arms IEA Sus scrofa A0A286ZSB7 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A286ZSB7 R-SSC-2468293 https://reactome.org/PathwayBrowser/#/R-SSC-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Sus scrofa A0A286ZSB7 R-SSC-2470935 https://reactome.org/PathwayBrowser/#/R-SSC-2470935 Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 IEA Sus scrofa A0A286ZSB7 R-SSC-2473151 https://reactome.org/PathwayBrowser/#/R-SSC-2473151 CDCA5 (Sororin) enables cohesion of sister centromeres IEA Sus scrofa A0A286ZSB7 R-SSC-2473152 https://reactome.org/PathwayBrowser/#/R-SSC-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Sus scrofa A0A286ZSB7 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A286ZSB7 R-SSC-2545203 https://reactome.org/PathwayBrowser/#/R-SSC-2545203 Deacetylation of cleaved cohesin IEA Sus scrofa A0A286ZSB7 R-SSC-2545253 https://reactome.org/PathwayBrowser/#/R-SSC-2545253 Deacetylation of cohesin IEA Sus scrofa A0A286ZSC5 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A286ZSD7 R-SSC-9840408 https://reactome.org/PathwayBrowser/#/R-SSC-9840408 OMA1 cleaves DELE1 IEA Sus scrofa A0A286ZSF3 R-SSC-8865605 https://reactome.org/PathwayBrowser/#/R-SSC-8865605 BRWD1 binds SMARCA4 IEA Sus scrofa A0A286ZSF3 R-SSC-8865613 https://reactome.org/PathwayBrowser/#/R-SSC-8865613 BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3 IEA Sus scrofa A0A286ZSF5 R-SSC-3928578 https://reactome.org/PathwayBrowser/#/R-SSC-3928578 EPH receptors autophosphorylate IEA Sus scrofa A0A286ZSF5 R-SSC-3928591 https://reactome.org/PathwayBrowser/#/R-SSC-3928591 EPH:EFN tetramers oligomerise IEA Sus scrofa A0A286ZSF5 R-SSC-3928597 https://reactome.org/PathwayBrowser/#/R-SSC-3928597 EPH:EFN dimers tetramerise IEA Sus scrofa A0A286ZSF5 R-SSC-3928604 https://reactome.org/PathwayBrowser/#/R-SSC-3928604 SFKs phosphorylate VAV2,3 IEA Sus scrofa A0A286ZSF5 R-SSC-3928607 https://reactome.org/PathwayBrowser/#/R-SSC-3928607 p-EPHs bind VAV2,3 IEA Sus scrofa A0A286ZSF5 R-SSC-3928628 https://reactome.org/PathwayBrowser/#/R-SSC-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa A0A286ZSF5 R-SSC-3928642 https://reactome.org/PathwayBrowser/#/R-SSC-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa A0A286ZSF5 R-SSC-3928646 https://reactome.org/PathwayBrowser/#/R-SSC-3928646 EPHAs bind EFNAs IEA Sus scrofa A0A286ZSF5 R-SSC-3928651 https://reactome.org/PathwayBrowser/#/R-SSC-3928651 NGEF exchanges GTP for GDP on RHOA IEA Sus scrofa A0A286ZSF5 R-SSC-4093327 https://reactome.org/PathwayBrowser/#/R-SSC-4093327 EPHA binds TIAM1 IEA Sus scrofa A0A286ZSG4 R-SSC-6791221 https://reactome.org/PathwayBrowser/#/R-SSC-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA IEA Sus scrofa A0A286ZSG4 R-SSC-6791222 https://reactome.org/PathwayBrowser/#/R-SSC-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Sus scrofa A0A286ZSG4 R-SSC-6791227 https://reactome.org/PathwayBrowser/#/R-SSC-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Sus scrofa A0A286ZSG6 R-SSC-9696271 https://reactome.org/PathwayBrowser/#/R-SSC-9696271 RND1 binds effectors IEA Sus scrofa A0A286ZSI3 R-SSC-1251997 https://reactome.org/PathwayBrowser/#/R-SSC-1251997 Cleavage of ERBB4m80 by gamma-scretase complex IEA Sus scrofa A0A286ZSI3 R-SSC-193682 https://reactome.org/PathwayBrowser/#/R-SSC-193682 gamma-secretase cleaves the p75NTR transmembrane domain IEA Sus scrofa A0A286ZSI3 R-SSC-3928656 https://reactome.org/PathwayBrowser/#/R-SSC-3928656 gamma-secretase cleaves EPHB2 IEA Sus scrofa A0A286ZSI3 R-SSC-6798739 https://reactome.org/PathwayBrowser/#/R-SSC-6798739 Exocytosis of azurophil granule membrane proteins IEA Sus scrofa A0A286ZSI3 R-SSC-9839376 https://reactome.org/PathwayBrowser/#/R-SSC-9839376 TGFBR3(784-851) degradation IEA Sus scrofa A0A286ZSJ7 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A286ZSJ7 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A286ZSJ7 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A286ZSJ7 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A286ZSJ7 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A286ZSJ7 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A286ZSJ7 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A286ZSL1 R-SSC-76056 https://reactome.org/PathwayBrowser/#/R-SSC-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Sus scrofa A0A286ZSL1 R-SSC-83788 https://reactome.org/PathwayBrowser/#/R-SSC-83788 Binding of TFIIIC to Type 2 promoter IEA Sus scrofa A0A286ZSL1 R-SSC-83805 https://reactome.org/PathwayBrowser/#/R-SSC-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Sus scrofa A0A286ZSM1 R-SSC-5676637 https://reactome.org/PathwayBrowser/#/R-SSC-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Sus scrofa A0A286ZSM5 R-SSC-198983 https://reactome.org/PathwayBrowser/#/R-SSC-198983 NKG2D homodimer interacting with ligands IEA Sus scrofa A0A286ZSM5 R-SSC-210289 https://reactome.org/PathwayBrowser/#/R-SSC-210289 Recruitment of SYK to p-DAP12 IEA Sus scrofa A0A286ZSM5 R-SSC-2395412 https://reactome.org/PathwayBrowser/#/R-SSC-2395412 Phosphorylation of SYK IEA Sus scrofa A0A286ZSM5 R-SSC-2395801 https://reactome.org/PathwayBrowser/#/R-SSC-2395801 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A286ZSM5 R-SSC-2396594 https://reactome.org/PathwayBrowser/#/R-SSC-2396594 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A286ZSM5 R-SSC-2424480 https://reactome.org/PathwayBrowser/#/R-SSC-2424480 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZSM5 R-SSC-2424482 https://reactome.org/PathwayBrowser/#/R-SSC-2424482 p85 regulatory unit of PI3K binds p-6Y-SYK IEA Sus scrofa A0A286ZSM5 R-SSC-2424484 https://reactome.org/PathwayBrowser/#/R-SSC-2424484 Phosphorylation of BTK by p-SYK IEA Sus scrofa A0A286ZSM5 R-SSC-2424486 https://reactome.org/PathwayBrowser/#/R-SSC-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Sus scrofa A0A286ZSM5 R-SSC-2424487 https://reactome.org/PathwayBrowser/#/R-SSC-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Sus scrofa A0A286ZSM8 R-SSC-2045911 https://reactome.org/PathwayBrowser/#/R-SSC-2045911 BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 IEA Sus scrofa A0A286ZSM8 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZSN9 R-SSC-191763 https://reactome.org/PathwayBrowser/#/R-SSC-191763 snRNP:Snurportin complex formation IEA Sus scrofa A0A286ZSN9 R-SSC-191784 https://reactome.org/PathwayBrowser/#/R-SSC-191784 snRNA Cap hypermethylation IEA Sus scrofa A0A286ZSN9 R-SSC-191790 https://reactome.org/PathwayBrowser/#/R-SSC-191790 Loading and methylation of Sm proteins onto SMN Complexes IEA Sus scrofa A0A286ZSN9 R-SSC-191830 https://reactome.org/PathwayBrowser/#/R-SSC-191830 snRNP nuclear import and release IEA Sus scrofa A0A286ZSQ8 R-SSC-4085033 https://reactome.org/PathwayBrowser/#/R-SSC-4085033 ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) IEA Sus scrofa A0A286ZSQ8 R-SSC-975902 https://reactome.org/PathwayBrowser/#/R-SSC-975902 ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans IEA Sus scrofa A0A286ZSQ8 R-SSC-977071 https://reactome.org/PathwayBrowser/#/R-SSC-977071 ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens IEA Sus scrofa A0A286ZSR0 R-SSC-200651 https://reactome.org/PathwayBrowser/#/R-SSC-200651 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine IEA Sus scrofa A0A286ZSR0 R-SSC-200735 https://reactome.org/PathwayBrowser/#/R-SSC-200735 SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG IEA Sus scrofa A0A286ZSR0 R-SSC-71249 https://reactome.org/PathwayBrowser/#/R-SSC-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Sus scrofa A0A286ZSR2 R-SSC-6814555 https://reactome.org/PathwayBrowser/#/R-SSC-6814555 Integrator complex processes the 3' end of snRNA IEA Sus scrofa A0A286ZSR2 R-SSC-6814885 https://reactome.org/PathwayBrowser/#/R-SSC-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Sus scrofa A0A286ZST1 R-SSC-4827382 https://reactome.org/PathwayBrowser/#/R-SSC-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Sus scrofa A0A286ZST1 R-SSC-5159250 https://reactome.org/PathwayBrowser/#/R-SSC-5159250 ATF7IP binds SETDB1 IEA Sus scrofa A0A286ZST1 R-SSC-9842833 https://reactome.org/PathwayBrowser/#/R-SSC-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Sus scrofa A0A286ZST1 R-SSC-9844006 https://reactome.org/PathwayBrowser/#/R-SSC-9844006 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) IEA Sus scrofa A0A286ZST1 R-SSC-9844057 https://reactome.org/PathwayBrowser/#/R-SSC-9844057 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome IEA Sus scrofa A0A286ZST2 R-SSC-6791221 https://reactome.org/PathwayBrowser/#/R-SSC-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA IEA Sus scrofa A0A286ZST2 R-SSC-6791222 https://reactome.org/PathwayBrowser/#/R-SSC-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Sus scrofa A0A286ZST2 R-SSC-6791227 https://reactome.org/PathwayBrowser/#/R-SSC-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Sus scrofa A0A286ZST3 R-SSC-904864 https://reactome.org/PathwayBrowser/#/R-SSC-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Sus scrofa A0A286ZST8 R-SSC-8876191 https://reactome.org/PathwayBrowser/#/R-SSC-8876191 RAB9 GEFs exchange GTP for GDP on RAB9 IEA Sus scrofa A0A286ZSU9 R-SSC-6785126 https://reactome.org/PathwayBrowser/#/R-SSC-6785126 FA core complex assembles at DNA interstrand crosslinks (ICLs) IEA Sus scrofa A0A286ZSU9 R-SSC-6785342 https://reactome.org/PathwayBrowser/#/R-SSC-6785342 FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex IEA Sus scrofa A0A286ZSU9 R-SSC-6785361 https://reactome.org/PathwayBrowser/#/R-SSC-6785361 Monoubiquitination of FANCD2:FANCI IEA Sus scrofa A0A286ZSU9 R-SSC-6785732 https://reactome.org/PathwayBrowser/#/R-SSC-6785732 DNA nucleases bind monoubiquitinated ID2 complex IEA Sus scrofa A0A286ZSU9 R-SSC-6785986 https://reactome.org/PathwayBrowser/#/R-SSC-6785986 DNA nucleases unhook the interstrand crosslink (ICL) IEA Sus scrofa A0A286ZSU9 R-SSC-6786155 https://reactome.org/PathwayBrowser/#/R-SSC-6786155 POLN binds ICL-DNA IEA Sus scrofa A0A286ZSU9 R-SSC-6786166 https://reactome.org/PathwayBrowser/#/R-SSC-6786166 Translesion synthesis across unhooked ICL by POLN IEA Sus scrofa A0A286ZSU9 R-SSC-6786171 https://reactome.org/PathwayBrowser/#/R-SSC-6786171 FANCD2 deubiquitination by USP1:WDR48 IEA Sus scrofa A0A286ZSU9 R-SSC-6788385 https://reactome.org/PathwayBrowser/#/R-SSC-6788385 The complex of ATR and ATRIP is recruited to ICL-DNA IEA Sus scrofa A0A286ZSU9 R-SSC-6788392 https://reactome.org/PathwayBrowser/#/R-SSC-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Sus scrofa A0A286ZSU9 R-SSC-9835411 https://reactome.org/PathwayBrowser/#/R-SSC-9835411 FA core complex:HSP70s binds PKR IEA Sus scrofa A0A286ZSV4 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A286ZSW9 R-SSC-201712 https://reactome.org/PathwayBrowser/#/R-SSC-201712 Beta-catenin:TCF associates with BCL9 and PYGO IEA Sus scrofa A0A286ZSW9 R-SSC-3299569 https://reactome.org/PathwayBrowser/#/R-SSC-3299569 Beta-catenin displaces TLE:HDAC1 from TCF/LEF IEA Sus scrofa A0A286ZSW9 R-SSC-3322422 https://reactome.org/PathwayBrowser/#/R-SSC-3322422 Beta-catenin recruits SMARCA4 IEA Sus scrofa A0A286ZSW9 R-SSC-3322424 https://reactome.org/PathwayBrowser/#/R-SSC-3322424 Beta-catenin recruits CDC73 and LEO1 IEA Sus scrofa A0A286ZSW9 R-SSC-3322427 https://reactome.org/PathwayBrowser/#/R-SSC-3322427 Beta-catenin recruits CBP/p300 IEA Sus scrofa A0A286ZSW9 R-SSC-3361751 https://reactome.org/PathwayBrowser/#/R-SSC-3361751 beta-catenin is replaced by repression complexes at the promoter IEA Sus scrofa A0A286ZSW9 R-SSC-3451153 https://reactome.org/PathwayBrowser/#/R-SSC-3451153 Beta-catenin recruits TRRAP/KAT5 HAT components IEA Sus scrofa A0A286ZSW9 R-SSC-4411383 https://reactome.org/PathwayBrowser/#/R-SSC-4411383 NLK phosphorylates TCF/LEF IEA Sus scrofa A0A286ZSW9 R-SSC-5334050 https://reactome.org/PathwayBrowser/#/R-SSC-5334050 TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes IEA Sus scrofa A0A286ZSW9 R-SSC-5665608 https://reactome.org/PathwayBrowser/#/R-SSC-5665608 TCF:Beta-catenin binds SOX proteins IEA Sus scrofa A0A286ZSW9 R-SSC-8944349 https://reactome.org/PathwayBrowser/#/R-SSC-8944349 TLE tetramers bind TCF/LEF at WNT promoters IEA Sus scrofa A0A286ZSW9 R-SSC-8951428 https://reactome.org/PathwayBrowser/#/R-SSC-8951428 RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) IEA Sus scrofa A0A286ZSW9 R-SSC-9858647 https://reactome.org/PathwayBrowser/#/R-SSC-9858647 HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter IEA Sus scrofa A0A286ZSX6 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A286ZSX6 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A286ZSX6 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A286ZSX6 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A286ZSX6 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A286ZSX6 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A286ZSX6 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A286ZSX6 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A286ZSX6 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A286ZSX6 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZSX6 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A286ZSX6 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A286ZSX6 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A286ZSX6 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A286ZSX6 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A286ZSX6 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A286ZSX6 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A286ZSX6 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A286ZSX6 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A286ZSX6 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A286ZSX6 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A286ZSX6 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A286ZSX6 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A286ZSX6 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A286ZSX6 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A286ZSX6 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A286ZSX6 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A286ZSX6 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A286ZSX6 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A286ZSX6 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A286ZSX6 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A286ZSX6 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A286ZSX6 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A286ZSX6 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A286ZSX6 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A286ZSX6 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A286ZSX6 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A286ZSX6 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A286ZSX6 R-SSC-8858498 https://reactome.org/PathwayBrowser/#/R-SSC-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Sus scrofa A0A286ZSX6 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A286ZSX6 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A286ZSX6 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A286ZSX6 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A286ZSX6 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A286ZSX6 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A286ZSX6 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A286ZSX6 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A286ZSX6 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A286ZSZ9 R-SSC-3928578 https://reactome.org/PathwayBrowser/#/R-SSC-3928578 EPH receptors autophosphorylate IEA Sus scrofa A0A286ZSZ9 R-SSC-3928591 https://reactome.org/PathwayBrowser/#/R-SSC-3928591 EPH:EFN tetramers oligomerise IEA Sus scrofa A0A286ZSZ9 R-SSC-3928597 https://reactome.org/PathwayBrowser/#/R-SSC-3928597 EPH:EFN dimers tetramerise IEA Sus scrofa A0A286ZSZ9 R-SSC-3928604 https://reactome.org/PathwayBrowser/#/R-SSC-3928604 SFKs phosphorylate VAV2,3 IEA Sus scrofa A0A286ZSZ9 R-SSC-3928607 https://reactome.org/PathwayBrowser/#/R-SSC-3928607 p-EPHs bind VAV2,3 IEA Sus scrofa A0A286ZSZ9 R-SSC-3928628 https://reactome.org/PathwayBrowser/#/R-SSC-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa A0A286ZSZ9 R-SSC-3928642 https://reactome.org/PathwayBrowser/#/R-SSC-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa A0A286ZSZ9 R-SSC-3928646 https://reactome.org/PathwayBrowser/#/R-SSC-3928646 EPHAs bind EFNAs IEA Sus scrofa A0A286ZSZ9 R-SSC-3928651 https://reactome.org/PathwayBrowser/#/R-SSC-3928651 NGEF exchanges GTP for GDP on RHOA IEA Sus scrofa A0A286ZSZ9 R-SSC-4093327 https://reactome.org/PathwayBrowser/#/R-SSC-4093327 EPHA binds TIAM1 IEA Sus scrofa A0A286ZT06 R-SSC-111930 https://reactome.org/PathwayBrowser/#/R-SSC-111930 Adenylate cyclase produces cAMP IEA Sus scrofa A0A286ZT06 R-SSC-170666 https://reactome.org/PathwayBrowser/#/R-SSC-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Sus scrofa A0A286ZT06 R-SSC-170671 https://reactome.org/PathwayBrowser/#/R-SSC-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Sus scrofa A0A286ZT06 R-SSC-170672 https://reactome.org/PathwayBrowser/#/R-SSC-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Sus scrofa A0A286ZT06 R-SSC-170674 https://reactome.org/PathwayBrowser/#/R-SSC-170674 Dissociation of the Gi alpha:G olf complex IEA Sus scrofa A0A286ZT06 R-SSC-170676 https://reactome.org/PathwayBrowser/#/R-SSC-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Sus scrofa A0A286ZT06 R-SSC-170677 https://reactome.org/PathwayBrowser/#/R-SSC-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Sus scrofa A0A286ZT06 R-SSC-170685 https://reactome.org/PathwayBrowser/#/R-SSC-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Sus scrofa A0A286ZT06 R-SSC-170686 https://reactome.org/PathwayBrowser/#/R-SSC-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Sus scrofa A0A286ZT06 R-SSC-392064 https://reactome.org/PathwayBrowser/#/R-SSC-392064 G alpha (z) inhibits adenylate cyclase IEA Sus scrofa A0A286ZT06 R-SSC-5610727 https://reactome.org/PathwayBrowser/#/R-SSC-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Sus scrofa A0A286ZT28 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A286ZT30 R-SSC-392513 https://reactome.org/PathwayBrowser/#/R-SSC-392513 Rap1 signal termination by Rap1GAPs IEA Sus scrofa A0A286ZT30 R-SSC-913993 https://reactome.org/PathwayBrowser/#/R-SSC-913993 14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 IEA Sus scrofa A0A286ZT30 R-SSC-913996 https://reactome.org/PathwayBrowser/#/R-SSC-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Sus scrofa A0A286ZT62 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa A0A286ZT62 R-SSC-444838 https://reactome.org/PathwayBrowser/#/R-SSC-444838 Relaxin receptor 1 binds relaxin 2 and 3 IEA Sus scrofa A0A286ZTD8 R-SSC-169895 https://reactome.org/PathwayBrowser/#/R-SSC-169895 Crk's SH3 domain engages C3G IEA Sus scrofa A0A286ZTD8 R-SSC-169904 https://reactome.org/PathwayBrowser/#/R-SSC-169904 C3G stimulates nucleotide exchange on Rap1 IEA Sus scrofa A0A286ZTD8 R-SSC-169905 https://reactome.org/PathwayBrowser/#/R-SSC-169905 ARMS is phosphorylated by active TrkA receptor IEA Sus scrofa A0A286ZTD8 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A286ZTD8 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A286ZTD8 R-SSC-372697 https://reactome.org/PathwayBrowser/#/R-SSC-372697 Crk binding to p130cas IEA Sus scrofa A0A286ZTD8 R-SSC-382052 https://reactome.org/PathwayBrowser/#/R-SSC-382052 p130Cas and C3G bind PDGFR bound Crk IEA Sus scrofa A0A286ZTD8 R-SSC-382056 https://reactome.org/PathwayBrowser/#/R-SSC-382056 Crk binds to the active PDGF receptor IEA Sus scrofa A0A286ZTD8 R-SSC-5218811 https://reactome.org/PathwayBrowser/#/R-SSC-5218811 DOCK180:ELMO binds CRK IEA Sus scrofa A0A286ZTD8 R-SSC-5218822 https://reactome.org/PathwayBrowser/#/R-SSC-5218822 CRK binds BCAR1 and or PXN IEA Sus scrofa A0A286ZTD8 R-SSC-5218839 https://reactome.org/PathwayBrowser/#/R-SSC-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Sus scrofa A0A286ZTD8 R-SSC-8848611 https://reactome.org/PathwayBrowser/#/R-SSC-8848611 Phosphorylated PXN recruits the CRK complex IEA Sus scrofa A0A286ZTD8 R-SSC-8848618 https://reactome.org/PathwayBrowser/#/R-SSC-8848618 Activation of RAC1 by the PXN:CRK complex IEA Sus scrofa A0A286ZTD8 R-SSC-8875540 https://reactome.org/PathwayBrowser/#/R-SSC-8875540 GAB1 recruits CRK,CRKL to MET IEA Sus scrofa A0A286ZTD8 R-SSC-8875558 https://reactome.org/PathwayBrowser/#/R-SSC-8875558 RAPGEF1 binds CRK,CRKL IEA Sus scrofa A0A286ZTD8 R-SSC-8875568 https://reactome.org/PathwayBrowser/#/R-SSC-8875568 RAPGEF1 activates RAP1 IEA Sus scrofa A0A286ZTD8 R-SSC-8875576 https://reactome.org/PathwayBrowser/#/R-SSC-8875576 CRK,CRKL recruits RAC1 GEF to activated MET IEA Sus scrofa A0A286ZTD8 R-SSC-8875591 https://reactome.org/PathwayBrowser/#/R-SSC-8875591 DOCK7 activates RAC1 IEA Sus scrofa A0A286ZTD8 R-SSC-8875659 https://reactome.org/PathwayBrowser/#/R-SSC-8875659 RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane IEA Sus scrofa A0A286ZTD8 R-SSC-8875661 https://reactome.org/PathwayBrowser/#/R-SSC-8875661 GGA3 associates with activated MET receptor IEA Sus scrofa A0A286ZTD8 R-SSC-912734 https://reactome.org/PathwayBrowser/#/R-SSC-912734 CBL:CRKL binds RAPGEF1 IEA Sus scrofa A0A286ZTD8 R-SSC-912790 https://reactome.org/PathwayBrowser/#/R-SSC-912790 CBL binds CRK IEA Sus scrofa A0A286ZTE2 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A286ZTE2 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A286ZTE2 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A286ZTE2 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A286ZTE2 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A286ZTE2 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A286ZTE2 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A286ZTE2 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A286ZTE2 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A286ZTE2 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A286ZTE6 R-SSC-168166 https://reactome.org/PathwayBrowser/#/R-SSC-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Sus scrofa A0A286ZTE6 R-SSC-2467665 https://reactome.org/PathwayBrowser/#/R-SSC-2467665 AGRN binds Beta amyloid fibril via GAG chains IEA Sus scrofa A0A286ZTE6 R-SSC-481007 https://reactome.org/PathwayBrowser/#/R-SSC-481007 Exocytosis of platelet alpha granule contents IEA Sus scrofa A0A286ZTE6 R-SSC-5229111 https://reactome.org/PathwayBrowser/#/R-SSC-5229111 AP4 transports APP from trans-Golgi network to endosome lumen IEA Sus scrofa A0A286ZTE6 R-SSC-5229132 https://reactome.org/PathwayBrowser/#/R-SSC-5229132 AP4 binds APP IEA Sus scrofa A0A286ZTE6 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A286ZTE6 R-SSC-879411 https://reactome.org/PathwayBrowser/#/R-SSC-879411 Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor IEA Sus scrofa A0A286ZTE6 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A286ZTE6 R-SSC-9617595 https://reactome.org/PathwayBrowser/#/R-SSC-9617595 SGTA binds mislocalized membrane protein IEA Sus scrofa A0A286ZTE6 R-SSC-9839072 https://reactome.org/PathwayBrowser/#/R-SSC-9839072 HTRA2 degrades APP (Amyloid-beta precursor protein) IEA Sus scrofa A0A286ZTH5 R-SSC-481010 https://reactome.org/PathwayBrowser/#/R-SSC-481010 Surface deployment of platelet dense granule membrane components IEA Sus scrofa A0A286ZTH5 R-SSC-8877308 https://reactome.org/PathwayBrowser/#/R-SSC-8877308 MADD exchanges GTP for GDP on RAB27 IEA Sus scrofa A0A286ZTI5 R-SSC-199518 https://reactome.org/PathwayBrowser/#/R-SSC-199518 C3d-complexed antigen binds to complement receptor IEA Sus scrofa A0A286ZTI5 R-SSC-8853252 https://reactome.org/PathwayBrowser/#/R-SSC-8853252 CR2:C3d,C3dg,iC3b binds CD19:CD81 IEA Sus scrofa A0A286ZTI6 R-SSC-9913330 https://reactome.org/PathwayBrowser/#/R-SSC-9913330 SGCG,SGCZ and SGCA, SGCE bind SGCB:SGCD IEA Sus scrofa A0A286ZTI6 R-SSC-9913332 https://reactome.org/PathwayBrowser/#/R-SSC-9913332 DAG1(30-653), DAG1(654-895) and SSPN bind SGC IEA Sus scrofa A0A286ZTI6 R-SSC-9913333 https://reactome.org/PathwayBrowser/#/R-SSC-9913333 DGC complex binds laminins IEA Sus scrofa A0A286ZTI6 R-SSC-9913336 https://reactome.org/PathwayBrowser/#/R-SSC-9913336 SGC:DAG1:SSPN complex translocates to plasma membrane IEA Sus scrofa A0A286ZTI6 R-SSC-9913338 https://reactome.org/PathwayBrowser/#/R-SSC-9913338 Sarcoglycan complex (SGC) translocates to the Golgi membrane IEA Sus scrofa A0A286ZTI6 R-SSC-9913339 https://reactome.org/PathwayBrowser/#/R-SSC-9913339 Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC IEA Sus scrofa A0A286ZTI6 R-SSC-9914537 https://reactome.org/PathwayBrowser/#/R-SSC-9914537 DGC complex binds AGRN and HSPG2 IEA Sus scrofa A0A286ZTI9 R-SSC-1889955 https://reactome.org/PathwayBrowser/#/R-SSC-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Sus scrofa A0A286ZTK1 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A286ZTK1 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A286ZTK1 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A286ZTK1 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A286ZTK1 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A286ZTK1 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A286ZTK1 R-SSC-170072 https://reactome.org/PathwayBrowser/#/R-SSC-170072 Translocation of Cyclin B1:phospho-Cdc2 to the cytoplasm IEA Sus scrofa A0A286ZTK1 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A286ZTK1 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A286ZTK1 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A286ZTK1 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A286ZTK1 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A286ZTK1 R-SSC-3769392 https://reactome.org/PathwayBrowser/#/R-SSC-3769392 YWHAZ and XPO1 mediate the nuclear export of beta-catenin IEA Sus scrofa A0A286ZTK1 R-SSC-450387 https://reactome.org/PathwayBrowser/#/R-SSC-450387 HuR binds the CRM1 nuclear export machinery IEA Sus scrofa A0A286ZTK1 R-SSC-450595 https://reactome.org/PathwayBrowser/#/R-SSC-450595 HuR:mRNA complex translocates from the nucleus to the cytosol IEA Sus scrofa A0A286ZTK1 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A286ZTK1 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A286ZTK1 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A286ZTK1 R-SSC-5687109 https://reactome.org/PathwayBrowser/#/R-SSC-5687109 MAPK4,6 translocate to the cytoplasm IEA Sus scrofa A0A286ZTK1 R-SSC-9632873 https://reactome.org/PathwayBrowser/#/R-SSC-9632873 p-S10 CDKN1B translocates to the cytosol IEA Sus scrofa A0A286ZTK1 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A286ZTK1 R-SSC-9708423 https://reactome.org/PathwayBrowser/#/R-SSC-9708423 XPO1:BACH1:Hemes are transported out of the nucleus IEA Sus scrofa A0A286ZTK1 R-SSC-9708430 https://reactome.org/PathwayBrowser/#/R-SSC-9708430 XPO1 (CRM1) binds to BACH1:Hemes IEA Sus scrofa A0A286ZTK1 R-SSC-9824979 https://reactome.org/PathwayBrowser/#/R-SSC-9824979 XPO1 binds p-S69,73 MITF-M IEA Sus scrofa A0A286ZTK1 R-SSC-9824986 https://reactome.org/PathwayBrowser/#/R-SSC-9824986 XPO1-dependent export of p-S69,S73 MITF-M IEA Sus scrofa A0A286ZTK8 R-SSC-3228469 https://reactome.org/PathwayBrowser/#/R-SSC-3228469 MAP3K5 phosphorylates MKK3 and MKK6 IEA Sus scrofa A0A286ZTK8 R-SSC-3238999 https://reactome.org/PathwayBrowser/#/R-SSC-3238999 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 IEA Sus scrofa A0A286ZTK8 R-SSC-450296 https://reactome.org/PathwayBrowser/#/R-SSC-450296 Phosphorylated MKK3/MKK6 migrates to nucleus IEA Sus scrofa A0A286ZTK8 R-SSC-450333 https://reactome.org/PathwayBrowser/#/R-SSC-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 IEA Sus scrofa A0A286ZTK8 R-SSC-450346 https://reactome.org/PathwayBrowser/#/R-SSC-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Sus scrofa A0A286ZTM0 R-SSC-216069 https://reactome.org/PathwayBrowser/#/R-SSC-216069 Interaction of integrin alphaDbeta2 with fibrin IEA Sus scrofa A0A286ZTM3 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A286ZTM3 R-SSC-388503 https://reactome.org/PathwayBrowser/#/R-SSC-388503 Oxytocin receptor bind oxytocin IEA Sus scrofa A0A286ZTM3 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A286ZTM3 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A286ZTN2 R-SSC-9012721 https://reactome.org/PathwayBrowser/#/R-SSC-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Sus scrofa A0A286ZTN2 R-SSC-9013471 https://reactome.org/PathwayBrowser/#/R-SSC-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Sus scrofa A0A286ZTN2 R-SSC-9013533 https://reactome.org/PathwayBrowser/#/R-SSC-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Sus scrofa A0A286ZTN2 R-SSC-9034756 https://reactome.org/PathwayBrowser/#/R-SSC-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Sus scrofa A0A286ZTN2 R-SSC-9035484 https://reactome.org/PathwayBrowser/#/R-SSC-9035484 MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST IEA Sus scrofa A0A286ZTN4 R-SSC-9018758 https://reactome.org/PathwayBrowser/#/R-SSC-9018758 RHOH binds effectors at the plasma membrane IEA Sus scrofa A0A286ZTQ8 R-SSC-5620921 https://reactome.org/PathwayBrowser/#/R-SSC-5620921 ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex IEA Sus scrofa A0A286ZTQ8 R-SSC-5623513 https://reactome.org/PathwayBrowser/#/R-SSC-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Sus scrofa A0A286ZTQ8 R-SSC-5623519 https://reactome.org/PathwayBrowser/#/R-SSC-5623519 RAB3IP and RAB8A bind to the ciliary targeting complex IEA Sus scrofa A0A286ZTQ8 R-SSC-5623521 https://reactome.org/PathwayBrowser/#/R-SSC-5623521 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A286ZTQ8 R-SSC-5623524 https://reactome.org/PathwayBrowser/#/R-SSC-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Sus scrofa A0A286ZTQ8 R-SSC-5623525 https://reactome.org/PathwayBrowser/#/R-SSC-5623525 Cargo-carrying vesicles bud from the TGN IEA Sus scrofa A0A286ZTQ8 R-SSC-5623527 https://reactome.org/PathwayBrowser/#/R-SSC-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Sus scrofa A0A286ZTT0 R-SSC-114264 https://reactome.org/PathwayBrowser/#/R-SSC-114264 Translocation of activated BAX to the mitochondria IEA Sus scrofa A0A286ZTT0 R-SSC-114275 https://reactome.org/PathwayBrowser/#/R-SSC-114275 Oligomerization of BAX at the mitochondrial membrane IEA Sus scrofa A0A286ZTT0 R-SSC-114284 https://reactome.org/PathwayBrowser/#/R-SSC-114284 Release of Cytochrome c from mitochondria IEA Sus scrofa A0A286ZTT0 R-SSC-114307 https://reactome.org/PathwayBrowser/#/R-SSC-114307 Release of SMAC (DIABLO) from mitochondria IEA Sus scrofa A0A286ZTT0 R-SSC-139917 https://reactome.org/PathwayBrowser/#/R-SSC-139917 tBID activates BAX protein IEA Sus scrofa A0A286ZTT0 R-SSC-168849 https://reactome.org/PathwayBrowser/#/R-SSC-168849 tBID binds to inactive BAX protein IEA Sus scrofa A0A286ZTT0 R-SSC-6803892 https://reactome.org/PathwayBrowser/#/R-SSC-6803892 SFN dimer binds BAX IEA Sus scrofa A0A286ZTU8 R-SSC-449117 https://reactome.org/PathwayBrowser/#/R-SSC-449117 TXLNA (IL14) binds syntaxin1A IEA Sus scrofa A0A286ZTU8 R-SSC-9014052 https://reactome.org/PathwayBrowser/#/R-SSC-9014052 TXLNA (IL14) binds syntaxin3 IEA Sus scrofa A0A286ZTU8 R-SSC-9014074 https://reactome.org/PathwayBrowser/#/R-SSC-9014074 TXLNA (IL14) binds syntaxin4 IEA Sus scrofa A0A286ZTV6 R-SSC-1614336 https://reactome.org/PathwayBrowser/#/R-SSC-1614336 SUMF2 binds SUMF1, inhibiting SUMF1-mediated activation of arylsulfatases IEA Sus scrofa A0A286ZTV6 R-SSC-1614362 https://reactome.org/PathwayBrowser/#/R-SSC-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Sus scrofa A0A286ZTX3 R-SSC-3076905 https://reactome.org/PathwayBrowser/#/R-SSC-3076905 Extracellular BTD hydrolyses BCTN IEA Sus scrofa A0A286ZTX3 R-SSC-4167509 https://reactome.org/PathwayBrowser/#/R-SSC-4167509 Mitochondrial BTD hydrolyses BCTN IEA Sus scrofa A0A286ZTX5 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A286ZU07 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A286ZU07 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A286ZU07 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A286ZU07 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A286ZU07 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A286ZU07 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A286ZU07 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A286ZU07 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A286ZU07 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A286ZU07 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZU07 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A286ZU07 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A286ZU07 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A286ZU07 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A286ZU07 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A286ZU07 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A286ZU07 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A286ZU07 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A286ZU07 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A286ZU07 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A286ZU07 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A286ZU07 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A286ZU07 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A286ZU07 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A286ZU07 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A286ZU07 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A286ZU07 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A286ZU07 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A286ZU07 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A286ZU07 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A286ZU07 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A286ZU07 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A286ZU07 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A286ZU07 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A286ZU07 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A286ZU07 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A286ZU07 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A286ZU07 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A286ZU07 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A286ZU07 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A286ZU07 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A286ZU07 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A286ZU07 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A286ZU07 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A286ZU07 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A286ZU07 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A286ZU07 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A286ZU22 R-SSC-177479 https://reactome.org/PathwayBrowser/#/R-SSC-177479 Axonal transport of NGF:Trk complexes IEA Sus scrofa A0A286ZU22 R-SSC-190519 https://reactome.org/PathwayBrowser/#/R-SSC-190519 Internalization of gap junction plaques IEA Sus scrofa A0A286ZU22 R-SSC-190829 https://reactome.org/PathwayBrowser/#/R-SSC-190829 Lysosomal degradation of gap junction plaques IEA Sus scrofa A0A286ZU22 R-SSC-196017 https://reactome.org/PathwayBrowser/#/R-SSC-196017 Dynamin is recruited to the gap junction plaque IEA Sus scrofa A0A286ZU22 R-SSC-196026 https://reactome.org/PathwayBrowser/#/R-SSC-196026 Dab2 is recruited to the junctional plaques IEA Sus scrofa A0A286ZU22 R-SSC-2130486 https://reactome.org/PathwayBrowser/#/R-SSC-2130486 Uncoating of clathrin-coated vesicles and fusion with endosomes IEA Sus scrofa A0A286ZU22 R-SSC-2130640 https://reactome.org/PathwayBrowser/#/R-SSC-2130640 Recruitment of clathrin coated vesicle by Ii IEA Sus scrofa A0A286ZU22 R-SSC-2130725 https://reactome.org/PathwayBrowser/#/R-SSC-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Sus scrofa A0A286ZU22 R-SSC-392749 https://reactome.org/PathwayBrowser/#/R-SSC-392749 Transport of L1 into endosomes IEA Sus scrofa A0A286ZU22 R-SSC-416639 https://reactome.org/PathwayBrowser/#/R-SSC-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Sus scrofa A0A286ZU22 R-SSC-445079 https://reactome.org/PathwayBrowser/#/R-SSC-445079 Phosphorylation of L1 by ERK IEA Sus scrofa A0A286ZU22 R-SSC-5138433 https://reactome.org/PathwayBrowser/#/R-SSC-5138433 p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis IEA Sus scrofa A0A286ZU22 R-SSC-5138459 https://reactome.org/PathwayBrowser/#/R-SSC-5138459 WNT5A:FZD4 is endocytosed IEA Sus scrofa A0A286ZU22 R-SSC-5140747 https://reactome.org/PathwayBrowser/#/R-SSC-5140747 FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner IEA Sus scrofa A0A286ZU22 R-SSC-555065 https://reactome.org/PathwayBrowser/#/R-SSC-555065 Formation of clathrin coated vesicle IEA Sus scrofa A0A286ZU22 R-SSC-6784729 https://reactome.org/PathwayBrowser/#/R-SSC-6784729 PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome IEA Sus scrofa A0A286ZU22 R-SSC-6784735 https://reactome.org/PathwayBrowser/#/R-SSC-6784735 PCSK9:LDLR bind to Clathrin IEA Sus scrofa A0A286ZU22 R-SSC-6784738 https://reactome.org/PathwayBrowser/#/R-SSC-6784738 Degradation of PCSK9:LDLR:Clathrin-coated vesicle IEA Sus scrofa A0A286ZU22 R-SSC-8855130 https://reactome.org/PathwayBrowser/#/R-SSC-8855130 VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane IEA Sus scrofa A0A286ZU22 R-SSC-8855131 https://reactome.org/PathwayBrowser/#/R-SSC-8855131 VLDLR:PCSK9 binds Clathrin-coated vesicles IEA Sus scrofa A0A286ZU22 R-SSC-8856808 https://reactome.org/PathwayBrowser/#/R-SSC-8856808 Recruitment of AP-2 complex and clathrin IEA Sus scrofa A0A286ZU22 R-SSC-8856813 https://reactome.org/PathwayBrowser/#/R-SSC-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Sus scrofa A0A286ZU22 R-SSC-8866277 https://reactome.org/PathwayBrowser/#/R-SSC-8866277 AP-2 directly binds some endocytic cargo IEA Sus scrofa A0A286ZU22 R-SSC-8866279 https://reactome.org/PathwayBrowser/#/R-SSC-8866279 Epsin family proteins bind ubiquitinated cargo IEA Sus scrofa A0A286ZU22 R-SSC-8866283 https://reactome.org/PathwayBrowser/#/R-SSC-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Sus scrofa A0A286ZU22 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A286ZU22 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A286ZU22 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A286ZU22 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A286ZU22 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A286ZU22 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A286ZU22 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A286ZU22 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A286ZU22 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A286ZU22 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A286ZU22 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A286ZU22 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A286ZU22 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A286ZU22 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A286ZU22 R-SSC-8871196 https://reactome.org/PathwayBrowser/#/R-SSC-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Sus scrofa A0A286ZU22 R-SSC-9681616 https://reactome.org/PathwayBrowser/#/R-SSC-9681616 AP2 binds chlorpromazine IEA Sus scrofa A0A286ZU26 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A286ZU56 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A286ZU56 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A286ZU56 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A286ZU56 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A286ZU56 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A286ZU60 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A286ZU68 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A286ZU68 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A286ZU68 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A286ZU68 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A286ZU68 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A286ZU78 R-SSC-5362553 https://reactome.org/PathwayBrowser/#/R-SSC-5362553 NOTUM releases Hh-Np:GPC5 from the plasma membrane IEA Sus scrofa A0A286ZU78 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A286ZU93 R-SSC-419001 https://reactome.org/PathwayBrowser/#/R-SSC-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Sus scrofa A0A286ZU93 R-SSC-419002 https://reactome.org/PathwayBrowser/#/R-SSC-419002 Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin IEA Sus scrofa A0A286ZU96 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A286ZU96 R-SSC-389463 https://reactome.org/PathwayBrowser/#/R-SSC-389463 Proteinase-activated receptors can bind thrombin IEA Sus scrofa A0A286ZU96 R-SSC-418091 https://reactome.org/PathwayBrowser/#/R-SSC-418091 F2R binds ARRB1 IEA Sus scrofa A0A286ZU96 R-SSC-418158 https://reactome.org/PathwayBrowser/#/R-SSC-418158 SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) IEA Sus scrofa A0A286ZU96 R-SSC-418163 https://reactome.org/PathwayBrowser/#/R-SSC-418163 Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) IEA Sus scrofa A0A286ZU96 R-SSC-418170 https://reactome.org/PathwayBrowser/#/R-SSC-418170 F2R:ARRB1 binds MAPKs, SRC-1 IEA Sus scrofa A0A286ZU96 R-SSC-418172 https://reactome.org/PathwayBrowser/#/R-SSC-418172 F2R binds ARRB2 IEA Sus scrofa A0A286ZU96 R-SSC-418176 https://reactome.org/PathwayBrowser/#/R-SSC-418176 F2R:ARRB2 binds MAPKs, SRC-1 IEA Sus scrofa A0A286ZU96 R-SSC-418200 https://reactome.org/PathwayBrowser/#/R-SSC-418200 SRC-1 bound to ARRB2 is not activated IEA Sus scrofa A0A286ZU96 R-SSC-5607058 https://reactome.org/PathwayBrowser/#/R-SSC-5607058 Activated protein C:PROCR binds F2R IEA Sus scrofa A0A286ZU96 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A286ZU96 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A286ZU96 R-SSC-9708859 https://reactome.org/PathwayBrowser/#/R-SSC-9708859 Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it IEA Sus scrofa A0A286ZU96 R-SSC-9708866 https://reactome.org/PathwayBrowser/#/R-SSC-9708866 pro-F2R binds vorapaxar IEA Sus scrofa A0A286ZUB0 R-SSC-1482543 https://reactome.org/PathwayBrowser/#/R-SSC-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Sus scrofa A0A286ZUB0 R-SSC-426043 https://reactome.org/PathwayBrowser/#/R-SSC-426043 2-AG hydrolysis to arachidonate by MAGL IEA Sus scrofa A0A286ZUC3 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A286ZUC3 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A286ZUC3 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A286ZUC3 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZUC3 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A286ZUC3 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZUC3 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A286ZUD5 R-SSC-421831 https://reactome.org/PathwayBrowser/#/R-SSC-421831 trans-Golgi Network Coat Assembly IEA Sus scrofa A0A286ZUD5 R-SSC-421835 https://reactome.org/PathwayBrowser/#/R-SSC-421835 trans-Golgi Network Vesicle Scission IEA Sus scrofa A0A286ZUD6 R-SSC-111925 https://reactome.org/PathwayBrowser/#/R-SSC-111925 cAMP induces dissociation of inactive PKA tetramers IEA Sus scrofa A0A286ZUD6 R-SSC-177275 https://reactome.org/PathwayBrowser/#/R-SSC-177275 PKA phosphorylates DARPP-32 on Thr34 IEA Sus scrofa A0A286ZUD6 R-SSC-177284 https://reactome.org/PathwayBrowser/#/R-SSC-177284 PKA phosphorylates PDE4B IEA Sus scrofa A0A286ZUD6 R-SSC-180073 https://reactome.org/PathwayBrowser/#/R-SSC-180073 DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function IEA Sus scrofa A0A286ZUD6 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A286ZUD6 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A286ZUD6 R-SSC-265682 https://reactome.org/PathwayBrowser/#/R-SSC-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Sus scrofa A0A286ZUD6 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A286ZUD6 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A286ZUD6 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A286ZUD6 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A286ZUD6 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A286ZUD6 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A286ZUD6 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A286ZUD6 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A286ZUD6 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A286ZUD6 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A286ZUD6 R-SSC-381644 https://reactome.org/PathwayBrowser/#/R-SSC-381644 ER calcium channels open in response to activated PKA IEA Sus scrofa A0A286ZUD6 R-SSC-381713 https://reactome.org/PathwayBrowser/#/R-SSC-381713 Potassium voltage-gated channels close in reponse to PKA IEA Sus scrofa A0A286ZUD6 R-SSC-432232 https://reactome.org/PathwayBrowser/#/R-SSC-432232 Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) IEA Sus scrofa A0A286ZUD6 R-SSC-5218854 https://reactome.org/PathwayBrowser/#/R-SSC-5218854 p-Y420-FYN is phosphorylated on S21 IEA Sus scrofa A0A286ZUD6 R-SSC-5610720 https://reactome.org/PathwayBrowser/#/R-SSC-5610720 PKA phosphorylates GLI3 IEA Sus scrofa A0A286ZUD6 R-SSC-5610749 https://reactome.org/PathwayBrowser/#/R-SSC-5610749 cAMP dissociates PKA, promoting GLI processing IEA Sus scrofa A0A286ZUD6 R-SSC-5617179 https://reactome.org/PathwayBrowser/#/R-SSC-5617179 PRKACA phosphorylates TNNI3 IEA Sus scrofa A0A286ZUD6 R-SSC-5617182 https://reactome.org/PathwayBrowser/#/R-SSC-5617182 PRKACA phosphorylates PLN IEA Sus scrofa A0A286ZUD6 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A286ZUD6 R-SSC-5624473 https://reactome.org/PathwayBrowser/#/R-SSC-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit IEA Sus scrofa A0A286ZUD6 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A286ZUD6 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A286ZUD6 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A286ZUD6 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A286ZUD6 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A286ZUD6 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A286ZUD6 R-SSC-5682101 https://reactome.org/PathwayBrowser/#/R-SSC-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer IEA Sus scrofa A0A286ZUD6 R-SSC-5687088 https://reactome.org/PathwayBrowser/#/R-SSC-5687088 PKA phosphorylates MAPKAPK5 IEA Sus scrofa A0A286ZUD6 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A286ZUD6 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A286ZUD6 R-SSC-8854908 https://reactome.org/PathwayBrowser/#/R-SSC-8854908 PKA phosphorylates RET:GDNF:GFRA dimer IEA Sus scrofa A0A286ZUD6 R-SSC-8951727 https://reactome.org/PathwayBrowser/#/R-SSC-8951727 cAMP binds PKA tetramer IEA Sus scrofa A0A286ZUD6 R-SSC-913451 https://reactome.org/PathwayBrowser/#/R-SSC-913451 IL3RB is phosphorylated on Ser-585 IEA Sus scrofa A0A286ZUD6 R-SSC-913996 https://reactome.org/PathwayBrowser/#/R-SSC-913996 PKA/PKG phosphorylate Rap1GAP2 IEA Sus scrofa A0A286ZUD6 R-SSC-9838321 https://reactome.org/PathwayBrowser/#/R-SSC-9838321 PRKACA phosphorylates TFAM in the mitochondrial matrix IEA Sus scrofa A0A286ZUD6 R-SSC-9861318 https://reactome.org/PathwayBrowser/#/R-SSC-9861318 PKA phosphorylates NOS3 (eNOS) on serine-633 IEA Sus scrofa A0A286ZUD6 R-SSC-992708 https://reactome.org/PathwayBrowser/#/R-SSC-992708 Dual-specific AKAPs bind type I and II PKA regulatory subunits IEA Sus scrofa A0A286ZUE0 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa A0A286ZUE0 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa A0A286ZUE0 R-SSC-8980691 https://reactome.org/PathwayBrowser/#/R-SSC-8980691 RHOA GEFs activate RHOA IEA Sus scrofa A0A286ZUE0 R-SSC-9013023 https://reactome.org/PathwayBrowser/#/R-SSC-9013023 RHOB GEFs activate RHOB IEA Sus scrofa A0A286ZUE0 R-SSC-9013109 https://reactome.org/PathwayBrowser/#/R-SSC-9013109 RHOC GEFs activate RHOC IEA Sus scrofa A0A286ZUE0 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A286ZUE0 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa A0A286ZUE0 R-SSC-9014296 https://reactome.org/PathwayBrowser/#/R-SSC-9014296 RAC2 GEFs activate RAC2 IEA Sus scrofa A0A286ZUE0 R-SSC-9014433 https://reactome.org/PathwayBrowser/#/R-SSC-9014433 RHOG GEFs activate RHOG IEA Sus scrofa A0A286ZUE0 R-SSC-9017491 https://reactome.org/PathwayBrowser/#/R-SSC-9017491 RHOJ GEFs activate RHOJ IEA Sus scrofa A0A286ZUE0 R-SSC-9018747 https://reactome.org/PathwayBrowser/#/R-SSC-9018747 RHOQ GEFs activate RHOQ IEA Sus scrofa A0A286ZUE0 R-SSC-9018804 https://reactome.org/PathwayBrowser/#/R-SSC-9018804 RAC3 GEFs activate RAC3 IEA Sus scrofa A0A286ZUG4 R-SSC-2106614 https://reactome.org/PathwayBrowser/#/R-SSC-2106614 Duplex miRNA is loaded into Argonaute IEA Sus scrofa A0A286ZUG4 R-SSC-2106615 https://reactome.org/PathwayBrowser/#/R-SSC-2106615 Removal of siRNA passenger strand IEA Sus scrofa A0A286ZUG4 R-SSC-2106625 https://reactome.org/PathwayBrowser/#/R-SSC-2106625 Duplex siRNA is loaded into Argonaute IEA Sus scrofa A0A286ZUG4 R-SSC-210805 https://reactome.org/PathwayBrowser/#/R-SSC-210805 Removal of miRNA passenger strand IEA Sus scrofa A0A286ZUG4 R-SSC-426464 https://reactome.org/PathwayBrowser/#/R-SSC-426464 Dicer cleaves double-stranded RNA to yield double-stranded siRNA IEA Sus scrofa A0A286ZUH0 R-SSC-445699 https://reactome.org/PathwayBrowser/#/R-SSC-445699 ATP Hydrolysis By Myosin IEA Sus scrofa A0A286ZUH0 R-SSC-445700 https://reactome.org/PathwayBrowser/#/R-SSC-445700 Myosin Binds ATP IEA Sus scrofa A0A286ZUH0 R-SSC-445704 https://reactome.org/PathwayBrowser/#/R-SSC-445704 Calcium Binds Caldesmon IEA Sus scrofa A0A286ZUH0 R-SSC-445705 https://reactome.org/PathwayBrowser/#/R-SSC-445705 Release Of ADP From Myosin IEA Sus scrofa A0A286ZUI3 R-SSC-156913 https://reactome.org/PathwayBrowser/#/R-SSC-156913 Regeneration of eEF1A:GTP by eEF1B activity IEA Sus scrofa A0A286ZUI3 R-SSC-3371591 https://reactome.org/PathwayBrowser/#/R-SSC-3371591 Trimerization of cytosolic HSF1 IEA Sus scrofa A0A286ZUI3 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A286ZUI3 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A286ZUI3 R-SSC-8931974 https://reactome.org/PathwayBrowser/#/R-SSC-8931974 N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A IEA Sus scrofa A0A286ZUI3 R-SSC-8932413 https://reactome.org/PathwayBrowser/#/R-SSC-8932413 METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 IEA Sus scrofa A0A286ZUI9 R-SSC-3322001 https://reactome.org/PathwayBrowser/#/R-SSC-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Sus scrofa A0A286ZUI9 R-SSC-3322003 https://reactome.org/PathwayBrowser/#/R-SSC-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Sus scrofa A0A286ZUI9 R-SSC-3322005 https://reactome.org/PathwayBrowser/#/R-SSC-3322005 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a IEA Sus scrofa A0A286ZUI9 R-SSC-3322025 https://reactome.org/PathwayBrowser/#/R-SSC-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Sus scrofa A0A286ZUI9 R-SSC-3322041 https://reactome.org/PathwayBrowser/#/R-SSC-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Sus scrofa A0A286ZUI9 R-SSC-3322057 https://reactome.org/PathwayBrowser/#/R-SSC-3322057 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b IEA Sus scrofa A0A286ZUI9 R-SSC-3781018 https://reactome.org/PathwayBrowser/#/R-SSC-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Sus scrofa A0A286ZUI9 R-SSC-3781023 https://reactome.org/PathwayBrowser/#/R-SSC-3781023 PPP1R3C binds to glycogen:GYG1:GYS1 IEA Sus scrofa A0A286ZUI9 R-SSC-3781024 https://reactome.org/PathwayBrowser/#/R-SSC-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Sus scrofa A0A286ZUI9 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A286ZUI9 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A286ZUI9 R-SSC-71552 https://reactome.org/PathwayBrowser/#/R-SSC-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin IEA Sus scrofa A0A286ZUI9 R-SSC-71593 https://reactome.org/PathwayBrowser/#/R-SSC-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Sus scrofa A0A286ZUI9 R-SSC-9036727 https://reactome.org/PathwayBrowser/#/R-SSC-9036727 GAA hydrolyzes lysosomal glycogen IEA Sus scrofa A0A286ZUJ8 R-SSC-6810392 https://reactome.org/PathwayBrowser/#/R-SSC-6810392 TMEM55B translocates to the nucleus IEA Sus scrofa A0A286ZUJ8 R-SSC-6810410 https://reactome.org/PathwayBrowser/#/R-SSC-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Sus scrofa A0A286ZUJ9 R-SSC-202165 https://reactome.org/PathwayBrowser/#/R-SSC-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Sus scrofa A0A286ZUJ9 R-SSC-202168 https://reactome.org/PathwayBrowser/#/R-SSC-202168 Phosphorylation of ZAP-70 by Lck IEA Sus scrofa A0A286ZUJ9 R-SSC-202174 https://reactome.org/PathwayBrowser/#/R-SSC-202174 Activation of ZAP-70 IEA Sus scrofa A0A286ZUJ9 R-SSC-202214 https://reactome.org/PathwayBrowser/#/R-SSC-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Sus scrofa A0A286ZUJ9 R-SSC-202216 https://reactome.org/PathwayBrowser/#/R-SSC-202216 Phosphorylation of SLP-76 IEA Sus scrofa A0A286ZUJ9 R-SSC-202233 https://reactome.org/PathwayBrowser/#/R-SSC-202233 Inactivation of Lck by Csk IEA Sus scrofa A0A286ZUJ9 R-SSC-202245 https://reactome.org/PathwayBrowser/#/R-SSC-202245 Phosphorylation of TBSMs in LAT IEA Sus scrofa A0A286ZUJ9 R-SSC-202248 https://reactome.org/PathwayBrowser/#/R-SSC-202248 Phosphorylation of PLC-gamma1 IEA Sus scrofa A0A286ZUJ9 R-SSC-202291 https://reactome.org/PathwayBrowser/#/R-SSC-202291 Activation of Lck IEA Sus scrofa A0A286ZUJ9 R-SSC-202307 https://reactome.org/PathwayBrowser/#/R-SSC-202307 Change of PKC theta conformation IEA Sus scrofa A0A286ZUJ9 R-SSC-2130336 https://reactome.org/PathwayBrowser/#/R-SSC-2130336 Initial proteolyis of Ii by aspartic proteases to lip22 IEA Sus scrofa A0A286ZUJ9 R-SSC-2130349 https://reactome.org/PathwayBrowser/#/R-SSC-2130349 Generation of CLIP from lip10 IEA Sus scrofa A0A286ZUJ9 R-SSC-2130378 https://reactome.org/PathwayBrowser/#/R-SSC-2130378 Transport of MHC II:Ii complex to plasma membrane IEA Sus scrofa A0A286ZUJ9 R-SSC-2130393 https://reactome.org/PathwayBrowser/#/R-SSC-2130393 Transport of MHC II:Ii complex along Golgi to TGN IEA Sus scrofa A0A286ZUJ9 R-SSC-2130478 https://reactome.org/PathwayBrowser/#/R-SSC-2130478 Interaction of invariant chain trimer and MHC II alpha beta dimer IEA Sus scrofa A0A286ZUJ9 R-SSC-2130486 https://reactome.org/PathwayBrowser/#/R-SSC-2130486 Uncoating of clathrin-coated vesicles and fusion with endosomes IEA Sus scrofa A0A286ZUJ9 R-SSC-2130500 https://reactome.org/PathwayBrowser/#/R-SSC-2130500 Insertion of MHC II:Ii complex in to the plasma membrane IEA Sus scrofa A0A286ZUJ9 R-SSC-2130504 https://reactome.org/PathwayBrowser/#/R-SSC-2130504 Cleavage of lip22 to lip10 IEA Sus scrofa A0A286ZUJ9 R-SSC-2130619 https://reactome.org/PathwayBrowser/#/R-SSC-2130619 TGN-lysosomal vesicle coat assembly IEA Sus scrofa A0A286ZUJ9 R-SSC-2130640 https://reactome.org/PathwayBrowser/#/R-SSC-2130640 Recruitment of clathrin coated vesicle by Ii IEA Sus scrofa A0A286ZUJ9 R-SSC-2130641 https://reactome.org/PathwayBrowser/#/R-SSC-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Sus scrofa A0A286ZUJ9 R-SSC-2130725 https://reactome.org/PathwayBrowser/#/R-SSC-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Sus scrofa A0A286ZUJ9 R-SSC-2130731 https://reactome.org/PathwayBrowser/#/R-SSC-2130731 Formation of COPII vesicle IEA Sus scrofa A0A286ZUJ9 R-SSC-2213235 https://reactome.org/PathwayBrowser/#/R-SSC-2213235 Trafficking of nonameric complex in the endocytic pathway IEA Sus scrofa A0A286ZUJ9 R-SSC-2213236 https://reactome.org/PathwayBrowser/#/R-SSC-2213236 TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome IEA Sus scrofa A0A286ZUJ9 R-SSC-2213239 https://reactome.org/PathwayBrowser/#/R-SSC-2213239 Formation of MHC II alpha beta heterodimer IEA Sus scrofa A0A286ZUJ9 R-SSC-2213241 https://reactome.org/PathwayBrowser/#/R-SSC-2213241 Formation of nonameric complex IEA Sus scrofa A0A286ZUJ9 R-SSC-2213243 https://reactome.org/PathwayBrowser/#/R-SSC-2213243 Fusion of COPII vesicle with Golgi complex IEA Sus scrofa A0A286ZUJ9 R-SSC-2213244 https://reactome.org/PathwayBrowser/#/R-SSC-2213244 Loading of antigenic peptides IEA Sus scrofa A0A286ZUJ9 R-SSC-2213246 https://reactome.org/PathwayBrowser/#/R-SSC-2213246 Disassociation of CLIP from MHC II IEA Sus scrofa A0A286ZUJ9 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A286ZUJ9 R-SSC-389758 https://reactome.org/PathwayBrowser/#/R-SSC-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Sus scrofa A0A286ZUJ9 R-SSC-8852200 https://reactome.org/PathwayBrowser/#/R-SSC-8852200 Inactivation of LCK by PTPN22 IEA Sus scrofa A0A286ZUJ9 R-SSC-8855381 https://reactome.org/PathwayBrowser/#/R-SSC-8855381 PTPN22 dephosphorylates ZAP70 IEA Sus scrofa A0A286ZUJ9 R-SSC-8856157 https://reactome.org/PathwayBrowser/#/R-SSC-8856157 LAG3 (CD233) binds MHC II IEA Sus scrofa A0A286ZUJ9 R-SSC-8951498 https://reactome.org/PathwayBrowser/#/R-SSC-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Sus scrofa A0A286ZUJ9 R-SSC-8951500 https://reactome.org/PathwayBrowser/#/R-SSC-8951500 Dissociation of CANX from nonameric complex IEA Sus scrofa A0A286ZUL1 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZUL1 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A286ZUL1 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZUL1 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A286ZUL8 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A286ZUL8 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A286ZUL8 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A286ZUL8 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A286ZUL8 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A286ZUL8 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A286ZUL8 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A286ZUL8 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A286ZUL8 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A286ZUL8 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A286ZUL8 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A286ZUL8 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A286ZUL8 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A286ZUL8 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A286ZUL8 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A286ZUL8 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A286ZUL8 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A286ZUL8 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A286ZUL8 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A286ZUL8 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A286ZUL8 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A286ZUL8 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A286ZUL8 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A286ZUL8 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A286ZUL8 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A286ZUL8 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A286ZUL8 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A286ZUL8 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A286ZUL8 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A286ZUL8 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A286ZUL8 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A286ZUL8 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A286ZUL8 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A286ZUL8 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A286ZUL8 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A286ZUL8 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A286ZUL8 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A286ZUL8 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A286ZUL8 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A286ZUL8 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A286ZUL8 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A286ZUL8 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A286ZUL8 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A286ZUL8 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A286ZUL8 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A286ZUL8 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A286ZUL8 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A286ZUM2 R-SSC-416320 https://reactome.org/PathwayBrowser/#/R-SSC-416320 Trafficking of GluR1-containing AMPA receptors IEA Sus scrofa A0A286ZUM2 R-SSC-432164 https://reactome.org/PathwayBrowser/#/R-SSC-432164 Ca2+ influx into the post-synaptic cell IEA Sus scrofa A0A286ZUM2 R-SSC-438037 https://reactome.org/PathwayBrowser/#/R-SSC-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Sus scrofa A0A286ZUM2 R-SSC-451283 https://reactome.org/PathwayBrowser/#/R-SSC-451283 kainate receptor binds glutamate IEA Sus scrofa A0A286ZUM2 R-SSC-451311 https://reactome.org/PathwayBrowser/#/R-SSC-451311 Activation of Ca-permeable Kainate receptors IEA Sus scrofa A0A286ZUM2 R-SSC-5671993 https://reactome.org/PathwayBrowser/#/R-SSC-5671993 CIT-3 binds DLG4 IEA Sus scrofa A0A286ZUM2 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A286ZUM2 R-SSC-5682794 https://reactome.org/PathwayBrowser/#/R-SSC-5682794 LGI1 binds ADAM22 and ADAM23 IEA Sus scrofa A0A286ZUM2 R-SSC-6797554 https://reactome.org/PathwayBrowser/#/R-SSC-6797554 ABP1 binds SHANK proteins IEA Sus scrofa A0A286ZUM2 R-SSC-8849878 https://reactome.org/PathwayBrowser/#/R-SSC-8849878 PSD-95 binds NMDA receptor IEA Sus scrofa A0A286ZUM2 R-SSC-8849891 https://reactome.org/PathwayBrowser/#/R-SSC-8849891 SALMs 1-3 bind to PSD-95 family members IEA Sus scrofa A0A286ZUM2 R-SSC-8849906 https://reactome.org/PathwayBrowser/#/R-SSC-8849906 SALM1 binds NMDA receptor IEA Sus scrofa A0A286ZUN9 R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Sus scrofa A0A286ZUN9 R-SSC-6788523 https://reactome.org/PathwayBrowser/#/R-SSC-6788523 NUBPL transfers 4Fe-4S to Complex I subunits IEA Sus scrofa A0A286ZUN9 R-SSC-6799179 https://reactome.org/PathwayBrowser/#/R-SSC-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Sus scrofa A0A286ZUN9 R-SSC-6799191 https://reactome.org/PathwayBrowser/#/R-SSC-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Sus scrofa A0A286ZUN9 R-SSC-6799196 https://reactome.org/PathwayBrowser/#/R-SSC-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Sus scrofa A0A286ZUN9 R-SSC-6799202 https://reactome.org/PathwayBrowser/#/R-SSC-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Sus scrofa A0A286ZUN9 R-SSC-6799203 https://reactome.org/PathwayBrowser/#/R-SSC-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Sus scrofa A0A286ZUN9 R-SSC-6800868 https://reactome.org/PathwayBrowser/#/R-SSC-6800868 NDUF subunits bind to form the IP subcomplex IEA Sus scrofa A0A286ZUP2 R-SSC-418582 https://reactome.org/PathwayBrowser/#/R-SSC-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Sus scrofa A0A286ZUP2 R-SSC-8982012 https://reactome.org/PathwayBrowser/#/R-SSC-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Sus scrofa A0A286ZUP2 R-SSC-8982017 https://reactome.org/PathwayBrowser/#/R-SSC-8982017 Active G alpha (q) binds RGS proteins IEA Sus scrofa A0A286ZUP2 R-SSC-8982019 https://reactome.org/PathwayBrowser/#/R-SSC-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Sus scrofa A0A286ZUP2 R-SSC-8982020 https://reactome.org/PathwayBrowser/#/R-SSC-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Sus scrofa A0A286ZUP2 R-SSC-8982025 https://reactome.org/PathwayBrowser/#/R-SSC-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Sus scrofa A0A286ZUP2 R-SSC-8982026 https://reactome.org/PathwayBrowser/#/R-SSC-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Sus scrofa A0A286ZUQ0 R-SSC-109813 https://reactome.org/PathwayBrowser/#/R-SSC-109813 GRB2-1 binds SOS1 IEA Sus scrofa A0A286ZUQ0 R-SSC-109822 https://reactome.org/PathwayBrowser/#/R-SSC-109822 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 IEA Sus scrofa A0A286ZUQ0 R-SSC-109823 https://reactome.org/PathwayBrowser/#/R-SSC-109823 MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 IEA Sus scrofa A0A286ZUQ0 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A286ZUQ0 R-SSC-1250380 https://reactome.org/PathwayBrowser/#/R-SSC-1250380 Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers IEA Sus scrofa A0A286ZUQ0 R-SSC-1250383 https://reactome.org/PathwayBrowser/#/R-SSC-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Sus scrofa A0A286ZUQ0 R-SSC-1306969 https://reactome.org/PathwayBrowser/#/R-SSC-1306969 GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers IEA Sus scrofa A0A286ZUQ0 R-SSC-1306972 https://reactome.org/PathwayBrowser/#/R-SSC-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Sus scrofa A0A286ZUQ0 R-SSC-1433471 https://reactome.org/PathwayBrowser/#/R-SSC-1433471 Activation of RAS by p-KIT bound SOS1 IEA Sus scrofa A0A286ZUQ0 R-SSC-177936 https://reactome.org/PathwayBrowser/#/R-SSC-177936 GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR IEA Sus scrofa A0A286ZUQ0 R-SSC-177938 https://reactome.org/PathwayBrowser/#/R-SSC-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Sus scrofa A0A286ZUQ0 R-SSC-177943 https://reactome.org/PathwayBrowser/#/R-SSC-177943 GRB2:SOS1 complex binds to EGF:EGFR complex IEA Sus scrofa A0A286ZUQ0 R-SSC-177945 https://reactome.org/PathwayBrowser/#/R-SSC-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Sus scrofa A0A286ZUQ0 R-SSC-186826 https://reactome.org/PathwayBrowser/#/R-SSC-186826 GRB2:SOS1 complex binds to the active receptor IEA Sus scrofa A0A286ZUQ0 R-SSC-186834 https://reactome.org/PathwayBrowser/#/R-SSC-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Sus scrofa A0A286ZUQ0 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa A0A286ZUQ0 R-SSC-205244 https://reactome.org/PathwayBrowser/#/R-SSC-205244 Recruitment of CBL to KIT IEA Sus scrofa A0A286ZUQ0 R-SSC-205286 https://reactome.org/PathwayBrowser/#/R-SSC-205286 GRB2:SOS interacts with p-KIT IEA Sus scrofa A0A286ZUQ0 R-SSC-210974 https://reactome.org/PathwayBrowser/#/R-SSC-210974 Interaction of SOS-1 to Tie2 bound Grb2 IEA Sus scrofa A0A286ZUQ0 R-SSC-210977 https://reactome.org/PathwayBrowser/#/R-SSC-210977 Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) IEA Sus scrofa A0A286ZUQ0 R-SSC-2179407 https://reactome.org/PathwayBrowser/#/R-SSC-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) IEA Sus scrofa A0A286ZUQ0 R-SSC-2179415 https://reactome.org/PathwayBrowser/#/R-SSC-2179415 GRB2:SOS1 binds to HBEGF:p-Y-EGFR IEA Sus scrofa A0A286ZUQ0 R-SSC-2396561 https://reactome.org/PathwayBrowser/#/R-SSC-2396561 Recruitment of GADS:SLP-76 to p-5Y-LAT IEA Sus scrofa A0A286ZUQ0 R-SSC-2396594 https://reactome.org/PathwayBrowser/#/R-SSC-2396594 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A286ZUQ0 R-SSC-2396599 https://reactome.org/PathwayBrowser/#/R-SSC-2396599 Recruitment of GRB2:SOS to p-5Y-LAT IEA Sus scrofa A0A286ZUQ0 R-SSC-2396606 https://reactome.org/PathwayBrowser/#/R-SSC-2396606 Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT IEA Sus scrofa A0A286ZUQ0 R-SSC-2424476 https://reactome.org/PathwayBrowser/#/R-SSC-2424476 Activation of RAC1 by VAV2/3 IEA Sus scrofa A0A286ZUQ0 R-SSC-2424477 https://reactome.org/PathwayBrowser/#/R-SSC-2424477 SOS mediated nucleotide exchange of RAS (SHC) IEA Sus scrofa A0A286ZUQ0 R-SSC-2424481 https://reactome.org/PathwayBrowser/#/R-SSC-2424481 Recruitment of VAV and BTK to p-SLP-76 IEA Sus scrofa A0A286ZUQ0 R-SSC-2424484 https://reactome.org/PathwayBrowser/#/R-SSC-2424484 Phosphorylation of BTK by p-SYK IEA Sus scrofa A0A286ZUQ0 R-SSC-2424485 https://reactome.org/PathwayBrowser/#/R-SSC-2424485 Release of p-PLCG1 IEA Sus scrofa A0A286ZUQ0 R-SSC-2424486 https://reactome.org/PathwayBrowser/#/R-SSC-2424486 Phosphorylation and activation of VAV2/VAV3 by SYK IEA Sus scrofa A0A286ZUQ0 R-SSC-2424487 https://reactome.org/PathwayBrowser/#/R-SSC-2424487 Phosphorylation of PLC-gamma by p-BTK/p-SYK IEA Sus scrofa A0A286ZUQ0 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A286ZUQ0 R-SSC-2730837 https://reactome.org/PathwayBrowser/#/R-SSC-2730837 Recruitment of GRB2:SOS to p-10Y-NTAL IEA Sus scrofa A0A286ZUQ0 R-SSC-2730840 https://reactome.org/PathwayBrowser/#/R-SSC-2730840 Activation of RAC1 by VAV IEA Sus scrofa A0A286ZUQ0 R-SSC-2730841 https://reactome.org/PathwayBrowser/#/R-SSC-2730841 Phosphorylation and activation of VAV IEA Sus scrofa A0A286ZUQ0 R-SSC-2730842 https://reactome.org/PathwayBrowser/#/R-SSC-2730842 PI3K associates with phosphorylated GAB2 IEA Sus scrofa A0A286ZUQ0 R-SSC-2730844 https://reactome.org/PathwayBrowser/#/R-SSC-2730844 Interaction of GRB2:SOS complex with p-SHC1 IEA Sus scrofa A0A286ZUQ0 R-SSC-2730847 https://reactome.org/PathwayBrowser/#/R-SSC-2730847 Hydrolysis of PIP2 by PLCG IEA Sus scrofa A0A286ZUQ0 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A286ZUQ0 R-SSC-2730856 https://reactome.org/PathwayBrowser/#/R-SSC-2730856 Autophosphorylation of PAK IEA Sus scrofa A0A286ZUQ0 R-SSC-2730858 https://reactome.org/PathwayBrowser/#/R-SSC-2730858 Autophosphorylation of BTK/ITK IEA Sus scrofa A0A286ZUQ0 R-SSC-2730870 https://reactome.org/PathwayBrowser/#/R-SSC-2730870 Phosphorylation of PIP2 to PIP3 by PI3K IEA Sus scrofa A0A286ZUQ0 R-SSC-2730889 https://reactome.org/PathwayBrowser/#/R-SSC-2730889 Recruitment of PAK to the membrane by binding active RAC1 IEA Sus scrofa A0A286ZUQ0 R-SSC-2730892 https://reactome.org/PathwayBrowser/#/R-SSC-2730892 Recruitment of VAV to p-SLP-76 IEA Sus scrofa A0A286ZUQ0 R-SSC-354165 https://reactome.org/PathwayBrowser/#/R-SSC-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Sus scrofa A0A286ZUQ0 R-SSC-392054 https://reactome.org/PathwayBrowser/#/R-SSC-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Sus scrofa A0A286ZUQ0 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa A0A286ZUQ0 R-SSC-453111 https://reactome.org/PathwayBrowser/#/R-SSC-453111 Phosphorylated SHC recruits GRB2:SOS1 IEA Sus scrofa A0A286ZUQ0 R-SSC-5654392 https://reactome.org/PathwayBrowser/#/R-SSC-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A286ZUQ0 R-SSC-5654402 https://reactome.org/PathwayBrowser/#/R-SSC-5654402 Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A286ZUQ0 R-SSC-5654413 https://reactome.org/PathwayBrowser/#/R-SSC-5654413 Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A286ZUQ0 R-SSC-5654423 https://reactome.org/PathwayBrowser/#/R-SSC-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Sus scrofa A0A286ZUQ0 R-SSC-5654426 https://reactome.org/PathwayBrowser/#/R-SSC-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A286ZUQ0 R-SSC-5654586 https://reactome.org/PathwayBrowser/#/R-SSC-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Sus scrofa A0A286ZUQ0 R-SSC-5654597 https://reactome.org/PathwayBrowser/#/R-SSC-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Sus scrofa A0A286ZUQ0 R-SSC-5654600 https://reactome.org/PathwayBrowser/#/R-SSC-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A286ZUQ0 R-SSC-5654618 https://reactome.org/PathwayBrowser/#/R-SSC-5654618 Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A286ZUQ0 R-SSC-5654647 https://reactome.org/PathwayBrowser/#/R-SSC-5654647 Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A286ZUQ0 R-SSC-5654663 https://reactome.org/PathwayBrowser/#/R-SSC-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A286ZUQ0 R-SSC-5654664 https://reactome.org/PathwayBrowser/#/R-SSC-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Sus scrofa A0A286ZUQ0 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A286ZUQ0 R-SSC-5685366 https://reactome.org/PathwayBrowser/#/R-SSC-5685366 GRB2-1:SOS1 binds p-Y-SHC IEA Sus scrofa A0A286ZUQ0 R-SSC-5686073 https://reactome.org/PathwayBrowser/#/R-SSC-5686073 GRB2-1:SOS1 binds p-3Y-SHC1 IEA Sus scrofa A0A286ZUQ0 R-SSC-5686074 https://reactome.org/PathwayBrowser/#/R-SSC-5686074 GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates IEA Sus scrofa A0A286ZUQ0 R-SSC-5686315 https://reactome.org/PathwayBrowser/#/R-SSC-5686315 GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates IEA Sus scrofa A0A286ZUQ0 R-SSC-74736 https://reactome.org/PathwayBrowser/#/R-SSC-74736 GRB2-1:SOS1 binds p-IRS1,p-IRS2 IEA Sus scrofa A0A286ZUQ0 R-SSC-74746 https://reactome.org/PathwayBrowser/#/R-SSC-74746 GRB2-1:SOS1 binds p-Y427-SHC1 IEA Sus scrofa A0A286ZUQ0 R-SSC-8851804 https://reactome.org/PathwayBrowser/#/R-SSC-8851804 Activated MET recruits GRB2-1:SOS1 IEA Sus scrofa A0A286ZUQ0 R-SSC-8851827 https://reactome.org/PathwayBrowser/#/R-SSC-8851827 RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 IEA Sus scrofa A0A286ZUQ0 R-SSC-8851859 https://reactome.org/PathwayBrowser/#/R-SSC-8851859 Activated MET binds RANBP9 and SOS1 IEA Sus scrofa A0A286ZUQ0 R-SSC-8851877 https://reactome.org/PathwayBrowser/#/R-SSC-8851877 RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET IEA Sus scrofa A0A286ZUQ0 R-SSC-8851899 https://reactome.org/PathwayBrowser/#/R-SSC-8851899 RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET IEA Sus scrofa A0A286ZUQ0 R-SSC-8851900 https://reactome.org/PathwayBrowser/#/R-SSC-8851900 SHC1-2 bound to MET recruits GRB2:SOS1 IEA Sus scrofa A0A286ZUQ0 R-SSC-8853734 https://reactome.org/PathwayBrowser/#/R-SSC-8853734 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 IEA Sus scrofa A0A286ZUQ0 R-SSC-8854899 https://reactome.org/PathwayBrowser/#/R-SSC-8854899 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 IEA Sus scrofa A0A286ZUQ0 R-SSC-8983384 https://reactome.org/PathwayBrowser/#/R-SSC-8983384 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 IEA Sus scrofa A0A286ZUQ0 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A286ZUQ0 R-SSC-9032073 https://reactome.org/PathwayBrowser/#/R-SSC-9032073 NTRK2-phosphorylated FRS2 binds GRB2 IEA Sus scrofa A0A286ZUQ0 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A286ZUQ0 R-SSC-9607301 https://reactome.org/PathwayBrowser/#/R-SSC-9607301 Active FLT3:GRB2 binds SOS1 IEA Sus scrofa A0A286ZUQ0 R-SSC-9607304 https://reactome.org/PathwayBrowser/#/R-SSC-9607304 SOS1-mediated nucleotide exchange of RAS downstream of FLT3 IEA Sus scrofa A0A286ZUQ0 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A286ZUQ0 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A286ZUQ8 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A286ZUS8 R-SSC-5362518 https://reactome.org/PathwayBrowser/#/R-SSC-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Sus scrofa A0A286ZUS8 R-SSC-74872 https://reactome.org/PathwayBrowser/#/R-SSC-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Sus scrofa A0A286ZUW0 R-SSC-449715 https://reactome.org/PathwayBrowser/#/R-SSC-449715 GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P IEA Sus scrofa A0A286ZUW5 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa A0A286ZUY9 R-SSC-481007 https://reactome.org/PathwayBrowser/#/R-SSC-481007 Exocytosis of platelet alpha granule contents IEA Sus scrofa A0A286ZUY9 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A286ZUY9 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A286ZV08 R-SSC-170846 https://reactome.org/PathwayBrowser/#/R-SSC-170846 TGFBR2 recruits TGFBR1 IEA Sus scrofa A0A286ZV08 R-SSC-170861 https://reactome.org/PathwayBrowser/#/R-SSC-170861 Dimeric TGF-beta-1 binds to the receptor IEA Sus scrofa A0A286ZV08 R-SSC-2395328 https://reactome.org/PathwayBrowser/#/R-SSC-2395328 LTBP1, LTBP3 bind TGF-Beta IEA Sus scrofa A0A286ZV08 R-SSC-481007 https://reactome.org/PathwayBrowser/#/R-SSC-481007 Exocytosis of platelet alpha granule contents IEA Sus scrofa A0A286ZV08 R-SSC-9839358 https://reactome.org/PathwayBrowser/#/R-SSC-9839358 Endocytosis of TGFBR3:ARRB complex IEA Sus scrofa A0A286ZV08 R-SSC-9839363 https://reactome.org/PathwayBrowser/#/R-SSC-9839363 TGFBR3 phosphorylation by TGFBR2 complex IEA Sus scrofa A0A286ZV08 R-SSC-9839368 https://reactome.org/PathwayBrowser/#/R-SSC-9839368 TGFBR3(1-783) binds to TGFB1,TGFB2 IEA Sus scrofa A0A286ZV08 R-SSC-9839377 https://reactome.org/PathwayBrowser/#/R-SSC-9839377 TGFB1,TGFB2 bind TGFBR3 IEA Sus scrofa A0A286ZV08 R-SSC-9839378 https://reactome.org/PathwayBrowser/#/R-SSC-9839378 TGFBR3 binding to ARRB1/2 IEA Sus scrofa A0A286ZV08 R-SSC-9839390 https://reactome.org/PathwayBrowser/#/R-SSC-9839390 TGFBR3 complex binds to TGFBR2 IEA Sus scrofa A0A286ZV08 R-SSC-9839401 https://reactome.org/PathwayBrowser/#/R-SSC-9839401 TGFBR3 degradation IEA Sus scrofa A0A286ZV08 R-SSC-9839402 https://reactome.org/PathwayBrowser/#/R-SSC-9839402 TGFBR3 binding to GIPC1 IEA Sus scrofa A0A286ZV27 R-SSC-5656064 https://reactome.org/PathwayBrowser/#/R-SSC-5656064 Activated FGFR1 binds FLRT1,2,3 IEA Sus scrofa A0A286ZV41 R-SSC-165758 https://reactome.org/PathwayBrowser/#/R-SSC-165758 Phosphorylation and inactivation of eEF2K by activated S6K1 IEA Sus scrofa A0A286ZV59 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A286ZV59 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A286ZV59 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A286ZV59 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A286ZV59 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A286ZV67 R-SSC-109701 https://reactome.org/PathwayBrowser/#/R-SSC-109701 PDPK1 binds PIP3 IEA Sus scrofa A0A286ZV67 R-SSC-109702 https://reactome.org/PathwayBrowser/#/R-SSC-109702 PDPK1 phosphorylates AKT2 IEA Sus scrofa A0A286ZV67 R-SSC-202164 https://reactome.org/PathwayBrowser/#/R-SSC-202164 Translocation of PDK1 to Plasma membrane IEA Sus scrofa A0A286ZV67 R-SSC-202222 https://reactome.org/PathwayBrowser/#/R-SSC-202222 Phosphorylation of PKC theta IEA Sus scrofa A0A286ZV67 R-SSC-202394 https://reactome.org/PathwayBrowser/#/R-SSC-202394 Translocation of CARMA1 to Plasma membrane IEA Sus scrofa A0A286ZV67 R-SSC-202437 https://reactome.org/PathwayBrowser/#/R-SSC-202437 Phosphorylation of CARMA1 IEA Sus scrofa A0A286ZV67 R-SSC-202443 https://reactome.org/PathwayBrowser/#/R-SSC-202443 Oligomerization of CARMA1 IEA Sus scrofa A0A286ZV67 R-SSC-202453 https://reactome.org/PathwayBrowser/#/R-SSC-202453 Auto-ubiquitination of TRAF6 IEA Sus scrofa A0A286ZV67 R-SSC-202459 https://reactome.org/PathwayBrowser/#/R-SSC-202459 Phosphorylation of Bcl10 IEA Sus scrofa A0A286ZV67 R-SSC-202466 https://reactome.org/PathwayBrowser/#/R-SSC-202466 Interaction of Bcl10 to CARMA1 IEA Sus scrofa A0A286ZV67 R-SSC-202472 https://reactome.org/PathwayBrowser/#/R-SSC-202472 Translocation of TRAF6 to CBM complex IEA Sus scrofa A0A286ZV67 R-SSC-202478 https://reactome.org/PathwayBrowser/#/R-SSC-202478 Interaction and oligomerization of MALT1 to Bcl10 IEA Sus scrofa A0A286ZV67 R-SSC-202489 https://reactome.org/PathwayBrowser/#/R-SSC-202489 Oligomerization of Bcl10 IEA Sus scrofa A0A286ZV67 R-SSC-202500 https://reactome.org/PathwayBrowser/#/R-SSC-202500 Activation of IKK complex IEA Sus scrofa A0A286ZV67 R-SSC-202510 https://reactome.org/PathwayBrowser/#/R-SSC-202510 Activation of TAK1-TAB2 complex IEA Sus scrofa A0A286ZV67 R-SSC-202534 https://reactome.org/PathwayBrowser/#/R-SSC-202534 Ubiquitination of NEMO by TRAF6 IEA Sus scrofa A0A286ZV67 R-SSC-2219524 https://reactome.org/PathwayBrowser/#/R-SSC-2219524 PDPK1 binds PIP2 IEA Sus scrofa A0A286ZV67 R-SSC-2316429 https://reactome.org/PathwayBrowser/#/R-SSC-2316429 PIP3 recruits PDPK1 to the membrane IEA Sus scrofa A0A286ZV67 R-SSC-432110 https://reactome.org/PathwayBrowser/#/R-SSC-432110 Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding IEA Sus scrofa A0A286ZV67 R-SSC-5218821 https://reactome.org/PathwayBrowser/#/R-SSC-5218821 PDK1 phosphorylates PKC IEA Sus scrofa A0A286ZV67 R-SSC-5623632 https://reactome.org/PathwayBrowser/#/R-SSC-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Sus scrofa A0A286ZV67 R-SSC-5623667 https://reactome.org/PathwayBrowser/#/R-SSC-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Sus scrofa A0A286ZV67 R-SSC-6795473 https://reactome.org/PathwayBrowser/#/R-SSC-6795473 PDPK1 phosphorylates SGK1 IEA Sus scrofa A0A286ZV67 R-SSC-9632858 https://reactome.org/PathwayBrowser/#/R-SSC-9632858 PRKCZ autophosphorylates downstream of estrogen stimulation IEA Sus scrofa A0A286ZV67 R-SSC-9632906 https://reactome.org/PathwayBrowser/#/R-SSC-9632906 PRKCZ recruits RAS in response to estrogen stimulation IEA Sus scrofa A0A286ZV67 R-SSC-9632910 https://reactome.org/PathwayBrowser/#/R-SSC-9632910 ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus IEA Sus scrofa A0A286ZV67 R-SSC-9632918 https://reactome.org/PathwayBrowser/#/R-SSC-9632918 PRKCZ stimulates RAS nucleotide exchange in response to estrogen IEA Sus scrofa A0A286ZV67 R-SSC-9860785 https://reactome.org/PathwayBrowser/#/R-SSC-9860785 PDPK1 (PDK1) phosphorylates PKN2 on threonine-816 IEA Sus scrofa A0A286ZV67 R-SSC-9860796 https://reactome.org/PathwayBrowser/#/R-SSC-9860796 Phosphorylation of PDPK1 on serine-241 IEA Sus scrofa A0A286ZV71 R-SSC-110133 https://reactome.org/PathwayBrowser/#/R-SSC-110133 (d)GDP + ADP <=> (d)GMP + ATP (GUK1) IEA Sus scrofa A0A286ZV71 R-SSC-73788 https://reactome.org/PathwayBrowser/#/R-SSC-73788 (d)GMP + ATP <=> (d)GDP + ADP (GUK1) IEA Sus scrofa A0A286ZV71 R-SSC-9748949 https://reactome.org/PathwayBrowser/#/R-SSC-9748949 GUK1 phosphorylates 6TGMP to 6TGDP IEA Sus scrofa A0A286ZV71 R-SSC-9748963 https://reactome.org/PathwayBrowser/#/R-SSC-9748963 GUK1 phosphorylates 6TdGMP to 6TdGDP IEA Sus scrofa A0A286ZV73 R-SSC-2161951 https://reactome.org/PathwayBrowser/#/R-SSC-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Sus scrofa A0A286ZV73 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa A0A286ZV73 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa A0A286ZV73 R-SSC-2309787 https://reactome.org/PathwayBrowser/#/R-SSC-2309787 Arachidonate is oxidised to PGG2 by PTGS2 IEA Sus scrofa A0A286ZV73 R-SSC-2314686 https://reactome.org/PathwayBrowser/#/R-SSC-2314686 ASA- acetylates PTGS2 IEA Sus scrofa A0A286ZV73 R-SSC-9018880 https://reactome.org/PathwayBrowser/#/R-SSC-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Sus scrofa A0A286ZV73 R-SSC-9020261 https://reactome.org/PathwayBrowser/#/R-SSC-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Sus scrofa A0A286ZV73 R-SSC-9026408 https://reactome.org/PathwayBrowser/#/R-SSC-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Sus scrofa A0A286ZV73 R-SSC-9027532 https://reactome.org/PathwayBrowser/#/R-SSC-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Sus scrofa A0A286ZV73 R-SSC-9027607 https://reactome.org/PathwayBrowser/#/R-SSC-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Sus scrofa A0A286ZV73 R-SSC-9027627 https://reactome.org/PathwayBrowser/#/R-SSC-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Sus scrofa A0A286ZV73 R-SSC-9028255 https://reactome.org/PathwayBrowser/#/R-SSC-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Sus scrofa A0A286ZV73 R-SSC-9716836 https://reactome.org/PathwayBrowser/#/R-SSC-9716836 PTGS2 dimer binds PTGS inhibitors IEA Sus scrofa A0A286ZV73 R-SSC-9716838 https://reactome.org/PathwayBrowser/#/R-SSC-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Sus scrofa A0A286ZV83 R-SSC-203973 https://reactome.org/PathwayBrowser/#/R-SSC-203973 Vesicle budding IEA Sus scrofa A0A286ZV83 R-SSC-204008 https://reactome.org/PathwayBrowser/#/R-SSC-204008 SEC31:SEC13 and v-SNARE recruitment IEA Sus scrofa A0A286ZV83 R-SSC-5694417 https://reactome.org/PathwayBrowser/#/R-SSC-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Sus scrofa A0A286ZV90 R-SSC-430021 https://reactome.org/PathwayBrowser/#/R-SSC-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Sus scrofa A0A286ZV95 R-SSC-203973 https://reactome.org/PathwayBrowser/#/R-SSC-203973 Vesicle budding IEA Sus scrofa A0A286ZV95 R-SSC-204008 https://reactome.org/PathwayBrowser/#/R-SSC-204008 SEC31:SEC13 and v-SNARE recruitment IEA Sus scrofa A0A286ZV95 R-SSC-5694409 https://reactome.org/PathwayBrowser/#/R-SSC-5694409 Nucleotide exchange on RAB1 IEA Sus scrofa A0A286ZV95 R-SSC-5694410 https://reactome.org/PathwayBrowser/#/R-SSC-5694410 TMED2:TMED10 tetramer binds GPI anchored proteins IEA Sus scrofa A0A286ZV95 R-SSC-5694417 https://reactome.org/PathwayBrowser/#/R-SSC-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Sus scrofa A0A286ZV95 R-SSC-5694418 https://reactome.org/PathwayBrowser/#/R-SSC-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Sus scrofa A0A286ZV95 R-SSC-5694446 https://reactome.org/PathwayBrowser/#/R-SSC-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Sus scrofa A0A286ZV95 R-SSC-5694522 https://reactome.org/PathwayBrowser/#/R-SSC-5694522 Inner coat assembly and cargo binding IEA Sus scrofa A0A286ZV95 R-SSC-5694527 https://reactome.org/PathwayBrowser/#/R-SSC-5694527 Loss of SAR1B GTPase IEA Sus scrofa A0A286ZV95 R-SSC-6807875 https://reactome.org/PathwayBrowser/#/R-SSC-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Sus scrofa A0A286ZV95 R-SSC-6807877 https://reactome.org/PathwayBrowser/#/R-SSC-6807877 ARFGAPs stimulate ARF GTPase activity IEA Sus scrofa A0A286ZV95 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa A0A286ZV95 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A286ZV95 R-SSC-6809011 https://reactome.org/PathwayBrowser/#/R-SSC-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Sus scrofa A0A286ZV95 R-SSC-6811417 https://reactome.org/PathwayBrowser/#/R-SSC-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Sus scrofa A0A286ZV95 R-SSC-6811418 https://reactome.org/PathwayBrowser/#/R-SSC-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Sus scrofa A0A286ZV95 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa A0A286ZV95 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa A0A286ZVC9 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A286ZVD0 R-SSC-1955380 https://reactome.org/PathwayBrowser/#/R-SSC-1955380 TIMM9:TIMM10 transfers proteins to TIMM22 IEA Sus scrofa A0A286ZVF1 R-SSC-5682385 https://reactome.org/PathwayBrowser/#/R-SSC-5682385 The phagophore extends from the PIP3-enriched structure IEA Sus scrofa A0A286ZVF1 R-SSC-9840807 https://reactome.org/PathwayBrowser/#/R-SSC-9840807 OPTN binds ATG9A IEA Sus scrofa A0A286ZVF4 R-SSC-8954398 https://reactome.org/PathwayBrowser/#/R-SSC-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Sus scrofa A0A286ZVG1 R-SSC-8948139 https://reactome.org/PathwayBrowser/#/R-SSC-8948139 p-S13-FUNDC1 is dephosphorylated by PGAM5 IEA Sus scrofa A0A286ZVG1 R-SSC-9861725 https://reactome.org/PathwayBrowser/#/R-SSC-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Sus scrofa A0A286ZVG7 R-SSC-1564112 https://reactome.org/PathwayBrowser/#/R-SSC-1564112 Collagen type VI degradation by MMP2,9,11 IEA Sus scrofa A0A286ZVG7 R-SSC-1614460 https://reactome.org/PathwayBrowser/#/R-SSC-1614460 Dimerization of procollagen type VI IEA Sus scrofa A0A286ZVG7 R-SSC-1614461 https://reactome.org/PathwayBrowser/#/R-SSC-1614461 Tetramerization of procollagen VI IEA Sus scrofa A0A286ZVG7 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa A0A286ZVG7 R-SSC-1981104 https://reactome.org/PathwayBrowser/#/R-SSC-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Sus scrofa A0A286ZVG7 R-SSC-1981120 https://reactome.org/PathwayBrowser/#/R-SSC-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Sus scrofa A0A286ZVG7 R-SSC-1981128 https://reactome.org/PathwayBrowser/#/R-SSC-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Sus scrofa A0A286ZVG7 R-SSC-1981157 https://reactome.org/PathwayBrowser/#/R-SSC-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Sus scrofa A0A286ZVG7 R-SSC-2002460 https://reactome.org/PathwayBrowser/#/R-SSC-2002460 P4HB binds Collagen chains IEA Sus scrofa A0A286ZVG7 R-SSC-2089971 https://reactome.org/PathwayBrowser/#/R-SSC-2089971 Secretion of collagens IEA Sus scrofa A0A286ZVG7 R-SSC-2213207 https://reactome.org/PathwayBrowser/#/R-SSC-2213207 Formation of collagen networks IEA Sus scrofa A0A286ZVG7 R-SSC-2327695 https://reactome.org/PathwayBrowser/#/R-SSC-2327695 Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 IEA Sus scrofa A0A286ZVG7 R-SSC-2327909 https://reactome.org/PathwayBrowser/#/R-SSC-2327909 DCN binds collagen I, II, III, VI fibrils IEA Sus scrofa A0A286ZVG7 R-SSC-2466106 https://reactome.org/PathwayBrowser/#/R-SSC-2466106 BGN binds Collagen types I, VI, (IX) IEA Sus scrofa A0A286ZVG7 R-SSC-382054 https://reactome.org/PathwayBrowser/#/R-SSC-382054 PDGF binds to extracellular matrix proteins IEA Sus scrofa A0A286ZVG7 R-SSC-4084903 https://reactome.org/PathwayBrowser/#/R-SSC-4084903 Collagen types VI, IX bind integrin alpha10beta1 IEA Sus scrofa A0A286ZVG7 R-SSC-8944247 https://reactome.org/PathwayBrowser/#/R-SSC-8944247 Association of procollagen type VI IEA Sus scrofa A0A286ZVG7 R-SSC-8948219 https://reactome.org/PathwayBrowser/#/R-SSC-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A286ZVG7 R-SSC-8948222 https://reactome.org/PathwayBrowser/#/R-SSC-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A286ZVG7 R-SSC-8948224 https://reactome.org/PathwayBrowser/#/R-SSC-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A286ZVG7 R-SSC-8948228 https://reactome.org/PathwayBrowser/#/R-SSC-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A286ZVG7 R-SSC-8948231 https://reactome.org/PathwayBrowser/#/R-SSC-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A286ZVG7 R-SSC-8948232 https://reactome.org/PathwayBrowser/#/R-SSC-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Sus scrofa A0A286ZVG7 R-SSC-8948234 https://reactome.org/PathwayBrowser/#/R-SSC-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Sus scrofa A0A286ZVH1 R-SSC-429036 https://reactome.org/PathwayBrowser/#/R-SSC-429036 SLC2A9 transports Fru, Glc, urate IEA Sus scrofa A0A286ZVH7 R-SSC-3371353 https://reactome.org/PathwayBrowser/#/R-SSC-3371353 Soluble TNF-α binds TNFR1 IEA Sus scrofa A0A286ZVH7 R-SSC-5357757 https://reactome.org/PathwayBrowser/#/R-SSC-5357757 BIRC(cIAP1/2) ubiquitinates RIPK1 IEA Sus scrofa A0A286ZVH7 R-SSC-5357776 https://reactome.org/PathwayBrowser/#/R-SSC-5357776 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG IEA Sus scrofa A0A286ZVH7 R-SSC-5357780 https://reactome.org/PathwayBrowser/#/R-SSC-5357780 TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) IEA Sus scrofa A0A286ZVH7 R-SSC-5357845 https://reactome.org/PathwayBrowser/#/R-SSC-5357845 K63polyUb-RIPK1 is deubiquitinated IEA Sus scrofa A0A286ZVH7 R-SSC-5357860 https://reactome.org/PathwayBrowser/#/R-SSC-5357860 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex IEA Sus scrofa A0A286ZVH7 R-SSC-5357928 https://reactome.org/PathwayBrowser/#/R-SSC-5357928 CLIP3 and CYLD bind TNF signaling complex IEA Sus scrofa A0A286ZVH7 R-SSC-5626953 https://reactome.org/PathwayBrowser/#/R-SSC-5626953 TNF-α:TNFR1 binds DENN/MADD IEA Sus scrofa A0A286ZVH7 R-SSC-5626981 https://reactome.org/PathwayBrowser/#/R-SSC-5626981 TNF-α:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 IEA Sus scrofa A0A286ZVH7 R-SSC-5626982 https://reactome.org/PathwayBrowser/#/R-SSC-5626982 TNF-α:TNFR1:NSMAF binds RACK1 IEA Sus scrofa A0A286ZVH7 R-SSC-5626988 https://reactome.org/PathwayBrowser/#/R-SSC-5626988 TNF-α:TNFR1 binds NSMAF IEA Sus scrofa A0A286ZVH7 R-SSC-5634221 https://reactome.org/PathwayBrowser/#/R-SSC-5634221 TRAF1 binds TRAF2 within TNFR1 signaling complex IEA Sus scrofa A0A286ZVH7 R-SSC-5669097 https://reactome.org/PathwayBrowser/#/R-SSC-5669097 LTA trimer binds TNFRSF1A,1B,14 IEA Sus scrofa A0A286ZVH7 R-SSC-5693055 https://reactome.org/PathwayBrowser/#/R-SSC-5693055 TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes IEA Sus scrofa A0A286ZVH7 R-SSC-5693108 https://reactome.org/PathwayBrowser/#/R-SSC-5693108 TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains IEA Sus scrofa A0A286ZVH7 R-SSC-83582 https://reactome.org/PathwayBrowser/#/R-SSC-83582 TRADD:TRAF2:RIP1 dissociates from TNF-α:TNFR1 IEA Sus scrofa A0A286ZVH7 R-SSC-83656 https://reactome.org/PathwayBrowser/#/R-SSC-83656 TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 IEA Sus scrofa A0A286ZVH7 R-SSC-83660 https://reactome.org/PathwayBrowser/#/R-SSC-83660 Membrane-anchored TNF-α binds TNFR1 IEA Sus scrofa A0A286ZVH7 R-SSC-9793679 https://reactome.org/PathwayBrowser/#/R-SSC-9793679 LUBAC ubiquitinates RIPK1 at K627 IEA Sus scrofa A0A286ZVH7 R-SSC-9793680 https://reactome.org/PathwayBrowser/#/R-SSC-9793680 OPTN binds polyUb-RIPK1 within the TNFR1 complex IEA Sus scrofa A0A286ZVH7 R-SSC-9796342 https://reactome.org/PathwayBrowser/#/R-SSC-9796342 MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 IEA Sus scrofa A0A286ZVH7 R-SSC-9796346 https://reactome.org/PathwayBrowser/#/R-SSC-9796346 MIB2 ubiquitinates RIPK1 at K377, K604, K634 IEA Sus scrofa A0A286ZVH7 R-SSC-9796379 https://reactome.org/PathwayBrowser/#/R-SSC-9796379 CYLD:SPATA2:LUBAC binds TNFR1 signaling complex IEA Sus scrofa A0A286ZVH7 R-SSC-9817362 https://reactome.org/PathwayBrowser/#/R-SSC-9817362 SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex IEA Sus scrofa A0A286ZVH7 R-SSC-9817397 https://reactome.org/PathwayBrowser/#/R-SSC-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Sus scrofa A0A286ZVH7 R-SSC-9817400 https://reactome.org/PathwayBrowser/#/R-SSC-9817400 CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex IEA Sus scrofa A0A286ZVH7 R-SSC-9817411 https://reactome.org/PathwayBrowser/#/R-SSC-9817411 TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex IEA Sus scrofa A0A286ZVH7 R-SSC-9818789 https://reactome.org/PathwayBrowser/#/R-SSC-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 IEA Sus scrofa A0A286ZVH7 R-SSC-9818975 https://reactome.org/PathwayBrowser/#/R-SSC-9818975 CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex IEA Sus scrofa A0A286ZVH7 R-SSC-9824874 https://reactome.org/PathwayBrowser/#/R-SSC-9824874 OPTN recruits CYLD to the TNFR1 complex IEA Sus scrofa A0A286ZVH8 R-SSC-2197646 https://reactome.org/PathwayBrowser/#/R-SSC-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Sus scrofa A0A286ZVH8 R-SSC-2512800 https://reactome.org/PathwayBrowser/#/R-SSC-2512800 SCARB1:ligand is endocytosed IEA Sus scrofa A0A286ZVH8 R-SSC-349637 https://reactome.org/PathwayBrowser/#/R-SSC-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Sus scrofa A0A286ZVH8 R-SSC-349638 https://reactome.org/PathwayBrowser/#/R-SSC-349638 Disassembly of SR-BI-bound spherical HDL IEA Sus scrofa A0A286ZVI5 R-SSC-163096 https://reactome.org/PathwayBrowser/#/R-SSC-163096 Recruitment of Telomerase RNP to the Telomeric Chromosome End IEA Sus scrofa A0A286ZVI5 R-SSC-5694421 https://reactome.org/PathwayBrowser/#/R-SSC-5694421 PP6 dephosphorylates SEC24 IEA Sus scrofa A0A286ZVI5 R-SSC-9686524 https://reactome.org/PathwayBrowser/#/R-SSC-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Sus scrofa A0A286ZVJ2 R-SSC-354060 https://reactome.org/PathwayBrowser/#/R-SSC-354060 Translocation of RIAM to plasma membrane IEA Sus scrofa A0A286ZVJ2 R-SSC-354073 https://reactome.org/PathwayBrowser/#/R-SSC-354073 Autophosphorylation of PTK2 at Y397 IEA Sus scrofa A0A286ZVJ2 R-SSC-354077 https://reactome.org/PathwayBrowser/#/R-SSC-354077 Integrin alphaIIb beta3 activation IEA Sus scrofa A0A286ZVJ2 R-SSC-354087 https://reactome.org/PathwayBrowser/#/R-SSC-354087 Recruitment of GRB2 to p-PTK2 IEA Sus scrofa A0A286ZVJ2 R-SSC-354097 https://reactome.org/PathwayBrowser/#/R-SSC-354097 Activation of Talin IEA Sus scrofa A0A286ZVJ2 R-SSC-354124 https://reactome.org/PathwayBrowser/#/R-SSC-354124 Phosphorylation of pPTK2 by SRC IEA Sus scrofa A0A286ZVJ2 R-SSC-354149 https://reactome.org/PathwayBrowser/#/R-SSC-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Sus scrofa A0A286ZVJ2 R-SSC-354165 https://reactome.org/PathwayBrowser/#/R-SSC-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Sus scrofa A0A286ZVJ2 R-SSC-354173 https://reactome.org/PathwayBrowser/#/R-SSC-354173 Activation of Rap1 by cytosolic GEFs IEA Sus scrofa A0A286ZVJ2 R-SSC-372693 https://reactome.org/PathwayBrowser/#/R-SSC-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Sus scrofa A0A286ZVJ2 R-SSC-372697 https://reactome.org/PathwayBrowser/#/R-SSC-372697 Crk binding to p130cas IEA Sus scrofa A0A286ZVJ2 R-SSC-372705 https://reactome.org/PathwayBrowser/#/R-SSC-372705 Recruitment of BCAR1 to PTK2 complex IEA Sus scrofa A0A286ZVJ2 R-SSC-377640 https://reactome.org/PathwayBrowser/#/R-SSC-377640 Autophosphorylation of SRC IEA Sus scrofa A0A286ZVJ2 R-SSC-377641 https://reactome.org/PathwayBrowser/#/R-SSC-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Sus scrofa A0A286ZVJ2 R-SSC-377643 https://reactome.org/PathwayBrowser/#/R-SSC-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Sus scrofa A0A286ZVJ2 R-SSC-377644 https://reactome.org/PathwayBrowser/#/R-SSC-377644 Release of CSK from SRC IEA Sus scrofa A0A286ZVJ2 R-SSC-392513 https://reactome.org/PathwayBrowser/#/R-SSC-392513 Rap1 signal termination by Rap1GAPs IEA Sus scrofa A0A286ZVJ2 R-SSC-429415 https://reactome.org/PathwayBrowser/#/R-SSC-429415 SYK binds to integrin alphaIIb beta3 IEA Sus scrofa A0A286ZVJ2 R-SSC-429441 https://reactome.org/PathwayBrowser/#/R-SSC-429441 SYK activation by SRC IEA Sus scrofa A0A286ZVJ2 R-SSC-432096 https://reactome.org/PathwayBrowser/#/R-SSC-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Sus scrofa A0A286ZVJ2 R-SSC-443905 https://reactome.org/PathwayBrowser/#/R-SSC-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Sus scrofa A0A286ZVJ2 R-SSC-443910 https://reactome.org/PathwayBrowser/#/R-SSC-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Sus scrofa A0A286ZVJ2 R-SSC-5672972 https://reactome.org/PathwayBrowser/#/R-SSC-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Sus scrofa A0A286ZVJ2 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa A0A286ZVJ2 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa A0A286ZVJ2 R-SSC-5672980 https://reactome.org/PathwayBrowser/#/R-SSC-5672980 Dissociation of RAS:RAF complex IEA Sus scrofa A0A286ZVJ2 R-SSC-6798739 https://reactome.org/PathwayBrowser/#/R-SSC-6798739 Exocytosis of azurophil granule membrane proteins IEA Sus scrofa A0A286ZVJ2 R-SSC-8875568 https://reactome.org/PathwayBrowser/#/R-SSC-8875568 RAPGEF1 activates RAP1 IEA Sus scrofa A0A286ZVJ2 R-SSC-939265 https://reactome.org/PathwayBrowser/#/R-SSC-939265 Activation of Rap1 by membrane-associated GEFs IEA Sus scrofa A0A286ZVJ2 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa A0A286ZVJ2 R-SSC-9657603 https://reactome.org/PathwayBrowser/#/R-SSC-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Sus scrofa A0A286ZVJ2 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa A0A286ZVJ2 R-SSC-9657608 https://reactome.org/PathwayBrowser/#/R-SSC-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Sus scrofa A0A286ZVK1 R-SSC-158145 https://reactome.org/PathwayBrowser/#/R-SSC-158145 factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex IEA Sus scrofa A0A286ZVK1 R-SSC-158300 https://reactome.org/PathwayBrowser/#/R-SSC-158300 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (XIIa catalyst) IEA Sus scrofa A0A286ZVK1 R-SSC-158333 https://reactome.org/PathwayBrowser/#/R-SSC-158333 factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) IEA Sus scrofa A0A286ZVK1 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa A0A286ZVL7 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A286ZVN4 R-SSC-1013012 https://reactome.org/PathwayBrowser/#/R-SSC-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Sus scrofa A0A286ZVN4 R-SSC-1013013 https://reactome.org/PathwayBrowser/#/R-SSC-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Sus scrofa A0A286ZVN4 R-SSC-1013020 https://reactome.org/PathwayBrowser/#/R-SSC-1013020 Activation of GIRK/Kir3 Channels IEA Sus scrofa A0A286ZVN4 R-SSC-112271 https://reactome.org/PathwayBrowser/#/R-SSC-112271 The receptor:G-protein complex dissociates IEA Sus scrofa A0A286ZVN4 R-SSC-114552 https://reactome.org/PathwayBrowser/#/R-SSC-114552 Thrombin-activated PARs activate G12/13 IEA Sus scrofa A0A286ZVN4 R-SSC-114558 https://reactome.org/PathwayBrowser/#/R-SSC-114558 Thrombin-activated PARs activate Gq IEA Sus scrofa A0A286ZVN4 R-SSC-167408 https://reactome.org/PathwayBrowser/#/R-SSC-167408 The high affinity receptor complex binds to G-protein IEA Sus scrofa A0A286ZVN4 R-SSC-167419 https://reactome.org/PathwayBrowser/#/R-SSC-167419 The receptor:G-protein complex releases GDP IEA Sus scrofa A0A286ZVN4 R-SSC-167429 https://reactome.org/PathwayBrowser/#/R-SSC-167429 The receptor:G-protein complex binds GTP IEA Sus scrofa A0A286ZVN4 R-SSC-167433 https://reactome.org/PathwayBrowser/#/R-SSC-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Sus scrofa A0A286ZVN4 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa A0A286ZVN4 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A286ZVN4 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A286ZVN4 R-SSC-381612 https://reactome.org/PathwayBrowser/#/R-SSC-381612 GLP1R binds GLP1 IEA Sus scrofa A0A286ZVN4 R-SSC-392187 https://reactome.org/PathwayBrowser/#/R-SSC-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Sus scrofa A0A286ZVN4 R-SSC-392195 https://reactome.org/PathwayBrowser/#/R-SSC-392195 Gi activation by P2Y purinoceptor 12 IEA Sus scrofa A0A286ZVN4 R-SSC-392202 https://reactome.org/PathwayBrowser/#/R-SSC-392202 Dissociation of the P2Y purinoceptor 12:Gi complex IEA Sus scrofa A0A286ZVN4 R-SSC-392295 https://reactome.org/PathwayBrowser/#/R-SSC-392295 Gbeta:gamma recruits PI3K gamma IEA Sus scrofa A0A286ZVN4 R-SSC-392300 https://reactome.org/PathwayBrowser/#/R-SSC-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Sus scrofa A0A286ZVN4 R-SSC-392870 https://reactome.org/PathwayBrowser/#/R-SSC-392870 Gs activation by prostacyclin receptor IEA Sus scrofa A0A286ZVN4 R-SSC-3965444 https://reactome.org/PathwayBrowser/#/R-SSC-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Sus scrofa A0A286ZVN4 R-SSC-3965447 https://reactome.org/PathwayBrowser/#/R-SSC-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Sus scrofa A0A286ZVN4 R-SSC-396996 https://reactome.org/PathwayBrowser/#/R-SSC-396996 Thrombin-activated PARs binds G-protein Gq IEA Sus scrofa A0A286ZVN4 R-SSC-397835 https://reactome.org/PathwayBrowser/#/R-SSC-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Sus scrofa A0A286ZVN4 R-SSC-397891 https://reactome.org/PathwayBrowser/#/R-SSC-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Sus scrofa A0A286ZVN4 R-SSC-398040 https://reactome.org/PathwayBrowser/#/R-SSC-398040 Gbeta:gamma activation of PLC beta IEA Sus scrofa A0A286ZVN4 R-SSC-398193 https://reactome.org/PathwayBrowser/#/R-SSC-398193 PLC beta-mediated PIP2 hydrolysis IEA Sus scrofa A0A286ZVN4 R-SSC-400037 https://reactome.org/PathwayBrowser/#/R-SSC-400037 Gi,Go Heterotrimeric G-protein complex dissociates IEA Sus scrofa A0A286ZVN4 R-SSC-400092 https://reactome.org/PathwayBrowser/#/R-SSC-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Sus scrofa A0A286ZVN4 R-SSC-400097 https://reactome.org/PathwayBrowser/#/R-SSC-400097 G-beta:G-gamma inhibits Adenylate cyclase IEA Sus scrofa A0A286ZVN4 R-SSC-418576 https://reactome.org/PathwayBrowser/#/R-SSC-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Sus scrofa A0A286ZVN4 R-SSC-420883 https://reactome.org/PathwayBrowser/#/R-SSC-420883 Opsins act as GEFs for G alpha-t IEA Sus scrofa A0A286ZVN4 R-SSC-428749 https://reactome.org/PathwayBrowser/#/R-SSC-428749 Activated TP receptor binds G-proten Gq IEA Sus scrofa A0A286ZVN4 R-SSC-428750 https://reactome.org/PathwayBrowser/#/R-SSC-428750 Gq activation by TP receptor IEA Sus scrofa A0A286ZVN4 R-SSC-428752 https://reactome.org/PathwayBrowser/#/R-SSC-428752 Dissociation of the TP:Gq complex IEA Sus scrofa A0A286ZVN4 R-SSC-428909 https://reactome.org/PathwayBrowser/#/R-SSC-428909 Activated TP receptor binds G-protein G13 IEA Sus scrofa A0A286ZVN4 R-SSC-428917 https://reactome.org/PathwayBrowser/#/R-SSC-428917 G13 activation by TP receptor IEA Sus scrofa A0A286ZVN4 R-SSC-428918 https://reactome.org/PathwayBrowser/#/R-SSC-428918 Dissociation of the TP:G13 complex IEA Sus scrofa A0A286ZVN4 R-SSC-432195 https://reactome.org/PathwayBrowser/#/R-SSC-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Sus scrofa A0A286ZVN4 R-SSC-500717 https://reactome.org/PathwayBrowser/#/R-SSC-500717 Activation of GRIK3 homomer IEA Sus scrofa A0A286ZVN4 R-SSC-6814418 https://reactome.org/PathwayBrowser/#/R-SSC-6814418 PDCL promotes formation of G-beta:G-gamma heterodimers IEA Sus scrofa A0A286ZVN4 R-SSC-749446 https://reactome.org/PathwayBrowser/#/R-SSC-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Sus scrofa A0A286ZVN4 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A286ZVN4 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A286ZVN4 R-SSC-749453 https://reactome.org/PathwayBrowser/#/R-SSC-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Sus scrofa A0A286ZVN4 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A286ZVN4 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A286ZVN4 R-SSC-750988 https://reactome.org/PathwayBrowser/#/R-SSC-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Sus scrofa A0A286ZVN4 R-SSC-750993 https://reactome.org/PathwayBrowser/#/R-SSC-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Sus scrofa A0A286ZVN4 R-SSC-751001 https://reactome.org/PathwayBrowser/#/R-SSC-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Sus scrofa A0A286ZVN4 R-SSC-751019 https://reactome.org/PathwayBrowser/#/R-SSC-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Sus scrofa A0A286ZVN4 R-SSC-751024 https://reactome.org/PathwayBrowser/#/R-SSC-751024 The Ligand:GPCR:Gz complex dissociates IEA Sus scrofa A0A286ZVN4 R-SSC-751027 https://reactome.org/PathwayBrowser/#/R-SSC-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Sus scrofa A0A286ZVN4 R-SSC-751029 https://reactome.org/PathwayBrowser/#/R-SSC-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Sus scrofa A0A286ZVN4 R-SSC-751039 https://reactome.org/PathwayBrowser/#/R-SSC-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Sus scrofa A0A286ZVN4 R-SSC-8850560 https://reactome.org/PathwayBrowser/#/R-SSC-8850560 G-protein alpha releases G-protein heterotrimer from PDCL IEA Sus scrofa A0A286ZVN4 R-SSC-8964241 https://reactome.org/PathwayBrowser/#/R-SSC-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Sus scrofa A0A286ZVN4 R-SSC-8964271 https://reactome.org/PathwayBrowser/#/R-SSC-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Sus scrofa A0A286ZVN4 R-SSC-8964317 https://reactome.org/PathwayBrowser/#/R-SSC-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Sus scrofa A0A286ZVN4 R-SSC-8964599 https://reactome.org/PathwayBrowser/#/R-SSC-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Sus scrofa A0A286ZVN4 R-SSC-8964604 https://reactome.org/PathwayBrowser/#/R-SSC-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Sus scrofa A0A286ZVN4 R-SSC-8964605 https://reactome.org/PathwayBrowser/#/R-SSC-8964605 PAK1:ARHGEF6 complex binds G-protein beta-gamma complex IEA Sus scrofa A0A286ZVN4 R-SSC-8964614 https://reactome.org/PathwayBrowser/#/R-SSC-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Sus scrofa A0A286ZVN4 R-SSC-8964634 https://reactome.org/PathwayBrowser/#/R-SSC-8964634 CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex IEA Sus scrofa A0A286ZVN4 R-SSC-8982637 https://reactome.org/PathwayBrowser/#/R-SSC-8982637 Opsins binds G alpha-t IEA Sus scrofa A0A286ZVN4 R-SSC-8982640 https://reactome.org/PathwayBrowser/#/R-SSC-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Sus scrofa A0A286ZVN4 R-SSC-9021596 https://reactome.org/PathwayBrowser/#/R-SSC-9021596 Membrane estrogen receptors bind SRC IEA Sus scrofa A0A286ZVN4 R-SSC-9021600 https://reactome.org/PathwayBrowser/#/R-SSC-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Sus scrofa A0A286ZVN4 R-SSC-9021601 https://reactome.org/PathwayBrowser/#/R-SSC-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Sus scrofa A0A286ZVN4 R-SSC-9036301 https://reactome.org/PathwayBrowser/#/R-SSC-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Sus scrofa A0A286ZVN4 R-SSC-9036307 https://reactome.org/PathwayBrowser/#/R-SSC-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Sus scrofa A0A286ZVN4 R-SSC-9728664 https://reactome.org/PathwayBrowser/#/R-SSC-9728664 GLP1R binds GLP1R agonists IEA Sus scrofa A0A286ZVN4 R-SSC-9861324 https://reactome.org/PathwayBrowser/#/R-SSC-9861324 ADM:CALCRL:RAMP2:G-alpha(s):GDP:G-beta:G-gamma exchanges GDP for GTP IEA Sus scrofa A0A286ZVQ0 R-SSC-5690043 https://reactome.org/PathwayBrowser/#/R-SSC-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa A0A286ZVQ0 R-SSC-5690066 https://reactome.org/PathwayBrowser/#/R-SSC-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa A0A286ZVQ0 R-SSC-9033235 https://reactome.org/PathwayBrowser/#/R-SSC-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A286ZVQ0 R-SSC-9033236 https://reactome.org/PathwayBrowser/#/R-SSC-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Sus scrofa A0A286ZVQ0 R-SSC-9838035 https://reactome.org/PathwayBrowser/#/R-SSC-9838035 CLPXP binds mitochondrial matrix proteins IEA Sus scrofa A0A286ZVQ0 R-SSC-9838081 https://reactome.org/PathwayBrowser/#/R-SSC-9838081 LONP1 degrades mitochondrial matrix proteins IEA Sus scrofa A0A286ZVQ0 R-SSC-9838093 https://reactome.org/PathwayBrowser/#/R-SSC-9838093 LONP1 binds mitochondrial matrix proteins IEA Sus scrofa A0A286ZVQ0 R-SSC-9838289 https://reactome.org/PathwayBrowser/#/R-SSC-9838289 CLPXP degrades mitochondrial matrix proteins IEA Sus scrofa A0A286ZVQ9 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa A0A286ZVQ9 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A286ZVQ9 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A286ZVQ9 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A286ZVQ9 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa A0A286ZVU8 R-SSC-354060 https://reactome.org/PathwayBrowser/#/R-SSC-354060 Translocation of RIAM to plasma membrane IEA Sus scrofa A0A286ZVU8 R-SSC-354073 https://reactome.org/PathwayBrowser/#/R-SSC-354073 Autophosphorylation of PTK2 at Y397 IEA Sus scrofa A0A286ZVU8 R-SSC-354077 https://reactome.org/PathwayBrowser/#/R-SSC-354077 Integrin alphaIIb beta3 activation IEA Sus scrofa A0A286ZVU8 R-SSC-354087 https://reactome.org/PathwayBrowser/#/R-SSC-354087 Recruitment of GRB2 to p-PTK2 IEA Sus scrofa A0A286ZVU8 R-SSC-354097 https://reactome.org/PathwayBrowser/#/R-SSC-354097 Activation of Talin IEA Sus scrofa A0A286ZVU8 R-SSC-354124 https://reactome.org/PathwayBrowser/#/R-SSC-354124 Phosphorylation of pPTK2 by SRC IEA Sus scrofa A0A286ZVU8 R-SSC-354149 https://reactome.org/PathwayBrowser/#/R-SSC-354149 Interaction of integrin alphaIIb beta3 with Fibrinogen IEA Sus scrofa A0A286ZVU8 R-SSC-354165 https://reactome.org/PathwayBrowser/#/R-SSC-354165 Interaction of SOS with GRB2 bound to FADK1 IEA Sus scrofa A0A286ZVU8 R-SSC-372693 https://reactome.org/PathwayBrowser/#/R-SSC-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Sus scrofa A0A286ZVU8 R-SSC-372697 https://reactome.org/PathwayBrowser/#/R-SSC-372697 Crk binding to p130cas IEA Sus scrofa A0A286ZVU8 R-SSC-372705 https://reactome.org/PathwayBrowser/#/R-SSC-372705 Recruitment of BCAR1 to PTK2 complex IEA Sus scrofa A0A286ZVU8 R-SSC-377640 https://reactome.org/PathwayBrowser/#/R-SSC-377640 Autophosphorylation of SRC IEA Sus scrofa A0A286ZVU8 R-SSC-377641 https://reactome.org/PathwayBrowser/#/R-SSC-377641 Clustering of Integrin alphaIIb beta3 complexes IEA Sus scrofa A0A286ZVU8 R-SSC-377643 https://reactome.org/PathwayBrowser/#/R-SSC-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Sus scrofa A0A286ZVU8 R-SSC-377644 https://reactome.org/PathwayBrowser/#/R-SSC-377644 Release of CSK from SRC IEA Sus scrofa A0A286ZVU8 R-SSC-429415 https://reactome.org/PathwayBrowser/#/R-SSC-429415 SYK binds to integrin alphaIIb beta3 IEA Sus scrofa A0A286ZVU8 R-SSC-429441 https://reactome.org/PathwayBrowser/#/R-SSC-429441 SYK activation by SRC IEA Sus scrofa A0A286ZVU8 R-SSC-432096 https://reactome.org/PathwayBrowser/#/R-SSC-432096 Activated integrin alphaIIb beta3 binds SHC1 IEA Sus scrofa A0A286ZVU8 R-SSC-443905 https://reactome.org/PathwayBrowser/#/R-SSC-443905 SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow IEA Sus scrofa A0A286ZVU8 R-SSC-443910 https://reactome.org/PathwayBrowser/#/R-SSC-443910 SHC1 dissociates from integrin alphaIIb beta3 IEA Sus scrofa A0A286ZVU8 R-SSC-5672972 https://reactome.org/PathwayBrowser/#/R-SSC-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Sus scrofa A0A286ZVU8 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa A0A286ZVU8 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa A0A286ZVU8 R-SSC-5672980 https://reactome.org/PathwayBrowser/#/R-SSC-5672980 Dissociation of RAS:RAF complex IEA Sus scrofa A0A286ZVU8 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa A0A286ZVU8 R-SSC-9657603 https://reactome.org/PathwayBrowser/#/R-SSC-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Sus scrofa A0A286ZVU8 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa A0A286ZVU8 R-SSC-9657608 https://reactome.org/PathwayBrowser/#/R-SSC-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Sus scrofa A0A286ZVW4 R-SSC-197198 https://reactome.org/PathwayBrowser/#/R-SSC-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Sus scrofa A0A286ZVY2 R-SSC-1295604 https://reactome.org/PathwayBrowser/#/R-SSC-1295604 B-RAF dissociates from S110/S120 p-SPRY2 IEA Sus scrofa A0A286ZVY2 R-SSC-1295634 https://reactome.org/PathwayBrowser/#/R-SSC-1295634 SPRY2 is serine phosphorylated in response to MAPK activation IEA Sus scrofa A0A286ZVY2 R-SSC-5672950 https://reactome.org/PathwayBrowser/#/R-SSC-5672950 "Activator" RAF:YWHAB dimer binds RAS:GTP IEA Sus scrofa A0A286ZVY2 R-SSC-5672951 https://reactome.org/PathwayBrowser/#/R-SSC-5672951 Inactive RAFs bind YWHAB IEA Sus scrofa A0A286ZVY2 R-SSC-5672960 https://reactome.org/PathwayBrowser/#/R-SSC-5672960 YWHAB dimer dissociates from dephosphorylated RAF IEA Sus scrofa A0A286ZVY2 R-SSC-5672961 https://reactome.org/PathwayBrowser/#/R-SSC-5672961 PP2A dephosphorylates inactive RAFs IEA Sus scrofa A0A286ZVY2 R-SSC-5672966 https://reactome.org/PathwayBrowser/#/R-SSC-5672966 RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers IEA Sus scrofa A0A286ZVY2 R-SSC-5672969 https://reactome.org/PathwayBrowser/#/R-SSC-5672969 Phosphorylation of RAF IEA Sus scrofa A0A286ZVY2 R-SSC-5672972 https://reactome.org/PathwayBrowser/#/R-SSC-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Sus scrofa A0A286ZVY2 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa A0A286ZVY2 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa A0A286ZVY2 R-SSC-5672980 https://reactome.org/PathwayBrowser/#/R-SSC-5672980 Dissociation of RAS:RAF complex IEA Sus scrofa A0A286ZVY2 R-SSC-5674130 https://reactome.org/PathwayBrowser/#/R-SSC-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Sus scrofa A0A286ZVY2 R-SSC-5674132 https://reactome.org/PathwayBrowser/#/R-SSC-5674132 WDR83:LAMTOR2:LAMTOR3 binds MAPK components IEA Sus scrofa A0A286ZVY2 R-SSC-5674140 https://reactome.org/PathwayBrowser/#/R-SSC-5674140 PAQR3 binds inactive RAFs IEA Sus scrofa A0A286ZVY2 R-SSC-5675198 https://reactome.org/PathwayBrowser/#/R-SSC-5675198 Activated MAPKs phosphorylate BRAF IEA Sus scrofa A0A286ZVY2 R-SSC-5675417 https://reactome.org/PathwayBrowser/#/R-SSC-5675417 PEBP1 binds activated RAF1 IEA Sus scrofa A0A286ZVY2 R-SSC-5675431 https://reactome.org/PathwayBrowser/#/R-SSC-5675431 PP2A dephosphorylates RAF1 IEA Sus scrofa A0A286ZVY2 R-SSC-5675433 https://reactome.org/PathwayBrowser/#/R-SSC-5675433 PP5 dephosphorylates RAF1 S338 IEA Sus scrofa A0A286ZVY2 R-SSC-9610152 https://reactome.org/PathwayBrowser/#/R-SSC-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome IEA Sus scrofa A0A286ZVY2 R-SSC-9610153 https://reactome.org/PathwayBrowser/#/R-SSC-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF IEA Sus scrofa A0A286ZVY2 R-SSC-9610154 https://reactome.org/PathwayBrowser/#/R-SSC-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs IEA Sus scrofa A0A286ZVY2 R-SSC-9610156 https://reactome.org/PathwayBrowser/#/R-SSC-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF IEA Sus scrofa A0A286ZVY2 R-SSC-9610163 https://reactome.org/PathwayBrowser/#/R-SSC-9610163 BRAF autophosphorylates downstream of RAP1 and NGF IEA Sus scrofa A0A286ZVY2 R-SSC-9653108 https://reactome.org/PathwayBrowser/#/R-SSC-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Sus scrofa A0A286ZVY2 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa A0A286ZVY2 R-SSC-9657603 https://reactome.org/PathwayBrowser/#/R-SSC-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Sus scrofa A0A286ZVY2 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa A0A286ZVY2 R-SSC-9657608 https://reactome.org/PathwayBrowser/#/R-SSC-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Sus scrofa A0A286ZVY2 R-SSC-9658445 https://reactome.org/PathwayBrowser/#/R-SSC-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Sus scrofa A0A286ZVZ9 R-SSC-3000112 https://reactome.org/PathwayBrowser/#/R-SSC-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Sus scrofa A0A286ZVZ9 R-SSC-3000122 https://reactome.org/PathwayBrowser/#/R-SSC-3000122 CD320 binds extracellular TCN2:RCbl IEA Sus scrofa A0A286ZW00 R-SSC-1296127 https://reactome.org/PathwayBrowser/#/R-SSC-1296127 Activation of voltage gated Potassium channels IEA Sus scrofa A0A286ZW00 R-SSC-5577234 https://reactome.org/PathwayBrowser/#/R-SSC-5577234 KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region IEA Sus scrofa A0A286ZW51 R-SSC-6789310 https://reactome.org/PathwayBrowser/#/R-SSC-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Sus scrofa A0A286ZW56 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZW56 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A286ZW56 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A286ZW56 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A286ZW56 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZW56 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZW56 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A286ZW56 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZW56 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A286ZW63 R-SSC-3928578 https://reactome.org/PathwayBrowser/#/R-SSC-3928578 EPH receptors autophosphorylate IEA Sus scrofa A0A286ZW63 R-SSC-3928591 https://reactome.org/PathwayBrowser/#/R-SSC-3928591 EPH:EFN tetramers oligomerise IEA Sus scrofa A0A286ZW63 R-SSC-3928597 https://reactome.org/PathwayBrowser/#/R-SSC-3928597 EPH:EFN dimers tetramerise IEA Sus scrofa A0A286ZW63 R-SSC-3928604 https://reactome.org/PathwayBrowser/#/R-SSC-3928604 SFKs phosphorylate VAV2,3 IEA Sus scrofa A0A286ZW63 R-SSC-3928607 https://reactome.org/PathwayBrowser/#/R-SSC-3928607 p-EPHs bind VAV2,3 IEA Sus scrofa A0A286ZW63 R-SSC-3928628 https://reactome.org/PathwayBrowser/#/R-SSC-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa A0A286ZW63 R-SSC-3928642 https://reactome.org/PathwayBrowser/#/R-SSC-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa A0A286ZW63 R-SSC-3928646 https://reactome.org/PathwayBrowser/#/R-SSC-3928646 EPHAs bind EFNAs IEA Sus scrofa A0A286ZW63 R-SSC-3928651 https://reactome.org/PathwayBrowser/#/R-SSC-3928651 NGEF exchanges GTP for GDP on RHOA IEA Sus scrofa A0A286ZW63 R-SSC-4093327 https://reactome.org/PathwayBrowser/#/R-SSC-4093327 EPHA binds TIAM1 IEA Sus scrofa A0A286ZW80 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A286ZW80 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A286ZW80 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A286ZW80 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A286ZW80 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A286ZW80 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A286ZW80 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A286ZW80 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A286ZW80 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A286ZW80 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A286ZW80 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A286ZW80 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A286ZW80 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A286ZW80 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A286ZW80 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A286ZW80 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa A0A286ZW80 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa A0A286ZW80 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A286ZW80 R-SSC-983259 https://reactome.org/PathwayBrowser/#/R-SSC-983259 Kinesins move along microtubules consuming ATP IEA Sus scrofa A0A286ZW80 R-SSC-983266 https://reactome.org/PathwayBrowser/#/R-SSC-983266 Kinesins bind microtubules IEA Sus scrofa A0A286ZW80 R-SSC-984689 https://reactome.org/PathwayBrowser/#/R-SSC-984689 Kinesin-7 is a dimer IEA Sus scrofa A0A286ZW91 R-SSC-141423 https://reactome.org/PathwayBrowser/#/R-SSC-141423 Binding of the MCC complex to the APC/C complex IEA Sus scrofa A0A286ZW91 R-SSC-174057 https://reactome.org/PathwayBrowser/#/R-SSC-174057 Multiubiquitination of APC/C-associated Cdh1 IEA Sus scrofa A0A286ZW91 R-SSC-174058 https://reactome.org/PathwayBrowser/#/R-SSC-174058 Degradation of multiubiquitinated Cdh1 IEA Sus scrofa A0A286ZW91 R-SSC-174070 https://reactome.org/PathwayBrowser/#/R-SSC-174070 Association of Cdh1 with the APC/C IEA Sus scrofa A0A286ZW91 R-SSC-174079 https://reactome.org/PathwayBrowser/#/R-SSC-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Sus scrofa A0A286ZW91 R-SSC-174088 https://reactome.org/PathwayBrowser/#/R-SSC-174088 Association of cell cycle proteins with the APC/C:Cdh1 complex IEA Sus scrofa A0A286ZW91 R-SSC-174104 https://reactome.org/PathwayBrowser/#/R-SSC-174104 Ubiquitination of Cyclin A by APC/C:Cdc20 complex IEA Sus scrofa A0A286ZW91 R-SSC-174105 https://reactome.org/PathwayBrowser/#/R-SSC-174105 Degradation of multiubiquitinated cell cycle proteins IEA Sus scrofa A0A286ZW91 R-SSC-174119 https://reactome.org/PathwayBrowser/#/R-SSC-174119 Free APC/C phosphorylated by Plk1 IEA Sus scrofa A0A286ZW91 R-SSC-174120 https://reactome.org/PathwayBrowser/#/R-SSC-174120 Association of Cyclin B:Cdc2 with Cdc20:APC/C complex IEA Sus scrofa A0A286ZW91 R-SSC-174121 https://reactome.org/PathwayBrowser/#/R-SSC-174121 Association of Securin with Cdc20:APC/C complex IEA Sus scrofa A0A286ZW91 R-SSC-174132 https://reactome.org/PathwayBrowser/#/R-SSC-174132 Free APC/C phosphorylated by Cyclin B:Cdc2 IEA Sus scrofa A0A286ZW91 R-SSC-174139 https://reactome.org/PathwayBrowser/#/R-SSC-174139 Dissociation of phospho-Cdh1 from the APC/C complex IEA Sus scrofa A0A286ZW91 R-SSC-174144 https://reactome.org/PathwayBrowser/#/R-SSC-174144 Ubiquitination of Securin by phospho-APC/C:Cdc20 complex IEA Sus scrofa A0A286ZW91 R-SSC-174157 https://reactome.org/PathwayBrowser/#/R-SSC-174157 Degradation of multiubiquitinated Cyclin B IEA Sus scrofa A0A286ZW91 R-SSC-174171 https://reactome.org/PathwayBrowser/#/R-SSC-174171 Association of Cyclin A with the APC/C IEA Sus scrofa A0A286ZW91 R-SSC-174195 https://reactome.org/PathwayBrowser/#/R-SSC-174195 Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex IEA Sus scrofa A0A286ZW91 R-SSC-174202 https://reactome.org/PathwayBrowser/#/R-SSC-174202 Degradation of multiubiquitinated Securin IEA Sus scrofa A0A286ZW91 R-SSC-174224 https://reactome.org/PathwayBrowser/#/R-SSC-174224 Dissociation of Cdc20 from APC/C complex IEA Sus scrofa A0A286ZW91 R-SSC-174227 https://reactome.org/PathwayBrowser/#/R-SSC-174227 Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex IEA Sus scrofa A0A286ZW91 R-SSC-174238 https://reactome.org/PathwayBrowser/#/R-SSC-174238 Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 IEA Sus scrofa A0A286ZW91 R-SSC-174255 https://reactome.org/PathwayBrowser/#/R-SSC-174255 Degradation multiubiquitinated Cyclin A IEA Sus scrofa A0A286ZW91 R-SSC-179417 https://reactome.org/PathwayBrowser/#/R-SSC-179417 Multiubiquitination of Nek2A IEA Sus scrofa A0A286ZW91 R-SSC-179421 https://reactome.org/PathwayBrowser/#/R-SSC-179421 Degradation of multiubiquitinated Nek2A IEA Sus scrofa A0A286ZW91 R-SSC-188191 https://reactome.org/PathwayBrowser/#/R-SSC-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Sus scrofa A0A286ZW91 R-SSC-188371 https://reactome.org/PathwayBrowser/#/R-SSC-188371 Association of Cyclin A:Cdk2 with Cdh1 IEA Sus scrofa A0A286ZW91 R-SSC-3788705 https://reactome.org/PathwayBrowser/#/R-SSC-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Sus scrofa A0A286ZW91 R-SSC-3788708 https://reactome.org/PathwayBrowser/#/R-SSC-3788708 CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 IEA Sus scrofa A0A286ZW91 R-SSC-3788724 https://reactome.org/PathwayBrowser/#/R-SSC-3788724 Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 IEA Sus scrofa A0A286ZW91 R-SSC-3788725 https://reactome.org/PathwayBrowser/#/R-SSC-3788725 Cdh1:APC/C complex binds EHMT1:EHMT2 IEA Sus scrofa A0A286ZW91 R-SSC-68712 https://reactome.org/PathwayBrowser/#/R-SSC-68712 The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 IEA Sus scrofa A0A286ZW91 R-SSC-69015 https://reactome.org/PathwayBrowser/#/R-SSC-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Sus scrofa A0A286ZW91 R-SSC-9686969 https://reactome.org/PathwayBrowser/#/R-SSC-9686969 APC/C:Cdh1 polyubiquitinates SKP2 IEA Sus scrofa A0A286ZW91 R-SSC-9686980 https://reactome.org/PathwayBrowser/#/R-SSC-9686980 RB1 recruits APC/C:Cdh1 complex to SKP2 IEA Sus scrofa A0A286ZW91 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZW91 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A286ZW91 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZW91 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A286ZW94 R-SSC-376419 https://reactome.org/PathwayBrowser/#/R-SSC-376419 Formation of NR-MED1 Coactivator Complex IEA Sus scrofa A0A286ZW94 R-SSC-382096 https://reactome.org/PathwayBrowser/#/R-SSC-382096 Formation of NR-NCOR Corepressor Complex IEA Sus scrofa A0A286ZW95 R-SSC-6814254 https://reactome.org/PathwayBrowser/#/R-SSC-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Sus scrofa A0A286ZW98 R-SSC-176474 https://reactome.org/PathwayBrowser/#/R-SSC-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Sus scrofa A0A286ZW98 R-SSC-176517 https://reactome.org/PathwayBrowser/#/R-SSC-176517 SULTs transfer (SO4)2- group to PREG IEA Sus scrofa A0A286ZW98 R-SSC-176521 https://reactome.org/PathwayBrowser/#/R-SSC-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Sus scrofa A0A286ZW98 R-SSC-176585 https://reactome.org/PathwayBrowser/#/R-SSC-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Sus scrofa A0A286ZW98 R-SSC-176631 https://reactome.org/PathwayBrowser/#/R-SSC-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Sus scrofa A0A286ZW98 R-SSC-176664 https://reactome.org/PathwayBrowser/#/R-SSC-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Sus scrofa A0A286ZW98 R-SSC-9753277 https://reactome.org/PathwayBrowser/#/R-SSC-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Sus scrofa A0A286ZWA5 R-SSC-8866275 https://reactome.org/PathwayBrowser/#/R-SSC-8866275 UBQLNs bind UIM-containing adaptor proteins IEA Sus scrofa A0A286ZWA5 R-SSC-8866283 https://reactome.org/PathwayBrowser/#/R-SSC-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Sus scrofa A0A286ZWC4 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A286ZWE5 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A286ZWE5 R-SSC-517536 https://reactome.org/PathwayBrowser/#/R-SSC-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine IEA Sus scrofa A0A286ZWE5 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A286ZWE5 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A286ZWG1 R-SSC-5654985 https://reactome.org/PathwayBrowser/#/R-SSC-5654985 SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH IEA Sus scrofa A0A286ZWG1 R-SSC-5654989 https://reactome.org/PathwayBrowser/#/R-SSC-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Sus scrofa A0A286ZWG1 R-SSC-9755507 https://reactome.org/PathwayBrowser/#/R-SSC-9755507 UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex IEA Sus scrofa A0A286ZWG1 R-SSC-9758088 https://reactome.org/PathwayBrowser/#/R-SSC-9758088 UBXN7 binds VCP hexamer:UBF1:NPLOC4 IEA Sus scrofa A0A286ZWG1 R-SSC-9758090 https://reactome.org/PathwayBrowser/#/R-SSC-9758090 Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation IEA Sus scrofa A0A286ZWH4 R-SSC-8864278 https://reactome.org/PathwayBrowser/#/R-SSC-8864278 AP-2 (TFAP2) transcription factors form homo- and heterodimers IEA Sus scrofa A0A286ZWH4 R-SSC-8864307 https://reactome.org/PathwayBrowser/#/R-SSC-8864307 TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP IEA Sus scrofa A0A286ZWH4 R-SSC-8864343 https://reactome.org/PathwayBrowser/#/R-SSC-8864343 KCTD1 binds TFAP2 homo- and heterodimers IEA Sus scrofa A0A286ZWH4 R-SSC-9836275 https://reactome.org/PathwayBrowser/#/R-SSC-9836275 TFAP2A binds TFAP2B IEA Sus scrofa A0A286ZWI7 R-SSC-5617815 https://reactome.org/PathwayBrowser/#/R-SSC-5617815 BBSome binds RAB3IP IEA Sus scrofa A0A286ZWI7 R-SSC-5624126 https://reactome.org/PathwayBrowser/#/R-SSC-5624126 ARL6:GTP and the BBSome bind ciliary cargo IEA Sus scrofa A0A286ZWI7 R-SSC-5624127 https://reactome.org/PathwayBrowser/#/R-SSC-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Sus scrofa A0A286ZWI7 R-SSC-5624129 https://reactome.org/PathwayBrowser/#/R-SSC-5624129 LZTFL1 binds the BBSome and prevents its traffic to the cilium IEA Sus scrofa A0A286ZWJ2 R-SSC-9825759 https://reactome.org/PathwayBrowser/#/R-SSC-9825759 MAPK-dependent phosphorylation of KARS IEA Sus scrofa A0A286ZWK2 R-SSC-3371422 https://reactome.org/PathwayBrowser/#/R-SSC-3371422 ATP hydrolysis by HSP70 IEA Sus scrofa A0A286ZWK2 R-SSC-3371467 https://reactome.org/PathwayBrowser/#/R-SSC-3371467 SIRT1 deacetylates HSF1 IEA Sus scrofa A0A286ZWK2 R-SSC-3371503 https://reactome.org/PathwayBrowser/#/R-SSC-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Sus scrofa A0A286ZWK2 R-SSC-3371518 https://reactome.org/PathwayBrowser/#/R-SSC-3371518 SIRT1 binds to HSF1 IEA Sus scrofa A0A286ZWK2 R-SSC-3371554 https://reactome.org/PathwayBrowser/#/R-SSC-3371554 HSF1 acetylation at Lys80 IEA Sus scrofa A0A286ZWK2 R-SSC-3371590 https://reactome.org/PathwayBrowser/#/R-SSC-3371590 HSP70 binds to HSP40:nascent protein IEA Sus scrofa A0A286ZWK2 R-SSC-450551 https://reactome.org/PathwayBrowser/#/R-SSC-450551 AUF1 binds translation and heat shock proteins IEA Sus scrofa A0A286ZWK2 R-SSC-450580 https://reactome.org/PathwayBrowser/#/R-SSC-450580 AUF1 (hnRNP D0) is ubiquitinylated IEA Sus scrofa A0A286ZWK2 R-SSC-5082356 https://reactome.org/PathwayBrowser/#/R-SSC-5082356 HSF1-mediated gene expression IEA Sus scrofa A0A286ZWK2 R-SSC-5082384 https://reactome.org/PathwayBrowser/#/R-SSC-5082384 HSP70:DNAJB1 binds HSF1 IEA Sus scrofa A0A286ZWK2 R-SSC-5251942 https://reactome.org/PathwayBrowser/#/R-SSC-5251942 Hikeshi binds HSP70s:ATP IEA Sus scrofa A0A286ZWK2 R-SSC-5251955 https://reactome.org/PathwayBrowser/#/R-SSC-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Sus scrofa A0A286ZWK2 R-SSC-5251959 https://reactome.org/PathwayBrowser/#/R-SSC-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Sus scrofa A0A286ZWK2 R-SSC-5252041 https://reactome.org/PathwayBrowser/#/R-SSC-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Sus scrofa A0A286ZWK2 R-SSC-5252079 https://reactome.org/PathwayBrowser/#/R-SSC-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Sus scrofa A0A286ZWK2 R-SSC-5618085 https://reactome.org/PathwayBrowser/#/R-SSC-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Sus scrofa A0A286ZWK2 R-SSC-5618098 https://reactome.org/PathwayBrowser/#/R-SSC-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein IEA Sus scrofa A0A286ZWK2 R-SSC-5618105 https://reactome.org/PathwayBrowser/#/R-SSC-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein IEA Sus scrofa A0A286ZWK2 R-SSC-5618107 https://reactome.org/PathwayBrowser/#/R-SSC-5618107 ATP binding to HSP90 triggers conformation change IEA Sus scrofa A0A286ZWK2 R-SSC-5618110 https://reactome.org/PathwayBrowser/#/R-SSC-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein IEA Sus scrofa A0A286ZWK2 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A286ZWK2 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A286ZWK2 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A286ZWK2 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A286ZWK2 R-SSC-888589 https://reactome.org/PathwayBrowser/#/R-SSC-888589 Release of GABA at the synapse IEA Sus scrofa A0A286ZWK2 R-SSC-8932221 https://reactome.org/PathwayBrowser/#/R-SSC-8932221 METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 IEA Sus scrofa A0A286ZWK2 R-SSC-917744 https://reactome.org/PathwayBrowser/#/R-SSC-917744 GABA loaded synaptic vesicle Docking and Priming IEA Sus scrofa A0A286ZWK2 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A286ZWK2 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A286ZWK2 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A286ZWK2 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A286ZWK2 R-SSC-9835411 https://reactome.org/PathwayBrowser/#/R-SSC-9835411 FA core complex:HSP70s binds PKR IEA Sus scrofa A0A286ZWK5 R-SSC-6810233 https://reactome.org/PathwayBrowser/#/R-SSC-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Sus scrofa A0A286ZWK5 R-SSC-6810235 https://reactome.org/PathwayBrowser/#/R-SSC-6810235 RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain IEA Sus scrofa A0A286ZWK5 R-SSC-6810238 https://reactome.org/PathwayBrowser/#/R-SSC-6810238 RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) IEA Sus scrofa A0A286ZWK5 R-SSC-6814549 https://reactome.org/PathwayBrowser/#/R-SSC-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Sus scrofa A0A286ZWK5 R-SSC-6814555 https://reactome.org/PathwayBrowser/#/R-SSC-6814555 Integrator complex processes the 3' end of snRNA IEA Sus scrofa A0A286ZWK5 R-SSC-6814559 https://reactome.org/PathwayBrowser/#/R-SSC-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Sus scrofa A0A286ZWK5 R-SSC-6814885 https://reactome.org/PathwayBrowser/#/R-SSC-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Sus scrofa A0A286ZWK5 R-SSC-83803 https://reactome.org/PathwayBrowser/#/R-SSC-83803 Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex IEA Sus scrofa A0A286ZWL1 R-SSC-445699 https://reactome.org/PathwayBrowser/#/R-SSC-445699 ATP Hydrolysis By Myosin IEA Sus scrofa A0A286ZWL1 R-SSC-445700 https://reactome.org/PathwayBrowser/#/R-SSC-445700 Myosin Binds ATP IEA Sus scrofa A0A286ZWL1 R-SSC-445704 https://reactome.org/PathwayBrowser/#/R-SSC-445704 Calcium Binds Caldesmon IEA Sus scrofa A0A286ZWL1 R-SSC-445705 https://reactome.org/PathwayBrowser/#/R-SSC-445705 Release Of ADP From Myosin IEA Sus scrofa A0A286ZWM0 R-SSC-5694126 https://reactome.org/PathwayBrowser/#/R-SSC-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Sus scrofa A0A286ZWM3 R-SSC-448963 https://reactome.org/PathwayBrowser/#/R-SSC-448963 Interaction of MyoD:E protein with MEF2 IEA Sus scrofa A0A286ZWM3 R-SSC-8956568 https://reactome.org/PathwayBrowser/#/R-SSC-8956568 RUNX1 binds the core TAL1 complex IEA Sus scrofa A0A286ZWM5 R-SSC-8941543 https://reactome.org/PathwayBrowser/#/R-SSC-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region IEA Sus scrofa A0A286ZWN9 R-SSC-5623643 https://reactome.org/PathwayBrowser/#/R-SSC-5623643 RDH13 reduces atRAL to atROL IEA Sus scrofa A0A286ZWQ0 R-SSC-1222376 https://reactome.org/PathwayBrowser/#/R-SSC-1222376 NOX2 generates superoxide from oxygen IEA Sus scrofa A0A286ZWQ0 R-SSC-1236967 https://reactome.org/PathwayBrowser/#/R-SSC-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Sus scrofa A0A286ZWQ0 R-SSC-5218827 https://reactome.org/PathwayBrowser/#/R-SSC-5218827 NADPH oxidase 2 (NOX2) complex binds RAC1 IEA Sus scrofa A0A286ZWQ0 R-SSC-5218841 https://reactome.org/PathwayBrowser/#/R-SSC-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Sus scrofa A0A286ZWQ0 R-SSC-5668605 https://reactome.org/PathwayBrowser/#/R-SSC-5668605 RAC2:GTP binds NOX2 complex IEA Sus scrofa A0A286ZWQ0 R-SSC-5668629 https://reactome.org/PathwayBrowser/#/R-SSC-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Sus scrofa A0A286ZWQ0 R-SSC-5668731 https://reactome.org/PathwayBrowser/#/R-SSC-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa A0A286ZWQ0 R-SSC-5668735 https://reactome.org/PathwayBrowser/#/R-SSC-5668735 RAC1:GTP binds NOX3 complex IEA Sus scrofa A0A286ZWQ0 R-SSC-6789092 https://reactome.org/PathwayBrowser/#/R-SSC-6789092 NOX2 generates superoxide anion from oxygen IEA Sus scrofa A0A286ZWQ0 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZWQ0 R-SSC-9014424 https://reactome.org/PathwayBrowser/#/R-SSC-9014424 RAC2 binds effectors at the phagocytic vesicle membrane IEA Sus scrofa A0A286ZWQ0 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZWQ0 R-SSC-9626816 https://reactome.org/PathwayBrowser/#/R-SSC-9626816 PIN1 binds p-S345-NCF1 IEA Sus scrofa A0A286ZWQ0 R-SSC-9626817 https://reactome.org/PathwayBrowser/#/R-SSC-9626817 PKC phosphorylates NCF1 IEA Sus scrofa A0A286ZWQ0 R-SSC-9626832 https://reactome.org/PathwayBrowser/#/R-SSC-9626832 MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 IEA Sus scrofa A0A286ZWQ0 R-SSC-9626848 https://reactome.org/PathwayBrowser/#/R-SSC-9626848 S100A8:S100A9:AA:Ca(2+) binds NOX2 complex IEA Sus scrofa A0A286ZWQ0 R-SSC-9626880 https://reactome.org/PathwayBrowser/#/R-SSC-9626880 MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 IEA Sus scrofa A0A286ZWQ1 R-SSC-2395320 https://reactome.org/PathwayBrowser/#/R-SSC-2395320 Latent TGF-beta-1 binds integrins IEA Sus scrofa A0A286ZWQ1 R-SSC-2395328 https://reactome.org/PathwayBrowser/#/R-SSC-2395328 LTBP1, LTBP3 bind TGF-Beta IEA Sus scrofa A0A286ZWQ1 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A286ZWQ3 R-SSC-141423 https://reactome.org/PathwayBrowser/#/R-SSC-141423 Binding of the MCC complex to the APC/C complex IEA Sus scrofa A0A286ZWQ3 R-SSC-174057 https://reactome.org/PathwayBrowser/#/R-SSC-174057 Multiubiquitination of APC/C-associated Cdh1 IEA Sus scrofa A0A286ZWQ3 R-SSC-174058 https://reactome.org/PathwayBrowser/#/R-SSC-174058 Degradation of multiubiquitinated Cdh1 IEA Sus scrofa A0A286ZWQ3 R-SSC-174070 https://reactome.org/PathwayBrowser/#/R-SSC-174070 Association of Cdh1 with the APC/C IEA Sus scrofa A0A286ZWQ3 R-SSC-174079 https://reactome.org/PathwayBrowser/#/R-SSC-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Sus scrofa A0A286ZWQ3 R-SSC-174088 https://reactome.org/PathwayBrowser/#/R-SSC-174088 Association of cell cycle proteins with the APC/C:Cdh1 complex IEA Sus scrofa A0A286ZWQ3 R-SSC-174104 https://reactome.org/PathwayBrowser/#/R-SSC-174104 Ubiquitination of Cyclin A by APC/C:Cdc20 complex IEA Sus scrofa A0A286ZWQ3 R-SSC-174105 https://reactome.org/PathwayBrowser/#/R-SSC-174105 Degradation of multiubiquitinated cell cycle proteins IEA Sus scrofa A0A286ZWQ3 R-SSC-174119 https://reactome.org/PathwayBrowser/#/R-SSC-174119 Free APC/C phosphorylated by Plk1 IEA Sus scrofa A0A286ZWQ3 R-SSC-174120 https://reactome.org/PathwayBrowser/#/R-SSC-174120 Association of Cyclin B:Cdc2 with Cdc20:APC/C complex IEA Sus scrofa A0A286ZWQ3 R-SSC-174121 https://reactome.org/PathwayBrowser/#/R-SSC-174121 Association of Securin with Cdc20:APC/C complex IEA Sus scrofa A0A286ZWQ3 R-SSC-174132 https://reactome.org/PathwayBrowser/#/R-SSC-174132 Free APC/C phosphorylated by Cyclin B:Cdc2 IEA Sus scrofa A0A286ZWQ3 R-SSC-174139 https://reactome.org/PathwayBrowser/#/R-SSC-174139 Dissociation of phospho-Cdh1 from the APC/C complex IEA Sus scrofa A0A286ZWQ3 R-SSC-174144 https://reactome.org/PathwayBrowser/#/R-SSC-174144 Ubiquitination of Securin by phospho-APC/C:Cdc20 complex IEA Sus scrofa A0A286ZWQ3 R-SSC-174157 https://reactome.org/PathwayBrowser/#/R-SSC-174157 Degradation of multiubiquitinated Cyclin B IEA Sus scrofa A0A286ZWQ3 R-SSC-174171 https://reactome.org/PathwayBrowser/#/R-SSC-174171 Association of Cyclin A with the APC/C IEA Sus scrofa A0A286ZWQ3 R-SSC-174195 https://reactome.org/PathwayBrowser/#/R-SSC-174195 Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex IEA Sus scrofa A0A286ZWQ3 R-SSC-174202 https://reactome.org/PathwayBrowser/#/R-SSC-174202 Degradation of multiubiquitinated Securin IEA Sus scrofa A0A286ZWQ3 R-SSC-174224 https://reactome.org/PathwayBrowser/#/R-SSC-174224 Dissociation of Cdc20 from APC/C complex IEA Sus scrofa A0A286ZWQ3 R-SSC-174227 https://reactome.org/PathwayBrowser/#/R-SSC-174227 Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex IEA Sus scrofa A0A286ZWQ3 R-SSC-174238 https://reactome.org/PathwayBrowser/#/R-SSC-174238 Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 IEA Sus scrofa A0A286ZWQ3 R-SSC-174255 https://reactome.org/PathwayBrowser/#/R-SSC-174255 Degradation multiubiquitinated Cyclin A IEA Sus scrofa A0A286ZWQ3 R-SSC-179417 https://reactome.org/PathwayBrowser/#/R-SSC-179417 Multiubiquitination of Nek2A IEA Sus scrofa A0A286ZWQ3 R-SSC-179421 https://reactome.org/PathwayBrowser/#/R-SSC-179421 Degradation of multiubiquitinated Nek2A IEA Sus scrofa A0A286ZWQ3 R-SSC-188191 https://reactome.org/PathwayBrowser/#/R-SSC-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Sus scrofa A0A286ZWQ3 R-SSC-188371 https://reactome.org/PathwayBrowser/#/R-SSC-188371 Association of Cyclin A:Cdk2 with Cdh1 IEA Sus scrofa A0A286ZWQ3 R-SSC-3788705 https://reactome.org/PathwayBrowser/#/R-SSC-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Sus scrofa A0A286ZWQ3 R-SSC-3788708 https://reactome.org/PathwayBrowser/#/R-SSC-3788708 CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 IEA Sus scrofa A0A286ZWQ3 R-SSC-3788724 https://reactome.org/PathwayBrowser/#/R-SSC-3788724 Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 IEA Sus scrofa A0A286ZWQ3 R-SSC-3788725 https://reactome.org/PathwayBrowser/#/R-SSC-3788725 Cdh1:APC/C complex binds EHMT1:EHMT2 IEA Sus scrofa A0A286ZWQ3 R-SSC-68712 https://reactome.org/PathwayBrowser/#/R-SSC-68712 The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 IEA Sus scrofa A0A286ZWQ3 R-SSC-69015 https://reactome.org/PathwayBrowser/#/R-SSC-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Sus scrofa A0A286ZWQ3 R-SSC-9686969 https://reactome.org/PathwayBrowser/#/R-SSC-9686969 APC/C:Cdh1 polyubiquitinates SKP2 IEA Sus scrofa A0A286ZWQ3 R-SSC-9686980 https://reactome.org/PathwayBrowser/#/R-SSC-9686980 RB1 recruits APC/C:Cdh1 complex to SKP2 IEA Sus scrofa A0A286ZWQ3 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZWQ3 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A286ZWQ3 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZWQ3 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A286ZWS2 R-SSC-8941234 https://reactome.org/PathwayBrowser/#/R-SSC-8941234 SH3PXD2A binds ADAM12,ADAM15,ADAM19 IEA Sus scrofa A0A286ZWS2 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZWU9 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A286ZWV8 R-SSC-8867876 https://reactome.org/PathwayBrowser/#/R-SSC-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Sus scrofa A0A286ZWW3 R-SSC-5672948 https://reactome.org/PathwayBrowser/#/R-SSC-5672948 MARK3 phosphorylates KSR1 IEA Sus scrofa A0A286ZWW3 R-SSC-5672954 https://reactome.org/PathwayBrowser/#/R-SSC-5672954 p-S311,S406 KSR1:MARK3 binds YWHAB dimer IEA Sus scrofa A0A286ZWW3 R-SSC-5672957 https://reactome.org/PathwayBrowser/#/R-SSC-5672957 PP2A dephosphorylates KSR1 IEA Sus scrofa A0A286ZWW3 R-SSC-5672958 https://reactome.org/PathwayBrowser/#/R-SSC-5672958 YWHAB dimer dissociates from KSR1:MARK3 IEA Sus scrofa A0A286ZWW3 R-SSC-5672966 https://reactome.org/PathwayBrowser/#/R-SSC-5672966 RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers IEA Sus scrofa A0A286ZWW3 R-SSC-5672969 https://reactome.org/PathwayBrowser/#/R-SSC-5672969 Phosphorylation of RAF IEA Sus scrofa A0A286ZWW3 R-SSC-5672972 https://reactome.org/PathwayBrowser/#/R-SSC-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Sus scrofa A0A286ZWW3 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa A0A286ZWW3 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa A0A286ZWW3 R-SSC-5672980 https://reactome.org/PathwayBrowser/#/R-SSC-5672980 Dissociation of RAS:RAF complex IEA Sus scrofa A0A286ZWW3 R-SSC-5674019 https://reactome.org/PathwayBrowser/#/R-SSC-5674019 BRAP binds KSR1:MARK3 IEA Sus scrofa A0A286ZWW3 R-SSC-9653108 https://reactome.org/PathwayBrowser/#/R-SSC-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Sus scrofa A0A286ZWW3 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa A0A286ZWW3 R-SSC-9657603 https://reactome.org/PathwayBrowser/#/R-SSC-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Sus scrofa A0A286ZWW3 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa A0A286ZWW3 R-SSC-9657608 https://reactome.org/PathwayBrowser/#/R-SSC-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Sus scrofa A0A286ZWW3 R-SSC-9926483 https://reactome.org/PathwayBrowser/#/R-SSC-9926483 MARK3 phosphorylates MITF-M on S173 IEA Sus scrofa A0A286ZWW6 R-SSC-9933236 https://reactome.org/PathwayBrowser/#/R-SSC-9933236 SS18-containing ATPase complex binds SMARCC dimer:SMARCDs:BICRAs:BRD9 IEA Sus scrofa A0A286ZWW6 R-SSC-9933237 https://reactome.org/PathwayBrowser/#/R-SSC-9933237 PBRM1-containing ATPase complex binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD&:PHF10 IEA Sus scrofa A0A286ZWW6 R-SSC-9933238 https://reactome.org/PathwayBrowser/#/R-SSC-9933238 SS18-containing ATPase complex binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1:DPF1,2,3 IEA Sus scrofa A0A286ZWW6 R-SSC-9934024 https://reactome.org/PathwayBrowser/#/R-SSC-9934024 SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10 IEA Sus scrofa A0A286ZWX2 R-SSC-418553 https://reactome.org/PathwayBrowser/#/R-SSC-418553 cAMP degradation by Phosphodiesterases IEA Sus scrofa A0A286ZWY1 R-SSC-162425 https://reactome.org/PathwayBrowser/#/R-SSC-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Sus scrofa A0A286ZWY1 R-SSC-9705507 https://reactome.org/PathwayBrowser/#/R-SSC-9705507 PDE3B hydrolyses cAMP to AMP IEA Sus scrofa A0A286ZWY3 R-SSC-1482856 https://reactome.org/PathwayBrowser/#/R-SSC-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Sus scrofa A0A286ZWY3 R-SSC-1482884 https://reactome.org/PathwayBrowser/#/R-SSC-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Sus scrofa A0A286ZWY3 R-SSC-2029475 https://reactome.org/PathwayBrowser/#/R-SSC-2029475 Production of AA by iPLA2 upon FCGR activation IEA Sus scrofa A0A286ZWY3 R-SSC-8848484 https://reactome.org/PathwayBrowser/#/R-SSC-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Sus scrofa A0A286ZWZ7 R-SSC-191763 https://reactome.org/PathwayBrowser/#/R-SSC-191763 snRNP:Snurportin complex formation IEA Sus scrofa A0A286ZWZ7 R-SSC-191784 https://reactome.org/PathwayBrowser/#/R-SSC-191784 snRNA Cap hypermethylation IEA Sus scrofa A0A286ZWZ7 R-SSC-191790 https://reactome.org/PathwayBrowser/#/R-SSC-191790 Loading and methylation of Sm proteins onto SMN Complexes IEA Sus scrofa A0A286ZWZ7 R-SSC-191830 https://reactome.org/PathwayBrowser/#/R-SSC-191830 snRNP nuclear import and release IEA Sus scrofa A0A286ZWZ8 R-SSC-376419 https://reactome.org/PathwayBrowser/#/R-SSC-376419 Formation of NR-MED1 Coactivator Complex IEA Sus scrofa A0A286ZWZ8 R-SSC-382096 https://reactome.org/PathwayBrowser/#/R-SSC-382096 Formation of NR-NCOR Corepressor Complex IEA Sus scrofa A0A286ZX01 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A286ZX01 R-SSC-388468 https://reactome.org/PathwayBrowser/#/R-SSC-388468 AVP(20-28) binds AVPR1A,B IEA Sus scrofa A0A286ZX01 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A286ZX01 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A286ZX01 R-SSC-9667456 https://reactome.org/PathwayBrowser/#/R-SSC-9667456 AVPR1A,B bind desmopressin IEA Sus scrofa A0A286ZX01 R-SSC-9667569 https://reactome.org/PathwayBrowser/#/R-SSC-9667569 AVPR1A,2 bind AVPR antagonists IEA Sus scrofa A0A286ZX01 R-SSC-9667619 https://reactome.org/PathwayBrowser/#/R-SSC-9667619 AVPR1A,B,2 bind atosiban IEA Sus scrofa A0A286ZX16 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A286ZX16 R-SSC-5336184 https://reactome.org/PathwayBrowser/#/R-SSC-5336184 GPR37L binds prosaposin IEA Sus scrofa A0A286ZX16 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A286ZX16 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A286ZX26 R-SSC-2022403 https://reactome.org/PathwayBrowser/#/R-SSC-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Sus scrofa A0A286ZX26 R-SSC-2022412 https://reactome.org/PathwayBrowser/#/R-SSC-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Sus scrofa A0A286ZX26 R-SSC-2130349 https://reactome.org/PathwayBrowser/#/R-SSC-2130349 Generation of CLIP from lip10 IEA Sus scrofa A0A286ZX26 R-SSC-2130504 https://reactome.org/PathwayBrowser/#/R-SSC-2130504 Cleavage of lip22 to lip10 IEA Sus scrofa A0A286ZX26 R-SSC-2130706 https://reactome.org/PathwayBrowser/#/R-SSC-2130706 MHC class II antigen processing IEA Sus scrofa A0A286ZX26 R-SSC-2471621 https://reactome.org/PathwayBrowser/#/R-SSC-2471621 Endostatin degradation by cathepsins IEA Sus scrofa A0A286ZX26 R-SSC-6798745 https://reactome.org/PathwayBrowser/#/R-SSC-6798745 Exocytosis of tertiary granule lumen proteins IEA Sus scrofa A0A286ZX26 R-SSC-6798749 https://reactome.org/PathwayBrowser/#/R-SSC-6798749 Exocytosis of specific granule lumen proteins IEA Sus scrofa A0A286ZX26 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A286ZX26 R-SSC-74730 https://reactome.org/PathwayBrowser/#/R-SSC-74730 Insulin degradation IEA Sus scrofa A0A286ZX29 R-SSC-6800426 https://reactome.org/PathwayBrowser/#/R-SSC-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Sus scrofa A0A286ZX54 R-SSC-1602368 https://reactome.org/PathwayBrowser/#/R-SSC-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Sus scrofa A0A286ZX54 R-SSC-1602374 https://reactome.org/PathwayBrowser/#/R-SSC-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Sus scrofa A0A286ZX54 R-SSC-1602377 https://reactome.org/PathwayBrowser/#/R-SSC-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Sus scrofa A0A286ZX54 R-SSC-1602398 https://reactome.org/PathwayBrowser/#/R-SSC-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Sus scrofa A0A286ZX54 R-SSC-1602417 https://reactome.org/PathwayBrowser/#/R-SSC-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Sus scrofa A0A286ZX54 R-SSC-1602446 https://reactome.org/PathwayBrowser/#/R-SSC-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Sus scrofa A0A286ZX57 R-SSC-5693153 https://reactome.org/PathwayBrowser/#/R-SSC-5693153 PPM1K dephosphorylates p-BCKDH IEA Sus scrofa A0A286ZX65 R-SSC-6814549 https://reactome.org/PathwayBrowser/#/R-SSC-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Sus scrofa A0A286ZX65 R-SSC-6814555 https://reactome.org/PathwayBrowser/#/R-SSC-6814555 Integrator complex processes the 3' end of snRNA IEA Sus scrofa A0A286ZX65 R-SSC-6814559 https://reactome.org/PathwayBrowser/#/R-SSC-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Sus scrofa A0A286ZX65 R-SSC-6814885 https://reactome.org/PathwayBrowser/#/R-SSC-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Sus scrofa A0A286ZX74 R-SSC-159101 https://reactome.org/PathwayBrowser/#/R-SSC-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Sus scrofa A0A286ZX74 R-SSC-72103 https://reactome.org/PathwayBrowser/#/R-SSC-72103 Formation of pre-mRNPs IEA Sus scrofa A0A286ZX74 R-SSC-72180 https://reactome.org/PathwayBrowser/#/R-SSC-72180 Cleavage of mRNA at the 3'-end IEA Sus scrofa A0A286ZX74 R-SSC-72185 https://reactome.org/PathwayBrowser/#/R-SSC-72185 mRNA polyadenylation IEA Sus scrofa A0A286ZX74 R-SSC-8849157 https://reactome.org/PathwayBrowser/#/R-SSC-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Sus scrofa A0A286ZX74 R-SSC-9770119 https://reactome.org/PathwayBrowser/#/R-SSC-9770119 Formation of the Spliceosomal E complex IEA Sus scrofa A0A286ZX74 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A286ZX74 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A286ZX74 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A286ZX74 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A286ZX77 R-SSC-3108203 https://reactome.org/PathwayBrowser/#/R-SSC-3108203 PRC1 SUMOylates CTBP1 with SUMO2,3 IEA Sus scrofa A0A286ZX77 R-SSC-3108209 https://reactome.org/PathwayBrowser/#/R-SSC-3108209 PRC1 SUMOylates CTBP1 with SUMO1 IEA Sus scrofa A0A286ZX77 R-SSC-3229089 https://reactome.org/PathwayBrowser/#/R-SSC-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Sus scrofa A0A286ZX77 R-SSC-3229102 https://reactome.org/PathwayBrowser/#/R-SSC-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Sus scrofa A0A286ZX77 R-SSC-3927824 https://reactome.org/PathwayBrowser/#/R-SSC-3927824 PRC1 SUMOylates CASP8AP2 with SUMO1 IEA Sus scrofa A0A286ZX77 R-SSC-4551655 https://reactome.org/PathwayBrowser/#/R-SSC-4551655 CBX4 SUMOylates BMI1 in PRC1 with SUMO1 IEA Sus scrofa A0A286ZX77 R-SSC-4551727 https://reactome.org/PathwayBrowser/#/R-SSC-4551727 CBX4 SUMOylates CBX4 in PRC1 with SUMO1 IEA Sus scrofa A0A286ZX77 R-SSC-4570463 https://reactome.org/PathwayBrowser/#/R-SSC-4570463 CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 IEA Sus scrofa A0A286ZX77 R-SSC-4570499 https://reactome.org/PathwayBrowser/#/R-SSC-4570499 CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 IEA Sus scrofa A0A286ZX77 R-SSC-8937989 https://reactome.org/PathwayBrowser/#/R-SSC-8937989 RUNX1 binds PRC1 complexes IEA Sus scrofa A0A286ZX77 R-SSC-8943817 https://reactome.org/PathwayBrowser/#/R-SSC-8943817 MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter IEA Sus scrofa A0A286ZX77 R-SSC-9007283 https://reactome.org/PathwayBrowser/#/R-SSC-9007283 CBX3 and PRC1.6 associate with E2F6.com-1 IEA Sus scrofa A0A286ZX77 R-SSC-9007447 https://reactome.org/PathwayBrowser/#/R-SSC-9007447 E2F6 forms the PRC1L4 complex IEA Sus scrofa A0A286ZX85 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A286ZX94 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A286ZX94 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A286ZX94 R-SSC-419389 https://reactome.org/PathwayBrowser/#/R-SSC-419389 LPA-binding receptors bind LPA IEA Sus scrofa A0A286ZX94 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A286ZX94 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A286ZX94 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A286ZX94 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A286ZXA6 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A286ZXA6 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A286ZXA6 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A286ZXA6 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A286ZXA6 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A286ZXB4 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa A0A286ZXB7 R-SSC-8850326 https://reactome.org/PathwayBrowser/#/R-SSC-8850326 TCR binds self-lipid-based antigen via CD1 IEA Sus scrofa A0A286ZXB7 R-SSC-8850356 https://reactome.org/PathwayBrowser/#/R-SSC-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Sus scrofa A0A286ZXD1 R-SSC-8854604 https://reactome.org/PathwayBrowser/#/R-SSC-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Sus scrofa A0A286ZXD1 R-SSC-8875659 https://reactome.org/PathwayBrowser/#/R-SSC-8875659 RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane IEA Sus scrofa A0A286ZXE4 R-SSC-382560 https://reactome.org/PathwayBrowser/#/R-SSC-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Sus scrofa A0A286ZXF1 R-SSC-481044 https://reactome.org/PathwayBrowser/#/R-SSC-481044 Surface deployment of platelet alpha granule membrane components IEA Sus scrofa A0A286ZXF1 R-SSC-6806831 https://reactome.org/PathwayBrowser/#/R-SSC-6806831 CYB5Rs reduce MetHb to HbA IEA Sus scrofa A0A286ZXF3 R-SSC-192097 https://reactome.org/PathwayBrowser/#/R-SSC-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Sus scrofa A0A286ZXF3 R-SSC-193789 https://reactome.org/PathwayBrowser/#/R-SSC-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Sus scrofa A0A286ZXF3 R-SSC-193816 https://reactome.org/PathwayBrowser/#/R-SSC-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Sus scrofa A0A286ZXH5 R-SSC-451283 https://reactome.org/PathwayBrowser/#/R-SSC-451283 kainate receptor binds glutamate IEA Sus scrofa A0A286ZXH5 R-SSC-451309 https://reactome.org/PathwayBrowser/#/R-SSC-451309 Edited Kainate Receptor binds glutamate IEA Sus scrofa A0A286ZXH5 R-SSC-451310 https://reactome.org/PathwayBrowser/#/R-SSC-451310 Activation of Edited Kainate receptors IEA Sus scrofa A0A286ZXH5 R-SSC-451311 https://reactome.org/PathwayBrowser/#/R-SSC-451311 Activation of Ca-permeable Kainate receptors IEA Sus scrofa A0A286ZXK3 R-SSC-165026 https://reactome.org/PathwayBrowser/#/R-SSC-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Sus scrofa A0A286ZXK3 R-SSC-549297 https://reactome.org/PathwayBrowser/#/R-SSC-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Sus scrofa A0A286ZXK7 R-SSC-917696 https://reactome.org/PathwayBrowser/#/R-SSC-917696 Cargo Sequestration IEA Sus scrofa A0A286ZXK7 R-SSC-917730 https://reactome.org/PathwayBrowser/#/R-SSC-917730 Cargo Recognition And Sorting IEA Sus scrofa A0A286ZXL2 R-SSC-8869241 https://reactome.org/PathwayBrowser/#/R-SSC-8869241 PITPNM1,2,3 exchange PI for PA IEA Sus scrofa A0A286ZXL7 R-SSC-5686685 https://reactome.org/PathwayBrowser/#/R-SSC-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Sus scrofa A0A286ZXL7 R-SSC-5686704 https://reactome.org/PathwayBrowser/#/R-SSC-5686704 Activated ATM phosphorylates DCLRE1C IEA Sus scrofa A0A286ZXL7 R-SSC-5686900 https://reactome.org/PathwayBrowser/#/R-SSC-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Sus scrofa A0A286ZXL7 R-SSC-9821395 https://reactome.org/PathwayBrowser/#/R-SSC-9821395 PAXIP1 binds PAGR1 IEA Sus scrofa A0A286ZXM9 R-SSC-5617815 https://reactome.org/PathwayBrowser/#/R-SSC-5617815 BBSome binds RAB3IP IEA Sus scrofa A0A286ZXM9 R-SSC-5624126 https://reactome.org/PathwayBrowser/#/R-SSC-5624126 ARL6:GTP and the BBSome bind ciliary cargo IEA Sus scrofa A0A286ZXM9 R-SSC-5624127 https://reactome.org/PathwayBrowser/#/R-SSC-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Sus scrofa A0A286ZXM9 R-SSC-5624129 https://reactome.org/PathwayBrowser/#/R-SSC-5624129 LZTFL1 binds the BBSome and prevents its traffic to the cilium IEA Sus scrofa A0A286ZXP1 R-SSC-9639287 https://reactome.org/PathwayBrowser/#/R-SSC-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Sus scrofa A0A286ZXP1 R-SSC-9640195 https://reactome.org/PathwayBrowser/#/R-SSC-9640195 RRAGA,B hydrolyzes GTP IEA Sus scrofa A0A286ZXP1 R-SSC-9640237 https://reactome.org/PathwayBrowser/#/R-SSC-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Sus scrofa A0A286ZXP1 R-SSC-9640254 https://reactome.org/PathwayBrowser/#/R-SSC-9640254 BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 IEA Sus scrofa A0A286ZXP1 R-SSC-9657619 https://reactome.org/PathwayBrowser/#/R-SSC-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 IEA Sus scrofa A0A286ZXR4 R-SSC-176956 https://reactome.org/PathwayBrowser/#/R-SSC-176956 Formation of GINS complex IEA Sus scrofa A0A286ZXS0 R-SSC-202967 https://reactome.org/PathwayBrowser/#/R-SSC-202967 Caspase mediated cleavage of alpha-II-Fodrin IEA Sus scrofa A0A286ZXS0 R-SSC-392054 https://reactome.org/PathwayBrowser/#/R-SSC-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Sus scrofa A0A286ZXS0 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A286ZXS0 R-SSC-6798745 https://reactome.org/PathwayBrowser/#/R-SSC-6798745 Exocytosis of tertiary granule lumen proteins IEA Sus scrofa A0A286ZXS0 R-SSC-6798749 https://reactome.org/PathwayBrowser/#/R-SSC-6798749 Exocytosis of specific granule lumen proteins IEA Sus scrofa A0A286ZXS0 R-SSC-6807875 https://reactome.org/PathwayBrowser/#/R-SSC-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Sus scrofa A0A286ZXS0 R-SSC-6807877 https://reactome.org/PathwayBrowser/#/R-SSC-6807877 ARFGAPs stimulate ARF GTPase activity IEA Sus scrofa A0A286ZXS0 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa A0A286ZXS0 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A286ZXS0 R-SSC-6809011 https://reactome.org/PathwayBrowser/#/R-SSC-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Sus scrofa A0A286ZXS0 R-SSC-9018766 https://reactome.org/PathwayBrowser/#/R-SSC-9018766 RHOU binds effectors at the plasma membrane IEA Sus scrofa A0A286ZXS0 R-SSC-9018794 https://reactome.org/PathwayBrowser/#/R-SSC-9018794 RHOV binds effectors at the plasma membrane IEA Sus scrofa A0A286ZXS3 R-SSC-8956568 https://reactome.org/PathwayBrowser/#/R-SSC-8956568 RUNX1 binds the core TAL1 complex IEA Sus scrofa A0A286ZXT3 R-SSC-1675813 https://reactome.org/PathwayBrowser/#/R-SSC-1675813 PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane IEA Sus scrofa A0A286ZXT3 R-SSC-1676185 https://reactome.org/PathwayBrowser/#/R-SSC-1676185 PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane IEA Sus scrofa A0A286ZXT6 R-SSC-6787757 https://reactome.org/PathwayBrowser/#/R-SSC-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Sus scrofa A0A286ZXT6 R-SSC-6814165 https://reactome.org/PathwayBrowser/#/R-SSC-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Sus scrofa A0A286ZXW0 R-SSC-6785126 https://reactome.org/PathwayBrowser/#/R-SSC-6785126 FA core complex assembles at DNA interstrand crosslinks (ICLs) IEA Sus scrofa A0A286ZXW0 R-SSC-6785342 https://reactome.org/PathwayBrowser/#/R-SSC-6785342 FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex IEA Sus scrofa A0A286ZXW0 R-SSC-6785361 https://reactome.org/PathwayBrowser/#/R-SSC-6785361 Monoubiquitination of FANCD2:FANCI IEA Sus scrofa A0A286ZXW0 R-SSC-6785732 https://reactome.org/PathwayBrowser/#/R-SSC-6785732 DNA nucleases bind monoubiquitinated ID2 complex IEA Sus scrofa A0A286ZXW0 R-SSC-6785986 https://reactome.org/PathwayBrowser/#/R-SSC-6785986 DNA nucleases unhook the interstrand crosslink (ICL) IEA Sus scrofa A0A286ZXW0 R-SSC-6786155 https://reactome.org/PathwayBrowser/#/R-SSC-6786155 POLN binds ICL-DNA IEA Sus scrofa A0A286ZXW0 R-SSC-6786166 https://reactome.org/PathwayBrowser/#/R-SSC-6786166 Translesion synthesis across unhooked ICL by POLN IEA Sus scrofa A0A286ZXW0 R-SSC-6786171 https://reactome.org/PathwayBrowser/#/R-SSC-6786171 FANCD2 deubiquitination by USP1:WDR48 IEA Sus scrofa A0A286ZXW0 R-SSC-6788385 https://reactome.org/PathwayBrowser/#/R-SSC-6788385 The complex of ATR and ATRIP is recruited to ICL-DNA IEA Sus scrofa A0A286ZXW0 R-SSC-6788392 https://reactome.org/PathwayBrowser/#/R-SSC-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Sus scrofa A0A286ZXW0 R-SSC-9835411 https://reactome.org/PathwayBrowser/#/R-SSC-9835411 FA core complex:HSP70s binds PKR IEA Sus scrofa A0A286ZXX0 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A286ZXX0 R-SSC-444848 https://reactome.org/PathwayBrowser/#/R-SSC-444848 Relaxin 3 receptor 1 binds relaxin 3 IEA Sus scrofa A0A286ZXX0 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A286ZXX0 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A286ZXX3 R-SSC-1861595 https://reactome.org/PathwayBrowser/#/R-SSC-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Sus scrofa A0A286ZXX3 R-SSC-2029466 https://reactome.org/PathwayBrowser/#/R-SSC-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Sus scrofa A0A286ZXX3 R-SSC-2029473 https://reactome.org/PathwayBrowser/#/R-SSC-2029473 Branching and elongation of mother and daughter filaments IEA Sus scrofa A0A286ZXX3 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A286ZXX3 R-SSC-2197690 https://reactome.org/PathwayBrowser/#/R-SSC-2197690 Detachment of WASP/WAVE IEA Sus scrofa A0A286ZXX3 R-SSC-3928595 https://reactome.org/PathwayBrowser/#/R-SSC-3928595 N-WASP binds ARP2/3 and G-actin IEA Sus scrofa A0A286ZXX3 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A286ZXX3 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A286ZXX3 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A286ZXX3 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A286ZXX3 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A286ZXX3 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A286ZXX3 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A286ZXX3 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A286ZXX3 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A286ZXX3 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A286ZXX3 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A286ZXX3 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A286ZXX4 R-SSC-9907919 https://reactome.org/PathwayBrowser/#/R-SSC-9907919 Formation of the preholoproteasome IEA Sus scrofa A0A286ZXX4 R-SSC-9907940 https://reactome.org/PathwayBrowser/#/R-SSC-9907940 Formation of the preholothymoproteasome IEA Sus scrofa A0A286ZXX4 R-SSC-9907941 https://reactome.org/PathwayBrowser/#/R-SSC-9907941 Fromation of the preholoimmunoproteasome IEA Sus scrofa A0A286ZXX4 R-SSC-9908051 https://reactome.org/PathwayBrowser/#/R-SSC-9908051 PSMG1 binds PSMG2 IEA Sus scrofa A0A286ZXX4 R-SSC-9908052 https://reactome.org/PathwayBrowser/#/R-SSC-9908052 PSMG1:PSMG2 dimer binds the 20S core particle outer ring IEA Sus scrofa A0A286ZXX4 R-SSC-9908069 https://reactome.org/PathwayBrowser/#/R-SSC-9908069 POMP binds the 20S core particle outer ring IEA Sus scrofa A0A286ZXX5 R-SSC-6814121 https://reactome.org/PathwayBrowser/#/R-SSC-6814121 PDCL binds G-protein beta and TRiC/CCT IEA Sus scrofa A0A286ZXX5 R-SSC-6814409 https://reactome.org/PathwayBrowser/#/R-SSC-6814409 CK2 phosphorylates PDCL IEA Sus scrofa A0A286ZXX5 R-SSC-6814418 https://reactome.org/PathwayBrowser/#/R-SSC-6814418 PDCL promotes formation of G-beta:G-gamma heterodimers IEA Sus scrofa A0A286ZXX5 R-SSC-8850527 https://reactome.org/PathwayBrowser/#/R-SSC-8850527 PDCL releases folded G-beta from TRiC/CCT IEA Sus scrofa A0A286ZXX5 R-SSC-8850534 https://reactome.org/PathwayBrowser/#/R-SSC-8850534 PDCL promotes G-protein beta 5 folding IEA Sus scrofa A0A286ZXX5 R-SSC-8850560 https://reactome.org/PathwayBrowser/#/R-SSC-8850560 G-protein alpha releases G-protein heterotrimer from PDCL IEA Sus scrofa A0A286ZXX9 R-SSC-5686475 https://reactome.org/PathwayBrowser/#/R-SSC-5686475 SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2) IEA Sus scrofa A0A286ZXX9 R-SSC-5693584 https://reactome.org/PathwayBrowser/#/R-SSC-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Sus scrofa A0A286ZXX9 R-SSC-6785732 https://reactome.org/PathwayBrowser/#/R-SSC-6785732 DNA nucleases bind monoubiquitinated ID2 complex IEA Sus scrofa A0A286ZXX9 R-SSC-6785986 https://reactome.org/PathwayBrowser/#/R-SSC-6785986 DNA nucleases unhook the interstrand crosslink (ICL) IEA Sus scrofa A0A286ZXZ3 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A286ZXZ3 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A286ZXZ3 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A286ZXZ3 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A286ZY04 R-SSC-6798258 https://reactome.org/PathwayBrowser/#/R-SSC-6798258 PRTPRF, PTPRS, PTPRD bind LRRC4B IEA Sus scrofa A0A286ZY25 R-SSC-5173005 https://reactome.org/PathwayBrowser/#/R-SSC-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Sus scrofa A0A286ZY25 R-SSC-5173192 https://reactome.org/PathwayBrowser/#/R-SSC-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Sus scrofa A0A286ZY48 R-SSC-182986 https://reactome.org/PathwayBrowser/#/R-SSC-182986 CBL-mediated ubiquitination of CIN85 IEA Sus scrofa A0A286ZY48 R-SSC-182990 https://reactome.org/PathwayBrowser/#/R-SSC-182990 Sprouty sequesters CBL away from active EGFR IEA Sus scrofa A0A286ZY48 R-SSC-183072 https://reactome.org/PathwayBrowser/#/R-SSC-183072 EGFR non-clathrin mediated endocytosis IEA Sus scrofa A0A286ZY48 R-SSC-8866275 https://reactome.org/PathwayBrowser/#/R-SSC-8866275 UBQLNs bind UIM-containing adaptor proteins IEA Sus scrofa A0A286ZY48 R-SSC-8866279 https://reactome.org/PathwayBrowser/#/R-SSC-8866279 Epsin family proteins bind ubiquitinated cargo IEA Sus scrofa A0A286ZY48 R-SSC-8866283 https://reactome.org/PathwayBrowser/#/R-SSC-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Sus scrofa A0A286ZY48 R-SSC-8867041 https://reactome.org/PathwayBrowser/#/R-SSC-8867041 EGFR phosphorylates EPS15 IEA Sus scrofa A0A286ZY48 R-SSC-8867044 https://reactome.org/PathwayBrowser/#/R-SSC-8867044 EGFR binds EPS15, EPN1, EPS15L1 IEA Sus scrofa A0A286ZY48 R-SSC-8867047 https://reactome.org/PathwayBrowser/#/R-SSC-8867047 PTPN3 dephosphorylates EPS15 IEA Sus scrofa A0A286ZY48 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A286ZY48 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A286ZY48 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A286ZY48 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A286ZY48 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A286ZY48 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A286ZY48 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A286ZY48 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A286ZY48 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A286ZY48 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A286ZY48 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A286ZY48 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A286ZY48 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A286ZY48 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A286ZY62 R-SSC-212352 https://reactome.org/PathwayBrowser/#/R-SSC-212352 Formation of ARC coactivator complex IEA Sus scrofa A0A286ZY62 R-SSC-212380 https://reactome.org/PathwayBrowser/#/R-SSC-212380 Formation of TRAP coactivator complex IEA Sus scrofa A0A286ZY62 R-SSC-212432 https://reactome.org/PathwayBrowser/#/R-SSC-212432 Formation of DRIP coactivator complex IEA Sus scrofa A0A286ZY62 R-SSC-9843120 https://reactome.org/PathwayBrowser/#/R-SSC-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Sus scrofa A0A286ZY63 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A286ZY67 R-SSC-4724284 https://reactome.org/PathwayBrowser/#/R-SSC-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Sus scrofa A0A286ZY67 R-SSC-5661115 https://reactome.org/PathwayBrowser/#/R-SSC-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Sus scrofa A0A286ZY70 R-SSC-190682 https://reactome.org/PathwayBrowser/#/R-SSC-190682 Connexin synthesis (generic) IEA Sus scrofa A0A286ZYA3 R-SSC-448661 https://reactome.org/PathwayBrowser/#/R-SSC-448661 IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 IEA Sus scrofa A0A286ZYA3 R-SSC-8986985 https://reactome.org/PathwayBrowser/#/R-SSC-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Sus scrofa A0A286ZYA3 R-SSC-8987033 https://reactome.org/PathwayBrowser/#/R-SSC-8987033 p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 IEA Sus scrofa A0A286ZYA3 R-SSC-8987040 https://reactome.org/PathwayBrowser/#/R-SSC-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Sus scrofa A0A286ZYA3 R-SSC-8987105 https://reactome.org/PathwayBrowser/#/R-SSC-8987105 IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 IEA Sus scrofa A0A286ZYA3 R-SSC-8987120 https://reactome.org/PathwayBrowser/#/R-SSC-8987120 JAK1 binds IFNLR1 IEA Sus scrofa A0A286ZYA3 R-SSC-8987202 https://reactome.org/PathwayBrowser/#/R-SSC-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Sus scrofa A0A286ZYA3 R-SSC-8987266 https://reactome.org/PathwayBrowser/#/R-SSC-8987266 IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 IEA Sus scrofa A0A286ZYA4 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZYA4 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A286ZYA4 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZYA4 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A286ZYA7 R-SSC-8854051 https://reactome.org/PathwayBrowser/#/R-SSC-8854051 SCF-FBXL18 ubiquitinates FBXL7 IEA Sus scrofa A0A286ZYA7 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZYA7 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A286ZYA7 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A286ZYA7 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A286ZYA7 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZYA7 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZYA7 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A286ZYA7 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZYA7 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A286ZYA9 R-SSC-139855 https://reactome.org/PathwayBrowser/#/R-SSC-139855 P2X1-mediated entry of Ca++ from plasma IEA Sus scrofa A0A286ZYA9 R-SSC-419490 https://reactome.org/PathwayBrowser/#/R-SSC-419490 Binding of ATP to P2X receptors IEA Sus scrofa A0A286ZYB0 R-SSC-5696007 https://reactome.org/PathwayBrowser/#/R-SSC-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Sus scrofa A0A286ZYB5 R-SSC-73666 https://reactome.org/PathwayBrowser/#/R-SSC-73666 dUTP + H2O => dUMP + pyrophosphate IEA Sus scrofa A0A286ZYB8 R-SSC-140978 https://reactome.org/PathwayBrowser/#/R-SSC-140978 TRADD:TRAF2:RIP1 binds FADD IEA Sus scrofa A0A286ZYB8 R-SSC-5357776 https://reactome.org/PathwayBrowser/#/R-SSC-5357776 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG IEA Sus scrofa A0A286ZYB8 R-SSC-5357845 https://reactome.org/PathwayBrowser/#/R-SSC-5357845 K63polyUb-RIPK1 is deubiquitinated IEA Sus scrofa A0A286ZYB8 R-SSC-5357860 https://reactome.org/PathwayBrowser/#/R-SSC-5357860 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex IEA Sus scrofa A0A286ZYD4 R-SSC-6797553 https://reactome.org/PathwayBrowser/#/R-SSC-6797553 Protein 4.1 binds CASK IEA Sus scrofa A0A286ZYD4 R-SSC-6797568 https://reactome.org/PathwayBrowser/#/R-SSC-6797568 NRXNs bind CASK:Protein 4.1 IEA Sus scrofa A0A286ZYD7 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZYD7 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZYD7 R-SSC-9018746 https://reactome.org/PathwayBrowser/#/R-SSC-9018746 RHOQ binds effectors at the plasma membrane IEA Sus scrofa A0A286ZYE6 R-SSC-450984 https://reactome.org/PathwayBrowser/#/R-SSC-450984 IDH2 dimer decarboxylates isocitrate IEA Sus scrofa A0A286ZYE6 R-SSC-5688289 https://reactome.org/PathwayBrowser/#/R-SSC-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Sus scrofa A0A286ZYE6 R-SSC-9838035 https://reactome.org/PathwayBrowser/#/R-SSC-9838035 CLPXP binds mitochondrial matrix proteins IEA Sus scrofa A0A286ZYE6 R-SSC-9838289 https://reactome.org/PathwayBrowser/#/R-SSC-9838289 CLPXP degrades mitochondrial matrix proteins IEA Sus scrofa A0A286ZYE6 R-SSC-9854415 https://reactome.org/PathwayBrowser/#/R-SSC-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Sus scrofa A0A286ZYE6 R-SSC-9854463 https://reactome.org/PathwayBrowser/#/R-SSC-9854463 SIRT3 deacetylates AcK-IDH2 dimer IEA Sus scrofa A0A286ZYG3 R-SSC-375138 https://reactome.org/PathwayBrowser/#/R-SSC-375138 CDO binds BOC IEA Sus scrofa A0A286ZYG3 R-SSC-375140 https://reactome.org/PathwayBrowser/#/R-SSC-375140 CDO binds promyogenic cadherins IEA Sus scrofa A0A286ZYG3 R-SSC-448958 https://reactome.org/PathwayBrowser/#/R-SSC-448958 Nuclear translocation of p38 MAPK IEA Sus scrofa A0A286ZYG3 R-SSC-5632668 https://reactome.org/PathwayBrowser/#/R-SSC-5632668 SMO translocates to the cilium IEA Sus scrofa A0A286ZYG6 R-SSC-5696358 https://reactome.org/PathwayBrowser/#/R-SSC-5696358 TREM,CD300 binds lipids IEA Sus scrofa A0A286ZYG9 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A286ZYG9 R-SSC-9842833 https://reactome.org/PathwayBrowser/#/R-SSC-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Sus scrofa A0A286ZYH0 R-SSC-5685607 https://reactome.org/PathwayBrowser/#/R-SSC-5685607 Sialic acid binds SIGLEC IEA Sus scrofa A0A286ZYH4 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A286ZYI7 R-SSC-9645598 https://reactome.org/PathwayBrowser/#/R-SSC-9645598 RRAGC,D hydrolyzes GTP IEA Sus scrofa A0A286ZYJ3 R-SSC-8849032 https://reactome.org/PathwayBrowser/#/R-SSC-8849032 PTK6 phosphorylates KHDRBS2 IEA Sus scrofa A0A286ZYJ8 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A286ZYJ8 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A286ZYJ8 R-SSC-927830 https://reactome.org/PathwayBrowser/#/R-SSC-927830 Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex IEA Sus scrofa A0A286ZYJ8 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A286ZYJ8 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A286ZYJ8 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A286ZYM2 R-SSC-8949649 https://reactome.org/PathwayBrowser/#/R-SSC-8949649 PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) IEA Sus scrofa A0A286ZYM2 R-SSC-8949659 https://reactome.org/PathwayBrowser/#/R-SSC-8949659 AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU IEA Sus scrofa A0A286ZYM2 R-SSC-8949661 https://reactome.org/PathwayBrowser/#/R-SSC-8949661 C2orf47:AFG3L2 binds the transit peptide of SMDT1 IEA Sus scrofa A0A286ZYM6 R-SSC-164832 https://reactome.org/PathwayBrowser/#/R-SSC-164832 ATPase synthesizes ATP IEA Sus scrofa A0A286ZYM6 R-SSC-164834 https://reactome.org/PathwayBrowser/#/R-SSC-164834 Enzyme-bound ATP is released IEA Sus scrofa A0A286ZYM6 R-SSC-164840 https://reactome.org/PathwayBrowser/#/R-SSC-164840 ADP and Pi bind to ATPase IEA Sus scrofa A0A286ZYM6 R-SSC-8949580 https://reactome.org/PathwayBrowser/#/R-SSC-8949580 F1Fo ATP synthase dimerizes IEA Sus scrofa A0A286ZYM7 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZYM7 R-SSC-8952626 https://reactome.org/PathwayBrowser/#/R-SSC-8952626 AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZYM7 R-SSC-8952631 https://reactome.org/PathwayBrowser/#/R-SSC-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZYM7 R-SSC-8952638 https://reactome.org/PathwayBrowser/#/R-SSC-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZYM7 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A286ZYM7 R-SSC-8956045 https://reactome.org/PathwayBrowser/#/R-SSC-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZYM7 R-SSC-8956099 https://reactome.org/PathwayBrowser/#/R-SSC-8956099 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 IEA Sus scrofa A0A286ZYM7 R-SSC-8956103 https://reactome.org/PathwayBrowser/#/R-SSC-8956103 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha IEA Sus scrofa A0A286ZYM7 R-SSC-8956106 https://reactome.org/PathwayBrowser/#/R-SSC-8956106 VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha IEA Sus scrofa A0A286ZYM7 R-SSC-9755303 https://reactome.org/PathwayBrowser/#/R-SSC-9755303 26S proteasome degrades HIFalpha IEA Sus scrofa A0A286ZYN3 R-SSC-9909510 https://reactome.org/PathwayBrowser/#/R-SSC-9909510 FKBP5 binds CHUK:IKBKB:IKBKG IEA Sus scrofa A0A286ZYN3 R-SSC-9909519 https://reactome.org/PathwayBrowser/#/R-SSC-9909519 IFI44, IFI44L binds FKBP5 IEA Sus scrofa A0A286ZYQ6 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A286ZYR8 R-SSC-212356 https://reactome.org/PathwayBrowser/#/R-SSC-212356 Formation of CSL-NICD coactivator complex IEA Sus scrofa A0A286ZYR8 R-SSC-8878220 https://reactome.org/PathwayBrowser/#/R-SSC-8878220 RUNX3 binds the NOTCH1 coactivator complex IEA Sus scrofa A0A286ZYS4 R-SSC-8847995 https://reactome.org/PathwayBrowser/#/R-SSC-8847995 Activated ERBB2 binds PTK6 (BRK) IEA Sus scrofa A0A286ZYS4 R-SSC-8848005 https://reactome.org/PathwayBrowser/#/R-SSC-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Sus scrofa A0A286ZYS4 R-SSC-8848023 https://reactome.org/PathwayBrowser/#/R-SSC-8848023 Activated PTK6 binds STAP2 IEA Sus scrofa A0A286ZYS4 R-SSC-8848077 https://reactome.org/PathwayBrowser/#/R-SSC-8848077 PTK6 phosphorylates STAP2 IEA Sus scrofa A0A286ZYS4 R-SSC-8848087 https://reactome.org/PathwayBrowser/#/R-SSC-8848087 STAP2 recruits STAT3 to PTK6 IEA Sus scrofa A0A286ZYS4 R-SSC-8848110 https://reactome.org/PathwayBrowser/#/R-SSC-8848110 SOCS3 binds activated PTK6 IEA Sus scrofa A0A286ZYS4 R-SSC-8848124 https://reactome.org/PathwayBrowser/#/R-SSC-8848124 PTK6 phosphorylates STAT3 IEA Sus scrofa A0A286ZYS4 R-SSC-8848414 https://reactome.org/PathwayBrowser/#/R-SSC-8848414 Activated PTK6 binds CDKN1B IEA Sus scrofa A0A286ZYS4 R-SSC-8848436 https://reactome.org/PathwayBrowser/#/R-SSC-8848436 PTK6 phosphorylates CDKN1B IEA Sus scrofa A0A286ZYS4 R-SSC-8848596 https://reactome.org/PathwayBrowser/#/R-SSC-8848596 PTK6 binds PXN IEA Sus scrofa A0A286ZYS4 R-SSC-8848606 https://reactome.org/PathwayBrowser/#/R-SSC-8848606 PTK6 phosphorylates PXN IEA Sus scrofa A0A286ZYS4 R-SSC-8848713 https://reactome.org/PathwayBrowser/#/R-SSC-8848713 PTK6 binds BCAR1 IEA Sus scrofa A0A286ZYS4 R-SSC-8848726 https://reactome.org/PathwayBrowser/#/R-SSC-8848726 PTK6 phosphorylates BCAR1 IEA Sus scrofa A0A286ZYS4 R-SSC-8848774 https://reactome.org/PathwayBrowser/#/R-SSC-8848774 PTK6 binds DOK1 IEA Sus scrofa A0A286ZYS4 R-SSC-8848776 https://reactome.org/PathwayBrowser/#/R-SSC-8848776 PTK6 phosphorylates DOK1 IEA Sus scrofa A0A286ZYS4 R-SSC-8848818 https://reactome.org/PathwayBrowser/#/R-SSC-8848818 PTK6 phosphorylates CBL IEA Sus scrofa A0A286ZYS4 R-SSC-8848864 https://reactome.org/PathwayBrowser/#/R-SSC-8848864 PTK6 binds ARAP1 IEA Sus scrofa A0A286ZYS4 R-SSC-8848873 https://reactome.org/PathwayBrowser/#/R-SSC-8848873 PTK6 phosphorylates ARAP1 IEA Sus scrofa A0A286ZYS4 R-SSC-8848930 https://reactome.org/PathwayBrowser/#/R-SSC-8848930 PTK6 translocates to the nucleus IEA Sus scrofa A0A286ZYS4 R-SSC-8848939 https://reactome.org/PathwayBrowser/#/R-SSC-8848939 PTK6 binds KHDRBS1 IEA Sus scrofa A0A286ZYS4 R-SSC-8848975 https://reactome.org/PathwayBrowser/#/R-SSC-8848975 PTK6 phosphorylates KHDRBS1 IEA Sus scrofa A0A286ZYS4 R-SSC-8849032 https://reactome.org/PathwayBrowser/#/R-SSC-8849032 PTK6 phosphorylates KHDRBS2 IEA Sus scrofa A0A286ZYS4 R-SSC-8849042 https://reactome.org/PathwayBrowser/#/R-SSC-8849042 PTK6 phosphorylates KHDRBS3 IEA Sus scrofa A0A286ZYS4 R-SSC-8849055 https://reactome.org/PathwayBrowser/#/R-SSC-8849055 PTK6 binds ARHGAP35 IEA Sus scrofa A0A286ZYS4 R-SSC-8849068 https://reactome.org/PathwayBrowser/#/R-SSC-8849068 PTK6 phosphorylates ARHGAP35 IEA Sus scrofa A0A286ZYS4 R-SSC-8849102 https://reactome.org/PathwayBrowser/#/R-SSC-8849102 SRMS phosphorylates PTK6 IEA Sus scrofa A0A286ZYS4 R-SSC-8849428 https://reactome.org/PathwayBrowser/#/R-SSC-8849428 PTPN1 binds PTK6 IEA Sus scrofa A0A286ZYS4 R-SSC-8849435 https://reactome.org/PathwayBrowser/#/R-SSC-8849435 PTPN1 dephosphorylates PTK6 IEA Sus scrofa A0A286ZYS4 R-SSC-8849463 https://reactome.org/PathwayBrowser/#/R-SSC-8849463 PTK6 phosphorylates SFPQ IEA Sus scrofa A0A286ZYS4 R-SSC-8857577 https://reactome.org/PathwayBrowser/#/R-SSC-8857577 LINC01139 facilitates PTK6 autophosphorylation IEA Sus scrofa A0A286ZYS4 R-SSC-8857583 https://reactome.org/PathwayBrowser/#/R-SSC-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Sus scrofa A0A286ZYS4 R-SSC-8942607 https://reactome.org/PathwayBrowser/#/R-SSC-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Sus scrofa A0A286ZYS4 R-SSC-9634702 https://reactome.org/PathwayBrowser/#/R-SSC-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Sus scrofa A0A286ZYS9 R-SSC-6794346 https://reactome.org/PathwayBrowser/#/R-SSC-6794346 NRXNs bind NLGNs IEA Sus scrofa A0A286ZYS9 R-SSC-6797554 https://reactome.org/PathwayBrowser/#/R-SSC-6797554 ABP1 binds SHANK proteins IEA Sus scrofa A0A286ZYS9 R-SSC-6797568 https://reactome.org/PathwayBrowser/#/R-SSC-6797568 NRXNs bind CASK:Protein 4.1 IEA Sus scrofa A0A286ZYS9 R-SSC-6797974 https://reactome.org/PathwayBrowser/#/R-SSC-6797974 LRRTMs bind NRXNs IEA Sus scrofa A0A286ZYU0 R-SSC-3299569 https://reactome.org/PathwayBrowser/#/R-SSC-3299569 Beta-catenin displaces TLE:HDAC1 from TCF/LEF IEA Sus scrofa A0A286ZYU0 R-SSC-3322429 https://reactome.org/PathwayBrowser/#/R-SSC-3322429 XIAP monoubiquinates TLE IEA Sus scrofa A0A286ZYU0 R-SSC-3322431 https://reactome.org/PathwayBrowser/#/R-SSC-3322431 XIAP binds TLE IEA Sus scrofa A0A286ZYU0 R-SSC-3322434 https://reactome.org/PathwayBrowser/#/R-SSC-3322434 XIAP dissociates from ub-TLE IEA Sus scrofa A0A286ZYU0 R-SSC-3361751 https://reactome.org/PathwayBrowser/#/R-SSC-3361751 beta-catenin is replaced by repression complexes at the promoter IEA Sus scrofa A0A286ZYU0 R-SSC-4641229 https://reactome.org/PathwayBrowser/#/R-SSC-4641229 TLE oligomerizes IEA Sus scrofa A0A286ZYU0 R-SSC-8944349 https://reactome.org/PathwayBrowser/#/R-SSC-8944349 TLE tetramers bind TCF/LEF at WNT promoters IEA Sus scrofa A0A286ZYU5 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A286ZYU8 R-SSC-6808496 https://reactome.org/PathwayBrowser/#/R-SSC-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa A0A286ZYV7 R-SSC-71670 https://reactome.org/PathwayBrowser/#/R-SSC-71670 PKM dephosphorylates PEP to PYR IEA Sus scrofa A0A286ZYY7 R-SSC-1297338 https://reactome.org/PathwayBrowser/#/R-SSC-1297338 Association of ADAM and B4GALT1 With ZP3 IEA Sus scrofa A0A286ZYY8 R-SSC-5250930 https://reactome.org/PathwayBrowser/#/R-SSC-5250930 B-WICH recruits histone acetyltransferases IEA Sus scrofa A0A286ZYY8 R-SSC-5250938 https://reactome.org/PathwayBrowser/#/R-SSC-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Sus scrofa A0A286ZZ01 R-SSC-2160931 https://reactome.org/PathwayBrowser/#/R-SSC-2160931 Disassembly of tight junctions IEA Sus scrofa A0A286ZZ01 R-SSC-2160932 https://reactome.org/PathwayBrowser/#/R-SSC-2160932 SMURF1 binds phosphorylated PARD6A IEA Sus scrofa A0A286ZZ01 R-SSC-2160935 https://reactome.org/PathwayBrowser/#/R-SSC-2160935 SMURF1 ubiquitinates RHOA IEA Sus scrofa A0A286ZZ01 R-SSC-419981 https://reactome.org/PathwayBrowser/#/R-SSC-419981 Recruitment of PAR-3:PAR-6:aPKC complex to tight junctions IEA Sus scrofa A0A286ZZ01 R-SSC-4608852 https://reactome.org/PathwayBrowser/#/R-SSC-4608852 SMURF1/2 ubiquitinates PRICKLE1 IEA Sus scrofa A0A286ZZ01 R-SSC-4608854 https://reactome.org/PathwayBrowser/#/R-SSC-4608854 SMURF1/2 are recruited to the DVL2:PARD6A complex IEA Sus scrofa A0A286ZZ01 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZZ01 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZZ01 R-SSC-9018766 https://reactome.org/PathwayBrowser/#/R-SSC-9018766 RHOU binds effectors at the plasma membrane IEA Sus scrofa A0A286ZZ01 R-SSC-9018794 https://reactome.org/PathwayBrowser/#/R-SSC-9018794 RHOV binds effectors at the plasma membrane IEA Sus scrofa A0A286ZZ17 R-SSC-5685838 https://reactome.org/PathwayBrowser/#/R-SSC-5685838 CX3 complex binds D-loop structures IEA Sus scrofa A0A286ZZ17 R-SSC-5686440 https://reactome.org/PathwayBrowser/#/R-SSC-5686440 MUS81:EME1,EME2 cleaves D-loop IEA Sus scrofa A0A286ZZ17 R-SSC-5693539 https://reactome.org/PathwayBrowser/#/R-SSC-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Sus scrofa A0A286ZZ17 R-SSC-5693584 https://reactome.org/PathwayBrowser/#/R-SSC-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Sus scrofa A0A286ZZ17 R-SSC-5693593 https://reactome.org/PathwayBrowser/#/R-SSC-5693593 D-loop extension by DNA polymerases IEA Sus scrofa A0A286ZZ17 R-SSC-5693620 https://reactome.org/PathwayBrowser/#/R-SSC-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Sus scrofa A0A286ZZ17 R-SSC-9853389 https://reactome.org/PathwayBrowser/#/R-SSC-9853389 FIGNL1 binds RAD51 IEA Sus scrofa A0A286ZZ49 R-SSC-389639 https://reactome.org/PathwayBrowser/#/R-SSC-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Sus scrofa A0A286ZZ49 R-SSC-9033232 https://reactome.org/PathwayBrowser/#/R-SSC-9033232 PEX7 binds cargo proteins containing PTS2 IEA Sus scrofa A0A286ZZ49 R-SSC-9033514 https://reactome.org/PathwayBrowser/#/R-SSC-9033514 Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A286ZZ71 R-SSC-1483121 https://reactome.org/PathwayBrowser/#/R-SSC-1483121 PA is converted to CDP-DAG by CDS1 IEA Sus scrofa A0A286ZZ76 R-SSC-6803789 https://reactome.org/PathwayBrowser/#/R-SSC-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Sus scrofa A0A286ZZ78 R-SSC-9932443 https://reactome.org/PathwayBrowser/#/R-SSC-9932443 BICRA, BICRAL and BRD9 bind SMARCC dimer:SMARCDs IEA Sus scrofa A0A286ZZ78 R-SSC-9933236 https://reactome.org/PathwayBrowser/#/R-SSC-9933236 SS18-containing ATPase complex binds SMARCC dimer:SMARCDs:BICRAs:BRD9 IEA Sus scrofa A0A286ZZ81 R-SSC-212352 https://reactome.org/PathwayBrowser/#/R-SSC-212352 Formation of ARC coactivator complex IEA Sus scrofa A0A286ZZ81 R-SSC-212380 https://reactome.org/PathwayBrowser/#/R-SSC-212380 Formation of TRAP coactivator complex IEA Sus scrofa A0A286ZZ81 R-SSC-212432 https://reactome.org/PathwayBrowser/#/R-SSC-212432 Formation of DRIP coactivator complex IEA Sus scrofa A0A286ZZ81 R-SSC-9843120 https://reactome.org/PathwayBrowser/#/R-SSC-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Sus scrofa A0A286ZZ87 R-SSC-5334794 https://reactome.org/PathwayBrowser/#/R-SSC-5334794 FABPs bind LCFAs IEA Sus scrofa A0A286ZZ87 R-SSC-5422942 https://reactome.org/PathwayBrowser/#/R-SSC-5422942 RXRA:PPARD binds FABP5:atRA IEA Sus scrofa A0A286ZZ87 R-SSC-5622129 https://reactome.org/PathwayBrowser/#/R-SSC-5622129 FABP5 binds atRA IEA Sus scrofa A0A286ZZ87 R-SSC-5633256 https://reactome.org/PathwayBrowser/#/R-SSC-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Sus scrofa A0A286ZZ87 R-SSC-5634100 https://reactome.org/PathwayBrowser/#/R-SSC-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Sus scrofa A0A286ZZ87 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A286ZZ87 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A286ZZ91 R-SSC-1297338 https://reactome.org/PathwayBrowser/#/R-SSC-1297338 Association of ADAM and B4GALT1 With ZP3 IEA Sus scrofa A0A286ZZ96 R-SSC-1454916 https://reactome.org/PathwayBrowser/#/R-SSC-1454916 The ABCC family mediates organic anion transport IEA Sus scrofa A0A286ZZ96 R-SSC-383190 https://reactome.org/PathwayBrowser/#/R-SSC-383190 HCO3- transport through ion channel IEA Sus scrofa A0A286ZZ96 R-SSC-5627071 https://reactome.org/PathwayBrowser/#/R-SSC-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane IEA Sus scrofa A0A286ZZ96 R-SSC-5627072 https://reactome.org/PathwayBrowser/#/R-SSC-5627072 RHOQ binds GOPC:CFTR IEA Sus scrofa A0A286ZZ96 R-SSC-5627275 https://reactome.org/PathwayBrowser/#/R-SSC-5627275 GOPC promotes translocation of CFTR to lysosomes IEA Sus scrofa A0A286ZZ96 R-SSC-5678863 https://reactome.org/PathwayBrowser/#/R-SSC-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Sus scrofa A0A286ZZ96 R-SSC-6782106 https://reactome.org/PathwayBrowser/#/R-SSC-6782106 USP10 deubiquitinates SNX3, CFTR IEA Sus scrofa A0A286ZZ96 R-SSC-8866277 https://reactome.org/PathwayBrowser/#/R-SSC-8866277 AP-2 directly binds some endocytic cargo IEA Sus scrofa A0A286ZZ96 R-SSC-8866542 https://reactome.org/PathwayBrowser/#/R-SSC-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Sus scrofa A0A286ZZ96 R-SSC-8866546 https://reactome.org/PathwayBrowser/#/R-SSC-8866546 RNF5 and RNF185 ubiquitinate misfolded CFTR IEA Sus scrofa A0A286ZZ96 R-SSC-8866551 https://reactome.org/PathwayBrowser/#/R-SSC-8866551 CFTR binds components of the ERAD machinery for ubiquitination and degradation IEA Sus scrofa A0A286ZZ96 R-SSC-8866553 https://reactome.org/PathwayBrowser/#/R-SSC-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Sus scrofa A0A286ZZ96 R-SSC-8866851 https://reactome.org/PathwayBrowser/#/R-SSC-8866851 CFTR transits to the plasma membrane IEA Sus scrofa A0A286ZZ96 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A286ZZ96 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A286ZZ96 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A286ZZ96 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A286ZZ96 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A286ZZ96 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A286ZZ96 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A286ZZ96 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A286ZZ96 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A286ZZ96 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A286ZZ96 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A286ZZ96 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A286ZZ96 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A286ZZ96 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A286ZZ96 R-SSC-9641111 https://reactome.org/PathwayBrowser/#/R-SSC-9641111 Parkin transfers Ub to misfolded proteins IEA Sus scrofa A0A286ZZ96 R-SSC-9641127 https://reactome.org/PathwayBrowser/#/R-SSC-9641127 Ub:misfolded proteins polymerize to PolyUb:misfolded proteins IEA Sus scrofa A0A286ZZ96 R-SSC-9646348 https://reactome.org/PathwayBrowser/#/R-SSC-9646348 PolyUb-Misfolded Proteins:HDAC6 bind dynein motor IEA Sus scrofa A0A286ZZ96 R-SSC-9646679 https://reactome.org/PathwayBrowser/#/R-SSC-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Sus scrofa A0A286ZZ96 R-SSC-9646685 https://reactome.org/PathwayBrowser/#/R-SSC-9646685 Aggresome dissociates from dynein and microtubule IEA Sus scrofa A0A286ZZ97 R-SSC-74993 https://reactome.org/PathwayBrowser/#/R-SSC-74993 PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box IEA Sus scrofa A0A286ZZ97 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa A0A286ZZ97 R-SSC-9013024 https://reactome.org/PathwayBrowser/#/R-SSC-9013024 RHOB binds effectors at the plasma membrane IEA Sus scrofa A0A286ZZ97 R-SSC-9013110 https://reactome.org/PathwayBrowser/#/R-SSC-9013110 RHOC binds effectors at the plasma membrane IEA Sus scrofa A0A286ZZA8 R-SSC-9013144 https://reactome.org/PathwayBrowser/#/R-SSC-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Sus scrofa A0A286ZZA8 R-SSC-9013161 https://reactome.org/PathwayBrowser/#/R-SSC-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Sus scrofa A0A286ZZA8 R-SSC-9013437 https://reactome.org/PathwayBrowser/#/R-SSC-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Sus scrofa A0A286ZZA8 R-SSC-9014295 https://reactome.org/PathwayBrowser/#/R-SSC-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Sus scrofa A0A286ZZA8 R-SSC-9018745 https://reactome.org/PathwayBrowser/#/R-SSC-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Sus scrofa A0A286ZZA8 R-SSC-9018806 https://reactome.org/PathwayBrowser/#/R-SSC-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Sus scrofa A0A286ZZA9 R-SSC-373714 https://reactome.org/PathwayBrowser/#/R-SSC-373714 Cis-Heterodimerization of nephrin and KIRREL IEA Sus scrofa A0A286ZZA9 R-SSC-373724 https://reactome.org/PathwayBrowser/#/R-SSC-373724 Nephrin binds NCK IEA Sus scrofa A0A286ZZA9 R-SSC-373732 https://reactome.org/PathwayBrowser/#/R-SSC-373732 Nephrin trans-homophilic interaction IEA Sus scrofa A0A286ZZA9 R-SSC-373734 https://reactome.org/PathwayBrowser/#/R-SSC-373734 Nephrin interacts with Podocin IEA Sus scrofa A0A286ZZA9 R-SSC-373747 https://reactome.org/PathwayBrowser/#/R-SSC-373747 Phosphorylation of nephrin by FYN IEA Sus scrofa A0A286ZZA9 R-SSC-451377 https://reactome.org/PathwayBrowser/#/R-SSC-451377 Interaction of IQGAP1 with nephrin IEA Sus scrofa A0A286ZZA9 R-SSC-451757 https://reactome.org/PathwayBrowser/#/R-SSC-451757 Heterodimerization of nephrin and KIRREL2, KIRREL3 IEA Sus scrofa A0A286ZZA9 R-SSC-532603 https://reactome.org/PathwayBrowser/#/R-SSC-532603 Nephrin mediated activation of N-WASP IEA Sus scrofa A0A286ZZA9 R-SSC-8981534 https://reactome.org/PathwayBrowser/#/R-SSC-8981534 Nephrin dimer:KIRREL binds FYN IEA Sus scrofa A0A286ZZC9 R-SSC-70342 https://reactome.org/PathwayBrowser/#/R-SSC-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Sus scrofa A0A286ZZC9 R-SSC-71495 https://reactome.org/PathwayBrowser/#/R-SSC-71495 Aldolase tetramers convert GA3P and DHAP to F1,6PP IEA Sus scrofa A0A286ZZC9 R-SSC-71496 https://reactome.org/PathwayBrowser/#/R-SSC-71496 Aldolase tetramer cleaves F1,6PP IEA Sus scrofa A0A286ZZD3 R-SSC-1483182 https://reactome.org/PathwayBrowser/#/R-SSC-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Sus scrofa A0A286ZZD3 R-SSC-2029471 https://reactome.org/PathwayBrowser/#/R-SSC-2029471 Hydrolysis of PC to PA by PLD IEA Sus scrofa A0A286ZZD3 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A286ZZD3 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A286ZZD3 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa A0A286ZZD3 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZZD3 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A286ZZD3 R-SSC-9014449 https://reactome.org/PathwayBrowser/#/R-SSC-9014449 RHOG binds effectors at the plasma membrane IEA Sus scrofa A0A286ZZE2 R-SSC-201443 https://reactome.org/PathwayBrowser/#/R-SSC-201443 Type II receptor phosphorylates type I receptor IEA Sus scrofa A0A286ZZE2 R-SSC-201453 https://reactome.org/PathwayBrowser/#/R-SSC-201453 Phospho-R-Smad1/5/8 dissociates from the receptor complex IEA Sus scrofa A0A286ZZE2 R-SSC-201457 https://reactome.org/PathwayBrowser/#/R-SSC-201457 BMP2 binds to the receptor complex IEA Sus scrofa A0A286ZZE2 R-SSC-201475 https://reactome.org/PathwayBrowser/#/R-SSC-201475 I-Smad competes with R-Smad1/5/8 for type I receptor IEA Sus scrofa A0A286ZZE2 R-SSC-201476 https://reactome.org/PathwayBrowser/#/R-SSC-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly IEA Sus scrofa A0A286ZZE2 R-SSC-201648 https://reactome.org/PathwayBrowser/#/R-SSC-201648 An anchoring protein, Endofin, recruits R-Smad1/5/8 IEA Sus scrofa A0A286ZZE2 R-SSC-201810 https://reactome.org/PathwayBrowser/#/R-SSC-201810 The ligand trap binds the ligand BMP2, blocking BMP signalling IEA Sus scrofa A0A286ZZE2 R-SSC-201821 https://reactome.org/PathwayBrowser/#/R-SSC-201821 I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated IEA Sus scrofa A0A286ZZE2 R-SSC-2396399 https://reactome.org/PathwayBrowser/#/R-SSC-2396399 Fibrillins bind BMPs IEA Sus scrofa A0A286ZZG3 R-SSC-6785928 https://reactome.org/PathwayBrowser/#/R-SSC-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly IEA Sus scrofa A0A286ZZG4 R-SSC-1475022 https://reactome.org/PathwayBrowser/#/R-SSC-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Sus scrofa A0A286ZZG4 R-SSC-1475026 https://reactome.org/PathwayBrowser/#/R-SSC-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Sus scrofa A0A286ZZG5 R-SSC-6798372 https://reactome.org/PathwayBrowser/#/R-SSC-6798372 ATM phosphorylates DYRK2 IEA Sus scrofa A0A286ZZG5 R-SSC-6798373 https://reactome.org/PathwayBrowser/#/R-SSC-6798373 MDM2 ubiquitinates DYRK2 IEA Sus scrofa A0A286ZZG5 R-SSC-6798374 https://reactome.org/PathwayBrowser/#/R-SSC-6798374 DYRK2 phosphorylates TP53 IEA Sus scrofa A0A286ZZH4 R-SSC-1655842 https://reactome.org/PathwayBrowser/#/R-SSC-1655842 S1P hydrolyzes SREBP1A,1C,2 IEA Sus scrofa A0A286ZZH4 R-SSC-381135 https://reactome.org/PathwayBrowser/#/R-SSC-381135 MBTPS1 (S1P) cleaves ATF6 (ATF6-alpha) IEA Sus scrofa A0A286ZZH4 R-SSC-8874145 https://reactome.org/PathwayBrowser/#/R-SSC-8874145 MBTPS1 (S1P) cleaves ATF6B (ATF6-beta) IEA Sus scrofa A0A286ZZH4 R-SSC-8874204 https://reactome.org/PathwayBrowser/#/R-SSC-8874204 MBTPS1 (S1P) cleaves CREB3 IEA Sus scrofa A0A286ZZH4 R-SSC-8874206 https://reactome.org/PathwayBrowser/#/R-SSC-8874206 MBTPS1 (S1P) cleaves CREB3L3 IEA Sus scrofa A0A286ZZH4 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A286ZZJ6 R-SSC-2187309 https://reactome.org/PathwayBrowser/#/R-SSC-2187309 SMAD2/3:SMAD4 heterotrimer binds SP1 IEA Sus scrofa A0A286ZZJ6 R-SSC-6810233 https://reactome.org/PathwayBrowser/#/R-SSC-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Sus scrofa A0A286ZZJ6 R-SSC-6810235 https://reactome.org/PathwayBrowser/#/R-SSC-6810235 RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain IEA Sus scrofa A0A286ZZJ6 R-SSC-6810238 https://reactome.org/PathwayBrowser/#/R-SSC-6810238 RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) IEA Sus scrofa A0A286ZZJ6 R-SSC-6814549 https://reactome.org/PathwayBrowser/#/R-SSC-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Sus scrofa A0A286ZZJ6 R-SSC-6814555 https://reactome.org/PathwayBrowser/#/R-SSC-6814555 Integrator complex processes the 3' end of snRNA IEA Sus scrofa A0A286ZZJ6 R-SSC-6814559 https://reactome.org/PathwayBrowser/#/R-SSC-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Sus scrofa A0A286ZZJ6 R-SSC-6814885 https://reactome.org/PathwayBrowser/#/R-SSC-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Sus scrofa A0A286ZZJ6 R-SSC-9023840 https://reactome.org/PathwayBrowser/#/R-SSC-9023840 HATs and coactivators are recruited to the CTSD gene IEA Sus scrofa A0A286ZZK1 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A286ZZQ4 R-SSC-426155 https://reactome.org/PathwayBrowser/#/R-SSC-426155 SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region IEA Sus scrofa A0A286ZZR0 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A286ZZR3 R-SSC-1022133 https://reactome.org/PathwayBrowser/#/R-SSC-1022133 ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans IEA Sus scrofa A0A286ZZR3 R-SSC-4084978 https://reactome.org/PathwayBrowser/#/R-SSC-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Sus scrofa A0A286ZZS9 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A286ZZS9 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A286ZZS9 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A286ZZS9 R-SSC-8851298 https://reactome.org/PathwayBrowser/#/R-SSC-8851298 GPR143 binds L-Dopa IEA Sus scrofa A0A286ZZT9 R-SSC-109638 https://reactome.org/PathwayBrowser/#/R-SSC-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Sus scrofa A0A286ZZT9 R-SSC-109639 https://reactome.org/PathwayBrowser/#/R-SSC-109639 Formation of the closed pre-initiation complex IEA Sus scrofa A0A286ZZT9 R-SSC-111264 https://reactome.org/PathwayBrowser/#/R-SSC-111264 Addition of nucleotides between position +11 and +30 IEA Sus scrofa A0A286ZZT9 R-SSC-112379 https://reactome.org/PathwayBrowser/#/R-SSC-112379 Recruitment of elongation factors to form elongation complex IEA Sus scrofa A0A286ZZT9 R-SSC-112381 https://reactome.org/PathwayBrowser/#/R-SSC-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Sus scrofa A0A286ZZT9 R-SSC-112383 https://reactome.org/PathwayBrowser/#/R-SSC-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Sus scrofa A0A286ZZT9 R-SSC-112385 https://reactome.org/PathwayBrowser/#/R-SSC-112385 Addition of nucleotides leads to transcript elongation IEA Sus scrofa A0A286ZZT9 R-SSC-112392 https://reactome.org/PathwayBrowser/#/R-SSC-112392 Resumption of elongation after recovery from pausing IEA Sus scrofa A0A286ZZT9 R-SSC-112395 https://reactome.org/PathwayBrowser/#/R-SSC-112395 Abortive termination of elongation after arrest IEA Sus scrofa A0A286ZZT9 R-SSC-112396 https://reactome.org/PathwayBrowser/#/R-SSC-112396 Separation of elongating transcript from template IEA Sus scrofa A0A286ZZT9 R-SSC-113402 https://reactome.org/PathwayBrowser/#/R-SSC-113402 Formation of DSIF:NELF:early elongation complex IEA Sus scrofa A0A286ZZT9 R-SSC-113407 https://reactome.org/PathwayBrowser/#/R-SSC-113407 DSIF complex binds to RNA Pol II (hypophosphorylated) IEA Sus scrofa A0A286ZZT9 R-SSC-113409 https://reactome.org/PathwayBrowser/#/R-SSC-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Sus scrofa A0A286ZZT9 R-SSC-113411 https://reactome.org/PathwayBrowser/#/R-SSC-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Sus scrofa A0A286ZZT9 R-SSC-113412 https://reactome.org/PathwayBrowser/#/R-SSC-113412 Pol II elongation complex moves on the template as transcript elongates IEA Sus scrofa A0A286ZZT9 R-SSC-113413 https://reactome.org/PathwayBrowser/#/R-SSC-113413 TFIIS-mediated recovery of elongation from arrest IEA Sus scrofa A0A286ZZT9 R-SSC-113414 https://reactome.org/PathwayBrowser/#/R-SSC-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Sus scrofa A0A286ZZT9 R-SSC-113429 https://reactome.org/PathwayBrowser/#/R-SSC-113429 Elongating transcript encounters a lesion in the template IEA Sus scrofa A0A286ZZT9 R-SSC-113430 https://reactome.org/PathwayBrowser/#/R-SSC-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Sus scrofa A0A286ZZT9 R-SSC-6797606 https://reactome.org/PathwayBrowser/#/R-SSC-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Sus scrofa A0A286ZZT9 R-SSC-6797616 https://reactome.org/PathwayBrowser/#/R-SSC-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Sus scrofa A0A286ZZT9 R-SSC-6803523 https://reactome.org/PathwayBrowser/#/R-SSC-6803523 PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA IEA Sus scrofa A0A286ZZT9 R-SSC-6810233 https://reactome.org/PathwayBrowser/#/R-SSC-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Sus scrofa A0A286ZZT9 R-SSC-6810235 https://reactome.org/PathwayBrowser/#/R-SSC-6810235 RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain IEA Sus scrofa A0A286ZZT9 R-SSC-6810238 https://reactome.org/PathwayBrowser/#/R-SSC-6810238 RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) IEA Sus scrofa A0A286ZZT9 R-SSC-6814549 https://reactome.org/PathwayBrowser/#/R-SSC-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Sus scrofa A0A286ZZT9 R-SSC-6814555 https://reactome.org/PathwayBrowser/#/R-SSC-6814555 Integrator complex processes the 3' end of snRNA IEA Sus scrofa A0A286ZZT9 R-SSC-6814559 https://reactome.org/PathwayBrowser/#/R-SSC-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Sus scrofa A0A286ZZT9 R-SSC-6814885 https://reactome.org/PathwayBrowser/#/R-SSC-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Sus scrofa A0A286ZZT9 R-SSC-72095 https://reactome.org/PathwayBrowser/#/R-SSC-72095 Internal Methylation of mRNA IEA Sus scrofa A0A286ZZT9 R-SSC-72103 https://reactome.org/PathwayBrowser/#/R-SSC-72103 Formation of pre-mRNPs IEA Sus scrofa A0A286ZZT9 R-SSC-73946 https://reactome.org/PathwayBrowser/#/R-SSC-73946 Abortive initiation after formation of the first phosphodiester bond IEA Sus scrofa A0A286ZZT9 R-SSC-75079 https://reactome.org/PathwayBrowser/#/R-SSC-75079 Formation of AT-AC C complex IEA Sus scrofa A0A286ZZT9 R-SSC-75081 https://reactome.org/PathwayBrowser/#/R-SSC-75081 Formation of AT-AC B Complex IEA Sus scrofa A0A286ZZT9 R-SSC-75082 https://reactome.org/PathwayBrowser/#/R-SSC-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Sus scrofa A0A286ZZT9 R-SSC-75083 https://reactome.org/PathwayBrowser/#/R-SSC-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Sus scrofa A0A286ZZT9 R-SSC-75095 https://reactome.org/PathwayBrowser/#/R-SSC-75095 Binding of TFIIE to the growing preinitiation complex IEA Sus scrofa A0A286ZZT9 R-SSC-75850 https://reactome.org/PathwayBrowser/#/R-SSC-75850 Addition of the third nucleotide on the nascent transcript IEA Sus scrofa A0A286ZZT9 R-SSC-75856 https://reactome.org/PathwayBrowser/#/R-SSC-75856 Abortive Initiation Before Second Transition IEA Sus scrofa A0A286ZZT9 R-SSC-75861 https://reactome.org/PathwayBrowser/#/R-SSC-75861 NTP Binds Active Site of RNA Polymerase II IEA Sus scrofa A0A286ZZT9 R-SSC-75862 https://reactome.org/PathwayBrowser/#/R-SSC-75862 Fall Back to Closed Pre-initiation Complex IEA Sus scrofa A0A286ZZT9 R-SSC-75864 https://reactome.org/PathwayBrowser/#/R-SSC-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Sus scrofa A0A286ZZT9 R-SSC-75866 https://reactome.org/PathwayBrowser/#/R-SSC-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Sus scrofa A0A286ZZT9 R-SSC-75869 https://reactome.org/PathwayBrowser/#/R-SSC-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Sus scrofa A0A286ZZT9 R-SSC-75873 https://reactome.org/PathwayBrowser/#/R-SSC-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Sus scrofa A0A286ZZT9 R-SSC-75891 https://reactome.org/PathwayBrowser/#/R-SSC-75891 Abortive Initiation After Second Transition IEA Sus scrofa A0A286ZZT9 R-SSC-75949 https://reactome.org/PathwayBrowser/#/R-SSC-75949 RNA Polymerase II Promoter Opening: First Transition IEA Sus scrofa A0A286ZZT9 R-SSC-76576 https://reactome.org/PathwayBrowser/#/R-SSC-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Sus scrofa A0A286ZZT9 R-SSC-77068 https://reactome.org/PathwayBrowser/#/R-SSC-77068 Activation of GT IEA Sus scrofa A0A286ZZT9 R-SSC-77069 https://reactome.org/PathwayBrowser/#/R-SSC-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Sus scrofa A0A286ZZT9 R-SSC-77071 https://reactome.org/PathwayBrowser/#/R-SSC-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Sus scrofa A0A286ZZT9 R-SSC-77073 https://reactome.org/PathwayBrowser/#/R-SSC-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Sus scrofa A0A286ZZT9 R-SSC-77077 https://reactome.org/PathwayBrowser/#/R-SSC-77077 Capping complex formation IEA Sus scrofa A0A286ZZT9 R-SSC-77078 https://reactome.org/PathwayBrowser/#/R-SSC-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Sus scrofa A0A286ZZT9 R-SSC-77081 https://reactome.org/PathwayBrowser/#/R-SSC-77081 Formation of the CE:GMP intermediate complex IEA Sus scrofa A0A286ZZT9 R-SSC-77083 https://reactome.org/PathwayBrowser/#/R-SSC-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Sus scrofa A0A286ZZT9 R-SSC-77085 https://reactome.org/PathwayBrowser/#/R-SSC-77085 Dissociation of transcript with 5'-GMP from GT IEA Sus scrofa A0A286ZZT9 R-SSC-77090 https://reactome.org/PathwayBrowser/#/R-SSC-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Sus scrofa A0A286ZZT9 R-SSC-77095 https://reactome.org/PathwayBrowser/#/R-SSC-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Sus scrofa A0A286ZZT9 R-SSC-9012315 https://reactome.org/PathwayBrowser/#/R-SSC-9012315 ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene IEA Sus scrofa A0A286ZZT9 R-SSC-9012319 https://reactome.org/PathwayBrowser/#/R-SSC-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Sus scrofa A0A286ZZT9 R-SSC-9613494 https://reactome.org/PathwayBrowser/#/R-SSC-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Sus scrofa A0A286ZZT9 R-SSC-9613497 https://reactome.org/PathwayBrowser/#/R-SSC-9613497 Unwinding DNA for the nascent transcript IEA Sus scrofa A0A286ZZT9 R-SSC-9770119 https://reactome.org/PathwayBrowser/#/R-SSC-9770119 Formation of the Spliceosomal E complex IEA Sus scrofa A0A286ZZT9 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A286ZZT9 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A286ZZT9 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A286ZZT9 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A286ZZU1 R-SSC-2997723 https://reactome.org/PathwayBrowser/#/R-SSC-2997723 PIAS4 SUMOylates TP53BP1 with SUMO1 IEA Sus scrofa A0A286ZZU1 R-SSC-5683384 https://reactome.org/PathwayBrowser/#/R-SSC-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Sus scrofa A0A286ZZU1 R-SSC-5683385 https://reactome.org/PathwayBrowser/#/R-SSC-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Sus scrofa A0A286ZZU1 R-SSC-5683405 https://reactome.org/PathwayBrowser/#/R-SSC-5683405 PPP5C dephosphorylates TP53BP1 IEA Sus scrofa A0A286ZZU1 R-SSC-5683425 https://reactome.org/PathwayBrowser/#/R-SSC-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Sus scrofa A0A286ZZU1 R-SSC-5683735 https://reactome.org/PathwayBrowser/#/R-SSC-5683735 CHEK2 is recruited to DNA DSBs IEA Sus scrofa A0A286ZZU1 R-SSC-5683801 https://reactome.org/PathwayBrowser/#/R-SSC-5683801 CHEK2 phosphorylates BRCA1 IEA Sus scrofa A0A286ZZU1 R-SSC-5684052 https://reactome.org/PathwayBrowser/#/R-SSC-5684052 PIAS4 SUMOylates MDC1 IEA Sus scrofa A0A286ZZU1 R-SSC-5686685 https://reactome.org/PathwayBrowser/#/R-SSC-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Sus scrofa A0A286ZZU1 R-SSC-5686704 https://reactome.org/PathwayBrowser/#/R-SSC-5686704 Activated ATM phosphorylates DCLRE1C IEA Sus scrofa A0A286ZZU1 R-SSC-5686900 https://reactome.org/PathwayBrowser/#/R-SSC-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Sus scrofa A0A286ZZU1 R-SSC-5693551 https://reactome.org/PathwayBrowser/#/R-SSC-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Sus scrofa A0A286ZZU1 R-SSC-5693566 https://reactome.org/PathwayBrowser/#/R-SSC-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Sus scrofa A0A286ZZU1 R-SSC-69891 https://reactome.org/PathwayBrowser/#/R-SSC-69891 Phosphorylation and activation of CHEK2 by ATM IEA Sus scrofa A0A286ZZU8 R-SSC-212380 https://reactome.org/PathwayBrowser/#/R-SSC-212380 Formation of TRAP coactivator complex IEA Sus scrofa A0A286ZZU8 R-SSC-9843120 https://reactome.org/PathwayBrowser/#/R-SSC-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Sus scrofa A0A286ZZW3 R-SSC-1226094 https://reactome.org/PathwayBrowser/#/R-SSC-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Sus scrofa A0A286ZZW3 R-SSC-1226095 https://reactome.org/PathwayBrowser/#/R-SSC-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Sus scrofa A0A286ZZW3 R-SSC-1227670 https://reactome.org/PathwayBrowser/#/R-SSC-1227670 Recruitment of HDAC1 by p130 (RBL2) IEA Sus scrofa A0A286ZZW3 R-SSC-1227671 https://reactome.org/PathwayBrowser/#/R-SSC-1227671 Recruitment of HDAC1 by p107 (RBL1) IEA Sus scrofa A0A286ZZW3 R-SSC-1362261 https://reactome.org/PathwayBrowser/#/R-SSC-1362261 p130 (RBL2) associates with MuvB to form DREAM complex IEA Sus scrofa A0A286ZZW3 R-SSC-1363303 https://reactome.org/PathwayBrowser/#/R-SSC-1363303 p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 IEA Sus scrofa A0A286ZZW3 R-SSC-1363311 https://reactome.org/PathwayBrowser/#/R-SSC-1363311 p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 IEA Sus scrofa A0A286ZZW3 R-SSC-2127257 https://reactome.org/PathwayBrowser/#/R-SSC-2127257 SMAD2/3:SMAD4 heterotrimer forms a complex with RBL1, E2F4/5 and DP1/2 IEA Sus scrofa A0A286ZZW5 R-SSC-201639 https://reactome.org/PathwayBrowser/#/R-SSC-201639 Caspase-mediated cleavage of GAS2 IEA Sus scrofa A0A286ZZX3 R-SSC-481009 https://reactome.org/PathwayBrowser/#/R-SSC-481009 Exocytosis of platelet dense granule content IEA Sus scrofa A0A286ZZZ8 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZZZ8 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A286ZZZ8 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZZZ8 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A286ZZZ9 R-SSC-5658424 https://reactome.org/PathwayBrowser/#/R-SSC-5658424 KBTBD7:CUL3:RBX1 ubiquitinates NF1 IEA Sus scrofa A0A286ZZZ9 R-SSC-8952631 https://reactome.org/PathwayBrowser/#/R-SSC-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Sus scrofa A0A286ZZZ9 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A286ZZZ9 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A286ZZZ9 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A286ZZZ9 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A286ZZZ9 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A286ZZZ9 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A286ZZZ9 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287A000 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287A000 R-SSC-182986 https://reactome.org/PathwayBrowser/#/R-SSC-182986 CBL-mediated ubiquitination of CIN85 IEA Sus scrofa A0A287A000 R-SSC-182990 https://reactome.org/PathwayBrowser/#/R-SSC-182990 Sprouty sequesters CBL away from active EGFR IEA Sus scrofa A0A287A000 R-SSC-182994 https://reactome.org/PathwayBrowser/#/R-SSC-182994 Assembly of EGFR complex in clathrin-coated vesicles IEA Sus scrofa A0A287A000 R-SSC-183002 https://reactome.org/PathwayBrowser/#/R-SSC-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Sus scrofa A0A287A000 R-SSC-183072 https://reactome.org/PathwayBrowser/#/R-SSC-183072 EGFR non-clathrin mediated endocytosis IEA Sus scrofa A0A287A000 R-SSC-8855237 https://reactome.org/PathwayBrowser/#/R-SSC-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 IEA Sus scrofa A0A287A000 R-SSC-8855259 https://reactome.org/PathwayBrowser/#/R-SSC-8855259 RELN:VLDLR:DAB1 binds SH3KBP1 IEA Sus scrofa A0A287A000 R-SSC-8866279 https://reactome.org/PathwayBrowser/#/R-SSC-8866279 Epsin family proteins bind ubiquitinated cargo IEA Sus scrofa A0A287A000 R-SSC-8867041 https://reactome.org/PathwayBrowser/#/R-SSC-8867041 EGFR phosphorylates EPS15 IEA Sus scrofa A0A287A000 R-SSC-8867044 https://reactome.org/PathwayBrowser/#/R-SSC-8867044 EGFR binds EPS15, EPN1, EPS15L1 IEA Sus scrofa A0A287A000 R-SSC-8867047 https://reactome.org/PathwayBrowser/#/R-SSC-8867047 PTPN3 dephosphorylates EPS15 IEA Sus scrofa A0A287A000 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A287A000 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A287A000 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A287A000 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A287A000 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A287A000 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287A000 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287A000 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287A000 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287A000 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287A000 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287A000 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287A000 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287A000 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287A000 R-SSC-8875482 https://reactome.org/PathwayBrowser/#/R-SSC-8875482 CBL recruits CIN85:endophilin to ubiquitinated MET IEA Sus scrofa A0A287A000 R-SSC-8875490 https://reactome.org/PathwayBrowser/#/R-SSC-8875490 EPS15 and HGS bind ubiquitinated MET IEA Sus scrofa A0A287A000 R-SSC-8951490 https://reactome.org/PathwayBrowser/#/R-SSC-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Sus scrofa A0A287A000 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287A000 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287A000 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287A004 R-SSC-199112 https://reactome.org/PathwayBrowser/#/R-SSC-199112 CRTAM binds to NECL2 IEA Sus scrofa A0A287A007 R-SSC-1454757 https://reactome.org/PathwayBrowser/#/R-SSC-1454757 Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 IEA Sus scrofa A0A287A007 R-SSC-1564142 https://reactome.org/PathwayBrowser/#/R-SSC-1564142 Collagen type IV degradation by MMP2,3,4,9,10,12 IEA Sus scrofa A0A287A007 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa A0A287A007 R-SSC-1981104 https://reactome.org/PathwayBrowser/#/R-SSC-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Sus scrofa A0A287A007 R-SSC-1981120 https://reactome.org/PathwayBrowser/#/R-SSC-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Sus scrofa A0A287A007 R-SSC-1981128 https://reactome.org/PathwayBrowser/#/R-SSC-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Sus scrofa A0A287A007 R-SSC-1981157 https://reactome.org/PathwayBrowser/#/R-SSC-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Sus scrofa A0A287A007 R-SSC-2002460 https://reactome.org/PathwayBrowser/#/R-SSC-2002460 P4HB binds Collagen chains IEA Sus scrofa A0A287A007 R-SSC-2089971 https://reactome.org/PathwayBrowser/#/R-SSC-2089971 Secretion of collagens IEA Sus scrofa A0A287A007 R-SSC-2213207 https://reactome.org/PathwayBrowser/#/R-SSC-2213207 Formation of collagen networks IEA Sus scrofa A0A287A007 R-SSC-2327695 https://reactome.org/PathwayBrowser/#/R-SSC-2327695 Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 IEA Sus scrofa A0A287A007 R-SSC-2327733 https://reactome.org/PathwayBrowser/#/R-SSC-2327733 FN1 binds Collagen types I-V, VII IEA Sus scrofa A0A287A007 R-SSC-2327738 https://reactome.org/PathwayBrowser/#/R-SSC-2327738 DDR1 binds collagen type I, II, III, IV, V, XI fibrils IEA Sus scrofa A0A287A007 R-SSC-2426450 https://reactome.org/PathwayBrowser/#/R-SSC-2426450 Laminins:Nidogens binds collagen type IV networks IEA Sus scrofa A0A287A007 R-SSC-2559639 https://reactome.org/PathwayBrowser/#/R-SSC-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Sus scrofa A0A287A007 R-SSC-382054 https://reactome.org/PathwayBrowser/#/R-SSC-382054 PDGF binds to extracellular matrix proteins IEA Sus scrofa A0A287A007 R-SSC-8944265 https://reactome.org/PathwayBrowser/#/R-SSC-8944265 Association of procollagen type IV IEA Sus scrofa A0A287A007 R-SSC-8948219 https://reactome.org/PathwayBrowser/#/R-SSC-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A287A007 R-SSC-8948222 https://reactome.org/PathwayBrowser/#/R-SSC-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287A007 R-SSC-8948224 https://reactome.org/PathwayBrowser/#/R-SSC-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287A007 R-SSC-8948228 https://reactome.org/PathwayBrowser/#/R-SSC-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A287A007 R-SSC-8948231 https://reactome.org/PathwayBrowser/#/R-SSC-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287A007 R-SSC-8948232 https://reactome.org/PathwayBrowser/#/R-SSC-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Sus scrofa A0A287A007 R-SSC-8948234 https://reactome.org/PathwayBrowser/#/R-SSC-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Sus scrofa A0A287A009 R-SSC-3928578 https://reactome.org/PathwayBrowser/#/R-SSC-3928578 EPH receptors autophosphorylate IEA Sus scrofa A0A287A009 R-SSC-3928591 https://reactome.org/PathwayBrowser/#/R-SSC-3928591 EPH:EFN tetramers oligomerise IEA Sus scrofa A0A287A009 R-SSC-3928592 https://reactome.org/PathwayBrowser/#/R-SSC-3928592 p190RhoGEF exchanges GTP for GDP on RHOA, activating it IEA Sus scrofa A0A287A009 R-SSC-3928595 https://reactome.org/PathwayBrowser/#/R-SSC-3928595 N-WASP binds ARP2/3 and G-actin IEA Sus scrofa A0A287A009 R-SSC-3928597 https://reactome.org/PathwayBrowser/#/R-SSC-3928597 EPH:EFN dimers tetramerise IEA Sus scrofa A0A287A009 R-SSC-3928601 https://reactome.org/PathwayBrowser/#/R-SSC-3928601 CDC42 and PIP2 bind WASL, activating it IEA Sus scrofa A0A287A009 R-SSC-3928604 https://reactome.org/PathwayBrowser/#/R-SSC-3928604 SFKs phosphorylate VAV2,3 IEA Sus scrofa A0A287A009 R-SSC-3928607 https://reactome.org/PathwayBrowser/#/R-SSC-3928607 p-EPHs bind VAV2,3 IEA Sus scrofa A0A287A009 R-SSC-3928614 https://reactome.org/PathwayBrowser/#/R-SSC-3928614 EFNB:GRB4 binds GIT1 IEA Sus scrofa A0A287A009 R-SSC-3928615 https://reactome.org/PathwayBrowser/#/R-SSC-3928615 EFNBs bind SFKs IEA Sus scrofa A0A287A009 R-SSC-3928624 https://reactome.org/PathwayBrowser/#/R-SSC-3928624 EPHBs bind EFNBs IEA Sus scrofa A0A287A009 R-SSC-3928625 https://reactome.org/PathwayBrowser/#/R-SSC-3928625 PAKs autophosphorylate IEA Sus scrofa A0A287A009 R-SSC-3928627 https://reactome.org/PathwayBrowser/#/R-SSC-3928627 EPHB phosphorylates TIAM1 IEA Sus scrofa A0A287A009 R-SSC-3928628 https://reactome.org/PathwayBrowser/#/R-SSC-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa A0A287A009 R-SSC-3928631 https://reactome.org/PathwayBrowser/#/R-SSC-3928631 GIT1 binds bPIX IEA Sus scrofa A0A287A009 R-SSC-3928633 https://reactome.org/PathwayBrowser/#/R-SSC-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Sus scrofa A0A287A009 R-SSC-3928639 https://reactome.org/PathwayBrowser/#/R-SSC-3928639 p-EFNB binds GRB4 IEA Sus scrofa A0A287A009 R-SSC-3928640 https://reactome.org/PathwayBrowser/#/R-SSC-3928640 PAKs phosphorylate MLC IEA Sus scrofa A0A287A009 R-SSC-3928641 https://reactome.org/PathwayBrowser/#/R-SSC-3928641 PAK binds RAC and bPIX IEA Sus scrofa A0A287A009 R-SSC-3928645 https://reactome.org/PathwayBrowser/#/R-SSC-3928645 EPHB:NMDAR binds TIAM1 IEA Sus scrofa A0A287A009 R-SSC-3928657 https://reactome.org/PathwayBrowser/#/R-SSC-3928657 MMP2,9 cleave EPHB IEA Sus scrofa A0A287A009 R-SSC-4093329 https://reactome.org/PathwayBrowser/#/R-SSC-4093329 EFNBs bind SDCBP IEA Sus scrofa A0A287A009 R-SSC-4093331 https://reactome.org/PathwayBrowser/#/R-SSC-4093331 Ras:GTP binds p120-RasGAP IEA Sus scrofa A0A287A009 R-SSC-4093332 https://reactome.org/PathwayBrowser/#/R-SSC-4093332 p-EPHB phosphorylates SDC2 IEA Sus scrofa A0A287A009 R-SSC-4093336 https://reactome.org/PathwayBrowser/#/R-SSC-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa A0A287A009 R-SSC-4093339 https://reactome.org/PathwayBrowser/#/R-SSC-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Sus scrofa A0A287A041 R-SSC-1483089 https://reactome.org/PathwayBrowser/#/R-SSC-1483089 PE is converted to PS by PTDSS2 IEA Sus scrofa A0A287A042 R-SSC-189102 https://reactome.org/PathwayBrowser/#/R-SSC-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Sus scrofa A0A287A042 R-SSC-191116 https://reactome.org/PathwayBrowser/#/R-SSC-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Sus scrofa A0A287A042 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A287A042 R-SSC-6800426 https://reactome.org/PathwayBrowser/#/R-SSC-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Sus scrofa A0A287A053 R-SSC-5626981 https://reactome.org/PathwayBrowser/#/R-SSC-5626981 TNF-α:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 IEA Sus scrofa A0A287A053 R-SSC-5626982 https://reactome.org/PathwayBrowser/#/R-SSC-5626982 TNF-α:TNFR1:NSMAF binds RACK1 IEA Sus scrofa A0A287A053 R-SSC-5626988 https://reactome.org/PathwayBrowser/#/R-SSC-5626988 TNF-α:TNFR1 binds NSMAF IEA Sus scrofa A0A287A061 R-SSC-191352 https://reactome.org/PathwayBrowser/#/R-SSC-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Sus scrofa A0A287A061 R-SSC-9705584 https://reactome.org/PathwayBrowser/#/R-SSC-9705584 HMGCR dimer binds statins IEA Sus scrofa A0A287A065 R-SSC-6785342 https://reactome.org/PathwayBrowser/#/R-SSC-6785342 FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex IEA Sus scrofa A0A287A065 R-SSC-6785361 https://reactome.org/PathwayBrowser/#/R-SSC-6785361 Monoubiquitination of FANCD2:FANCI IEA Sus scrofa A0A287A065 R-SSC-6785594 https://reactome.org/PathwayBrowser/#/R-SSC-6785594 FANCD2 binds FANCI IEA Sus scrofa A0A287A065 R-SSC-6785732 https://reactome.org/PathwayBrowser/#/R-SSC-6785732 DNA nucleases bind monoubiquitinated ID2 complex IEA Sus scrofa A0A287A065 R-SSC-6785986 https://reactome.org/PathwayBrowser/#/R-SSC-6785986 DNA nucleases unhook the interstrand crosslink (ICL) IEA Sus scrofa A0A287A065 R-SSC-6786155 https://reactome.org/PathwayBrowser/#/R-SSC-6786155 POLN binds ICL-DNA IEA Sus scrofa A0A287A065 R-SSC-6786166 https://reactome.org/PathwayBrowser/#/R-SSC-6786166 Translesion synthesis across unhooked ICL by POLN IEA Sus scrofa A0A287A065 R-SSC-6786171 https://reactome.org/PathwayBrowser/#/R-SSC-6786171 FANCD2 deubiquitination by USP1:WDR48 IEA Sus scrofa A0A287A065 R-SSC-6788385 https://reactome.org/PathwayBrowser/#/R-SSC-6788385 The complex of ATR and ATRIP is recruited to ICL-DNA IEA Sus scrofa A0A287A065 R-SSC-6788392 https://reactome.org/PathwayBrowser/#/R-SSC-6788392 ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA IEA Sus scrofa A0A287A070 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A070 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287A070 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A070 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A070 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A070 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287A070 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287A070 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287A070 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287A075 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A075 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287A075 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A075 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A075 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A075 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287A075 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287A075 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287A075 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287A083 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287A083 R-SSC-417843 https://reactome.org/PathwayBrowser/#/R-SSC-417843 P2Y13 binds ADP IEA Sus scrofa A0A287A083 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287A083 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287A096 R-SSC-156808 https://reactome.org/PathwayBrowser/#/R-SSC-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Sus scrofa A0A287A096 R-SSC-156823 https://reactome.org/PathwayBrowser/#/R-SSC-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Sus scrofa A0A287A096 R-SSC-157849 https://reactome.org/PathwayBrowser/#/R-SSC-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Sus scrofa A0A287A096 R-SSC-381111 https://reactome.org/PathwayBrowser/#/R-SSC-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Sus scrofa A0A287A096 R-SSC-5227009 https://reactome.org/PathwayBrowser/#/R-SSC-5227009 ABCF1 binds EIF2 IEA Sus scrofa A0A287A096 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa A0A287A096 R-SSC-72663 https://reactome.org/PathwayBrowser/#/R-SSC-72663 De novo formation of eIF2:GTP IEA Sus scrofa A0A287A096 R-SSC-72669 https://reactome.org/PathwayBrowser/#/R-SSC-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Sus scrofa A0A287A096 R-SSC-72670 https://reactome.org/PathwayBrowser/#/R-SSC-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Sus scrofa A0A287A096 R-SSC-72691 https://reactome.org/PathwayBrowser/#/R-SSC-72691 Formation of the 43S pre-initiation complex IEA Sus scrofa A0A287A096 R-SSC-72697 https://reactome.org/PathwayBrowser/#/R-SSC-72697 Start codon recognition IEA Sus scrofa A0A287A096 R-SSC-72722 https://reactome.org/PathwayBrowser/#/R-SSC-72722 eIF2 activation IEA Sus scrofa A0A287A096 R-SSC-9840415 https://reactome.org/PathwayBrowser/#/R-SSC-9840415 DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) IEA Sus scrofa A0A287A0B5 R-SSC-2162186 https://reactome.org/PathwayBrowser/#/R-SSC-2162186 COQ3 methylates DeMQ10H2 IEA Sus scrofa A0A287A0B5 R-SSC-2162187 https://reactome.org/PathwayBrowser/#/R-SSC-2162187 COQ6 hydroxylates DHB IEA Sus scrofa A0A287A0B5 R-SSC-2162188 https://reactome.org/PathwayBrowser/#/R-SSC-2162188 COQ5 methylates MDMQ10H2 IEA Sus scrofa A0A287A0B5 R-SSC-2162193 https://reactome.org/PathwayBrowser/#/R-SSC-2162193 COQ3 methylates DHDB IEA Sus scrofa A0A287A0B5 R-SSC-2162194 https://reactome.org/PathwayBrowser/#/R-SSC-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Sus scrofa A0A287A0B5 R-SSC-2162195 https://reactome.org/PathwayBrowser/#/R-SSC-2162195 COQ4 decarboxylates MHDB IEA Sus scrofa A0A287A0C6 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287A0D0 R-SSC-6805103 https://reactome.org/PathwayBrowser/#/R-SSC-6805103 AURKA phosphorylates TP53 IEA Sus scrofa A0A287A0D0 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A287A0D0 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A287A0D5 R-SSC-8952626 https://reactome.org/PathwayBrowser/#/R-SSC-8952626 AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A0D5 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287A0D5 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A0D5 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A0E9 R-SSC-2684901 https://reactome.org/PathwayBrowser/#/R-SSC-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Sus scrofa A0A287A0E9 R-SSC-2744242 https://reactome.org/PathwayBrowser/#/R-SSC-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Sus scrofa A0A287A0E9 R-SSC-2744361 https://reactome.org/PathwayBrowser/#/R-SSC-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Sus scrofa A0A287A0E9 R-SSC-5333671 https://reactome.org/PathwayBrowser/#/R-SSC-5333671 CLCAs self cleave IEA Sus scrofa A0A287A0E9 R-SSC-9659568 https://reactome.org/PathwayBrowser/#/R-SSC-9659568 ANO1 transports cytosolic Cl- to extracellular region IEA Sus scrofa A0A287A0H1 R-SSC-74372 https://reactome.org/PathwayBrowser/#/R-SSC-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Sus scrofa A0A287A0H1 R-SSC-74376 https://reactome.org/PathwayBrowser/#/R-SSC-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Sus scrofa A0A287A0J6 R-SSC-8878664 https://reactome.org/PathwayBrowser/#/R-SSC-8878664 SLC4A4 cotransports Na+ with 3HCO3- IEA Sus scrofa A0A287A0K2 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A287A0K2 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A287A0K2 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A287A0K2 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A287A0K2 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A287A0K4 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A287A0K4 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A287A0K4 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A287A0K4 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A287A0K4 R-SSC-3772435 https://reactome.org/PathwayBrowser/#/R-SSC-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Sus scrofa A0A287A0K4 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A287A0K4 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A287A0K4 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A287A0K4 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A287A0K4 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A287A0K4 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287A0K4 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A287A0K4 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A287A0K4 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287A0K4 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A287A0K4 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287A0K4 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287A0K4 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287A0K4 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287A0K4 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287A0K4 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A287A0K4 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A287A0L0 R-SSC-5675947 https://reactome.org/PathwayBrowser/#/R-SSC-5675947 TNFSF18 binds TNFRSF18 IEA Sus scrofa A0A287A0M2 R-SSC-1614362 https://reactome.org/PathwayBrowser/#/R-SSC-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Sus scrofa A0A287A0P1 R-SSC-8954468 https://reactome.org/PathwayBrowser/#/R-SSC-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP IEA Sus scrofa A0A287A0R9 R-SSC-2744361 https://reactome.org/PathwayBrowser/#/R-SSC-2744361 BESTs transport cytosolic Cl- to extracellular region IEA Sus scrofa A0A287A0R9 R-SSC-2752067 https://reactome.org/PathwayBrowser/#/R-SSC-2752067 BESTs transport cytosolic HCO3- to extracellular region IEA Sus scrofa A0A287A0T6 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287A0U5 R-SSC-4085217 https://reactome.org/PathwayBrowser/#/R-SSC-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Sus scrofa A0A287A0V4 R-SSC-75079 https://reactome.org/PathwayBrowser/#/R-SSC-75079 Formation of AT-AC C complex IEA Sus scrofa A0A287A0V4 R-SSC-75081 https://reactome.org/PathwayBrowser/#/R-SSC-75081 Formation of AT-AC B Complex IEA Sus scrofa A0A287A0V4 R-SSC-75082 https://reactome.org/PathwayBrowser/#/R-SSC-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Sus scrofa A0A287A0V4 R-SSC-75083 https://reactome.org/PathwayBrowser/#/R-SSC-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Sus scrofa A0A287A0V4 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287A0W1 R-SSC-5631903 https://reactome.org/PathwayBrowser/#/R-SSC-5631903 SESN1,2,3 bind overoxidized PRDX1 IEA Sus scrofa A0A287A0W1 R-SSC-5631941 https://reactome.org/PathwayBrowser/#/R-SSC-5631941 SESN1,2,3 bind AMPK IEA Sus scrofa A0A287A0W1 R-SSC-9639287 https://reactome.org/PathwayBrowser/#/R-SSC-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Sus scrofa A0A287A0W1 R-SSC-9640195 https://reactome.org/PathwayBrowser/#/R-SSC-9640195 RRAGA,B hydrolyzes GTP IEA Sus scrofa A0A287A0W1 R-SSC-9766645 https://reactome.org/PathwayBrowser/#/R-SSC-9766645 CUL3:RBX1 ubiquitinates KEAP1 IEA Sus scrofa A0A287A0W1 R-SSC-9766656 https://reactome.org/PathwayBrowser/#/R-SSC-9766656 RBX1:CUL3 dissociates from forming autophagosome IEA Sus scrofa A0A287A0W1 R-SSC-9766677 https://reactome.org/PathwayBrowser/#/R-SSC-9766677 MAP1LC3B binds KEAP1 and SQSTM1 IEA Sus scrofa A0A287A0W1 R-SSC-9766687 https://reactome.org/PathwayBrowser/#/R-SSC-9766687 SESN1,SESN1 bind SQSTM1 and KEAP1 IEA Sus scrofa A0A287A0W5 R-SSC-5610767 https://reactome.org/PathwayBrowser/#/R-SSC-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Sus scrofa A0A287A0W5 R-SSC-5624949 https://reactome.org/PathwayBrowser/#/R-SSC-5624949 Assembly of the anterograde IFT train IEA Sus scrofa A0A287A0W5 R-SSC-5624952 https://reactome.org/PathwayBrowser/#/R-SSC-5624952 Assembly of the retrograde IFT train IEA Sus scrofa A0A287A0W5 R-SSC-5625416 https://reactome.org/PathwayBrowser/#/R-SSC-5625416 Anterograde IFT IEA Sus scrofa A0A287A0W5 R-SSC-5625421 https://reactome.org/PathwayBrowser/#/R-SSC-5625421 The anterograde IFT train dissociates IEA Sus scrofa A0A287A0W5 R-SSC-5625424 https://reactome.org/PathwayBrowser/#/R-SSC-5625424 The retrograde IFT train dissociates IEA Sus scrofa A0A287A0W5 R-SSC-5625426 https://reactome.org/PathwayBrowser/#/R-SSC-5625426 Retrograde IFT IEA Sus scrofa A0A287A0W5 R-SSC-9641096 https://reactome.org/PathwayBrowser/#/R-SSC-9641096 Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub IEA Sus scrofa A0A287A0W5 R-SSC-9641111 https://reactome.org/PathwayBrowser/#/R-SSC-9641111 Parkin transfers Ub to misfolded proteins IEA Sus scrofa A0A287A0W5 R-SSC-9641127 https://reactome.org/PathwayBrowser/#/R-SSC-9641127 Ub:misfolded proteins polymerize to PolyUb:misfolded proteins IEA Sus scrofa A0A287A0W5 R-SSC-9646348 https://reactome.org/PathwayBrowser/#/R-SSC-9646348 PolyUb-Misfolded Proteins:HDAC6 bind dynein motor IEA Sus scrofa A0A287A0W5 R-SSC-9646679 https://reactome.org/PathwayBrowser/#/R-SSC-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Sus scrofa A0A287A0W5 R-SSC-9646685 https://reactome.org/PathwayBrowser/#/R-SSC-9646685 Aggresome dissociates from dynein and microtubule IEA Sus scrofa A0A287A0W8 R-SSC-6814549 https://reactome.org/PathwayBrowser/#/R-SSC-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Sus scrofa A0A287A0W8 R-SSC-6814555 https://reactome.org/PathwayBrowser/#/R-SSC-6814555 Integrator complex processes the 3' end of snRNA IEA Sus scrofa A0A287A0W8 R-SSC-6814559 https://reactome.org/PathwayBrowser/#/R-SSC-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Sus scrofa A0A287A0W8 R-SSC-6814885 https://reactome.org/PathwayBrowser/#/R-SSC-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Sus scrofa A0A287A0W9 R-SSC-3132753 https://reactome.org/PathwayBrowser/#/R-SSC-3132753 Pancreatic proteases degrade TCN1:RCbl IEA Sus scrofa A0A287A0W9 R-SSC-3132759 https://reactome.org/PathwayBrowser/#/R-SSC-3132759 TCN1 binds RCbl IEA Sus scrofa A0A287A0W9 R-SSC-3245898 https://reactome.org/PathwayBrowser/#/R-SSC-3245898 TCN1 binds correnoids in the circulation IEA Sus scrofa A0A287A0W9 R-SSC-6798745 https://reactome.org/PathwayBrowser/#/R-SSC-6798745 Exocytosis of tertiary granule lumen proteins IEA Sus scrofa A0A287A0W9 R-SSC-6798749 https://reactome.org/PathwayBrowser/#/R-SSC-6798749 Exocytosis of specific granule lumen proteins IEA Sus scrofa A0A287A0X1 R-SSC-211960 https://reactome.org/PathwayBrowser/#/R-SSC-211960 CYP2U1 19-hydroxylates ARA IEA Sus scrofa A0A287A0X1 R-SSC-2161814 https://reactome.org/PathwayBrowser/#/R-SSC-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Sus scrofa A0A287A0X1 R-SSC-2161940 https://reactome.org/PathwayBrowser/#/R-SSC-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Sus scrofa A0A287A0X8 R-SSC-6798745 https://reactome.org/PathwayBrowser/#/R-SSC-6798745 Exocytosis of tertiary granule lumen proteins IEA Sus scrofa A0A287A0Z9 R-SSC-3295579 https://reactome.org/PathwayBrowser/#/R-SSC-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Sus scrofa A0A287A102 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287A102 R-SSC-391939 https://reactome.org/PathwayBrowser/#/R-SSC-391939 TP receptor can bind thromboxane IEA Sus scrofa A0A287A102 R-SSC-428749 https://reactome.org/PathwayBrowser/#/R-SSC-428749 Activated TP receptor binds G-proten Gq IEA Sus scrofa A0A287A102 R-SSC-428750 https://reactome.org/PathwayBrowser/#/R-SSC-428750 Gq activation by TP receptor IEA Sus scrofa A0A287A102 R-SSC-428752 https://reactome.org/PathwayBrowser/#/R-SSC-428752 Dissociation of the TP:Gq complex IEA Sus scrofa A0A287A102 R-SSC-428909 https://reactome.org/PathwayBrowser/#/R-SSC-428909 Activated TP receptor binds G-protein G13 IEA Sus scrofa A0A287A102 R-SSC-428917 https://reactome.org/PathwayBrowser/#/R-SSC-428917 G13 activation by TP receptor IEA Sus scrofa A0A287A102 R-SSC-428918 https://reactome.org/PathwayBrowser/#/R-SSC-428918 Dissociation of the TP:G13 complex IEA Sus scrofa A0A287A102 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287A102 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287A102 R-SSC-751019 https://reactome.org/PathwayBrowser/#/R-SSC-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Sus scrofa A0A287A102 R-SSC-751027 https://reactome.org/PathwayBrowser/#/R-SSC-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Sus scrofa A0A287A102 R-SSC-751029 https://reactome.org/PathwayBrowser/#/R-SSC-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Sus scrofa A0A287A102 R-SSC-9674529 https://reactome.org/PathwayBrowser/#/R-SSC-9674529 AAMP binds to TBXA2R IEA Sus scrofa A0A287A113 R-SSC-392054 https://reactome.org/PathwayBrowser/#/R-SSC-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Sus scrofa A0A287A113 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287A113 R-SSC-6807875 https://reactome.org/PathwayBrowser/#/R-SSC-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Sus scrofa A0A287A113 R-SSC-6807877 https://reactome.org/PathwayBrowser/#/R-SSC-6807877 ARFGAPs stimulate ARF GTPase activity IEA Sus scrofa A0A287A113 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa A0A287A113 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A287A113 R-SSC-6809011 https://reactome.org/PathwayBrowser/#/R-SSC-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Sus scrofa A0A287A119 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A287A119 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A287A119 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A287A119 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A287A119 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A287A138 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287A138 R-SSC-389481 https://reactome.org/PathwayBrowser/#/R-SSC-389481 Orexin 1 receptor can bind orexin-A neuropeptide IEA Sus scrofa A0A287A138 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287A138 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287A143 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A287A143 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A287A143 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A287A143 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A287A143 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A287A144 R-SSC-449829 https://reactome.org/PathwayBrowser/#/R-SSC-449829 IL11 binds IL11RA IEA Sus scrofa A0A287A144 R-SSC-449976 https://reactome.org/PathwayBrowser/#/R-SSC-449976 IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) IEA Sus scrofa A0A287A149 R-SSC-9033499 https://reactome.org/PathwayBrowser/#/R-SSC-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Sus scrofa A0A287A149 R-SSC-9033516 https://reactome.org/PathwayBrowser/#/R-SSC-9033516 PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Sus scrofa A0A287A149 R-SSC-9033533 https://reactome.org/PathwayBrowser/#/R-SSC-9033533 PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Sus scrofa A0A287A159 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A287A159 R-SSC-9014294 https://reactome.org/PathwayBrowser/#/R-SSC-9014294 RAC2 binds effectors at the plasma membrane IEA Sus scrofa A0A287A159 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa A0A287A178 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A287A178 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A287A178 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287A178 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287A178 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287A178 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287A178 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287A178 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287A178 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287A178 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287A178 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287A189 R-SSC-9865630 https://reactome.org/PathwayBrowser/#/R-SSC-9865630 Metallochaperone inserts 2Cu2+ into MT-CO2 IEA Sus scrofa A0A287A189 R-SSC-9902096 https://reactome.org/PathwayBrowser/#/R-SSC-9902096 COX18 inserts nascent MT-CO2 in COX20:TMEM77 IEA Sus scrofa A0A287A191 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A287A191 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A287A191 R-SSC-6814695 https://reactome.org/PathwayBrowser/#/R-SSC-6814695 PERP binds desmosomes IEA Sus scrofa A0A287A191 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A287A198 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287A1A1 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A287A1A1 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A287A1A1 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A287A1A1 R-SSC-6800426 https://reactome.org/PathwayBrowser/#/R-SSC-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Sus scrofa A0A287A1A8 R-SSC-389889 https://reactome.org/PathwayBrowser/#/R-SSC-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Sus scrofa A0A287A1A9 R-SSC-426240 https://reactome.org/PathwayBrowser/#/R-SSC-426240 DAG kinase produces phosphatidic acid from DAG IEA Sus scrofa A0A287A1B8 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A287A1B8 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A287A1B8 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A287A1B8 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A287A1B8 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287A1B8 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287A1B8 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287A1B8 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287A1B8 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287A1B8 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287A1B8 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A287A1B8 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A287A1B8 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A287A1B8 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A287A1B8 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287A1C0 R-SSC-5675373 https://reactome.org/PathwayBrowser/#/R-SSC-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Sus scrofa A0A287A1C0 R-SSC-5675376 https://reactome.org/PathwayBrowser/#/R-SSC-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Sus scrofa A0A287A1C3 R-SSC-388828 https://reactome.org/PathwayBrowser/#/R-SSC-388828 PD-1 binds B7DC and B7H1 IEA Sus scrofa A0A287A1C3 R-SSC-389758 https://reactome.org/PathwayBrowser/#/R-SSC-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Sus scrofa A0A287A1C3 R-SSC-389759 https://reactome.org/PathwayBrowser/#/R-SSC-389759 Interaction of SHP-1 or SHP-2 with phospho PD-1 IEA Sus scrofa A0A287A1C3 R-SSC-389762 https://reactome.org/PathwayBrowser/#/R-SSC-389762 Phosphorylation of PD-1 IEA Sus scrofa A0A287A1C3 R-SSC-9679421 https://reactome.org/PathwayBrowser/#/R-SSC-9679421 PDCD1 binds PDCD1 inhibitors IEA Sus scrofa A0A287A1C6 R-SSC-5610735 https://reactome.org/PathwayBrowser/#/R-SSC-5610735 NUMB binds ITCH IEA Sus scrofa A0A287A1C6 R-SSC-5610737 https://reactome.org/PathwayBrowser/#/R-SSC-5610737 NUMB:ITCH bind and ubiquitnate GLI1 IEA Sus scrofa A0A287A1C6 R-SSC-5610760 https://reactome.org/PathwayBrowser/#/R-SSC-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Sus scrofa A0A287A1C6 R-SSC-5635861 https://reactome.org/PathwayBrowser/#/R-SSC-5635861 NUMB:ITCH binds GLI1 IEA Sus scrofa A0A287A1C6 R-SSC-5635864 https://reactome.org/PathwayBrowser/#/R-SSC-5635864 NUMB:ITCH ubiquitinates GLI1 IEA Sus scrofa A0A287A1C6 R-SSC-5635868 https://reactome.org/PathwayBrowser/#/R-SSC-5635868 ub-GLI is degraded by the proteasome IEA Sus scrofa A0A287A1D7 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287A1E1 R-SSC-6801242 https://reactome.org/PathwayBrowser/#/R-SSC-6801242 TRIAP1 binds PRELID1, PRELID3A IEA Sus scrofa A0A287A1E1 R-SSC-6801250 https://reactome.org/PathwayBrowser/#/R-SSC-6801250 TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane IEA Sus scrofa A0A287A1E6 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A287A1E6 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287A1E7 R-SSC-1678842 https://reactome.org/PathwayBrowser/#/R-SSC-1678842 Competitive inhibition of translation initiation by ISGylated 4EHP IEA Sus scrofa A0A287A1F4 R-SSC-5696872 https://reactome.org/PathwayBrowser/#/R-SSC-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Sus scrofa A0A287A1F4 R-SSC-9018814 https://reactome.org/PathwayBrowser/#/R-SSC-9018814 RHOT1 hydrolyzes GTP IEA Sus scrofa A0A287A1F4 R-SSC-9018815 https://reactome.org/PathwayBrowser/#/R-SSC-9018815 RHOT1 binds effectors at the mitochondrial outer membrane IEA Sus scrofa A0A287A1F6 R-SSC-5682388 https://reactome.org/PathwayBrowser/#/R-SSC-5682388 Autophagosome maturation IEA Sus scrofa A0A287A1F6 R-SSC-917693 https://reactome.org/PathwayBrowser/#/R-SSC-917693 ESCRT Disassembly IEA Sus scrofa A0A287A1F6 R-SSC-917700 https://reactome.org/PathwayBrowser/#/R-SSC-917700 MVB Vesicle Formation IEA Sus scrofa A0A287A1F6 R-SSC-9647619 https://reactome.org/PathwayBrowser/#/R-SSC-9647619 GSDMD forms ring‐shaped oligomers IEA Sus scrofa A0A287A1F6 R-SSC-9668389 https://reactome.org/PathwayBrowser/#/R-SSC-9668389 VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations IEA Sus scrofa A0A287A1F6 R-SSC-9668395 https://reactome.org/PathwayBrowser/#/R-SSC-9668395 CHMP7 binds CC2D1B IEA Sus scrofa A0A287A1F6 R-SSC-9668405 https://reactome.org/PathwayBrowser/#/R-SSC-9668405 SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin IEA Sus scrofa A0A287A1F6 R-SSC-9668419 https://reactome.org/PathwayBrowser/#/R-SSC-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Sus scrofa A0A287A1I4 R-SSC-2076611 https://reactome.org/PathwayBrowser/#/R-SSC-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Sus scrofa A0A287A1J0 R-SSC-3247837 https://reactome.org/PathwayBrowser/#/R-SSC-3247837 WNT ligands traffic to the Golgi IEA Sus scrofa A0A287A1J0 R-SSC-3247840 https://reactome.org/PathwayBrowser/#/R-SSC-3247840 WLS binds WNT ligands in the Golgi IEA Sus scrofa A0A287A1J0 R-SSC-3247843 https://reactome.org/PathwayBrowser/#/R-SSC-3247843 secretion of WNT ligands IEA Sus scrofa A0A287A1J0 R-SSC-3247844 https://reactome.org/PathwayBrowser/#/R-SSC-3247844 WNT ligands traffic to the plasma membrane IEA Sus scrofa A0A287A1J0 R-SSC-3781941 https://reactome.org/PathwayBrowser/#/R-SSC-3781941 WNTs are secreted in exosomes IEA Sus scrofa A0A287A1J0 R-SSC-3781943 https://reactome.org/PathwayBrowser/#/R-SSC-3781943 WLS:WNT complex is internalized for maturation into exosomes IEA Sus scrofa A0A287A1J0 R-SSC-3858482 https://reactome.org/PathwayBrowser/#/R-SSC-3858482 DVL is recruited to the receptor IEA Sus scrofa A0A287A1J0 R-SSC-3965444 https://reactome.org/PathwayBrowser/#/R-SSC-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Sus scrofa A0A287A1J0 R-SSC-3965447 https://reactome.org/PathwayBrowser/#/R-SSC-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Sus scrofa A0A287A1J0 R-SSC-5099886 https://reactome.org/PathwayBrowser/#/R-SSC-5099886 WNT5A binding to FZD promotes PRICKLE1 degradation IEA Sus scrofa A0A287A1J0 R-SSC-5099899 https://reactome.org/PathwayBrowser/#/R-SSC-5099899 WNT5A binds FZD4 IEA Sus scrofa A0A287A1J0 R-SSC-5138432 https://reactome.org/PathwayBrowser/#/R-SSC-5138432 DVL2 is phosphorylated by PKC IEA Sus scrofa A0A287A1J0 R-SSC-5138433 https://reactome.org/PathwayBrowser/#/R-SSC-5138433 p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis IEA Sus scrofa A0A287A1J0 R-SSC-5138441 https://reactome.org/PathwayBrowser/#/R-SSC-5138441 WNT5A-FZD4 recruits DVL2 IEA Sus scrofa A0A287A1J0 R-SSC-5138459 https://reactome.org/PathwayBrowser/#/R-SSC-5138459 WNT5A:FZD4 is endocytosed IEA Sus scrofa A0A287A1J0 R-SSC-5140741 https://reactome.org/PathwayBrowser/#/R-SSC-5140741 WNT5A binds FZD and ROR receptors IEA Sus scrofa A0A287A1J0 R-SSC-5140747 https://reactome.org/PathwayBrowser/#/R-SSC-5140747 FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner IEA Sus scrofa A0A287A1J0 R-SSC-5323545 https://reactome.org/PathwayBrowser/#/R-SSC-5323545 Canonical WNT signaling through the atypical receptor RYK IEA Sus scrofa A0A287A1J0 R-SSC-8866269 https://reactome.org/PathwayBrowser/#/R-SSC-8866269 ARRB bind GPCRs IEA Sus scrofa A0A287A1J0 R-SSC-8866283 https://reactome.org/PathwayBrowser/#/R-SSC-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Sus scrofa A0A287A1J0 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A287A1J0 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A287A1J0 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A287A1J0 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A287A1J0 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A287A1J0 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287A1J0 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287A1J0 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287A1J0 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287A1J0 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287A1J0 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287A1J0 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287A1J0 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287A1J0 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287A1K8 R-SSC-9907919 https://reactome.org/PathwayBrowser/#/R-SSC-9907919 Formation of the preholoproteasome IEA Sus scrofa A0A287A1K8 R-SSC-9907940 https://reactome.org/PathwayBrowser/#/R-SSC-9907940 Formation of the preholothymoproteasome IEA Sus scrofa A0A287A1K8 R-SSC-9907941 https://reactome.org/PathwayBrowser/#/R-SSC-9907941 Fromation of the preholoimmunoproteasome IEA Sus scrofa A0A287A1K8 R-SSC-9908069 https://reactome.org/PathwayBrowser/#/R-SSC-9908069 POMP binds the 20S core particle outer ring IEA Sus scrofa A0A287A1L0 R-SSC-2028555 https://reactome.org/PathwayBrowser/#/R-SSC-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Sus scrofa A0A287A1L0 R-SSC-2028583 https://reactome.org/PathwayBrowser/#/R-SSC-2028583 Phosphorylation of YAP by LATS2 IEA Sus scrofa A0A287A1L0 R-SSC-2028589 https://reactome.org/PathwayBrowser/#/R-SSC-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Sus scrofa A0A287A1L0 R-SSC-2028626 https://reactome.org/PathwayBrowser/#/R-SSC-2028626 Phosphorylated MOB1A proteins associate with LATS proteins IEA Sus scrofa A0A287A1L0 R-SSC-2028661 https://reactome.org/PathwayBrowser/#/R-SSC-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Sus scrofa A0A287A1L0 R-SSC-2028673 https://reactome.org/PathwayBrowser/#/R-SSC-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Sus scrofa A0A287A1L0 R-SSC-2028679 https://reactome.org/PathwayBrowser/#/R-SSC-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Sus scrofa A0A287A1L0 R-SSC-2038398 https://reactome.org/PathwayBrowser/#/R-SSC-2038398 KIBRA (WWC1) binds LATS proteins IEA Sus scrofa A0A287A1L0 R-SSC-2059926 https://reactome.org/PathwayBrowser/#/R-SSC-2059926 NPHP4 protein binds LATS proteins IEA Sus scrofa A0A287A1M9 R-SSC-5620914 https://reactome.org/PathwayBrowser/#/R-SSC-5620914 ARF4:GTP binds VxPx-motifs of membrane proteins IEA Sus scrofa A0A287A1M9 R-SSC-5620921 https://reactome.org/PathwayBrowser/#/R-SSC-5620921 ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex IEA Sus scrofa A0A287A1M9 R-SSC-5623508 https://reactome.org/PathwayBrowser/#/R-SSC-5623508 GBF1 stimulates nucleotide exchange on ARF4 IEA Sus scrofa A0A287A1M9 R-SSC-5623513 https://reactome.org/PathwayBrowser/#/R-SSC-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Sus scrofa A0A287A1M9 R-SSC-6807868 https://reactome.org/PathwayBrowser/#/R-SSC-6807868 GBF1 stimulates ARF nucleotide exchange IEA Sus scrofa A0A287A1M9 R-SSC-6807872 https://reactome.org/PathwayBrowser/#/R-SSC-6807872 Active ARF recruits coatomer IEA Sus scrofa A0A287A1M9 R-SSC-6807875 https://reactome.org/PathwayBrowser/#/R-SSC-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Sus scrofa A0A287A1M9 R-SSC-6807877 https://reactome.org/PathwayBrowser/#/R-SSC-6807877 ARFGAPs stimulate ARF GTPase activity IEA Sus scrofa A0A287A1M9 R-SSC-6811417 https://reactome.org/PathwayBrowser/#/R-SSC-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Sus scrofa A0A287A1M9 R-SSC-6811418 https://reactome.org/PathwayBrowser/#/R-SSC-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Sus scrofa A0A287A1R2 R-SSC-914010 https://reactome.org/PathwayBrowser/#/R-SSC-914010 Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein IEA Sus scrofa A0A287A1S4 R-SSC-5654985 https://reactome.org/PathwayBrowser/#/R-SSC-5654985 SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH IEA Sus scrofa A0A287A1S4 R-SSC-5654989 https://reactome.org/PathwayBrowser/#/R-SSC-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Sus scrofa A0A287A1S4 R-SSC-6781922 https://reactome.org/PathwayBrowser/#/R-SSC-6781922 USP13 binds UFD1L:SKP2 IEA Sus scrofa A0A287A1S4 R-SSC-9755507 https://reactome.org/PathwayBrowser/#/R-SSC-9755507 UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex IEA Sus scrofa A0A287A1S4 R-SSC-9758088 https://reactome.org/PathwayBrowser/#/R-SSC-9758088 UBXN7 binds VCP hexamer:UBF1:NPLOC4 IEA Sus scrofa A0A287A1S4 R-SSC-9758090 https://reactome.org/PathwayBrowser/#/R-SSC-9758090 Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation IEA Sus scrofa A0A287A1S5 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa A0A287A1S5 R-SSC-2160931 https://reactome.org/PathwayBrowser/#/R-SSC-2160931 Disassembly of tight junctions IEA Sus scrofa A0A287A1S5 R-SSC-2160932 https://reactome.org/PathwayBrowser/#/R-SSC-2160932 SMURF1 binds phosphorylated PARD6A IEA Sus scrofa A0A287A1S5 R-SSC-2160935 https://reactome.org/PathwayBrowser/#/R-SSC-2160935 SMURF1 ubiquitinates RHOA IEA Sus scrofa A0A287A1S5 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa A0A287A1S5 R-SSC-8980691 https://reactome.org/PathwayBrowser/#/R-SSC-8980691 RHOA GEFs activate RHOA IEA Sus scrofa A0A287A1S5 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A287A1S6 R-SSC-114577 https://reactome.org/PathwayBrowser/#/R-SSC-114577 Binding of GPVI:Fc Epsilon R1 gamma receptor complex with collagen IEA Sus scrofa A0A287A1S6 R-SSC-114600 https://reactome.org/PathwayBrowser/#/R-SSC-114600 Fyn/Lyn-mediated phosphorylation of FcR1 gamma IEA Sus scrofa A0A287A1S6 R-SSC-114670 https://reactome.org/PathwayBrowser/#/R-SSC-114670 GPIb-IX-V binds to vWF:Collagen complex IEA Sus scrofa A0A287A1S6 R-SSC-114671 https://reactome.org/PathwayBrowser/#/R-SSC-114671 vWF binds to collagen IEA Sus scrofa A0A287A1S6 R-SSC-139842 https://reactome.org/PathwayBrowser/#/R-SSC-139842 Binding of Syk tyrosine kinase IEA Sus scrofa A0A287A1S6 R-SSC-1454757 https://reactome.org/PathwayBrowser/#/R-SSC-1454757 Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 IEA Sus scrofa A0A287A1S6 R-SSC-1454822 https://reactome.org/PathwayBrowser/#/R-SSC-1454822 Collagen type I degradation by MMP1,2,8,13, PRSS2 IEA Sus scrofa A0A287A1S6 R-SSC-1474266 https://reactome.org/PathwayBrowser/#/R-SSC-1474266 Formation of collagen fibrils IEA Sus scrofa A0A287A1S6 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa A0A287A1S6 R-SSC-1981104 https://reactome.org/PathwayBrowser/#/R-SSC-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Sus scrofa A0A287A1S6 R-SSC-1981120 https://reactome.org/PathwayBrowser/#/R-SSC-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Sus scrofa A0A287A1S6 R-SSC-1981128 https://reactome.org/PathwayBrowser/#/R-SSC-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Sus scrofa A0A287A1S6 R-SSC-1981157 https://reactome.org/PathwayBrowser/#/R-SSC-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Sus scrofa A0A287A1S6 R-SSC-2002428 https://reactome.org/PathwayBrowser/#/R-SSC-2002428 Removal of fibrillar collagen N-propeptides IEA Sus scrofa A0A287A1S6 R-SSC-2002440 https://reactome.org/PathwayBrowser/#/R-SSC-2002440 Removal of fibrillar collagen C-propeptides IEA Sus scrofa A0A287A1S6 R-SSC-2002460 https://reactome.org/PathwayBrowser/#/R-SSC-2002460 P4HB binds Collagen chains IEA Sus scrofa A0A287A1S6 R-SSC-2002466 https://reactome.org/PathwayBrowser/#/R-SSC-2002466 Formation of allysine by LOX IEA Sus scrofa A0A287A1S6 R-SSC-2089971 https://reactome.org/PathwayBrowser/#/R-SSC-2089971 Secretion of collagens IEA Sus scrofa A0A287A1S6 R-SSC-216045 https://reactome.org/PathwayBrowser/#/R-SSC-216045 Collagen type I binds integrin alpha11beta1 IEA Sus scrofa A0A287A1S6 R-SSC-2213201 https://reactome.org/PathwayBrowser/#/R-SSC-2213201 Formation of collagen fibres IEA Sus scrofa A0A287A1S6 R-SSC-2213205 https://reactome.org/PathwayBrowser/#/R-SSC-2213205 Type XII and XIV collagens associate with type I and type II fibrils IEA Sus scrofa A0A287A1S6 R-SSC-2243926 https://reactome.org/PathwayBrowser/#/R-SSC-2243926 Formation of histidino-hydroxylysinonorleucine cross-links IEA Sus scrofa A0A287A1S6 R-SSC-2243931 https://reactome.org/PathwayBrowser/#/R-SSC-2243931 Formation of dehydro-lysinonorleucine cross-links IEA Sus scrofa A0A287A1S6 R-SSC-2250301 https://reactome.org/PathwayBrowser/#/R-SSC-2250301 Formation of lysyl-pyrrole cross-links IEA Sus scrofa A0A287A1S6 R-SSC-2327733 https://reactome.org/PathwayBrowser/#/R-SSC-2327733 FN1 binds Collagen types I-V, VII IEA Sus scrofa A0A287A1S6 R-SSC-2327738 https://reactome.org/PathwayBrowser/#/R-SSC-2327738 DDR1 binds collagen type I, II, III, IV, V, XI fibrils IEA Sus scrofa A0A287A1S6 R-SSC-2327909 https://reactome.org/PathwayBrowser/#/R-SSC-2327909 DCN binds collagen I, II, III, VI fibrils IEA Sus scrofa A0A287A1S6 R-SSC-2395223 https://reactome.org/PathwayBrowser/#/R-SSC-2395223 Formation of hydroxylysyl-pyridinoline cross-links IEA Sus scrofa A0A287A1S6 R-SSC-2395257 https://reactome.org/PathwayBrowser/#/R-SSC-2395257 Formation of dehydro-hydroxylysino-norleucine cross-links IEA Sus scrofa A0A287A1S6 R-SSC-2395302 https://reactome.org/PathwayBrowser/#/R-SSC-2395302 Formation of hydroxylysino-5-ketonorleucine cross-links IEA Sus scrofa A0A287A1S6 R-SSC-2395314 https://reactome.org/PathwayBrowser/#/R-SSC-2395314 Formation of lysino-5-ketonorleucine cross-links IEA Sus scrofa A0A287A1S6 R-SSC-2395322 https://reactome.org/PathwayBrowser/#/R-SSC-2395322 Formation of lysyl-pyridinoline cross-links IEA Sus scrofa A0A287A1S6 R-SSC-2395324 https://reactome.org/PathwayBrowser/#/R-SSC-2395324 Formation of hydroxylysyl-pyrrole cross-links IEA Sus scrofa A0A287A1S6 R-SSC-2395340 https://reactome.org/PathwayBrowser/#/R-SSC-2395340 Formation of hydroxyallysine by LOX IEA Sus scrofa A0A287A1S6 R-SSC-2424243 https://reactome.org/PathwayBrowser/#/R-SSC-2424243 SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ IEA Sus scrofa A0A287A1S6 R-SSC-2424252 https://reactome.org/PathwayBrowser/#/R-SSC-2424252 COMP binds collagen, fibronectin, aggrecan and matrilins IEA Sus scrofa A0A287A1S6 R-SSC-2465890 https://reactome.org/PathwayBrowser/#/R-SSC-2465890 DDR2 binds collagen type I, II, III, V, X fibrils IEA Sus scrofa A0A287A1S6 R-SSC-2466106 https://reactome.org/PathwayBrowser/#/R-SSC-2466106 BGN binds Collagen types I, VI, (IX) IEA Sus scrofa A0A287A1S6 R-SSC-2473596 https://reactome.org/PathwayBrowser/#/R-SSC-2473596 Collagen type I degradation by MMP15 IEA Sus scrofa A0A287A1S6 R-SSC-429529 https://reactome.org/PathwayBrowser/#/R-SSC-429529 Thrombin binding to GP1b:IX:V IEA Sus scrofa A0A287A1S6 R-SSC-430073 https://reactome.org/PathwayBrowser/#/R-SSC-430073 GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress IEA Sus scrofa A0A287A1S6 R-SSC-430076 https://reactome.org/PathwayBrowser/#/R-SSC-430076 GP1b-IX-V binds 14-3-3-zeta IEA Sus scrofa A0A287A1S6 R-SSC-430096 https://reactome.org/PathwayBrowser/#/R-SSC-430096 GP1b-IX-V binds filamin IEA Sus scrofa A0A287A1S6 R-SSC-437118 https://reactome.org/PathwayBrowser/#/R-SSC-437118 GPVI stimulates PI3K beta, gamma IEA Sus scrofa A0A287A1S6 R-SSC-443402 https://reactome.org/PathwayBrowser/#/R-SSC-443402 GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K IEA Sus scrofa A0A287A1S6 R-SSC-443418 https://reactome.org/PathwayBrowser/#/R-SSC-443418 GP1b signaling involves c-Src IEA Sus scrofa A0A287A1S6 R-SSC-453183 https://reactome.org/PathwayBrowser/#/R-SSC-453183 p-Y348-SYK dissociates IEA Sus scrofa A0A287A1S6 R-SSC-453200 https://reactome.org/PathwayBrowser/#/R-SSC-453200 SYK autophosphorylates IEA Sus scrofa A0A287A1S6 R-SSC-5696356 https://reactome.org/PathwayBrowser/#/R-SSC-5696356 OSCAR binds collagen and SP-D IEA Sus scrofa A0A287A1S6 R-SSC-5696357 https://reactome.org/PathwayBrowser/#/R-SSC-5696357 LAIR2 binds collagen IEA Sus scrofa A0A287A1S6 R-SSC-8944214 https://reactome.org/PathwayBrowser/#/R-SSC-8944214 Association of procollagen type I IEA Sus scrofa A0A287A1S6 R-SSC-8948219 https://reactome.org/PathwayBrowser/#/R-SSC-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A287A1S6 R-SSC-8948222 https://reactome.org/PathwayBrowser/#/R-SSC-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287A1S6 R-SSC-8948224 https://reactome.org/PathwayBrowser/#/R-SSC-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287A1S6 R-SSC-8948228 https://reactome.org/PathwayBrowser/#/R-SSC-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A287A1S6 R-SSC-8948231 https://reactome.org/PathwayBrowser/#/R-SSC-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287A1S6 R-SSC-8948232 https://reactome.org/PathwayBrowser/#/R-SSC-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Sus scrofa A0A287A1S6 R-SSC-8948234 https://reactome.org/PathwayBrowser/#/R-SSC-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Sus scrofa A0A287A1S6 R-SSC-9822532 https://reactome.org/PathwayBrowser/#/R-SSC-9822532 ADAMTS13 cleaves VWF multimer IEA Sus scrofa A0A287A1S6 R-SSC-9822539 https://reactome.org/PathwayBrowser/#/R-SSC-9822539 VWF multimer binds to collagen type I IEA Sus scrofa A0A287A1S6 R-SSC-9823065 https://reactome.org/PathwayBrowser/#/R-SSC-9823065 GPIb:IX:V binds to VWF multimer:collagen IEA Sus scrofa A0A287A1U8 R-SSC-5676917 https://reactome.org/PathwayBrowser/#/R-SSC-5676917 MRSBs reduce L-methyl-(R)-S-oxide to L-methionine IEA Sus scrofa A0A287A1V9 R-SSC-75883 https://reactome.org/PathwayBrowser/#/R-SSC-75883 DHRS7B reduces GO3P to HXDG3P IEA Sus scrofa A0A287A1W6 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A287A1W6 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A287A1W6 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A287A1W6 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A287A1W6 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287A1W6 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287A1W6 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287A1W6 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287A1W6 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287A1W6 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287A1W6 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A287A1W6 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A287A1W6 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A287A1W6 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A287A1W6 R-SSC-606287 https://reactome.org/PathwayBrowser/#/R-SSC-606287 RSF complex binds the centromere IEA Sus scrofa A0A287A1W6 R-SSC-606326 https://reactome.org/PathwayBrowser/#/R-SSC-606326 HJURP:CENPA complex localizes to the centromere IEA Sus scrofa A0A287A1W6 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287A1X4 R-SSC-446202 https://reactome.org/PathwayBrowser/#/R-SSC-446202 Addition of the first glucose to the N-glycan precursor by ALG6 IEA Sus scrofa A0A287A1X6 R-SSC-191972 https://reactome.org/PathwayBrowser/#/R-SSC-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Sus scrofa A0A287A1X6 R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa A0A287A1X6 R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa A0A287A1X6 R-SSC-194187 https://reactome.org/PathwayBrowser/#/R-SSC-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Sus scrofa A0A287A1X6 R-SSC-376419 https://reactome.org/PathwayBrowser/#/R-SSC-376419 Formation of NR-MED1 Coactivator Complex IEA Sus scrofa A0A287A1X6 R-SSC-382096 https://reactome.org/PathwayBrowser/#/R-SSC-382096 Formation of NR-NCOR Corepressor Complex IEA Sus scrofa A0A287A1X6 R-SSC-4755419 https://reactome.org/PathwayBrowser/#/R-SSC-4755419 SUMOylation of NR1H4 with SUMO1 IEA Sus scrofa A0A287A1X6 R-SSC-5340195 https://reactome.org/PathwayBrowser/#/R-SSC-5340195 NR1H4 binds DCA, CDCA, LCHA IEA Sus scrofa A0A287A1X6 R-SSC-5340251 https://reactome.org/PathwayBrowser/#/R-SSC-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Sus scrofa A0A287A210 R-SSC-1678841 https://reactome.org/PathwayBrowser/#/R-SSC-1678841 Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 IEA Sus scrofa A0A287A210 R-SSC-5696534 https://reactome.org/PathwayBrowser/#/R-SSC-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Sus scrofa A0A287A210 R-SSC-912685 https://reactome.org/PathwayBrowser/#/R-SSC-912685 UBP43 binds IFNAR2 and prevents JAK1 interaction IEA Sus scrofa A0A287A210 R-SSC-9758604 https://reactome.org/PathwayBrowser/#/R-SSC-9758604 Ubiquitination of IKBKG by TRAF6 IEA Sus scrofa A0A287A210 R-SSC-9761344 https://reactome.org/PathwayBrowser/#/R-SSC-9761344 USP18 binds IKBKG within IKK complex IEA Sus scrofa A0A287A217 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287A217 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287A217 R-SSC-190520 https://reactome.org/PathwayBrowser/#/R-SSC-190520 Association of Golgi transport vesicles with microtubules IEA Sus scrofa A0A287A217 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A287A217 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287A217 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287A217 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287A217 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287A217 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A287A217 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A287A217 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A287A217 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A287A217 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A287A217 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A287A217 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A287A217 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A287A217 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A287A217 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A287A217 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287A217 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A287A217 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A287A217 R-SSC-5610733 https://reactome.org/PathwayBrowser/#/R-SSC-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules IEA Sus scrofa A0A287A217 R-SSC-5610767 https://reactome.org/PathwayBrowser/#/R-SSC-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Sus scrofa A0A287A217 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287A217 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa A0A287A217 R-SSC-5618328 https://reactome.org/PathwayBrowser/#/R-SSC-5618328 ATAT acetylates microtubules IEA Sus scrofa A0A287A217 R-SSC-5618331 https://reactome.org/PathwayBrowser/#/R-SSC-5618331 HDAC6 deacetylates microtubules IEA Sus scrofa A0A287A217 R-SSC-5624949 https://reactome.org/PathwayBrowser/#/R-SSC-5624949 Assembly of the anterograde IFT train IEA Sus scrofa A0A287A217 R-SSC-5624952 https://reactome.org/PathwayBrowser/#/R-SSC-5624952 Assembly of the retrograde IFT train IEA Sus scrofa A0A287A217 R-SSC-5625416 https://reactome.org/PathwayBrowser/#/R-SSC-5625416 Anterograde IFT IEA Sus scrofa A0A287A217 R-SSC-5625421 https://reactome.org/PathwayBrowser/#/R-SSC-5625421 The anterograde IFT train dissociates IEA Sus scrofa A0A287A217 R-SSC-5625424 https://reactome.org/PathwayBrowser/#/R-SSC-5625424 The retrograde IFT train dissociates IEA Sus scrofa A0A287A217 R-SSC-5625426 https://reactome.org/PathwayBrowser/#/R-SSC-5625426 Retrograde IFT IEA Sus scrofa A0A287A217 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A287A217 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287A217 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287A217 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287A217 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287A217 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287A217 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A287A217 R-SSC-5672329 https://reactome.org/PathwayBrowser/#/R-SSC-5672329 IQGAP1 binds CLIP1 and microtubules IEA Sus scrofa A0A287A217 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A287A217 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa A0A287A217 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A287A217 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa A0A287A217 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa A0A287A217 R-SSC-8852280 https://reactome.org/PathwayBrowser/#/R-SSC-8852280 GTSE1 binds microtubule lattice in interphase cells IEA Sus scrofa A0A287A217 R-SSC-8852298 https://reactome.org/PathwayBrowser/#/R-SSC-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends IEA Sus scrofa A0A287A217 R-SSC-8852306 https://reactome.org/PathwayBrowser/#/R-SSC-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Sus scrofa A0A287A217 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A287A217 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A287A217 R-SSC-8865774 https://reactome.org/PathwayBrowser/#/R-SSC-8865774 TTLLs polyglutamylate tubulin IEA Sus scrofa A0A287A217 R-SSC-8867370 https://reactome.org/PathwayBrowser/#/R-SSC-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Sus scrofa A0A287A217 R-SSC-9646679 https://reactome.org/PathwayBrowser/#/R-SSC-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Sus scrofa A0A287A217 R-SSC-9646685 https://reactome.org/PathwayBrowser/#/R-SSC-9646685 Aggresome dissociates from dynein and microtubule IEA Sus scrofa A0A287A217 R-SSC-9648017 https://reactome.org/PathwayBrowser/#/R-SSC-9648017 EML4 binds to microtubules IEA Sus scrofa A0A287A217 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287A217 R-SSC-9668419 https://reactome.org/PathwayBrowser/#/R-SSC-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Sus scrofa A0A287A217 R-SSC-983259 https://reactome.org/PathwayBrowser/#/R-SSC-983259 Kinesins move along microtubules consuming ATP IEA Sus scrofa A0A287A217 R-SSC-983266 https://reactome.org/PathwayBrowser/#/R-SSC-983266 Kinesins bind microtubules IEA Sus scrofa A0A287A217 R-SSC-9836404 https://reactome.org/PathwayBrowser/#/R-SSC-9836404 p-PKR dimer phosphorylates MAPT IEA Sus scrofa A0A287A226 R-SSC-939763 https://reactome.org/PathwayBrowser/#/R-SSC-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Sus scrofa A0A287A226 R-SSC-947591 https://reactome.org/PathwayBrowser/#/R-SSC-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Sus scrofa A0A287A228 R-SSC-6807875 https://reactome.org/PathwayBrowser/#/R-SSC-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Sus scrofa A0A287A228 R-SSC-6807877 https://reactome.org/PathwayBrowser/#/R-SSC-6807877 ARFGAPs stimulate ARF GTPase activity IEA Sus scrofa A0A287A228 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa A0A287A228 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A287A228 R-SSC-6809011 https://reactome.org/PathwayBrowser/#/R-SSC-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Sus scrofa A0A287A228 R-SSC-6811417 https://reactome.org/PathwayBrowser/#/R-SSC-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Sus scrofa A0A287A228 R-SSC-6811418 https://reactome.org/PathwayBrowser/#/R-SSC-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Sus scrofa A0A287A228 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa A0A287A228 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa A0A287A231 R-SSC-1250195 https://reactome.org/PathwayBrowser/#/R-SSC-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Sus scrofa A0A287A231 R-SSC-1306957 https://reactome.org/PathwayBrowser/#/R-SSC-1306957 PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Sus scrofa A0A287A231 R-SSC-1306963 https://reactome.org/PathwayBrowser/#/R-SSC-1306963 Binding of GRB2:GAB1 to p-ERBB2:p-EGFR IEA Sus scrofa A0A287A231 R-SSC-1306965 https://reactome.org/PathwayBrowser/#/R-SSC-1306965 Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR IEA Sus scrofa A0A287A231 R-SSC-177922 https://reactome.org/PathwayBrowser/#/R-SSC-177922 EGFR dimerization IEA Sus scrofa A0A287A231 R-SSC-177923 https://reactome.org/PathwayBrowser/#/R-SSC-177923 Sustained activation of SRC kinase by SHP2 IEA Sus scrofa A0A287A231 R-SSC-177924 https://reactome.org/PathwayBrowser/#/R-SSC-177924 Dephosphorylation of Gab1 by SHP2 IEA Sus scrofa A0A287A231 R-SSC-177925 https://reactome.org/PathwayBrowser/#/R-SSC-177925 SHC1 binds to the phosphorylated EGF receptor:ligand complex IEA Sus scrofa A0A287A231 R-SSC-177926 https://reactome.org/PathwayBrowser/#/R-SSC-177926 Dephosphorylation of PAG by SHP2 IEA Sus scrofa A0A287A231 R-SSC-177927 https://reactome.org/PathwayBrowser/#/R-SSC-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 IEA Sus scrofa A0A287A231 R-SSC-177930 https://reactome.org/PathwayBrowser/#/R-SSC-177930 GAB1 phosphorylation by EGFR kinase IEA Sus scrofa A0A287A231 R-SSC-177933 https://reactome.org/PathwayBrowser/#/R-SSC-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Sus scrofa A0A287A231 R-SSC-177934 https://reactome.org/PathwayBrowser/#/R-SSC-177934 EGFR autophosphorylation IEA Sus scrofa A0A287A231 R-SSC-177935 https://reactome.org/PathwayBrowser/#/R-SSC-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Sus scrofa A0A287A231 R-SSC-177936 https://reactome.org/PathwayBrowser/#/R-SSC-177936 GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR IEA Sus scrofa A0A287A231 R-SSC-177937 https://reactome.org/PathwayBrowser/#/R-SSC-177937 Phosphorylation of EGFR by SRC kinase IEA Sus scrofa A0A287A231 R-SSC-177938 https://reactome.org/PathwayBrowser/#/R-SSC-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Sus scrofa A0A287A231 R-SSC-177939 https://reactome.org/PathwayBrowser/#/R-SSC-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Sus scrofa A0A287A231 R-SSC-177941 https://reactome.org/PathwayBrowser/#/R-SSC-177941 GRB2:GAB1 binds to phosphorylated EGFR IEA Sus scrofa A0A287A231 R-SSC-177942 https://reactome.org/PathwayBrowser/#/R-SSC-177942 EGFR binds EGF ligand IEA Sus scrofa A0A287A231 R-SSC-177943 https://reactome.org/PathwayBrowser/#/R-SSC-177943 GRB2:SOS1 complex binds to EGF:EGFR complex IEA Sus scrofa A0A287A231 R-SSC-177944 https://reactome.org/PathwayBrowser/#/R-SSC-177944 Activation of SHP2 through the binding to phospho-Gab1 IEA Sus scrofa A0A287A231 R-SSC-177945 https://reactome.org/PathwayBrowser/#/R-SSC-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Sus scrofa A0A287A231 R-SSC-182969 https://reactome.org/PathwayBrowser/#/R-SSC-182969 Phosphorylation of CBL (EGFR:CBL) IEA Sus scrofa A0A287A231 R-SSC-182986 https://reactome.org/PathwayBrowser/#/R-SSC-182986 CBL-mediated ubiquitination of CIN85 IEA Sus scrofa A0A287A231 R-SSC-182990 https://reactome.org/PathwayBrowser/#/R-SSC-182990 Sprouty sequesters CBL away from active EGFR IEA Sus scrofa A0A287A231 R-SSC-182993 https://reactome.org/PathwayBrowser/#/R-SSC-182993 Ubiquitination of stimulated EGFR (CBL) IEA Sus scrofa A0A287A231 R-SSC-182994 https://reactome.org/PathwayBrowser/#/R-SSC-182994 Assembly of EGFR complex in clathrin-coated vesicles IEA Sus scrofa A0A287A231 R-SSC-183002 https://reactome.org/PathwayBrowser/#/R-SSC-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Sus scrofa A0A287A231 R-SSC-183036 https://reactome.org/PathwayBrowser/#/R-SSC-183036 Ubiquitination of stimulated EGFR (CBL:GRB2) IEA Sus scrofa A0A287A231 R-SSC-183051 https://reactome.org/PathwayBrowser/#/R-SSC-183051 CBL ubiquitinates Sprouty IEA Sus scrofa A0A287A231 R-SSC-183055 https://reactome.org/PathwayBrowser/#/R-SSC-183055 Binding of CBL to EGFR IEA Sus scrofa A0A287A231 R-SSC-183058 https://reactome.org/PathwayBrowser/#/R-SSC-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Sus scrofa A0A287A231 R-SSC-183067 https://reactome.org/PathwayBrowser/#/R-SSC-183067 Localization of CBL:GRB2 to the membrane IEA Sus scrofa A0A287A231 R-SSC-183072 https://reactome.org/PathwayBrowser/#/R-SSC-183072 EGFR non-clathrin mediated endocytosis IEA Sus scrofa A0A287A231 R-SSC-183084 https://reactome.org/PathwayBrowser/#/R-SSC-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Sus scrofa A0A287A231 R-SSC-183089 https://reactome.org/PathwayBrowser/#/R-SSC-183089 CBL binds and ubiquitinates phosphorylated Sprouty IEA Sus scrofa A0A287A231 R-SSC-1963563 https://reactome.org/PathwayBrowser/#/R-SSC-1963563 MATK (CSK homologous kinase) binds phosphorylated ERBB2 IEA Sus scrofa A0A287A231 R-SSC-1963581 https://reactome.org/PathwayBrowser/#/R-SSC-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Sus scrofa A0A287A231 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa A0A287A231 R-SSC-1963586 https://reactome.org/PathwayBrowser/#/R-SSC-1963586 SRC family kinases phosphorylate ERBB2 IEA Sus scrofa A0A287A231 R-SSC-1977959 https://reactome.org/PathwayBrowser/#/R-SSC-1977959 ERBB4 forms heterodimers with EGFR IEA Sus scrofa A0A287A231 R-SSC-212706 https://reactome.org/PathwayBrowser/#/R-SSC-212706 Phospholipase C-gamma1 binds to the activated EGF receptor IEA Sus scrofa A0A287A231 R-SSC-212710 https://reactome.org/PathwayBrowser/#/R-SSC-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Sus scrofa A0A287A231 R-SSC-212713 https://reactome.org/PathwayBrowser/#/R-SSC-212713 Active PLC-gamma1 dissociates from EGFR IEA Sus scrofa A0A287A231 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287A231 R-SSC-481007 https://reactome.org/PathwayBrowser/#/R-SSC-481007 Exocytosis of platelet alpha granule contents IEA Sus scrofa A0A287A231 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287A231 R-SSC-6785636 https://reactome.org/PathwayBrowser/#/R-SSC-6785636 Phosphorylated ERBB2 heterodimers bind MEMO1 IEA Sus scrofa A0A287A231 R-SSC-6785648 https://reactome.org/PathwayBrowser/#/R-SSC-6785648 MEMO1 binds RHOA:GTP:DIAPH1 IEA Sus scrofa A0A287A231 R-SSC-8847995 https://reactome.org/PathwayBrowser/#/R-SSC-8847995 Activated ERBB2 binds PTK6 (BRK) IEA Sus scrofa A0A287A231 R-SSC-8848005 https://reactome.org/PathwayBrowser/#/R-SSC-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Sus scrofa A0A287A231 R-SSC-8857925 https://reactome.org/PathwayBrowser/#/R-SSC-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Sus scrofa A0A287A231 R-SSC-8863804 https://reactome.org/PathwayBrowser/#/R-SSC-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Sus scrofa A0A287A231 R-SSC-8864029 https://reactome.org/PathwayBrowser/#/R-SSC-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Sus scrofa A0A287A231 R-SSC-8864105 https://reactome.org/PathwayBrowser/#/R-SSC-8864105 PTPN18 binds ERBB2:EGFR heterodimers IEA Sus scrofa A0A287A231 R-SSC-8864125 https://reactome.org/PathwayBrowser/#/R-SSC-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Sus scrofa A0A287A231 R-SSC-8866279 https://reactome.org/PathwayBrowser/#/R-SSC-8866279 Epsin family proteins bind ubiquitinated cargo IEA Sus scrofa A0A287A231 R-SSC-8867041 https://reactome.org/PathwayBrowser/#/R-SSC-8867041 EGFR phosphorylates EPS15 IEA Sus scrofa A0A287A231 R-SSC-8867044 https://reactome.org/PathwayBrowser/#/R-SSC-8867044 EGFR binds EPS15, EPN1, EPS15L1 IEA Sus scrofa A0A287A231 R-SSC-8867047 https://reactome.org/PathwayBrowser/#/R-SSC-8867047 PTPN3 dephosphorylates EPS15 IEA Sus scrofa A0A287A231 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A287A231 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A287A231 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A287A231 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A287A231 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A287A231 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287A231 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287A231 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287A231 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287A231 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287A231 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287A231 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287A231 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287A231 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287A231 R-SSC-8951490 https://reactome.org/PathwayBrowser/#/R-SSC-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Sus scrofa A0A287A266 R-SSC-111879 https://reactome.org/PathwayBrowser/#/R-SSC-111879 PIP2 hydrolysis IEA Sus scrofa A0A287A266 R-SSC-112037 https://reactome.org/PathwayBrowser/#/R-SSC-112037 Inactivation of PLC beta IEA Sus scrofa A0A287A266 R-SSC-114688 https://reactome.org/PathwayBrowser/#/R-SSC-114688 PLC-beta hydrolyses PIP2 to DAG and IP3 IEA Sus scrofa A0A287A266 R-SSC-1855177 https://reactome.org/PathwayBrowser/#/R-SSC-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Sus scrofa A0A287A283 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287A283 R-SSC-380076 https://reactome.org/PathwayBrowser/#/R-SSC-380076 Tachykinin receptor 1 (NK1) binds to substance P IEA Sus scrofa A0A287A283 R-SSC-383363 https://reactome.org/PathwayBrowser/#/R-SSC-383363 Tachykinin receptor 2 (NK2) binds to nuerokinin A IEA Sus scrofa A0A287A283 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287A283 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287A286 R-SSC-156826 https://reactome.org/PathwayBrowser/#/R-SSC-156826 Dissociation of L13a from the 60s ribosomal subunit IEA Sus scrofa A0A287A286 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A287A286 R-SSC-6791218 https://reactome.org/PathwayBrowser/#/R-SSC-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Sus scrofa A0A287A286 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A287A286 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A287A286 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A287A286 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A287A286 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A287A286 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A287A286 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A287A286 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A287A2B7 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287A2D7 R-SSC-5617828 https://reactome.org/PathwayBrowser/#/R-SSC-5617828 TRIP11:IFT20 dissociates IEA Sus scrofa A0A287A2D7 R-SSC-8847875 https://reactome.org/PathwayBrowser/#/R-SSC-8847875 ARF1:GTP binds Golgin TRIP11 IEA Sus scrofa A0A287A2E5 R-SSC-2029465 https://reactome.org/PathwayBrowser/#/R-SSC-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Sus scrofa A0A287A2E5 R-SSC-2029466 https://reactome.org/PathwayBrowser/#/R-SSC-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Sus scrofa A0A287A2E5 R-SSC-2029469 https://reactome.org/PathwayBrowser/#/R-SSC-2029469 p-ERK phosphorylates WAVEs and ABI IEA Sus scrofa A0A287A2E5 R-SSC-2130194 https://reactome.org/PathwayBrowser/#/R-SSC-2130194 ABL phosphorylates WAVEs IEA Sus scrofa A0A287A2E5 R-SSC-2197690 https://reactome.org/PathwayBrowser/#/R-SSC-2197690 Detachment of WASP/WAVE IEA Sus scrofa A0A287A2E5 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A287A2E5 R-SSC-9014294 https://reactome.org/PathwayBrowser/#/R-SSC-9014294 RAC2 binds effectors at the plasma membrane IEA Sus scrofa A0A287A2E5 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa A0A287A2E8 R-SSC-202710 https://reactome.org/PathwayBrowser/#/R-SSC-202710 MERTK receptor binds ligands (Gas6 or Protein S) IEA Sus scrofa A0A287A2F9 R-SSC-112379 https://reactome.org/PathwayBrowser/#/R-SSC-112379 Recruitment of elongation factors to form elongation complex IEA Sus scrofa A0A287A2F9 R-SSC-112385 https://reactome.org/PathwayBrowser/#/R-SSC-112385 Addition of nucleotides leads to transcript elongation IEA Sus scrofa A0A287A2F9 R-SSC-112392 https://reactome.org/PathwayBrowser/#/R-SSC-112392 Resumption of elongation after recovery from pausing IEA Sus scrofa A0A287A2F9 R-SSC-112395 https://reactome.org/PathwayBrowser/#/R-SSC-112395 Abortive termination of elongation after arrest IEA Sus scrofa A0A287A2F9 R-SSC-112396 https://reactome.org/PathwayBrowser/#/R-SSC-112396 Separation of elongating transcript from template IEA Sus scrofa A0A287A2F9 R-SSC-113411 https://reactome.org/PathwayBrowser/#/R-SSC-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Sus scrofa A0A287A2F9 R-SSC-113412 https://reactome.org/PathwayBrowser/#/R-SSC-113412 Pol II elongation complex moves on the template as transcript elongates IEA Sus scrofa A0A287A2F9 R-SSC-113413 https://reactome.org/PathwayBrowser/#/R-SSC-113413 TFIIS-mediated recovery of elongation from arrest IEA Sus scrofa A0A287A2F9 R-SSC-113414 https://reactome.org/PathwayBrowser/#/R-SSC-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Sus scrofa A0A287A2F9 R-SSC-113429 https://reactome.org/PathwayBrowser/#/R-SSC-113429 Elongating transcript encounters a lesion in the template IEA Sus scrofa A0A287A2F9 R-SSC-6782004 https://reactome.org/PathwayBrowser/#/R-SSC-6782004 Assembly of the pre-incision complex in TC-NER IEA Sus scrofa A0A287A2F9 R-SSC-6782069 https://reactome.org/PathwayBrowser/#/R-SSC-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Sus scrofa A0A287A2F9 R-SSC-6782131 https://reactome.org/PathwayBrowser/#/R-SSC-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa A0A287A2F9 R-SSC-6782138 https://reactome.org/PathwayBrowser/#/R-SSC-6782138 ERCC5 and RPA bind TC-NER site IEA Sus scrofa A0A287A2F9 R-SSC-6782141 https://reactome.org/PathwayBrowser/#/R-SSC-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Sus scrofa A0A287A2F9 R-SSC-6782204 https://reactome.org/PathwayBrowser/#/R-SSC-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Sus scrofa A0A287A2F9 R-SSC-6782208 https://reactome.org/PathwayBrowser/#/R-SSC-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Sus scrofa A0A287A2F9 R-SSC-6782211 https://reactome.org/PathwayBrowser/#/R-SSC-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Sus scrofa A0A287A2F9 R-SSC-6782224 https://reactome.org/PathwayBrowser/#/R-SSC-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Sus scrofa A0A287A2F9 R-SSC-6782227 https://reactome.org/PathwayBrowser/#/R-SSC-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Sus scrofa A0A287A2F9 R-SSC-6797606 https://reactome.org/PathwayBrowser/#/R-SSC-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Sus scrofa A0A287A2F9 R-SSC-6797616 https://reactome.org/PathwayBrowser/#/R-SSC-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Sus scrofa A0A287A2F9 R-SSC-9684118 https://reactome.org/PathwayBrowser/#/R-SSC-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa A0A287A2G0 R-SSC-416320 https://reactome.org/PathwayBrowser/#/R-SSC-416320 Trafficking of GluR1-containing AMPA receptors IEA Sus scrofa A0A287A2G0 R-SSC-5682794 https://reactome.org/PathwayBrowser/#/R-SSC-5682794 LGI1 binds ADAM22 and ADAM23 IEA Sus scrofa A0A287A2G6 R-SSC-3341296 https://reactome.org/PathwayBrowser/#/R-SSC-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Sus scrofa A0A287A2G9 R-SSC-6805546 https://reactome.org/PathwayBrowser/#/R-SSC-6805546 Keratin type I binds keratin type II IEA Sus scrofa A0A287A2G9 R-SSC-6805573 https://reactome.org/PathwayBrowser/#/R-SSC-6805573 Keratin type I/type II heterodimers form tetramers IEA Sus scrofa A0A287A2G9 R-SSC-6806610 https://reactome.org/PathwayBrowser/#/R-SSC-6806610 Keratin filament formation IEA Sus scrofa A0A287A2G9 R-SSC-6806613 https://reactome.org/PathwayBrowser/#/R-SSC-6806613 Keratin tetramers bind to form unit length filaments IEA Sus scrofa A0A287A2G9 R-SSC-6806629 https://reactome.org/PathwayBrowser/#/R-SSC-6806629 Formation of tonofilament bundles IEA Sus scrofa A0A287A2G9 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A287A2G9 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287A2G9 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A287A2G9 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A287A2I2 R-SSC-197235 https://reactome.org/PathwayBrowser/#/R-SSC-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa A0A287A2I2 R-SSC-8939959 https://reactome.org/PathwayBrowser/#/R-SSC-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Sus scrofa A0A287A2I5 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287A2J5 R-SSC-9618021 https://reactome.org/PathwayBrowser/#/R-SSC-9618021 FOXG1 binds FOXO:SMAD complexes IEA Sus scrofa A0A287A2J9 R-SSC-1504190 https://reactome.org/PathwayBrowser/#/R-SSC-1504190 DVL is ubiquitinated by CUL3:KLHL12:RBX1 IEA Sus scrofa A0A287A2J9 R-SSC-1504193 https://reactome.org/PathwayBrowser/#/R-SSC-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Sus scrofa A0A287A2J9 R-SSC-1504213 https://reactome.org/PathwayBrowser/#/R-SSC-1504213 DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex IEA Sus scrofa A0A287A2J9 R-SSC-5635854 https://reactome.org/PathwayBrowser/#/R-SSC-5635854 GLI2,3 are degraded by the proteasome IEA Sus scrofa A0A287A2J9 R-SSC-5635855 https://reactome.org/PathwayBrowser/#/R-SSC-5635855 phosphorylated GLI proteins bind SPOP:CUL3:RBX1 IEA Sus scrofa A0A287A2J9 R-SSC-5635856 https://reactome.org/PathwayBrowser/#/R-SSC-5635856 SPOP:CUL3:RBX1 ubiquitinates GLI2,3 IEA Sus scrofa A0A287A2J9 R-SSC-5658424 https://reactome.org/PathwayBrowser/#/R-SSC-5658424 KBTBD7:CUL3:RBX1 ubiquitinates NF1 IEA Sus scrofa A0A287A2J9 R-SSC-8952631 https://reactome.org/PathwayBrowser/#/R-SSC-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A2J9 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287A2J9 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A2J9 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A2J9 R-SSC-9018778 https://reactome.org/PathwayBrowser/#/R-SSC-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Sus scrofa A0A287A2J9 R-SSC-9018787 https://reactome.org/PathwayBrowser/#/R-SSC-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Sus scrofa A0A287A2J9 R-SSC-9712274 https://reactome.org/PathwayBrowser/#/R-SSC-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Sus scrofa A0A287A2J9 R-SSC-9755505 https://reactome.org/PathwayBrowser/#/R-SSC-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Sus scrofa A0A287A2J9 R-SSC-9755507 https://reactome.org/PathwayBrowser/#/R-SSC-9755507 UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex IEA Sus scrofa A0A287A2J9 R-SSC-9758090 https://reactome.org/PathwayBrowser/#/R-SSC-9758090 Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation IEA Sus scrofa A0A287A2J9 R-SSC-9759169 https://reactome.org/PathwayBrowser/#/R-SSC-9759169 p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 IEA Sus scrofa A0A287A2J9 R-SSC-9759172 https://reactome.org/PathwayBrowser/#/R-SSC-9759172 KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer IEA Sus scrofa A0A287A2J9 R-SSC-9766645 https://reactome.org/PathwayBrowser/#/R-SSC-9766645 CUL3:RBX1 ubiquitinates KEAP1 IEA Sus scrofa A0A287A2J9 R-SSC-9766656 https://reactome.org/PathwayBrowser/#/R-SSC-9766656 RBX1:CUL3 dissociates from forming autophagosome IEA Sus scrofa A0A287A2J9 R-SSC-9766677 https://reactome.org/PathwayBrowser/#/R-SSC-9766677 MAP1LC3B binds KEAP1 and SQSTM1 IEA Sus scrofa A0A287A2J9 R-SSC-9766687 https://reactome.org/PathwayBrowser/#/R-SSC-9766687 SESN1,SESN1 bind SQSTM1 and KEAP1 IEA Sus scrofa A0A287A2J9 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287A2J9 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287A2J9 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287A2J9 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287A2K4 R-SSC-6797627 https://reactome.org/PathwayBrowser/#/R-SSC-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Sus scrofa A0A287A2N5 R-SSC-1011598 https://reactome.org/PathwayBrowser/#/R-SSC-1011598 DOCKs bind to RhoGEFs IEA Sus scrofa A0A287A2N5 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287A2N5 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287A2N5 R-SSC-5218811 https://reactome.org/PathwayBrowser/#/R-SSC-5218811 DOCK180:ELMO binds CRK IEA Sus scrofa A0A287A2N5 R-SSC-5218839 https://reactome.org/PathwayBrowser/#/R-SSC-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Sus scrofa A0A287A2N5 R-SSC-8848611 https://reactome.org/PathwayBrowser/#/R-SSC-8848611 Phosphorylated PXN recruits the CRK complex IEA Sus scrofa A0A287A2N5 R-SSC-8848618 https://reactome.org/PathwayBrowser/#/R-SSC-8848618 Activation of RAC1 by the PXN:CRK complex IEA Sus scrofa A0A287A2N5 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A287A2N5 R-SSC-9014296 https://reactome.org/PathwayBrowser/#/R-SSC-9014296 RAC2 GEFs activate RAC2 IEA Sus scrofa A0A287A2N5 R-SSC-9014449 https://reactome.org/PathwayBrowser/#/R-SSC-9014449 RHOG binds effectors at the plasma membrane IEA Sus scrofa A0A287A2Q3 R-SSC-6797630 https://reactome.org/PathwayBrowser/#/R-SSC-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Sus scrofa A0A287A2Q4 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A287A2Q4 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A287A2Q4 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A287A2Q4 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A287A2Q4 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A287A2Q4 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A287A2Q4 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A287A2Q4 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A287A2Q4 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A287A2Q4 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287A2Q4 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A287A2Q4 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A287A2Q4 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A287A2Q4 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287A2Q4 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287A2Q4 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287A2Q4 R-SSC-5696945 https://reactome.org/PathwayBrowser/#/R-SSC-5696945 USP33 deubiquitinates CCP110,ARRB IEA Sus scrofa A0A287A2Q4 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A287A2Q4 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A287A2Q4 R-SSC-9018794 https://reactome.org/PathwayBrowser/#/R-SSC-9018794 RHOV binds effectors at the plasma membrane IEA Sus scrofa A0A287A2Q7 R-SSC-1454757 https://reactome.org/PathwayBrowser/#/R-SSC-1454757 Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 IEA Sus scrofa A0A287A2Q7 R-SSC-1474197 https://reactome.org/PathwayBrowser/#/R-SSC-1474197 Collagen type II degradation by MMP1,3,8,13,PRSS2 IEA Sus scrofa A0A287A2Q7 R-SSC-1474266 https://reactome.org/PathwayBrowser/#/R-SSC-1474266 Formation of collagen fibrils IEA Sus scrofa A0A287A2Q7 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa A0A287A2Q7 R-SSC-1981104 https://reactome.org/PathwayBrowser/#/R-SSC-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Sus scrofa A0A287A2Q7 R-SSC-1981120 https://reactome.org/PathwayBrowser/#/R-SSC-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Sus scrofa A0A287A2Q7 R-SSC-1981128 https://reactome.org/PathwayBrowser/#/R-SSC-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Sus scrofa A0A287A2Q7 R-SSC-1981157 https://reactome.org/PathwayBrowser/#/R-SSC-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Sus scrofa A0A287A2Q7 R-SSC-2002428 https://reactome.org/PathwayBrowser/#/R-SSC-2002428 Removal of fibrillar collagen N-propeptides IEA Sus scrofa A0A287A2Q7 R-SSC-2002440 https://reactome.org/PathwayBrowser/#/R-SSC-2002440 Removal of fibrillar collagen C-propeptides IEA Sus scrofa A0A287A2Q7 R-SSC-2002460 https://reactome.org/PathwayBrowser/#/R-SSC-2002460 P4HB binds Collagen chains IEA Sus scrofa A0A287A2Q7 R-SSC-2089971 https://reactome.org/PathwayBrowser/#/R-SSC-2089971 Secretion of collagens IEA Sus scrofa A0A287A2Q7 R-SSC-216043 https://reactome.org/PathwayBrowser/#/R-SSC-216043 Collagen type II binds integrin alpha10beta1 IEA Sus scrofa A0A287A2Q7 R-SSC-2213201 https://reactome.org/PathwayBrowser/#/R-SSC-2213201 Formation of collagen fibres IEA Sus scrofa A0A287A2Q7 R-SSC-2213205 https://reactome.org/PathwayBrowser/#/R-SSC-2213205 Type XII and XIV collagens associate with type I and type II fibrils IEA Sus scrofa A0A287A2Q7 R-SSC-2213208 https://reactome.org/PathwayBrowser/#/R-SSC-2213208 Type X collagen associates with collagen type II fibrils IEA Sus scrofa A0A287A2Q7 R-SSC-2213210 https://reactome.org/PathwayBrowser/#/R-SSC-2213210 Collagen IX is cross-linked to the surface of collagen type II fibrils IEA Sus scrofa A0A287A2Q7 R-SSC-2299620 https://reactome.org/PathwayBrowser/#/R-SSC-2299620 Collagen XI cross-links with collagen II IEA Sus scrofa A0A287A2Q7 R-SSC-2327733 https://reactome.org/PathwayBrowser/#/R-SSC-2327733 FN1 binds Collagen types I-V, VII IEA Sus scrofa A0A287A2Q7 R-SSC-2327738 https://reactome.org/PathwayBrowser/#/R-SSC-2327738 DDR1 binds collagen type I, II, III, IV, V, XI fibrils IEA Sus scrofa A0A287A2Q7 R-SSC-2327909 https://reactome.org/PathwayBrowser/#/R-SSC-2327909 DCN binds collagen I, II, III, VI fibrils IEA Sus scrofa A0A287A2Q7 R-SSC-2396370 https://reactome.org/PathwayBrowser/#/R-SSC-2396370 VTN binds collagens II, III and V IEA Sus scrofa A0A287A2Q7 R-SSC-2424252 https://reactome.org/PathwayBrowser/#/R-SSC-2424252 COMP binds collagen, fibronectin, aggrecan and matrilins IEA Sus scrofa A0A287A2Q7 R-SSC-2465890 https://reactome.org/PathwayBrowser/#/R-SSC-2465890 DDR2 binds collagen type I, II, III, V, X fibrils IEA Sus scrofa A0A287A2Q7 R-SSC-2473594 https://reactome.org/PathwayBrowser/#/R-SSC-2473594 Collagen type II degradation by MMP15 IEA Sus scrofa A0A287A2Q7 R-SSC-382054 https://reactome.org/PathwayBrowser/#/R-SSC-382054 PDGF binds to extracellular matrix proteins IEA Sus scrofa A0A287A2Q7 R-SSC-5696356 https://reactome.org/PathwayBrowser/#/R-SSC-5696356 OSCAR binds collagen and SP-D IEA Sus scrofa A0A287A2Q7 R-SSC-8944263 https://reactome.org/PathwayBrowser/#/R-SSC-8944263 Association of procollagen type II IEA Sus scrofa A0A287A2Q7 R-SSC-8944266 https://reactome.org/PathwayBrowser/#/R-SSC-8944266 Association of procollagen type XI IEA Sus scrofa A0A287A2Q7 R-SSC-8948219 https://reactome.org/PathwayBrowser/#/R-SSC-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A287A2Q7 R-SSC-8948222 https://reactome.org/PathwayBrowser/#/R-SSC-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287A2Q7 R-SSC-8948224 https://reactome.org/PathwayBrowser/#/R-SSC-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287A2Q7 R-SSC-8948228 https://reactome.org/PathwayBrowser/#/R-SSC-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A287A2Q7 R-SSC-8948231 https://reactome.org/PathwayBrowser/#/R-SSC-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287A2Q7 R-SSC-8948232 https://reactome.org/PathwayBrowser/#/R-SSC-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Sus scrofa A0A287A2Q7 R-SSC-8948234 https://reactome.org/PathwayBrowser/#/R-SSC-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Sus scrofa A0A287A2R9 R-SSC-139899 https://reactome.org/PathwayBrowser/#/R-SSC-139899 Sequestration of BAD protein by 14-3-3 IEA Sus scrofa A0A287A2R9 R-SSC-139906 https://reactome.org/PathwayBrowser/#/R-SSC-139906 Activation of BAD by calcineurin IEA Sus scrofa A0A287A2R9 R-SSC-2028651 https://reactome.org/PathwayBrowser/#/R-SSC-2028651 YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) IEA Sus scrofa A0A287A2R9 R-SSC-204981 https://reactome.org/PathwayBrowser/#/R-SSC-204981 14-3-3epsilon attentuates NADE-related apoptosis IEA Sus scrofa A0A287A2R9 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A287A2R9 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A287A2R9 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A287A2R9 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A287A2R9 R-SSC-3371527 https://reactome.org/PathwayBrowser/#/R-SSC-3371527 HSF1 trimer translocates to the nucleus IEA Sus scrofa A0A287A2R9 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A287A2R9 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A287A2R9 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A287A2R9 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A287A2R9 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A287A2R9 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287A2R9 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A287A2R9 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A287A2R9 R-SSC-4793925 https://reactome.org/PathwayBrowser/#/R-SSC-4793925 p-S303,307-HSF1 binds YWHAE (14-3-3) IEA Sus scrofa A0A287A2R9 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287A2R9 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A287A2R9 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287A2R9 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287A2R9 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287A2R9 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287A2R9 R-SSC-5632732 https://reactome.org/PathwayBrowser/#/R-SSC-5632732 p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 IEA Sus scrofa A0A287A2R9 R-SSC-5632738 https://reactome.org/PathwayBrowser/#/R-SSC-5632738 DDIT4 binds 14-3-3 dimer IEA Sus scrofa A0A287A2R9 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287A2R9 R-SSC-75016 https://reactome.org/PathwayBrowser/#/R-SSC-75016 Association of p-S216-CDC25C with 14-3-3 proteins IEA Sus scrofa A0A287A2R9 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A287A2R9 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A287A2R9 R-SSC-8877612 https://reactome.org/PathwayBrowser/#/R-SSC-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Sus scrofa A0A287A2R9 R-SSC-8933452 https://reactome.org/PathwayBrowser/#/R-SSC-8933452 YWHAE dimer binds phosphorylated DENND1 proteins IEA Sus scrofa A0A287A2S8 R-SSC-6786048 https://reactome.org/PathwayBrowser/#/R-SSC-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 IEA Sus scrofa A0A287A2U2 R-SSC-416320 https://reactome.org/PathwayBrowser/#/R-SSC-416320 Trafficking of GluR1-containing AMPA receptors IEA Sus scrofa A0A287A2U2 R-SSC-6797553 https://reactome.org/PathwayBrowser/#/R-SSC-6797553 Protein 4.1 binds CASK IEA Sus scrofa A0A287A2U2 R-SSC-6797568 https://reactome.org/PathwayBrowser/#/R-SSC-6797568 NRXNs bind CASK:Protein 4.1 IEA Sus scrofa A0A287A2V4 R-SSC-5694462 https://reactome.org/PathwayBrowser/#/R-SSC-5694462 ABHD6,12 hydrolyse 3AG IEA Sus scrofa A0A287A2V5 R-SSC-9013144 https://reactome.org/PathwayBrowser/#/R-SSC-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Sus scrofa A0A287A2V5 R-SSC-9013161 https://reactome.org/PathwayBrowser/#/R-SSC-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Sus scrofa A0A287A2W4 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287A2W4 R-SSC-388560 https://reactome.org/PathwayBrowser/#/R-SSC-388560 EDNRA,EDNRB bind EDNs IEA Sus scrofa A0A287A2W4 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287A2W4 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287A2W4 R-SSC-9731924 https://reactome.org/PathwayBrowser/#/R-SSC-9731924 EDNRA binds EDNs IEA Sus scrofa A0A287A2W8 R-SSC-9630993 https://reactome.org/PathwayBrowser/#/R-SSC-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Sus scrofa A0A287A2X0 R-SSC-6805546 https://reactome.org/PathwayBrowser/#/R-SSC-6805546 Keratin type I binds keratin type II IEA Sus scrofa A0A287A2X0 R-SSC-6805573 https://reactome.org/PathwayBrowser/#/R-SSC-6805573 Keratin type I/type II heterodimers form tetramers IEA Sus scrofa A0A287A2X0 R-SSC-6806610 https://reactome.org/PathwayBrowser/#/R-SSC-6806610 Keratin filament formation IEA Sus scrofa A0A287A2X0 R-SSC-6806613 https://reactome.org/PathwayBrowser/#/R-SSC-6806613 Keratin tetramers bind to form unit length filaments IEA Sus scrofa A0A287A2X0 R-SSC-6806629 https://reactome.org/PathwayBrowser/#/R-SSC-6806629 Formation of tonofilament bundles IEA Sus scrofa A0A287A2X0 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A287A2X0 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287A2X0 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A287A2X0 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A287A2X3 R-SSC-390284 https://reactome.org/PathwayBrowser/#/R-SSC-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Sus scrofa A0A287A2X3 R-SSC-390291 https://reactome.org/PathwayBrowser/#/R-SSC-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Sus scrofa A0A287A2X3 R-SSC-9033235 https://reactome.org/PathwayBrowser/#/R-SSC-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A287A2X3 R-SSC-9033236 https://reactome.org/PathwayBrowser/#/R-SSC-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Sus scrofa A0A287A2X4 R-SSC-8864278 https://reactome.org/PathwayBrowser/#/R-SSC-8864278 AP-2 (TFAP2) transcription factors form homo- and heterodimers IEA Sus scrofa A0A287A2X4 R-SSC-8864307 https://reactome.org/PathwayBrowser/#/R-SSC-8864307 TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP IEA Sus scrofa A0A287A2X4 R-SSC-8864343 https://reactome.org/PathwayBrowser/#/R-SSC-8864343 KCTD1 binds TFAP2 homo- and heterodimers IEA Sus scrofa A0A287A2X6 R-SSC-189222 https://reactome.org/PathwayBrowser/#/R-SSC-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Sus scrofa A0A287A2X6 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A287A310 R-SSC-6813720 https://reactome.org/PathwayBrowser/#/R-SSC-6813720 NCEH1 hydrolyzes cholesterol esters IEA Sus scrofa A0A287A321 R-SSC-1482546 https://reactome.org/PathwayBrowser/#/R-SSC-1482546 2-acyl LPG is acylated to PG by CRLS1 (IM) IEA Sus scrofa A0A287A321 R-SSC-1482689 https://reactome.org/PathwayBrowser/#/R-SSC-1482689 1-acyl LPG is acylated to PG by CRLS1 (IM) IEA Sus scrofa A0A287A321 R-SSC-1483063 https://reactome.org/PathwayBrowser/#/R-SSC-1483063 PG and CDP-DAG are converted to CL by CRLS1 IEA Sus scrofa A0A287A328 R-SSC-9696271 https://reactome.org/PathwayBrowser/#/R-SSC-9696271 RND1 binds effectors IEA Sus scrofa A0A287A341 R-SSC-428205 https://reactome.org/PathwayBrowser/#/R-SSC-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Sus scrofa A0A287A349 R-SSC-3322995 https://reactome.org/PathwayBrowser/#/R-SSC-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Sus scrofa A0A287A349 R-SSC-3697894 https://reactome.org/PathwayBrowser/#/R-SSC-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Sus scrofa A0A287A349 R-SSC-9035484 https://reactome.org/PathwayBrowser/#/R-SSC-9035484 MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST IEA Sus scrofa A0A287A359 R-SSC-3095889 https://reactome.org/PathwayBrowser/#/R-SSC-3095889 MMACHC dealkylates RCbl IEA Sus scrofa A0A287A359 R-SSC-3149494 https://reactome.org/PathwayBrowser/#/R-SSC-3149494 MMACHC:cob(II)alamin binds MMADHC IEA Sus scrofa A0A287A359 R-SSC-3149519 https://reactome.org/PathwayBrowser/#/R-SSC-3149519 MMACHC decyanates CNCbl IEA Sus scrofa A0A287A359 R-SSC-3149563 https://reactome.org/PathwayBrowser/#/R-SSC-3149563 MMADHC targets transport of cytosolic cob(II)alamin to mitochondria IEA Sus scrofa A0A287A359 R-SSC-3204318 https://reactome.org/PathwayBrowser/#/R-SSC-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR IEA Sus scrofa A0A287A359 R-SSC-9759549 https://reactome.org/PathwayBrowser/#/R-SSC-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Sus scrofa A0A287A369 R-SSC-5635839 https://reactome.org/PathwayBrowser/#/R-SSC-5635839 ULK3:SUFU dissociates IEA Sus scrofa A0A287A369 R-SSC-5635842 https://reactome.org/PathwayBrowser/#/R-SSC-5635842 ULK3 phosphorylates GLI IEA Sus scrofa A0A287A381 R-SSC-76056 https://reactome.org/PathwayBrowser/#/R-SSC-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Sus scrofa A0A287A381 R-SSC-83788 https://reactome.org/PathwayBrowser/#/R-SSC-83788 Binding of TFIIIC to Type 2 promoter IEA Sus scrofa A0A287A381 R-SSC-83805 https://reactome.org/PathwayBrowser/#/R-SSC-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Sus scrofa A0A287A395 R-SSC-376419 https://reactome.org/PathwayBrowser/#/R-SSC-376419 Formation of NR-MED1 Coactivator Complex IEA Sus scrofa A0A287A395 R-SSC-382096 https://reactome.org/PathwayBrowser/#/R-SSC-382096 Formation of NR-NCOR Corepressor Complex IEA Sus scrofa A0A287A3A3 R-SSC-9693125 https://reactome.org/PathwayBrowser/#/R-SSC-9693125 RHOF binds effectors at the plasma membrane IEA Sus scrofa A0A287A3A3 R-SSC-9693198 https://reactome.org/PathwayBrowser/#/R-SSC-9693198 RHOD binds effectors at the plasma membrane IEA Sus scrofa A0A287A3A4 R-SSC-1855182 https://reactome.org/PathwayBrowser/#/R-SSC-1855182 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol IEA Sus scrofa A0A287A3A4 R-SSC-1855216 https://reactome.org/PathwayBrowser/#/R-SSC-1855216 IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol IEA Sus scrofa A0A287A3A8 R-SSC-3132737 https://reactome.org/PathwayBrowser/#/R-SSC-3132737 MAPKs phosphorylate ETS1 and ETS2 IEA Sus scrofa A0A287A3A8 R-SSC-3209165 https://reactome.org/PathwayBrowser/#/R-SSC-3209165 ID1 sequesters ETS2 IEA Sus scrofa A0A287A3B7 R-SSC-212356 https://reactome.org/PathwayBrowser/#/R-SSC-212356 Formation of CSL-NICD coactivator complex IEA Sus scrofa A0A287A3B7 R-SSC-350058 https://reactome.org/PathwayBrowser/#/R-SSC-350058 Formation of CSL NCOR corepressor complex IEA Sus scrofa A0A287A3B7 R-SSC-8878220 https://reactome.org/PathwayBrowser/#/R-SSC-8878220 RUNX3 binds the NOTCH1 coactivator complex IEA Sus scrofa A0A287A3B9 R-SSC-158546 https://reactome.org/PathwayBrowser/#/R-SSC-158546 UGTs glucuronate APAP to APAP-GlcA IEA Sus scrofa A0A287A3B9 R-SSC-9758661 https://reactome.org/PathwayBrowser/#/R-SSC-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Sus scrofa A0A287A3C8 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287A3C8 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287A3C8 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287A3C8 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287A3D1 R-SSC-176298 https://reactome.org/PathwayBrowser/#/R-SSC-176298 Activation of claspin IEA Sus scrofa A0A287A3D1 R-SSC-176318 https://reactome.org/PathwayBrowser/#/R-SSC-176318 Loading of claspin onto DNA during replication origin firing IEA Sus scrofa A0A287A3D1 R-SSC-68914 https://reactome.org/PathwayBrowser/#/R-SSC-68914 DNA polymerase alpha:primase binds at the origin IEA Sus scrofa A0A287A3D1 R-SSC-68916 https://reactome.org/PathwayBrowser/#/R-SSC-68916 DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin IEA Sus scrofa A0A287A3D1 R-SSC-68917 https://reactome.org/PathwayBrowser/#/R-SSC-68917 Cdc45 associates with the pre-replicative complex at the origin IEA Sus scrofa A0A287A3D1 R-SSC-68918 https://reactome.org/PathwayBrowser/#/R-SSC-68918 CDK and DDK associate with the Mcm10:pre-replicative complex IEA Sus scrofa A0A287A3D1 R-SSC-68954 https://reactome.org/PathwayBrowser/#/R-SSC-68954 Mcm2-7 is phosphorylated by DDK IEA Sus scrofa A0A287A3D1 R-SSC-68960 https://reactome.org/PathwayBrowser/#/R-SSC-68960 DNA polymerase epsilon binds at the origin IEA Sus scrofa A0A287A3E1 R-SSC-6788810 https://reactome.org/PathwayBrowser/#/R-SSC-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa A0A287A3G7 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287A3G8 R-SSC-203973 https://reactome.org/PathwayBrowser/#/R-SSC-203973 Vesicle budding IEA Sus scrofa A0A287A3G8 R-SSC-204008 https://reactome.org/PathwayBrowser/#/R-SSC-204008 SEC31:SEC13 and v-SNARE recruitment IEA Sus scrofa A0A287A3G8 R-SSC-5694409 https://reactome.org/PathwayBrowser/#/R-SSC-5694409 Nucleotide exchange on RAB1 IEA Sus scrofa A0A287A3G8 R-SSC-5694418 https://reactome.org/PathwayBrowser/#/R-SSC-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Sus scrofa A0A287A3G8 R-SSC-5694423 https://reactome.org/PathwayBrowser/#/R-SSC-5694423 NSF and SNAPs bind cis-SNARE complex IEA Sus scrofa A0A287A3G8 R-SSC-5694425 https://reactome.org/PathwayBrowser/#/R-SSC-5694425 NSF ATPase activity dissociates cis-SNARE IEA Sus scrofa A0A287A3G8 R-SSC-5694446 https://reactome.org/PathwayBrowser/#/R-SSC-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Sus scrofa A0A287A3H2 R-SSC-111437 https://reactome.org/PathwayBrowser/#/R-SSC-111437 Cleavage of the 3'-end of the Histone Pre-mRNA IEA Sus scrofa A0A287A3H2 R-SSC-111438 https://reactome.org/PathwayBrowser/#/R-SSC-111438 Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA IEA Sus scrofa A0A287A3H2 R-SSC-77585 https://reactome.org/PathwayBrowser/#/R-SSC-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA IEA Sus scrofa A0A287A3H2 R-SSC-77586 https://reactome.org/PathwayBrowser/#/R-SSC-77586 Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA IEA Sus scrofa A0A287A3I4 R-SSC-77609 https://reactome.org/PathwayBrowser/#/R-SSC-77609 Binding of APOBEC-1 to form editosome IEA Sus scrofa A0A287A3I4 R-SSC-83677 https://reactome.org/PathwayBrowser/#/R-SSC-83677 C4 deamination of cytidine IEA Sus scrofa A0A287A3J4 R-SSC-5362412 https://reactome.org/PathwayBrowser/#/R-SSC-5362412 SYVN1 ubiquitinates Hh C-terminal fragments IEA Sus scrofa A0A287A3J4 R-SSC-5362441 https://reactome.org/PathwayBrowser/#/R-SSC-5362441 C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane IEA Sus scrofa A0A287A3J4 R-SSC-5362459 https://reactome.org/PathwayBrowser/#/R-SSC-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Sus scrofa A0A287A3J4 R-SSC-8866542 https://reactome.org/PathwayBrowser/#/R-SSC-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Sus scrofa A0A287A3J4 R-SSC-8866546 https://reactome.org/PathwayBrowser/#/R-SSC-8866546 RNF5 and RNF185 ubiquitinate misfolded CFTR IEA Sus scrofa A0A287A3J4 R-SSC-8866551 https://reactome.org/PathwayBrowser/#/R-SSC-8866551 CFTR binds components of the ERAD machinery for ubiquitination and degradation IEA Sus scrofa A0A287A3K3 R-SSC-162730 https://reactome.org/PathwayBrowser/#/R-SSC-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Sus scrofa A0A287A3K5 R-SSC-198746 https://reactome.org/PathwayBrowser/#/R-SSC-198746 ERK1/2/5 activate RSK1/2/3 IEA Sus scrofa A0A287A3K5 R-SSC-199895 https://reactome.org/PathwayBrowser/#/R-SSC-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Sus scrofa A0A287A3K5 R-SSC-442724 https://reactome.org/PathwayBrowser/#/R-SSC-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Sus scrofa A0A287A3K5 R-SSC-9029434 https://reactome.org/PathwayBrowser/#/R-SSC-9029434 p-S363,S380,T573 RS6K translocates to the nucleus IEA Sus scrofa A0A287A3L1 R-SSC-1602368 https://reactome.org/PathwayBrowser/#/R-SSC-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Sus scrofa A0A287A3L1 R-SSC-1602374 https://reactome.org/PathwayBrowser/#/R-SSC-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Sus scrofa A0A287A3L1 R-SSC-1602377 https://reactome.org/PathwayBrowser/#/R-SSC-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Sus scrofa A0A287A3L1 R-SSC-1602398 https://reactome.org/PathwayBrowser/#/R-SSC-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Sus scrofa A0A287A3L1 R-SSC-1602417 https://reactome.org/PathwayBrowser/#/R-SSC-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Sus scrofa A0A287A3L1 R-SSC-1602446 https://reactome.org/PathwayBrowser/#/R-SSC-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Sus scrofa A0A287A3M1 R-SSC-975311 https://reactome.org/PathwayBrowser/#/R-SSC-975311 HTR3 pentamers:5HT transport Na+,K+,Ca2+ IEA Sus scrofa A0A287A3M2 R-SSC-426489 https://reactome.org/PathwayBrowser/#/R-SSC-426489 RISC binds inexactly matching target RNAs IEA Sus scrofa A0A287A3M2 R-SSC-426522 https://reactome.org/PathwayBrowser/#/R-SSC-426522 Nonendonucleolytic RISC binds exactly matching target RNAs IEA Sus scrofa A0A287A3Q1 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa A0A287A3Q1 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287A3Q1 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287A3Q1 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287A3Q1 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa A0A287A3Q5 R-SSC-9825759 https://reactome.org/PathwayBrowser/#/R-SSC-9825759 MAPK-dependent phosphorylation of KARS IEA Sus scrofa A0A287A3Q5 R-SSC-9825782 https://reactome.org/PathwayBrowser/#/R-SSC-9825782 p-S207 KARS1 dimer binds MITF-M:HINT1 dimer IEA Sus scrofa A0A287A3Q5 R-SSC-9825783 https://reactome.org/PathwayBrowser/#/R-SSC-9825783 p-S207 KARS1 dimer translocates to the nucleus IEA Sus scrofa A0A287A3Q5 R-SSC-9825788 https://reactome.org/PathwayBrowser/#/R-SSC-9825788 p-S207 KARS displaces HINT1 IEA Sus scrofa A0A287A3Q5 R-SSC-9825790 https://reactome.org/PathwayBrowser/#/R-SSC-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Sus scrofa A0A287A3R9 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287A3T1 R-SSC-446634 https://reactome.org/PathwayBrowser/#/R-SSC-446634 IRAK4 is activated by autophosphorylation IEA Sus scrofa A0A287A3T1 R-SSC-446684 https://reactome.org/PathwayBrowser/#/R-SSC-446684 IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation IEA Sus scrofa A0A287A3T1 R-SSC-446692 https://reactome.org/PathwayBrowser/#/R-SSC-446692 IRAK1 binds to MYD88 within the IL1R complex IEA Sus scrofa A0A287A3T1 R-SSC-446694 https://reactome.org/PathwayBrowser/#/R-SSC-446694 IRAK4 phosphorylates IRAK1 IEA Sus scrofa A0A287A3T1 R-SSC-446701 https://reactome.org/PathwayBrowser/#/R-SSC-446701 IRAK4-activated IRAK1 autophosphorylates IEA Sus scrofa A0A287A3T1 R-SSC-446862 https://reactome.org/PathwayBrowser/#/R-SSC-446862 Hyperphosphorylated IRAK1 associates with TRAF6 IEA Sus scrofa A0A287A3T1 R-SSC-446868 https://reactome.org/PathwayBrowser/#/R-SSC-446868 The Interleukin 1 receptor complex binds Tollip IEA Sus scrofa A0A287A3T1 R-SSC-446894 https://reactome.org/PathwayBrowser/#/R-SSC-446894 TRAF6 binding leads to IRAK1:TRAF6 release IEA Sus scrofa A0A287A3T1 R-SSC-6798749 https://reactome.org/PathwayBrowser/#/R-SSC-6798749 Exocytosis of specific granule lumen proteins IEA Sus scrofa A0A287A3T1 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A287A3T3 R-SSC-8854222 https://reactome.org/PathwayBrowser/#/R-SSC-8854222 TBC1D3 associates with RAB5 IEA Sus scrofa A0A287A3T6 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287A3T6 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287A3T6 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287A3T6 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287A3T6 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287A3T6 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287A3T6 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287A3T6 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287A3T6 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287A3T6 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287A3T6 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287A3T6 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287A3T6 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287A3T6 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287A3T6 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287A3T6 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287A3T6 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287A3T6 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287A3T6 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287A3T6 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287A3T6 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287A3T6 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287A3T6 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287A3T6 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287A3T6 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287A3T6 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287A3T6 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287A3T6 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287A3T6 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287A3T6 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287A3T6 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287A3T6 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287A3T6 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287A3T6 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287A3T6 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287A3T6 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287A3T6 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287A3T6 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287A3T6 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287A3T6 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287A3T6 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287A3T6 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287A3T6 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287A3T6 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287A3T6 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287A3T6 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287A3T6 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287A3U2 R-SSC-390427 https://reactome.org/PathwayBrowser/#/R-SSC-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate IEA Sus scrofa A0A287A3U2 R-SSC-75879 https://reactome.org/PathwayBrowser/#/R-SSC-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH IEA Sus scrofa A0A287A3U2 R-SSC-9033232 https://reactome.org/PathwayBrowser/#/R-SSC-9033232 PEX7 binds cargo proteins containing PTS2 IEA Sus scrofa A0A287A3U2 R-SSC-9033514 https://reactome.org/PathwayBrowser/#/R-SSC-9033514 Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A287A3U3 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A287A3U3 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287A3U3 R-SSC-76590 https://reactome.org/PathwayBrowser/#/R-SSC-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Sus scrofa A0A287A3U4 R-SSC-2684901 https://reactome.org/PathwayBrowser/#/R-SSC-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Sus scrofa A0A287A3V0 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287A3V7 R-SSC-4724284 https://reactome.org/PathwayBrowser/#/R-SSC-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Sus scrofa A0A287A3V7 R-SSC-5661115 https://reactome.org/PathwayBrowser/#/R-SSC-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Sus scrofa A0A287A3W3 R-SSC-6783955 https://reactome.org/PathwayBrowser/#/R-SSC-6783955 PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa A0A287A3W6 R-SSC-8952638 https://reactome.org/PathwayBrowser/#/R-SSC-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A3W6 R-SSC-8955245 https://reactome.org/PathwayBrowser/#/R-SSC-8955245 CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus IEA Sus scrofa A0A287A3W6 R-SSC-8955285 https://reactome.org/PathwayBrowser/#/R-SSC-8955285 COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A3W6 R-SSC-8956045 https://reactome.org/PathwayBrowser/#/R-SSC-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A3X6 R-SSC-1168644 https://reactome.org/PathwayBrowser/#/R-SSC-1168644 CARMA1 recruits MALT1 and BCL10 forming CBM Complex IEA Sus scrofa A0A287A3X6 R-SSC-202394 https://reactome.org/PathwayBrowser/#/R-SSC-202394 Translocation of CARMA1 to Plasma membrane IEA Sus scrofa A0A287A3X6 R-SSC-202437 https://reactome.org/PathwayBrowser/#/R-SSC-202437 Phosphorylation of CARMA1 IEA Sus scrofa A0A287A3X6 R-SSC-202443 https://reactome.org/PathwayBrowser/#/R-SSC-202443 Oligomerization of CARMA1 IEA Sus scrofa A0A287A3X6 R-SSC-202453 https://reactome.org/PathwayBrowser/#/R-SSC-202453 Auto-ubiquitination of TRAF6 IEA Sus scrofa A0A287A3X6 R-SSC-202459 https://reactome.org/PathwayBrowser/#/R-SSC-202459 Phosphorylation of Bcl10 IEA Sus scrofa A0A287A3X6 R-SSC-202466 https://reactome.org/PathwayBrowser/#/R-SSC-202466 Interaction of Bcl10 to CARMA1 IEA Sus scrofa A0A287A3X6 R-SSC-202472 https://reactome.org/PathwayBrowser/#/R-SSC-202472 Translocation of TRAF6 to CBM complex IEA Sus scrofa A0A287A3X6 R-SSC-202478 https://reactome.org/PathwayBrowser/#/R-SSC-202478 Interaction and oligomerization of MALT1 to Bcl10 IEA Sus scrofa A0A287A3X6 R-SSC-202489 https://reactome.org/PathwayBrowser/#/R-SSC-202489 Oligomerization of Bcl10 IEA Sus scrofa A0A287A3X6 R-SSC-202500 https://reactome.org/PathwayBrowser/#/R-SSC-202500 Activation of IKK complex IEA Sus scrofa A0A287A3X6 R-SSC-202510 https://reactome.org/PathwayBrowser/#/R-SSC-202510 Activation of TAK1-TAB2 complex IEA Sus scrofa A0A287A3X6 R-SSC-202534 https://reactome.org/PathwayBrowser/#/R-SSC-202534 Ubiquitination of NEMO by TRAF6 IEA Sus scrofa A0A287A3X6 R-SSC-2730861 https://reactome.org/PathwayBrowser/#/R-SSC-2730861 Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 IEA Sus scrofa A0A287A3X6 R-SSC-2730863 https://reactome.org/PathwayBrowser/#/R-SSC-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Sus scrofa A0A287A3X6 R-SSC-2730864 https://reactome.org/PathwayBrowser/#/R-SSC-2730864 Recruitment of TRAF6 to CBM complex by binding to MALT1 IEA Sus scrofa A0A287A3X6 R-SSC-2730876 https://reactome.org/PathwayBrowser/#/R-SSC-2730876 Phosphorylation of IKK-beta by TAK1 IEA Sus scrofa A0A287A3X6 R-SSC-2730899 https://reactome.org/PathwayBrowser/#/R-SSC-2730899 Oligomerization of BCL10 and MALT1 IEA Sus scrofa A0A287A3X6 R-SSC-2730900 https://reactome.org/PathwayBrowser/#/R-SSC-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Sus scrofa A0A287A3X6 R-SSC-2730902 https://reactome.org/PathwayBrowser/#/R-SSC-2730902 Oligomerization of p-CARMA1 IEA Sus scrofa A0A287A3X6 R-SSC-2730903 https://reactome.org/PathwayBrowser/#/R-SSC-2730903 Oligomerization of TRAF6 IEA Sus scrofa A0A287A3X6 R-SSC-2730904 https://reactome.org/PathwayBrowser/#/R-SSC-2730904 Auto-ubiquitination of TRAF6 IEA Sus scrofa A0A287A3X9 R-SSC-71802 https://reactome.org/PathwayBrowser/#/R-SSC-71802 PFKFKB dimer phosphorylates Fru(6)P IEA Sus scrofa A0A287A3Y0 R-SSC-212352 https://reactome.org/PathwayBrowser/#/R-SSC-212352 Formation of ARC coactivator complex IEA Sus scrofa A0A287A3Y0 R-SSC-212380 https://reactome.org/PathwayBrowser/#/R-SSC-212380 Formation of TRAP coactivator complex IEA Sus scrofa A0A287A3Y0 R-SSC-212432 https://reactome.org/PathwayBrowser/#/R-SSC-212432 Formation of DRIP coactivator complex IEA Sus scrofa A0A287A3Y0 R-SSC-2176475 https://reactome.org/PathwayBrowser/#/R-SSC-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Sus scrofa A0A287A3Y0 R-SSC-9843120 https://reactome.org/PathwayBrowser/#/R-SSC-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Sus scrofa A0A287A3Z7 R-SSC-5653754 https://reactome.org/PathwayBrowser/#/R-SSC-5653754 UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA IEA Sus scrofa A0A287A3Z7 R-SSC-5653756 https://reactome.org/PathwayBrowser/#/R-SSC-5653756 TRIM25 binds monoUb:164-PCNA IEA Sus scrofa A0A287A3Z7 R-SSC-5653766 https://reactome.org/PathwayBrowser/#/R-SSC-5653766 USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A287A3Z7 R-SSC-5653770 https://reactome.org/PathwayBrowser/#/R-SSC-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A287A3Z7 R-SSC-5656105 https://reactome.org/PathwayBrowser/#/R-SSC-5656105 POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA IEA Sus scrofa A0A287A3Z7 R-SSC-5656148 https://reactome.org/PathwayBrowser/#/R-SSC-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Sus scrofa A0A287A3Z7 R-SSC-5656158 https://reactome.org/PathwayBrowser/#/R-SSC-5656158 POLZ elongates POLI-incorporated dNMP IEA Sus scrofa A0A287A412 R-SSC-6791109 https://reactome.org/PathwayBrowser/#/R-SSC-6791109 GADD45A binds PCNA IEA Sus scrofa A0A287A412 R-SSC-6791235 https://reactome.org/PathwayBrowser/#/R-SSC-6791235 GADD45A binds AURKA IEA Sus scrofa A0A287A440 R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa A0A287A440 R-SSC-9709406 https://reactome.org/PathwayBrowser/#/R-SSC-9709406 CO binds to Cytochrome c oxidase IEA Sus scrofa A0A287A440 R-SSC-9865412 https://reactome.org/PathwayBrowser/#/R-SSC-9865412 TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC IEA Sus scrofa A0A287A440 R-SSC-9865449 https://reactome.org/PathwayBrowser/#/R-SSC-9865449 Metallochaperone inserts Cu2+ into MT-CO1 IEA Sus scrofa A0A287A440 R-SSC-9865579 https://reactome.org/PathwayBrowser/#/R-SSC-9865579 MT-CO1 and MT-CO2 complexes associate, installing heme moieties IEA Sus scrofa A0A287A440 R-SSC-9865663 https://reactome.org/PathwayBrowser/#/R-SSC-9865663 MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex IEA Sus scrofa A0A287A463 R-SSC-2993447 https://reactome.org/PathwayBrowser/#/R-SSC-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Sus scrofa A0A287A463 R-SSC-2993799 https://reactome.org/PathwayBrowser/#/R-SSC-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Sus scrofa A0A287A463 R-SSC-2993802 https://reactome.org/PathwayBrowser/#/R-SSC-2993802 HLCS biotinylates PC:Mn2+ IEA Sus scrofa A0A287A463 R-SSC-2993814 https://reactome.org/PathwayBrowser/#/R-SSC-2993814 HLCS biotinylates ACACA:Mn2+ IEA Sus scrofa A0A287A463 R-SSC-4167511 https://reactome.org/PathwayBrowser/#/R-SSC-4167511 HLCS biotinylates ACACB IEA Sus scrofa A0A287A496 R-SSC-8857692 https://reactome.org/PathwayBrowser/#/R-SSC-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Sus scrofa A0A287A498 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A498 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287A498 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A498 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A498 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A498 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287A498 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287A498 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287A498 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287A4B4 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A287A4B4 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A287A4B4 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A287A4B4 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A287A4B4 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287A4B4 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287A4B4 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287A4B4 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287A4B4 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287A4B4 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287A4B4 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A287A4B4 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A287A4B4 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A287A4B4 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A287A4B4 R-SSC-606287 https://reactome.org/PathwayBrowser/#/R-SSC-606287 RSF complex binds the centromere IEA Sus scrofa A0A287A4B4 R-SSC-606326 https://reactome.org/PathwayBrowser/#/R-SSC-606326 HJURP:CENPA complex localizes to the centromere IEA Sus scrofa A0A287A4B4 R-SSC-606349 https://reactome.org/PathwayBrowser/#/R-SSC-606349 Mis18 complex binds the centromere IEA Sus scrofa A0A287A4B4 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287A4E4 R-SSC-112379 https://reactome.org/PathwayBrowser/#/R-SSC-112379 Recruitment of elongation factors to form elongation complex IEA Sus scrofa A0A287A4E4 R-SSC-112381 https://reactome.org/PathwayBrowser/#/R-SSC-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Sus scrofa A0A287A4E4 R-SSC-112385 https://reactome.org/PathwayBrowser/#/R-SSC-112385 Addition of nucleotides leads to transcript elongation IEA Sus scrofa A0A287A4E4 R-SSC-112392 https://reactome.org/PathwayBrowser/#/R-SSC-112392 Resumption of elongation after recovery from pausing IEA Sus scrofa A0A287A4E4 R-SSC-112395 https://reactome.org/PathwayBrowser/#/R-SSC-112395 Abortive termination of elongation after arrest IEA Sus scrofa A0A287A4E4 R-SSC-112396 https://reactome.org/PathwayBrowser/#/R-SSC-112396 Separation of elongating transcript from template IEA Sus scrofa A0A287A4E4 R-SSC-113411 https://reactome.org/PathwayBrowser/#/R-SSC-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Sus scrofa A0A287A4E4 R-SSC-113412 https://reactome.org/PathwayBrowser/#/R-SSC-113412 Pol II elongation complex moves on the template as transcript elongates IEA Sus scrofa A0A287A4E4 R-SSC-113413 https://reactome.org/PathwayBrowser/#/R-SSC-113413 TFIIS-mediated recovery of elongation from arrest IEA Sus scrofa A0A287A4E4 R-SSC-113414 https://reactome.org/PathwayBrowser/#/R-SSC-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Sus scrofa A0A287A4E4 R-SSC-113429 https://reactome.org/PathwayBrowser/#/R-SSC-113429 Elongating transcript encounters a lesion in the template IEA Sus scrofa A0A287A4F0 R-SSC-1675773 https://reactome.org/PathwayBrowser/#/R-SSC-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Sus scrofa A0A287A4F0 R-SSC-1675810 https://reactome.org/PathwayBrowser/#/R-SSC-1675810 PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane IEA Sus scrofa A0A287A4F0 R-SSC-1676082 https://reactome.org/PathwayBrowser/#/R-SSC-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Sus scrofa A0A287A4F0 R-SSC-1676134 https://reactome.org/PathwayBrowser/#/R-SSC-1676134 PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane IEA Sus scrofa A0A287A4F0 R-SSC-1676145 https://reactome.org/PathwayBrowser/#/R-SSC-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Sus scrofa A0A287A4F2 R-SSC-8849463 https://reactome.org/PathwayBrowser/#/R-SSC-8849463 PTK6 phosphorylates SFPQ IEA Sus scrofa A0A287A4G2 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A287A4G2 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A287A4G2 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A287A4G2 R-SSC-6800426 https://reactome.org/PathwayBrowser/#/R-SSC-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Sus scrofa A0A287A4G3 R-SSC-6794346 https://reactome.org/PathwayBrowser/#/R-SSC-6794346 NRXNs bind NLGNs IEA Sus scrofa A0A287A4G3 R-SSC-6797554 https://reactome.org/PathwayBrowser/#/R-SSC-6797554 ABP1 binds SHANK proteins IEA Sus scrofa A0A287A4G3 R-SSC-6797568 https://reactome.org/PathwayBrowser/#/R-SSC-6797568 NRXNs bind CASK:Protein 4.1 IEA Sus scrofa A0A287A4G3 R-SSC-6797974 https://reactome.org/PathwayBrowser/#/R-SSC-6797974 LRRTMs bind NRXNs IEA Sus scrofa A0A287A4M5 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287A4M8 R-SSC-936897 https://reactome.org/PathwayBrowser/#/R-SSC-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Sus scrofa A0A287A4M8 R-SSC-9684068 https://reactome.org/PathwayBrowser/#/R-SSC-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Sus scrofa A0A287A4M9 R-SSC-195283 https://reactome.org/PathwayBrowser/#/R-SSC-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Sus scrofa A0A287A4M9 R-SSC-195287 https://reactome.org/PathwayBrowser/#/R-SSC-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Sus scrofa A0A287A4M9 R-SSC-195300 https://reactome.org/PathwayBrowser/#/R-SSC-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Sus scrofa A0A287A4M9 R-SSC-5323526 https://reactome.org/PathwayBrowser/#/R-SSC-5323526 FRAT proteins bind GSK3beta IEA Sus scrofa A0A287A4T1 R-SSC-8854588 https://reactome.org/PathwayBrowser/#/R-SSC-8854588 TBC1D25 (OATL1) binds ATG8 homologues IEA Sus scrofa A0A287A4T1 R-SSC-8854612 https://reactome.org/PathwayBrowser/#/R-SSC-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Sus scrofa A0A287A4V7 R-SSC-5336453 https://reactome.org/PathwayBrowser/#/R-SSC-5336453 NIPAs transport Mg2+ from extracellular region to cytosol IEA Sus scrofa A0A287A4W2 R-SSC-112379 https://reactome.org/PathwayBrowser/#/R-SSC-112379 Recruitment of elongation factors to form elongation complex IEA Sus scrofa A0A287A4W2 R-SSC-112381 https://reactome.org/PathwayBrowser/#/R-SSC-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Sus scrofa A0A287A4W2 R-SSC-112385 https://reactome.org/PathwayBrowser/#/R-SSC-112385 Addition of nucleotides leads to transcript elongation IEA Sus scrofa A0A287A4W2 R-SSC-112392 https://reactome.org/PathwayBrowser/#/R-SSC-112392 Resumption of elongation after recovery from pausing IEA Sus scrofa A0A287A4W2 R-SSC-112395 https://reactome.org/PathwayBrowser/#/R-SSC-112395 Abortive termination of elongation after arrest IEA Sus scrofa A0A287A4W2 R-SSC-112396 https://reactome.org/PathwayBrowser/#/R-SSC-112396 Separation of elongating transcript from template IEA Sus scrofa A0A287A4W2 R-SSC-113411 https://reactome.org/PathwayBrowser/#/R-SSC-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Sus scrofa A0A287A4W2 R-SSC-113412 https://reactome.org/PathwayBrowser/#/R-SSC-113412 Pol II elongation complex moves on the template as transcript elongates IEA Sus scrofa A0A287A4W2 R-SSC-113413 https://reactome.org/PathwayBrowser/#/R-SSC-113413 TFIIS-mediated recovery of elongation from arrest IEA Sus scrofa A0A287A4W2 R-SSC-113414 https://reactome.org/PathwayBrowser/#/R-SSC-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Sus scrofa A0A287A4W2 R-SSC-113429 https://reactome.org/PathwayBrowser/#/R-SSC-113429 Elongating transcript encounters a lesion in the template IEA Sus scrofa A0A287A4W2 R-SSC-6797606 https://reactome.org/PathwayBrowser/#/R-SSC-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Sus scrofa A0A287A4W2 R-SSC-6797616 https://reactome.org/PathwayBrowser/#/R-SSC-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Sus scrofa A0A287A4W2 R-SSC-6814549 https://reactome.org/PathwayBrowser/#/R-SSC-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Sus scrofa A0A287A4W2 R-SSC-6814555 https://reactome.org/PathwayBrowser/#/R-SSC-6814555 Integrator complex processes the 3' end of snRNA IEA Sus scrofa A0A287A4W2 R-SSC-6814559 https://reactome.org/PathwayBrowser/#/R-SSC-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Sus scrofa A0A287A4W2 R-SSC-6814885 https://reactome.org/PathwayBrowser/#/R-SSC-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Sus scrofa A0A287A4Z2 R-SSC-3299680 https://reactome.org/PathwayBrowser/#/R-SSC-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Sus scrofa A0A287A4Z2 R-SSC-5688289 https://reactome.org/PathwayBrowser/#/R-SSC-5688289 SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 IEA Sus scrofa A0A287A4Z4 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287A4Z4 R-SSC-419426 https://reactome.org/PathwayBrowser/#/R-SSC-419426 Cannabinoid receptors can bind cannabinoids IEA Sus scrofa A0A287A4Z4 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287A4Z4 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287A4Z4 R-SSC-9696323 https://reactome.org/PathwayBrowser/#/R-SSC-9696323 CNRs bind CNR agonists IEA Sus scrofa A0A287A519 R-SSC-183036 https://reactome.org/PathwayBrowser/#/R-SSC-183036 Ubiquitination of stimulated EGFR (CBL:GRB2) IEA Sus scrofa A0A287A520 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287A524 R-SSC-1638032 https://reactome.org/PathwayBrowser/#/R-SSC-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Sus scrofa A0A287A524 R-SSC-432706 https://reactome.org/PathwayBrowser/#/R-SSC-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Sus scrofa A0A287A524 R-SSC-432707 https://reactome.org/PathwayBrowser/#/R-SSC-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Sus scrofa A0A287A524 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A287A524 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287A537 R-SSC-2046285 https://reactome.org/PathwayBrowser/#/R-SSC-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Sus scrofa A0A287A537 R-SSC-4084984 https://reactome.org/PathwayBrowser/#/R-SSC-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Sus scrofa A0A287A537 R-SSC-981497 https://reactome.org/PathwayBrowser/#/R-SSC-981497 ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position IEA Sus scrofa A0A287A537 R-SSC-9845538 https://reactome.org/PathwayBrowser/#/R-SSC-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Sus scrofa A0A287A543 R-SSC-2671885 https://reactome.org/PathwayBrowser/#/R-SSC-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Sus scrofa A0A287A543 R-SSC-8863494 https://reactome.org/PathwayBrowser/#/R-SSC-8863494 ASICs bind STOML3, (STOM) IEA Sus scrofa A0A287A543 R-SSC-9650165 https://reactome.org/PathwayBrowser/#/R-SSC-9650165 ASIC trimers bind H+ IEA Sus scrofa A0A287A546 R-SSC-5658231 https://reactome.org/PathwayBrowser/#/R-SSC-5658231 RAS GAPs stimulate RAS GTPase activity IEA Sus scrofa A0A287A546 R-SSC-5658435 https://reactome.org/PathwayBrowser/#/R-SSC-5658435 RAS GAPs bind RAS:GTP IEA Sus scrofa A0A287A551 R-SSC-975916 https://reactome.org/PathwayBrowser/#/R-SSC-975916 Addition of GlcNAc to position 5 by MGAT5 IEA Sus scrofa A0A287A561 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A287A561 R-SSC-5672083 https://reactome.org/PathwayBrowser/#/R-SSC-5672083 KTN1 binds Kinesin-1 IEA Sus scrofa A0A287A561 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa A0A287A561 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa A0A287A561 R-SSC-983194 https://reactome.org/PathwayBrowser/#/R-SSC-983194 Kinesin-1 is a heterotetramer IEA Sus scrofa A0A287A561 R-SSC-983259 https://reactome.org/PathwayBrowser/#/R-SSC-983259 Kinesins move along microtubules consuming ATP IEA Sus scrofa A0A287A561 R-SSC-983266 https://reactome.org/PathwayBrowser/#/R-SSC-983266 Kinesins bind microtubules IEA Sus scrofa A0A287A564 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287A565 R-SSC-6794346 https://reactome.org/PathwayBrowser/#/R-SSC-6794346 NRXNs bind NLGNs IEA Sus scrofa A0A287A565 R-SSC-6797554 https://reactome.org/PathwayBrowser/#/R-SSC-6797554 ABP1 binds SHANK proteins IEA Sus scrofa A0A287A565 R-SSC-6797568 https://reactome.org/PathwayBrowser/#/R-SSC-6797568 NRXNs bind CASK:Protein 4.1 IEA Sus scrofa A0A287A598 R-SSC-77609 https://reactome.org/PathwayBrowser/#/R-SSC-77609 Binding of APOBEC-1 to form editosome IEA Sus scrofa A0A287A598 R-SSC-83677 https://reactome.org/PathwayBrowser/#/R-SSC-83677 C4 deamination of cytidine IEA Sus scrofa A0A287A5D3 R-SSC-374787 https://reactome.org/PathwayBrowser/#/R-SSC-374787 GPCR neuropeptide receptor binds neuropeptides B and W IEA Sus scrofa A0A287A5D3 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287A5D3 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287A5D3 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287A5E9 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa A0A287A5E9 R-SSC-418925 https://reactome.org/PathwayBrowser/#/R-SSC-418925 ADORA2A,B bind Ade-Rib IEA Sus scrofa A0A287A5E9 R-SSC-5684862 https://reactome.org/PathwayBrowser/#/R-SSC-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region IEA Sus scrofa A0A287A5G3 R-SSC-3247837 https://reactome.org/PathwayBrowser/#/R-SSC-3247837 WNT ligands traffic to the Golgi IEA Sus scrofa A0A287A5G9 R-SSC-77608 https://reactome.org/PathwayBrowser/#/R-SSC-77608 Binding of A1CF to stem-looped RNA IEA Sus scrofa A0A287A5G9 R-SSC-77609 https://reactome.org/PathwayBrowser/#/R-SSC-77609 Binding of APOBEC-1 to form editosome IEA Sus scrofa A0A287A5G9 R-SSC-83677 https://reactome.org/PathwayBrowser/#/R-SSC-83677 C4 deamination of cytidine IEA Sus scrofa A0A287A5I9 R-SSC-2106614 https://reactome.org/PathwayBrowser/#/R-SSC-2106614 Duplex miRNA is loaded into Argonaute IEA Sus scrofa A0A287A5I9 R-SSC-2106615 https://reactome.org/PathwayBrowser/#/R-SSC-2106615 Removal of siRNA passenger strand IEA Sus scrofa A0A287A5I9 R-SSC-2106625 https://reactome.org/PathwayBrowser/#/R-SSC-2106625 Duplex siRNA is loaded into Argonaute IEA Sus scrofa A0A287A5I9 R-SSC-210805 https://reactome.org/PathwayBrowser/#/R-SSC-210805 Removal of miRNA passenger strand IEA Sus scrofa A0A287A5I9 R-SSC-426464 https://reactome.org/PathwayBrowser/#/R-SSC-426464 Dicer cleaves double-stranded RNA to yield double-stranded siRNA IEA Sus scrofa A0A287A5I9 R-SSC-9834821 https://reactome.org/PathwayBrowser/#/R-SSC-9834821 p-PRKRA dimer binds PKR IEA Sus scrofa A0A287A5K0 R-SSC-1013012 https://reactome.org/PathwayBrowser/#/R-SSC-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Sus scrofa A0A287A5K0 R-SSC-1013020 https://reactome.org/PathwayBrowser/#/R-SSC-1013020 Activation of GIRK/Kir3 Channels IEA Sus scrofa A0A287A5K0 R-SSC-1296046 https://reactome.org/PathwayBrowser/#/R-SSC-1296046 KCNJs transport K+ from the extracellular region to cytosol IEA Sus scrofa A0A287A5K5 R-SSC-109639 https://reactome.org/PathwayBrowser/#/R-SSC-109639 Formation of the closed pre-initiation complex IEA Sus scrofa A0A287A5K5 R-SSC-111264 https://reactome.org/PathwayBrowser/#/R-SSC-111264 Addition of nucleotides between position +11 and +30 IEA Sus scrofa A0A287A5K5 R-SSC-112379 https://reactome.org/PathwayBrowser/#/R-SSC-112379 Recruitment of elongation factors to form elongation complex IEA Sus scrofa A0A287A5K5 R-SSC-112383 https://reactome.org/PathwayBrowser/#/R-SSC-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Sus scrofa A0A287A5K5 R-SSC-112385 https://reactome.org/PathwayBrowser/#/R-SSC-112385 Addition of nucleotides leads to transcript elongation IEA Sus scrofa A0A287A5K5 R-SSC-113430 https://reactome.org/PathwayBrowser/#/R-SSC-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Sus scrofa A0A287A5K5 R-SSC-5689317 https://reactome.org/PathwayBrowser/#/R-SSC-5689317 Formation of the pre-incision complex in GG-NER IEA Sus scrofa A0A287A5K5 R-SSC-5689861 https://reactome.org/PathwayBrowser/#/R-SSC-5689861 Recruitment of XPA and release of CAK IEA Sus scrofa A0A287A5K5 R-SSC-5690213 https://reactome.org/PathwayBrowser/#/R-SSC-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Sus scrofa A0A287A5K5 R-SSC-5690988 https://reactome.org/PathwayBrowser/#/R-SSC-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Sus scrofa A0A287A5K5 R-SSC-5690990 https://reactome.org/PathwayBrowser/#/R-SSC-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Sus scrofa A0A287A5K5 R-SSC-5690991 https://reactome.org/PathwayBrowser/#/R-SSC-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER IEA Sus scrofa A0A287A5K5 R-SSC-5690996 https://reactome.org/PathwayBrowser/#/R-SSC-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Sus scrofa A0A287A5K5 R-SSC-5691000 https://reactome.org/PathwayBrowser/#/R-SSC-5691000 TFIIH binds GG-NER site to form a verification complex IEA Sus scrofa A0A287A5K5 R-SSC-5696670 https://reactome.org/PathwayBrowser/#/R-SSC-5696670 CHD1L is recruited to GG-NER site IEA Sus scrofa A0A287A5K5 R-SSC-6781818 https://reactome.org/PathwayBrowser/#/R-SSC-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Sus scrofa A0A287A5K5 R-SSC-6781824 https://reactome.org/PathwayBrowser/#/R-SSC-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Sus scrofa A0A287A5K5 R-SSC-6781833 https://reactome.org/PathwayBrowser/#/R-SSC-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Sus scrofa A0A287A5K5 R-SSC-6781867 https://reactome.org/PathwayBrowser/#/R-SSC-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Sus scrofa A0A287A5K5 R-SSC-6782004 https://reactome.org/PathwayBrowser/#/R-SSC-6782004 Assembly of the pre-incision complex in TC-NER IEA Sus scrofa A0A287A5K5 R-SSC-6782069 https://reactome.org/PathwayBrowser/#/R-SSC-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Sus scrofa A0A287A5K5 R-SSC-6782131 https://reactome.org/PathwayBrowser/#/R-SSC-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa A0A287A5K5 R-SSC-6782138 https://reactome.org/PathwayBrowser/#/R-SSC-6782138 ERCC5 and RPA bind TC-NER site IEA Sus scrofa A0A287A5K5 R-SSC-6782141 https://reactome.org/PathwayBrowser/#/R-SSC-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Sus scrofa A0A287A5K5 R-SSC-6782204 https://reactome.org/PathwayBrowser/#/R-SSC-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Sus scrofa A0A287A5K5 R-SSC-6782208 https://reactome.org/PathwayBrowser/#/R-SSC-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Sus scrofa A0A287A5K5 R-SSC-6782211 https://reactome.org/PathwayBrowser/#/R-SSC-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Sus scrofa A0A287A5K5 R-SSC-6782224 https://reactome.org/PathwayBrowser/#/R-SSC-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Sus scrofa A0A287A5K5 R-SSC-6782227 https://reactome.org/PathwayBrowser/#/R-SSC-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Sus scrofa A0A287A5K5 R-SSC-6790454 https://reactome.org/PathwayBrowser/#/R-SSC-6790454 SUMOylation of XPC IEA Sus scrofa A0A287A5K5 R-SSC-6797606 https://reactome.org/PathwayBrowser/#/R-SSC-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Sus scrofa A0A287A5K5 R-SSC-6797616 https://reactome.org/PathwayBrowser/#/R-SSC-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Sus scrofa A0A287A5K5 R-SSC-73758 https://reactome.org/PathwayBrowser/#/R-SSC-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Sus scrofa A0A287A5K5 R-SSC-73769 https://reactome.org/PathwayBrowser/#/R-SSC-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Sus scrofa A0A287A5K5 R-SSC-73946 https://reactome.org/PathwayBrowser/#/R-SSC-73946 Abortive initiation after formation of the first phosphodiester bond IEA Sus scrofa A0A287A5K5 R-SSC-74986 https://reactome.org/PathwayBrowser/#/R-SSC-74986 Elongation of pre-rRNA transcript IEA Sus scrofa A0A287A5K5 R-SSC-74993 https://reactome.org/PathwayBrowser/#/R-SSC-74993 PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box IEA Sus scrofa A0A287A5K5 R-SSC-75850 https://reactome.org/PathwayBrowser/#/R-SSC-75850 Addition of the third nucleotide on the nascent transcript IEA Sus scrofa A0A287A5K5 R-SSC-75856 https://reactome.org/PathwayBrowser/#/R-SSC-75856 Abortive Initiation Before Second Transition IEA Sus scrofa A0A287A5K5 R-SSC-75861 https://reactome.org/PathwayBrowser/#/R-SSC-75861 NTP Binds Active Site of RNA Polymerase II IEA Sus scrofa A0A287A5K5 R-SSC-75862 https://reactome.org/PathwayBrowser/#/R-SSC-75862 Fall Back to Closed Pre-initiation Complex IEA Sus scrofa A0A287A5K5 R-SSC-75864 https://reactome.org/PathwayBrowser/#/R-SSC-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Sus scrofa A0A287A5K5 R-SSC-75866 https://reactome.org/PathwayBrowser/#/R-SSC-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Sus scrofa A0A287A5K5 R-SSC-75869 https://reactome.org/PathwayBrowser/#/R-SSC-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Sus scrofa A0A287A5K5 R-SSC-75873 https://reactome.org/PathwayBrowser/#/R-SSC-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Sus scrofa A0A287A5K5 R-SSC-75891 https://reactome.org/PathwayBrowser/#/R-SSC-75891 Abortive Initiation After Second Transition IEA Sus scrofa A0A287A5K5 R-SSC-75949 https://reactome.org/PathwayBrowser/#/R-SSC-75949 RNA Polymerase II Promoter Opening: First Transition IEA Sus scrofa A0A287A5K5 R-SSC-76576 https://reactome.org/PathwayBrowser/#/R-SSC-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Sus scrofa A0A287A5K5 R-SSC-77068 https://reactome.org/PathwayBrowser/#/R-SSC-77068 Activation of GT IEA Sus scrofa A0A287A5K5 R-SSC-77069 https://reactome.org/PathwayBrowser/#/R-SSC-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Sus scrofa A0A287A5K5 R-SSC-77071 https://reactome.org/PathwayBrowser/#/R-SSC-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Sus scrofa A0A287A5K5 R-SSC-77073 https://reactome.org/PathwayBrowser/#/R-SSC-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Sus scrofa A0A287A5K5 R-SSC-77077 https://reactome.org/PathwayBrowser/#/R-SSC-77077 Capping complex formation IEA Sus scrofa A0A287A5K5 R-SSC-77078 https://reactome.org/PathwayBrowser/#/R-SSC-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Sus scrofa A0A287A5K5 R-SSC-77081 https://reactome.org/PathwayBrowser/#/R-SSC-77081 Formation of the CE:GMP intermediate complex IEA Sus scrofa A0A287A5K5 R-SSC-77083 https://reactome.org/PathwayBrowser/#/R-SSC-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Sus scrofa A0A287A5K5 R-SSC-77085 https://reactome.org/PathwayBrowser/#/R-SSC-77085 Dissociation of transcript with 5'-GMP from GT IEA Sus scrofa A0A287A5K5 R-SSC-77090 https://reactome.org/PathwayBrowser/#/R-SSC-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Sus scrofa A0A287A5K5 R-SSC-9613494 https://reactome.org/PathwayBrowser/#/R-SSC-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Sus scrofa A0A287A5K5 R-SSC-9613497 https://reactome.org/PathwayBrowser/#/R-SSC-9613497 Unwinding DNA for the nascent transcript IEA Sus scrofa A0A287A5K5 R-SSC-9684118 https://reactome.org/PathwayBrowser/#/R-SSC-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa A0A287A5L7 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A287A5L7 R-SSC-5624949 https://reactome.org/PathwayBrowser/#/R-SSC-5624949 Assembly of the anterograde IFT train IEA Sus scrofa A0A287A5L7 R-SSC-5624952 https://reactome.org/PathwayBrowser/#/R-SSC-5624952 Assembly of the retrograde IFT train IEA Sus scrofa A0A287A5L7 R-SSC-5625416 https://reactome.org/PathwayBrowser/#/R-SSC-5625416 Anterograde IFT IEA Sus scrofa A0A287A5L7 R-SSC-5625421 https://reactome.org/PathwayBrowser/#/R-SSC-5625421 The anterograde IFT train dissociates IEA Sus scrofa A0A287A5L7 R-SSC-5625424 https://reactome.org/PathwayBrowser/#/R-SSC-5625424 The retrograde IFT train dissociates IEA Sus scrofa A0A287A5L7 R-SSC-5625426 https://reactome.org/PathwayBrowser/#/R-SSC-5625426 Retrograde IFT IEA Sus scrofa A0A287A5L7 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa A0A287A5L7 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa A0A287A5L7 R-SSC-983259 https://reactome.org/PathwayBrowser/#/R-SSC-983259 Kinesins move along microtubules consuming ATP IEA Sus scrofa A0A287A5L7 R-SSC-983266 https://reactome.org/PathwayBrowser/#/R-SSC-983266 Kinesins bind microtubules IEA Sus scrofa A0A287A5N4 R-SSC-8981637 https://reactome.org/PathwayBrowser/#/R-SSC-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Sus scrofa A0A287A5N4 R-SSC-9013144 https://reactome.org/PathwayBrowser/#/R-SSC-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Sus scrofa A0A287A5N6 R-SSC-72180 https://reactome.org/PathwayBrowser/#/R-SSC-72180 Cleavage of mRNA at the 3'-end IEA Sus scrofa A0A287A5N6 R-SSC-72231 https://reactome.org/PathwayBrowser/#/R-SSC-72231 Formation of the Cleavage and Polyadenylation Complex IEA Sus scrofa A0A287A5N6 R-SSC-77591 https://reactome.org/PathwayBrowser/#/R-SSC-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Sus scrofa A0A287A5N6 R-SSC-77592 https://reactome.org/PathwayBrowser/#/R-SSC-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Sus scrofa A0A287A5N6 R-SSC-77593 https://reactome.org/PathwayBrowser/#/R-SSC-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Sus scrofa A0A287A5N6 R-SSC-8849157 https://reactome.org/PathwayBrowser/#/R-SSC-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Sus scrofa A0A287A5Q1 R-SSC-1168638 https://reactome.org/PathwayBrowser/#/R-SSC-1168638 Activated IKK phosphorylates I-kappaB IEA Sus scrofa A0A287A5Q1 R-SSC-168140 https://reactome.org/PathwayBrowser/#/R-SSC-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor IEA Sus scrofa A0A287A5Q1 R-SSC-193641 https://reactome.org/PathwayBrowser/#/R-SSC-193641 IKK-beta is recruited IEA Sus scrofa A0A287A5Q1 R-SSC-193703 https://reactome.org/PathwayBrowser/#/R-SSC-193703 IKKbeta is activated IEA Sus scrofa A0A287A5Q1 R-SSC-193705 https://reactome.org/PathwayBrowser/#/R-SSC-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate IEA Sus scrofa A0A287A5Q1 R-SSC-202500 https://reactome.org/PathwayBrowser/#/R-SSC-202500 Activation of IKK complex IEA Sus scrofa A0A287A5Q1 R-SSC-202534 https://reactome.org/PathwayBrowser/#/R-SSC-202534 Ubiquitination of NEMO by TRAF6 IEA Sus scrofa A0A287A5Q1 R-SSC-202541 https://reactome.org/PathwayBrowser/#/R-SSC-202541 p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB IEA Sus scrofa A0A287A5Q1 R-SSC-209087 https://reactome.org/PathwayBrowser/#/R-SSC-209087 IKBA is phosphorylated by Phospho IKKB kinase IEA Sus scrofa A0A287A5Q1 R-SSC-2730876 https://reactome.org/PathwayBrowser/#/R-SSC-2730876 Phosphorylation of IKK-beta by TAK1 IEA Sus scrofa A0A287A5Q1 R-SSC-451561 https://reactome.org/PathwayBrowser/#/R-SSC-451561 NEMO binds polyubiquitinated IRAK1 IEA Sus scrofa A0A287A5Q1 R-SSC-5357776 https://reactome.org/PathwayBrowser/#/R-SSC-5357776 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG IEA Sus scrofa A0A287A5Q1 R-SSC-5357831 https://reactome.org/PathwayBrowser/#/R-SSC-5357831 CHUK, IKBKB phosphorylate CYLD at S418 IEA Sus scrofa A0A287A5Q1 R-SSC-5607742 https://reactome.org/PathwayBrowser/#/R-SSC-5607742 K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta IEA Sus scrofa A0A287A5Q1 R-SSC-5609665 https://reactome.org/PathwayBrowser/#/R-SSC-5609665 CHUK, IKBKB and IKBKG form IKK complex IEA Sus scrofa A0A287A5Q1 R-SSC-5626962 https://reactome.org/PathwayBrowser/#/R-SSC-5626962 RACK1 binds IKKA:IKKB:NEMO IEA Sus scrofa A0A287A5Q1 R-SSC-5684267 https://reactome.org/PathwayBrowser/#/R-SSC-5684267 IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex IEA Sus scrofa A0A287A5Q1 R-SSC-5684275 https://reactome.org/PathwayBrowser/#/R-SSC-5684275 IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 IEA Sus scrofa A0A287A5Q1 R-SSC-937029 https://reactome.org/PathwayBrowser/#/R-SSC-937029 IKBKG subunit of IKK complex binds polyubiquinated RIP1 IEA Sus scrofa A0A287A5Q1 R-SSC-937032 https://reactome.org/PathwayBrowser/#/R-SSC-937032 NEMO subunit of IKK complex binds to activated IRAK1 IEA Sus scrofa A0A287A5Q1 R-SSC-9749505 https://reactome.org/PathwayBrowser/#/R-SSC-9749505 LRRC14 binds IKBKB and CHUK IEA Sus scrofa A0A287A5Q1 R-SSC-9750226 https://reactome.org/PathwayBrowser/#/R-SSC-9750226 NLRC5 binds IKBKB and CHUK IEA Sus scrofa A0A287A5Q1 R-SSC-9750946 https://reactome.org/PathwayBrowser/#/R-SSC-9750946 TRAF2,6 ubiquitinates NLRC5 IEA Sus scrofa A0A287A5Q1 R-SSC-975119 https://reactome.org/PathwayBrowser/#/R-SSC-975119 NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9 IEA Sus scrofa A0A287A5Q1 R-SSC-9758604 https://reactome.org/PathwayBrowser/#/R-SSC-9758604 Ubiquitination of IKBKG by TRAF6 IEA Sus scrofa A0A287A5Q1 R-SSC-9761344 https://reactome.org/PathwayBrowser/#/R-SSC-9761344 USP18 binds IKBKG within IKK complex IEA Sus scrofa A0A287A5Q1 R-SSC-9773803 https://reactome.org/PathwayBrowser/#/R-SSC-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor IEA Sus scrofa A0A287A5Q1 R-SSC-9818789 https://reactome.org/PathwayBrowser/#/R-SSC-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 IEA Sus scrofa A0A287A5Q1 R-SSC-9836500 https://reactome.org/PathwayBrowser/#/R-SSC-9836500 IKK complex is activated by PKR IEA Sus scrofa A0A287A5Q1 R-SSC-9860292 https://reactome.org/PathwayBrowser/#/R-SSC-9860292 Activated IKBKB phosphorylates IRF5 IEA Sus scrofa A0A287A5Q1 R-SSC-9861486 https://reactome.org/PathwayBrowser/#/R-SSC-9861486 PTK2 (FAK) and Gq/11 enhance the degradation of NFKBIA (IkBalpha), phosphorylation of RELA (p65) on serine-536, and translocation of p-S536-RELA:NFKB1 (p65:p50) to the nucleus IEA Sus scrofa A0A287A5Q1 R-SSC-9909510 https://reactome.org/PathwayBrowser/#/R-SSC-9909510 FKBP5 binds CHUK:IKBKB:IKBKG IEA Sus scrofa A0A287A5Q5 R-SSC-201712 https://reactome.org/PathwayBrowser/#/R-SSC-201712 Beta-catenin:TCF associates with BCL9 and PYGO IEA Sus scrofa A0A287A5Q5 R-SSC-3299569 https://reactome.org/PathwayBrowser/#/R-SSC-3299569 Beta-catenin displaces TLE:HDAC1 from TCF/LEF IEA Sus scrofa A0A287A5Q5 R-SSC-3322422 https://reactome.org/PathwayBrowser/#/R-SSC-3322422 Beta-catenin recruits SMARCA4 IEA Sus scrofa A0A287A5Q5 R-SSC-3322424 https://reactome.org/PathwayBrowser/#/R-SSC-3322424 Beta-catenin recruits CDC73 and LEO1 IEA Sus scrofa A0A287A5Q5 R-SSC-3322427 https://reactome.org/PathwayBrowser/#/R-SSC-3322427 Beta-catenin recruits CBP/p300 IEA Sus scrofa A0A287A5Q5 R-SSC-3361751 https://reactome.org/PathwayBrowser/#/R-SSC-3361751 beta-catenin is replaced by repression complexes at the promoter IEA Sus scrofa A0A287A5Q5 R-SSC-3451153 https://reactome.org/PathwayBrowser/#/R-SSC-3451153 Beta-catenin recruits TRRAP/KAT5 HAT components IEA Sus scrofa A0A287A5Q5 R-SSC-4411383 https://reactome.org/PathwayBrowser/#/R-SSC-4411383 NLK phosphorylates TCF/LEF IEA Sus scrofa A0A287A5Q5 R-SSC-5665608 https://reactome.org/PathwayBrowser/#/R-SSC-5665608 TCF:Beta-catenin binds SOX proteins IEA Sus scrofa A0A287A5Q5 R-SSC-8944349 https://reactome.org/PathwayBrowser/#/R-SSC-8944349 TLE tetramers bind TCF/LEF at WNT promoters IEA Sus scrofa A0A287A5Q5 R-SSC-8951428 https://reactome.org/PathwayBrowser/#/R-SSC-8951428 RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) IEA Sus scrofa A0A287A5Q5 R-SSC-9858647 https://reactome.org/PathwayBrowser/#/R-SSC-9858647 HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter IEA Sus scrofa A0A287A5S1 R-SSC-8873834 https://reactome.org/PathwayBrowser/#/R-SSC-8873834 STARD10 transports PC from ER membrane to lamellar body membrane IEA Sus scrofa A0A287A5S1 R-SSC-8873923 https://reactome.org/PathwayBrowser/#/R-SSC-8873923 STARD10 binds LPCAT1 and PC IEA Sus scrofa A0A287A5S1 R-SSC-8873929 https://reactome.org/PathwayBrowser/#/R-SSC-8873929 Casein kinase II phosphorylates STARD10 IEA Sus scrofa A0A287A5T0 R-SSC-6798739 https://reactome.org/PathwayBrowser/#/R-SSC-6798739 Exocytosis of azurophil granule membrane proteins IEA Sus scrofa A0A287A5T0 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A287A5T1 R-SSC-5695964 https://reactome.org/PathwayBrowser/#/R-SSC-5695964 ABHD14B hydrolyses PNPB IEA Sus scrofa A0A287A5V3 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A287A5V3 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A287A5V3 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A287A5V3 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A287A5V3 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287A5V3 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287A5V3 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287A5V3 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287A5V3 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287A5V3 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287A5V3 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A287A5V3 R-SSC-4655355 https://reactome.org/PathwayBrowser/#/R-SSC-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Sus scrofa A0A287A5V3 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A287A5V3 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A287A5V3 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A287A5V3 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287A5V7 R-SSC-481044 https://reactome.org/PathwayBrowser/#/R-SSC-481044 Surface deployment of platelet alpha granule membrane components IEA Sus scrofa A0A287A5V7 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A287A5W0 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287A5W0 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287A5W0 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287A5W0 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287A5W5 R-SSC-8849748 https://reactome.org/PathwayBrowser/#/R-SSC-8849748 The COG complex binds RABs at the Golgi membrane IEA Sus scrofa A0A287A5W5 R-SSC-8877813 https://reactome.org/PathwayBrowser/#/R-SSC-8877813 DENND5A,B exchange GTP for GDP on RAB39 IEA Sus scrofa A0A287A5Y5 R-SSC-8876188 https://reactome.org/PathwayBrowser/#/R-SSC-8876188 DENND4s exchange GTP for GDP on RAB10 IEA Sus scrofa A0A287A5Z9 R-SSC-163090 https://reactome.org/PathwayBrowser/#/R-SSC-163090 Elongation Of The Telomeric Chromosome End IEA Sus scrofa A0A287A5Z9 R-SSC-163096 https://reactome.org/PathwayBrowser/#/R-SSC-163096 Recruitment of Telomerase RNP to the Telomeric Chromosome End IEA Sus scrofa A0A287A5Z9 R-SSC-163099 https://reactome.org/PathwayBrowser/#/R-SSC-163099 Alignment Of The RNA Template On The Telomeric Chromosome End IEA Sus scrofa A0A287A5Z9 R-SSC-163120 https://reactome.org/PathwayBrowser/#/R-SSC-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Sus scrofa A0A287A5Z9 R-SSC-164617 https://reactome.org/PathwayBrowser/#/R-SSC-164617 Elongation of Extended Telomeric Chromosome End IEA Sus scrofa A0A287A5Z9 R-SSC-164620 https://reactome.org/PathwayBrowser/#/R-SSC-164620 Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End IEA Sus scrofa A0A287A5Z9 R-SSC-174425 https://reactome.org/PathwayBrowser/#/R-SSC-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Sus scrofa A0A287A5Z9 R-SSC-174427 https://reactome.org/PathwayBrowser/#/R-SSC-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Sus scrofa A0A287A5Z9 R-SSC-174438 https://reactome.org/PathwayBrowser/#/R-SSC-174438 Formation of the Flap Intermediate on the C-strand IEA Sus scrofa A0A287A5Z9 R-SSC-174439 https://reactome.org/PathwayBrowser/#/R-SSC-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Sus scrofa A0A287A5Z9 R-SSC-174441 https://reactome.org/PathwayBrowser/#/R-SSC-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Sus scrofa A0A287A5Z9 R-SSC-174444 https://reactome.org/PathwayBrowser/#/R-SSC-174444 Formation of C-strand Okazaki fragments IEA Sus scrofa A0A287A5Z9 R-SSC-174445 https://reactome.org/PathwayBrowser/#/R-SSC-174445 RPA binds to the Flap on the C-strand IEA Sus scrofa A0A287A5Z9 R-SSC-174446 https://reactome.org/PathwayBrowser/#/R-SSC-174446 Removal of remaining Flap from the C-strand IEA Sus scrofa A0A287A5Z9 R-SSC-174447 https://reactome.org/PathwayBrowser/#/R-SSC-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Sus scrofa A0A287A5Z9 R-SSC-174448 https://reactome.org/PathwayBrowser/#/R-SSC-174448 Formation of Processive Complex on the C-strand of the telomere IEA Sus scrofa A0A287A5Z9 R-SSC-174451 https://reactome.org/PathwayBrowser/#/R-SSC-174451 Recruitment of DNA2 endonuclease to the C strand IEA Sus scrofa A0A287A5Z9 R-SSC-174452 https://reactome.org/PathwayBrowser/#/R-SSC-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Sus scrofa A0A287A5Z9 R-SSC-174456 https://reactome.org/PathwayBrowser/#/R-SSC-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Sus scrofa A0A287A5Z9 R-SSC-176702 https://reactome.org/PathwayBrowser/#/R-SSC-176702 Disassociation of Processive Complex and Completed Telomere End IEA Sus scrofa A0A287A5Z9 R-SSC-3785711 https://reactome.org/PathwayBrowser/#/R-SSC-3785711 Telomere shortening during replicative exhaustion IEA Sus scrofa A0A287A5Z9 R-SSC-9629195 https://reactome.org/PathwayBrowser/#/R-SSC-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA IEA Sus scrofa A0A287A5Z9 R-SSC-9629216 https://reactome.org/PathwayBrowser/#/R-SSC-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Sus scrofa A0A287A5Z9 R-SSC-9668597 https://reactome.org/PathwayBrowser/#/R-SSC-9668597 DNA polymerase:primase binds G-strand of the telomere IEA Sus scrofa A0A287A5Z9 R-SSC-9670101 https://reactome.org/PathwayBrowser/#/R-SSC-9670101 ATRX:DAXX binds to subtelomeric chromosomal regions IEA Sus scrofa A0A287A5Z9 R-SSC-9686521 https://reactome.org/PathwayBrowser/#/R-SSC-9686521 CDK2:CCNA phosphorylates TERF2 IEA Sus scrofa A0A287A5Z9 R-SSC-9686524 https://reactome.org/PathwayBrowser/#/R-SSC-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Sus scrofa A0A287A629 R-SSC-6798749 https://reactome.org/PathwayBrowser/#/R-SSC-6798749 Exocytosis of specific granule lumen proteins IEA Sus scrofa A0A287A638 R-SSC-2130619 https://reactome.org/PathwayBrowser/#/R-SSC-2130619 TGN-lysosomal vesicle coat assembly IEA Sus scrofa A0A287A638 R-SSC-2130641 https://reactome.org/PathwayBrowser/#/R-SSC-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Sus scrofa A0A287A638 R-SSC-2213236 https://reactome.org/PathwayBrowser/#/R-SSC-2213236 TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome IEA Sus scrofa A0A287A638 R-SSC-421831 https://reactome.org/PathwayBrowser/#/R-SSC-421831 trans-Golgi Network Coat Assembly IEA Sus scrofa A0A287A638 R-SSC-421835 https://reactome.org/PathwayBrowser/#/R-SSC-421835 trans-Golgi Network Vesicle Scission IEA Sus scrofa A0A287A638 R-SSC-432706 https://reactome.org/PathwayBrowser/#/R-SSC-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Sus scrofa A0A287A638 R-SSC-432707 https://reactome.org/PathwayBrowser/#/R-SSC-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Sus scrofa A0A287A638 R-SSC-5333658 https://reactome.org/PathwayBrowser/#/R-SSC-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Sus scrofa A0A287A638 R-SSC-8951498 https://reactome.org/PathwayBrowser/#/R-SSC-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Sus scrofa A0A287A664 R-SSC-426240 https://reactome.org/PathwayBrowser/#/R-SSC-426240 DAG kinase produces phosphatidic acid from DAG IEA Sus scrofa A0A287A670 R-SSC-9023840 https://reactome.org/PathwayBrowser/#/R-SSC-9023840 HATs and coactivators are recruited to the CTSD gene IEA Sus scrofa A0A287A671 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A287A671 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa A0A287A671 R-SSC-9911661 https://reactome.org/PathwayBrowser/#/R-SSC-9911661 NOTCH2NLB, (NOTCH2NLA, NOTCH2NLC) bind DLL1, (DLL4, JAG1, JAG2) IEA Sus scrofa A0A287A673 R-SSC-8869241 https://reactome.org/PathwayBrowser/#/R-SSC-8869241 PITPNM1,2,3 exchange PI for PA IEA Sus scrofa A0A287A682 R-SSC-177479 https://reactome.org/PathwayBrowser/#/R-SSC-177479 Axonal transport of NGF:Trk complexes IEA Sus scrofa A0A287A682 R-SSC-190519 https://reactome.org/PathwayBrowser/#/R-SSC-190519 Internalization of gap junction plaques IEA Sus scrofa A0A287A682 R-SSC-190829 https://reactome.org/PathwayBrowser/#/R-SSC-190829 Lysosomal degradation of gap junction plaques IEA Sus scrofa A0A287A682 R-SSC-196017 https://reactome.org/PathwayBrowser/#/R-SSC-196017 Dynamin is recruited to the gap junction plaque IEA Sus scrofa A0A287A682 R-SSC-196026 https://reactome.org/PathwayBrowser/#/R-SSC-196026 Dab2 is recruited to the junctional plaques IEA Sus scrofa A0A287A682 R-SSC-2130486 https://reactome.org/PathwayBrowser/#/R-SSC-2130486 Uncoating of clathrin-coated vesicles and fusion with endosomes IEA Sus scrofa A0A287A682 R-SSC-2130619 https://reactome.org/PathwayBrowser/#/R-SSC-2130619 TGN-lysosomal vesicle coat assembly IEA Sus scrofa A0A287A682 R-SSC-2130640 https://reactome.org/PathwayBrowser/#/R-SSC-2130640 Recruitment of clathrin coated vesicle by Ii IEA Sus scrofa A0A287A682 R-SSC-2130641 https://reactome.org/PathwayBrowser/#/R-SSC-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Sus scrofa A0A287A682 R-SSC-2130725 https://reactome.org/PathwayBrowser/#/R-SSC-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Sus scrofa A0A287A682 R-SSC-2213236 https://reactome.org/PathwayBrowser/#/R-SSC-2213236 TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome IEA Sus scrofa A0A287A682 R-SSC-392749 https://reactome.org/PathwayBrowser/#/R-SSC-392749 Transport of L1 into endosomes IEA Sus scrofa A0A287A682 R-SSC-421831 https://reactome.org/PathwayBrowser/#/R-SSC-421831 trans-Golgi Network Coat Assembly IEA Sus scrofa A0A287A682 R-SSC-421835 https://reactome.org/PathwayBrowser/#/R-SSC-421835 trans-Golgi Network Vesicle Scission IEA Sus scrofa A0A287A682 R-SSC-432706 https://reactome.org/PathwayBrowser/#/R-SSC-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Sus scrofa A0A287A682 R-SSC-432707 https://reactome.org/PathwayBrowser/#/R-SSC-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Sus scrofa A0A287A682 R-SSC-445079 https://reactome.org/PathwayBrowser/#/R-SSC-445079 Phosphorylation of L1 by ERK IEA Sus scrofa A0A287A682 R-SSC-5138433 https://reactome.org/PathwayBrowser/#/R-SSC-5138433 p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis IEA Sus scrofa A0A287A682 R-SSC-5138459 https://reactome.org/PathwayBrowser/#/R-SSC-5138459 WNT5A:FZD4 is endocytosed IEA Sus scrofa A0A287A682 R-SSC-5140747 https://reactome.org/PathwayBrowser/#/R-SSC-5140747 FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner IEA Sus scrofa A0A287A682 R-SSC-5333658 https://reactome.org/PathwayBrowser/#/R-SSC-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Sus scrofa A0A287A682 R-SSC-555065 https://reactome.org/PathwayBrowser/#/R-SSC-555065 Formation of clathrin coated vesicle IEA Sus scrofa A0A287A682 R-SSC-6784729 https://reactome.org/PathwayBrowser/#/R-SSC-6784729 PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome IEA Sus scrofa A0A287A682 R-SSC-6784735 https://reactome.org/PathwayBrowser/#/R-SSC-6784735 PCSK9:LDLR bind to Clathrin IEA Sus scrofa A0A287A682 R-SSC-6784738 https://reactome.org/PathwayBrowser/#/R-SSC-6784738 Degradation of PCSK9:LDLR:Clathrin-coated vesicle IEA Sus scrofa A0A287A682 R-SSC-8855130 https://reactome.org/PathwayBrowser/#/R-SSC-8855130 VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane IEA Sus scrofa A0A287A682 R-SSC-8855131 https://reactome.org/PathwayBrowser/#/R-SSC-8855131 VLDLR:PCSK9 binds Clathrin-coated vesicles IEA Sus scrofa A0A287A682 R-SSC-8856808 https://reactome.org/PathwayBrowser/#/R-SSC-8856808 Recruitment of AP-2 complex and clathrin IEA Sus scrofa A0A287A682 R-SSC-8856813 https://reactome.org/PathwayBrowser/#/R-SSC-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Sus scrofa A0A287A682 R-SSC-8866279 https://reactome.org/PathwayBrowser/#/R-SSC-8866279 Epsin family proteins bind ubiquitinated cargo IEA Sus scrofa A0A287A682 R-SSC-8866283 https://reactome.org/PathwayBrowser/#/R-SSC-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Sus scrofa A0A287A682 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A287A682 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A287A682 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A287A682 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A287A682 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A287A682 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287A682 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287A682 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287A682 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287A682 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287A682 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287A682 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287A682 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287A682 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287A682 R-SSC-8871196 https://reactome.org/PathwayBrowser/#/R-SSC-8871196 Initial binding of AP-2 and clathrin to PI(4,5)P2 IEA Sus scrofa A0A287A682 R-SSC-8951498 https://reactome.org/PathwayBrowser/#/R-SSC-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Sus scrofa A0A287A685 R-SSC-1299359 https://reactome.org/PathwayBrowser/#/R-SSC-1299359 Activation of TALK IEA Sus scrofa A0A287A685 R-SSC-5578910 https://reactome.org/PathwayBrowser/#/R-SSC-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Sus scrofa A0A287A690 R-SSC-3341343 https://reactome.org/PathwayBrowser/#/R-SSC-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Sus scrofa A0A287A6A8 R-SSC-6799179 https://reactome.org/PathwayBrowser/#/R-SSC-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Sus scrofa A0A287A6A8 R-SSC-6799196 https://reactome.org/PathwayBrowser/#/R-SSC-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Sus scrofa A0A287A6C0 R-SSC-8877620 https://reactome.org/PathwayBrowser/#/R-SSC-8877620 ECE2 cleaves EDN1(53-90) IEA Sus scrofa A0A287A6C3 R-SSC-975449 https://reactome.org/PathwayBrowser/#/R-SSC-975449 GABRR pentamers:GABA transports extracellular Cl- to cytosol IEA Sus scrofa A0A287A6C7 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287A6C9 R-SSC-429663 https://reactome.org/PathwayBrowser/#/R-SSC-429663 SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol IEA Sus scrofa A0A287A6D5 R-SSC-5694433 https://reactome.org/PathwayBrowser/#/R-SSC-5694433 MIA2 binds PREB IEA Sus scrofa A0A287A6D5 R-SSC-5694435 https://reactome.org/PathwayBrowser/#/R-SSC-5694435 MIA2 and MIA3 load procollagen VII into COPII vesicles IEA Sus scrofa A0A287A6D5 R-SSC-5694436 https://reactome.org/PathwayBrowser/#/R-SSC-5694436 MIA2 and MIA3 dissociate from procollagen VII vesicle IEA Sus scrofa A0A287A6D8 R-SSC-399930 https://reactome.org/PathwayBrowser/#/R-SSC-399930 Activation of PAK by Rac1 IEA Sus scrofa A0A287A6D8 R-SSC-399933 https://reactome.org/PathwayBrowser/#/R-SSC-399933 Sema3A binds Nrp-1 bound to PlexinA IEA Sus scrofa A0A287A6D8 R-SSC-399939 https://reactome.org/PathwayBrowser/#/R-SSC-399939 Autophosphorylation of PAK IEA Sus scrofa A0A287A6D8 R-SSC-399944 https://reactome.org/PathwayBrowser/#/R-SSC-399944 Phosphorylation of CRMPs by Cdk5 IEA Sus scrofa A0A287A6D8 R-SSC-399947 https://reactome.org/PathwayBrowser/#/R-SSC-399947 Tyrosine phosphorylation of CRMPs by Fes IEA Sus scrofa A0A287A6D8 R-SSC-399951 https://reactome.org/PathwayBrowser/#/R-SSC-399951 Phosphorylation of CRMPs by GSK3beta IEA Sus scrofa A0A287A6D8 R-SSC-399952 https://reactome.org/PathwayBrowser/#/R-SSC-399952 Phosphorylation of LIMK-1 by PAK IEA Sus scrofa A0A287A6D8 R-SSC-416725 https://reactome.org/PathwayBrowser/#/R-SSC-416725 SEMA6D binds to PLXNA1:TREM2:DAP12 IEA Sus scrofa A0A287A6D8 R-SSC-9693198 https://reactome.org/PathwayBrowser/#/R-SSC-9693198 RHOD binds effectors at the plasma membrane IEA Sus scrofa A0A287A6D8 R-SSC-9696271 https://reactome.org/PathwayBrowser/#/R-SSC-9696271 RND1 binds effectors IEA Sus scrofa A0A287A6E7 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287A6G6 R-SSC-141348 https://reactome.org/PathwayBrowser/#/R-SSC-141348 PAO:FAD oxidises NASPM to PTCN IEA Sus scrofa A0A287A6G6 R-SSC-141351 https://reactome.org/PathwayBrowser/#/R-SSC-141351 PAOX:FAD oxidises NASPN to SPM IEA Sus scrofa A0A287A6G6 R-SSC-9033235 https://reactome.org/PathwayBrowser/#/R-SSC-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A287A6G6 R-SSC-9033236 https://reactome.org/PathwayBrowser/#/R-SSC-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Sus scrofa A0A287A6H2 R-SSC-5627071 https://reactome.org/PathwayBrowser/#/R-SSC-5627071 RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane IEA Sus scrofa A0A287A6H2 R-SSC-5627072 https://reactome.org/PathwayBrowser/#/R-SSC-5627072 RHOQ binds GOPC:CFTR IEA Sus scrofa A0A287A6H2 R-SSC-5627275 https://reactome.org/PathwayBrowser/#/R-SSC-5627275 GOPC promotes translocation of CFTR to lysosomes IEA Sus scrofa A0A287A6H7 R-SSC-8847875 https://reactome.org/PathwayBrowser/#/R-SSC-8847875 ARF1:GTP binds Golgin TRIP11 IEA Sus scrofa A0A287A6H7 R-SSC-8940388 https://reactome.org/PathwayBrowser/#/R-SSC-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Sus scrofa A0A287A6I1 R-SSC-4827382 https://reactome.org/PathwayBrowser/#/R-SSC-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Sus scrofa A0A287A6I2 R-SSC-1236398 https://reactome.org/PathwayBrowser/#/R-SSC-1236398 ERBB4 binds NRGs or EGF-like ligands IEA Sus scrofa A0A287A6I2 R-SSC-1250195 https://reactome.org/PathwayBrowser/#/R-SSC-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Sus scrofa A0A287A6I2 R-SSC-1250220 https://reactome.org/PathwayBrowser/#/R-SSC-1250220 Homodimerization of ERBB4 IEA Sus scrofa A0A287A6I2 R-SSC-1250315 https://reactome.org/PathwayBrowser/#/R-SSC-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Sus scrofa A0A287A6I2 R-SSC-1250346 https://reactome.org/PathwayBrowser/#/R-SSC-1250346 Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers IEA Sus scrofa A0A287A6I2 R-SSC-1250348 https://reactome.org/PathwayBrowser/#/R-SSC-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Sus scrofa A0A287A6I2 R-SSC-1250353 https://reactome.org/PathwayBrowser/#/R-SSC-1250353 Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers IEA Sus scrofa A0A287A6I2 R-SSC-1250357 https://reactome.org/PathwayBrowser/#/R-SSC-1250357 SHC1 binds P-ERBB4 isoform dimers IEA Sus scrofa A0A287A6I2 R-SSC-1250370 https://reactome.org/PathwayBrowser/#/R-SSC-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Sus scrofa A0A287A6I2 R-SSC-1250380 https://reactome.org/PathwayBrowser/#/R-SSC-1250380 Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers IEA Sus scrofa A0A287A6I2 R-SSC-1250383 https://reactome.org/PathwayBrowser/#/R-SSC-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Sus scrofa A0A287A6I2 R-SSC-1306969 https://reactome.org/PathwayBrowser/#/R-SSC-1306969 GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers IEA Sus scrofa A0A287A6I2 R-SSC-1306972 https://reactome.org/PathwayBrowser/#/R-SSC-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Sus scrofa A0A287A6I2 R-SSC-1306979 https://reactome.org/PathwayBrowser/#/R-SSC-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Sus scrofa A0A287A6I2 R-SSC-177922 https://reactome.org/PathwayBrowser/#/R-SSC-177922 EGFR dimerization IEA Sus scrofa A0A287A6I2 R-SSC-177923 https://reactome.org/PathwayBrowser/#/R-SSC-177923 Sustained activation of SRC kinase by SHP2 IEA Sus scrofa A0A287A6I2 R-SSC-177924 https://reactome.org/PathwayBrowser/#/R-SSC-177924 Dephosphorylation of Gab1 by SHP2 IEA Sus scrofa A0A287A6I2 R-SSC-177925 https://reactome.org/PathwayBrowser/#/R-SSC-177925 SHC1 binds to the phosphorylated EGF receptor:ligand complex IEA Sus scrofa A0A287A6I2 R-SSC-177926 https://reactome.org/PathwayBrowser/#/R-SSC-177926 Dephosphorylation of PAG by SHP2 IEA Sus scrofa A0A287A6I2 R-SSC-177927 https://reactome.org/PathwayBrowser/#/R-SSC-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 IEA Sus scrofa A0A287A6I2 R-SSC-177930 https://reactome.org/PathwayBrowser/#/R-SSC-177930 GAB1 phosphorylation by EGFR kinase IEA Sus scrofa A0A287A6I2 R-SSC-177933 https://reactome.org/PathwayBrowser/#/R-SSC-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Sus scrofa A0A287A6I2 R-SSC-177934 https://reactome.org/PathwayBrowser/#/R-SSC-177934 EGFR autophosphorylation IEA Sus scrofa A0A287A6I2 R-SSC-177935 https://reactome.org/PathwayBrowser/#/R-SSC-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Sus scrofa A0A287A6I2 R-SSC-177936 https://reactome.org/PathwayBrowser/#/R-SSC-177936 GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR IEA Sus scrofa A0A287A6I2 R-SSC-177937 https://reactome.org/PathwayBrowser/#/R-SSC-177937 Phosphorylation of EGFR by SRC kinase IEA Sus scrofa A0A287A6I2 R-SSC-177938 https://reactome.org/PathwayBrowser/#/R-SSC-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Sus scrofa A0A287A6I2 R-SSC-177939 https://reactome.org/PathwayBrowser/#/R-SSC-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Sus scrofa A0A287A6I2 R-SSC-177941 https://reactome.org/PathwayBrowser/#/R-SSC-177941 GRB2:GAB1 binds to phosphorylated EGFR IEA Sus scrofa A0A287A6I2 R-SSC-177942 https://reactome.org/PathwayBrowser/#/R-SSC-177942 EGFR binds EGF ligand IEA Sus scrofa A0A287A6I2 R-SSC-177943 https://reactome.org/PathwayBrowser/#/R-SSC-177943 GRB2:SOS1 complex binds to EGF:EGFR complex IEA Sus scrofa A0A287A6I2 R-SSC-177944 https://reactome.org/PathwayBrowser/#/R-SSC-177944 Activation of SHP2 through the binding to phospho-Gab1 IEA Sus scrofa A0A287A6I2 R-SSC-177945 https://reactome.org/PathwayBrowser/#/R-SSC-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Sus scrofa A0A287A6I2 R-SSC-182969 https://reactome.org/PathwayBrowser/#/R-SSC-182969 Phosphorylation of CBL (EGFR:CBL) IEA Sus scrofa A0A287A6I2 R-SSC-182986 https://reactome.org/PathwayBrowser/#/R-SSC-182986 CBL-mediated ubiquitination of CIN85 IEA Sus scrofa A0A287A6I2 R-SSC-182990 https://reactome.org/PathwayBrowser/#/R-SSC-182990 Sprouty sequesters CBL away from active EGFR IEA Sus scrofa A0A287A6I2 R-SSC-182993 https://reactome.org/PathwayBrowser/#/R-SSC-182993 Ubiquitination of stimulated EGFR (CBL) IEA Sus scrofa A0A287A6I2 R-SSC-182994 https://reactome.org/PathwayBrowser/#/R-SSC-182994 Assembly of EGFR complex in clathrin-coated vesicles IEA Sus scrofa A0A287A6I2 R-SSC-183002 https://reactome.org/PathwayBrowser/#/R-SSC-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Sus scrofa A0A287A6I2 R-SSC-183036 https://reactome.org/PathwayBrowser/#/R-SSC-183036 Ubiquitination of stimulated EGFR (CBL:GRB2) IEA Sus scrofa A0A287A6I2 R-SSC-183051 https://reactome.org/PathwayBrowser/#/R-SSC-183051 CBL ubiquitinates Sprouty IEA Sus scrofa A0A287A6I2 R-SSC-183055 https://reactome.org/PathwayBrowser/#/R-SSC-183055 Binding of CBL to EGFR IEA Sus scrofa A0A287A6I2 R-SSC-183058 https://reactome.org/PathwayBrowser/#/R-SSC-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Sus scrofa A0A287A6I2 R-SSC-183067 https://reactome.org/PathwayBrowser/#/R-SSC-183067 Localization of CBL:GRB2 to the membrane IEA Sus scrofa A0A287A6I2 R-SSC-183072 https://reactome.org/PathwayBrowser/#/R-SSC-183072 EGFR non-clathrin mediated endocytosis IEA Sus scrofa A0A287A6I2 R-SSC-183084 https://reactome.org/PathwayBrowser/#/R-SSC-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Sus scrofa A0A287A6I2 R-SSC-183089 https://reactome.org/PathwayBrowser/#/R-SSC-183089 CBL binds and ubiquitinates phosphorylated Sprouty IEA Sus scrofa A0A287A6I2 R-SSC-1963563 https://reactome.org/PathwayBrowser/#/R-SSC-1963563 MATK (CSK homologous kinase) binds phosphorylated ERBB2 IEA Sus scrofa A0A287A6I2 R-SSC-1963581 https://reactome.org/PathwayBrowser/#/R-SSC-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Sus scrofa A0A287A6I2 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa A0A287A6I2 R-SSC-1963586 https://reactome.org/PathwayBrowser/#/R-SSC-1963586 SRC family kinases phosphorylate ERBB2 IEA Sus scrofa A0A287A6I2 R-SSC-1977958 https://reactome.org/PathwayBrowser/#/R-SSC-1977958 ERBB4 forms heterodimers with ERBB3 IEA Sus scrofa A0A287A6I2 R-SSC-1977959 https://reactome.org/PathwayBrowser/#/R-SSC-1977959 ERBB4 forms heterodimers with EGFR IEA Sus scrofa A0A287A6I2 R-SSC-212706 https://reactome.org/PathwayBrowser/#/R-SSC-212706 Phospholipase C-gamma1 binds to the activated EGF receptor IEA Sus scrofa A0A287A6I2 R-SSC-212710 https://reactome.org/PathwayBrowser/#/R-SSC-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Sus scrofa A0A287A6I2 R-SSC-212713 https://reactome.org/PathwayBrowser/#/R-SSC-212713 Active PLC-gamma1 dissociates from EGFR IEA Sus scrofa A0A287A6I2 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287A6I2 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287A6I2 R-SSC-6785636 https://reactome.org/PathwayBrowser/#/R-SSC-6785636 Phosphorylated ERBB2 heterodimers bind MEMO1 IEA Sus scrofa A0A287A6I2 R-SSC-6785648 https://reactome.org/PathwayBrowser/#/R-SSC-6785648 MEMO1 binds RHOA:GTP:DIAPH1 IEA Sus scrofa A0A287A6I2 R-SSC-8847995 https://reactome.org/PathwayBrowser/#/R-SSC-8847995 Activated ERBB2 binds PTK6 (BRK) IEA Sus scrofa A0A287A6I2 R-SSC-8848005 https://reactome.org/PathwayBrowser/#/R-SSC-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Sus scrofa A0A287A6I2 R-SSC-8863804 https://reactome.org/PathwayBrowser/#/R-SSC-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Sus scrofa A0A287A6I2 R-SSC-8866279 https://reactome.org/PathwayBrowser/#/R-SSC-8866279 Epsin family proteins bind ubiquitinated cargo IEA Sus scrofa A0A287A6I2 R-SSC-8867041 https://reactome.org/PathwayBrowser/#/R-SSC-8867041 EGFR phosphorylates EPS15 IEA Sus scrofa A0A287A6I2 R-SSC-8867044 https://reactome.org/PathwayBrowser/#/R-SSC-8867044 EGFR binds EPS15, EPN1, EPS15L1 IEA Sus scrofa A0A287A6I2 R-SSC-8867047 https://reactome.org/PathwayBrowser/#/R-SSC-8867047 PTPN3 dephosphorylates EPS15 IEA Sus scrofa A0A287A6I2 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A287A6I2 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A287A6I2 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A287A6I2 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A287A6I2 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A287A6I2 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287A6I2 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287A6I2 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287A6I2 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287A6I2 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287A6I2 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287A6I2 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287A6I2 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287A6I2 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287A6I2 R-SSC-8951490 https://reactome.org/PathwayBrowser/#/R-SSC-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Sus scrofa A0A287A6L6 R-SSC-114252 https://reactome.org/PathwayBrowser/#/R-SSC-114252 Cleavage of Procaspase-3 by the apoptosome IEA Sus scrofa A0A287A6L6 R-SSC-114261 https://reactome.org/PathwayBrowser/#/R-SSC-114261 Cleavage of Procaspase-7 by the apoptosome IEA Sus scrofa A0A287A6L6 R-SSC-114354 https://reactome.org/PathwayBrowser/#/R-SSC-114354 SMAC binds XIAP:Caspase-7 IEA Sus scrofa A0A287A6L6 R-SSC-114392 https://reactome.org/PathwayBrowser/#/R-SSC-114392 Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 IEA Sus scrofa A0A287A6L6 R-SSC-3322429 https://reactome.org/PathwayBrowser/#/R-SSC-3322429 XIAP monoubiquinates TLE IEA Sus scrofa A0A287A6L6 R-SSC-3322431 https://reactome.org/PathwayBrowser/#/R-SSC-3322431 XIAP binds TLE IEA Sus scrofa A0A287A6L6 R-SSC-3322434 https://reactome.org/PathwayBrowser/#/R-SSC-3322434 XIAP dissociates from ub-TLE IEA Sus scrofa A0A287A6L6 R-SSC-5357757 https://reactome.org/PathwayBrowser/#/R-SSC-5357757 BIRC(cIAP1/2) ubiquitinates RIPK1 IEA Sus scrofa A0A287A6L6 R-SSC-5357776 https://reactome.org/PathwayBrowser/#/R-SSC-5357776 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG IEA Sus scrofa A0A287A6L6 R-SSC-5357780 https://reactome.org/PathwayBrowser/#/R-SSC-5357780 TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) IEA Sus scrofa A0A287A6L6 R-SSC-5357845 https://reactome.org/PathwayBrowser/#/R-SSC-5357845 K63polyUb-RIPK1 is deubiquitinated IEA Sus scrofa A0A287A6L6 R-SSC-5357860 https://reactome.org/PathwayBrowser/#/R-SSC-5357860 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex IEA Sus scrofa A0A287A6L6 R-SSC-5357928 https://reactome.org/PathwayBrowser/#/R-SSC-5357928 CLIP3 and CYLD bind TNF signaling complex IEA Sus scrofa A0A287A6L6 R-SSC-5668414 https://reactome.org/PathwayBrowser/#/R-SSC-5668414 TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK IEA Sus scrofa A0A287A6L6 R-SSC-5668417 https://reactome.org/PathwayBrowser/#/R-SSC-5668417 cIAP1,2:TRAF2:TRAF3:NIK complex binds TNFR2 trimer IEA Sus scrofa A0A287A6L6 R-SSC-5668534 https://reactome.org/PathwayBrowser/#/R-SSC-5668534 cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK IEA Sus scrofa A0A287A6L6 R-SSC-5668543 https://reactome.org/PathwayBrowser/#/R-SSC-5668543 TRAF3:NIK binds TRAF2:cIAP1/2 IEA Sus scrofa A0A287A6L6 R-SSC-5675470 https://reactome.org/PathwayBrowser/#/R-SSC-5675470 BIRC2/3 (cIAP1/2) is autoubiquitinated IEA Sus scrofa A0A287A6L6 R-SSC-5676593 https://reactome.org/PathwayBrowser/#/R-SSC-5676593 TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR IEA Sus scrofa A0A287A6L6 R-SSC-5676595 https://reactome.org/PathwayBrowser/#/R-SSC-5676595 TRAFs bind RANK:RANKL IEA Sus scrofa A0A287A6L6 R-SSC-5676596 https://reactome.org/PathwayBrowser/#/R-SSC-5676596 TRAF3 binds BAFFR:BAFF IEA Sus scrofa A0A287A6L6 R-SSC-5676597 https://reactome.org/PathwayBrowser/#/R-SSC-5676597 TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 IEA Sus scrofa A0A287A6L6 R-SSC-5676598 https://reactome.org/PathwayBrowser/#/R-SSC-5676598 TRAF2:cIAP1/2 complex binds FN14:TWEAK IEA Sus scrofa A0A287A6L6 R-SSC-5693055 https://reactome.org/PathwayBrowser/#/R-SSC-5693055 TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes IEA Sus scrofa A0A287A6L6 R-SSC-5693108 https://reactome.org/PathwayBrowser/#/R-SSC-5693108 TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains IEA Sus scrofa A0A287A6L6 R-SSC-6807106 https://reactome.org/PathwayBrowser/#/R-SSC-6807106 PTEN undergoes monoubiquitination IEA Sus scrofa A0A287A6L6 R-SSC-6807134 https://reactome.org/PathwayBrowser/#/R-SSC-6807134 NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN IEA Sus scrofa A0A287A6L6 R-SSC-83582 https://reactome.org/PathwayBrowser/#/R-SSC-83582 TRADD:TRAF2:RIP1 dissociates from TNF-α:TNFR1 IEA Sus scrofa A0A287A6L6 R-SSC-9627078 https://reactome.org/PathwayBrowser/#/R-SSC-9627078 XIAP binds CASP9 IEA Sus scrofa A0A287A6L6 R-SSC-9627104 https://reactome.org/PathwayBrowser/#/R-SSC-9627104 XIAP binds CASP3 IEA Sus scrofa A0A287A6L6 R-SSC-9627107 https://reactome.org/PathwayBrowser/#/R-SSC-9627107 XIAP binds CASP7 IEA Sus scrofa A0A287A6L6 R-SSC-9627350 https://reactome.org/PathwayBrowser/#/R-SSC-9627350 SMAC (DIABLO) binds XIAP IEA Sus scrofa A0A287A6L6 R-SSC-9627369 https://reactome.org/PathwayBrowser/#/R-SSC-9627369 SEPT4 binds XIAP IEA Sus scrofa A0A287A6L6 R-SSC-9793679 https://reactome.org/PathwayBrowser/#/R-SSC-9793679 LUBAC ubiquitinates RIPK1 at K627 IEA Sus scrofa A0A287A6L6 R-SSC-9793680 https://reactome.org/PathwayBrowser/#/R-SSC-9793680 OPTN binds polyUb-RIPK1 within the TNFR1 complex IEA Sus scrofa A0A287A6L6 R-SSC-9796379 https://reactome.org/PathwayBrowser/#/R-SSC-9796379 CYLD:SPATA2:LUBAC binds TNFR1 signaling complex IEA Sus scrofa A0A287A6L6 R-SSC-9817362 https://reactome.org/PathwayBrowser/#/R-SSC-9817362 SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex IEA Sus scrofa A0A287A6L6 R-SSC-9817397 https://reactome.org/PathwayBrowser/#/R-SSC-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Sus scrofa A0A287A6L6 R-SSC-9817400 https://reactome.org/PathwayBrowser/#/R-SSC-9817400 CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex IEA Sus scrofa A0A287A6L6 R-SSC-9817411 https://reactome.org/PathwayBrowser/#/R-SSC-9817411 TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex IEA Sus scrofa A0A287A6L6 R-SSC-9818789 https://reactome.org/PathwayBrowser/#/R-SSC-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 IEA Sus scrofa A0A287A6L6 R-SSC-9818975 https://reactome.org/PathwayBrowser/#/R-SSC-9818975 CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex IEA Sus scrofa A0A287A6L6 R-SSC-9824874 https://reactome.org/PathwayBrowser/#/R-SSC-9824874 OPTN recruits CYLD to the TNFR1 complex IEA Sus scrofa A0A287A6M0 R-SSC-3247837 https://reactome.org/PathwayBrowser/#/R-SSC-3247837 WNT ligands traffic to the Golgi IEA Sus scrofa A0A287A6M0 R-SSC-3247840 https://reactome.org/PathwayBrowser/#/R-SSC-3247840 WLS binds WNT ligands in the Golgi IEA Sus scrofa A0A287A6M0 R-SSC-3247843 https://reactome.org/PathwayBrowser/#/R-SSC-3247843 secretion of WNT ligands IEA Sus scrofa A0A287A6M0 R-SSC-3247844 https://reactome.org/PathwayBrowser/#/R-SSC-3247844 WNT ligands traffic to the plasma membrane IEA Sus scrofa A0A287A6M0 R-SSC-3781941 https://reactome.org/PathwayBrowser/#/R-SSC-3781941 WNTs are secreted in exosomes IEA Sus scrofa A0A287A6M0 R-SSC-3781943 https://reactome.org/PathwayBrowser/#/R-SSC-3781943 WLS:WNT complex is internalized for maturation into exosomes IEA Sus scrofa A0A287A6N0 R-SSC-913675 https://reactome.org/PathwayBrowser/#/R-SSC-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Sus scrofa A0A287A6Q0 R-SSC-141026 https://reactome.org/PathwayBrowser/#/R-SSC-141026 Activated protein C cleaves factor Va to factor Vi intermediate form IEA Sus scrofa A0A287A6Q0 R-SSC-159729 https://reactome.org/PathwayBrowser/#/R-SSC-159729 Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus IEA Sus scrofa A0A287A6Q0 R-SSC-159752 https://reactome.org/PathwayBrowser/#/R-SSC-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Sus scrofa A0A287A6Q0 R-SSC-159773 https://reactome.org/PathwayBrowser/#/R-SSC-159773 Furin cleaves pro-protein S to protein S IEA Sus scrofa A0A287A6Q0 R-SSC-202710 https://reactome.org/PathwayBrowser/#/R-SSC-202710 MERTK receptor binds ligands (Gas6 or Protein S) IEA Sus scrofa A0A287A6Q0 R-SSC-481007 https://reactome.org/PathwayBrowser/#/R-SSC-481007 Exocytosis of platelet alpha granule contents IEA Sus scrofa A0A287A6Q0 R-SSC-5591040 https://reactome.org/PathwayBrowser/#/R-SSC-5591040 Activated protein C cleaves Factor Va intermediate form for Factor Va IEA Sus scrofa A0A287A6Q0 R-SSC-5604929 https://reactome.org/PathwayBrowser/#/R-SSC-5604929 Activated protein C binds Protein S IEA Sus scrofa A0A287A6Q8 R-SSC-448661 https://reactome.org/PathwayBrowser/#/R-SSC-448661 IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 IEA Sus scrofa A0A287A6Q8 R-SSC-8986985 https://reactome.org/PathwayBrowser/#/R-SSC-8986985 IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 IEA Sus scrofa A0A287A6Q8 R-SSC-8987033 https://reactome.org/PathwayBrowser/#/R-SSC-8987033 p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 IEA Sus scrofa A0A287A6Q8 R-SSC-8987040 https://reactome.org/PathwayBrowser/#/R-SSC-8987040 IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 IEA Sus scrofa A0A287A6Q8 R-SSC-8987202 https://reactome.org/PathwayBrowser/#/R-SSC-8987202 IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 IEA Sus scrofa A0A287A6Q8 R-SSC-8987266 https://reactome.org/PathwayBrowser/#/R-SSC-8987266 IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 IEA Sus scrofa A0A287A6Q9 R-SSC-6795290 https://reactome.org/PathwayBrowser/#/R-SSC-6795290 TORC2 complex phosphorylates SGK1 IEA Sus scrofa A0A287A6R9 R-SSC-1482861 https://reactome.org/PathwayBrowser/#/R-SSC-1482861 MLCL is acylated to CL by LCLAT1 (ER) IEA Sus scrofa A0A287A6R9 R-SSC-1482867 https://reactome.org/PathwayBrowser/#/R-SSC-1482867 DLCL is acylated to MLCL by LCLAT1 (ER) IEA Sus scrofa A0A287A6R9 R-SSC-75885 https://reactome.org/PathwayBrowser/#/R-SSC-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Sus scrofa A0A287A6S6 R-SSC-3222128 https://reactome.org/PathwayBrowser/#/R-SSC-3222128 NOC2L binds TP53 IEA Sus scrofa A0A287A6S6 R-SSC-6805122 https://reactome.org/PathwayBrowser/#/R-SSC-6805122 AURKB binds TP53 IEA Sus scrofa A0A287A6S6 R-SSC-6805126 https://reactome.org/PathwayBrowser/#/R-SSC-6805126 AURKB phosphorylates TP53 IEA Sus scrofa A0A287A6V9 R-SSC-6786190 https://reactome.org/PathwayBrowser/#/R-SSC-6786190 CMBL hydrolyses OM to OLMS IEA Sus scrofa A0A287A6X0 R-SSC-3371422 https://reactome.org/PathwayBrowser/#/R-SSC-3371422 ATP hydrolysis by HSP70 IEA Sus scrofa A0A287A6X0 R-SSC-3371467 https://reactome.org/PathwayBrowser/#/R-SSC-3371467 SIRT1 deacetylates HSF1 IEA Sus scrofa A0A287A6X0 R-SSC-3371503 https://reactome.org/PathwayBrowser/#/R-SSC-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein IEA Sus scrofa A0A287A6X0 R-SSC-3371518 https://reactome.org/PathwayBrowser/#/R-SSC-3371518 SIRT1 binds to HSF1 IEA Sus scrofa A0A287A6X0 R-SSC-3371554 https://reactome.org/PathwayBrowser/#/R-SSC-3371554 HSF1 acetylation at Lys80 IEA Sus scrofa A0A287A6X0 R-SSC-3371590 https://reactome.org/PathwayBrowser/#/R-SSC-3371590 HSP70 binds to HSP40:nascent protein IEA Sus scrofa A0A287A6X0 R-SSC-5082356 https://reactome.org/PathwayBrowser/#/R-SSC-5082356 HSF1-mediated gene expression IEA Sus scrofa A0A287A6X0 R-SSC-5082384 https://reactome.org/PathwayBrowser/#/R-SSC-5082384 HSP70:DNAJB1 binds HSF1 IEA Sus scrofa A0A287A6X0 R-SSC-5251955 https://reactome.org/PathwayBrowser/#/R-SSC-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Sus scrofa A0A287A6X0 R-SSC-5251959 https://reactome.org/PathwayBrowser/#/R-SSC-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Sus scrofa A0A287A6X0 R-SSC-5690245 https://reactome.org/PathwayBrowser/#/R-SSC-5690245 p-T182 MAPKAPK5 binds DNAJB1 IEA Sus scrofa A0A287A6X0 R-SSC-5690250 https://reactome.org/PathwayBrowser/#/R-SSC-5690250 p-T182-MAPKAPK5 phoshphorylates DNAJB1 IEA Sus scrofa A0A287A6X2 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287A6X2 R-SSC-9026894 https://reactome.org/PathwayBrowser/#/R-SSC-9026894 Activated PCLG1 dissociates from NTRK2 IEA Sus scrofa A0A287A6X2 R-SSC-9028730 https://reactome.org/PathwayBrowser/#/R-SSC-9028730 Activated NTRK2 binds FRS2 IEA Sus scrofa A0A287A6X2 R-SSC-9032073 https://reactome.org/PathwayBrowser/#/R-SSC-9032073 NTRK2-phosphorylated FRS2 binds GRB2 IEA Sus scrofa A0A287A6X2 R-SSC-9032798 https://reactome.org/PathwayBrowser/#/R-SSC-9032798 DOCK3 activates RAC1 IEA Sus scrofa A0A287A6X5 R-SSC-9839072 https://reactome.org/PathwayBrowser/#/R-SSC-9839072 HTRA2 degrades APP (Amyloid-beta precursor protein) IEA Sus scrofa A0A287A6X5 R-SSC-9839073 https://reactome.org/PathwayBrowser/#/R-SSC-9839073 HTRA2 binds NDUFA13 (GRIM-19) IEA Sus scrofa A0A287A6X5 R-SSC-9839110 https://reactome.org/PathwayBrowser/#/R-SSC-9839110 HTRA2 degrades NDUFA13 (GRIM-19) IEA Sus scrofa A0A287A6Z9 R-SSC-6804441 https://reactome.org/PathwayBrowser/#/R-SSC-6804441 RNF34 or RFFL ubiquitinates phosphorylated TP53 IEA Sus scrofa A0A287A706 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287A706 R-SSC-444523 https://reactome.org/PathwayBrowser/#/R-SSC-444523 CXCR5 binds CXCL13 IEA Sus scrofa A0A287A706 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287A706 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287A719 R-SSC-6795290 https://reactome.org/PathwayBrowser/#/R-SSC-6795290 TORC2 complex phosphorylates SGK1 IEA Sus scrofa A0A287A719 R-SSC-6795460 https://reactome.org/PathwayBrowser/#/R-SSC-6795460 SGK1 phosphorylates MDM2 IEA Sus scrofa A0A287A719 R-SSC-6795473 https://reactome.org/PathwayBrowser/#/R-SSC-6795473 PDPK1 phosphorylates SGK1 IEA Sus scrofa A0A287A719 R-SSC-9612501 https://reactome.org/PathwayBrowser/#/R-SSC-9612501 SGK phosphorylates CREB1 IEA Sus scrofa A0A287A719 R-SSC-9612509 https://reactome.org/PathwayBrowser/#/R-SSC-9612509 SGK phosphorylates SRF IEA Sus scrofa A0A287A731 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A287A731 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A287A731 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A287A731 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A287A731 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A287A740 R-SSC-1474210 https://reactome.org/PathwayBrowser/#/R-SSC-1474210 Collagen type III degradation by MMP14 IEA Sus scrofa A0A287A740 R-SSC-1592349 https://reactome.org/PathwayBrowser/#/R-SSC-1592349 MMP14 (MT1-MMP) binds TIMP2 IEA Sus scrofa A0A287A740 R-SSC-1602466 https://reactome.org/PathwayBrowser/#/R-SSC-1602466 Activation of MT-MMPs by FURIN IEA Sus scrofa A0A287A740 R-SSC-1604350 https://reactome.org/PathwayBrowser/#/R-SSC-1604350 MMP14:TIMP2 binds proMMP2 IEA Sus scrofa A0A287A740 R-SSC-1604360 https://reactome.org/PathwayBrowser/#/R-SSC-1604360 Initial activation of proMMP2 by MMP14 IEA Sus scrofa A0A287A740 R-SSC-1604368 https://reactome.org/PathwayBrowser/#/R-SSC-1604368 Autocatalytic activation of bound proMMP2 IEA Sus scrofa A0A287A740 R-SSC-1604741 https://reactome.org/PathwayBrowser/#/R-SSC-1604741 Initial activation of proMMP13 by MMP14 (MT1-MMP) IEA Sus scrofa A0A287A740 R-SSC-1605825 https://reactome.org/PathwayBrowser/#/R-SSC-1605825 MT-MMPs are sorted to the plasma membrane IEA Sus scrofa A0A287A740 R-SSC-2514790 https://reactome.org/PathwayBrowser/#/R-SSC-2514790 Elastin degradation by MMP14 IEA Sus scrofa A0A287A740 R-SSC-2533950 https://reactome.org/PathwayBrowser/#/R-SSC-2533950 Fibronectin degradation by MMP14 IEA Sus scrofa A0A287A740 R-SSC-3828025 https://reactome.org/PathwayBrowser/#/R-SSC-3828025 DCN (decorin) degradation by MMP14 IEA Sus scrofa A0A287A740 R-SSC-9839367 https://reactome.org/PathwayBrowser/#/R-SSC-9839367 TGFBR3_mem cleavage by MMPs IEA Sus scrofa A0A287A767 R-SSC-1475022 https://reactome.org/PathwayBrowser/#/R-SSC-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Sus scrofa A0A287A767 R-SSC-1475026 https://reactome.org/PathwayBrowser/#/R-SSC-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Sus scrofa A0A287A769 R-SSC-6787540 https://reactome.org/PathwayBrowser/#/R-SSC-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Sus scrofa A0A287A777 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287A799 R-SSC-5696600 https://reactome.org/PathwayBrowser/#/R-SSC-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Sus scrofa A0A287A799 R-SSC-9647999 https://reactome.org/PathwayBrowser/#/R-SSC-9647999 RCE1 cleaves S-Farn proRAS proteins IEA Sus scrofa A0A287A799 R-SSC-9653514 https://reactome.org/PathwayBrowser/#/R-SSC-9653514 USP17L2 deubiquitinates RCE1 IEA Sus scrofa A0A287A7A4 R-SSC-450027 https://reactome.org/PathwayBrowser/#/R-SSC-450027 Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta IEA Sus scrofa A0A287A7A4 R-SSC-450054 https://reactome.org/PathwayBrowser/#/R-SSC-450054 Interleukin-2 receptor alpha binds interleukin-2 IEA Sus scrofa A0A287A7A4 R-SSC-450063 https://reactome.org/PathwayBrowser/#/R-SSC-450063 Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit IEA Sus scrofa A0A287A7A4 R-SSC-451942 https://reactome.org/PathwayBrowser/#/R-SSC-451942 Within the IL-2R complex JAK3 phosphorylates JAK1 IEA Sus scrofa A0A287A7A4 R-SSC-452091 https://reactome.org/PathwayBrowser/#/R-SSC-452091 Phosphorylation of IL2RB Y338 enables SHC recruitment IEA Sus scrofa A0A287A7A4 R-SSC-452097 https://reactome.org/PathwayBrowser/#/R-SSC-452097 Recruited STAT5 is phosphorylated IEA Sus scrofa A0A287A7A4 R-SSC-452100 https://reactome.org/PathwayBrowser/#/R-SSC-452100 SHC1 bound to IL2 receptor is phosphorylated IEA Sus scrofa A0A287A7A4 R-SSC-452108 https://reactome.org/PathwayBrowser/#/R-SSC-452108 Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment IEA Sus scrofa A0A287A7A4 R-SSC-452122 https://reactome.org/PathwayBrowser/#/R-SSC-452122 JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB IEA Sus scrofa A0A287A7A4 R-SSC-453104 https://reactome.org/PathwayBrowser/#/R-SSC-453104 Phosphorylated SHC1 recruits GRB2:GAB2 IEA Sus scrofa A0A287A7A4 R-SSC-453111 https://reactome.org/PathwayBrowser/#/R-SSC-453111 Phosphorylated SHC recruits GRB2:SOS1 IEA Sus scrofa A0A287A7A4 R-SSC-508247 https://reactome.org/PathwayBrowser/#/R-SSC-508247 Gab2 binds the p85 subunit of Class 1A PI3 kinases IEA Sus scrofa A0A287A7A4 R-SSC-508282 https://reactome.org/PathwayBrowser/#/R-SSC-508282 SYK is a substrate for JAK1 IEA Sus scrofa A0A287A7A4 R-SSC-508292 https://reactome.org/PathwayBrowser/#/R-SSC-508292 SYK binds IL2RB IEA Sus scrofa A0A287A7A4 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287A7A4 R-SSC-912527 https://reactome.org/PathwayBrowser/#/R-SSC-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Sus scrofa A0A287A7A4 R-SSC-913374 https://reactome.org/PathwayBrowser/#/R-SSC-913374 Phosphorylated SHC1 recruits SHIP IEA Sus scrofa A0A287A7A4 R-SSC-913424 https://reactome.org/PathwayBrowser/#/R-SSC-913424 The SHC1:SHIP1 complex is stabilized by GRB2 IEA Sus scrofa A0A287A7A4 R-SSC-919404 https://reactome.org/PathwayBrowser/#/R-SSC-919404 Phosphorylated STAT5 is released IEA Sus scrofa A0A287A7A5 R-SSC-3108203 https://reactome.org/PathwayBrowser/#/R-SSC-3108203 PRC1 SUMOylates CTBP1 with SUMO2,3 IEA Sus scrofa A0A287A7A5 R-SSC-3108209 https://reactome.org/PathwayBrowser/#/R-SSC-3108209 PRC1 SUMOylates CTBP1 with SUMO1 IEA Sus scrofa A0A287A7A5 R-SSC-3927824 https://reactome.org/PathwayBrowser/#/R-SSC-3927824 PRC1 SUMOylates CASP8AP2 with SUMO1 IEA Sus scrofa A0A287A7A5 R-SSC-4551655 https://reactome.org/PathwayBrowser/#/R-SSC-4551655 CBX4 SUMOylates BMI1 in PRC1 with SUMO1 IEA Sus scrofa A0A287A7A5 R-SSC-4551727 https://reactome.org/PathwayBrowser/#/R-SSC-4551727 CBX4 SUMOylates CBX4 in PRC1 with SUMO1 IEA Sus scrofa A0A287A7A5 R-SSC-4570463 https://reactome.org/PathwayBrowser/#/R-SSC-4570463 CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 IEA Sus scrofa A0A287A7A5 R-SSC-4570499 https://reactome.org/PathwayBrowser/#/R-SSC-4570499 CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 IEA Sus scrofa A0A287A7A5 R-SSC-8954082 https://reactome.org/PathwayBrowser/#/R-SSC-8954082 E2F6 binds the PRC1 complex IEA Sus scrofa A0A287A7B3 R-SSC-5692315 https://reactome.org/PathwayBrowser/#/R-SSC-5692315 OX40L binds OX40 IEA Sus scrofa A0A287A7C6 R-SSC-2396399 https://reactome.org/PathwayBrowser/#/R-SSC-2396399 Fibrillins bind BMPs IEA Sus scrofa A0A287A7C6 R-SSC-8858369 https://reactome.org/PathwayBrowser/#/R-SSC-8858369 ACVRL1 binds BMP9,BMP10 IEA Sus scrofa A0A287A7C8 R-SSC-5688797 https://reactome.org/PathwayBrowser/#/R-SSC-5688797 ATXN3 family cleave Ub chains IEA Sus scrofa A0A287A7D5 R-SSC-8952631 https://reactome.org/PathwayBrowser/#/R-SSC-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A7D5 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287A7D5 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A7D5 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A7D5 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287A7D5 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287A7D5 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287A7D5 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287A7F8 R-SSC-1592240 https://reactome.org/PathwayBrowser/#/R-SSC-1592240 Formation of NRF2 IEA Sus scrofa A0A287A7H5 R-SSC-72095 https://reactome.org/PathwayBrowser/#/R-SSC-72095 Internal Methylation of mRNA IEA Sus scrofa A0A287A7H6 R-SSC-6791221 https://reactome.org/PathwayBrowser/#/R-SSC-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA IEA Sus scrofa A0A287A7H6 R-SSC-6791222 https://reactome.org/PathwayBrowser/#/R-SSC-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Sus scrofa A0A287A7H6 R-SSC-6791227 https://reactome.org/PathwayBrowser/#/R-SSC-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Sus scrofa A0A287A7I4 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A287A7I4 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A287A7I5 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287A7J0 R-SSC-913675 https://reactome.org/PathwayBrowser/#/R-SSC-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Sus scrofa A0A287A7K2 R-SSC-426240 https://reactome.org/PathwayBrowser/#/R-SSC-426240 DAG kinase produces phosphatidic acid from DAG IEA Sus scrofa A0A287A7K4 R-SSC-8955844 https://reactome.org/PathwayBrowser/#/R-SSC-8955844 RBKS phosphorylates ribose to R5P IEA Sus scrofa A0A287A7K9 R-SSC-9865663 https://reactome.org/PathwayBrowser/#/R-SSC-9865663 MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex IEA Sus scrofa A0A287A7L3 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa A0A287A7L3 R-SSC-420127 https://reactome.org/PathwayBrowser/#/R-SSC-420127 CGRP receptor can bind calcitonin gene-related peptides IEA Sus scrofa A0A287A7L3 R-SSC-420214 https://reactome.org/PathwayBrowser/#/R-SSC-420214 The adrenomedullin receptor can bind adrenomedullin and intermedin IEA Sus scrofa A0A287A7L3 R-SSC-9861324 https://reactome.org/PathwayBrowser/#/R-SSC-9861324 ADM:CALCRL:RAMP2:G-alpha(s):GDP:G-beta:G-gamma exchanges GDP for GTP IEA Sus scrofa A0A287A7L3 R-SSC-9861332 https://reactome.org/PathwayBrowser/#/R-SSC-9861332 ADM (Adrenomedullin) binds CALCRL:RAMP2 IEA Sus scrofa A0A287A7L8 R-SSC-388824 https://reactome.org/PathwayBrowser/#/R-SSC-388824 PTPRF, PTPRS, PTPRD bind Liprins IEA Sus scrofa A0A287A7L8 R-SSC-6798258 https://reactome.org/PathwayBrowser/#/R-SSC-6798258 PRTPRF, PTPRS, PTPRD bind LRRC4B IEA Sus scrofa A0A287A7L8 R-SSC-74733 https://reactome.org/PathwayBrowser/#/R-SSC-74733 Insulin receptor de-phosphorylation IEA Sus scrofa A0A287A7Q7 R-SSC-72697 https://reactome.org/PathwayBrowser/#/R-SSC-72697 Start codon recognition IEA Sus scrofa A0A287A7S8 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287A7S8 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287A7S8 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287A7S8 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287A7S8 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287A7S8 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287A7S8 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287A7S8 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287A7S8 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287A7S8 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287A7S8 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287A7S8 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287A7S8 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287A7S8 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287A7S8 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287A7S8 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287A7S8 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287A7S8 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287A7S8 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287A7S8 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287A7S8 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287A7S8 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287A7S8 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287A7S8 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287A7S8 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287A7S8 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287A7S8 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287A7S8 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287A7S8 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287A7S8 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287A7S8 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287A7S8 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287A7S8 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287A7S8 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287A7S8 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287A7S8 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287A7S8 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287A7S8 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287A7S8 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287A7S8 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287A7S8 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287A7S8 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287A7S8 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287A7S8 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287A7S8 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287A7S8 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287A7S8 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287A7U1 R-SSC-5683735 https://reactome.org/PathwayBrowser/#/R-SSC-5683735 CHEK2 is recruited to DNA DSBs IEA Sus scrofa A0A287A7U1 R-SSC-5683774 https://reactome.org/PathwayBrowser/#/R-SSC-5683774 p-T68-CHEK2 dimerizes IEA Sus scrofa A0A287A7U1 R-SSC-5683792 https://reactome.org/PathwayBrowser/#/R-SSC-5683792 p-T68-CHEK2 autophosphorylates IEA Sus scrofa A0A287A7U1 R-SSC-5683801 https://reactome.org/PathwayBrowser/#/R-SSC-5683801 CHEK2 phosphorylates BRCA1 IEA Sus scrofa A0A287A7U1 R-SSC-6804266 https://reactome.org/PathwayBrowser/#/R-SSC-6804266 CHEK2 phosphorylates TTC5 IEA Sus scrofa A0A287A7U1 R-SSC-69608 https://reactome.org/PathwayBrowser/#/R-SSC-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Sus scrofa A0A287A7U1 R-SSC-69685 https://reactome.org/PathwayBrowser/#/R-SSC-69685 CHEK2 phosphorylates TP53 IEA Sus scrofa A0A287A7U1 R-SSC-69891 https://reactome.org/PathwayBrowser/#/R-SSC-69891 Phosphorylation and activation of CHEK2 by ATM IEA Sus scrofa A0A287A7U1 R-SSC-75809 https://reactome.org/PathwayBrowser/#/R-SSC-75809 Phosphorylation of Cdc25C at Ser216 by CHEK2 IEA Sus scrofa A0A287A7V3 R-SSC-1605595 https://reactome.org/PathwayBrowser/#/R-SSC-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Sus scrofa A0A287A7V3 R-SSC-1605632 https://reactome.org/PathwayBrowser/#/R-SSC-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Sus scrofa A0A287A7V3 R-SSC-1638053 https://reactome.org/PathwayBrowser/#/R-SSC-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Sus scrofa A0A287A7V3 R-SSC-2105001 https://reactome.org/PathwayBrowser/#/R-SSC-2105001 HEXA cleaves the terminal GalNAc from DS IEA Sus scrofa A0A287A7V3 R-SSC-2162225 https://reactome.org/PathwayBrowser/#/R-SSC-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Sus scrofa A0A287A7V3 R-SSC-9840833 https://reactome.org/PathwayBrowser/#/R-SSC-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Sus scrofa A0A287A7V3 R-SSC-9840884 https://reactome.org/PathwayBrowser/#/R-SSC-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Sus scrofa A0A287A7V4 R-SSC-3858489 https://reactome.org/PathwayBrowser/#/R-SSC-3858489 ppDVL binds DAAM1 IEA Sus scrofa A0A287A7V4 R-SSC-3858495 https://reactome.org/PathwayBrowser/#/R-SSC-3858495 DAAM1 recruits GTP-bound RHOA IEA Sus scrofa A0A287A7V4 R-SSC-3965450 https://reactome.org/PathwayBrowser/#/R-SSC-3965450 DAAM1 recruits PFN1 IEA Sus scrofa A0A287A7V4 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa A0A287A7V4 R-SSC-9013024 https://reactome.org/PathwayBrowser/#/R-SSC-9013024 RHOB binds effectors at the plasma membrane IEA Sus scrofa A0A287A7V4 R-SSC-9013110 https://reactome.org/PathwayBrowser/#/R-SSC-9013110 RHOC binds effectors at the plasma membrane IEA Sus scrofa A0A287A7V4 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A287A7V7 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287A7X1 R-SSC-1253282 https://reactome.org/PathwayBrowser/#/R-SSC-1253282 ERBB4 ubiquitination by WWP1/ITCH IEA Sus scrofa A0A287A7X1 R-SSC-1253300 https://reactome.org/PathwayBrowser/#/R-SSC-1253300 ERBB4 binds WWP1/ITCH ubiquitin ligases IEA Sus scrofa A0A287A7X1 R-SSC-1912357 https://reactome.org/PathwayBrowser/#/R-SSC-1912357 ITCH ubiquitinates DTX IEA Sus scrofa A0A287A7X1 R-SSC-1980125 https://reactome.org/PathwayBrowser/#/R-SSC-1980125 ITCH binds DTX IEA Sus scrofa A0A287A7X1 R-SSC-5610735 https://reactome.org/PathwayBrowser/#/R-SSC-5610735 NUMB binds ITCH IEA Sus scrofa A0A287A7X1 R-SSC-5610737 https://reactome.org/PathwayBrowser/#/R-SSC-5610737 NUMB:ITCH bind and ubiquitnate GLI1 IEA Sus scrofa A0A287A7X1 R-SSC-5610760 https://reactome.org/PathwayBrowser/#/R-SSC-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Sus scrofa A0A287A7X1 R-SSC-5635861 https://reactome.org/PathwayBrowser/#/R-SSC-5635861 NUMB:ITCH binds GLI1 IEA Sus scrofa A0A287A7X1 R-SSC-5635864 https://reactome.org/PathwayBrowser/#/R-SSC-5635864 NUMB:ITCH ubiquitinates GLI1 IEA Sus scrofa A0A287A7X1 R-SSC-5635868 https://reactome.org/PathwayBrowser/#/R-SSC-5635868 ub-GLI is degraded by the proteasome IEA Sus scrofa A0A287A7X1 R-SSC-8956684 https://reactome.org/PathwayBrowser/#/R-SSC-8956684 ITCH polyubiquitinates TP73 IEA Sus scrofa A0A287A7X1 R-SSC-9793444 https://reactome.org/PathwayBrowser/#/R-SSC-9793444 ITCH polyubiquitinates MLKL at K50 IEA Sus scrofa A0A287A7X1 R-SSC-9793451 https://reactome.org/PathwayBrowser/#/R-SSC-9793451 MLKL binds ITCH IEA Sus scrofa A0A287A7X1 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287A7X1 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287A7X1 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287A7X1 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287A7Z4 R-SSC-622326 https://reactome.org/PathwayBrowser/#/R-SSC-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Sus scrofa A0A287A7Z4 R-SSC-629595 https://reactome.org/PathwayBrowser/#/R-SSC-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Sus scrofa A0A287A7Z4 R-SSC-629596 https://reactome.org/PathwayBrowser/#/R-SSC-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Sus scrofa A0A287A7Z4 R-SSC-629599 https://reactome.org/PathwayBrowser/#/R-SSC-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Sus scrofa A0A287A808 R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa A0A287A808 R-SSC-9709406 https://reactome.org/PathwayBrowser/#/R-SSC-9709406 CO binds to Cytochrome c oxidase IEA Sus scrofa A0A287A808 R-SSC-9865663 https://reactome.org/PathwayBrowser/#/R-SSC-9865663 MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex IEA Sus scrofa A0A287A809 R-SSC-8854302 https://reactome.org/PathwayBrowser/#/R-SSC-8854302 TBC1D7 binds the TSC1-TSC2 complex IEA Sus scrofa A0A287A814 R-SSC-176956 https://reactome.org/PathwayBrowser/#/R-SSC-176956 Formation of GINS complex IEA Sus scrofa A0A287A819 R-SSC-1247960 https://reactome.org/PathwayBrowser/#/R-SSC-1247960 Activation of p38 MAPK IEA Sus scrofa A0A287A819 R-SSC-5218804 https://reactome.org/PathwayBrowser/#/R-SSC-5218804 p38 MAPK activation by VEGFR IEA Sus scrofa A0A287A835 R-SSC-75885 https://reactome.org/PathwayBrowser/#/R-SSC-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Sus scrofa A0A287A835 R-SSC-8849345 https://reactome.org/PathwayBrowser/#/R-SSC-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine IEA Sus scrofa A0A287A853 R-SSC-114544 https://reactome.org/PathwayBrowser/#/R-SSC-114544 p115-RhoGEF activation of RHOA IEA Sus scrofa A0A287A853 R-SSC-114548 https://reactome.org/PathwayBrowser/#/R-SSC-114548 G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) IEA Sus scrofa A0A287A853 R-SSC-114552 https://reactome.org/PathwayBrowser/#/R-SSC-114552 Thrombin-activated PARs activate G12/13 IEA Sus scrofa A0A287A853 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa A0A287A853 R-SSC-397891 https://reactome.org/PathwayBrowser/#/R-SSC-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Sus scrofa A0A287A853 R-SSC-398184 https://reactome.org/PathwayBrowser/#/R-SSC-398184 LARG activation by G alpha 12/13 IEA Sus scrofa A0A287A853 R-SSC-398185 https://reactome.org/PathwayBrowser/#/R-SSC-398185 LARG binds plexin B1 IEA Sus scrofa A0A287A853 R-SSC-418574 https://reactome.org/PathwayBrowser/#/R-SSC-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Sus scrofa A0A287A853 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa A0A287A853 R-SSC-428909 https://reactome.org/PathwayBrowser/#/R-SSC-428909 Activated TP receptor binds G-protein G13 IEA Sus scrofa A0A287A853 R-SSC-428917 https://reactome.org/PathwayBrowser/#/R-SSC-428917 G13 activation by TP receptor IEA Sus scrofa A0A287A853 R-SSC-428918 https://reactome.org/PathwayBrowser/#/R-SSC-428918 Dissociation of the TP:G13 complex IEA Sus scrofa A0A287A853 R-SSC-751019 https://reactome.org/PathwayBrowser/#/R-SSC-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Sus scrofa A0A287A853 R-SSC-751027 https://reactome.org/PathwayBrowser/#/R-SSC-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Sus scrofa A0A287A853 R-SSC-751029 https://reactome.org/PathwayBrowser/#/R-SSC-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Sus scrofa A0A287A853 R-SSC-751039 https://reactome.org/PathwayBrowser/#/R-SSC-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Sus scrofa A0A287A853 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A287A853 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa A0A287A864 R-SSC-190245 https://reactome.org/PathwayBrowser/#/R-SSC-190245 FGFR1b binds to FGF IEA Sus scrofa A0A287A864 R-SSC-190256 https://reactome.org/PathwayBrowser/#/R-SSC-190256 FGFR1c binds to FGF IEA Sus scrofa A0A287A864 R-SSC-9839381 https://reactome.org/PathwayBrowser/#/R-SSC-9839381 FGF2:TGFBR3 binding to GIPC1 IEA Sus scrofa A0A287A864 R-SSC-9839401 https://reactome.org/PathwayBrowser/#/R-SSC-9839401 TGFBR3 degradation IEA Sus scrofa A0A287A864 R-SSC-9839402 https://reactome.org/PathwayBrowser/#/R-SSC-9839402 TGFBR3 binding to GIPC1 IEA Sus scrofa A0A287A869 R-SSC-2130619 https://reactome.org/PathwayBrowser/#/R-SSC-2130619 TGN-lysosomal vesicle coat assembly IEA Sus scrofa A0A287A869 R-SSC-2130641 https://reactome.org/PathwayBrowser/#/R-SSC-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Sus scrofa A0A287A869 R-SSC-2130725 https://reactome.org/PathwayBrowser/#/R-SSC-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Sus scrofa A0A287A869 R-SSC-2201293 https://reactome.org/PathwayBrowser/#/R-SSC-2201293 Endocytosis of TLR4:LY96:LPS:CD14 IEA Sus scrofa A0A287A869 R-SSC-555065 https://reactome.org/PathwayBrowser/#/R-SSC-555065 Formation of clathrin coated vesicle IEA Sus scrofa A0A287A869 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287A869 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287A869 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287A869 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287A869 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287A869 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287A869 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287A869 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287A869 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287A869 R-SSC-8951498 https://reactome.org/PathwayBrowser/#/R-SSC-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Sus scrofa A0A287A892 R-SSC-6781797 https://reactome.org/PathwayBrowser/#/R-SSC-6781797 USP19 binds HIF1A,BIRC2,BIRC3 IEA Sus scrofa A0A287A892 R-SSC-6781814 https://reactome.org/PathwayBrowser/#/R-SSC-6781814 USP19 deubiquitinates RNF123 IEA Sus scrofa A0A287A8A9 R-SSC-2559456 https://reactome.org/PathwayBrowser/#/R-SSC-2559456 TIRAP binds PIP2-rich regions in the plasma membrane IEA Sus scrofa A0A287A8C7 R-SSC-201637 https://reactome.org/PathwayBrowser/#/R-SSC-201637 Caspase-mediated cleavage of plectin-1 IEA Sus scrofa A0A287A8C7 R-SSC-2213192 https://reactome.org/PathwayBrowser/#/R-SSC-2213192 Hemidesmosome formation IEA Sus scrofa A0A287A8C7 R-SSC-432909 https://reactome.org/PathwayBrowser/#/R-SSC-432909 Interaction of Plectin with Integrin beta 4 IEA Sus scrofa A0A287A8C7 R-SSC-432952 https://reactome.org/PathwayBrowser/#/R-SSC-432952 BP180 interacts intracellularly with plectin and integrin beta4 IEA Sus scrofa A0A287A8C7 R-SSC-432956 https://reactome.org/PathwayBrowser/#/R-SSC-432956 BP230 is recruited to the hemidesmosome IEA Sus scrofa A0A287A8C7 R-SSC-446077 https://reactome.org/PathwayBrowser/#/R-SSC-446077 BP230 interacts with keretin K5/K14 IEA Sus scrofa A0A287A8C7 R-SSC-446083 https://reactome.org/PathwayBrowser/#/R-SSC-446083 CD151 interacts with BP180 and the integrin alpha 6 subunit IEA Sus scrofa A0A287A8C8 R-SSC-428585 https://reactome.org/PathwayBrowser/#/R-SSC-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Sus scrofa A0A287A8E1 R-SSC-2130619 https://reactome.org/PathwayBrowser/#/R-SSC-2130619 TGN-lysosomal vesicle coat assembly IEA Sus scrofa A0A287A8E1 R-SSC-2130641 https://reactome.org/PathwayBrowser/#/R-SSC-2130641 Translocation of TGN-lysosome vesicle to lysosome IEA Sus scrofa A0A287A8E1 R-SSC-2213236 https://reactome.org/PathwayBrowser/#/R-SSC-2213236 TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome IEA Sus scrofa A0A287A8E1 R-SSC-421831 https://reactome.org/PathwayBrowser/#/R-SSC-421831 trans-Golgi Network Coat Assembly IEA Sus scrofa A0A287A8E1 R-SSC-421835 https://reactome.org/PathwayBrowser/#/R-SSC-421835 trans-Golgi Network Vesicle Scission IEA Sus scrofa A0A287A8E1 R-SSC-432706 https://reactome.org/PathwayBrowser/#/R-SSC-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Sus scrofa A0A287A8E1 R-SSC-432707 https://reactome.org/PathwayBrowser/#/R-SSC-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Sus scrofa A0A287A8E1 R-SSC-5333658 https://reactome.org/PathwayBrowser/#/R-SSC-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 IEA Sus scrofa A0A287A8E1 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A287A8E1 R-SSC-8951498 https://reactome.org/PathwayBrowser/#/R-SSC-8951498 Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex IEA Sus scrofa A0A287A8F1 R-SSC-9693250 https://reactome.org/PathwayBrowser/#/R-SSC-9693250 RHOD binds effectors at the Golgi membrane IEA Sus scrofa A0A287A8H2 R-SSC-9639287 https://reactome.org/PathwayBrowser/#/R-SSC-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Sus scrofa A0A287A8H2 R-SSC-9640195 https://reactome.org/PathwayBrowser/#/R-SSC-9640195 RRAGA,B hydrolyzes GTP IEA Sus scrofa A0A287A8H2 R-SSC-9640237 https://reactome.org/PathwayBrowser/#/R-SSC-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Sus scrofa A0A287A8H2 R-SSC-9657619 https://reactome.org/PathwayBrowser/#/R-SSC-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 IEA Sus scrofa A0A287A8H4 R-SSC-2076611 https://reactome.org/PathwayBrowser/#/R-SSC-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Sus scrofa A0A287A8H7 R-SSC-1855165 https://reactome.org/PathwayBrowser/#/R-SSC-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa A0A287A8H7 R-SSC-1855166 https://reactome.org/PathwayBrowser/#/R-SSC-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Sus scrofa A0A287A8H7 R-SSC-1855198 https://reactome.org/PathwayBrowser/#/R-SSC-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa A0A287A8H7 R-SSC-2023971 https://reactome.org/PathwayBrowser/#/R-SSC-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa A0A287A8H7 R-SSC-2023973 https://reactome.org/PathwayBrowser/#/R-SSC-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa A0A287A8I8 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287A8I8 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287A8I8 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287A8I8 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287A8I8 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287A8I8 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287A8J7 R-SSC-111742 https://reactome.org/PathwayBrowser/#/R-SSC-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa A0A287A8J7 R-SSC-111751 https://reactome.org/PathwayBrowser/#/R-SSC-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa A0A287A8J7 R-SSC-111804 https://reactome.org/PathwayBrowser/#/R-SSC-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa A0A287A8J7 R-SSC-8866405 https://reactome.org/PathwayBrowser/#/R-SSC-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa A0A287A8K6 R-SSC-5676637 https://reactome.org/PathwayBrowser/#/R-SSC-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Sus scrofa A0A287A8K9 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A8K9 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287A8K9 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A8K9 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A8K9 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A8K9 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287A8K9 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287A8K9 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287A8K9 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287A8L0 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A8L0 R-SSC-8952626 https://reactome.org/PathwayBrowser/#/R-SSC-8952626 AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A8L0 R-SSC-8952631 https://reactome.org/PathwayBrowser/#/R-SSC-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A8L0 R-SSC-8952638 https://reactome.org/PathwayBrowser/#/R-SSC-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A8L0 R-SSC-8955285 https://reactome.org/PathwayBrowser/#/R-SSC-8955285 COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A8L0 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A8L0 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A8L0 R-SSC-8956045 https://reactome.org/PathwayBrowser/#/R-SSC-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A8L0 R-SSC-8956099 https://reactome.org/PathwayBrowser/#/R-SSC-8956099 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 IEA Sus scrofa A0A287A8L0 R-SSC-8956103 https://reactome.org/PathwayBrowser/#/R-SSC-8956103 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha IEA Sus scrofa A0A287A8L0 R-SSC-8956106 https://reactome.org/PathwayBrowser/#/R-SSC-8956106 VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha IEA Sus scrofa A0A287A8L0 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A8L0 R-SSC-9755303 https://reactome.org/PathwayBrowser/#/R-SSC-9755303 26S proteasome degrades HIFalpha IEA Sus scrofa A0A287A8N2 R-SSC-5693691 https://reactome.org/PathwayBrowser/#/R-SSC-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Sus scrofa A0A287A8N2 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa A0A287A8N2 R-SSC-9727567 https://reactome.org/PathwayBrowser/#/R-SSC-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Sus scrofa A0A287A8N2 R-SSC-9749792 https://reactome.org/PathwayBrowser/#/R-SSC-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Sus scrofa A0A287A8P0 R-SSC-5362412 https://reactome.org/PathwayBrowser/#/R-SSC-5362412 SYVN1 ubiquitinates Hh C-terminal fragments IEA Sus scrofa A0A287A8P0 R-SSC-5362437 https://reactome.org/PathwayBrowser/#/R-SSC-5362437 C-terminal Hh fragments are bound by lectins IEA Sus scrofa A0A287A8P0 R-SSC-5362441 https://reactome.org/PathwayBrowser/#/R-SSC-5362441 C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane IEA Sus scrofa A0A287A8P0 R-SSC-5362459 https://reactome.org/PathwayBrowser/#/R-SSC-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Sus scrofa A0A287A8P0 R-SSC-8866542 https://reactome.org/PathwayBrowser/#/R-SSC-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Sus scrofa A0A287A8P0 R-SSC-8866546 https://reactome.org/PathwayBrowser/#/R-SSC-8866546 RNF5 and RNF185 ubiquitinate misfolded CFTR IEA Sus scrofa A0A287A8P0 R-SSC-8866551 https://reactome.org/PathwayBrowser/#/R-SSC-8866551 CFTR binds components of the ERAD machinery for ubiquitination and degradation IEA Sus scrofa A0A287A8Q7 R-SSC-5655466 https://reactome.org/PathwayBrowser/#/R-SSC-5655466 USP1:WDR48 deubiquitinates monoUb:K164-PCNA IEA Sus scrofa A0A287A8Q7 R-SSC-5655481 https://reactome.org/PathwayBrowser/#/R-SSC-5655481 USP1:WDR48 binds monoUb:K164-PCNA IEA Sus scrofa A0A287A8Q7 R-SSC-5655483 https://reactome.org/PathwayBrowser/#/R-SSC-5655483 USP1 autocleavage IEA Sus scrofa A0A287A8Q7 R-SSC-6785732 https://reactome.org/PathwayBrowser/#/R-SSC-6785732 DNA nucleases bind monoubiquitinated ID2 complex IEA Sus scrofa A0A287A8Q7 R-SSC-6786171 https://reactome.org/PathwayBrowser/#/R-SSC-6786171 FANCD2 deubiquitination by USP1:WDR48 IEA Sus scrofa A0A287A8Q8 R-SSC-8850777 https://reactome.org/PathwayBrowser/#/R-SSC-8850777 SPINK6 binds KLK14 IEA Sus scrofa A0A287A8Q8 R-SSC-8850786 https://reactome.org/PathwayBrowser/#/R-SSC-8850786 SPINK6 binds KLK12 IEA Sus scrofa A0A287A8Q8 R-SSC-8850794 https://reactome.org/PathwayBrowser/#/R-SSC-8850794 SPINK6 binds KLK5 IEA Sus scrofa A0A287A8R7 R-SSC-6795290 https://reactome.org/PathwayBrowser/#/R-SSC-6795290 TORC2 complex phosphorylates SGK1 IEA Sus scrofa A0A287A8R8 R-SSC-8981637 https://reactome.org/PathwayBrowser/#/R-SSC-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Sus scrofa A0A287A8S7 R-SSC-176264 https://reactome.org/PathwayBrowser/#/R-SSC-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Sus scrofa A0A287A8S7 R-SSC-5684882 https://reactome.org/PathwayBrowser/#/R-SSC-5684882 CHEK1 is recruited to resected DNA DSBs IEA Sus scrofa A0A287A8S7 R-SSC-5684887 https://reactome.org/PathwayBrowser/#/R-SSC-5684887 Activation of CHEK1 at resected DNA DSBs IEA Sus scrofa A0A287A8S7 R-SSC-5685011 https://reactome.org/PathwayBrowser/#/R-SSC-5685011 ATR activation at DNA DSBs IEA Sus scrofa A0A287A8S7 R-SSC-5685156 https://reactome.org/PathwayBrowser/#/R-SSC-5685156 ATR phosphorylates RPA2 IEA Sus scrofa A0A287A8S7 R-SSC-5686642 https://reactome.org/PathwayBrowser/#/R-SSC-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Sus scrofa A0A287A8S7 R-SSC-5686657 https://reactome.org/PathwayBrowser/#/R-SSC-5686657 ERCC1:XPF cleaves flaps generated by SSA IEA Sus scrofa A0A287A8S7 R-SSC-5693564 https://reactome.org/PathwayBrowser/#/R-SSC-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Sus scrofa A0A287A8S7 R-SSC-5693580 https://reactome.org/PathwayBrowser/#/R-SSC-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Sus scrofa A0A287A8S7 R-SSC-6799332 https://reactome.org/PathwayBrowser/#/R-SSC-6799332 ATR phosphorylates TP53 IEA Sus scrofa A0A287A8T2 R-SSC-5626938 https://reactome.org/PathwayBrowser/#/R-SSC-5626938 Beta-catenin binds SOX proteins IEA Sus scrofa A0A287A8U2 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287A8W2 R-SSC-5649658 https://reactome.org/PathwayBrowser/#/R-SSC-5649658 NEIL1 cleaves DHU from damaged DNA IEA Sus scrofa A0A287A8W2 R-SSC-5649664 https://reactome.org/PathwayBrowser/#/R-SSC-5649664 NEIL1 cleaves FapyG from damaged DNA IEA Sus scrofa A0A287A8W2 R-SSC-5649673 https://reactome.org/PathwayBrowser/#/R-SSC-5649673 NEIL1 cleaves FapyA from damaged DNA IEA Sus scrofa A0A287A8W2 R-SSC-5649705 https://reactome.org/PathwayBrowser/#/R-SSC-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Sus scrofa A0A287A8W2 R-SSC-5649708 https://reactome.org/PathwayBrowser/#/R-SSC-5649708 NEIL1,NEIL2 recruits POLB to incised AP site IEA Sus scrofa A0A287A8W2 R-SSC-5649711 https://reactome.org/PathwayBrowser/#/R-SSC-5649711 NEIL1,NEIL2 incises DNA strand 5' to the AP site IEA Sus scrofa A0A287A8W2 R-SSC-5649723 https://reactome.org/PathwayBrowser/#/R-SSC-5649723 POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution IEA Sus scrofa A0A287A8W2 R-SSC-5649725 https://reactome.org/PathwayBrowser/#/R-SSC-5649725 POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) IEA Sus scrofa A0A287A8W2 R-SSC-5649726 https://reactome.org/PathwayBrowser/#/R-SSC-5649726 LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA IEA Sus scrofa A0A287A8W2 R-SSC-5649734 https://reactome.org/PathwayBrowser/#/R-SSC-5649734 LIG3 ligates NEIL1,NEIL2-generated single strand break IEA Sus scrofa A0A287A8W2 R-SSC-9629149 https://reactome.org/PathwayBrowser/#/R-SSC-9629149 NEIL1 cleaves thymine glycol from damaged DNA IEA Sus scrofa A0A287A8W2 R-SSC-9629918 https://reactome.org/PathwayBrowser/#/R-SSC-9629918 NEIL1 translocates to the nucleus IEA Sus scrofa A0A287A8W6 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa A0A287A8Z7 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A287A8Z7 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A287A8Z7 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A287A8Z7 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A287A8Z7 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A287A8Z7 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A287A8Z7 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A287A8Z7 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A287A8Z7 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A287A8Z7 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287A8Z7 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A287A8Z7 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A287A8Z7 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287A8Z7 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A287A8Z7 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287A8Z7 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287A8Z7 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287A8Z7 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287A8Z7 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287A8Z7 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A287A8Z7 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A287A907 R-SSC-192157 https://reactome.org/PathwayBrowser/#/R-SSC-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Sus scrofa A0A287A907 R-SSC-193709 https://reactome.org/PathwayBrowser/#/R-SSC-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Sus scrofa A0A287A907 R-SSC-193845 https://reactome.org/PathwayBrowser/#/R-SSC-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Sus scrofa A0A287A907 R-SSC-76496 https://reactome.org/PathwayBrowser/#/R-SSC-76496 PTGIS, CYP8A1 isomerise PGH2 to PGI2 IEA Sus scrofa A0A287A913 R-SSC-5159245 https://reactome.org/PathwayBrowser/#/R-SSC-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Sus scrofa A0A287A913 R-SSC-5244692 https://reactome.org/PathwayBrowser/#/R-SSC-5244692 Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) IEA Sus scrofa A0A287A913 R-SSC-5637686 https://reactome.org/PathwayBrowser/#/R-SSC-5637686 WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) IEA Sus scrofa A0A287A913 R-SSC-8936481 https://reactome.org/PathwayBrowser/#/R-SSC-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Sus scrofa A0A287A913 R-SSC-8936621 https://reactome.org/PathwayBrowser/#/R-SSC-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Sus scrofa A0A287A913 R-SSC-8937016 https://reactome.org/PathwayBrowser/#/R-SSC-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Sus scrofa A0A287A913 R-SSC-8937050 https://reactome.org/PathwayBrowser/#/R-SSC-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Sus scrofa A0A287A913 R-SSC-9676254 https://reactome.org/PathwayBrowser/#/R-SSC-9676254 Formation of the MLL3 complex IEA Sus scrofa A0A287A929 R-SSC-2161961 https://reactome.org/PathwayBrowser/#/R-SSC-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Sus scrofa A0A287A929 R-SSC-9024993 https://reactome.org/PathwayBrowser/#/R-SSC-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Sus scrofa A0A287A929 R-SSC-9033235 https://reactome.org/PathwayBrowser/#/R-SSC-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A287A929 R-SSC-9033236 https://reactome.org/PathwayBrowser/#/R-SSC-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Sus scrofa A0A287A929 R-SSC-9915968 https://reactome.org/PathwayBrowser/#/R-SSC-9915968 8,9-EET is hydrolysed to 8.9-DHET by EPHX2 IEA Sus scrofa A0A287A929 R-SSC-9915986 https://reactome.org/PathwayBrowser/#/R-SSC-9915986 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 IEA Sus scrofa A0A287A929 R-SSC-9915994 https://reactome.org/PathwayBrowser/#/R-SSC-9915994 14,15-EET is hydrolysed to 14,15-DHET by EPHX2 IEA Sus scrofa A0A287A935 R-SSC-5251942 https://reactome.org/PathwayBrowser/#/R-SSC-5251942 Hikeshi binds HSP70s:ATP IEA Sus scrofa A0A287A935 R-SSC-5251955 https://reactome.org/PathwayBrowser/#/R-SSC-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Sus scrofa A0A287A935 R-SSC-5251959 https://reactome.org/PathwayBrowser/#/R-SSC-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Sus scrofa A0A287A935 R-SSC-5252041 https://reactome.org/PathwayBrowser/#/R-SSC-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Sus scrofa A0A287A935 R-SSC-5252079 https://reactome.org/PathwayBrowser/#/R-SSC-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Sus scrofa A0A287A948 R-SSC-448632 https://reactome.org/PathwayBrowser/#/R-SSC-448632 IL34 dimerizes IEA Sus scrofa A0A287A948 R-SSC-6787820 https://reactome.org/PathwayBrowser/#/R-SSC-6787820 IL34 dimer binds CSF1R IEA Sus scrofa A0A287A948 R-SSC-8981657 https://reactome.org/PathwayBrowser/#/R-SSC-8981657 IL34 dimer binds PTPRZ1 IEA Sus scrofa A0A287A948 R-SSC-9009485 https://reactome.org/PathwayBrowser/#/R-SSC-9009485 IL34:CSF1 binds CSF1R IEA Sus scrofa A0A287A948 R-SSC-9009488 https://reactome.org/PathwayBrowser/#/R-SSC-9009488 IL34 binds CSF1 IEA Sus scrofa A0A287A948 R-SSC-9009554 https://reactome.org/PathwayBrowser/#/R-SSC-9009554 IL34 dimer:SDC1 binds CSF1R IEA Sus scrofa A0A287A948 R-SSC-9009558 https://reactome.org/PathwayBrowser/#/R-SSC-9009558 IL34 dimer binds SDC1 IEA Sus scrofa A0A287A959 R-SSC-2327738 https://reactome.org/PathwayBrowser/#/R-SSC-2327738 DDR1 binds collagen type I, II, III, IV, V, XI fibrils IEA Sus scrofa A0A287A962 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A962 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287A962 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A962 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A962 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A962 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287A962 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287A962 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287A962 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287A969 R-SSC-5656070 https://reactome.org/PathwayBrowser/#/R-SSC-5656070 FGFBPs bind FGFs IEA Sus scrofa A0A287A976 R-SSC-6781833 https://reactome.org/PathwayBrowser/#/R-SSC-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Sus scrofa A0A287A976 R-SSC-8863721 https://reactome.org/PathwayBrowser/#/R-SSC-8863721 NEDD8-STON binds TOR1 hexamer and COP9 complex IEA Sus scrofa A0A287A976 R-SSC-8863723 https://reactome.org/PathwayBrowser/#/R-SSC-8863723 COP9 and TOR1 deneddylate STON2 IEA Sus scrofa A0A287A976 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A976 R-SSC-8956045 https://reactome.org/PathwayBrowser/#/R-SSC-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A9C4 R-SSC-1226094 https://reactome.org/PathwayBrowser/#/R-SSC-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Sus scrofa A0A287A9C4 R-SSC-1226095 https://reactome.org/PathwayBrowser/#/R-SSC-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Sus scrofa A0A287A9C4 R-SSC-187520 https://reactome.org/PathwayBrowser/#/R-SSC-187520 Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 IEA Sus scrofa A0A287A9C4 R-SSC-187916 https://reactome.org/PathwayBrowser/#/R-SSC-187916 Cyclin A:Cdk2 mediated phosphorylation of p27/p21 IEA Sus scrofa A0A287A9C4 R-SSC-187934 https://reactome.org/PathwayBrowser/#/R-SSC-187934 Inactivation of Cyclin A:Cdk2 complexes by p27/p21 IEA Sus scrofa A0A287A9C4 R-SSC-3788705 https://reactome.org/PathwayBrowser/#/R-SSC-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Sus scrofa A0A287A9C4 R-SSC-3788708 https://reactome.org/PathwayBrowser/#/R-SSC-3788708 CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 IEA Sus scrofa A0A287A9C4 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa A0A287A9C4 R-SSC-69562 https://reactome.org/PathwayBrowser/#/R-SSC-69562 Inactivation of Cyclin E:Cdk2 complexes by p27/p21 IEA Sus scrofa A0A287A9C4 R-SSC-8941915 https://reactome.org/PathwayBrowser/#/R-SSC-8941915 Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes IEA Sus scrofa A0A287A9C4 R-SSC-8942607 https://reactome.org/PathwayBrowser/#/R-SSC-8942607 Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes IEA Sus scrofa A0A287A9C4 R-SSC-8942803 https://reactome.org/PathwayBrowser/#/R-SSC-8942803 Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus IEA Sus scrofa A0A287A9C4 R-SSC-8942836 https://reactome.org/PathwayBrowser/#/R-SSC-8942836 CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 IEA Sus scrofa A0A287A9C4 R-SSC-9018017 https://reactome.org/PathwayBrowser/#/R-SSC-9018017 RB1 binds and inhibits E2F1/2/3:DP1/2 complexes IEA Sus scrofa A0A287A9C5 R-SSC-2186607 https://reactome.org/PathwayBrowser/#/R-SSC-2186607 TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer IEA Sus scrofa A0A287A9D2 R-SSC-376419 https://reactome.org/PathwayBrowser/#/R-SSC-376419 Formation of NR-MED1 Coactivator Complex IEA Sus scrofa A0A287A9D2 R-SSC-382096 https://reactome.org/PathwayBrowser/#/R-SSC-382096 Formation of NR-NCOR Corepressor Complex IEA Sus scrofa A0A287A9E2 R-SSC-199518 https://reactome.org/PathwayBrowser/#/R-SSC-199518 C3d-complexed antigen binds to complement receptor IEA Sus scrofa A0A287A9G3 R-SSC-3965444 https://reactome.org/PathwayBrowser/#/R-SSC-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Sus scrofa A0A287A9G3 R-SSC-3965447 https://reactome.org/PathwayBrowser/#/R-SSC-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Sus scrofa A0A287A9G4 R-SSC-70577 https://reactome.org/PathwayBrowser/#/R-SSC-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Sus scrofa A0A287A9H4 R-SSC-72103 https://reactome.org/PathwayBrowser/#/R-SSC-72103 Formation of pre-mRNPs IEA Sus scrofa A0A287A9H4 R-SSC-9770119 https://reactome.org/PathwayBrowser/#/R-SSC-9770119 Formation of the Spliceosomal E complex IEA Sus scrofa A0A287A9H4 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A287A9H4 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287A9H4 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A287A9H4 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A287A9J3 R-SSC-6781833 https://reactome.org/PathwayBrowser/#/R-SSC-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Sus scrofa A0A287A9J3 R-SSC-8863721 https://reactome.org/PathwayBrowser/#/R-SSC-8863721 NEDD8-STON binds TOR1 hexamer and COP9 complex IEA Sus scrofa A0A287A9J3 R-SSC-8863723 https://reactome.org/PathwayBrowser/#/R-SSC-8863723 COP9 and TOR1 deneddylate STON2 IEA Sus scrofa A0A287A9J3 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287A9J3 R-SSC-8956045 https://reactome.org/PathwayBrowser/#/R-SSC-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287A9J8 R-SSC-6798739 https://reactome.org/PathwayBrowser/#/R-SSC-6798739 Exocytosis of azurophil granule membrane proteins IEA Sus scrofa A0A287A9M0 R-SSC-445797 https://reactome.org/PathwayBrowser/#/R-SSC-445797 MYLK (MLCK) Active Calmodulin Binding IEA Sus scrofa A0A287A9M0 R-SSC-445813 https://reactome.org/PathwayBrowser/#/R-SSC-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Sus scrofa A0A287A9M0 R-SSC-5668984 https://reactome.org/PathwayBrowser/#/R-SSC-5668984 PAK1 or PAK2 phosphorylates MYLK IEA Sus scrofa A0A287A9P4 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A287A9P4 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A287A9P4 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A287A9P4 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A287A9P4 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287A9P4 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287A9P4 R-SSC-195251 https://reactome.org/PathwayBrowser/#/R-SSC-195251 Assembly of the destruction complex IEA Sus scrofa A0A287A9P4 R-SSC-195275 https://reactome.org/PathwayBrowser/#/R-SSC-195275 Phosphorylation of APC component of the destruction complex IEA Sus scrofa A0A287A9P4 R-SSC-195280 https://reactome.org/PathwayBrowser/#/R-SSC-195280 Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex IEA Sus scrofa A0A287A9P4 R-SSC-195283 https://reactome.org/PathwayBrowser/#/R-SSC-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Sus scrofa A0A287A9P4 R-SSC-195287 https://reactome.org/PathwayBrowser/#/R-SSC-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Sus scrofa A0A287A9P4 R-SSC-195300 https://reactome.org/PathwayBrowser/#/R-SSC-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Sus scrofa A0A287A9P4 R-SSC-195304 https://reactome.org/PathwayBrowser/#/R-SSC-195304 Association of beta-catenin with the destruction complex IEA Sus scrofa A0A287A9P4 R-SSC-195318 https://reactome.org/PathwayBrowser/#/R-SSC-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Sus scrofa A0A287A9P4 R-SSC-201685 https://reactome.org/PathwayBrowser/#/R-SSC-201685 Beta-catenin is released from the destruction complex IEA Sus scrofa A0A287A9P4 R-SSC-2130279 https://reactome.org/PathwayBrowser/#/R-SSC-2130279 Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex IEA Sus scrofa A0A287A9P4 R-SSC-2130282 https://reactome.org/PathwayBrowser/#/R-SSC-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Sus scrofa A0A287A9P4 R-SSC-2130286 https://reactome.org/PathwayBrowser/#/R-SSC-2130286 Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) IEA Sus scrofa A0A287A9P4 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287A9P4 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287A9P4 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287A9P4 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287A9P4 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A287A9P4 R-SSC-388808 https://reactome.org/PathwayBrowser/#/R-SSC-388808 CD28 homodimer binds B7-2 monomer IEA Sus scrofa A0A287A9P4 R-SSC-388809 https://reactome.org/PathwayBrowser/#/R-SSC-388809 CTLA-4 binds B7-1/B7-2 IEA Sus scrofa A0A287A9P4 R-SSC-388811 https://reactome.org/PathwayBrowser/#/R-SSC-388811 CD28 homodimer binds B7-1 homodimer IEA Sus scrofa A0A287A9P4 R-SSC-388833 https://reactome.org/PathwayBrowser/#/R-SSC-388833 Phosphorylation of CTLA-4 IEA Sus scrofa A0A287A9P4 R-SSC-389532 https://reactome.org/PathwayBrowser/#/R-SSC-389532 PP2A binds CTLA4 dimer IEA Sus scrofa A0A287A9P4 R-SSC-432143 https://reactome.org/PathwayBrowser/#/R-SSC-432143 PECAM-1 binds PP2A IEA Sus scrofa A0A287A9P4 R-SSC-5229343 https://reactome.org/PathwayBrowser/#/R-SSC-5229343 AXIN is phosphorylated in the destruction complex IEA Sus scrofa A0A287A9P4 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A287A9P4 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A287A9P4 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A287A9P4 R-SSC-5672957 https://reactome.org/PathwayBrowser/#/R-SSC-5672957 PP2A dephosphorylates KSR1 IEA Sus scrofa A0A287A9P4 R-SSC-5672961 https://reactome.org/PathwayBrowser/#/R-SSC-5672961 PP2A dephosphorylates inactive RAFs IEA Sus scrofa A0A287A9P4 R-SSC-5675431 https://reactome.org/PathwayBrowser/#/R-SSC-5675431 PP2A dephosphorylates RAF1 IEA Sus scrofa A0A287A9P4 R-SSC-6792863 https://reactome.org/PathwayBrowser/#/R-SSC-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Sus scrofa A0A287A9P4 R-SSC-6792871 https://reactome.org/PathwayBrowser/#/R-SSC-6792871 CCNG1 recruits PP2A-PPP2R5C to MDM2 IEA Sus scrofa A0A287A9P4 R-SSC-6811454 https://reactome.org/PathwayBrowser/#/R-SSC-6811454 MAPKs phosphorylate PP2A IEA Sus scrofa A0A287A9P4 R-SSC-6811472 https://reactome.org/PathwayBrowser/#/R-SSC-6811472 IER3 recruits MAPKs to PP2A-B56-beta,gamma IEA Sus scrofa A0A287A9P4 R-SSC-8857925 https://reactome.org/PathwayBrowser/#/R-SSC-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Sus scrofa A0A287A9P4 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287A9R2 R-SSC-6794346 https://reactome.org/PathwayBrowser/#/R-SSC-6794346 NRXNs bind NLGNs IEA Sus scrofa A0A287A9R2 R-SSC-6797554 https://reactome.org/PathwayBrowser/#/R-SSC-6797554 ABP1 binds SHANK proteins IEA Sus scrofa A0A287A9R2 R-SSC-6797568 https://reactome.org/PathwayBrowser/#/R-SSC-6797568 NRXNs bind CASK:Protein 4.1 IEA Sus scrofa A0A287A9R8 R-SSC-5358513 https://reactome.org/PathwayBrowser/#/R-SSC-5358513 MSH2:MSH3 binds insertion/deletion loop of 2 bases or more IEA Sus scrofa A0A287A9R8 R-SSC-5444511 https://reactome.org/PathwayBrowser/#/R-SSC-5444511 Formation of MSH2:MSH3 Complex IEA Sus scrofa A0A287A9R9 R-SSC-5340130 https://reactome.org/PathwayBrowser/#/R-SSC-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Sus scrofa A0A287A9S7 R-SSC-5250930 https://reactome.org/PathwayBrowser/#/R-SSC-5250930 B-WICH recruits histone acetyltransferases IEA Sus scrofa A0A287A9S7 R-SSC-5250938 https://reactome.org/PathwayBrowser/#/R-SSC-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Sus scrofa A0A287A9S7 R-SSC-73757 https://reactome.org/PathwayBrowser/#/R-SSC-73757 Binding of RRN3 to RNA Polymerase I IEA Sus scrofa A0A287A9S7 R-SSC-73758 https://reactome.org/PathwayBrowser/#/R-SSC-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Sus scrofa A0A287A9S7 R-SSC-73769 https://reactome.org/PathwayBrowser/#/R-SSC-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Sus scrofa A0A287A9S7 R-SSC-74986 https://reactome.org/PathwayBrowser/#/R-SSC-74986 Elongation of pre-rRNA transcript IEA Sus scrofa A0A287A9S7 R-SSC-74993 https://reactome.org/PathwayBrowser/#/R-SSC-74993 PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box IEA Sus scrofa A0A287A9U8 R-SSC-111439 https://reactome.org/PathwayBrowser/#/R-SSC-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Sus scrofa A0A287A9U8 R-SSC-158441 https://reactome.org/PathwayBrowser/#/R-SSC-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Sus scrofa A0A287A9U8 R-SSC-158447 https://reactome.org/PathwayBrowser/#/R-SSC-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Sus scrofa A0A287A9U8 R-SSC-158481 https://reactome.org/PathwayBrowser/#/R-SSC-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Sus scrofa A0A287A9U8 R-SSC-158484 https://reactome.org/PathwayBrowser/#/R-SSC-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Sus scrofa A0A287A9U8 R-SSC-159046 https://reactome.org/PathwayBrowser/#/R-SSC-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Sus scrofa A0A287A9U8 R-SSC-159050 https://reactome.org/PathwayBrowser/#/R-SSC-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Sus scrofa A0A287A9U8 R-SSC-191830 https://reactome.org/PathwayBrowser/#/R-SSC-191830 snRNP nuclear import and release IEA Sus scrofa A0A287A9U8 R-SSC-2990880 https://reactome.org/PathwayBrowser/#/R-SSC-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Sus scrofa A0A287A9U8 R-SSC-2990882 https://reactome.org/PathwayBrowser/#/R-SSC-2990882 CDK1 phosphorylates NUP98 IEA Sus scrofa A0A287A9U8 R-SSC-3000348 https://reactome.org/PathwayBrowser/#/R-SSC-3000348 RANBP2 SUMOylates SP100 with SUMO2 IEA Sus scrofa A0A287A9U8 R-SSC-3000399 https://reactome.org/PathwayBrowser/#/R-SSC-3000399 RANBP2 SUMOylates SP100 with SUMO1 IEA Sus scrofa A0A287A9U8 R-SSC-3000411 https://reactome.org/PathwayBrowser/#/R-SSC-3000411 RANBP2 SUMOylates PML with SUMO2 IEA Sus scrofa A0A287A9U8 R-SSC-4551649 https://reactome.org/PathwayBrowser/#/R-SSC-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Sus scrofa A0A287A9U8 R-SSC-4551679 https://reactome.org/PathwayBrowser/#/R-SSC-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Sus scrofa A0A287A9U8 R-SSC-4570493 https://reactome.org/PathwayBrowser/#/R-SSC-4570493 RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 IEA Sus scrofa A0A287A9U8 R-SSC-4615872 https://reactome.org/PathwayBrowser/#/R-SSC-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Sus scrofa A0A287A9U8 R-SSC-4615987 https://reactome.org/PathwayBrowser/#/R-SSC-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Sus scrofa A0A287A9U8 R-SSC-4655355 https://reactome.org/PathwayBrowser/#/R-SSC-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Sus scrofa A0A287A9U8 R-SSC-5228508 https://reactome.org/PathwayBrowser/#/R-SSC-5228508 RANBP2 SUMOylates PML with SUMO1 IEA Sus scrofa A0A287A9U8 R-SSC-5228523 https://reactome.org/PathwayBrowser/#/R-SSC-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Sus scrofa A0A287A9U8 R-SSC-5252041 https://reactome.org/PathwayBrowser/#/R-SSC-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Sus scrofa A0A287A9U8 R-SSC-5578744 https://reactome.org/PathwayBrowser/#/R-SSC-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Sus scrofa A0A287A9U8 R-SSC-75097 https://reactome.org/PathwayBrowser/#/R-SSC-75097 Transport of the export-competent mRNP complex through the NPC IEA Sus scrofa A0A287A9U8 R-SSC-75098 https://reactome.org/PathwayBrowser/#/R-SSC-75098 mRNP complex dissociates from cytosolic face of NPC IEA Sus scrofa A0A287A9U8 R-SSC-77587 https://reactome.org/PathwayBrowser/#/R-SSC-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Sus scrofa A0A287A9U8 R-SSC-77594 https://reactome.org/PathwayBrowser/#/R-SSC-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Sus scrofa A0A287A9U9 R-SSC-2161500 https://reactome.org/PathwayBrowser/#/R-SSC-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Sus scrofa A0A287A9U9 R-SSC-374896 https://reactome.org/PathwayBrowser/#/R-SSC-374896 Uptake of Noradrenaline IEA Sus scrofa A0A287A9U9 R-SSC-374919 https://reactome.org/PathwayBrowser/#/R-SSC-374919 Noradrenaline clearance from the synaptic cleft IEA Sus scrofa A0A287A9U9 R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa A0A287A9U9 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa A0A287A9U9 R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa A0A287A9U9 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa A0A287A9U9 R-SSC-9794523 https://reactome.org/PathwayBrowser/#/R-SSC-9794523 SLC22A1 transports Cipro into renal cell IEA Sus scrofa A0A287A9U9 R-SSC-9795207 https://reactome.org/PathwayBrowser/#/R-SSC-9795207 SLC22A1 transports Cipro into hepatic cell IEA Sus scrofa A0A287A9Y5 R-SSC-198955 https://reactome.org/PathwayBrowser/#/R-SSC-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Sus scrofa A0A287A9Y6 R-SSC-156808 https://reactome.org/PathwayBrowser/#/R-SSC-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Sus scrofa A0A287A9Y6 R-SSC-156823 https://reactome.org/PathwayBrowser/#/R-SSC-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Sus scrofa A0A287A9Y6 R-SSC-157849 https://reactome.org/PathwayBrowser/#/R-SSC-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Sus scrofa A0A287A9Y6 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A287A9Y6 R-SSC-6791221 https://reactome.org/PathwayBrowser/#/R-SSC-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA IEA Sus scrofa A0A287A9Y6 R-SSC-6791222 https://reactome.org/PathwayBrowser/#/R-SSC-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Sus scrofa A0A287A9Y6 R-SSC-6791227 https://reactome.org/PathwayBrowser/#/R-SSC-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Sus scrofa A0A287A9Y6 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa A0A287A9Y6 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A287A9Y6 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A287A9Y6 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A287A9Y6 R-SSC-72676 https://reactome.org/PathwayBrowser/#/R-SSC-72676 eIF3 and eIF1A bind to the 40S subunit IEA Sus scrofa A0A287A9Y6 R-SSC-72691 https://reactome.org/PathwayBrowser/#/R-SSC-72691 Formation of the 43S pre-initiation complex IEA Sus scrofa A0A287A9Y6 R-SSC-72697 https://reactome.org/PathwayBrowser/#/R-SSC-72697 Start codon recognition IEA Sus scrofa A0A287A9Y6 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A287A9Y6 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A287A9Y6 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A287A9Y6 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A287A9Y6 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A287A9Z5 R-SSC-374337 https://reactome.org/PathwayBrowser/#/R-SSC-374337 Apelin receptor binds to apelin IEA Sus scrofa A0A287A9Z5 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287A9Z5 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287A9Z5 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287AA00 R-SSC-4827383 https://reactome.org/PathwayBrowser/#/R-SSC-4827383 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) IEA Sus scrofa A0A287AA00 R-SSC-5638157 https://reactome.org/PathwayBrowser/#/R-SSC-5638157 WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) IEA Sus scrofa A0A287AA01 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A287AA01 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A287AA01 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A287AA01 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A287AA01 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287AA01 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287AA01 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287AA01 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287AA01 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287AA01 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287AA01 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A287AA01 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A287AA01 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A287AA01 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A287AA01 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287AA07 R-SSC-5623524 https://reactome.org/PathwayBrowser/#/R-SSC-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Sus scrofa A0A287AA07 R-SSC-5623527 https://reactome.org/PathwayBrowser/#/R-SSC-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Sus scrofa A0A287AA08 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A287AA08 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A287AA12 R-SSC-210426 https://reactome.org/PathwayBrowser/#/R-SSC-210426 Glutamate synaptic vesicle docking and priming IEA Sus scrofa A0A287AA12 R-SSC-210430 https://reactome.org/PathwayBrowser/#/R-SSC-210430 Release of L-Glutamate at the synapse IEA Sus scrofa A0A287AA12 R-SSC-372505 https://reactome.org/PathwayBrowser/#/R-SSC-372505 Acetylcholine synaptic vesicle docking and priming IEA Sus scrofa A0A287AA12 R-SSC-372529 https://reactome.org/PathwayBrowser/#/R-SSC-372529 Release of acetylcholine at the synapse IEA Sus scrofa A0A287AA12 R-SSC-374899 https://reactome.org/PathwayBrowser/#/R-SSC-374899 Release of noradrenaline at the synapse IEA Sus scrofa A0A287AA12 R-SSC-374922 https://reactome.org/PathwayBrowser/#/R-SSC-374922 Noradrenalin synaptic vesicle docking and priming IEA Sus scrofa A0A287AA12 R-SSC-380574 https://reactome.org/PathwayBrowser/#/R-SSC-380574 Dopamine synaptic vesicle docking and priming IEA Sus scrofa A0A287AA12 R-SSC-380869 https://reactome.org/PathwayBrowser/#/R-SSC-380869 Release of docked dopamine loaded synaptic vesicle IEA Sus scrofa A0A287AA12 R-SSC-380901 https://reactome.org/PathwayBrowser/#/R-SSC-380901 Release of docked serotonin loaded synaptic vesicle IEA Sus scrofa A0A287AA12 R-SSC-380905 https://reactome.org/PathwayBrowser/#/R-SSC-380905 Serotonin loaded synaptic vesicle docking and priming IEA Sus scrofa A0A287AA12 R-SSC-388824 https://reactome.org/PathwayBrowser/#/R-SSC-388824 PTPRF, PTPRS, PTPRD bind Liprins IEA Sus scrofa A0A287AA20 R-SSC-9913330 https://reactome.org/PathwayBrowser/#/R-SSC-9913330 SGCG,SGCZ and SGCA, SGCE bind SGCB:SGCD IEA Sus scrofa A0A287AA20 R-SSC-9913332 https://reactome.org/PathwayBrowser/#/R-SSC-9913332 DAG1(30-653), DAG1(654-895) and SSPN bind SGC IEA Sus scrofa A0A287AA20 R-SSC-9913333 https://reactome.org/PathwayBrowser/#/R-SSC-9913333 DGC complex binds laminins IEA Sus scrofa A0A287AA20 R-SSC-9913336 https://reactome.org/PathwayBrowser/#/R-SSC-9913336 SGC:DAG1:SSPN complex translocates to plasma membrane IEA Sus scrofa A0A287AA20 R-SSC-9913338 https://reactome.org/PathwayBrowser/#/R-SSC-9913338 Sarcoglycan complex (SGC) translocates to the Golgi membrane IEA Sus scrofa A0A287AA20 R-SSC-9913339 https://reactome.org/PathwayBrowser/#/R-SSC-9913339 Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC IEA Sus scrofa A0A287AA20 R-SSC-9914537 https://reactome.org/PathwayBrowser/#/R-SSC-9914537 DGC complex binds AGRN and HSPG2 IEA Sus scrofa A0A287AA21 R-SSC-70870 https://reactome.org/PathwayBrowser/#/R-SSC-70870 ECHS1 hydrates methacrylyl-CoA IEA Sus scrofa A0A287AA21 R-SSC-77256 https://reactome.org/PathwayBrowser/#/R-SSC-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Sus scrofa A0A287AA21 R-SSC-77314 https://reactome.org/PathwayBrowser/#/R-SSC-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Sus scrofa A0A287AA21 R-SSC-77325 https://reactome.org/PathwayBrowser/#/R-SSC-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Sus scrofa A0A287AA21 R-SSC-77333 https://reactome.org/PathwayBrowser/#/R-SSC-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Sus scrofa A0A287AA21 R-SSC-77344 https://reactome.org/PathwayBrowser/#/R-SSC-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Sus scrofa A0A287AA31 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa A0A287AA31 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287AA31 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287AA31 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287AA31 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa A0A287AA42 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287AA42 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287AA42 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287AA42 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287AA42 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287AA42 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287AA42 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287AA42 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287AA42 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287AA42 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AA42 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287AA42 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287AA42 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287AA42 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287AA42 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287AA42 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287AA42 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287AA42 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287AA42 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287AA42 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287AA42 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287AA42 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287AA42 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287AA42 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287AA42 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287AA42 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287AA42 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287AA42 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287AA42 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287AA42 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287AA42 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287AA42 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287AA42 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287AA42 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287AA42 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287AA42 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287AA42 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287AA42 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287AA42 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287AA42 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287AA42 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287AA42 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287AA42 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287AA42 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287AA42 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287AA42 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287AA42 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287AA47 R-SSC-174367 https://reactome.org/PathwayBrowser/#/R-SSC-174367 GCL ligates L-Glu to L-Cys IEA Sus scrofa A0A287AA52 R-SSC-174425 https://reactome.org/PathwayBrowser/#/R-SSC-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Sus scrofa A0A287AA52 R-SSC-174427 https://reactome.org/PathwayBrowser/#/R-SSC-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Sus scrofa A0A287AA52 R-SSC-174452 https://reactome.org/PathwayBrowser/#/R-SSC-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Sus scrofa A0A287AA52 R-SSC-9668597 https://reactome.org/PathwayBrowser/#/R-SSC-9668597 DNA polymerase:primase binds G-strand of the telomere IEA Sus scrofa A0A287AA52 R-SSC-9668831 https://reactome.org/PathwayBrowser/#/R-SSC-9668831 CST complex formation IEA Sus scrofa A0A287AA55 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A287AA56 R-SSC-5223313 https://reactome.org/PathwayBrowser/#/R-SSC-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Sus scrofa A0A287AA56 R-SSC-9759206 https://reactome.org/PathwayBrowser/#/R-SSC-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Sus scrofa A0A287AA58 R-SSC-9629869 https://reactome.org/PathwayBrowser/#/R-SSC-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Sus scrofa A0A287AA58 R-SSC-9629888 https://reactome.org/PathwayBrowser/#/R-SSC-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Sus scrofa A0A287AA61 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A287AA61 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A287AA61 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A287AA61 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A287AA61 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A287AA61 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A287AA61 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A287AA61 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A287AA61 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A287AA61 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287AA61 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A287AA61 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A287AA61 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287AA61 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A287AA61 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287AA61 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287AA61 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287AA61 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287AA61 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287AA61 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A287AA61 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A287AA77 R-SSC-1861595 https://reactome.org/PathwayBrowser/#/R-SSC-1861595 Extension of pseudopodia by myosin-X in a PI3K dependent manner IEA Sus scrofa A0A287AA77 R-SSC-190519 https://reactome.org/PathwayBrowser/#/R-SSC-190519 Internalization of gap junction plaques IEA Sus scrofa A0A287AA77 R-SSC-190829 https://reactome.org/PathwayBrowser/#/R-SSC-190829 Lysosomal degradation of gap junction plaques IEA Sus scrofa A0A287AA77 R-SSC-196017 https://reactome.org/PathwayBrowser/#/R-SSC-196017 Dynamin is recruited to the gap junction plaque IEA Sus scrofa A0A287AA77 R-SSC-196026 https://reactome.org/PathwayBrowser/#/R-SSC-196026 Dab2 is recruited to the junctional plaques IEA Sus scrofa A0A287AA77 R-SSC-2029466 https://reactome.org/PathwayBrowser/#/R-SSC-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Sus scrofa A0A287AA77 R-SSC-2029473 https://reactome.org/PathwayBrowser/#/R-SSC-2029473 Branching and elongation of mother and daughter filaments IEA Sus scrofa A0A287AA77 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287AA77 R-SSC-203070 https://reactome.org/PathwayBrowser/#/R-SSC-203070 Association of profilin with monomeric actin IEA Sus scrofa A0A287AA77 R-SSC-2197690 https://reactome.org/PathwayBrowser/#/R-SSC-2197690 Detachment of WASP/WAVE IEA Sus scrofa A0A287AA77 R-SSC-3928595 https://reactome.org/PathwayBrowser/#/R-SSC-3928595 N-WASP binds ARP2/3 and G-actin IEA Sus scrofa A0A287AA77 R-SSC-430347 https://reactome.org/PathwayBrowser/#/R-SSC-430347 MigFilin associates with Filamin and F-actin IEA Sus scrofa A0A287AA77 R-SSC-482772 https://reactome.org/PathwayBrowser/#/R-SSC-482772 Release of platelet cytosolic components IEA Sus scrofa A0A287AA77 R-SSC-5218916 https://reactome.org/PathwayBrowser/#/R-SSC-5218916 p-MAPK2/3 phosphorylates HSP27 IEA Sus scrofa A0A287AA77 R-SSC-5626507 https://reactome.org/PathwayBrowser/#/R-SSC-5626507 IQGAPs bind F-actin, which is inhibited by calmodulin IEA Sus scrofa A0A287AA77 R-SSC-5665751 https://reactome.org/PathwayBrowser/#/R-SSC-5665751 CDC42:GTP:FMNL2 binds Profilin:G-actin IEA Sus scrofa A0A287AA77 R-SSC-5665767 https://reactome.org/PathwayBrowser/#/R-SSC-5665767 Activated FMNL3 binds G-actin IEA Sus scrofa A0A287AA77 R-SSC-5665802 https://reactome.org/PathwayBrowser/#/R-SSC-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Sus scrofa A0A287AA77 R-SSC-5665809 https://reactome.org/PathwayBrowser/#/R-SSC-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Sus scrofa A0A287AA77 R-SSC-5665982 https://reactome.org/PathwayBrowser/#/R-SSC-5665982 RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 IEA Sus scrofa A0A287AA77 R-SSC-5666001 https://reactome.org/PathwayBrowser/#/R-SSC-5666001 Profilin:G-actin binds MKL1 IEA Sus scrofa A0A287AA77 R-SSC-5672972 https://reactome.org/PathwayBrowser/#/R-SSC-5672972 MAP2Ks and MAPKs bind to the activated RAF complex IEA Sus scrofa A0A287AA77 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa A0A287AA77 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa A0A287AA77 R-SSC-5672980 https://reactome.org/PathwayBrowser/#/R-SSC-5672980 Dissociation of RAS:RAF complex IEA Sus scrofa A0A287AA77 R-SSC-5692437 https://reactome.org/PathwayBrowser/#/R-SSC-5692437 ANG binds F-actin IEA Sus scrofa A0A287AA77 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A287AA77 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287AA77 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287AA77 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287AA77 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287AA77 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287AA77 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287AA77 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287AA77 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287AA77 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287AA77 R-SSC-9018787 https://reactome.org/PathwayBrowser/#/R-SSC-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Sus scrofa A0A287AA77 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa A0A287AA77 R-SSC-9657603 https://reactome.org/PathwayBrowser/#/R-SSC-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Sus scrofa A0A287AA77 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa A0A287AA77 R-SSC-9657608 https://reactome.org/PathwayBrowser/#/R-SSC-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Sus scrofa A0A287AA77 R-SSC-9693125 https://reactome.org/PathwayBrowser/#/R-SSC-9693125 RHOF binds effectors at the plasma membrane IEA Sus scrofa A0A287AA77 R-SSC-9914537 https://reactome.org/PathwayBrowser/#/R-SSC-9914537 DGC complex binds AGRN and HSPG2 IEA Sus scrofa A0A287AA82 R-SSC-2025890 https://reactome.org/PathwayBrowser/#/R-SSC-2025890 Calcineurin binds NFATC1,2,3 IEA Sus scrofa A0A287AA82 R-SSC-2730849 https://reactome.org/PathwayBrowser/#/R-SSC-2730849 Calcineurin binds and dephosphorylates NFAT IEA Sus scrofa A0A287AA82 R-SSC-2730867 https://reactome.org/PathwayBrowser/#/R-SSC-2730867 Translocation of CaN:CaM:NFAT to nucleus IEA Sus scrofa A0A287AA82 R-SSC-4551451 https://reactome.org/PathwayBrowser/#/R-SSC-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Sus scrofa A0A287AA82 R-SSC-4551465 https://reactome.org/PathwayBrowser/#/R-SSC-4551465 Translocation of NFATC1:CaN:CaM to nucleus IEA Sus scrofa A0A287AA85 R-SSC-3296309 https://reactome.org/PathwayBrowser/#/R-SSC-3296309 HCAR3 binds HCAR3 ligands IEA Sus scrofa A0A287AA85 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287AA85 R-SSC-444661 https://reactome.org/PathwayBrowser/#/R-SSC-444661 HCAR2 binds HCAR2 ligands IEA Sus scrofa A0A287AA85 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287AA85 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287AA98 R-SSC-376419 https://reactome.org/PathwayBrowser/#/R-SSC-376419 Formation of NR-MED1 Coactivator Complex IEA Sus scrofa A0A287AA98 R-SSC-382096 https://reactome.org/PathwayBrowser/#/R-SSC-382096 Formation of NR-NCOR Corepressor Complex IEA Sus scrofa A0A287AAC2 R-SSC-8940388 https://reactome.org/PathwayBrowser/#/R-SSC-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Sus scrofa A0A287AAC7 R-SSC-212356 https://reactome.org/PathwayBrowser/#/R-SSC-212356 Formation of CSL-NICD coactivator complex IEA Sus scrofa A0A287AAC7 R-SSC-8878220 https://reactome.org/PathwayBrowser/#/R-SSC-8878220 RUNX3 binds the NOTCH1 coactivator complex IEA Sus scrofa A0A287AAE4 R-SSC-109699 https://reactome.org/PathwayBrowser/#/R-SSC-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Sus scrofa A0A287AAE4 R-SSC-190256 https://reactome.org/PathwayBrowser/#/R-SSC-190256 FGFR1c binds to FGF IEA Sus scrofa A0A287AAE4 R-SSC-190429 https://reactome.org/PathwayBrowser/#/R-SSC-190429 Autocatalytic phosphorylation of FGFR1c IEA Sus scrofa A0A287AAE4 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AAE4 R-SSC-5654149 https://reactome.org/PathwayBrowser/#/R-SSC-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Sus scrofa A0A287AAE4 R-SSC-5654165 https://reactome.org/PathwayBrowser/#/R-SSC-5654165 p-4Y-PLCG1 dissociates from activated FGFR1 IEA Sus scrofa A0A287AAE4 R-SSC-5654167 https://reactome.org/PathwayBrowser/#/R-SSC-5654167 Activated FGFR1 binds PLCG1 IEA Sus scrofa A0A287AAE4 R-SSC-5654392 https://reactome.org/PathwayBrowser/#/R-SSC-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A287AAE4 R-SSC-5654511 https://reactome.org/PathwayBrowser/#/R-SSC-5654511 FGFRL1 dimer binds FGFs IEA Sus scrofa A0A287AAE4 R-SSC-5654560 https://reactome.org/PathwayBrowser/#/R-SSC-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2 IEA Sus scrofa A0A287AAE4 R-SSC-5654569 https://reactome.org/PathwayBrowser/#/R-SSC-5654569 Activated FGFR1 binds FRS2 IEA Sus scrofa A0A287AAE4 R-SSC-5654571 https://reactome.org/PathwayBrowser/#/R-SSC-5654571 Activated FGFR1 binds FRS3 IEA Sus scrofa A0A287AAE4 R-SSC-5654573 https://reactome.org/PathwayBrowser/#/R-SSC-5654573 Activated FGFR1 binds SHC1 IEA Sus scrofa A0A287AAE4 R-SSC-5654575 https://reactome.org/PathwayBrowser/#/R-SSC-5654575 Activated FGFR1 phosphorylates FRS2 IEA Sus scrofa A0A287AAE4 R-SSC-5654578 https://reactome.org/PathwayBrowser/#/R-SSC-5654578 Activated FGFR1 phosphorylates FRS3 IEA Sus scrofa A0A287AAE4 R-SSC-5654582 https://reactome.org/PathwayBrowser/#/R-SSC-5654582 Activated FGFR1 phosphorylates SHC1 IEA Sus scrofa A0A287AAE4 R-SSC-5654584 https://reactome.org/PathwayBrowser/#/R-SSC-5654584 Activated FGFR1:p-FRS bind to PPTN11 IEA Sus scrofa A0A287AAE4 R-SSC-5654586 https://reactome.org/PathwayBrowser/#/R-SSC-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Sus scrofa A0A287AAE4 R-SSC-5654587 https://reactome.org/PathwayBrowser/#/R-SSC-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Sus scrofa A0A287AAE4 R-SSC-5654591 https://reactome.org/PathwayBrowser/#/R-SSC-5654591 Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Sus scrofa A0A287AAE4 R-SSC-5654592 https://reactome.org/PathwayBrowser/#/R-SSC-5654592 Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Sus scrofa A0A287AAE4 R-SSC-5654594 https://reactome.org/PathwayBrowser/#/R-SSC-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Sus scrofa A0A287AAE4 R-SSC-5654596 https://reactome.org/PathwayBrowser/#/R-SSC-5654596 Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Sus scrofa A0A287AAE4 R-SSC-5654597 https://reactome.org/PathwayBrowser/#/R-SSC-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Sus scrofa A0A287AAE4 R-SSC-5654600 https://reactome.org/PathwayBrowser/#/R-SSC-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A287AAE4 R-SSC-5654672 https://reactome.org/PathwayBrowser/#/R-SSC-5654672 CBL ubiquitinates FRS2 and FGFR1 IEA Sus scrofa A0A287AAE4 R-SSC-5654673 https://reactome.org/PathwayBrowser/#/R-SSC-5654673 p-CBL:GRB2 binds p-FRS2:activated FGFR1 IEA Sus scrofa A0A287AAE4 R-SSC-5654690 https://reactome.org/PathwayBrowser/#/R-SSC-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AAE4 R-SSC-5654692 https://reactome.org/PathwayBrowser/#/R-SSC-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AAE4 R-SSC-5656064 https://reactome.org/PathwayBrowser/#/R-SSC-5656064 Activated FGFR1 binds FLRT1,2,3 IEA Sus scrofa A0A287AAE4 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287AAE4 R-SSC-8941623 https://reactome.org/PathwayBrowser/#/R-SSC-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Sus scrofa A0A287AAE8 R-SSC-8847880 https://reactome.org/PathwayBrowser/#/R-SSC-8847880 CYTH proteins bind ARF1:GTP IEA Sus scrofa A0A287AAE8 R-SSC-8847883 https://reactome.org/PathwayBrowser/#/R-SSC-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Sus scrofa A0A287AAG7 R-SSC-204169 https://reactome.org/PathwayBrowser/#/R-SSC-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Sus scrofa A0A287AAG8 R-SSC-202704 https://reactome.org/PathwayBrowser/#/R-SSC-202704 Integrin alphaXbeta2 binds JAM3 IEA Sus scrofa A0A287AAG8 R-SSC-216082 https://reactome.org/PathwayBrowser/#/R-SSC-216082 Interaction of integrin alphaXbeta2 with fibrin IEA Sus scrofa A0A287AAG8 R-SSC-2681667 https://reactome.org/PathwayBrowser/#/R-SSC-2681667 TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 IEA Sus scrofa A0A287AAG8 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A287AAG8 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A287AAG8 R-SSC-6800426 https://reactome.org/PathwayBrowser/#/R-SSC-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Sus scrofa A0A287AAH2 R-SSC-204500 https://reactome.org/PathwayBrowser/#/R-SSC-204500 CyP60 chaperones Basigin IEA Sus scrofa A0A287AAH2 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A287AAH2 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287AAH2 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A287AAH2 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A287AAJ2 R-SSC-2744242 https://reactome.org/PathwayBrowser/#/R-SSC-2744242 TTYH2/3 transport cytosolic Cl- to extracellular region IEA Sus scrofa A0A287AAJ4 R-SSC-1504186 https://reactome.org/PathwayBrowser/#/R-SSC-1504186 DVL recruits GSK3beta:AXIN1 to the receptor complex IEA Sus scrofa A0A287AAJ4 R-SSC-201677 https://reactome.org/PathwayBrowser/#/R-SSC-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Sus scrofa A0A287AAJ4 R-SSC-201685 https://reactome.org/PathwayBrowser/#/R-SSC-201685 Beta-catenin is released from the destruction complex IEA Sus scrofa A0A287AAJ4 R-SSC-3769397 https://reactome.org/PathwayBrowser/#/R-SSC-3769397 SOST binds LRP5/6 IEA Sus scrofa A0A287AAJ4 R-SSC-3769401 https://reactome.org/PathwayBrowser/#/R-SSC-3769401 DKK and KRM bind LRP5/6 IEA Sus scrofa A0A287AAJ4 R-SSC-4641236 https://reactome.org/PathwayBrowser/#/R-SSC-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Sus scrofa A0A287AAJ4 R-SSC-4641249 https://reactome.org/PathwayBrowser/#/R-SSC-4641249 ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex IEA Sus scrofa A0A287AAJ4 R-SSC-4641253 https://reactome.org/PathwayBrowser/#/R-SSC-4641253 ZNRF3 ubiquitinates FZD to promote its downregulation IEA Sus scrofa A0A287AAJ4 R-SSC-5368586 https://reactome.org/PathwayBrowser/#/R-SSC-5368586 DKK promotes clathrin-dependent internalization of LRP6 IEA Sus scrofa A0A287AAJ4 R-SSC-5368596 https://reactome.org/PathwayBrowser/#/R-SSC-5368596 WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 IEA Sus scrofa A0A287AAK1 R-SSC-6781833 https://reactome.org/PathwayBrowser/#/R-SSC-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Sus scrofa A0A287AAK1 R-SSC-8863721 https://reactome.org/PathwayBrowser/#/R-SSC-8863721 NEDD8-STON binds TOR1 hexamer and COP9 complex IEA Sus scrofa A0A287AAK1 R-SSC-8863723 https://reactome.org/PathwayBrowser/#/R-SSC-8863723 COP9 and TOR1 deneddylate STON2 IEA Sus scrofa A0A287AAK1 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AAK1 R-SSC-8956045 https://reactome.org/PathwayBrowser/#/R-SSC-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AAK1 R-SSC-9018778 https://reactome.org/PathwayBrowser/#/R-SSC-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Sus scrofa A0A287AAK5 R-SSC-1483203 https://reactome.org/PathwayBrowser/#/R-SSC-1483203 PA is dephosphorylated to DAG by LPIN IEA Sus scrofa A0A287AAK5 R-SSC-4419948 https://reactome.org/PathwayBrowser/#/R-SSC-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Sus scrofa A0A287AAK5 R-SSC-5195402 https://reactome.org/PathwayBrowser/#/R-SSC-5195402 CDK1 phosphorylates LPIN IEA Sus scrofa A0A287AAK5 R-SSC-5221130 https://reactome.org/PathwayBrowser/#/R-SSC-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Sus scrofa A0A287AAK5 R-SSC-75899 https://reactome.org/PathwayBrowser/#/R-SSC-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Sus scrofa A0A287AAM5 R-SSC-8981637 https://reactome.org/PathwayBrowser/#/R-SSC-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Sus scrofa A0A287AAM5 R-SSC-9013022 https://reactome.org/PathwayBrowser/#/R-SSC-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Sus scrofa A0A287AAM5 R-SSC-9013161 https://reactome.org/PathwayBrowser/#/R-SSC-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Sus scrofa A0A287AAM6 R-SSC-917696 https://reactome.org/PathwayBrowser/#/R-SSC-917696 Cargo Sequestration IEA Sus scrofa A0A287AAM6 R-SSC-917700 https://reactome.org/PathwayBrowser/#/R-SSC-917700 MVB Vesicle Formation IEA Sus scrofa A0A287AAP2 R-SSC-5676637 https://reactome.org/PathwayBrowser/#/R-SSC-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Sus scrofa A0A287AAP7 R-SSC-1549526 https://reactome.org/PathwayBrowser/#/R-SSC-1549526 Phosphorylation of SMAD2,3 by Activin:Activin Receptor IEA Sus scrofa A0A287AAQ1 R-SSC-917696 https://reactome.org/PathwayBrowser/#/R-SSC-917696 Cargo Sequestration IEA Sus scrofa A0A287AAQ1 R-SSC-917730 https://reactome.org/PathwayBrowser/#/R-SSC-917730 Cargo Recognition And Sorting IEA Sus scrofa A0A287AAR5 R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Sus scrofa A0A287AAR5 R-SSC-6793590 https://reactome.org/PathwayBrowser/#/R-SSC-6793590 LIPT2 transfers octanoyl group to GCSH IEA Sus scrofa A0A287AAR5 R-SSC-6799179 https://reactome.org/PathwayBrowser/#/R-SSC-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Sus scrofa A0A287AAR5 R-SSC-6799191 https://reactome.org/PathwayBrowser/#/R-SSC-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Sus scrofa A0A287AAR5 R-SSC-6799196 https://reactome.org/PathwayBrowser/#/R-SSC-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Sus scrofa A0A287AAR5 R-SSC-6799202 https://reactome.org/PathwayBrowser/#/R-SSC-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Sus scrofa A0A287AAR5 R-SSC-8933547 https://reactome.org/PathwayBrowser/#/R-SSC-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 IEA Sus scrofa A0A287AAT1 R-SSC-5671993 https://reactome.org/PathwayBrowser/#/R-SSC-5671993 CIT-3 binds DLG4 IEA Sus scrofa A0A287AAT1 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa A0A287AAT1 R-SSC-9013024 https://reactome.org/PathwayBrowser/#/R-SSC-9013024 RHOB binds effectors at the plasma membrane IEA Sus scrofa A0A287AAT1 R-SSC-9013110 https://reactome.org/PathwayBrowser/#/R-SSC-9013110 RHOC binds effectors at the plasma membrane IEA Sus scrofa A0A287AAT1 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A287AAX2 R-SSC-8870332 https://reactome.org/PathwayBrowser/#/R-SSC-8870332 PTPN13:PLEKHA1,2 bind PI(3,4)P2 IEA Sus scrofa A0A287AB08 R-SSC-8931653 https://reactome.org/PathwayBrowser/#/R-SSC-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 IEA Sus scrofa A0A287AB27 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AB27 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287AB27 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AB27 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AB29 R-SSC-9933559 https://reactome.org/PathwayBrowser/#/R-SSC-9933559 The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1 IEA Sus scrofa A0A287AB29 R-SSC-9933575 https://reactome.org/PathwayBrowser/#/R-SSC-9933575 MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome IEA Sus scrofa A0A287AB29 R-SSC-9933585 https://reactome.org/PathwayBrowser/#/R-SSC-9933585 RNA exosome in PAXT:PAPOLG:TENT4A,B:ZC3H3:CBCA:polyadenylated m7GpppN-RNA:PABPN1 hydrolyzes RNA IEA Sus scrofa A0A287AB45 R-SSC-70467 https://reactome.org/PathwayBrowser/#/R-SSC-70467 PFK tetramer phosphorylates Fru(6)P IEA Sus scrofa A0A287AB49 R-SSC-191414 https://reactome.org/PathwayBrowser/#/R-SSC-191414 MVD decarboxylates MVA5PP to IPPP IEA Sus scrofa A0A287AB58 R-SSC-1169394 https://reactome.org/PathwayBrowser/#/R-SSC-1169394 ISGylation of IRF3 IEA Sus scrofa A0A287AB58 R-SSC-1169397 https://reactome.org/PathwayBrowser/#/R-SSC-1169397 Activation of ISG15 by UBA7 E1 ligase IEA Sus scrofa A0A287AB58 R-SSC-1169398 https://reactome.org/PathwayBrowser/#/R-SSC-1169398 ISGylation of host protein filamin B IEA Sus scrofa A0A287AB58 R-SSC-1169399 https://reactome.org/PathwayBrowser/#/R-SSC-1169399 Interaction of ISG15 with NEDD4 and inhibition of Ebola virus budding IEA Sus scrofa A0A287AB58 R-SSC-1169402 https://reactome.org/PathwayBrowser/#/R-SSC-1169402 ISGylation of E2 conjugating enzymes IEA Sus scrofa A0A287AB58 R-SSC-1169403 https://reactome.org/PathwayBrowser/#/R-SSC-1169403 Interaction of E3 ligase with ISG15:E2 complex IEA Sus scrofa A0A287AB58 R-SSC-1169404 https://reactome.org/PathwayBrowser/#/R-SSC-1169404 Transfer of ISG15 from E1 to E2 (UBCH8) IEA Sus scrofa A0A287AB58 R-SSC-1169405 https://reactome.org/PathwayBrowser/#/R-SSC-1169405 ISGylation of protein phosphatase 1 beta (PP2CB) IEA Sus scrofa A0A287AB58 R-SSC-1169406 https://reactome.org/PathwayBrowser/#/R-SSC-1169406 ISGylation of host proteins IEA Sus scrofa A0A287AB58 R-SSC-1678841 https://reactome.org/PathwayBrowser/#/R-SSC-1678841 Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 IEA Sus scrofa A0A287AB58 R-SSC-1678842 https://reactome.org/PathwayBrowser/#/R-SSC-1678842 Competitive inhibition of translation initiation by ISGylated 4EHP IEA Sus scrofa A0A287AB58 R-SSC-1678843 https://reactome.org/PathwayBrowser/#/R-SSC-1678843 ISGylation of protein translation regulator 4EHP IEA Sus scrofa A0A287AB58 R-SSC-5653754 https://reactome.org/PathwayBrowser/#/R-SSC-5653754 UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA IEA Sus scrofa A0A287AB58 R-SSC-5653766 https://reactome.org/PathwayBrowser/#/R-SSC-5653766 USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A287AB58 R-SSC-5653770 https://reactome.org/PathwayBrowser/#/R-SSC-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A287AB58 R-SSC-5653780 https://reactome.org/PathwayBrowser/#/R-SSC-5653780 USP43 binds ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A287AB58 R-SSC-5653786 https://reactome.org/PathwayBrowser/#/R-SSC-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A287AB58 R-SSC-936563 https://reactome.org/PathwayBrowser/#/R-SSC-936563 ISGylation of DDX58 IEA Sus scrofa A0A287AB58 R-SSC-9833973 https://reactome.org/PathwayBrowser/#/R-SSC-9833973 ISGylation of PKR IEA Sus scrofa A0A287AB58 R-SSC-9927247 https://reactome.org/PathwayBrowser/#/R-SSC-9927247 ISGylation of DDX58 (RIG-I) IEA Sus scrofa A0A287AB60 R-SSC-4724279 https://reactome.org/PathwayBrowser/#/R-SSC-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Sus scrofa A0A287AB60 R-SSC-5625796 https://reactome.org/PathwayBrowser/#/R-SSC-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Sus scrofa A0A287AB60 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa A0A287AB60 R-SSC-5661120 https://reactome.org/PathwayBrowser/#/R-SSC-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Sus scrofa A0A287AB66 R-SSC-6781833 https://reactome.org/PathwayBrowser/#/R-SSC-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Sus scrofa A0A287AB66 R-SSC-8863721 https://reactome.org/PathwayBrowser/#/R-SSC-8863721 NEDD8-STON binds TOR1 hexamer and COP9 complex IEA Sus scrofa A0A287AB66 R-SSC-8863723 https://reactome.org/PathwayBrowser/#/R-SSC-8863723 COP9 and TOR1 deneddylate STON2 IEA Sus scrofa A0A287AB66 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AB66 R-SSC-8956045 https://reactome.org/PathwayBrowser/#/R-SSC-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AB80 R-SSC-8852129 https://reactome.org/PathwayBrowser/#/R-SSC-8852129 UBA1 conjugates ubiquitin to cytosolic E2 enzymes IEA Sus scrofa A0A287AB80 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AB80 R-SSC-983152 https://reactome.org/PathwayBrowser/#/R-SSC-983152 Transfer of ubiquitin from E1 to E2 IEA Sus scrofa A0A287AB80 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AB80 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AB83 R-SSC-2684901 https://reactome.org/PathwayBrowser/#/R-SSC-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Sus scrofa A0A287AB95 R-SSC-9706293 https://reactome.org/PathwayBrowser/#/R-SSC-9706293 Active FLT3 binds to CBL IEA Sus scrofa A0A287AB95 R-SSC-9706319 https://reactome.org/PathwayBrowser/#/R-SSC-9706319 Active FLT3 binds to SLA IEA Sus scrofa A0A287ABA7 R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa A0A287ABA7 R-SSC-9679787 https://reactome.org/PathwayBrowser/#/R-SSC-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Sus scrofa A0A287ABC1 R-SSC-163625 https://reactome.org/PathwayBrowser/#/R-SSC-163625 Glucagon binds to Glucagon receptor IEA Sus scrofa A0A287ABC1 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa A0A287ABC1 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287ABC1 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287ABC1 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287ABD5 R-SSC-6805546 https://reactome.org/PathwayBrowser/#/R-SSC-6805546 Keratin type I binds keratin type II IEA Sus scrofa A0A287ABD5 R-SSC-6805573 https://reactome.org/PathwayBrowser/#/R-SSC-6805573 Keratin type I/type II heterodimers form tetramers IEA Sus scrofa A0A287ABD5 R-SSC-6806610 https://reactome.org/PathwayBrowser/#/R-SSC-6806610 Keratin filament formation IEA Sus scrofa A0A287ABD5 R-SSC-6806613 https://reactome.org/PathwayBrowser/#/R-SSC-6806613 Keratin tetramers bind to form unit length filaments IEA Sus scrofa A0A287ABD5 R-SSC-6806629 https://reactome.org/PathwayBrowser/#/R-SSC-6806629 Formation of tonofilament bundles IEA Sus scrofa A0A287ABD5 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A287ABD5 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287ABD5 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A287ABD5 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A287ABD7 R-SSC-4570528 https://reactome.org/PathwayBrowser/#/R-SSC-4570528 SUMOylation of XPC with SUMO1 IEA Sus scrofa A0A287ABD7 R-SSC-5689861 https://reactome.org/PathwayBrowser/#/R-SSC-5689861 Recruitment of XPA and release of CAK IEA Sus scrofa A0A287ABD7 R-SSC-5690996 https://reactome.org/PathwayBrowser/#/R-SSC-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Sus scrofa A0A287ABD7 R-SSC-5691000 https://reactome.org/PathwayBrowser/#/R-SSC-5691000 TFIIH binds GG-NER site to form a verification complex IEA Sus scrofa A0A287ABD7 R-SSC-5696655 https://reactome.org/PathwayBrowser/#/R-SSC-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Sus scrofa A0A287ABD7 R-SSC-5696664 https://reactome.org/PathwayBrowser/#/R-SSC-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Sus scrofa A0A287ABD7 R-SSC-5696670 https://reactome.org/PathwayBrowser/#/R-SSC-5696670 CHD1L is recruited to GG-NER site IEA Sus scrofa A0A287ABD7 R-SSC-6782943 https://reactome.org/PathwayBrowser/#/R-SSC-6782943 UV-DDB ubiquitinates XPC IEA Sus scrofa A0A287ABD7 R-SSC-6790454 https://reactome.org/PathwayBrowser/#/R-SSC-6790454 SUMOylation of XPC IEA Sus scrofa A0A287ABF3 R-SSC-5678490 https://reactome.org/PathwayBrowser/#/R-SSC-5678490 ATG16L1 complex transfers LC3 from ATG3 to PE IEA Sus scrofa A0A287ABF3 R-SSC-5681987 https://reactome.org/PathwayBrowser/#/R-SSC-5681987 LC3 is cleaved by ATG4 IEA Sus scrofa A0A287ABF3 R-SSC-5682011 https://reactome.org/PathwayBrowser/#/R-SSC-5682011 LC3 binds ATG7 dimer IEA Sus scrofa A0A287ABF3 R-SSC-5682377 https://reactome.org/PathwayBrowser/#/R-SSC-5682377 LC3 de-lipidation by ATG4 IEA Sus scrofa A0A287ABF3 R-SSC-5682388 https://reactome.org/PathwayBrowser/#/R-SSC-5682388 Autophagosome maturation IEA Sus scrofa A0A287ABF9 R-SSC-374723 https://reactome.org/PathwayBrowser/#/R-SSC-374723 Nociceptin receptor binds to nociceptin IEA Sus scrofa A0A287ABF9 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287ABF9 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287ABF9 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287ABG0 R-SSC-2454081 https://reactome.org/PathwayBrowser/#/R-SSC-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Sus scrofa A0A287ABG0 R-SSC-2454264 https://reactome.org/PathwayBrowser/#/R-SSC-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Sus scrofa A0A287ABG0 R-SSC-2465919 https://reactome.org/PathwayBrowser/#/R-SSC-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Sus scrofa A0A287ABG0 R-SSC-2465971 https://reactome.org/PathwayBrowser/#/R-SSC-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Sus scrofa A0A287ABG0 R-SSC-74872 https://reactome.org/PathwayBrowser/#/R-SSC-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Sus scrofa A0A287ABG0 R-SSC-8960973 https://reactome.org/PathwayBrowser/#/R-SSC-8960973 RLBP1:11cRAL dissociates IEA Sus scrofa A0A287ABH5 R-SSC-8943959 https://reactome.org/PathwayBrowser/#/R-SSC-8943959 MMP2, MMP9 cleave SCUBE3 IEA Sus scrofa A0A287ABH5 R-SSC-8943987 https://reactome.org/PathwayBrowser/#/R-SSC-8943987 SCUBE1, SCUBE3 oligomerize IEA Sus scrofa A0A287ABI0 R-SSC-5632732 https://reactome.org/PathwayBrowser/#/R-SSC-5632732 p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 IEA Sus scrofa A0A287ABI0 R-SSC-5632738 https://reactome.org/PathwayBrowser/#/R-SSC-5632738 DDIT4 binds 14-3-3 dimer IEA Sus scrofa A0A287ABI5 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287ABI5 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287ABI5 R-SSC-419389 https://reactome.org/PathwayBrowser/#/R-SSC-419389 LPA-binding receptors bind LPA IEA Sus scrofa A0A287ABI5 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287ABI5 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287ABI5 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287ABI5 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287ABJ0 R-SSC-5696838 https://reactome.org/PathwayBrowser/#/R-SSC-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Sus scrofa A0A287ABJ2 R-SSC-209845 https://reactome.org/PathwayBrowser/#/R-SSC-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Sus scrofa A0A287ABJ3 R-SSC-9639287 https://reactome.org/PathwayBrowser/#/R-SSC-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Sus scrofa A0A287ABJ3 R-SSC-9640195 https://reactome.org/PathwayBrowser/#/R-SSC-9640195 RRAGA,B hydrolyzes GTP IEA Sus scrofa A0A287ABJ3 R-SSC-9640237 https://reactome.org/PathwayBrowser/#/R-SSC-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Sus scrofa A0A287ABJ3 R-SSC-9640254 https://reactome.org/PathwayBrowser/#/R-SSC-9640254 BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 IEA Sus scrofa A0A287ABJ3 R-SSC-9657619 https://reactome.org/PathwayBrowser/#/R-SSC-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 IEA Sus scrofa A0A287ABK7 R-SSC-1454916 https://reactome.org/PathwayBrowser/#/R-SSC-1454916 The ABCC family mediates organic anion transport IEA Sus scrofa A0A287ABK7 R-SSC-266070 https://reactome.org/PathwayBrowser/#/R-SSC-266070 LTC4 is exported from the cytosol by ABCC1 IEA Sus scrofa A0A287ABK7 R-SSC-3095901 https://reactome.org/PathwayBrowser/#/R-SSC-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Sus scrofa A0A287ABK7 R-SSC-9661405 https://reactome.org/PathwayBrowser/#/R-SSC-9661405 ABCC1 transports BIL from cytosol to extracellular region (blood) IEA Sus scrofa A0A287ABK7 R-SSC-9753284 https://reactome.org/PathwayBrowser/#/R-SSC-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Sus scrofa A0A287ABK7 R-SSC-9843721 https://reactome.org/PathwayBrowser/#/R-SSC-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Sus scrofa A0A287ABL7 R-SSC-425994 https://reactome.org/PathwayBrowser/#/R-SSC-425994 Na+/H+ exchanger transport (at cell membrane) IEA Sus scrofa A0A287ABM6 R-SSC-1222516 https://reactome.org/PathwayBrowser/#/R-SSC-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Sus scrofa A0A287ABM6 R-SSC-5252133 https://reactome.org/PathwayBrowser/#/R-SSC-5252133 ATP6AP1 binds V-ATPase IEA Sus scrofa A0A287ABM6 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A287ABM6 R-SSC-6800426 https://reactome.org/PathwayBrowser/#/R-SSC-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Sus scrofa A0A287ABM6 R-SSC-74723 https://reactome.org/PathwayBrowser/#/R-SSC-74723 Endosome acidification IEA Sus scrofa A0A287ABM6 R-SSC-917841 https://reactome.org/PathwayBrowser/#/R-SSC-917841 Acidification of Tf:TfR1 containing endosome IEA Sus scrofa A0A287ABN3 R-SSC-428696 https://reactome.org/PathwayBrowser/#/R-SSC-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Sus scrofa A0A287ABN4 R-SSC-5690845 https://reactome.org/PathwayBrowser/#/R-SSC-5690845 TNIPs bind TNFAIP3 (A20) IEA Sus scrofa A0A287ABQ3 R-SSC-212222 https://reactome.org/PathwayBrowser/#/R-SSC-212222 PRC2 recruits DNA methyltransferases IEA Sus scrofa A0A287ABQ3 R-SSC-212269 https://reactome.org/PathwayBrowser/#/R-SSC-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Sus scrofa A0A287ABQ3 R-SSC-4655374 https://reactome.org/PathwayBrowser/#/R-SSC-4655374 SUMOylation of DNMT3B with SUMO1 IEA Sus scrofa A0A287ABQ5 R-SSC-166869 https://reactome.org/PathwayBrowser/#/R-SSC-166869 TRAF6 binds MEKK1 IEA Sus scrofa A0A287ABQ5 R-SSC-2730896 https://reactome.org/PathwayBrowser/#/R-SSC-2730896 Phosphorylation of MEK4 by MEKK1 IEA Sus scrofa A0A287ABQ9 R-SSC-549241 https://reactome.org/PathwayBrowser/#/R-SSC-549241 SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol IEA Sus scrofa A0A287ABQ9 R-SSC-549297 https://reactome.org/PathwayBrowser/#/R-SSC-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Sus scrofa A0A287ABR0 R-SSC-1675949 https://reactome.org/PathwayBrowser/#/R-SSC-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Sus scrofa A0A287ABR0 R-SSC-1855218 https://reactome.org/PathwayBrowser/#/R-SSC-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Sus scrofa A0A287ABR0 R-SSC-202237 https://reactome.org/PathwayBrowser/#/R-SSC-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Sus scrofa A0A287ABR0 R-SSC-210290 https://reactome.org/PathwayBrowser/#/R-SSC-210290 Interaction of PECAM-1 and SHIP IEA Sus scrofa A0A287ABR0 R-SSC-913374 https://reactome.org/PathwayBrowser/#/R-SSC-913374 Phosphorylated SHC1 recruits SHIP IEA Sus scrofa A0A287ABR1 R-SSC-9696266 https://reactome.org/PathwayBrowser/#/R-SSC-9696266 RND2 binds effectors IEA Sus scrofa A0A287ABS5 R-SSC-5696947 https://reactome.org/PathwayBrowser/#/R-SSC-5696947 USP47 deubiquitinates POLB IEA Sus scrofa A0A287ABU6 R-SSC-197963 https://reactome.org/PathwayBrowser/#/R-SSC-197963 DHFR2 reduces FOLA to DHF IEA Sus scrofa A0A287ABU6 R-SSC-197972 https://reactome.org/PathwayBrowser/#/R-SSC-197972 DHF is reduced to tetrahydrofolate (THF) IEA Sus scrofa A0A287ABU6 R-SSC-9709098 https://reactome.org/PathwayBrowser/#/R-SSC-9709098 DHFR dimer reduces FOLA to DHF IEA Sus scrofa A0A287ABU6 R-SSC-9709109 https://reactome.org/PathwayBrowser/#/R-SSC-9709109 DHFR dimer binds DHFR inhibitors IEA Sus scrofa A0A287ABX6 R-SSC-6800334 https://reactome.org/PathwayBrowser/#/R-SSC-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG IEA Sus scrofa A0A287ABY1 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287ABY3 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287ABY3 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287ABY3 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287ABY3 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287ABY4 R-SSC-5624949 https://reactome.org/PathwayBrowser/#/R-SSC-5624949 Assembly of the anterograde IFT train IEA Sus scrofa A0A287ABY4 R-SSC-5624952 https://reactome.org/PathwayBrowser/#/R-SSC-5624952 Assembly of the retrograde IFT train IEA Sus scrofa A0A287ABY4 R-SSC-5625416 https://reactome.org/PathwayBrowser/#/R-SSC-5625416 Anterograde IFT IEA Sus scrofa A0A287ABY4 R-SSC-5625421 https://reactome.org/PathwayBrowser/#/R-SSC-5625421 The anterograde IFT train dissociates IEA Sus scrofa A0A287ABY4 R-SSC-5625424 https://reactome.org/PathwayBrowser/#/R-SSC-5625424 The retrograde IFT train dissociates IEA Sus scrofa A0A287ABY4 R-SSC-5625426 https://reactome.org/PathwayBrowser/#/R-SSC-5625426 Retrograde IFT IEA Sus scrofa A0A287ABZ8 R-SSC-3318486 https://reactome.org/PathwayBrowser/#/R-SSC-3318486 KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 IEA Sus scrofa A0A287ABZ8 R-SSC-6805620 https://reactome.org/PathwayBrowser/#/R-SSC-6805620 KAT6A and PML bind TP53 IEA Sus scrofa A0A287ABZ8 R-SSC-6805638 https://reactome.org/PathwayBrowser/#/R-SSC-6805638 KAT6A acetylates TP53 IEA Sus scrofa A0A287ABZ8 R-SSC-6805650 https://reactome.org/PathwayBrowser/#/R-SSC-6805650 MTA2-NuRD complex deacetylates TP53 IEA Sus scrofa A0A287AC03 R-SSC-430021 https://reactome.org/PathwayBrowser/#/R-SSC-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Sus scrofa A0A287AC15 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A287AC15 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287AC15 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A287AC15 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A287AC24 R-SSC-198955 https://reactome.org/PathwayBrowser/#/R-SSC-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Sus scrofa A0A287AC24 R-SSC-202165 https://reactome.org/PathwayBrowser/#/R-SSC-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Sus scrofa A0A287AC24 R-SSC-202168 https://reactome.org/PathwayBrowser/#/R-SSC-202168 Phosphorylation of ZAP-70 by Lck IEA Sus scrofa A0A287AC24 R-SSC-202174 https://reactome.org/PathwayBrowser/#/R-SSC-202174 Activation of ZAP-70 IEA Sus scrofa A0A287AC24 R-SSC-202214 https://reactome.org/PathwayBrowser/#/R-SSC-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Sus scrofa A0A287AC24 R-SSC-202216 https://reactome.org/PathwayBrowser/#/R-SSC-202216 Phosphorylation of SLP-76 IEA Sus scrofa A0A287AC24 R-SSC-202233 https://reactome.org/PathwayBrowser/#/R-SSC-202233 Inactivation of Lck by Csk IEA Sus scrofa A0A287AC24 R-SSC-202245 https://reactome.org/PathwayBrowser/#/R-SSC-202245 Phosphorylation of TBSMs in LAT IEA Sus scrofa A0A287AC24 R-SSC-202248 https://reactome.org/PathwayBrowser/#/R-SSC-202248 Phosphorylation of PLC-gamma1 IEA Sus scrofa A0A287AC24 R-SSC-202291 https://reactome.org/PathwayBrowser/#/R-SSC-202291 Activation of Lck IEA Sus scrofa A0A287AC24 R-SSC-202307 https://reactome.org/PathwayBrowser/#/R-SSC-202307 Change of PKC theta conformation IEA Sus scrofa A0A287AC24 R-SSC-389758 https://reactome.org/PathwayBrowser/#/R-SSC-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Sus scrofa A0A287AC24 R-SSC-8850326 https://reactome.org/PathwayBrowser/#/R-SSC-8850326 TCR binds self-lipid-based antigen via CD1 IEA Sus scrofa A0A287AC24 R-SSC-8850356 https://reactome.org/PathwayBrowser/#/R-SSC-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Sus scrofa A0A287AC24 R-SSC-8852200 https://reactome.org/PathwayBrowser/#/R-SSC-8852200 Inactivation of LCK by PTPN22 IEA Sus scrofa A0A287AC24 R-SSC-8855381 https://reactome.org/PathwayBrowser/#/R-SSC-8855381 PTPN22 dephosphorylates ZAP70 IEA Sus scrofa A0A287AC28 R-SSC-4724279 https://reactome.org/PathwayBrowser/#/R-SSC-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Sus scrofa A0A287AC28 R-SSC-5661120 https://reactome.org/PathwayBrowser/#/R-SSC-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Sus scrofa A0A287AC43 R-SSC-170986 https://reactome.org/PathwayBrowser/#/R-SSC-170986 Ral-GDS binds to Ras-GTP IEA Sus scrofa A0A287AC43 R-SSC-9660557 https://reactome.org/PathwayBrowser/#/R-SSC-9660557 RAS:GTP binds RAL GDS proteins IEA Sus scrofa A0A287AC44 R-SSC-200421 https://reactome.org/PathwayBrowser/#/R-SSC-200421 Activation of cytosolic AMPK by phosphorylation IEA Sus scrofa A0A287AC44 R-SSC-380942 https://reactome.org/PathwayBrowser/#/R-SSC-380942 LKB1 forms a trimeric complex with STRAD and MO25 IEA Sus scrofa A0A287AC51 R-SSC-2076508 https://reactome.org/PathwayBrowser/#/R-SSC-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Sus scrofa A0A287AC61 R-SSC-6805546 https://reactome.org/PathwayBrowser/#/R-SSC-6805546 Keratin type I binds keratin type II IEA Sus scrofa A0A287AC61 R-SSC-6805573 https://reactome.org/PathwayBrowser/#/R-SSC-6805573 Keratin type I/type II heterodimers form tetramers IEA Sus scrofa A0A287AC61 R-SSC-6806610 https://reactome.org/PathwayBrowser/#/R-SSC-6806610 Keratin filament formation IEA Sus scrofa A0A287AC61 R-SSC-6806613 https://reactome.org/PathwayBrowser/#/R-SSC-6806613 Keratin tetramers bind to form unit length filaments IEA Sus scrofa A0A287AC61 R-SSC-6806629 https://reactome.org/PathwayBrowser/#/R-SSC-6806629 Formation of tonofilament bundles IEA Sus scrofa A0A287AC61 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A287AC61 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287AC61 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A287AC61 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A287AC64 R-SSC-429955 https://reactome.org/PathwayBrowser/#/R-SSC-429955 CCR4-NOT complex deadenylates mRNA IEA Sus scrofa A0A287AC64 R-SSC-6798044 https://reactome.org/PathwayBrowser/#/R-SSC-6798044 BTG2 binds CCR4-NOT complex IEA Sus scrofa A0A287AC69 R-SSC-5674387 https://reactome.org/PathwayBrowser/#/R-SSC-5674387 Phosphorylated MAPKs translocate into the nucleus IEA Sus scrofa A0A287AC69 R-SSC-5675206 https://reactome.org/PathwayBrowser/#/R-SSC-5675206 PEA15 binds MAPK monomers and dimers IEA Sus scrofa A0A287AC85 R-SSC-159101 https://reactome.org/PathwayBrowser/#/R-SSC-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Sus scrofa A0A287AC85 R-SSC-72180 https://reactome.org/PathwayBrowser/#/R-SSC-72180 Cleavage of mRNA at the 3'-end IEA Sus scrofa A0A287AC85 R-SSC-72185 https://reactome.org/PathwayBrowser/#/R-SSC-72185 mRNA polyadenylation IEA Sus scrofa A0A287AC85 R-SSC-8849157 https://reactome.org/PathwayBrowser/#/R-SSC-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Sus scrofa A0A287ACB8 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa A0A287ACB8 R-SSC-420233 https://reactome.org/PathwayBrowser/#/R-SSC-420233 VIP receptors bind VIP IEA Sus scrofa A0A287ACH5 R-SSC-9639287 https://reactome.org/PathwayBrowser/#/R-SSC-9639287 SESN1,2 binds L-leucine and dissociates from GATOR2 IEA Sus scrofa A0A287ACH5 R-SSC-9640195 https://reactome.org/PathwayBrowser/#/R-SSC-9640195 RRAGA,B hydrolyzes GTP IEA Sus scrofa A0A287ACH5 R-SSC-9640237 https://reactome.org/PathwayBrowser/#/R-SSC-9640237 CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 IEA Sus scrofa A0A287ACH5 R-SSC-9640254 https://reactome.org/PathwayBrowser/#/R-SSC-9640254 BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 IEA Sus scrofa A0A287ACH5 R-SSC-9657619 https://reactome.org/PathwayBrowser/#/R-SSC-9657619 CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 IEA Sus scrofa A0A287ACH8 R-SSC-9865449 https://reactome.org/PathwayBrowser/#/R-SSC-9865449 Metallochaperone inserts Cu2+ into MT-CO1 IEA Sus scrofa A0A287ACH8 R-SSC-9865579 https://reactome.org/PathwayBrowser/#/R-SSC-9865579 MT-CO1 and MT-CO2 complexes associate, installing heme moieties IEA Sus scrofa A0A287ACH8 R-SSC-9865630 https://reactome.org/PathwayBrowser/#/R-SSC-9865630 Metallochaperone inserts 2Cu2+ into MT-CO2 IEA Sus scrofa A0A287ACH9 R-SSC-72180 https://reactome.org/PathwayBrowser/#/R-SSC-72180 Cleavage of mRNA at the 3'-end IEA Sus scrofa A0A287ACH9 R-SSC-72185 https://reactome.org/PathwayBrowser/#/R-SSC-72185 mRNA polyadenylation IEA Sus scrofa A0A287ACH9 R-SSC-72231 https://reactome.org/PathwayBrowser/#/R-SSC-72231 Formation of the Cleavage and Polyadenylation Complex IEA Sus scrofa A0A287ACH9 R-SSC-77589 https://reactome.org/PathwayBrowser/#/R-SSC-77589 Recognition of AAUAAA sequence by CPSF IEA Sus scrofa A0A287ACH9 R-SSC-77590 https://reactome.org/PathwayBrowser/#/R-SSC-77590 Recruitment of CstF to the CPSF Bound Pre-mRNA IEA Sus scrofa A0A287ACH9 R-SSC-77591 https://reactome.org/PathwayBrowser/#/R-SSC-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Sus scrofa A0A287ACH9 R-SSC-77592 https://reactome.org/PathwayBrowser/#/R-SSC-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Sus scrofa A0A287ACH9 R-SSC-77593 https://reactome.org/PathwayBrowser/#/R-SSC-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Sus scrofa A0A287ACH9 R-SSC-77594 https://reactome.org/PathwayBrowser/#/R-SSC-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Sus scrofa A0A287ACH9 R-SSC-8849157 https://reactome.org/PathwayBrowser/#/R-SSC-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Sus scrofa A0A287ACI8 R-SSC-8952638 https://reactome.org/PathwayBrowser/#/R-SSC-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287ACI8 R-SSC-8955245 https://reactome.org/PathwayBrowser/#/R-SSC-8955245 CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus IEA Sus scrofa A0A287ACI8 R-SSC-8955285 https://reactome.org/PathwayBrowser/#/R-SSC-8955285 COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287ACI8 R-SSC-8956045 https://reactome.org/PathwayBrowser/#/R-SSC-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287ACM0 R-SSC-8856223 https://reactome.org/PathwayBrowser/#/R-SSC-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Sus scrofa A0A287ACM6 R-SSC-210420 https://reactome.org/PathwayBrowser/#/R-SSC-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Sus scrofa A0A287ACM9 R-SSC-5691507 https://reactome.org/PathwayBrowser/#/R-SSC-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Sus scrofa A0A287ACP7 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287ACS0 R-SSC-9770119 https://reactome.org/PathwayBrowser/#/R-SSC-9770119 Formation of the Spliceosomal E complex IEA Sus scrofa A0A287ACU7 R-SSC-4084980 https://reactome.org/PathwayBrowser/#/R-SSC-4084980 ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) IEA Sus scrofa A0A287ACU7 R-SSC-9846305 https://reactome.org/PathwayBrowser/#/R-SSC-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Sus scrofa A0A287ACV4 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287ACV5 R-SSC-1483186 https://reactome.org/PathwayBrowser/#/R-SSC-1483186 PC is converted to PS by PTDSS1 IEA Sus scrofa A0A287ACW6 R-SSC-870437 https://reactome.org/PathwayBrowser/#/R-SSC-870437 USP9X (FAM) deubiquitinates SMAD4 IEA Sus scrofa A0A287ACW6 R-SSC-870479 https://reactome.org/PathwayBrowser/#/R-SSC-870479 USP9X (FAM) binds to ubiquitinated SMAD4 IEA Sus scrofa A0A287ACW6 R-SSC-8853503 https://reactome.org/PathwayBrowser/#/R-SSC-8853503 UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin IEA Sus scrofa A0A287ACW6 R-SSC-8853514 https://reactome.org/PathwayBrowser/#/R-SSC-8853514 UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin IEA Sus scrofa A0A287ACW6 R-SSC-9018766 https://reactome.org/PathwayBrowser/#/R-SSC-9018766 RHOU binds effectors at the plasma membrane IEA Sus scrofa A0A287ACW6 R-SSC-9018794 https://reactome.org/PathwayBrowser/#/R-SSC-9018794 RHOV binds effectors at the plasma membrane IEA Sus scrofa A0A287ACW6 R-SSC-9033491 https://reactome.org/PathwayBrowser/#/R-SSC-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Sus scrofa A0A287ACW6 R-SSC-9033509 https://reactome.org/PathwayBrowser/#/R-SSC-9033509 USP9X binds Ub:PEX5L IEA Sus scrofa A0A287ACW7 R-SSC-1362408 https://reactome.org/PathwayBrowser/#/R-SSC-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Sus scrofa A0A287ACW7 R-SSC-193054 https://reactome.org/PathwayBrowser/#/R-SSC-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Sus scrofa A0A287ACW7 R-SSC-193065 https://reactome.org/PathwayBrowser/#/R-SSC-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Sus scrofa A0A287ACW7 R-SSC-193101 https://reactome.org/PathwayBrowser/#/R-SSC-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Sus scrofa A0A287ACW7 R-SSC-2395512 https://reactome.org/PathwayBrowser/#/R-SSC-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Sus scrofa A0A287ACX1 R-SSC-177275 https://reactome.org/PathwayBrowser/#/R-SSC-177275 PKA phosphorylates DARPP-32 on Thr34 IEA Sus scrofa A0A287ACX1 R-SSC-177284 https://reactome.org/PathwayBrowser/#/R-SSC-177284 PKA phosphorylates PDE4B IEA Sus scrofa A0A287ACX1 R-SSC-180038 https://reactome.org/PathwayBrowser/#/R-SSC-180038 DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function IEA Sus scrofa A0A287ACX1 R-SSC-180047 https://reactome.org/PathwayBrowser/#/R-SSC-180047 CDK5 phosphorylates DARPP-32 on Thr75 IEA Sus scrofa A0A287ACX1 R-SSC-180073 https://reactome.org/PathwayBrowser/#/R-SSC-180073 DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function IEA Sus scrofa A0A287ACX1 R-SSC-201790 https://reactome.org/PathwayBrowser/#/R-SSC-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Sus scrofa A0A287ACY3 R-SSC-1296127 https://reactome.org/PathwayBrowser/#/R-SSC-1296127 Activation of voltage gated Potassium channels IEA Sus scrofa A0A287ACY9 R-SSC-111439 https://reactome.org/PathwayBrowser/#/R-SSC-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Sus scrofa A0A287ACY9 R-SSC-158441 https://reactome.org/PathwayBrowser/#/R-SSC-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Sus scrofa A0A287ACY9 R-SSC-158447 https://reactome.org/PathwayBrowser/#/R-SSC-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Sus scrofa A0A287ACY9 R-SSC-158481 https://reactome.org/PathwayBrowser/#/R-SSC-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Sus scrofa A0A287ACY9 R-SSC-158484 https://reactome.org/PathwayBrowser/#/R-SSC-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Sus scrofa A0A287ACY9 R-SSC-159046 https://reactome.org/PathwayBrowser/#/R-SSC-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Sus scrofa A0A287ACY9 R-SSC-159050 https://reactome.org/PathwayBrowser/#/R-SSC-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Sus scrofa A0A287ACY9 R-SSC-191830 https://reactome.org/PathwayBrowser/#/R-SSC-191830 snRNP nuclear import and release IEA Sus scrofa A0A287ACY9 R-SSC-2990880 https://reactome.org/PathwayBrowser/#/R-SSC-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Sus scrofa A0A287ACY9 R-SSC-2990882 https://reactome.org/PathwayBrowser/#/R-SSC-2990882 CDK1 phosphorylates NUP98 IEA Sus scrofa A0A287ACY9 R-SSC-3000348 https://reactome.org/PathwayBrowser/#/R-SSC-3000348 RANBP2 SUMOylates SP100 with SUMO2 IEA Sus scrofa A0A287ACY9 R-SSC-3000399 https://reactome.org/PathwayBrowser/#/R-SSC-3000399 RANBP2 SUMOylates SP100 with SUMO1 IEA Sus scrofa A0A287ACY9 R-SSC-3000411 https://reactome.org/PathwayBrowser/#/R-SSC-3000411 RANBP2 SUMOylates PML with SUMO2 IEA Sus scrofa A0A287ACY9 R-SSC-4551649 https://reactome.org/PathwayBrowser/#/R-SSC-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Sus scrofa A0A287ACY9 R-SSC-4551679 https://reactome.org/PathwayBrowser/#/R-SSC-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Sus scrofa A0A287ACY9 R-SSC-4570493 https://reactome.org/PathwayBrowser/#/R-SSC-4570493 RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 IEA Sus scrofa A0A287ACY9 R-SSC-4615872 https://reactome.org/PathwayBrowser/#/R-SSC-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Sus scrofa A0A287ACY9 R-SSC-4615987 https://reactome.org/PathwayBrowser/#/R-SSC-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Sus scrofa A0A287ACY9 R-SSC-4655355 https://reactome.org/PathwayBrowser/#/R-SSC-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Sus scrofa A0A287ACY9 R-SSC-5228508 https://reactome.org/PathwayBrowser/#/R-SSC-5228508 RANBP2 SUMOylates PML with SUMO1 IEA Sus scrofa A0A287ACY9 R-SSC-5228523 https://reactome.org/PathwayBrowser/#/R-SSC-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Sus scrofa A0A287ACY9 R-SSC-5252041 https://reactome.org/PathwayBrowser/#/R-SSC-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Sus scrofa A0A287ACY9 R-SSC-5578744 https://reactome.org/PathwayBrowser/#/R-SSC-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Sus scrofa A0A287ACY9 R-SSC-75097 https://reactome.org/PathwayBrowser/#/R-SSC-75097 Transport of the export-competent mRNP complex through the NPC IEA Sus scrofa A0A287ACY9 R-SSC-75098 https://reactome.org/PathwayBrowser/#/R-SSC-75098 mRNP complex dissociates from cytosolic face of NPC IEA Sus scrofa A0A287ACY9 R-SSC-77587 https://reactome.org/PathwayBrowser/#/R-SSC-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Sus scrofa A0A287ACY9 R-SSC-77594 https://reactome.org/PathwayBrowser/#/R-SSC-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Sus scrofa A0A287ACY9 R-SSC-9618378 https://reactome.org/PathwayBrowser/#/R-SSC-9618378 POM121 binds the Nup107-Nup160 complex IEA Sus scrofa A0A287ACY9 R-SSC-9634169 https://reactome.org/PathwayBrowser/#/R-SSC-9634169 POM121 and NDC1 bind the Nup93 complex IEA Sus scrofa A0A287ACZ4 R-SSC-975814 https://reactome.org/PathwayBrowser/#/R-SSC-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Sus scrofa A0A287AD21 R-SSC-2993763 https://reactome.org/PathwayBrowser/#/R-SSC-2993763 SENP1,2,5 proteolytically process SUMO3 IEA Sus scrofa A0A287AD21 R-SSC-2997616 https://reactome.org/PathwayBrowser/#/R-SSC-2997616 PIAS1,4 SUMOylates BRCA1 with SUMO2,3 IEA Sus scrofa A0A287AD21 R-SSC-3000433 https://reactome.org/PathwayBrowser/#/R-SSC-3000433 SUMOylation of PML with SUMO3 IEA Sus scrofa A0A287AD21 R-SSC-3108203 https://reactome.org/PathwayBrowser/#/R-SSC-3108203 PRC1 SUMOylates CTBP1 with SUMO2,3 IEA Sus scrofa A0A287AD21 R-SSC-3465545 https://reactome.org/PathwayBrowser/#/R-SSC-3465545 PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 IEA Sus scrofa A0A287AD21 R-SSC-4085372 https://reactome.org/PathwayBrowser/#/R-SSC-4085372 PIAS1 SUMOylates SAFB with SUMO2,3 IEA Sus scrofa A0A287AD21 R-SSC-4086059 https://reactome.org/PathwayBrowser/#/R-SSC-4086059 SUMOylation of NPM1 with SUMO2,3 IEA Sus scrofa A0A287AD21 R-SSC-4551616 https://reactome.org/PathwayBrowser/#/R-SSC-4551616 SUMOylation of RPA1 (RPA70) with SUMO2,3 IEA Sus scrofa A0A287AD21 R-SSC-4551738 https://reactome.org/PathwayBrowser/#/R-SSC-4551738 SUMOylation of TDG with SUMO2,3 IEA Sus scrofa A0A287AD21 R-SSC-4551768 https://reactome.org/PathwayBrowser/#/R-SSC-4551768 PIAS4 SUMOylates PARP1 with SUMO2,3 IEA Sus scrofa A0A287AD21 R-SSC-4568914 https://reactome.org/PathwayBrowser/#/R-SSC-4568914 SUMOylation of BLM with SUMO2,3 IEA Sus scrofa A0A287AD21 R-SSC-4570463 https://reactome.org/PathwayBrowser/#/R-SSC-4570463 CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 IEA Sus scrofa A0A287AD21 R-SSC-4570485 https://reactome.org/PathwayBrowser/#/R-SSC-4570485 SUMOylation of Histone H4 with SUMO3 IEA Sus scrofa A0A287AD21 R-SSC-4570553 https://reactome.org/PathwayBrowser/#/R-SSC-4570553 SUMOylation of MDC1 with SUMO2,3 IEA Sus scrofa A0A287AD21 R-SSC-4615839 https://reactome.org/PathwayBrowser/#/R-SSC-4615839 PIAS1 SUMOylates SATB1 with SUMO2,3 IEA Sus scrofa A0A287AD21 R-SSC-4615900 https://reactome.org/PathwayBrowser/#/R-SSC-4615900 PIAS1 SUMOylates SATB2 with SUMO3 IEA Sus scrofa A0A287AD21 R-SSC-4615987 https://reactome.org/PathwayBrowser/#/R-SSC-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Sus scrofa A0A287AD21 R-SSC-4641350 https://reactome.org/PathwayBrowser/#/R-SSC-4641350 PIAS4 SUMOylates TOP2A with SUMO2,3 IEA Sus scrofa A0A287AD21 R-SSC-4655355 https://reactome.org/PathwayBrowser/#/R-SSC-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Sus scrofa A0A287AD21 R-SSC-4719423 https://reactome.org/PathwayBrowser/#/R-SSC-4719423 PIAS2-2 SUMOylates THRA with SUMO3 IEA Sus scrofa A0A287AD21 R-SSC-4719448 https://reactome.org/PathwayBrowser/#/R-SSC-4719448 PIAS1 SUMOylates THRB with SUMO3 IEA Sus scrofa A0A287AD21 R-SSC-4720432 https://reactome.org/PathwayBrowser/#/R-SSC-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Sus scrofa A0A287AD21 R-SSC-4720446 https://reactome.org/PathwayBrowser/#/R-SSC-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Sus scrofa A0A287AD21 R-SSC-4755524 https://reactome.org/PathwayBrowser/#/R-SSC-4755524 SUMOylation of NR1I2 with SUMO3 IEA Sus scrofa A0A287AD21 R-SSC-4755536 https://reactome.org/PathwayBrowser/#/R-SSC-4755536 PIAS3 SUMOylates RELA with SUMO3 IEA Sus scrofa A0A287AD21 R-SSC-6790454 https://reactome.org/PathwayBrowser/#/R-SSC-6790454 SUMOylation of XPC IEA Sus scrofa A0A287AD28 R-SSC-203973 https://reactome.org/PathwayBrowser/#/R-SSC-203973 Vesicle budding IEA Sus scrofa A0A287AD28 R-SSC-204008 https://reactome.org/PathwayBrowser/#/R-SSC-204008 SEC31:SEC13 and v-SNARE recruitment IEA Sus scrofa A0A287AD28 R-SSC-5694409 https://reactome.org/PathwayBrowser/#/R-SSC-5694409 Nucleotide exchange on RAB1 IEA Sus scrofa A0A287AD28 R-SSC-5694413 https://reactome.org/PathwayBrowser/#/R-SSC-5694413 SEC4C,D bind GOSR2 and STX5 IEA Sus scrofa A0A287AD28 R-SSC-5694417 https://reactome.org/PathwayBrowser/#/R-SSC-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Sus scrofa A0A287AD28 R-SSC-5694418 https://reactome.org/PathwayBrowser/#/R-SSC-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Sus scrofa A0A287AD28 R-SSC-5694423 https://reactome.org/PathwayBrowser/#/R-SSC-5694423 NSF and SNAPs bind cis-SNARE complex IEA Sus scrofa A0A287AD28 R-SSC-5694425 https://reactome.org/PathwayBrowser/#/R-SSC-5694425 NSF ATPase activity dissociates cis-SNARE IEA Sus scrofa A0A287AD28 R-SSC-5694446 https://reactome.org/PathwayBrowser/#/R-SSC-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Sus scrofa A0A287AD28 R-SSC-5694522 https://reactome.org/PathwayBrowser/#/R-SSC-5694522 Inner coat assembly and cargo binding IEA Sus scrofa A0A287AD28 R-SSC-5694527 https://reactome.org/PathwayBrowser/#/R-SSC-5694527 Loss of SAR1B GTPase IEA Sus scrofa A0A287AD28 R-SSC-6809011 https://reactome.org/PathwayBrowser/#/R-SSC-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Sus scrofa A0A287AD28 R-SSC-6809014 https://reactome.org/PathwayBrowser/#/R-SSC-6809014 cis-Golgi cis-SNARE binds NSF and SNAPs IEA Sus scrofa A0A287AD28 R-SSC-6809015 https://reactome.org/PathwayBrowser/#/R-SSC-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Sus scrofa A0A287AD28 R-SSC-6811433 https://reactome.org/PathwayBrowser/#/R-SSC-6811433 The COG tethering complex interacts with numerous SNAREs at the Golgi membrane IEA Sus scrofa A0A287AD51 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa A0A287AD51 R-SSC-1981104 https://reactome.org/PathwayBrowser/#/R-SSC-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Sus scrofa A0A287AD51 R-SSC-1981120 https://reactome.org/PathwayBrowser/#/R-SSC-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Sus scrofa A0A287AD51 R-SSC-1981128 https://reactome.org/PathwayBrowser/#/R-SSC-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Sus scrofa A0A287AD51 R-SSC-1981157 https://reactome.org/PathwayBrowser/#/R-SSC-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Sus scrofa A0A287AD51 R-SSC-2002460 https://reactome.org/PathwayBrowser/#/R-SSC-2002460 P4HB binds Collagen chains IEA Sus scrofa A0A287AD51 R-SSC-2089971 https://reactome.org/PathwayBrowser/#/R-SSC-2089971 Secretion of collagens IEA Sus scrofa A0A287AD51 R-SSC-2213210 https://reactome.org/PathwayBrowser/#/R-SSC-2213210 Collagen IX is cross-linked to the surface of collagen type II fibrils IEA Sus scrofa A0A287AD51 R-SSC-2327695 https://reactome.org/PathwayBrowser/#/R-SSC-2327695 Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 IEA Sus scrofa A0A287AD51 R-SSC-2466106 https://reactome.org/PathwayBrowser/#/R-SSC-2466106 BGN binds Collagen types I, VI, (IX) IEA Sus scrofa A0A287AD51 R-SSC-382054 https://reactome.org/PathwayBrowser/#/R-SSC-382054 PDGF binds to extracellular matrix proteins IEA Sus scrofa A0A287AD51 R-SSC-4084903 https://reactome.org/PathwayBrowser/#/R-SSC-4084903 Collagen types VI, IX bind integrin alpha10beta1 IEA Sus scrofa A0A287AD51 R-SSC-4086223 https://reactome.org/PathwayBrowser/#/R-SSC-4086223 Collagen type IX binds integrin alpha11beta1 IEA Sus scrofa A0A287AD51 R-SSC-8944229 https://reactome.org/PathwayBrowser/#/R-SSC-8944229 Association of procollagen type IX IEA Sus scrofa A0A287AD51 R-SSC-8948219 https://reactome.org/PathwayBrowser/#/R-SSC-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A287AD51 R-SSC-8948222 https://reactome.org/PathwayBrowser/#/R-SSC-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287AD51 R-SSC-8948224 https://reactome.org/PathwayBrowser/#/R-SSC-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287AD51 R-SSC-8948228 https://reactome.org/PathwayBrowser/#/R-SSC-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A287AD51 R-SSC-8948231 https://reactome.org/PathwayBrowser/#/R-SSC-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287AD51 R-SSC-8948232 https://reactome.org/PathwayBrowser/#/R-SSC-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Sus scrofa A0A287AD51 R-SSC-8948234 https://reactome.org/PathwayBrowser/#/R-SSC-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Sus scrofa A0A287AD58 R-SSC-8937989 https://reactome.org/PathwayBrowser/#/R-SSC-8937989 RUNX1 binds PRC1 complexes IEA Sus scrofa A0A287AD58 R-SSC-8954082 https://reactome.org/PathwayBrowser/#/R-SSC-8954082 E2F6 binds the PRC1 complex IEA Sus scrofa A0A287AD64 R-SSC-5336453 https://reactome.org/PathwayBrowser/#/R-SSC-5336453 NIPAs transport Mg2+ from extracellular region to cytosol IEA Sus scrofa A0A287ADA1 R-SSC-73596 https://reactome.org/PathwayBrowser/#/R-SSC-73596 dCMP + H2O => dUMP + NH4+ IEA Sus scrofa A0A287ADC2 R-SSC-6791221 https://reactome.org/PathwayBrowser/#/R-SSC-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA IEA Sus scrofa A0A287ADC2 R-SSC-6791222 https://reactome.org/PathwayBrowser/#/R-SSC-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Sus scrofa A0A287ADC2 R-SSC-6791227 https://reactome.org/PathwayBrowser/#/R-SSC-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Sus scrofa A0A287ADD0 R-SSC-9770119 https://reactome.org/PathwayBrowser/#/R-SSC-9770119 Formation of the Spliceosomal E complex IEA Sus scrofa A0A287ADD0 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A287ADD0 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287ADD0 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A287ADD0 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A287ADD1 R-SSC-6791221 https://reactome.org/PathwayBrowser/#/R-SSC-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA IEA Sus scrofa A0A287ADD1 R-SSC-6791222 https://reactome.org/PathwayBrowser/#/R-SSC-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Sus scrofa A0A287ADD1 R-SSC-6791227 https://reactome.org/PathwayBrowser/#/R-SSC-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Sus scrofa A0A287ADD9 R-SSC-8854329 https://reactome.org/PathwayBrowser/#/R-SSC-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Sus scrofa A0A287ADE1 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287ADE6 R-SSC-156808 https://reactome.org/PathwayBrowser/#/R-SSC-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Sus scrofa A0A287ADE6 R-SSC-156823 https://reactome.org/PathwayBrowser/#/R-SSC-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Sus scrofa A0A287ADE6 R-SSC-157849 https://reactome.org/PathwayBrowser/#/R-SSC-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Sus scrofa A0A287ADE6 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A287ADE6 R-SSC-6791221 https://reactome.org/PathwayBrowser/#/R-SSC-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA IEA Sus scrofa A0A287ADE6 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa A0A287ADE6 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A287ADE6 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A287ADE6 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A287ADE6 R-SSC-72676 https://reactome.org/PathwayBrowser/#/R-SSC-72676 eIF3 and eIF1A bind to the 40S subunit IEA Sus scrofa A0A287ADE6 R-SSC-72691 https://reactome.org/PathwayBrowser/#/R-SSC-72691 Formation of the 43S pre-initiation complex IEA Sus scrofa A0A287ADE6 R-SSC-72697 https://reactome.org/PathwayBrowser/#/R-SSC-72697 Start codon recognition IEA Sus scrofa A0A287ADE6 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A287ADE6 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A287ADE6 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A287ADE6 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A287ADE6 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A287ADE7 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287ADE7 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287ADE7 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287ADE7 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287ADE7 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287ADE7 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287ADE7 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287ADE7 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287ADE7 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287ADE7 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287ADE7 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287ADE7 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287ADE7 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287ADE7 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287ADE7 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287ADE7 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287ADE7 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287ADE7 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287ADE7 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287ADE7 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287ADE7 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287ADE7 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287ADE7 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287ADE7 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287ADE7 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287ADE7 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287ADE7 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287ADE7 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287ADE7 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287ADE7 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287ADE7 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287ADE7 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287ADE7 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287ADE7 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287ADE7 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287ADE7 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287ADE7 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287ADE7 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287ADE7 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287ADE7 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287ADE7 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287ADE7 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287ADE7 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287ADE7 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287ADE7 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287ADE7 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287ADE7 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287ADF0 R-SSC-1524182 https://reactome.org/PathwayBrowser/#/R-SSC-1524182 Activated PLC gamma dissociates from the PDGF receptor IEA Sus scrofa A0A287ADF0 R-SSC-1524186 https://reactome.org/PathwayBrowser/#/R-SSC-1524186 Phosphorylation of PLCgamma by PDGFR IEA Sus scrofa A0A287ADF0 R-SSC-186765 https://reactome.org/PathwayBrowser/#/R-SSC-186765 PLC-gamma binds to the active receptor IEA Sus scrofa A0A287ADF0 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa A0A287ADF0 R-SSC-186778 https://reactome.org/PathwayBrowser/#/R-SSC-186778 SHP2 binds to the active receptor IEA Sus scrofa A0A287ADF0 R-SSC-186780 https://reactome.org/PathwayBrowser/#/R-SSC-186780 PI3-kinase binds to the active receptor IEA Sus scrofa A0A287ADF0 R-SSC-186786 https://reactome.org/PathwayBrowser/#/R-SSC-186786 Autophosphorylation of PDGF beta receptors IEA Sus scrofa A0A287ADF0 R-SSC-186798 https://reactome.org/PathwayBrowser/#/R-SSC-186798 GAP binds to PDGF-beta receptors only IEA Sus scrofa A0A287ADF0 R-SSC-186800 https://reactome.org/PathwayBrowser/#/R-SSC-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Sus scrofa A0A287ADF0 R-SSC-186819 https://reactome.org/PathwayBrowser/#/R-SSC-186819 SH2 domain of Src binds to the active receptor IEA Sus scrofa A0A287ADF0 R-SSC-186826 https://reactome.org/PathwayBrowser/#/R-SSC-186826 GRB2:SOS1 complex binds to the active receptor IEA Sus scrofa A0A287ADF0 R-SSC-186834 https://reactome.org/PathwayBrowser/#/R-SSC-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Sus scrofa A0A287ADF0 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287ADF0 R-SSC-380780 https://reactome.org/PathwayBrowser/#/R-SSC-380780 Activation of Src IEA Sus scrofa A0A287ADF0 R-SSC-380782 https://reactome.org/PathwayBrowser/#/R-SSC-380782 STAT binds to the active receptor IEA Sus scrofa A0A287ADF0 R-SSC-382052 https://reactome.org/PathwayBrowser/#/R-SSC-382052 p130Cas and C3G bind PDGFR bound Crk IEA Sus scrofa A0A287ADF0 R-SSC-382053 https://reactome.org/PathwayBrowser/#/R-SSC-382053 Translocation of PDGF from ER to Golgi IEA Sus scrofa A0A287ADF0 R-SSC-382054 https://reactome.org/PathwayBrowser/#/R-SSC-382054 PDGF binds to extracellular matrix proteins IEA Sus scrofa A0A287ADF0 R-SSC-382055 https://reactome.org/PathwayBrowser/#/R-SSC-382055 Grb7 binds to the active PDGF receptor IEA Sus scrofa A0A287ADF0 R-SSC-382056 https://reactome.org/PathwayBrowser/#/R-SSC-382056 Crk binds to the active PDGF receptor IEA Sus scrofa A0A287ADF0 R-SSC-382058 https://reactome.org/PathwayBrowser/#/R-SSC-382058 Nck binds to the active PDGF receptor IEA Sus scrofa A0A287ADF0 R-SSC-389083 https://reactome.org/PathwayBrowser/#/R-SSC-389083 Autophosphorylation of PDGF alpha receptors IEA Sus scrofa A0A287ADF0 R-SSC-389086 https://reactome.org/PathwayBrowser/#/R-SSC-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Sus scrofa A0A287ADF0 R-SSC-481007 https://reactome.org/PathwayBrowser/#/R-SSC-481007 Exocytosis of platelet alpha granule contents IEA Sus scrofa A0A287ADF0 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287ADF0 R-SSC-8864036 https://reactome.org/PathwayBrowser/#/R-SSC-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Sus scrofa A0A287ADF0 R-SSC-8865275 https://reactome.org/PathwayBrowser/#/R-SSC-8865275 PDGF-BB clevage by Furin IEA Sus scrofa A0A287ADF0 R-SSC-8865276 https://reactome.org/PathwayBrowser/#/R-SSC-8865276 PDGF-AB clevage by Furin IEA Sus scrofa A0A287ADF0 R-SSC-9674093 https://reactome.org/PathwayBrowser/#/R-SSC-9674093 PDGFRs bind type I TKI IEA Sus scrofa A0A287ADI4 R-SSC-3772430 https://reactome.org/PathwayBrowser/#/R-SSC-3772430 CTNNBIP1 binds beta-catenin IEA Sus scrofa A0A287ADJ1 R-SSC-548831 https://reactome.org/PathwayBrowser/#/R-SSC-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Sus scrofa A0A287ADJ2 R-SSC-5251942 https://reactome.org/PathwayBrowser/#/R-SSC-5251942 Hikeshi binds HSP70s:ATP IEA Sus scrofa A0A287ADJ2 R-SSC-5251955 https://reactome.org/PathwayBrowser/#/R-SSC-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Sus scrofa A0A287ADJ2 R-SSC-5251959 https://reactome.org/PathwayBrowser/#/R-SSC-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Sus scrofa A0A287ADJ2 R-SSC-5252041 https://reactome.org/PathwayBrowser/#/R-SSC-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Sus scrofa A0A287ADJ2 R-SSC-5252079 https://reactome.org/PathwayBrowser/#/R-SSC-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Sus scrofa A0A287ADJ2 R-SSC-6788523 https://reactome.org/PathwayBrowser/#/R-SSC-6788523 NUBPL transfers 4Fe-4S to Complex I subunits IEA Sus scrofa A0A287ADJ2 R-SSC-6788556 https://reactome.org/PathwayBrowser/#/R-SSC-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Sus scrofa A0A287ADJ2 R-SSC-9838035 https://reactome.org/PathwayBrowser/#/R-SSC-9838035 CLPXP binds mitochondrial matrix proteins IEA Sus scrofa A0A287ADJ2 R-SSC-9838081 https://reactome.org/PathwayBrowser/#/R-SSC-9838081 LONP1 degrades mitochondrial matrix proteins IEA Sus scrofa A0A287ADJ2 R-SSC-9838093 https://reactome.org/PathwayBrowser/#/R-SSC-9838093 LONP1 binds mitochondrial matrix proteins IEA Sus scrofa A0A287ADJ2 R-SSC-9838289 https://reactome.org/PathwayBrowser/#/R-SSC-9838289 CLPXP degrades mitochondrial matrix proteins IEA Sus scrofa A0A287ADJ2 R-SSC-9866272 https://reactome.org/PathwayBrowser/#/R-SSC-9866272 2Fe-2S is inserted in UQCRFS1 IEA Sus scrofa A0A287ADK7 R-SSC-9603775 https://reactome.org/PathwayBrowser/#/R-SSC-9603775 PEX3:PEX19:class I PMP dissociates IEA Sus scrofa A0A287ADK7 R-SSC-9603784 https://reactome.org/PathwayBrowser/#/R-SSC-9603784 PEX19:class I PMP binds PEX3 IEA Sus scrofa A0A287ADK7 R-SSC-9603804 https://reactome.org/PathwayBrowser/#/R-SSC-9603804 PEX19 binds class I peroxisomal membrane proteins IEA Sus scrofa A0A287ADL4 R-SSC-6798739 https://reactome.org/PathwayBrowser/#/R-SSC-6798739 Exocytosis of azurophil granule membrane proteins IEA Sus scrofa A0A287ADL5 R-SSC-425822 https://reactome.org/PathwayBrowser/#/R-SSC-425822 K+-independent Li+/Ca2+ exchanger transport IEA Sus scrofa A0A287ADL5 R-SSC-8949688 https://reactome.org/PathwayBrowser/#/R-SSC-8949688 SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Sus scrofa A0A287ADM2 R-SSC-1013012 https://reactome.org/PathwayBrowser/#/R-SSC-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Sus scrofa A0A287ADM2 R-SSC-1013013 https://reactome.org/PathwayBrowser/#/R-SSC-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Sus scrofa A0A287ADM2 R-SSC-1013020 https://reactome.org/PathwayBrowser/#/R-SSC-1013020 Activation of GIRK/Kir3 Channels IEA Sus scrofa A0A287ADM2 R-SSC-112271 https://reactome.org/PathwayBrowser/#/R-SSC-112271 The receptor:G-protein complex dissociates IEA Sus scrofa A0A287ADM2 R-SSC-114552 https://reactome.org/PathwayBrowser/#/R-SSC-114552 Thrombin-activated PARs activate G12/13 IEA Sus scrofa A0A287ADM2 R-SSC-114558 https://reactome.org/PathwayBrowser/#/R-SSC-114558 Thrombin-activated PARs activate Gq IEA Sus scrofa A0A287ADM2 R-SSC-167408 https://reactome.org/PathwayBrowser/#/R-SSC-167408 The high affinity receptor complex binds to G-protein IEA Sus scrofa A0A287ADM2 R-SSC-167419 https://reactome.org/PathwayBrowser/#/R-SSC-167419 The receptor:G-protein complex releases GDP IEA Sus scrofa A0A287ADM2 R-SSC-167429 https://reactome.org/PathwayBrowser/#/R-SSC-167429 The receptor:G-protein complex binds GTP IEA Sus scrofa A0A287ADM2 R-SSC-167433 https://reactome.org/PathwayBrowser/#/R-SSC-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Sus scrofa A0A287ADM2 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa A0A287ADM2 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287ADM2 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287ADM2 R-SSC-381612 https://reactome.org/PathwayBrowser/#/R-SSC-381612 GLP1R binds GLP1 IEA Sus scrofa A0A287ADM2 R-SSC-392187 https://reactome.org/PathwayBrowser/#/R-SSC-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Sus scrofa A0A287ADM2 R-SSC-392195 https://reactome.org/PathwayBrowser/#/R-SSC-392195 Gi activation by P2Y purinoceptor 12 IEA Sus scrofa A0A287ADM2 R-SSC-392202 https://reactome.org/PathwayBrowser/#/R-SSC-392202 Dissociation of the P2Y purinoceptor 12:Gi complex IEA Sus scrofa A0A287ADM2 R-SSC-392295 https://reactome.org/PathwayBrowser/#/R-SSC-392295 Gbeta:gamma recruits PI3K gamma IEA Sus scrofa A0A287ADM2 R-SSC-392300 https://reactome.org/PathwayBrowser/#/R-SSC-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Sus scrofa A0A287ADM2 R-SSC-392870 https://reactome.org/PathwayBrowser/#/R-SSC-392870 Gs activation by prostacyclin receptor IEA Sus scrofa A0A287ADM2 R-SSC-3965444 https://reactome.org/PathwayBrowser/#/R-SSC-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Sus scrofa A0A287ADM2 R-SSC-3965447 https://reactome.org/PathwayBrowser/#/R-SSC-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Sus scrofa A0A287ADM2 R-SSC-396996 https://reactome.org/PathwayBrowser/#/R-SSC-396996 Thrombin-activated PARs binds G-protein Gq IEA Sus scrofa A0A287ADM2 R-SSC-397835 https://reactome.org/PathwayBrowser/#/R-SSC-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Sus scrofa A0A287ADM2 R-SSC-397891 https://reactome.org/PathwayBrowser/#/R-SSC-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Sus scrofa A0A287ADM2 R-SSC-398040 https://reactome.org/PathwayBrowser/#/R-SSC-398040 Gbeta:gamma activation of PLC beta IEA Sus scrofa A0A287ADM2 R-SSC-398193 https://reactome.org/PathwayBrowser/#/R-SSC-398193 PLC beta-mediated PIP2 hydrolysis IEA Sus scrofa A0A287ADM2 R-SSC-400037 https://reactome.org/PathwayBrowser/#/R-SSC-400037 Gi,Go Heterotrimeric G-protein complex dissociates IEA Sus scrofa A0A287ADM2 R-SSC-400092 https://reactome.org/PathwayBrowser/#/R-SSC-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Sus scrofa A0A287ADM2 R-SSC-400097 https://reactome.org/PathwayBrowser/#/R-SSC-400097 G-beta:G-gamma inhibits Adenylate cyclase IEA Sus scrofa A0A287ADM2 R-SSC-418576 https://reactome.org/PathwayBrowser/#/R-SSC-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Sus scrofa A0A287ADM2 R-SSC-420883 https://reactome.org/PathwayBrowser/#/R-SSC-420883 Opsins act as GEFs for G alpha-t IEA Sus scrofa A0A287ADM2 R-SSC-428749 https://reactome.org/PathwayBrowser/#/R-SSC-428749 Activated TP receptor binds G-proten Gq IEA Sus scrofa A0A287ADM2 R-SSC-428750 https://reactome.org/PathwayBrowser/#/R-SSC-428750 Gq activation by TP receptor IEA Sus scrofa A0A287ADM2 R-SSC-428752 https://reactome.org/PathwayBrowser/#/R-SSC-428752 Dissociation of the TP:Gq complex IEA Sus scrofa A0A287ADM2 R-SSC-428909 https://reactome.org/PathwayBrowser/#/R-SSC-428909 Activated TP receptor binds G-protein G13 IEA Sus scrofa A0A287ADM2 R-SSC-428917 https://reactome.org/PathwayBrowser/#/R-SSC-428917 G13 activation by TP receptor IEA Sus scrofa A0A287ADM2 R-SSC-428918 https://reactome.org/PathwayBrowser/#/R-SSC-428918 Dissociation of the TP:G13 complex IEA Sus scrofa A0A287ADM2 R-SSC-432195 https://reactome.org/PathwayBrowser/#/R-SSC-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Sus scrofa A0A287ADM2 R-SSC-500717 https://reactome.org/PathwayBrowser/#/R-SSC-500717 Activation of GRIK3 homomer IEA Sus scrofa A0A287ADM2 R-SSC-6814418 https://reactome.org/PathwayBrowser/#/R-SSC-6814418 PDCL promotes formation of G-beta:G-gamma heterodimers IEA Sus scrofa A0A287ADM2 R-SSC-749446 https://reactome.org/PathwayBrowser/#/R-SSC-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Sus scrofa A0A287ADM2 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287ADM2 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287ADM2 R-SSC-749453 https://reactome.org/PathwayBrowser/#/R-SSC-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Sus scrofa A0A287ADM2 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287ADM2 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287ADM2 R-SSC-750988 https://reactome.org/PathwayBrowser/#/R-SSC-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Sus scrofa A0A287ADM2 R-SSC-750993 https://reactome.org/PathwayBrowser/#/R-SSC-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Sus scrofa A0A287ADM2 R-SSC-751001 https://reactome.org/PathwayBrowser/#/R-SSC-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Sus scrofa A0A287ADM2 R-SSC-751019 https://reactome.org/PathwayBrowser/#/R-SSC-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Sus scrofa A0A287ADM2 R-SSC-751024 https://reactome.org/PathwayBrowser/#/R-SSC-751024 The Ligand:GPCR:Gz complex dissociates IEA Sus scrofa A0A287ADM2 R-SSC-751027 https://reactome.org/PathwayBrowser/#/R-SSC-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Sus scrofa A0A287ADM2 R-SSC-751029 https://reactome.org/PathwayBrowser/#/R-SSC-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Sus scrofa A0A287ADM2 R-SSC-751039 https://reactome.org/PathwayBrowser/#/R-SSC-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Sus scrofa A0A287ADM2 R-SSC-8850560 https://reactome.org/PathwayBrowser/#/R-SSC-8850560 G-protein alpha releases G-protein heterotrimer from PDCL IEA Sus scrofa A0A287ADM2 R-SSC-8964241 https://reactome.org/PathwayBrowser/#/R-SSC-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Sus scrofa A0A287ADM2 R-SSC-8964271 https://reactome.org/PathwayBrowser/#/R-SSC-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Sus scrofa A0A287ADM2 R-SSC-8964317 https://reactome.org/PathwayBrowser/#/R-SSC-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Sus scrofa A0A287ADM2 R-SSC-8964599 https://reactome.org/PathwayBrowser/#/R-SSC-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Sus scrofa A0A287ADM2 R-SSC-8964604 https://reactome.org/PathwayBrowser/#/R-SSC-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Sus scrofa A0A287ADM2 R-SSC-8964605 https://reactome.org/PathwayBrowser/#/R-SSC-8964605 PAK1:ARHGEF6 complex binds G-protein beta-gamma complex IEA Sus scrofa A0A287ADM2 R-SSC-8964614 https://reactome.org/PathwayBrowser/#/R-SSC-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Sus scrofa A0A287ADM2 R-SSC-8964634 https://reactome.org/PathwayBrowser/#/R-SSC-8964634 CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex IEA Sus scrofa A0A287ADM2 R-SSC-8982637 https://reactome.org/PathwayBrowser/#/R-SSC-8982637 Opsins binds G alpha-t IEA Sus scrofa A0A287ADM2 R-SSC-8982640 https://reactome.org/PathwayBrowser/#/R-SSC-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Sus scrofa A0A287ADM2 R-SSC-9021596 https://reactome.org/PathwayBrowser/#/R-SSC-9021596 Membrane estrogen receptors bind SRC IEA Sus scrofa A0A287ADM2 R-SSC-9021600 https://reactome.org/PathwayBrowser/#/R-SSC-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Sus scrofa A0A287ADM2 R-SSC-9021601 https://reactome.org/PathwayBrowser/#/R-SSC-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Sus scrofa A0A287ADM2 R-SSC-9036301 https://reactome.org/PathwayBrowser/#/R-SSC-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Sus scrofa A0A287ADM2 R-SSC-9036307 https://reactome.org/PathwayBrowser/#/R-SSC-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Sus scrofa A0A287ADM2 R-SSC-9728664 https://reactome.org/PathwayBrowser/#/R-SSC-9728664 GLP1R binds GLP1R agonists IEA Sus scrofa A0A287ADM2 R-SSC-9861324 https://reactome.org/PathwayBrowser/#/R-SSC-9861324 ADM:CALCRL:RAMP2:G-alpha(s):GDP:G-beta:G-gamma exchanges GDP for GTP IEA Sus scrofa A0A287ADM4 R-SSC-8953917 https://reactome.org/PathwayBrowser/#/R-SSC-8953917 PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 IEA Sus scrofa A0A287ADM4 R-SSC-8953946 https://reactome.org/PathwayBrowser/#/R-SSC-8953946 PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 IEA Sus scrofa A0A287ADM4 R-SSC-9033235 https://reactome.org/PathwayBrowser/#/R-SSC-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A287ADM4 R-SSC-9033236 https://reactome.org/PathwayBrowser/#/R-SSC-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Sus scrofa A0A287ADM4 R-SSC-9033485 https://reactome.org/PathwayBrowser/#/R-SSC-9033485 PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 IEA Sus scrofa A0A287ADM4 R-SSC-9033491 https://reactome.org/PathwayBrowser/#/R-SSC-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Sus scrofa A0A287ADM4 R-SSC-9033499 https://reactome.org/PathwayBrowser/#/R-SSC-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Sus scrofa A0A287ADM4 R-SSC-9033509 https://reactome.org/PathwayBrowser/#/R-SSC-9033509 USP9X binds Ub:PEX5L IEA Sus scrofa A0A287ADM4 R-SSC-9033514 https://reactome.org/PathwayBrowser/#/R-SSC-9033514 Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A287ADM4 R-SSC-9033516 https://reactome.org/PathwayBrowser/#/R-SSC-9033516 PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Sus scrofa A0A287ADM4 R-SSC-9033527 https://reactome.org/PathwayBrowser/#/R-SSC-9033527 PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 IEA Sus scrofa A0A287ADM4 R-SSC-9033533 https://reactome.org/PathwayBrowser/#/R-SSC-9033533 PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Sus scrofa A0A287ADM4 R-SSC-9664850 https://reactome.org/PathwayBrowser/#/R-SSC-9664850 ATM binds PEX5 IEA Sus scrofa A0A287ADM4 R-SSC-9664855 https://reactome.org/PathwayBrowser/#/R-SSC-9664855 MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 IEA Sus scrofa A0A287ADM4 R-SSC-9664862 https://reactome.org/PathwayBrowser/#/R-SSC-9664862 ATM dimer:PEX5 phosphorylates PEX5 IEA Sus scrofa A0A287ADM4 R-SSC-9664879 https://reactome.org/PathwayBrowser/#/R-SSC-9664879 ATM:PEX5 binds ATM IEA Sus scrofa A0A287ADM4 R-SSC-9664880 https://reactome.org/PathwayBrowser/#/R-SSC-9664880 MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 IEA Sus scrofa A0A287ADM4 R-SSC-9664881 https://reactome.org/PathwayBrowser/#/R-SSC-9664881 NBR1 binds ATM:Ub-p-PEX5:SQSTM1 IEA Sus scrofa A0A287ADM4 R-SSC-9664883 https://reactome.org/PathwayBrowser/#/R-SSC-9664883 ATM:PEX5 translocates from cytosol to peroxisomal membrane IEA Sus scrofa A0A287ADM4 R-SSC-9664888 https://reactome.org/PathwayBrowser/#/R-SSC-9664888 ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 IEA Sus scrofa A0A287ADM4 R-SSC-9664892 https://reactome.org/PathwayBrowser/#/R-SSC-9664892 SQSTM1 binds ATM dimer:Ub-p-PEX5 IEA Sus scrofa A0A287ADM4 R-SSC-9674127 https://reactome.org/PathwayBrowser/#/R-SSC-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Sus scrofa A0A287ADM4 R-SSC-9674131 https://reactome.org/PathwayBrowser/#/R-SSC-9674131 USP30 binds ATM dimer:Ub-p-PEX5 IEA Sus scrofa A0A287ADP0 R-SSC-5173005 https://reactome.org/PathwayBrowser/#/R-SSC-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Sus scrofa A0A287ADP0 R-SSC-5173192 https://reactome.org/PathwayBrowser/#/R-SSC-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Sus scrofa A0A287ADQ2 R-SSC-9913333 https://reactome.org/PathwayBrowser/#/R-SSC-9913333 DGC complex binds laminins IEA Sus scrofa A0A287ADQ2 R-SSC-9913339 https://reactome.org/PathwayBrowser/#/R-SSC-9913339 Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC IEA Sus scrofa A0A287ADQ2 R-SSC-9914537 https://reactome.org/PathwayBrowser/#/R-SSC-9914537 DGC complex binds AGRN and HSPG2 IEA Sus scrofa A0A287ADQ4 R-SSC-9866253 https://reactome.org/PathwayBrowser/#/R-SSC-9866253 apo-UQCRFS1 binds LYRM7 IEA Sus scrofa A0A287ADQ4 R-SSC-9866272 https://reactome.org/PathwayBrowser/#/R-SSC-9866272 2Fe-2S is inserted in UQCRFS1 IEA Sus scrofa A0A287ADR4 R-SSC-109638 https://reactome.org/PathwayBrowser/#/R-SSC-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Sus scrofa A0A287ADR4 R-SSC-109639 https://reactome.org/PathwayBrowser/#/R-SSC-109639 Formation of the closed pre-initiation complex IEA Sus scrofa A0A287ADR4 R-SSC-111264 https://reactome.org/PathwayBrowser/#/R-SSC-111264 Addition of nucleotides between position +11 and +30 IEA Sus scrofa A0A287ADR4 R-SSC-112379 https://reactome.org/PathwayBrowser/#/R-SSC-112379 Recruitment of elongation factors to form elongation complex IEA Sus scrofa A0A287ADR4 R-SSC-112381 https://reactome.org/PathwayBrowser/#/R-SSC-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex IEA Sus scrofa A0A287ADR4 R-SSC-112383 https://reactome.org/PathwayBrowser/#/R-SSC-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Sus scrofa A0A287ADR4 R-SSC-112385 https://reactome.org/PathwayBrowser/#/R-SSC-112385 Addition of nucleotides leads to transcript elongation IEA Sus scrofa A0A287ADR4 R-SSC-112392 https://reactome.org/PathwayBrowser/#/R-SSC-112392 Resumption of elongation after recovery from pausing IEA Sus scrofa A0A287ADR4 R-SSC-112395 https://reactome.org/PathwayBrowser/#/R-SSC-112395 Abortive termination of elongation after arrest IEA Sus scrofa A0A287ADR4 R-SSC-112396 https://reactome.org/PathwayBrowser/#/R-SSC-112396 Separation of elongating transcript from template IEA Sus scrofa A0A287ADR4 R-SSC-113402 https://reactome.org/PathwayBrowser/#/R-SSC-113402 Formation of DSIF:NELF:early elongation complex IEA Sus scrofa A0A287ADR4 R-SSC-113407 https://reactome.org/PathwayBrowser/#/R-SSC-113407 DSIF complex binds to RNA Pol II (hypophosphorylated) IEA Sus scrofa A0A287ADR4 R-SSC-113409 https://reactome.org/PathwayBrowser/#/R-SSC-113409 Abortive termination of early transcription elongation by DSIF:NELF IEA Sus scrofa A0A287ADR4 R-SSC-113411 https://reactome.org/PathwayBrowser/#/R-SSC-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing IEA Sus scrofa A0A287ADR4 R-SSC-113412 https://reactome.org/PathwayBrowser/#/R-SSC-113412 Pol II elongation complex moves on the template as transcript elongates IEA Sus scrofa A0A287ADR4 R-SSC-113413 https://reactome.org/PathwayBrowser/#/R-SSC-113413 TFIIS-mediated recovery of elongation from arrest IEA Sus scrofa A0A287ADR4 R-SSC-113414 https://reactome.org/PathwayBrowser/#/R-SSC-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest IEA Sus scrofa A0A287ADR4 R-SSC-113429 https://reactome.org/PathwayBrowser/#/R-SSC-113429 Elongating transcript encounters a lesion in the template IEA Sus scrofa A0A287ADR4 R-SSC-113430 https://reactome.org/PathwayBrowser/#/R-SSC-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Sus scrofa A0A287ADR4 R-SSC-5578742 https://reactome.org/PathwayBrowser/#/R-SSC-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Sus scrofa A0A287ADR4 R-SSC-6781818 https://reactome.org/PathwayBrowser/#/R-SSC-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Sus scrofa A0A287ADR4 R-SSC-6781824 https://reactome.org/PathwayBrowser/#/R-SSC-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Sus scrofa A0A287ADR4 R-SSC-6781833 https://reactome.org/PathwayBrowser/#/R-SSC-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Sus scrofa A0A287ADR4 R-SSC-6781867 https://reactome.org/PathwayBrowser/#/R-SSC-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Sus scrofa A0A287ADR4 R-SSC-6782004 https://reactome.org/PathwayBrowser/#/R-SSC-6782004 Assembly of the pre-incision complex in TC-NER IEA Sus scrofa A0A287ADR4 R-SSC-6782069 https://reactome.org/PathwayBrowser/#/R-SSC-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Sus scrofa A0A287ADR4 R-SSC-6782131 https://reactome.org/PathwayBrowser/#/R-SSC-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa A0A287ADR4 R-SSC-6782138 https://reactome.org/PathwayBrowser/#/R-SSC-6782138 ERCC5 and RPA bind TC-NER site IEA Sus scrofa A0A287ADR4 R-SSC-6782141 https://reactome.org/PathwayBrowser/#/R-SSC-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Sus scrofa A0A287ADR4 R-SSC-6782204 https://reactome.org/PathwayBrowser/#/R-SSC-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Sus scrofa A0A287ADR4 R-SSC-6782208 https://reactome.org/PathwayBrowser/#/R-SSC-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Sus scrofa A0A287ADR4 R-SSC-6782211 https://reactome.org/PathwayBrowser/#/R-SSC-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Sus scrofa A0A287ADR4 R-SSC-6782224 https://reactome.org/PathwayBrowser/#/R-SSC-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Sus scrofa A0A287ADR4 R-SSC-6782227 https://reactome.org/PathwayBrowser/#/R-SSC-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Sus scrofa A0A287ADR4 R-SSC-6797606 https://reactome.org/PathwayBrowser/#/R-SSC-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Sus scrofa A0A287ADR4 R-SSC-6797616 https://reactome.org/PathwayBrowser/#/R-SSC-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Sus scrofa A0A287ADR4 R-SSC-6803523 https://reactome.org/PathwayBrowser/#/R-SSC-6803523 PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA IEA Sus scrofa A0A287ADR4 R-SSC-6810233 https://reactome.org/PathwayBrowser/#/R-SSC-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Sus scrofa A0A287ADR4 R-SSC-6810235 https://reactome.org/PathwayBrowser/#/R-SSC-6810235 RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain IEA Sus scrofa A0A287ADR4 R-SSC-6810238 https://reactome.org/PathwayBrowser/#/R-SSC-6810238 RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) IEA Sus scrofa A0A287ADR4 R-SSC-6814549 https://reactome.org/PathwayBrowser/#/R-SSC-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Sus scrofa A0A287ADR4 R-SSC-6814555 https://reactome.org/PathwayBrowser/#/R-SSC-6814555 Integrator complex processes the 3' end of snRNA IEA Sus scrofa A0A287ADR4 R-SSC-6814559 https://reactome.org/PathwayBrowser/#/R-SSC-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Sus scrofa A0A287ADR4 R-SSC-6814885 https://reactome.org/PathwayBrowser/#/R-SSC-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Sus scrofa A0A287ADR4 R-SSC-72095 https://reactome.org/PathwayBrowser/#/R-SSC-72095 Internal Methylation of mRNA IEA Sus scrofa A0A287ADR4 R-SSC-72103 https://reactome.org/PathwayBrowser/#/R-SSC-72103 Formation of pre-mRNPs IEA Sus scrofa A0A287ADR4 R-SSC-73946 https://reactome.org/PathwayBrowser/#/R-SSC-73946 Abortive initiation after formation of the first phosphodiester bond IEA Sus scrofa A0A287ADR4 R-SSC-75079 https://reactome.org/PathwayBrowser/#/R-SSC-75079 Formation of AT-AC C complex IEA Sus scrofa A0A287ADR4 R-SSC-75081 https://reactome.org/PathwayBrowser/#/R-SSC-75081 Formation of AT-AC B Complex IEA Sus scrofa A0A287ADR4 R-SSC-75082 https://reactome.org/PathwayBrowser/#/R-SSC-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Sus scrofa A0A287ADR4 R-SSC-75083 https://reactome.org/PathwayBrowser/#/R-SSC-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Sus scrofa A0A287ADR4 R-SSC-75095 https://reactome.org/PathwayBrowser/#/R-SSC-75095 Binding of TFIIE to the growing preinitiation complex IEA Sus scrofa A0A287ADR4 R-SSC-75850 https://reactome.org/PathwayBrowser/#/R-SSC-75850 Addition of the third nucleotide on the nascent transcript IEA Sus scrofa A0A287ADR4 R-SSC-75856 https://reactome.org/PathwayBrowser/#/R-SSC-75856 Abortive Initiation Before Second Transition IEA Sus scrofa A0A287ADR4 R-SSC-75861 https://reactome.org/PathwayBrowser/#/R-SSC-75861 NTP Binds Active Site of RNA Polymerase II IEA Sus scrofa A0A287ADR4 R-SSC-75862 https://reactome.org/PathwayBrowser/#/R-SSC-75862 Fall Back to Closed Pre-initiation Complex IEA Sus scrofa A0A287ADR4 R-SSC-75864 https://reactome.org/PathwayBrowser/#/R-SSC-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Sus scrofa A0A287ADR4 R-SSC-75866 https://reactome.org/PathwayBrowser/#/R-SSC-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Sus scrofa A0A287ADR4 R-SSC-75869 https://reactome.org/PathwayBrowser/#/R-SSC-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Sus scrofa A0A287ADR4 R-SSC-75873 https://reactome.org/PathwayBrowser/#/R-SSC-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Sus scrofa A0A287ADR4 R-SSC-75891 https://reactome.org/PathwayBrowser/#/R-SSC-75891 Abortive Initiation After Second Transition IEA Sus scrofa A0A287ADR4 R-SSC-75949 https://reactome.org/PathwayBrowser/#/R-SSC-75949 RNA Polymerase II Promoter Opening: First Transition IEA Sus scrofa A0A287ADR4 R-SSC-76576 https://reactome.org/PathwayBrowser/#/R-SSC-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Sus scrofa A0A287ADR4 R-SSC-77068 https://reactome.org/PathwayBrowser/#/R-SSC-77068 Activation of GT IEA Sus scrofa A0A287ADR4 R-SSC-77069 https://reactome.org/PathwayBrowser/#/R-SSC-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Sus scrofa A0A287ADR4 R-SSC-77071 https://reactome.org/PathwayBrowser/#/R-SSC-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Sus scrofa A0A287ADR4 R-SSC-77073 https://reactome.org/PathwayBrowser/#/R-SSC-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Sus scrofa A0A287ADR4 R-SSC-77077 https://reactome.org/PathwayBrowser/#/R-SSC-77077 Capping complex formation IEA Sus scrofa A0A287ADR4 R-SSC-77078 https://reactome.org/PathwayBrowser/#/R-SSC-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Sus scrofa A0A287ADR4 R-SSC-77081 https://reactome.org/PathwayBrowser/#/R-SSC-77081 Formation of the CE:GMP intermediate complex IEA Sus scrofa A0A287ADR4 R-SSC-77083 https://reactome.org/PathwayBrowser/#/R-SSC-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Sus scrofa A0A287ADR4 R-SSC-77085 https://reactome.org/PathwayBrowser/#/R-SSC-77085 Dissociation of transcript with 5'-GMP from GT IEA Sus scrofa A0A287ADR4 R-SSC-77090 https://reactome.org/PathwayBrowser/#/R-SSC-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Sus scrofa A0A287ADR4 R-SSC-77095 https://reactome.org/PathwayBrowser/#/R-SSC-77095 Recognition and binding of the mRNA cap by the cap-binding complex IEA Sus scrofa A0A287ADR4 R-SSC-9012315 https://reactome.org/PathwayBrowser/#/R-SSC-9012315 ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene IEA Sus scrofa A0A287ADR4 R-SSC-9012319 https://reactome.org/PathwayBrowser/#/R-SSC-9012319 p-TEFb phosphorylates serine 2 in RNA polymerase II CTD IEA Sus scrofa A0A287ADR4 R-SSC-9613494 https://reactome.org/PathwayBrowser/#/R-SSC-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Sus scrofa A0A287ADR4 R-SSC-9613497 https://reactome.org/PathwayBrowser/#/R-SSC-9613497 Unwinding DNA for the nascent transcript IEA Sus scrofa A0A287ADR4 R-SSC-9684118 https://reactome.org/PathwayBrowser/#/R-SSC-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa A0A287ADR4 R-SSC-9770119 https://reactome.org/PathwayBrowser/#/R-SSC-9770119 Formation of the Spliceosomal E complex IEA Sus scrofa A0A287ADR4 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A287ADR4 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287ADR4 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A287ADR4 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A287ADU1 R-SSC-176474 https://reactome.org/PathwayBrowser/#/R-SSC-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP IEA Sus scrofa A0A287ADU1 R-SSC-176585 https://reactome.org/PathwayBrowser/#/R-SSC-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP IEA Sus scrofa A0A287ADU8 R-SSC-9838035 https://reactome.org/PathwayBrowser/#/R-SSC-9838035 CLPXP binds mitochondrial matrix proteins IEA Sus scrofa A0A287ADU8 R-SSC-9838289 https://reactome.org/PathwayBrowser/#/R-SSC-9838289 CLPXP degrades mitochondrial matrix proteins IEA Sus scrofa A0A287ADX4 R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa A0A287ADY7 R-SSC-8855617 https://reactome.org/PathwayBrowser/#/R-SSC-8855617 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 IEA Sus scrofa A0A287ADZ3 R-SSC-8940388 https://reactome.org/PathwayBrowser/#/R-SSC-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Sus scrofa A0A287AE09 R-SSC-1296127 https://reactome.org/PathwayBrowser/#/R-SSC-1296127 Activation of voltage gated Potassium channels IEA Sus scrofa A0A287AE22 R-SSC-6791218 https://reactome.org/PathwayBrowser/#/R-SSC-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Sus scrofa A0A287AE22 R-SSC-6791222 https://reactome.org/PathwayBrowser/#/R-SSC-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Sus scrofa A0A287AE22 R-SSC-9933575 https://reactome.org/PathwayBrowser/#/R-SSC-9933575 MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome IEA Sus scrofa A0A287AE22 R-SSC-9933585 https://reactome.org/PathwayBrowser/#/R-SSC-9933585 RNA exosome in PAXT:PAPOLG:TENT4A,B:ZC3H3:CBCA:polyadenylated m7GpppN-RNA:PABPN1 hydrolyzes RNA IEA Sus scrofa A0A287AE22 R-SSC-9934522 https://reactome.org/PathwayBrowser/#/R-SSC-9934522 NEXT:ZC3H18:CBCA:m7GpppN-RNA binds the RNA exosome IEA Sus scrofa A0A287AE22 R-SSC-9934763 https://reactome.org/PathwayBrowser/#/R-SSC-9934763 The RNA exosome in RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA hydrolyzes RNA IEA Sus scrofa A0A287AE22 R-SSC-9935282 https://reactome.org/PathwayBrowser/#/R-SSC-9935282 NEXT:ZC3H4:CBCA:m7GpppN-RNA binds the RNA exosome IEA Sus scrofa A0A287AE22 R-SSC-9935290 https://reactome.org/PathwayBrowser/#/R-SSC-9935290 The RNA exosome in RNA exosome:NEXT:ZC3H4:WDR82:CBCA:capped RNA hydrolyzes capped RNA IEA Sus scrofa A0A287AE25 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A287AE25 R-SSC-6803063 https://reactome.org/PathwayBrowser/#/R-SSC-6803063 RNASEs bind bacterial LPS, PGN IEA Sus scrofa A0A287AE25 R-SSC-8948027 https://reactome.org/PathwayBrowser/#/R-SSC-8948027 RNASEs bind bacterial phospholipids IEA Sus scrofa A0A287AE28 R-SSC-429955 https://reactome.org/PathwayBrowser/#/R-SSC-429955 CCR4-NOT complex deadenylates mRNA IEA Sus scrofa A0A287AE28 R-SSC-6798044 https://reactome.org/PathwayBrowser/#/R-SSC-6798044 BTG2 binds CCR4-NOT complex IEA Sus scrofa A0A287AE35 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AE36 R-SSC-156826 https://reactome.org/PathwayBrowser/#/R-SSC-156826 Dissociation of L13a from the 60s ribosomal subunit IEA Sus scrofa A0A287AE36 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A287AE36 R-SSC-6791218 https://reactome.org/PathwayBrowser/#/R-SSC-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Sus scrofa A0A287AE36 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A287AE36 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A287AE36 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A287AE36 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A287AE36 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A287AE36 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A287AE36 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A287AE36 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A287AE42 R-SSC-9033235 https://reactome.org/PathwayBrowser/#/R-SSC-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A287AE42 R-SSC-9033236 https://reactome.org/PathwayBrowser/#/R-SSC-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Sus scrofa A0A287AE42 R-SSC-9838035 https://reactome.org/PathwayBrowser/#/R-SSC-9838035 CLPXP binds mitochondrial matrix proteins IEA Sus scrofa A0A287AE42 R-SSC-9838081 https://reactome.org/PathwayBrowser/#/R-SSC-9838081 LONP1 degrades mitochondrial matrix proteins IEA Sus scrofa A0A287AE42 R-SSC-9838093 https://reactome.org/PathwayBrowser/#/R-SSC-9838093 LONP1 binds mitochondrial matrix proteins IEA Sus scrofa A0A287AE42 R-SSC-9838289 https://reactome.org/PathwayBrowser/#/R-SSC-9838289 CLPXP degrades mitochondrial matrix proteins IEA Sus scrofa A0A287AE50 R-SSC-9005980 https://reactome.org/PathwayBrowser/#/R-SSC-9005980 IL21 binds IL21R:JAK1 IEA Sus scrofa A0A287AE50 R-SSC-9006844 https://reactome.org/PathwayBrowser/#/R-SSC-9006844 IL21:IL21R:JAK1 binds IL2RG:JAK3 IEA Sus scrofa A0A287AE50 R-SSC-9006850 https://reactome.org/PathwayBrowser/#/R-SSC-9006850 IL21 receptor JAK phosphorylation IEA Sus scrofa A0A287AE50 R-SSC-9006870 https://reactome.org/PathwayBrowser/#/R-SSC-9006870 IL21 receptor STAT phosphorylation IEA Sus scrofa A0A287AE50 R-SSC-9006873 https://reactome.org/PathwayBrowser/#/R-SSC-9006873 IL21 receptor STAT binding IEA Sus scrofa A0A287AE51 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287AE51 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287AE51 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287AE51 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287AE51 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287AE51 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287AE51 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287AE51 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287AE51 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287AE51 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AE51 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287AE51 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287AE51 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287AE51 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287AE51 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287AE51 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287AE51 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287AE51 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287AE51 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287AE51 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287AE51 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287AE51 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287AE51 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287AE51 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287AE51 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287AE51 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287AE51 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287AE51 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287AE51 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287AE51 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287AE51 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287AE51 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287AE51 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287AE51 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287AE51 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287AE51 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287AE51 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287AE51 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287AE51 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287AE51 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287AE51 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287AE51 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287AE51 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287AE51 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287AE51 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287AE51 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287AE51 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287AE54 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A287AE54 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287AE54 R-SSC-70420 https://reactome.org/PathwayBrowser/#/R-SSC-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Sus scrofa A0A287AE60 R-SSC-1226094 https://reactome.org/PathwayBrowser/#/R-SSC-1226094 Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex IEA Sus scrofa A0A287AE60 R-SSC-1226095 https://reactome.org/PathwayBrowser/#/R-SSC-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Sus scrofa A0A287AE60 R-SSC-1227670 https://reactome.org/PathwayBrowser/#/R-SSC-1227670 Recruitment of HDAC1 by p130 (RBL2) IEA Sus scrofa A0A287AE60 R-SSC-1227671 https://reactome.org/PathwayBrowser/#/R-SSC-1227671 Recruitment of HDAC1 by p107 (RBL1) IEA Sus scrofa A0A287AE60 R-SSC-1362261 https://reactome.org/PathwayBrowser/#/R-SSC-1362261 p130 (RBL2) associates with MuvB to form DREAM complex IEA Sus scrofa A0A287AE60 R-SSC-1363303 https://reactome.org/PathwayBrowser/#/R-SSC-1363303 p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 IEA Sus scrofa A0A287AE60 R-SSC-1363311 https://reactome.org/PathwayBrowser/#/R-SSC-1363311 p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 IEA Sus scrofa A0A287AE60 R-SSC-2127257 https://reactome.org/PathwayBrowser/#/R-SSC-2127257 SMAD2/3:SMAD4 heterotrimer forms a complex with RBL1, E2F4/5 and DP1/2 IEA Sus scrofa A0A287AE60 R-SSC-8954056 https://reactome.org/PathwayBrowser/#/R-SSC-8954056 E2F6 binds TFDP2 IEA Sus scrofa A0A287AE60 R-SSC-8954082 https://reactome.org/PathwayBrowser/#/R-SSC-8954082 E2F6 binds the PRC1 complex IEA Sus scrofa A0A287AE60 R-SSC-9018017 https://reactome.org/PathwayBrowser/#/R-SSC-9018017 RB1 binds and inhibits E2F1/2/3:DP1/2 complexes IEA Sus scrofa A0A287AE63 R-SSC-4332236 https://reactome.org/PathwayBrowser/#/R-SSC-4332236 CBL neddylates TGFBR2 IEA Sus scrofa A0A287AE63 R-SSC-5690808 https://reactome.org/PathwayBrowser/#/R-SSC-5690808 UCHL3, SENP8 cleave NEDD8 IEA Sus scrofa A0A287AE63 R-SSC-5691108 https://reactome.org/PathwayBrowser/#/R-SSC-5691108 SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 IEA Sus scrofa A0A287AE63 R-SSC-5691176 https://reactome.org/PathwayBrowser/#/R-SSC-5691176 NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) IEA Sus scrofa A0A287AE63 R-SSC-8863723 https://reactome.org/PathwayBrowser/#/R-SSC-8863723 COP9 and TOR1 deneddylate STON2 IEA Sus scrofa A0A287AE63 R-SSC-8863727 https://reactome.org/PathwayBrowser/#/R-SSC-8863727 STON2 is neddylated IEA Sus scrofa A0A287AE63 R-SSC-8951644 https://reactome.org/PathwayBrowser/#/R-SSC-8951644 Release of mature NEDD8 IEA Sus scrofa A0A287AE63 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AE63 R-SSC-8952626 https://reactome.org/PathwayBrowser/#/R-SSC-8952626 AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AE63 R-SSC-8952631 https://reactome.org/PathwayBrowser/#/R-SSC-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AE63 R-SSC-8952638 https://reactome.org/PathwayBrowser/#/R-SSC-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AE63 R-SSC-8956025 https://reactome.org/PathwayBrowser/#/R-SSC-8956025 AcM-UBE2M transfers NEDD8 to CUL9:RBX1 IEA Sus scrofa A0A287AE63 R-SSC-8956031 https://reactome.org/PathwayBrowser/#/R-SSC-8956031 NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex IEA Sus scrofa A0A287AE63 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AE63 R-SSC-8956045 https://reactome.org/PathwayBrowser/#/R-SSC-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AE63 R-SSC-8956140 https://reactome.org/PathwayBrowser/#/R-SSC-8956140 NEDD8 and UBD bind NUB1 and the 26S proteasome IEA Sus scrofa A0A287AE63 R-SSC-8956184 https://reactome.org/PathwayBrowser/#/R-SSC-8956184 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates IEA Sus scrofa A0A287AE71 R-SSC-5229283 https://reactome.org/PathwayBrowser/#/R-SSC-5229283 LCNs bind lipids IEA Sus scrofa A0A287AE72 R-SSC-8940388 https://reactome.org/PathwayBrowser/#/R-SSC-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Sus scrofa A0A287AE88 R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Sus scrofa A0A287AE88 R-SSC-6799179 https://reactome.org/PathwayBrowser/#/R-SSC-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Sus scrofa A0A287AE88 R-SSC-6799191 https://reactome.org/PathwayBrowser/#/R-SSC-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Sus scrofa A0A287AE88 R-SSC-6799196 https://reactome.org/PathwayBrowser/#/R-SSC-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Sus scrofa A0A287AE88 R-SSC-6799202 https://reactome.org/PathwayBrowser/#/R-SSC-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Sus scrofa A0A287AE88 R-SSC-6799203 https://reactome.org/PathwayBrowser/#/R-SSC-6799203 IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 IEA Sus scrofa A0A287AE88 R-SSC-6800868 https://reactome.org/PathwayBrowser/#/R-SSC-6800868 NDUF subunits bind to form the IP subcomplex IEA Sus scrofa A0A287AE96 R-SSC-2076611 https://reactome.org/PathwayBrowser/#/R-SSC-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Sus scrofa A0A287AE97 R-SSC-162836 https://reactome.org/PathwayBrowser/#/R-SSC-162836 uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide IEA Sus scrofa A0A287AEB7 R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa A0A287AEB7 R-SSC-9709406 https://reactome.org/PathwayBrowser/#/R-SSC-9709406 CO binds to Cytochrome c oxidase IEA Sus scrofa A0A287AEB7 R-SSC-9865663 https://reactome.org/PathwayBrowser/#/R-SSC-9865663 MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex IEA Sus scrofa A0A287AEC1 R-SSC-2028555 https://reactome.org/PathwayBrowser/#/R-SSC-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Sus scrofa A0A287AEC1 R-SSC-2028583 https://reactome.org/PathwayBrowser/#/R-SSC-2028583 Phosphorylation of YAP by LATS2 IEA Sus scrofa A0A287AEC1 R-SSC-2028589 https://reactome.org/PathwayBrowser/#/R-SSC-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Sus scrofa A0A287AEC1 R-SSC-2028598 https://reactome.org/PathwayBrowser/#/R-SSC-2028598 Phosphorylation of YAP by LATS1 IEA Sus scrofa A0A287AEC1 R-SSC-2028626 https://reactome.org/PathwayBrowser/#/R-SSC-2028626 Phosphorylated MOB1A proteins associate with LATS proteins IEA Sus scrofa A0A287AEC1 R-SSC-2028629 https://reactome.org/PathwayBrowser/#/R-SSC-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Sus scrofa A0A287AEC1 R-SSC-2028635 https://reactome.org/PathwayBrowser/#/R-SSC-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Sus scrofa A0A287AEC1 R-SSC-2028661 https://reactome.org/PathwayBrowser/#/R-SSC-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Sus scrofa A0A287AEC1 R-SSC-2028670 https://reactome.org/PathwayBrowser/#/R-SSC-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Sus scrofa A0A287AEC1 R-SSC-2028673 https://reactome.org/PathwayBrowser/#/R-SSC-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Sus scrofa A0A287AEC1 R-SSC-2028675 https://reactome.org/PathwayBrowser/#/R-SSC-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Sus scrofa A0A287AEC1 R-SSC-2028679 https://reactome.org/PathwayBrowser/#/R-SSC-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Sus scrofa A0A287AEC1 R-SSC-2060328 https://reactome.org/PathwayBrowser/#/R-SSC-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Sus scrofa A0A287AEE2 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287AEE7 R-SSC-1226095 https://reactome.org/PathwayBrowser/#/R-SSC-1226095 Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex IEA Sus scrofa A0A287AEE7 R-SSC-1227671 https://reactome.org/PathwayBrowser/#/R-SSC-1227671 Recruitment of HDAC1 by p107 (RBL1) IEA Sus scrofa A0A287AEE7 R-SSC-1363274 https://reactome.org/PathwayBrowser/#/R-SSC-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Sus scrofa A0A287AEE7 R-SSC-1363311 https://reactome.org/PathwayBrowser/#/R-SSC-1363311 p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 IEA Sus scrofa A0A287AEE7 R-SSC-1363314 https://reactome.org/PathwayBrowser/#/R-SSC-1363314 p107 (RBL1) binds CyclinE/A:CDK2 IEA Sus scrofa A0A287AEE7 R-SSC-2127257 https://reactome.org/PathwayBrowser/#/R-SSC-2127257 SMAD2/3:SMAD4 heterotrimer forms a complex with RBL1, E2F4/5 and DP1/2 IEA Sus scrofa A0A287AEE9 R-SSC-1675824 https://reactome.org/PathwayBrowser/#/R-SSC-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Sus scrofa A0A287AEE9 R-SSC-5624953 https://reactome.org/PathwayBrowser/#/R-SSC-5624953 ARL13B binds INPP5E IEA Sus scrofa A0A287AEE9 R-SSC-5624954 https://reactome.org/PathwayBrowser/#/R-SSC-5624954 INPP5E translocates to the primary cilium IEA Sus scrofa A0A287AEE9 R-SSC-5624956 https://reactome.org/PathwayBrowser/#/R-SSC-5624956 PDE6D binds INPP5E IEA Sus scrofa A0A287AEE9 R-SSC-5638012 https://reactome.org/PathwayBrowser/#/R-SSC-5638012 PDE6D dissociates from ARL13B:INPP5E IEA Sus scrofa A0A287AEF3 R-SSC-139897 https://reactome.org/PathwayBrowser/#/R-SSC-139897 BAD displaces tBID from BCL-2 sequestration IEA Sus scrofa A0A287AEF3 R-SSC-139899 https://reactome.org/PathwayBrowser/#/R-SSC-139899 Sequestration of BAD protein by 14-3-3 IEA Sus scrofa A0A287AEF3 R-SSC-139905 https://reactome.org/PathwayBrowser/#/R-SSC-139905 Translocation of activated BAD protein to mitochondria IEA Sus scrofa A0A287AEF3 R-SSC-139906 https://reactome.org/PathwayBrowser/#/R-SSC-139906 Activation of BAD by calcineurin IEA Sus scrofa A0A287AEF3 R-SSC-205075 https://reactome.org/PathwayBrowser/#/R-SSC-205075 JNK phosphorylates BIM, BAD and other targets IEA Sus scrofa A0A287AEF3 R-SSC-508162 https://reactome.org/PathwayBrowser/#/R-SSC-508162 BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL IEA Sus scrofa A0A287AEF3 R-SSC-508163 https://reactome.org/PathwayBrowser/#/R-SSC-508163 BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 IEA Sus scrofa A0A287AEF4 R-SSC-1475028 https://reactome.org/PathwayBrowser/#/R-SSC-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Sus scrofa A0A287AEF4 R-SSC-1475032 https://reactome.org/PathwayBrowser/#/R-SSC-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Sus scrofa A0A287AEF8 R-SSC-3215448 https://reactome.org/PathwayBrowser/#/R-SSC-3215448 SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity IEA Sus scrofa A0A287AEF8 R-SSC-5205799 https://reactome.org/PathwayBrowser/#/R-SSC-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Sus scrofa A0A287AEF8 R-SSC-5205861 https://reactome.org/PathwayBrowser/#/R-SSC-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Sus scrofa A0A287AEF8 R-SSC-8938217 https://reactome.org/PathwayBrowser/#/R-SSC-8938217 RUNX1 binds the SWI/SNF complex IEA Sus scrofa A0A287AEF8 R-SSC-9932437 https://reactome.org/PathwayBrowser/#/R-SSC-9932437 ARID1 binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1 IEA Sus scrofa A0A287AEF8 R-SSC-9932836 https://reactome.org/PathwayBrowser/#/R-SSC-9932836 DPF1,2,3 binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1 IEA Sus scrofa A0A287AEF8 R-SSC-9933238 https://reactome.org/PathwayBrowser/#/R-SSC-9933238 SS18-containing ATPase complex binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1:DPF1,2,3 IEA Sus scrofa A0A287AEG6 R-SSC-399711 https://reactome.org/PathwayBrowser/#/R-SSC-399711 Activation of Ca impermeable AMPA receptors IEA Sus scrofa A0A287AEG6 R-SSC-416639 https://reactome.org/PathwayBrowser/#/R-SSC-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Sus scrofa A0A287AEG6 R-SSC-416985 https://reactome.org/PathwayBrowser/#/R-SSC-416985 Trafficking of GluR2-containing AMPA receptors to synapse IEA Sus scrofa A0A287AEG6 R-SSC-420975 https://reactome.org/PathwayBrowser/#/R-SSC-420975 Ca impermeable AMPA receptor ligand binding IEA Sus scrofa A0A287AEG6 R-SSC-421007 https://reactome.org/PathwayBrowser/#/R-SSC-421007 Endocytosis of Ca impermeable AMPA receptors IEA Sus scrofa A0A287AEG6 R-SSC-438037 https://reactome.org/PathwayBrowser/#/R-SSC-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Sus scrofa A0A287AEH0 R-SSC-1168640 https://reactome.org/PathwayBrowser/#/R-SSC-1168640 Ubiquitinated IkB is degraded IEA Sus scrofa A0A287AEH0 R-SSC-1234159 https://reactome.org/PathwayBrowser/#/R-SSC-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Sus scrofa A0A287AEH0 R-SSC-1236970 https://reactome.org/PathwayBrowser/#/R-SSC-1236970 Proteasomal clevage of exogenous antigen (26S proteasome catalyst) IEA Sus scrofa A0A287AEH0 R-SSC-1504193 https://reactome.org/PathwayBrowser/#/R-SSC-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Sus scrofa A0A287AEH0 R-SSC-174058 https://reactome.org/PathwayBrowser/#/R-SSC-174058 Degradation of multiubiquitinated Cdh1 IEA Sus scrofa A0A287AEH0 R-SSC-174105 https://reactome.org/PathwayBrowser/#/R-SSC-174105 Degradation of multiubiquitinated cell cycle proteins IEA Sus scrofa A0A287AEH0 R-SSC-174202 https://reactome.org/PathwayBrowser/#/R-SSC-174202 Degradation of multiubiquitinated Securin IEA Sus scrofa A0A287AEH0 R-SSC-174255 https://reactome.org/PathwayBrowser/#/R-SSC-174255 Degradation multiubiquitinated Cyclin A IEA Sus scrofa A0A287AEH0 R-SSC-187574 https://reactome.org/PathwayBrowser/#/R-SSC-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Sus scrofa A0A287AEH0 R-SSC-188191 https://reactome.org/PathwayBrowser/#/R-SSC-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Sus scrofa A0A287AEH0 R-SSC-209061 https://reactome.org/PathwayBrowser/#/R-SSC-209061 Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex IEA Sus scrofa A0A287AEH0 R-SSC-2130282 https://reactome.org/PathwayBrowser/#/R-SSC-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Sus scrofa A0A287AEH0 R-SSC-264458 https://reactome.org/PathwayBrowser/#/R-SSC-264458 Proteasome mediated degradation of COP1 IEA Sus scrofa A0A287AEH0 R-SSC-353125 https://reactome.org/PathwayBrowser/#/R-SSC-353125 26S proteosome degrades ODC holoenzyme complex IEA Sus scrofa A0A287AEH0 R-SSC-3640874 https://reactome.org/PathwayBrowser/#/R-SSC-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Sus scrofa A0A287AEH0 R-SSC-450466 https://reactome.org/PathwayBrowser/#/R-SSC-450466 AUF1:mRNA complex is destroyed IEA Sus scrofa A0A287AEH0 R-SSC-4608855 https://reactome.org/PathwayBrowser/#/R-SSC-4608855 PRICKLE1 is degraded by the proteasome IEA Sus scrofa A0A287AEH0 R-SSC-4641256 https://reactome.org/PathwayBrowser/#/R-SSC-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Sus scrofa A0A287AEH0 R-SSC-4641260 https://reactome.org/PathwayBrowser/#/R-SSC-4641260 Ubiquitinated DVL1 is degraded by the proteasome IEA Sus scrofa A0A287AEH0 R-SSC-5362448 https://reactome.org/PathwayBrowser/#/R-SSC-5362448 Hh C-terminal fragments are degraded by the proteasome IEA Sus scrofa A0A287AEH0 R-SSC-5607724 https://reactome.org/PathwayBrowser/#/R-SSC-5607724 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex IEA Sus scrofa A0A287AEH0 R-SSC-5607731 https://reactome.org/PathwayBrowser/#/R-SSC-5607731 26S proteasome processes p-7S-p100:RELB to form p52:RELB IEA Sus scrofa A0A287AEH0 R-SSC-5610754 https://reactome.org/PathwayBrowser/#/R-SSC-5610754 GLI3 is partially degraded by the proteasome to yield the GLI3 repressor IEA Sus scrofa A0A287AEH0 R-SSC-5610758 https://reactome.org/PathwayBrowser/#/R-SSC-5610758 GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP IEA Sus scrofa A0A287AEH0 R-SSC-5610760 https://reactome.org/PathwayBrowser/#/R-SSC-5610760 GLI1 is degraded by the proteasome after ubiquitination by ITCH IEA Sus scrofa A0A287AEH0 R-SSC-5635854 https://reactome.org/PathwayBrowser/#/R-SSC-5635854 GLI2,3 are degraded by the proteasome IEA Sus scrofa A0A287AEH0 R-SSC-5635868 https://reactome.org/PathwayBrowser/#/R-SSC-5635868 ub-GLI is degraded by the proteasome IEA Sus scrofa A0A287AEH0 R-SSC-5658430 https://reactome.org/PathwayBrowser/#/R-SSC-5658430 NF1 is degraded by the proteasome IEA Sus scrofa A0A287AEH0 R-SSC-5665854 https://reactome.org/PathwayBrowser/#/R-SSC-5665854 ADRM1:26S proteaseome binds UCHL5 IEA Sus scrofa A0A287AEH0 R-SSC-5665871 https://reactome.org/PathwayBrowser/#/R-SSC-5665871 ADRM1 binds 26S proteasome IEA Sus scrofa A0A287AEH0 R-SSC-5668481 https://reactome.org/PathwayBrowser/#/R-SSC-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Sus scrofa A0A287AEH0 R-SSC-5668520 https://reactome.org/PathwayBrowser/#/R-SSC-5668520 26Sproteasome degrades K48polyUb-NIK IEA Sus scrofa A0A287AEH0 R-SSC-5687112 https://reactome.org/PathwayBrowser/#/R-SSC-5687112 MAPK6 is degraded by the 26S proteasome IEA Sus scrofa A0A287AEH0 R-SSC-5689539 https://reactome.org/PathwayBrowser/#/R-SSC-5689539 ADRM1:26S proteaseome binds USP14 IEA Sus scrofa A0A287AEH0 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A287AEH0 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287AEH0 R-SSC-68825 https://reactome.org/PathwayBrowser/#/R-SSC-68825 Ubiquitinated geminin is degraded by the proteasome IEA Sus scrofa A0A287AEH0 R-SSC-68948 https://reactome.org/PathwayBrowser/#/R-SSC-68948 Ubiquitinated Orc1 is degraded by the proteasome IEA Sus scrofa A0A287AEH0 R-SSC-69016 https://reactome.org/PathwayBrowser/#/R-SSC-69016 Ubiquitinated Cdc6 is degraded by the proteasome IEA Sus scrofa A0A287AEH0 R-SSC-69600 https://reactome.org/PathwayBrowser/#/R-SSC-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Sus scrofa A0A287AEH0 R-SSC-75825 https://reactome.org/PathwayBrowser/#/R-SSC-75825 Proteasome mediated degradation of Cyclin D1 IEA Sus scrofa A0A287AEH0 R-SSC-8850992 https://reactome.org/PathwayBrowser/#/R-SSC-8850992 Proteasome degrades polyubiquitinated PTEN IEA Sus scrofa A0A287AEH0 R-SSC-8852354 https://reactome.org/PathwayBrowser/#/R-SSC-8852354 GTSE1 facilitates proteasome-mediated degradation of TP53 IEA Sus scrofa A0A287AEH0 R-SSC-8854044 https://reactome.org/PathwayBrowser/#/R-SSC-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Sus scrofa A0A287AEH0 R-SSC-8854071 https://reactome.org/PathwayBrowser/#/R-SSC-8854071 Proteasome-mediated degradation of PolyUb-FBXL7 IEA Sus scrofa A0A287AEH0 R-SSC-8866553 https://reactome.org/PathwayBrowser/#/R-SSC-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Sus scrofa A0A287AEH0 R-SSC-8932355 https://reactome.org/PathwayBrowser/#/R-SSC-8932355 26S proteasome degrades Ub-NFE2L2 IEA Sus scrofa A0A287AEH0 R-SSC-8939801 https://reactome.org/PathwayBrowser/#/R-SSC-8939801 26S proteasome degrades PolyUb-RUNX2 IEA Sus scrofa A0A287AEH0 R-SSC-8952408 https://reactome.org/PathwayBrowser/#/R-SSC-8952408 Polyubiquitinated RUNX3 is degraded by the proteasome IEA Sus scrofa A0A287AEH0 R-SSC-8956140 https://reactome.org/PathwayBrowser/#/R-SSC-8956140 NEDD8 and UBD bind NUB1 and the 26S proteasome IEA Sus scrofa A0A287AEH0 R-SSC-8956184 https://reactome.org/PathwayBrowser/#/R-SSC-8956184 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates IEA Sus scrofa A0A287AEH0 R-SSC-8957265 https://reactome.org/PathwayBrowser/#/R-SSC-8957265 26S proteasome degrades TP73 polyubiquitinated by ITCH IEA Sus scrofa A0A287AEH0 R-SSC-9755303 https://reactome.org/PathwayBrowser/#/R-SSC-9755303 26S proteasome degrades HIFalpha IEA Sus scrofa A0A287AEH0 R-SSC-9755306 https://reactome.org/PathwayBrowser/#/R-SSC-9755306 ub UBXN7 is degraded by the 26S proteasome IEA Sus scrofa A0A287AEH0 R-SSC-9762096 https://reactome.org/PathwayBrowser/#/R-SSC-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Sus scrofa A0A287AEH0 R-SSC-983150 https://reactome.org/PathwayBrowser/#/R-SSC-983150 Proteasomal cleavage of substrate IEA Sus scrofa A0A287AEH0 R-SSC-9907992 https://reactome.org/PathwayBrowser/#/R-SSC-9907992 PSMD11 binds PSMD7:PSMD12:PSMD13:PSMD14 IEA Sus scrofa A0A287AEH0 R-SSC-9907998 https://reactome.org/PathwayBrowser/#/R-SSC-9907998 Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 IEA Sus scrofa A0A287AEH0 R-SSC-9908019 https://reactome.org/PathwayBrowser/#/R-SSC-9908019 Formation of the 19S regulatory particle lid IEA Sus scrofa A0A287AEH0 R-SSC-9908026 https://reactome.org/PathwayBrowser/#/R-SSC-9908026 Formation of the 19S regulatory particle precursor IEA Sus scrofa A0A287AEH0 R-SSC-9934893 https://reactome.org/PathwayBrowser/#/R-SSC-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 IEA Sus scrofa A0A287AEK2 R-SSC-111925 https://reactome.org/PathwayBrowser/#/R-SSC-111925 cAMP induces dissociation of inactive PKA tetramers IEA Sus scrofa A0A287AEK2 R-SSC-5610749 https://reactome.org/PathwayBrowser/#/R-SSC-5610749 cAMP dissociates PKA, promoting GLI processing IEA Sus scrofa A0A287AEK2 R-SSC-8951727 https://reactome.org/PathwayBrowser/#/R-SSC-8951727 cAMP binds PKA tetramer IEA Sus scrofa A0A287AEK2 R-SSC-992708 https://reactome.org/PathwayBrowser/#/R-SSC-992708 Dual-specific AKAPs bind type I and II PKA regulatory subunits IEA Sus scrofa A0A287AEN1 R-SSC-5173005 https://reactome.org/PathwayBrowser/#/R-SSC-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Sus scrofa A0A287AEN1 R-SSC-5173192 https://reactome.org/PathwayBrowser/#/R-SSC-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Sus scrofa A0A287AEN9 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A287AEP5 R-SSC-5686625 https://reactome.org/PathwayBrowser/#/R-SSC-5686625 LAIR1 binds collagen IEA Sus scrofa A0A287AEP5 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A287AEP5 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A287AEQ3 R-SSC-9009065 https://reactome.org/PathwayBrowser/#/R-SSC-9009065 FOXA1 and GATA3 bind to CCND1 promoter IEA Sus scrofa A0A287AEQ3 R-SSC-9009371 https://reactome.org/PathwayBrowser/#/R-SSC-9009371 Binding of AP1 transcriptional activator complexes to CCND1 promoter IEA Sus scrofa A0A287AEQ3 R-SSC-9009526 https://reactome.org/PathwayBrowser/#/R-SSC-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa A0A287AEQ3 R-SSC-9009536 https://reactome.org/PathwayBrowser/#/R-SSC-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Sus scrofa A0A287AEQ3 R-SSC-9009541 https://reactome.org/PathwayBrowser/#/R-SSC-9009541 ESR1 binds to TFF1 gene promoter IEA Sus scrofa A0A287AEQ3 R-SSC-9018499 https://reactome.org/PathwayBrowser/#/R-SSC-9018499 ESR1:ESTG and EP300 are recruited to TFF3 promoter IEA Sus scrofa A0A287AEQ3 R-SSC-9023860 https://reactome.org/PathwayBrowser/#/R-SSC-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Sus scrofa A0A287AEQ3 R-SSC-9023861 https://reactome.org/PathwayBrowser/#/R-SSC-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa A0A287AEQ3 R-SSC-9038163 https://reactome.org/PathwayBrowser/#/R-SSC-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Sus scrofa A0A287AEQ4 R-SSC-9664867 https://reactome.org/PathwayBrowser/#/R-SSC-9664867 NBR1 binds MAP1LC3B IEA Sus scrofa A0A287AEQ4 R-SSC-9664880 https://reactome.org/PathwayBrowser/#/R-SSC-9664880 MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 IEA Sus scrofa A0A287AEQ4 R-SSC-9664881 https://reactome.org/PathwayBrowser/#/R-SSC-9664881 NBR1 binds ATM:Ub-p-PEX5:SQSTM1 IEA Sus scrofa A0A287AEQ9 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287AER5 R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa A0A287AES3 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AES5 R-SSC-372819 https://reactome.org/PathwayBrowser/#/R-SSC-372819 PCK2 phosphorylates OA to yield PEP IEA Sus scrofa A0A287AET1 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa A0A287AET1 R-SSC-444654 https://reactome.org/PathwayBrowser/#/R-SSC-444654 G-protein coupled bile acid receptor binds lithocholic acid IEA Sus scrofa A0A287AET4 R-SSC-435171 https://reactome.org/PathwayBrowser/#/R-SSC-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Sus scrofa A0A287AET4 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A287AET4 R-SSC-6800426 https://reactome.org/PathwayBrowser/#/R-SSC-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Sus scrofa A0A287AET6 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A287AET6 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A287AET6 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A287AET6 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A287AET6 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A287AET6 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A287AET6 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A287AET6 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A287AET6 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A287AET6 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287AET6 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A287AET6 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A287AET6 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287AET6 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A287AET6 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287AET6 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287AET6 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287AET6 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287AET6 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287AET6 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A287AET6 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A287AEV2 R-SSC-1855158 https://reactome.org/PathwayBrowser/#/R-SSC-1855158 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol IEA Sus scrofa A0A287AEV2 R-SSC-1855193 https://reactome.org/PathwayBrowser/#/R-SSC-1855193 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol IEA Sus scrofa A0A287AEV2 R-SSC-1855194 https://reactome.org/PathwayBrowser/#/R-SSC-1855194 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol IEA Sus scrofa A0A287AEV2 R-SSC-1855223 https://reactome.org/PathwayBrowser/#/R-SSC-1855223 I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol IEA Sus scrofa A0A287AEV2 R-SSC-1855227 https://reactome.org/PathwayBrowser/#/R-SSC-1855227 IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol IEA Sus scrofa A0A287AEW1 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287AEW3 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A287AEW3 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A287AEW3 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A287AEW3 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A287AEW3 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A287AF06 R-SSC-446684 https://reactome.org/PathwayBrowser/#/R-SSC-446684 IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation IEA Sus scrofa A0A287AF06 R-SSC-450337 https://reactome.org/PathwayBrowser/#/R-SSC-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Sus scrofa A0A287AF06 R-SSC-450346 https://reactome.org/PathwayBrowser/#/R-SSC-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Sus scrofa A0A287AF06 R-SSC-450358 https://reactome.org/PathwayBrowser/#/R-SSC-450358 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation IEA Sus scrofa A0A287AF06 R-SSC-936942 https://reactome.org/PathwayBrowser/#/R-SSC-936942 Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 IEA Sus scrofa A0A287AF06 R-SSC-936960 https://reactome.org/PathwayBrowser/#/R-SSC-936960 Activated TRAF6:p-IRAK2 interacts with TAK1 complex IEA Sus scrofa A0A287AF06 R-SSC-936963 https://reactome.org/PathwayBrowser/#/R-SSC-936963 IRAK2 induces TRAF6 oligomerization IEA Sus scrofa A0A287AF06 R-SSC-936986 https://reactome.org/PathwayBrowser/#/R-SSC-936986 Activated TRAF6 synthesizes unanchored polyubiquitin chains IEA Sus scrofa A0A287AF06 R-SSC-936991 https://reactome.org/PathwayBrowser/#/R-SSC-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Sus scrofa A0A287AF06 R-SSC-975097 https://reactome.org/PathwayBrowser/#/R-SSC-975097 Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation IEA Sus scrofa A0A287AF06 R-SSC-975103 https://reactome.org/PathwayBrowser/#/R-SSC-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Sus scrofa A0A287AF06 R-SSC-975147 https://reactome.org/PathwayBrowser/#/R-SSC-975147 Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane IEA Sus scrofa A0A287AF06 R-SSC-975185 https://reactome.org/PathwayBrowser/#/R-SSC-975185 IRAK2 induces TRAF6 oligomerization initiated from endosomal compartments IEA Sus scrofa A0A287AF06 R-SSC-9758604 https://reactome.org/PathwayBrowser/#/R-SSC-9758604 Ubiquitination of IKBKG by TRAF6 IEA Sus scrofa A0A287AF07 R-SSC-5688294 https://reactome.org/PathwayBrowser/#/R-SSC-5688294 SIRT5 deacetylates Cytochrome C IEA Sus scrofa A0A287AF31 R-SSC-2076611 https://reactome.org/PathwayBrowser/#/R-SSC-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Sus scrofa A0A287AF62 R-SSC-8875902 https://reactome.org/PathwayBrowser/#/R-SSC-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Sus scrofa A0A287AF70 R-SSC-2684901 https://reactome.org/PathwayBrowser/#/R-SSC-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Sus scrofa A0A287AF70 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A287AF73 R-SSC-204662 https://reactome.org/PathwayBrowser/#/R-SSC-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Sus scrofa A0A287AF76 R-SSC-1678842 https://reactome.org/PathwayBrowser/#/R-SSC-1678842 Competitive inhibition of translation initiation by ISGylated 4EHP IEA Sus scrofa A0A287AF84 R-SSC-8847875 https://reactome.org/PathwayBrowser/#/R-SSC-8847875 ARF1:GTP binds Golgin TRIP11 IEA Sus scrofa A0A287AF84 R-SSC-8878787 https://reactome.org/PathwayBrowser/#/R-SSC-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Sus scrofa A0A287AF84 R-SSC-8940388 https://reactome.org/PathwayBrowser/#/R-SSC-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Sus scrofa A0A287AF91 R-SSC-8876446 https://reactome.org/PathwayBrowser/#/R-SSC-8876446 p-ULK1 phosphorylates DENND3 IEA Sus scrofa A0A287AF91 R-SSC-8876454 https://reactome.org/PathwayBrowser/#/R-SSC-8876454 DENND3 exchanges GTP for GDP on RAB12 IEA Sus scrofa A0A287AFA5 R-SSC-1678923 https://reactome.org/PathwayBrowser/#/R-SSC-1678923 TLR folding by chaperones GP96 and CNPY3 IEA Sus scrofa A0A287AFA5 R-SSC-1678944 https://reactome.org/PathwayBrowser/#/R-SSC-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex IEA Sus scrofa A0A287AFA5 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa A0A287AFA5 R-SSC-6790038 https://reactome.org/PathwayBrowser/#/R-SSC-6790038 Expression of HSP90B1 IEA Sus scrofa A0A287AFA5 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A287AFB4 R-SSC-1504186 https://reactome.org/PathwayBrowser/#/R-SSC-1504186 DVL recruits GSK3beta:AXIN1 to the receptor complex IEA Sus scrofa A0A287AFB4 R-SSC-201677 https://reactome.org/PathwayBrowser/#/R-SSC-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Sus scrofa A0A287AFB4 R-SSC-201685 https://reactome.org/PathwayBrowser/#/R-SSC-201685 Beta-catenin is released from the destruction complex IEA Sus scrofa A0A287AFB4 R-SSC-3965444 https://reactome.org/PathwayBrowser/#/R-SSC-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Sus scrofa A0A287AFB4 R-SSC-3965447 https://reactome.org/PathwayBrowser/#/R-SSC-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Sus scrofa A0A287AFB4 R-SSC-5099886 https://reactome.org/PathwayBrowser/#/R-SSC-5099886 WNT5A binding to FZD promotes PRICKLE1 degradation IEA Sus scrofa A0A287AFB4 R-SSC-5140741 https://reactome.org/PathwayBrowser/#/R-SSC-5140741 WNT5A binds FZD and ROR receptors IEA Sus scrofa A0A287AFB4 R-SSC-5140747 https://reactome.org/PathwayBrowser/#/R-SSC-5140747 FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner IEA Sus scrofa A0A287AFD9 R-SSC-975340 https://reactome.org/PathwayBrowser/#/R-SSC-975340 GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol IEA Sus scrofa A0A287AFE6 R-SSC-199131 https://reactome.org/PathwayBrowser/#/R-SSC-199131 PVR binds CD226 IEA Sus scrofa A0A287AFE6 R-SSC-199144 https://reactome.org/PathwayBrowser/#/R-SSC-199144 Nectin 2 binds CD226 IEA Sus scrofa A0A287AFF5 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A287AFF5 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287AFF5 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A287AFF5 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A287AFH1 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AFH8 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AFH8 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287AFH8 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AFH8 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AFH8 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AFH8 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AFH8 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287AFH8 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AFH8 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AFI3 R-SSC-9861563 https://reactome.org/PathwayBrowser/#/R-SSC-9861563 CTLH E3 ligase ubiquitinates LDHA IEA Sus scrofa A0A287AFI3 R-SSC-9861640 https://reactome.org/PathwayBrowser/#/R-SSC-9861640 CTLH E3 ligase ubiquitinates PKM-1 IEA Sus scrofa A0A287AFJ1 R-SSC-70606 https://reactome.org/PathwayBrowser/#/R-SSC-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Sus scrofa A0A287AFJ9 R-SSC-947531 https://reactome.org/PathwayBrowser/#/R-SSC-947531 Molybdenum ion transfer onto molybdopterin IEA Sus scrofa A0A287AFK3 R-SSC-939763 https://reactome.org/PathwayBrowser/#/R-SSC-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Sus scrofa A0A287AFK3 R-SSC-947591 https://reactome.org/PathwayBrowser/#/R-SSC-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Sus scrofa A0A287AFK4 R-SSC-5696490 https://reactome.org/PathwayBrowser/#/R-SSC-5696490 CRLF1:CLCF1 binds CNTRF IEA Sus scrofa A0A287AFK4 R-SSC-6783530 https://reactome.org/PathwayBrowser/#/R-SSC-6783530 gp130:JAKs bind CNTFR IEA Sus scrofa A0A287AFK4 R-SSC-6783556 https://reactome.org/PathwayBrowser/#/R-SSC-6783556 LIFR:JAKs bind gp130:JAKs:CNTFR IEA Sus scrofa A0A287AFK4 R-SSC-6783670 https://reactome.org/PathwayBrowser/#/R-SSC-6783670 CRLF1 binds CLCF1 IEA Sus scrofa A0A287AFK4 R-SSC-8950504 https://reactome.org/PathwayBrowser/#/R-SSC-8950504 IL27 binds CRLF1 IEA Sus scrofa A0A287AFK4 R-SSC-8950731 https://reactome.org/PathwayBrowser/#/R-SSC-8950731 CRLF1:IL27 translocates to the extracellular region IEA Sus scrofa A0A287AFL9 R-SSC-109636 https://reactome.org/PathwayBrowser/#/R-SSC-109636 Recognition and Binding of Core Promoter Elements by TFIID IEA Sus scrofa A0A287AFL9 R-SSC-109637 https://reactome.org/PathwayBrowser/#/R-SSC-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Sus scrofa A0A287AFL9 R-SSC-109638 https://reactome.org/PathwayBrowser/#/R-SSC-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Sus scrofa A0A287AFL9 R-SSC-109639 https://reactome.org/PathwayBrowser/#/R-SSC-109639 Formation of the closed pre-initiation complex IEA Sus scrofa A0A287AFL9 R-SSC-6805399 https://reactome.org/PathwayBrowser/#/R-SSC-6805399 TAF1 phosphorylates TP53 IEA Sus scrofa A0A287AFL9 R-SSC-6810233 https://reactome.org/PathwayBrowser/#/R-SSC-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Sus scrofa A0A287AFL9 R-SSC-6810235 https://reactome.org/PathwayBrowser/#/R-SSC-6810235 RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain IEA Sus scrofa A0A287AFL9 R-SSC-6810238 https://reactome.org/PathwayBrowser/#/R-SSC-6810238 RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) IEA Sus scrofa A0A287AFL9 R-SSC-6814549 https://reactome.org/PathwayBrowser/#/R-SSC-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Sus scrofa A0A287AFL9 R-SSC-6814555 https://reactome.org/PathwayBrowser/#/R-SSC-6814555 Integrator complex processes the 3' end of snRNA IEA Sus scrofa A0A287AFL9 R-SSC-6814559 https://reactome.org/PathwayBrowser/#/R-SSC-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Sus scrofa A0A287AFL9 R-SSC-6814885 https://reactome.org/PathwayBrowser/#/R-SSC-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Sus scrofa A0A287AFL9 R-SSC-73946 https://reactome.org/PathwayBrowser/#/R-SSC-73946 Abortive initiation after formation of the first phosphodiester bond IEA Sus scrofa A0A287AFL9 R-SSC-75095 https://reactome.org/PathwayBrowser/#/R-SSC-75095 Binding of TFIIE to the growing preinitiation complex IEA Sus scrofa A0A287AFL9 R-SSC-75850 https://reactome.org/PathwayBrowser/#/R-SSC-75850 Addition of the third nucleotide on the nascent transcript IEA Sus scrofa A0A287AFL9 R-SSC-75856 https://reactome.org/PathwayBrowser/#/R-SSC-75856 Abortive Initiation Before Second Transition IEA Sus scrofa A0A287AFL9 R-SSC-75861 https://reactome.org/PathwayBrowser/#/R-SSC-75861 NTP Binds Active Site of RNA Polymerase II IEA Sus scrofa A0A287AFL9 R-SSC-75862 https://reactome.org/PathwayBrowser/#/R-SSC-75862 Fall Back to Closed Pre-initiation Complex IEA Sus scrofa A0A287AFL9 R-SSC-75864 https://reactome.org/PathwayBrowser/#/R-SSC-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Sus scrofa A0A287AFL9 R-SSC-75866 https://reactome.org/PathwayBrowser/#/R-SSC-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Sus scrofa A0A287AFL9 R-SSC-75869 https://reactome.org/PathwayBrowser/#/R-SSC-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Sus scrofa A0A287AFL9 R-SSC-75873 https://reactome.org/PathwayBrowser/#/R-SSC-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Sus scrofa A0A287AFL9 R-SSC-75949 https://reactome.org/PathwayBrowser/#/R-SSC-75949 RNA Polymerase II Promoter Opening: First Transition IEA Sus scrofa A0A287AFL9 R-SSC-9613494 https://reactome.org/PathwayBrowser/#/R-SSC-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Sus scrofa A0A287AFL9 R-SSC-9613497 https://reactome.org/PathwayBrowser/#/R-SSC-9613497 Unwinding DNA for the nascent transcript IEA Sus scrofa A0A287AFM5 R-SSC-1236943 https://reactome.org/PathwayBrowser/#/R-SSC-1236943 Loading of antigen peptide onto MHC class I molecule IEA Sus scrofa A0A287AFM5 R-SSC-1236954 https://reactome.org/PathwayBrowser/#/R-SSC-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Sus scrofa A0A287AFM5 R-SSC-1236964 https://reactome.org/PathwayBrowser/#/R-SSC-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Sus scrofa A0A287AFM5 R-SSC-1236965 https://reactome.org/PathwayBrowser/#/R-SSC-1236965 Export of peptide loaded MHC class I complex to PM IEA Sus scrofa A0A287AFM5 R-SSC-198955 https://reactome.org/PathwayBrowser/#/R-SSC-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Sus scrofa A0A287AFM5 R-SSC-198958 https://reactome.org/PathwayBrowser/#/R-SSC-198958 KIR2DL2/3 interacting with HLA-C group 1 (Cw4) IEA Sus scrofa A0A287AFM5 R-SSC-199558 https://reactome.org/PathwayBrowser/#/R-SSC-199558 KIR2DL1 interacting with HLA-C group 2 (Cw3) IEA Sus scrofa A0A287AFM5 R-SSC-199566 https://reactome.org/PathwayBrowser/#/R-SSC-199566 KIR3DL1 interacting with HLA Bw4 IEA Sus scrofa A0A287AFM5 R-SSC-199583 https://reactome.org/PathwayBrowser/#/R-SSC-199583 KIR2DS2 interacting with HLA-C group 1 (Cw3) IEA Sus scrofa A0A287AFM5 R-SSC-199587 https://reactome.org/PathwayBrowser/#/R-SSC-199587 KIR2DS1 interacting with HLA-C group 2 (Cw4) IEA Sus scrofa A0A287AFM5 R-SSC-210298 https://reactome.org/PathwayBrowser/#/R-SSC-210298 Interaction of DAP12 and KIR3DS1 IEA Sus scrofa A0A287AFM5 R-SSC-210309 https://reactome.org/PathwayBrowser/#/R-SSC-210309 Interaction of DAP12 and KIR2DS2 IEA Sus scrofa A0A287AFM5 R-SSC-2272753 https://reactome.org/PathwayBrowser/#/R-SSC-2272753 Interaction of DAP12 and KIR2DS4 IEA Sus scrofa A0A287AFM5 R-SSC-2272795 https://reactome.org/PathwayBrowser/#/R-SSC-2272795 Interaction of DAP12 and KIR2DS1 IEA Sus scrofa A0A287AFM5 R-SSC-6798739 https://reactome.org/PathwayBrowser/#/R-SSC-6798739 Exocytosis of azurophil granule membrane proteins IEA Sus scrofa A0A287AFM5 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A287AFM5 R-SSC-8863973 https://reactome.org/PathwayBrowser/#/R-SSC-8863973 Fusion of ERC and phagosome IEA Sus scrofa A0A287AFM5 R-SSC-8951499 https://reactome.org/PathwayBrowser/#/R-SSC-8951499 Loading of antigenic peptides on to class I MHC IEA Sus scrofa A0A287AFM5 R-SSC-983138 https://reactome.org/PathwayBrowser/#/R-SSC-983138 Transport of MHC heterotrimer to ER exit site IEA Sus scrofa A0A287AFM5 R-SSC-983142 https://reactome.org/PathwayBrowser/#/R-SSC-983142 Formation of peptide loading complex (PLC) IEA Sus scrofa A0A287AFM5 R-SSC-983145 https://reactome.org/PathwayBrowser/#/R-SSC-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Sus scrofa A0A287AFM5 R-SSC-983146 https://reactome.org/PathwayBrowser/#/R-SSC-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Sus scrofa A0A287AFM5 R-SSC-983161 https://reactome.org/PathwayBrowser/#/R-SSC-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex IEA Sus scrofa A0A287AFM5 R-SSC-983421 https://reactome.org/PathwayBrowser/#/R-SSC-983421 Journey of cargo through Golgi complex IEA Sus scrofa A0A287AFM5 R-SSC-983422 https://reactome.org/PathwayBrowser/#/R-SSC-983422 Disassembly of COPII coated vesicle IEA Sus scrofa A0A287AFM5 R-SSC-983424 https://reactome.org/PathwayBrowser/#/R-SSC-983424 Budding of COPII coated vesicle IEA Sus scrofa A0A287AFM5 R-SSC-983425 https://reactome.org/PathwayBrowser/#/R-SSC-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Sus scrofa A0A287AFM5 R-SSC-983427 https://reactome.org/PathwayBrowser/#/R-SSC-983427 Expression of peptide bound class I MHC on cell surface IEA Sus scrofa A0A287AFN2 R-SSC-73605 https://reactome.org/PathwayBrowser/#/R-SSC-73605 dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate IEA Sus scrofa A0A287AFN9 R-SSC-1297333 https://reactome.org/PathwayBrowser/#/R-SSC-1297333 Association of Acrosin Heavy and Light Chain IEA Sus scrofa A0A287AFN9 R-SSC-1297354 https://reactome.org/PathwayBrowser/#/R-SSC-1297354 Acrosin Cleavage IEA Sus scrofa A0A287AFQ2 R-SSC-6801242 https://reactome.org/PathwayBrowser/#/R-SSC-6801242 TRIAP1 binds PRELID1, PRELID3A IEA Sus scrofa A0A287AFQ2 R-SSC-6801250 https://reactome.org/PathwayBrowser/#/R-SSC-6801250 TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane IEA Sus scrofa A0A287AFQ4 R-SSC-173709 https://reactome.org/PathwayBrowser/#/R-SSC-173709 C7 binds C5b:C6 IEA Sus scrofa A0A287AFQ4 R-SSC-173720 https://reactome.org/PathwayBrowser/#/R-SSC-173720 C5b:C6:C7 translocates to the plasma membrane IEA Sus scrofa A0A287AFQ4 R-SSC-173723 https://reactome.org/PathwayBrowser/#/R-SSC-173723 C8 binds C5b:C6:C7 IEA Sus scrofa A0A287AFQ4 R-SSC-173725 https://reactome.org/PathwayBrowser/#/R-SSC-173725 C9 binds C5b:C6:C7:C8 IEA Sus scrofa A0A287AFQ4 R-SSC-2530429 https://reactome.org/PathwayBrowser/#/R-SSC-2530429 Formation of soluble VTN:C5b-C9 IEA Sus scrofa A0A287AFQ4 R-SSC-2530445 https://reactome.org/PathwayBrowser/#/R-SSC-2530445 CD59 inhibits MAC formation IEA Sus scrofa A0A287AFQ4 R-SSC-8852580 https://reactome.org/PathwayBrowser/#/R-SSC-8852580 Clusterin binds C5b-C7, C8, C9 IEA Sus scrofa A0A287AFR0 R-SSC-450027 https://reactome.org/PathwayBrowser/#/R-SSC-450027 Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta IEA Sus scrofa A0A287AFR0 R-SSC-450063 https://reactome.org/PathwayBrowser/#/R-SSC-450063 Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit IEA Sus scrofa A0A287AFR0 R-SSC-451900 https://reactome.org/PathwayBrowser/#/R-SSC-451900 IL2RB binds JAK1 IEA Sus scrofa A0A287AFR0 R-SSC-451942 https://reactome.org/PathwayBrowser/#/R-SSC-451942 Within the IL-2R complex JAK3 phosphorylates JAK1 IEA Sus scrofa A0A287AFR0 R-SSC-452091 https://reactome.org/PathwayBrowser/#/R-SSC-452091 Phosphorylation of IL2RB Y338 enables SHC recruitment IEA Sus scrofa A0A287AFR0 R-SSC-452097 https://reactome.org/PathwayBrowser/#/R-SSC-452097 Recruited STAT5 is phosphorylated IEA Sus scrofa A0A287AFR0 R-SSC-452100 https://reactome.org/PathwayBrowser/#/R-SSC-452100 SHC1 bound to IL2 receptor is phosphorylated IEA Sus scrofa A0A287AFR0 R-SSC-452108 https://reactome.org/PathwayBrowser/#/R-SSC-452108 Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment IEA Sus scrofa A0A287AFR0 R-SSC-452122 https://reactome.org/PathwayBrowser/#/R-SSC-452122 JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB IEA Sus scrofa A0A287AFR0 R-SSC-453104 https://reactome.org/PathwayBrowser/#/R-SSC-453104 Phosphorylated SHC1 recruits GRB2:GAB2 IEA Sus scrofa A0A287AFR0 R-SSC-453111 https://reactome.org/PathwayBrowser/#/R-SSC-453111 Phosphorylated SHC recruits GRB2:SOS1 IEA Sus scrofa A0A287AFR0 R-SSC-508247 https://reactome.org/PathwayBrowser/#/R-SSC-508247 Gab2 binds the p85 subunit of Class 1A PI3 kinases IEA Sus scrofa A0A287AFR0 R-SSC-508282 https://reactome.org/PathwayBrowser/#/R-SSC-508282 SYK is a substrate for JAK1 IEA Sus scrofa A0A287AFR0 R-SSC-508292 https://reactome.org/PathwayBrowser/#/R-SSC-508292 SYK binds IL2RB IEA Sus scrofa A0A287AFR0 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287AFR0 R-SSC-8983298 https://reactome.org/PathwayBrowser/#/R-SSC-8983298 IL15 binds IL2RB:JAK1 and IL2RG:JAK3 IEA Sus scrofa A0A287AFR0 R-SSC-8983300 https://reactome.org/PathwayBrowser/#/R-SSC-8983300 IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 IEA Sus scrofa A0A287AFR0 R-SSC-8983335 https://reactome.org/PathwayBrowser/#/R-SSC-8983335 IL15:IL15RA:IL2RB:JAK1:IL2RG:JAK3 translocates from the plasma membrane to the endosome IEA Sus scrofa A0A287AFR0 R-SSC-8983371 https://reactome.org/PathwayBrowser/#/R-SSC-8983371 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 IEA Sus scrofa A0A287AFR0 R-SSC-8983374 https://reactome.org/PathwayBrowser/#/R-SSC-8983374 p-Y-STAT3 and p-STAT5 dissociates from IL15:IL15RA:IL2RB:p-JAK1:IL2RG:p-JAK3:p-Y-STAT3:p-STAT5 IEA Sus scrofa A0A287AFR0 R-SSC-8983378 https://reactome.org/PathwayBrowser/#/R-SSC-8983378 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 IEA Sus scrofa A0A287AFR0 R-SSC-8983384 https://reactome.org/PathwayBrowser/#/R-SSC-8983384 IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 IEA Sus scrofa A0A287AFR0 R-SSC-912527 https://reactome.org/PathwayBrowser/#/R-SSC-912527 SHC1 mediates cytokine-induced phosphorylation of GAB2 IEA Sus scrofa A0A287AFR0 R-SSC-913374 https://reactome.org/PathwayBrowser/#/R-SSC-913374 Phosphorylated SHC1 recruits SHIP IEA Sus scrofa A0A287AFR0 R-SSC-913424 https://reactome.org/PathwayBrowser/#/R-SSC-913424 The SHC1:SHIP1 complex is stabilized by GRB2 IEA Sus scrofa A0A287AFR0 R-SSC-919404 https://reactome.org/PathwayBrowser/#/R-SSC-919404 Phosphorylated STAT5 is released IEA Sus scrofa A0A287AFR2 R-SSC-5693584 https://reactome.org/PathwayBrowser/#/R-SSC-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Sus scrofa A0A287AFR7 R-SSC-445753 https://reactome.org/PathwayBrowser/#/R-SSC-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Sus scrofa A0A287AFR7 R-SSC-446130 https://reactome.org/PathwayBrowser/#/R-SSC-446130 Interleukin-1 receptor type 2 binds Interleukin 1 IEA Sus scrofa A0A287AFR7 R-SSC-446634 https://reactome.org/PathwayBrowser/#/R-SSC-446634 IRAK4 is activated by autophosphorylation IEA Sus scrofa A0A287AFR7 R-SSC-446648 https://reactome.org/PathwayBrowser/#/R-SSC-446648 IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 IEA Sus scrofa A0A287AFR7 R-SSC-446684 https://reactome.org/PathwayBrowser/#/R-SSC-446684 IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation IEA Sus scrofa A0A287AFR7 R-SSC-446692 https://reactome.org/PathwayBrowser/#/R-SSC-446692 IRAK1 binds to MYD88 within the IL1R complex IEA Sus scrofa A0A287AFR7 R-SSC-446694 https://reactome.org/PathwayBrowser/#/R-SSC-446694 IRAK4 phosphorylates IRAK1 IEA Sus scrofa A0A287AFR7 R-SSC-446701 https://reactome.org/PathwayBrowser/#/R-SSC-446701 IRAK4-activated IRAK1 autophosphorylates IEA Sus scrofa A0A287AFR7 R-SSC-446862 https://reactome.org/PathwayBrowser/#/R-SSC-446862 Hyperphosphorylated IRAK1 associates with TRAF6 IEA Sus scrofa A0A287AFR7 R-SSC-446868 https://reactome.org/PathwayBrowser/#/R-SSC-446868 The Interleukin 1 receptor complex binds Tollip IEA Sus scrofa A0A287AFR7 R-SSC-446894 https://reactome.org/PathwayBrowser/#/R-SSC-446894 TRAF6 binding leads to IRAK1:TRAF6 release IEA Sus scrofa A0A287AFR7 R-SSC-448703 https://reactome.org/PathwayBrowser/#/R-SSC-448703 Interleukin-1 family precursors are cleaved by caspase-1 IEA Sus scrofa A0A287AFR7 R-SSC-449058 https://reactome.org/PathwayBrowser/#/R-SSC-449058 Interleukin-1 family are secreted IEA Sus scrofa A0A287AFR7 R-SSC-507719 https://reactome.org/PathwayBrowser/#/R-SSC-507719 p62:MEKK3 binds to TRAF6 IEA Sus scrofa A0A287AFR7 R-SSC-5660663 https://reactome.org/PathwayBrowser/#/R-SSC-5660663 Caspase-8 cleaves IL1B precursor IEA Sus scrofa A0A287AFR9 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AFT4 R-SSC-2029466 https://reactome.org/PathwayBrowser/#/R-SSC-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Sus scrofa A0A287AFT4 R-SSC-2197690 https://reactome.org/PathwayBrowser/#/R-SSC-2197690 Detachment of WASP/WAVE IEA Sus scrofa A0A287AFT4 R-SSC-2197691 https://reactome.org/PathwayBrowser/#/R-SSC-2197691 WIP binds WASP,N-WASP, activating them IEA Sus scrofa A0A287AFT4 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A287AFT4 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A287AFT6 R-SSC-113504 https://reactome.org/PathwayBrowser/#/R-SSC-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Sus scrofa A0A287AFT6 R-SSC-174425 https://reactome.org/PathwayBrowser/#/R-SSC-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Sus scrofa A0A287AFT6 R-SSC-174427 https://reactome.org/PathwayBrowser/#/R-SSC-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Sus scrofa A0A287AFT6 R-SSC-174452 https://reactome.org/PathwayBrowser/#/R-SSC-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Sus scrofa A0A287AFT6 R-SSC-68913 https://reactome.org/PathwayBrowser/#/R-SSC-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Sus scrofa A0A287AFT6 R-SSC-68914 https://reactome.org/PathwayBrowser/#/R-SSC-68914 DNA polymerase alpha:primase binds at the origin IEA Sus scrofa A0A287AFT6 R-SSC-68950 https://reactome.org/PathwayBrowser/#/R-SSC-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Sus scrofa A0A287AFT6 R-SSC-69053 https://reactome.org/PathwayBrowser/#/R-SSC-69053 RFC binding displaces Pol Alpha IEA Sus scrofa A0A287AFT6 R-SSC-69063 https://reactome.org/PathwayBrowser/#/R-SSC-69063 Loading of PCNA - Sliding Clamp Formation IEA Sus scrofa A0A287AFT6 R-SSC-69068 https://reactome.org/PathwayBrowser/#/R-SSC-69068 RFC dissociates after sliding clamp formation IEA Sus scrofa A0A287AFT6 R-SSC-69074 https://reactome.org/PathwayBrowser/#/R-SSC-69074 Formation of Processive Complex IEA Sus scrofa A0A287AFT6 R-SSC-69116 https://reactome.org/PathwayBrowser/#/R-SSC-69116 Formation of Okazaki fragments IEA Sus scrofa A0A287AFT6 R-SSC-69127 https://reactome.org/PathwayBrowser/#/R-SSC-69127 Formation of the Flap Intermediate IEA Sus scrofa A0A287AFT6 R-SSC-69140 https://reactome.org/PathwayBrowser/#/R-SSC-69140 RPA binds to the Flap IEA Sus scrofa A0A287AFT6 R-SSC-69142 https://reactome.org/PathwayBrowser/#/R-SSC-69142 Recruitment of Dna2 endonuclease IEA Sus scrofa A0A287AFT6 R-SSC-69144 https://reactome.org/PathwayBrowser/#/R-SSC-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Sus scrofa A0A287AFT6 R-SSC-69152 https://reactome.org/PathwayBrowser/#/R-SSC-69152 Removal of remaining Flap IEA Sus scrofa A0A287AFT6 R-SSC-9668597 https://reactome.org/PathwayBrowser/#/R-SSC-9668597 DNA polymerase:primase binds G-strand of the telomere IEA Sus scrofa A0A287AFV6 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287AFV6 R-SSC-444606 https://reactome.org/PathwayBrowser/#/R-SSC-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Sus scrofa A0A287AFV6 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287AFV6 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287AFV6 R-SSC-9728723 https://reactome.org/PathwayBrowser/#/R-SSC-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Sus scrofa A0A287AFW3 R-SSC-9660557 https://reactome.org/PathwayBrowser/#/R-SSC-9660557 RAS:GTP binds RAL GDS proteins IEA Sus scrofa A0A287AFX3 R-SSC-109699 https://reactome.org/PathwayBrowser/#/R-SSC-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Sus scrofa A0A287AFX3 R-SSC-190256 https://reactome.org/PathwayBrowser/#/R-SSC-190256 FGFR1c binds to FGF IEA Sus scrofa A0A287AFX3 R-SSC-190265 https://reactome.org/PathwayBrowser/#/R-SSC-190265 FGFR4 binds to FGF IEA Sus scrofa A0A287AFX3 R-SSC-190326 https://reactome.org/PathwayBrowser/#/R-SSC-190326 Autocatalytic phosphorylation of FGFR4 IEA Sus scrofa A0A287AFX3 R-SSC-190429 https://reactome.org/PathwayBrowser/#/R-SSC-190429 Autocatalytic phosphorylation of FGFR1c IEA Sus scrofa A0A287AFX3 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AFX3 R-SSC-5654149 https://reactome.org/PathwayBrowser/#/R-SSC-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Sus scrofa A0A287AFX3 R-SSC-5654151 https://reactome.org/PathwayBrowser/#/R-SSC-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Sus scrofa A0A287AFX3 R-SSC-5654163 https://reactome.org/PathwayBrowser/#/R-SSC-5654163 Activated FGFR4 binds PLCG1 IEA Sus scrofa A0A287AFX3 R-SSC-5654165 https://reactome.org/PathwayBrowser/#/R-SSC-5654165 p-4Y-PLCG1 dissociates from activated FGFR1 IEA Sus scrofa A0A287AFX3 R-SSC-5654167 https://reactome.org/PathwayBrowser/#/R-SSC-5654167 Activated FGFR1 binds PLCG1 IEA Sus scrofa A0A287AFX3 R-SSC-5654169 https://reactome.org/PathwayBrowser/#/R-SSC-5654169 p-4Y-PLCG1 dissociates from activated FGFR4 IEA Sus scrofa A0A287AFX3 R-SSC-5654392 https://reactome.org/PathwayBrowser/#/R-SSC-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A287AFX3 R-SSC-5654418 https://reactome.org/PathwayBrowser/#/R-SSC-5654418 Activated FGFR4 phosphorylates FRS2 IEA Sus scrofa A0A287AFX3 R-SSC-5654422 https://reactome.org/PathwayBrowser/#/R-SSC-5654422 Activated FGFR4 binds FRS2 IEA Sus scrofa A0A287AFX3 R-SSC-5654423 https://reactome.org/PathwayBrowser/#/R-SSC-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Sus scrofa A0A287AFX3 R-SSC-5654425 https://reactome.org/PathwayBrowser/#/R-SSC-5654425 Activated FGFR4 binds SHC1 IEA Sus scrofa A0A287AFX3 R-SSC-5654426 https://reactome.org/PathwayBrowser/#/R-SSC-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A287AFX3 R-SSC-5654428 https://reactome.org/PathwayBrowser/#/R-SSC-5654428 Activated FGFR4 phosphorylates SHC1 IEA Sus scrofa A0A287AFX3 R-SSC-5654560 https://reactome.org/PathwayBrowser/#/R-SSC-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2 IEA Sus scrofa A0A287AFX3 R-SSC-5654566 https://reactome.org/PathwayBrowser/#/R-SSC-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2 IEA Sus scrofa A0A287AFX3 R-SSC-5654569 https://reactome.org/PathwayBrowser/#/R-SSC-5654569 Activated FGFR1 binds FRS2 IEA Sus scrofa A0A287AFX3 R-SSC-5654571 https://reactome.org/PathwayBrowser/#/R-SSC-5654571 Activated FGFR1 binds FRS3 IEA Sus scrofa A0A287AFX3 R-SSC-5654573 https://reactome.org/PathwayBrowser/#/R-SSC-5654573 Activated FGFR1 binds SHC1 IEA Sus scrofa A0A287AFX3 R-SSC-5654575 https://reactome.org/PathwayBrowser/#/R-SSC-5654575 Activated FGFR1 phosphorylates FRS2 IEA Sus scrofa A0A287AFX3 R-SSC-5654578 https://reactome.org/PathwayBrowser/#/R-SSC-5654578 Activated FGFR1 phosphorylates FRS3 IEA Sus scrofa A0A287AFX3 R-SSC-5654582 https://reactome.org/PathwayBrowser/#/R-SSC-5654582 Activated FGFR1 phosphorylates SHC1 IEA Sus scrofa A0A287AFX3 R-SSC-5654584 https://reactome.org/PathwayBrowser/#/R-SSC-5654584 Activated FGFR1:p-FRS bind to PPTN11 IEA Sus scrofa A0A287AFX3 R-SSC-5654586 https://reactome.org/PathwayBrowser/#/R-SSC-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Sus scrofa A0A287AFX3 R-SSC-5654587 https://reactome.org/PathwayBrowser/#/R-SSC-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Sus scrofa A0A287AFX3 R-SSC-5654591 https://reactome.org/PathwayBrowser/#/R-SSC-5654591 Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Sus scrofa A0A287AFX3 R-SSC-5654592 https://reactome.org/PathwayBrowser/#/R-SSC-5654592 Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Sus scrofa A0A287AFX3 R-SSC-5654594 https://reactome.org/PathwayBrowser/#/R-SSC-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Sus scrofa A0A287AFX3 R-SSC-5654596 https://reactome.org/PathwayBrowser/#/R-SSC-5654596 Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Sus scrofa A0A287AFX3 R-SSC-5654597 https://reactome.org/PathwayBrowser/#/R-SSC-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Sus scrofa A0A287AFX3 R-SSC-5654600 https://reactome.org/PathwayBrowser/#/R-SSC-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A287AFX3 R-SSC-5654651 https://reactome.org/PathwayBrowser/#/R-SSC-5654651 Activated FGFR4 binds FRS3 IEA Sus scrofa A0A287AFX3 R-SSC-5654653 https://reactome.org/PathwayBrowser/#/R-SSC-5654653 Activated FGFR4 phosphorylates FRS3 IEA Sus scrofa A0A287AFX3 R-SSC-5654655 https://reactome.org/PathwayBrowser/#/R-SSC-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Sus scrofa A0A287AFX3 R-SSC-5654658 https://reactome.org/PathwayBrowser/#/R-SSC-5654658 Activated FGFR4:p-FRS bind to PPTN11 IEA Sus scrofa A0A287AFX3 R-SSC-5654659 https://reactome.org/PathwayBrowser/#/R-SSC-5654659 Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Sus scrofa A0A287AFX3 R-SSC-5654662 https://reactome.org/PathwayBrowser/#/R-SSC-5654662 Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Sus scrofa A0A287AFX3 R-SSC-5654663 https://reactome.org/PathwayBrowser/#/R-SSC-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A287AFX3 R-SSC-5654664 https://reactome.org/PathwayBrowser/#/R-SSC-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Sus scrofa A0A287AFX3 R-SSC-5654667 https://reactome.org/PathwayBrowser/#/R-SSC-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Sus scrofa A0A287AFX3 R-SSC-5654669 https://reactome.org/PathwayBrowser/#/R-SSC-5654669 Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA IEA Sus scrofa A0A287AFX3 R-SSC-5654672 https://reactome.org/PathwayBrowser/#/R-SSC-5654672 CBL ubiquitinates FRS2 and FGFR1 IEA Sus scrofa A0A287AFX3 R-SSC-5654673 https://reactome.org/PathwayBrowser/#/R-SSC-5654673 p-CBL:GRB2 binds p-FRS2:activated FGFR1 IEA Sus scrofa A0A287AFX3 R-SSC-5654684 https://reactome.org/PathwayBrowser/#/R-SSC-5654684 CBL ubiquitinates FRS2 and FGFR4 IEA Sus scrofa A0A287AFX3 R-SSC-5654690 https://reactome.org/PathwayBrowser/#/R-SSC-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AFX3 R-SSC-5654692 https://reactome.org/PathwayBrowser/#/R-SSC-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AFX3 R-SSC-5654714 https://reactome.org/PathwayBrowser/#/R-SSC-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AFX3 R-SSC-5654717 https://reactome.org/PathwayBrowser/#/R-SSC-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AFX3 R-SSC-5654734 https://reactome.org/PathwayBrowser/#/R-SSC-5654734 p-CBL:GRB2 binds p-FRS2:activated FGFR4 IEA Sus scrofa A0A287AFX3 R-SSC-5656064 https://reactome.org/PathwayBrowser/#/R-SSC-5656064 Activated FGFR1 binds FLRT1,2,3 IEA Sus scrofa A0A287AFX3 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287AFX3 R-SSC-8941613 https://reactome.org/PathwayBrowser/#/R-SSC-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Sus scrofa A0A287AFX3 R-SSC-8941623 https://reactome.org/PathwayBrowser/#/R-SSC-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Sus scrofa A0A287AFZ0 R-SSC-111439 https://reactome.org/PathwayBrowser/#/R-SSC-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Sus scrofa A0A287AFZ0 R-SSC-158441 https://reactome.org/PathwayBrowser/#/R-SSC-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Sus scrofa A0A287AFZ0 R-SSC-158447 https://reactome.org/PathwayBrowser/#/R-SSC-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Sus scrofa A0A287AFZ0 R-SSC-158481 https://reactome.org/PathwayBrowser/#/R-SSC-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Sus scrofa A0A287AFZ0 R-SSC-158484 https://reactome.org/PathwayBrowser/#/R-SSC-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Sus scrofa A0A287AFZ0 R-SSC-159046 https://reactome.org/PathwayBrowser/#/R-SSC-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Sus scrofa A0A287AFZ0 R-SSC-159050 https://reactome.org/PathwayBrowser/#/R-SSC-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Sus scrofa A0A287AFZ0 R-SSC-191830 https://reactome.org/PathwayBrowser/#/R-SSC-191830 snRNP nuclear import and release IEA Sus scrofa A0A287AFZ0 R-SSC-2990880 https://reactome.org/PathwayBrowser/#/R-SSC-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Sus scrofa A0A287AFZ0 R-SSC-2990882 https://reactome.org/PathwayBrowser/#/R-SSC-2990882 CDK1 phosphorylates NUP98 IEA Sus scrofa A0A287AFZ0 R-SSC-3000348 https://reactome.org/PathwayBrowser/#/R-SSC-3000348 RANBP2 SUMOylates SP100 with SUMO2 IEA Sus scrofa A0A287AFZ0 R-SSC-3000399 https://reactome.org/PathwayBrowser/#/R-SSC-3000399 RANBP2 SUMOylates SP100 with SUMO1 IEA Sus scrofa A0A287AFZ0 R-SSC-3000411 https://reactome.org/PathwayBrowser/#/R-SSC-3000411 RANBP2 SUMOylates PML with SUMO2 IEA Sus scrofa A0A287AFZ0 R-SSC-4551649 https://reactome.org/PathwayBrowser/#/R-SSC-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Sus scrofa A0A287AFZ0 R-SSC-4551679 https://reactome.org/PathwayBrowser/#/R-SSC-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Sus scrofa A0A287AFZ0 R-SSC-4570493 https://reactome.org/PathwayBrowser/#/R-SSC-4570493 RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 IEA Sus scrofa A0A287AFZ0 R-SSC-4615872 https://reactome.org/PathwayBrowser/#/R-SSC-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Sus scrofa A0A287AFZ0 R-SSC-4615987 https://reactome.org/PathwayBrowser/#/R-SSC-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Sus scrofa A0A287AFZ0 R-SSC-4655355 https://reactome.org/PathwayBrowser/#/R-SSC-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Sus scrofa A0A287AFZ0 R-SSC-5228508 https://reactome.org/PathwayBrowser/#/R-SSC-5228508 RANBP2 SUMOylates PML with SUMO1 IEA Sus scrofa A0A287AFZ0 R-SSC-5228523 https://reactome.org/PathwayBrowser/#/R-SSC-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Sus scrofa A0A287AFZ0 R-SSC-5252041 https://reactome.org/PathwayBrowser/#/R-SSC-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Sus scrofa A0A287AFZ0 R-SSC-5578744 https://reactome.org/PathwayBrowser/#/R-SSC-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Sus scrofa A0A287AFZ0 R-SSC-75097 https://reactome.org/PathwayBrowser/#/R-SSC-75097 Transport of the export-competent mRNP complex through the NPC IEA Sus scrofa A0A287AFZ0 R-SSC-75098 https://reactome.org/PathwayBrowser/#/R-SSC-75098 mRNP complex dissociates from cytosolic face of NPC IEA Sus scrofa A0A287AFZ0 R-SSC-77587 https://reactome.org/PathwayBrowser/#/R-SSC-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Sus scrofa A0A287AFZ0 R-SSC-77594 https://reactome.org/PathwayBrowser/#/R-SSC-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Sus scrofa A0A287AG06 R-SSC-1855221 https://reactome.org/PathwayBrowser/#/R-SSC-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Sus scrofa A0A287AG10 R-SSC-3295579 https://reactome.org/PathwayBrowser/#/R-SSC-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Sus scrofa A0A287AG10 R-SSC-5218891 https://reactome.org/PathwayBrowser/#/R-SSC-5218891 RIPK1:RIPK3 oligomer binds MLKL IEA Sus scrofa A0A287AG10 R-SSC-5218906 https://reactome.org/PathwayBrowser/#/R-SSC-5218906 RIPK3 phosphorylates MLKL IEA Sus scrofa A0A287AG10 R-SSC-5620975 https://reactome.org/PathwayBrowser/#/R-SSC-5620975 MLKL binds PIPs IEA Sus scrofa A0A287AG10 R-SSC-9687625 https://reactome.org/PathwayBrowser/#/R-SSC-9687625 ATP binds MLKL IEA Sus scrofa A0A287AG10 R-SSC-9687638 https://reactome.org/PathwayBrowser/#/R-SSC-9687638 MLKL binds IP4, IP5 and IP6 IEA Sus scrofa A0A287AG10 R-SSC-9688456 https://reactome.org/PathwayBrowser/#/R-SSC-9688456 MLKL binds FLOT1, FLOT2 IEA Sus scrofa A0A287AG10 R-SSC-9688832 https://reactome.org/PathwayBrowser/#/R-SSC-9688832 MLKL binds PDCD6IP and SDCBP IEA Sus scrofa A0A287AG10 R-SSC-9698844 https://reactome.org/PathwayBrowser/#/R-SSC-9698844 MLKL binds HSP90:CDC37 IEA Sus scrofa A0A287AG10 R-SSC-9701055 https://reactome.org/PathwayBrowser/#/R-SSC-9701055 TRPA1 tetramer transports Ca2+ from extracellular region to cytosol IEA Sus scrofa A0A287AG10 R-SSC-9701141 https://reactome.org/PathwayBrowser/#/R-SSC-9701141 TRPV1 transports Ca2+ from extracellular region to cytosol IEA Sus scrofa A0A287AG10 R-SSC-9793444 https://reactome.org/PathwayBrowser/#/R-SSC-9793444 ITCH polyubiquitinates MLKL at K50 IEA Sus scrofa A0A287AG10 R-SSC-9793451 https://reactome.org/PathwayBrowser/#/R-SSC-9793451 MLKL binds ITCH IEA Sus scrofa A0A287AG11 R-SSC-5654510 https://reactome.org/PathwayBrowser/#/R-SSC-5654510 FGFRL1 binds SPRED1/2 IEA Sus scrofa A0A287AG11 R-SSC-5654511 https://reactome.org/PathwayBrowser/#/R-SSC-5654511 FGFRL1 dimer binds FGFs IEA Sus scrofa A0A287AG13 R-SSC-171059 https://reactome.org/PathwayBrowser/#/R-SSC-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Sus scrofa A0A287AG13 R-SSC-171106 https://reactome.org/PathwayBrowser/#/R-SSC-171106 LDLR:LDL complex => LDLR + LDL IEA Sus scrofa A0A287AG13 R-SSC-171122 https://reactome.org/PathwayBrowser/#/R-SSC-171122 LDL + LDLR => LDL:LDLR complex IEA Sus scrofa A0A287AG13 R-SSC-171141 https://reactome.org/PathwayBrowser/#/R-SSC-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Sus scrofa A0A287AG13 R-SSC-174587 https://reactome.org/PathwayBrowser/#/R-SSC-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Sus scrofa A0A287AG13 R-SSC-174657 https://reactome.org/PathwayBrowser/#/R-SSC-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Sus scrofa A0A287AG13 R-SSC-174660 https://reactome.org/PathwayBrowser/#/R-SSC-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Sus scrofa A0A287AG13 R-SSC-174690 https://reactome.org/PathwayBrowser/#/R-SSC-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Sus scrofa A0A287AG13 R-SSC-174706 https://reactome.org/PathwayBrowser/#/R-SSC-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Sus scrofa A0A287AG13 R-SSC-174731 https://reactome.org/PathwayBrowser/#/R-SSC-174731 Degradation of newly synthesized ApoB-48 IEA Sus scrofa A0A287AG13 R-SSC-174739 https://reactome.org/PathwayBrowser/#/R-SSC-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Sus scrofa A0A287AG13 R-SSC-174741 https://reactome.org/PathwayBrowser/#/R-SSC-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Sus scrofa A0A287AG13 R-SSC-174757 https://reactome.org/PathwayBrowser/#/R-SSC-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Sus scrofa A0A287AG13 R-SSC-174786 https://reactome.org/PathwayBrowser/#/R-SSC-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex IEA Sus scrofa A0A287AG13 R-SSC-203130 https://reactome.org/PathwayBrowser/#/R-SSC-203130 OLR1 binds to oxidized LDL IEA Sus scrofa A0A287AG13 R-SSC-2187332 https://reactome.org/PathwayBrowser/#/R-SSC-2187332 Cytosolic CMs translocate to extracellular region IEA Sus scrofa A0A287AG13 R-SSC-2197646 https://reactome.org/PathwayBrowser/#/R-SSC-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Sus scrofa A0A287AG13 R-SSC-2197770 https://reactome.org/PathwayBrowser/#/R-SSC-2197770 STAB1 (FEEL-1) binds ligands IEA Sus scrofa A0A287AG13 R-SSC-2203479 https://reactome.org/PathwayBrowser/#/R-SSC-2203479 STAB2 (FEEL-2) binds ligands IEA Sus scrofa A0A287AG13 R-SSC-2247511 https://reactome.org/PathwayBrowser/#/R-SSC-2247511 STAB2:ligand is endocytosed IEA Sus scrofa A0A287AG13 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa A0A287AG13 R-SSC-2247513 https://reactome.org/PathwayBrowser/#/R-SSC-2247513 STAB1:ligand is endocytosed IEA Sus scrofa A0A287AG13 R-SSC-2395764 https://reactome.org/PathwayBrowser/#/R-SSC-2395764 atREs binds to nascent CM IEA Sus scrofa A0A287AG13 R-SSC-2395768 https://reactome.org/PathwayBrowser/#/R-SSC-2395768 LPL hydrolyses TGs from mature CMs IEA Sus scrofa A0A287AG13 R-SSC-2395784 https://reactome.org/PathwayBrowser/#/R-SSC-2395784 Nascent CMs transform into mature CMs IEA Sus scrofa A0A287AG13 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa A0A287AG13 R-SSC-2423785 https://reactome.org/PathwayBrowser/#/R-SSC-2423785 CR:atREs binds apoE and HSPG IEA Sus scrofa A0A287AG13 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa A0A287AG13 R-SSC-2512800 https://reactome.org/PathwayBrowser/#/R-SSC-2512800 SCARB1:ligand is endocytosed IEA Sus scrofa A0A287AG13 R-SSC-432121 https://reactome.org/PathwayBrowser/#/R-SSC-432121 LDL binds to LRP8 IEA Sus scrofa A0A287AG13 R-SSC-432129 https://reactome.org/PathwayBrowser/#/R-SSC-432129 FGR binds and phosphorylates LRP8 IEA Sus scrofa A0A287AG13 R-SSC-435244 https://reactome.org/PathwayBrowser/#/R-SSC-435244 PECAM1 is phosphorylated IEA Sus scrofa A0A287AG13 R-SSC-8863471 https://reactome.org/PathwayBrowser/#/R-SSC-8863471 LDLR is bound by DAB2 and ARH IEA Sus scrofa A0A287AG13 R-SSC-8865667 https://reactome.org/PathwayBrowser/#/R-SSC-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Sus scrofa A0A287AG13 R-SSC-8866304 https://reactome.org/PathwayBrowser/#/R-SSC-8866304 pre-VLDL binds lipids to form VLDL IEA Sus scrofa A0A287AG13 R-SSC-8866308 https://reactome.org/PathwayBrowser/#/R-SSC-8866308 pre-VLDL translocates from RER membrane to SER lumen IEA Sus scrofa A0A287AG13 R-SSC-8866327 https://reactome.org/PathwayBrowser/#/R-SSC-8866327 VLDL translocates from SER lumen to extracellular region IEA Sus scrofa A0A287AG13 R-SSC-8866329 https://reactome.org/PathwayBrowser/#/R-SSC-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Sus scrofa A0A287AG13 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A287AG13 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A287AG13 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A287AG13 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A287AG13 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A287AG13 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287AG13 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287AG13 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287AG13 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287AG13 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287AG13 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287AG13 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287AG13 R-SSC-8869667 https://reactome.org/PathwayBrowser/#/R-SSC-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Sus scrofa A0A287AG13 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287AG13 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287AG13 R-SSC-8876366 https://reactome.org/PathwayBrowser/#/R-SSC-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Sus scrofa A0A287AG13 R-SSC-8948034 https://reactome.org/PathwayBrowser/#/R-SSC-8948034 FGR binds LDL:LRP8 IEA Sus scrofa A0A287AG13 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A287AG13 R-SSC-9707586 https://reactome.org/PathwayBrowser/#/R-SSC-9707586 FeHM oxidises LDL,HDL IEA Sus scrofa A0A287AG20 R-SSC-4088024 https://reactome.org/PathwayBrowser/#/R-SSC-4088024 CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 IEA Sus scrofa A0A287AG20 R-SSC-4088130 https://reactome.org/PathwayBrowser/#/R-SSC-4088130 PLK1 binds FOXM1 IEA Sus scrofa A0A287AG20 R-SSC-4088134 https://reactome.org/PathwayBrowser/#/R-SSC-4088134 PLK1 phosphorylates FOXM1 IEA Sus scrofa A0A287AG20 R-SSC-4088141 https://reactome.org/PathwayBrowser/#/R-SSC-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Sus scrofa A0A287AG39 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A287AG39 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287AG39 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A287AG39 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A287AG48 R-SSC-6805546 https://reactome.org/PathwayBrowser/#/R-SSC-6805546 Keratin type I binds keratin type II IEA Sus scrofa A0A287AG48 R-SSC-6805573 https://reactome.org/PathwayBrowser/#/R-SSC-6805573 Keratin type I/type II heterodimers form tetramers IEA Sus scrofa A0A287AG48 R-SSC-6806610 https://reactome.org/PathwayBrowser/#/R-SSC-6806610 Keratin filament formation IEA Sus scrofa A0A287AG48 R-SSC-6806613 https://reactome.org/PathwayBrowser/#/R-SSC-6806613 Keratin tetramers bind to form unit length filaments IEA Sus scrofa A0A287AG48 R-SSC-6806629 https://reactome.org/PathwayBrowser/#/R-SSC-6806629 Formation of tonofilament bundles IEA Sus scrofa A0A287AG48 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A287AG48 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287AG48 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A287AG48 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A287AG55 R-SSC-8854759 https://reactome.org/PathwayBrowser/#/R-SSC-8854759 TBC1D14 binds RAB11 and ULK1 IEA Sus scrofa A0A287AG72 R-SSC-9018787 https://reactome.org/PathwayBrowser/#/R-SSC-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Sus scrofa A0A287AG87 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287AG87 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287AG87 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287AGA4 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A287AGA4 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287AGA4 R-SSC-70467 https://reactome.org/PathwayBrowser/#/R-SSC-70467 PFK tetramer phosphorylates Fru(6)P IEA Sus scrofa A0A287AGB0 R-SSC-5578783 https://reactome.org/PathwayBrowser/#/R-SSC-5578783 CORIN(802-1042) hydrolyses NPPA to form NPPA(124-151) IEA Sus scrofa A0A287AGC8 R-SSC-173481 https://reactome.org/PathwayBrowser/#/R-SSC-173481 SKI/SKIL binds SMAD complex, suppressing TGF-beta signaling IEA Sus scrofa A0A287AGC8 R-SSC-201423 https://reactome.org/PathwayBrowser/#/R-SSC-201423 SKI complexes with the Smad complex, suppressing BMP2 signalling IEA Sus scrofa A0A287AGC8 R-SSC-2186767 https://reactome.org/PathwayBrowser/#/R-SSC-2186767 Degradation of ubiquitinated SKI/SKIL IEA Sus scrofa A0A287AGE8 R-SSC-71541 https://reactome.org/PathwayBrowser/#/R-SSC-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Sus scrofa A0A287AGE8 R-SSC-71588 https://reactome.org/PathwayBrowser/#/R-SSC-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Sus scrofa A0A287AGE9 R-SSC-2584246 https://reactome.org/PathwayBrowser/#/R-SSC-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Sus scrofa A0A287AGF2 R-SSC-1606839 https://reactome.org/PathwayBrowser/#/R-SSC-1606839 ARSC hydrolyzes steroid sulfates IEA Sus scrofa A0A287AGF2 R-SSC-1614362 https://reactome.org/PathwayBrowser/#/R-SSC-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Sus scrofa A0A287AGF3 R-SSC-8982012 https://reactome.org/PathwayBrowser/#/R-SSC-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Sus scrofa A0A287AGF3 R-SSC-8982019 https://reactome.org/PathwayBrowser/#/R-SSC-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Sus scrofa A0A287AGF3 R-SSC-8982020 https://reactome.org/PathwayBrowser/#/R-SSC-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Sus scrofa A0A287AGF4 R-SSC-9818574 https://reactome.org/PathwayBrowser/#/R-SSC-9818574 TASP1 cleaves KMT2A IEA Sus scrofa A0A287AGF6 R-SSC-425577 https://reactome.org/PathwayBrowser/#/R-SSC-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Sus scrofa A0A287AGF9 R-SSC-4570467 https://reactome.org/PathwayBrowser/#/R-SSC-4570467 SUMOylation of NOP58 with SUMO1 IEA Sus scrofa A0A287AGF9 R-SSC-4570489 https://reactome.org/PathwayBrowser/#/R-SSC-4570489 SUMOylation of NOP58 with SUMO2 IEA Sus scrofa A0A287AGF9 R-SSC-6791221 https://reactome.org/PathwayBrowser/#/R-SSC-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA IEA Sus scrofa A0A287AGF9 R-SSC-6791222 https://reactome.org/PathwayBrowser/#/R-SSC-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Sus scrofa A0A287AGF9 R-SSC-6791227 https://reactome.org/PathwayBrowser/#/R-SSC-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Sus scrofa A0A287AGH0 R-SSC-156826 https://reactome.org/PathwayBrowser/#/R-SSC-156826 Dissociation of L13a from the 60s ribosomal subunit IEA Sus scrofa A0A287AGH0 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A287AGH0 R-SSC-6791218 https://reactome.org/PathwayBrowser/#/R-SSC-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Sus scrofa A0A287AGH0 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A287AGH0 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A287AGH0 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A287AGH0 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A287AGH0 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A287AGH0 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A287AGH0 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A287AGH0 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A287AGI3 R-SSC-159101 https://reactome.org/PathwayBrowser/#/R-SSC-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Sus scrofa A0A287AGI3 R-SSC-72180 https://reactome.org/PathwayBrowser/#/R-SSC-72180 Cleavage of mRNA at the 3'-end IEA Sus scrofa A0A287AGI3 R-SSC-72185 https://reactome.org/PathwayBrowser/#/R-SSC-72185 mRNA polyadenylation IEA Sus scrofa A0A287AGI3 R-SSC-8849157 https://reactome.org/PathwayBrowser/#/R-SSC-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Sus scrofa A0A287AGI3 R-SSC-9770119 https://reactome.org/PathwayBrowser/#/R-SSC-9770119 Formation of the Spliceosomal E complex IEA Sus scrofa A0A287AGI3 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287AGJ1 R-SSC-9914364 https://reactome.org/PathwayBrowser/#/R-SSC-9914364 POLG in the replisome polymerizes the H strand IEA Sus scrofa A0A287AGJ1 R-SSC-9914404 https://reactome.org/PathwayBrowser/#/R-SSC-9914404 POLRMT and POLG bind the mitochondrial L strand replication origin (OriL) IEA Sus scrofa A0A287AGJ1 R-SSC-9914409 https://reactome.org/PathwayBrowser/#/R-SSC-9914409 POLRMT polymerizes RNA primer for mitochondrial L strand replication IEA Sus scrofa A0A287AGJ1 R-SSC-9914438 https://reactome.org/PathwayBrowser/#/R-SSC-9914438 TWNK (PEO1) unwinds double-stranded mitochondrial DNA at the replication fork IEA Sus scrofa A0A287AGJ1 R-SSC-9914478 https://reactome.org/PathwayBrowser/#/R-SSC-9914478 SSBP1 binds the displaced parental H strand IEA Sus scrofa A0A287AGJ1 R-SSC-9914498 https://reactome.org/PathwayBrowser/#/R-SSC-9914498 POLG in the replisome polymerizes the L strand IEA Sus scrofa A0A287AGL1 R-SSC-3640872 https://reactome.org/PathwayBrowser/#/R-SSC-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Sus scrofa A0A287AGM8 R-SSC-6798739 https://reactome.org/PathwayBrowser/#/R-SSC-6798739 Exocytosis of azurophil granule membrane proteins IEA Sus scrofa A0A287AGN3 R-SSC-5251942 https://reactome.org/PathwayBrowser/#/R-SSC-5251942 Hikeshi binds HSP70s:ATP IEA Sus scrofa A0A287AGN3 R-SSC-5251955 https://reactome.org/PathwayBrowser/#/R-SSC-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Sus scrofa A0A287AGN3 R-SSC-5251959 https://reactome.org/PathwayBrowser/#/R-SSC-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Sus scrofa A0A287AGN3 R-SSC-5252041 https://reactome.org/PathwayBrowser/#/R-SSC-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Sus scrofa A0A287AGN3 R-SSC-5252079 https://reactome.org/PathwayBrowser/#/R-SSC-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Sus scrofa A0A287AGQ6 R-SSC-3247837 https://reactome.org/PathwayBrowser/#/R-SSC-3247837 WNT ligands traffic to the Golgi IEA Sus scrofa A0A287AGQ6 R-SSC-3247840 https://reactome.org/PathwayBrowser/#/R-SSC-3247840 WLS binds WNT ligands in the Golgi IEA Sus scrofa A0A287AGQ6 R-SSC-3247843 https://reactome.org/PathwayBrowser/#/R-SSC-3247843 secretion of WNT ligands IEA Sus scrofa A0A287AGQ6 R-SSC-3247844 https://reactome.org/PathwayBrowser/#/R-SSC-3247844 WNT ligands traffic to the plasma membrane IEA Sus scrofa A0A287AGQ6 R-SSC-3781941 https://reactome.org/PathwayBrowser/#/R-SSC-3781941 WNTs are secreted in exosomes IEA Sus scrofa A0A287AGQ6 R-SSC-3781943 https://reactome.org/PathwayBrowser/#/R-SSC-3781943 WLS:WNT complex is internalized for maturation into exosomes IEA Sus scrofa A0A287AGR5 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287AGS3 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A287AGS3 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa A0A287AGS6 R-SSC-427570 https://reactome.org/PathwayBrowser/#/R-SSC-427570 Group 3 - Selective Cl- transport IEA Sus scrofa A0A287AGU4 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AGV4 R-SSC-3222006 https://reactome.org/PathwayBrowser/#/R-SSC-3222006 STK11 (LKB1) phosphorylates NUAK1 IEA Sus scrofa A0A287AGV4 R-SSC-3222020 https://reactome.org/PathwayBrowser/#/R-SSC-3222020 NUAK1 phosphorylates TP53 IEA Sus scrofa A0A287AGV4 R-SSC-6805035 https://reactome.org/PathwayBrowser/#/R-SSC-6805035 TP53 binds STK11 and NUAK1 IEA Sus scrofa A0A287AGW3 R-SSC-507719 https://reactome.org/PathwayBrowser/#/R-SSC-507719 p62:MEKK3 binds to TRAF6 IEA Sus scrofa A0A287AGY4 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287AGZ2 R-SSC-114261 https://reactome.org/PathwayBrowser/#/R-SSC-114261 Cleavage of Procaspase-7 by the apoptosome IEA Sus scrofa A0A287AGZ2 R-SSC-114354 https://reactome.org/PathwayBrowser/#/R-SSC-114354 SMAC binds XIAP:Caspase-7 IEA Sus scrofa A0A287AGZ2 R-SSC-114392 https://reactome.org/PathwayBrowser/#/R-SSC-114392 Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 IEA Sus scrofa A0A287AGZ2 R-SSC-201628 https://reactome.org/PathwayBrowser/#/R-SSC-201628 Caspase-mediated cleavage of vimentin at DSVD (85) IEA Sus scrofa A0A287AGZ2 R-SSC-201639 https://reactome.org/PathwayBrowser/#/R-SSC-201639 Caspase-mediated cleavage of GAS2 IEA Sus scrofa A0A287AGZ2 R-SSC-351901 https://reactome.org/PathwayBrowser/#/R-SSC-351901 Caspase-mediated cleavage of MST3 IEA Sus scrofa A0A287AGZ2 R-SSC-351936 https://reactome.org/PathwayBrowser/#/R-SSC-351936 Caspase-mediated cleavage of claspin IEA Sus scrofa A0A287AGZ2 R-SSC-9029680 https://reactome.org/PathwayBrowser/#/R-SSC-9029680 Caspase-7 translocates to the nucleus IEA Sus scrofa A0A287AGZ2 R-SSC-9627107 https://reactome.org/PathwayBrowser/#/R-SSC-9627107 XIAP binds CASP7 IEA Sus scrofa A0A287AGZ7 R-SSC-201510 https://reactome.org/PathwayBrowser/#/R-SSC-201510 PI3K synthesizes PIP3 downstream of ALK IEA Sus scrofa A0A287AGZ7 R-SSC-201515 https://reactome.org/PathwayBrowser/#/R-SSC-201515 Active ALK recruits PI3K IEA Sus scrofa A0A287AGZ7 R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa A0A287AGZ7 R-SSC-9700149 https://reactome.org/PathwayBrowser/#/R-SSC-9700149 Active ALK binds PLCG1 IEA Sus scrofa A0A287AGZ7 R-SSC-9700154 https://reactome.org/PathwayBrowser/#/R-SSC-9700154 Active ALK binds SHC1 IEA Sus scrofa A0A287AGZ7 R-SSC-9700156 https://reactome.org/PathwayBrowser/#/R-SSC-9700156 Active ALK dimer binds IRS1 IEA Sus scrofa A0A287AGZ7 R-SSC-9700168 https://reactome.org/PathwayBrowser/#/R-SSC-9700168 Active ALK phosphorylates IRS1 IEA Sus scrofa A0A287AGZ7 R-SSC-9700171 https://reactome.org/PathwayBrowser/#/R-SSC-9700171 Active ALK phosphorylates PLCG1 IEA Sus scrofa A0A287AGZ7 R-SSC-9700175 https://reactome.org/PathwayBrowser/#/R-SSC-9700175 Active ALK phosphorylates SHC1 IEA Sus scrofa A0A287AGZ7 R-SSC-9700662 https://reactome.org/PathwayBrowser/#/R-SSC-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Sus scrofa A0A287AGZ7 R-SSC-9701485 https://reactome.org/PathwayBrowser/#/R-SSC-9701485 Active ALK binds JAK3 IEA Sus scrofa A0A287AGZ7 R-SSC-9701488 https://reactome.org/PathwayBrowser/#/R-SSC-9701488 Active ALK phosphorylates JAK3 IEA Sus scrofa A0A287AGZ7 R-SSC-9701507 https://reactome.org/PathwayBrowser/#/R-SSC-9701507 PTPN6 dephosphorylates JAK3 IEA Sus scrofa A0A287AGZ7 R-SSC-9701524 https://reactome.org/PathwayBrowser/#/R-SSC-9701524 STAT3 is phosphorylated downstream of active ALK IEA Sus scrofa A0A287AGZ7 R-SSC-9842656 https://reactome.org/PathwayBrowser/#/R-SSC-9842656 ALK binds ALKAL ligand IEA Sus scrofa A0A287AH24 R-SSC-5620975 https://reactome.org/PathwayBrowser/#/R-SSC-5620975 MLKL binds PIPs IEA Sus scrofa A0A287AH24 R-SSC-9688832 https://reactome.org/PathwayBrowser/#/R-SSC-9688832 MLKL binds PDCD6IP and SDCBP IEA Sus scrofa A0A287AH26 R-SSC-109639 https://reactome.org/PathwayBrowser/#/R-SSC-109639 Formation of the closed pre-initiation complex IEA Sus scrofa A0A287AH26 R-SSC-111264 https://reactome.org/PathwayBrowser/#/R-SSC-111264 Addition of nucleotides between position +11 and +30 IEA Sus scrofa A0A287AH26 R-SSC-112379 https://reactome.org/PathwayBrowser/#/R-SSC-112379 Recruitment of elongation factors to form elongation complex IEA Sus scrofa A0A287AH26 R-SSC-112383 https://reactome.org/PathwayBrowser/#/R-SSC-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Sus scrofa A0A287AH26 R-SSC-112385 https://reactome.org/PathwayBrowser/#/R-SSC-112385 Addition of nucleotides leads to transcript elongation IEA Sus scrofa A0A287AH26 R-SSC-113430 https://reactome.org/PathwayBrowser/#/R-SSC-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Sus scrofa A0A287AH26 R-SSC-5689317 https://reactome.org/PathwayBrowser/#/R-SSC-5689317 Formation of the pre-incision complex in GG-NER IEA Sus scrofa A0A287AH26 R-SSC-5689861 https://reactome.org/PathwayBrowser/#/R-SSC-5689861 Recruitment of XPA and release of CAK IEA Sus scrofa A0A287AH26 R-SSC-5690213 https://reactome.org/PathwayBrowser/#/R-SSC-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Sus scrofa A0A287AH26 R-SSC-5690988 https://reactome.org/PathwayBrowser/#/R-SSC-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Sus scrofa A0A287AH26 R-SSC-5690990 https://reactome.org/PathwayBrowser/#/R-SSC-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Sus scrofa A0A287AH26 R-SSC-5690991 https://reactome.org/PathwayBrowser/#/R-SSC-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER IEA Sus scrofa A0A287AH26 R-SSC-5690996 https://reactome.org/PathwayBrowser/#/R-SSC-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Sus scrofa A0A287AH26 R-SSC-5691000 https://reactome.org/PathwayBrowser/#/R-SSC-5691000 TFIIH binds GG-NER site to form a verification complex IEA Sus scrofa A0A287AH26 R-SSC-5696670 https://reactome.org/PathwayBrowser/#/R-SSC-5696670 CHD1L is recruited to GG-NER site IEA Sus scrofa A0A287AH26 R-SSC-6781818 https://reactome.org/PathwayBrowser/#/R-SSC-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Sus scrofa A0A287AH26 R-SSC-6781824 https://reactome.org/PathwayBrowser/#/R-SSC-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Sus scrofa A0A287AH26 R-SSC-6781833 https://reactome.org/PathwayBrowser/#/R-SSC-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Sus scrofa A0A287AH26 R-SSC-6781867 https://reactome.org/PathwayBrowser/#/R-SSC-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Sus scrofa A0A287AH26 R-SSC-6782004 https://reactome.org/PathwayBrowser/#/R-SSC-6782004 Assembly of the pre-incision complex in TC-NER IEA Sus scrofa A0A287AH26 R-SSC-6782069 https://reactome.org/PathwayBrowser/#/R-SSC-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Sus scrofa A0A287AH26 R-SSC-6782131 https://reactome.org/PathwayBrowser/#/R-SSC-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa A0A287AH26 R-SSC-6782138 https://reactome.org/PathwayBrowser/#/R-SSC-6782138 ERCC5 and RPA bind TC-NER site IEA Sus scrofa A0A287AH26 R-SSC-6782141 https://reactome.org/PathwayBrowser/#/R-SSC-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Sus scrofa A0A287AH26 R-SSC-6782204 https://reactome.org/PathwayBrowser/#/R-SSC-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Sus scrofa A0A287AH26 R-SSC-6782208 https://reactome.org/PathwayBrowser/#/R-SSC-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Sus scrofa A0A287AH26 R-SSC-6782211 https://reactome.org/PathwayBrowser/#/R-SSC-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Sus scrofa A0A287AH26 R-SSC-6782224 https://reactome.org/PathwayBrowser/#/R-SSC-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Sus scrofa A0A287AH26 R-SSC-6782227 https://reactome.org/PathwayBrowser/#/R-SSC-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Sus scrofa A0A287AH26 R-SSC-6790454 https://reactome.org/PathwayBrowser/#/R-SSC-6790454 SUMOylation of XPC IEA Sus scrofa A0A287AH26 R-SSC-6797606 https://reactome.org/PathwayBrowser/#/R-SSC-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Sus scrofa A0A287AH26 R-SSC-6797616 https://reactome.org/PathwayBrowser/#/R-SSC-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Sus scrofa A0A287AH26 R-SSC-73758 https://reactome.org/PathwayBrowser/#/R-SSC-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Sus scrofa A0A287AH26 R-SSC-73769 https://reactome.org/PathwayBrowser/#/R-SSC-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Sus scrofa A0A287AH26 R-SSC-73946 https://reactome.org/PathwayBrowser/#/R-SSC-73946 Abortive initiation after formation of the first phosphodiester bond IEA Sus scrofa A0A287AH26 R-SSC-74986 https://reactome.org/PathwayBrowser/#/R-SSC-74986 Elongation of pre-rRNA transcript IEA Sus scrofa A0A287AH26 R-SSC-74993 https://reactome.org/PathwayBrowser/#/R-SSC-74993 PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box IEA Sus scrofa A0A287AH26 R-SSC-75850 https://reactome.org/PathwayBrowser/#/R-SSC-75850 Addition of the third nucleotide on the nascent transcript IEA Sus scrofa A0A287AH26 R-SSC-75856 https://reactome.org/PathwayBrowser/#/R-SSC-75856 Abortive Initiation Before Second Transition IEA Sus scrofa A0A287AH26 R-SSC-75861 https://reactome.org/PathwayBrowser/#/R-SSC-75861 NTP Binds Active Site of RNA Polymerase II IEA Sus scrofa A0A287AH26 R-SSC-75862 https://reactome.org/PathwayBrowser/#/R-SSC-75862 Fall Back to Closed Pre-initiation Complex IEA Sus scrofa A0A287AH26 R-SSC-75864 https://reactome.org/PathwayBrowser/#/R-SSC-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Sus scrofa A0A287AH26 R-SSC-75866 https://reactome.org/PathwayBrowser/#/R-SSC-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Sus scrofa A0A287AH26 R-SSC-75869 https://reactome.org/PathwayBrowser/#/R-SSC-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Sus scrofa A0A287AH26 R-SSC-75873 https://reactome.org/PathwayBrowser/#/R-SSC-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Sus scrofa A0A287AH26 R-SSC-75891 https://reactome.org/PathwayBrowser/#/R-SSC-75891 Abortive Initiation After Second Transition IEA Sus scrofa A0A287AH26 R-SSC-75949 https://reactome.org/PathwayBrowser/#/R-SSC-75949 RNA Polymerase II Promoter Opening: First Transition IEA Sus scrofa A0A287AH26 R-SSC-76576 https://reactome.org/PathwayBrowser/#/R-SSC-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Sus scrofa A0A287AH26 R-SSC-77068 https://reactome.org/PathwayBrowser/#/R-SSC-77068 Activation of GT IEA Sus scrofa A0A287AH26 R-SSC-77069 https://reactome.org/PathwayBrowser/#/R-SSC-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Sus scrofa A0A287AH26 R-SSC-77071 https://reactome.org/PathwayBrowser/#/R-SSC-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Sus scrofa A0A287AH26 R-SSC-77073 https://reactome.org/PathwayBrowser/#/R-SSC-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Sus scrofa A0A287AH26 R-SSC-77077 https://reactome.org/PathwayBrowser/#/R-SSC-77077 Capping complex formation IEA Sus scrofa A0A287AH26 R-SSC-77078 https://reactome.org/PathwayBrowser/#/R-SSC-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Sus scrofa A0A287AH26 R-SSC-77081 https://reactome.org/PathwayBrowser/#/R-SSC-77081 Formation of the CE:GMP intermediate complex IEA Sus scrofa A0A287AH26 R-SSC-77083 https://reactome.org/PathwayBrowser/#/R-SSC-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Sus scrofa A0A287AH26 R-SSC-77085 https://reactome.org/PathwayBrowser/#/R-SSC-77085 Dissociation of transcript with 5'-GMP from GT IEA Sus scrofa A0A287AH26 R-SSC-77090 https://reactome.org/PathwayBrowser/#/R-SSC-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Sus scrofa A0A287AH26 R-SSC-9613494 https://reactome.org/PathwayBrowser/#/R-SSC-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Sus scrofa A0A287AH26 R-SSC-9613497 https://reactome.org/PathwayBrowser/#/R-SSC-9613497 Unwinding DNA for the nascent transcript IEA Sus scrofa A0A287AH26 R-SSC-9684118 https://reactome.org/PathwayBrowser/#/R-SSC-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa A0A287AH57 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AH57 R-SSC-983152 https://reactome.org/PathwayBrowser/#/R-SSC-983152 Transfer of ubiquitin from E1 to E2 IEA Sus scrofa A0A287AH57 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AH57 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AH60 R-SSC-6801242 https://reactome.org/PathwayBrowser/#/R-SSC-6801242 TRIAP1 binds PRELID1, PRELID3A IEA Sus scrofa A0A287AH60 R-SSC-6801250 https://reactome.org/PathwayBrowser/#/R-SSC-6801250 TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane IEA Sus scrofa A0A287AH62 R-SSC-8931648 https://reactome.org/PathwayBrowser/#/R-SSC-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 IEA Sus scrofa A0A287AH65 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa A0A287AH65 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa A0A287AH65 R-SSC-432946 https://reactome.org/PathwayBrowser/#/R-SSC-432946 PARVB/Affixin interacts with alpha PIX IEA Sus scrofa A0A287AH65 R-SSC-8964599 https://reactome.org/PathwayBrowser/#/R-SSC-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Sus scrofa A0A287AH65 R-SSC-8964604 https://reactome.org/PathwayBrowser/#/R-SSC-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Sus scrofa A0A287AH65 R-SSC-8964605 https://reactome.org/PathwayBrowser/#/R-SSC-8964605 PAK1:ARHGEF6 complex binds G-protein beta-gamma complex IEA Sus scrofa A0A287AH65 R-SSC-8964614 https://reactome.org/PathwayBrowser/#/R-SSC-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Sus scrofa A0A287AH65 R-SSC-8964619 https://reactome.org/PathwayBrowser/#/R-SSC-8964619 PAK1 binds ARHGEF6 IEA Sus scrofa A0A287AH65 R-SSC-8964634 https://reactome.org/PathwayBrowser/#/R-SSC-8964634 CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex IEA Sus scrofa A0A287AH65 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A287AH65 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa A0A287AH65 R-SSC-9018766 https://reactome.org/PathwayBrowser/#/R-SSC-9018766 RHOU binds effectors at the plasma membrane IEA Sus scrofa A0A287AH76 R-SSC-9933236 https://reactome.org/PathwayBrowser/#/R-SSC-9933236 SS18-containing ATPase complex binds SMARCC dimer:SMARCDs:BICRAs:BRD9 IEA Sus scrofa A0A287AH76 R-SSC-9933238 https://reactome.org/PathwayBrowser/#/R-SSC-9933238 SS18-containing ATPase complex binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1:DPF1,2,3 IEA Sus scrofa A0A287AH76 R-SSC-9934024 https://reactome.org/PathwayBrowser/#/R-SSC-9934024 SMARCA4, BCL11A,B-containing ATPase module binds SMARCC1:SMACC2 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1A:DPF2, PHF10 IEA Sus scrofa A0A287AH83 R-SSC-1504186 https://reactome.org/PathwayBrowser/#/R-SSC-1504186 DVL recruits GSK3beta:AXIN1 to the receptor complex IEA Sus scrofa A0A287AH83 R-SSC-201677 https://reactome.org/PathwayBrowser/#/R-SSC-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Sus scrofa A0A287AH83 R-SSC-201685 https://reactome.org/PathwayBrowser/#/R-SSC-201685 Beta-catenin is released from the destruction complex IEA Sus scrofa A0A287AH83 R-SSC-3858482 https://reactome.org/PathwayBrowser/#/R-SSC-3858482 DVL is recruited to the receptor IEA Sus scrofa A0A287AH83 R-SSC-5099886 https://reactome.org/PathwayBrowser/#/R-SSC-5099886 WNT5A binding to FZD promotes PRICKLE1 degradation IEA Sus scrofa A0A287AH84 R-SSC-9696266 https://reactome.org/PathwayBrowser/#/R-SSC-9696266 RND2 binds effectors IEA Sus scrofa A0A287AH84 R-SSC-9696268 https://reactome.org/PathwayBrowser/#/R-SSC-9696268 RND3 binds effectors IEA Sus scrofa A0A287AH84 R-SSC-9696271 https://reactome.org/PathwayBrowser/#/R-SSC-9696271 RND1 binds effectors IEA Sus scrofa A0A287AH87 R-SSC-5684864 https://reactome.org/PathwayBrowser/#/R-SSC-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Sus scrofa A0A287AH87 R-SSC-5685902 https://reactome.org/PathwayBrowser/#/R-SSC-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Sus scrofa A0A287AH92 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A287AH92 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A287AH92 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A287AH92 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A287AH92 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A287AH92 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A287AH92 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A287AH92 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A287AH92 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A287AH92 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287AH92 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A287AH92 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A287AH92 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287AH92 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A287AH92 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287AH92 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287AH92 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287AH92 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287AH92 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287AH92 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A287AH92 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A287AH94 R-SSC-9640167 https://reactome.org/PathwayBrowser/#/R-SSC-9640167 RRAGA,B exchanges GDP for GTP IEA Sus scrofa A0A287AHA8 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287AHA8 R-SSC-388560 https://reactome.org/PathwayBrowser/#/R-SSC-388560 EDNRA,EDNRB bind EDNs IEA Sus scrofa A0A287AHA8 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287AHA8 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287AHA8 R-SSC-8876868 https://reactome.org/PathwayBrowser/#/R-SSC-8876868 ECE1 cleaves EDN1(53-90) IEA Sus scrofa A0A287AHA8 R-SSC-8877620 https://reactome.org/PathwayBrowser/#/R-SSC-8877620 ECE2 cleaves EDN1(53-90) IEA Sus scrofa A0A287AHA8 R-SSC-9731924 https://reactome.org/PathwayBrowser/#/R-SSC-9731924 EDNRA binds EDNs IEA Sus scrofa A0A287AHB3 R-SSC-4641155 https://reactome.org/PathwayBrowser/#/R-SSC-4641155 DVL1 is bound by the HECT ubiquitin ligase HECW1 IEA Sus scrofa A0A287AHB3 R-SSC-4641159 https://reactome.org/PathwayBrowser/#/R-SSC-4641159 DVL1 is ubiquitinated by HECW1 IEA Sus scrofa A0A287AHB3 R-SSC-4641260 https://reactome.org/PathwayBrowser/#/R-SSC-4641260 Ubiquitinated DVL1 is degraded by the proteasome IEA Sus scrofa A0A287AHB4 R-SSC-210420 https://reactome.org/PathwayBrowser/#/R-SSC-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Sus scrofa A0A287AHC2 R-SSC-6799604 https://reactome.org/PathwayBrowser/#/R-SSC-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Sus scrofa A0A287AHC5 R-SSC-1013012 https://reactome.org/PathwayBrowser/#/R-SSC-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Sus scrofa A0A287AHC5 R-SSC-1013013 https://reactome.org/PathwayBrowser/#/R-SSC-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Sus scrofa A0A287AHC5 R-SSC-1013020 https://reactome.org/PathwayBrowser/#/R-SSC-1013020 Activation of GIRK/Kir3 Channels IEA Sus scrofa A0A287AHC5 R-SSC-112271 https://reactome.org/PathwayBrowser/#/R-SSC-112271 The receptor:G-protein complex dissociates IEA Sus scrofa A0A287AHC5 R-SSC-114552 https://reactome.org/PathwayBrowser/#/R-SSC-114552 Thrombin-activated PARs activate G12/13 IEA Sus scrofa A0A287AHC5 R-SSC-114558 https://reactome.org/PathwayBrowser/#/R-SSC-114558 Thrombin-activated PARs activate Gq IEA Sus scrofa A0A287AHC5 R-SSC-167408 https://reactome.org/PathwayBrowser/#/R-SSC-167408 The high affinity receptor complex binds to G-protein IEA Sus scrofa A0A287AHC5 R-SSC-167419 https://reactome.org/PathwayBrowser/#/R-SSC-167419 The receptor:G-protein complex releases GDP IEA Sus scrofa A0A287AHC5 R-SSC-167429 https://reactome.org/PathwayBrowser/#/R-SSC-167429 The receptor:G-protein complex binds GTP IEA Sus scrofa A0A287AHC5 R-SSC-167433 https://reactome.org/PathwayBrowser/#/R-SSC-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Sus scrofa A0A287AHC5 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa A0A287AHC5 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287AHC5 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287AHC5 R-SSC-381612 https://reactome.org/PathwayBrowser/#/R-SSC-381612 GLP1R binds GLP1 IEA Sus scrofa A0A287AHC5 R-SSC-392187 https://reactome.org/PathwayBrowser/#/R-SSC-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Sus scrofa A0A287AHC5 R-SSC-392195 https://reactome.org/PathwayBrowser/#/R-SSC-392195 Gi activation by P2Y purinoceptor 12 IEA Sus scrofa A0A287AHC5 R-SSC-392202 https://reactome.org/PathwayBrowser/#/R-SSC-392202 Dissociation of the P2Y purinoceptor 12:Gi complex IEA Sus scrofa A0A287AHC5 R-SSC-392295 https://reactome.org/PathwayBrowser/#/R-SSC-392295 Gbeta:gamma recruits PI3K gamma IEA Sus scrofa A0A287AHC5 R-SSC-392300 https://reactome.org/PathwayBrowser/#/R-SSC-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Sus scrofa A0A287AHC5 R-SSC-392870 https://reactome.org/PathwayBrowser/#/R-SSC-392870 Gs activation by prostacyclin receptor IEA Sus scrofa A0A287AHC5 R-SSC-3965444 https://reactome.org/PathwayBrowser/#/R-SSC-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Sus scrofa A0A287AHC5 R-SSC-3965447 https://reactome.org/PathwayBrowser/#/R-SSC-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Sus scrofa A0A287AHC5 R-SSC-396996 https://reactome.org/PathwayBrowser/#/R-SSC-396996 Thrombin-activated PARs binds G-protein Gq IEA Sus scrofa A0A287AHC5 R-SSC-397835 https://reactome.org/PathwayBrowser/#/R-SSC-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Sus scrofa A0A287AHC5 R-SSC-397891 https://reactome.org/PathwayBrowser/#/R-SSC-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Sus scrofa A0A287AHC5 R-SSC-398040 https://reactome.org/PathwayBrowser/#/R-SSC-398040 Gbeta:gamma activation of PLC beta IEA Sus scrofa A0A287AHC5 R-SSC-398193 https://reactome.org/PathwayBrowser/#/R-SSC-398193 PLC beta-mediated PIP2 hydrolysis IEA Sus scrofa A0A287AHC5 R-SSC-400037 https://reactome.org/PathwayBrowser/#/R-SSC-400037 Gi,Go Heterotrimeric G-protein complex dissociates IEA Sus scrofa A0A287AHC5 R-SSC-400092 https://reactome.org/PathwayBrowser/#/R-SSC-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Sus scrofa A0A287AHC5 R-SSC-400097 https://reactome.org/PathwayBrowser/#/R-SSC-400097 G-beta:G-gamma inhibits Adenylate cyclase IEA Sus scrofa A0A287AHC5 R-SSC-418576 https://reactome.org/PathwayBrowser/#/R-SSC-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Sus scrofa A0A287AHC5 R-SSC-420883 https://reactome.org/PathwayBrowser/#/R-SSC-420883 Opsins act as GEFs for G alpha-t IEA Sus scrofa A0A287AHC5 R-SSC-428749 https://reactome.org/PathwayBrowser/#/R-SSC-428749 Activated TP receptor binds G-proten Gq IEA Sus scrofa A0A287AHC5 R-SSC-428750 https://reactome.org/PathwayBrowser/#/R-SSC-428750 Gq activation by TP receptor IEA Sus scrofa A0A287AHC5 R-SSC-428752 https://reactome.org/PathwayBrowser/#/R-SSC-428752 Dissociation of the TP:Gq complex IEA Sus scrofa A0A287AHC5 R-SSC-428909 https://reactome.org/PathwayBrowser/#/R-SSC-428909 Activated TP receptor binds G-protein G13 IEA Sus scrofa A0A287AHC5 R-SSC-428917 https://reactome.org/PathwayBrowser/#/R-SSC-428917 G13 activation by TP receptor IEA Sus scrofa A0A287AHC5 R-SSC-428918 https://reactome.org/PathwayBrowser/#/R-SSC-428918 Dissociation of the TP:G13 complex IEA Sus scrofa A0A287AHC5 R-SSC-432195 https://reactome.org/PathwayBrowser/#/R-SSC-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Sus scrofa A0A287AHC5 R-SSC-500717 https://reactome.org/PathwayBrowser/#/R-SSC-500717 Activation of GRIK3 homomer IEA Sus scrofa A0A287AHC5 R-SSC-6814418 https://reactome.org/PathwayBrowser/#/R-SSC-6814418 PDCL promotes formation of G-beta:G-gamma heterodimers IEA Sus scrofa A0A287AHC5 R-SSC-749446 https://reactome.org/PathwayBrowser/#/R-SSC-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Sus scrofa A0A287AHC5 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287AHC5 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287AHC5 R-SSC-749453 https://reactome.org/PathwayBrowser/#/R-SSC-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Sus scrofa A0A287AHC5 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287AHC5 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287AHC5 R-SSC-750988 https://reactome.org/PathwayBrowser/#/R-SSC-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Sus scrofa A0A287AHC5 R-SSC-750993 https://reactome.org/PathwayBrowser/#/R-SSC-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Sus scrofa A0A287AHC5 R-SSC-751001 https://reactome.org/PathwayBrowser/#/R-SSC-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Sus scrofa A0A287AHC5 R-SSC-751019 https://reactome.org/PathwayBrowser/#/R-SSC-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Sus scrofa A0A287AHC5 R-SSC-751024 https://reactome.org/PathwayBrowser/#/R-SSC-751024 The Ligand:GPCR:Gz complex dissociates IEA Sus scrofa A0A287AHC5 R-SSC-751027 https://reactome.org/PathwayBrowser/#/R-SSC-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Sus scrofa A0A287AHC5 R-SSC-751029 https://reactome.org/PathwayBrowser/#/R-SSC-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Sus scrofa A0A287AHC5 R-SSC-751039 https://reactome.org/PathwayBrowser/#/R-SSC-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Sus scrofa A0A287AHC5 R-SSC-8850560 https://reactome.org/PathwayBrowser/#/R-SSC-8850560 G-protein alpha releases G-protein heterotrimer from PDCL IEA Sus scrofa A0A287AHC5 R-SSC-8964241 https://reactome.org/PathwayBrowser/#/R-SSC-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Sus scrofa A0A287AHC5 R-SSC-8964271 https://reactome.org/PathwayBrowser/#/R-SSC-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Sus scrofa A0A287AHC5 R-SSC-8964317 https://reactome.org/PathwayBrowser/#/R-SSC-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Sus scrofa A0A287AHC5 R-SSC-8964599 https://reactome.org/PathwayBrowser/#/R-SSC-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Sus scrofa A0A287AHC5 R-SSC-8964604 https://reactome.org/PathwayBrowser/#/R-SSC-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Sus scrofa A0A287AHC5 R-SSC-8964605 https://reactome.org/PathwayBrowser/#/R-SSC-8964605 PAK1:ARHGEF6 complex binds G-protein beta-gamma complex IEA Sus scrofa A0A287AHC5 R-SSC-8964614 https://reactome.org/PathwayBrowser/#/R-SSC-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Sus scrofa A0A287AHC5 R-SSC-8964634 https://reactome.org/PathwayBrowser/#/R-SSC-8964634 CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex IEA Sus scrofa A0A287AHC5 R-SSC-8982637 https://reactome.org/PathwayBrowser/#/R-SSC-8982637 Opsins binds G alpha-t IEA Sus scrofa A0A287AHC5 R-SSC-8982640 https://reactome.org/PathwayBrowser/#/R-SSC-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Sus scrofa A0A287AHC5 R-SSC-9021596 https://reactome.org/PathwayBrowser/#/R-SSC-9021596 Membrane estrogen receptors bind SRC IEA Sus scrofa A0A287AHC5 R-SSC-9021600 https://reactome.org/PathwayBrowser/#/R-SSC-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Sus scrofa A0A287AHC5 R-SSC-9021601 https://reactome.org/PathwayBrowser/#/R-SSC-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Sus scrofa A0A287AHC5 R-SSC-9036301 https://reactome.org/PathwayBrowser/#/R-SSC-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Sus scrofa A0A287AHC5 R-SSC-9036307 https://reactome.org/PathwayBrowser/#/R-SSC-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Sus scrofa A0A287AHC5 R-SSC-9728664 https://reactome.org/PathwayBrowser/#/R-SSC-9728664 GLP1R binds GLP1R agonists IEA Sus scrofa A0A287AHC5 R-SSC-9861324 https://reactome.org/PathwayBrowser/#/R-SSC-9861324 ADM:CALCRL:RAMP2:G-alpha(s):GDP:G-beta:G-gamma exchanges GDP for GTP IEA Sus scrofa A0A287AHD2 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A287AHD2 R-SSC-927830 https://reactome.org/PathwayBrowser/#/R-SSC-927830 Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex IEA Sus scrofa A0A287AHD2 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A287AHD3 R-SSC-9647746 https://reactome.org/PathwayBrowser/#/R-SSC-9647746 EML4 trimerizes IEA Sus scrofa A0A287AHD3 R-SSC-9648017 https://reactome.org/PathwayBrowser/#/R-SSC-9648017 EML4 binds to microtubules IEA Sus scrofa A0A287AHD3 R-SSC-9648089 https://reactome.org/PathwayBrowser/#/R-SSC-9648089 NEK6 and NEK7 phosphorylate EML4 IEA Sus scrofa A0A287AHD3 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287AHD4 R-SSC-1454757 https://reactome.org/PathwayBrowser/#/R-SSC-1454757 Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 IEA Sus scrofa A0A287AHD4 R-SSC-1564169 https://reactome.org/PathwayBrowser/#/R-SSC-1564169 Collagen type VIII degradation by MMP1 IEA Sus scrofa A0A287AHD4 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa A0A287AHD4 R-SSC-1981104 https://reactome.org/PathwayBrowser/#/R-SSC-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Sus scrofa A0A287AHD4 R-SSC-1981120 https://reactome.org/PathwayBrowser/#/R-SSC-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Sus scrofa A0A287AHD4 R-SSC-1981128 https://reactome.org/PathwayBrowser/#/R-SSC-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Sus scrofa A0A287AHD4 R-SSC-1981157 https://reactome.org/PathwayBrowser/#/R-SSC-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Sus scrofa A0A287AHD4 R-SSC-2002460 https://reactome.org/PathwayBrowser/#/R-SSC-2002460 P4HB binds Collagen chains IEA Sus scrofa A0A287AHD4 R-SSC-2089971 https://reactome.org/PathwayBrowser/#/R-SSC-2089971 Secretion of collagens IEA Sus scrofa A0A287AHD4 R-SSC-2213207 https://reactome.org/PathwayBrowser/#/R-SSC-2213207 Formation of collagen networks IEA Sus scrofa A0A287AHD4 R-SSC-2327695 https://reactome.org/PathwayBrowser/#/R-SSC-2327695 Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 IEA Sus scrofa A0A287AHD4 R-SSC-8944218 https://reactome.org/PathwayBrowser/#/R-SSC-8944218 Association of procollagen type VIII IEA Sus scrofa A0A287AHD4 R-SSC-8948219 https://reactome.org/PathwayBrowser/#/R-SSC-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A287AHD4 R-SSC-8948222 https://reactome.org/PathwayBrowser/#/R-SSC-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287AHD4 R-SSC-8948224 https://reactome.org/PathwayBrowser/#/R-SSC-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287AHD4 R-SSC-8948228 https://reactome.org/PathwayBrowser/#/R-SSC-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A287AHD4 R-SSC-8948231 https://reactome.org/PathwayBrowser/#/R-SSC-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287AHD4 R-SSC-8948232 https://reactome.org/PathwayBrowser/#/R-SSC-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Sus scrofa A0A287AHD4 R-SSC-8948234 https://reactome.org/PathwayBrowser/#/R-SSC-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Sus scrofa A0A287AHG3 R-SSC-9005980 https://reactome.org/PathwayBrowser/#/R-SSC-9005980 IL21 binds IL21R:JAK1 IEA Sus scrofa A0A287AHG3 R-SSC-9006844 https://reactome.org/PathwayBrowser/#/R-SSC-9006844 IL21:IL21R:JAK1 binds IL2RG:JAK3 IEA Sus scrofa A0A287AHG3 R-SSC-9006850 https://reactome.org/PathwayBrowser/#/R-SSC-9006850 IL21 receptor JAK phosphorylation IEA Sus scrofa A0A287AHG3 R-SSC-9006870 https://reactome.org/PathwayBrowser/#/R-SSC-9006870 IL21 receptor STAT phosphorylation IEA Sus scrofa A0A287AHG3 R-SSC-9006873 https://reactome.org/PathwayBrowser/#/R-SSC-9006873 IL21 receptor STAT binding IEA Sus scrofa A0A287AHG5 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A287AHG5 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A287AHG5 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287AHG5 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287AHG5 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287AHG5 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287AHG5 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287AHG5 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287AHG5 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287AHG5 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287AHG5 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287AHH7 R-SSC-109903 https://reactome.org/PathwayBrowser/#/R-SSC-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Sus scrofa A0A287AHI6 R-SSC-5694409 https://reactome.org/PathwayBrowser/#/R-SSC-5694409 Nucleotide exchange on RAB1 IEA Sus scrofa A0A287AHI6 R-SSC-5694418 https://reactome.org/PathwayBrowser/#/R-SSC-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Sus scrofa A0A287AHI7 R-SSC-8848663 https://reactome.org/PathwayBrowser/#/R-SSC-8848663 ADIPOQ trimer binds ADIPOR dimers IEA Sus scrofa A0A287AHK1 R-SSC-209738 https://reactome.org/PathwayBrowser/#/R-SSC-209738 VD3 binds GC IEA Sus scrofa A0A287AHK1 R-SSC-209944 https://reactome.org/PathwayBrowser/#/R-SSC-209944 25(OH)D binds GC IEA Sus scrofa A0A287AHK1 R-SSC-8963851 https://reactome.org/PathwayBrowser/#/R-SSC-8963851 VD3 dissociates from GC IEA Sus scrofa A0A287AHK8 R-SSC-376364 https://reactome.org/PathwayBrowser/#/R-SSC-376364 Vamp8 associated secretory vesicle to plasma membrane transport IEA Sus scrofa A0A287AHK8 R-SSC-376369 https://reactome.org/PathwayBrowser/#/R-SSC-376369 Vamp2 associated secretory vesicle to plasma membrane transport IEA Sus scrofa A0A287AHK8 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A287AHK8 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A287AHK8 R-SSC-8863973 https://reactome.org/PathwayBrowser/#/R-SSC-8863973 Fusion of ERC and phagosome IEA Sus scrofa A0A287AHK8 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa A0A287AHK8 R-SSC-9013024 https://reactome.org/PathwayBrowser/#/R-SSC-9013024 RHOB binds effectors at the plasma membrane IEA Sus scrofa A0A287AHK8 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A287AHK8 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A287AHK8 R-SSC-9018746 https://reactome.org/PathwayBrowser/#/R-SSC-9018746 RHOQ binds effectors at the plasma membrane IEA Sus scrofa A0A287AHK8 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa A0A287AHK8 R-SSC-9693125 https://reactome.org/PathwayBrowser/#/R-SSC-9693125 RHOF binds effectors at the plasma membrane IEA Sus scrofa A0A287AHL0 R-SSC-203797 https://reactome.org/PathwayBrowser/#/R-SSC-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Sus scrofa A0A287AHN9 R-SSC-1878002 https://reactome.org/PathwayBrowser/#/R-SSC-1878002 XYLTs transfer Xyl to core protein IEA Sus scrofa A0A287AHN9 R-SSC-1889955 https://reactome.org/PathwayBrowser/#/R-SSC-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Sus scrofa A0A287AHN9 R-SSC-1889978 https://reactome.org/PathwayBrowser/#/R-SSC-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Sus scrofa A0A287AHN9 R-SSC-1889981 https://reactome.org/PathwayBrowser/#/R-SSC-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Sus scrofa A0A287AHN9 R-SSC-1971482 https://reactome.org/PathwayBrowser/#/R-SSC-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Sus scrofa A0A287AHN9 R-SSC-1971483 https://reactome.org/PathwayBrowser/#/R-SSC-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Sus scrofa A0A287AHN9 R-SSC-1971487 https://reactome.org/PathwayBrowser/#/R-SSC-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Sus scrofa A0A287AHN9 R-SSC-1971491 https://reactome.org/PathwayBrowser/#/R-SSC-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Sus scrofa A0A287AHN9 R-SSC-2018659 https://reactome.org/PathwayBrowser/#/R-SSC-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Sus scrofa A0A287AHN9 R-SSC-2018682 https://reactome.org/PathwayBrowser/#/R-SSC-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Sus scrofa A0A287AHN9 R-SSC-2022052 https://reactome.org/PathwayBrowser/#/R-SSC-2022052 Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS) IEA Sus scrofa A0A287AHN9 R-SSC-2022056 https://reactome.org/PathwayBrowser/#/R-SSC-2022056 DSPG and CSPG translocate to the lysosome for degradation IEA Sus scrofa A0A287AHN9 R-SSC-2022061 https://reactome.org/PathwayBrowser/#/R-SSC-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Sus scrofa A0A287AHN9 R-SSC-2022063 https://reactome.org/PathwayBrowser/#/R-SSC-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Sus scrofa A0A287AHN9 R-SSC-2022065 https://reactome.org/PathwayBrowser/#/R-SSC-2022065 DSPGs are secreted IEA Sus scrofa A0A287AHN9 R-SSC-2022911 https://reactome.org/PathwayBrowser/#/R-SSC-2022911 CSPG is secreted IEA Sus scrofa A0A287AHN9 R-SSC-2424246 https://reactome.org/PathwayBrowser/#/R-SSC-2424246 Tenascins C, R, (X, N) bind lecticans IEA Sus scrofa A0A287AHN9 R-SSC-3788075 https://reactome.org/PathwayBrowser/#/R-SSC-3788075 Brevican degradation by ADAMTS4, ADAMTS5 IEA Sus scrofa A0A287AHN9 R-SSC-3791149 https://reactome.org/PathwayBrowser/#/R-SSC-3791149 Brevican degradation by MMP1, 2, 3, 7,8,10,13,19 IEA Sus scrofa A0A287AHN9 R-SSC-9632033 https://reactome.org/PathwayBrowser/#/R-SSC-9632033 CHSY1 transfers GalNAc to chondroitin IEA Sus scrofa A0A287AHN9 R-SSC-9632034 https://reactome.org/PathwayBrowser/#/R-SSC-9632034 CHSY1 transfers GlcA to chondroitin IEA Sus scrofa A0A287AHN9 R-SSC-9638064 https://reactome.org/PathwayBrowser/#/R-SSC-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Sus scrofa A0A287AHP2 R-SSC-8952631 https://reactome.org/PathwayBrowser/#/R-SSC-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AHP2 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287AHP2 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AHP2 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AHP2 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AHP2 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287AHP2 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AHP2 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AHP5 R-SSC-9933559 https://reactome.org/PathwayBrowser/#/R-SSC-9933559 The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1 IEA Sus scrofa A0A287AHP5 R-SSC-9933575 https://reactome.org/PathwayBrowser/#/R-SSC-9933575 MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome IEA Sus scrofa A0A287AHP5 R-SSC-9933585 https://reactome.org/PathwayBrowser/#/R-SSC-9933585 RNA exosome in PAXT:PAPOLG:TENT4A,B:ZC3H3:CBCA:polyadenylated m7GpppN-RNA:PABPN1 hydrolyzes RNA IEA Sus scrofa A0A287AHT1 R-SSC-203946 https://reactome.org/PathwayBrowser/#/R-SSC-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Sus scrofa A0A287AHU1 R-SSC-429955 https://reactome.org/PathwayBrowser/#/R-SSC-429955 CCR4-NOT complex deadenylates mRNA IEA Sus scrofa A0A287AHU1 R-SSC-429992 https://reactome.org/PathwayBrowser/#/R-SSC-429992 PARN deadenylates mRNA IEA Sus scrofa A0A287AHU1 R-SSC-430021 https://reactome.org/PathwayBrowser/#/R-SSC-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Sus scrofa A0A287AHU3 R-SSC-110307 https://reactome.org/PathwayBrowser/#/R-SSC-110307 REV1 binds AP-dsDNA IEA Sus scrofa A0A287AHU3 R-SSC-110308 https://reactome.org/PathwayBrowser/#/R-SSC-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Sus scrofa A0A287AHU3 R-SSC-110311 https://reactome.org/PathwayBrowser/#/R-SSC-110311 POLZ extends translesion synthesis IEA Sus scrofa A0A287AHU3 R-SSC-110316 https://reactome.org/PathwayBrowser/#/R-SSC-110316 POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template IEA Sus scrofa A0A287AHU3 R-SSC-110317 https://reactome.org/PathwayBrowser/#/R-SSC-110317 Insertion of correct bases opposite the lesion by POLH IEA Sus scrofa A0A287AHU3 R-SSC-110319 https://reactome.org/PathwayBrowser/#/R-SSC-110319 Elongation by POLH IEA Sus scrofa A0A287AHU3 R-SSC-110364 https://reactome.org/PathwayBrowser/#/R-SSC-110364 PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 IEA Sus scrofa A0A287AHU3 R-SSC-110368 https://reactome.org/PathwayBrowser/#/R-SSC-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Sus scrofa A0A287AHU3 R-SSC-110371 https://reactome.org/PathwayBrowser/#/R-SSC-110371 LIG1 binds APEX1 and PCNA at SSB IEA Sus scrofa A0A287AHU3 R-SSC-174439 https://reactome.org/PathwayBrowser/#/R-SSC-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Sus scrofa A0A287AHU3 R-SSC-174447 https://reactome.org/PathwayBrowser/#/R-SSC-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Sus scrofa A0A287AHU3 R-SSC-174452 https://reactome.org/PathwayBrowser/#/R-SSC-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Sus scrofa A0A287AHU3 R-SSC-176101 https://reactome.org/PathwayBrowser/#/R-SSC-176101 Recruitment of Rad17-RFC complex to DNA IEA Sus scrofa A0A287AHU3 R-SSC-176264 https://reactome.org/PathwayBrowser/#/R-SSC-176264 Recruitment of the Rad9-Hus1-Rad1 complex to DNA IEA Sus scrofa A0A287AHU3 R-SSC-5651805 https://reactome.org/PathwayBrowser/#/R-SSC-5651805 LIG1 bound to APEX1 and PCNA ligates SSB IEA Sus scrofa A0A287AHU3 R-SSC-5652005 https://reactome.org/PathwayBrowser/#/R-SSC-5652005 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA IEA Sus scrofa A0A287AHU3 R-SSC-5652009 https://reactome.org/PathwayBrowser/#/R-SSC-5652009 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA IEA Sus scrofa A0A287AHU3 R-SSC-5652151 https://reactome.org/PathwayBrowser/#/R-SSC-5652151 REV1 recruits POLZ to (AP:Cyt)-DNA Template IEA Sus scrofa A0A287AHU3 R-SSC-5653754 https://reactome.org/PathwayBrowser/#/R-SSC-5653754 UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA IEA Sus scrofa A0A287AHU3 R-SSC-5653756 https://reactome.org/PathwayBrowser/#/R-SSC-5653756 TRIM25 binds monoUb:164-PCNA IEA Sus scrofa A0A287AHU3 R-SSC-5653766 https://reactome.org/PathwayBrowser/#/R-SSC-5653766 USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A287AHU3 R-SSC-5653770 https://reactome.org/PathwayBrowser/#/R-SSC-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A287AHU3 R-SSC-5653780 https://reactome.org/PathwayBrowser/#/R-SSC-5653780 USP43 binds ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A287AHU3 R-SSC-5653786 https://reactome.org/PathwayBrowser/#/R-SSC-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A287AHU3 R-SSC-5653838 https://reactome.org/PathwayBrowser/#/R-SSC-5653838 POLD,POLE binds deISGylated PCNA after TLS IEA Sus scrofa A0A287AHU3 R-SSC-5654985 https://reactome.org/PathwayBrowser/#/R-SSC-5654985 SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH IEA Sus scrofa A0A287AHU3 R-SSC-5654986 https://reactome.org/PathwayBrowser/#/R-SSC-5654986 SPRTN binds monoUb:K164-PCNA associated with POLH IEA Sus scrofa A0A287AHU3 R-SSC-5654989 https://reactome.org/PathwayBrowser/#/R-SSC-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Sus scrofa A0A287AHU3 R-SSC-5655466 https://reactome.org/PathwayBrowser/#/R-SSC-5655466 USP1:WDR48 deubiquitinates monoUb:K164-PCNA IEA Sus scrofa A0A287AHU3 R-SSC-5655481 https://reactome.org/PathwayBrowser/#/R-SSC-5655481 USP1:WDR48 binds monoUb:K164-PCNA IEA Sus scrofa A0A287AHU3 R-SSC-5655835 https://reactome.org/PathwayBrowser/#/R-SSC-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Sus scrofa A0A287AHU3 R-SSC-5655892 https://reactome.org/PathwayBrowser/#/R-SSC-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Sus scrofa A0A287AHU3 R-SSC-5655965 https://reactome.org/PathwayBrowser/#/R-SSC-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Sus scrofa A0A287AHU3 R-SSC-5656105 https://reactome.org/PathwayBrowser/#/R-SSC-5656105 POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA IEA Sus scrofa A0A287AHU3 R-SSC-5656148 https://reactome.org/PathwayBrowser/#/R-SSC-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Sus scrofa A0A287AHU3 R-SSC-5656158 https://reactome.org/PathwayBrowser/#/R-SSC-5656158 POLZ elongates POLI-incorporated dNMP IEA Sus scrofa A0A287AHU3 R-SSC-5684882 https://reactome.org/PathwayBrowser/#/R-SSC-5684882 CHEK1 is recruited to resected DNA DSBs IEA Sus scrofa A0A287AHU3 R-SSC-5684887 https://reactome.org/PathwayBrowser/#/R-SSC-5684887 Activation of CHEK1 at resected DNA DSBs IEA Sus scrofa A0A287AHU3 R-SSC-5685011 https://reactome.org/PathwayBrowser/#/R-SSC-5685011 ATR activation at DNA DSBs IEA Sus scrofa A0A287AHU3 R-SSC-5685156 https://reactome.org/PathwayBrowser/#/R-SSC-5685156 ATR phosphorylates RPA2 IEA Sus scrofa A0A287AHU3 R-SSC-5686642 https://reactome.org/PathwayBrowser/#/R-SSC-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Sus scrofa A0A287AHU3 R-SSC-5686657 https://reactome.org/PathwayBrowser/#/R-SSC-5686657 ERCC1:XPF cleaves flaps generated by SSA IEA Sus scrofa A0A287AHU3 R-SSC-5690213 https://reactome.org/PathwayBrowser/#/R-SSC-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Sus scrofa A0A287AHU3 R-SSC-5690988 https://reactome.org/PathwayBrowser/#/R-SSC-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Sus scrofa A0A287AHU3 R-SSC-5691001 https://reactome.org/PathwayBrowser/#/R-SSC-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Sus scrofa A0A287AHU3 R-SSC-5693564 https://reactome.org/PathwayBrowser/#/R-SSC-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Sus scrofa A0A287AHU3 R-SSC-5693580 https://reactome.org/PathwayBrowser/#/R-SSC-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Sus scrofa A0A287AHU3 R-SSC-5693593 https://reactome.org/PathwayBrowser/#/R-SSC-5693593 D-loop extension by DNA polymerases IEA Sus scrofa A0A287AHU3 R-SSC-6782208 https://reactome.org/PathwayBrowser/#/R-SSC-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Sus scrofa A0A287AHU3 R-SSC-6782211 https://reactome.org/PathwayBrowser/#/R-SSC-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Sus scrofa A0A287AHU3 R-SSC-6782224 https://reactome.org/PathwayBrowser/#/R-SSC-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Sus scrofa A0A287AHU3 R-SSC-6782227 https://reactome.org/PathwayBrowser/#/R-SSC-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Sus scrofa A0A287AHU3 R-SSC-6799332 https://reactome.org/PathwayBrowser/#/R-SSC-6799332 ATR phosphorylates TP53 IEA Sus scrofa A0A287AHU3 R-SSC-69053 https://reactome.org/PathwayBrowser/#/R-SSC-69053 RFC binding displaces Pol Alpha IEA Sus scrofa A0A287AHU3 R-SSC-69063 https://reactome.org/PathwayBrowser/#/R-SSC-69063 Loading of PCNA - Sliding Clamp Formation IEA Sus scrofa A0A287AHU3 R-SSC-69068 https://reactome.org/PathwayBrowser/#/R-SSC-69068 RFC dissociates after sliding clamp formation IEA Sus scrofa A0A287AHU4 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A287AHU4 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287AHU4 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A287AHU4 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A287AHV5 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AHV9 R-SSC-8941234 https://reactome.org/PathwayBrowser/#/R-SSC-8941234 SH3PXD2A binds ADAM12,ADAM15,ADAM19 IEA Sus scrofa A0A287AHV9 R-SSC-9759522 https://reactome.org/PathwayBrowser/#/R-SSC-9759522 Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform IEA Sus scrofa A0A287AHW1 R-SSC-9821475 https://reactome.org/PathwayBrowser/#/R-SSC-9821475 CXXC1 and WDR82 bind SET1A complex IEA Sus scrofa A0A287AHW1 R-SSC-9821476 https://reactome.org/PathwayBrowser/#/R-SSC-9821476 CXXC1 and WDR82 bind SET1B complex IEA Sus scrofa A0A287AHW1 R-SSC-9821486 https://reactome.org/PathwayBrowser/#/R-SSC-9821486 HCFC1 binds SET1A complex IEA Sus scrofa A0A287AHW1 R-SSC-9821931 https://reactome.org/PathwayBrowser/#/R-SSC-9821931 BOD1L1 binds SET1A complex IEA Sus scrofa A0A287AHW3 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A287AHW3 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A287AHW3 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A287AHW3 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A287AHW3 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A287AHW3 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A287AHW3 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A287AHW3 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A287AHW3 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A287AHW3 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287AHW3 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A287AHW3 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A287AHW3 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287AHW3 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A287AHW3 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287AHW3 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287AHW3 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287AHW3 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287AHW3 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287AHW3 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A287AHW3 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A287AHW4 R-SSC-3295579 https://reactome.org/PathwayBrowser/#/R-SSC-3295579 TRPs transport extracellular Ca2+ to cytosol IEA Sus scrofa A0A287AHW4 R-SSC-9701055 https://reactome.org/PathwayBrowser/#/R-SSC-9701055 TRPA1 tetramer transports Ca2+ from extracellular region to cytosol IEA Sus scrofa A0A287AHW4 R-SSC-9701211 https://reactome.org/PathwayBrowser/#/R-SSC-9701211 TRPA1 tetramer binds TRPA1 antagonists IEA Sus scrofa A0A287AHX5 R-SSC-113503 https://reactome.org/PathwayBrowser/#/R-SSC-113503 PP2A mediated localization of RB1 protein in chromatin IEA Sus scrofa A0A287AHX5 R-SSC-1363274 https://reactome.org/PathwayBrowser/#/R-SSC-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Sus scrofa A0A287AHX5 R-SSC-1363276 https://reactome.org/PathwayBrowser/#/R-SSC-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Sus scrofa A0A287AHX5 R-SSC-8856945 https://reactome.org/PathwayBrowser/#/R-SSC-8856945 PP2A methylation by LCMT1 IEA Sus scrofa A0A287AHX5 R-SSC-8856951 https://reactome.org/PathwayBrowser/#/R-SSC-8856951 PP2A demethylation by PPME1 IEA Sus scrofa A0A287AHZ7 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A287AHZ7 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A287AHZ7 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A287AHZ7 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A287AHZ7 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A287AHZ7 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A287AHZ7 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A287AHZ7 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A287AHZ7 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A287AHZ7 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287AHZ7 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A287AHZ7 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A287AHZ7 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287AHZ7 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A287AHZ7 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287AHZ7 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287AHZ7 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287AHZ7 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287AHZ7 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287AHZ7 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A287AHZ7 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A287AI32 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A287AI56 R-SSC-199032 https://reactome.org/PathwayBrowser/#/R-SSC-199032 MADCAM1-1 binds Integrin alpha4beta7 IEA Sus scrofa A0A287AI56 R-SSC-265422 https://reactome.org/PathwayBrowser/#/R-SSC-265422 Interaction of integrin alphaEbeta7 with Cadherin-1 IEA Sus scrofa A0A287AI58 R-SSC-425482 https://reactome.org/PathwayBrowser/#/R-SSC-425482 SLC4A1,2,3 exchanges HCO3- for Cl- IEA Sus scrofa A0A287AI68 R-SSC-73805 https://reactome.org/PathwayBrowser/#/R-SSC-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Sus scrofa A0A287AI68 R-SSC-73806 https://reactome.org/PathwayBrowser/#/R-SSC-73806 AIR + CO2 => CAIR IEA Sus scrofa A0A287AI89 R-SSC-5661217 https://reactome.org/PathwayBrowser/#/R-SSC-5661217 MT1A binds zinc IEA Sus scrofa A0A287AI89 R-SSC-5661230 https://reactome.org/PathwayBrowser/#/R-SSC-5661230 MT1A binds arsenic IEA Sus scrofa A0A287AI92 R-SSC-1475022 https://reactome.org/PathwayBrowser/#/R-SSC-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Sus scrofa A0A287AI92 R-SSC-1475026 https://reactome.org/PathwayBrowser/#/R-SSC-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Sus scrofa A0A287AI92 R-SSC-1475435 https://reactome.org/PathwayBrowser/#/R-SSC-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Sus scrofa A0A287AI92 R-SSC-1475436 https://reactome.org/PathwayBrowser/#/R-SSC-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Sus scrofa A0A287AI92 R-SSC-9707419 https://reactome.org/PathwayBrowser/#/R-SSC-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Sus scrofa A0A287AIB9 R-SSC-9909510 https://reactome.org/PathwayBrowser/#/R-SSC-9909510 FKBP5 binds CHUK:IKBKB:IKBKG IEA Sus scrofa A0A287AIB9 R-SSC-9909519 https://reactome.org/PathwayBrowser/#/R-SSC-9909519 IFI44, IFI44L binds FKBP5 IEA Sus scrofa A0A287AIC4 R-SSC-8980691 https://reactome.org/PathwayBrowser/#/R-SSC-8980691 RHOA GEFs activate RHOA IEA Sus scrofa A0A287AIC4 R-SSC-8981637 https://reactome.org/PathwayBrowser/#/R-SSC-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Sus scrofa A0A287AIC4 R-SSC-9013022 https://reactome.org/PathwayBrowser/#/R-SSC-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Sus scrofa A0A287AIC4 R-SSC-9013024 https://reactome.org/PathwayBrowser/#/R-SSC-9013024 RHOB binds effectors at the plasma membrane IEA Sus scrofa A0A287AIC4 R-SSC-9013110 https://reactome.org/PathwayBrowser/#/R-SSC-9013110 RHOC binds effectors at the plasma membrane IEA Sus scrofa A0A287AIC4 R-SSC-9013111 https://reactome.org/PathwayBrowser/#/R-SSC-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Sus scrofa A0A287AIC4 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A287AIC4 R-SSC-9013144 https://reactome.org/PathwayBrowser/#/R-SSC-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Sus scrofa A0A287AIC4 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa A0A287AIC4 R-SSC-9013161 https://reactome.org/PathwayBrowser/#/R-SSC-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Sus scrofa A0A287AIC4 R-SSC-9014295 https://reactome.org/PathwayBrowser/#/R-SSC-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Sus scrofa A0A287AIC4 R-SSC-9014296 https://reactome.org/PathwayBrowser/#/R-SSC-9014296 RAC2 GEFs activate RAC2 IEA Sus scrofa A0A287AIC4 R-SSC-9018806 https://reactome.org/PathwayBrowser/#/R-SSC-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Sus scrofa A0A287AID0 R-SSC-6791218 https://reactome.org/PathwayBrowser/#/R-SSC-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Sus scrofa A0A287AID3 R-SSC-110137 https://reactome.org/PathwayBrowser/#/R-SSC-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Sus scrofa A0A287AID3 R-SSC-110138 https://reactome.org/PathwayBrowser/#/R-SSC-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa A0A287AIE4 R-SSC-8952631 https://reactome.org/PathwayBrowser/#/R-SSC-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AIE4 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287AIE4 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AIE4 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AIE4 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AIE4 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287AIE4 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AIE4 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AIE7 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A287AIE7 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa A0A287AIE7 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa A0A287AIE7 R-SSC-983259 https://reactome.org/PathwayBrowser/#/R-SSC-983259 Kinesins move along microtubules consuming ATP IEA Sus scrofa A0A287AIE7 R-SSC-983266 https://reactome.org/PathwayBrowser/#/R-SSC-983266 Kinesins bind microtubules IEA Sus scrofa A0A287AIG0 R-SSC-110307 https://reactome.org/PathwayBrowser/#/R-SSC-110307 REV1 binds AP-dsDNA IEA Sus scrofa A0A287AIG0 R-SSC-110308 https://reactome.org/PathwayBrowser/#/R-SSC-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Sus scrofa A0A287AIG0 R-SSC-110311 https://reactome.org/PathwayBrowser/#/R-SSC-110311 POLZ extends translesion synthesis IEA Sus scrofa A0A287AIG0 R-SSC-5652151 https://reactome.org/PathwayBrowser/#/R-SSC-5652151 REV1 recruits POLZ to (AP:Cyt)-DNA Template IEA Sus scrofa A0A287AIG0 R-SSC-5653754 https://reactome.org/PathwayBrowser/#/R-SSC-5653754 UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA IEA Sus scrofa A0A287AIG0 R-SSC-5653756 https://reactome.org/PathwayBrowser/#/R-SSC-5653756 TRIM25 binds monoUb:164-PCNA IEA Sus scrofa A0A287AIG0 R-SSC-5653766 https://reactome.org/PathwayBrowser/#/R-SSC-5653766 USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A287AIG0 R-SSC-5653770 https://reactome.org/PathwayBrowser/#/R-SSC-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A287AIG0 R-SSC-5655835 https://reactome.org/PathwayBrowser/#/R-SSC-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Sus scrofa A0A287AIG0 R-SSC-5655892 https://reactome.org/PathwayBrowser/#/R-SSC-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Sus scrofa A0A287AIG0 R-SSC-5655965 https://reactome.org/PathwayBrowser/#/R-SSC-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Sus scrofa A0A287AIG0 R-SSC-5656105 https://reactome.org/PathwayBrowser/#/R-SSC-5656105 POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA IEA Sus scrofa A0A287AIG0 R-SSC-5656148 https://reactome.org/PathwayBrowser/#/R-SSC-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Sus scrofa A0A287AIG0 R-SSC-5656158 https://reactome.org/PathwayBrowser/#/R-SSC-5656158 POLZ elongates POLI-incorporated dNMP IEA Sus scrofa A0A287AIG4 R-SSC-1296348 https://reactome.org/PathwayBrowser/#/R-SSC-1296348 Activation of TWIK-related K+ channel (TREK) IEA Sus scrofa A0A287AIG4 R-SSC-5578910 https://reactome.org/PathwayBrowser/#/R-SSC-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Sus scrofa A0A287AII8 R-SSC-3322005 https://reactome.org/PathwayBrowser/#/R-SSC-3322005 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a IEA Sus scrofa A0A287AII8 R-SSC-3322016 https://reactome.org/PathwayBrowser/#/R-SSC-3322016 GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a IEA Sus scrofa A0A287AII8 R-SSC-3322057 https://reactome.org/PathwayBrowser/#/R-SSC-3322057 GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b IEA Sus scrofa A0A287AIJ3 R-SSC-3341397 https://reactome.org/PathwayBrowser/#/R-SSC-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa A0A287AIK7 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A287AIK7 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A287AIK7 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A287AIK7 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A287AIK7 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287AIK7 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287AIK7 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287AIK7 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287AIK7 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287AIK7 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287AIK7 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A287AIK7 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A287AIK7 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A287AIK7 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A287AIK7 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287AIL5 R-SSC-111962 https://reactome.org/PathwayBrowser/#/R-SSC-111962 PDE4A,C,D hydrolyse cAMP IEA Sus scrofa A0A287AIL5 R-SSC-418553 https://reactome.org/PathwayBrowser/#/R-SSC-418553 cAMP degradation by Phosphodiesterases IEA Sus scrofa A0A287AIL5 R-SSC-9708261 https://reactome.org/PathwayBrowser/#/R-SSC-9708261 PDE4A hydrolyses cAMP to AMP IEA Sus scrofa A0A287AIL5 R-SSC-9708275 https://reactome.org/PathwayBrowser/#/R-SSC-9708275 PDE4A binds PDE4A inhibitors IEA Sus scrofa A0A287AIM8 R-SSC-173680 https://reactome.org/PathwayBrowser/#/R-SSC-173680 Activation of C5 IEA Sus scrofa A0A287AIM8 R-SSC-173705 https://reactome.org/PathwayBrowser/#/R-SSC-173705 C5b binds C6 IEA Sus scrofa A0A287AIM8 R-SSC-173709 https://reactome.org/PathwayBrowser/#/R-SSC-173709 C7 binds C5b:C6 IEA Sus scrofa A0A287AIM8 R-SSC-173720 https://reactome.org/PathwayBrowser/#/R-SSC-173720 C5b:C6:C7 translocates to the plasma membrane IEA Sus scrofa A0A287AIM8 R-SSC-173723 https://reactome.org/PathwayBrowser/#/R-SSC-173723 C8 binds C5b:C6:C7 IEA Sus scrofa A0A287AIM8 R-SSC-173725 https://reactome.org/PathwayBrowser/#/R-SSC-173725 C9 binds C5b:C6:C7:C8 IEA Sus scrofa A0A287AIM8 R-SSC-2530429 https://reactome.org/PathwayBrowser/#/R-SSC-2530429 Formation of soluble VTN:C5b-C9 IEA Sus scrofa A0A287AIM8 R-SSC-2530445 https://reactome.org/PathwayBrowser/#/R-SSC-2530445 CD59 inhibits MAC formation IEA Sus scrofa A0A287AIM8 R-SSC-2530453 https://reactome.org/PathwayBrowser/#/R-SSC-2530453 Vitronectin (VTN) binds to C5b:C6:C7 IEA Sus scrofa A0A287AIM8 R-SSC-375395 https://reactome.org/PathwayBrowser/#/R-SSC-375395 C5a receptor binds C5a anaphylatoxin IEA Sus scrofa A0A287AIM8 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287AIM8 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287AIM8 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287AIM8 R-SSC-8852580 https://reactome.org/PathwayBrowser/#/R-SSC-8852580 Clusterin binds C5b-C7, C8, C9 IEA Sus scrofa A0A287AIM8 R-SSC-8852716 https://reactome.org/PathwayBrowser/#/R-SSC-8852716 Thrombin, ELANE cleave C5 IEA Sus scrofa A0A287AIM8 R-SSC-8852809 https://reactome.org/PathwayBrowser/#/R-SSC-8852809 CPN, CPB2 cleave C3a, C5a IEA Sus scrofa A0A287AIM8 R-SSC-964811 https://reactome.org/PathwayBrowser/#/R-SSC-964811 C5AR2 binds anaphylatoxins and thier desArginated derivatives IEA Sus scrofa A0A287AIM8 R-SSC-9691621 https://reactome.org/PathwayBrowser/#/R-SSC-9691621 C5 binds C5 inhibitors IEA Sus scrofa A0A287AIM9 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa A0A287AIM9 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa A0A287AIM9 R-SSC-8980691 https://reactome.org/PathwayBrowser/#/R-SSC-8980691 RHOA GEFs activate RHOA IEA Sus scrofa A0A287AIM9 R-SSC-9013023 https://reactome.org/PathwayBrowser/#/R-SSC-9013023 RHOB GEFs activate RHOB IEA Sus scrofa A0A287AIM9 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A287AIM9 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa A0A287AIN4 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AIN4 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287AIN4 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AIN4 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AIP7 R-SSC-201035 https://reactome.org/PathwayBrowser/#/R-SSC-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Sus scrofa A0A287AIP7 R-SSC-2046085 https://reactome.org/PathwayBrowser/#/R-SSC-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Sus scrofa A0A287AIP7 R-SSC-2046098 https://reactome.org/PathwayBrowser/#/R-SSC-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Sus scrofa A0A287AIP9 R-SSC-5159245 https://reactome.org/PathwayBrowser/#/R-SSC-5159245 SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) IEA Sus scrofa A0A287AIQ7 R-SSC-9708457 https://reactome.org/PathwayBrowser/#/R-SSC-9708457 HM13 cleaves HMOX1 dimer IEA Sus scrofa A0A287AIR5 R-SSC-6788523 https://reactome.org/PathwayBrowser/#/R-SSC-6788523 NUBPL transfers 4Fe-4S to Complex I subunits IEA Sus scrofa A0A287AIR5 R-SSC-6788556 https://reactome.org/PathwayBrowser/#/R-SSC-6788556 NUBPL transfers 4Fe-4S to NDUFV1, V2 IEA Sus scrofa A0A287AIR5 R-SSC-8878815 https://reactome.org/PathwayBrowser/#/R-SSC-8878815 Formation of 4Fe-4S cluster on ISCA1:ISCA2 IEA Sus scrofa A0A287AIR5 R-SSC-8986181 https://reactome.org/PathwayBrowser/#/R-SSC-8986181 PITRM1 proteolyzes mitochondrial targeting peptides (presequences) IEA Sus scrofa A0A287AIR5 R-SSC-9866272 https://reactome.org/PathwayBrowser/#/R-SSC-9866272 2Fe-2S is inserted in UQCRFS1 IEA Sus scrofa A0A287AIR9 R-SSC-427514 https://reactome.org/PathwayBrowser/#/R-SSC-427514 eNoSC deacetylates histone H3 IEA Sus scrofa A0A287AIR9 R-SSC-427527 https://reactome.org/PathwayBrowser/#/R-SSC-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Sus scrofa A0A287AIR9 R-SSC-427528 https://reactome.org/PathwayBrowser/#/R-SSC-427528 Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) IEA Sus scrofa A0A287AIR9 R-SSC-4827382 https://reactome.org/PathwayBrowser/#/R-SSC-4827382 SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) IEA Sus scrofa A0A287AIU0 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A287AIU3 R-SSC-913675 https://reactome.org/PathwayBrowser/#/R-SSC-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Sus scrofa A0A287AIU8 R-SSC-139908 https://reactome.org/PathwayBrowser/#/R-SSC-139908 Phosphorylation of DLC2 by MAPK8 IEA Sus scrofa A0A287AIU8 R-SSC-139909 https://reactome.org/PathwayBrowser/#/R-SSC-139909 Translocation of BMF to mitochondria IEA Sus scrofa A0A287AIU8 R-SSC-508163 https://reactome.org/PathwayBrowser/#/R-SSC-508163 BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 IEA Sus scrofa A0A287AIV4 R-SSC-1362270 https://reactome.org/PathwayBrowser/#/R-SSC-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Sus scrofa A0A287AIV8 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A287AIV8 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A287AIV8 R-SSC-6814695 https://reactome.org/PathwayBrowser/#/R-SSC-6814695 PERP binds desmosomes IEA Sus scrofa A0A287AIV8 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A287AIV8 R-SSC-9696266 https://reactome.org/PathwayBrowser/#/R-SSC-9696266 RND2 binds effectors IEA Sus scrofa A0A287AIV8 R-SSC-9696268 https://reactome.org/PathwayBrowser/#/R-SSC-9696268 RND3 binds effectors IEA Sus scrofa A0A287AIV8 R-SSC-9696271 https://reactome.org/PathwayBrowser/#/R-SSC-9696271 RND1 binds effectors IEA Sus scrofa A0A287AIW3 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A287AIW3 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A287AIW3 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A287AIW3 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A287AIW3 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287AIW3 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287AIW3 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A287AIW3 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287AIW3 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287AIW3 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287AIW3 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287AIW3 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A287AIW3 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa A0A287AIW3 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A287AIW3 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A287AIW3 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A287AIW3 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A287AIW3 R-SSC-6800426 https://reactome.org/PathwayBrowser/#/R-SSC-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Sus scrofa A0A287AIW3 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa A0A287AIW3 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A287AIW3 R-SSC-9646348 https://reactome.org/PathwayBrowser/#/R-SSC-9646348 PolyUb-Misfolded Proteins:HDAC6 bind dynein motor IEA Sus scrofa A0A287AIW3 R-SSC-9646679 https://reactome.org/PathwayBrowser/#/R-SSC-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Sus scrofa A0A287AIW3 R-SSC-9646685 https://reactome.org/PathwayBrowser/#/R-SSC-9646685 Aggresome dissociates from dynein and microtubule IEA Sus scrofa A0A287AIW3 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287AIW5 R-SSC-1912357 https://reactome.org/PathwayBrowser/#/R-SSC-1912357 ITCH ubiquitinates DTX IEA Sus scrofa A0A287AIW5 R-SSC-1980125 https://reactome.org/PathwayBrowser/#/R-SSC-1980125 ITCH binds DTX IEA Sus scrofa A0A287AIW5 R-SSC-2396007 https://reactome.org/PathwayBrowser/#/R-SSC-2396007 IRF3 is phosphorylated by TBK1 IEA Sus scrofa A0A287AIW5 R-SSC-3249392 https://reactome.org/PathwayBrowser/#/R-SSC-3249392 NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3 IEA Sus scrofa A0A287AIW5 R-SSC-8948709 https://reactome.org/PathwayBrowser/#/R-SSC-8948709 DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 IEA Sus scrofa A0A287AIY6 R-SSC-1878002 https://reactome.org/PathwayBrowser/#/R-SSC-1878002 XYLTs transfer Xyl to core protein IEA Sus scrofa A0A287AIY6 R-SSC-1889955 https://reactome.org/PathwayBrowser/#/R-SSC-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Sus scrofa A0A287AIY6 R-SSC-1889978 https://reactome.org/PathwayBrowser/#/R-SSC-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Sus scrofa A0A287AIY6 R-SSC-1889981 https://reactome.org/PathwayBrowser/#/R-SSC-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Sus scrofa A0A287AIY6 R-SSC-1971482 https://reactome.org/PathwayBrowser/#/R-SSC-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Sus scrofa A0A287AIY6 R-SSC-1971483 https://reactome.org/PathwayBrowser/#/R-SSC-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 IEA Sus scrofa A0A287AIY6 R-SSC-1971487 https://reactome.org/PathwayBrowser/#/R-SSC-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin IEA Sus scrofa A0A287AIY6 R-SSC-1971491 https://reactome.org/PathwayBrowser/#/R-SSC-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin IEA Sus scrofa A0A287AIY6 R-SSC-2018659 https://reactome.org/PathwayBrowser/#/R-SSC-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 IEA Sus scrofa A0A287AIY6 R-SSC-2018682 https://reactome.org/PathwayBrowser/#/R-SSC-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains IEA Sus scrofa A0A287AIY6 R-SSC-2022052 https://reactome.org/PathwayBrowser/#/R-SSC-2022052 Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS) IEA Sus scrofa A0A287AIY6 R-SSC-2022056 https://reactome.org/PathwayBrowser/#/R-SSC-2022056 DSPG and CSPG translocate to the lysosome for degradation IEA Sus scrofa A0A287AIY6 R-SSC-2022061 https://reactome.org/PathwayBrowser/#/R-SSC-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate IEA Sus scrofa A0A287AIY6 R-SSC-2022063 https://reactome.org/PathwayBrowser/#/R-SSC-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS IEA Sus scrofa A0A287AIY6 R-SSC-2022065 https://reactome.org/PathwayBrowser/#/R-SSC-2022065 DSPGs are secreted IEA Sus scrofa A0A287AIY6 R-SSC-2022911 https://reactome.org/PathwayBrowser/#/R-SSC-2022911 CSPG is secreted IEA Sus scrofa A0A287AIY6 R-SSC-9632033 https://reactome.org/PathwayBrowser/#/R-SSC-9632033 CHSY1 transfers GalNAc to chondroitin IEA Sus scrofa A0A287AIY6 R-SSC-9632034 https://reactome.org/PathwayBrowser/#/R-SSC-9632034 CHSY1 transfers GlcA to chondroitin IEA Sus scrofa A0A287AIY6 R-SSC-9638064 https://reactome.org/PathwayBrowser/#/R-SSC-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Sus scrofa A0A287AIY8 R-SSC-198958 https://reactome.org/PathwayBrowser/#/R-SSC-198958 KIR2DL2/3 interacting with HLA-C group 1 (Cw4) IEA Sus scrofa A0A287AIY8 R-SSC-199558 https://reactome.org/PathwayBrowser/#/R-SSC-199558 KIR2DL1 interacting with HLA-C group 2 (Cw3) IEA Sus scrofa A0A287AIY8 R-SSC-199566 https://reactome.org/PathwayBrowser/#/R-SSC-199566 KIR3DL1 interacting with HLA Bw4 IEA Sus scrofa A0A287AIY8 R-SSC-199583 https://reactome.org/PathwayBrowser/#/R-SSC-199583 KIR2DS2 interacting with HLA-C group 1 (Cw3) IEA Sus scrofa A0A287AIY8 R-SSC-199587 https://reactome.org/PathwayBrowser/#/R-SSC-199587 KIR2DS1 interacting with HLA-C group 2 (Cw4) IEA Sus scrofa A0A287AIY8 R-SSC-210298 https://reactome.org/PathwayBrowser/#/R-SSC-210298 Interaction of DAP12 and KIR3DS1 IEA Sus scrofa A0A287AIY8 R-SSC-210309 https://reactome.org/PathwayBrowser/#/R-SSC-210309 Interaction of DAP12 and KIR2DS2 IEA Sus scrofa A0A287AIY8 R-SSC-2272668 https://reactome.org/PathwayBrowser/#/R-SSC-2272668 Interaction of DAP12 and KIR2DS5 IEA Sus scrofa A0A287AIY8 R-SSC-2272753 https://reactome.org/PathwayBrowser/#/R-SSC-2272753 Interaction of DAP12 and KIR2DS4 IEA Sus scrofa A0A287AIY8 R-SSC-2272795 https://reactome.org/PathwayBrowser/#/R-SSC-2272795 Interaction of DAP12 and KIR2DS1 IEA Sus scrofa A0A287AJ15 R-SSC-1667005 https://reactome.org/PathwayBrowser/#/R-SSC-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Sus scrofa A0A287AJ15 R-SSC-1678694 https://reactome.org/PathwayBrowser/#/R-SSC-1678694 Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans IEA Sus scrofa A0A287AJ15 R-SSC-1878002 https://reactome.org/PathwayBrowser/#/R-SSC-1878002 XYLTs transfer Xyl to core protein IEA Sus scrofa A0A287AJ15 R-SSC-1889955 https://reactome.org/PathwayBrowser/#/R-SSC-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Sus scrofa A0A287AJ15 R-SSC-1889978 https://reactome.org/PathwayBrowser/#/R-SSC-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Sus scrofa A0A287AJ15 R-SSC-1889981 https://reactome.org/PathwayBrowser/#/R-SSC-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Sus scrofa A0A287AJ15 R-SSC-2022851 https://reactome.org/PathwayBrowser/#/R-SSC-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Sus scrofa A0A287AJ15 R-SSC-2022856 https://reactome.org/PathwayBrowser/#/R-SSC-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Sus scrofa A0A287AJ15 R-SSC-2022860 https://reactome.org/PathwayBrowser/#/R-SSC-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Sus scrofa A0A287AJ15 R-SSC-2022887 https://reactome.org/PathwayBrowser/#/R-SSC-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Sus scrofa A0A287AJ15 R-SSC-2022919 https://reactome.org/PathwayBrowser/#/R-SSC-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Sus scrofa A0A287AJ15 R-SSC-2024084 https://reactome.org/PathwayBrowser/#/R-SSC-2024084 HS-GAGs translocate to the lysosome for degradation IEA Sus scrofa A0A287AJ15 R-SSC-2024108 https://reactome.org/PathwayBrowser/#/R-SSC-2024108 Some HSPGs are secreted to the plasma membrane IEA Sus scrofa A0A287AJ15 R-SSC-2076383 https://reactome.org/PathwayBrowser/#/R-SSC-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Sus scrofa A0A287AJ15 R-SSC-2076392 https://reactome.org/PathwayBrowser/#/R-SSC-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Sus scrofa A0A287AJ15 R-SSC-2076419 https://reactome.org/PathwayBrowser/#/R-SSC-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Sus scrofa A0A287AJ15 R-SSC-2076508 https://reactome.org/PathwayBrowser/#/R-SSC-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Sus scrofa A0A287AJ15 R-SSC-2076611 https://reactome.org/PathwayBrowser/#/R-SSC-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Sus scrofa A0A287AJ15 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa A0A287AJ15 R-SSC-2423785 https://reactome.org/PathwayBrowser/#/R-SSC-2423785 CR:atREs binds apoE and HSPG IEA Sus scrofa A0A287AJ15 R-SSC-5362427 https://reactome.org/PathwayBrowser/#/R-SSC-5362427 Hh-Np binds GPC5 IEA Sus scrofa A0A287AJ15 R-SSC-5362553 https://reactome.org/PathwayBrowser/#/R-SSC-5362553 NOTUM releases Hh-Np:GPC5 from the plasma membrane IEA Sus scrofa A0A287AJ15 R-SSC-9638064 https://reactome.org/PathwayBrowser/#/R-SSC-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Sus scrofa A0A287AJ16 R-SSC-5695957 https://reactome.org/PathwayBrowser/#/R-SSC-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Sus scrofa A0A287AJ30 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AJ30 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287AJ30 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AJ30 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AJ32 R-SSC-77068 https://reactome.org/PathwayBrowser/#/R-SSC-77068 Activation of GT IEA Sus scrofa A0A287AJ32 R-SSC-77069 https://reactome.org/PathwayBrowser/#/R-SSC-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Sus scrofa A0A287AJ32 R-SSC-77073 https://reactome.org/PathwayBrowser/#/R-SSC-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Sus scrofa A0A287AJ32 R-SSC-77077 https://reactome.org/PathwayBrowser/#/R-SSC-77077 Capping complex formation IEA Sus scrofa A0A287AJ32 R-SSC-77078 https://reactome.org/PathwayBrowser/#/R-SSC-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Sus scrofa A0A287AJ32 R-SSC-77081 https://reactome.org/PathwayBrowser/#/R-SSC-77081 Formation of the CE:GMP intermediate complex IEA Sus scrofa A0A287AJ32 R-SSC-77083 https://reactome.org/PathwayBrowser/#/R-SSC-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Sus scrofa A0A287AJ32 R-SSC-77085 https://reactome.org/PathwayBrowser/#/R-SSC-77085 Dissociation of transcript with 5'-GMP from GT IEA Sus scrofa A0A287AJ32 R-SSC-77090 https://reactome.org/PathwayBrowser/#/R-SSC-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Sus scrofa A0A287AJ47 R-SSC-5668414 https://reactome.org/PathwayBrowser/#/R-SSC-5668414 TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK IEA Sus scrofa A0A287AJ47 R-SSC-5668454 https://reactome.org/PathwayBrowser/#/R-SSC-5668454 K63polyUb-cIAP1,2 ubiquitinates TRAF3 IEA Sus scrofa A0A287AJ47 R-SSC-5668481 https://reactome.org/PathwayBrowser/#/R-SSC-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Sus scrofa A0A287AJ47 R-SSC-5668534 https://reactome.org/PathwayBrowser/#/R-SSC-5668534 cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK IEA Sus scrofa A0A287AJ47 R-SSC-5676596 https://reactome.org/PathwayBrowser/#/R-SSC-5676596 TRAF3 binds BAFFR:BAFF IEA Sus scrofa A0A287AJ47 R-SSC-5676599 https://reactome.org/PathwayBrowser/#/R-SSC-5676599 sBAFF trimer binds BAFFR IEA Sus scrofa A0A287AJ51 R-SSC-2022368 https://reactome.org/PathwayBrowser/#/R-SSC-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Sus scrofa A0A287AJ51 R-SSC-2022378 https://reactome.org/PathwayBrowser/#/R-SSC-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Sus scrofa A0A287AJ51 R-SSC-2022379 https://reactome.org/PathwayBrowser/#/R-SSC-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Sus scrofa A0A287AJ51 R-SSC-2022381 https://reactome.org/PathwayBrowser/#/R-SSC-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa A0A287AJ51 R-SSC-2022383 https://reactome.org/PathwayBrowser/#/R-SSC-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa A0A287AJ51 R-SSC-2022396 https://reactome.org/PathwayBrowser/#/R-SSC-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Sus scrofa A0A287AJ51 R-SSC-2022398 https://reactome.org/PathwayBrowser/#/R-SSC-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Sus scrofa A0A287AJ51 R-SSC-2022399 https://reactome.org/PathwayBrowser/#/R-SSC-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Sus scrofa A0A287AJ51 R-SSC-2022403 https://reactome.org/PathwayBrowser/#/R-SSC-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Sus scrofa A0A287AJ51 R-SSC-2022405 https://reactome.org/PathwayBrowser/#/R-SSC-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa A0A287AJ51 R-SSC-2022411 https://reactome.org/PathwayBrowser/#/R-SSC-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa A0A287AJ51 R-SSC-2022412 https://reactome.org/PathwayBrowser/#/R-SSC-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Sus scrofa A0A287AJ51 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa A0A287AJ51 R-SSC-2065357 https://reactome.org/PathwayBrowser/#/R-SSC-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Sus scrofa A0A287AJ51 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(34-41) binds to AGTR1 IEA Sus scrofa A0A287AJ51 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287AJ51 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287AJ51 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287AJ51 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287AJ51 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287AJ51 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287AJ51 R-SSC-9615348 https://reactome.org/PathwayBrowser/#/R-SSC-9615348 AGT(34-41) binds to AGTR2 IEA Sus scrofa A0A287AJ70 R-SSC-6801195 https://reactome.org/PathwayBrowser/#/R-SSC-6801195 STEAP3 binds BNIP3L IEA Sus scrofa A0A287AJ72 R-SSC-141423 https://reactome.org/PathwayBrowser/#/R-SSC-141423 Binding of the MCC complex to the APC/C complex IEA Sus scrofa A0A287AJ72 R-SSC-174057 https://reactome.org/PathwayBrowser/#/R-SSC-174057 Multiubiquitination of APC/C-associated Cdh1 IEA Sus scrofa A0A287AJ72 R-SSC-174058 https://reactome.org/PathwayBrowser/#/R-SSC-174058 Degradation of multiubiquitinated Cdh1 IEA Sus scrofa A0A287AJ72 R-SSC-174070 https://reactome.org/PathwayBrowser/#/R-SSC-174070 Association of Cdh1 with the APC/C IEA Sus scrofa A0A287AJ72 R-SSC-174079 https://reactome.org/PathwayBrowser/#/R-SSC-174079 Phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Sus scrofa A0A287AJ72 R-SSC-174088 https://reactome.org/PathwayBrowser/#/R-SSC-174088 Association of cell cycle proteins with the APC/C:Cdh1 complex IEA Sus scrofa A0A287AJ72 R-SSC-174104 https://reactome.org/PathwayBrowser/#/R-SSC-174104 Ubiquitination of Cyclin A by APC/C:Cdc20 complex IEA Sus scrofa A0A287AJ72 R-SSC-174105 https://reactome.org/PathwayBrowser/#/R-SSC-174105 Degradation of multiubiquitinated cell cycle proteins IEA Sus scrofa A0A287AJ72 R-SSC-174119 https://reactome.org/PathwayBrowser/#/R-SSC-174119 Free APC/C phosphorylated by Plk1 IEA Sus scrofa A0A287AJ72 R-SSC-174120 https://reactome.org/PathwayBrowser/#/R-SSC-174120 Association of Cyclin B:Cdc2 with Cdc20:APC/C complex IEA Sus scrofa A0A287AJ72 R-SSC-174121 https://reactome.org/PathwayBrowser/#/R-SSC-174121 Association of Securin with Cdc20:APC/C complex IEA Sus scrofa A0A287AJ72 R-SSC-174132 https://reactome.org/PathwayBrowser/#/R-SSC-174132 Free APC/C phosphorylated by Cyclin B:Cdc2 IEA Sus scrofa A0A287AJ72 R-SSC-174139 https://reactome.org/PathwayBrowser/#/R-SSC-174139 Dissociation of phospho-Cdh1 from the APC/C complex IEA Sus scrofa A0A287AJ72 R-SSC-174144 https://reactome.org/PathwayBrowser/#/R-SSC-174144 Ubiquitination of Securin by phospho-APC/C:Cdc20 complex IEA Sus scrofa A0A287AJ72 R-SSC-174157 https://reactome.org/PathwayBrowser/#/R-SSC-174157 Degradation of multiubiquitinated Cyclin B IEA Sus scrofa A0A287AJ72 R-SSC-174171 https://reactome.org/PathwayBrowser/#/R-SSC-174171 Association of Cyclin A with the APC/C IEA Sus scrofa A0A287AJ72 R-SSC-174195 https://reactome.org/PathwayBrowser/#/R-SSC-174195 Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex IEA Sus scrofa A0A287AJ72 R-SSC-174202 https://reactome.org/PathwayBrowser/#/R-SSC-174202 Degradation of multiubiquitinated Securin IEA Sus scrofa A0A287AJ72 R-SSC-174224 https://reactome.org/PathwayBrowser/#/R-SSC-174224 Dissociation of Cdc20 from APC/C complex IEA Sus scrofa A0A287AJ72 R-SSC-174227 https://reactome.org/PathwayBrowser/#/R-SSC-174227 Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex IEA Sus scrofa A0A287AJ72 R-SSC-174238 https://reactome.org/PathwayBrowser/#/R-SSC-174238 Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 IEA Sus scrofa A0A287AJ72 R-SSC-174255 https://reactome.org/PathwayBrowser/#/R-SSC-174255 Degradation multiubiquitinated Cyclin A IEA Sus scrofa A0A287AJ72 R-SSC-179417 https://reactome.org/PathwayBrowser/#/R-SSC-179417 Multiubiquitination of Nek2A IEA Sus scrofa A0A287AJ72 R-SSC-179421 https://reactome.org/PathwayBrowser/#/R-SSC-179421 Degradation of multiubiquitinated Nek2A IEA Sus scrofa A0A287AJ72 R-SSC-188191 https://reactome.org/PathwayBrowser/#/R-SSC-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Sus scrofa A0A287AJ72 R-SSC-188371 https://reactome.org/PathwayBrowser/#/R-SSC-188371 Association of Cyclin A:Cdk2 with Cdh1 IEA Sus scrofa A0A287AJ72 R-SSC-3788705 https://reactome.org/PathwayBrowser/#/R-SSC-3788705 CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 IEA Sus scrofa A0A287AJ72 R-SSC-3788708 https://reactome.org/PathwayBrowser/#/R-SSC-3788708 CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 IEA Sus scrofa A0A287AJ72 R-SSC-3788724 https://reactome.org/PathwayBrowser/#/R-SSC-3788724 Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 IEA Sus scrofa A0A287AJ72 R-SSC-3788725 https://reactome.org/PathwayBrowser/#/R-SSC-3788725 Cdh1:APC/C complex binds EHMT1:EHMT2 IEA Sus scrofa A0A287AJ72 R-SSC-68712 https://reactome.org/PathwayBrowser/#/R-SSC-68712 The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 IEA Sus scrofa A0A287AJ72 R-SSC-69015 https://reactome.org/PathwayBrowser/#/R-SSC-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Sus scrofa A0A287AJ72 R-SSC-9686969 https://reactome.org/PathwayBrowser/#/R-SSC-9686969 APC/C:Cdh1 polyubiquitinates SKP2 IEA Sus scrofa A0A287AJ72 R-SSC-9686980 https://reactome.org/PathwayBrowser/#/R-SSC-9686980 RB1 recruits APC/C:Cdh1 complex to SKP2 IEA Sus scrofa A0A287AJ72 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AJ72 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287AJ72 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AJ72 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AJ83 R-SSC-5624949 https://reactome.org/PathwayBrowser/#/R-SSC-5624949 Assembly of the anterograde IFT train IEA Sus scrofa A0A287AJ83 R-SSC-5624952 https://reactome.org/PathwayBrowser/#/R-SSC-5624952 Assembly of the retrograde IFT train IEA Sus scrofa A0A287AJ83 R-SSC-5625416 https://reactome.org/PathwayBrowser/#/R-SSC-5625416 Anterograde IFT IEA Sus scrofa A0A287AJ83 R-SSC-5625421 https://reactome.org/PathwayBrowser/#/R-SSC-5625421 The anterograde IFT train dissociates IEA Sus scrofa A0A287AJ83 R-SSC-5625424 https://reactome.org/PathwayBrowser/#/R-SSC-5625424 The retrograde IFT train dissociates IEA Sus scrofa A0A287AJ83 R-SSC-5625426 https://reactome.org/PathwayBrowser/#/R-SSC-5625426 Retrograde IFT IEA Sus scrofa A0A287AJ85 R-SSC-9770119 https://reactome.org/PathwayBrowser/#/R-SSC-9770119 Formation of the Spliceosomal E complex IEA Sus scrofa A0A287AJ98 R-SSC-111742 https://reactome.org/PathwayBrowser/#/R-SSC-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa A0A287AJ98 R-SSC-111751 https://reactome.org/PathwayBrowser/#/R-SSC-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa A0A287AJA2 R-SSC-6797554 https://reactome.org/PathwayBrowser/#/R-SSC-6797554 ABP1 binds SHANK proteins IEA Sus scrofa A0A287AJC7 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287AJD2 R-SSC-203797 https://reactome.org/PathwayBrowser/#/R-SSC-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Sus scrofa A0A287AJD2 R-SSC-5675376 https://reactome.org/PathwayBrowser/#/R-SSC-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Sus scrofa A0A287AJD5 R-SSC-114552 https://reactome.org/PathwayBrowser/#/R-SSC-114552 Thrombin-activated PARs activate G12/13 IEA Sus scrofa A0A287AJD5 R-SSC-397891 https://reactome.org/PathwayBrowser/#/R-SSC-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Sus scrofa A0A287AJD5 R-SSC-398184 https://reactome.org/PathwayBrowser/#/R-SSC-398184 LARG activation by G alpha 12/13 IEA Sus scrofa A0A287AJD5 R-SSC-398185 https://reactome.org/PathwayBrowser/#/R-SSC-398185 LARG binds plexin B1 IEA Sus scrofa A0A287AJD5 R-SSC-418574 https://reactome.org/PathwayBrowser/#/R-SSC-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Sus scrofa A0A287AJD5 R-SSC-751019 https://reactome.org/PathwayBrowser/#/R-SSC-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Sus scrofa A0A287AJD5 R-SSC-751027 https://reactome.org/PathwayBrowser/#/R-SSC-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Sus scrofa A0A287AJD5 R-SSC-751029 https://reactome.org/PathwayBrowser/#/R-SSC-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Sus scrofa A0A287AJD5 R-SSC-751039 https://reactome.org/PathwayBrowser/#/R-SSC-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Sus scrofa A0A287AJD5 R-SSC-8964246 https://reactome.org/PathwayBrowser/#/R-SSC-8964246 BTK in G alpha (12)-BTK complex is activated IEA Sus scrofa A0A287AJD5 R-SSC-8964274 https://reactome.org/PathwayBrowser/#/R-SSC-8964274 G alpha (12) binds BTK IEA Sus scrofa A0A287AJD5 R-SSC-8964333 https://reactome.org/PathwayBrowser/#/R-SSC-8964333 G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) IEA Sus scrofa A0A287AJD7 R-SSC-444120 https://reactome.org/PathwayBrowser/#/R-SSC-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Sus scrofa A0A287AJF9 R-SSC-5696482 https://reactome.org/PathwayBrowser/#/R-SSC-5696482 CTF1 binds LIFR:JAKs IEA Sus scrofa A0A287AJF9 R-SSC-6783524 https://reactome.org/PathwayBrowser/#/R-SSC-6783524 OSM,LIF,CTF1 receptor complex binds gp130 IEA Sus scrofa A0A287AJF9 R-SSC-6783552 https://reactome.org/PathwayBrowser/#/R-SSC-6783552 OSM binds LIFR:JAKs,OSMR:JAKs IEA Sus scrofa A0A287AJF9 R-SSC-6783556 https://reactome.org/PathwayBrowser/#/R-SSC-6783556 LIFR:JAKs bind gp130:JAKs:CNTFR IEA Sus scrofa A0A287AJF9 R-SSC-6783681 https://reactome.org/PathwayBrowser/#/R-SSC-6783681 LIF binds LIFR IEA Sus scrofa A0A287AJF9 R-SSC-6784189 https://reactome.org/PathwayBrowser/#/R-SSC-6784189 JAKs bind LIFR IEA Sus scrofa A0A287AJG7 R-SSC-1296127 https://reactome.org/PathwayBrowser/#/R-SSC-1296127 Activation of voltage gated Potassium channels IEA Sus scrofa A0A287AJG7 R-SSC-381713 https://reactome.org/PathwayBrowser/#/R-SSC-381713 Potassium voltage-gated channels close in reponse to PKA IEA Sus scrofa A0A287AJG8 R-SSC-997263 https://reactome.org/PathwayBrowser/#/R-SSC-997263 JMJD1C demethylates H3K9 mono- and di-methylation IEA Sus scrofa A0A287AJH7 R-SSC-1632857 https://reactome.org/PathwayBrowser/#/R-SSC-1632857 ULK1 phosphorylates AMBRA1:BECN1 complex IEA Sus scrofa A0A287AJH7 R-SSC-5665868 https://reactome.org/PathwayBrowser/#/R-SSC-5665868 AMPK (complex) phosphorylates ULK1 (complex) IEA Sus scrofa A0A287AJH7 R-SSC-5672008 https://reactome.org/PathwayBrowser/#/R-SSC-5672008 Thr-180 of ULK1 is phosphorylated IEA Sus scrofa A0A287AJH7 R-SSC-5672010 https://reactome.org/PathwayBrowser/#/R-SSC-5672010 Active MTORC1 phosphorylates ULK1 IEA Sus scrofa A0A287AJH7 R-SSC-5672011 https://reactome.org/PathwayBrowser/#/R-SSC-5672011 p-AMPK:AMP binds the ULK complex IEA Sus scrofa A0A287AJH7 R-SSC-5672817 https://reactome.org/PathwayBrowser/#/R-SSC-5672817 Active MTORC1 binds the ULK1 complex IEA Sus scrofa A0A287AJH7 R-SSC-5673768 https://reactome.org/PathwayBrowser/#/R-SSC-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Sus scrofa A0A287AJH7 R-SSC-5675790 https://reactome.org/PathwayBrowser/#/R-SSC-5675790 MTORC1 dissociates from ULK complex IEA Sus scrofa A0A287AJH7 R-SSC-5675868 https://reactome.org/PathwayBrowser/#/R-SSC-5675868 ULK1 phosphorylates ATG13 and RB1CC1 IEA Sus scrofa A0A287AJH7 R-SSC-5679205 https://reactome.org/PathwayBrowser/#/R-SSC-5679205 ULK1 phosphorylates Beclin-1 IEA Sus scrofa A0A287AJH7 R-SSC-5679239 https://reactome.org/PathwayBrowser/#/R-SSC-5679239 ULK complex translocates to the ER IEA Sus scrofa A0A287AJH7 R-SSC-5683925 https://reactome.org/PathwayBrowser/#/R-SSC-5683925 ULK1 is dephosphorylated IEA Sus scrofa A0A287AJK0 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A287AJK0 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A287AJK0 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A287AJK0 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A287AJK0 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A287AJK0 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A287AJK0 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A287AJK0 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A287AJK0 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A287AJK0 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287AJK0 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A287AJK0 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A287AJK0 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287AJK0 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A287AJK0 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287AJK0 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287AJK0 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287AJK0 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287AJK0 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287AJK0 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A287AJK0 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A287AJK4 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287AJK6 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A287AJK6 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A287AJK6 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A287AJK6 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A287AJK6 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A287AJL4 R-SSC-6781897 https://reactome.org/PathwayBrowser/#/R-SSC-6781897 USP11 deubiquitinates NFKBIA IEA Sus scrofa A0A287AJL6 R-SSC-199895 https://reactome.org/PathwayBrowser/#/R-SSC-199895 RSK1/2/3 phosphorylates CREB at Serine 119 IEA Sus scrofa A0A287AJL6 R-SSC-199917 https://reactome.org/PathwayBrowser/#/R-SSC-199917 MAPKAPK2 phosphorylates CREB at Serine 133 IEA Sus scrofa A0A287AJL6 R-SSC-199935 https://reactome.org/PathwayBrowser/#/R-SSC-199935 MSK1 activates CREB IEA Sus scrofa A0A287AJL6 R-SSC-442724 https://reactome.org/PathwayBrowser/#/R-SSC-442724 Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) IEA Sus scrofa A0A287AJL6 R-SSC-9612501 https://reactome.org/PathwayBrowser/#/R-SSC-9612501 SGK phosphorylates CREB1 IEA Sus scrofa A0A287AJM8 R-SSC-8940641 https://reactome.org/PathwayBrowser/#/R-SSC-8940641 THOP1 cleaves oligopeptide fragment (8-16aa) IEA Sus scrofa A0A287AJN5 R-SSC-1592240 https://reactome.org/PathwayBrowser/#/R-SSC-1592240 Formation of NRF2 IEA Sus scrofa A0A287AJP5 R-SSC-203973 https://reactome.org/PathwayBrowser/#/R-SSC-203973 Vesicle budding IEA Sus scrofa A0A287AJP5 R-SSC-204008 https://reactome.org/PathwayBrowser/#/R-SSC-204008 SEC31:SEC13 and v-SNARE recruitment IEA Sus scrofa A0A287AJP5 R-SSC-5694409 https://reactome.org/PathwayBrowser/#/R-SSC-5694409 Nucleotide exchange on RAB1 IEA Sus scrofa A0A287AJP5 R-SSC-5694418 https://reactome.org/PathwayBrowser/#/R-SSC-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Sus scrofa A0A287AJP5 R-SSC-5694423 https://reactome.org/PathwayBrowser/#/R-SSC-5694423 NSF and SNAPs bind cis-SNARE complex IEA Sus scrofa A0A287AJP5 R-SSC-5694425 https://reactome.org/PathwayBrowser/#/R-SSC-5694425 NSF ATPase activity dissociates cis-SNARE IEA Sus scrofa A0A287AJP5 R-SSC-5694446 https://reactome.org/PathwayBrowser/#/R-SSC-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Sus scrofa A0A287AJQ2 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A287AJQ2 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287AJQ2 R-SSC-71445 https://reactome.org/PathwayBrowser/#/R-SSC-71445 PGAM dimers isomerise 2PG to 3PG IEA Sus scrofa A0A287AJQ2 R-SSC-71654 https://reactome.org/PathwayBrowser/#/R-SSC-71654 PGAM dimers isomerise 3PG to 2PG IEA Sus scrofa A0A287AJQ6 R-SSC-1504186 https://reactome.org/PathwayBrowser/#/R-SSC-1504186 DVL recruits GSK3beta:AXIN1 to the receptor complex IEA Sus scrofa A0A287AJQ6 R-SSC-1504190 https://reactome.org/PathwayBrowser/#/R-SSC-1504190 DVL is ubiquitinated by CUL3:KLHL12:RBX1 IEA Sus scrofa A0A287AJQ6 R-SSC-1504193 https://reactome.org/PathwayBrowser/#/R-SSC-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Sus scrofa A0A287AJQ6 R-SSC-1504213 https://reactome.org/PathwayBrowser/#/R-SSC-1504213 DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex IEA Sus scrofa A0A287AJQ6 R-SSC-201677 https://reactome.org/PathwayBrowser/#/R-SSC-201677 Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta IEA Sus scrofa A0A287AJQ6 R-SSC-201685 https://reactome.org/PathwayBrowser/#/R-SSC-201685 Beta-catenin is released from the destruction complex IEA Sus scrofa A0A287AJQ6 R-SSC-201717 https://reactome.org/PathwayBrowser/#/R-SSC-201717 CSNK2-mediated phosphorylation of DVL IEA Sus scrofa A0A287AJQ6 R-SSC-2066299 https://reactome.org/PathwayBrowser/#/R-SSC-2066299 DVL2 binds phosphorylated WWTR1 (TAZ) IEA Sus scrofa A0A287AJQ6 R-SSC-3772434 https://reactome.org/PathwayBrowser/#/R-SSC-3772434 Phosphorylated DVL recruits PIP5K1B to the plasma membrane IEA Sus scrofa A0A287AJQ6 R-SSC-3772435 https://reactome.org/PathwayBrowser/#/R-SSC-3772435 WNT signaling stimulates CSNK1-dependent phosphorylation of DVL IEA Sus scrofa A0A287AJQ6 R-SSC-3772436 https://reactome.org/PathwayBrowser/#/R-SSC-3772436 DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 IEA Sus scrofa A0A287AJQ6 R-SSC-3858475 https://reactome.org/PathwayBrowser/#/R-SSC-3858475 ppDVL recruits RAC IEA Sus scrofa A0A287AJQ6 R-SSC-3858482 https://reactome.org/PathwayBrowser/#/R-SSC-3858482 DVL is recruited to the receptor IEA Sus scrofa A0A287AJQ6 R-SSC-3858489 https://reactome.org/PathwayBrowser/#/R-SSC-3858489 ppDVL binds DAAM1 IEA Sus scrofa A0A287AJQ6 R-SSC-3858495 https://reactome.org/PathwayBrowser/#/R-SSC-3858495 DAAM1 recruits GTP-bound RHOA IEA Sus scrofa A0A287AJQ6 R-SSC-3965450 https://reactome.org/PathwayBrowser/#/R-SSC-3965450 DAAM1 recruits PFN1 IEA Sus scrofa A0A287AJQ6 R-SSC-4608852 https://reactome.org/PathwayBrowser/#/R-SSC-4608852 SMURF1/2 ubiquitinates PRICKLE1 IEA Sus scrofa A0A287AJQ6 R-SSC-4608854 https://reactome.org/PathwayBrowser/#/R-SSC-4608854 SMURF1/2 are recruited to the DVL2:PARD6A complex IEA Sus scrofa A0A287AJQ6 R-SSC-4641147 https://reactome.org/PathwayBrowser/#/R-SSC-4641147 DACT1 binds DVL2 IEA Sus scrofa A0A287AJQ6 R-SSC-5138432 https://reactome.org/PathwayBrowser/#/R-SSC-5138432 DVL2 is phosphorylated by PKC IEA Sus scrofa A0A287AJQ6 R-SSC-5138433 https://reactome.org/PathwayBrowser/#/R-SSC-5138433 p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis IEA Sus scrofa A0A287AJQ6 R-SSC-5138441 https://reactome.org/PathwayBrowser/#/R-SSC-5138441 WNT5A-FZD4 recruits DVL2 IEA Sus scrofa A0A287AJQ6 R-SSC-5138459 https://reactome.org/PathwayBrowser/#/R-SSC-5138459 WNT5A:FZD4 is endocytosed IEA Sus scrofa A0A287AJQ6 R-SSC-8866269 https://reactome.org/PathwayBrowser/#/R-SSC-8866269 ARRB bind GPCRs IEA Sus scrofa A0A287AJQ6 R-SSC-8866283 https://reactome.org/PathwayBrowser/#/R-SSC-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Sus scrofa A0A287AJQ6 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A287AJQ6 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A287AJQ6 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A287AJQ6 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A287AJQ6 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A287AJQ6 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287AJQ6 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287AJQ6 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287AJQ6 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287AJQ6 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287AJQ6 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287AJQ6 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287AJQ6 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287AJQ6 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287AJS0 R-SSC-114544 https://reactome.org/PathwayBrowser/#/R-SSC-114544 p115-RhoGEF activation of RHOA IEA Sus scrofa A0A287AJS0 R-SSC-114548 https://reactome.org/PathwayBrowser/#/R-SSC-114548 G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) IEA Sus scrofa A0A287AJS0 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa A0A287AJS0 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa A0A287AJS0 R-SSC-8980691 https://reactome.org/PathwayBrowser/#/R-SSC-8980691 RHOA GEFs activate RHOA IEA Sus scrofa A0A287AJS0 R-SSC-9013023 https://reactome.org/PathwayBrowser/#/R-SSC-9013023 RHOB GEFs activate RHOB IEA Sus scrofa A0A287AJS0 R-SSC-9013109 https://reactome.org/PathwayBrowser/#/R-SSC-9013109 RHOC GEFs activate RHOC IEA Sus scrofa A0A287AJS8 R-SSC-1236943 https://reactome.org/PathwayBrowser/#/R-SSC-1236943 Loading of antigen peptide onto MHC class I molecule IEA Sus scrofa A0A287AJS8 R-SSC-1236954 https://reactome.org/PathwayBrowser/#/R-SSC-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Sus scrofa A0A287AJS8 R-SSC-1236964 https://reactome.org/PathwayBrowser/#/R-SSC-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Sus scrofa A0A287AJS8 R-SSC-1236965 https://reactome.org/PathwayBrowser/#/R-SSC-1236965 Export of peptide loaded MHC class I complex to PM IEA Sus scrofa A0A287AJS8 R-SSC-198955 https://reactome.org/PathwayBrowser/#/R-SSC-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Sus scrofa A0A287AJS8 R-SSC-198958 https://reactome.org/PathwayBrowser/#/R-SSC-198958 KIR2DL2/3 interacting with HLA-C group 1 (Cw4) IEA Sus scrofa A0A287AJS8 R-SSC-199558 https://reactome.org/PathwayBrowser/#/R-SSC-199558 KIR2DL1 interacting with HLA-C group 2 (Cw3) IEA Sus scrofa A0A287AJS8 R-SSC-199566 https://reactome.org/PathwayBrowser/#/R-SSC-199566 KIR3DL1 interacting with HLA Bw4 IEA Sus scrofa A0A287AJS8 R-SSC-199583 https://reactome.org/PathwayBrowser/#/R-SSC-199583 KIR2DS2 interacting with HLA-C group 1 (Cw3) IEA Sus scrofa A0A287AJS8 R-SSC-199587 https://reactome.org/PathwayBrowser/#/R-SSC-199587 KIR2DS1 interacting with HLA-C group 2 (Cw4) IEA Sus scrofa A0A287AJS8 R-SSC-210298 https://reactome.org/PathwayBrowser/#/R-SSC-210298 Interaction of DAP12 and KIR3DS1 IEA Sus scrofa A0A287AJS8 R-SSC-210309 https://reactome.org/PathwayBrowser/#/R-SSC-210309 Interaction of DAP12 and KIR2DS2 IEA Sus scrofa A0A287AJS8 R-SSC-2272753 https://reactome.org/PathwayBrowser/#/R-SSC-2272753 Interaction of DAP12 and KIR2DS4 IEA Sus scrofa A0A287AJS8 R-SSC-2272795 https://reactome.org/PathwayBrowser/#/R-SSC-2272795 Interaction of DAP12 and KIR2DS1 IEA Sus scrofa A0A287AJS8 R-SSC-6798739 https://reactome.org/PathwayBrowser/#/R-SSC-6798739 Exocytosis of azurophil granule membrane proteins IEA Sus scrofa A0A287AJS8 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A287AJS8 R-SSC-8863973 https://reactome.org/PathwayBrowser/#/R-SSC-8863973 Fusion of ERC and phagosome IEA Sus scrofa A0A287AJS8 R-SSC-8951499 https://reactome.org/PathwayBrowser/#/R-SSC-8951499 Loading of antigenic peptides on to class I MHC IEA Sus scrofa A0A287AJS8 R-SSC-983138 https://reactome.org/PathwayBrowser/#/R-SSC-983138 Transport of MHC heterotrimer to ER exit site IEA Sus scrofa A0A287AJS8 R-SSC-983142 https://reactome.org/PathwayBrowser/#/R-SSC-983142 Formation of peptide loading complex (PLC) IEA Sus scrofa A0A287AJS8 R-SSC-983145 https://reactome.org/PathwayBrowser/#/R-SSC-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Sus scrofa A0A287AJS8 R-SSC-983146 https://reactome.org/PathwayBrowser/#/R-SSC-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Sus scrofa A0A287AJS8 R-SSC-983161 https://reactome.org/PathwayBrowser/#/R-SSC-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex IEA Sus scrofa A0A287AJS8 R-SSC-983421 https://reactome.org/PathwayBrowser/#/R-SSC-983421 Journey of cargo through Golgi complex IEA Sus scrofa A0A287AJS8 R-SSC-983422 https://reactome.org/PathwayBrowser/#/R-SSC-983422 Disassembly of COPII coated vesicle IEA Sus scrofa A0A287AJS8 R-SSC-983424 https://reactome.org/PathwayBrowser/#/R-SSC-983424 Budding of COPII coated vesicle IEA Sus scrofa A0A287AJS8 R-SSC-983425 https://reactome.org/PathwayBrowser/#/R-SSC-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Sus scrofa A0A287AJS8 R-SSC-983427 https://reactome.org/PathwayBrowser/#/R-SSC-983427 Expression of peptide bound class I MHC on cell surface IEA Sus scrofa A0A287AJT7 R-SSC-156826 https://reactome.org/PathwayBrowser/#/R-SSC-156826 Dissociation of L13a from the 60s ribosomal subunit IEA Sus scrofa A0A287AJT7 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A287AJT7 R-SSC-6791218 https://reactome.org/PathwayBrowser/#/R-SSC-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Sus scrofa A0A287AJT7 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A287AJT7 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A287AJT7 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A287AJT7 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A287AJT7 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A287AJT7 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A287AJT7 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A287AJT7 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A287AJU1 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A287AJU1 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287AJU3 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287AJU3 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287AJU3 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287AJU3 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287AJU3 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287AJU3 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287AJU5 R-SSC-8854329 https://reactome.org/PathwayBrowser/#/R-SSC-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Sus scrofa A0A287AJU5 R-SSC-8877451 https://reactome.org/PathwayBrowser/#/R-SSC-8877451 MON1:CCZ1 exchanges GTP for GDP on RAB7 IEA Sus scrofa A0A287AJV0 R-SSC-425678 https://reactome.org/PathwayBrowser/#/R-SSC-425678 SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ IEA Sus scrofa A0A287AJW4 R-SSC-8952631 https://reactome.org/PathwayBrowser/#/R-SSC-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AJW4 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287AJW4 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AJW4 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AJW4 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AJW4 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287AJW4 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AJW4 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AJX4 R-SSC-211873 https://reactome.org/PathwayBrowser/#/R-SSC-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Sus scrofa A0A287AJX4 R-SSC-211924 https://reactome.org/PathwayBrowser/#/R-SSC-211924 CYP4B1 12-hydroxylates ARA IEA Sus scrofa A0A287AJX4 R-SSC-211962 https://reactome.org/PathwayBrowser/#/R-SSC-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Sus scrofa A0A287AJX4 R-SSC-215526 https://reactome.org/PathwayBrowser/#/R-SSC-215526 CYP4F3 20-hydroxylates LTB4 IEA Sus scrofa A0A287AJX4 R-SSC-2161745 https://reactome.org/PathwayBrowser/#/R-SSC-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Sus scrofa A0A287AJX4 R-SSC-2161792 https://reactome.org/PathwayBrowser/#/R-SSC-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Sus scrofa A0A287AJX4 R-SSC-76466 https://reactome.org/PathwayBrowser/#/R-SSC-76466 CYP4A11 12-hydroxylates DDCX IEA Sus scrofa A0A287AJX7 R-SSC-72103 https://reactome.org/PathwayBrowser/#/R-SSC-72103 Formation of pre-mRNPs IEA Sus scrofa A0A287AJX7 R-SSC-9770119 https://reactome.org/PathwayBrowser/#/R-SSC-9770119 Formation of the Spliceosomal E complex IEA Sus scrofa A0A287AJX7 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A287AJX7 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287AJX7 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A287AJX7 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A287AJY4 R-SSC-2029465 https://reactome.org/PathwayBrowser/#/R-SSC-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Sus scrofa A0A287AJY4 R-SSC-2029466 https://reactome.org/PathwayBrowser/#/R-SSC-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Sus scrofa A0A287AJY4 R-SSC-2029469 https://reactome.org/PathwayBrowser/#/R-SSC-2029469 p-ERK phosphorylates WAVEs and ABI IEA Sus scrofa A0A287AJY4 R-SSC-2130194 https://reactome.org/PathwayBrowser/#/R-SSC-2130194 ABL phosphorylates WAVEs IEA Sus scrofa A0A287AJY4 R-SSC-2197690 https://reactome.org/PathwayBrowser/#/R-SSC-2197690 Detachment of WASP/WAVE IEA Sus scrofa A0A287AJY4 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A287AJY4 R-SSC-9014294 https://reactome.org/PathwayBrowser/#/R-SSC-9014294 RAC2 binds effectors at the plasma membrane IEA Sus scrofa A0A287AJY4 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa A0A287AJZ4 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AJZ4 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287AJZ4 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AJZ4 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AJZ4 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AJZ4 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AJZ4 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287AJZ4 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AJZ4 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AK10 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A287AK10 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A287AK10 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A287AK10 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A287AK10 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287AK10 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287AK10 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287AK10 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287AK10 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287AK10 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287AK10 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A287AK10 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A287AK10 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A287AK10 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A287AK10 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A287AK10 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A287AK10 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A287AK10 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A287AK10 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A287AK10 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A287AK10 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287AK10 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A287AK10 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A287AK10 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287AK10 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A287AK10 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287AK10 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287AK10 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287AK10 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287AK10 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287AK10 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A287AK10 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A287AK10 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A287AK10 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A287AK10 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A287AK10 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287AK36 R-SSC-9865350 https://reactome.org/PathwayBrowser/#/R-SSC-9865350 Nascent MT-CO1 binds to MITRAC, Mg2+, PE, CL IEA Sus scrofa A0A287AK36 R-SSC-9865412 https://reactome.org/PathwayBrowser/#/R-SSC-9865412 TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC IEA Sus scrofa A0A287AK36 R-SSC-9865449 https://reactome.org/PathwayBrowser/#/R-SSC-9865449 Metallochaperone inserts Cu2+ into MT-CO1 IEA Sus scrofa A0A287AK36 R-SSC-9865579 https://reactome.org/PathwayBrowser/#/R-SSC-9865579 MT-CO1 and MT-CO2 complexes associate, installing heme moieties IEA Sus scrofa A0A287AK36 R-SSC-9865663 https://reactome.org/PathwayBrowser/#/R-SSC-9865663 MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex IEA Sus scrofa A0A287AK49 R-SSC-2671885 https://reactome.org/PathwayBrowser/#/R-SSC-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Sus scrofa A0A287AK56 R-SSC-5681980 https://reactome.org/PathwayBrowser/#/R-SSC-5681980 ATG12 binds ATG7 dimer IEA Sus scrofa A0A287AK56 R-SSC-5681981 https://reactome.org/PathwayBrowser/#/R-SSC-5681981 ATG3 transfers LC3 from ATG7 to ATG3 IEA Sus scrofa A0A287AK56 R-SSC-5682011 https://reactome.org/PathwayBrowser/#/R-SSC-5682011 LC3 binds ATG7 dimer IEA Sus scrofa A0A287AK56 R-SSC-5682896 https://reactome.org/PathwayBrowser/#/R-SSC-5682896 LC3:ATG7 dimer binds ATG3 IEA Sus scrofa A0A287AK56 R-SSC-5683593 https://reactome.org/PathwayBrowser/#/R-SSC-5683593 ATG7:ATG3:LC3 dissociates IEA Sus scrofa A0A287AK56 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A287AK56 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287AK56 R-SSC-9020616 https://reactome.org/PathwayBrowser/#/R-SSC-9020616 ATG12 forms a thioester bond with ATG7 dimer IEA Sus scrofa A0A287AK56 R-SSC-983152 https://reactome.org/PathwayBrowser/#/R-SSC-983152 Transfer of ubiquitin from E1 to E2 IEA Sus scrofa A0A287AK56 R-SSC-983153 https://reactome.org/PathwayBrowser/#/R-SSC-983153 E1 mediated ubiquitin activation IEA Sus scrofa A0A287AK84 R-SSC-201603 https://reactome.org/PathwayBrowser/#/R-SSC-201603 Caspase-mediated cleavage of PKC theta IEA Sus scrofa A0A287AK84 R-SSC-202222 https://reactome.org/PathwayBrowser/#/R-SSC-202222 Phosphorylation of PKC theta IEA Sus scrofa A0A287AK84 R-SSC-202307 https://reactome.org/PathwayBrowser/#/R-SSC-202307 Change of PKC theta conformation IEA Sus scrofa A0A287AK84 R-SSC-202328 https://reactome.org/PathwayBrowser/#/R-SSC-202328 Translocation of PKC theta to plasma membrane IEA Sus scrofa A0A287AK84 R-SSC-202437 https://reactome.org/PathwayBrowser/#/R-SSC-202437 Phosphorylation of CARMA1 IEA Sus scrofa A0A287AK84 R-SSC-2730835 https://reactome.org/PathwayBrowser/#/R-SSC-2730835 Autophosphorylation of PKC-theta IEA Sus scrofa A0A287AK84 R-SSC-2730861 https://reactome.org/PathwayBrowser/#/R-SSC-2730861 Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 IEA Sus scrofa A0A287AK84 R-SSC-2730863 https://reactome.org/PathwayBrowser/#/R-SSC-2730863 Phosphorylation of CARMA1 by PKC-theta IEA Sus scrofa A0A287AK84 R-SSC-2730864 https://reactome.org/PathwayBrowser/#/R-SSC-2730864 Recruitment of TRAF6 to CBM complex by binding to MALT1 IEA Sus scrofa A0A287AK84 R-SSC-2730876 https://reactome.org/PathwayBrowser/#/R-SSC-2730876 Phosphorylation of IKK-beta by TAK1 IEA Sus scrofa A0A287AK84 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287AK84 R-SSC-2730899 https://reactome.org/PathwayBrowser/#/R-SSC-2730899 Oligomerization of BCL10 and MALT1 IEA Sus scrofa A0A287AK84 R-SSC-2730900 https://reactome.org/PathwayBrowser/#/R-SSC-2730900 Activation of TAK1 complex bound to pUb-TRAF6 IEA Sus scrofa A0A287AK84 R-SSC-2730902 https://reactome.org/PathwayBrowser/#/R-SSC-2730902 Oligomerization of p-CARMA1 IEA Sus scrofa A0A287AK84 R-SSC-2730903 https://reactome.org/PathwayBrowser/#/R-SSC-2730903 Oligomerization of TRAF6 IEA Sus scrofa A0A287AK84 R-SSC-2730904 https://reactome.org/PathwayBrowser/#/R-SSC-2730904 Auto-ubiquitination of TRAF6 IEA Sus scrofa A0A287AK84 R-SSC-374664 https://reactome.org/PathwayBrowser/#/R-SSC-374664 Phosphorylation and activation of Ezrin IEA Sus scrofa A0A287AK84 R-SSC-425861 https://reactome.org/PathwayBrowser/#/R-SSC-425861 Activation of Protein Kinase C novel isoforms IEA Sus scrofa A0A287AK84 R-SSC-9653503 https://reactome.org/PathwayBrowser/#/R-SSC-9653503 KRAS4B is phosphorylated on serine 181 IEA Sus scrofa A0A287AK86 R-SSC-199050 https://reactome.org/PathwayBrowser/#/R-SSC-199050 ICAM1-5 bind Integrin alphaLbeta2 (LFA-1) IEA Sus scrofa A0A287AK86 R-SSC-202704 https://reactome.org/PathwayBrowser/#/R-SSC-202704 Integrin alphaXbeta2 binds JAM3 IEA Sus scrofa A0A287AK86 R-SSC-202718 https://reactome.org/PathwayBrowser/#/R-SSC-202718 Integrin alphaLbeta2 (LFA-1) binds F11R (JAM-A) IEA Sus scrofa A0A287AK86 R-SSC-202727 https://reactome.org/PathwayBrowser/#/R-SSC-202727 Integrin alphaMbeta2 (MAC1) binds JAM3 IEA Sus scrofa A0A287AK86 R-SSC-216069 https://reactome.org/PathwayBrowser/#/R-SSC-216069 Interaction of integrin alphaDbeta2 with fibrin IEA Sus scrofa A0A287AK86 R-SSC-216082 https://reactome.org/PathwayBrowser/#/R-SSC-216082 Interaction of integrin alphaXbeta2 with fibrin IEA Sus scrofa A0A287AK86 R-SSC-2559439 https://reactome.org/PathwayBrowser/#/R-SSC-2559439 CD14:LPS binds CR3 IEA Sus scrofa A0A287AK86 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A287AK86 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A287AK86 R-SSC-6800426 https://reactome.org/PathwayBrowser/#/R-SSC-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Sus scrofa A0A287AK92 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A287AK92 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A287AK92 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A287AK92 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A287AK92 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A287AK92 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A287AK92 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A287AK92 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A287AK92 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A287AK92 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287AK92 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A287AK92 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A287AK92 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287AK92 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A287AK92 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287AK92 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287AK92 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287AK92 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287AK92 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287AK92 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A287AK92 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A287AKA2 R-SSC-9825759 https://reactome.org/PathwayBrowser/#/R-SSC-9825759 MAPK-dependent phosphorylation of KARS IEA Sus scrofa A0A287AKB2 R-SSC-6781953 https://reactome.org/PathwayBrowser/#/R-SSC-6781953 YOD1 binds VCP IEA Sus scrofa A0A287AKC0 R-SSC-156808 https://reactome.org/PathwayBrowser/#/R-SSC-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Sus scrofa A0A287AKC0 R-SSC-156823 https://reactome.org/PathwayBrowser/#/R-SSC-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Sus scrofa A0A287AKC0 R-SSC-157849 https://reactome.org/PathwayBrowser/#/R-SSC-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Sus scrofa A0A287AKC0 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A287AKC0 R-SSC-6791221 https://reactome.org/PathwayBrowser/#/R-SSC-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA IEA Sus scrofa A0A287AKC0 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa A0A287AKC0 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A287AKC0 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A287AKC0 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A287AKC0 R-SSC-72676 https://reactome.org/PathwayBrowser/#/R-SSC-72676 eIF3 and eIF1A bind to the 40S subunit IEA Sus scrofa A0A287AKC0 R-SSC-72691 https://reactome.org/PathwayBrowser/#/R-SSC-72691 Formation of the 43S pre-initiation complex IEA Sus scrofa A0A287AKC0 R-SSC-72697 https://reactome.org/PathwayBrowser/#/R-SSC-72697 Start codon recognition IEA Sus scrofa A0A287AKC0 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A287AKC0 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A287AKC0 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A287AKC0 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A287AKC0 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A287AKC1 R-SSC-1602466 https://reactome.org/PathwayBrowser/#/R-SSC-1602466 Activation of MT-MMPs by FURIN IEA Sus scrofa A0A287AKC1 R-SSC-1604360 https://reactome.org/PathwayBrowser/#/R-SSC-1604360 Initial activation of proMMP2 by MMP14 IEA Sus scrofa A0A287AKC1 R-SSC-1604741 https://reactome.org/PathwayBrowser/#/R-SSC-1604741 Initial activation of proMMP13 by MMP14 (MT1-MMP) IEA Sus scrofa A0A287AKC1 R-SSC-1605825 https://reactome.org/PathwayBrowser/#/R-SSC-1605825 MT-MMPs are sorted to the plasma membrane IEA Sus scrofa A0A287AKC1 R-SSC-9839367 https://reactome.org/PathwayBrowser/#/R-SSC-9839367 TGFBR3_mem cleavage by MMPs IEA Sus scrofa A0A287AKC2 R-SSC-2002440 https://reactome.org/PathwayBrowser/#/R-SSC-2002440 Removal of fibrillar collagen C-propeptides IEA Sus scrofa A0A287AKC2 R-SSC-2022141 https://reactome.org/PathwayBrowser/#/R-SSC-2022141 Prolysyl oxidase activation IEA Sus scrofa A0A287AKC2 R-SSC-2214330 https://reactome.org/PathwayBrowser/#/R-SSC-2214330 Cleavage of collagen VII NC2 region by BMP1 IEA Sus scrofa A0A287AKD0 R-SSC-212352 https://reactome.org/PathwayBrowser/#/R-SSC-212352 Formation of ARC coactivator complex IEA Sus scrofa A0A287AKG3 R-SSC-212252 https://reactome.org/PathwayBrowser/#/R-SSC-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Sus scrofa A0A287AKG3 R-SSC-212263 https://reactome.org/PathwayBrowser/#/R-SSC-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Sus scrofa A0A287AKJ4 R-SSC-1011598 https://reactome.org/PathwayBrowser/#/R-SSC-1011598 DOCKs bind to RhoGEFs IEA Sus scrofa A0A287AKJ4 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A287AKJ4 R-SSC-9014296 https://reactome.org/PathwayBrowser/#/R-SSC-9014296 RAC2 GEFs activate RAC2 IEA Sus scrofa A0A287AKJ4 R-SSC-9014449 https://reactome.org/PathwayBrowser/#/R-SSC-9014449 RHOG binds effectors at the plasma membrane IEA Sus scrofa A0A287AKJ4 R-SSC-9032798 https://reactome.org/PathwayBrowser/#/R-SSC-9032798 DOCK3 activates RAC1 IEA Sus scrofa A0A287AKL1 R-SSC-8869606 https://reactome.org/PathwayBrowser/#/R-SSC-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Sus scrofa A0A287AKL1 R-SSC-8869633 https://reactome.org/PathwayBrowser/#/R-SSC-8869633 NMRK1 phosphorylates NR to yield NMN IEA Sus scrofa A0A287AKM8 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A287AKQ9 R-SSC-1675795 https://reactome.org/PathwayBrowser/#/R-SSC-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Sus scrofa A0A287AKQ9 R-SSC-1676065 https://reactome.org/PathwayBrowser/#/R-SSC-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Sus scrofa A0A287AKR1 R-SSC-5696600 https://reactome.org/PathwayBrowser/#/R-SSC-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Sus scrofa A0A287AKS6 R-SSC-482770 https://reactome.org/PathwayBrowser/#/R-SSC-482770 Release of platelet secretory granule components IEA Sus scrofa A0A287AKS6 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A287AKU3 R-SSC-375140 https://reactome.org/PathwayBrowser/#/R-SSC-375140 CDO binds promyogenic cadherins IEA Sus scrofa A0A287AKU3 R-SSC-419001 https://reactome.org/PathwayBrowser/#/R-SSC-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Sus scrofa A0A287AKU3 R-SSC-419002 https://reactome.org/PathwayBrowser/#/R-SSC-419002 Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin IEA Sus scrofa A0A287AKU3 R-SSC-448958 https://reactome.org/PathwayBrowser/#/R-SSC-448958 Nuclear translocation of p38 MAPK IEA Sus scrofa A0A287AKW2 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287AKW2 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287AKW2 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287AKW2 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287AKW2 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287AKW2 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287AKW2 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287AKW2 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287AKW2 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287AKW2 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AKW2 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287AKW2 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287AKW2 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287AKW2 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287AKW2 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287AKW2 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287AKW2 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287AKW2 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287AKW2 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287AKW2 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287AKW2 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287AKW2 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287AKW2 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287AKW2 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287AKW2 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287AKW2 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287AKW2 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287AKW2 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287AKW2 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287AKW2 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287AKW2 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287AKW2 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287AKW2 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287AKW2 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287AKW2 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287AKW2 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287AKW2 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287AKW2 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287AKW2 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287AKW2 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287AKW2 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287AKW2 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287AKW2 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287AKW2 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287AKW2 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287AKW2 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287AKW2 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287AKW8 R-SSC-72670 https://reactome.org/PathwayBrowser/#/R-SSC-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Sus scrofa A0A287AKW8 R-SSC-72722 https://reactome.org/PathwayBrowser/#/R-SSC-72722 eIF2 activation IEA Sus scrofa A0A287AKY1 R-SSC-111925 https://reactome.org/PathwayBrowser/#/R-SSC-111925 cAMP induces dissociation of inactive PKA tetramers IEA Sus scrofa A0A287AKY1 R-SSC-5610749 https://reactome.org/PathwayBrowser/#/R-SSC-5610749 cAMP dissociates PKA, promoting GLI processing IEA Sus scrofa A0A287AKY1 R-SSC-8951727 https://reactome.org/PathwayBrowser/#/R-SSC-8951727 cAMP binds PKA tetramer IEA Sus scrofa A0A287AKY1 R-SSC-992708 https://reactome.org/PathwayBrowser/#/R-SSC-992708 Dual-specific AKAPs bind type I and II PKA regulatory subunits IEA Sus scrofa A0A287AKY5 R-SSC-418456 https://reactome.org/PathwayBrowser/#/R-SSC-418456 cGMP is degraded by PDEs IEA Sus scrofa A0A287AKY5 R-SSC-418553 https://reactome.org/PathwayBrowser/#/R-SSC-418553 cAMP degradation by Phosphodiesterases IEA Sus scrofa A0A287AKZ6 R-SSC-9844006 https://reactome.org/PathwayBrowser/#/R-SSC-9844006 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) IEA Sus scrofa A0A287AKZ6 R-SSC-9844057 https://reactome.org/PathwayBrowser/#/R-SSC-9844057 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome IEA Sus scrofa A0A287AKZ9 R-SSC-1222516 https://reactome.org/PathwayBrowser/#/R-SSC-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Sus scrofa A0A287AKZ9 R-SSC-5252133 https://reactome.org/PathwayBrowser/#/R-SSC-5252133 ATP6AP1 binds V-ATPase IEA Sus scrofa A0A287AKZ9 R-SSC-74723 https://reactome.org/PathwayBrowser/#/R-SSC-74723 Endosome acidification IEA Sus scrofa A0A287AKZ9 R-SSC-917841 https://reactome.org/PathwayBrowser/#/R-SSC-917841 Acidification of Tf:TfR1 containing endosome IEA Sus scrofa A0A287AKZ9 R-SSC-9639286 https://reactome.org/PathwayBrowser/#/R-SSC-9639286 RRAGC,D exchanges GTP for GDP IEA Sus scrofa A0A287AKZ9 R-SSC-9640167 https://reactome.org/PathwayBrowser/#/R-SSC-9640167 RRAGA,B exchanges GDP for GTP IEA Sus scrofa A0A287AKZ9 R-SSC-9640168 https://reactome.org/PathwayBrowser/#/R-SSC-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Sus scrofa A0A287AKZ9 R-SSC-9640175 https://reactome.org/PathwayBrowser/#/R-SSC-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Sus scrofa A0A287AKZ9 R-SSC-9640195 https://reactome.org/PathwayBrowser/#/R-SSC-9640195 RRAGA,B hydrolyzes GTP IEA Sus scrofa A0A287AKZ9 R-SSC-9645598 https://reactome.org/PathwayBrowser/#/R-SSC-9645598 RRAGC,D hydrolyzes GTP IEA Sus scrofa A0A287AKZ9 R-SSC-9645608 https://reactome.org/PathwayBrowser/#/R-SSC-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Sus scrofa A0A287AKZ9 R-SSC-9646468 https://reactome.org/PathwayBrowser/#/R-SSC-9646468 mTORC1 binds RHEB:GTP IEA Sus scrofa A0A287AL00 R-SSC-2584246 https://reactome.org/PathwayBrowser/#/R-SSC-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Sus scrofa A0A287AL00 R-SSC-8850529 https://reactome.org/PathwayBrowser/#/R-SSC-8850529 RGS proteins bind GNB5 and CCT/TRiC IEA Sus scrofa A0A287AL00 R-SSC-8850539 https://reactome.org/PathwayBrowser/#/R-SSC-8850539 Release of GNB5:RGS dimers from CCT/TRiC IEA Sus scrofa A0A287AL00 R-SSC-8982012 https://reactome.org/PathwayBrowser/#/R-SSC-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Sus scrofa A0A287AL00 R-SSC-8982019 https://reactome.org/PathwayBrowser/#/R-SSC-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Sus scrofa A0A287AL00 R-SSC-8982020 https://reactome.org/PathwayBrowser/#/R-SSC-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Sus scrofa A0A287AL05 R-SSC-156808 https://reactome.org/PathwayBrowser/#/R-SSC-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Sus scrofa A0A287AL05 R-SSC-156823 https://reactome.org/PathwayBrowser/#/R-SSC-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Sus scrofa A0A287AL05 R-SSC-157849 https://reactome.org/PathwayBrowser/#/R-SSC-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Sus scrofa A0A287AL05 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa A0A287AL05 R-SSC-72676 https://reactome.org/PathwayBrowser/#/R-SSC-72676 eIF3 and eIF1A bind to the 40S subunit IEA Sus scrofa A0A287AL05 R-SSC-72691 https://reactome.org/PathwayBrowser/#/R-SSC-72691 Formation of the 43S pre-initiation complex IEA Sus scrofa A0A287AL05 R-SSC-72697 https://reactome.org/PathwayBrowser/#/R-SSC-72697 Start codon recognition IEA Sus scrofa A0A287AL07 R-SSC-9018774 https://reactome.org/PathwayBrowser/#/R-SSC-9018774 RHOBTB1 binds GTP IEA Sus scrofa A0A287AL07 R-SSC-9018778 https://reactome.org/PathwayBrowser/#/R-SSC-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Sus scrofa A0A287AL10 R-SSC-1562626 https://reactome.org/PathwayBrowser/#/R-SSC-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Sus scrofa A0A287AL10 R-SSC-6798745 https://reactome.org/PathwayBrowser/#/R-SSC-6798745 Exocytosis of tertiary granule lumen proteins IEA Sus scrofa A0A287AL10 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287AL21 R-SSC-418365 https://reactome.org/PathwayBrowser/#/R-SSC-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Sus scrofa A0A287AL21 R-SSC-427910 https://reactome.org/PathwayBrowser/#/R-SSC-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Sus scrofa A0A287AL22 R-SSC-109637 https://reactome.org/PathwayBrowser/#/R-SSC-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Sus scrofa A0A287AL22 R-SSC-109638 https://reactome.org/PathwayBrowser/#/R-SSC-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Sus scrofa A0A287AL22 R-SSC-109639 https://reactome.org/PathwayBrowser/#/R-SSC-109639 Formation of the closed pre-initiation complex IEA Sus scrofa A0A287AL22 R-SSC-6810233 https://reactome.org/PathwayBrowser/#/R-SSC-6810233 CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter IEA Sus scrofa A0A287AL22 R-SSC-6810235 https://reactome.org/PathwayBrowser/#/R-SSC-6810235 RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain IEA Sus scrofa A0A287AL22 R-SSC-6810238 https://reactome.org/PathwayBrowser/#/R-SSC-6810238 RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) IEA Sus scrofa A0A287AL22 R-SSC-6814549 https://reactome.org/PathwayBrowser/#/R-SSC-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Sus scrofa A0A287AL22 R-SSC-6814555 https://reactome.org/PathwayBrowser/#/R-SSC-6814555 Integrator complex processes the 3' end of snRNA IEA Sus scrofa A0A287AL22 R-SSC-6814559 https://reactome.org/PathwayBrowser/#/R-SSC-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Sus scrofa A0A287AL22 R-SSC-6814885 https://reactome.org/PathwayBrowser/#/R-SSC-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Sus scrofa A0A287AL22 R-SSC-73946 https://reactome.org/PathwayBrowser/#/R-SSC-73946 Abortive initiation after formation of the first phosphodiester bond IEA Sus scrofa A0A287AL22 R-SSC-75095 https://reactome.org/PathwayBrowser/#/R-SSC-75095 Binding of TFIIE to the growing preinitiation complex IEA Sus scrofa A0A287AL22 R-SSC-75850 https://reactome.org/PathwayBrowser/#/R-SSC-75850 Addition of the third nucleotide on the nascent transcript IEA Sus scrofa A0A287AL22 R-SSC-75856 https://reactome.org/PathwayBrowser/#/R-SSC-75856 Abortive Initiation Before Second Transition IEA Sus scrofa A0A287AL22 R-SSC-75861 https://reactome.org/PathwayBrowser/#/R-SSC-75861 NTP Binds Active Site of RNA Polymerase II IEA Sus scrofa A0A287AL22 R-SSC-75862 https://reactome.org/PathwayBrowser/#/R-SSC-75862 Fall Back to Closed Pre-initiation Complex IEA Sus scrofa A0A287AL22 R-SSC-75864 https://reactome.org/PathwayBrowser/#/R-SSC-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Sus scrofa A0A287AL22 R-SSC-75866 https://reactome.org/PathwayBrowser/#/R-SSC-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Sus scrofa A0A287AL22 R-SSC-75869 https://reactome.org/PathwayBrowser/#/R-SSC-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Sus scrofa A0A287AL22 R-SSC-75949 https://reactome.org/PathwayBrowser/#/R-SSC-75949 RNA Polymerase II Promoter Opening: First Transition IEA Sus scrofa A0A287AL22 R-SSC-9613494 https://reactome.org/PathwayBrowser/#/R-SSC-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Sus scrofa A0A287AL22 R-SSC-9613497 https://reactome.org/PathwayBrowser/#/R-SSC-9613497 Unwinding DNA for the nascent transcript IEA Sus scrofa A0A287AL34 R-SSC-5358494 https://reactome.org/PathwayBrowser/#/R-SSC-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 IEA Sus scrofa A0A287AL38 R-SSC-983162 https://reactome.org/PathwayBrowser/#/R-SSC-983162 Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases IEA Sus scrofa A0A287AL42 R-SSC-166245 https://reactome.org/PathwayBrowser/#/R-SSC-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex IEA Sus scrofa A0A287AL42 R-SSC-166271 https://reactome.org/PathwayBrowser/#/R-SSC-166271 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 IEA Sus scrofa A0A287AL42 R-SSC-2396002 https://reactome.org/PathwayBrowser/#/R-SSC-2396002 TBK1 is phosphorylated within STING:TBK1:IRF3 complex IEA Sus scrofa A0A287AL42 R-SSC-2396007 https://reactome.org/PathwayBrowser/#/R-SSC-2396007 IRF3 is phosphorylated by TBK1 IEA Sus scrofa A0A287AL42 R-SSC-3249371 https://reactome.org/PathwayBrowser/#/R-SSC-3249371 TBK1 phosphorylates STAT6 at Ser407 IEA Sus scrofa A0A287AL42 R-SSC-3249378 https://reactome.org/PathwayBrowser/#/R-SSC-3249378 STING recruits TBK1 and STAT6 IEA Sus scrofa A0A287AL42 R-SSC-3249390 https://reactome.org/PathwayBrowser/#/R-SSC-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex IEA Sus scrofa A0A287AL42 R-SSC-3249392 https://reactome.org/PathwayBrowser/#/R-SSC-3249392 NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3 IEA Sus scrofa A0A287AL42 R-SSC-83582 https://reactome.org/PathwayBrowser/#/R-SSC-83582 TRADD:TRAF2:RIP1 dissociates from TNF-α:TNFR1 IEA Sus scrofa A0A287AL42 R-SSC-8948709 https://reactome.org/PathwayBrowser/#/R-SSC-8948709 DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 IEA Sus scrofa A0A287AL42 R-SSC-9008684 https://reactome.org/PathwayBrowser/#/R-SSC-9008684 TBK1 phosphorylation IEA Sus scrofa A0A287AL42 R-SSC-937337 https://reactome.org/PathwayBrowser/#/R-SSC-937337 TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination IEA Sus scrofa A0A287AL42 R-SSC-9709831 https://reactome.org/PathwayBrowser/#/R-SSC-9709831 HSP90 binds TBK1 and IRF3 IEA Sus scrofa A0A287AL42 R-SSC-9817397 https://reactome.org/PathwayBrowser/#/R-SSC-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Sus scrofa A0A287AL42 R-SSC-9817411 https://reactome.org/PathwayBrowser/#/R-SSC-9817411 TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex IEA Sus scrofa A0A287AL42 R-SSC-9823904 https://reactome.org/PathwayBrowser/#/R-SSC-9823904 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Sus scrofa A0A287AL42 R-SSC-9823906 https://reactome.org/PathwayBrowser/#/R-SSC-9823906 TBK1 is phosphorylated within the activated TLR4 complex IEA Sus scrofa A0A287AL42 R-SSC-9823910 https://reactome.org/PathwayBrowser/#/R-SSC-9823910 Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Sus scrofa A0A287AL42 R-SSC-9823934 https://reactome.org/PathwayBrowser/#/R-SSC-9823934 OPTN binds TBK1 within the activated TLR4 complex IEA Sus scrofa A0A287AL42 R-SSC-9824888 https://reactome.org/PathwayBrowser/#/R-SSC-9824888 OPTN, TBK1 bind ubiquitinated MOM proteins IEA Sus scrofa A0A287AL42 R-SSC-9824892 https://reactome.org/PathwayBrowser/#/R-SSC-9824892 MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria IEA Sus scrofa A0A287AL42 R-SSC-9824894 https://reactome.org/PathwayBrowser/#/R-SSC-9824894 TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins IEA Sus scrofa A0A287AL42 R-SSC-9824897 https://reactome.org/PathwayBrowser/#/R-SSC-9824897 p-S-TBK1 phosphorylates OPTN IEA Sus scrofa A0A287AL42 R-SSC-9840807 https://reactome.org/PathwayBrowser/#/R-SSC-9840807 OPTN binds ATG9A IEA Sus scrofa A0A287AL53 R-SSC-5694563 https://reactome.org/PathwayBrowser/#/R-SSC-5694563 ABHD10 hydrolyses MPAG IEA Sus scrofa A0A287AL54 R-SSC-2684901 https://reactome.org/PathwayBrowser/#/R-SSC-2684901 ANOs transport cytosolic Cl- to extracellular region IEA Sus scrofa A0A287AL56 R-SSC-190682 https://reactome.org/PathwayBrowser/#/R-SSC-190682 Connexin synthesis (generic) IEA Sus scrofa A0A287AL56 R-SSC-375330 https://reactome.org/PathwayBrowser/#/R-SSC-375330 Connexin 45/Connexin 36 mediated neuronal gap junction communication IEA Sus scrofa A0A287AL56 R-SSC-375342 https://reactome.org/PathwayBrowser/#/R-SSC-375342 Connexin 36 mediated neuronal gap junction communication IEA Sus scrofa A0A287AL59 R-SSC-1483190 https://reactome.org/PathwayBrowser/#/R-SSC-1483190 PETA and CTP are condensed to CDP-ETA by PCY2 IEA Sus scrofa A0A287AL69 R-SSC-351876 https://reactome.org/PathwayBrowser/#/R-SSC-351876 Caspase-mediated cleavage of occludin IEA Sus scrofa A0A287AL73 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AL76 R-SSC-6807872 https://reactome.org/PathwayBrowser/#/R-SSC-6807872 Active ARF recruits coatomer IEA Sus scrofa A0A287AL76 R-SSC-6807875 https://reactome.org/PathwayBrowser/#/R-SSC-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Sus scrofa A0A287AL76 R-SSC-6807877 https://reactome.org/PathwayBrowser/#/R-SSC-6807877 ARFGAPs stimulate ARF GTPase activity IEA Sus scrofa A0A287AL76 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa A0A287AL76 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A287AL76 R-SSC-6809011 https://reactome.org/PathwayBrowser/#/R-SSC-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Sus scrofa A0A287AL76 R-SSC-6811417 https://reactome.org/PathwayBrowser/#/R-SSC-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Sus scrofa A0A287AL76 R-SSC-6811418 https://reactome.org/PathwayBrowser/#/R-SSC-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Sus scrofa A0A287AL76 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa A0A287AL76 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa A0A287AL90 R-SSC-5649873 https://reactome.org/PathwayBrowser/#/R-SSC-5649873 PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site IEA Sus scrofa A0A287AL90 R-SSC-5649883 https://reactome.org/PathwayBrowser/#/R-SSC-5649883 POLB-mediated DNA strand displacement synthesis IEA Sus scrofa A0A287AL90 R-SSC-5651723 https://reactome.org/PathwayBrowser/#/R-SSC-5651723 PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate IEA Sus scrofa A0A287AL90 R-SSC-5651739 https://reactome.org/PathwayBrowser/#/R-SSC-5651739 PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB IEA Sus scrofa A0A287AL90 R-SSC-5651828 https://reactome.org/PathwayBrowser/#/R-SSC-5651828 PARG dePARylates PARP1,PARP2 IEA Sus scrofa A0A287AL90 R-SSC-5687484 https://reactome.org/PathwayBrowser/#/R-SSC-5687484 PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site IEA Sus scrofa A0A287AL90 R-SSC-5687640 https://reactome.org/PathwayBrowser/#/R-SSC-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ IEA Sus scrofa A0A287AL90 R-SSC-5687653 https://reactome.org/PathwayBrowser/#/R-SSC-5687653 PARP1,PARP2 dimers bound to MMEJ sites autoPARylate IEA Sus scrofa A0A287AL90 R-SSC-5689317 https://reactome.org/PathwayBrowser/#/R-SSC-5689317 Formation of the pre-incision complex in GG-NER IEA Sus scrofa A0A287AL90 R-SSC-5689861 https://reactome.org/PathwayBrowser/#/R-SSC-5689861 Recruitment of XPA and release of CAK IEA Sus scrofa A0A287AL90 R-SSC-5690213 https://reactome.org/PathwayBrowser/#/R-SSC-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Sus scrofa A0A287AL90 R-SSC-5690988 https://reactome.org/PathwayBrowser/#/R-SSC-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Sus scrofa A0A287AL90 R-SSC-5690990 https://reactome.org/PathwayBrowser/#/R-SSC-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Sus scrofa A0A287AL90 R-SSC-5690991 https://reactome.org/PathwayBrowser/#/R-SSC-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER IEA Sus scrofa A0A287AL90 R-SSC-5690996 https://reactome.org/PathwayBrowser/#/R-SSC-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Sus scrofa A0A287AL90 R-SSC-5691000 https://reactome.org/PathwayBrowser/#/R-SSC-5691000 TFIIH binds GG-NER site to form a verification complex IEA Sus scrofa A0A287AL90 R-SSC-5696655 https://reactome.org/PathwayBrowser/#/R-SSC-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Sus scrofa A0A287AL90 R-SSC-5696664 https://reactome.org/PathwayBrowser/#/R-SSC-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Sus scrofa A0A287AL90 R-SSC-5696670 https://reactome.org/PathwayBrowser/#/R-SSC-5696670 CHD1L is recruited to GG-NER site IEA Sus scrofa A0A287AL90 R-SSC-6790454 https://reactome.org/PathwayBrowser/#/R-SSC-6790454 SUMOylation of XPC IEA Sus scrofa A0A287AL94 R-SSC-453339 https://reactome.org/PathwayBrowser/#/R-SSC-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Sus scrofa A0A287AL94 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A287AL94 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287AL94 R-SSC-71588 https://reactome.org/PathwayBrowser/#/R-SSC-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Sus scrofa A0A287AL94 R-SSC-71590 https://reactome.org/PathwayBrowser/#/R-SSC-71590 glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] IEA Sus scrofa A0A287ALA0 R-SSC-9693125 https://reactome.org/PathwayBrowser/#/R-SSC-9693125 RHOF binds effectors at the plasma membrane IEA Sus scrofa A0A287ALA1 R-SSC-203973 https://reactome.org/PathwayBrowser/#/R-SSC-203973 Vesicle budding IEA Sus scrofa A0A287ALA1 R-SSC-204008 https://reactome.org/PathwayBrowser/#/R-SSC-204008 SEC31:SEC13 and v-SNARE recruitment IEA Sus scrofa A0A287ALA1 R-SSC-481007 https://reactome.org/PathwayBrowser/#/R-SSC-481007 Exocytosis of platelet alpha granule contents IEA Sus scrofa A0A287ALA1 R-SSC-5694409 https://reactome.org/PathwayBrowser/#/R-SSC-5694409 Nucleotide exchange on RAB1 IEA Sus scrofa A0A287ALA1 R-SSC-5694417 https://reactome.org/PathwayBrowser/#/R-SSC-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Sus scrofa A0A287ALA1 R-SSC-5694418 https://reactome.org/PathwayBrowser/#/R-SSC-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Sus scrofa A0A287ALA1 R-SSC-5694428 https://reactome.org/PathwayBrowser/#/R-SSC-5694428 LMAN family proteins bind glycosylated cargo IEA Sus scrofa A0A287ALA1 R-SSC-5694446 https://reactome.org/PathwayBrowser/#/R-SSC-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Sus scrofa A0A287ALA1 R-SSC-5694522 https://reactome.org/PathwayBrowser/#/R-SSC-5694522 Inner coat assembly and cargo binding IEA Sus scrofa A0A287ALA1 R-SSC-5694527 https://reactome.org/PathwayBrowser/#/R-SSC-5694527 Loss of SAR1B GTPase IEA Sus scrofa A0A287ALA1 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287ALA1 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A287ALB1 R-SSC-5334794 https://reactome.org/PathwayBrowser/#/R-SSC-5334794 FABPs bind LCFAs IEA Sus scrofa A0A287ALB3 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa A0A287ALB3 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa A0A287ALB3 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa A0A287ALC1 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287ALC1 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287ALC1 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287ALC1 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287ALC1 R-SSC-8858498 https://reactome.org/PathwayBrowser/#/R-SSC-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Sus scrofa A0A287ALC1 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287ALC1 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287ALC1 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287ALC1 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287ALC1 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287ALC1 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287ALE6 R-SSC-6788912 https://reactome.org/PathwayBrowser/#/R-SSC-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Sus scrofa A0A287ALG6 R-SSC-1251997 https://reactome.org/PathwayBrowser/#/R-SSC-1251997 Cleavage of ERBB4m80 by gamma-scretase complex IEA Sus scrofa A0A287ALG6 R-SSC-193682 https://reactome.org/PathwayBrowser/#/R-SSC-193682 gamma-secretase cleaves the p75NTR transmembrane domain IEA Sus scrofa A0A287ALG6 R-SSC-3928656 https://reactome.org/PathwayBrowser/#/R-SSC-3928656 gamma-secretase cleaves EPHB2 IEA Sus scrofa A0A287ALG6 R-SSC-9839376 https://reactome.org/PathwayBrowser/#/R-SSC-9839376 TGFBR3(784-851) degradation IEA Sus scrofa A0A287ALH5 R-SSC-350058 https://reactome.org/PathwayBrowser/#/R-SSC-350058 Formation of CSL NCOR corepressor complex IEA Sus scrofa A0A287ALH5 R-SSC-3777129 https://reactome.org/PathwayBrowser/#/R-SSC-3777129 HDAC3 containing complexes deacetylate histone IEA Sus scrofa A0A287ALH5 R-SSC-400183 https://reactome.org/PathwayBrowser/#/R-SSC-400183 PPARA:RXRA binds Corepressors of PPARA IEA Sus scrofa A0A287ALH5 R-SSC-9024326 https://reactome.org/PathwayBrowser/#/R-SSC-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Sus scrofa A0A287ALH5 R-SSC-9024334 https://reactome.org/PathwayBrowser/#/R-SSC-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Sus scrofa A0A287ALH5 R-SSC-9734475 https://reactome.org/PathwayBrowser/#/R-SSC-9734475 PPARA binds fibrates IEA Sus scrofa A0A287ALH5 R-SSC-9843115 https://reactome.org/PathwayBrowser/#/R-SSC-9843115 Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci IEA Sus scrofa A0A287ALH5 R-SSC-9843117 https://reactome.org/PathwayBrowser/#/R-SSC-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Sus scrofa A0A287ALH5 R-SSC-9843118 https://reactome.org/PathwayBrowser/#/R-SSC-9843118 RXRA binds ligands IEA Sus scrofa A0A287ALH7 R-SSC-8940388 https://reactome.org/PathwayBrowser/#/R-SSC-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Sus scrofa A0A287ALJ5 R-SSC-389611 https://reactome.org/PathwayBrowser/#/R-SSC-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA IEA Sus scrofa A0A287ALJ5 R-SSC-9033235 https://reactome.org/PathwayBrowser/#/R-SSC-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A287ALJ5 R-SSC-9033236 https://reactome.org/PathwayBrowser/#/R-SSC-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Sus scrofa A0A287ALJ6 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287ALJ6 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287ALJ6 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287ALJ6 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287ALJ6 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287ALJ6 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287ALJ6 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287ALJ6 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287ALJ6 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287ALJ6 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287ALJ6 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287ALJ6 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287ALJ6 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287ALJ6 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287ALJ6 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287ALJ6 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287ALJ6 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287ALJ6 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287ALJ6 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287ALJ6 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287ALJ6 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287ALJ6 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287ALJ6 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287ALJ6 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287ALJ6 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287ALJ6 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287ALJ6 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287ALJ6 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287ALJ6 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287ALJ6 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287ALJ6 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287ALJ6 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287ALJ6 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287ALJ6 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287ALJ6 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287ALJ6 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287ALJ6 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287ALJ6 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287ALJ6 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287ALJ6 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287ALJ6 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287ALJ6 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287ALJ6 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287ALJ6 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287ALJ6 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287ALJ6 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287ALJ6 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287ALJ7 R-SSC-8864307 https://reactome.org/PathwayBrowser/#/R-SSC-8864307 TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP IEA Sus scrofa A0A287ALJ7 R-SSC-9008271 https://reactome.org/PathwayBrowser/#/R-SSC-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Sus scrofa A0A287ALJ7 R-SSC-9023860 https://reactome.org/PathwayBrowser/#/R-SSC-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Sus scrofa A0A287ALJ8 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287ALK4 R-SSC-212352 https://reactome.org/PathwayBrowser/#/R-SSC-212352 Formation of ARC coactivator complex IEA Sus scrofa A0A287ALK4 R-SSC-212380 https://reactome.org/PathwayBrowser/#/R-SSC-212380 Formation of TRAP coactivator complex IEA Sus scrofa A0A287ALK4 R-SSC-212432 https://reactome.org/PathwayBrowser/#/R-SSC-212432 Formation of DRIP coactivator complex IEA Sus scrofa A0A287ALK4 R-SSC-2176475 https://reactome.org/PathwayBrowser/#/R-SSC-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 IEA Sus scrofa A0A287ALK4 R-SSC-9843120 https://reactome.org/PathwayBrowser/#/R-SSC-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Sus scrofa A0A287ALL0 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A287ALL0 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287ALL0 R-SSC-8848484 https://reactome.org/PathwayBrowser/#/R-SSC-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Sus scrofa A0A287ALL2 R-SSC-163090 https://reactome.org/PathwayBrowser/#/R-SSC-163090 Elongation Of The Telomeric Chromosome End IEA Sus scrofa A0A287ALL2 R-SSC-163096 https://reactome.org/PathwayBrowser/#/R-SSC-163096 Recruitment of Telomerase RNP to the Telomeric Chromosome End IEA Sus scrofa A0A287ALL2 R-SSC-163099 https://reactome.org/PathwayBrowser/#/R-SSC-163099 Alignment Of The RNA Template On The Telomeric Chromosome End IEA Sus scrofa A0A287ALL2 R-SSC-163120 https://reactome.org/PathwayBrowser/#/R-SSC-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Sus scrofa A0A287ALL2 R-SSC-164617 https://reactome.org/PathwayBrowser/#/R-SSC-164617 Elongation of Extended Telomeric Chromosome End IEA Sus scrofa A0A287ALL2 R-SSC-164620 https://reactome.org/PathwayBrowser/#/R-SSC-164620 Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End IEA Sus scrofa A0A287ALL2 R-SSC-174425 https://reactome.org/PathwayBrowser/#/R-SSC-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Sus scrofa A0A287ALL2 R-SSC-174427 https://reactome.org/PathwayBrowser/#/R-SSC-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Sus scrofa A0A287ALL2 R-SSC-174438 https://reactome.org/PathwayBrowser/#/R-SSC-174438 Formation of the Flap Intermediate on the C-strand IEA Sus scrofa A0A287ALL2 R-SSC-174439 https://reactome.org/PathwayBrowser/#/R-SSC-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Sus scrofa A0A287ALL2 R-SSC-174441 https://reactome.org/PathwayBrowser/#/R-SSC-174441 Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand IEA Sus scrofa A0A287ALL2 R-SSC-174444 https://reactome.org/PathwayBrowser/#/R-SSC-174444 Formation of C-strand Okazaki fragments IEA Sus scrofa A0A287ALL2 R-SSC-174445 https://reactome.org/PathwayBrowser/#/R-SSC-174445 RPA binds to the Flap on the C-strand IEA Sus scrofa A0A287ALL2 R-SSC-174446 https://reactome.org/PathwayBrowser/#/R-SSC-174446 Removal of remaining Flap from the C-strand IEA Sus scrofa A0A287ALL2 R-SSC-174447 https://reactome.org/PathwayBrowser/#/R-SSC-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Sus scrofa A0A287ALL2 R-SSC-174448 https://reactome.org/PathwayBrowser/#/R-SSC-174448 Formation of Processive Complex on the C-strand of the telomere IEA Sus scrofa A0A287ALL2 R-SSC-174451 https://reactome.org/PathwayBrowser/#/R-SSC-174451 Recruitment of DNA2 endonuclease to the C strand IEA Sus scrofa A0A287ALL2 R-SSC-174452 https://reactome.org/PathwayBrowser/#/R-SSC-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Sus scrofa A0A287ALL2 R-SSC-174456 https://reactome.org/PathwayBrowser/#/R-SSC-174456 Joining of adjacent Okazaki fragments of the C-strand IEA Sus scrofa A0A287ALL2 R-SSC-176702 https://reactome.org/PathwayBrowser/#/R-SSC-176702 Disassociation of Processive Complex and Completed Telomere End IEA Sus scrofa A0A287ALL2 R-SSC-3785711 https://reactome.org/PathwayBrowser/#/R-SSC-3785711 Telomere shortening during replicative exhaustion IEA Sus scrofa A0A287ALL2 R-SSC-9629195 https://reactome.org/PathwayBrowser/#/R-SSC-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA IEA Sus scrofa A0A287ALL2 R-SSC-9629216 https://reactome.org/PathwayBrowser/#/R-SSC-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Sus scrofa A0A287ALL2 R-SSC-9668597 https://reactome.org/PathwayBrowser/#/R-SSC-9668597 DNA polymerase:primase binds G-strand of the telomere IEA Sus scrofa A0A287ALL2 R-SSC-9670101 https://reactome.org/PathwayBrowser/#/R-SSC-9670101 ATRX:DAXX binds to subtelomeric chromosomal regions IEA Sus scrofa A0A287ALL2 R-SSC-9686521 https://reactome.org/PathwayBrowser/#/R-SSC-9686521 CDK2:CCNA phosphorylates TERF2 IEA Sus scrofa A0A287ALL2 R-SSC-9686524 https://reactome.org/PathwayBrowser/#/R-SSC-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Sus scrofa A0A287ALL6 R-SSC-176298 https://reactome.org/PathwayBrowser/#/R-SSC-176298 Activation of claspin IEA Sus scrofa A0A287ALL6 R-SSC-176318 https://reactome.org/PathwayBrowser/#/R-SSC-176318 Loading of claspin onto DNA during replication origin firing IEA Sus scrofa A0A287ALL6 R-SSC-68603 https://reactome.org/PathwayBrowser/#/R-SSC-68603 ORC5 binds ORC2:ORC3 IEA Sus scrofa A0A287ALL6 R-SSC-68610 https://reactome.org/PathwayBrowser/#/R-SSC-68610 Formation of ORC(2-5) complex IEA Sus scrofa A0A287ALL6 R-SSC-68611 https://reactome.org/PathwayBrowser/#/R-SSC-68611 Formation of ORC(1-5) complex IEA Sus scrofa A0A287ALL6 R-SSC-68615 https://reactome.org/PathwayBrowser/#/R-SSC-68615 Formation of ORC(1-6) complex IEA Sus scrofa A0A287ALL6 R-SSC-68688 https://reactome.org/PathwayBrowser/#/R-SSC-68688 CDC6 association with ORC(1-6) at replication origins IEA Sus scrofa A0A287ALL6 R-SSC-68914 https://reactome.org/PathwayBrowser/#/R-SSC-68914 DNA polymerase alpha:primase binds at the origin IEA Sus scrofa A0A287ALL6 R-SSC-68916 https://reactome.org/PathwayBrowser/#/R-SSC-68916 DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin IEA Sus scrofa A0A287ALL6 R-SSC-68917 https://reactome.org/PathwayBrowser/#/R-SSC-68917 Cdc45 associates with the pre-replicative complex at the origin IEA Sus scrofa A0A287ALL6 R-SSC-68918 https://reactome.org/PathwayBrowser/#/R-SSC-68918 CDK and DDK associate with the Mcm10:pre-replicative complex IEA Sus scrofa A0A287ALL6 R-SSC-68919 https://reactome.org/PathwayBrowser/#/R-SSC-68919 Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 IEA Sus scrofa A0A287ALL6 R-SSC-68940 https://reactome.org/PathwayBrowser/#/R-SSC-68940 Cdt1 is displaced from the pre-replicative complex IEA Sus scrofa A0A287ALL6 R-SSC-68944 https://reactome.org/PathwayBrowser/#/R-SSC-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Sus scrofa A0A287ALL6 R-SSC-68960 https://reactome.org/PathwayBrowser/#/R-SSC-68960 DNA polymerase epsilon binds at the origin IEA Sus scrofa A0A287ALM1 R-SSC-76590 https://reactome.org/PathwayBrowser/#/R-SSC-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Sus scrofa A0A287ALM4 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287ALN0 R-SSC-5620975 https://reactome.org/PathwayBrowser/#/R-SSC-5620975 MLKL binds PIPs IEA Sus scrofa A0A287ALN0 R-SSC-8849908 https://reactome.org/PathwayBrowser/#/R-SSC-8849908 SALM4 binds flotillin-1 IEA Sus scrofa A0A287ALN0 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa A0A287ALN0 R-SSC-9013024 https://reactome.org/PathwayBrowser/#/R-SSC-9013024 RHOB binds effectors at the plasma membrane IEA Sus scrofa A0A287ALN0 R-SSC-9013110 https://reactome.org/PathwayBrowser/#/R-SSC-9013110 RHOC binds effectors at the plasma membrane IEA Sus scrofa A0A287ALN0 R-SSC-9688456 https://reactome.org/PathwayBrowser/#/R-SSC-9688456 MLKL binds FLOT1, FLOT2 IEA Sus scrofa A0A287ALN0 R-SSC-9696268 https://reactome.org/PathwayBrowser/#/R-SSC-9696268 RND3 binds effectors IEA Sus scrofa A0A287ALN0 R-SSC-9696271 https://reactome.org/PathwayBrowser/#/R-SSC-9696271 RND1 binds effectors IEA Sus scrofa A0A287ALN2 R-SSC-9861563 https://reactome.org/PathwayBrowser/#/R-SSC-9861563 CTLH E3 ligase ubiquitinates LDHA IEA Sus scrofa A0A287ALN2 R-SSC-9861640 https://reactome.org/PathwayBrowser/#/R-SSC-9861640 CTLH E3 ligase ubiquitinates PKM-1 IEA Sus scrofa A0A287ALP1 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A287ALR5 R-SSC-159431 https://reactome.org/PathwayBrowser/#/R-SSC-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Sus scrofa A0A287ALR5 R-SSC-192312 https://reactome.org/PathwayBrowser/#/R-SSC-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate IEA Sus scrofa A0A287ALR5 R-SSC-193491 https://reactome.org/PathwayBrowser/#/R-SSC-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Sus scrofa A0A287ALR5 R-SSC-9033235 https://reactome.org/PathwayBrowser/#/R-SSC-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A287ALR5 R-SSC-9033236 https://reactome.org/PathwayBrowser/#/R-SSC-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Sus scrofa A0A287ALS6 R-SSC-9838035 https://reactome.org/PathwayBrowser/#/R-SSC-9838035 CLPXP binds mitochondrial matrix proteins IEA Sus scrofa A0A287ALS6 R-SSC-9838081 https://reactome.org/PathwayBrowser/#/R-SSC-9838081 LONP1 degrades mitochondrial matrix proteins IEA Sus scrofa A0A287ALS6 R-SSC-9838093 https://reactome.org/PathwayBrowser/#/R-SSC-9838093 LONP1 binds mitochondrial matrix proteins IEA Sus scrofa A0A287ALS6 R-SSC-9838289 https://reactome.org/PathwayBrowser/#/R-SSC-9838289 CLPXP degrades mitochondrial matrix proteins IEA Sus scrofa A0A287ALS6 R-SSC-9914404 https://reactome.org/PathwayBrowser/#/R-SSC-9914404 POLRMT and POLG bind the mitochondrial L strand replication origin (OriL) IEA Sus scrofa A0A287ALS6 R-SSC-9914409 https://reactome.org/PathwayBrowser/#/R-SSC-9914409 POLRMT polymerizes RNA primer for mitochondrial L strand replication IEA Sus scrofa A0A287ALS6 R-SSC-9914478 https://reactome.org/PathwayBrowser/#/R-SSC-9914478 SSBP1 binds the displaced parental H strand IEA Sus scrofa A0A287ALS6 R-SSC-9914498 https://reactome.org/PathwayBrowser/#/R-SSC-9914498 POLG in the replisome polymerizes the L strand IEA Sus scrofa A0A287ALU0 R-SSC-2993447 https://reactome.org/PathwayBrowser/#/R-SSC-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Sus scrofa A0A287ALU0 R-SSC-3323111 https://reactome.org/PathwayBrowser/#/R-SSC-3323111 Cytoslic carboxylases translocate to mitochondrial matrix IEA Sus scrofa A0A287ALU0 R-SSC-71031 https://reactome.org/PathwayBrowser/#/R-SSC-71031 propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate IEA Sus scrofa A0A287ALW8 R-SSC-380574 https://reactome.org/PathwayBrowser/#/R-SSC-380574 Dopamine synaptic vesicle docking and priming IEA Sus scrofa A0A287ALW8 R-SSC-380869 https://reactome.org/PathwayBrowser/#/R-SSC-380869 Release of docked dopamine loaded synaptic vesicle IEA Sus scrofa A0A287ALW8 R-SSC-380901 https://reactome.org/PathwayBrowser/#/R-SSC-380901 Release of docked serotonin loaded synaptic vesicle IEA Sus scrofa A0A287ALW8 R-SSC-380905 https://reactome.org/PathwayBrowser/#/R-SSC-380905 Serotonin loaded synaptic vesicle docking and priming IEA Sus scrofa A0A287ALW9 R-SSC-3108212 https://reactome.org/PathwayBrowser/#/R-SSC-3108212 SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 IEA Sus scrofa A0A287ALX5 R-SSC-5689630 https://reactome.org/PathwayBrowser/#/R-SSC-5689630 BAP1 binds BAP1-interacting complex IEA Sus scrofa A0A287ALX5 R-SSC-5690790 https://reactome.org/PathwayBrowser/#/R-SSC-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Sus scrofa A0A287ALY1 R-SSC-211951 https://reactome.org/PathwayBrowser/#/R-SSC-211951 CYP1B1 4-hydroxylates EST17b IEA Sus scrofa A0A287ALY1 R-SSC-5692283 https://reactome.org/PathwayBrowser/#/R-SSC-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Sus scrofa A0A287ALY1 R-SSC-76472 https://reactome.org/PathwayBrowser/#/R-SSC-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Sus scrofa A0A287ALY1 R-SSC-8936851 https://reactome.org/PathwayBrowser/#/R-SSC-8936851 AHRR binds ARNT IEA Sus scrofa A0A287ALY7 R-SSC-8952626 https://reactome.org/PathwayBrowser/#/R-SSC-8952626 AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex IEA Sus scrofa A0A287ALY7 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287ALY7 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287ALY7 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AM09 R-SSC-3108203 https://reactome.org/PathwayBrowser/#/R-SSC-3108203 PRC1 SUMOylates CTBP1 with SUMO2,3 IEA Sus scrofa A0A287AM09 R-SSC-3108209 https://reactome.org/PathwayBrowser/#/R-SSC-3108209 PRC1 SUMOylates CTBP1 with SUMO1 IEA Sus scrofa A0A287AM09 R-SSC-3361751 https://reactome.org/PathwayBrowser/#/R-SSC-3361751 beta-catenin is replaced by repression complexes at the promoter IEA Sus scrofa A0A287AM09 R-SSC-5334050 https://reactome.org/PathwayBrowser/#/R-SSC-5334050 TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes IEA Sus scrofa A0A287AM10 R-SSC-437085 https://reactome.org/PathwayBrowser/#/R-SSC-437085 ZnT5 transports zinc into secretory granules in pancreatic beta cells IEA Sus scrofa A0A287AM10 R-SSC-9820566 https://reactome.org/PathwayBrowser/#/R-SSC-9820566 ZnT5 transports zinc into the golgi apparatus IEA Sus scrofa A0A287AM17 R-SSC-8849102 https://reactome.org/PathwayBrowser/#/R-SSC-8849102 SRMS phosphorylates PTK6 IEA Sus scrofa A0A287AM21 R-SSC-8851797 https://reactome.org/PathwayBrowser/#/R-SSC-8851797 ADRB2 in ADRB2:GRK complex is phosphorylated IEA Sus scrofa A0A287AM21 R-SSC-8982641 https://reactome.org/PathwayBrowser/#/R-SSC-8982641 ADRB2:GRK complex dissociates to Phosphorylated ADRB2 IEA Sus scrofa A0A287AM21 R-SSC-8982645 https://reactome.org/PathwayBrowser/#/R-SSC-8982645 GRKs bind ADRB2:Catecholamine IEA Sus scrofa A0A287AM30 R-SSC-1362261 https://reactome.org/PathwayBrowser/#/R-SSC-1362261 p130 (RBL2) associates with MuvB to form DREAM complex IEA Sus scrofa A0A287AM30 R-SSC-1362270 https://reactome.org/PathwayBrowser/#/R-SSC-1362270 Phosphorylation of LIN52 component of MuvB by DYRK1A IEA Sus scrofa A0A287AM30 R-SSC-212222 https://reactome.org/PathwayBrowser/#/R-SSC-212222 PRC2 recruits DNA methyltransferases IEA Sus scrofa A0A287AM30 R-SSC-212252 https://reactome.org/PathwayBrowser/#/R-SSC-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Sus scrofa A0A287AM30 R-SSC-212263 https://reactome.org/PathwayBrowser/#/R-SSC-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Sus scrofa A0A287AM30 R-SSC-212269 https://reactome.org/PathwayBrowser/#/R-SSC-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Sus scrofa A0A287AM30 R-SSC-3240295 https://reactome.org/PathwayBrowser/#/R-SSC-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Sus scrofa A0A287AM30 R-SSC-3240957 https://reactome.org/PathwayBrowser/#/R-SSC-3240957 Formation of PRC2-EZH2 complex IEA Sus scrofa A0A287AM30 R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa A0A287AM30 R-SSC-5638332 https://reactome.org/PathwayBrowser/#/R-SSC-5638332 PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) IEA Sus scrofa A0A287AM30 R-SSC-606287 https://reactome.org/PathwayBrowser/#/R-SSC-606287 RSF complex binds the centromere IEA Sus scrofa A0A287AM30 R-SSC-606326 https://reactome.org/PathwayBrowser/#/R-SSC-606326 HJURP:CENPA complex localizes to the centromere IEA Sus scrofa A0A287AM30 R-SSC-6805650 https://reactome.org/PathwayBrowser/#/R-SSC-6805650 MTA2-NuRD complex deacetylates TP53 IEA Sus scrofa A0A287AM30 R-SSC-73739 https://reactome.org/PathwayBrowser/#/R-SSC-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter IEA Sus scrofa A0A287AM30 R-SSC-8943780 https://reactome.org/PathwayBrowser/#/R-SSC-8943780 SALL4 recruits NuRD to PTEN gene IEA Sus scrofa A0A287AM30 R-SSC-8943817 https://reactome.org/PathwayBrowser/#/R-SSC-8943817 MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter IEA Sus scrofa A0A287AM30 R-SSC-8954110 https://reactome.org/PathwayBrowser/#/R-SSC-8954110 E2F6:TFDP1:EPC1 binds the PRC2 complex IEA Sus scrofa A0A287AM30 R-SSC-9679787 https://reactome.org/PathwayBrowser/#/R-SSC-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Sus scrofa A0A287AM45 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287AM45 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287AM45 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287AM45 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287AM45 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287AM45 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287AM45 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287AM45 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287AM45 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287AM45 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AM45 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287AM45 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287AM45 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287AM45 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287AM45 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287AM45 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287AM45 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287AM45 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287AM45 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287AM45 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287AM45 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287AM45 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287AM45 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287AM45 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287AM45 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287AM45 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287AM45 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287AM45 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287AM45 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287AM45 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287AM45 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287AM45 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287AM45 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287AM45 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287AM45 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287AM45 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287AM45 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287AM45 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287AM45 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287AM45 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287AM45 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287AM45 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287AM45 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287AM45 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287AM45 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287AM45 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287AM45 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287AM58 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287AM58 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287AM58 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287AM58 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287AM58 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287AM58 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287AM58 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287AM58 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287AM58 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287AM58 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AM58 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287AM58 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287AM58 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287AM58 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287AM58 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287AM58 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287AM58 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287AM58 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287AM58 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287AM58 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287AM58 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287AM58 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287AM58 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287AM58 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287AM58 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287AM58 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287AM58 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287AM58 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287AM58 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287AM58 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287AM58 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287AM58 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287AM58 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287AM58 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287AM58 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287AM58 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287AM58 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287AM58 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287AM58 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287AM58 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287AM58 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287AM58 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287AM58 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287AM58 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287AM58 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287AM58 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287AM58 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287AM88 R-SSC-2002466 https://reactome.org/PathwayBrowser/#/R-SSC-2002466 Formation of allysine by LOX IEA Sus scrofa A0A287AM88 R-SSC-2022141 https://reactome.org/PathwayBrowser/#/R-SSC-2022141 Prolysyl oxidase activation IEA Sus scrofa A0A287AM88 R-SSC-2129375 https://reactome.org/PathwayBrowser/#/R-SSC-2129375 Elastin cross-linking by lysyl oxidase IEA Sus scrofa A0A287AM88 R-SSC-2395340 https://reactome.org/PathwayBrowser/#/R-SSC-2395340 Formation of hydroxyallysine by LOX IEA Sus scrofa A0A287AM95 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A287AM98 R-SSC-1482889 https://reactome.org/PathwayBrowser/#/R-SSC-1482889 DAG is acylated to TAG by DGAT1/2 IEA Sus scrofa A0A287AM98 R-SSC-549192 https://reactome.org/PathwayBrowser/#/R-SSC-549192 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] IEA Sus scrofa A0A287AM99 R-SSC-174439 https://reactome.org/PathwayBrowser/#/R-SSC-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Sus scrofa A0A287AM99 R-SSC-174447 https://reactome.org/PathwayBrowser/#/R-SSC-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere IEA Sus scrofa A0A287AM99 R-SSC-174452 https://reactome.org/PathwayBrowser/#/R-SSC-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Sus scrofa A0A287AMB4 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287AMB4 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287AMB4 R-SSC-2466068 https://reactome.org/PathwayBrowser/#/R-SSC-2466068 Phosphorylation of cohesin by PLK1 at chromosomal arms IEA Sus scrofa A0A287AMB4 R-SSC-2467794 https://reactome.org/PathwayBrowser/#/R-SSC-2467794 Resolution of sister chromatids IEA Sus scrofa A0A287AMB4 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287AMB4 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287AMB4 R-SSC-2468041 https://reactome.org/PathwayBrowser/#/R-SSC-2468041 CDCA5 (Sororin) enables cohesion of sister chromosomal arms IEA Sus scrofa A0A287AMB4 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287AMB4 R-SSC-2468293 https://reactome.org/PathwayBrowser/#/R-SSC-2468293 CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms IEA Sus scrofa A0A287AMB4 R-SSC-2473151 https://reactome.org/PathwayBrowser/#/R-SSC-2473151 CDCA5 (Sororin) enables cohesion of sister centromeres IEA Sus scrofa A0A287AMB4 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287AMB8 R-SSC-1011598 https://reactome.org/PathwayBrowser/#/R-SSC-1011598 DOCKs bind to RhoGEFs IEA Sus scrofa A0A287AMB8 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A287AMB8 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa A0A287AMB8 R-SSC-9017491 https://reactome.org/PathwayBrowser/#/R-SSC-9017491 RHOJ GEFs activate RHOJ IEA Sus scrofa A0A287AMB9 R-SSC-5617037 https://reactome.org/PathwayBrowser/#/R-SSC-5617037 POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 IEA Sus scrofa A0A287AMD1 R-SSC-4085994 https://reactome.org/PathwayBrowser/#/R-SSC-4085994 TOPORS SUMOylates SIN3A with SUMO1 IEA Sus scrofa A0A287AMD1 R-SSC-4551683 https://reactome.org/PathwayBrowser/#/R-SSC-4551683 SUMOylation of TOPORS with SUMO1 IEA Sus scrofa A0A287AMD1 R-SSC-4755478 https://reactome.org/PathwayBrowser/#/R-SSC-4755478 TOPORS SUMOylates IKBKE with SUMO1 IEA Sus scrofa A0A287AMD4 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287AMD7 R-SSC-8937631 https://reactome.org/PathwayBrowser/#/R-SSC-8937631 CRHR2-2 binds CRH,UCN,UCN2,UCN3 IEA Sus scrofa A0A287AME3 R-SSC-416690 https://reactome.org/PathwayBrowser/#/R-SSC-416690 SEMA4A binds to PLXND1 IEA Sus scrofa A0A287AMH6 R-SSC-6806831 https://reactome.org/PathwayBrowser/#/R-SSC-6806831 CYB5Rs reduce MetHb to HbA IEA Sus scrofa A0A287AMI4 R-SSC-5696958 https://reactome.org/PathwayBrowser/#/R-SSC-5696958 USP44 deubiquitinates CDC20 IEA Sus scrofa A0A287AMJ0 R-SSC-1169406 https://reactome.org/PathwayBrowser/#/R-SSC-1169406 ISGylation of host proteins IEA Sus scrofa A0A287AMJ0 R-SSC-1678841 https://reactome.org/PathwayBrowser/#/R-SSC-1678841 Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 IEA Sus scrofa A0A287AMJ0 R-SSC-5690159 https://reactome.org/PathwayBrowser/#/R-SSC-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Sus scrofa A0A287AMJ0 R-SSC-5696564 https://reactome.org/PathwayBrowser/#/R-SSC-5696564 USP25 deubiquitinates DDX58 IEA Sus scrofa A0A287AMJ0 R-SSC-5696600 https://reactome.org/PathwayBrowser/#/R-SSC-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Sus scrofa A0A287AMJ0 R-SSC-8985153 https://reactome.org/PathwayBrowser/#/R-SSC-8985153 OASL binds DDX58 IEA Sus scrofa A0A287AMJ0 R-SSC-936390 https://reactome.org/PathwayBrowser/#/R-SSC-936390 CYLD mediated deubiquitination of DDX58 (RIG-I) IEA Sus scrofa A0A287AMJ0 R-SSC-936563 https://reactome.org/PathwayBrowser/#/R-SSC-936563 ISGylation of DDX58 IEA Sus scrofa A0A287AMJ0 R-SSC-9927247 https://reactome.org/PathwayBrowser/#/R-SSC-9927247 ISGylation of DDX58 (RIG-I) IEA Sus scrofa A0A287AMN2 R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Sus scrofa A0A287AMN2 R-SSC-6799179 https://reactome.org/PathwayBrowser/#/R-SSC-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Sus scrofa A0A287AMN2 R-SSC-6799196 https://reactome.org/PathwayBrowser/#/R-SSC-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Sus scrofa A0A287AMP9 R-SSC-1955380 https://reactome.org/PathwayBrowser/#/R-SSC-1955380 TIMM9:TIMM10 transfers proteins to TIMM22 IEA Sus scrofa A0A287AMQ0 R-SSC-3299569 https://reactome.org/PathwayBrowser/#/R-SSC-3299569 Beta-catenin displaces TLE:HDAC1 from TCF/LEF IEA Sus scrofa A0A287AMQ0 R-SSC-3322429 https://reactome.org/PathwayBrowser/#/R-SSC-3322429 XIAP monoubiquinates TLE IEA Sus scrofa A0A287AMQ0 R-SSC-3322431 https://reactome.org/PathwayBrowser/#/R-SSC-3322431 XIAP binds TLE IEA Sus scrofa A0A287AMQ0 R-SSC-3322434 https://reactome.org/PathwayBrowser/#/R-SSC-3322434 XIAP dissociates from ub-TLE IEA Sus scrofa A0A287AMQ0 R-SSC-3361751 https://reactome.org/PathwayBrowser/#/R-SSC-3361751 beta-catenin is replaced by repression complexes at the promoter IEA Sus scrofa A0A287AMQ0 R-SSC-4641229 https://reactome.org/PathwayBrowser/#/R-SSC-4641229 TLE oligomerizes IEA Sus scrofa A0A287AMQ0 R-SSC-8944349 https://reactome.org/PathwayBrowser/#/R-SSC-8944349 TLE tetramers bind TCF/LEF at WNT promoters IEA Sus scrofa A0A287AMQ7 R-SSC-5633051 https://reactome.org/PathwayBrowser/#/R-SSC-5633051 EFCAB7:IQCE binds EVC2:EVC IEA Sus scrofa A0A287AMR3 R-SSC-8940388 https://reactome.org/PathwayBrowser/#/R-SSC-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Sus scrofa A0A287AMR9 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287AMR9 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AMR9 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AMR9 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AMR9 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287AMR9 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AMR9 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AMS8 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287AMT4 R-SSC-444120 https://reactome.org/PathwayBrowser/#/R-SSC-444120 SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol IEA Sus scrofa A0A287AMT7 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AMT7 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287AMT7 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AMT7 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AMU7 R-SSC-2046285 https://reactome.org/PathwayBrowser/#/R-SSC-2046285 The keratan chain can be capped by N-acetylneuraminic acid IEA Sus scrofa A0A287AMU7 R-SSC-4084984 https://reactome.org/PathwayBrowser/#/R-SSC-4084984 ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) IEA Sus scrofa A0A287AMU7 R-SSC-9605600 https://reactome.org/PathwayBrowser/#/R-SSC-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Sus scrofa A0A287AMV0 R-SSC-6797630 https://reactome.org/PathwayBrowser/#/R-SSC-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Sus scrofa A0A287AMV7 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AMW5 R-SSC-212252 https://reactome.org/PathwayBrowser/#/R-SSC-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Sus scrofa A0A287AMW5 R-SSC-212263 https://reactome.org/PathwayBrowser/#/R-SSC-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Sus scrofa A0A287AMX7 R-SSC-8932275 https://reactome.org/PathwayBrowser/#/R-SSC-8932275 METTL22 transfers 3xCH3 from 3xAdoMet to KIN IEA Sus scrofa A0A287AMY7 R-SSC-204392 https://reactome.org/PathwayBrowser/#/R-SSC-204392 Basigin binds MCT1, MCT3 and MCT4 IEA Sus scrofa A0A287AMY7 R-SSC-373867 https://reactome.org/PathwayBrowser/#/R-SSC-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Sus scrofa A0A287AMY7 R-SSC-373875 https://reactome.org/PathwayBrowser/#/R-SSC-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Sus scrofa A0A287AMY7 R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa A0A287AMY9 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AN07 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa A0A287AN07 R-SSC-420489 https://reactome.org/PathwayBrowser/#/R-SSC-420489 Parathyroid hormone receptor can bind parathyroid hormone IEA Sus scrofa A0A287AN09 R-SSC-166041 https://reactome.org/PathwayBrowser/#/R-SSC-166041 Transfer of LPS onto TLR4 IEA Sus scrofa A0A287AN19 R-SSC-6809521 https://reactome.org/PathwayBrowser/#/R-SSC-6809521 BPIF binds bacteria IEA Sus scrofa A0A287AN25 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287AN33 R-SSC-390593 https://reactome.org/PathwayBrowser/#/R-SSC-390593 ATP Hydrolysis By Myosin IEA Sus scrofa A0A287AN33 R-SSC-390595 https://reactome.org/PathwayBrowser/#/R-SSC-390595 Calcium Binds Troponin-C IEA Sus scrofa A0A287AN33 R-SSC-390597 https://reactome.org/PathwayBrowser/#/R-SSC-390597 Release Of ADP From Myosin IEA Sus scrofa A0A287AN33 R-SSC-390598 https://reactome.org/PathwayBrowser/#/R-SSC-390598 Myosin Binds ATP IEA Sus scrofa A0A287AN33 R-SSC-445699 https://reactome.org/PathwayBrowser/#/R-SSC-445699 ATP Hydrolysis By Myosin IEA Sus scrofa A0A287AN33 R-SSC-445700 https://reactome.org/PathwayBrowser/#/R-SSC-445700 Myosin Binds ATP IEA Sus scrofa A0A287AN33 R-SSC-445704 https://reactome.org/PathwayBrowser/#/R-SSC-445704 Calcium Binds Caldesmon IEA Sus scrofa A0A287AN33 R-SSC-445705 https://reactome.org/PathwayBrowser/#/R-SSC-445705 Release Of ADP From Myosin IEA Sus scrofa A0A287AN34 R-SSC-448955 https://reactome.org/PathwayBrowser/#/R-SSC-448955 Phosphorylation of MEF2 proteins by p38 IEA Sus scrofa A0A287AN34 R-SSC-448963 https://reactome.org/PathwayBrowser/#/R-SSC-448963 Interaction of MyoD:E protein with MEF2 IEA Sus scrofa A0A287AN35 R-SSC-5683714 https://reactome.org/PathwayBrowser/#/R-SSC-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Sus scrofa A0A287AN56 R-SSC-109636 https://reactome.org/PathwayBrowser/#/R-SSC-109636 Recognition and Binding of Core Promoter Elements by TFIID IEA Sus scrofa A0A287AN56 R-SSC-109637 https://reactome.org/PathwayBrowser/#/R-SSC-109637 Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex IEA Sus scrofa A0A287AN56 R-SSC-109638 https://reactome.org/PathwayBrowser/#/R-SSC-109638 Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex IEA Sus scrofa A0A287AN56 R-SSC-109639 https://reactome.org/PathwayBrowser/#/R-SSC-109639 Formation of the closed pre-initiation complex IEA Sus scrofa A0A287AN56 R-SSC-6805399 https://reactome.org/PathwayBrowser/#/R-SSC-6805399 TAF1 phosphorylates TP53 IEA Sus scrofa A0A287AN56 R-SSC-73946 https://reactome.org/PathwayBrowser/#/R-SSC-73946 Abortive initiation after formation of the first phosphodiester bond IEA Sus scrofa A0A287AN56 R-SSC-75095 https://reactome.org/PathwayBrowser/#/R-SSC-75095 Binding of TFIIE to the growing preinitiation complex IEA Sus scrofa A0A287AN56 R-SSC-75850 https://reactome.org/PathwayBrowser/#/R-SSC-75850 Addition of the third nucleotide on the nascent transcript IEA Sus scrofa A0A287AN56 R-SSC-75856 https://reactome.org/PathwayBrowser/#/R-SSC-75856 Abortive Initiation Before Second Transition IEA Sus scrofa A0A287AN56 R-SSC-75861 https://reactome.org/PathwayBrowser/#/R-SSC-75861 NTP Binds Active Site of RNA Polymerase II IEA Sus scrofa A0A287AN56 R-SSC-75862 https://reactome.org/PathwayBrowser/#/R-SSC-75862 Fall Back to Closed Pre-initiation Complex IEA Sus scrofa A0A287AN56 R-SSC-75864 https://reactome.org/PathwayBrowser/#/R-SSC-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Sus scrofa A0A287AN56 R-SSC-75866 https://reactome.org/PathwayBrowser/#/R-SSC-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Sus scrofa A0A287AN56 R-SSC-75869 https://reactome.org/PathwayBrowser/#/R-SSC-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Sus scrofa A0A287AN56 R-SSC-75873 https://reactome.org/PathwayBrowser/#/R-SSC-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Sus scrofa A0A287AN56 R-SSC-75949 https://reactome.org/PathwayBrowser/#/R-SSC-75949 RNA Polymerase II Promoter Opening: First Transition IEA Sus scrofa A0A287AN56 R-SSC-9613494 https://reactome.org/PathwayBrowser/#/R-SSC-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Sus scrofa A0A287AN56 R-SSC-9613497 https://reactome.org/PathwayBrowser/#/R-SSC-9613497 Unwinding DNA for the nascent transcript IEA Sus scrofa A0A287AN57 R-SSC-5229283 https://reactome.org/PathwayBrowser/#/R-SSC-5229283 LCNs bind lipids IEA Sus scrofa A0A287AN69 R-SSC-3769401 https://reactome.org/PathwayBrowser/#/R-SSC-3769401 DKK and KRM bind LRP5/6 IEA Sus scrofa A0A287AN69 R-SSC-5368586 https://reactome.org/PathwayBrowser/#/R-SSC-5368586 DKK promotes clathrin-dependent internalization of LRP6 IEA Sus scrofa A0A287ANC0 R-SSC-8940388 https://reactome.org/PathwayBrowser/#/R-SSC-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Sus scrofa A0A287AND0 R-SSC-8938108 https://reactome.org/PathwayBrowser/#/R-SSC-8938108 SERPINB13 binds cathepsin L IEA Sus scrofa A0A287AND0 R-SSC-8938121 https://reactome.org/PathwayBrowser/#/R-SSC-8938121 SERPINB13 binds CTSK IEA Sus scrofa A0A287AND7 R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa A0A287AND7 R-SSC-9709406 https://reactome.org/PathwayBrowser/#/R-SSC-9709406 CO binds to Cytochrome c oxidase IEA Sus scrofa A0A287AND7 R-SSC-9865663 https://reactome.org/PathwayBrowser/#/R-SSC-9865663 MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex IEA Sus scrofa A0A287ANF5 R-SSC-114256 https://reactome.org/PathwayBrowser/#/R-SSC-114256 CYCS:APAF1 binds procaspase-9 IEA Sus scrofa A0A287ANF5 R-SSC-6805507 https://reactome.org/PathwayBrowser/#/R-SSC-6805507 APAF1 binds AVEN IEA Sus scrofa A0A287ANF9 R-SSC-140355 https://reactome.org/PathwayBrowser/#/R-SSC-140355 Arachidonate is oxidised to PGG2 by PTGS1 IEA Sus scrofa A0A287ANF9 R-SSC-140359 https://reactome.org/PathwayBrowser/#/R-SSC-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Sus scrofa A0A287ANF9 R-SSC-2314678 https://reactome.org/PathwayBrowser/#/R-SSC-2314678 ASA- acetylates PTGS1 IEA Sus scrofa A0A287ANF9 R-SSC-9677320 https://reactome.org/PathwayBrowser/#/R-SSC-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Sus scrofa A0A287ANF9 R-SSC-9716838 https://reactome.org/PathwayBrowser/#/R-SSC-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Sus scrofa A0A287ANI1 R-SSC-418582 https://reactome.org/PathwayBrowser/#/R-SSC-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Sus scrofa A0A287ANI2 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287ANJ7 R-SSC-6805205 https://reactome.org/PathwayBrowser/#/R-SSC-6805205 GPR35 binds kynurenic acid IEA Sus scrofa A0A287ANJ9 R-SSC-9033232 https://reactome.org/PathwayBrowser/#/R-SSC-9033232 PEX7 binds cargo proteins containing PTS2 IEA Sus scrofa A0A287ANJ9 R-SSC-9033485 https://reactome.org/PathwayBrowser/#/R-SSC-9033485 PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 IEA Sus scrofa A0A287ANJ9 R-SSC-9033499 https://reactome.org/PathwayBrowser/#/R-SSC-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Sus scrofa A0A287ANJ9 R-SSC-9033514 https://reactome.org/PathwayBrowser/#/R-SSC-9033514 Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A287ANJ9 R-SSC-9033516 https://reactome.org/PathwayBrowser/#/R-SSC-9033516 PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Sus scrofa A0A287ANJ9 R-SSC-9033527 https://reactome.org/PathwayBrowser/#/R-SSC-9033527 PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 IEA Sus scrofa A0A287ANK4 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A287ANK4 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A287ANK4 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A287ANK4 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A287ANK4 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287ANK4 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287ANK4 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287ANK4 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287ANK4 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287ANK4 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287ANK4 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A287ANK4 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A287ANK4 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A287ANK4 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A287ANK4 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287ANN1 R-SSC-5173005 https://reactome.org/PathwayBrowser/#/R-SSC-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Sus scrofa A0A287ANN1 R-SSC-5173192 https://reactome.org/PathwayBrowser/#/R-SSC-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Sus scrofa A0A287ANR3 R-SSC-3928578 https://reactome.org/PathwayBrowser/#/R-SSC-3928578 EPH receptors autophosphorylate IEA Sus scrofa A0A287ANR3 R-SSC-3928591 https://reactome.org/PathwayBrowser/#/R-SSC-3928591 EPH:EFN tetramers oligomerise IEA Sus scrofa A0A287ANR3 R-SSC-3928597 https://reactome.org/PathwayBrowser/#/R-SSC-3928597 EPH:EFN dimers tetramerise IEA Sus scrofa A0A287ANR3 R-SSC-3928604 https://reactome.org/PathwayBrowser/#/R-SSC-3928604 SFKs phosphorylate VAV2,3 IEA Sus scrofa A0A287ANR3 R-SSC-3928607 https://reactome.org/PathwayBrowser/#/R-SSC-3928607 p-EPHs bind VAV2,3 IEA Sus scrofa A0A287ANR3 R-SSC-3928628 https://reactome.org/PathwayBrowser/#/R-SSC-3928628 VAV exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa A0A287ANR3 R-SSC-3928642 https://reactome.org/PathwayBrowser/#/R-SSC-3928642 TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa A0A287ANR3 R-SSC-3928646 https://reactome.org/PathwayBrowser/#/R-SSC-3928646 EPHAs bind EFNAs IEA Sus scrofa A0A287ANR3 R-SSC-3928651 https://reactome.org/PathwayBrowser/#/R-SSC-3928651 NGEF exchanges GTP for GDP on RHOA IEA Sus scrofa A0A287ANR3 R-SSC-4093327 https://reactome.org/PathwayBrowser/#/R-SSC-4093327 EPHA binds TIAM1 IEA Sus scrofa A0A287ANS1 R-SSC-3827958 https://reactome.org/PathwayBrowser/#/R-SSC-3827958 E-cadherin degradation by MMP9, KLK7 IEA Sus scrofa A0A287ANS6 R-SSC-212222 https://reactome.org/PathwayBrowser/#/R-SSC-212222 PRC2 recruits DNA methyltransferases IEA Sus scrofa A0A287ANS6 R-SSC-212252 https://reactome.org/PathwayBrowser/#/R-SSC-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Sus scrofa A0A287ANS6 R-SSC-212263 https://reactome.org/PathwayBrowser/#/R-SSC-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Sus scrofa A0A287ANS6 R-SSC-212269 https://reactome.org/PathwayBrowser/#/R-SSC-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Sus scrofa A0A287ANS6 R-SSC-2172678 https://reactome.org/PathwayBrowser/#/R-SSC-2172678 PHF8 demethylates histone H4K20me1 IEA Sus scrofa A0A287ANS6 R-SSC-2294580 https://reactome.org/PathwayBrowser/#/R-SSC-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Sus scrofa A0A287ANS6 R-SSC-2294590 https://reactome.org/PathwayBrowser/#/R-SSC-2294590 PLK1 binds phosphorylated condensin II complex IEA Sus scrofa A0A287ANS6 R-SSC-2294600 https://reactome.org/PathwayBrowser/#/R-SSC-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Sus scrofa A0A287ANS6 R-SSC-2301205 https://reactome.org/PathwayBrowser/#/R-SSC-2301205 SETD8 monomethylates histone H4 IEA Sus scrofa A0A287ANS6 R-SSC-3222593 https://reactome.org/PathwayBrowser/#/R-SSC-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Sus scrofa A0A287ANS6 R-SSC-3229089 https://reactome.org/PathwayBrowser/#/R-SSC-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Sus scrofa A0A287ANS6 R-SSC-3229102 https://reactome.org/PathwayBrowser/#/R-SSC-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Sus scrofa A0A287ANS6 R-SSC-3240295 https://reactome.org/PathwayBrowser/#/R-SSC-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Sus scrofa A0A287ANS6 R-SSC-3785711 https://reactome.org/PathwayBrowser/#/R-SSC-3785711 Telomere shortening during replicative exhaustion IEA Sus scrofa A0A287ANS6 R-SSC-3788745 https://reactome.org/PathwayBrowser/#/R-SSC-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Sus scrofa A0A287ANS6 R-SSC-3788748 https://reactome.org/PathwayBrowser/#/R-SSC-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Sus scrofa A0A287ANS6 R-SSC-427337 https://reactome.org/PathwayBrowser/#/R-SSC-427337 MBD2 binds methylcytosine in chromatin IEA Sus scrofa A0A287ANS6 R-SSC-427514 https://reactome.org/PathwayBrowser/#/R-SSC-427514 eNoSC deacetylates histone H3 IEA Sus scrofa A0A287ANS6 R-SSC-427527 https://reactome.org/PathwayBrowser/#/R-SSC-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Sus scrofa A0A287ANS6 R-SSC-427528 https://reactome.org/PathwayBrowser/#/R-SSC-427528 Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) IEA Sus scrofa A0A287ANS6 R-SSC-5216234 https://reactome.org/PathwayBrowser/#/R-SSC-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Sus scrofa A0A287ANS6 R-SSC-5250938 https://reactome.org/PathwayBrowser/#/R-SSC-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Sus scrofa A0A287ANS6 R-SSC-5578742 https://reactome.org/PathwayBrowser/#/R-SSC-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Sus scrofa A0A287ANS6 R-SSC-5625774 https://reactome.org/PathwayBrowser/#/R-SSC-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Sus scrofa A0A287ANS6 R-SSC-5625784 https://reactome.org/PathwayBrowser/#/R-SSC-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Sus scrofa A0A287ANS6 R-SSC-5625796 https://reactome.org/PathwayBrowser/#/R-SSC-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Sus scrofa A0A287ANS6 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa A0A287ANS6 R-SSC-5625848 https://reactome.org/PathwayBrowser/#/R-SSC-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa A0A287ANS6 R-SSC-5625849 https://reactome.org/PathwayBrowser/#/R-SSC-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Sus scrofa A0A287ANS6 R-SSC-5625870 https://reactome.org/PathwayBrowser/#/R-SSC-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa A0A287ANS6 R-SSC-606287 https://reactome.org/PathwayBrowser/#/R-SSC-606287 RSF complex binds the centromere IEA Sus scrofa A0A287ANS6 R-SSC-73718 https://reactome.org/PathwayBrowser/#/R-SSC-73718 UBF-1 Binds rDNA Promoter IEA Sus scrofa A0A287ANS6 R-SSC-74986 https://reactome.org/PathwayBrowser/#/R-SSC-74986 Elongation of pre-rRNA transcript IEA Sus scrofa A0A287ANS6 R-SSC-8936481 https://reactome.org/PathwayBrowser/#/R-SSC-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Sus scrofa A0A287ANS6 R-SSC-8936584 https://reactome.org/PathwayBrowser/#/R-SSC-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Sus scrofa A0A287ANS6 R-SSC-8936608 https://reactome.org/PathwayBrowser/#/R-SSC-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Sus scrofa A0A287ANS6 R-SSC-8936621 https://reactome.org/PathwayBrowser/#/R-SSC-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Sus scrofa A0A287ANS6 R-SSC-8937016 https://reactome.org/PathwayBrowser/#/R-SSC-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Sus scrofa A0A287ANS6 R-SSC-8937022 https://reactome.org/PathwayBrowser/#/R-SSC-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Sus scrofa A0A287ANS6 R-SSC-8937050 https://reactome.org/PathwayBrowser/#/R-SSC-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Sus scrofa A0A287ANS6 R-SSC-8937113 https://reactome.org/PathwayBrowser/#/R-SSC-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Sus scrofa A0A287ANS6 R-SSC-9009065 https://reactome.org/PathwayBrowser/#/R-SSC-9009065 FOXA1 and GATA3 bind to CCND1 promoter IEA Sus scrofa A0A287ANS6 R-SSC-9009371 https://reactome.org/PathwayBrowser/#/R-SSC-9009371 Binding of AP1 transcriptional activator complexes to CCND1 promoter IEA Sus scrofa A0A287ANS6 R-SSC-9011949 https://reactome.org/PathwayBrowser/#/R-SSC-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Sus scrofa A0A287ANS6 R-SSC-9011952 https://reactome.org/PathwayBrowser/#/R-SSC-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Sus scrofa A0A287ANS6 R-SSC-9011983 https://reactome.org/PathwayBrowser/#/R-SSC-9011983 Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes IEA Sus scrofa A0A287ANS6 R-SSC-9012000 https://reactome.org/PathwayBrowser/#/R-SSC-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Sus scrofa A0A287ANS6 R-SSC-9629195 https://reactome.org/PathwayBrowser/#/R-SSC-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA IEA Sus scrofa A0A287ANS6 R-SSC-9629216 https://reactome.org/PathwayBrowser/#/R-SSC-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Sus scrofa A0A287ANS6 R-SSC-9670101 https://reactome.org/PathwayBrowser/#/R-SSC-9670101 ATRX:DAXX binds to subtelomeric chromosomal regions IEA Sus scrofa A0A287ANS6 R-SSC-9749197 https://reactome.org/PathwayBrowser/#/R-SSC-9749197 ORC1 binds to H4K20me2 IEA Sus scrofa A0A287ANS6 R-SSC-9842833 https://reactome.org/PathwayBrowser/#/R-SSC-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Sus scrofa A0A287ANS6 R-SSC-9843115 https://reactome.org/PathwayBrowser/#/R-SSC-9843115 Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci IEA Sus scrofa A0A287ANS6 R-SSC-9843117 https://reactome.org/PathwayBrowser/#/R-SSC-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Sus scrofa A0A287ANS6 R-SSC-9843118 https://reactome.org/PathwayBrowser/#/R-SSC-9843118 RXRA binds ligands IEA Sus scrofa A0A287ANS6 R-SSC-9843120 https://reactome.org/PathwayBrowser/#/R-SSC-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Sus scrofa A0A287ANS6 R-SSC-9844006 https://reactome.org/PathwayBrowser/#/R-SSC-9844006 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) IEA Sus scrofa A0A287ANS6 R-SSC-9844057 https://reactome.org/PathwayBrowser/#/R-SSC-9844057 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome IEA Sus scrofa A0A287ANT3 R-SSC-5683831 https://reactome.org/PathwayBrowser/#/R-SSC-5683831 CCDC59 binds TTF1 IEA Sus scrofa A0A287ANU3 R-SSC-448958 https://reactome.org/PathwayBrowser/#/R-SSC-448958 Nuclear translocation of p38 MAPK IEA Sus scrofa A0A287ANU4 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A287ANU4 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A287ANU4 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A287ANU4 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A287ANU4 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A287ANU5 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287ANU5 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287ANU5 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287ANU5 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287ANU5 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287ANU5 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287ANU5 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287ANU5 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287ANU5 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287ANU5 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287ANU5 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287ANU5 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287ANU5 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287ANU5 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287ANU5 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287ANU5 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287ANU5 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287ANU5 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287ANU5 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287ANU5 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287ANU5 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287ANU5 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287ANU5 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287ANU5 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287ANU5 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287ANU5 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287ANU5 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287ANU5 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287ANU5 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287ANU5 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287ANU5 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287ANU5 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287ANU5 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287ANU5 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287ANU5 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287ANU5 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287ANU5 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287ANU5 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287ANU5 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287ANU5 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287ANU5 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287ANU5 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287ANU5 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287ANU5 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287ANU5 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287ANU5 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287ANU5 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287ANV0 R-SSC-8856808 https://reactome.org/PathwayBrowser/#/R-SSC-8856808 Recruitment of AP-2 complex and clathrin IEA Sus scrofa A0A287ANV0 R-SSC-8856813 https://reactome.org/PathwayBrowser/#/R-SSC-8856813 AAK1 phosphorylates AP-2 mu subunit at T156 IEA Sus scrofa A0A287ANV0 R-SSC-8866283 https://reactome.org/PathwayBrowser/#/R-SSC-8866283 ARBB recruits GPCRs into clathrin-coated pits IEA Sus scrofa A0A287ANV0 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A287ANV0 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A287ANV0 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A287ANV0 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A287ANW9 R-SSC-5694409 https://reactome.org/PathwayBrowser/#/R-SSC-5694409 Nucleotide exchange on RAB1 IEA Sus scrofa A0A287ANW9 R-SSC-5694418 https://reactome.org/PathwayBrowser/#/R-SSC-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Sus scrofa A0A287ANY2 R-SSC-5685607 https://reactome.org/PathwayBrowser/#/R-SSC-5685607 Sialic acid binds SIGLEC IEA Sus scrofa A0A287ANY2 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A287AP08 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A287AP08 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287AP23 R-SSC-3371353 https://reactome.org/PathwayBrowser/#/R-SSC-3371353 Soluble TNF-α binds TNFR1 IEA Sus scrofa A0A287AP23 R-SSC-5252079 https://reactome.org/PathwayBrowser/#/R-SSC-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Sus scrofa A0A287AP23 R-SSC-83660 https://reactome.org/PathwayBrowser/#/R-SSC-83660 Membrane-anchored TNF-α binds TNFR1 IEA Sus scrofa A0A287AP28 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287AP28 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287AP28 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287AP28 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287AP28 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287AP28 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287AP28 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287AP28 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287AP28 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287AP28 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AP28 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287AP28 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287AP28 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287AP28 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287AP28 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287AP28 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287AP28 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287AP28 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287AP28 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287AP28 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287AP28 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287AP28 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287AP28 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287AP28 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287AP28 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287AP28 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287AP28 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287AP28 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287AP28 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287AP28 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287AP28 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287AP28 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287AP28 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287AP28 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287AP28 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287AP28 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287AP28 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287AP28 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287AP28 R-SSC-8858498 https://reactome.org/PathwayBrowser/#/R-SSC-8858498 SL (surrogate light chain) binds IgH to form pre-BCR IEA Sus scrofa A0A287AP28 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287AP28 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287AP28 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287AP28 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287AP28 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287AP28 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287AP28 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287AP28 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287AP28 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287AP37 R-SSC-6814086 https://reactome.org/PathwayBrowser/#/R-SSC-6814086 ARFRP1 recruits ARL1 to the TGN IEA Sus scrofa A0A287AP37 R-SSC-6814088 https://reactome.org/PathwayBrowser/#/R-SSC-6814088 SYS1 binds AcM-ARFRP1 IEA Sus scrofa A0A287AP37 R-SSC-6814091 https://reactome.org/PathwayBrowser/#/R-SSC-6814091 ARL1 recruits TGN Golgin homodimers IEA Sus scrofa A0A287AP38 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287AP43 R-SSC-5696914 https://reactome.org/PathwayBrowser/#/R-SSC-5696914 USP28 deubiquitinates CLSPN and MYC IEA Sus scrofa A0A287AP59 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AP64 R-SSC-77319 https://reactome.org/PathwayBrowser/#/R-SSC-77319 Butanoyl-CoA+FAD<=>Crotonoyl-CoA+FADH2 IEA Sus scrofa A0A287AP64 R-SSC-77327 https://reactome.org/PathwayBrowser/#/R-SSC-77327 Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 IEA Sus scrofa A0A287AP69 R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa A0A287AP69 R-SSC-9679787 https://reactome.org/PathwayBrowser/#/R-SSC-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Sus scrofa A0A287AP69 R-SSC-996727 https://reactome.org/PathwayBrowser/#/R-SSC-996727 REST recruits the BHC complex IEA Sus scrofa A0A287AP76 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287AP77 R-SSC-917696 https://reactome.org/PathwayBrowser/#/R-SSC-917696 Cargo Sequestration IEA Sus scrofa A0A287AP77 R-SSC-917730 https://reactome.org/PathwayBrowser/#/R-SSC-917730 Cargo Recognition And Sorting IEA Sus scrofa A0A287AP94 R-SSC-162683 https://reactome.org/PathwayBrowser/#/R-SSC-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH IEA Sus scrofa A0A287APA2 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287APA5 R-SSC-6797553 https://reactome.org/PathwayBrowser/#/R-SSC-6797553 Protein 4.1 binds CASK IEA Sus scrofa A0A287APA5 R-SSC-6797568 https://reactome.org/PathwayBrowser/#/R-SSC-6797568 NRXNs bind CASK:Protein 4.1 IEA Sus scrofa A0A287APB4 R-SSC-113503 https://reactome.org/PathwayBrowser/#/R-SSC-113503 PP2A mediated localization of RB1 protein in chromatin IEA Sus scrofa A0A287APB4 R-SSC-1363274 https://reactome.org/PathwayBrowser/#/R-SSC-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Sus scrofa A0A287APB4 R-SSC-1363276 https://reactome.org/PathwayBrowser/#/R-SSC-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Sus scrofa A0A287APB4 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A287APB4 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A287APB4 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A287APB4 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A287APB4 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287APB4 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287APB4 R-SSC-195251 https://reactome.org/PathwayBrowser/#/R-SSC-195251 Assembly of the destruction complex IEA Sus scrofa A0A287APB4 R-SSC-195275 https://reactome.org/PathwayBrowser/#/R-SSC-195275 Phosphorylation of APC component of the destruction complex IEA Sus scrofa A0A287APB4 R-SSC-195280 https://reactome.org/PathwayBrowser/#/R-SSC-195280 Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex IEA Sus scrofa A0A287APB4 R-SSC-195283 https://reactome.org/PathwayBrowser/#/R-SSC-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Sus scrofa A0A287APB4 R-SSC-195287 https://reactome.org/PathwayBrowser/#/R-SSC-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Sus scrofa A0A287APB4 R-SSC-195300 https://reactome.org/PathwayBrowser/#/R-SSC-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Sus scrofa A0A287APB4 R-SSC-195304 https://reactome.org/PathwayBrowser/#/R-SSC-195304 Association of beta-catenin with the destruction complex IEA Sus scrofa A0A287APB4 R-SSC-195318 https://reactome.org/PathwayBrowser/#/R-SSC-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Sus scrofa A0A287APB4 R-SSC-199959 https://reactome.org/PathwayBrowser/#/R-SSC-199959 ERKs are inactivated by protein phosphatase 2A IEA Sus scrofa A0A287APB4 R-SSC-201685 https://reactome.org/PathwayBrowser/#/R-SSC-201685 Beta-catenin is released from the destruction complex IEA Sus scrofa A0A287APB4 R-SSC-201790 https://reactome.org/PathwayBrowser/#/R-SSC-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Sus scrofa A0A287APB4 R-SSC-2130279 https://reactome.org/PathwayBrowser/#/R-SSC-2130279 Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex IEA Sus scrofa A0A287APB4 R-SSC-2130282 https://reactome.org/PathwayBrowser/#/R-SSC-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Sus scrofa A0A287APB4 R-SSC-2130286 https://reactome.org/PathwayBrowser/#/R-SSC-2130286 Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) IEA Sus scrofa A0A287APB4 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287APB4 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287APB4 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287APB4 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287APB4 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A287APB4 R-SSC-388808 https://reactome.org/PathwayBrowser/#/R-SSC-388808 CD28 homodimer binds B7-2 monomer IEA Sus scrofa A0A287APB4 R-SSC-388809 https://reactome.org/PathwayBrowser/#/R-SSC-388809 CTLA-4 binds B7-1/B7-2 IEA Sus scrofa A0A287APB4 R-SSC-388811 https://reactome.org/PathwayBrowser/#/R-SSC-388811 CD28 homodimer binds B7-1 homodimer IEA Sus scrofa A0A287APB4 R-SSC-388833 https://reactome.org/PathwayBrowser/#/R-SSC-388833 Phosphorylation of CTLA-4 IEA Sus scrofa A0A287APB4 R-SSC-389532 https://reactome.org/PathwayBrowser/#/R-SSC-389532 PP2A binds CTLA4 dimer IEA Sus scrofa A0A287APB4 R-SSC-4088141 https://reactome.org/PathwayBrowser/#/R-SSC-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Sus scrofa A0A287APB4 R-SSC-432143 https://reactome.org/PathwayBrowser/#/R-SSC-432143 PECAM-1 binds PP2A IEA Sus scrofa A0A287APB4 R-SSC-5229343 https://reactome.org/PathwayBrowser/#/R-SSC-5229343 AXIN is phosphorylated in the destruction complex IEA Sus scrofa A0A287APB4 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A287APB4 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A287APB4 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A287APB4 R-SSC-5672957 https://reactome.org/PathwayBrowser/#/R-SSC-5672957 PP2A dephosphorylates KSR1 IEA Sus scrofa A0A287APB4 R-SSC-5672961 https://reactome.org/PathwayBrowser/#/R-SSC-5672961 PP2A dephosphorylates inactive RAFs IEA Sus scrofa A0A287APB4 R-SSC-5675431 https://reactome.org/PathwayBrowser/#/R-SSC-5675431 PP2A dephosphorylates RAF1 IEA Sus scrofa A0A287APB4 R-SSC-6792863 https://reactome.org/PathwayBrowser/#/R-SSC-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Sus scrofa A0A287APB4 R-SSC-6792871 https://reactome.org/PathwayBrowser/#/R-SSC-6792871 CCNG1 recruits PP2A-PPP2R5C to MDM2 IEA Sus scrofa A0A287APB4 R-SSC-6811454 https://reactome.org/PathwayBrowser/#/R-SSC-6811454 MAPKs phosphorylate PP2A IEA Sus scrofa A0A287APB4 R-SSC-6811472 https://reactome.org/PathwayBrowser/#/R-SSC-6811472 IER3 recruits MAPKs to PP2A-B56-beta,gamma IEA Sus scrofa A0A287APB4 R-SSC-8856945 https://reactome.org/PathwayBrowser/#/R-SSC-8856945 PP2A methylation by LCMT1 IEA Sus scrofa A0A287APB4 R-SSC-8856951 https://reactome.org/PathwayBrowser/#/R-SSC-8856951 PP2A demethylation by PPME1 IEA Sus scrofa A0A287APB4 R-SSC-8857925 https://reactome.org/PathwayBrowser/#/R-SSC-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Sus scrofa A0A287APB4 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287APB4 R-SSC-9836664 https://reactome.org/PathwayBrowser/#/R-SSC-9836664 p-PKR dimer phosphorylates PPP2R5A IEA Sus scrofa A0A287APB4 R-SSC-9865226 https://reactome.org/PathwayBrowser/#/R-SSC-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Sus scrofa A0A287APC7 R-SSC-418309 https://reactome.org/PathwayBrowser/#/R-SSC-418309 ATP2B1-4 transport cytosolic Ca2+ to extracellular region IEA Sus scrofa A0A287APC7 R-SSC-5617178 https://reactome.org/PathwayBrowser/#/R-SSC-5617178 ATP2B4 binds to NOS1, inhibiting it IEA Sus scrofa A0A287APC7 R-SSC-5617179 https://reactome.org/PathwayBrowser/#/R-SSC-5617179 PRKACA phosphorylates TNNI3 IEA Sus scrofa A0A287APC7 R-SSC-5617182 https://reactome.org/PathwayBrowser/#/R-SSC-5617182 PRKACA phosphorylates PLN IEA Sus scrofa A0A287APD0 R-SSC-3769401 https://reactome.org/PathwayBrowser/#/R-SSC-3769401 DKK and KRM bind LRP5/6 IEA Sus scrofa A0A287APD0 R-SSC-5368586 https://reactome.org/PathwayBrowser/#/R-SSC-5368586 DKK promotes clathrin-dependent internalization of LRP6 IEA Sus scrofa A0A287APD7 R-SSC-3769397 https://reactome.org/PathwayBrowser/#/R-SSC-3769397 SOST binds LRP5/6 IEA Sus scrofa A0A287APG0 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa A0A287APG0 R-SSC-9013024 https://reactome.org/PathwayBrowser/#/R-SSC-9013024 RHOB binds effectors at the plasma membrane IEA Sus scrofa A0A287APG0 R-SSC-9013110 https://reactome.org/PathwayBrowser/#/R-SSC-9013110 RHOC binds effectors at the plasma membrane IEA Sus scrofa A0A287APG1 R-SSC-2022403 https://reactome.org/PathwayBrowser/#/R-SSC-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Sus scrofa A0A287APG1 R-SSC-2022412 https://reactome.org/PathwayBrowser/#/R-SSC-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Sus scrofa A0A287APG1 R-SSC-2065357 https://reactome.org/PathwayBrowser/#/R-SSC-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Sus scrofa A0A287APG2 R-SSC-1296037 https://reactome.org/PathwayBrowser/#/R-SSC-1296037 Activation of Ca2+ activated Potassium channels with large conductance IEA Sus scrofa A0A287APG4 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287APG4 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287APG4 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287APG4 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287APG4 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287APG4 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287APG4 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287APG4 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287APG4 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287APG4 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287APG4 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287APG4 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287APG4 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287APG4 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287APG4 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287APG4 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287APG4 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287APG4 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287APG4 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287APG4 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287APG4 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287APG4 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287APG4 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287APG4 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287APG4 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287APG4 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287APG4 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287APG4 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287APG4 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287APG4 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287APG4 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287APG4 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287APG4 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287APG4 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287APG4 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287APG4 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287APG4 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287APG4 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287APG4 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287APG4 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287APG4 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287APG4 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287APG4 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287APG4 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287APG4 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287APG4 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287APG4 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287API4 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287APJ6 R-SSC-114352 https://reactome.org/PathwayBrowser/#/R-SSC-114352 Sequestration of tBID by BCL-2 IEA Sus scrofa A0A287APJ6 R-SSC-139897 https://reactome.org/PathwayBrowser/#/R-SSC-139897 BAD displaces tBID from BCL-2 sequestration IEA Sus scrofa A0A287APJ6 R-SSC-508163 https://reactome.org/PathwayBrowser/#/R-SSC-508163 BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 IEA Sus scrofa A0A287APJ6 R-SSC-9692376 https://reactome.org/PathwayBrowser/#/R-SSC-9692376 BCL2 binds BCL2 antagonists IEA Sus scrofa A0A287APL3 R-SSC-2032781 https://reactome.org/PathwayBrowser/#/R-SSC-2032781 WWTR1 (TAZ) binds TEAD IEA Sus scrofa A0A287APL3 R-SSC-8871260 https://reactome.org/PathwayBrowser/#/R-SSC-8871260 YAP1 binds TEAD2 IEA Sus scrofa A0A287APL3 R-SSC-8951676 https://reactome.org/PathwayBrowser/#/R-SSC-8951676 RUNX3 binds TEADs and YAP1 IEA Sus scrofa A0A287APL8 R-SSC-5694423 https://reactome.org/PathwayBrowser/#/R-SSC-5694423 NSF and SNAPs bind cis-SNARE complex IEA Sus scrofa A0A287APL8 R-SSC-5694425 https://reactome.org/PathwayBrowser/#/R-SSC-5694425 NSF ATPase activity dissociates cis-SNARE IEA Sus scrofa A0A287APL8 R-SSC-5694446 https://reactome.org/PathwayBrowser/#/R-SSC-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle IEA Sus scrofa A0A287APL8 R-SSC-6807875 https://reactome.org/PathwayBrowser/#/R-SSC-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Sus scrofa A0A287APL8 R-SSC-6807877 https://reactome.org/PathwayBrowser/#/R-SSC-6807877 ARFGAPs stimulate ARF GTPase activity IEA Sus scrofa A0A287APL8 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa A0A287APL8 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A287APL8 R-SSC-6809011 https://reactome.org/PathwayBrowser/#/R-SSC-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Sus scrofa A0A287APL8 R-SSC-6809014 https://reactome.org/PathwayBrowser/#/R-SSC-6809014 cis-Golgi cis-SNARE binds NSF and SNAPs IEA Sus scrofa A0A287APL8 R-SSC-6809015 https://reactome.org/PathwayBrowser/#/R-SSC-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi IEA Sus scrofa A0A287APM5 R-SSC-168053 https://reactome.org/PathwayBrowser/#/R-SSC-168053 Phosphorylated MAPKs phosphorylate ATF-2 IEA Sus scrofa A0A287APM5 R-SSC-168136 https://reactome.org/PathwayBrowser/#/R-SSC-168136 Activated JNKs phosphorylate c-JUN IEA Sus scrofa A0A287APM5 R-SSC-168162 https://reactome.org/PathwayBrowser/#/R-SSC-168162 Phosphorylation of human JNKs by activated MKK4/MKK7 IEA Sus scrofa A0A287APM5 R-SSC-450348 https://reactome.org/PathwayBrowser/#/R-SSC-450348 Activated human JNKs migrate to nucleoplasm IEA Sus scrofa A0A287APN4 R-SSC-5173005 https://reactome.org/PathwayBrowser/#/R-SSC-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Sus scrofa A0A287APN4 R-SSC-5173192 https://reactome.org/PathwayBrowser/#/R-SSC-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Sus scrofa A0A287APQ4 R-SSC-159566 https://reactome.org/PathwayBrowser/#/R-SSC-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A IEA Sus scrofa A0A287APQ4 R-SSC-159574 https://reactome.org/PathwayBrowser/#/R-SSC-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA IEA Sus scrofa A0A287APQ4 R-SSC-9750001 https://reactome.org/PathwayBrowser/#/R-SSC-9750001 GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid IEA Sus scrofa A0A287APQ9 R-SSC-8867667 https://reactome.org/PathwayBrowser/#/R-SSC-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Sus scrofa A0A287APR1 R-SSC-156826 https://reactome.org/PathwayBrowser/#/R-SSC-156826 Dissociation of L13a from the 60s ribosomal subunit IEA Sus scrofa A0A287APR1 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A287APR1 R-SSC-6791218 https://reactome.org/PathwayBrowser/#/R-SSC-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Sus scrofa A0A287APR1 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A287APR1 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A287APR1 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A287APR1 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A287APR1 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A287APR1 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A287APR1 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A287APR1 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A287APS6 R-SSC-1296348 https://reactome.org/PathwayBrowser/#/R-SSC-1296348 Activation of TWIK-related K+ channel (TREK) IEA Sus scrofa A0A287APS6 R-SSC-5578910 https://reactome.org/PathwayBrowser/#/R-SSC-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Sus scrofa A0A287APU7 R-SSC-110316 https://reactome.org/PathwayBrowser/#/R-SSC-110316 POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template IEA Sus scrofa A0A287APU7 R-SSC-110317 https://reactome.org/PathwayBrowser/#/R-SSC-110317 Insertion of correct bases opposite the lesion by POLH IEA Sus scrofa A0A287APU7 R-SSC-110319 https://reactome.org/PathwayBrowser/#/R-SSC-110319 Elongation by POLH IEA Sus scrofa A0A287APU7 R-SSC-5653754 https://reactome.org/PathwayBrowser/#/R-SSC-5653754 UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA IEA Sus scrofa A0A287APU7 R-SSC-5653756 https://reactome.org/PathwayBrowser/#/R-SSC-5653756 TRIM25 binds monoUb:164-PCNA IEA Sus scrofa A0A287APU7 R-SSC-5653766 https://reactome.org/PathwayBrowser/#/R-SSC-5653766 USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A287APU7 R-SSC-5653770 https://reactome.org/PathwayBrowser/#/R-SSC-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A287APU7 R-SSC-5654985 https://reactome.org/PathwayBrowser/#/R-SSC-5654985 SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH IEA Sus scrofa A0A287APU7 R-SSC-5654986 https://reactome.org/PathwayBrowser/#/R-SSC-5654986 SPRTN binds monoUb:K164-PCNA associated with POLH IEA Sus scrofa A0A287APU7 R-SSC-5654989 https://reactome.org/PathwayBrowser/#/R-SSC-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Sus scrofa A0A287APU7 R-SSC-5655142 https://reactome.org/PathwayBrowser/#/R-SSC-5655142 RCHY1 binds POLH IEA Sus scrofa A0A287APU7 R-SSC-5655170 https://reactome.org/PathwayBrowser/#/R-SSC-5655170 RCHY1 monoubiquitinates POLH IEA Sus scrofa A0A287APU7 R-SSC-5693593 https://reactome.org/PathwayBrowser/#/R-SSC-5693593 D-loop extension by DNA polymerases IEA Sus scrofa A0A287APU9 R-SSC-199203 https://reactome.org/PathwayBrowser/#/R-SSC-199203 PANK1/3 phosphorylate PanK IEA Sus scrofa A0A287APW7 R-SSC-156808 https://reactome.org/PathwayBrowser/#/R-SSC-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Sus scrofa A0A287APW7 R-SSC-156823 https://reactome.org/PathwayBrowser/#/R-SSC-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Sus scrofa A0A287APW7 R-SSC-157849 https://reactome.org/PathwayBrowser/#/R-SSC-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Sus scrofa A0A287APW7 R-SSC-381111 https://reactome.org/PathwayBrowser/#/R-SSC-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK IEA Sus scrofa A0A287APW7 R-SSC-5227009 https://reactome.org/PathwayBrowser/#/R-SSC-5227009 ABCF1 binds EIF2 IEA Sus scrofa A0A287APW7 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa A0A287APW7 R-SSC-72663 https://reactome.org/PathwayBrowser/#/R-SSC-72663 De novo formation of eIF2:GTP IEA Sus scrofa A0A287APW7 R-SSC-72669 https://reactome.org/PathwayBrowser/#/R-SSC-72669 Met-tRNAi binds to eIF2:GTP to form the ternary complex IEA Sus scrofa A0A287APW7 R-SSC-72670 https://reactome.org/PathwayBrowser/#/R-SSC-72670 Formation of eIF2:GDP:eIF2B intermediate IEA Sus scrofa A0A287APW7 R-SSC-72691 https://reactome.org/PathwayBrowser/#/R-SSC-72691 Formation of the 43S pre-initiation complex IEA Sus scrofa A0A287APW7 R-SSC-72697 https://reactome.org/PathwayBrowser/#/R-SSC-72697 Start codon recognition IEA Sus scrofa A0A287APW7 R-SSC-72722 https://reactome.org/PathwayBrowser/#/R-SSC-72722 eIF2 activation IEA Sus scrofa A0A287APW7 R-SSC-9840415 https://reactome.org/PathwayBrowser/#/R-SSC-9840415 DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) IEA Sus scrofa A0A287APX1 R-SSC-2161620 https://reactome.org/PathwayBrowser/#/R-SSC-2161620 PGH2 is isomerised to PGD2 by PTGDS IEA Sus scrofa A0A287APX2 R-SSC-6814091 https://reactome.org/PathwayBrowser/#/R-SSC-6814091 ARL1 recruits TGN Golgin homodimers IEA Sus scrofa A0A287APX5 R-SSC-6791221 https://reactome.org/PathwayBrowser/#/R-SSC-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA IEA Sus scrofa A0A287APX5 R-SSC-6791222 https://reactome.org/PathwayBrowser/#/R-SSC-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Sus scrofa A0A287APX5 R-SSC-6791227 https://reactome.org/PathwayBrowser/#/R-SSC-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Sus scrofa A0A287APY3 R-SSC-9013144 https://reactome.org/PathwayBrowser/#/R-SSC-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Sus scrofa A0A287APY3 R-SSC-9013161 https://reactome.org/PathwayBrowser/#/R-SSC-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Sus scrofa A0A287APZ2 R-SSC-2029465 https://reactome.org/PathwayBrowser/#/R-SSC-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Sus scrofa A0A287APZ2 R-SSC-2029466 https://reactome.org/PathwayBrowser/#/R-SSC-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Sus scrofa A0A287APZ2 R-SSC-2029469 https://reactome.org/PathwayBrowser/#/R-SSC-2029469 p-ERK phosphorylates WAVEs and ABI IEA Sus scrofa A0A287APZ2 R-SSC-2130194 https://reactome.org/PathwayBrowser/#/R-SSC-2130194 ABL phosphorylates WAVEs IEA Sus scrofa A0A287APZ2 R-SSC-2197690 https://reactome.org/PathwayBrowser/#/R-SSC-2197690 Detachment of WASP/WAVE IEA Sus scrofa A0A287APZ2 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A287APZ2 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa A0A287AQ10 R-SSC-216043 https://reactome.org/PathwayBrowser/#/R-SSC-216043 Collagen type II binds integrin alpha10beta1 IEA Sus scrofa A0A287AQ10 R-SSC-2327695 https://reactome.org/PathwayBrowser/#/R-SSC-2327695 Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 IEA Sus scrofa A0A287AQ10 R-SSC-4084903 https://reactome.org/PathwayBrowser/#/R-SSC-4084903 Collagen types VI, IX bind integrin alpha10beta1 IEA Sus scrofa A0A287AQ18 R-SSC-6805546 https://reactome.org/PathwayBrowser/#/R-SSC-6805546 Keratin type I binds keratin type II IEA Sus scrofa A0A287AQ18 R-SSC-6805573 https://reactome.org/PathwayBrowser/#/R-SSC-6805573 Keratin type I/type II heterodimers form tetramers IEA Sus scrofa A0A287AQ18 R-SSC-6806610 https://reactome.org/PathwayBrowser/#/R-SSC-6806610 Keratin filament formation IEA Sus scrofa A0A287AQ18 R-SSC-6806613 https://reactome.org/PathwayBrowser/#/R-SSC-6806613 Keratin tetramers bind to form unit length filaments IEA Sus scrofa A0A287AQ18 R-SSC-6806629 https://reactome.org/PathwayBrowser/#/R-SSC-6806629 Formation of tonofilament bundles IEA Sus scrofa A0A287AQ18 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A287AQ18 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287AQ18 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A287AQ18 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A287AQ20 R-SSC-3266557 https://reactome.org/PathwayBrowser/#/R-SSC-3266557 Factor I cleaves iC3b IEA Sus scrofa A0A287AQ20 R-SSC-976743 https://reactome.org/PathwayBrowser/#/R-SSC-976743 Factor I inactivates plasma Factor H-bound C3b IEA Sus scrofa A0A287AQ20 R-SSC-976801 https://reactome.org/PathwayBrowser/#/R-SSC-976801 Complement factor I complex formation IEA Sus scrofa A0A287AQ20 R-SSC-976810 https://reactome.org/PathwayBrowser/#/R-SSC-976810 Complement factor I binds to extracellular Factor H:C3b IEA Sus scrofa A0A287AQ20 R-SSC-977359 https://reactome.org/PathwayBrowser/#/R-SSC-977359 Complement factor I binds to membrane-associated Factor H:C3b IEA Sus scrofa A0A287AQ20 R-SSC-977371 https://reactome.org/PathwayBrowser/#/R-SSC-977371 Factor I inactivates Factor H-boundC3b IEA Sus scrofa A0A287AQ20 R-SSC-977602 https://reactome.org/PathwayBrowser/#/R-SSC-977602 Complement factor I binds to MCP, CR1:C4b, C3b IEA Sus scrofa A0A287AQ20 R-SSC-977615 https://reactome.org/PathwayBrowser/#/R-SSC-977615 Factor I inactivates MCP/CR1-bound C4b/C3b IEA Sus scrofa A0A287AQ22 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AQ29 R-SSC-5684875 https://reactome.org/PathwayBrowser/#/R-SSC-5684875 Binding of ATR:ATRIP to RPA at resected DNA DSBs IEA Sus scrofa A0A287AQ29 R-SSC-5684882 https://reactome.org/PathwayBrowser/#/R-SSC-5684882 CHEK1 is recruited to resected DNA DSBs IEA Sus scrofa A0A287AQ29 R-SSC-5684887 https://reactome.org/PathwayBrowser/#/R-SSC-5684887 Activation of CHEK1 at resected DNA DSBs IEA Sus scrofa A0A287AQ29 R-SSC-5685011 https://reactome.org/PathwayBrowser/#/R-SSC-5685011 ATR activation at DNA DSBs IEA Sus scrofa A0A287AQ29 R-SSC-5685156 https://reactome.org/PathwayBrowser/#/R-SSC-5685156 ATR phosphorylates RPA2 IEA Sus scrofa A0A287AQ29 R-SSC-5685341 https://reactome.org/PathwayBrowser/#/R-SSC-5685341 BCDX2 complex stabilizes RAD51 filament IEA Sus scrofa A0A287AQ29 R-SSC-5685838 https://reactome.org/PathwayBrowser/#/R-SSC-5685838 CX3 complex binds D-loop structures IEA Sus scrofa A0A287AQ29 R-SSC-5685985 https://reactome.org/PathwayBrowser/#/R-SSC-5685985 EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment IEA Sus scrofa A0A287AQ29 R-SSC-5685994 https://reactome.org/PathwayBrowser/#/R-SSC-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Sus scrofa A0A287AQ29 R-SSC-5686440 https://reactome.org/PathwayBrowser/#/R-SSC-5686440 MUS81:EME1,EME2 cleaves D-loop IEA Sus scrofa A0A287AQ29 R-SSC-5686642 https://reactome.org/PathwayBrowser/#/R-SSC-5686642 RAD52 promotes single strand annealing at resected DNA DSBs IEA Sus scrofa A0A287AQ29 R-SSC-5686657 https://reactome.org/PathwayBrowser/#/R-SSC-5686657 ERCC1:XPF cleaves flaps generated by SSA IEA Sus scrofa A0A287AQ29 R-SSC-5693539 https://reactome.org/PathwayBrowser/#/R-SSC-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Sus scrofa A0A287AQ29 R-SSC-5693542 https://reactome.org/PathwayBrowser/#/R-SSC-5693542 Association of RPA complexes with ssDNA at resected DNA DSBs IEA Sus scrofa A0A287AQ29 R-SSC-5693564 https://reactome.org/PathwayBrowser/#/R-SSC-5693564 Association of RAD51 with RAD52:DNA double-strand break ends IEA Sus scrofa A0A287AQ29 R-SSC-5693580 https://reactome.org/PathwayBrowser/#/R-SSC-5693580 Association of RAD52 with the RPA complex at resected DNA DSBs IEA Sus scrofa A0A287AQ29 R-SSC-5693584 https://reactome.org/PathwayBrowser/#/R-SSC-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Sus scrofa A0A287AQ29 R-SSC-5693593 https://reactome.org/PathwayBrowser/#/R-SSC-5693593 D-loop extension by DNA polymerases IEA Sus scrofa A0A287AQ29 R-SSC-5693620 https://reactome.org/PathwayBrowser/#/R-SSC-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Sus scrofa A0A287AQ29 R-SSC-6799332 https://reactome.org/PathwayBrowser/#/R-SSC-6799332 ATR phosphorylates TP53 IEA Sus scrofa A0A287AQ29 R-SSC-9853389 https://reactome.org/PathwayBrowser/#/R-SSC-9853389 FIGNL1 binds RAD51 IEA Sus scrofa A0A287AQ31 R-SSC-109639 https://reactome.org/PathwayBrowser/#/R-SSC-109639 Formation of the closed pre-initiation complex IEA Sus scrofa A0A287AQ31 R-SSC-111264 https://reactome.org/PathwayBrowser/#/R-SSC-111264 Addition of nucleotides between position +11 and +30 IEA Sus scrofa A0A287AQ31 R-SSC-112379 https://reactome.org/PathwayBrowser/#/R-SSC-112379 Recruitment of elongation factors to form elongation complex IEA Sus scrofa A0A287AQ31 R-SSC-112383 https://reactome.org/PathwayBrowser/#/R-SSC-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein IEA Sus scrofa A0A287AQ31 R-SSC-112385 https://reactome.org/PathwayBrowser/#/R-SSC-112385 Addition of nucleotides leads to transcript elongation IEA Sus scrofa A0A287AQ31 R-SSC-113430 https://reactome.org/PathwayBrowser/#/R-SSC-113430 Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex IEA Sus scrofa A0A287AQ31 R-SSC-5689317 https://reactome.org/PathwayBrowser/#/R-SSC-5689317 Formation of the pre-incision complex in GG-NER IEA Sus scrofa A0A287AQ31 R-SSC-5689861 https://reactome.org/PathwayBrowser/#/R-SSC-5689861 Recruitment of XPA and release of CAK IEA Sus scrofa A0A287AQ31 R-SSC-5690213 https://reactome.org/PathwayBrowser/#/R-SSC-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Sus scrofa A0A287AQ31 R-SSC-5690988 https://reactome.org/PathwayBrowser/#/R-SSC-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Sus scrofa A0A287AQ31 R-SSC-5690990 https://reactome.org/PathwayBrowser/#/R-SSC-5690990 5'- incision of DNA by ERCC1:ERCC4 in GG-NER IEA Sus scrofa A0A287AQ31 R-SSC-5690991 https://reactome.org/PathwayBrowser/#/R-SSC-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER IEA Sus scrofa A0A287AQ31 R-SSC-5690996 https://reactome.org/PathwayBrowser/#/R-SSC-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Sus scrofa A0A287AQ31 R-SSC-5691000 https://reactome.org/PathwayBrowser/#/R-SSC-5691000 TFIIH binds GG-NER site to form a verification complex IEA Sus scrofa A0A287AQ31 R-SSC-5696670 https://reactome.org/PathwayBrowser/#/R-SSC-5696670 CHD1L is recruited to GG-NER site IEA Sus scrofa A0A287AQ31 R-SSC-6781818 https://reactome.org/PathwayBrowser/#/R-SSC-6781818 RNA Pol II initiates transcription from damaged DNA template IEA Sus scrofa A0A287AQ31 R-SSC-6781824 https://reactome.org/PathwayBrowser/#/R-SSC-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template IEA Sus scrofa A0A287AQ31 R-SSC-6781833 https://reactome.org/PathwayBrowser/#/R-SSC-6781833 ERCC8 (CSA) binds stalled RNA Pol II IEA Sus scrofa A0A287AQ31 R-SSC-6781867 https://reactome.org/PathwayBrowser/#/R-SSC-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Sus scrofa A0A287AQ31 R-SSC-6782004 https://reactome.org/PathwayBrowser/#/R-SSC-6782004 Assembly of the pre-incision complex in TC-NER IEA Sus scrofa A0A287AQ31 R-SSC-6782069 https://reactome.org/PathwayBrowser/#/R-SSC-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Sus scrofa A0A287AQ31 R-SSC-6782131 https://reactome.org/PathwayBrowser/#/R-SSC-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa A0A287AQ31 R-SSC-6782138 https://reactome.org/PathwayBrowser/#/R-SSC-6782138 ERCC5 and RPA bind TC-NER site IEA Sus scrofa A0A287AQ31 R-SSC-6782141 https://reactome.org/PathwayBrowser/#/R-SSC-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Sus scrofa A0A287AQ31 R-SSC-6782204 https://reactome.org/PathwayBrowser/#/R-SSC-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Sus scrofa A0A287AQ31 R-SSC-6782208 https://reactome.org/PathwayBrowser/#/R-SSC-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Sus scrofa A0A287AQ31 R-SSC-6782211 https://reactome.org/PathwayBrowser/#/R-SSC-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Sus scrofa A0A287AQ31 R-SSC-6782224 https://reactome.org/PathwayBrowser/#/R-SSC-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Sus scrofa A0A287AQ31 R-SSC-6782227 https://reactome.org/PathwayBrowser/#/R-SSC-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Sus scrofa A0A287AQ31 R-SSC-6790454 https://reactome.org/PathwayBrowser/#/R-SSC-6790454 SUMOylation of XPC IEA Sus scrofa A0A287AQ31 R-SSC-6797606 https://reactome.org/PathwayBrowser/#/R-SSC-6797606 CDK12 phosphorylates RNA Pol II CTD at DNA repair genes IEA Sus scrofa A0A287AQ31 R-SSC-6797616 https://reactome.org/PathwayBrowser/#/R-SSC-6797616 CCNK:CDK12 binds RNA Pol II at DNA repair genes IEA Sus scrofa A0A287AQ31 R-SSC-73758 https://reactome.org/PathwayBrowser/#/R-SSC-73758 Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter IEA Sus scrofa A0A287AQ31 R-SSC-73769 https://reactome.org/PathwayBrowser/#/R-SSC-73769 Loss of Rrn3 from RNA Polymerase I promoter escape complex IEA Sus scrofa A0A287AQ31 R-SSC-73946 https://reactome.org/PathwayBrowser/#/R-SSC-73946 Abortive initiation after formation of the first phosphodiester bond IEA Sus scrofa A0A287AQ31 R-SSC-74986 https://reactome.org/PathwayBrowser/#/R-SSC-74986 Elongation of pre-rRNA transcript IEA Sus scrofa A0A287AQ31 R-SSC-74993 https://reactome.org/PathwayBrowser/#/R-SSC-74993 PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box IEA Sus scrofa A0A287AQ31 R-SSC-75850 https://reactome.org/PathwayBrowser/#/R-SSC-75850 Addition of the third nucleotide on the nascent transcript IEA Sus scrofa A0A287AQ31 R-SSC-75856 https://reactome.org/PathwayBrowser/#/R-SSC-75856 Abortive Initiation Before Second Transition IEA Sus scrofa A0A287AQ31 R-SSC-75861 https://reactome.org/PathwayBrowser/#/R-SSC-75861 NTP Binds Active Site of RNA Polymerase II IEA Sus scrofa A0A287AQ31 R-SSC-75862 https://reactome.org/PathwayBrowser/#/R-SSC-75862 Fall Back to Closed Pre-initiation Complex IEA Sus scrofa A0A287AQ31 R-SSC-75864 https://reactome.org/PathwayBrowser/#/R-SSC-75864 Newly Formed Phosphodiester Bond Stabilized and PPi Released IEA Sus scrofa A0A287AQ31 R-SSC-75866 https://reactome.org/PathwayBrowser/#/R-SSC-75866 Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP IEA Sus scrofa A0A287AQ31 R-SSC-75869 https://reactome.org/PathwayBrowser/#/R-SSC-75869 Addition of the fourth nucleotide on the Nascent Transcript: Second Transition IEA Sus scrofa A0A287AQ31 R-SSC-75873 https://reactome.org/PathwayBrowser/#/R-SSC-75873 Addition of Nucleotides 5 through 9 on the growing Transcript IEA Sus scrofa A0A287AQ31 R-SSC-75891 https://reactome.org/PathwayBrowser/#/R-SSC-75891 Abortive Initiation After Second Transition IEA Sus scrofa A0A287AQ31 R-SSC-75949 https://reactome.org/PathwayBrowser/#/R-SSC-75949 RNA Polymerase II Promoter Opening: First Transition IEA Sus scrofa A0A287AQ31 R-SSC-76576 https://reactome.org/PathwayBrowser/#/R-SSC-76576 Addition of nucleotides 10 and 11 on the growing transcript: Third Transition IEA Sus scrofa A0A287AQ31 R-SSC-77068 https://reactome.org/PathwayBrowser/#/R-SSC-77068 Activation of GT IEA Sus scrofa A0A287AQ31 R-SSC-77069 https://reactome.org/PathwayBrowser/#/R-SSC-77069 RNA Polymerase II CTD (phosphorylated) binds to CE IEA Sus scrofa A0A287AQ31 R-SSC-77071 https://reactome.org/PathwayBrowser/#/R-SSC-77071 Phosphorylation (Ser5) of RNA pol II CTD IEA Sus scrofa A0A287AQ31 R-SSC-77073 https://reactome.org/PathwayBrowser/#/R-SSC-77073 SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) IEA Sus scrofa A0A287AQ31 R-SSC-77077 https://reactome.org/PathwayBrowser/#/R-SSC-77077 Capping complex formation IEA Sus scrofa A0A287AQ31 R-SSC-77078 https://reactome.org/PathwayBrowser/#/R-SSC-77078 Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme IEA Sus scrofa A0A287AQ31 R-SSC-77081 https://reactome.org/PathwayBrowser/#/R-SSC-77081 Formation of the CE:GMP intermediate complex IEA Sus scrofa A0A287AQ31 R-SSC-77083 https://reactome.org/PathwayBrowser/#/R-SSC-77083 Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA IEA Sus scrofa A0A287AQ31 R-SSC-77085 https://reactome.org/PathwayBrowser/#/R-SSC-77085 Dissociation of transcript with 5'-GMP from GT IEA Sus scrofa A0A287AQ31 R-SSC-77090 https://reactome.org/PathwayBrowser/#/R-SSC-77090 Methylation of GMP-cap by RNA Methyltransferase IEA Sus scrofa A0A287AQ31 R-SSC-9613494 https://reactome.org/PathwayBrowser/#/R-SSC-9613494 Unwinding of DNA for the Nascent Transcript: Second Transition IEA Sus scrofa A0A287AQ31 R-SSC-9613497 https://reactome.org/PathwayBrowser/#/R-SSC-9613497 Unwinding DNA for the nascent transcript IEA Sus scrofa A0A287AQ31 R-SSC-9684118 https://reactome.org/PathwayBrowser/#/R-SSC-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa A0A287AQ32 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287AQ37 R-SSC-8937369 https://reactome.org/PathwayBrowser/#/R-SSC-8937369 ATAD2 binds ESR1 IEA Sus scrofa A0A287AQ38 R-SSC-1602466 https://reactome.org/PathwayBrowser/#/R-SSC-1602466 Activation of MT-MMPs by FURIN IEA Sus scrofa A0A287AQ38 R-SSC-1605825 https://reactome.org/PathwayBrowser/#/R-SSC-1605825 MT-MMPs are sorted to the plasma membrane IEA Sus scrofa A0A287AQ41 R-SSC-5226999 https://reactome.org/PathwayBrowser/#/R-SSC-5226999 ADD1:ADD3 binds DMTN IEA Sus scrofa A0A287AQ41 R-SSC-9693125 https://reactome.org/PathwayBrowser/#/R-SSC-9693125 RHOF binds effectors at the plasma membrane IEA Sus scrofa A0A287AQ41 R-SSC-9693198 https://reactome.org/PathwayBrowser/#/R-SSC-9693198 RHOD binds effectors at the plasma membrane IEA Sus scrofa A0A287AQ67 R-SSC-156808 https://reactome.org/PathwayBrowser/#/R-SSC-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Sus scrofa A0A287AQ67 R-SSC-156823 https://reactome.org/PathwayBrowser/#/R-SSC-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Sus scrofa A0A287AQ67 R-SSC-157849 https://reactome.org/PathwayBrowser/#/R-SSC-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Sus scrofa A0A287AQ67 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A287AQ67 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa A0A287AQ67 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A287AQ67 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A287AQ67 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A287AQ67 R-SSC-72676 https://reactome.org/PathwayBrowser/#/R-SSC-72676 eIF3 and eIF1A bind to the 40S subunit IEA Sus scrofa A0A287AQ67 R-SSC-72691 https://reactome.org/PathwayBrowser/#/R-SSC-72691 Formation of the 43S pre-initiation complex IEA Sus scrofa A0A287AQ67 R-SSC-72697 https://reactome.org/PathwayBrowser/#/R-SSC-72697 Start codon recognition IEA Sus scrofa A0A287AQ67 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A287AQ67 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A287AQ67 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A287AQ67 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A287AQ67 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A287AQ81 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa A0A287AQ81 R-SSC-420214 https://reactome.org/PathwayBrowser/#/R-SSC-420214 The adrenomedullin receptor can bind adrenomedullin and intermedin IEA Sus scrofa A0A287AQ81 R-SSC-9733292 https://reactome.org/PathwayBrowser/#/R-SSC-9733292 AMY1-3 bind pramlintide IEA Sus scrofa A0A287AQA5 R-SSC-2022052 https://reactome.org/PathwayBrowser/#/R-SSC-2022052 Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS) IEA Sus scrofa A0A287AQA7 R-SSC-9013110 https://reactome.org/PathwayBrowser/#/R-SSC-9013110 RHOC binds effectors at the plasma membrane IEA Sus scrofa A0A287AQB4 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AQC9 R-SSC-6791218 https://reactome.org/PathwayBrowser/#/R-SSC-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Sus scrofa A0A287AQC9 R-SSC-6791219 https://reactome.org/PathwayBrowser/#/R-SSC-6791219 32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA IEA Sus scrofa A0A287AQD3 R-SSC-2130349 https://reactome.org/PathwayBrowser/#/R-SSC-2130349 Generation of CLIP from lip10 IEA Sus scrofa A0A287AQD3 R-SSC-2130504 https://reactome.org/PathwayBrowser/#/R-SSC-2130504 Cleavage of lip22 to lip10 IEA Sus scrofa A0A287AQD3 R-SSC-2130706 https://reactome.org/PathwayBrowser/#/R-SSC-2130706 MHC class II antigen processing IEA Sus scrofa A0A287AQF5 R-SSC-426240 https://reactome.org/PathwayBrowser/#/R-SSC-426240 DAG kinase produces phosphatidic acid from DAG IEA Sus scrofa A0A287AQH0 R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa A0A287AQH0 R-SSC-6805650 https://reactome.org/PathwayBrowser/#/R-SSC-6805650 MTA2-NuRD complex deacetylates TP53 IEA Sus scrofa A0A287AQH0 R-SSC-73739 https://reactome.org/PathwayBrowser/#/R-SSC-73739 Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter IEA Sus scrofa A0A287AQH0 R-SSC-8943780 https://reactome.org/PathwayBrowser/#/R-SSC-8943780 SALL4 recruits NuRD to PTEN gene IEA Sus scrofa A0A287AQH0 R-SSC-9679787 https://reactome.org/PathwayBrowser/#/R-SSC-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Sus scrofa A0A287AQJ4 R-SSC-140978 https://reactome.org/PathwayBrowser/#/R-SSC-140978 TRADD:TRAF2:RIP1 binds FADD IEA Sus scrofa A0A287AQJ4 R-SSC-5357776 https://reactome.org/PathwayBrowser/#/R-SSC-5357776 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG IEA Sus scrofa A0A287AQJ4 R-SSC-5357845 https://reactome.org/PathwayBrowser/#/R-SSC-5357845 K63polyUb-RIPK1 is deubiquitinated IEA Sus scrofa A0A287AQJ4 R-SSC-5357860 https://reactome.org/PathwayBrowser/#/R-SSC-5357860 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex IEA Sus scrofa A0A287AQJ4 R-SSC-8869456 https://reactome.org/PathwayBrowser/#/R-SSC-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Sus scrofa A0A287AQK8 R-SSC-9865449 https://reactome.org/PathwayBrowser/#/R-SSC-9865449 Metallochaperone inserts Cu2+ into MT-CO1 IEA Sus scrofa A0A287AQK8 R-SSC-9865579 https://reactome.org/PathwayBrowser/#/R-SSC-9865579 MT-CO1 and MT-CO2 complexes associate, installing heme moieties IEA Sus scrofa A0A287AQK8 R-SSC-9865630 https://reactome.org/PathwayBrowser/#/R-SSC-9865630 Metallochaperone inserts 2Cu2+ into MT-CO2 IEA Sus scrofa A0A287AQL1 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa A0A287AQP0 R-SSC-109700 https://reactome.org/PathwayBrowser/#/R-SSC-109700 AKT2 binds PIP3 IEA Sus scrofa A0A287AQP0 R-SSC-109702 https://reactome.org/PathwayBrowser/#/R-SSC-109702 PDPK1 phosphorylates AKT2 IEA Sus scrofa A0A287AQP0 R-SSC-165162 https://reactome.org/PathwayBrowser/#/R-SSC-165162 Phosphorylation of TSC2 by PKB IEA Sus scrofa A0A287AQP0 R-SSC-165182 https://reactome.org/PathwayBrowser/#/R-SSC-165182 Phosphorylation of complexed TSC2 by PKB IEA Sus scrofa A0A287AQS7 R-SSC-9865449 https://reactome.org/PathwayBrowser/#/R-SSC-9865449 Metallochaperone inserts Cu2+ into MT-CO1 IEA Sus scrofa A0A287AQS7 R-SSC-9865579 https://reactome.org/PathwayBrowser/#/R-SSC-9865579 MT-CO1 and MT-CO2 complexes associate, installing heme moieties IEA Sus scrofa A0A287AQS7 R-SSC-9865630 https://reactome.org/PathwayBrowser/#/R-SSC-9865630 Metallochaperone inserts 2Cu2+ into MT-CO2 IEA Sus scrofa A0A287AQT2 R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Sus scrofa A0A287AQT2 R-SSC-6799179 https://reactome.org/PathwayBrowser/#/R-SSC-6799179 Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex IEA Sus scrofa A0A287AQT2 R-SSC-6799196 https://reactome.org/PathwayBrowser/#/R-SSC-6799196 The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I IEA Sus scrofa A0A287AQT2 R-SSC-6799199 https://reactome.org/PathwayBrowser/#/R-SSC-6799199 COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex IEA Sus scrofa A0A287AQT2 R-SSC-6799202 https://reactome.org/PathwayBrowser/#/R-SSC-6799202 The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex IEA Sus scrofa A0A287AQT5 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A287AQT5 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A287AQT5 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A287AQT5 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A287AQT5 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A287AQV3 R-SSC-2029471 https://reactome.org/PathwayBrowser/#/R-SSC-2029471 Hydrolysis of PC to PA by PLD IEA Sus scrofa A0A287AQV4 R-SSC-1614524 https://reactome.org/PathwayBrowser/#/R-SSC-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Sus scrofa A0A287AQV5 R-SSC-2671885 https://reactome.org/PathwayBrowser/#/R-SSC-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Sus scrofa A0A287AQV5 R-SSC-8863494 https://reactome.org/PathwayBrowser/#/R-SSC-8863494 ASICs bind STOML3, (STOM) IEA Sus scrofa A0A287AQV5 R-SSC-9650165 https://reactome.org/PathwayBrowser/#/R-SSC-9650165 ASIC trimers bind H+ IEA Sus scrofa A0A287AQW1 R-SSC-622326 https://reactome.org/PathwayBrowser/#/R-SSC-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Sus scrofa A0A287AQW1 R-SSC-629595 https://reactome.org/PathwayBrowser/#/R-SSC-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Sus scrofa A0A287AQW1 R-SSC-629596 https://reactome.org/PathwayBrowser/#/R-SSC-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Sus scrofa A0A287AQW1 R-SSC-629599 https://reactome.org/PathwayBrowser/#/R-SSC-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Sus scrofa A0A287AQX2 R-SSC-201035 https://reactome.org/PathwayBrowser/#/R-SSC-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Sus scrofa A0A287AQX9 R-SSC-2064406 https://reactome.org/PathwayBrowser/#/R-SSC-2064406 Translocation of YAP1:ZO-2 (TJP2) to the nucleus IEA Sus scrofa A0A287AQX9 R-SSC-2064418 https://reactome.org/PathwayBrowser/#/R-SSC-2064418 WWTR1 (TAZ) binds ZO-2 (TJP2) IEA Sus scrofa A0A287AQX9 R-SSC-2064421 https://reactome.org/PathwayBrowser/#/R-SSC-2064421 YAP1 binds ZO-2 (TJP2) IEA Sus scrofa A0A287AQX9 R-SSC-351871 https://reactome.org/PathwayBrowser/#/R-SSC-351871 Caspase-mediated cleavage of Z0-2 IEA Sus scrofa A0A287AQX9 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa A0A287AQX9 R-SSC-9013024 https://reactome.org/PathwayBrowser/#/R-SSC-9013024 RHOB binds effectors at the plasma membrane IEA Sus scrofa A0A287AQX9 R-SSC-9013110 https://reactome.org/PathwayBrowser/#/R-SSC-9013110 RHOC binds effectors at the plasma membrane IEA Sus scrofa A0A287AR23 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A287AR23 R-SSC-9014294 https://reactome.org/PathwayBrowser/#/R-SSC-9014294 RAC2 binds effectors at the plasma membrane IEA Sus scrofa A0A287AR23 R-SSC-9014449 https://reactome.org/PathwayBrowser/#/R-SSC-9014449 RHOG binds effectors at the plasma membrane IEA Sus scrofa A0A287AR23 R-SSC-9018746 https://reactome.org/PathwayBrowser/#/R-SSC-9018746 RHOQ binds effectors at the plasma membrane IEA Sus scrofa A0A287AR23 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa A0A287AR30 R-SSC-2395818 https://reactome.org/PathwayBrowser/#/R-SSC-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Sus scrofa A0A287AR30 R-SSC-2395849 https://reactome.org/PathwayBrowser/#/R-SSC-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Sus scrofa A0A287AR30 R-SSC-2395872 https://reactome.org/PathwayBrowser/#/R-SSC-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Sus scrofa A0A287AR30 R-SSC-9731228 https://reactome.org/PathwayBrowser/#/R-SSC-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Sus scrofa A0A287AR30 R-SSC-9731590 https://reactome.org/PathwayBrowser/#/R-SSC-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Sus scrofa A0A287AR30 R-SSC-9731613 https://reactome.org/PathwayBrowser/#/R-SSC-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Sus scrofa A0A287AR30 R-SSC-9731632 https://reactome.org/PathwayBrowser/#/R-SSC-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Sus scrofa A0A287AR46 R-SSC-482772 https://reactome.org/PathwayBrowser/#/R-SSC-482772 Release of platelet cytosolic components IEA Sus scrofa A0A287AR48 R-SSC-70997 https://reactome.org/PathwayBrowser/#/R-SSC-70997 SUCLG1/A2 cleaves succinyl-CoA IEA Sus scrofa A0A287AR57 R-SSC-5683964 https://reactome.org/PathwayBrowser/#/R-SSC-5683964 ATM phosphorylates EYA1-4 IEA Sus scrofa A0A287AR57 R-SSC-5683967 https://reactome.org/PathwayBrowser/#/R-SSC-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Sus scrofa A0A287AR63 R-SSC-159101 https://reactome.org/PathwayBrowser/#/R-SSC-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Sus scrofa A0A287AR63 R-SSC-72180 https://reactome.org/PathwayBrowser/#/R-SSC-72180 Cleavage of mRNA at the 3'-end IEA Sus scrofa A0A287AR63 R-SSC-72185 https://reactome.org/PathwayBrowser/#/R-SSC-72185 mRNA polyadenylation IEA Sus scrofa A0A287AR63 R-SSC-8849157 https://reactome.org/PathwayBrowser/#/R-SSC-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Sus scrofa A0A287AR65 R-SSC-8867047 https://reactome.org/PathwayBrowser/#/R-SSC-8867047 PTPN3 dephosphorylates EPS15 IEA Sus scrofa A0A287AR65 R-SSC-8867654 https://reactome.org/PathwayBrowser/#/R-SSC-8867654 PTPN3 binds p-T183,Y185 MAPK12 IEA Sus scrofa A0A287AR65 R-SSC-8867658 https://reactome.org/PathwayBrowser/#/R-SSC-8867658 PTPN3 dephosphorylates MAPK12 IEA Sus scrofa A0A287AR65 R-SSC-8868118 https://reactome.org/PathwayBrowser/#/R-SSC-8868118 MAPK12 phosphorylates PTPN3 IEA Sus scrofa A0A287AR75 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A287AR75 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa A0A287AR75 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa A0A287AR75 R-SSC-983259 https://reactome.org/PathwayBrowser/#/R-SSC-983259 Kinesins move along microtubules consuming ATP IEA Sus scrofa A0A287AR75 R-SSC-983266 https://reactome.org/PathwayBrowser/#/R-SSC-983266 Kinesins bind microtubules IEA Sus scrofa A0A287ARA1 R-SSC-5624949 https://reactome.org/PathwayBrowser/#/R-SSC-5624949 Assembly of the anterograde IFT train IEA Sus scrofa A0A287ARA1 R-SSC-5624952 https://reactome.org/PathwayBrowser/#/R-SSC-5624952 Assembly of the retrograde IFT train IEA Sus scrofa A0A287ARA1 R-SSC-5625416 https://reactome.org/PathwayBrowser/#/R-SSC-5625416 Anterograde IFT IEA Sus scrofa A0A287ARA1 R-SSC-5625421 https://reactome.org/PathwayBrowser/#/R-SSC-5625421 The anterograde IFT train dissociates IEA Sus scrofa A0A287ARA1 R-SSC-5625424 https://reactome.org/PathwayBrowser/#/R-SSC-5625424 The retrograde IFT train dissociates IEA Sus scrofa A0A287ARA1 R-SSC-5625426 https://reactome.org/PathwayBrowser/#/R-SSC-5625426 Retrograde IFT IEA Sus scrofa A0A287ARB7 R-SSC-4084978 https://reactome.org/PathwayBrowser/#/R-SSC-4084978 ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues IEA Sus scrofa A0A287ARC4 R-SSC-9717830 https://reactome.org/PathwayBrowser/#/R-SSC-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Sus scrofa A0A287ARC4 R-SSC-9717834 https://reactome.org/PathwayBrowser/#/R-SSC-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Sus scrofa A0A287ARC6 R-SSC-5688786 https://reactome.org/PathwayBrowser/#/R-SSC-5688786 ATXN3 binds RAD23 IEA Sus scrofa A0A287ARC6 R-SSC-5689861 https://reactome.org/PathwayBrowser/#/R-SSC-5689861 Recruitment of XPA and release of CAK IEA Sus scrofa A0A287ARC6 R-SSC-5690996 https://reactome.org/PathwayBrowser/#/R-SSC-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Sus scrofa A0A287ARC6 R-SSC-5691000 https://reactome.org/PathwayBrowser/#/R-SSC-5691000 TFIIH binds GG-NER site to form a verification complex IEA Sus scrofa A0A287ARC6 R-SSC-5696655 https://reactome.org/PathwayBrowser/#/R-SSC-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Sus scrofa A0A287ARC6 R-SSC-5696664 https://reactome.org/PathwayBrowser/#/R-SSC-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Sus scrofa A0A287ARC6 R-SSC-5696670 https://reactome.org/PathwayBrowser/#/R-SSC-5696670 CHD1L is recruited to GG-NER site IEA Sus scrofa A0A287ARC6 R-SSC-6782943 https://reactome.org/PathwayBrowser/#/R-SSC-6782943 UV-DDB ubiquitinates XPC IEA Sus scrofa A0A287ARC6 R-SSC-6790454 https://reactome.org/PathwayBrowser/#/R-SSC-6790454 SUMOylation of XPC IEA Sus scrofa A0A287ARE8 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A287ARE8 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A287ARE8 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A287ARE8 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A287ARE8 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287ARE8 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287ARE8 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287ARE8 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287ARE8 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287ARE8 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287ARE8 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A287ARE8 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A287ARE8 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A287ARE8 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A287ARE8 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287ARG4 R-SSC-6805546 https://reactome.org/PathwayBrowser/#/R-SSC-6805546 Keratin type I binds keratin type II IEA Sus scrofa A0A287ARG4 R-SSC-6805573 https://reactome.org/PathwayBrowser/#/R-SSC-6805573 Keratin type I/type II heterodimers form tetramers IEA Sus scrofa A0A287ARG4 R-SSC-6806610 https://reactome.org/PathwayBrowser/#/R-SSC-6806610 Keratin filament formation IEA Sus scrofa A0A287ARG4 R-SSC-6806613 https://reactome.org/PathwayBrowser/#/R-SSC-6806613 Keratin tetramers bind to form unit length filaments IEA Sus scrofa A0A287ARG4 R-SSC-6806629 https://reactome.org/PathwayBrowser/#/R-SSC-6806629 Formation of tonofilament bundles IEA Sus scrofa A0A287ARG4 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A287ARG4 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287ARG4 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A287ARG4 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A287ARH1 R-SSC-3321805 https://reactome.org/PathwayBrowser/#/R-SSC-3321805 NSL acetylates histone H4 IEA Sus scrofa A0A287ARI1 R-SSC-156808 https://reactome.org/PathwayBrowser/#/R-SSC-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Sus scrofa A0A287ARI1 R-SSC-156823 https://reactome.org/PathwayBrowser/#/R-SSC-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Sus scrofa A0A287ARI1 R-SSC-157849 https://reactome.org/PathwayBrowser/#/R-SSC-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Sus scrofa A0A287ARI1 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa A0A287ARI1 R-SSC-72676 https://reactome.org/PathwayBrowser/#/R-SSC-72676 eIF3 and eIF1A bind to the 40S subunit IEA Sus scrofa A0A287ARI1 R-SSC-72691 https://reactome.org/PathwayBrowser/#/R-SSC-72691 Formation of the 43S pre-initiation complex IEA Sus scrofa A0A287ARI1 R-SSC-72697 https://reactome.org/PathwayBrowser/#/R-SSC-72697 Start codon recognition IEA Sus scrofa A0A287ARJ1 R-SSC-72095 https://reactome.org/PathwayBrowser/#/R-SSC-72095 Internal Methylation of mRNA IEA Sus scrofa A0A287ARK0 R-SSC-6805546 https://reactome.org/PathwayBrowser/#/R-SSC-6805546 Keratin type I binds keratin type II IEA Sus scrofa A0A287ARK0 R-SSC-6805573 https://reactome.org/PathwayBrowser/#/R-SSC-6805573 Keratin type I/type II heterodimers form tetramers IEA Sus scrofa A0A287ARK0 R-SSC-6806610 https://reactome.org/PathwayBrowser/#/R-SSC-6806610 Keratin filament formation IEA Sus scrofa A0A287ARK0 R-SSC-6806613 https://reactome.org/PathwayBrowser/#/R-SSC-6806613 Keratin tetramers bind to form unit length filaments IEA Sus scrofa A0A287ARK0 R-SSC-6806629 https://reactome.org/PathwayBrowser/#/R-SSC-6806629 Formation of tonofilament bundles IEA Sus scrofa A0A287ARK0 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A287ARK0 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287ARK0 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A287ARK0 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A287ARK3 R-SSC-5689544 https://reactome.org/PathwayBrowser/#/R-SSC-5689544 UCHL5 binds INO80 complex IEA Sus scrofa A0A287ARK8 R-SSC-5685607 https://reactome.org/PathwayBrowser/#/R-SSC-5685607 Sialic acid binds SIGLEC IEA Sus scrofa A0A287ARK8 R-SSC-5690669 https://reactome.org/PathwayBrowser/#/R-SSC-5690669 CD22 binds itself to form homo-oligomers IEA Sus scrofa A0A287ARK8 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287ARK8 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287ARK8 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287ARK8 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287ARL6 R-SSC-419001 https://reactome.org/PathwayBrowser/#/R-SSC-419001 Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin IEA Sus scrofa A0A287ARL6 R-SSC-419002 https://reactome.org/PathwayBrowser/#/R-SSC-419002 Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin IEA Sus scrofa A0A287ARM7 R-SSC-444126 https://reactome.org/PathwayBrowser/#/R-SSC-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Sus scrofa A0A287ARM8 R-SSC-6814684 https://reactome.org/PathwayBrowser/#/R-SSC-6814684 cis-SNARE binds SNAPs and NSF hexamer at the TGN IEA Sus scrofa A0A287ARM8 R-SSC-8866277 https://reactome.org/PathwayBrowser/#/R-SSC-8866277 AP-2 directly binds some endocytic cargo IEA Sus scrofa A0A287ARM8 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A287ARM8 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A287ARM8 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A287ARM8 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A287ARM8 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A287ARM8 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287ARM8 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287ARM8 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287ARM8 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287ARM8 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287ARM8 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287ARM8 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287ARM8 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287ARM8 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287ARN0 R-SSC-1296043 https://reactome.org/PathwayBrowser/#/R-SSC-1296043 Activation of HCN channels IEA Sus scrofa A0A287ARN0 R-SSC-1297444 https://reactome.org/PathwayBrowser/#/R-SSC-1297444 Binding of cAMP to HCN channels IEA Sus scrofa A0A287ARN0 R-SSC-9726875 https://reactome.org/PathwayBrowser/#/R-SSC-9726875 HCNs:cAMP bind SNIs IEA Sus scrofa A0A287ARN1 R-SSC-8983059 https://reactome.org/PathwayBrowser/#/R-SSC-8983059 STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex IEA Sus scrofa A0A287ARN4 R-SSC-5633051 https://reactome.org/PathwayBrowser/#/R-SSC-5633051 EFCAB7:IQCE binds EVC2:EVC IEA Sus scrofa A0A287ART1 R-SSC-8981637 https://reactome.org/PathwayBrowser/#/R-SSC-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Sus scrofa A0A287ART1 R-SSC-9013144 https://reactome.org/PathwayBrowser/#/R-SSC-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Sus scrofa A0A287ART1 R-SSC-9013161 https://reactome.org/PathwayBrowser/#/R-SSC-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Sus scrofa A0A287ART1 R-SSC-9018766 https://reactome.org/PathwayBrowser/#/R-SSC-9018766 RHOU binds effectors at the plasma membrane IEA Sus scrofa A0A287ART4 R-SSC-6805546 https://reactome.org/PathwayBrowser/#/R-SSC-6805546 Keratin type I binds keratin type II IEA Sus scrofa A0A287ART4 R-SSC-6805573 https://reactome.org/PathwayBrowser/#/R-SSC-6805573 Keratin type I/type II heterodimers form tetramers IEA Sus scrofa A0A287ART4 R-SSC-6806610 https://reactome.org/PathwayBrowser/#/R-SSC-6806610 Keratin filament formation IEA Sus scrofa A0A287ART4 R-SSC-6806613 https://reactome.org/PathwayBrowser/#/R-SSC-6806613 Keratin tetramers bind to form unit length filaments IEA Sus scrofa A0A287ART4 R-SSC-6806629 https://reactome.org/PathwayBrowser/#/R-SSC-6806629 Formation of tonofilament bundles IEA Sus scrofa A0A287ART4 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A287ART4 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287ART4 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A287ART4 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A287ART8 R-SSC-5654985 https://reactome.org/PathwayBrowser/#/R-SSC-5654985 SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH IEA Sus scrofa A0A287ART8 R-SSC-5654986 https://reactome.org/PathwayBrowser/#/R-SSC-5654986 SPRTN binds monoUb:K164-PCNA associated with POLH IEA Sus scrofa A0A287ART8 R-SSC-5654989 https://reactome.org/PathwayBrowser/#/R-SSC-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Sus scrofa A0A287ARU4 R-SSC-1170539 https://reactome.org/PathwayBrowser/#/R-SSC-1170539 Prolactin receptor is internalized IEA Sus scrofa A0A287ARU4 R-SSC-1363328 https://reactome.org/PathwayBrowser/#/R-SSC-1363328 Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex IEA Sus scrofa A0A287ARU4 R-SSC-1363331 https://reactome.org/PathwayBrowser/#/R-SSC-1363331 Ubiquitination of p130 (RBL2) by SCF (Skp2) IEA Sus scrofa A0A287ARU4 R-SSC-1370500 https://reactome.org/PathwayBrowser/#/R-SSC-1370500 PRLR binds SCF beta-TrCP complex IEA Sus scrofa A0A287ARU4 R-SSC-174159 https://reactome.org/PathwayBrowser/#/R-SSC-174159 Ubiquitination of Emi1 by SCF-beta-TrCP IEA Sus scrofa A0A287ARU4 R-SSC-187545 https://reactome.org/PathwayBrowser/#/R-SSC-187545 Association of Cks1 with SCF(Skp2) complex IEA Sus scrofa A0A287ARU4 R-SSC-187552 https://reactome.org/PathwayBrowser/#/R-SSC-187552 Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex IEA Sus scrofa A0A287ARU4 R-SSC-187574 https://reactome.org/PathwayBrowser/#/R-SSC-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Sus scrofa A0A287ARU4 R-SSC-187575 https://reactome.org/PathwayBrowser/#/R-SSC-187575 Ubiquitination of phospho-p27/p21 IEA Sus scrofa A0A287ARU4 R-SSC-209063 https://reactome.org/PathwayBrowser/#/R-SSC-209063 Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex IEA Sus scrofa A0A287ARU4 R-SSC-209125 https://reactome.org/PathwayBrowser/#/R-SSC-209125 SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex IEA Sus scrofa A0A287ARU4 R-SSC-2130279 https://reactome.org/PathwayBrowser/#/R-SSC-2130279 Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex IEA Sus scrofa A0A287ARU4 R-SSC-2130282 https://reactome.org/PathwayBrowser/#/R-SSC-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Sus scrofa A0A287ARU4 R-SSC-2130286 https://reactome.org/PathwayBrowser/#/R-SSC-2130286 Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) IEA Sus scrofa A0A287ARU4 R-SSC-5610742 https://reactome.org/PathwayBrowser/#/R-SSC-5610742 SCF(beta-TrCP) ubiquitinates p-GLI1 IEA Sus scrofa A0A287ARU4 R-SSC-5610746 https://reactome.org/PathwayBrowser/#/R-SSC-5610746 SCF(beta-TrCP) ubiquitinates p-GLI3 IEA Sus scrofa A0A287ARU4 R-SSC-5691108 https://reactome.org/PathwayBrowser/#/R-SSC-5691108 SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 IEA Sus scrofa A0A287ARU4 R-SSC-5691167 https://reactome.org/PathwayBrowser/#/R-SSC-5691167 CUL1, SKP1, FBXL5 bind IEA Sus scrofa A0A287ARU4 R-SSC-5691176 https://reactome.org/PathwayBrowser/#/R-SSC-5691176 NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) IEA Sus scrofa A0A287ARU4 R-SSC-68946 https://reactome.org/PathwayBrowser/#/R-SSC-68946 Phosphorylated Orc1 is ubiquitinated while still associated with chromatin IEA Sus scrofa A0A287ARU4 R-SSC-8853496 https://reactome.org/PathwayBrowser/#/R-SSC-8853496 SCF:FBXL7 binds AURKA IEA Sus scrofa A0A287ARU4 R-SSC-8854041 https://reactome.org/PathwayBrowser/#/R-SSC-8854041 SCF-FBXL7 ubiquitinates AURKA IEA Sus scrofa A0A287ARU4 R-SSC-8854044 https://reactome.org/PathwayBrowser/#/R-SSC-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Sus scrofa A0A287ARU4 R-SSC-8854051 https://reactome.org/PathwayBrowser/#/R-SSC-8854051 SCF-FBXL18 ubiquitinates FBXL7 IEA Sus scrofa A0A287ARU4 R-SSC-8854052 https://reactome.org/PathwayBrowser/#/R-SSC-8854052 Formation of the SCF-FBXL7 complex IEA Sus scrofa A0A287ARU4 R-SSC-8939688 https://reactome.org/PathwayBrowser/#/R-SSC-8939688 SCF(SKP2) complex binds RUNX2 IEA Sus scrofa A0A287ARU4 R-SSC-8939706 https://reactome.org/PathwayBrowser/#/R-SSC-8939706 SCF(SKP2) polyubiquitinates RUNX2 IEA Sus scrofa A0A287ARU4 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287ARU4 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287ARU4 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287ARU4 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287ARU4 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287ARU4 R-SSC-9708517 https://reactome.org/PathwayBrowser/#/R-SSC-9708517 FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2)) IEA Sus scrofa A0A287ARU4 R-SSC-9708525 https://reactome.org/PathwayBrowser/#/R-SSC-9708525 BACH1:FBXL17 binds SCF(SKP2) complex IEA Sus scrofa A0A287ARU4 R-SSC-9762091 https://reactome.org/PathwayBrowser/#/R-SSC-9762091 NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 IEA Sus scrofa A0A287ARU4 R-SSC-9762093 https://reactome.org/PathwayBrowser/#/R-SSC-9762093 BTRC binds p-S344, 347 NFE2L2 IEA Sus scrofa A0A287ARU4 R-SSC-9762096 https://reactome.org/PathwayBrowser/#/R-SSC-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Sus scrofa A0A287ARU4 R-SSC-976991 https://reactome.org/PathwayBrowser/#/R-SSC-976991 Prolactin receptor ligands bind the prolactin receptor IEA Sus scrofa A0A287ARU4 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287ARU4 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287ARU4 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287ARU4 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287ARV8 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A287ARV8 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A287ARV8 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A287ARV8 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A287ARV8 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A287ARV8 R-SSC-9838081 https://reactome.org/PathwayBrowser/#/R-SSC-9838081 LONP1 degrades mitochondrial matrix proteins IEA Sus scrofa A0A287ARV8 R-SSC-9838093 https://reactome.org/PathwayBrowser/#/R-SSC-9838093 LONP1 binds mitochondrial matrix proteins IEA Sus scrofa A0A287ARZ1 R-SSC-429815 https://reactome.org/PathwayBrowser/#/R-SSC-429815 Formation Of Bloc-1 Complex IEA Sus scrofa A0A287ARZ1 R-SSC-432706 https://reactome.org/PathwayBrowser/#/R-SSC-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly IEA Sus scrofa A0A287ARZ1 R-SSC-432707 https://reactome.org/PathwayBrowser/#/R-SSC-432707 trans-Golgi Network Lysosomal Vesicle Scission IEA Sus scrofa A0A287ARZ1 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A287AS02 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A287AS02 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287AS02 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A287AS24 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AS29 R-SSC-482619 https://reactome.org/PathwayBrowser/#/R-SSC-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) IEA Sus scrofa A0A287AS29 R-SSC-482621 https://reactome.org/PathwayBrowser/#/R-SSC-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) IEA Sus scrofa A0A287AS29 R-SSC-6806877 https://reactome.org/PathwayBrowser/#/R-SSC-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs IEA Sus scrofa A0A287AS29 R-SSC-9748969 https://reactome.org/PathwayBrowser/#/R-SSC-9748969 NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP IEA Sus scrofa A0A287AS29 R-SSC-9748999 https://reactome.org/PathwayBrowser/#/R-SSC-9748999 NME1:2 hexamer phosphorylates 6TGDP to 6TGTP IEA Sus scrofa A0A287AS29 R-SSC-9755013 https://reactome.org/PathwayBrowser/#/R-SSC-9755013 NME1,2 hexamers phosphorylate RBV-DP IEA Sus scrofa A0A287AS32 R-SSC-3247837 https://reactome.org/PathwayBrowser/#/R-SSC-3247837 WNT ligands traffic to the Golgi IEA Sus scrofa A0A287AS32 R-SSC-3247840 https://reactome.org/PathwayBrowser/#/R-SSC-3247840 WLS binds WNT ligands in the Golgi IEA Sus scrofa A0A287AS32 R-SSC-3247843 https://reactome.org/PathwayBrowser/#/R-SSC-3247843 secretion of WNT ligands IEA Sus scrofa A0A287AS32 R-SSC-3247844 https://reactome.org/PathwayBrowser/#/R-SSC-3247844 WNT ligands traffic to the plasma membrane IEA Sus scrofa A0A287AS32 R-SSC-3781941 https://reactome.org/PathwayBrowser/#/R-SSC-3781941 WNTs are secreted in exosomes IEA Sus scrofa A0A287AS32 R-SSC-3781943 https://reactome.org/PathwayBrowser/#/R-SSC-3781943 WLS:WNT complex is internalized for maturation into exosomes IEA Sus scrofa A0A287AS32 R-SSC-5323545 https://reactome.org/PathwayBrowser/#/R-SSC-5323545 Canonical WNT signaling through the atypical receptor RYK IEA Sus scrofa A0A287AS36 R-SSC-917696 https://reactome.org/PathwayBrowser/#/R-SSC-917696 Cargo Sequestration IEA Sus scrofa A0A287AS36 R-SSC-917730 https://reactome.org/PathwayBrowser/#/R-SSC-917730 Cargo Recognition And Sorting IEA Sus scrofa A0A287AS40 R-SSC-5635854 https://reactome.org/PathwayBrowser/#/R-SSC-5635854 GLI2,3 are degraded by the proteasome IEA Sus scrofa A0A287AS40 R-SSC-5635855 https://reactome.org/PathwayBrowser/#/R-SSC-5635855 phosphorylated GLI proteins bind SPOP:CUL3:RBX1 IEA Sus scrofa A0A287AS40 R-SSC-5635856 https://reactome.org/PathwayBrowser/#/R-SSC-5635856 SPOP:CUL3:RBX1 ubiquitinates GLI2,3 IEA Sus scrofa A0A287AS48 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287AS48 R-SSC-444498 https://reactome.org/PathwayBrowser/#/R-SSC-444498 Thyrotropin-releasing hormone receptor binds thyrotropin IEA Sus scrofa A0A287AS48 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287AS48 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287AS86 R-SSC-6809680 https://reactome.org/PathwayBrowser/#/R-SSC-6809680 MTMR12 binds MTM1 IEA Sus scrofa A0A287AS86 R-SSC-6809707 https://reactome.org/PathwayBrowser/#/R-SSC-6809707 MTMR12 binds MTMR2 IEA Sus scrofa A0A287AS86 R-SSC-6809720 https://reactome.org/PathwayBrowser/#/R-SSC-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Sus scrofa A0A287AS89 R-SSC-975903 https://reactome.org/PathwayBrowser/#/R-SSC-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Sus scrofa A0A287AS91 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AS95 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287ASC7 R-SSC-190682 https://reactome.org/PathwayBrowser/#/R-SSC-190682 Connexin synthesis (generic) IEA Sus scrofa A0A287ASC8 R-SSC-426240 https://reactome.org/PathwayBrowser/#/R-SSC-426240 DAG kinase produces phosphatidic acid from DAG IEA Sus scrofa A0A287ASH2 R-SSC-913675 https://reactome.org/PathwayBrowser/#/R-SSC-913675 GALNTs transfer GalNAc to Mucins to form Tn antigens IEA Sus scrofa A0A287ASH4 R-SSC-165680 https://reactome.org/PathwayBrowser/#/R-SSC-165680 Formation of active mTORC1 complex IEA Sus scrofa A0A287ASH4 R-SSC-165692 https://reactome.org/PathwayBrowser/#/R-SSC-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Sus scrofa A0A287ASH4 R-SSC-165718 https://reactome.org/PathwayBrowser/#/R-SSC-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Sus scrofa A0A287ASH4 R-SSC-380979 https://reactome.org/PathwayBrowser/#/R-SSC-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Sus scrofa A0A287ASH4 R-SSC-447074 https://reactome.org/PathwayBrowser/#/R-SSC-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Sus scrofa A0A287ASH4 R-SSC-5653957 https://reactome.org/PathwayBrowser/#/R-SSC-5653957 Rag dimer formation IEA Sus scrofa A0A287ASH4 R-SSC-5653968 https://reactome.org/PathwayBrowser/#/R-SSC-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Sus scrofa A0A287ASH4 R-SSC-5653974 https://reactome.org/PathwayBrowser/#/R-SSC-5653974 Ragulator binds Rag dimers IEA Sus scrofa A0A287ASH4 R-SSC-5672010 https://reactome.org/PathwayBrowser/#/R-SSC-5672010 Active MTORC1 phosphorylates ULK1 IEA Sus scrofa A0A287ASH4 R-SSC-5672017 https://reactome.org/PathwayBrowser/#/R-SSC-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Sus scrofa A0A287ASH4 R-SSC-5672817 https://reactome.org/PathwayBrowser/#/R-SSC-5672817 Active MTORC1 binds the ULK1 complex IEA Sus scrofa A0A287ASH4 R-SSC-5672824 https://reactome.org/PathwayBrowser/#/R-SSC-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Sus scrofa A0A287ASH4 R-SSC-5672828 https://reactome.org/PathwayBrowser/#/R-SSC-5672828 mTORC1 phosphorylates AKT1S1 IEA Sus scrofa A0A287ASH4 R-SSC-5672843 https://reactome.org/PathwayBrowser/#/R-SSC-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Sus scrofa A0A287ASH4 R-SSC-5673768 https://reactome.org/PathwayBrowser/#/R-SSC-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Sus scrofa A0A287ASH4 R-SSC-5675790 https://reactome.org/PathwayBrowser/#/R-SSC-5675790 MTORC1 dissociates from ULK complex IEA Sus scrofa A0A287ASH4 R-SSC-8944454 https://reactome.org/PathwayBrowser/#/R-SSC-8944454 mTORC1 phosphorylates MAF1 IEA Sus scrofa A0A287ASH4 R-SSC-8944457 https://reactome.org/PathwayBrowser/#/R-SSC-8944457 MAF1 translocates to the nucleus IEA Sus scrofa A0A287ASH4 R-SSC-8952716 https://reactome.org/PathwayBrowser/#/R-SSC-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Sus scrofa A0A287ASH4 R-SSC-8952726 https://reactome.org/PathwayBrowser/#/R-SSC-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Sus scrofa A0A287ASH4 R-SSC-9639286 https://reactome.org/PathwayBrowser/#/R-SSC-9639286 RRAGC,D exchanges GTP for GDP IEA Sus scrofa A0A287ASH4 R-SSC-9640167 https://reactome.org/PathwayBrowser/#/R-SSC-9640167 RRAGA,B exchanges GDP for GTP IEA Sus scrofa A0A287ASH4 R-SSC-9640168 https://reactome.org/PathwayBrowser/#/R-SSC-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Sus scrofa A0A287ASH4 R-SSC-9640175 https://reactome.org/PathwayBrowser/#/R-SSC-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Sus scrofa A0A287ASH4 R-SSC-9640195 https://reactome.org/PathwayBrowser/#/R-SSC-9640195 RRAGA,B hydrolyzes GTP IEA Sus scrofa A0A287ASH4 R-SSC-9645598 https://reactome.org/PathwayBrowser/#/R-SSC-9645598 RRAGC,D hydrolyzes GTP IEA Sus scrofa A0A287ASH4 R-SSC-9645608 https://reactome.org/PathwayBrowser/#/R-SSC-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Sus scrofa A0A287ASH4 R-SSC-9646468 https://reactome.org/PathwayBrowser/#/R-SSC-9646468 mTORC1 binds RHEB:GTP IEA Sus scrofa A0A287ASK2 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287ASK2 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287ASK2 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287ASK2 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287ASK2 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287ASK2 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287ASK2 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287ASK2 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287ASK2 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287ASL6 R-SSC-8848023 https://reactome.org/PathwayBrowser/#/R-SSC-8848023 Activated PTK6 binds STAP2 IEA Sus scrofa A0A287ASL6 R-SSC-8848077 https://reactome.org/PathwayBrowser/#/R-SSC-8848077 PTK6 phosphorylates STAP2 IEA Sus scrofa A0A287ASL6 R-SSC-8848087 https://reactome.org/PathwayBrowser/#/R-SSC-8848087 STAP2 recruits STAT3 to PTK6 IEA Sus scrofa A0A287ASL6 R-SSC-8848124 https://reactome.org/PathwayBrowser/#/R-SSC-8848124 PTK6 phosphorylates STAT3 IEA Sus scrofa A0A287ASN4 R-SSC-6814374 https://reactome.org/PathwayBrowser/#/R-SSC-6814374 Kazrin binds periplakin IEA Sus scrofa A0A287ASN8 R-SSC-6798739 https://reactome.org/PathwayBrowser/#/R-SSC-6798739 Exocytosis of azurophil granule membrane proteins IEA Sus scrofa A0A287ASN8 R-SSC-6811417 https://reactome.org/PathwayBrowser/#/R-SSC-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi IEA Sus scrofa A0A287ASN8 R-SSC-6811418 https://reactome.org/PathwayBrowser/#/R-SSC-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane IEA Sus scrofa A0A287ASN8 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa A0A287ASN8 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa A0A287ASP2 R-SSC-879584 https://reactome.org/PathwayBrowser/#/R-SSC-879584 SLCO3A1 isoform 1 has abroad substrate specificity IEA Sus scrofa A0A287ASP9 R-SSC-8857692 https://reactome.org/PathwayBrowser/#/R-SSC-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Sus scrofa A0A287ASR0 R-SSC-1614546 https://reactome.org/PathwayBrowser/#/R-SSC-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate IEA Sus scrofa A0A287ASR0 R-SSC-372843 https://reactome.org/PathwayBrowser/#/R-SSC-372843 SLC25A10 mediates exchange of malate and phosphate IEA Sus scrofa A0A287ASR3 R-SSC-72180 https://reactome.org/PathwayBrowser/#/R-SSC-72180 Cleavage of mRNA at the 3'-end IEA Sus scrofa A0A287ASR3 R-SSC-72185 https://reactome.org/PathwayBrowser/#/R-SSC-72185 mRNA polyadenylation IEA Sus scrofa A0A287ASR3 R-SSC-72231 https://reactome.org/PathwayBrowser/#/R-SSC-72231 Formation of the Cleavage and Polyadenylation Complex IEA Sus scrofa A0A287ASR3 R-SSC-77591 https://reactome.org/PathwayBrowser/#/R-SSC-77591 Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex IEA Sus scrofa A0A287ASR3 R-SSC-77592 https://reactome.org/PathwayBrowser/#/R-SSC-77592 Cleavage of Intronless Pre-mRNA at 3'-end IEA Sus scrofa A0A287ASR3 R-SSC-77593 https://reactome.org/PathwayBrowser/#/R-SSC-77593 Cleavage and polyadenylation of Intronless Pre-mRNA IEA Sus scrofa A0A287ASR3 R-SSC-8849157 https://reactome.org/PathwayBrowser/#/R-SSC-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Sus scrofa A0A287ASR3 R-SSC-9933559 https://reactome.org/PathwayBrowser/#/R-SSC-9933559 The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1 IEA Sus scrofa A0A287ASR3 R-SSC-9933575 https://reactome.org/PathwayBrowser/#/R-SSC-9933575 MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome IEA Sus scrofa A0A287ASR3 R-SSC-9933585 https://reactome.org/PathwayBrowser/#/R-SSC-9933585 RNA exosome in PAXT:PAPOLG:TENT4A,B:ZC3H3:CBCA:polyadenylated m7GpppN-RNA:PABPN1 hydrolyzes RNA IEA Sus scrofa A0A287ASR6 R-SSC-9759522 https://reactome.org/PathwayBrowser/#/R-SSC-9759522 Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform IEA Sus scrofa A0A287ASS4 R-SSC-5252072 https://reactome.org/PathwayBrowser/#/R-SSC-5252072 AZGP1 binds PIP IEA Sus scrofa A0A287ASS7 R-SSC-9824582 https://reactome.org/PathwayBrowser/#/R-SSC-9824582 MAPK1 phosphorylates SOX10 IEA Sus scrofa A0A287ASS9 R-SSC-194642 https://reactome.org/PathwayBrowser/#/R-SSC-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Sus scrofa A0A287ASS9 R-SSC-194718 https://reactome.org/PathwayBrowser/#/R-SSC-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Sus scrofa A0A287ASU3 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287ASU4 R-SSC-156808 https://reactome.org/PathwayBrowser/#/R-SSC-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Sus scrofa A0A287ASU4 R-SSC-156823 https://reactome.org/PathwayBrowser/#/R-SSC-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Sus scrofa A0A287ASU4 R-SSC-157849 https://reactome.org/PathwayBrowser/#/R-SSC-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Sus scrofa A0A287ASU4 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A287ASU4 R-SSC-6791221 https://reactome.org/PathwayBrowser/#/R-SSC-6791221 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA IEA Sus scrofa A0A287ASU4 R-SSC-6791222 https://reactome.org/PathwayBrowser/#/R-SSC-6791222 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA IEA Sus scrofa A0A287ASU4 R-SSC-6791227 https://reactome.org/PathwayBrowser/#/R-SSC-6791227 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA IEA Sus scrofa A0A287ASU4 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa A0A287ASU4 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A287ASU4 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A287ASU4 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A287ASU4 R-SSC-72676 https://reactome.org/PathwayBrowser/#/R-SSC-72676 eIF3 and eIF1A bind to the 40S subunit IEA Sus scrofa A0A287ASU4 R-SSC-72691 https://reactome.org/PathwayBrowser/#/R-SSC-72691 Formation of the 43S pre-initiation complex IEA Sus scrofa A0A287ASU4 R-SSC-72697 https://reactome.org/PathwayBrowser/#/R-SSC-72697 Start codon recognition IEA Sus scrofa A0A287ASU4 R-SSC-8879123 https://reactome.org/PathwayBrowser/#/R-SSC-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 IEA Sus scrofa A0A287ASU4 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A287ASU4 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A287ASU4 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A287ASU4 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A287ASU4 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A287ASV6 R-SSC-6781899 https://reactome.org/PathwayBrowser/#/R-SSC-6781899 USP13 binds SIAH2 IEA Sus scrofa A0A287ASV6 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287ASV6 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287ASV6 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287ASV6 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287ASW3 R-SSC-193060 https://reactome.org/PathwayBrowser/#/R-SSC-193060 CYP19A1 hydroxylates ANDST to E1 IEA Sus scrofa A0A287ASW3 R-SSC-193143 https://reactome.org/PathwayBrowser/#/R-SSC-193143 CYP19A1 hydroxylates TEST to EST17b IEA Sus scrofa A0A287ASW3 R-SSC-9707353 https://reactome.org/PathwayBrowser/#/R-SSC-9707353 CYP19A1 binds Aromatase inhibitors IEA Sus scrofa A0A287ASW8 R-SSC-209772 https://reactome.org/PathwayBrowser/#/R-SSC-209772 Thyroxine is deiodinated to triiodothyronine IEA Sus scrofa A0A287ASX7 R-SSC-374298 https://reactome.org/PathwayBrowser/#/R-SSC-374298 Opioid receptors bind opioid peptides IEA Sus scrofa A0A287ASX7 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287ASX7 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287ASX7 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287ASX7 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A287ASY8 R-SSC-193054 https://reactome.org/PathwayBrowser/#/R-SSC-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Sus scrofa A0A287ASY8 R-SSC-193065 https://reactome.org/PathwayBrowser/#/R-SSC-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Sus scrofa A0A287ASY8 R-SSC-193101 https://reactome.org/PathwayBrowser/#/R-SSC-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Sus scrofa A0A287ASY8 R-SSC-2395512 https://reactome.org/PathwayBrowser/#/R-SSC-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Sus scrofa A0A287ASY8 R-SSC-2395517 https://reactome.org/PathwayBrowser/#/R-SSC-2395517 NADPH transfers electrons to FDXR IEA Sus scrofa A0A287ASZ5 R-SSC-159101 https://reactome.org/PathwayBrowser/#/R-SSC-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Sus scrofa A0A287ASZ5 R-SSC-72103 https://reactome.org/PathwayBrowser/#/R-SSC-72103 Formation of pre-mRNPs IEA Sus scrofa A0A287ASZ5 R-SSC-72180 https://reactome.org/PathwayBrowser/#/R-SSC-72180 Cleavage of mRNA at the 3'-end IEA Sus scrofa A0A287ASZ5 R-SSC-72185 https://reactome.org/PathwayBrowser/#/R-SSC-72185 mRNA polyadenylation IEA Sus scrofa A0A287ASZ5 R-SSC-75079 https://reactome.org/PathwayBrowser/#/R-SSC-75079 Formation of AT-AC C complex IEA Sus scrofa A0A287ASZ5 R-SSC-75081 https://reactome.org/PathwayBrowser/#/R-SSC-75081 Formation of AT-AC B Complex IEA Sus scrofa A0A287ASZ5 R-SSC-75082 https://reactome.org/PathwayBrowser/#/R-SSC-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Sus scrofa A0A287ASZ5 R-SSC-75083 https://reactome.org/PathwayBrowser/#/R-SSC-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Sus scrofa A0A287ASZ5 R-SSC-8849157 https://reactome.org/PathwayBrowser/#/R-SSC-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Sus scrofa A0A287ASZ5 R-SSC-9770119 https://reactome.org/PathwayBrowser/#/R-SSC-9770119 Formation of the Spliceosomal E complex IEA Sus scrofa A0A287ASZ5 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A287ASZ5 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287ASZ5 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A287ASZ5 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A287ASZ8 R-SSC-8848658 https://reactome.org/PathwayBrowser/#/R-SSC-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins IEA Sus scrofa A0A287AT07 R-SSC-2162186 https://reactome.org/PathwayBrowser/#/R-SSC-2162186 COQ3 methylates DeMQ10H2 IEA Sus scrofa A0A287AT07 R-SSC-2162187 https://reactome.org/PathwayBrowser/#/R-SSC-2162187 COQ6 hydroxylates DHB IEA Sus scrofa A0A287AT07 R-SSC-2162188 https://reactome.org/PathwayBrowser/#/R-SSC-2162188 COQ5 methylates MDMQ10H2 IEA Sus scrofa A0A287AT07 R-SSC-2162193 https://reactome.org/PathwayBrowser/#/R-SSC-2162193 COQ3 methylates DHDB IEA Sus scrofa A0A287AT07 R-SSC-2162194 https://reactome.org/PathwayBrowser/#/R-SSC-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Sus scrofa A0A287AT07 R-SSC-2162195 https://reactome.org/PathwayBrowser/#/R-SSC-2162195 COQ4 decarboxylates MHDB IEA Sus scrofa A0A287AT21 R-SSC-5652195 https://reactome.org/PathwayBrowser/#/R-SSC-5652195 SORD oxidizes D-sorbitol to Fru IEA Sus scrofa A0A287AT21 R-SSC-5662471 https://reactome.org/PathwayBrowser/#/R-SSC-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Sus scrofa A0A287AT23 R-SSC-1237042 https://reactome.org/PathwayBrowser/#/R-SSC-1237042 AQP1 tetramer transports CO2 from extracellular region to cytosol IEA Sus scrofa A0A287AT23 R-SSC-1247649 https://reactome.org/PathwayBrowser/#/R-SSC-1247649 AQP1 tetramer transports CO2 from cytosol to extracellular region IEA Sus scrofa A0A287AT23 R-SSC-432010 https://reactome.org/PathwayBrowser/#/R-SSC-432010 Aquaporin-1 passively transports water into cell IEA Sus scrofa A0A287AT23 R-SSC-432054 https://reactome.org/PathwayBrowser/#/R-SSC-432054 Aquaporin-1 passively transports water out of cell IEA Sus scrofa A0A287AT23 R-SSC-507868 https://reactome.org/PathwayBrowser/#/R-SSC-507868 Aquaporins passively transport water into cells IEA Sus scrofa A0A287AT23 R-SSC-507870 https://reactome.org/PathwayBrowser/#/R-SSC-507870 Aquaporins passively transport water out of cells IEA Sus scrofa A0A287AT33 R-SSC-198955 https://reactome.org/PathwayBrowser/#/R-SSC-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Sus scrofa A0A287AT33 R-SSC-202165 https://reactome.org/PathwayBrowser/#/R-SSC-202165 Phosphorylation of ITAM motifs in CD3 complexes IEA Sus scrofa A0A287AT33 R-SSC-202168 https://reactome.org/PathwayBrowser/#/R-SSC-202168 Phosphorylation of ZAP-70 by Lck IEA Sus scrofa A0A287AT33 R-SSC-202174 https://reactome.org/PathwayBrowser/#/R-SSC-202174 Activation of ZAP-70 IEA Sus scrofa A0A287AT33 R-SSC-202214 https://reactome.org/PathwayBrowser/#/R-SSC-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Sus scrofa A0A287AT33 R-SSC-202216 https://reactome.org/PathwayBrowser/#/R-SSC-202216 Phosphorylation of SLP-76 IEA Sus scrofa A0A287AT33 R-SSC-202233 https://reactome.org/PathwayBrowser/#/R-SSC-202233 Inactivation of Lck by Csk IEA Sus scrofa A0A287AT33 R-SSC-202245 https://reactome.org/PathwayBrowser/#/R-SSC-202245 Phosphorylation of TBSMs in LAT IEA Sus scrofa A0A287AT33 R-SSC-202248 https://reactome.org/PathwayBrowser/#/R-SSC-202248 Phosphorylation of PLC-gamma1 IEA Sus scrofa A0A287AT33 R-SSC-202291 https://reactome.org/PathwayBrowser/#/R-SSC-202291 Activation of Lck IEA Sus scrofa A0A287AT33 R-SSC-202307 https://reactome.org/PathwayBrowser/#/R-SSC-202307 Change of PKC theta conformation IEA Sus scrofa A0A287AT33 R-SSC-389758 https://reactome.org/PathwayBrowser/#/R-SSC-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases IEA Sus scrofa A0A287AT33 R-SSC-8850326 https://reactome.org/PathwayBrowser/#/R-SSC-8850326 TCR binds self-lipid-based antigen via CD1 IEA Sus scrofa A0A287AT33 R-SSC-8850356 https://reactome.org/PathwayBrowser/#/R-SSC-8850356 TCR binds microbial lipid-based antigen via CD1 IEA Sus scrofa A0A287AT33 R-SSC-8852200 https://reactome.org/PathwayBrowser/#/R-SSC-8852200 Inactivation of LCK by PTPN22 IEA Sus scrofa A0A287AT33 R-SSC-8855381 https://reactome.org/PathwayBrowser/#/R-SSC-8855381 PTPN22 dephosphorylates ZAP70 IEA Sus scrofa A0A287AT36 R-SSC-173709 https://reactome.org/PathwayBrowser/#/R-SSC-173709 C7 binds C5b:C6 IEA Sus scrofa A0A287AT36 R-SSC-173720 https://reactome.org/PathwayBrowser/#/R-SSC-173720 C5b:C6:C7 translocates to the plasma membrane IEA Sus scrofa A0A287AT36 R-SSC-173723 https://reactome.org/PathwayBrowser/#/R-SSC-173723 C8 binds C5b:C6:C7 IEA Sus scrofa A0A287AT36 R-SSC-173725 https://reactome.org/PathwayBrowser/#/R-SSC-173725 C9 binds C5b:C6:C7:C8 IEA Sus scrofa A0A287AT36 R-SSC-2530429 https://reactome.org/PathwayBrowser/#/R-SSC-2530429 Formation of soluble VTN:C5b-C9 IEA Sus scrofa A0A287AT36 R-SSC-2530445 https://reactome.org/PathwayBrowser/#/R-SSC-2530445 CD59 inhibits MAC formation IEA Sus scrofa A0A287AT36 R-SSC-8852580 https://reactome.org/PathwayBrowser/#/R-SSC-8852580 Clusterin binds C5b-C7, C8, C9 IEA Sus scrofa A0A287AT37 R-SSC-190682 https://reactome.org/PathwayBrowser/#/R-SSC-190682 Connexin synthesis (generic) IEA Sus scrofa A0A287AT39 R-SSC-449911 https://reactome.org/PathwayBrowser/#/R-SSC-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] IEA Sus scrofa A0A287AT82 R-SSC-2855020 https://reactome.org/PathwayBrowser/#/R-SSC-2855020 RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol IEA Sus scrofa A0A287AT83 R-SSC-156808 https://reactome.org/PathwayBrowser/#/R-SSC-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Sus scrofa A0A287AT83 R-SSC-156823 https://reactome.org/PathwayBrowser/#/R-SSC-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Sus scrofa A0A287AT83 R-SSC-157849 https://reactome.org/PathwayBrowser/#/R-SSC-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Sus scrofa A0A287AT83 R-SSC-165777 https://reactome.org/PathwayBrowser/#/R-SSC-165777 Phosphorylation and activation of eIF4B by activated S6K1 IEA Sus scrofa A0A287AT83 R-SSC-429955 https://reactome.org/PathwayBrowser/#/R-SSC-429955 CCR4-NOT complex deadenylates mRNA IEA Sus scrofa A0A287AT83 R-SSC-429992 https://reactome.org/PathwayBrowser/#/R-SSC-429992 PARN deadenylates mRNA IEA Sus scrofa A0A287AT83 R-SSC-430021 https://reactome.org/PathwayBrowser/#/R-SSC-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Sus scrofa A0A287AT83 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa A0A287AT83 R-SSC-72697 https://reactome.org/PathwayBrowser/#/R-SSC-72697 Start codon recognition IEA Sus scrofa A0A287AT99 R-SSC-196955 https://reactome.org/PathwayBrowser/#/R-SSC-196955 2xENPP1 hydrolyzes FAD to FMN IEA Sus scrofa A0A287ATB1 R-SSC-8948775 https://reactome.org/PathwayBrowser/#/R-SSC-8948775 MKRN1 polyubiquitinates PTEN IEA Sus scrofa A0A287ATB1 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287ATB1 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287ATB1 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287ATB1 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287ATB3 R-SSC-8858270 https://reactome.org/PathwayBrowser/#/R-SSC-8858270 HILPDA binds lipid droplets IEA Sus scrofa A0A287ATC0 R-SSC-6798739 https://reactome.org/PathwayBrowser/#/R-SSC-6798739 Exocytosis of azurophil granule membrane proteins IEA Sus scrofa A0A287ATC0 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A287ATC0 R-SSC-6800426 https://reactome.org/PathwayBrowser/#/R-SSC-6800426 Exocytosis of ficolin-rich granule membrane proteins IEA Sus scrofa A0A287ATC4 R-SSC-75079 https://reactome.org/PathwayBrowser/#/R-SSC-75079 Formation of AT-AC C complex IEA Sus scrofa A0A287ATC4 R-SSC-75081 https://reactome.org/PathwayBrowser/#/R-SSC-75081 Formation of AT-AC B Complex IEA Sus scrofa A0A287ATC4 R-SSC-75082 https://reactome.org/PathwayBrowser/#/R-SSC-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Sus scrofa A0A287ATC4 R-SSC-75083 https://reactome.org/PathwayBrowser/#/R-SSC-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Sus scrofa A0A287ATC4 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287ATC5 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A287ATC5 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A287ATC5 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287ATC5 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287ATC5 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287ATC5 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287ATC5 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287ATC5 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287ATC5 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287ATC5 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287ATC5 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287ATE7 R-SSC-111962 https://reactome.org/PathwayBrowser/#/R-SSC-111962 PDE4A,C,D hydrolyse cAMP IEA Sus scrofa A0A287ATE7 R-SSC-418553 https://reactome.org/PathwayBrowser/#/R-SSC-418553 cAMP degradation by Phosphodiesterases IEA Sus scrofa A0A287ATE7 R-SSC-9865226 https://reactome.org/PathwayBrowser/#/R-SSC-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Sus scrofa A0A287ATF0 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287ATF0 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287ATF0 R-SSC-8852509 https://reactome.org/PathwayBrowser/#/R-SSC-8852509 CL-LK binds carbohydrates on target cell surface IEA Sus scrofa A0A287ATF2 R-SSC-351877 https://reactome.org/PathwayBrowser/#/R-SSC-351877 Caspase-mediated cleavage of Desmoglein 2 IEA Sus scrofa A0A287ATF2 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A287ATF2 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A287ATF2 R-SSC-6814695 https://reactome.org/PathwayBrowser/#/R-SSC-6814695 PERP binds desmosomes IEA Sus scrofa A0A287ATF2 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A287ATF2 R-SSC-9014294 https://reactome.org/PathwayBrowser/#/R-SSC-9014294 RAC2 binds effectors at the plasma membrane IEA Sus scrofa A0A287ATF2 R-SSC-9014449 https://reactome.org/PathwayBrowser/#/R-SSC-9014449 RHOG binds effectors at the plasma membrane IEA Sus scrofa A0A287ATF2 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa A0A287ATF5 R-SSC-451283 https://reactome.org/PathwayBrowser/#/R-SSC-451283 kainate receptor binds glutamate IEA Sus scrofa A0A287ATF5 R-SSC-451311 https://reactome.org/PathwayBrowser/#/R-SSC-451311 Activation of Ca-permeable Kainate receptors IEA Sus scrofa A0A287ATF5 R-SSC-500708 https://reactome.org/PathwayBrowser/#/R-SSC-500708 GRIK3 homomer binds glutamate IEA Sus scrofa A0A287ATF5 R-SSC-500717 https://reactome.org/PathwayBrowser/#/R-SSC-500717 Activation of GRIK3 homomer IEA Sus scrofa A0A287ATH4 R-SSC-1667005 https://reactome.org/PathwayBrowser/#/R-SSC-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Sus scrofa A0A287ATH4 R-SSC-1678694 https://reactome.org/PathwayBrowser/#/R-SSC-1678694 Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans IEA Sus scrofa A0A287ATH4 R-SSC-1878002 https://reactome.org/PathwayBrowser/#/R-SSC-1878002 XYLTs transfer Xyl to core protein IEA Sus scrofa A0A287ATH4 R-SSC-1889955 https://reactome.org/PathwayBrowser/#/R-SSC-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Sus scrofa A0A287ATH4 R-SSC-1889978 https://reactome.org/PathwayBrowser/#/R-SSC-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Sus scrofa A0A287ATH4 R-SSC-1889981 https://reactome.org/PathwayBrowser/#/R-SSC-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Sus scrofa A0A287ATH4 R-SSC-2022851 https://reactome.org/PathwayBrowser/#/R-SSC-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Sus scrofa A0A287ATH4 R-SSC-2022856 https://reactome.org/PathwayBrowser/#/R-SSC-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Sus scrofa A0A287ATH4 R-SSC-2022860 https://reactome.org/PathwayBrowser/#/R-SSC-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Sus scrofa A0A287ATH4 R-SSC-2022887 https://reactome.org/PathwayBrowser/#/R-SSC-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Sus scrofa A0A287ATH4 R-SSC-2022919 https://reactome.org/PathwayBrowser/#/R-SSC-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Sus scrofa A0A287ATH4 R-SSC-2024084 https://reactome.org/PathwayBrowser/#/R-SSC-2024084 HS-GAGs translocate to the lysosome for degradation IEA Sus scrofa A0A287ATH4 R-SSC-2024108 https://reactome.org/PathwayBrowser/#/R-SSC-2024108 Some HSPGs are secreted to the plasma membrane IEA Sus scrofa A0A287ATH4 R-SSC-2076383 https://reactome.org/PathwayBrowser/#/R-SSC-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Sus scrofa A0A287ATH4 R-SSC-2076392 https://reactome.org/PathwayBrowser/#/R-SSC-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Sus scrofa A0A287ATH4 R-SSC-2076419 https://reactome.org/PathwayBrowser/#/R-SSC-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Sus scrofa A0A287ATH4 R-SSC-2076508 https://reactome.org/PathwayBrowser/#/R-SSC-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Sus scrofa A0A287ATH4 R-SSC-2076611 https://reactome.org/PathwayBrowser/#/R-SSC-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Sus scrofa A0A287ATH4 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa A0A287ATH4 R-SSC-2423785 https://reactome.org/PathwayBrowser/#/R-SSC-2423785 CR:atREs binds apoE and HSPG IEA Sus scrofa A0A287ATH4 R-SSC-428518 https://reactome.org/PathwayBrowser/#/R-SSC-428518 Glypican-1 (GPC1) binds SLIT2 IEA Sus scrofa A0A287ATH4 R-SSC-8870732 https://reactome.org/PathwayBrowser/#/R-SSC-8870732 PSGs bind proteoglycans and TGF-beta1 IEA Sus scrofa A0A287ATH4 R-SSC-9638064 https://reactome.org/PathwayBrowser/#/R-SSC-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Sus scrofa A0A287ATM3 R-SSC-427555 https://reactome.org/PathwayBrowser/#/R-SSC-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Sus scrofa A0A287ATN5 R-SSC-5696839 https://reactome.org/PathwayBrowser/#/R-SSC-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF IEA Sus scrofa A0A287ATN5 R-SSC-6801456 https://reactome.org/PathwayBrowser/#/R-SSC-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF IEA Sus scrofa A0A287ATP3 R-SSC-1013012 https://reactome.org/PathwayBrowser/#/R-SSC-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Sus scrofa A0A287ATP3 R-SSC-1013020 https://reactome.org/PathwayBrowser/#/R-SSC-1013020 Activation of GIRK/Kir3 Channels IEA Sus scrofa A0A287ATP3 R-SSC-1296045 https://reactome.org/PathwayBrowser/#/R-SSC-1296045 Activation of Potassium transport channels IEA Sus scrofa A0A287ATU4 R-SSC-450394 https://reactome.org/PathwayBrowser/#/R-SSC-450394 p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta IEA Sus scrofa A0A287ATU4 R-SSC-450400 https://reactome.org/PathwayBrowser/#/R-SSC-450400 ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs IEA Sus scrofa A0A287ATU4 R-SSC-450431 https://reactome.org/PathwayBrowser/#/R-SSC-450431 ZFP36 (TTP) recruits RNA degradation activities IEA Sus scrofa A0A287ATU4 R-SSC-450463 https://reactome.org/PathwayBrowser/#/R-SSC-450463 MK2 phosphorylates ZFP36 (Tristetraproline, TTP) IEA Sus scrofa A0A287ATU4 R-SSC-5624948 https://reactome.org/PathwayBrowser/#/R-SSC-5624948 KIF17 enters the cilium IEA Sus scrofa A0A287ATU4 R-SSC-5624951 https://reactome.org/PathwayBrowser/#/R-SSC-5624951 TNPO1 binds KIF17 dimer IEA Sus scrofa A0A287ATV4 R-SSC-3858475 https://reactome.org/PathwayBrowser/#/R-SSC-3858475 ppDVL recruits RAC IEA Sus scrofa A0A287ATV4 R-SSC-9018804 https://reactome.org/PathwayBrowser/#/R-SSC-9018804 RAC3 GEFs activate RAC3 IEA Sus scrofa A0A287ATV4 R-SSC-9018806 https://reactome.org/PathwayBrowser/#/R-SSC-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Sus scrofa A0A287ATV4 R-SSC-9018807 https://reactome.org/PathwayBrowser/#/R-SSC-9018807 RAC3 GDIs block activation of RAC3 IEA Sus scrofa A0A287ATV4 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa A0A287ATV4 R-SSC-9714691 https://reactome.org/PathwayBrowser/#/R-SSC-9714691 RAC3 binds ER effectors IEA Sus scrofa A0A287ATV4 R-SSC-9714694 https://reactome.org/PathwayBrowser/#/R-SSC-9714694 RAC3 translocates to the endoplasmic reticulum membrane IEA Sus scrofa A0A287ATW7 R-SSC-2076611 https://reactome.org/PathwayBrowser/#/R-SSC-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Sus scrofa A0A287ATW9 R-SSC-5696408 https://reactome.org/PathwayBrowser/#/R-SSC-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Sus scrofa A0A287ATZ7 R-SSC-173542 https://reactome.org/PathwayBrowser/#/R-SSC-173542 SMURF2 ubiquitinates SMAD2 IEA Sus scrofa A0A287ATZ7 R-SSC-178208 https://reactome.org/PathwayBrowser/#/R-SSC-178208 SMAD7 binds to SMURF2 IEA Sus scrofa A0A287ATZ7 R-SSC-201445 https://reactome.org/PathwayBrowser/#/R-SSC-201445 Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8 IEA Sus scrofa A0A287ATZ7 R-SSC-201821 https://reactome.org/PathwayBrowser/#/R-SSC-201821 I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated IEA Sus scrofa A0A287ATZ7 R-SSC-2176445 https://reactome.org/PathwayBrowser/#/R-SSC-2176445 SMURF2 binds SMAD2 IEA Sus scrofa A0A287ATZ7 R-SSC-2179274 https://reactome.org/PathwayBrowser/#/R-SSC-2179274 SMURF2 binds SMAD3 phosphorylated in the linker region IEA Sus scrofa A0A287ATZ7 R-SSC-2179276 https://reactome.org/PathwayBrowser/#/R-SSC-2179276 SMURF2 monoubiquitinates SMAD3 IEA Sus scrofa A0A287ATZ7 R-SSC-4608852 https://reactome.org/PathwayBrowser/#/R-SSC-4608852 SMURF1/2 ubiquitinates PRICKLE1 IEA Sus scrofa A0A287ATZ7 R-SSC-4608854 https://reactome.org/PathwayBrowser/#/R-SSC-4608854 SMURF1/2 are recruited to the DVL2:PARD6A complex IEA Sus scrofa A0A287ATZ7 R-SSC-4641129 https://reactome.org/PathwayBrowser/#/R-SSC-4641129 AXIN is ubiquitinated by SMURF2 IEA Sus scrofa A0A287ATZ7 R-SSC-4641134 https://reactome.org/PathwayBrowser/#/R-SSC-4641134 SMURF2 binds AXIN IEA Sus scrofa A0A287ATZ7 R-SSC-4641256 https://reactome.org/PathwayBrowser/#/R-SSC-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Sus scrofa A0A287ATZ7 R-SSC-5635865 https://reactome.org/PathwayBrowser/#/R-SSC-5635865 SMURF1/2 dissociates from ub-PTCH1 IEA Sus scrofa A0A287ATZ7 R-SSC-6781764 https://reactome.org/PathwayBrowser/#/R-SSC-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Sus scrofa A0A287ATZ7 R-SSC-8952419 https://reactome.org/PathwayBrowser/#/R-SSC-8952419 SMURFs ubiquitinate RUNX3 IEA Sus scrofa A0A287ATZ7 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287ATZ7 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287ATZ7 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287ATZ7 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AU00 R-SSC-1296127 https://reactome.org/PathwayBrowser/#/R-SSC-1296127 Activation of voltage gated Potassium channels IEA Sus scrofa A0A287AU00 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A287AU00 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A287AU23 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A287AU23 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287AU29 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287AU31 R-SSC-6786155 https://reactome.org/PathwayBrowser/#/R-SSC-6786155 POLN binds ICL-DNA IEA Sus scrofa A0A287AU31 R-SSC-6786166 https://reactome.org/PathwayBrowser/#/R-SSC-6786166 Translesion synthesis across unhooked ICL by POLN IEA Sus scrofa A0A287AU43 R-SSC-4641205 https://reactome.org/PathwayBrowser/#/R-SSC-4641205 RSPO:LGR binds ZNRF3 IEA Sus scrofa A0A287AU43 R-SSC-4641206 https://reactome.org/PathwayBrowser/#/R-SSC-4641206 RSPOs bind LGRs IEA Sus scrofa A0A287AU43 R-SSC-4641246 https://reactome.org/PathwayBrowser/#/R-SSC-4641246 ZNRF3 autoubiquitinates to promote its internalization IEA Sus scrofa A0A287AU44 R-SSC-1675773 https://reactome.org/PathwayBrowser/#/R-SSC-1675773 PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane IEA Sus scrofa A0A287AU44 R-SSC-1676082 https://reactome.org/PathwayBrowser/#/R-SSC-1676082 PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane IEA Sus scrofa A0A287AU44 R-SSC-1676145 https://reactome.org/PathwayBrowser/#/R-SSC-1676145 PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane IEA Sus scrofa A0A287AU44 R-SSC-399936 https://reactome.org/PathwayBrowser/#/R-SSC-399936 Inhibition of integrin activation by sequestering PIP5KIgamma IEA Sus scrofa A0A287AU44 R-SSC-8868066 https://reactome.org/PathwayBrowser/#/R-SSC-8868066 PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 IEA Sus scrofa A0A287AU51 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AU51 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287AU51 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AU51 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AU51 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AU51 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AU51 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287AU51 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AU51 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AU64 R-SSC-72103 https://reactome.org/PathwayBrowser/#/R-SSC-72103 Formation of pre-mRNPs IEA Sus scrofa A0A287AU64 R-SSC-9770119 https://reactome.org/PathwayBrowser/#/R-SSC-9770119 Formation of the Spliceosomal E complex IEA Sus scrofa A0A287AU64 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A287AU64 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287AU64 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A287AU64 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A287AU85 R-SSC-176298 https://reactome.org/PathwayBrowser/#/R-SSC-176298 Activation of claspin IEA Sus scrofa A0A287AU85 R-SSC-176318 https://reactome.org/PathwayBrowser/#/R-SSC-176318 Loading of claspin onto DNA during replication origin firing IEA Sus scrofa A0A287AU85 R-SSC-68914 https://reactome.org/PathwayBrowser/#/R-SSC-68914 DNA polymerase alpha:primase binds at the origin IEA Sus scrofa A0A287AU85 R-SSC-68916 https://reactome.org/PathwayBrowser/#/R-SSC-68916 DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin IEA Sus scrofa A0A287AU85 R-SSC-68917 https://reactome.org/PathwayBrowser/#/R-SSC-68917 Cdc45 associates with the pre-replicative complex at the origin IEA Sus scrofa A0A287AU85 R-SSC-68918 https://reactome.org/PathwayBrowser/#/R-SSC-68918 CDK and DDK associate with the Mcm10:pre-replicative complex IEA Sus scrofa A0A287AU85 R-SSC-68919 https://reactome.org/PathwayBrowser/#/R-SSC-68919 Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 IEA Sus scrofa A0A287AU85 R-SSC-68940 https://reactome.org/PathwayBrowser/#/R-SSC-68940 Cdt1 is displaced from the pre-replicative complex IEA Sus scrofa A0A287AU85 R-SSC-68944 https://reactome.org/PathwayBrowser/#/R-SSC-68944 Orc1 is phosphorylated by cyclin A/CDK2 IEA Sus scrofa A0A287AU85 R-SSC-68954 https://reactome.org/PathwayBrowser/#/R-SSC-68954 Mcm2-7 is phosphorylated by DDK IEA Sus scrofa A0A287AU85 R-SSC-68960 https://reactome.org/PathwayBrowser/#/R-SSC-68960 DNA polymerase epsilon binds at the origin IEA Sus scrofa A0A287AU85 R-SSC-69019 https://reactome.org/PathwayBrowser/#/R-SSC-69019 Mcm4,6,7 trimer forms and associates with the replication fork IEA Sus scrofa A0A287AU85 R-SSC-9749253 https://reactome.org/PathwayBrowser/#/R-SSC-9749253 Formation of MCM2-7 complex IEA Sus scrofa A0A287AU85 R-SSC-9757257 https://reactome.org/PathwayBrowser/#/R-SSC-9757257 MCM4, MCM6 and MCM7 form a heterotrimer IEA Sus scrofa A0A287AU85 R-SSC-9757258 https://reactome.org/PathwayBrowser/#/R-SSC-9757258 MCM2 binds MCM4:MCM6:MCM7 heterotrimer IEA Sus scrofa A0A287AU92 R-SSC-9937298 https://reactome.org/PathwayBrowser/#/R-SSC-9937298 DHRSX oxidizes polyprenol to polyprenal IEA Sus scrofa A0A287AU92 R-SSC-9937340 https://reactome.org/PathwayBrowser/#/R-SSC-9937340 DHRSX reduces dolichal to dolichol IEA Sus scrofa A0A287AU93 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287AU93 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287AU93 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287AU93 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287AU93 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287AU93 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287AU93 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287AU93 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287AU93 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287AU93 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AU93 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287AU93 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287AU93 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287AU93 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287AU93 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287AU93 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287AU93 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287AU93 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287AU93 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287AU93 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287AU93 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287AU93 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287AU93 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287AU93 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287AU93 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287AU93 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287AU93 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287AU93 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287AU93 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287AU93 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287AU93 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287AU93 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287AU93 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287AU93 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287AU93 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287AU93 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287AU93 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287AU93 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287AU93 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287AU93 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287AU93 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287AU93 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287AU93 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287AU93 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287AU93 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287AU93 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287AU93 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287AUA7 R-SSC-1251997 https://reactome.org/PathwayBrowser/#/R-SSC-1251997 Cleavage of ERBB4m80 by gamma-scretase complex IEA Sus scrofa A0A287AUA7 R-SSC-193682 https://reactome.org/PathwayBrowser/#/R-SSC-193682 gamma-secretase cleaves the p75NTR transmembrane domain IEA Sus scrofa A0A287AUA7 R-SSC-3928656 https://reactome.org/PathwayBrowser/#/R-SSC-3928656 gamma-secretase cleaves EPHB2 IEA Sus scrofa A0A287AUA7 R-SSC-9839376 https://reactome.org/PathwayBrowser/#/R-SSC-9839376 TGFBR3(784-851) degradation IEA Sus scrofa A0A287AUC7 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287AUC7 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AUC7 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AUE4 R-SSC-8852129 https://reactome.org/PathwayBrowser/#/R-SSC-8852129 UBA1 conjugates ubiquitin to cytosolic E2 enzymes IEA Sus scrofa A0A287AUE4 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AUE4 R-SSC-983152 https://reactome.org/PathwayBrowser/#/R-SSC-983152 Transfer of ubiquitin from E1 to E2 IEA Sus scrofa A0A287AUE4 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AUE4 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AUF3 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287AUF5 R-SSC-1234159 https://reactome.org/PathwayBrowser/#/R-SSC-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Sus scrofa A0A287AUF5 R-SSC-1234163 https://reactome.org/PathwayBrowser/#/R-SSC-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Sus scrofa A0A287AUF5 R-SSC-1234173 https://reactome.org/PathwayBrowser/#/R-SSC-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Sus scrofa A0A287AUF5 R-SSC-1234177 https://reactome.org/PathwayBrowser/#/R-SSC-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Sus scrofa A0A287AUF5 R-SSC-1234183 https://reactome.org/PathwayBrowser/#/R-SSC-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Sus scrofa A0A287AUG2 R-SSC-140978 https://reactome.org/PathwayBrowser/#/R-SSC-140978 TRADD:TRAF2:RIP1 binds FADD IEA Sus scrofa A0A287AUG2 R-SSC-5357776 https://reactome.org/PathwayBrowser/#/R-SSC-5357776 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG IEA Sus scrofa A0A287AUG2 R-SSC-5357831 https://reactome.org/PathwayBrowser/#/R-SSC-5357831 CHUK, IKBKB phosphorylate CYLD at S418 IEA Sus scrofa A0A287AUG2 R-SSC-5357845 https://reactome.org/PathwayBrowser/#/R-SSC-5357845 K63polyUb-RIPK1 is deubiquitinated IEA Sus scrofa A0A287AUG2 R-SSC-5357860 https://reactome.org/PathwayBrowser/#/R-SSC-5357860 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex IEA Sus scrofa A0A287AUG2 R-SSC-5357928 https://reactome.org/PathwayBrowser/#/R-SSC-5357928 CLIP3 and CYLD bind TNF signaling complex IEA Sus scrofa A0A287AUG2 R-SSC-5696627 https://reactome.org/PathwayBrowser/#/R-SSC-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Sus scrofa A0A287AUG2 R-SSC-83582 https://reactome.org/PathwayBrowser/#/R-SSC-83582 TRADD:TRAF2:RIP1 dissociates from TNF-α:TNFR1 IEA Sus scrofa A0A287AUG2 R-SSC-936390 https://reactome.org/PathwayBrowser/#/R-SSC-936390 CYLD mediated deubiquitination of DDX58 (RIG-I) IEA Sus scrofa A0A287AUG2 R-SSC-9793680 https://reactome.org/PathwayBrowser/#/R-SSC-9793680 OPTN binds polyUb-RIPK1 within the TNFR1 complex IEA Sus scrofa A0A287AUG2 R-SSC-9796379 https://reactome.org/PathwayBrowser/#/R-SSC-9796379 CYLD:SPATA2:LUBAC binds TNFR1 signaling complex IEA Sus scrofa A0A287AUG2 R-SSC-9815507 https://reactome.org/PathwayBrowser/#/R-SSC-9815507 MIB2 ubiquitinates CYLD at K338, K530 IEA Sus scrofa A0A287AUG2 R-SSC-9815510 https://reactome.org/PathwayBrowser/#/R-SSC-9815510 MIB2 binds CYLD IEA Sus scrofa A0A287AUG2 R-SSC-9817362 https://reactome.org/PathwayBrowser/#/R-SSC-9817362 SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex IEA Sus scrofa A0A287AUG2 R-SSC-9817397 https://reactome.org/PathwayBrowser/#/R-SSC-9817397 TBK1, IKBKE phosphorylate RIPK1 at T189 IEA Sus scrofa A0A287AUG2 R-SSC-9817400 https://reactome.org/PathwayBrowser/#/R-SSC-9817400 CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex IEA Sus scrofa A0A287AUG2 R-SSC-9817411 https://reactome.org/PathwayBrowser/#/R-SSC-9817411 TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex IEA Sus scrofa A0A287AUG2 R-SSC-9818789 https://reactome.org/PathwayBrowser/#/R-SSC-9818789 CHUK, IKBKB phosphorylate RIPK1 at S25 IEA Sus scrofa A0A287AUG2 R-SSC-9818975 https://reactome.org/PathwayBrowser/#/R-SSC-9818975 CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex IEA Sus scrofa A0A287AUG2 R-SSC-9824874 https://reactome.org/PathwayBrowser/#/R-SSC-9824874 OPTN recruits CYLD to the TNFR1 complex IEA Sus scrofa A0A287AUH5 R-SSC-199202 https://reactome.org/PathwayBrowser/#/R-SSC-199202 Phosphopantetheine conjugation of the ACP domain of FAS IEA Sus scrofa A0A287AUH8 R-SSC-418436 https://reactome.org/PathwayBrowser/#/R-SSC-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Sus scrofa A0A287AUH8 R-SSC-9033235 https://reactome.org/PathwayBrowser/#/R-SSC-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A287AUH8 R-SSC-9033236 https://reactome.org/PathwayBrowser/#/R-SSC-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Sus scrofa A0A287AUI1 R-SSC-6809764 https://reactome.org/PathwayBrowser/#/R-SSC-6809764 SBF1 binds MTMR2 IEA Sus scrofa A0A287AUI1 R-SSC-6809777 https://reactome.org/PathwayBrowser/#/R-SSC-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Sus scrofa A0A287AUI1 R-SSC-6809778 https://reactome.org/PathwayBrowser/#/R-SSC-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Sus scrofa A0A287AUI9 R-SSC-2028589 https://reactome.org/PathwayBrowser/#/R-SSC-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Sus scrofa A0A287AUI9 R-SSC-2028591 https://reactome.org/PathwayBrowser/#/R-SSC-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 IEA Sus scrofa A0A287AUI9 R-SSC-2028635 https://reactome.org/PathwayBrowser/#/R-SSC-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Sus scrofa A0A287AUI9 R-SSC-2028673 https://reactome.org/PathwayBrowser/#/R-SSC-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Sus scrofa A0A287AUI9 R-SSC-2028675 https://reactome.org/PathwayBrowser/#/R-SSC-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Sus scrofa A0A287AUI9 R-SSC-2028697 https://reactome.org/PathwayBrowser/#/R-SSC-2028697 Cleavage of p-STK3 (p-MST2) by caspase 3 IEA Sus scrofa A0A287AUJ0 R-SSC-1362408 https://reactome.org/PathwayBrowser/#/R-SSC-1362408 FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster IEA Sus scrofa A0A287AUJ0 R-SSC-1362416 https://reactome.org/PathwayBrowser/#/R-SSC-1362416 Frataxin binds iron IEA Sus scrofa A0A287AUJ0 R-SSC-9854984 https://reactome.org/PathwayBrowser/#/R-SSC-9854984 Transfer of Fe-S clusters to SDHB IEA Sus scrofa A0A287AUJ0 R-SSC-9866272 https://reactome.org/PathwayBrowser/#/R-SSC-9866272 2Fe-2S is inserted in UQCRFS1 IEA Sus scrofa A0A287AUJ3 R-SSC-6797974 https://reactome.org/PathwayBrowser/#/R-SSC-6797974 LRRTMs bind NRXNs IEA Sus scrofa A0A287AUM7 R-SSC-2584246 https://reactome.org/PathwayBrowser/#/R-SSC-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Sus scrofa A0A287AUM7 R-SSC-4086392 https://reactome.org/PathwayBrowser/#/R-SSC-4086392 PDE6 hydrolyses cGMP to GMP IEA Sus scrofa A0A287AUM7 R-SSC-74059 https://reactome.org/PathwayBrowser/#/R-SSC-74059 PDE6 hydrolyses cGMP to GMP IEA Sus scrofa A0A287AUN9 R-SSC-3295580 https://reactome.org/PathwayBrowser/#/R-SSC-3295580 TRPM4,5 transport extracellular Na+ to cytosol IEA Sus scrofa A0A287AUP9 R-SSC-110248 https://reactome.org/PathwayBrowser/#/R-SSC-110248 Cleavage of 3-methyladenine by MPG glycosylase IEA Sus scrofa A0A287AUP9 R-SSC-110250 https://reactome.org/PathwayBrowser/#/R-SSC-110250 Cleavage of ethenoadenine by MPG glycosylase IEA Sus scrofa A0A287AUP9 R-SSC-110251 https://reactome.org/PathwayBrowser/#/R-SSC-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Sus scrofa A0A287AUP9 R-SSC-110356 https://reactome.org/PathwayBrowser/#/R-SSC-110356 Displacement of MPG glycosylase by APEX1 at the AP site IEA Sus scrofa A0A287AUQ0 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287AUR4 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287AUR4 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287AUR4 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287AUR4 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287AUR4 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287AUR4 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287AUR4 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287AUR4 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287AUR4 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287AUR4 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AUR4 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287AUR4 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287AUR4 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287AUR4 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287AUR4 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287AUR4 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287AUR4 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287AUR4 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287AUR4 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287AUR4 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287AUR4 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287AUR4 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287AUR4 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287AUR4 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287AUR4 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287AUR4 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287AUR4 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287AUR4 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287AUR4 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287AUR4 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287AUR4 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287AUR4 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287AUR4 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287AUR4 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287AUR4 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287AUR4 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287AUR4 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287AUR4 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287AUR4 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287AUR4 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287AUR4 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287AUR4 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287AUR4 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287AUR4 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287AUR4 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287AUR4 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287AUR4 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287AUS4 R-SSC-373075 https://reactome.org/PathwayBrowser/#/R-SSC-373075 Metabotropic glutamate receptors bind glutamate IEA Sus scrofa A0A287AUS4 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287AUS4 R-SSC-6794347 https://reactome.org/PathwayBrowser/#/R-SSC-6794347 Homer1,2,3 dimerizes IEA Sus scrofa A0A287AUS4 R-SSC-6794355 https://reactome.org/PathwayBrowser/#/R-SSC-6794355 Homer1,2,3 binds mGluR1a,5 IEA Sus scrofa A0A287AUS4 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287AUS4 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287AUT3 R-SSC-8953013 https://reactome.org/PathwayBrowser/#/R-SSC-8953013 E2F7 binds E2F8 IEA Sus scrofa A0A287AUT3 R-SSC-8953037 https://reactome.org/PathwayBrowser/#/R-SSC-8953037 E2F8 forms homodimers IEA Sus scrofa A0A287AUU3 R-SSC-113504 https://reactome.org/PathwayBrowser/#/R-SSC-113504 Detection of damage during initiation of DNA synthesis in S-phase IEA Sus scrofa A0A287AUU3 R-SSC-174425 https://reactome.org/PathwayBrowser/#/R-SSC-174425 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere IEA Sus scrofa A0A287AUU3 R-SSC-174427 https://reactome.org/PathwayBrowser/#/R-SSC-174427 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere IEA Sus scrofa A0A287AUU3 R-SSC-174452 https://reactome.org/PathwayBrowser/#/R-SSC-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere IEA Sus scrofa A0A287AUU3 R-SSC-68913 https://reactome.org/PathwayBrowser/#/R-SSC-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Sus scrofa A0A287AUU3 R-SSC-68914 https://reactome.org/PathwayBrowser/#/R-SSC-68914 DNA polymerase alpha:primase binds at the origin IEA Sus scrofa A0A287AUU3 R-SSC-68950 https://reactome.org/PathwayBrowser/#/R-SSC-68950 The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin IEA Sus scrofa A0A287AUU3 R-SSC-69053 https://reactome.org/PathwayBrowser/#/R-SSC-69053 RFC binding displaces Pol Alpha IEA Sus scrofa A0A287AUU3 R-SSC-69063 https://reactome.org/PathwayBrowser/#/R-SSC-69063 Loading of PCNA - Sliding Clamp Formation IEA Sus scrofa A0A287AUU3 R-SSC-69068 https://reactome.org/PathwayBrowser/#/R-SSC-69068 RFC dissociates after sliding clamp formation IEA Sus scrofa A0A287AUU3 R-SSC-69074 https://reactome.org/PathwayBrowser/#/R-SSC-69074 Formation of Processive Complex IEA Sus scrofa A0A287AUU3 R-SSC-69116 https://reactome.org/PathwayBrowser/#/R-SSC-69116 Formation of Okazaki fragments IEA Sus scrofa A0A287AUU3 R-SSC-69127 https://reactome.org/PathwayBrowser/#/R-SSC-69127 Formation of the Flap Intermediate IEA Sus scrofa A0A287AUU3 R-SSC-69140 https://reactome.org/PathwayBrowser/#/R-SSC-69140 RPA binds to the Flap IEA Sus scrofa A0A287AUU3 R-SSC-69142 https://reactome.org/PathwayBrowser/#/R-SSC-69142 Recruitment of Dna2 endonuclease IEA Sus scrofa A0A287AUU3 R-SSC-69144 https://reactome.org/PathwayBrowser/#/R-SSC-69144 Removal of RNA primer and dissociation of RPA and Dna2 IEA Sus scrofa A0A287AUU3 R-SSC-69152 https://reactome.org/PathwayBrowser/#/R-SSC-69152 Removal of remaining Flap IEA Sus scrofa A0A287AUU3 R-SSC-9668597 https://reactome.org/PathwayBrowser/#/R-SSC-9668597 DNA polymerase:primase binds G-strand of the telomere IEA Sus scrofa A0A287AUX2 R-SSC-110364 https://reactome.org/PathwayBrowser/#/R-SSC-110364 PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 IEA Sus scrofa A0A287AUX2 R-SSC-110368 https://reactome.org/PathwayBrowser/#/R-SSC-110368 POLD,POLE-mediated DNA strand displacement synthesis IEA Sus scrofa A0A287AUX2 R-SSC-110371 https://reactome.org/PathwayBrowser/#/R-SSC-110371 LIG1 binds APEX1 and PCNA at SSB IEA Sus scrofa A0A287AUX2 R-SSC-5651805 https://reactome.org/PathwayBrowser/#/R-SSC-5651805 LIG1 bound to APEX1 and PCNA ligates SSB IEA Sus scrofa A0A287AUX2 R-SSC-5652005 https://reactome.org/PathwayBrowser/#/R-SSC-5652005 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA IEA Sus scrofa A0A287AUX2 R-SSC-5652009 https://reactome.org/PathwayBrowser/#/R-SSC-5652009 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA IEA Sus scrofa A0A287AUX2 R-SSC-5653838 https://reactome.org/PathwayBrowser/#/R-SSC-5653838 POLD,POLE binds deISGylated PCNA after TLS IEA Sus scrofa A0A287AUX2 R-SSC-5690213 https://reactome.org/PathwayBrowser/#/R-SSC-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Sus scrofa A0A287AUX2 R-SSC-5690988 https://reactome.org/PathwayBrowser/#/R-SSC-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Sus scrofa A0A287AUX2 R-SSC-5691001 https://reactome.org/PathwayBrowser/#/R-SSC-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Sus scrofa A0A287AUX2 R-SSC-5693593 https://reactome.org/PathwayBrowser/#/R-SSC-5693593 D-loop extension by DNA polymerases IEA Sus scrofa A0A287AUX2 R-SSC-6782208 https://reactome.org/PathwayBrowser/#/R-SSC-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Sus scrofa A0A287AUX2 R-SSC-6782211 https://reactome.org/PathwayBrowser/#/R-SSC-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Sus scrofa A0A287AUX2 R-SSC-6782224 https://reactome.org/PathwayBrowser/#/R-SSC-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Sus scrofa A0A287AUX2 R-SSC-6782227 https://reactome.org/PathwayBrowser/#/R-SSC-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Sus scrofa A0A287AUX2 R-SSC-68913 https://reactome.org/PathwayBrowser/#/R-SSC-68913 The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin IEA Sus scrofa A0A287AUX2 R-SSC-68914 https://reactome.org/PathwayBrowser/#/R-SSC-68914 DNA polymerase alpha:primase binds at the origin IEA Sus scrofa A0A287AUX2 R-SSC-68960 https://reactome.org/PathwayBrowser/#/R-SSC-68960 DNA polymerase epsilon binds at the origin IEA Sus scrofa A0A287AUX3 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A287AUX3 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa A0A287AUX3 R-SSC-9706287 https://reactome.org/PathwayBrowser/#/R-SSC-9706287 Active FLT3 binds to ABL2 IEA Sus scrofa A0A287AUX7 R-SSC-909718 https://reactome.org/PathwayBrowser/#/R-SSC-909718 Formation of p-STAT1 homodimer IEA Sus scrofa A0A287AUX7 R-SSC-909719 https://reactome.org/PathwayBrowser/#/R-SSC-909719 Recruitment of STAT2 to p-IFNAR1 IEA Sus scrofa A0A287AUX7 R-SSC-909720 https://reactome.org/PathwayBrowser/#/R-SSC-909720 IFN alpha/beta binds to IFNAR2 IEA Sus scrofa A0A287AUX7 R-SSC-909722 https://reactome.org/PathwayBrowser/#/R-SSC-909722 Release of p-STAT2:p-STAT1 dimer IEA Sus scrofa A0A287AUX7 R-SSC-909724 https://reactome.org/PathwayBrowser/#/R-SSC-909724 Recruitment of IFNAR1 IEA Sus scrofa A0A287AUX7 R-SSC-909729 https://reactome.org/PathwayBrowser/#/R-SSC-909729 Activation of JAK kinases IEA Sus scrofa A0A287AUX7 R-SSC-909730 https://reactome.org/PathwayBrowser/#/R-SSC-909730 Phosphorylation of INFAR1 by TYK2 IEA Sus scrofa A0A287AUX7 R-SSC-909732 https://reactome.org/PathwayBrowser/#/R-SSC-909732 Phosphorylation of STAT2 IEA Sus scrofa A0A287AUX7 R-SSC-997309 https://reactome.org/PathwayBrowser/#/R-SSC-997309 Dephosphorylation of STAT1 by SHP2 IEA Sus scrofa A0A287AUX7 R-SSC-997311 https://reactome.org/PathwayBrowser/#/R-SSC-997311 Dephosphorylation of TYK2 by PTP1B IEA Sus scrofa A0A287AUX7 R-SSC-997314 https://reactome.org/PathwayBrowser/#/R-SSC-997314 Dephosphorylation of JAK1 by SHP1 IEA Sus scrofa A0A287AUX9 R-SSC-5696365 https://reactome.org/PathwayBrowser/#/R-SSC-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe, MeOH IEA Sus scrofa A0A287AUZ1 R-SSC-5694485 https://reactome.org/PathwayBrowser/#/R-SSC-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Sus scrofa A0A287AV01 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa A0A287AV01 R-SSC-3928651 https://reactome.org/PathwayBrowser/#/R-SSC-3928651 NGEF exchanges GTP for GDP on RHOA IEA Sus scrofa A0A287AV01 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa A0A287AV01 R-SSC-8980691 https://reactome.org/PathwayBrowser/#/R-SSC-8980691 RHOA GEFs activate RHOA IEA Sus scrofa A0A287AV01 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A287AV01 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa A0A287AV02 R-SSC-3108203 https://reactome.org/PathwayBrowser/#/R-SSC-3108203 PRC1 SUMOylates CTBP1 with SUMO2,3 IEA Sus scrofa A0A287AV02 R-SSC-3108209 https://reactome.org/PathwayBrowser/#/R-SSC-3108209 PRC1 SUMOylates CTBP1 with SUMO1 IEA Sus scrofa A0A287AV02 R-SSC-3229089 https://reactome.org/PathwayBrowser/#/R-SSC-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Sus scrofa A0A287AV02 R-SSC-3229102 https://reactome.org/PathwayBrowser/#/R-SSC-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Sus scrofa A0A287AV02 R-SSC-3927824 https://reactome.org/PathwayBrowser/#/R-SSC-3927824 PRC1 SUMOylates CASP8AP2 with SUMO1 IEA Sus scrofa A0A287AV02 R-SSC-4551655 https://reactome.org/PathwayBrowser/#/R-SSC-4551655 CBX4 SUMOylates BMI1 in PRC1 with SUMO1 IEA Sus scrofa A0A287AV02 R-SSC-4551727 https://reactome.org/PathwayBrowser/#/R-SSC-4551727 CBX4 SUMOylates CBX4 in PRC1 with SUMO1 IEA Sus scrofa A0A287AV02 R-SSC-4570463 https://reactome.org/PathwayBrowser/#/R-SSC-4570463 CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 IEA Sus scrofa A0A287AV02 R-SSC-4570499 https://reactome.org/PathwayBrowser/#/R-SSC-4570499 CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 IEA Sus scrofa A0A287AV02 R-SSC-8937989 https://reactome.org/PathwayBrowser/#/R-SSC-8937989 RUNX1 binds PRC1 complexes IEA Sus scrofa A0A287AV02 R-SSC-8943817 https://reactome.org/PathwayBrowser/#/R-SSC-8943817 MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter IEA Sus scrofa A0A287AV02 R-SSC-8954082 https://reactome.org/PathwayBrowser/#/R-SSC-8954082 E2F6 binds the PRC1 complex IEA Sus scrofa A0A287AV04 R-SSC-389821 https://reactome.org/PathwayBrowser/#/R-SSC-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Sus scrofa A0A287AV04 R-SSC-9033235 https://reactome.org/PathwayBrowser/#/R-SSC-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A287AV04 R-SSC-9033236 https://reactome.org/PathwayBrowser/#/R-SSC-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Sus scrofa A0A287AV07 R-SSC-8848215 https://reactome.org/PathwayBrowser/#/R-SSC-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Sus scrofa A0A287AV13 R-SSC-8981637 https://reactome.org/PathwayBrowser/#/R-SSC-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Sus scrofa A0A287AV13 R-SSC-9013022 https://reactome.org/PathwayBrowser/#/R-SSC-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Sus scrofa A0A287AV13 R-SSC-9018794 https://reactome.org/PathwayBrowser/#/R-SSC-9018794 RHOV binds effectors at the plasma membrane IEA Sus scrofa A0A287AV14 R-SSC-1955380 https://reactome.org/PathwayBrowser/#/R-SSC-1955380 TIMM9:TIMM10 transfers proteins to TIMM22 IEA Sus scrofa A0A287AV19 R-SSC-8982012 https://reactome.org/PathwayBrowser/#/R-SSC-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Sus scrofa A0A287AV19 R-SSC-8982017 https://reactome.org/PathwayBrowser/#/R-SSC-8982017 Active G alpha (q) binds RGS proteins IEA Sus scrofa A0A287AV19 R-SSC-8982019 https://reactome.org/PathwayBrowser/#/R-SSC-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Sus scrofa A0A287AV19 R-SSC-8982020 https://reactome.org/PathwayBrowser/#/R-SSC-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Sus scrofa A0A287AV19 R-SSC-8982025 https://reactome.org/PathwayBrowser/#/R-SSC-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Sus scrofa A0A287AV19 R-SSC-8982026 https://reactome.org/PathwayBrowser/#/R-SSC-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Sus scrofa A0A287AV22 R-SSC-9013144 https://reactome.org/PathwayBrowser/#/R-SSC-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Sus scrofa A0A287AV22 R-SSC-9013437 https://reactome.org/PathwayBrowser/#/R-SSC-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Sus scrofa A0A287AV22 R-SSC-9018794 https://reactome.org/PathwayBrowser/#/R-SSC-9018794 RHOV binds effectors at the plasma membrane IEA Sus scrofa A0A287AV22 R-SSC-9693282 https://reactome.org/PathwayBrowser/#/R-SSC-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Sus scrofa A0A287AV32 R-SSC-373813 https://reactome.org/PathwayBrowser/#/R-SSC-373813 Receptor CXCR2 binds ligands CXCL1 to 7 IEA Sus scrofa A0A287AV32 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287AV32 R-SSC-6798745 https://reactome.org/PathwayBrowser/#/R-SSC-6798745 Exocytosis of tertiary granule lumen proteins IEA Sus scrofa A0A287AV32 R-SSC-6798749 https://reactome.org/PathwayBrowser/#/R-SSC-6798749 Exocytosis of specific granule lumen proteins IEA Sus scrofa A0A287AV32 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287AV32 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287AV35 R-SSC-5250930 https://reactome.org/PathwayBrowser/#/R-SSC-5250930 B-WICH recruits histone acetyltransferases IEA Sus scrofa A0A287AV35 R-SSC-5250938 https://reactome.org/PathwayBrowser/#/R-SSC-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Sus scrofa A0A287AV35 R-SSC-75079 https://reactome.org/PathwayBrowser/#/R-SSC-75079 Formation of AT-AC C complex IEA Sus scrofa A0A287AV35 R-SSC-75081 https://reactome.org/PathwayBrowser/#/R-SSC-75081 Formation of AT-AC B Complex IEA Sus scrofa A0A287AV35 R-SSC-75082 https://reactome.org/PathwayBrowser/#/R-SSC-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Sus scrofa A0A287AV35 R-SSC-75083 https://reactome.org/PathwayBrowser/#/R-SSC-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Sus scrofa A0A287AV35 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287AV37 R-SSC-6783880 https://reactome.org/PathwayBrowser/#/R-SSC-6783880 PIPOX oxidises PPCA to P6C IEA Sus scrofa A0A287AV37 R-SSC-9033235 https://reactome.org/PathwayBrowser/#/R-SSC-9033235 Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix IEA Sus scrofa A0A287AV37 R-SSC-9033236 https://reactome.org/PathwayBrowser/#/R-SSC-9033236 PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) IEA Sus scrofa A0A287AV43 R-SSC-159101 https://reactome.org/PathwayBrowser/#/R-SSC-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Sus scrofa A0A287AV43 R-SSC-72180 https://reactome.org/PathwayBrowser/#/R-SSC-72180 Cleavage of mRNA at the 3'-end IEA Sus scrofa A0A287AV43 R-SSC-72185 https://reactome.org/PathwayBrowser/#/R-SSC-72185 mRNA polyadenylation IEA Sus scrofa A0A287AV43 R-SSC-8849157 https://reactome.org/PathwayBrowser/#/R-SSC-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Sus scrofa A0A287AV47 R-SSC-159101 https://reactome.org/PathwayBrowser/#/R-SSC-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) IEA Sus scrofa A0A287AV47 R-SSC-72180 https://reactome.org/PathwayBrowser/#/R-SSC-72180 Cleavage of mRNA at the 3'-end IEA Sus scrofa A0A287AV47 R-SSC-72185 https://reactome.org/PathwayBrowser/#/R-SSC-72185 mRNA polyadenylation IEA Sus scrofa A0A287AV47 R-SSC-75097 https://reactome.org/PathwayBrowser/#/R-SSC-75097 Transport of the export-competent mRNP complex through the NPC IEA Sus scrofa A0A287AV47 R-SSC-75098 https://reactome.org/PathwayBrowser/#/R-SSC-75098 mRNP complex dissociates from cytosolic face of NPC IEA Sus scrofa A0A287AV47 R-SSC-8849157 https://reactome.org/PathwayBrowser/#/R-SSC-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally IEA Sus scrofa A0A287AV47 R-SSC-9018778 https://reactome.org/PathwayBrowser/#/R-SSC-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Sus scrofa A0A287AV47 R-SSC-9018787 https://reactome.org/PathwayBrowser/#/R-SSC-9018787 RHOBTB2 binds interacting proteins at the endosome membrane IEA Sus scrofa A0A287AV47 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A287AV47 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287AV47 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A287AV47 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A287AV56 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa A0A287AV56 R-SSC-398184 https://reactome.org/PathwayBrowser/#/R-SSC-398184 LARG activation by G alpha 12/13 IEA Sus scrofa A0A287AV56 R-SSC-398185 https://reactome.org/PathwayBrowser/#/R-SSC-398185 LARG binds plexin B1 IEA Sus scrofa A0A287AV56 R-SSC-416588 https://reactome.org/PathwayBrowser/#/R-SSC-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Sus scrofa A0A287AV56 R-SSC-416594 https://reactome.org/PathwayBrowser/#/R-SSC-416594 LARG and PDZ-RhoGEF binds to Plexin-B1 IEA Sus scrofa A0A287AV56 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa A0A287AV56 R-SSC-8980691 https://reactome.org/PathwayBrowser/#/R-SSC-8980691 RHOA GEFs activate RHOA IEA Sus scrofa A0A287AV56 R-SSC-9013023 https://reactome.org/PathwayBrowser/#/R-SSC-9013023 RHOB GEFs activate RHOB IEA Sus scrofa A0A287AV56 R-SSC-9013109 https://reactome.org/PathwayBrowser/#/R-SSC-9013109 RHOC GEFs activate RHOC IEA Sus scrofa A0A287AV56 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa A0A287AV68 R-SSC-392054 https://reactome.org/PathwayBrowser/#/R-SSC-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Sus scrofa A0A287AV68 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287AV76 R-SSC-5252079 https://reactome.org/PathwayBrowser/#/R-SSC-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP IEA Sus scrofa A0A287AV88 R-SSC-1602368 https://reactome.org/PathwayBrowser/#/R-SSC-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Sus scrofa A0A287AV88 R-SSC-1602374 https://reactome.org/PathwayBrowser/#/R-SSC-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Sus scrofa A0A287AV88 R-SSC-1602377 https://reactome.org/PathwayBrowser/#/R-SSC-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Sus scrofa A0A287AV88 R-SSC-1602398 https://reactome.org/PathwayBrowser/#/R-SSC-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Sus scrofa A0A287AV88 R-SSC-1602417 https://reactome.org/PathwayBrowser/#/R-SSC-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Sus scrofa A0A287AV88 R-SSC-1602446 https://reactome.org/PathwayBrowser/#/R-SSC-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Sus scrofa A0A287AVA3 R-SSC-8877612 https://reactome.org/PathwayBrowser/#/R-SSC-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Sus scrofa A0A287AVA3 R-SSC-8933452 https://reactome.org/PathwayBrowser/#/R-SSC-8933452 YWHAE dimer binds phosphorylated DENND1 proteins IEA Sus scrofa A0A287AVA7 R-SSC-429860 https://reactome.org/PathwayBrowser/#/R-SSC-429860 DCP1-DCP2 complex decaps mRNA IEA Sus scrofa A0A287AVA7 R-SSC-429978 https://reactome.org/PathwayBrowser/#/R-SSC-429978 Lsm1-7 Complex binds deadenylated mRNA IEA Sus scrofa A0A287AVB1 R-SSC-190682 https://reactome.org/PathwayBrowser/#/R-SSC-190682 Connexin synthesis (generic) IEA Sus scrofa A0A287AVB5 R-SSC-1971482 https://reactome.org/PathwayBrowser/#/R-SSC-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin IEA Sus scrofa A0A287AVC8 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AVD1 R-SSC-9861563 https://reactome.org/PathwayBrowser/#/R-SSC-9861563 CTLH E3 ligase ubiquitinates LDHA IEA Sus scrofa A0A287AVD1 R-SSC-9861640 https://reactome.org/PathwayBrowser/#/R-SSC-9861640 CTLH E3 ligase ubiquitinates PKM-1 IEA Sus scrofa A0A287AVG7 R-SSC-8957389 https://reactome.org/PathwayBrowser/#/R-SSC-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Sus scrofa A0A287AVI7 R-SSC-1011576 https://reactome.org/PathwayBrowser/#/R-SSC-1011576 EHD proteins interact with Rabenosyn-5 IEA Sus scrofa A0A287AVI7 R-SSC-1011600 https://reactome.org/PathwayBrowser/#/R-SSC-1011600 Rabenosyn-5 connects Rab5 to VPS-45 IEA Sus scrofa A0A287AVI7 R-SSC-188002 https://reactome.org/PathwayBrowser/#/R-SSC-188002 Rab5-mediated recruitment of class III PI3K to TLR9 IEA Sus scrofa A0A287AVK8 R-SSC-139855 https://reactome.org/PathwayBrowser/#/R-SSC-139855 P2X1-mediated entry of Ca++ from plasma IEA Sus scrofa A0A287AVK8 R-SSC-419490 https://reactome.org/PathwayBrowser/#/R-SSC-419490 Binding of ATP to P2X receptors IEA Sus scrofa A0A287AVM4 R-SSC-5658231 https://reactome.org/PathwayBrowser/#/R-SSC-5658231 RAS GAPs stimulate RAS GTPase activity IEA Sus scrofa A0A287AVM4 R-SSC-5658424 https://reactome.org/PathwayBrowser/#/R-SSC-5658424 KBTBD7:CUL3:RBX1 ubiquitinates NF1 IEA Sus scrofa A0A287AVM4 R-SSC-5658430 https://reactome.org/PathwayBrowser/#/R-SSC-5658430 NF1 is degraded by the proteasome IEA Sus scrofa A0A287AVM4 R-SSC-5658435 https://reactome.org/PathwayBrowser/#/R-SSC-5658435 RAS GAPs bind RAS:GTP IEA Sus scrofa A0A287AVM4 R-SSC-5658438 https://reactome.org/PathwayBrowser/#/R-SSC-5658438 SPRED dimer binds NF1 IEA Sus scrofa A0A287AVN0 R-SSC-1855154 https://reactome.org/PathwayBrowser/#/R-SSC-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa A0A287AVN0 R-SSC-1855210 https://reactome.org/PathwayBrowser/#/R-SSC-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa A0A287AVN0 R-SSC-1855211 https://reactome.org/PathwayBrowser/#/R-SSC-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa A0A287AVP0 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A287AVP0 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A287AVP0 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287AVP0 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287AVP0 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287AVP0 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287AVP0 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287AVP0 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287AVP0 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287AVP0 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287AVP0 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287AVR0 R-SSC-156808 https://reactome.org/PathwayBrowser/#/R-SSC-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Sus scrofa A0A287AVR0 R-SSC-156823 https://reactome.org/PathwayBrowser/#/R-SSC-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Sus scrofa A0A287AVR0 R-SSC-157849 https://reactome.org/PathwayBrowser/#/R-SSC-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Sus scrofa A0A287AVR0 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa A0A287AVR0 R-SSC-72676 https://reactome.org/PathwayBrowser/#/R-SSC-72676 eIF3 and eIF1A bind to the 40S subunit IEA Sus scrofa A0A287AVR0 R-SSC-72691 https://reactome.org/PathwayBrowser/#/R-SSC-72691 Formation of the 43S pre-initiation complex IEA Sus scrofa A0A287AVR0 R-SSC-72697 https://reactome.org/PathwayBrowser/#/R-SSC-72697 Start codon recognition IEA Sus scrofa A0A287AVR3 R-SSC-1168633 https://reactome.org/PathwayBrowser/#/R-SSC-1168633 NF-kappaB translocates from the cytosol to the nucleus IEA Sus scrofa A0A287AVR3 R-SSC-1168638 https://reactome.org/PathwayBrowser/#/R-SSC-1168638 Activated IKK phosphorylates I-kappaB IEA Sus scrofa A0A287AVR3 R-SSC-1168640 https://reactome.org/PathwayBrowser/#/R-SSC-1168640 Ubiquitinated IkB is degraded IEA Sus scrofa A0A287AVR3 R-SSC-168140 https://reactome.org/PathwayBrowser/#/R-SSC-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor IEA Sus scrofa A0A287AVR3 R-SSC-168166 https://reactome.org/PathwayBrowser/#/R-SSC-168166 NF-kappa-B complex is transported from cytosol to nucleus IEA Sus scrofa A0A287AVR3 R-SSC-193691 https://reactome.org/PathwayBrowser/#/R-SSC-193691 NF-kB migrates to the nucleus and turns on transcription IEA Sus scrofa A0A287AVR3 R-SSC-193700 https://reactome.org/PathwayBrowser/#/R-SSC-193700 p75NTR ICD signals to NF-kB IEA Sus scrofa A0A287AVR3 R-SSC-193705 https://reactome.org/PathwayBrowser/#/R-SSC-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate IEA Sus scrofa A0A287AVR3 R-SSC-202541 https://reactome.org/PathwayBrowser/#/R-SSC-202541 p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB IEA Sus scrofa A0A287AVR3 R-SSC-209061 https://reactome.org/PathwayBrowser/#/R-SSC-209061 Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex IEA Sus scrofa A0A287AVR3 R-SSC-209063 https://reactome.org/PathwayBrowser/#/R-SSC-209063 Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex IEA Sus scrofa A0A287AVR3 R-SSC-209125 https://reactome.org/PathwayBrowser/#/R-SSC-209125 SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex IEA Sus scrofa A0A287AVR3 R-SSC-2730894 https://reactome.org/PathwayBrowser/#/R-SSC-2730894 NFKB1:RELA translocates from the cytosol to the nucleus IEA Sus scrofa A0A287AVR3 R-SSC-448703 https://reactome.org/PathwayBrowser/#/R-SSC-448703 Interleukin-1 family precursors are cleaved by caspase-1 IEA Sus scrofa A0A287AVR3 R-SSC-451634 https://reactome.org/PathwayBrowser/#/R-SSC-451634 NFKB p105, TPL2 (COT) and ABIN2 form a stable complex IEA Sus scrofa A0A287AVR3 R-SSC-5607724 https://reactome.org/PathwayBrowser/#/R-SSC-5607724 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex IEA Sus scrofa A0A287AVR3 R-SSC-5624473 https://reactome.org/PathwayBrowser/#/R-SSC-5624473 Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit IEA Sus scrofa A0A287AVR3 R-SSC-5660660 https://reactome.org/PathwayBrowser/#/R-SSC-5660660 p300 acetylates RELA subunit IEA Sus scrofa A0A287AVR3 R-SSC-5660666 https://reactome.org/PathwayBrowser/#/R-SSC-5660666 CBP and p300 binds NF-kB complex IEA Sus scrofa A0A287AVR3 R-SSC-5684261 https://reactome.org/PathwayBrowser/#/R-SSC-5684261 MAP3K8 is phosphorylated IEA Sus scrofa A0A287AVR3 R-SSC-5684267 https://reactome.org/PathwayBrowser/#/R-SSC-5684267 IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex IEA Sus scrofa A0A287AVR3 R-SSC-5684273 https://reactome.org/PathwayBrowser/#/R-SSC-5684273 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 IEA Sus scrofa A0A287AVR3 R-SSC-5684275 https://reactome.org/PathwayBrowser/#/R-SSC-5684275 IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 IEA Sus scrofa A0A287AVR3 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A287AVR3 R-SSC-6798749 https://reactome.org/PathwayBrowser/#/R-SSC-6798749 Exocytosis of specific granule lumen proteins IEA Sus scrofa A0A287AVR3 R-SSC-8865237 https://reactome.org/PathwayBrowser/#/R-SSC-8865237 SETD6 methylates RELA in the NFkB complex IEA Sus scrofa A0A287AVR3 R-SSC-9604480 https://reactome.org/PathwayBrowser/#/R-SSC-9604480 NFkB complex translocates from the cytosol to the nucleus IEA Sus scrofa A0A287AVR3 R-SSC-9630923 https://reactome.org/PathwayBrowser/#/R-SSC-9630923 NF-kappa-B inhibitor binds NF-kappa-B complex IEA Sus scrofa A0A287AVR3 R-SSC-9773803 https://reactome.org/PathwayBrowser/#/R-SSC-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor IEA Sus scrofa A0A287AVR3 R-SSC-9861486 https://reactome.org/PathwayBrowser/#/R-SSC-9861486 PTK2 (FAK) and Gq/11 enhance the degradation of NFKBIA (IkBalpha), phosphorylation of RELA (p65) on serine-536, and translocation of p-S536-RELA:NFKB1 (p65:p50) to the nucleus IEA Sus scrofa A0A287AVR4 R-SSC-209823 https://reactome.org/PathwayBrowser/#/R-SSC-209823 Tyrosine is hydroxylated to dopa IEA Sus scrofa A0A287AVR8 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AVS9 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A287AVS9 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A287AVS9 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A287AVS9 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A287AVS9 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A287AVT1 R-SSC-209821 https://reactome.org/PathwayBrowser/#/R-SSC-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Sus scrofa A0A287AVT4 R-SSC-212222 https://reactome.org/PathwayBrowser/#/R-SSC-212222 PRC2 recruits DNA methyltransferases IEA Sus scrofa A0A287AVT4 R-SSC-212252 https://reactome.org/PathwayBrowser/#/R-SSC-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Sus scrofa A0A287AVT4 R-SSC-212263 https://reactome.org/PathwayBrowser/#/R-SSC-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Sus scrofa A0A287AVT4 R-SSC-212269 https://reactome.org/PathwayBrowser/#/R-SSC-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Sus scrofa A0A287AVT4 R-SSC-3240295 https://reactome.org/PathwayBrowser/#/R-SSC-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Sus scrofa A0A287AVT4 R-SSC-3240957 https://reactome.org/PathwayBrowser/#/R-SSC-3240957 Formation of PRC2-EZH2 complex IEA Sus scrofa A0A287AVT4 R-SSC-5638332 https://reactome.org/PathwayBrowser/#/R-SSC-5638332 PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) IEA Sus scrofa A0A287AVT4 R-SSC-8943817 https://reactome.org/PathwayBrowser/#/R-SSC-8943817 MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter IEA Sus scrofa A0A287AVT4 R-SSC-8954110 https://reactome.org/PathwayBrowser/#/R-SSC-8954110 E2F6:TFDP1:EPC1 binds the PRC2 complex IEA Sus scrofa A0A287AVV3 R-SSC-2029465 https://reactome.org/PathwayBrowser/#/R-SSC-2029465 RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) IEA Sus scrofa A0A287AVV3 R-SSC-2029466 https://reactome.org/PathwayBrowser/#/R-SSC-2029466 (WASPs, WAVE):G-actin:ARP2/3 binds F-actin IEA Sus scrofa A0A287AVV3 R-SSC-2029469 https://reactome.org/PathwayBrowser/#/R-SSC-2029469 p-ERK phosphorylates WAVEs and ABI IEA Sus scrofa A0A287AVV3 R-SSC-2130194 https://reactome.org/PathwayBrowser/#/R-SSC-2130194 ABL phosphorylates WAVEs IEA Sus scrofa A0A287AVV3 R-SSC-2197690 https://reactome.org/PathwayBrowser/#/R-SSC-2197690 Detachment of WASP/WAVE IEA Sus scrofa A0A287AVV3 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A287AVV4 R-SSC-432067 https://reactome.org/PathwayBrowser/#/R-SSC-432067 Aquaporin-4 passively transports water out of cell IEA Sus scrofa A0A287AVV4 R-SSC-507868 https://reactome.org/PathwayBrowser/#/R-SSC-507868 Aquaporins passively transport water into cells IEA Sus scrofa A0A287AVV4 R-SSC-507870 https://reactome.org/PathwayBrowser/#/R-SSC-507870 Aquaporins passively transport water out of cells IEA Sus scrofa A0A287AVV9 R-SSC-5173005 https://reactome.org/PathwayBrowser/#/R-SSC-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Sus scrofa A0A287AVV9 R-SSC-5173192 https://reactome.org/PathwayBrowser/#/R-SSC-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Sus scrofa A0A287AVW4 R-SSC-9018815 https://reactome.org/PathwayBrowser/#/R-SSC-9018815 RHOT1 binds effectors at the mitochondrial outer membrane IEA Sus scrofa A0A287AVW4 R-SSC-9018824 https://reactome.org/PathwayBrowser/#/R-SSC-9018824 RHOT2 binds effectors at the mitochondrial outer membrane IEA Sus scrofa A0A287AVY9 R-SSC-1011598 https://reactome.org/PathwayBrowser/#/R-SSC-1011598 DOCKs bind to RhoGEFs IEA Sus scrofa A0A287AVY9 R-SSC-9013143 https://reactome.org/PathwayBrowser/#/R-SSC-9013143 RAC1 GEFs activate RAC1 IEA Sus scrofa A0A287AVY9 R-SSC-9013159 https://reactome.org/PathwayBrowser/#/R-SSC-9013159 CDC42 GEFs activate CDC42 IEA Sus scrofa A0A287AVZ0 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287AVZ1 R-SSC-191972 https://reactome.org/PathwayBrowser/#/R-SSC-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Sus scrofa A0A287AVZ1 R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa A0A287AVZ1 R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa A0A287AVZ1 R-SSC-194187 https://reactome.org/PathwayBrowser/#/R-SSC-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Sus scrofa A0A287AVZ1 R-SSC-4085296 https://reactome.org/PathwayBrowser/#/R-SSC-4085296 SUMOylation of NCOA1 with SUMO1 IEA Sus scrofa A0A287AVZ1 R-SSC-5340251 https://reactome.org/PathwayBrowser/#/R-SSC-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Sus scrofa A0A287AVZ1 R-SSC-5579018 https://reactome.org/PathwayBrowser/#/R-SSC-5579018 NCOA1(868-1441) binds PAX3(1-319) IEA Sus scrofa A0A287AVZ1 R-SSC-9008270 https://reactome.org/PathwayBrowser/#/R-SSC-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Sus scrofa A0A287AVZ1 R-SSC-9023840 https://reactome.org/PathwayBrowser/#/R-SSC-9023840 HATs and coactivators are recruited to the CTSD gene IEA Sus scrofa A0A287AVZ1 R-SSC-9023860 https://reactome.org/PathwayBrowser/#/R-SSC-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Sus scrofa A0A287AVZ1 R-SSC-9023884 https://reactome.org/PathwayBrowser/#/R-SSC-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Sus scrofa A0A287AVZ1 R-SSC-9029551 https://reactome.org/PathwayBrowser/#/R-SSC-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Sus scrofa A0A287AVZ1 R-SSC-9029561 https://reactome.org/PathwayBrowser/#/R-SSC-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Sus scrofa A0A287AVZ1 R-SSC-9029580 https://reactome.org/PathwayBrowser/#/R-SSC-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Sus scrofa A0A287AVZ1 R-SSC-9843120 https://reactome.org/PathwayBrowser/#/R-SSC-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Sus scrofa A0A287AVZ6 R-SSC-83803 https://reactome.org/PathwayBrowser/#/R-SSC-83803 Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex IEA Sus scrofa A0A287AW04 R-SSC-1602368 https://reactome.org/PathwayBrowser/#/R-SSC-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Sus scrofa A0A287AW04 R-SSC-1602374 https://reactome.org/PathwayBrowser/#/R-SSC-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Sus scrofa A0A287AW04 R-SSC-1602377 https://reactome.org/PathwayBrowser/#/R-SSC-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Sus scrofa A0A287AW04 R-SSC-1602398 https://reactome.org/PathwayBrowser/#/R-SSC-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Sus scrofa A0A287AW04 R-SSC-1602417 https://reactome.org/PathwayBrowser/#/R-SSC-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Sus scrofa A0A287AW04 R-SSC-1602446 https://reactome.org/PathwayBrowser/#/R-SSC-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Sus scrofa A0A287AW11 R-SSC-8940388 https://reactome.org/PathwayBrowser/#/R-SSC-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Sus scrofa A0A287AW22 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa A0A287AW32 R-SSC-72103 https://reactome.org/PathwayBrowser/#/R-SSC-72103 Formation of pre-mRNPs IEA Sus scrofa A0A287AW32 R-SSC-9770119 https://reactome.org/PathwayBrowser/#/R-SSC-9770119 Formation of the Spliceosomal E complex IEA Sus scrofa A0A287AW32 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A287AW32 R-SSC-9770145 https://reactome.org/PathwayBrowser/#/R-SSC-9770145 Formation of the Spliceosomal Bact complex IEA Sus scrofa A0A287AW32 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A287AW32 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A287AW36 R-SSC-975926 https://reactome.org/PathwayBrowser/#/R-SSC-975926 Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 IEA Sus scrofa A0A287AW37 R-SSC-5205798 https://reactome.org/PathwayBrowser/#/R-SSC-5205798 PRMT1,PRMT6 methylate arginine-4 of histone H4 IEA Sus scrofa A0A287AW37 R-SSC-5205820 https://reactome.org/PathwayBrowser/#/R-SSC-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Sus scrofa A0A287AW37 R-SSC-5205824 https://reactome.org/PathwayBrowser/#/R-SSC-5205824 CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) IEA Sus scrofa A0A287AW37 R-SSC-5229203 https://reactome.org/PathwayBrowser/#/R-SSC-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Sus scrofa A0A287AW37 R-SSC-5661126 https://reactome.org/PathwayBrowser/#/R-SSC-5661126 PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 IEA Sus scrofa A0A287AW37 R-SSC-8935732 https://reactome.org/PathwayBrowser/#/R-SSC-8935732 RUNX1 binds SIN3A,(SIN3B) co-repressor IEA Sus scrofa A0A287AW37 R-SSC-8936584 https://reactome.org/PathwayBrowser/#/R-SSC-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Sus scrofa A0A287AW37 R-SSC-8936608 https://reactome.org/PathwayBrowser/#/R-SSC-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Sus scrofa A0A287AW37 R-SSC-8937022 https://reactome.org/PathwayBrowser/#/R-SSC-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Sus scrofa A0A287AW37 R-SSC-8937113 https://reactome.org/PathwayBrowser/#/R-SSC-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Sus scrofa A0A287AW81 R-SSC-430096 https://reactome.org/PathwayBrowser/#/R-SSC-430096 GP1b-IX-V binds filamin IEA Sus scrofa A0A287AW81 R-SSC-430347 https://reactome.org/PathwayBrowser/#/R-SSC-430347 MigFilin associates with Filamin and F-actin IEA Sus scrofa A0A287AW81 R-SSC-482772 https://reactome.org/PathwayBrowser/#/R-SSC-482772 Release of platelet cytosolic components IEA Sus scrofa A0A287AW81 R-SSC-5669240 https://reactome.org/PathwayBrowser/#/R-SSC-5669240 FLNA binds PAK1 IEA Sus scrofa A0A287AW81 R-SSC-5669250 https://reactome.org/PathwayBrowser/#/R-SSC-5669250 PAK1 phosphorylates FLNA IEA Sus scrofa A0A287AW87 R-SSC-8852127 https://reactome.org/PathwayBrowser/#/R-SSC-8852127 UBA6 conjugates ubiquitin to cytosolic E2 enzymes IEA Sus scrofa A0A287AW87 R-SSC-8852129 https://reactome.org/PathwayBrowser/#/R-SSC-8852129 UBA1 conjugates ubiquitin to cytosolic E2 enzymes IEA Sus scrofa A0A287AW87 R-SSC-8852130 https://reactome.org/PathwayBrowser/#/R-SSC-8852130 UBA1 conjugates ubiquitin to nuclear E2 enzymes IEA Sus scrofa A0A287AW87 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AW87 R-SSC-983152 https://reactome.org/PathwayBrowser/#/R-SSC-983152 Transfer of ubiquitin from E1 to E2 IEA Sus scrofa A0A287AW87 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AW87 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AW90 R-SSC-1013012 https://reactome.org/PathwayBrowser/#/R-SSC-1013012 Binding of Gbeta/gamma to GIRK/Kir3 channels IEA Sus scrofa A0A287AW90 R-SSC-1013013 https://reactome.org/PathwayBrowser/#/R-SSC-1013013 Association of GABA B receptor with G protein beta-gamma subunits IEA Sus scrofa A0A287AW90 R-SSC-1013020 https://reactome.org/PathwayBrowser/#/R-SSC-1013020 Activation of GIRK/Kir3 Channels IEA Sus scrofa A0A287AW90 R-SSC-112271 https://reactome.org/PathwayBrowser/#/R-SSC-112271 The receptor:G-protein complex dissociates IEA Sus scrofa A0A287AW90 R-SSC-114552 https://reactome.org/PathwayBrowser/#/R-SSC-114552 Thrombin-activated PARs activate G12/13 IEA Sus scrofa A0A287AW90 R-SSC-114558 https://reactome.org/PathwayBrowser/#/R-SSC-114558 Thrombin-activated PARs activate Gq IEA Sus scrofa A0A287AW90 R-SSC-167408 https://reactome.org/PathwayBrowser/#/R-SSC-167408 The high affinity receptor complex binds to G-protein IEA Sus scrofa A0A287AW90 R-SSC-167419 https://reactome.org/PathwayBrowser/#/R-SSC-167419 The receptor:G-protein complex releases GDP IEA Sus scrofa A0A287AW90 R-SSC-167429 https://reactome.org/PathwayBrowser/#/R-SSC-167429 The receptor:G-protein complex binds GTP IEA Sus scrofa A0A287AW90 R-SSC-167433 https://reactome.org/PathwayBrowser/#/R-SSC-167433 G-protein beta-gamma subunits rebind the alpha-GDP subunit IEA Sus scrofa A0A287AW90 R-SSC-2485182 https://reactome.org/PathwayBrowser/#/R-SSC-2485182 Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1 IEA Sus scrofa A0A287AW90 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa A0A287AW90 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287AW90 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287AW90 R-SSC-381612 https://reactome.org/PathwayBrowser/#/R-SSC-381612 GLP1R binds GLP1 IEA Sus scrofa A0A287AW90 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa A0A287AW90 R-SSC-392187 https://reactome.org/PathwayBrowser/#/R-SSC-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Sus scrofa A0A287AW90 R-SSC-392195 https://reactome.org/PathwayBrowser/#/R-SSC-392195 Gi activation by P2Y purinoceptor 12 IEA Sus scrofa A0A287AW90 R-SSC-392202 https://reactome.org/PathwayBrowser/#/R-SSC-392202 Dissociation of the P2Y purinoceptor 12:Gi complex IEA Sus scrofa A0A287AW90 R-SSC-392295 https://reactome.org/PathwayBrowser/#/R-SSC-392295 Gbeta:gamma recruits PI3K gamma IEA Sus scrofa A0A287AW90 R-SSC-392300 https://reactome.org/PathwayBrowser/#/R-SSC-392300 G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 IEA Sus scrofa A0A287AW90 R-SSC-392870 https://reactome.org/PathwayBrowser/#/R-SSC-392870 Gs activation by prostacyclin receptor IEA Sus scrofa A0A287AW90 R-SSC-3965444 https://reactome.org/PathwayBrowser/#/R-SSC-3965444 WNT:FZD complex promotes G-protein nucleotide exchange IEA Sus scrofa A0A287AW90 R-SSC-3965447 https://reactome.org/PathwayBrowser/#/R-SSC-3965447 G-protein subunits dissociate from WNT:FZD complex IEA Sus scrofa A0A287AW90 R-SSC-396996 https://reactome.org/PathwayBrowser/#/R-SSC-396996 Thrombin-activated PARs binds G-protein Gq IEA Sus scrofa A0A287AW90 R-SSC-397835 https://reactome.org/PathwayBrowser/#/R-SSC-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Sus scrofa A0A287AW90 R-SSC-397891 https://reactome.org/PathwayBrowser/#/R-SSC-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Sus scrofa A0A287AW90 R-SSC-398040 https://reactome.org/PathwayBrowser/#/R-SSC-398040 Gbeta:gamma activation of PLC beta IEA Sus scrofa A0A287AW90 R-SSC-398193 https://reactome.org/PathwayBrowser/#/R-SSC-398193 PLC beta-mediated PIP2 hydrolysis IEA Sus scrofa A0A287AW90 R-SSC-400037 https://reactome.org/PathwayBrowser/#/R-SSC-400037 Gi,Go Heterotrimeric G-protein complex dissociates IEA Sus scrofa A0A287AW90 R-SSC-400092 https://reactome.org/PathwayBrowser/#/R-SSC-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins IEA Sus scrofa A0A287AW90 R-SSC-400097 https://reactome.org/PathwayBrowser/#/R-SSC-400097 G-beta:G-gamma inhibits Adenylate cyclase IEA Sus scrofa A0A287AW90 R-SSC-418576 https://reactome.org/PathwayBrowser/#/R-SSC-418576 Dissociation of the P2Y purinoceptor 1:Gq complex IEA Sus scrofa A0A287AW90 R-SSC-420883 https://reactome.org/PathwayBrowser/#/R-SSC-420883 Opsins act as GEFs for G alpha-t IEA Sus scrofa A0A287AW90 R-SSC-428749 https://reactome.org/PathwayBrowser/#/R-SSC-428749 Activated TP receptor binds G-proten Gq IEA Sus scrofa A0A287AW90 R-SSC-428750 https://reactome.org/PathwayBrowser/#/R-SSC-428750 Gq activation by TP receptor IEA Sus scrofa A0A287AW90 R-SSC-428752 https://reactome.org/PathwayBrowser/#/R-SSC-428752 Dissociation of the TP:Gq complex IEA Sus scrofa A0A287AW90 R-SSC-428909 https://reactome.org/PathwayBrowser/#/R-SSC-428909 Activated TP receptor binds G-protein G13 IEA Sus scrofa A0A287AW90 R-SSC-428917 https://reactome.org/PathwayBrowser/#/R-SSC-428917 G13 activation by TP receptor IEA Sus scrofa A0A287AW90 R-SSC-428918 https://reactome.org/PathwayBrowser/#/R-SSC-428918 Dissociation of the TP:G13 complex IEA Sus scrofa A0A287AW90 R-SSC-432195 https://reactome.org/PathwayBrowser/#/R-SSC-432195 AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP IEA Sus scrofa A0A287AW90 R-SSC-500717 https://reactome.org/PathwayBrowser/#/R-SSC-500717 Activation of GRIK3 homomer IEA Sus scrofa A0A287AW90 R-SSC-6814119 https://reactome.org/PathwayBrowser/#/R-SSC-6814119 TRiC/CCT binds unfolded G-protein beta subunit IEA Sus scrofa A0A287AW90 R-SSC-6814120 https://reactome.org/PathwayBrowser/#/R-SSC-6814120 ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT IEA Sus scrofa A0A287AW90 R-SSC-6814121 https://reactome.org/PathwayBrowser/#/R-SSC-6814121 PDCL binds G-protein beta and TRiC/CCT IEA Sus scrofa A0A287AW90 R-SSC-6814124 https://reactome.org/PathwayBrowser/#/R-SSC-6814124 ATP binds G-protein beta associated TRiC/CCT IEA Sus scrofa A0A287AW90 R-SSC-6814418 https://reactome.org/PathwayBrowser/#/R-SSC-6814418 PDCL promotes formation of G-beta:G-gamma heterodimers IEA Sus scrofa A0A287AW90 R-SSC-749446 https://reactome.org/PathwayBrowser/#/R-SSC-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Sus scrofa A0A287AW90 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287AW90 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287AW90 R-SSC-749453 https://reactome.org/PathwayBrowser/#/R-SSC-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Sus scrofa A0A287AW90 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287AW90 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287AW90 R-SSC-750988 https://reactome.org/PathwayBrowser/#/R-SSC-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Sus scrofa A0A287AW90 R-SSC-750993 https://reactome.org/PathwayBrowser/#/R-SSC-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Sus scrofa A0A287AW90 R-SSC-751001 https://reactome.org/PathwayBrowser/#/R-SSC-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Sus scrofa A0A287AW90 R-SSC-751019 https://reactome.org/PathwayBrowser/#/R-SSC-751019 The Ligand:GPCR:G12/13 complex dissociates IEA Sus scrofa A0A287AW90 R-SSC-751024 https://reactome.org/PathwayBrowser/#/R-SSC-751024 The Ligand:GPCR:Gz complex dissociates IEA Sus scrofa A0A287AW90 R-SSC-751027 https://reactome.org/PathwayBrowser/#/R-SSC-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Sus scrofa A0A287AW90 R-SSC-751029 https://reactome.org/PathwayBrowser/#/R-SSC-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Sus scrofa A0A287AW90 R-SSC-751039 https://reactome.org/PathwayBrowser/#/R-SSC-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Sus scrofa A0A287AW90 R-SSC-8850527 https://reactome.org/PathwayBrowser/#/R-SSC-8850527 PDCL releases folded G-beta from TRiC/CCT IEA Sus scrofa A0A287AW90 R-SSC-8850560 https://reactome.org/PathwayBrowser/#/R-SSC-8850560 G-protein alpha releases G-protein heterotrimer from PDCL IEA Sus scrofa A0A287AW90 R-SSC-8964241 https://reactome.org/PathwayBrowser/#/R-SSC-8964241 G beta-gamma complex and PIP3 recruit BTK to membrane IEA Sus scrofa A0A287AW90 R-SSC-8964271 https://reactome.org/PathwayBrowser/#/R-SSC-8964271 BTK in PIP3:BTK:G beta-gamma complex is activated IEA Sus scrofa A0A287AW90 R-SSC-8964317 https://reactome.org/PathwayBrowser/#/R-SSC-8964317 PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex IEA Sus scrofa A0A287AW90 R-SSC-8964599 https://reactome.org/PathwayBrowser/#/R-SSC-8964599 Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex IEA Sus scrofa A0A287AW90 R-SSC-8964604 https://reactome.org/PathwayBrowser/#/R-SSC-8964604 CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated IEA Sus scrofa A0A287AW90 R-SSC-8964605 https://reactome.org/PathwayBrowser/#/R-SSC-8964605 PAK1:ARHGEF6 complex binds G-protein beta-gamma complex IEA Sus scrofa A0A287AW90 R-SSC-8964614 https://reactome.org/PathwayBrowser/#/R-SSC-8964614 PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated IEA Sus scrofa A0A287AW90 R-SSC-8964634 https://reactome.org/PathwayBrowser/#/R-SSC-8964634 CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex IEA Sus scrofa A0A287AW90 R-SSC-8982637 https://reactome.org/PathwayBrowser/#/R-SSC-8982637 Opsins binds G alpha-t IEA Sus scrofa A0A287AW90 R-SSC-8982640 https://reactome.org/PathwayBrowser/#/R-SSC-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) IEA Sus scrofa A0A287AW90 R-SSC-9021596 https://reactome.org/PathwayBrowser/#/R-SSC-9021596 Membrane estrogen receptors bind SRC IEA Sus scrofa A0A287AW90 R-SSC-9021600 https://reactome.org/PathwayBrowser/#/R-SSC-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Sus scrofa A0A287AW90 R-SSC-9021601 https://reactome.org/PathwayBrowser/#/R-SSC-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Sus scrofa A0A287AW90 R-SSC-9036301 https://reactome.org/PathwayBrowser/#/R-SSC-9036301 ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s IEA Sus scrofa A0A287AW90 R-SSC-9036307 https://reactome.org/PathwayBrowser/#/R-SSC-9036307 GPER:Heterotrimeric G-protein Gs binds ESTG IEA Sus scrofa A0A287AW90 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287AW90 R-SSC-9717206 https://reactome.org/PathwayBrowser/#/R-SSC-9717206 L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) IEA Sus scrofa A0A287AW90 R-SSC-9728664 https://reactome.org/PathwayBrowser/#/R-SSC-9728664 GLP1R binds GLP1R agonists IEA Sus scrofa A0A287AW90 R-SSC-9728723 https://reactome.org/PathwayBrowser/#/R-SSC-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Sus scrofa A0A287AW90 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa A0A287AW90 R-SSC-9861324 https://reactome.org/PathwayBrowser/#/R-SSC-9861324 ADM:CALCRL:RAMP2:G-alpha(s):GDP:G-beta:G-gamma exchanges GDP for GTP IEA Sus scrofa A0A287AWA9 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AWA9 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287AWA9 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AWA9 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AWB4 R-SSC-76056 https://reactome.org/PathwayBrowser/#/R-SSC-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex IEA Sus scrofa A0A287AWB4 R-SSC-83803 https://reactome.org/PathwayBrowser/#/R-SSC-83803 Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex IEA Sus scrofa A0A287AWB4 R-SSC-83805 https://reactome.org/PathwayBrowser/#/R-SSC-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex IEA Sus scrofa A0A287AWB6 R-SSC-5668414 https://reactome.org/PathwayBrowser/#/R-SSC-5668414 TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK IEA Sus scrofa A0A287AWB6 R-SSC-5668454 https://reactome.org/PathwayBrowser/#/R-SSC-5668454 K63polyUb-cIAP1,2 ubiquitinates TRAF3 IEA Sus scrofa A0A287AWB6 R-SSC-5668481 https://reactome.org/PathwayBrowser/#/R-SSC-5668481 Protesomal degradation of K48polyUb-TRAF3 IEA Sus scrofa A0A287AWB6 R-SSC-5668534 https://reactome.org/PathwayBrowser/#/R-SSC-5668534 cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK IEA Sus scrofa A0A287AWB6 R-SSC-5669023 https://reactome.org/PathwayBrowser/#/R-SSC-5669023 TWEAK binds FN14 IEA Sus scrofa A0A287AWB6 R-SSC-5676598 https://reactome.org/PathwayBrowser/#/R-SSC-5676598 TRAF2:cIAP1/2 complex binds FN14:TWEAK IEA Sus scrofa A0A287AWD3 R-SSC-2046083 https://reactome.org/PathwayBrowser/#/R-SSC-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Sus scrofa A0A287AWD3 R-SSC-2046088 https://reactome.org/PathwayBrowser/#/R-SSC-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Sus scrofa A0A287AWD3 R-SSC-2046090 https://reactome.org/PathwayBrowser/#/R-SSC-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa A0A287AWD3 R-SSC-2046094 https://reactome.org/PathwayBrowser/#/R-SSC-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Sus scrofa A0A287AWD3 R-SSC-2046095 https://reactome.org/PathwayBrowser/#/R-SSC-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Sus scrofa A0A287AWD3 R-SSC-2046100 https://reactome.org/PathwayBrowser/#/R-SSC-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Sus scrofa A0A287AWD3 R-SSC-548800 https://reactome.org/PathwayBrowser/#/R-SSC-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Sus scrofa A0A287AWF4 R-SSC-111930 https://reactome.org/PathwayBrowser/#/R-SSC-111930 Adenylate cyclase produces cAMP IEA Sus scrofa A0A287AWF4 R-SSC-170666 https://reactome.org/PathwayBrowser/#/R-SSC-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Sus scrofa A0A287AWF4 R-SSC-170671 https://reactome.org/PathwayBrowser/#/R-SSC-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Sus scrofa A0A287AWF4 R-SSC-170672 https://reactome.org/PathwayBrowser/#/R-SSC-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Sus scrofa A0A287AWF4 R-SSC-170674 https://reactome.org/PathwayBrowser/#/R-SSC-170674 Dissociation of the Gi alpha:G olf complex IEA Sus scrofa A0A287AWF4 R-SSC-170676 https://reactome.org/PathwayBrowser/#/R-SSC-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Sus scrofa A0A287AWF4 R-SSC-170677 https://reactome.org/PathwayBrowser/#/R-SSC-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Sus scrofa A0A287AWF4 R-SSC-170685 https://reactome.org/PathwayBrowser/#/R-SSC-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Sus scrofa A0A287AWF4 R-SSC-170686 https://reactome.org/PathwayBrowser/#/R-SSC-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Sus scrofa A0A287AWF4 R-SSC-392064 https://reactome.org/PathwayBrowser/#/R-SSC-392064 G alpha (z) inhibits adenylate cyclase IEA Sus scrofa A0A287AWF4 R-SSC-5610727 https://reactome.org/PathwayBrowser/#/R-SSC-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Sus scrofa A0A287AWH3 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287AWH3 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287AWH3 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287AWH3 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287AWH3 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287AWH3 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287AWH3 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287AWH3 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287AWH3 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287AWH3 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AWH3 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287AWH3 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287AWH3 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287AWH3 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287AWH3 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287AWH3 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287AWH3 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287AWH3 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287AWH3 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287AWH3 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287AWH3 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287AWH3 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287AWH3 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287AWH3 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287AWH3 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287AWH3 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287AWH3 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287AWH3 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287AWH3 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287AWH3 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287AWH3 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287AWH3 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287AWH3 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287AWH3 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287AWH3 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287AWH3 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287AWH3 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287AWH3 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287AWH3 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287AWH3 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287AWH3 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287AWH3 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287AWH3 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287AWH3 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287AWH3 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287AWH3 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287AWH3 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287AWH7 R-SSC-203973 https://reactome.org/PathwayBrowser/#/R-SSC-203973 Vesicle budding IEA Sus scrofa A0A287AWH7 R-SSC-203979 https://reactome.org/PathwayBrowser/#/R-SSC-203979 Coat Assembly IEA Sus scrofa A0A287AWH7 R-SSC-204008 https://reactome.org/PathwayBrowser/#/R-SSC-204008 SEC31:SEC13 and v-SNARE recruitment IEA Sus scrofa A0A287AWH7 R-SSC-2130731 https://reactome.org/PathwayBrowser/#/R-SSC-2130731 Formation of COPII vesicle IEA Sus scrofa A0A287AWH7 R-SSC-2213243 https://reactome.org/PathwayBrowser/#/R-SSC-2213243 Fusion of COPII vesicle with Golgi complex IEA Sus scrofa A0A287AWH7 R-SSC-5694409 https://reactome.org/PathwayBrowser/#/R-SSC-5694409 Nucleotide exchange on RAB1 IEA Sus scrofa A0A287AWH7 R-SSC-5694415 https://reactome.org/PathwayBrowser/#/R-SSC-5694415 SEC24A,B:SEC23A bind SEC22B IEA Sus scrofa A0A287AWH7 R-SSC-5694417 https://reactome.org/PathwayBrowser/#/R-SSC-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 IEA Sus scrofa A0A287AWH7 R-SSC-5694418 https://reactome.org/PathwayBrowser/#/R-SSC-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Sus scrofa A0A287AWH7 R-SSC-5694421 https://reactome.org/PathwayBrowser/#/R-SSC-5694421 PP6 dephosphorylates SEC24 IEA Sus scrofa A0A287AWH7 R-SSC-5694522 https://reactome.org/PathwayBrowser/#/R-SSC-5694522 Inner coat assembly and cargo binding IEA Sus scrofa A0A287AWH7 R-SSC-5694527 https://reactome.org/PathwayBrowser/#/R-SSC-5694527 Loss of SAR1B GTPase IEA Sus scrofa A0A287AWH7 R-SSC-983422 https://reactome.org/PathwayBrowser/#/R-SSC-983422 Disassembly of COPII coated vesicle IEA Sus scrofa A0A287AWH7 R-SSC-983424 https://reactome.org/PathwayBrowser/#/R-SSC-983424 Budding of COPII coated vesicle IEA Sus scrofa A0A287AWH7 R-SSC-983425 https://reactome.org/PathwayBrowser/#/R-SSC-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Sus scrofa A0A287AWJ2 R-SSC-9861642 https://reactome.org/PathwayBrowser/#/R-SSC-9861642 NEK1 phosphorylates ME1 IEA Sus scrofa A0A287AWK4 R-SSC-5696872 https://reactome.org/PathwayBrowser/#/R-SSC-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Sus scrofa A0A287AWK9 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AWK9 R-SSC-8952626 https://reactome.org/PathwayBrowser/#/R-SSC-8952626 AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AWK9 R-SSC-8952631 https://reactome.org/PathwayBrowser/#/R-SSC-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AWK9 R-SSC-8952638 https://reactome.org/PathwayBrowser/#/R-SSC-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AWK9 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AWK9 R-SSC-8956045 https://reactome.org/PathwayBrowser/#/R-SSC-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AWK9 R-SSC-8956099 https://reactome.org/PathwayBrowser/#/R-SSC-8956099 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 IEA Sus scrofa A0A287AWK9 R-SSC-8956103 https://reactome.org/PathwayBrowser/#/R-SSC-8956103 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha IEA Sus scrofa A0A287AWK9 R-SSC-8956106 https://reactome.org/PathwayBrowser/#/R-SSC-8956106 VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha IEA Sus scrofa A0A287AWK9 R-SSC-9755303 https://reactome.org/PathwayBrowser/#/R-SSC-9755303 26S proteasome degrades HIFalpha IEA Sus scrofa A0A287AWL8 R-SSC-5694409 https://reactome.org/PathwayBrowser/#/R-SSC-5694409 Nucleotide exchange on RAB1 IEA Sus scrofa A0A287AWL8 R-SSC-5694418 https://reactome.org/PathwayBrowser/#/R-SSC-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Sus scrofa A0A287AWM0 R-SSC-6797955 https://reactome.org/PathwayBrowser/#/R-SSC-6797955 ALDH7A1 oxidises BETALD to BET IEA Sus scrofa A0A287AWM0 R-SSC-70941 https://reactome.org/PathwayBrowser/#/R-SSC-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Sus scrofa A0A287AWN2 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287AWP6 R-SSC-194187 https://reactome.org/PathwayBrowser/#/R-SSC-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Sus scrofa A0A287AWP7 R-SSC-9632033 https://reactome.org/PathwayBrowser/#/R-SSC-9632033 CHSY1 transfers GalNAc to chondroitin IEA Sus scrofa A0A287AWP7 R-SSC-9632034 https://reactome.org/PathwayBrowser/#/R-SSC-9632034 CHSY1 transfers GlcA to chondroitin IEA Sus scrofa A0A287AWQ8 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287AWQ8 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287AWQ8 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287AWQ8 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287AWQ8 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287AWQ8 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287AWQ8 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287AWQ8 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287AWQ8 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287AWQ8 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AWQ8 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287AWQ8 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287AWQ8 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287AWQ8 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287AWQ8 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287AWQ8 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287AWQ8 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287AWQ8 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287AWQ8 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287AWQ8 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287AWQ8 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287AWQ8 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287AWQ8 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287AWQ8 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287AWQ8 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287AWQ8 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287AWQ8 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287AWQ8 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287AWQ8 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287AWQ8 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287AWQ8 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287AWQ8 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287AWQ8 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287AWQ8 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287AWQ8 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287AWQ8 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287AWQ8 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287AWQ8 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287AWQ8 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287AWQ8 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287AWQ8 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287AWQ8 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287AWQ8 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287AWQ8 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287AWQ8 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287AWQ8 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287AWQ8 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287AWQ9 R-SSC-5694409 https://reactome.org/PathwayBrowser/#/R-SSC-5694409 Nucleotide exchange on RAB1 IEA Sus scrofa A0A287AWQ9 R-SSC-5694418 https://reactome.org/PathwayBrowser/#/R-SSC-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 IEA Sus scrofa A0A287AWR1 R-SSC-433114 https://reactome.org/PathwayBrowser/#/R-SSC-433114 NaS1 co-transports sulphate and a sodium ion IEA Sus scrofa A0A287AWR7 R-SSC-8932633 https://reactome.org/PathwayBrowser/#/R-SSC-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Sus scrofa A0A287AWR7 R-SSC-9756177 https://reactome.org/PathwayBrowser/#/R-SSC-9756177 PON1,3 hydrolyse ATVL to ATV IEA Sus scrofa A0A287AWS0 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A287AWS0 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A287AWS0 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A287AWS0 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A287AWS0 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A287AWS8 R-SSC-143468 https://reactome.org/PathwayBrowser/#/R-SSC-143468 MEOS oxidizes ethanol to acetaldehyde IEA Sus scrofa A0A287AWS8 R-SSC-211881 https://reactome.org/PathwayBrowser/#/R-SSC-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Sus scrofa A0A287AWS8 R-SSC-211910 https://reactome.org/PathwayBrowser/#/R-SSC-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Sus scrofa A0A287AWS8 R-SSC-211929 https://reactome.org/PathwayBrowser/#/R-SSC-211929 CYP2C19 5-hydroxylates omeprazole IEA Sus scrofa A0A287AWS8 R-SSC-211966 https://reactome.org/PathwayBrowser/#/R-SSC-211966 CYP2D6 4-hydroxylates debrisoquine IEA Sus scrofa A0A287AWS8 R-SSC-211988 https://reactome.org/PathwayBrowser/#/R-SSC-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Sus scrofa A0A287AWS8 R-SSC-211991 https://reactome.org/PathwayBrowser/#/R-SSC-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Sus scrofa A0A287AWS8 R-SSC-212004 https://reactome.org/PathwayBrowser/#/R-SSC-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Sus scrofa A0A287AWS8 R-SSC-212005 https://reactome.org/PathwayBrowser/#/R-SSC-212005 CYP2F1 dehydrogenates 3-methylindole IEA Sus scrofa A0A287AWS8 R-SSC-2161814 https://reactome.org/PathwayBrowser/#/R-SSC-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Sus scrofa A0A287AWS8 R-SSC-2161899 https://reactome.org/PathwayBrowser/#/R-SSC-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Sus scrofa A0A287AWS8 R-SSC-76354 https://reactome.org/PathwayBrowser/#/R-SSC-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Sus scrofa A0A287AWS8 R-SSC-76397 https://reactome.org/PathwayBrowser/#/R-SSC-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Sus scrofa A0A287AWS8 R-SSC-76416 https://reactome.org/PathwayBrowser/#/R-SSC-76416 Benzene is hydroxylated to phenol IEA Sus scrofa A0A287AWS8 R-SSC-76434 https://reactome.org/PathwayBrowser/#/R-SSC-76434 Dehalogenation of carbon tetrachloride to form a free radical IEA Sus scrofa A0A287AWS8 R-SSC-76456 https://reactome.org/PathwayBrowser/#/R-SSC-76456 O-atom dealkylation of dextromethorphan IEA Sus scrofa A0A287AWS8 R-SSC-76475 https://reactome.org/PathwayBrowser/#/R-SSC-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Sus scrofa A0A287AWS8 R-SSC-9027043 https://reactome.org/PathwayBrowser/#/R-SSC-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Sus scrofa A0A287AWS8 R-SSC-9749986 https://reactome.org/PathwayBrowser/#/R-SSC-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Sus scrofa A0A287AWS8 R-SSC-9750016 https://reactome.org/PathwayBrowser/#/R-SSC-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Sus scrofa A0A287AWS8 R-SSC-9915971 https://reactome.org/PathwayBrowser/#/R-SSC-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Sus scrofa A0A287AWS8 R-SSC-9915997 https://reactome.org/PathwayBrowser/#/R-SSC-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Sus scrofa A0A287AWT1 R-SSC-376419 https://reactome.org/PathwayBrowser/#/R-SSC-376419 Formation of NR-MED1 Coactivator Complex IEA Sus scrofa A0A287AWT1 R-SSC-382096 https://reactome.org/PathwayBrowser/#/R-SSC-382096 Formation of NR-NCOR Corepressor Complex IEA Sus scrofa A0A287AWT3 R-SSC-6804441 https://reactome.org/PathwayBrowser/#/R-SSC-6804441 RNF34 or RFFL ubiquitinates phosphorylated TP53 IEA Sus scrofa A0A287AWT3 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AWT3 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287AWT3 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AWT3 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AWU0 R-SSC-1299304 https://reactome.org/PathwayBrowser/#/R-SSC-1299304 Activation of tandem pore domain in a weak inwardly rectifying K+ channels IEA Sus scrofa A0A287AWU0 R-SSC-5578910 https://reactome.org/PathwayBrowser/#/R-SSC-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Sus scrofa A0A287AWU2 R-SSC-190682 https://reactome.org/PathwayBrowser/#/R-SSC-190682 Connexin synthesis (generic) IEA Sus scrofa A0A287AWU6 R-SSC-6805546 https://reactome.org/PathwayBrowser/#/R-SSC-6805546 Keratin type I binds keratin type II IEA Sus scrofa A0A287AWU6 R-SSC-6805573 https://reactome.org/PathwayBrowser/#/R-SSC-6805573 Keratin type I/type II heterodimers form tetramers IEA Sus scrofa A0A287AWU6 R-SSC-6806610 https://reactome.org/PathwayBrowser/#/R-SSC-6806610 Keratin filament formation IEA Sus scrofa A0A287AWU6 R-SSC-6806613 https://reactome.org/PathwayBrowser/#/R-SSC-6806613 Keratin tetramers bind to form unit length filaments IEA Sus scrofa A0A287AWU6 R-SSC-6806629 https://reactome.org/PathwayBrowser/#/R-SSC-6806629 Formation of tonofilament bundles IEA Sus scrofa A0A287AWU6 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A287AWU6 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287AWU6 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A287AWU6 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A287AWY6 R-SSC-3134946 https://reactome.org/PathwayBrowser/#/R-SSC-3134946 DDX41 ubiquitination by TRIM21 IEA Sus scrofa A0A287AWY6 R-SSC-9013869 https://reactome.org/PathwayBrowser/#/R-SSC-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Sus scrofa A0A287AWY6 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A287AWY6 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A287AWZ3 R-SSC-212222 https://reactome.org/PathwayBrowser/#/R-SSC-212222 PRC2 recruits DNA methyltransferases IEA Sus scrofa A0A287AWZ3 R-SSC-212252 https://reactome.org/PathwayBrowser/#/R-SSC-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin IEA Sus scrofa A0A287AWZ3 R-SSC-212263 https://reactome.org/PathwayBrowser/#/R-SSC-212263 PRC2 trimethylates histone H3 at lysine-27 IEA Sus scrofa A0A287AWZ3 R-SSC-212269 https://reactome.org/PathwayBrowser/#/R-SSC-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Sus scrofa A0A287AWZ3 R-SSC-2172678 https://reactome.org/PathwayBrowser/#/R-SSC-2172678 PHF8 demethylates histone H4K20me1 IEA Sus scrofa A0A287AWZ3 R-SSC-2294580 https://reactome.org/PathwayBrowser/#/R-SSC-2294580 PLK1 hyperphosphorylates Condensin II complex IEA Sus scrofa A0A287AWZ3 R-SSC-2294590 https://reactome.org/PathwayBrowser/#/R-SSC-2294590 PLK1 binds phosphorylated condensin II complex IEA Sus scrofa A0A287AWZ3 R-SSC-2294600 https://reactome.org/PathwayBrowser/#/R-SSC-2294600 CDK1 phosphorylates condensin II subunit NCAPD3 IEA Sus scrofa A0A287AWZ3 R-SSC-2301205 https://reactome.org/PathwayBrowser/#/R-SSC-2301205 SETD8 monomethylates histone H4 IEA Sus scrofa A0A287AWZ3 R-SSC-3222593 https://reactome.org/PathwayBrowser/#/R-SSC-3222593 KDM6B demethylates H3K27me3 on p16INK4A promoter IEA Sus scrofa A0A287AWZ3 R-SSC-3229089 https://reactome.org/PathwayBrowser/#/R-SSC-3229089 PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter IEA Sus scrofa A0A287AWZ3 R-SSC-3229102 https://reactome.org/PathwayBrowser/#/R-SSC-3229102 p-MAPKAPK3 phosphorylates BMI1 IEA Sus scrofa A0A287AWZ3 R-SSC-3240295 https://reactome.org/PathwayBrowser/#/R-SSC-3240295 PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter IEA Sus scrofa A0A287AWZ3 R-SSC-3318415 https://reactome.org/PathwayBrowser/#/R-SSC-3318415 ATF2 acetylates histone H2B, H4 IEA Sus scrofa A0A287AWZ3 R-SSC-3662335 https://reactome.org/PathwayBrowser/#/R-SSC-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Sus scrofa A0A287AWZ3 R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa A0A287AWZ3 R-SSC-3777129 https://reactome.org/PathwayBrowser/#/R-SSC-3777129 HDAC3 containing complexes deacetylate histone IEA Sus scrofa A0A287AWZ3 R-SSC-3782637 https://reactome.org/PathwayBrowser/#/R-SSC-3782637 HDAC8 deacetylates histones IEA Sus scrofa A0A287AWZ3 R-SSC-3782655 https://reactome.org/PathwayBrowser/#/R-SSC-3782655 HDAC10 deacetylates histone IEA Sus scrofa A0A287AWZ3 R-SSC-3785711 https://reactome.org/PathwayBrowser/#/R-SSC-3785711 Telomere shortening during replicative exhaustion IEA Sus scrofa A0A287AWZ3 R-SSC-3788745 https://reactome.org/PathwayBrowser/#/R-SSC-3788745 EHMT1:EHMT2 methylates IL8 promoter IEA Sus scrofa A0A287AWZ3 R-SSC-3788748 https://reactome.org/PathwayBrowser/#/R-SSC-3788748 EHMT1:EHMT2 methylates IL6 promoter IEA Sus scrofa A0A287AWZ3 R-SSC-427337 https://reactome.org/PathwayBrowser/#/R-SSC-427337 MBD2 binds methylcytosine in chromatin IEA Sus scrofa A0A287AWZ3 R-SSC-427514 https://reactome.org/PathwayBrowser/#/R-SSC-427514 eNoSC deacetylates histone H3 IEA Sus scrofa A0A287AWZ3 R-SSC-427527 https://reactome.org/PathwayBrowser/#/R-SSC-427527 eNoSC dimethylates histone H3 at lysine-9 IEA Sus scrofa A0A287AWZ3 R-SSC-427528 https://reactome.org/PathwayBrowser/#/R-SSC-427528 Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) IEA Sus scrofa A0A287AWZ3 R-SSC-5250938 https://reactome.org/PathwayBrowser/#/R-SSC-5250938 B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 IEA Sus scrofa A0A287AWZ3 R-SSC-5578742 https://reactome.org/PathwayBrowser/#/R-SSC-5578742 AGO1,2:small RNA complexes interact with chromatin IEA Sus scrofa A0A287AWZ3 R-SSC-5625774 https://reactome.org/PathwayBrowser/#/R-SSC-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Sus scrofa A0A287AWZ3 R-SSC-5625784 https://reactome.org/PathwayBrowser/#/R-SSC-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Sus scrofa A0A287AWZ3 R-SSC-5625796 https://reactome.org/PathwayBrowser/#/R-SSC-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Sus scrofa A0A287AWZ3 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa A0A287AWZ3 R-SSC-5625848 https://reactome.org/PathwayBrowser/#/R-SSC-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa A0A287AWZ3 R-SSC-5625849 https://reactome.org/PathwayBrowser/#/R-SSC-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Sus scrofa A0A287AWZ3 R-SSC-5625870 https://reactome.org/PathwayBrowser/#/R-SSC-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa A0A287AWZ3 R-SSC-5682586 https://reactome.org/PathwayBrowser/#/R-SSC-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Sus scrofa A0A287AWZ3 R-SSC-5682588 https://reactome.org/PathwayBrowser/#/R-SSC-5682588 RNF8 binds phosphorylated MDC1 at DNA DSBs IEA Sus scrofa A0A287AWZ3 R-SSC-5682598 https://reactome.org/PathwayBrowser/#/R-SSC-5682598 ATM phosphorylates HERC2 IEA Sus scrofa A0A287AWZ3 R-SSC-5682607 https://reactome.org/PathwayBrowser/#/R-SSC-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Sus scrofa A0A287AWZ3 R-SSC-5682858 https://reactome.org/PathwayBrowser/#/R-SSC-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Sus scrofa A0A287AWZ3 R-SSC-5682863 https://reactome.org/PathwayBrowser/#/R-SSC-5682863 RNF168 binds DNA DSBs IEA Sus scrofa A0A287AWZ3 R-SSC-5682965 https://reactome.org/PathwayBrowser/#/R-SSC-5682965 WHSC1 dimethylates histone H4 on lysine K21 at DSBs IEA Sus scrofa A0A287AWZ3 R-SSC-5682967 https://reactome.org/PathwayBrowser/#/R-SSC-5682967 WHSC1 binds DNA DSBs IEA Sus scrofa A0A287AWZ3 R-SSC-5682983 https://reactome.org/PathwayBrowser/#/R-SSC-5682983 ATM phosphorylates WHSC1 IEA Sus scrofa A0A287AWZ3 R-SSC-5682992 https://reactome.org/PathwayBrowser/#/R-SSC-5682992 KDM4A,B bind H4K20Me2 IEA Sus scrofa A0A287AWZ3 R-SSC-5683077 https://reactome.org/PathwayBrowser/#/R-SSC-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Sus scrofa A0A287AWZ3 R-SSC-5683384 https://reactome.org/PathwayBrowser/#/R-SSC-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Sus scrofa A0A287AWZ3 R-SSC-5683385 https://reactome.org/PathwayBrowser/#/R-SSC-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Sus scrofa A0A287AWZ3 R-SSC-5683405 https://reactome.org/PathwayBrowser/#/R-SSC-5683405 PPP5C dephosphorylates TP53BP1 IEA Sus scrofa A0A287AWZ3 R-SSC-5683425 https://reactome.org/PathwayBrowser/#/R-SSC-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Sus scrofa A0A287AWZ3 R-SSC-5683735 https://reactome.org/PathwayBrowser/#/R-SSC-5683735 CHEK2 is recruited to DNA DSBs IEA Sus scrofa A0A287AWZ3 R-SSC-5683801 https://reactome.org/PathwayBrowser/#/R-SSC-5683801 CHEK2 phosphorylates BRCA1 IEA Sus scrofa A0A287AWZ3 R-SSC-5683964 https://reactome.org/PathwayBrowser/#/R-SSC-5683964 ATM phosphorylates EYA1-4 IEA Sus scrofa A0A287AWZ3 R-SSC-5683967 https://reactome.org/PathwayBrowser/#/R-SSC-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Sus scrofa A0A287AWZ3 R-SSC-5683986 https://reactome.org/PathwayBrowser/#/R-SSC-5683986 APBB1 and MAPK8 bind diphosphorylated H2AFX IEA Sus scrofa A0A287AWZ3 R-SSC-5684052 https://reactome.org/PathwayBrowser/#/R-SSC-5684052 PIAS4 SUMOylates MDC1 IEA Sus scrofa A0A287AWZ3 R-SSC-5686685 https://reactome.org/PathwayBrowser/#/R-SSC-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Sus scrofa A0A287AWZ3 R-SSC-5686704 https://reactome.org/PathwayBrowser/#/R-SSC-5686704 Activated ATM phosphorylates DCLRE1C IEA Sus scrofa A0A287AWZ3 R-SSC-5686900 https://reactome.org/PathwayBrowser/#/R-SSC-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Sus scrofa A0A287AWZ3 R-SSC-5690080 https://reactome.org/PathwayBrowser/#/R-SSC-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Sus scrofa A0A287AWZ3 R-SSC-5693536 https://reactome.org/PathwayBrowser/#/R-SSC-5693536 ATM phosphorylates MDC1 IEA Sus scrofa A0A287AWZ3 R-SSC-5693549 https://reactome.org/PathwayBrowser/#/R-SSC-5693549 ATM phosphorylates histone H2AFX on S139 at DNA DSBs IEA Sus scrofa A0A287AWZ3 R-SSC-5693551 https://reactome.org/PathwayBrowser/#/R-SSC-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Sus scrofa A0A287AWZ3 R-SSC-5693566 https://reactome.org/PathwayBrowser/#/R-SSC-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Sus scrofa A0A287AWZ3 R-SSC-5693583 https://reactome.org/PathwayBrowser/#/R-SSC-5693583 MDC1 associates with gamma-H2AFX at nuclear foci IEA Sus scrofa A0A287AWZ3 R-SSC-5696960 https://reactome.org/PathwayBrowser/#/R-SSC-5696960 USP49 deubiquitinates H2B IEA Sus scrofa A0A287AWZ3 R-SSC-606287 https://reactome.org/PathwayBrowser/#/R-SSC-606287 RSF complex binds the centromere IEA Sus scrofa A0A287AWZ3 R-SSC-69891 https://reactome.org/PathwayBrowser/#/R-SSC-69891 Phosphorylation and activation of CHEK2 by ATM IEA Sus scrofa A0A287AWZ3 R-SSC-73718 https://reactome.org/PathwayBrowser/#/R-SSC-73718 UBF-1 Binds rDNA Promoter IEA Sus scrofa A0A287AWZ3 R-SSC-74986 https://reactome.org/PathwayBrowser/#/R-SSC-74986 Elongation of pre-rRNA transcript IEA Sus scrofa A0A287AWZ3 R-SSC-8936481 https://reactome.org/PathwayBrowser/#/R-SSC-8936481 Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter IEA Sus scrofa A0A287AWZ3 R-SSC-8936584 https://reactome.org/PathwayBrowser/#/R-SSC-8936584 PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter IEA Sus scrofa A0A287AWZ3 R-SSC-8936608 https://reactome.org/PathwayBrowser/#/R-SSC-8936608 PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter IEA Sus scrofa A0A287AWZ3 R-SSC-8936621 https://reactome.org/PathwayBrowser/#/R-SSC-8936621 Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter IEA Sus scrofa A0A287AWZ3 R-SSC-8937016 https://reactome.org/PathwayBrowser/#/R-SSC-8937016 Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter IEA Sus scrofa A0A287AWZ3 R-SSC-8937022 https://reactome.org/PathwayBrowser/#/R-SSC-8937022 PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter IEA Sus scrofa A0A287AWZ3 R-SSC-8937050 https://reactome.org/PathwayBrowser/#/R-SSC-8937050 Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter IEA Sus scrofa A0A287AWZ3 R-SSC-8937113 https://reactome.org/PathwayBrowser/#/R-SSC-8937113 PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter IEA Sus scrofa A0A287AWZ3 R-SSC-9009065 https://reactome.org/PathwayBrowser/#/R-SSC-9009065 FOXA1 and GATA3 bind to CCND1 promoter IEA Sus scrofa A0A287AWZ3 R-SSC-9009371 https://reactome.org/PathwayBrowser/#/R-SSC-9009371 Binding of AP1 transcriptional activator complexes to CCND1 promoter IEA Sus scrofa A0A287AWZ3 R-SSC-9011949 https://reactome.org/PathwayBrowser/#/R-SSC-9011949 KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers IEA Sus scrofa A0A287AWZ3 R-SSC-9011952 https://reactome.org/PathwayBrowser/#/R-SSC-9011952 ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers IEA Sus scrofa A0A287AWZ3 R-SSC-9011981 https://reactome.org/PathwayBrowser/#/R-SSC-9011981 EP300 is recruited to MYC and BCL2 genes IEA Sus scrofa A0A287AWZ3 R-SSC-9011983 https://reactome.org/PathwayBrowser/#/R-SSC-9011983 Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes IEA Sus scrofa A0A287AWZ3 R-SSC-9011984 https://reactome.org/PathwayBrowser/#/R-SSC-9011984 KDM1A is recruited to MYC and BCL2 genes IEA Sus scrofa A0A287AWZ3 R-SSC-9011985 https://reactome.org/PathwayBrowser/#/R-SSC-9011985 KDM1A demethylates H3 on MYC and BCL genes in response to estrogen IEA Sus scrofa A0A287AWZ3 R-SSC-9012000 https://reactome.org/PathwayBrowser/#/R-SSC-9012000 NR5A2, ZNF217 and NCOA3 bind GREB1 promoter IEA Sus scrofa A0A287AWZ3 R-SSC-9629195 https://reactome.org/PathwayBrowser/#/R-SSC-9629195 NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA IEA Sus scrofa A0A287AWZ3 R-SSC-9629216 https://reactome.org/PathwayBrowser/#/R-SSC-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Sus scrofa A0A287AWZ3 R-SSC-9670101 https://reactome.org/PathwayBrowser/#/R-SSC-9670101 ATRX:DAXX binds to subtelomeric chromosomal regions IEA Sus scrofa A0A287AWZ3 R-SSC-9749197 https://reactome.org/PathwayBrowser/#/R-SSC-9749197 ORC1 binds to H4K20me2 IEA Sus scrofa A0A287AWZ3 R-SSC-9842833 https://reactome.org/PathwayBrowser/#/R-SSC-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Sus scrofa A0A287AWZ3 R-SSC-9843115 https://reactome.org/PathwayBrowser/#/R-SSC-9843115 Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci IEA Sus scrofa A0A287AWZ3 R-SSC-9843117 https://reactome.org/PathwayBrowser/#/R-SSC-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Sus scrofa A0A287AWZ3 R-SSC-9843118 https://reactome.org/PathwayBrowser/#/R-SSC-9843118 RXRA binds ligands IEA Sus scrofa A0A287AWZ3 R-SSC-9843120 https://reactome.org/PathwayBrowser/#/R-SSC-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Sus scrofa A0A287AWZ3 R-SSC-9844006 https://reactome.org/PathwayBrowser/#/R-SSC-9844006 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) IEA Sus scrofa A0A287AWZ3 R-SSC-9844057 https://reactome.org/PathwayBrowser/#/R-SSC-9844057 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome IEA Sus scrofa A0A287AX08 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287AX11 R-SSC-3257122 https://reactome.org/PathwayBrowser/#/R-SSC-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane IEA Sus scrofa A0A287AX26 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287AX39 R-SSC-156826 https://reactome.org/PathwayBrowser/#/R-SSC-156826 Dissociation of L13a from the 60s ribosomal subunit IEA Sus scrofa A0A287AX39 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A287AX39 R-SSC-6791218 https://reactome.org/PathwayBrowser/#/R-SSC-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Sus scrofa A0A287AX39 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A287AX39 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A287AX39 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A287AX39 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A287AX39 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A287AX39 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A287AX39 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A287AX39 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A287AX59 R-SSC-156826 https://reactome.org/PathwayBrowser/#/R-SSC-156826 Dissociation of L13a from the 60s ribosomal subunit IEA Sus scrofa A0A287AX59 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A287AX59 R-SSC-6791218 https://reactome.org/PathwayBrowser/#/R-SSC-6791218 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA IEA Sus scrofa A0A287AX59 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A287AX59 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A287AX59 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A287AX59 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A287AX59 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A287AX59 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A287AX59 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A287AX59 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A287AX98 R-SSC-158300 https://reactome.org/PathwayBrowser/#/R-SSC-158300 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (XIIa catalyst) IEA Sus scrofa A0A287AX98 R-SSC-158313 https://reactome.org/PathwayBrowser/#/R-SSC-158313 factor XII -> factor XIIa IEA Sus scrofa A0A287AX98 R-SSC-158357 https://reactome.org/PathwayBrowser/#/R-SSC-158357 factor XIIa binds SERPING1 IEA Sus scrofa A0A287AXA6 R-SSC-1296127 https://reactome.org/PathwayBrowser/#/R-SSC-1296127 Activation of voltage gated Potassium channels IEA Sus scrofa A0A287AXD7 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A287AXF5 R-SSC-2130478 https://reactome.org/PathwayBrowser/#/R-SSC-2130478 Interaction of invariant chain trimer and MHC II alpha beta dimer IEA Sus scrofa A0A287AXF5 R-SSC-2213241 https://reactome.org/PathwayBrowser/#/R-SSC-2213241 Formation of nonameric complex IEA Sus scrofa A0A287AXF5 R-SSC-8950342 https://reactome.org/PathwayBrowser/#/R-SSC-8950342 EBI3:CANX binds IL27 IEA Sus scrofa A0A287AXF5 R-SSC-8950362 https://reactome.org/PathwayBrowser/#/R-SSC-8950362 EBI3:CANX binds IL12A IEA Sus scrofa A0A287AXF5 R-SSC-8950387 https://reactome.org/PathwayBrowser/#/R-SSC-8950387 CANX binds EBI3 IEA Sus scrofa A0A287AXF5 R-SSC-8950398 https://reactome.org/PathwayBrowser/#/R-SSC-8950398 CANX dissociates from IL27:EBI3 IEA Sus scrofa A0A287AXF5 R-SSC-8950740 https://reactome.org/PathwayBrowser/#/R-SSC-8950740 CANX dissociates from IL12A:EBI3 IEA Sus scrofa A0A287AXF5 R-SSC-8951500 https://reactome.org/PathwayBrowser/#/R-SSC-8951500 Dissociation of CANX from nonameric complex IEA Sus scrofa A0A287AXF5 R-SSC-901047 https://reactome.org/PathwayBrowser/#/R-SSC-901047 Binding of ERp57 IEA Sus scrofa A0A287AXF5 R-SSC-983145 https://reactome.org/PathwayBrowser/#/R-SSC-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Sus scrofa A0A287AXF5 R-SSC-983146 https://reactome.org/PathwayBrowser/#/R-SSC-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Sus scrofa A0A287AXH1 R-SSC-1606273 https://reactome.org/PathwayBrowser/#/R-SSC-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Sus scrofa A0A287AXH1 R-SSC-5626981 https://reactome.org/PathwayBrowser/#/R-SSC-5626981 TNF-α:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 IEA Sus scrofa A0A287AXI2 R-SSC-1222516 https://reactome.org/PathwayBrowser/#/R-SSC-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Sus scrofa A0A287AXI2 R-SSC-5252133 https://reactome.org/PathwayBrowser/#/R-SSC-5252133 ATP6AP1 binds V-ATPase IEA Sus scrofa A0A287AXI2 R-SSC-74723 https://reactome.org/PathwayBrowser/#/R-SSC-74723 Endosome acidification IEA Sus scrofa A0A287AXI2 R-SSC-917841 https://reactome.org/PathwayBrowser/#/R-SSC-917841 Acidification of Tf:TfR1 containing endosome IEA Sus scrofa A0A287AXI2 R-SSC-9639286 https://reactome.org/PathwayBrowser/#/R-SSC-9639286 RRAGC,D exchanges GTP for GDP IEA Sus scrofa A0A287AXI2 R-SSC-9640167 https://reactome.org/PathwayBrowser/#/R-SSC-9640167 RRAGA,B exchanges GDP for GTP IEA Sus scrofa A0A287AXI2 R-SSC-9640168 https://reactome.org/PathwayBrowser/#/R-SSC-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Sus scrofa A0A287AXI2 R-SSC-9640175 https://reactome.org/PathwayBrowser/#/R-SSC-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Sus scrofa A0A287AXI2 R-SSC-9640195 https://reactome.org/PathwayBrowser/#/R-SSC-9640195 RRAGA,B hydrolyzes GTP IEA Sus scrofa A0A287AXI2 R-SSC-9645598 https://reactome.org/PathwayBrowser/#/R-SSC-9645598 RRAGC,D hydrolyzes GTP IEA Sus scrofa A0A287AXI2 R-SSC-9645608 https://reactome.org/PathwayBrowser/#/R-SSC-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Sus scrofa A0A287AXI2 R-SSC-9646468 https://reactome.org/PathwayBrowser/#/R-SSC-9646468 mTORC1 binds RHEB:GTP IEA Sus scrofa A0A287AXI5 R-SSC-9921802 https://reactome.org/PathwayBrowser/#/R-SSC-9921802 IFI6 binds HSPA5 IEA Sus scrofa A0A287AXJ0 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A287AXJ0 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A287AXJ0 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A287AXJ1 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A287AXJ1 R-SSC-6809011 https://reactome.org/PathwayBrowser/#/R-SSC-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Sus scrofa A0A287AXJ1 R-SSC-6811433 https://reactome.org/PathwayBrowser/#/R-SSC-6811433 The COG tethering complex interacts with numerous SNAREs at the Golgi membrane IEA Sus scrofa A0A287AXJ1 R-SSC-8849748 https://reactome.org/PathwayBrowser/#/R-SSC-8849748 The COG complex binds RABs at the Golgi membrane IEA Sus scrofa A0A287AXJ7 R-SSC-1855178 https://reactome.org/PathwayBrowser/#/R-SSC-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Sus scrofa A0A287AXK4 R-SSC-2028555 https://reactome.org/PathwayBrowser/#/R-SSC-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) IEA Sus scrofa A0A287AXK4 R-SSC-2028583 https://reactome.org/PathwayBrowser/#/R-SSC-2028583 Phosphorylation of YAP by LATS2 IEA Sus scrofa A0A287AXK4 R-SSC-2028589 https://reactome.org/PathwayBrowser/#/R-SSC-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) IEA Sus scrofa A0A287AXK4 R-SSC-2028598 https://reactome.org/PathwayBrowser/#/R-SSC-2028598 Phosphorylation of YAP by LATS1 IEA Sus scrofa A0A287AXK4 R-SSC-2028626 https://reactome.org/PathwayBrowser/#/R-SSC-2028626 Phosphorylated MOB1A proteins associate with LATS proteins IEA Sus scrofa A0A287AXK4 R-SSC-2028629 https://reactome.org/PathwayBrowser/#/R-SSC-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) IEA Sus scrofa A0A287AXK4 R-SSC-2028635 https://reactome.org/PathwayBrowser/#/R-SSC-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) IEA Sus scrofa A0A287AXK4 R-SSC-2028661 https://reactome.org/PathwayBrowser/#/R-SSC-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 IEA Sus scrofa A0A287AXK4 R-SSC-2028670 https://reactome.org/PathwayBrowser/#/R-SSC-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N IEA Sus scrofa A0A287AXK4 R-SSC-2028673 https://reactome.org/PathwayBrowser/#/R-SSC-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N IEA Sus scrofa A0A287AXK4 R-SSC-2028675 https://reactome.org/PathwayBrowser/#/R-SSC-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N IEA Sus scrofa A0A287AXK4 R-SSC-2028679 https://reactome.org/PathwayBrowser/#/R-SSC-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N IEA Sus scrofa A0A287AXK4 R-SSC-2060328 https://reactome.org/PathwayBrowser/#/R-SSC-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 IEA Sus scrofa A0A287AXN9 R-SSC-6805546 https://reactome.org/PathwayBrowser/#/R-SSC-6805546 Keratin type I binds keratin type II IEA Sus scrofa A0A287AXN9 R-SSC-6805573 https://reactome.org/PathwayBrowser/#/R-SSC-6805573 Keratin type I/type II heterodimers form tetramers IEA Sus scrofa A0A287AXN9 R-SSC-6806610 https://reactome.org/PathwayBrowser/#/R-SSC-6806610 Keratin filament formation IEA Sus scrofa A0A287AXN9 R-SSC-6806613 https://reactome.org/PathwayBrowser/#/R-SSC-6806613 Keratin tetramers bind to form unit length filaments IEA Sus scrofa A0A287AXN9 R-SSC-6806629 https://reactome.org/PathwayBrowser/#/R-SSC-6806629 Formation of tonofilament bundles IEA Sus scrofa A0A287AXN9 R-SSC-6809393 https://reactome.org/PathwayBrowser/#/R-SSC-6809393 Keratin filaments bind cell-cell adhesion complexes IEA Sus scrofa A0A287AXN9 R-SSC-6809663 https://reactome.org/PathwayBrowser/#/R-SSC-6809663 Formation of hair keratin fibres IEA Sus scrofa A0A287AXN9 R-SSC-6810357 https://reactome.org/PathwayBrowser/#/R-SSC-6810357 Fillagrin and keratin intermediate filaments polymerize forming a network IEA Sus scrofa A0A287AXN9 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa A0A287AXP8 R-SSC-8847887 https://reactome.org/PathwayBrowser/#/R-SSC-8847887 RAB33B:GTP binds RIC1:RGP1 IEA Sus scrofa A0A287AXP9 R-SSC-1981120 https://reactome.org/PathwayBrowser/#/R-SSC-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Sus scrofa A0A287AXP9 R-SSC-8948228 https://reactome.org/PathwayBrowser/#/R-SSC-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A287AXP9 R-SSC-8948231 https://reactome.org/PathwayBrowser/#/R-SSC-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287AXQ6 R-SSC-8854182 https://reactome.org/PathwayBrowser/#/R-SSC-8854182 TBC1D17 binds OPTN:RAB8A IEA Sus scrofa A0A287AXQ6 R-SSC-8876190 https://reactome.org/PathwayBrowser/#/R-SSC-8876190 RAB8 GEFs exchange GTP for GDP on RAB8 IEA Sus scrofa A0A287AXR0 R-SSC-109699 https://reactome.org/PathwayBrowser/#/R-SSC-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Sus scrofa A0A287AXR0 R-SSC-190256 https://reactome.org/PathwayBrowser/#/R-SSC-190256 FGFR1c binds to FGF IEA Sus scrofa A0A287AXR0 R-SSC-190265 https://reactome.org/PathwayBrowser/#/R-SSC-190265 FGFR4 binds to FGF IEA Sus scrofa A0A287AXR0 R-SSC-190268 https://reactome.org/PathwayBrowser/#/R-SSC-190268 FGFR1c binds to Klotho-bound FGF23 IEA Sus scrofa A0A287AXR0 R-SSC-190326 https://reactome.org/PathwayBrowser/#/R-SSC-190326 Autocatalytic phosphorylation of FGFR4 IEA Sus scrofa A0A287AXR0 R-SSC-190429 https://reactome.org/PathwayBrowser/#/R-SSC-190429 Autocatalytic phosphorylation of FGFR1c IEA Sus scrofa A0A287AXR0 R-SSC-191062 https://reactome.org/PathwayBrowser/#/R-SSC-191062 Autocatalytic phosphorylation of Klotho-bound FGFR1c IEA Sus scrofa A0A287AXR0 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AXR0 R-SSC-5654149 https://reactome.org/PathwayBrowser/#/R-SSC-5654149 Activated FGFR1 phosphorylates PLCG1 IEA Sus scrofa A0A287AXR0 R-SSC-5654151 https://reactome.org/PathwayBrowser/#/R-SSC-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Sus scrofa A0A287AXR0 R-SSC-5654163 https://reactome.org/PathwayBrowser/#/R-SSC-5654163 Activated FGFR4 binds PLCG1 IEA Sus scrofa A0A287AXR0 R-SSC-5654165 https://reactome.org/PathwayBrowser/#/R-SSC-5654165 p-4Y-PLCG1 dissociates from activated FGFR1 IEA Sus scrofa A0A287AXR0 R-SSC-5654167 https://reactome.org/PathwayBrowser/#/R-SSC-5654167 Activated FGFR1 binds PLCG1 IEA Sus scrofa A0A287AXR0 R-SSC-5654169 https://reactome.org/PathwayBrowser/#/R-SSC-5654169 p-4Y-PLCG1 dissociates from activated FGFR4 IEA Sus scrofa A0A287AXR0 R-SSC-5654392 https://reactome.org/PathwayBrowser/#/R-SSC-5654392 Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A287AXR0 R-SSC-5654418 https://reactome.org/PathwayBrowser/#/R-SSC-5654418 Activated FGFR4 phosphorylates FRS2 IEA Sus scrofa A0A287AXR0 R-SSC-5654422 https://reactome.org/PathwayBrowser/#/R-SSC-5654422 Activated FGFR4 binds FRS2 IEA Sus scrofa A0A287AXR0 R-SSC-5654423 https://reactome.org/PathwayBrowser/#/R-SSC-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Sus scrofa A0A287AXR0 R-SSC-5654425 https://reactome.org/PathwayBrowser/#/R-SSC-5654425 Activated FGFR4 binds SHC1 IEA Sus scrofa A0A287AXR0 R-SSC-5654426 https://reactome.org/PathwayBrowser/#/R-SSC-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A287AXR0 R-SSC-5654428 https://reactome.org/PathwayBrowser/#/R-SSC-5654428 Activated FGFR4 phosphorylates SHC1 IEA Sus scrofa A0A287AXR0 R-SSC-5654511 https://reactome.org/PathwayBrowser/#/R-SSC-5654511 FGFRL1 dimer binds FGFs IEA Sus scrofa A0A287AXR0 R-SSC-5654560 https://reactome.org/PathwayBrowser/#/R-SSC-5654560 Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2 IEA Sus scrofa A0A287AXR0 R-SSC-5654566 https://reactome.org/PathwayBrowser/#/R-SSC-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2 IEA Sus scrofa A0A287AXR0 R-SSC-5654569 https://reactome.org/PathwayBrowser/#/R-SSC-5654569 Activated FGFR1 binds FRS2 IEA Sus scrofa A0A287AXR0 R-SSC-5654571 https://reactome.org/PathwayBrowser/#/R-SSC-5654571 Activated FGFR1 binds FRS3 IEA Sus scrofa A0A287AXR0 R-SSC-5654573 https://reactome.org/PathwayBrowser/#/R-SSC-5654573 Activated FGFR1 binds SHC1 IEA Sus scrofa A0A287AXR0 R-SSC-5654575 https://reactome.org/PathwayBrowser/#/R-SSC-5654575 Activated FGFR1 phosphorylates FRS2 IEA Sus scrofa A0A287AXR0 R-SSC-5654578 https://reactome.org/PathwayBrowser/#/R-SSC-5654578 Activated FGFR1 phosphorylates FRS3 IEA Sus scrofa A0A287AXR0 R-SSC-5654582 https://reactome.org/PathwayBrowser/#/R-SSC-5654582 Activated FGFR1 phosphorylates SHC1 IEA Sus scrofa A0A287AXR0 R-SSC-5654584 https://reactome.org/PathwayBrowser/#/R-SSC-5654584 Activated FGFR1:p-FRS bind to PPTN11 IEA Sus scrofa A0A287AXR0 R-SSC-5654586 https://reactome.org/PathwayBrowser/#/R-SSC-5654586 Activated FGFR1:p-FRS binds GRB2:SOS1 IEA Sus scrofa A0A287AXR0 R-SSC-5654587 https://reactome.org/PathwayBrowser/#/R-SSC-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11 IEA Sus scrofa A0A287AXR0 R-SSC-5654591 https://reactome.org/PathwayBrowser/#/R-SSC-5654591 Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Sus scrofa A0A287AXR0 R-SSC-5654592 https://reactome.org/PathwayBrowser/#/R-SSC-5654592 Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Sus scrofa A0A287AXR0 R-SSC-5654594 https://reactome.org/PathwayBrowser/#/R-SSC-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Sus scrofa A0A287AXR0 R-SSC-5654596 https://reactome.org/PathwayBrowser/#/R-SSC-5654596 Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA IEA Sus scrofa A0A287AXR0 R-SSC-5654597 https://reactome.org/PathwayBrowser/#/R-SSC-5654597 Activated FGFR1:p-SHC1 binds GRB2:SOS1 IEA Sus scrofa A0A287AXR0 R-SSC-5654600 https://reactome.org/PathwayBrowser/#/R-SSC-5654600 Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A287AXR0 R-SSC-5654651 https://reactome.org/PathwayBrowser/#/R-SSC-5654651 Activated FGFR4 binds FRS3 IEA Sus scrofa A0A287AXR0 R-SSC-5654653 https://reactome.org/PathwayBrowser/#/R-SSC-5654653 Activated FGFR4 phosphorylates FRS3 IEA Sus scrofa A0A287AXR0 R-SSC-5654655 https://reactome.org/PathwayBrowser/#/R-SSC-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Sus scrofa A0A287AXR0 R-SSC-5654658 https://reactome.org/PathwayBrowser/#/R-SSC-5654658 Activated FGFR4:p-FRS bind to PPTN11 IEA Sus scrofa A0A287AXR0 R-SSC-5654659 https://reactome.org/PathwayBrowser/#/R-SSC-5654659 Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Sus scrofa A0A287AXR0 R-SSC-5654662 https://reactome.org/PathwayBrowser/#/R-SSC-5654662 Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Sus scrofa A0A287AXR0 R-SSC-5654663 https://reactome.org/PathwayBrowser/#/R-SSC-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A287AXR0 R-SSC-5654664 https://reactome.org/PathwayBrowser/#/R-SSC-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Sus scrofa A0A287AXR0 R-SSC-5654667 https://reactome.org/PathwayBrowser/#/R-SSC-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Sus scrofa A0A287AXR0 R-SSC-5654669 https://reactome.org/PathwayBrowser/#/R-SSC-5654669 Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA IEA Sus scrofa A0A287AXR0 R-SSC-5654672 https://reactome.org/PathwayBrowser/#/R-SSC-5654672 CBL ubiquitinates FRS2 and FGFR1 IEA Sus scrofa A0A287AXR0 R-SSC-5654673 https://reactome.org/PathwayBrowser/#/R-SSC-5654673 p-CBL:GRB2 binds p-FRS2:activated FGFR1 IEA Sus scrofa A0A287AXR0 R-SSC-5654684 https://reactome.org/PathwayBrowser/#/R-SSC-5654684 CBL ubiquitinates FRS2 and FGFR4 IEA Sus scrofa A0A287AXR0 R-SSC-5654690 https://reactome.org/PathwayBrowser/#/R-SSC-5654690 FGFR1-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AXR0 R-SSC-5654692 https://reactome.org/PathwayBrowser/#/R-SSC-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AXR0 R-SSC-5654714 https://reactome.org/PathwayBrowser/#/R-SSC-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AXR0 R-SSC-5654717 https://reactome.org/PathwayBrowser/#/R-SSC-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AXR0 R-SSC-5654734 https://reactome.org/PathwayBrowser/#/R-SSC-5654734 p-CBL:GRB2 binds p-FRS2:activated FGFR4 IEA Sus scrofa A0A287AXR0 R-SSC-5656064 https://reactome.org/PathwayBrowser/#/R-SSC-5656064 Activated FGFR1 binds FLRT1,2,3 IEA Sus scrofa A0A287AXR0 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287AXR0 R-SSC-8851619 https://reactome.org/PathwayBrowser/#/R-SSC-8851619 GALNT3 transfers GalNAc to FGF23 IEA Sus scrofa A0A287AXR0 R-SSC-8851632 https://reactome.org/PathwayBrowser/#/R-SSC-8851632 GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region IEA Sus scrofa A0A287AXR0 R-SSC-8941613 https://reactome.org/PathwayBrowser/#/R-SSC-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Sus scrofa A0A287AXR0 R-SSC-8941623 https://reactome.org/PathwayBrowser/#/R-SSC-8941623 Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Sus scrofa A0A287AXR0 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A287AXR4 R-SSC-5689000 https://reactome.org/PathwayBrowser/#/R-SSC-5689000 AADAC deacetylates PHEN IEA Sus scrofa A0A287AXU0 R-SSC-1566962 https://reactome.org/PathwayBrowser/#/R-SSC-1566962 Elastin degradation by elastin-degrading extracellular proteinases IEA Sus scrofa A0A287AXU0 R-SSC-1592387 https://reactome.org/PathwayBrowser/#/R-SSC-1592387 Fibulin binds elastic fibres IEA Sus scrofa A0A287AXU0 R-SSC-2129353 https://reactome.org/PathwayBrowser/#/R-SSC-2129353 Tropoelastin associates with microfibrils IEA Sus scrofa A0A287AXU0 R-SSC-2129375 https://reactome.org/PathwayBrowser/#/R-SSC-2129375 Elastin cross-linking by lysyl oxidase IEA Sus scrofa A0A287AXU0 R-SSC-2161282 https://reactome.org/PathwayBrowser/#/R-SSC-2161282 Elastic fibres bind associated proteins IEA Sus scrofa A0A287AXU0 R-SSC-2161293 https://reactome.org/PathwayBrowser/#/R-SSC-2161293 Tropoelastin forms aggregate globules IEA Sus scrofa A0A287AXU0 R-SSC-2514790 https://reactome.org/PathwayBrowser/#/R-SSC-2514790 Elastin degradation by MMP14 IEA Sus scrofa A0A287AXU2 R-SSC-416320 https://reactome.org/PathwayBrowser/#/R-SSC-416320 Trafficking of GluR1-containing AMPA receptors IEA Sus scrofa A0A287AXU2 R-SSC-5682794 https://reactome.org/PathwayBrowser/#/R-SSC-5682794 LGI1 binds ADAM22 and ADAM23 IEA Sus scrofa A0A287AXU5 R-SSC-176054 https://reactome.org/PathwayBrowser/#/R-SSC-176054 GST dimers conjugate GSH with cytosolic substrates IEA Sus scrofa A0A287AXU5 R-SSC-9663492 https://reactome.org/PathwayBrowser/#/R-SSC-9663492 BIL dissociates from GSTA1, FABP1 IEA Sus scrofa A0A287AXU5 R-SSC-9663511 https://reactome.org/PathwayBrowser/#/R-SSC-9663511 BIL binds GSTA1, FABP1 IEA Sus scrofa A0A287AXU5 R-SSC-9748996 https://reactome.org/PathwayBrowser/#/R-SSC-9748996 GST dimers cleave AZA to 6MP IEA Sus scrofa A0A287AXV6 R-SSC-548814 https://reactome.org/PathwayBrowser/#/R-SSC-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Sus scrofa A0A287AXZ5 R-SSC-2160931 https://reactome.org/PathwayBrowser/#/R-SSC-2160931 Disassembly of tight junctions IEA Sus scrofa A0A287AXZ5 R-SSC-2160932 https://reactome.org/PathwayBrowser/#/R-SSC-2160932 SMURF1 binds phosphorylated PARD6A IEA Sus scrofa A0A287AXZ5 R-SSC-2160935 https://reactome.org/PathwayBrowser/#/R-SSC-2160935 SMURF1 ubiquitinates RHOA IEA Sus scrofa A0A287AY00 R-SSC-9018815 https://reactome.org/PathwayBrowser/#/R-SSC-9018815 RHOT1 binds effectors at the mitochondrial outer membrane IEA Sus scrofa A0A287AY00 R-SSC-9018824 https://reactome.org/PathwayBrowser/#/R-SSC-9018824 RHOT2 binds effectors at the mitochondrial outer membrane IEA Sus scrofa A0A287AY01 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287AY01 R-SSC-391372 https://reactome.org/PathwayBrowser/#/R-SSC-391372 GNRHR binds GNRH1,2 IEA Sus scrofa A0A287AY01 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287AY01 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287AY01 R-SSC-9724290 https://reactome.org/PathwayBrowser/#/R-SSC-9724290 GNRHR2 binds GNRH1,2 IEA Sus scrofa A0A287AY18 R-SSC-5686398 https://reactome.org/PathwayBrowser/#/R-SSC-5686398 SPIDR binds BLM:TOP3A:RMI1:RMI2 IEA Sus scrofa A0A287AY18 R-SSC-9853376 https://reactome.org/PathwayBrowser/#/R-SSC-9853376 FIGNL1 binds SPIDR IEA Sus scrofa A0A287AY39 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287AY39 R-SSC-8853734 https://reactome.org/PathwayBrowser/#/R-SSC-8853734 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 IEA Sus scrofa A0A287AY39 R-SSC-8853737 https://reactome.org/PathwayBrowser/#/R-SSC-8853737 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 IEA Sus scrofa A0A287AY39 R-SSC-8853745 https://reactome.org/PathwayBrowser/#/R-SSC-8853745 RET binds GFRA1,GFRA3 IEA Sus scrofa A0A287AY39 R-SSC-8853753 https://reactome.org/PathwayBrowser/#/R-SSC-8853753 2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 IEA Sus scrofa A0A287AY39 R-SSC-8853755 https://reactome.org/PathwayBrowser/#/R-SSC-8853755 2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 IEA Sus scrofa A0A287AY39 R-SSC-8853762 https://reactome.org/PathwayBrowser/#/R-SSC-8853762 RET dimerizes IEA Sus scrofa A0A287AY39 R-SSC-8853774 https://reactome.org/PathwayBrowser/#/R-SSC-8853774 GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated IEA Sus scrofa A0A287AY39 R-SSC-8853789 https://reactome.org/PathwayBrowser/#/R-SSC-8853789 GDNF,NRTN bind RET:GFRA1,GFRA2 IEA Sus scrofa A0A287AY39 R-SSC-8853792 https://reactome.org/PathwayBrowser/#/R-SSC-8853792 RET tyrosine phosphorylation IEA Sus scrofa A0A287AY39 R-SSC-8853793 https://reactome.org/PathwayBrowser/#/R-SSC-8853793 p-5Y-RET complexes bind GRB2 IEA Sus scrofa A0A287AY39 R-SSC-8853800 https://reactome.org/PathwayBrowser/#/R-SSC-8853800 ARTN binds RET:GFRA1,GFRA3 IEA Sus scrofa A0A287AY39 R-SSC-8854897 https://reactome.org/PathwayBrowser/#/R-SSC-8854897 p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2 IEA Sus scrofa A0A287AY39 R-SSC-8854899 https://reactome.org/PathwayBrowser/#/R-SSC-8854899 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 IEA Sus scrofa A0A287AY39 R-SSC-8854905 https://reactome.org/PathwayBrowser/#/R-SSC-8854905 p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K IEA Sus scrofa A0A287AY39 R-SSC-8854908 https://reactome.org/PathwayBrowser/#/R-SSC-8854908 PKA phosphorylates RET:GDNF:GFRA dimer IEA Sus scrofa A0A287AY39 R-SSC-8854981 https://reactome.org/PathwayBrowser/#/R-SSC-8854981 SHC1 in the RET complex is phosphorylated IEA Sus scrofa A0A287AY39 R-SSC-8855508 https://reactome.org/PathwayBrowser/#/R-SSC-8855508 p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 IEA Sus scrofa A0A287AY39 R-SSC-8855564 https://reactome.org/PathwayBrowser/#/R-SSC-8855564 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 IEA Sus scrofa A0A287AY39 R-SSC-8855617 https://reactome.org/PathwayBrowser/#/R-SSC-8855617 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 IEA Sus scrofa A0A287AY39 R-SSC-8855747 https://reactome.org/PathwayBrowser/#/R-SSC-8855747 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP IEA Sus scrofa A0A287AY39 R-SSC-8855915 https://reactome.org/PathwayBrowser/#/R-SSC-8855915 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors IEA Sus scrofa A0A287AY39 R-SSC-8871226 https://reactome.org/PathwayBrowser/#/R-SSC-8871226 RET binds GFRA1,GFRA2 IEA Sus scrofa A0A287AY40 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287AY40 R-SSC-420739 https://reactome.org/PathwayBrowser/#/R-SSC-420739 GPRC6A can bind L-alpha amino acids and calcium IEA Sus scrofa A0A287AY40 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287AY40 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287AY51 R-SSC-212222 https://reactome.org/PathwayBrowser/#/R-SSC-212222 PRC2 recruits DNA methyltransferases IEA Sus scrofa A0A287AY51 R-SSC-212269 https://reactome.org/PathwayBrowser/#/R-SSC-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 IEA Sus scrofa A0A287AY51 R-SSC-5212679 https://reactome.org/PathwayBrowser/#/R-SSC-5212679 DNMT3A binds Me2sR4-HIST1H4 IEA Sus scrofa A0A287AY60 R-SSC-1454916 https://reactome.org/PathwayBrowser/#/R-SSC-1454916 The ABCC family mediates organic anion transport IEA Sus scrofa A0A287AY60 R-SSC-2142859 https://reactome.org/PathwayBrowser/#/R-SSC-2142859 Growing HA is extruded from the cell by ABCC5 IEA Sus scrofa A0A287AY60 R-SSC-9750617 https://reactome.org/PathwayBrowser/#/R-SSC-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa A0A287AY60 R-SSC-9753284 https://reactome.org/PathwayBrowser/#/R-SSC-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Sus scrofa A0A287AY74 R-SSC-70479 https://reactome.org/PathwayBrowser/#/R-SSC-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Sus scrofa A0A287AY89 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A287AYA4 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AYA4 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287AYA4 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AYA4 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AYA4 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AYA4 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AYA4 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287AYA4 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AYA4 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AYA7 R-SSC-200396 https://reactome.org/PathwayBrowser/#/R-SSC-200396 Creatine transport across the plasma membrane IEA Sus scrofa A0A287AYA7 R-SSC-352029 https://reactome.org/PathwayBrowser/#/R-SSC-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine IEA Sus scrofa A0A287AYB3 R-SSC-1296127 https://reactome.org/PathwayBrowser/#/R-SSC-1296127 Activation of voltage gated Potassium channels IEA Sus scrofa A0A287AYB4 R-SSC-1524182 https://reactome.org/PathwayBrowser/#/R-SSC-1524182 Activated PLC gamma dissociates from the PDGF receptor IEA Sus scrofa A0A287AYB4 R-SSC-1524186 https://reactome.org/PathwayBrowser/#/R-SSC-1524186 Phosphorylation of PLCgamma by PDGFR IEA Sus scrofa A0A287AYB4 R-SSC-186765 https://reactome.org/PathwayBrowser/#/R-SSC-186765 PLC-gamma binds to the active receptor IEA Sus scrofa A0A287AYB4 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa A0A287AYB4 R-SSC-186778 https://reactome.org/PathwayBrowser/#/R-SSC-186778 SHP2 binds to the active receptor IEA Sus scrofa A0A287AYB4 R-SSC-186780 https://reactome.org/PathwayBrowser/#/R-SSC-186780 PI3-kinase binds to the active receptor IEA Sus scrofa A0A287AYB4 R-SSC-186800 https://reactome.org/PathwayBrowser/#/R-SSC-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 IEA Sus scrofa A0A287AYB4 R-SSC-186819 https://reactome.org/PathwayBrowser/#/R-SSC-186819 SH2 domain of Src binds to the active receptor IEA Sus scrofa A0A287AYB4 R-SSC-186826 https://reactome.org/PathwayBrowser/#/R-SSC-186826 GRB2:SOS1 complex binds to the active receptor IEA Sus scrofa A0A287AYB4 R-SSC-186834 https://reactome.org/PathwayBrowser/#/R-SSC-186834 SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) IEA Sus scrofa A0A287AYB4 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AYB4 R-SSC-380780 https://reactome.org/PathwayBrowser/#/R-SSC-380780 Activation of Src IEA Sus scrofa A0A287AYB4 R-SSC-380782 https://reactome.org/PathwayBrowser/#/R-SSC-380782 STAT binds to the active receptor IEA Sus scrofa A0A287AYB4 R-SSC-382052 https://reactome.org/PathwayBrowser/#/R-SSC-382052 p130Cas and C3G bind PDGFR bound Crk IEA Sus scrofa A0A287AYB4 R-SSC-382055 https://reactome.org/PathwayBrowser/#/R-SSC-382055 Grb7 binds to the active PDGF receptor IEA Sus scrofa A0A287AYB4 R-SSC-382056 https://reactome.org/PathwayBrowser/#/R-SSC-382056 Crk binds to the active PDGF receptor IEA Sus scrofa A0A287AYB4 R-SSC-382058 https://reactome.org/PathwayBrowser/#/R-SSC-382058 Nck binds to the active PDGF receptor IEA Sus scrofa A0A287AYB4 R-SSC-389083 https://reactome.org/PathwayBrowser/#/R-SSC-389083 Autophosphorylation of PDGF alpha receptors IEA Sus scrofa A0A287AYB4 R-SSC-389086 https://reactome.org/PathwayBrowser/#/R-SSC-389086 Autophosphorylation of PDGF alpha/beta receptors IEA Sus scrofa A0A287AYB4 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287AYB4 R-SSC-8864036 https://reactome.org/PathwayBrowser/#/R-SSC-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Sus scrofa A0A287AYB4 R-SSC-9674093 https://reactome.org/PathwayBrowser/#/R-SSC-9674093 PDGFRs bind type I TKI IEA Sus scrofa A0A287AYB4 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa A0A287AYC4 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287AYC4 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287AYC4 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287AYC4 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287AYC4 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287AYC4 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287AYC4 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287AYC4 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287AYC4 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287AYC4 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AYC4 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287AYC4 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287AYC4 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287AYC4 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287AYC4 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287AYC4 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287AYC4 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287AYC4 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287AYC4 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287AYC4 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287AYC4 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287AYC4 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287AYC4 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287AYC4 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287AYC4 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287AYC4 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287AYC4 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287AYC4 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287AYC4 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287AYC4 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287AYC4 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287AYC4 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287AYC4 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287AYC4 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287AYC4 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287AYC4 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287AYC4 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287AYC4 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287AYC4 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287AYC4 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287AYC4 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287AYC4 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287AYC4 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287AYC4 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287AYC4 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287AYC4 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287AYC4 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287AYE2 R-SSC-9933559 https://reactome.org/PathwayBrowser/#/R-SSC-9933559 The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1 IEA Sus scrofa A0A287AYE2 R-SSC-9933575 https://reactome.org/PathwayBrowser/#/R-SSC-9933575 MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome IEA Sus scrofa A0A287AYE2 R-SSC-9933585 https://reactome.org/PathwayBrowser/#/R-SSC-9933585 RNA exosome in PAXT:PAPOLG:TENT4A,B:ZC3H3:CBCA:polyadenylated m7GpppN-RNA:PABPN1 hydrolyzes RNA IEA Sus scrofa A0A287AYE8 R-SSC-6799191 https://reactome.org/PathwayBrowser/#/R-SSC-6799191 Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex IEA Sus scrofa A0A287AYF9 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A287AYF9 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A287AYF9 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A287AYF9 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A287AYF9 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A287AYJ5 R-SSC-163809 https://reactome.org/PathwayBrowser/#/R-SSC-163809 Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus IEA Sus scrofa A0A287AYJ5 R-SSC-163843 https://reactome.org/PathwayBrowser/#/R-SSC-163843 Furin cleaves pro-GAS6 to GAS6 IEA Sus scrofa A0A287AYJ5 R-SSC-202710 https://reactome.org/PathwayBrowser/#/R-SSC-202710 MERTK receptor binds ligands (Gas6 or Protein S) IEA Sus scrofa A0A287AYJ5 R-SSC-481007 https://reactome.org/PathwayBrowser/#/R-SSC-481007 Exocytosis of platelet alpha granule contents IEA Sus scrofa A0A287AYJ5 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A287AYK0 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa A0A287AYK0 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa A0A287AYK0 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa A0A287AYK0 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa A0A287AYK0 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa A0A287AYN9 R-SSC-5623622 https://reactome.org/PathwayBrowser/#/R-SSC-5623622 RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 IEA Sus scrofa A0A287AYN9 R-SSC-5623632 https://reactome.org/PathwayBrowser/#/R-SSC-5623632 RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 IEA Sus scrofa A0A287AYN9 R-SSC-5623667 https://reactome.org/PathwayBrowser/#/R-SSC-5623667 PDPK1 phosphorylates PKN1,2,3 IEA Sus scrofa A0A287AYN9 R-SSC-5625717 https://reactome.org/PathwayBrowser/#/R-SSC-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Sus scrofa A0A287AYN9 R-SSC-5625738 https://reactome.org/PathwayBrowser/#/R-SSC-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Sus scrofa A0A287AYN9 R-SSC-5625745 https://reactome.org/PathwayBrowser/#/R-SSC-5625745 PKN1 stimulates association of AR with NCOA2 IEA Sus scrofa A0A287AYN9 R-SSC-5625774 https://reactome.org/PathwayBrowser/#/R-SSC-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Sus scrofa A0A287AYN9 R-SSC-5625784 https://reactome.org/PathwayBrowser/#/R-SSC-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Sus scrofa A0A287AYN9 R-SSC-5625796 https://reactome.org/PathwayBrowser/#/R-SSC-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Sus scrofa A0A287AYN9 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa A0A287AYN9 R-SSC-5625848 https://reactome.org/PathwayBrowser/#/R-SSC-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa A0A287AYN9 R-SSC-5625849 https://reactome.org/PathwayBrowser/#/R-SSC-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Sus scrofa A0A287AYN9 R-SSC-5625870 https://reactome.org/PathwayBrowser/#/R-SSC-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa A0A287AYN9 R-SSC-5671737 https://reactome.org/PathwayBrowser/#/R-SSC-5671737 p-T774-PKN1 binds CDC25C IEA Sus scrofa A0A287AYN9 R-SSC-5671749 https://reactome.org/PathwayBrowser/#/R-SSC-5671749 p-T774-PKN1 phosphorylates CDC25C IEA Sus scrofa A0A287AYN9 R-SSC-5671763 https://reactome.org/PathwayBrowser/#/R-SSC-5671763 p-T774-PKN1 phosphorylates PPP1R14A IEA Sus scrofa A0A287AYN9 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa A0A287AYN9 R-SSC-9013024 https://reactome.org/PathwayBrowser/#/R-SSC-9013024 RHOB binds effectors at the plasma membrane IEA Sus scrofa A0A287AYN9 R-SSC-9013110 https://reactome.org/PathwayBrowser/#/R-SSC-9013110 RHOC binds effectors at the plasma membrane IEA Sus scrofa A0A287AYN9 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A287AYP3 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AYP3 R-SSC-8952626 https://reactome.org/PathwayBrowser/#/R-SSC-8952626 AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AYP3 R-SSC-8952631 https://reactome.org/PathwayBrowser/#/R-SSC-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AYP3 R-SSC-8952638 https://reactome.org/PathwayBrowser/#/R-SSC-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AYP3 R-SSC-8955285 https://reactome.org/PathwayBrowser/#/R-SSC-8955285 COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AYP3 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AYP3 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AYP3 R-SSC-8956045 https://reactome.org/PathwayBrowser/#/R-SSC-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AYP3 R-SSC-8956099 https://reactome.org/PathwayBrowser/#/R-SSC-8956099 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 IEA Sus scrofa A0A287AYP3 R-SSC-8956103 https://reactome.org/PathwayBrowser/#/R-SSC-8956103 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha IEA Sus scrofa A0A287AYP3 R-SSC-8956106 https://reactome.org/PathwayBrowser/#/R-SSC-8956106 VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha IEA Sus scrofa A0A287AYP3 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AYP3 R-SSC-9755303 https://reactome.org/PathwayBrowser/#/R-SSC-9755303 26S proteasome degrades HIFalpha IEA Sus scrofa A0A287AYP8 R-SSC-1482539 https://reactome.org/PathwayBrowser/#/R-SSC-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Sus scrofa A0A287AYP8 R-SSC-1482635 https://reactome.org/PathwayBrowser/#/R-SSC-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Sus scrofa A0A287AYR1 R-SSC-429094 https://reactome.org/PathwayBrowser/#/R-SSC-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Sus scrofa A0A287AYR5 R-SSC-165680 https://reactome.org/PathwayBrowser/#/R-SSC-165680 Formation of active mTORC1 complex IEA Sus scrofa A0A287AYR5 R-SSC-165692 https://reactome.org/PathwayBrowser/#/R-SSC-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Sus scrofa A0A287AYR5 R-SSC-165718 https://reactome.org/PathwayBrowser/#/R-SSC-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Sus scrofa A0A287AYR5 R-SSC-380979 https://reactome.org/PathwayBrowser/#/R-SSC-380979 RHEB in mTORC1:RHEB:GTP hydrolyses GTP IEA Sus scrofa A0A287AYR5 R-SSC-447074 https://reactome.org/PathwayBrowser/#/R-SSC-447074 AMPK phosphorylates Raptor in the mTORC1 complex IEA Sus scrofa A0A287AYR5 R-SSC-5653936 https://reactome.org/PathwayBrowser/#/R-SSC-5653936 Formation of Ragulator complex IEA Sus scrofa A0A287AYR5 R-SSC-5653968 https://reactome.org/PathwayBrowser/#/R-SSC-5653968 Ragulator:Rag dimers:SLC38A9 bind mTORC1 IEA Sus scrofa A0A287AYR5 R-SSC-5653974 https://reactome.org/PathwayBrowser/#/R-SSC-5653974 Ragulator binds Rag dimers IEA Sus scrofa A0A287AYR5 R-SSC-5672010 https://reactome.org/PathwayBrowser/#/R-SSC-5672010 Active MTORC1 phosphorylates ULK1 IEA Sus scrofa A0A287AYR5 R-SSC-5672017 https://reactome.org/PathwayBrowser/#/R-SSC-5672017 Rheb in the MTORC1 complex hydrolyses GTP IEA Sus scrofa A0A287AYR5 R-SSC-5672817 https://reactome.org/PathwayBrowser/#/R-SSC-5672817 Active MTORC1 binds the ULK1 complex IEA Sus scrofa A0A287AYR5 R-SSC-5672824 https://reactome.org/PathwayBrowser/#/R-SSC-5672824 Phosphorylated AKT1S1:mTORC1 binds YWHAB IEA Sus scrofa A0A287AYR5 R-SSC-5672828 https://reactome.org/PathwayBrowser/#/R-SSC-5672828 mTORC1 phosphorylates AKT1S1 IEA Sus scrofa A0A287AYR5 R-SSC-5672843 https://reactome.org/PathwayBrowser/#/R-SSC-5672843 AKT1S1 (PRAS40) binds mTORC1 IEA Sus scrofa A0A287AYR5 R-SSC-5673768 https://reactome.org/PathwayBrowser/#/R-SSC-5673768 p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex IEA Sus scrofa A0A287AYR5 R-SSC-5674130 https://reactome.org/PathwayBrowser/#/R-SSC-5674130 MAP2Ks and MAPKs are phosphorylated at the endosome membrane IEA Sus scrofa A0A287AYR5 R-SSC-5674132 https://reactome.org/PathwayBrowser/#/R-SSC-5674132 WDR83:LAMTOR2:LAMTOR3 binds MAPK components IEA Sus scrofa A0A287AYR5 R-SSC-5675790 https://reactome.org/PathwayBrowser/#/R-SSC-5675790 MTORC1 dissociates from ULK complex IEA Sus scrofa A0A287AYR5 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A287AYR5 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A287AYR5 R-SSC-8944454 https://reactome.org/PathwayBrowser/#/R-SSC-8944454 mTORC1 phosphorylates MAF1 IEA Sus scrofa A0A287AYR5 R-SSC-8944457 https://reactome.org/PathwayBrowser/#/R-SSC-8944457 MAF1 translocates to the nucleus IEA Sus scrofa A0A287AYR5 R-SSC-8952716 https://reactome.org/PathwayBrowser/#/R-SSC-8952716 SLC38A9 binds Ragulator:Rag dimers IEA Sus scrofa A0A287AYR5 R-SSC-8952726 https://reactome.org/PathwayBrowser/#/R-SSC-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol IEA Sus scrofa A0A287AYR5 R-SSC-9639286 https://reactome.org/PathwayBrowser/#/R-SSC-9639286 RRAGC,D exchanges GTP for GDP IEA Sus scrofa A0A287AYR5 R-SSC-9640167 https://reactome.org/PathwayBrowser/#/R-SSC-9640167 RRAGA,B exchanges GDP for GTP IEA Sus scrofa A0A287AYR5 R-SSC-9640168 https://reactome.org/PathwayBrowser/#/R-SSC-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Sus scrofa A0A287AYR5 R-SSC-9640175 https://reactome.org/PathwayBrowser/#/R-SSC-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Sus scrofa A0A287AYR5 R-SSC-9640195 https://reactome.org/PathwayBrowser/#/R-SSC-9640195 RRAGA,B hydrolyzes GTP IEA Sus scrofa A0A287AYR5 R-SSC-9645598 https://reactome.org/PathwayBrowser/#/R-SSC-9645598 RRAGC,D hydrolyzes GTP IEA Sus scrofa A0A287AYR5 R-SSC-9645608 https://reactome.org/PathwayBrowser/#/R-SSC-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Sus scrofa A0A287AYR5 R-SSC-9646468 https://reactome.org/PathwayBrowser/#/R-SSC-9646468 mTORC1 binds RHEB:GTP IEA Sus scrofa A0A287AYS5 R-SSC-190682 https://reactome.org/PathwayBrowser/#/R-SSC-190682 Connexin synthesis (generic) IEA Sus scrofa A0A287AYT0 R-SSC-5690043 https://reactome.org/PathwayBrowser/#/R-SSC-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa A0A287AYV0 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287AYV0 R-SSC-445113 https://reactome.org/PathwayBrowser/#/R-SSC-445113 Urotensin-2 receptor binds urotensin-2 and 2B IEA Sus scrofa A0A287AYV0 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287AYV0 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287AYY0 R-SSC-2046083 https://reactome.org/PathwayBrowser/#/R-SSC-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Sus scrofa A0A287AYY0 R-SSC-2046088 https://reactome.org/PathwayBrowser/#/R-SSC-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Sus scrofa A0A287AYY0 R-SSC-2046094 https://reactome.org/PathwayBrowser/#/R-SSC-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Sus scrofa A0A287AYY0 R-SSC-2046100 https://reactome.org/PathwayBrowser/#/R-SSC-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Sus scrofa A0A287AYY0 R-SSC-548800 https://reactome.org/PathwayBrowser/#/R-SSC-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Sus scrofa A0A287AYY3 R-SSC-427656 https://reactome.org/PathwayBrowser/#/R-SSC-427656 SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol IEA Sus scrofa A0A287AYY5 R-SSC-9933559 https://reactome.org/PathwayBrowser/#/R-SSC-9933559 The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1 IEA Sus scrofa A0A287AYY5 R-SSC-9933575 https://reactome.org/PathwayBrowser/#/R-SSC-9933575 MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome IEA Sus scrofa A0A287AYY5 R-SSC-9933585 https://reactome.org/PathwayBrowser/#/R-SSC-9933585 RNA exosome in PAXT:PAPOLG:TENT4A,B:ZC3H3:CBCA:polyadenylated m7GpppN-RNA:PABPN1 hydrolyzes RNA IEA Sus scrofa A0A287AZ10 R-SSC-209815 https://reactome.org/PathwayBrowser/#/R-SSC-209815 Tyrosine is monoiodinated IEA Sus scrofa A0A287AZ10 R-SSC-209840 https://reactome.org/PathwayBrowser/#/R-SSC-209840 Two DITs combine to form thyroxine IEA Sus scrofa A0A287AZ10 R-SSC-209925 https://reactome.org/PathwayBrowser/#/R-SSC-209925 DIT and MIT combine to form triiodothyronine IEA Sus scrofa A0A287AZ10 R-SSC-209973 https://reactome.org/PathwayBrowser/#/R-SSC-209973 Tyrosine is diiodinated IEA Sus scrofa A0A287AZ10 R-SSC-350901 https://reactome.org/PathwayBrowser/#/R-SSC-350901 Iodide is organified IEA Sus scrofa A0A287AZ22 R-SSC-6798739 https://reactome.org/PathwayBrowser/#/R-SSC-6798739 Exocytosis of azurophil granule membrane proteins IEA Sus scrofa A0A287AZ22 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A287AZ30 R-SSC-191763 https://reactome.org/PathwayBrowser/#/R-SSC-191763 snRNP:Snurportin complex formation IEA Sus scrofa A0A287AZ30 R-SSC-191784 https://reactome.org/PathwayBrowser/#/R-SSC-191784 snRNA Cap hypermethylation IEA Sus scrofa A0A287AZ30 R-SSC-191790 https://reactome.org/PathwayBrowser/#/R-SSC-191790 Loading and methylation of Sm proteins onto SMN Complexes IEA Sus scrofa A0A287AZ30 R-SSC-191830 https://reactome.org/PathwayBrowser/#/R-SSC-191830 snRNP nuclear import and release IEA Sus scrofa A0A287AZ37 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287AZ37 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287AZ37 R-SSC-190520 https://reactome.org/PathwayBrowser/#/R-SSC-190520 Association of Golgi transport vesicles with microtubules IEA Sus scrofa A0A287AZ37 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A287AZ37 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287AZ37 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287AZ37 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287AZ37 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287AZ37 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A287AZ37 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287AZ37 R-SSC-5610733 https://reactome.org/PathwayBrowser/#/R-SSC-5610733 KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules IEA Sus scrofa A0A287AZ37 R-SSC-5610767 https://reactome.org/PathwayBrowser/#/R-SSC-5610767 The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip IEA Sus scrofa A0A287AZ37 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa A0A287AZ37 R-SSC-5618328 https://reactome.org/PathwayBrowser/#/R-SSC-5618328 ATAT acetylates microtubules IEA Sus scrofa A0A287AZ37 R-SSC-5618331 https://reactome.org/PathwayBrowser/#/R-SSC-5618331 HDAC6 deacetylates microtubules IEA Sus scrofa A0A287AZ37 R-SSC-5624949 https://reactome.org/PathwayBrowser/#/R-SSC-5624949 Assembly of the anterograde IFT train IEA Sus scrofa A0A287AZ37 R-SSC-5624952 https://reactome.org/PathwayBrowser/#/R-SSC-5624952 Assembly of the retrograde IFT train IEA Sus scrofa A0A287AZ37 R-SSC-5625416 https://reactome.org/PathwayBrowser/#/R-SSC-5625416 Anterograde IFT IEA Sus scrofa A0A287AZ37 R-SSC-5625421 https://reactome.org/PathwayBrowser/#/R-SSC-5625421 The anterograde IFT train dissociates IEA Sus scrofa A0A287AZ37 R-SSC-5625424 https://reactome.org/PathwayBrowser/#/R-SSC-5625424 The retrograde IFT train dissociates IEA Sus scrofa A0A287AZ37 R-SSC-5625426 https://reactome.org/PathwayBrowser/#/R-SSC-5625426 Retrograde IFT IEA Sus scrofa A0A287AZ37 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A287AZ37 R-SSC-5672329 https://reactome.org/PathwayBrowser/#/R-SSC-5672329 IQGAP1 binds CLIP1 and microtubules IEA Sus scrofa A0A287AZ37 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa A0A287AZ37 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A287AZ37 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa A0A287AZ37 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa A0A287AZ37 R-SSC-8852280 https://reactome.org/PathwayBrowser/#/R-SSC-8852280 GTSE1 binds microtubule lattice in interphase cells IEA Sus scrofa A0A287AZ37 R-SSC-8852298 https://reactome.org/PathwayBrowser/#/R-SSC-8852298 GTSE1 binds MAPRE1 (EB1) at microtubule plus ends IEA Sus scrofa A0A287AZ37 R-SSC-8852306 https://reactome.org/PathwayBrowser/#/R-SSC-8852306 Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends IEA Sus scrofa A0A287AZ37 R-SSC-8865774 https://reactome.org/PathwayBrowser/#/R-SSC-8865774 TTLLs polyglutamylate tubulin IEA Sus scrofa A0A287AZ37 R-SSC-8867370 https://reactome.org/PathwayBrowser/#/R-SSC-8867370 TTLL3, TTLL8, TTLL10 polyglycylate tubulin IEA Sus scrofa A0A287AZ37 R-SSC-9646679 https://reactome.org/PathwayBrowser/#/R-SSC-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Sus scrofa A0A287AZ37 R-SSC-9646685 https://reactome.org/PathwayBrowser/#/R-SSC-9646685 Aggresome dissociates from dynein and microtubule IEA Sus scrofa A0A287AZ37 R-SSC-9648017 https://reactome.org/PathwayBrowser/#/R-SSC-9648017 EML4 binds to microtubules IEA Sus scrofa A0A287AZ37 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287AZ37 R-SSC-9668419 https://reactome.org/PathwayBrowser/#/R-SSC-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Sus scrofa A0A287AZ37 R-SSC-983259 https://reactome.org/PathwayBrowser/#/R-SSC-983259 Kinesins move along microtubules consuming ATP IEA Sus scrofa A0A287AZ37 R-SSC-983266 https://reactome.org/PathwayBrowser/#/R-SSC-983266 Kinesins bind microtubules IEA Sus scrofa A0A287AZ37 R-SSC-9836404 https://reactome.org/PathwayBrowser/#/R-SSC-9836404 p-PKR dimer phosphorylates MAPT IEA Sus scrofa A0A287AZ44 R-SSC-5685606 https://reactome.org/PathwayBrowser/#/R-SSC-5685606 CLEC2D binds KLRB1 IEA Sus scrofa A0A287AZ57 R-SSC-111439 https://reactome.org/PathwayBrowser/#/R-SSC-111439 Docking of Mature Histone mRNA complex:TAP at the NPC IEA Sus scrofa A0A287AZ57 R-SSC-158441 https://reactome.org/PathwayBrowser/#/R-SSC-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC IEA Sus scrofa A0A287AZ57 R-SSC-158447 https://reactome.org/PathwayBrowser/#/R-SSC-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC IEA Sus scrofa A0A287AZ57 R-SSC-158481 https://reactome.org/PathwayBrowser/#/R-SSC-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC IEA Sus scrofa A0A287AZ57 R-SSC-158484 https://reactome.org/PathwayBrowser/#/R-SSC-158484 Release of the SLBP independent Histone mRNA from the NPC IEA Sus scrofa A0A287AZ57 R-SSC-159046 https://reactome.org/PathwayBrowser/#/R-SSC-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC IEA Sus scrofa A0A287AZ57 R-SSC-159050 https://reactome.org/PathwayBrowser/#/R-SSC-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex IEA Sus scrofa A0A287AZ57 R-SSC-191830 https://reactome.org/PathwayBrowser/#/R-SSC-191830 snRNP nuclear import and release IEA Sus scrofa A0A287AZ57 R-SSC-2990880 https://reactome.org/PathwayBrowser/#/R-SSC-2990880 NEK6/NEK7 phosphorylates NUP98 IEA Sus scrofa A0A287AZ57 R-SSC-2990882 https://reactome.org/PathwayBrowser/#/R-SSC-2990882 CDK1 phosphorylates NUP98 IEA Sus scrofa A0A287AZ57 R-SSC-3000348 https://reactome.org/PathwayBrowser/#/R-SSC-3000348 RANBP2 SUMOylates SP100 with SUMO2 IEA Sus scrofa A0A287AZ57 R-SSC-3000399 https://reactome.org/PathwayBrowser/#/R-SSC-3000399 RANBP2 SUMOylates SP100 with SUMO1 IEA Sus scrofa A0A287AZ57 R-SSC-3000411 https://reactome.org/PathwayBrowser/#/R-SSC-3000411 RANBP2 SUMOylates PML with SUMO2 IEA Sus scrofa A0A287AZ57 R-SSC-4551649 https://reactome.org/PathwayBrowser/#/R-SSC-4551649 RANBP2 SUMOylates RANBP2 with SUMO1 IEA Sus scrofa A0A287AZ57 R-SSC-4551679 https://reactome.org/PathwayBrowser/#/R-SSC-4551679 RANBP2 SUMOylates RANBP2 with SUMO2 IEA Sus scrofa A0A287AZ57 R-SSC-4570493 https://reactome.org/PathwayBrowser/#/R-SSC-4570493 RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 IEA Sus scrofa A0A287AZ57 R-SSC-4615872 https://reactome.org/PathwayBrowser/#/R-SSC-4615872 RANBP2 SUMOylates HDAC4 with SUMO1 IEA Sus scrofa A0A287AZ57 R-SSC-4615987 https://reactome.org/PathwayBrowser/#/R-SSC-4615987 RANBP2 SUMOylates HDAC4 with SUMO2,3 IEA Sus scrofa A0A287AZ57 R-SSC-4655355 https://reactome.org/PathwayBrowser/#/R-SSC-4655355 RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) IEA Sus scrofa A0A287AZ57 R-SSC-5228508 https://reactome.org/PathwayBrowser/#/R-SSC-5228508 RANBP2 SUMOylates PML with SUMO1 IEA Sus scrofa A0A287AZ57 R-SSC-5228523 https://reactome.org/PathwayBrowser/#/R-SSC-5228523 RANBP2 SUMOylates MDM2 with SUMO1 IEA Sus scrofa A0A287AZ57 R-SSC-5252041 https://reactome.org/PathwayBrowser/#/R-SSC-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm IEA Sus scrofa A0A287AZ57 R-SSC-5578744 https://reactome.org/PathwayBrowser/#/R-SSC-5578744 Importin-8 imports AGO2:miRNA into the nucleus IEA Sus scrofa A0A287AZ57 R-SSC-75097 https://reactome.org/PathwayBrowser/#/R-SSC-75097 Transport of the export-competent mRNP complex through the NPC IEA Sus scrofa A0A287AZ57 R-SSC-75098 https://reactome.org/PathwayBrowser/#/R-SSC-75098 mRNP complex dissociates from cytosolic face of NPC IEA Sus scrofa A0A287AZ57 R-SSC-77587 https://reactome.org/PathwayBrowser/#/R-SSC-77587 Docking of Mature Replication Dependent Histone mRNA with the NPC IEA Sus scrofa A0A287AZ57 R-SSC-77594 https://reactome.org/PathwayBrowser/#/R-SSC-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC IEA Sus scrofa A0A287AZ59 R-SSC-6798739 https://reactome.org/PathwayBrowser/#/R-SSC-6798739 Exocytosis of azurophil granule membrane proteins IEA Sus scrofa A0A287AZ59 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A287AZ60 R-SSC-1675994 https://reactome.org/PathwayBrowser/#/R-SSC-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Sus scrofa A0A287AZ60 R-SSC-1676203 https://reactome.org/PathwayBrowser/#/R-SSC-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Sus scrofa A0A287AZ60 R-SSC-5679206 https://reactome.org/PathwayBrowser/#/R-SSC-5679206 MTMR14, MTMR3 dephosphorylate PI3P IEA Sus scrofa A0A287AZ66 R-SSC-1236956 https://reactome.org/PathwayBrowser/#/R-SSC-1236956 Engulfment of particulate antigen into phagocytic vesicle IEA Sus scrofa A0A287AZ66 R-SSC-1236958 https://reactome.org/PathwayBrowser/#/R-SSC-1236958 Interaction of particulate antigens with dendritic cell receptors IEA Sus scrofa A0A287AZ66 R-SSC-216076 https://reactome.org/PathwayBrowser/#/R-SSC-216076 VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 IEA Sus scrofa A0A287AZ66 R-SSC-2395320 https://reactome.org/PathwayBrowser/#/R-SSC-2395320 Latent TGF-beta-1 binds integrins IEA Sus scrofa A0A287AZ66 R-SSC-2396029 https://reactome.org/PathwayBrowser/#/R-SSC-2396029 Latent TGF-beta-3 binds integrins IEA Sus scrofa A0A287AZ66 R-SSC-2426471 https://reactome.org/PathwayBrowser/#/R-SSC-2426471 VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 IEA Sus scrofa A0A287AZ66 R-SSC-2731074 https://reactome.org/PathwayBrowser/#/R-SSC-2731074 Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) IEA Sus scrofa A0A287AZ66 R-SSC-4085087 https://reactome.org/PathwayBrowser/#/R-SSC-4085087 Canstatin binds integrins alphaVbeta3, alphaVbeta5 IEA Sus scrofa A0A287AZ66 R-SSC-4088264 https://reactome.org/PathwayBrowser/#/R-SSC-4088264 Endostatin binds integrin alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 IEA Sus scrofa A0A287AZ66 R-SSC-445699 https://reactome.org/PathwayBrowser/#/R-SSC-445699 ATP Hydrolysis By Myosin IEA Sus scrofa A0A287AZ66 R-SSC-445700 https://reactome.org/PathwayBrowser/#/R-SSC-445700 Myosin Binds ATP IEA Sus scrofa A0A287AZ66 R-SSC-445704 https://reactome.org/PathwayBrowser/#/R-SSC-445704 Calcium Binds Caldesmon IEA Sus scrofa A0A287AZ66 R-SSC-445705 https://reactome.org/PathwayBrowser/#/R-SSC-445705 Release Of ADP From Myosin IEA Sus scrofa A0A287AZ88 R-SSC-448963 https://reactome.org/PathwayBrowser/#/R-SSC-448963 Interaction of MyoD:E protein with MEF2 IEA Sus scrofa A0A287AZ88 R-SSC-8956568 https://reactome.org/PathwayBrowser/#/R-SSC-8956568 RUNX1 binds the core TAL1 complex IEA Sus scrofa A0A287AZ89 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AZ89 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287AZ89 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AZ89 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287AZ89 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287AZ89 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AZ89 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287AZ89 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AZ89 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AZA7 R-SSC-1022127 https://reactome.org/PathwayBrowser/#/R-SSC-1022127 Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol IEA Sus scrofa A0A287AZA7 R-SSC-110307 https://reactome.org/PathwayBrowser/#/R-SSC-110307 REV1 binds AP-dsDNA IEA Sus scrofa A0A287AZA7 R-SSC-110308 https://reactome.org/PathwayBrowser/#/R-SSC-110308 REV1 inserts dCMP opposite to AP sites in DNA IEA Sus scrofa A0A287AZA7 R-SSC-110311 https://reactome.org/PathwayBrowser/#/R-SSC-110311 POLZ extends translesion synthesis IEA Sus scrofa A0A287AZA7 R-SSC-110316 https://reactome.org/PathwayBrowser/#/R-SSC-110316 POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template IEA Sus scrofa A0A287AZA7 R-SSC-110317 https://reactome.org/PathwayBrowser/#/R-SSC-110317 Insertion of correct bases opposite the lesion by POLH IEA Sus scrofa A0A287AZA7 R-SSC-110319 https://reactome.org/PathwayBrowser/#/R-SSC-110319 Elongation by POLH IEA Sus scrofa A0A287AZA7 R-SSC-1234159 https://reactome.org/PathwayBrowser/#/R-SSC-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Sus scrofa A0A287AZA7 R-SSC-1234163 https://reactome.org/PathwayBrowser/#/R-SSC-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Sus scrofa A0A287AZA7 R-SSC-1234172 https://reactome.org/PathwayBrowser/#/R-SSC-1234172 Nuclear VBC complex ubiquitinylates HIF-alpha IEA Sus scrofa A0A287AZA7 R-SSC-1234175 https://reactome.org/PathwayBrowser/#/R-SSC-1234175 ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol IEA Sus scrofa A0A287AZA7 R-SSC-1253282 https://reactome.org/PathwayBrowser/#/R-SSC-1253282 ERBB4 ubiquitination by WWP1/ITCH IEA Sus scrofa A0A287AZA7 R-SSC-1295621 https://reactome.org/PathwayBrowser/#/R-SSC-1295621 CBL dissociates from ubiquitinated p-SPRY2 IEA Sus scrofa A0A287AZA7 R-SSC-1358789 https://reactome.org/PathwayBrowser/#/R-SSC-1358789 Self-ubiquitination of RNF41 IEA Sus scrofa A0A287AZA7 R-SSC-1358790 https://reactome.org/PathwayBrowser/#/R-SSC-1358790 RNF41 ubiquitinates ERBB3 IEA Sus scrofa A0A287AZA7 R-SSC-1358792 https://reactome.org/PathwayBrowser/#/R-SSC-1358792 RNF41 ubiquitinates activated ERBB3 IEA Sus scrofa A0A287AZA7 R-SSC-1358795 https://reactome.org/PathwayBrowser/#/R-SSC-1358795 Deubiquitination of RNF41 by P-USP8 IEA Sus scrofa A0A287AZA7 R-SSC-1358797 https://reactome.org/PathwayBrowser/#/R-SSC-1358797 Ubiquitinated RNF41 binds P-USP8 IEA Sus scrofa A0A287AZA7 R-SSC-1363331 https://reactome.org/PathwayBrowser/#/R-SSC-1363331 Ubiquitination of p130 (RBL2) by SCF (Skp2) IEA Sus scrofa A0A287AZA7 R-SSC-1504190 https://reactome.org/PathwayBrowser/#/R-SSC-1504190 DVL is ubiquitinated by CUL3:KLHL12:RBX1 IEA Sus scrofa A0A287AZA7 R-SSC-1504193 https://reactome.org/PathwayBrowser/#/R-SSC-1504193 Ubiquitinated DVL is degraded by the proteasome IEA Sus scrofa A0A287AZA7 R-SSC-156808 https://reactome.org/PathwayBrowser/#/R-SSC-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation IEA Sus scrofa A0A287AZA7 R-SSC-156823 https://reactome.org/PathwayBrowser/#/R-SSC-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA IEA Sus scrofa A0A287AZA7 R-SSC-157849 https://reactome.org/PathwayBrowser/#/R-SSC-157849 Formation of translation initiation complexes containing mRNA that does not circularize IEA Sus scrofa A0A287AZA7 R-SSC-168915 https://reactome.org/PathwayBrowser/#/R-SSC-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex IEA Sus scrofa A0A287AZA7 R-SSC-173542 https://reactome.org/PathwayBrowser/#/R-SSC-173542 SMURF2 ubiquitinates SMAD2 IEA Sus scrofa A0A287AZA7 R-SSC-174057 https://reactome.org/PathwayBrowser/#/R-SSC-174057 Multiubiquitination of APC/C-associated Cdh1 IEA Sus scrofa A0A287AZA7 R-SSC-174058 https://reactome.org/PathwayBrowser/#/R-SSC-174058 Degradation of multiubiquitinated Cdh1 IEA Sus scrofa A0A287AZA7 R-SSC-174104 https://reactome.org/PathwayBrowser/#/R-SSC-174104 Ubiquitination of Cyclin A by APC/C:Cdc20 complex IEA Sus scrofa A0A287AZA7 R-SSC-174105 https://reactome.org/PathwayBrowser/#/R-SSC-174105 Degradation of multiubiquitinated cell cycle proteins IEA Sus scrofa A0A287AZA7 R-SSC-174144 https://reactome.org/PathwayBrowser/#/R-SSC-174144 Ubiquitination of Securin by phospho-APC/C:Cdc20 complex IEA Sus scrofa A0A287AZA7 R-SSC-174157 https://reactome.org/PathwayBrowser/#/R-SSC-174157 Degradation of multiubiquitinated Cyclin B IEA Sus scrofa A0A287AZA7 R-SSC-174159 https://reactome.org/PathwayBrowser/#/R-SSC-174159 Ubiquitination of Emi1 by SCF-beta-TrCP IEA Sus scrofa A0A287AZA7 R-SSC-174195 https://reactome.org/PathwayBrowser/#/R-SSC-174195 Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex IEA Sus scrofa A0A287AZA7 R-SSC-174202 https://reactome.org/PathwayBrowser/#/R-SSC-174202 Degradation of multiubiquitinated Securin IEA Sus scrofa A0A287AZA7 R-SSC-174227 https://reactome.org/PathwayBrowser/#/R-SSC-174227 Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex IEA Sus scrofa A0A287AZA7 R-SSC-174255 https://reactome.org/PathwayBrowser/#/R-SSC-174255 Degradation multiubiquitinated Cyclin A IEA Sus scrofa A0A287AZA7 R-SSC-179417 https://reactome.org/PathwayBrowser/#/R-SSC-179417 Multiubiquitination of Nek2A IEA Sus scrofa A0A287AZA7 R-SSC-179421 https://reactome.org/PathwayBrowser/#/R-SSC-179421 Degradation of multiubiquitinated Nek2A IEA Sus scrofa A0A287AZA7 R-SSC-1799332 https://reactome.org/PathwayBrowser/#/R-SSC-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) IEA Sus scrofa A0A287AZA7 R-SSC-182986 https://reactome.org/PathwayBrowser/#/R-SSC-182986 CBL-mediated ubiquitination of CIN85 IEA Sus scrofa A0A287AZA7 R-SSC-182993 https://reactome.org/PathwayBrowser/#/R-SSC-182993 Ubiquitination of stimulated EGFR (CBL) IEA Sus scrofa A0A287AZA7 R-SSC-183036 https://reactome.org/PathwayBrowser/#/R-SSC-183036 Ubiquitination of stimulated EGFR (CBL:GRB2) IEA Sus scrofa A0A287AZA7 R-SSC-183051 https://reactome.org/PathwayBrowser/#/R-SSC-183051 CBL ubiquitinates Sprouty IEA Sus scrofa A0A287AZA7 R-SSC-183084 https://reactome.org/PathwayBrowser/#/R-SSC-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Sus scrofa A0A287AZA7 R-SSC-183089 https://reactome.org/PathwayBrowser/#/R-SSC-183089 CBL binds and ubiquitinates phosphorylated Sprouty IEA Sus scrofa A0A287AZA7 R-SSC-187574 https://reactome.org/PathwayBrowser/#/R-SSC-187574 Degradation of ubiquitinated p27/p21 by the 26S proteasome IEA Sus scrofa A0A287AZA7 R-SSC-187575 https://reactome.org/PathwayBrowser/#/R-SSC-187575 Ubiquitination of phospho-p27/p21 IEA Sus scrofa A0A287AZA7 R-SSC-188191 https://reactome.org/PathwayBrowser/#/R-SSC-188191 APC/C:Cdh1-mediated degradation of Skp2 IEA Sus scrofa A0A287AZA7 R-SSC-1912357 https://reactome.org/PathwayBrowser/#/R-SSC-1912357 ITCH ubiquitinates DTX IEA Sus scrofa A0A287AZA7 R-SSC-1918092 https://reactome.org/PathwayBrowser/#/R-SSC-1918092 CHIP (STUB1) mediates ubiquitination of ERBB2 IEA Sus scrofa A0A287AZA7 R-SSC-1918095 https://reactome.org/PathwayBrowser/#/R-SSC-1918095 CUL5 mediates ubiquitination of ERBB2 IEA Sus scrofa A0A287AZA7 R-SSC-1977296 https://reactome.org/PathwayBrowser/#/R-SSC-1977296 NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer IEA Sus scrofa A0A287AZA7 R-SSC-202453 https://reactome.org/PathwayBrowser/#/R-SSC-202453 Auto-ubiquitination of TRAF6 IEA Sus scrofa A0A287AZA7 R-SSC-202534 https://reactome.org/PathwayBrowser/#/R-SSC-202534 Ubiquitination of NEMO by TRAF6 IEA Sus scrofa A0A287AZA7 R-SSC-209061 https://reactome.org/PathwayBrowser/#/R-SSC-209061 Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex IEA Sus scrofa A0A287AZA7 R-SSC-209063 https://reactome.org/PathwayBrowser/#/R-SSC-209063 Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex IEA Sus scrofa A0A287AZA7 R-SSC-209536 https://reactome.org/PathwayBrowser/#/R-SSC-209536 IkB is ubiquitinated and degraded IEA Sus scrofa A0A287AZA7 R-SSC-209566 https://reactome.org/PathwayBrowser/#/R-SSC-209566 TRAF6 is auto-ubiquitinated IEA Sus scrofa A0A287AZA7 R-SSC-2130282 https://reactome.org/PathwayBrowser/#/R-SSC-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Sus scrofa A0A287AZA7 R-SSC-2130286 https://reactome.org/PathwayBrowser/#/R-SSC-2130286 Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) IEA Sus scrofa A0A287AZA7 R-SSC-2160931 https://reactome.org/PathwayBrowser/#/R-SSC-2160931 Disassembly of tight junctions IEA Sus scrofa A0A287AZA7 R-SSC-2160935 https://reactome.org/PathwayBrowser/#/R-SSC-2160935 SMURF1 ubiquitinates RHOA IEA Sus scrofa A0A287AZA7 R-SSC-2169046 https://reactome.org/PathwayBrowser/#/R-SSC-2169046 Degradation of TGF-beta receptor complex IEA Sus scrofa A0A287AZA7 R-SSC-2176452 https://reactome.org/PathwayBrowser/#/R-SSC-2176452 Degradation of ubiquitinated SMAD2 IEA Sus scrofa A0A287AZA7 R-SSC-2176502 https://reactome.org/PathwayBrowser/#/R-SSC-2176502 NEDD4L ubiquitinates SMAD2/3 IEA Sus scrofa A0A287AZA7 R-SSC-2176503 https://reactome.org/PathwayBrowser/#/R-SSC-2176503 Degradation of SMAD2/3:SMAD4 complex IEA Sus scrofa A0A287AZA7 R-SSC-2179276 https://reactome.org/PathwayBrowser/#/R-SSC-2179276 SMURF2 monoubiquitinates SMAD3 IEA Sus scrofa A0A287AZA7 R-SSC-2186767 https://reactome.org/PathwayBrowser/#/R-SSC-2186767 Degradation of ubiquitinated SKI/SKIL IEA Sus scrofa A0A287AZA7 R-SSC-2186780 https://reactome.org/PathwayBrowser/#/R-SSC-2186780 Degradation of Ub-SMAD7 IEA Sus scrofa A0A287AZA7 R-SSC-2187368 https://reactome.org/PathwayBrowser/#/R-SSC-2187368 STUB1 (CHIP) ubiquitinates SMAD3 IEA Sus scrofa A0A287AZA7 R-SSC-2187382 https://reactome.org/PathwayBrowser/#/R-SSC-2187382 Degradation of ubiquitinated SMAD3 IEA Sus scrofa A0A287AZA7 R-SSC-2213017 https://reactome.org/PathwayBrowser/#/R-SSC-2213017 Auto-ubiquitination of TRAF3 IEA Sus scrofa A0A287AZA7 R-SSC-264444 https://reactome.org/PathwayBrowser/#/R-SSC-264444 Autoubiquitination of phospho-COP1(Ser-387 ) IEA Sus scrofa A0A287AZA7 R-SSC-264458 https://reactome.org/PathwayBrowser/#/R-SSC-264458 Proteasome mediated degradation of COP1 IEA Sus scrofa A0A287AZA7 R-SSC-2730904 https://reactome.org/PathwayBrowser/#/R-SSC-2730904 Auto-ubiquitination of TRAF6 IEA Sus scrofa A0A287AZA7 R-SSC-3134804 https://reactome.org/PathwayBrowser/#/R-SSC-3134804 STING ubiquitination by TRIM32 or TRIM56 IEA Sus scrofa A0A287AZA7 R-SSC-3134946 https://reactome.org/PathwayBrowser/#/R-SSC-3134946 DDX41 ubiquitination by TRIM21 IEA Sus scrofa A0A287AZA7 R-SSC-3215295 https://reactome.org/PathwayBrowser/#/R-SSC-3215295 USP7 deubiquitinates MDM2 IEA Sus scrofa A0A287AZA7 R-SSC-3215310 https://reactome.org/PathwayBrowser/#/R-SSC-3215310 USP7 deubiquitinates TP53 and counteracts MDM2 IEA Sus scrofa A0A287AZA7 R-SSC-3322429 https://reactome.org/PathwayBrowser/#/R-SSC-3322429 XIAP monoubiquinates TLE IEA Sus scrofa A0A287AZA7 R-SSC-3640861 https://reactome.org/PathwayBrowser/#/R-SSC-3640861 RNF146 ubiquitinates ADP-ribosylated AXIN IEA Sus scrofa A0A287AZA7 R-SSC-3640872 https://reactome.org/PathwayBrowser/#/R-SSC-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Sus scrofa A0A287AZA7 R-SSC-3640874 https://reactome.org/PathwayBrowser/#/R-SSC-3640874 Ub-RibC-AXIN is degraded by the proteasome IEA Sus scrofa A0A287AZA7 R-SSC-3788724 https://reactome.org/PathwayBrowser/#/R-SSC-3788724 Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 IEA Sus scrofa A0A287AZA7 R-SSC-446877 https://reactome.org/PathwayBrowser/#/R-SSC-446877 TRAF6 is K63 poly-ubiquitinated IEA Sus scrofa A0A287AZA7 R-SSC-450337 https://reactome.org/PathwayBrowser/#/R-SSC-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Sus scrofa A0A287AZA7 R-SSC-450346 https://reactome.org/PathwayBrowser/#/R-SSC-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Sus scrofa A0A287AZA7 R-SSC-450358 https://reactome.org/PathwayBrowser/#/R-SSC-450358 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation IEA Sus scrofa A0A287AZA7 R-SSC-450580 https://reactome.org/PathwayBrowser/#/R-SSC-450580 AUF1 (hnRNP D0) is ubiquitinylated IEA Sus scrofa A0A287AZA7 R-SSC-451418 https://reactome.org/PathwayBrowser/#/R-SSC-451418 Pellino ubiquitinates IRAK1 IEA Sus scrofa A0A287AZA7 R-SSC-4608852 https://reactome.org/PathwayBrowser/#/R-SSC-4608852 SMURF1/2 ubiquitinates PRICKLE1 IEA Sus scrofa A0A287AZA7 R-SSC-4641129 https://reactome.org/PathwayBrowser/#/R-SSC-4641129 AXIN is ubiquitinated by SMURF2 IEA Sus scrofa A0A287AZA7 R-SSC-4641159 https://reactome.org/PathwayBrowser/#/R-SSC-4641159 DVL1 is ubiquitinated by HECW1 IEA Sus scrofa A0A287AZA7 R-SSC-4641236 https://reactome.org/PathwayBrowser/#/R-SSC-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Sus scrofa A0A287AZA7 R-SSC-4641246 https://reactome.org/PathwayBrowser/#/R-SSC-4641246 ZNRF3 autoubiquitinates to promote its internalization IEA Sus scrofa A0A287AZA7 R-SSC-4641253 https://reactome.org/PathwayBrowser/#/R-SSC-4641253 ZNRF3 ubiquitinates FZD to promote its downregulation IEA Sus scrofa A0A287AZA7 R-SSC-4641256 https://reactome.org/PathwayBrowser/#/R-SSC-4641256 Ubiquitinated AXIN is degraded by the proteasome IEA Sus scrofa A0A287AZA7 R-SSC-4641260 https://reactome.org/PathwayBrowser/#/R-SSC-4641260 Ubiquitinated DVL1 is degraded by the proteasome IEA Sus scrofa A0A287AZA7 R-SSC-5357757 https://reactome.org/PathwayBrowser/#/R-SSC-5357757 BIRC(cIAP1/2) ubiquitinates RIPK1 IEA Sus scrofa A0A287AZA7 R-SSC-5357845 https://reactome.org/PathwayBrowser/#/R-SSC-5357845 K63polyUb-RIPK1 is deubiquitinated IEA Sus scrofa A0A287AZA7 R-SSC-5362412 https://reactome.org/PathwayBrowser/#/R-SSC-5362412 SYVN1 ubiquitinates Hh C-terminal fragments IEA Sus scrofa A0A287AZA7 R-SSC-5362448 https://reactome.org/PathwayBrowser/#/R-SSC-5362448 Hh C-terminal fragments are degraded by the proteasome IEA Sus scrofa A0A287AZA7 R-SSC-5362500 https://reactome.org/PathwayBrowser/#/R-SSC-5362500 TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Sus scrofa A0A287AZA7 R-SSC-5607731 https://reactome.org/PathwayBrowser/#/R-SSC-5607731 26S proteasome processes p-7S-p100:RELB to form p52:RELB IEA Sus scrofa A0A287AZA7 R-SSC-5607756 https://reactome.org/PathwayBrowser/#/R-SSC-5607756 TRAF6 oligomer autoubiquitinates IEA Sus scrofa A0A287AZA7 R-SSC-5607757 https://reactome.org/PathwayBrowser/#/R-SSC-5607757 K63polyUb-TRAF6 ubiquitinates TAK1 IEA Sus scrofa A0A287AZA7 R-SSC-5610742 https://reactome.org/PathwayBrowser/#/R-SSC-5610742 SCF(beta-TrCP) ubiquitinates p-GLI1 IEA Sus scrofa A0A287AZA7 R-SSC-5610746 https://reactome.org/PathwayBrowser/#/R-SSC-5610746 SCF(beta-TrCP) ubiquitinates p-GLI3 IEA Sus scrofa A0A287AZA7 R-SSC-5635854 https://reactome.org/PathwayBrowser/#/R-SSC-5635854 GLI2,3 are degraded by the proteasome IEA Sus scrofa A0A287AZA7 R-SSC-5635856 https://reactome.org/PathwayBrowser/#/R-SSC-5635856 SPOP:CUL3:RBX1 ubiquitinates GLI2,3 IEA Sus scrofa A0A287AZA7 R-SSC-5635864 https://reactome.org/PathwayBrowser/#/R-SSC-5635864 NUMB:ITCH ubiquitinates GLI1 IEA Sus scrofa A0A287AZA7 R-SSC-5635868 https://reactome.org/PathwayBrowser/#/R-SSC-5635868 ub-GLI is degraded by the proteasome IEA Sus scrofa A0A287AZA7 R-SSC-5652009 https://reactome.org/PathwayBrowser/#/R-SSC-5652009 RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA IEA Sus scrofa A0A287AZA7 R-SSC-5652151 https://reactome.org/PathwayBrowser/#/R-SSC-5652151 REV1 recruits POLZ to (AP:Cyt)-DNA Template IEA Sus scrofa A0A287AZA7 R-SSC-5653754 https://reactome.org/PathwayBrowser/#/R-SSC-5653754 UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA IEA Sus scrofa A0A287AZA7 R-SSC-5653756 https://reactome.org/PathwayBrowser/#/R-SSC-5653756 TRIM25 binds monoUb:164-PCNA IEA Sus scrofa A0A287AZA7 R-SSC-5653766 https://reactome.org/PathwayBrowser/#/R-SSC-5653766 USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A287AZA7 R-SSC-5653770 https://reactome.org/PathwayBrowser/#/R-SSC-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Sus scrofa A0A287AZA7 R-SSC-5653838 https://reactome.org/PathwayBrowser/#/R-SSC-5653838 POLD,POLE binds deISGylated PCNA after TLS IEA Sus scrofa A0A287AZA7 R-SSC-5654672 https://reactome.org/PathwayBrowser/#/R-SSC-5654672 CBL ubiquitinates FRS2 and FGFR1 IEA Sus scrofa A0A287AZA7 R-SSC-5654677 https://reactome.org/PathwayBrowser/#/R-SSC-5654677 CBL ubiquitinates FRS2 and FGFR2 IEA Sus scrofa A0A287AZA7 R-SSC-5654679 https://reactome.org/PathwayBrowser/#/R-SSC-5654679 CBL ubiquitinates FRS2 and FGFR3 IEA Sus scrofa A0A287AZA7 R-SSC-5654684 https://reactome.org/PathwayBrowser/#/R-SSC-5654684 CBL ubiquitinates FRS2 and FGFR4 IEA Sus scrofa A0A287AZA7 R-SSC-5654985 https://reactome.org/PathwayBrowser/#/R-SSC-5654985 SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH IEA Sus scrofa A0A287AZA7 R-SSC-5654986 https://reactome.org/PathwayBrowser/#/R-SSC-5654986 SPRTN binds monoUb:K164-PCNA associated with POLH IEA Sus scrofa A0A287AZA7 R-SSC-5654989 https://reactome.org/PathwayBrowser/#/R-SSC-5654989 SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA IEA Sus scrofa A0A287AZA7 R-SSC-5655170 https://reactome.org/PathwayBrowser/#/R-SSC-5655170 RCHY1 monoubiquitinates POLH IEA Sus scrofa A0A287AZA7 R-SSC-5655193 https://reactome.org/PathwayBrowser/#/R-SSC-5655193 KIAA0101 double monoubiquitination IEA Sus scrofa A0A287AZA7 R-SSC-5655466 https://reactome.org/PathwayBrowser/#/R-SSC-5655466 USP1:WDR48 deubiquitinates monoUb:K164-PCNA IEA Sus scrofa A0A287AZA7 R-SSC-5655481 https://reactome.org/PathwayBrowser/#/R-SSC-5655481 USP1:WDR48 binds monoUb:K164-PCNA IEA Sus scrofa A0A287AZA7 R-SSC-5655835 https://reactome.org/PathwayBrowser/#/R-SSC-5655835 POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template IEA Sus scrofa A0A287AZA7 R-SSC-5655892 https://reactome.org/PathwayBrowser/#/R-SSC-5655892 POLK incorporates dNMP opposite to damaged DNA base IEA Sus scrofa A0A287AZA7 R-SSC-5655965 https://reactome.org/PathwayBrowser/#/R-SSC-5655965 POLK and POLZ cooperate in elongation of mispaired primer termini IEA Sus scrofa A0A287AZA7 R-SSC-5656105 https://reactome.org/PathwayBrowser/#/R-SSC-5656105 POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA IEA Sus scrofa A0A287AZA7 R-SSC-5656148 https://reactome.org/PathwayBrowser/#/R-SSC-5656148 POLI incorporates dNMP opposite to damaged DNA base IEA Sus scrofa A0A287AZA7 R-SSC-5656158 https://reactome.org/PathwayBrowser/#/R-SSC-5656158 POLZ elongates POLI-incorporated dNMP IEA Sus scrofa A0A287AZA7 R-SSC-5658424 https://reactome.org/PathwayBrowser/#/R-SSC-5658424 KBTBD7:CUL3:RBX1 ubiquitinates NF1 IEA Sus scrofa A0A287AZA7 R-SSC-5668414 https://reactome.org/PathwayBrowser/#/R-SSC-5668414 TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK IEA Sus scrofa A0A287AZA7 R-SSC-5668454 https://reactome.org/PathwayBrowser/#/R-SSC-5668454 K63polyUb-cIAP1,2 ubiquitinates TRAF3 IEA Sus scrofa A0A287AZA7 R-SSC-5668534 https://reactome.org/PathwayBrowser/#/R-SSC-5668534 cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK IEA Sus scrofa A0A287AZA7 R-SSC-5674022 https://reactome.org/PathwayBrowser/#/R-SSC-5674022 BRAP autoubiquitinates IEA Sus scrofa A0A287AZA7 R-SSC-5675470 https://reactome.org/PathwayBrowser/#/R-SSC-5675470 BIRC2/3 (cIAP1/2) is autoubiquitinated IEA Sus scrofa A0A287AZA7 R-SSC-5682858 https://reactome.org/PathwayBrowser/#/R-SSC-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Sus scrofa A0A287AZA7 R-SSC-5683077 https://reactome.org/PathwayBrowser/#/R-SSC-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Sus scrofa A0A287AZA7 R-SSC-5684273 https://reactome.org/PathwayBrowser/#/R-SSC-5684273 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 IEA Sus scrofa A0A287AZA7 R-SSC-5687112 https://reactome.org/PathwayBrowser/#/R-SSC-5687112 MAPK6 is degraded by the 26S proteasome IEA Sus scrofa A0A287AZA7 R-SSC-5688797 https://reactome.org/PathwayBrowser/#/R-SSC-5688797 ATXN3 family cleave Ub chains IEA Sus scrofa A0A287AZA7 R-SSC-5689861 https://reactome.org/PathwayBrowser/#/R-SSC-5689861 Recruitment of XPA and release of CAK IEA Sus scrofa A0A287AZA7 R-SSC-5689950 https://reactome.org/PathwayBrowser/#/R-SSC-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Sus scrofa A0A287AZA7 R-SSC-5689973 https://reactome.org/PathwayBrowser/#/R-SSC-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Sus scrofa A0A287AZA7 R-SSC-5690080 https://reactome.org/PathwayBrowser/#/R-SSC-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Sus scrofa A0A287AZA7 R-SSC-5690152 https://reactome.org/PathwayBrowser/#/R-SSC-5690152 USP5 cleaves polyubiquitin IEA Sus scrofa A0A287AZA7 R-SSC-5690157 https://reactome.org/PathwayBrowser/#/R-SSC-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Sus scrofa A0A287AZA7 R-SSC-5690159 https://reactome.org/PathwayBrowser/#/R-SSC-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Sus scrofa A0A287AZA7 R-SSC-5690196 https://reactome.org/PathwayBrowser/#/R-SSC-5690196 USP8 deubiquitinates RNF128 IEA Sus scrofa A0A287AZA7 R-SSC-5690213 https://reactome.org/PathwayBrowser/#/R-SSC-5690213 DNA polymerases delta, epsilon or kappa bind the GG-NER site IEA Sus scrofa A0A287AZA7 R-SSC-5690319 https://reactome.org/PathwayBrowser/#/R-SSC-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Sus scrofa A0A287AZA7 R-SSC-5690759 https://reactome.org/PathwayBrowser/#/R-SSC-5690759 BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 IEA Sus scrofa A0A287AZA7 R-SSC-5690790 https://reactome.org/PathwayBrowser/#/R-SSC-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Sus scrofa A0A287AZA7 R-SSC-5690827 https://reactome.org/PathwayBrowser/#/R-SSC-5690827 TNFAIP3 (A20) ubiquitinates RIPK1 IEA Sus scrofa A0A287AZA7 R-SSC-5690856 https://reactome.org/PathwayBrowser/#/R-SSC-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Sus scrofa A0A287AZA7 R-SSC-5690870 https://reactome.org/PathwayBrowser/#/R-SSC-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Sus scrofa A0A287AZA7 R-SSC-5690988 https://reactome.org/PathwayBrowser/#/R-SSC-5690988 3'-incision of DNA by ERCC5 (XPG) in GG-NER IEA Sus scrofa A0A287AZA7 R-SSC-5690996 https://reactome.org/PathwayBrowser/#/R-SSC-5690996 ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA IEA Sus scrofa A0A287AZA7 R-SSC-5691000 https://reactome.org/PathwayBrowser/#/R-SSC-5691000 TFIIH binds GG-NER site to form a verification complex IEA Sus scrofa A0A287AZA7 R-SSC-5691001 https://reactome.org/PathwayBrowser/#/R-SSC-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER IEA Sus scrofa A0A287AZA7 R-SSC-5691108 https://reactome.org/PathwayBrowser/#/R-SSC-5691108 SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 IEA Sus scrofa A0A287AZA7 R-SSC-5691381 https://reactome.org/PathwayBrowser/#/R-SSC-5691381 MYSM1 deubiquitinates Histone H2A IEA Sus scrofa A0A287AZA7 R-SSC-5691411 https://reactome.org/PathwayBrowser/#/R-SSC-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Sus scrofa A0A287AZA7 R-SSC-5691431 https://reactome.org/PathwayBrowser/#/R-SSC-5691431 PSMD14 cleaves K63-linked ubiquitin IEA Sus scrofa A0A287AZA7 R-SSC-5691439 https://reactome.org/PathwayBrowser/#/R-SSC-5691439 BRISC complex deubiquitinates NLRP3 IEA Sus scrofa A0A287AZA7 R-SSC-5693108 https://reactome.org/PathwayBrowser/#/R-SSC-5693108 TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains IEA Sus scrofa A0A287AZA7 R-SSC-5693593 https://reactome.org/PathwayBrowser/#/R-SSC-5693593 D-loop extension by DNA polymerases IEA Sus scrofa A0A287AZA7 R-SSC-5696465 https://reactome.org/PathwayBrowser/#/R-SSC-5696465 USP45 deubiquitinates ERCC1 IEA Sus scrofa A0A287AZA7 R-SSC-5696534 https://reactome.org/PathwayBrowser/#/R-SSC-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Sus scrofa A0A287AZA7 R-SSC-5696547 https://reactome.org/PathwayBrowser/#/R-SSC-5696547 STAMBPL1 is a deubiquitinase IEA Sus scrofa A0A287AZA7 R-SSC-5696564 https://reactome.org/PathwayBrowser/#/R-SSC-5696564 USP25 deubiquitinates DDX58 IEA Sus scrofa A0A287AZA7 R-SSC-5696600 https://reactome.org/PathwayBrowser/#/R-SSC-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Sus scrofa A0A287AZA7 R-SSC-5696605 https://reactome.org/PathwayBrowser/#/R-SSC-5696605 USP12, USP26 deubiquitinate AR IEA Sus scrofa A0A287AZA7 R-SSC-5696627 https://reactome.org/PathwayBrowser/#/R-SSC-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Sus scrofa A0A287AZA7 R-SSC-5696655 https://reactome.org/PathwayBrowser/#/R-SSC-5696655 PARP1 or PARP2 PARylates DDB2 and autoPARylates IEA Sus scrofa A0A287AZA7 R-SSC-5696664 https://reactome.org/PathwayBrowser/#/R-SSC-5696664 PARP1 or PARP2 binds DDB2 at GG-NER site IEA Sus scrofa A0A287AZA7 R-SSC-5696670 https://reactome.org/PathwayBrowser/#/R-SSC-5696670 CHD1L is recruited to GG-NER site IEA Sus scrofa A0A287AZA7 R-SSC-5696872 https://reactome.org/PathwayBrowser/#/R-SSC-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Sus scrofa A0A287AZA7 R-SSC-5696914 https://reactome.org/PathwayBrowser/#/R-SSC-5696914 USP28 deubiquitinates CLSPN and MYC IEA Sus scrofa A0A287AZA7 R-SSC-5696945 https://reactome.org/PathwayBrowser/#/R-SSC-5696945 USP33 deubiquitinates CCP110,ARRB IEA Sus scrofa A0A287AZA7 R-SSC-5696947 https://reactome.org/PathwayBrowser/#/R-SSC-5696947 USP47 deubiquitinates POLB IEA Sus scrofa A0A287AZA7 R-SSC-5696958 https://reactome.org/PathwayBrowser/#/R-SSC-5696958 USP44 deubiquitinates CDC20 IEA Sus scrofa A0A287AZA7 R-SSC-5696960 https://reactome.org/PathwayBrowser/#/R-SSC-5696960 USP49 deubiquitinates H2B IEA Sus scrofa A0A287AZA7 R-SSC-5696968 https://reactome.org/PathwayBrowser/#/R-SSC-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Sus scrofa A0A287AZA7 R-SSC-5696997 https://reactome.org/PathwayBrowser/#/R-SSC-5696997 USP24 deubiquitinates DDB2 IEA Sus scrofa A0A287AZA7 R-SSC-5697009 https://reactome.org/PathwayBrowser/#/R-SSC-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Sus scrofa A0A287AZA7 R-SSC-6781764 https://reactome.org/PathwayBrowser/#/R-SSC-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Sus scrofa A0A287AZA7 R-SSC-6781779 https://reactome.org/PathwayBrowser/#/R-SSC-6781779 USP13 deubiquitinates BECN1,USP10 IEA Sus scrofa A0A287AZA7 R-SSC-6781814 https://reactome.org/PathwayBrowser/#/R-SSC-6781814 USP19 deubiquitinates RNF123 IEA Sus scrofa A0A287AZA7 R-SSC-6781867 https://reactome.org/PathwayBrowser/#/R-SSC-6781867 ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II IEA Sus scrofa A0A287AZA7 R-SSC-6781897 https://reactome.org/PathwayBrowser/#/R-SSC-6781897 USP11 deubiquitinates NFKBIA IEA Sus scrofa A0A287AZA7 R-SSC-6782004 https://reactome.org/PathwayBrowser/#/R-SSC-6782004 Assembly of the pre-incision complex in TC-NER IEA Sus scrofa A0A287AZA7 R-SSC-6782069 https://reactome.org/PathwayBrowser/#/R-SSC-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Sus scrofa A0A287AZA7 R-SSC-6782106 https://reactome.org/PathwayBrowser/#/R-SSC-6782106 USP10 deubiquitinates SNX3, CFTR IEA Sus scrofa A0A287AZA7 R-SSC-6782131 https://reactome.org/PathwayBrowser/#/R-SSC-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa A0A287AZA7 R-SSC-6782138 https://reactome.org/PathwayBrowser/#/R-SSC-6782138 ERCC5 and RPA bind TC-NER site IEA Sus scrofa A0A287AZA7 R-SSC-6782141 https://reactome.org/PathwayBrowser/#/R-SSC-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER IEA Sus scrofa A0A287AZA7 R-SSC-6782204 https://reactome.org/PathwayBrowser/#/R-SSC-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER IEA Sus scrofa A0A287AZA7 R-SSC-6782208 https://reactome.org/PathwayBrowser/#/R-SSC-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER IEA Sus scrofa A0A287AZA7 R-SSC-6782211 https://reactome.org/PathwayBrowser/#/R-SSC-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site IEA Sus scrofa A0A287AZA7 R-SSC-6782224 https://reactome.org/PathwayBrowser/#/R-SSC-6782224 3' incision by ERCC5 (XPG) in TC-NER IEA Sus scrofa A0A287AZA7 R-SSC-6782227 https://reactome.org/PathwayBrowser/#/R-SSC-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER IEA Sus scrofa A0A287AZA7 R-SSC-6782628 https://reactome.org/PathwayBrowser/#/R-SSC-6782628 USP8 deubiquitinates STAM2:HGS IEA Sus scrofa A0A287AZA7 R-SSC-6782820 https://reactome.org/PathwayBrowser/#/R-SSC-6782820 USP17 deubiquitinates SUDS3 IEA Sus scrofa A0A287AZA7 R-SSC-6782943 https://reactome.org/PathwayBrowser/#/R-SSC-6782943 UV-DDB ubiquitinates XPC IEA Sus scrofa A0A287AZA7 R-SSC-6783177 https://reactome.org/PathwayBrowser/#/R-SSC-6783177 USP21 deubiquitinates GATA3,IL33 IEA Sus scrofa A0A287AZA7 R-SSC-6785361 https://reactome.org/PathwayBrowser/#/R-SSC-6785361 Monoubiquitination of FANCD2:FANCI IEA Sus scrofa A0A287AZA7 R-SSC-6785732 https://reactome.org/PathwayBrowser/#/R-SSC-6785732 DNA nucleases bind monoubiquitinated ID2 complex IEA Sus scrofa A0A287AZA7 R-SSC-6785986 https://reactome.org/PathwayBrowser/#/R-SSC-6785986 DNA nucleases unhook the interstrand crosslink (ICL) IEA Sus scrofa A0A287AZA7 R-SSC-6786155 https://reactome.org/PathwayBrowser/#/R-SSC-6786155 POLN binds ICL-DNA IEA Sus scrofa A0A287AZA7 R-SSC-6786166 https://reactome.org/PathwayBrowser/#/R-SSC-6786166 Translesion synthesis across unhooked ICL by POLN IEA Sus scrofa A0A287AZA7 R-SSC-6786171 https://reactome.org/PathwayBrowser/#/R-SSC-6786171 FANCD2 deubiquitination by USP1:WDR48 IEA Sus scrofa A0A287AZA7 R-SSC-6790454 https://reactome.org/PathwayBrowser/#/R-SSC-6790454 SUMOylation of XPC IEA Sus scrofa A0A287AZA7 R-SSC-6798373 https://reactome.org/PathwayBrowser/#/R-SSC-6798373 MDM2 ubiquitinates DYRK2 IEA Sus scrofa A0A287AZA7 R-SSC-6804253 https://reactome.org/PathwayBrowser/#/R-SSC-6804253 MDM2 ubiquitinates JMY IEA Sus scrofa A0A287AZA7 R-SSC-6804441 https://reactome.org/PathwayBrowser/#/R-SSC-6804441 RNF34 or RFFL ubiquitinates phosphorylated TP53 IEA Sus scrofa A0A287AZA7 R-SSC-6804942 https://reactome.org/PathwayBrowser/#/R-SSC-6804942 MDM2 homodimers auto-ubiquitinate IEA Sus scrofa A0A287AZA7 R-SSC-6807106 https://reactome.org/PathwayBrowser/#/R-SSC-6807106 PTEN undergoes monoubiquitination IEA Sus scrofa A0A287AZA7 R-SSC-6807118 https://reactome.org/PathwayBrowser/#/R-SSC-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Sus scrofa A0A287AZA7 R-SSC-6807134 https://reactome.org/PathwayBrowser/#/R-SSC-6807134 NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN IEA Sus scrofa A0A287AZA7 R-SSC-6807206 https://reactome.org/PathwayBrowser/#/R-SSC-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Sus scrofa A0A287AZA7 R-SSC-68712 https://reactome.org/PathwayBrowser/#/R-SSC-68712 The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 IEA Sus scrofa A0A287AZA7 R-SSC-68825 https://reactome.org/PathwayBrowser/#/R-SSC-68825 Ubiquitinated geminin is degraded by the proteasome IEA Sus scrofa A0A287AZA7 R-SSC-68946 https://reactome.org/PathwayBrowser/#/R-SSC-68946 Phosphorylated Orc1 is ubiquitinated while still associated with chromatin IEA Sus scrofa A0A287AZA7 R-SSC-68948 https://reactome.org/PathwayBrowser/#/R-SSC-68948 Ubiquitinated Orc1 is degraded by the proteasome IEA Sus scrofa A0A287AZA7 R-SSC-69015 https://reactome.org/PathwayBrowser/#/R-SSC-69015 Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex IEA Sus scrofa A0A287AZA7 R-SSC-69016 https://reactome.org/PathwayBrowser/#/R-SSC-69016 Ubiquitinated Cdc6 is degraded by the proteasome IEA Sus scrofa A0A287AZA7 R-SSC-69600 https://reactome.org/PathwayBrowser/#/R-SSC-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Sus scrofa A0A287AZA7 R-SSC-72621 https://reactome.org/PathwayBrowser/#/R-SSC-72621 Ribosomal scanning IEA Sus scrofa A0A287AZA7 R-SSC-72671 https://reactome.org/PathwayBrowser/#/R-SSC-72671 eIF5B:GTP is hydrolyzed and released IEA Sus scrofa A0A287AZA7 R-SSC-72672 https://reactome.org/PathwayBrowser/#/R-SSC-72672 The 60S subunit joins the translation initiation complex IEA Sus scrofa A0A287AZA7 R-SSC-72673 https://reactome.org/PathwayBrowser/#/R-SSC-72673 Release of 40S and 60S subunits from the 80S ribosome IEA Sus scrofa A0A287AZA7 R-SSC-72676 https://reactome.org/PathwayBrowser/#/R-SSC-72676 eIF3 and eIF1A bind to the 40S subunit IEA Sus scrofa A0A287AZA7 R-SSC-72691 https://reactome.org/PathwayBrowser/#/R-SSC-72691 Formation of the 43S pre-initiation complex IEA Sus scrofa A0A287AZA7 R-SSC-72697 https://reactome.org/PathwayBrowser/#/R-SSC-72697 Start codon recognition IEA Sus scrofa A0A287AZA7 R-SSC-75825 https://reactome.org/PathwayBrowser/#/R-SSC-75825 Proteasome mediated degradation of Cyclin D1 IEA Sus scrofa A0A287AZA7 R-SSC-870437 https://reactome.org/PathwayBrowser/#/R-SSC-870437 USP9X (FAM) deubiquitinates SMAD4 IEA Sus scrofa A0A287AZA7 R-SSC-870449 https://reactome.org/PathwayBrowser/#/R-SSC-870449 TRIM33 monoubiquitinates SMAD4 IEA Sus scrofa A0A287AZA7 R-SSC-8848829 https://reactome.org/PathwayBrowser/#/R-SSC-8848829 CBL autoubiquitinates IEA Sus scrofa A0A287AZA7 R-SSC-8850594 https://reactome.org/PathwayBrowser/#/R-SSC-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Sus scrofa A0A287AZA7 R-SSC-8850992 https://reactome.org/PathwayBrowser/#/R-SSC-8850992 Proteasome degrades polyubiquitinated PTEN IEA Sus scrofa A0A287AZA7 R-SSC-8851011 https://reactome.org/PathwayBrowser/#/R-SSC-8851011 TRIM27 polyubiquitinates PTEN IEA Sus scrofa A0A287AZA7 R-SSC-8852127 https://reactome.org/PathwayBrowser/#/R-SSC-8852127 UBA6 conjugates ubiquitin to cytosolic E2 enzymes IEA Sus scrofa A0A287AZA7 R-SSC-8852128 https://reactome.org/PathwayBrowser/#/R-SSC-8852128 UBA1 adenylates ubiquitin in the nucleoplasm IEA Sus scrofa A0A287AZA7 R-SSC-8852129 https://reactome.org/PathwayBrowser/#/R-SSC-8852129 UBA1 conjugates ubiquitin to cytosolic E2 enzymes IEA Sus scrofa A0A287AZA7 R-SSC-8852130 https://reactome.org/PathwayBrowser/#/R-SSC-8852130 UBA1 conjugates ubiquitin to nuclear E2 enzymes IEA Sus scrofa A0A287AZA7 R-SSC-8852131 https://reactome.org/PathwayBrowser/#/R-SSC-8852131 Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus IEA Sus scrofa A0A287AZA7 R-SSC-8852132 https://reactome.org/PathwayBrowser/#/R-SSC-8852132 Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol IEA Sus scrofa A0A287AZA7 R-SSC-8852133 https://reactome.org/PathwayBrowser/#/R-SSC-8852133 UBA1 conjugates ubiquitin to UBA1 in the cytosol IEA Sus scrofa A0A287AZA7 R-SSC-8852134 https://reactome.org/PathwayBrowser/#/R-SSC-8852134 UBA1 adenylates ubiquitin in the cytosol IEA Sus scrofa A0A287AZA7 R-SSC-8852136 https://reactome.org/PathwayBrowser/#/R-SSC-8852136 UBA1 conjugates ubiquitin to UBA1 in the nucleus IEA Sus scrofa A0A287AZA7 R-SSC-8852354 https://reactome.org/PathwayBrowser/#/R-SSC-8852354 GTSE1 facilitates proteasome-mediated degradation of TP53 IEA Sus scrofa A0A287AZA7 R-SSC-8853379 https://reactome.org/PathwayBrowser/#/R-SSC-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Sus scrofa A0A287AZA7 R-SSC-8853503 https://reactome.org/PathwayBrowser/#/R-SSC-8853503 UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin IEA Sus scrofa A0A287AZA7 R-SSC-8854041 https://reactome.org/PathwayBrowser/#/R-SSC-8854041 SCF-FBXL7 ubiquitinates AURKA IEA Sus scrofa A0A287AZA7 R-SSC-8854044 https://reactome.org/PathwayBrowser/#/R-SSC-8854044 Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 IEA Sus scrofa A0A287AZA7 R-SSC-8854051 https://reactome.org/PathwayBrowser/#/R-SSC-8854051 SCF-FBXL18 ubiquitinates FBXL7 IEA Sus scrofa A0A287AZA7 R-SSC-8854071 https://reactome.org/PathwayBrowser/#/R-SSC-8854071 Proteasome-mediated degradation of PolyUb-FBXL7 IEA Sus scrofa A0A287AZA7 R-SSC-8854628 https://reactome.org/PathwayBrowser/#/R-SSC-8854628 MYLIP dimer ubiquitinates VLDLR on Lys-839 IEA Sus scrofa A0A287AZA7 R-SSC-8862184 https://reactome.org/PathwayBrowser/#/R-SSC-8862184 USP48 cleaves polyubiquitin IEA Sus scrofa A0A287AZA7 R-SSC-8865182 https://reactome.org/PathwayBrowser/#/R-SSC-8865182 OTUD7A hydrolyses K11diUb IEA Sus scrofa A0A287AZA7 R-SSC-8866279 https://reactome.org/PathwayBrowser/#/R-SSC-8866279 Epsin family proteins bind ubiquitinated cargo IEA Sus scrofa A0A287AZA7 R-SSC-8866542 https://reactome.org/PathwayBrowser/#/R-SSC-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Sus scrofa A0A287AZA7 R-SSC-8866546 https://reactome.org/PathwayBrowser/#/R-SSC-8866546 RNF5 and RNF185 ubiquitinate misfolded CFTR IEA Sus scrofa A0A287AZA7 R-SSC-8866553 https://reactome.org/PathwayBrowser/#/R-SSC-8866553 misfolded CFTR is degraded by the 26S proteasome IEA Sus scrofa A0A287AZA7 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A287AZA7 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A287AZA7 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A287AZA7 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A287AZA7 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A287AZA7 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287AZA7 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287AZA7 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287AZA7 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287AZA7 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287AZA7 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287AZA7 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287AZA7 R-SSC-8869456 https://reactome.org/PathwayBrowser/#/R-SSC-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Sus scrofa A0A287AZA7 R-SSC-8869506 https://reactome.org/PathwayBrowser/#/R-SSC-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Sus scrofa A0A287AZA7 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287AZA7 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287AZA7 R-SSC-8875183 https://reactome.org/PathwayBrowser/#/R-SSC-8875183 CBL monoubiquitinates activated MET IEA Sus scrofa A0A287AZA7 R-SSC-8875443 https://reactome.org/PathwayBrowser/#/R-SSC-8875443 USP8 deubiquitinates LRIG1 IEA Sus scrofa A0A287AZA7 R-SSC-8932355 https://reactome.org/PathwayBrowser/#/R-SSC-8932355 26S proteasome degrades Ub-NFE2L2 IEA Sus scrofa A0A287AZA7 R-SSC-8938770 https://reactome.org/PathwayBrowser/#/R-SSC-8938770 RNF144A binds PRKDC and Ubiquitin:UBE2L3 IEA Sus scrofa A0A287AZA7 R-SSC-8938773 https://reactome.org/PathwayBrowser/#/R-SSC-8938773 RNF144A polyubiquitinates PRKDC IEA Sus scrofa A0A287AZA7 R-SSC-8938815 https://reactome.org/PathwayBrowser/#/R-SSC-8938815 RNF152 polyubiquitinates RRAGA IEA Sus scrofa A0A287AZA7 R-SSC-8938829 https://reactome.org/PathwayBrowser/#/R-SSC-8938829 RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 IEA Sus scrofa A0A287AZA7 R-SSC-8939323 https://reactome.org/PathwayBrowser/#/R-SSC-8939323 RNF181 binds BCL10 and Ubiquitin:E2 IEA Sus scrofa A0A287AZA7 R-SSC-8939335 https://reactome.org/PathwayBrowser/#/R-SSC-8939335 RNF181 polyubiquinates BCL10 IEA Sus scrofa A0A287AZA7 R-SSC-8939706 https://reactome.org/PathwayBrowser/#/R-SSC-8939706 SCF(SKP2) polyubiquitinates RUNX2 IEA Sus scrofa A0A287AZA7 R-SSC-8939801 https://reactome.org/PathwayBrowser/#/R-SSC-8939801 26S proteasome degrades PolyUb-RUNX2 IEA Sus scrofa A0A287AZA7 R-SSC-8942099 https://reactome.org/PathwayBrowser/#/R-SSC-8942099 RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B IEA Sus scrofa A0A287AZA7 R-SSC-8942101 https://reactome.org/PathwayBrowser/#/R-SSC-8942101 RNF20:RNF40 monoubiquitinates Histone H2B IEA Sus scrofa A0A287AZA7 R-SSC-8948015 https://reactome.org/PathwayBrowser/#/R-SSC-8948015 hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb IEA Sus scrofa A0A287AZA7 R-SSC-8948063 https://reactome.org/PathwayBrowser/#/R-SSC-8948063 hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1 IEA Sus scrofa A0A287AZA7 R-SSC-8948709 https://reactome.org/PathwayBrowser/#/R-SSC-8948709 DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 IEA Sus scrofa A0A287AZA7 R-SSC-8948775 https://reactome.org/PathwayBrowser/#/R-SSC-8948775 MKRN1 polyubiquitinates PTEN IEA Sus scrofa A0A287AZA7 R-SSC-8948832 https://reactome.org/PathwayBrowser/#/R-SSC-8948832 RNF146 polyubiquitinates PARylated PTEN IEA Sus scrofa A0A287AZA7 R-SSC-8952382 https://reactome.org/PathwayBrowser/#/R-SSC-8952382 MDM2 polyubiquitinates RUNX3 IEA Sus scrofa A0A287AZA7 R-SSC-8952408 https://reactome.org/PathwayBrowser/#/R-SSC-8952408 Polyubiquitinated RUNX3 is degraded by the proteasome IEA Sus scrofa A0A287AZA7 R-SSC-8952419 https://reactome.org/PathwayBrowser/#/R-SSC-8952419 SMURFs ubiquitinate RUNX3 IEA Sus scrofa A0A287AZA7 R-SSC-8953917 https://reactome.org/PathwayBrowser/#/R-SSC-8953917 PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 IEA Sus scrofa A0A287AZA7 R-SSC-8953946 https://reactome.org/PathwayBrowser/#/R-SSC-8953946 PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 IEA Sus scrofa A0A287AZA7 R-SSC-8956026 https://reactome.org/PathwayBrowser/#/R-SSC-8956026 CUL9:RBX1 ubiquitinates BIRC5 IEA Sus scrofa A0A287AZA7 R-SSC-8956106 https://reactome.org/PathwayBrowser/#/R-SSC-8956106 VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha IEA Sus scrofa A0A287AZA7 R-SSC-8956684 https://reactome.org/PathwayBrowser/#/R-SSC-8956684 ITCH polyubiquitinates TP73 IEA Sus scrofa A0A287AZA7 R-SSC-8957265 https://reactome.org/PathwayBrowser/#/R-SSC-8957265 26S proteasome degrades TP73 polyubiquitinated by ITCH IEA Sus scrofa A0A287AZA7 R-SSC-9009308 https://reactome.org/PathwayBrowser/#/R-SSC-9009308 STUB1 polyubiquitinates RUNX2 IEA Sus scrofa A0A287AZA7 R-SSC-9033485 https://reactome.org/PathwayBrowser/#/R-SSC-9033485 PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 IEA Sus scrofa A0A287AZA7 R-SSC-9033491 https://reactome.org/PathwayBrowser/#/R-SSC-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Sus scrofa A0A287AZA7 R-SSC-9033499 https://reactome.org/PathwayBrowser/#/R-SSC-9033499 PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol IEA Sus scrofa A0A287AZA7 R-SSC-9033509 https://reactome.org/PathwayBrowser/#/R-SSC-9033509 USP9X binds Ub:PEX5L IEA Sus scrofa A0A287AZA7 R-SSC-9033516 https://reactome.org/PathwayBrowser/#/R-SSC-9033516 PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Sus scrofa A0A287AZA7 R-SSC-9033527 https://reactome.org/PathwayBrowser/#/R-SSC-9033527 PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 IEA Sus scrofa A0A287AZA7 R-SSC-9033533 https://reactome.org/PathwayBrowser/#/R-SSC-9033533 PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 IEA Sus scrofa A0A287AZA7 R-SSC-909719 https://reactome.org/PathwayBrowser/#/R-SSC-909719 Recruitment of STAT2 to p-IFNAR1 IEA Sus scrofa A0A287AZA7 R-SSC-912627 https://reactome.org/PathwayBrowser/#/R-SSC-912627 CBL ubiquitinates PI3K IEA Sus scrofa A0A287AZA7 R-SSC-917693 https://reactome.org/PathwayBrowser/#/R-SSC-917693 ESCRT Disassembly IEA Sus scrofa A0A287AZA7 R-SSC-917696 https://reactome.org/PathwayBrowser/#/R-SSC-917696 Cargo Sequestration IEA Sus scrofa A0A287AZA7 R-SSC-917700 https://reactome.org/PathwayBrowser/#/R-SSC-917700 MVB Vesicle Formation IEA Sus scrofa A0A287AZA7 R-SSC-917730 https://reactome.org/PathwayBrowser/#/R-SSC-917730 Cargo Recognition And Sorting IEA Sus scrofa A0A287AZA7 R-SSC-927789 https://reactome.org/PathwayBrowser/#/R-SSC-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex IEA Sus scrofa A0A287AZA7 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A287AZA7 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A287AZA7 R-SSC-927836 https://reactome.org/PathwayBrowser/#/R-SSC-927836 SMG6 hydrolyzes mRNA with premature termination codon IEA Sus scrofa A0A287AZA7 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A287AZA7 R-SSC-934604 https://reactome.org/PathwayBrowser/#/R-SSC-934604 Phosphorylated SPRY2 is ubiquitinated by CBL IEA Sus scrofa A0A287AZA7 R-SSC-936390 https://reactome.org/PathwayBrowser/#/R-SSC-936390 CYLD mediated deubiquitination of DDX58 (RIG-I) IEA Sus scrofa A0A287AZA7 R-SSC-936942 https://reactome.org/PathwayBrowser/#/R-SSC-936942 Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 IEA Sus scrofa A0A287AZA7 R-SSC-936947 https://reactome.org/PathwayBrowser/#/R-SSC-936947 Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex IEA Sus scrofa A0A287AZA7 R-SSC-936951 https://reactome.org/PathwayBrowser/#/R-SSC-936951 Activation of TAK1 complex bound to activated TLR4 complex IEA Sus scrofa A0A287AZA7 R-SSC-936952 https://reactome.org/PathwayBrowser/#/R-SSC-936952 Auto ubiquitination of TRAF6 bound to the activated TLR4 complex IEA Sus scrofa A0A287AZA7 R-SSC-936960 https://reactome.org/PathwayBrowser/#/R-SSC-936960 Activated TRAF6:p-IRAK2 interacts with TAK1 complex IEA Sus scrofa A0A287AZA7 R-SSC-936986 https://reactome.org/PathwayBrowser/#/R-SSC-936986 Activated TRAF6 synthesizes unanchored polyubiquitin chains IEA Sus scrofa A0A287AZA7 R-SSC-936991 https://reactome.org/PathwayBrowser/#/R-SSC-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 IEA Sus scrofa A0A287AZA7 R-SSC-937050 https://reactome.org/PathwayBrowser/#/R-SSC-937050 Pellino ubiquitinates hp-IRAK1 IEA Sus scrofa A0A287AZA7 R-SSC-937075 https://reactome.org/PathwayBrowser/#/R-SSC-937075 Phosphorylated TAK1 leaves activated TLR receptor complex IEA Sus scrofa A0A287AZA7 R-SSC-9641096 https://reactome.org/PathwayBrowser/#/R-SSC-9641096 Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub IEA Sus scrofa A0A287AZA7 R-SSC-9641111 https://reactome.org/PathwayBrowser/#/R-SSC-9641111 Parkin transfers Ub to misfolded proteins IEA Sus scrofa A0A287AZA7 R-SSC-9641127 https://reactome.org/PathwayBrowser/#/R-SSC-9641127 Ub:misfolded proteins polymerize to PolyUb:misfolded proteins IEA Sus scrofa A0A287AZA7 R-SSC-9645394 https://reactome.org/PathwayBrowser/#/R-SSC-9645394 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation IEA Sus scrofa A0A287AZA7 R-SSC-9645406 https://reactome.org/PathwayBrowser/#/R-SSC-9645406 ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) IEA Sus scrofa A0A287AZA7 R-SSC-9645414 https://reactome.org/PathwayBrowser/#/R-SSC-9645414 Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer IEA Sus scrofa A0A287AZA7 R-SSC-9645442 https://reactome.org/PathwayBrowser/#/R-SSC-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex IEA Sus scrofa A0A287AZA7 R-SSC-9646348 https://reactome.org/PathwayBrowser/#/R-SSC-9646348 PolyUb-Misfolded Proteins:HDAC6 bind dynein motor IEA Sus scrofa A0A287AZA7 R-SSC-9646679 https://reactome.org/PathwayBrowser/#/R-SSC-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Sus scrofa A0A287AZA7 R-SSC-9646685 https://reactome.org/PathwayBrowser/#/R-SSC-9646685 Aggresome dissociates from dynein and microtubule IEA Sus scrofa A0A287AZA7 R-SSC-9653514 https://reactome.org/PathwayBrowser/#/R-SSC-9653514 USP17L2 deubiquitinates RCE1 IEA Sus scrofa A0A287AZA7 R-SSC-9664888 https://reactome.org/PathwayBrowser/#/R-SSC-9664888 ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 IEA Sus scrofa A0A287AZA7 R-SSC-9674127 https://reactome.org/PathwayBrowser/#/R-SSC-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Sus scrofa A0A287AZA7 R-SSC-9684118 https://reactome.org/PathwayBrowser/#/R-SSC-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER IEA Sus scrofa A0A287AZA7 R-SSC-9686920 https://reactome.org/PathwayBrowser/#/R-SSC-9686920 PELI1 ubiquitinates RIPK3 at K363 IEA Sus scrofa A0A287AZA7 R-SSC-9686969 https://reactome.org/PathwayBrowser/#/R-SSC-9686969 APC/C:Cdh1 polyubiquitinates SKP2 IEA Sus scrofa A0A287AZA7 R-SSC-9688831 https://reactome.org/PathwayBrowser/#/R-SSC-9688831 STUB1 ubiquitinates RIPK3 at K55, K363 IEA Sus scrofa A0A287AZA7 R-SSC-9701000 https://reactome.org/PathwayBrowser/#/R-SSC-9701000 BRCA1:BARD1 heterodimer autoubiquitinates IEA Sus scrofa A0A287AZA7 R-SSC-9706354 https://reactome.org/PathwayBrowser/#/R-SSC-9706354 Ubiquitination of FLT3 IEA Sus scrofa A0A287AZA7 R-SSC-9708517 https://reactome.org/PathwayBrowser/#/R-SSC-9708517 FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2)) IEA Sus scrofa A0A287AZA7 R-SSC-9750942 https://reactome.org/PathwayBrowser/#/R-SSC-9750942 USP14 deubiquitinates NLRC5 IEA Sus scrofa A0A287AZA7 R-SSC-9750946 https://reactome.org/PathwayBrowser/#/R-SSC-9750946 TRAF2,6 ubiquitinates NLRC5 IEA Sus scrofa A0A287AZA7 R-SSC-975097 https://reactome.org/PathwayBrowser/#/R-SSC-975097 Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation IEA Sus scrofa A0A287AZA7 R-SSC-975103 https://reactome.org/PathwayBrowser/#/R-SSC-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation IEA Sus scrofa A0A287AZA7 R-SSC-975122 https://reactome.org/PathwayBrowser/#/R-SSC-975122 Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
IEA Sus scrofa A0A287AZA7 R-SSC-975147 https://reactome.org/PathwayBrowser/#/R-SSC-975147 Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane IEA Sus scrofa A0A287AZA7 R-SSC-9755303 https://reactome.org/PathwayBrowser/#/R-SSC-9755303 26S proteasome degrades HIFalpha IEA Sus scrofa A0A287AZA7 R-SSC-9755304 https://reactome.org/PathwayBrowser/#/R-SSC-9755304 MUL1 ubiquitinates UBXN7 IEA Sus scrofa A0A287AZA7 R-SSC-9755306 https://reactome.org/PathwayBrowser/#/R-SSC-9755306 ub UBXN7 is degraded by the 26S proteasome IEA Sus scrofa A0A287AZA7 R-SSC-9755505 https://reactome.org/PathwayBrowser/#/R-SSC-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Sus scrofa A0A287AZA7 R-SSC-9758604 https://reactome.org/PathwayBrowser/#/R-SSC-9758604 Ubiquitination of IKBKG by TRAF6 IEA Sus scrofa A0A287AZA7 R-SSC-9759154 https://reactome.org/PathwayBrowser/#/R-SSC-9759154 TRIM21 ubiquitinates SQSTM1 IEA Sus scrofa A0A287AZA7 R-SSC-9759172 https://reactome.org/PathwayBrowser/#/R-SSC-9759172 KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer IEA Sus scrofa A0A287AZA7 R-SSC-9762091 https://reactome.org/PathwayBrowser/#/R-SSC-9762091 NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 IEA Sus scrofa A0A287AZA7 R-SSC-9762096 https://reactome.org/PathwayBrowser/#/R-SSC-9762096 Ub,pS335,S338,T NFE2L2 is degraded IEA Sus scrofa A0A287AZA7 R-SSC-9766645 https://reactome.org/PathwayBrowser/#/R-SSC-9766645 CUL3:RBX1 ubiquitinates KEAP1 IEA Sus scrofa A0A287AZA7 R-SSC-9793444 https://reactome.org/PathwayBrowser/#/R-SSC-9793444 ITCH polyubiquitinates MLKL at K50 IEA Sus scrofa A0A287AZA7 R-SSC-9793451 https://reactome.org/PathwayBrowser/#/R-SSC-9793451 MLKL binds ITCH IEA Sus scrofa A0A287AZA7 R-SSC-9793679 https://reactome.org/PathwayBrowser/#/R-SSC-9793679 LUBAC ubiquitinates RIPK1 at K627 IEA Sus scrofa A0A287AZA7 R-SSC-9796342 https://reactome.org/PathwayBrowser/#/R-SSC-9796342 MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 IEA Sus scrofa A0A287AZA7 R-SSC-9796346 https://reactome.org/PathwayBrowser/#/R-SSC-9796346 MIB2 ubiquitinates RIPK1 at K377, K604, K634 IEA Sus scrofa A0A287AZA7 R-SSC-9796368 https://reactome.org/PathwayBrowser/#/R-SSC-9796368 RIPK1 binds STUB1 IEA Sus scrofa A0A287AZA7 R-SSC-9796387 https://reactome.org/PathwayBrowser/#/R-SSC-9796387 STUB1 ubiquitinates RIPK1 at K571, K604, K627 IEA Sus scrofa A0A287AZA7 R-SSC-9796617 https://reactome.org/PathwayBrowser/#/R-SSC-9796617 MIB2 binds CFLAR IEA Sus scrofa A0A287AZA7 R-SSC-9796626 https://reactome.org/PathwayBrowser/#/R-SSC-9796626 MIB2 ubiquitinates CFLAR IEA Sus scrofa A0A287AZA7 R-SSC-9815507 https://reactome.org/PathwayBrowser/#/R-SSC-9815507 MIB2 ubiquitinates CYLD at K338, K530 IEA Sus scrofa A0A287AZA7 R-SSC-9815510 https://reactome.org/PathwayBrowser/#/R-SSC-9815510 MIB2 binds CYLD IEA Sus scrofa A0A287AZA7 R-SSC-9817362 https://reactome.org/PathwayBrowser/#/R-SSC-9817362 SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex IEA Sus scrofa A0A287AZA7 R-SSC-9817400 https://reactome.org/PathwayBrowser/#/R-SSC-9817400 CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex IEA Sus scrofa A0A287AZA7 R-SSC-9818975 https://reactome.org/PathwayBrowser/#/R-SSC-9818975 CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex IEA Sus scrofa A0A287AZA7 R-SSC-9823904 https://reactome.org/PathwayBrowser/#/R-SSC-9823904 TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 IEA Sus scrofa A0A287AZA7 R-SSC-9823939 https://reactome.org/PathwayBrowser/#/R-SSC-9823939 IKKε (IKBKE) is ubiquitinated within the activated TLR4 IEA Sus scrofa A0A287AZA7 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287AZA7 R-SSC-983150 https://reactome.org/PathwayBrowser/#/R-SSC-983150 Proteasomal cleavage of substrate IEA Sus scrofa A0A287AZA7 R-SSC-983152 https://reactome.org/PathwayBrowser/#/R-SSC-983152 Transfer of ubiquitin from E1 to E2 IEA Sus scrofa A0A287AZA7 R-SSC-983153 https://reactome.org/PathwayBrowser/#/R-SSC-983153 E1 mediated ubiquitin activation IEA Sus scrofa A0A287AZA7 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287AZA7 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287AZA7 R-SSC-9861563 https://reactome.org/PathwayBrowser/#/R-SSC-9861563 CTLH E3 ligase ubiquitinates LDHA IEA Sus scrofa A0A287AZA7 R-SSC-9861640 https://reactome.org/PathwayBrowser/#/R-SSC-9861640 CTLH E3 ligase ubiquitinates PKM-1 IEA Sus scrofa A0A287AZA7 R-SSC-9934893 https://reactome.org/PathwayBrowser/#/R-SSC-9934893 Proteolysis of K48polyUb-K,p-S-PER1,2,3 IEA Sus scrofa A0A287AZB6 R-SSC-429798 https://reactome.org/PathwayBrowser/#/R-SSC-429798 SGMS1 transfers phosphocholine onto ceramide IEA Sus scrofa A0A287AZB9 R-SSC-5668714 https://reactome.org/PathwayBrowser/#/R-SSC-5668714 RAC1:GTP binds NOX1 complex IEA Sus scrofa A0A287AZB9 R-SSC-5668718 https://reactome.org/PathwayBrowser/#/R-SSC-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa A0A287AZB9 R-SSC-5668731 https://reactome.org/PathwayBrowser/#/R-SSC-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa A0A287AZB9 R-SSC-5668735 https://reactome.org/PathwayBrowser/#/R-SSC-5668735 RAC1:GTP binds NOX3 complex IEA Sus scrofa A0A287AZB9 R-SSC-9013145 https://reactome.org/PathwayBrowser/#/R-SSC-9013145 RAC1 binds effectors at the plasma membrane IEA Sus scrofa A0A287AZB9 R-SSC-9018808 https://reactome.org/PathwayBrowser/#/R-SSC-9018808 RAC3 binds effectors at the plasma membrane IEA Sus scrofa A0A287AZD5 R-SSC-1433374 https://reactome.org/PathwayBrowser/#/R-SSC-1433374 Processing of SCF isoform 1 IEA Sus scrofa A0A287AZD5 R-SSC-1454757 https://reactome.org/PathwayBrowser/#/R-SSC-1454757 Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 IEA Sus scrofa A0A287AZD5 R-SSC-1454781 https://reactome.org/PathwayBrowser/#/R-SSC-1454781 MMP1,3,13 (2, 7-12, 19) binding by Alpha-2 macroglubulin IEA Sus scrofa A0A287AZD5 R-SSC-1454791 https://reactome.org/PathwayBrowser/#/R-SSC-1454791 MMP2, MMP7, MMP9 bind CD44 IEA Sus scrofa A0A287AZD5 R-SSC-1474213 https://reactome.org/PathwayBrowser/#/R-SSC-1474213 Collagen type III degradation by MMP1,8,9,13 IEA Sus scrofa A0A287AZD5 R-SSC-1564112 https://reactome.org/PathwayBrowser/#/R-SSC-1564112 Collagen type VI degradation by MMP2,9,11 IEA Sus scrofa A0A287AZD5 R-SSC-1564142 https://reactome.org/PathwayBrowser/#/R-SSC-1564142 Collagen type IV degradation by MMP2,3,4,9,10,12 IEA Sus scrofa A0A287AZD5 R-SSC-1564164 https://reactome.org/PathwayBrowser/#/R-SSC-1564164 Collagen type V degradation by MMP2,9,10 IEA Sus scrofa A0A287AZD5 R-SSC-1566962 https://reactome.org/PathwayBrowser/#/R-SSC-1566962 Elastin degradation by elastin-degrading extracellular proteinases IEA Sus scrofa A0A287AZD5 R-SSC-1592436 https://reactome.org/PathwayBrowser/#/R-SSC-1592436 Initial activation of proMMP9 by MMPs IEA Sus scrofa A0A287AZD5 R-SSC-1602454 https://reactome.org/PathwayBrowser/#/R-SSC-1602454 proMMP9 binds TIMP1 IEA Sus scrofa A0A287AZD5 R-SSC-1604690 https://reactome.org/PathwayBrowser/#/R-SSC-1604690 Activation of MMP9 intermediate form by MMPs IEA Sus scrofa A0A287AZD5 R-SSC-1604722 https://reactome.org/PathwayBrowser/#/R-SSC-1604722 Activation of proMMP9 by proteases IEA Sus scrofa A0A287AZD5 R-SSC-2168923 https://reactome.org/PathwayBrowser/#/R-SSC-2168923 Collagen type XVIII endostatin release IEA Sus scrofa A0A287AZD5 R-SSC-2213200 https://reactome.org/PathwayBrowser/#/R-SSC-2213200 Release of endostatin-like peptides IEA Sus scrofa A0A287AZD5 R-SSC-2485148 https://reactome.org/PathwayBrowser/#/R-SSC-2485148 Fibrillin 1, 2,(3) degradation by MMP2, 9, 12 and 13 IEA Sus scrofa A0A287AZD5 R-SSC-3827958 https://reactome.org/PathwayBrowser/#/R-SSC-3827958 E-cadherin degradation by MMP9, KLK7 IEA Sus scrofa A0A287AZD5 R-SSC-3928657 https://reactome.org/PathwayBrowser/#/R-SSC-3928657 MMP2,9 cleave EPHB IEA Sus scrofa A0A287AZD5 R-SSC-6798745 https://reactome.org/PathwayBrowser/#/R-SSC-6798745 Exocytosis of tertiary granule lumen proteins IEA Sus scrofa A0A287AZD5 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287AZD5 R-SSC-8943959 https://reactome.org/PathwayBrowser/#/R-SSC-8943959 MMP2, MMP9 cleave SCUBE3 IEA Sus scrofa A0A287AZD5 R-SSC-9624272 https://reactome.org/PathwayBrowser/#/R-SSC-9624272 MMPs cleave HB-EGF IEA Sus scrofa A0A287AZE1 R-SSC-1482533 https://reactome.org/PathwayBrowser/#/R-SSC-1482533 2-acyl LPC is acylated to PC by LPCAT IEA Sus scrofa A0A287AZE1 R-SSC-1482539 https://reactome.org/PathwayBrowser/#/R-SSC-1482539 1-acyl LPG is acylated to PG by LPGAT IEA Sus scrofa A0A287AZE1 R-SSC-1482547 https://reactome.org/PathwayBrowser/#/R-SSC-1482547 1-acyl LPC is acylated to PC by LPCAT IEA Sus scrofa A0A287AZE1 R-SSC-1482635 https://reactome.org/PathwayBrowser/#/R-SSC-1482635 2-acyl LPG is acylated to PG by LPGAT IEA Sus scrofa A0A287AZE1 R-SSC-1482636 https://reactome.org/PathwayBrowser/#/R-SSC-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Sus scrofa A0A287AZE1 R-SSC-1482646 https://reactome.org/PathwayBrowser/#/R-SSC-1482646 2-acyl LPE is acylated to PE by LPEAT IEA Sus scrofa A0A287AZE1 R-SSC-1482667 https://reactome.org/PathwayBrowser/#/R-SSC-1482667 1-acyl LPE is acylated to PE by LPEAT IEA Sus scrofa A0A287AZE1 R-SSC-1482691 https://reactome.org/PathwayBrowser/#/R-SSC-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Sus scrofa A0A287AZE1 R-SSC-75885 https://reactome.org/PathwayBrowser/#/R-SSC-75885 1-acyl LPA is acylated to PA by AGPAT (LPAAT) IEA Sus scrofa A0A287AZF2 R-SSC-1454757 https://reactome.org/PathwayBrowser/#/R-SSC-1454757 Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 IEA Sus scrofa A0A287AZF2 R-SSC-1564142 https://reactome.org/PathwayBrowser/#/R-SSC-1564142 Collagen type IV degradation by MMP2,3,4,9,10,12 IEA Sus scrofa A0A287AZF2 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa A0A287AZF2 R-SSC-1981104 https://reactome.org/PathwayBrowser/#/R-SSC-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Sus scrofa A0A287AZF2 R-SSC-1981120 https://reactome.org/PathwayBrowser/#/R-SSC-1981120 Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 IEA Sus scrofa A0A287AZF2 R-SSC-1981128 https://reactome.org/PathwayBrowser/#/R-SSC-1981128 Galactosylation of collagen propeptide hydroxylysines by PLOD3 IEA Sus scrofa A0A287AZF2 R-SSC-1981157 https://reactome.org/PathwayBrowser/#/R-SSC-1981157 Glucosylation of collagen propeptide hydroxylysines IEA Sus scrofa A0A287AZF2 R-SSC-2002460 https://reactome.org/PathwayBrowser/#/R-SSC-2002460 P4HB binds Collagen chains IEA Sus scrofa A0A287AZF2 R-SSC-2089971 https://reactome.org/PathwayBrowser/#/R-SSC-2089971 Secretion of collagens IEA Sus scrofa A0A287AZF2 R-SSC-2213207 https://reactome.org/PathwayBrowser/#/R-SSC-2213207 Formation of collagen networks IEA Sus scrofa A0A287AZF2 R-SSC-2327695 https://reactome.org/PathwayBrowser/#/R-SSC-2327695 Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 IEA Sus scrofa A0A287AZF2 R-SSC-2327733 https://reactome.org/PathwayBrowser/#/R-SSC-2327733 FN1 binds Collagen types I-V, VII IEA Sus scrofa A0A287AZF2 R-SSC-2327738 https://reactome.org/PathwayBrowser/#/R-SSC-2327738 DDR1 binds collagen type I, II, III, IV, V, XI fibrils IEA Sus scrofa A0A287AZF2 R-SSC-2426450 https://reactome.org/PathwayBrowser/#/R-SSC-2426450 Laminins:Nidogens binds collagen type IV networks IEA Sus scrofa A0A287AZF2 R-SSC-2559639 https://reactome.org/PathwayBrowser/#/R-SSC-2559639 Collagen type IV sulfilimine cross-linking by peroxidasin IEA Sus scrofa A0A287AZF2 R-SSC-382054 https://reactome.org/PathwayBrowser/#/R-SSC-382054 PDGF binds to extracellular matrix proteins IEA Sus scrofa A0A287AZF2 R-SSC-4088218 https://reactome.org/PathwayBrowser/#/R-SSC-4088218 Tetrastatin binds integrin alphaVbeta3 IEA Sus scrofa A0A287AZF2 R-SSC-8944265 https://reactome.org/PathwayBrowser/#/R-SSC-8944265 Association of procollagen type IV IEA Sus scrofa A0A287AZF2 R-SSC-8948219 https://reactome.org/PathwayBrowser/#/R-SSC-8948219 PLOD3 binds Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A287AZF2 R-SSC-8948222 https://reactome.org/PathwayBrowser/#/R-SSC-8948222 PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287AZF2 R-SSC-8948224 https://reactome.org/PathwayBrowser/#/R-SSC-8948224 PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287AZF2 R-SSC-8948228 https://reactome.org/PathwayBrowser/#/R-SSC-8948228 COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides IEA Sus scrofa A0A287AZF2 R-SSC-8948231 https://reactome.org/PathwayBrowser/#/R-SSC-8948231 COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates IEA Sus scrofa A0A287AZF2 R-SSC-8948232 https://reactome.org/PathwayBrowser/#/R-SSC-8948232 Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases IEA Sus scrofa A0A287AZF2 R-SSC-8948234 https://reactome.org/PathwayBrowser/#/R-SSC-8948234 P4HB:4-Hyp collagen propeptides dissociates IEA Sus scrofa A0A287AZF3 R-SSC-9770141 https://reactome.org/PathwayBrowser/#/R-SSC-9770141 Formation of the Spliceosomal C* complex IEA Sus scrofa A0A287AZF3 R-SSC-9770236 https://reactome.org/PathwayBrowser/#/R-SSC-9770236 Formation of the Spliceosomal P complex and exon ligation IEA Sus scrofa A0A287AZF3 R-SSC-9794542 https://reactome.org/PathwayBrowser/#/R-SSC-9794542 Formation of the Spliceosomal C complex containing intron lariat IEA Sus scrofa A0A287AZF5 R-SSC-114252 https://reactome.org/PathwayBrowser/#/R-SSC-114252 Cleavage of Procaspase-3 by the apoptosome IEA Sus scrofa A0A287AZF5 R-SSC-114254 https://reactome.org/PathwayBrowser/#/R-SSC-114254 CYCS binds to APAF1 IEA Sus scrofa A0A287AZF5 R-SSC-114256 https://reactome.org/PathwayBrowser/#/R-SSC-114256 CYCS:APAF1 binds procaspase-9 IEA Sus scrofa A0A287AZF5 R-SSC-114259 https://reactome.org/PathwayBrowser/#/R-SSC-114259 Cleavage of Procaspase‑9 to caspase‑9 IEA Sus scrofa A0A287AZF5 R-SSC-114261 https://reactome.org/PathwayBrowser/#/R-SSC-114261 Cleavage of Procaspase-7 by the apoptosome IEA Sus scrofa A0A287AZF5 R-SSC-114284 https://reactome.org/PathwayBrowser/#/R-SSC-114284 Release of Cytochrome c from mitochondria IEA Sus scrofa A0A287AZF5 R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa A0A287AZF5 R-SSC-164651 https://reactome.org/PathwayBrowser/#/R-SSC-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Sus scrofa A0A287AZF5 R-SSC-3341294 https://reactome.org/PathwayBrowser/#/R-SSC-3341294 Superoxide reduces cytochrome c IEA Sus scrofa A0A287AZF5 R-SSC-5688294 https://reactome.org/PathwayBrowser/#/R-SSC-5688294 SIRT5 deacetylates Cytochrome C IEA Sus scrofa A0A287AZF5 R-SSC-6804596 https://reactome.org/PathwayBrowser/#/R-SSC-6804596 APAF1:CYCS binds APIP IEA Sus scrofa A0A287AZF5 R-SSC-9627056 https://reactome.org/PathwayBrowser/#/R-SSC-9627056 Procaspase 9 forms dimer IEA Sus scrofa A0A287AZF5 R-SSC-9627078 https://reactome.org/PathwayBrowser/#/R-SSC-9627078 XIAP binds CASP9 IEA Sus scrofa A0A287AZF5 R-SSC-9627089 https://reactome.org/PathwayBrowser/#/R-SSC-9627089 CASP9 is phosphorylated at T412 IEA Sus scrofa A0A287AZF5 R-SSC-9866217 https://reactome.org/PathwayBrowser/#/R-SSC-9866217 HCCS inserts heme into cytochrome c IEA Sus scrofa A0A287AZF9 R-SSC-164651 https://reactome.org/PathwayBrowser/#/R-SSC-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Sus scrofa A0A287AZF9 R-SSC-9906042 https://reactome.org/PathwayBrowser/#/R-SSC-9906042 TTC19 clears UQCRFS1 fragments from Complex III IEA Sus scrofa A0A287AZG0 R-SSC-8981637 https://reactome.org/PathwayBrowser/#/R-SSC-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Sus scrofa A0A287AZG0 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa A0A287AZG0 R-SSC-9013022 https://reactome.org/PathwayBrowser/#/R-SSC-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Sus scrofa A0A287AZG0 R-SSC-9013024 https://reactome.org/PathwayBrowser/#/R-SSC-9013024 RHOB binds effectors at the plasma membrane IEA Sus scrofa A0A287AZG0 R-SSC-9013110 https://reactome.org/PathwayBrowser/#/R-SSC-9013110 RHOC binds effectors at the plasma membrane IEA Sus scrofa A0A287AZG0 R-SSC-9013111 https://reactome.org/PathwayBrowser/#/R-SSC-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Sus scrofa A0A287AZG0 R-SSC-9013144 https://reactome.org/PathwayBrowser/#/R-SSC-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Sus scrofa A0A287AZG0 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A287AZG0 R-SSC-9013161 https://reactome.org/PathwayBrowser/#/R-SSC-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Sus scrofa A0A287AZG0 R-SSC-9013437 https://reactome.org/PathwayBrowser/#/R-SSC-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Sus scrofa A0A287AZG0 R-SSC-9014295 https://reactome.org/PathwayBrowser/#/R-SSC-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Sus scrofa A0A287AZG0 R-SSC-9014434 https://reactome.org/PathwayBrowser/#/R-SSC-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Sus scrofa A0A287AZG0 R-SSC-9017488 https://reactome.org/PathwayBrowser/#/R-SSC-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Sus scrofa A0A287AZG0 R-SSC-9018745 https://reactome.org/PathwayBrowser/#/R-SSC-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Sus scrofa A0A287AZG0 R-SSC-9018746 https://reactome.org/PathwayBrowser/#/R-SSC-9018746 RHOQ binds effectors at the plasma membrane IEA Sus scrofa A0A287AZG0 R-SSC-9018806 https://reactome.org/PathwayBrowser/#/R-SSC-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Sus scrofa A0A287AZG0 R-SSC-9693125 https://reactome.org/PathwayBrowser/#/R-SSC-9693125 RHOF binds effectors at the plasma membrane IEA Sus scrofa A0A287AZG0 R-SSC-9693198 https://reactome.org/PathwayBrowser/#/R-SSC-9693198 RHOD binds effectors at the plasma membrane IEA Sus scrofa A0A287AZG0 R-SSC-9693282 https://reactome.org/PathwayBrowser/#/R-SSC-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Sus scrofa A0A287AZG0 R-SSC-9696266 https://reactome.org/PathwayBrowser/#/R-SSC-9696266 RND2 binds effectors IEA Sus scrofa A0A287AZH5 R-SSC-9844955 https://reactome.org/PathwayBrowser/#/R-SSC-9844955 CLN3 transports GalCer to plasma membrane IEA Sus scrofa A0A287AZI0 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A287AZI0 R-SSC-5672083 https://reactome.org/PathwayBrowser/#/R-SSC-5672083 KTN1 binds Kinesin-1 IEA Sus scrofa A0A287AZI0 R-SSC-6811423 https://reactome.org/PathwayBrowser/#/R-SSC-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs IEA Sus scrofa A0A287AZI0 R-SSC-6811426 https://reactome.org/PathwayBrowser/#/R-SSC-6811426 Retrograde COPI vesicles bind kinesin and microtubules IEA Sus scrofa A0A287AZI0 R-SSC-983194 https://reactome.org/PathwayBrowser/#/R-SSC-983194 Kinesin-1 is a heterotetramer IEA Sus scrofa A0A287AZI0 R-SSC-983259 https://reactome.org/PathwayBrowser/#/R-SSC-983259 Kinesins move along microtubules consuming ATP IEA Sus scrofa A0A287AZI0 R-SSC-983266 https://reactome.org/PathwayBrowser/#/R-SSC-983266 Kinesins bind microtubules IEA Sus scrofa A0A287AZJ1 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A287AZJ1 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A287AZJ1 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A287AZJ1 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A287AZJ1 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287AZJ1 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287AZJ1 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A287AZJ1 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287AZJ1 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287AZJ1 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287AZJ1 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287AZJ1 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A287AZJ1 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa A0A287AZJ1 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A287AZJ1 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A287AZJ1 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A287AZJ1 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa A0A287AZJ1 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A287AZJ1 R-SSC-9646348 https://reactome.org/PathwayBrowser/#/R-SSC-9646348 PolyUb-Misfolded Proteins:HDAC6 bind dynein motor IEA Sus scrofa A0A287AZJ1 R-SSC-9646679 https://reactome.org/PathwayBrowser/#/R-SSC-9646679 PolyUb-Misfolded proteins bind vimentin to form aggresome IEA Sus scrofa A0A287AZJ1 R-SSC-9646685 https://reactome.org/PathwayBrowser/#/R-SSC-9646685 Aggresome dissociates from dynein and microtubule IEA Sus scrofa A0A287AZJ1 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287AZK8 R-SSC-8953115 https://reactome.org/PathwayBrowser/#/R-SSC-8953115 E2F6:TFDP1 binds to MGA:MAX IEA Sus scrofa A0A287AZK8 R-SSC-8953418 https://reactome.org/PathwayBrowser/#/R-SSC-8953418 EHMT1:EHMT2 complex binds E2F6.com-1 core IEA Sus scrofa A0A287AZK8 R-SSC-9007283 https://reactome.org/PathwayBrowser/#/R-SSC-9007283 CBX3 and PRC1.6 associate with E2F6.com-1 IEA Sus scrofa A0A287AZM9 R-SSC-1236398 https://reactome.org/PathwayBrowser/#/R-SSC-1236398 ERBB4 binds NRGs or EGF-like ligands IEA Sus scrofa A0A287AZM9 R-SSC-1250195 https://reactome.org/PathwayBrowser/#/R-SSC-1250195 SHC1 phosphorylation by ERBB2 heterodimers IEA Sus scrofa A0A287AZM9 R-SSC-1250220 https://reactome.org/PathwayBrowser/#/R-SSC-1250220 Homodimerization of ERBB4 IEA Sus scrofa A0A287AZM9 R-SSC-1250315 https://reactome.org/PathwayBrowser/#/R-SSC-1250315 Trans-autophosphorylation of ERBB4 homodimers IEA Sus scrofa A0A287AZM9 R-SSC-1250346 https://reactome.org/PathwayBrowser/#/R-SSC-1250346 Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers IEA Sus scrofa A0A287AZM9 R-SSC-1250348 https://reactome.org/PathwayBrowser/#/R-SSC-1250348 Phosphorylation of SHC1 by ERBB4 homodimers IEA Sus scrofa A0A287AZM9 R-SSC-1250353 https://reactome.org/PathwayBrowser/#/R-SSC-1250353 Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers IEA Sus scrofa A0A287AZM9 R-SSC-1250357 https://reactome.org/PathwayBrowser/#/R-SSC-1250357 SHC1 binds P-ERBB4 isoform dimers IEA Sus scrofa A0A287AZM9 R-SSC-1250370 https://reactome.org/PathwayBrowser/#/R-SSC-1250370 Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers IEA Sus scrofa A0A287AZM9 R-SSC-1250380 https://reactome.org/PathwayBrowser/#/R-SSC-1250380 Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers IEA Sus scrofa A0A287AZM9 R-SSC-1250383 https://reactome.org/PathwayBrowser/#/R-SSC-1250383 RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 IEA Sus scrofa A0A287AZM9 R-SSC-1306969 https://reactome.org/PathwayBrowser/#/R-SSC-1306969 GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers IEA Sus scrofa A0A287AZM9 R-SSC-1306972 https://reactome.org/PathwayBrowser/#/R-SSC-1306972 RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers IEA Sus scrofa A0A287AZM9 R-SSC-1306979 https://reactome.org/PathwayBrowser/#/R-SSC-1306979 PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 IEA Sus scrofa A0A287AZM9 R-SSC-177922 https://reactome.org/PathwayBrowser/#/R-SSC-177922 EGFR dimerization IEA Sus scrofa A0A287AZM9 R-SSC-177923 https://reactome.org/PathwayBrowser/#/R-SSC-177923 Sustained activation of SRC kinase by SHP2 IEA Sus scrofa A0A287AZM9 R-SSC-177924 https://reactome.org/PathwayBrowser/#/R-SSC-177924 Dephosphorylation of Gab1 by SHP2 IEA Sus scrofa A0A287AZM9 R-SSC-177925 https://reactome.org/PathwayBrowser/#/R-SSC-177925 SHC1 binds to the phosphorylated EGF receptor:ligand complex IEA Sus scrofa A0A287AZM9 R-SSC-177926 https://reactome.org/PathwayBrowser/#/R-SSC-177926 Dephosphorylation of PAG by SHP2 IEA Sus scrofa A0A287AZM9 R-SSC-177927 https://reactome.org/PathwayBrowser/#/R-SSC-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 IEA Sus scrofa A0A287AZM9 R-SSC-177930 https://reactome.org/PathwayBrowser/#/R-SSC-177930 GAB1 phosphorylation by EGFR kinase IEA Sus scrofa A0A287AZM9 R-SSC-177933 https://reactome.org/PathwayBrowser/#/R-SSC-177933 SHC1 phosphorylation by phosphorylated EGFR IEA Sus scrofa A0A287AZM9 R-SSC-177934 https://reactome.org/PathwayBrowser/#/R-SSC-177934 EGFR autophosphorylation IEA Sus scrofa A0A287AZM9 R-SSC-177935 https://reactome.org/PathwayBrowser/#/R-SSC-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Sus scrofa A0A287AZM9 R-SSC-177936 https://reactome.org/PathwayBrowser/#/R-SSC-177936 GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR IEA Sus scrofa A0A287AZM9 R-SSC-177937 https://reactome.org/PathwayBrowser/#/R-SSC-177937 Phosphorylation of EGFR by SRC kinase IEA Sus scrofa A0A287AZM9 R-SSC-177938 https://reactome.org/PathwayBrowser/#/R-SSC-177938 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) IEA Sus scrofa A0A287AZM9 R-SSC-177939 https://reactome.org/PathwayBrowser/#/R-SSC-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) IEA Sus scrofa A0A287AZM9 R-SSC-177941 https://reactome.org/PathwayBrowser/#/R-SSC-177941 GRB2:GAB1 binds to phosphorylated EGFR IEA Sus scrofa A0A287AZM9 R-SSC-177942 https://reactome.org/PathwayBrowser/#/R-SSC-177942 EGFR binds EGF ligand IEA Sus scrofa A0A287AZM9 R-SSC-177943 https://reactome.org/PathwayBrowser/#/R-SSC-177943 GRB2:SOS1 complex binds to EGF:EGFR complex IEA Sus scrofa A0A287AZM9 R-SSC-177944 https://reactome.org/PathwayBrowser/#/R-SSC-177944 Activation of SHP2 through the binding to phospho-Gab1 IEA Sus scrofa A0A287AZM9 R-SSC-177945 https://reactome.org/PathwayBrowser/#/R-SSC-177945 SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) IEA Sus scrofa A0A287AZM9 R-SSC-182969 https://reactome.org/PathwayBrowser/#/R-SSC-182969 Phosphorylation of CBL (EGFR:CBL) IEA Sus scrofa A0A287AZM9 R-SSC-182986 https://reactome.org/PathwayBrowser/#/R-SSC-182986 CBL-mediated ubiquitination of CIN85 IEA Sus scrofa A0A287AZM9 R-SSC-182990 https://reactome.org/PathwayBrowser/#/R-SSC-182990 Sprouty sequesters CBL away from active EGFR IEA Sus scrofa A0A287AZM9 R-SSC-182993 https://reactome.org/PathwayBrowser/#/R-SSC-182993 Ubiquitination of stimulated EGFR (CBL) IEA Sus scrofa A0A287AZM9 R-SSC-182994 https://reactome.org/PathwayBrowser/#/R-SSC-182994 Assembly of EGFR complex in clathrin-coated vesicles IEA Sus scrofa A0A287AZM9 R-SSC-183002 https://reactome.org/PathwayBrowser/#/R-SSC-183002 Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 IEA Sus scrofa A0A287AZM9 R-SSC-183036 https://reactome.org/PathwayBrowser/#/R-SSC-183036 Ubiquitination of stimulated EGFR (CBL:GRB2) IEA Sus scrofa A0A287AZM9 R-SSC-183051 https://reactome.org/PathwayBrowser/#/R-SSC-183051 CBL ubiquitinates Sprouty IEA Sus scrofa A0A287AZM9 R-SSC-183055 https://reactome.org/PathwayBrowser/#/R-SSC-183055 Binding of CBL to EGFR IEA Sus scrofa A0A287AZM9 R-SSC-183058 https://reactome.org/PathwayBrowser/#/R-SSC-183058 Phosphorylation of CBL (EGFR:GRB2:CBL) IEA Sus scrofa A0A287AZM9 R-SSC-183067 https://reactome.org/PathwayBrowser/#/R-SSC-183067 Localization of CBL:GRB2 to the membrane IEA Sus scrofa A0A287AZM9 R-SSC-183072 https://reactome.org/PathwayBrowser/#/R-SSC-183072 EGFR non-clathrin mediated endocytosis IEA Sus scrofa A0A287AZM9 R-SSC-183084 https://reactome.org/PathwayBrowser/#/R-SSC-183084 CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix IEA Sus scrofa A0A287AZM9 R-SSC-183089 https://reactome.org/PathwayBrowser/#/R-SSC-183089 CBL binds and ubiquitinates phosphorylated Sprouty IEA Sus scrofa A0A287AZM9 R-SSC-1963563 https://reactome.org/PathwayBrowser/#/R-SSC-1963563 MATK (CSK homologous kinase) binds phosphorylated ERBB2 IEA Sus scrofa A0A287AZM9 R-SSC-1963581 https://reactome.org/PathwayBrowser/#/R-SSC-1963581 Trans-autophosphorylation of p-Y877-ERBB2 heterodimers IEA Sus scrofa A0A287AZM9 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa A0A287AZM9 R-SSC-1963586 https://reactome.org/PathwayBrowser/#/R-SSC-1963586 SRC family kinases phosphorylate ERBB2 IEA Sus scrofa A0A287AZM9 R-SSC-1977958 https://reactome.org/PathwayBrowser/#/R-SSC-1977958 ERBB4 forms heterodimers with ERBB3 IEA Sus scrofa A0A287AZM9 R-SSC-1977959 https://reactome.org/PathwayBrowser/#/R-SSC-1977959 ERBB4 forms heterodimers with EGFR IEA Sus scrofa A0A287AZM9 R-SSC-212706 https://reactome.org/PathwayBrowser/#/R-SSC-212706 Phospholipase C-gamma1 binds to the activated EGF receptor IEA Sus scrofa A0A287AZM9 R-SSC-212710 https://reactome.org/PathwayBrowser/#/R-SSC-212710 EGFR activates PLC-gamma1 by phosphorylation IEA Sus scrofa A0A287AZM9 R-SSC-212713 https://reactome.org/PathwayBrowser/#/R-SSC-212713 Active PLC-gamma1 dissociates from EGFR IEA Sus scrofa A0A287AZM9 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287AZM9 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287AZM9 R-SSC-6785636 https://reactome.org/PathwayBrowser/#/R-SSC-6785636 Phosphorylated ERBB2 heterodimers bind MEMO1 IEA Sus scrofa A0A287AZM9 R-SSC-6785648 https://reactome.org/PathwayBrowser/#/R-SSC-6785648 MEMO1 binds RHOA:GTP:DIAPH1 IEA Sus scrofa A0A287AZM9 R-SSC-8847995 https://reactome.org/PathwayBrowser/#/R-SSC-8847995 Activated ERBB2 binds PTK6 (BRK) IEA Sus scrofa A0A287AZM9 R-SSC-8848005 https://reactome.org/PathwayBrowser/#/R-SSC-8848005 ERBB2 promotes PTK6 autophosphorylation IEA Sus scrofa A0A287AZM9 R-SSC-8863804 https://reactome.org/PathwayBrowser/#/R-SSC-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Sus scrofa A0A287AZM9 R-SSC-8866279 https://reactome.org/PathwayBrowser/#/R-SSC-8866279 Epsin family proteins bind ubiquitinated cargo IEA Sus scrofa A0A287AZM9 R-SSC-8867041 https://reactome.org/PathwayBrowser/#/R-SSC-8867041 EGFR phosphorylates EPS15 IEA Sus scrofa A0A287AZM9 R-SSC-8867044 https://reactome.org/PathwayBrowser/#/R-SSC-8867044 EGFR binds EPS15, EPN1, EPS15L1 IEA Sus scrofa A0A287AZM9 R-SSC-8867047 https://reactome.org/PathwayBrowser/#/R-SSC-8867047 PTPN3 dephosphorylates EPS15 IEA Sus scrofa A0A287AZM9 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A287AZM9 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A287AZM9 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A287AZM9 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A287AZM9 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A287AZM9 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287AZM9 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287AZM9 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287AZM9 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287AZM9 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287AZM9 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287AZM9 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287AZM9 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287AZM9 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287AZM9 R-SSC-8951490 https://reactome.org/PathwayBrowser/#/R-SSC-8951490 CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 IEA Sus scrofa A0A287AZP0 R-SSC-2161282 https://reactome.org/PathwayBrowser/#/R-SSC-2161282 Elastic fibres bind associated proteins IEA Sus scrofa A0A287AZP4 R-SSC-5687758 https://reactome.org/PathwayBrowser/#/R-SSC-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Sus scrofa A0A287AZP5 R-SSC-390438 https://reactome.org/PathwayBrowser/#/R-SSC-390438 FAR2 reduces PalmCoA to HXOL IEA Sus scrofa A0A287AZQ6 R-SSC-110137 https://reactome.org/PathwayBrowser/#/R-SSC-110137 (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP IEA Sus scrofa A0A287AZQ6 R-SSC-110138 https://reactome.org/PathwayBrowser/#/R-SSC-110138 AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs IEA Sus scrofa A0A287AZS0 R-SSC-3000383 https://reactome.org/PathwayBrowser/#/R-SSC-3000383 UBE2I, HDAC7 SUMOylate PML with SUMO1 IEA Sus scrofa A0A287AZS0 R-SSC-3000411 https://reactome.org/PathwayBrowser/#/R-SSC-3000411 RANBP2 SUMOylates PML with SUMO2 IEA Sus scrofa A0A287AZS0 R-SSC-3000433 https://reactome.org/PathwayBrowser/#/R-SSC-3000433 SUMOylation of PML with SUMO3 IEA Sus scrofa A0A287AZS0 R-SSC-3000434 https://reactome.org/PathwayBrowser/#/R-SSC-3000434 PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1 IEA Sus scrofa A0A287AZS0 R-SSC-5228508 https://reactome.org/PathwayBrowser/#/R-SSC-5228508 RANBP2 SUMOylates PML with SUMO1 IEA Sus scrofa A0A287AZS0 R-SSC-6805620 https://reactome.org/PathwayBrowser/#/R-SSC-6805620 KAT6A and PML bind TP53 IEA Sus scrofa A0A287AZS0 R-SSC-6805638 https://reactome.org/PathwayBrowser/#/R-SSC-6805638 KAT6A acetylates TP53 IEA Sus scrofa A0A287AZS0 R-SSC-6805650 https://reactome.org/PathwayBrowser/#/R-SSC-6805650 MTA2-NuRD complex deacetylates TP53 IEA Sus scrofa A0A287AZS0 R-SSC-6807118 https://reactome.org/PathwayBrowser/#/R-SSC-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Sus scrofa A0A287AZS0 R-SSC-8938887 https://reactome.org/PathwayBrowser/#/R-SSC-8938887 PML binds RUNX1 IEA Sus scrofa A0A287AZS7 R-SSC-9619376 https://reactome.org/PathwayBrowser/#/R-SSC-9619376 CAMK1 binds calmodulin IEA Sus scrofa A0A287AZU8 R-SSC-6799545 https://reactome.org/PathwayBrowser/#/R-SSC-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Sus scrofa A0A287AZV4 R-SSC-5692237 https://reactome.org/PathwayBrowser/#/R-SSC-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Sus scrofa A0A287AZY0 R-SSC-8949178 https://reactome.org/PathwayBrowser/#/R-SSC-8949178 MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix IEA Sus scrofa A0A287AZY0 R-SSC-8953461 https://reactome.org/PathwayBrowser/#/R-SSC-8953461 SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex IEA Sus scrofa A0A287AZY6 R-SSC-8874470 https://reactome.org/PathwayBrowser/#/R-SSC-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane IEA Sus scrofa A0A287B001 R-SSC-8855232 https://reactome.org/PathwayBrowser/#/R-SSC-8855232 RELN:VLDLR binds DAB1 IEA Sus scrofa A0A287B001 R-SSC-8855237 https://reactome.org/PathwayBrowser/#/R-SSC-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 IEA Sus scrofa A0A287B001 R-SSC-8855259 https://reactome.org/PathwayBrowser/#/R-SSC-8855259 RELN:VLDLR:DAB1 binds SH3KBP1 IEA Sus scrofa A0A287B011 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287B011 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287B011 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287B011 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287B029 R-SSC-196126 https://reactome.org/PathwayBrowser/#/R-SSC-196126 CHOL translocates from cytosol to mitochondrial intermembrane space IEA Sus scrofa A0A287B030 R-SSC-70577 https://reactome.org/PathwayBrowser/#/R-SSC-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA IEA Sus scrofa A0A287B031 R-SSC-2162192 https://reactome.org/PathwayBrowser/#/R-SSC-2162192 COQ2 ligates all-E-10PrP2 to PHB IEA Sus scrofa A0A287B031 R-SSC-8986181 https://reactome.org/PathwayBrowser/#/R-SSC-8986181 PITRM1 proteolyzes mitochondrial targeting peptides (presequences) IEA Sus scrofa A0A287B032 R-SSC-8877612 https://reactome.org/PathwayBrowser/#/R-SSC-8877612 DENND1s exchange GTP for GDP on RAB35 IEA Sus scrofa A0A287B032 R-SSC-8933452 https://reactome.org/PathwayBrowser/#/R-SSC-8933452 YWHAE dimer binds phosphorylated DENND1 proteins IEA Sus scrofa A0A287B049 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A287B082 R-SSC-210420 https://reactome.org/PathwayBrowser/#/R-SSC-210420 Ca2+ influx through voltage gated Ca2+ channels IEA Sus scrofa A0A287B082 R-SSC-5577213 https://reactome.org/PathwayBrowser/#/R-SSC-5577213 LTCC multimer transports Ca2+ from extracellular region to cytosol IEA Sus scrofa A0A287B082 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa A0A287B0A0 R-SSC-5164399 https://reactome.org/PathwayBrowser/#/R-SSC-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Sus scrofa A0A287B0A6 R-SSC-1299318 https://reactome.org/PathwayBrowser/#/R-SSC-1299318 Activation of TASK IEA Sus scrofa A0A287B0A6 R-SSC-5578910 https://reactome.org/PathwayBrowser/#/R-SSC-5578910 KCNK dimers transport K+ from cytosol to extracellular region IEA Sus scrofa A0A287B0B3 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287B0B4 R-SSC-429955 https://reactome.org/PathwayBrowser/#/R-SSC-429955 CCR4-NOT complex deadenylates mRNA IEA Sus scrofa A0A287B0B4 R-SSC-6798044 https://reactome.org/PathwayBrowser/#/R-SSC-6798044 BTG2 binds CCR4-NOT complex IEA Sus scrofa A0A287B0C3 R-SSC-164832 https://reactome.org/PathwayBrowser/#/R-SSC-164832 ATPase synthesizes ATP IEA Sus scrofa A0A287B0C3 R-SSC-164834 https://reactome.org/PathwayBrowser/#/R-SSC-164834 Enzyme-bound ATP is released IEA Sus scrofa A0A287B0C3 R-SSC-164840 https://reactome.org/PathwayBrowser/#/R-SSC-164840 ADP and Pi bind to ATPase IEA Sus scrofa A0A287B0C3 R-SSC-8949580 https://reactome.org/PathwayBrowser/#/R-SSC-8949580 F1Fo ATP synthase dimerizes IEA Sus scrofa A0A287B0C3 R-SSC-9837978 https://reactome.org/PathwayBrowser/#/R-SSC-9837978 LONP1 binds mitochondrial inner membrane proteins IEA Sus scrofa A0A287B0C3 R-SSC-9838004 https://reactome.org/PathwayBrowser/#/R-SSC-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Sus scrofa A0A287B0C4 R-SSC-351901 https://reactome.org/PathwayBrowser/#/R-SSC-351901 Caspase-mediated cleavage of MST3 IEA Sus scrofa A0A287B0C4 R-SSC-351947 https://reactome.org/PathwayBrowser/#/R-SSC-351947 Nuclear translocation of catalytic domain of Mst3 IEA Sus scrofa A0A287B0C5 R-SSC-2022860 https://reactome.org/PathwayBrowser/#/R-SSC-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Sus scrofa A0A287B0C5 R-SSC-2022887 https://reactome.org/PathwayBrowser/#/R-SSC-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Sus scrofa A0A287B0D0 R-SSC-481007 https://reactome.org/PathwayBrowser/#/R-SSC-481007 Exocytosis of platelet alpha granule contents IEA Sus scrofa A0A287B0D3 R-SSC-3928627 https://reactome.org/PathwayBrowser/#/R-SSC-3928627 EPHB phosphorylates TIAM1 IEA Sus scrofa A0A287B0D3 R-SSC-3928645 https://reactome.org/PathwayBrowser/#/R-SSC-3928645 EPHB:NMDAR binds TIAM1 IEA Sus scrofa A0A287B0D3 R-SSC-4093336 https://reactome.org/PathwayBrowser/#/R-SSC-4093336 p-TIAM1 exchanges GTP for GDP on RAC1, activating it IEA Sus scrofa A0A287B0D3 R-SSC-432164 https://reactome.org/PathwayBrowser/#/R-SSC-432164 Ca2+ influx into the post-synaptic cell IEA Sus scrofa A0A287B0D3 R-SSC-438037 https://reactome.org/PathwayBrowser/#/R-SSC-438037 Membrane depolarization upon activation of Ca impermeable AMPA receptors IEA Sus scrofa A0A287B0D3 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287B0D3 R-SSC-8849878 https://reactome.org/PathwayBrowser/#/R-SSC-8849878 PSD-95 binds NMDA receptor IEA Sus scrofa A0A287B0D3 R-SSC-8849906 https://reactome.org/PathwayBrowser/#/R-SSC-8849906 SALM1 binds NMDA receptor IEA Sus scrofa A0A287B0D3 R-SSC-9609742 https://reactome.org/PathwayBrowser/#/R-SSC-9609742 Formation of di-heterotetramers of GluN1 (GRIN1) and GluN2A (GRIN2A) IEA Sus scrofa A0A287B0D3 R-SSC-9609743 https://reactome.org/PathwayBrowser/#/R-SSC-9609743 Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3A (GRIN3A) IEA Sus scrofa A0A287B0D3 R-SSC-9610750 https://reactome.org/PathwayBrowser/#/R-SSC-9610750 GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane IEA Sus scrofa A0A287B0E4 R-SSC-8952289 https://reactome.org/PathwayBrowser/#/R-SSC-8952289 FAM20C phosphorylates FAM20C substrates IEA Sus scrofa A0A287B0E4 R-SSC-975903 https://reactome.org/PathwayBrowser/#/R-SSC-975903 Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV IEA Sus scrofa A0A287B0E9 R-SSC-382053 https://reactome.org/PathwayBrowser/#/R-SSC-382053 Translocation of PDGF from ER to Golgi IEA Sus scrofa A0A287B0E9 R-SSC-382057 https://reactome.org/PathwayBrowser/#/R-SSC-382057 Release of novel PDGFs as latent factors IEA Sus scrofa A0A287B0E9 R-SSC-382061 https://reactome.org/PathwayBrowser/#/R-SSC-382061 Extracellular processing of novel PDGFs IEA Sus scrofa A0A287B0I3 R-SSC-9012835 https://reactome.org/PathwayBrowser/#/R-SSC-9012835 GDIs block activation of RHOA IEA Sus scrofa A0A287B0I3 R-SSC-9013147 https://reactome.org/PathwayBrowser/#/R-SSC-9013147 RAC1 GDIs block activation of RAC1 IEA Sus scrofa A0A287B0I3 R-SSC-9013158 https://reactome.org/PathwayBrowser/#/R-SSC-9013158 CDC42 GDIs block activation of CDC42 IEA Sus scrofa A0A287B0I3 R-SSC-9014456 https://reactome.org/PathwayBrowser/#/R-SSC-9014456 GDIs block activation of RHOG IEA Sus scrofa A0A287B0I3 R-SSC-9018754 https://reactome.org/PathwayBrowser/#/R-SSC-9018754 GDIs bind RHOH IEA Sus scrofa A0A287B0I3 R-SSC-9018807 https://reactome.org/PathwayBrowser/#/R-SSC-9018807 RAC3 GDIs block activation of RAC3 IEA Sus scrofa A0A287B0I5 R-SSC-1475017 https://reactome.org/PathwayBrowser/#/R-SSC-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Sus scrofa A0A287B0I5 R-SSC-1475025 https://reactome.org/PathwayBrowser/#/R-SSC-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Sus scrofa A0A287B0I6 R-SSC-159790 https://reactome.org/PathwayBrowser/#/R-SSC-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa A0A287B0I6 R-SSC-9026967 https://reactome.org/PathwayBrowser/#/R-SSC-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Sus scrofa A0A287B0J2 R-SSC-5692775 https://reactome.org/PathwayBrowser/#/R-SSC-5692775 SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs IEA Sus scrofa A0A287B0J2 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A287B0J7 R-SSC-350567 https://reactome.org/PathwayBrowser/#/R-SSC-350567 Antizyme OAZ binds to Ornithine decarboxylase IEA Sus scrofa A0A287B0J7 R-SSC-350600 https://reactome.org/PathwayBrowser/#/R-SSC-350600 Antizyme inhibitor binds to OAZ and stablizes ODC complex IEA Sus scrofa A0A287B0J7 R-SSC-353125 https://reactome.org/PathwayBrowser/#/R-SSC-353125 26S proteosome degrades ODC holoenzyme complex IEA Sus scrofa A0A287B0J8 R-SSC-5633051 https://reactome.org/PathwayBrowser/#/R-SSC-5633051 EFCAB7:IQCE binds EVC2:EVC IEA Sus scrofa A0A287B0J8 R-SSC-5635859 https://reactome.org/PathwayBrowser/#/R-SSC-5635859 GLI:SUFU dissociates IEA Sus scrofa A0A287B0J9 R-SSC-9933236 https://reactome.org/PathwayBrowser/#/R-SSC-9933236 SS18-containing ATPase complex binds SMARCC dimer:SMARCDs:BICRAs:BRD9 IEA Sus scrofa A0A287B0J9 R-SSC-9933238 https://reactome.org/PathwayBrowser/#/R-SSC-9933238 SS18-containing ATPase complex binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1:DPF1,2,3 IEA Sus scrofa A0A287B0K1 R-SSC-927813 https://reactome.org/PathwayBrowser/#/R-SSC-927813 p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A IEA Sus scrofa A0A287B0K1 R-SSC-927832 https://reactome.org/PathwayBrowser/#/R-SSC-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex IEA Sus scrofa A0A287B0K1 R-SSC-927889 https://reactome.org/PathwayBrowser/#/R-SSC-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) IEA Sus scrofa A0A287B0L2 R-SSC-212380 https://reactome.org/PathwayBrowser/#/R-SSC-212380 Formation of TRAP coactivator complex IEA Sus scrofa A0A287B0L2 R-SSC-9843120 https://reactome.org/PathwayBrowser/#/R-SSC-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Sus scrofa A0A287B0L6 R-SSC-3662335 https://reactome.org/PathwayBrowser/#/R-SSC-3662335 EP300 acetylates histone H2A, H2B, H3, H4 IEA Sus scrofa A0A287B0L6 R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa A0A287B0L6 R-SSC-3777129 https://reactome.org/PathwayBrowser/#/R-SSC-3777129 HDAC3 containing complexes deacetylate histone IEA Sus scrofa A0A287B0L6 R-SSC-3782637 https://reactome.org/PathwayBrowser/#/R-SSC-3782637 HDAC8 deacetylates histones IEA Sus scrofa A0A287B0L6 R-SSC-3782655 https://reactome.org/PathwayBrowser/#/R-SSC-3782655 HDAC10 deacetylates histone IEA Sus scrofa A0A287B0L6 R-SSC-5205820 https://reactome.org/PathwayBrowser/#/R-SSC-5205820 PRMT6 methylates arginine-4 of histone H2A (H2AR3) IEA Sus scrofa A0A287B0L6 R-SSC-5205867 https://reactome.org/PathwayBrowser/#/R-SSC-5205867 PRMT1 methylates arginine-12 of histone H2A (H2AR11) IEA Sus scrofa A0A287B0L6 R-SSC-5216234 https://reactome.org/PathwayBrowser/#/R-SSC-5216234 PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) IEA Sus scrofa A0A287B0L6 R-SSC-5229203 https://reactome.org/PathwayBrowser/#/R-SSC-5229203 PRMT6 methylates histone H2A arginine-30 (H2AR29) IEA Sus scrofa A0A287B0L6 R-SSC-5690080 https://reactome.org/PathwayBrowser/#/R-SSC-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Sus scrofa A0A287B0L6 R-SSC-5690157 https://reactome.org/PathwayBrowser/#/R-SSC-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Sus scrofa A0A287B0L6 R-SSC-5690790 https://reactome.org/PathwayBrowser/#/R-SSC-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Sus scrofa A0A287B0L6 R-SSC-5691381 https://reactome.org/PathwayBrowser/#/R-SSC-5691381 MYSM1 deubiquitinates Histone H2A IEA Sus scrofa A0A287B0L6 R-SSC-5691411 https://reactome.org/PathwayBrowser/#/R-SSC-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Sus scrofa A0A287B0M2 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287B0M2 R-SSC-444731 https://reactome.org/PathwayBrowser/#/R-SSC-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Sus scrofa A0A287B0M2 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287B0M2 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287B0N2 R-SSC-166214 https://reactome.org/PathwayBrowser/#/R-SSC-166214 FA anion flip-flops to the opposite surface IEA Sus scrofa A0A287B0N2 R-SSC-166220 https://reactome.org/PathwayBrowser/#/R-SSC-166220 FA anion diffuses laterally to UCP IEA Sus scrofa A0A287B0N2 R-SSC-166387 https://reactome.org/PathwayBrowser/#/R-SSC-166387 The FA anion diffuses away laterally from UCP IEA Sus scrofa A0A287B0Q7 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa A0A287B0Q7 R-SSC-9656244 https://reactome.org/PathwayBrowser/#/R-SSC-9656244 DRD2 binds DA IEA Sus scrofa A0A287B0R8 R-SSC-1236943 https://reactome.org/PathwayBrowser/#/R-SSC-1236943 Loading of antigen peptide onto MHC class I molecule IEA Sus scrofa A0A287B0R8 R-SSC-1236954 https://reactome.org/PathwayBrowser/#/R-SSC-1236954 Trimming of peptides by IRAP in endocytic vesicles IEA Sus scrofa A0A287B0R8 R-SSC-1236964 https://reactome.org/PathwayBrowser/#/R-SSC-1236964 Translocation of peptide bound MHC class I complex to cell surface IEA Sus scrofa A0A287B0R8 R-SSC-1236965 https://reactome.org/PathwayBrowser/#/R-SSC-1236965 Export of peptide loaded MHC class I complex to PM IEA Sus scrofa A0A287B0R8 R-SSC-198955 https://reactome.org/PathwayBrowser/#/R-SSC-198955 TCR complex interacts with peptide antigen-presenting MHC Class I IEA Sus scrofa A0A287B0R8 R-SSC-198958 https://reactome.org/PathwayBrowser/#/R-SSC-198958 KIR2DL2/3 interacting with HLA-C group 1 (Cw4) IEA Sus scrofa A0A287B0R8 R-SSC-199558 https://reactome.org/PathwayBrowser/#/R-SSC-199558 KIR2DL1 interacting with HLA-C group 2 (Cw3) IEA Sus scrofa A0A287B0R8 R-SSC-199566 https://reactome.org/PathwayBrowser/#/R-SSC-199566 KIR3DL1 interacting with HLA Bw4 IEA Sus scrofa A0A287B0R8 R-SSC-199583 https://reactome.org/PathwayBrowser/#/R-SSC-199583 KIR2DS2 interacting with HLA-C group 1 (Cw3) IEA Sus scrofa A0A287B0R8 R-SSC-199587 https://reactome.org/PathwayBrowser/#/R-SSC-199587 KIR2DS1 interacting with HLA-C group 2 (Cw4) IEA Sus scrofa A0A287B0R8 R-SSC-210298 https://reactome.org/PathwayBrowser/#/R-SSC-210298 Interaction of DAP12 and KIR3DS1 IEA Sus scrofa A0A287B0R8 R-SSC-210309 https://reactome.org/PathwayBrowser/#/R-SSC-210309 Interaction of DAP12 and KIR2DS2 IEA Sus scrofa A0A287B0R8 R-SSC-2272753 https://reactome.org/PathwayBrowser/#/R-SSC-2272753 Interaction of DAP12 and KIR2DS4 IEA Sus scrofa A0A287B0R8 R-SSC-2272795 https://reactome.org/PathwayBrowser/#/R-SSC-2272795 Interaction of DAP12 and KIR2DS1 IEA Sus scrofa A0A287B0R8 R-SSC-6798739 https://reactome.org/PathwayBrowser/#/R-SSC-6798739 Exocytosis of azurophil granule membrane proteins IEA Sus scrofa A0A287B0R8 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A287B0R8 R-SSC-8863973 https://reactome.org/PathwayBrowser/#/R-SSC-8863973 Fusion of ERC and phagosome IEA Sus scrofa A0A287B0R8 R-SSC-8951499 https://reactome.org/PathwayBrowser/#/R-SSC-8951499 Loading of antigenic peptides on to class I MHC IEA Sus scrofa A0A287B0R8 R-SSC-983138 https://reactome.org/PathwayBrowser/#/R-SSC-983138 Transport of MHC heterotrimer to ER exit site IEA Sus scrofa A0A287B0R8 R-SSC-983142 https://reactome.org/PathwayBrowser/#/R-SSC-983142 Formation of peptide loading complex (PLC) IEA Sus scrofa A0A287B0R8 R-SSC-983145 https://reactome.org/PathwayBrowser/#/R-SSC-983145 Binding of newly synthesized MHC class I heavy chain (HC) with calnexin IEA Sus scrofa A0A287B0R8 R-SSC-983146 https://reactome.org/PathwayBrowser/#/R-SSC-983146 Interaction of beta-2-microglobulin (B2M) chain with class I HC IEA Sus scrofa A0A287B0R8 R-SSC-983161 https://reactome.org/PathwayBrowser/#/R-SSC-983161 Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex IEA Sus scrofa A0A287B0R8 R-SSC-983421 https://reactome.org/PathwayBrowser/#/R-SSC-983421 Journey of cargo through Golgi complex IEA Sus scrofa A0A287B0R8 R-SSC-983422 https://reactome.org/PathwayBrowser/#/R-SSC-983422 Disassembly of COPII coated vesicle IEA Sus scrofa A0A287B0R8 R-SSC-983424 https://reactome.org/PathwayBrowser/#/R-SSC-983424 Budding of COPII coated vesicle IEA Sus scrofa A0A287B0R8 R-SSC-983425 https://reactome.org/PathwayBrowser/#/R-SSC-983425 Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle IEA Sus scrofa A0A287B0R8 R-SSC-983427 https://reactome.org/PathwayBrowser/#/R-SSC-983427 Expression of peptide bound class I MHC on cell surface IEA Sus scrofa A0A287B0T0 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287B0T0 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287B0T0 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287B0T0 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287B0T7 R-SSC-74986 https://reactome.org/PathwayBrowser/#/R-SSC-74986 Elongation of pre-rRNA transcript IEA Sus scrofa A0A287B0T7 R-SSC-9007283 https://reactome.org/PathwayBrowser/#/R-SSC-9007283 CBX3 and PRC1.6 associate with E2F6.com-1 IEA Sus scrofa A0A287B0T7 R-SSC-9007447 https://reactome.org/PathwayBrowser/#/R-SSC-9007447 E2F6 forms the PRC1L4 complex IEA Sus scrofa A0A287B0U9 R-SSC-6814695 https://reactome.org/PathwayBrowser/#/R-SSC-6814695 PERP binds desmosomes IEA Sus scrofa A0A287B0V1 R-SSC-4084976 https://reactome.org/PathwayBrowser/#/R-SSC-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Sus scrofa A0A287B0V6 R-SSC-372693 https://reactome.org/PathwayBrowser/#/R-SSC-372693 Phosphorylation of BCAR1 by SRC-PTK2 complex IEA Sus scrofa A0A287B0V6 R-SSC-372697 https://reactome.org/PathwayBrowser/#/R-SSC-372697 Crk binding to p130cas IEA Sus scrofa A0A287B0V6 R-SSC-372705 https://reactome.org/PathwayBrowser/#/R-SSC-372705 Recruitment of BCAR1 to PTK2 complex IEA Sus scrofa A0A287B0V6 R-SSC-382052 https://reactome.org/PathwayBrowser/#/R-SSC-382052 p130Cas and C3G bind PDGFR bound Crk IEA Sus scrofa A0A287B0V6 R-SSC-5218811 https://reactome.org/PathwayBrowser/#/R-SSC-5218811 DOCK180:ELMO binds CRK IEA Sus scrofa A0A287B0V6 R-SSC-5218822 https://reactome.org/PathwayBrowser/#/R-SSC-5218822 CRK binds BCAR1 and or PXN IEA Sus scrofa A0A287B0V6 R-SSC-5218839 https://reactome.org/PathwayBrowser/#/R-SSC-5218839 DOCK180:ELMO exchanges GTP for GDP, activating RAC1 IEA Sus scrofa A0A287B0V6 R-SSC-8848713 https://reactome.org/PathwayBrowser/#/R-SSC-8848713 PTK6 binds BCAR1 IEA Sus scrofa A0A287B0V6 R-SSC-8848726 https://reactome.org/PathwayBrowser/#/R-SSC-8848726 PTK6 phosphorylates BCAR1 IEA Sus scrofa A0A287B113 R-SSC-75079 https://reactome.org/PathwayBrowser/#/R-SSC-75079 Formation of AT-AC C complex IEA Sus scrofa A0A287B113 R-SSC-75081 https://reactome.org/PathwayBrowser/#/R-SSC-75081 Formation of AT-AC B Complex IEA Sus scrofa A0A287B113 R-SSC-75082 https://reactome.org/PathwayBrowser/#/R-SSC-75082 ATAC spliceosome mediated Lariat formation,5' splice site cleavage IEA Sus scrofa A0A287B113 R-SSC-75083 https://reactome.org/PathwayBrowser/#/R-SSC-75083 ATAC spliceosome mediated 3' splice site cleavage, exon ligation IEA Sus scrofa A0A287B122 R-SSC-2046088 https://reactome.org/PathwayBrowser/#/R-SSC-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Sus scrofa A0A287B122 R-SSC-2046094 https://reactome.org/PathwayBrowser/#/R-SSC-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Sus scrofa A0A287B122 R-SSC-548800 https://reactome.org/PathwayBrowser/#/R-SSC-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Sus scrofa A0A287B129 R-SSC-5693681 https://reactome.org/PathwayBrowser/#/R-SSC-5693681 DUOX1,2 reduce O2 to H2O2 IEA Sus scrofa A0A287B139 R-SSC-374251 https://reactome.org/PathwayBrowser/#/R-SSC-374251 DARC is a non-specific receptor for many chemokines IEA Sus scrofa A0A287B140 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287B165 R-SSC-114552 https://reactome.org/PathwayBrowser/#/R-SSC-114552 Thrombin-activated PARs activate G12/13 IEA Sus scrofa A0A287B165 R-SSC-114558 https://reactome.org/PathwayBrowser/#/R-SSC-114558 Thrombin-activated PARs activate Gq IEA Sus scrofa A0A287B165 R-SSC-114697 https://reactome.org/PathwayBrowser/#/R-SSC-114697 Activated thrombin (factor IIa) cleaves PAR3,4, activating them IEA Sus scrofa A0A287B165 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa A0A287B165 R-SSC-389463 https://reactome.org/PathwayBrowser/#/R-SSC-389463 Proteinase-activated receptors can bind thrombin IEA Sus scrofa A0A287B165 R-SSC-396996 https://reactome.org/PathwayBrowser/#/R-SSC-396996 Thrombin-activated PARs binds G-protein Gq IEA Sus scrofa A0A287B165 R-SSC-397835 https://reactome.org/PathwayBrowser/#/R-SSC-397835 Thrombin-activated PARs:Gq (active) dissociate IEA Sus scrofa A0A287B165 R-SSC-397891 https://reactome.org/PathwayBrowser/#/R-SSC-397891 Thrombin-activated PARs:G12/13 (active) dissociate IEA Sus scrofa A0A287B165 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa A0A287B165 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa A0A287B174 R-SSC-201510 https://reactome.org/PathwayBrowser/#/R-SSC-201510 PI3K synthesizes PIP3 downstream of ALK IEA Sus scrofa A0A287B174 R-SSC-201515 https://reactome.org/PathwayBrowser/#/R-SSC-201515 Active ALK recruits PI3K IEA Sus scrofa A0A287B174 R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa A0A287B174 R-SSC-9700149 https://reactome.org/PathwayBrowser/#/R-SSC-9700149 Active ALK binds PLCG1 IEA Sus scrofa A0A287B174 R-SSC-9700154 https://reactome.org/PathwayBrowser/#/R-SSC-9700154 Active ALK binds SHC1 IEA Sus scrofa A0A287B174 R-SSC-9700156 https://reactome.org/PathwayBrowser/#/R-SSC-9700156 Active ALK dimer binds IRS1 IEA Sus scrofa A0A287B174 R-SSC-9700168 https://reactome.org/PathwayBrowser/#/R-SSC-9700168 Active ALK phosphorylates IRS1 IEA Sus scrofa A0A287B174 R-SSC-9700171 https://reactome.org/PathwayBrowser/#/R-SSC-9700171 Active ALK phosphorylates PLCG1 IEA Sus scrofa A0A287B174 R-SSC-9700175 https://reactome.org/PathwayBrowser/#/R-SSC-9700175 Active ALK phosphorylates SHC1 IEA Sus scrofa A0A287B174 R-SSC-9700662 https://reactome.org/PathwayBrowser/#/R-SSC-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Sus scrofa A0A287B174 R-SSC-9701485 https://reactome.org/PathwayBrowser/#/R-SSC-9701485 Active ALK binds JAK3 IEA Sus scrofa A0A287B174 R-SSC-9701488 https://reactome.org/PathwayBrowser/#/R-SSC-9701488 Active ALK phosphorylates JAK3 IEA Sus scrofa A0A287B174 R-SSC-9701507 https://reactome.org/PathwayBrowser/#/R-SSC-9701507 PTPN6 dephosphorylates JAK3 IEA Sus scrofa A0A287B174 R-SSC-9701524 https://reactome.org/PathwayBrowser/#/R-SSC-9701524 STAT3 is phosphorylated downstream of active ALK IEA Sus scrofa A0A287B174 R-SSC-9842656 https://reactome.org/PathwayBrowser/#/R-SSC-9842656 ALK binds ALKAL ligand IEA Sus scrofa A0A287B186 R-SSC-9013004 https://reactome.org/PathwayBrowser/#/R-SSC-9013004 RHOA binds effectors at the ER membrane IEA Sus scrofa A0A287B186 R-SSC-9014467 https://reactome.org/PathwayBrowser/#/R-SSC-9014467 RHOG binds effectors at the ER membrane IEA Sus scrofa A0A287B186 R-SSC-9693250 https://reactome.org/PathwayBrowser/#/R-SSC-9693250 RHOD binds effectors at the Golgi membrane IEA Sus scrofa A0A287B186 R-SSC-9714361 https://reactome.org/PathwayBrowser/#/R-SSC-9714361 RHOC activates endoplasmic reticulum effectors IEA Sus scrofa A0A287B186 R-SSC-9714481 https://reactome.org/PathwayBrowser/#/R-SSC-9714481 RAC2 binds effectors at the ER membrane IEA Sus scrofa A0A287B198 R-SSC-8863463 https://reactome.org/PathwayBrowser/#/R-SSC-8863463 STON2 binds SYT proteins IEA Sus scrofa A0A287B198 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa A0A287B198 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa A0A287B198 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa A0A287B198 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa A0A287B198 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa A0A287B198 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa A0A287B198 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa A0A287B198 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa A0A287B198 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa A0A287B198 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa A0A287B198 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa A0A287B198 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa A0A287B198 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa A0A287B198 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa A0A287B199 R-SSC-198983 https://reactome.org/PathwayBrowser/#/R-SSC-198983 NKG2D homodimer interacting with ligands IEA Sus scrofa A0A287B1A4 R-SSC-2468039 https://reactome.org/PathwayBrowser/#/R-SSC-2468039 Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 IEA Sus scrofa A0A287B1A4 R-SSC-2473152 https://reactome.org/PathwayBrowser/#/R-SSC-2473152 Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 IEA Sus scrofa A0A287B1B1 R-SSC-9609921 https://reactome.org/PathwayBrowser/#/R-SSC-9609921 SGTA binds Tail-anchored protein IEA Sus scrofa A0A287B1C5 R-SSC-195251 https://reactome.org/PathwayBrowser/#/R-SSC-195251 Assembly of the destruction complex IEA Sus scrofa A0A287B1C5 R-SSC-195275 https://reactome.org/PathwayBrowser/#/R-SSC-195275 Phosphorylation of APC component of the destruction complex IEA Sus scrofa A0A287B1C5 R-SSC-195280 https://reactome.org/PathwayBrowser/#/R-SSC-195280 Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex IEA Sus scrofa A0A287B1C5 R-SSC-195283 https://reactome.org/PathwayBrowser/#/R-SSC-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Sus scrofa A0A287B1C5 R-SSC-195287 https://reactome.org/PathwayBrowser/#/R-SSC-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Sus scrofa A0A287B1C5 R-SSC-195300 https://reactome.org/PathwayBrowser/#/R-SSC-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Sus scrofa A0A287B1C5 R-SSC-195304 https://reactome.org/PathwayBrowser/#/R-SSC-195304 Association of beta-catenin with the destruction complex IEA Sus scrofa A0A287B1C5 R-SSC-195318 https://reactome.org/PathwayBrowser/#/R-SSC-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Sus scrofa A0A287B1C5 R-SSC-201685 https://reactome.org/PathwayBrowser/#/R-SSC-201685 Beta-catenin is released from the destruction complex IEA Sus scrofa A0A287B1C5 R-SSC-202947 https://reactome.org/PathwayBrowser/#/R-SSC-202947 Caspase mediated cleavage of APC IEA Sus scrofa A0A287B1C5 R-SSC-2130279 https://reactome.org/PathwayBrowser/#/R-SSC-2130279 Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex IEA Sus scrofa A0A287B1C5 R-SSC-2130282 https://reactome.org/PathwayBrowser/#/R-SSC-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Sus scrofa A0A287B1C5 R-SSC-2130286 https://reactome.org/PathwayBrowser/#/R-SSC-2130286 Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) IEA Sus scrofa A0A287B1C5 R-SSC-3361751 https://reactome.org/PathwayBrowser/#/R-SSC-3361751 beta-catenin is replaced by repression complexes at the promoter IEA Sus scrofa A0A287B1C5 R-SSC-5229343 https://reactome.org/PathwayBrowser/#/R-SSC-5229343 AXIN is phosphorylated in the destruction complex IEA Sus scrofa A0A287B1C5 R-SSC-6781905 https://reactome.org/PathwayBrowser/#/R-SSC-6781905 ZRANB1 binds APC IEA Sus scrofa A0A287B1D6 R-SSC-162730 https://reactome.org/PathwayBrowser/#/R-SSC-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Sus scrofa A0A287B1I6 R-SSC-189398 https://reactome.org/PathwayBrowser/#/R-SSC-189398 HMOX1 dimer, HMOX2 cleave heme IEA Sus scrofa A0A287B1I6 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A287B1I6 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa A0A287B1I7 R-SSC-9700701 https://reactome.org/PathwayBrowser/#/R-SSC-9700701 T-type VDCC bind T-type VDCC blockers IEA Sus scrofa A0A287B1J2 R-SSC-9018815 https://reactome.org/PathwayBrowser/#/R-SSC-9018815 RHOT1 binds effectors at the mitochondrial outer membrane IEA Sus scrofa A0A287B1J2 R-SSC-9018824 https://reactome.org/PathwayBrowser/#/R-SSC-9018824 RHOT2 binds effectors at the mitochondrial outer membrane IEA Sus scrofa A0A287B1J6 R-SSC-6786239 https://reactome.org/PathwayBrowser/#/R-SSC-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Sus scrofa A0A287B1K0 R-SSC-450690 https://reactome.org/PathwayBrowser/#/R-SSC-450690 hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 IEA Sus scrofa A0A287B1K0 R-SSC-450827 https://reactome.org/PathwayBrowser/#/R-SSC-450827 hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2 IEA Sus scrofa A0A287B1K0 R-SSC-451418 https://reactome.org/PathwayBrowser/#/R-SSC-451418 Pellino ubiquitinates IRAK1 IEA Sus scrofa A0A287B1K0 R-SSC-8948063 https://reactome.org/PathwayBrowser/#/R-SSC-8948063 hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1 IEA Sus scrofa A0A287B1K0 R-SSC-8948066 https://reactome.org/PathwayBrowser/#/R-SSC-8948066 K63polyUb-IRAK1 dissociates IEA Sus scrofa A0A287B1K0 R-SSC-937034 https://reactome.org/PathwayBrowser/#/R-SSC-937034 IRAK1 phosphorylates Pellino IEA Sus scrofa A0A287B1K0 R-SSC-937044 https://reactome.org/PathwayBrowser/#/R-SSC-937044 Pellino binds hp-IRAK1:TRAF6 IEA Sus scrofa A0A287B1K0 R-SSC-937050 https://reactome.org/PathwayBrowser/#/R-SSC-937050 Pellino ubiquitinates hp-IRAK1 IEA Sus scrofa A0A287B1K0 R-SSC-975122 https://reactome.org/PathwayBrowser/#/R-SSC-975122 Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
IEA Sus scrofa A0A287B1K0 R-SSC-975139 https://reactome.org/PathwayBrowser/#/R-SSC-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation IEA Sus scrofa A0A287B1K0 R-SSC-975142 https://reactome.org/PathwayBrowser/#/R-SSC-975142 Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation IEA Sus scrofa A0A287B1L3 R-SSC-6799761 https://reactome.org/PathwayBrowser/#/R-SSC-6799761 TP53 binds PPP1R13L IEA Sus scrofa A0A287B1R0 R-SSC-390593 https://reactome.org/PathwayBrowser/#/R-SSC-390593 ATP Hydrolysis By Myosin IEA Sus scrofa A0A287B1R0 R-SSC-390595 https://reactome.org/PathwayBrowser/#/R-SSC-390595 Calcium Binds Troponin-C IEA Sus scrofa A0A287B1R0 R-SSC-390597 https://reactome.org/PathwayBrowser/#/R-SSC-390597 Release Of ADP From Myosin IEA Sus scrofa A0A287B1R0 R-SSC-390598 https://reactome.org/PathwayBrowser/#/R-SSC-390598 Myosin Binds ATP IEA Sus scrofa A0A287B1T2 R-SSC-1011576 https://reactome.org/PathwayBrowser/#/R-SSC-1011576 EHD proteins interact with Rabenosyn-5 IEA Sus scrofa A0A287B1T9 R-SSC-5685607 https://reactome.org/PathwayBrowser/#/R-SSC-5685607 Sialic acid binds SIGLEC IEA Sus scrofa A0A287B1T9 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A287B1U2 R-SSC-4551724 https://reactome.org/PathwayBrowser/#/R-SSC-4551724 PIAS4 SUMOylates HERC2 with SUMO1 IEA Sus scrofa A0A287B1U2 R-SSC-5682586 https://reactome.org/PathwayBrowser/#/R-SSC-5682586 HERC2 and PIAS4 are recruited to DNA DSBs IEA Sus scrofa A0A287B1U2 R-SSC-5682598 https://reactome.org/PathwayBrowser/#/R-SSC-5682598 ATM phosphorylates HERC2 IEA Sus scrofa A0A287B1U2 R-SSC-5682607 https://reactome.org/PathwayBrowser/#/R-SSC-5682607 PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs IEA Sus scrofa A0A287B1U2 R-SSC-5682858 https://reactome.org/PathwayBrowser/#/R-SSC-5682858 RNF8 and RNF168 ubiquitinate H2AFX IEA Sus scrofa A0A287B1U2 R-SSC-5682863 https://reactome.org/PathwayBrowser/#/R-SSC-5682863 RNF168 binds DNA DSBs IEA Sus scrofa A0A287B1U2 R-SSC-5683077 https://reactome.org/PathwayBrowser/#/R-SSC-5683077 RNF8 and RNF168 ubiquitinate KDM4A,B IEA Sus scrofa A0A287B1U2 R-SSC-5683384 https://reactome.org/PathwayBrowser/#/R-SSC-5683384 UIMC1 and FAM175A bind DNA DSBs IEA Sus scrofa A0A287B1U2 R-SSC-5683385 https://reactome.org/PathwayBrowser/#/R-SSC-5683385 Formation of BRCA1-A complex at DNA DSBs IEA Sus scrofa A0A287B1U2 R-SSC-5683405 https://reactome.org/PathwayBrowser/#/R-SSC-5683405 PPP5C dephosphorylates TP53BP1 IEA Sus scrofa A0A287B1U2 R-SSC-5683425 https://reactome.org/PathwayBrowser/#/R-SSC-5683425 ATM phosphorylates TP53BP1 at DNA DSBs IEA Sus scrofa A0A287B1U2 R-SSC-5683735 https://reactome.org/PathwayBrowser/#/R-SSC-5683735 CHEK2 is recruited to DNA DSBs IEA Sus scrofa A0A287B1U2 R-SSC-5683801 https://reactome.org/PathwayBrowser/#/R-SSC-5683801 CHEK2 phosphorylates BRCA1 IEA Sus scrofa A0A287B1U2 R-SSC-5684052 https://reactome.org/PathwayBrowser/#/R-SSC-5684052 PIAS4 SUMOylates MDC1 IEA Sus scrofa A0A287B1U2 R-SSC-5686685 https://reactome.org/PathwayBrowser/#/R-SSC-5686685 RIF1 and PAX1IP bind TP53BP1 at DNA DSBs IEA Sus scrofa A0A287B1U2 R-SSC-5686704 https://reactome.org/PathwayBrowser/#/R-SSC-5686704 Activated ATM phosphorylates DCLRE1C IEA Sus scrofa A0A287B1U2 R-SSC-5686900 https://reactome.org/PathwayBrowser/#/R-SSC-5686900 TP53BP1 recruits DCLRE1C to ATM IEA Sus scrofa A0A287B1U2 R-SSC-5693551 https://reactome.org/PathwayBrowser/#/R-SSC-5693551 Phosphorylation of BRCA1-A complex at multiple sites by ATM IEA Sus scrofa A0A287B1U2 R-SSC-5693566 https://reactome.org/PathwayBrowser/#/R-SSC-5693566 TP53BP1 associates with H4K20Me2 at DNA DSBs IEA Sus scrofa A0A287B1U2 R-SSC-69891 https://reactome.org/PathwayBrowser/#/R-SSC-69891 Phosphorylation and activation of CHEK2 by ATM IEA Sus scrofa A0A287B1U2 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287B1U2 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287B1U2 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287B1U2 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287B1U5 R-SSC-8952618 https://reactome.org/PathwayBrowser/#/R-SSC-8952618 AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287B1U5 R-SSC-8952626 https://reactome.org/PathwayBrowser/#/R-SSC-8952626 AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex IEA Sus scrofa A0A287B1U5 R-SSC-8952631 https://reactome.org/PathwayBrowser/#/R-SSC-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex IEA Sus scrofa A0A287B1U5 R-SSC-8952638 https://reactome.org/PathwayBrowser/#/R-SSC-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287B1U5 R-SSC-8955285 https://reactome.org/PathwayBrowser/#/R-SSC-8955285 COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287B1U5 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287B1U5 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287B1U5 R-SSC-8956045 https://reactome.org/PathwayBrowser/#/R-SSC-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287B1U5 R-SSC-8956099 https://reactome.org/PathwayBrowser/#/R-SSC-8956099 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 IEA Sus scrofa A0A287B1U5 R-SSC-8956103 https://reactome.org/PathwayBrowser/#/R-SSC-8956103 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha IEA Sus scrofa A0A287B1U5 R-SSC-8956106 https://reactome.org/PathwayBrowser/#/R-SSC-8956106 VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha IEA Sus scrofa A0A287B1U5 R-SSC-8956200 https://reactome.org/PathwayBrowser/#/R-SSC-8956200 MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex IEA Sus scrofa A0A287B1U5 R-SSC-9755303 https://reactome.org/PathwayBrowser/#/R-SSC-9755303 26S proteasome degrades HIFalpha IEA Sus scrofa A0A287B1V1 R-SSC-70800 https://reactome.org/PathwayBrowser/#/R-SSC-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Sus scrofa A0A287B1V1 R-SSC-9838081 https://reactome.org/PathwayBrowser/#/R-SSC-9838081 LONP1 degrades mitochondrial matrix proteins IEA Sus scrofa A0A287B1V1 R-SSC-9838093 https://reactome.org/PathwayBrowser/#/R-SSC-9838093 LONP1 binds mitochondrial matrix proteins IEA Sus scrofa A0A287B1V5 R-SSC-5690043 https://reactome.org/PathwayBrowser/#/R-SSC-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa A0A287B1X2 R-SSC-6798751 https://reactome.org/PathwayBrowser/#/R-SSC-6798751 Exocytosis of azurophil granule lumen proteins IEA Sus scrofa A0A287B1Y4 R-SSC-1112666 https://reactome.org/PathwayBrowser/#/R-SSC-1112666 BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate IEA Sus scrofa A0A287B1Y4 R-SSC-166753 https://reactome.org/PathwayBrowser/#/R-SSC-166753 Conversion of C4 into C4a and C4b IEA Sus scrofa A0A287B1Y4 R-SSC-166792 https://reactome.org/PathwayBrowser/#/R-SSC-166792 Conversion of C2 into C2a and C2b IEA Sus scrofa A0A287B1Y4 R-SSC-173626 https://reactome.org/PathwayBrowser/#/R-SSC-173626 Activation of C1r IEA Sus scrofa A0A287B1Y4 R-SSC-173631 https://reactome.org/PathwayBrowser/#/R-SSC-173631 Activation of C1s IEA Sus scrofa A0A287B1Y4 R-SSC-1861621 https://reactome.org/PathwayBrowser/#/R-SSC-1861621 Cross-linking of FCGRIIA with IgG-coated Ag IEA Sus scrofa A0A287B1Y4 R-SSC-199161 https://reactome.org/PathwayBrowser/#/R-SSC-199161 Fc gamma receptors interact with antigen-bound IgG IEA Sus scrofa A0A287B1Y4 R-SSC-2029268 https://reactome.org/PathwayBrowser/#/R-SSC-2029268 Phosphorylation and activation of PLCG IEA Sus scrofa A0A287B1Y4 R-SSC-2029270 https://reactome.org/PathwayBrowser/#/R-SSC-2029270 Recruitment of PLCgamma to membrane IEA Sus scrofa A0A287B1Y4 R-SSC-2029271 https://reactome.org/PathwayBrowser/#/R-SSC-2029271 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287B1Y4 R-SSC-2029272 https://reactome.org/PathwayBrowser/#/R-SSC-2029272 Release of PLCG from FCGR IEA Sus scrofa A0A287B1Y4 R-SSC-2029273 https://reactome.org/PathwayBrowser/#/R-SSC-2029273 PI3K binds to p-6Y-SYK IEA Sus scrofa A0A287B1Y4 R-SSC-2029451 https://reactome.org/PathwayBrowser/#/R-SSC-2029451 Activation of RAC1 by VAV IEA Sus scrofa A0A287B1Y4 R-SSC-2029452 https://reactome.org/PathwayBrowser/#/R-SSC-2029452 Recruitment of SYK to phosphorylated ITAMs IEA Sus scrofa A0A287B1Y4 R-SSC-2029453 https://reactome.org/PathwayBrowser/#/R-SSC-2029453 Phosphorylation of VAV IEA Sus scrofa A0A287B1Y4 R-SSC-2029455 https://reactome.org/PathwayBrowser/#/R-SSC-2029455 Cross-linking of FCGRIA with IgG-coated Ag IEA Sus scrofa A0A287B1Y4 R-SSC-2029457 https://reactome.org/PathwayBrowser/#/R-SSC-2029457 Cross-linking of FCGRIIIA with IgG-coated Ag IEA Sus scrofa A0A287B1Y4 R-SSC-2029458 https://reactome.org/PathwayBrowser/#/R-SSC-2029458 Recruitment of VAV1 to p-6Y-SYK IEA Sus scrofa A0A287B1Y4 R-SSC-2029459 https://reactome.org/PathwayBrowser/#/R-SSC-2029459 Sequestering and phosphorylation Fc gamma receptors in the lipid rafts IEA Sus scrofa A0A287B1Y4 R-SSC-2029467 https://reactome.org/PathwayBrowser/#/R-SSC-2029467 Activation of RAC1 by CRKII:DOCK180:ELMO IEA Sus scrofa A0A287B1Y4 R-SSC-2029476 https://reactome.org/PathwayBrowser/#/R-SSC-2029476 Role of myosins in phagosome formation IEA Sus scrofa A0A287B1Y4 R-SSC-2197697 https://reactome.org/PathwayBrowser/#/R-SSC-2197697 Recruitment of CRKII:DOCK180:ELMO complex to FCGR IEA Sus scrofa A0A287B1Y4 R-SSC-2203516 https://reactome.org/PathwayBrowser/#/R-SSC-2203516 Alpha-1-Microglobulin is cleaved IEA Sus scrofa A0A287B1Y4 R-SSC-2454192 https://reactome.org/PathwayBrowser/#/R-SSC-2454192 Allergen dependent IgE bound FCERI aggregation IEA Sus scrofa A0A287B1Y4 R-SSC-2454208 https://reactome.org/PathwayBrowser/#/R-SSC-2454208 Phosphorylation of beta and gamma subunits by LYN IEA Sus scrofa A0A287B1Y4 R-SSC-2454240 https://reactome.org/PathwayBrowser/#/R-SSC-2454240 Recruitment of SYK to p-FCERI gamma subunit IEA Sus scrofa A0A287B1Y4 R-SSC-2730833 https://reactome.org/PathwayBrowser/#/R-SSC-2730833 Phosphorylation of TEC kinases by p-SYK IEA Sus scrofa A0A287B1Y4 R-SSC-2730843 https://reactome.org/PathwayBrowser/#/R-SSC-2730843 Phosphorylation of LAT by p-SYK IEA Sus scrofa A0A287B1Y4 R-SSC-2730851 https://reactome.org/PathwayBrowser/#/R-SSC-2730851 Phosphorylation of SLP-76 by p-SYK IEA Sus scrofa A0A287B1Y4 R-SSC-2730882 https://reactome.org/PathwayBrowser/#/R-SSC-2730882 Phosphorylation of PKC-theta IEA Sus scrofa A0A287B1Y4 R-SSC-2730884 https://reactome.org/PathwayBrowser/#/R-SSC-2730884 Phosphorylation of NTAL by p-SYK/Lyn IEA Sus scrofa A0A287B1Y4 R-SSC-2730886 https://reactome.org/PathwayBrowser/#/R-SSC-2730886 Phosphorylation of SHC by SYK kinase IEA Sus scrofa A0A287B1Y4 R-SSC-5690701 https://reactome.org/PathwayBrowser/#/R-SSC-5690701 SHP1 binds p-CD22 IEA Sus scrofa A0A287B1Y4 R-SSC-5690702 https://reactome.org/PathwayBrowser/#/R-SSC-5690702 LYN phosphorylates CD22 IEA Sus scrofa A0A287B1Y4 R-SSC-5690740 https://reactome.org/PathwayBrowser/#/R-SSC-5690740 CD22 binds B-cell receptor IEA Sus scrofa A0A287B1Y4 R-SSC-8852266 https://reactome.org/PathwayBrowser/#/R-SSC-8852266 C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s IEA Sus scrofa A0A287B1Y4 R-SSC-8852481 https://reactome.org/PathwayBrowser/#/R-SSC-8852481 Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates IEA Sus scrofa A0A287B1Y4 R-SSC-8858428 https://reactome.org/PathwayBrowser/#/R-SSC-8858428 FCAMR binds IgA IEA Sus scrofa A0A287B1Y4 R-SSC-9021306 https://reactome.org/PathwayBrowser/#/R-SSC-9021306 C1-Inh binds and inactivates C1r, C1s IEA Sus scrofa A0A287B1Y4 R-SSC-9606151 https://reactome.org/PathwayBrowser/#/R-SSC-9606151 Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 IEA Sus scrofa A0A287B1Y4 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa A0A287B1Y4 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa A0A287B1Y4 R-SSC-9725206 https://reactome.org/PathwayBrowser/#/R-SSC-9725206 IgE binds FCERI IEA Sus scrofa A0A287B1Y4 R-SSC-983696 https://reactome.org/PathwayBrowser/#/R-SSC-983696 The Immunoglobulin of the BCR binds antigen IEA Sus scrofa A0A287B1Y4 R-SSC-983700 https://reactome.org/PathwayBrowser/#/R-SSC-983700 SYK binds the activated BCR IEA Sus scrofa A0A287B1Y4 R-SSC-983703 https://reactome.org/PathwayBrowser/#/R-SSC-983703 p-6Y-SYK phosphorylates BLNK (SLP65) IEA Sus scrofa A0A287B1Y4 R-SSC-983707 https://reactome.org/PathwayBrowser/#/R-SSC-983707 SYK autophosphorylates at the activated BCR IEA Sus scrofa A0A287B1Z2 R-SSC-418582 https://reactome.org/PathwayBrowser/#/R-SSC-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Sus scrofa A0A287B1Z2 R-SSC-8982012 https://reactome.org/PathwayBrowser/#/R-SSC-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Sus scrofa A0A287B1Z2 R-SSC-8982017 https://reactome.org/PathwayBrowser/#/R-SSC-8982017 Active G alpha (q) binds RGS proteins IEA Sus scrofa A0A287B1Z2 R-SSC-8982019 https://reactome.org/PathwayBrowser/#/R-SSC-8982019 Active G alpha (i)–i1/i2/i3 binds RGS proteins IEA Sus scrofa A0A287B1Z2 R-SSC-8982020 https://reactome.org/PathwayBrowser/#/R-SSC-8982020 G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated IEA Sus scrofa A0A287B1Z2 R-SSC-8982025 https://reactome.org/PathwayBrowser/#/R-SSC-8982025 G alpha (q) in G (q):RGS complex is inactivated IEA Sus scrofa A0A287B1Z2 R-SSC-8982026 https://reactome.org/PathwayBrowser/#/R-SSC-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Sus scrofa A0A287B203 R-SSC-170120 https://reactome.org/PathwayBrowser/#/R-SSC-170120 Translocation of Cdc25B to the cytoplasm IEA Sus scrofa A0A287B203 R-SSC-170153 https://reactome.org/PathwayBrowser/#/R-SSC-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Sus scrofa A0A287B203 R-SSC-170159 https://reactome.org/PathwayBrowser/#/R-SSC-170159 Translocation of Cdc25 to the nucleus IEA Sus scrofa A0A287B203 R-SSC-170161 https://reactome.org/PathwayBrowser/#/R-SSC-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Sus scrofa A0A287B203 R-SSC-174110 https://reactome.org/PathwayBrowser/#/R-SSC-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Sus scrofa A0A287B203 R-SSC-9929935 https://reactome.org/PathwayBrowser/#/R-SSC-9929935 CCNA:CDK1 phosphorylates CDC25B IEA Sus scrofa A0A287B207 R-SSC-8852129 https://reactome.org/PathwayBrowser/#/R-SSC-8852129 UBA1 conjugates ubiquitin to cytosolic E2 enzymes IEA Sus scrofa A0A287B207 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287B207 R-SSC-983152 https://reactome.org/PathwayBrowser/#/R-SSC-983152 Transfer of ubiquitin from E1 to E2 IEA Sus scrofa A0A287B207 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287B207 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287B224 R-SSC-5696358 https://reactome.org/PathwayBrowser/#/R-SSC-5696358 TREM,CD300 binds lipids IEA Sus scrofa A0A287B226 R-SSC-5250209 https://reactome.org/PathwayBrowser/#/R-SSC-5250209 ARL2:GTP:ARL2BP binds SLC25A4 IEA Sus scrofa A0A287B226 R-SSC-5250210 https://reactome.org/PathwayBrowser/#/R-SSC-5250210 ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix IEA Sus scrofa A0A287B226 R-SSC-5250217 https://reactome.org/PathwayBrowser/#/R-SSC-5250217 ARL2:GTP binds ARL2BP IEA Sus scrofa A0A287B226 R-SSC-5672027 https://reactome.org/PathwayBrowser/#/R-SSC-5672027 ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane IEA Sus scrofa A0A287B226 R-SSC-9654523 https://reactome.org/PathwayBrowser/#/R-SSC-9654523 ARL2:GTP bind PDE6D on KRAS4B IEA Sus scrofa A0A287B226 R-SSC-9654533 https://reactome.org/PathwayBrowser/#/R-SSC-9654533 KRAS4B recycles to the plasma membrane IEA Sus scrofa A0A287B227 R-SSC-5675376 https://reactome.org/PathwayBrowser/#/R-SSC-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Sus scrofa A0A287B229 R-SSC-5623524 https://reactome.org/PathwayBrowser/#/R-SSC-5623524 The exocyst complex binds to RAB3IP in the ciliary targeting complex IEA Sus scrofa A0A287B229 R-SSC-5623527 https://reactome.org/PathwayBrowser/#/R-SSC-5623527 VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane IEA Sus scrofa A0A287B231 R-SSC-8866275 https://reactome.org/PathwayBrowser/#/R-SSC-8866275 UBQLNs bind UIM-containing adaptor proteins IEA Sus scrofa A0A287B239 R-SSC-1605624 https://reactome.org/PathwayBrowser/#/R-SSC-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Sus scrofa A0A287B239 R-SSC-1606312 https://reactome.org/PathwayBrowser/#/R-SSC-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Sus scrofa A0A287B239 R-SSC-1630306 https://reactome.org/PathwayBrowser/#/R-SSC-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Sus scrofa A0A287B239 R-SSC-2090079 https://reactome.org/PathwayBrowser/#/R-SSC-2090079 GLB1 hydrolyses linker chain(2) IEA Sus scrofa A0A287B239 R-SSC-9840795 https://reactome.org/PathwayBrowser/#/R-SSC-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Sus scrofa A0A287B244 R-SSC-4411373 https://reactome.org/PathwayBrowser/#/R-SSC-4411373 NLK translocates to nucleus IEA Sus scrofa A0A287B244 R-SSC-4411383 https://reactome.org/PathwayBrowser/#/R-SSC-4411383 NLK phosphorylates TCF/LEF IEA Sus scrofa A0A287B244 R-SSC-4411402 https://reactome.org/PathwayBrowser/#/R-SSC-4411402 Activation of NLK IEA Sus scrofa A0A287B274 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A287B274 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A287B274 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A287B274 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A287B274 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A287B274 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A287B274 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A287B274 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A287B274 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A287B274 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287B274 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A287B274 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A287B274 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287B274 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A287B274 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287B274 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287B274 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287B274 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287B274 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287B274 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A287B274 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A287B280 R-SSC-5685318 https://reactome.org/PathwayBrowser/#/R-SSC-5685318 BCDX2 complex formation IEA Sus scrofa A0A287B280 R-SSC-5685341 https://reactome.org/PathwayBrowser/#/R-SSC-5685341 BCDX2 complex stabilizes RAD51 filament IEA Sus scrofa A0A287B280 R-SSC-5685838 https://reactome.org/PathwayBrowser/#/R-SSC-5685838 CX3 complex binds D-loop structures IEA Sus scrofa A0A287B280 R-SSC-5686440 https://reactome.org/PathwayBrowser/#/R-SSC-5686440 MUS81:EME1,EME2 cleaves D-loop IEA Sus scrofa A0A287B280 R-SSC-5693539 https://reactome.org/PathwayBrowser/#/R-SSC-5693539 Ligation of DNA and formation of Holliday structures following repair synthesis IEA Sus scrofa A0A287B280 R-SSC-5693584 https://reactome.org/PathwayBrowser/#/R-SSC-5693584 Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) IEA Sus scrofa A0A287B280 R-SSC-5693593 https://reactome.org/PathwayBrowser/#/R-SSC-5693593 D-loop extension by DNA polymerases IEA Sus scrofa A0A287B280 R-SSC-5693620 https://reactome.org/PathwayBrowser/#/R-SSC-5693620 D-loop formation mediated by PALB2, BRCA2 and RAD51 IEA Sus scrofa A0A287B280 R-SSC-9853389 https://reactome.org/PathwayBrowser/#/R-SSC-9853389 FIGNL1 binds RAD51 IEA Sus scrofa A0A287B286 R-SSC-1667005 https://reactome.org/PathwayBrowser/#/R-SSC-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Sus scrofa A0A287B286 R-SSC-1678694 https://reactome.org/PathwayBrowser/#/R-SSC-1678694 Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans IEA Sus scrofa A0A287B286 R-SSC-1878002 https://reactome.org/PathwayBrowser/#/R-SSC-1878002 XYLTs transfer Xyl to core protein IEA Sus scrofa A0A287B286 R-SSC-1889955 https://reactome.org/PathwayBrowser/#/R-SSC-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker IEA Sus scrofa A0A287B286 R-SSC-1889978 https://reactome.org/PathwayBrowser/#/R-SSC-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker IEA Sus scrofa A0A287B286 R-SSC-1889981 https://reactome.org/PathwayBrowser/#/R-SSC-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker IEA Sus scrofa A0A287B286 R-SSC-2022851 https://reactome.org/PathwayBrowser/#/R-SSC-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain IEA Sus scrofa A0A287B286 R-SSC-2022856 https://reactome.org/PathwayBrowser/#/R-SSC-2022856 EXT1:EXT2 transfers GlcNAc to heparan IEA Sus scrofa A0A287B286 R-SSC-2022860 https://reactome.org/PathwayBrowser/#/R-SSC-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) IEA Sus scrofa A0A287B286 R-SSC-2022887 https://reactome.org/PathwayBrowser/#/R-SSC-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Sus scrofa A0A287B286 R-SSC-2022919 https://reactome.org/PathwayBrowser/#/R-SSC-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue IEA Sus scrofa A0A287B286 R-SSC-2024084 https://reactome.org/PathwayBrowser/#/R-SSC-2024084 HS-GAGs translocate to the lysosome for degradation IEA Sus scrofa A0A287B286 R-SSC-2024108 https://reactome.org/PathwayBrowser/#/R-SSC-2024108 Some HSPGs are secreted to the plasma membrane IEA Sus scrofa A0A287B286 R-SSC-2076383 https://reactome.org/PathwayBrowser/#/R-SSC-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate IEA Sus scrofa A0A287B286 R-SSC-2076392 https://reactome.org/PathwayBrowser/#/R-SSC-2076392 EXT1:EXT2 transfers GlcA to heparan IEA Sus scrofa A0A287B286 R-SSC-2076419 https://reactome.org/PathwayBrowser/#/R-SSC-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin IEA Sus scrofa A0A287B286 R-SSC-2076508 https://reactome.org/PathwayBrowser/#/R-SSC-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate IEA Sus scrofa A0A287B286 R-SSC-2076611 https://reactome.org/PathwayBrowser/#/R-SSC-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate IEA Sus scrofa A0A287B286 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa A0A287B286 R-SSC-2423785 https://reactome.org/PathwayBrowser/#/R-SSC-2423785 CR:atREs binds apoE and HSPG IEA Sus scrofa A0A287B286 R-SSC-2684507 https://reactome.org/PathwayBrowser/#/R-SSC-2684507 Syndecans 1, 2, 4, (3) bind FGF2 IEA Sus scrofa A0A287B286 R-SSC-2731122 https://reactome.org/PathwayBrowser/#/R-SSC-2731122 Syndecans 1, 2 & 4 bind VTN IEA Sus scrofa A0A287B286 R-SSC-8870732 https://reactome.org/PathwayBrowser/#/R-SSC-8870732 PSGs bind proteoglycans and TGF-beta1 IEA Sus scrofa A0A287B286 R-SSC-9638064 https://reactome.org/PathwayBrowser/#/R-SSC-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker IEA Sus scrofa A0A287B2A0 R-SSC-606287 https://reactome.org/PathwayBrowser/#/R-SSC-606287 RSF complex binds the centromere IEA Sus scrofa A0A287B2A0 R-SSC-606326 https://reactome.org/PathwayBrowser/#/R-SSC-606326 HJURP:CENPA complex localizes to the centromere IEA Sus scrofa A0A287B2A0 R-SSC-606349 https://reactome.org/PathwayBrowser/#/R-SSC-606349 Mis18 complex binds the centromere IEA Sus scrofa A0A287B2C5 R-SSC-2990833 https://reactome.org/PathwayBrowser/#/R-SSC-2990833 Conjugation of SUMO1 to UBA2:SAE1 IEA Sus scrofa A0A287B2C5 R-SSC-2993780 https://reactome.org/PathwayBrowser/#/R-SSC-2993780 Transfer of SUMO1 from E1 to UBE2I (UBC9) IEA Sus scrofa A0A287B2D4 R-SSC-6814549 https://reactome.org/PathwayBrowser/#/R-SSC-6814549 Pre-snRNA transcript initiation, Integrator binding, LEC binding IEA Sus scrofa A0A287B2D4 R-SSC-6814555 https://reactome.org/PathwayBrowser/#/R-SSC-6814555 Integrator complex processes the 3' end of snRNA IEA Sus scrofa A0A287B2D4 R-SSC-6814559 https://reactome.org/PathwayBrowser/#/R-SSC-6814559 Pre-snRNA is elongated and capped with 7-methylguanosine IEA Sus scrofa A0A287B2D4 R-SSC-6814885 https://reactome.org/PathwayBrowser/#/R-SSC-6814885 CBCAP complex binds 7-methylguanosine cap of snRNA IEA Sus scrofa A0A287B2D7 R-SSC-162721 https://reactome.org/PathwayBrowser/#/R-SSC-162721 dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose IEA Sus scrofa A0A287B2D7 R-SSC-162730 https://reactome.org/PathwayBrowser/#/R-SSC-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Sus scrofa A0A287B2E7 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287B2F2 R-SSC-5675373 https://reactome.org/PathwayBrowser/#/R-SSC-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Sus scrofa A0A287B2G3 R-SSC-5694583 https://reactome.org/PathwayBrowser/#/R-SSC-5694583 ABHD4 hydrolyses NAPE IEA Sus scrofa A0A287B2H4 R-SSC-382054 https://reactome.org/PathwayBrowser/#/R-SSC-382054 PDGF binds to extracellular matrix proteins IEA Sus scrofa A0A287B2H4 R-SSC-5173005 https://reactome.org/PathwayBrowser/#/R-SSC-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Sus scrofa A0A287B2H4 R-SSC-5173192 https://reactome.org/PathwayBrowser/#/R-SSC-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Sus scrofa A0A287B2L2 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287B2L2 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287B2L2 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287B2L2 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287B2N9 R-SSC-5693742 https://reactome.org/PathwayBrowser/#/R-SSC-5693742 FAAH hydrolyses AEA to AA and ETA IEA Sus scrofa A0A287B2P3 R-SSC-6797554 https://reactome.org/PathwayBrowser/#/R-SSC-6797554 ABP1 binds SHANK proteins IEA Sus scrofa A0A287B2P5 R-SSC-170153 https://reactome.org/PathwayBrowser/#/R-SSC-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Sus scrofa A0A287B2P5 R-SSC-170158 https://reactome.org/PathwayBrowser/#/R-SSC-170158 CDC25A dephosphorylates CCNA:CDK1 IEA Sus scrofa A0A287B2P5 R-SSC-170159 https://reactome.org/PathwayBrowser/#/R-SSC-170159 Translocation of Cdc25 to the nucleus IEA Sus scrofa A0A287B2P5 R-SSC-174110 https://reactome.org/PathwayBrowser/#/R-SSC-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Sus scrofa A0A287B2P5 R-SSC-5696600 https://reactome.org/PathwayBrowser/#/R-SSC-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Sus scrofa A0A287B2P5 R-SSC-69199 https://reactome.org/PathwayBrowser/#/R-SSC-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Sus scrofa A0A287B2P5 R-SSC-69600 https://reactome.org/PathwayBrowser/#/R-SSC-69600 Proteolytic degradation of ubiquitinated-Cdc25A IEA Sus scrofa A0A287B2P5 R-SSC-69604 https://reactome.org/PathwayBrowser/#/R-SSC-69604 Phosphorylation of Cdc25A at Ser-123 by Chk1 IEA Sus scrofa A0A287B2P5 R-SSC-69608 https://reactome.org/PathwayBrowser/#/R-SSC-69608 Phosphorylation of Cdc25A at Ser-123 by Chk2 IEA Sus scrofa A0A287B2P9 R-SSC-8940388 https://reactome.org/PathwayBrowser/#/R-SSC-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Sus scrofa A0A287B2Q0 R-SSC-1234159 https://reactome.org/PathwayBrowser/#/R-SSC-1234159 Proteasome proteolyzes ub-HIF-alpha IEA Sus scrofa A0A287B2Q0 R-SSC-1234161 https://reactome.org/PathwayBrowser/#/R-SSC-1234161 HIF-alpha translocates from cytosol to nucleus IEA Sus scrofa A0A287B2Q0 R-SSC-1234163 https://reactome.org/PathwayBrowser/#/R-SSC-1234163 Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha IEA Sus scrofa A0A287B2Q0 R-SSC-1234164 https://reactome.org/PathwayBrowser/#/R-SSC-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Sus scrofa A0A287B2Q0 R-SSC-1234167 https://reactome.org/PathwayBrowser/#/R-SSC-1234167 Formation of HIF:CBP:p300 complex at promoters IEA Sus scrofa A0A287B2Q0 R-SSC-1234169 https://reactome.org/PathwayBrowser/#/R-SSC-1234169 Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Sus scrofa A0A287B2Q0 R-SSC-1234171 https://reactome.org/PathwayBrowser/#/R-SSC-1234171 HIF-alpha binds ARNT (HIF1-beta) forming HIF-alpha:ARNT IEA Sus scrofa A0A287B2Q0 R-SSC-1234172 https://reactome.org/PathwayBrowser/#/R-SSC-1234172 Nuclear VBC complex ubiquitinylates HIF-alpha IEA Sus scrofa A0A287B2Q0 R-SSC-1234175 https://reactome.org/PathwayBrowser/#/R-SSC-1234175 ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol IEA Sus scrofa A0A287B2Q0 R-SSC-1234177 https://reactome.org/PathwayBrowser/#/R-SSC-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Sus scrofa A0A287B2Q0 R-SSC-1234181 https://reactome.org/PathwayBrowser/#/R-SSC-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Sus scrofa A0A287B2Q0 R-SSC-1234183 https://reactome.org/PathwayBrowser/#/R-SSC-1234183 Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha IEA Sus scrofa A0A287B2Q0 R-SSC-6781797 https://reactome.org/PathwayBrowser/#/R-SSC-6781797 USP19 binds HIF1A,BIRC2,BIRC3 IEA Sus scrofa A0A287B2Q0 R-SSC-8857583 https://reactome.org/PathwayBrowser/#/R-SSC-8857583 LINC01139 promotes phosphorylation of HIF1A by PTK6 IEA Sus scrofa A0A287B2Q0 R-SSC-8956103 https://reactome.org/PathwayBrowser/#/R-SSC-8956103 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha IEA Sus scrofa A0A287B2Q0 R-SSC-8956106 https://reactome.org/PathwayBrowser/#/R-SSC-8956106 VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha IEA Sus scrofa A0A287B2Q0 R-SSC-9634702 https://reactome.org/PathwayBrowser/#/R-SSC-9634702 LINC01139 promotes phosphorylation of HIF1A by LRRK2 IEA Sus scrofa A0A287B2Q0 R-SSC-9755303 https://reactome.org/PathwayBrowser/#/R-SSC-9755303 26S proteasome degrades HIFalpha IEA Sus scrofa A0A287B2Q3 R-SSC-5672966 https://reactome.org/PathwayBrowser/#/R-SSC-5672966 RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers IEA Sus scrofa A0A287B2Q3 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A287B2Q3 R-SSC-9014449 https://reactome.org/PathwayBrowser/#/R-SSC-9014449 RHOG binds effectors at the plasma membrane IEA Sus scrofa A0A287B2Q3 R-SSC-9018794 https://reactome.org/PathwayBrowser/#/R-SSC-9018794 RHOV binds effectors at the plasma membrane IEA Sus scrofa A0A287B2Q4 R-SSC-2574840 https://reactome.org/PathwayBrowser/#/R-SSC-2574840 AJUBA facilitates AURKA autophosphorylation IEA Sus scrofa A0A287B2Q4 R-SSC-2574845 https://reactome.org/PathwayBrowser/#/R-SSC-2574845 AJUBA binds centrosome-associated AURKA IEA Sus scrofa A0A287B2Q4 R-SSC-3000310 https://reactome.org/PathwayBrowser/#/R-SSC-3000310 AURKA phosphorylates PLK1 IEA Sus scrofa A0A287B2Q4 R-SSC-3000319 https://reactome.org/PathwayBrowser/#/R-SSC-3000319 BORA binds PLK1 and AURKA IEA Sus scrofa A0A287B2Q4 R-SSC-380272 https://reactome.org/PathwayBrowser/#/R-SSC-380272 Plk1-mediated phosphorylation of Nlp IEA Sus scrofa A0A287B2Q4 R-SSC-380283 https://reactome.org/PathwayBrowser/#/R-SSC-380283 Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome IEA Sus scrofa A0A287B2Q4 R-SSC-380294 https://reactome.org/PathwayBrowser/#/R-SSC-380294 Loss of C-Nap-1 from centrosomes IEA Sus scrofa A0A287B2Q4 R-SSC-380303 https://reactome.org/PathwayBrowser/#/R-SSC-380303 Dissociation of Phospho-Nlp from the centrosome IEA Sus scrofa A0A287B2Q4 R-SSC-380311 https://reactome.org/PathwayBrowser/#/R-SSC-380311 Recruitment of Plk1 to centrosomes IEA Sus scrofa A0A287B2Q4 R-SSC-380316 https://reactome.org/PathwayBrowser/#/R-SSC-380316 Association of NuMA with microtubules IEA Sus scrofa A0A287B2Q4 R-SSC-380455 https://reactome.org/PathwayBrowser/#/R-SSC-380455 Recruitment of CDK11p58 to the centrosomes IEA Sus scrofa A0A287B2Q4 R-SSC-380508 https://reactome.org/PathwayBrowser/#/R-SSC-380508 Translocation of NuMA to the centrosomes IEA Sus scrofa A0A287B2Q4 R-SSC-5617816 https://reactome.org/PathwayBrowser/#/R-SSC-5617816 RAB3IP stimulates nucleotide exchange on RAB8A IEA Sus scrofa A0A287B2Q4 R-SSC-5626220 https://reactome.org/PathwayBrowser/#/R-SSC-5626220 C2CD3 binds the mother centriole IEA Sus scrofa A0A287B2Q4 R-SSC-5626223 https://reactome.org/PathwayBrowser/#/R-SSC-5626223 C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole IEA Sus scrofa A0A287B2Q4 R-SSC-5626228 https://reactome.org/PathwayBrowser/#/R-SSC-5626228 The distal appendage proteins recruit TTBK2 IEA Sus scrofa A0A287B2Q4 R-SSC-5626681 https://reactome.org/PathwayBrowser/#/R-SSC-5626681 Recruitment of transition zone proteins IEA Sus scrofa A0A287B2Q4 R-SSC-5626699 https://reactome.org/PathwayBrowser/#/R-SSC-5626699 MARK4 binds ODF2 in the centriole IEA Sus scrofa A0A287B2Q4 R-SSC-5638009 https://reactome.org/PathwayBrowser/#/R-SSC-5638009 CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body IEA Sus scrofa A0A287B2Q4 R-SSC-8853405 https://reactome.org/PathwayBrowser/#/R-SSC-8853405 TPX2 binds AURKA at centrosomes IEA Sus scrofa A0A287B2Q4 R-SSC-8853419 https://reactome.org/PathwayBrowser/#/R-SSC-8853419 TPX2 promotes AURKA autophosphorylation IEA Sus scrofa A0A287B2S7 R-SSC-6794347 https://reactome.org/PathwayBrowser/#/R-SSC-6794347 Homer1,2,3 dimerizes IEA Sus scrofa A0A287B2S7 R-SSC-6794355 https://reactome.org/PathwayBrowser/#/R-SSC-6794355 Homer1,2,3 binds mGluR1a,5 IEA Sus scrofa A0A287B2U1 R-SSC-111930 https://reactome.org/PathwayBrowser/#/R-SSC-111930 Adenylate cyclase produces cAMP IEA Sus scrofa A0A287B2U1 R-SSC-170666 https://reactome.org/PathwayBrowser/#/R-SSC-170666 Adenylate cyclase increases the GTPase activity of G alpha-olf IEA Sus scrofa A0A287B2U1 R-SSC-170671 https://reactome.org/PathwayBrowser/#/R-SSC-170671 G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex IEA Sus scrofa A0A287B2U1 R-SSC-170672 https://reactome.org/PathwayBrowser/#/R-SSC-170672 Galpha-olf:GTP binds to adenylate cyclase and activates it IEA Sus scrofa A0A287B2U1 R-SSC-170674 https://reactome.org/PathwayBrowser/#/R-SSC-170674 Dissociation of the Gi alpha:G olf complex IEA Sus scrofa A0A287B2U1 R-SSC-170676 https://reactome.org/PathwayBrowser/#/R-SSC-170676 Adenylate cyclase converts ATP into cyclic AMP IEA Sus scrofa A0A287B2U1 R-SSC-170677 https://reactome.org/PathwayBrowser/#/R-SSC-170677 The G alpha-olf:GDP:Adenylate cyclase complex dissociates IEA Sus scrofa A0A287B2U1 R-SSC-170685 https://reactome.org/PathwayBrowser/#/R-SSC-170685 Adenylaye cyclase increases the GTPase activity of G alpha-olf IEA Sus scrofa A0A287B2U1 R-SSC-170686 https://reactome.org/PathwayBrowser/#/R-SSC-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Sus scrofa A0A287B2U1 R-SSC-392064 https://reactome.org/PathwayBrowser/#/R-SSC-392064 G alpha (z) inhibits adenylate cyclase IEA Sus scrofa A0A287B2U1 R-SSC-5610727 https://reactome.org/PathwayBrowser/#/R-SSC-5610727 GPR161 promotes cAMP production in a G alpha(s)-dependent manner IEA Sus scrofa A0A287B2V7 R-SSC-9844006 https://reactome.org/PathwayBrowser/#/R-SSC-9844006 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) IEA Sus scrofa A0A287B2V7 R-SSC-9844057 https://reactome.org/PathwayBrowser/#/R-SSC-9844057 SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome IEA Sus scrofa A0A287B2W3 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A287B2W3 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A287B2W3 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A287B2W3 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A287B2W3 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A287B2X0 R-SSC-5333678 https://reactome.org/PathwayBrowser/#/R-SSC-5333678 CPNEs bind PL IEA Sus scrofa A0A287B2X0 R-SSC-6798739 https://reactome.org/PathwayBrowser/#/R-SSC-6798739 Exocytosis of azurophil granule membrane proteins IEA Sus scrofa A0A287B2X3 R-SSC-204169 https://reactome.org/PathwayBrowser/#/R-SSC-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Sus scrofa A0A287B310 R-SSC-6798739 https://reactome.org/PathwayBrowser/#/R-SSC-6798739 Exocytosis of azurophil granule membrane proteins IEA Sus scrofa A0A287B310 R-SSC-6798747 https://reactome.org/PathwayBrowser/#/R-SSC-6798747 Exocytosis of tertiary granule membrane proteins IEA Sus scrofa A0A287B310 R-SSC-6799350 https://reactome.org/PathwayBrowser/#/R-SSC-6799350 Exocytosis of specific granule membrane proteins IEA Sus scrofa A0A287B310 R-SSC-8863494 https://reactome.org/PathwayBrowser/#/R-SSC-8863494 ASICs bind STOML3, (STOM) IEA Sus scrofa A0A287B310 R-SSC-9013009 https://reactome.org/PathwayBrowser/#/R-SSC-9013009 RHOA binds effectors at the plasma membrane IEA Sus scrofa A0A287B310 R-SSC-9013024 https://reactome.org/PathwayBrowser/#/R-SSC-9013024 RHOB binds effectors at the plasma membrane IEA Sus scrofa A0A287B310 R-SSC-9013110 https://reactome.org/PathwayBrowser/#/R-SSC-9013110 RHOC binds effectors at the plasma membrane IEA Sus scrofa A0A287B310 R-SSC-9013157 https://reactome.org/PathwayBrowser/#/R-SSC-9013157 CDC42 binds effectors at the plasma membrane IEA Sus scrofa A0A287B310 R-SSC-9018746 https://reactome.org/PathwayBrowser/#/R-SSC-9018746 RHOQ binds effectors at the plasma membrane IEA Sus scrofa A0A287B310 R-SSC-9018758 https://reactome.org/PathwayBrowser/#/R-SSC-9018758 RHOH binds effectors at the plasma membrane IEA Sus scrofa A0A287B316 R-SSC-8952638 https://reactome.org/PathwayBrowser/#/R-SSC-8952638 AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287B316 R-SSC-8955245 https://reactome.org/PathwayBrowser/#/R-SSC-8955245 CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus IEA Sus scrofa A0A287B316 R-SSC-8955285 https://reactome.org/PathwayBrowser/#/R-SSC-8955285 COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287B316 R-SSC-8956045 https://reactome.org/PathwayBrowser/#/R-SSC-8956045 COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex IEA Sus scrofa A0A287B320 R-SSC-376419 https://reactome.org/PathwayBrowser/#/R-SSC-376419 Formation of NR-MED1 Coactivator Complex IEA Sus scrofa A0A287B320 R-SSC-382096 https://reactome.org/PathwayBrowser/#/R-SSC-382096 Formation of NR-NCOR Corepressor Complex IEA Sus scrofa A0A287B322 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287B322 R-SSC-9842833 https://reactome.org/PathwayBrowser/#/R-SSC-9842833 SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes IEA Sus scrofa A0A287B327 R-SSC-2002428 https://reactome.org/PathwayBrowser/#/R-SSC-2002428 Removal of fibrillar collagen N-propeptides IEA Sus scrofa A0A287B327 R-SSC-5173005 https://reactome.org/PathwayBrowser/#/R-SSC-5173005 B3GALTL transfers glucose to O-fucosyl-proteins IEA Sus scrofa A0A287B327 R-SSC-5173192 https://reactome.org/PathwayBrowser/#/R-SSC-5173192 POFUT2 transfers fucose to TSR domain-containing proteins IEA Sus scrofa A0A287B341 R-SSC-2509793 https://reactome.org/PathwayBrowser/#/R-SSC-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Sus scrofa A0A287B341 R-SSC-2509816 https://reactome.org/PathwayBrowser/#/R-SSC-2509816 NUDT16 hydrolyses IDP to IMP IEA Sus scrofa A0A287B356 R-SSC-204617 https://reactome.org/PathwayBrowser/#/R-SSC-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Sus scrofa A0A287B356 R-SSC-204647 https://reactome.org/PathwayBrowser/#/R-SSC-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Sus scrofa A0A287B356 R-SSC-204662 https://reactome.org/PathwayBrowser/#/R-SSC-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Sus scrofa A0A287B3A4 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa A0A287B3A4 R-SSC-392054 https://reactome.org/PathwayBrowser/#/R-SSC-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras IEA Sus scrofa A0A287B3A4 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287B3A4 R-SSC-6807875 https://reactome.org/PathwayBrowser/#/R-SSC-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex IEA Sus scrofa A0A287B3A4 R-SSC-6807877 https://reactome.org/PathwayBrowser/#/R-SSC-6807877 ARFGAPs stimulate ARF GTPase activity IEA Sus scrofa A0A287B3A4 R-SSC-6809003 https://reactome.org/PathwayBrowser/#/R-SSC-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin IEA Sus scrofa A0A287B3A4 R-SSC-6809006 https://reactome.org/PathwayBrowser/#/R-SSC-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex IEA Sus scrofa A0A287B3A4 R-SSC-6809011 https://reactome.org/PathwayBrowser/#/R-SSC-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle IEA Sus scrofa A0A287B3A6 R-SSC-9861563 https://reactome.org/PathwayBrowser/#/R-SSC-9861563 CTLH E3 ligase ubiquitinates LDHA IEA Sus scrofa A0A287B3A6 R-SSC-9861640 https://reactome.org/PathwayBrowser/#/R-SSC-9861640 CTLH E3 ligase ubiquitinates PKM-1 IEA Sus scrofa A0A287B3C2 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287B3C3 R-SSC-196857 https://reactome.org/PathwayBrowser/#/R-SSC-196857 PANK2 phosphorylates PanK IEA Sus scrofa A0A287B3D4 R-SSC-163090 https://reactome.org/PathwayBrowser/#/R-SSC-163090 Elongation Of The Telomeric Chromosome End IEA Sus scrofa A0A287B3D4 R-SSC-163096 https://reactome.org/PathwayBrowser/#/R-SSC-163096 Recruitment of Telomerase RNP to the Telomeric Chromosome End IEA Sus scrofa A0A287B3D4 R-SSC-163099 https://reactome.org/PathwayBrowser/#/R-SSC-163099 Alignment Of The RNA Template On The Telomeric Chromosome End IEA Sus scrofa A0A287B3D4 R-SSC-163120 https://reactome.org/PathwayBrowser/#/R-SSC-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Sus scrofa A0A287B3D4 R-SSC-164617 https://reactome.org/PathwayBrowser/#/R-SSC-164617 Elongation of Extended Telomeric Chromosome End IEA Sus scrofa A0A287B3D4 R-SSC-164620 https://reactome.org/PathwayBrowser/#/R-SSC-164620 Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End IEA Sus scrofa A0A287B3E0 R-SSC-5665802 https://reactome.org/PathwayBrowser/#/R-SSC-5665802 SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin IEA Sus scrofa A0A287B3E0 R-SSC-5665809 https://reactome.org/PathwayBrowser/#/R-SSC-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Sus scrofa A0A287B3E0 R-SSC-9013144 https://reactome.org/PathwayBrowser/#/R-SSC-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Sus scrofa A0A287B3E0 R-SSC-9013161 https://reactome.org/PathwayBrowser/#/R-SSC-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Sus scrofa A0A287B3E0 R-SSC-9018745 https://reactome.org/PathwayBrowser/#/R-SSC-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Sus scrofa A0A287B3E0 R-SSC-9018766 https://reactome.org/PathwayBrowser/#/R-SSC-9018766 RHOU binds effectors at the plasma membrane IEA Sus scrofa A0A287B3E0 R-SSC-9018806 https://reactome.org/PathwayBrowser/#/R-SSC-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Sus scrofa A0A287B3E0 R-SSC-9693282 https://reactome.org/PathwayBrowser/#/R-SSC-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Sus scrofa A0A287B3F4 R-SSC-6798748 https://reactome.org/PathwayBrowser/#/R-SSC-6798748 Exocytosis of secretory granule lumen proteins IEA Sus scrofa A0A287B3F4 R-SSC-6800434 https://reactome.org/PathwayBrowser/#/R-SSC-6800434 Exocytosis of ficolin-rich granule lumen proteins IEA Sus scrofa A0A287B3F4 R-SSC-71552 https://reactome.org/PathwayBrowser/#/R-SSC-71552 limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin IEA Sus scrofa A0A287B3F4 R-SSC-71593 https://reactome.org/PathwayBrowser/#/R-SSC-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Sus scrofa A0A287B3H7 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287B3H7 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287B3H7 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287B3H7 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287B3H8 R-SSC-3215448 https://reactome.org/PathwayBrowser/#/R-SSC-3215448 SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity IEA Sus scrofa A0A287B3H8 R-SSC-5205799 https://reactome.org/PathwayBrowser/#/R-SSC-5205799 CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) IEA Sus scrofa A0A287B3H8 R-SSC-5205861 https://reactome.org/PathwayBrowser/#/R-SSC-5205861 COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) IEA Sus scrofa A0A287B3H8 R-SSC-8938217 https://reactome.org/PathwayBrowser/#/R-SSC-8938217 RUNX1 binds the SWI/SNF complex IEA Sus scrofa A0A287B3H8 R-SSC-9933237 https://reactome.org/PathwayBrowser/#/R-SSC-9933237 PBRM1-containing ATPase complex binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD&:PHF10 IEA Sus scrofa A0A287B3I8 R-SSC-191972 https://reactome.org/PathwayBrowser/#/R-SSC-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Sus scrofa A0A287B3I8 R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa A0A287B3I8 R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa A0A287B3I8 R-SSC-194187 https://reactome.org/PathwayBrowser/#/R-SSC-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Sus scrofa A0A287B3I8 R-SSC-200406 https://reactome.org/PathwayBrowser/#/R-SSC-200406 CPT1A transfers PALM to CAR IEA Sus scrofa A0A287B3I8 R-SSC-376419 https://reactome.org/PathwayBrowser/#/R-SSC-376419 Formation of NR-MED1 Coactivator Complex IEA Sus scrofa A0A287B3I8 R-SSC-381262 https://reactome.org/PathwayBrowser/#/R-SSC-381262 Formation of PPARG:RXRA heterodimer (ARF6 complex) IEA Sus scrofa A0A287B3I8 R-SSC-382096 https://reactome.org/PathwayBrowser/#/R-SSC-382096 Formation of NR-NCOR Corepressor Complex IEA Sus scrofa A0A287B3I8 R-SSC-400183 https://reactome.org/PathwayBrowser/#/R-SSC-400183 PPARA:RXRA binds Corepressors of PPARA IEA Sus scrofa A0A287B3I8 R-SSC-400204 https://reactome.org/PathwayBrowser/#/R-SSC-400204 PPARA binds RXRA IEA Sus scrofa A0A287B3I8 R-SSC-4341048 https://reactome.org/PathwayBrowser/#/R-SSC-4341048 SUMOylation of RXRA with SUMO1 IEA Sus scrofa A0A287B3I8 R-SSC-5334854 https://reactome.org/PathwayBrowser/#/R-SSC-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Sus scrofa A0A287B3I8 R-SSC-5340251 https://reactome.org/PathwayBrowser/#/R-SSC-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 IEA Sus scrofa A0A287B3I8 R-SSC-5422942 https://reactome.org/PathwayBrowser/#/R-SSC-5422942 RXRA:PPARD binds FABP5:atRA IEA Sus scrofa A0A287B3I8 R-SSC-5634100 https://reactome.org/PathwayBrowser/#/R-SSC-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Sus scrofa A0A287B3I8 R-SSC-5634103 https://reactome.org/PathwayBrowser/#/R-SSC-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Sus scrofa A0A287B3I8 R-SSC-9009817 https://reactome.org/PathwayBrowser/#/R-SSC-9009817 Acitretin binds to RAR:RXR IEA Sus scrofa A0A287B3I8 R-SSC-9024326 https://reactome.org/PathwayBrowser/#/R-SSC-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Sus scrofa A0A287B3I8 R-SSC-9024334 https://reactome.org/PathwayBrowser/#/R-SSC-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Sus scrofa A0A287B3I8 R-SSC-9029517 https://reactome.org/PathwayBrowser/#/R-SSC-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Sus scrofa A0A287B3I8 R-SSC-9029551 https://reactome.org/PathwayBrowser/#/R-SSC-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Sus scrofa A0A287B3I8 R-SSC-9029561 https://reactome.org/PathwayBrowser/#/R-SSC-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Sus scrofa A0A287B3I8 R-SSC-9029566 https://reactome.org/PathwayBrowser/#/R-SSC-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Sus scrofa A0A287B3I8 R-SSC-9029580 https://reactome.org/PathwayBrowser/#/R-SSC-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Sus scrofa A0A287B3I8 R-SSC-9617067 https://reactome.org/PathwayBrowser/#/R-SSC-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Sus scrofa A0A287B3I8 R-SSC-9619756 https://reactome.org/PathwayBrowser/#/R-SSC-9619756 NR1H2 binds ABCA1 IEA Sus scrofa A0A287B3I8 R-SSC-9732629 https://reactome.org/PathwayBrowser/#/R-SSC-9732629 PPARG binds PPARG agonists IEA Sus scrofa A0A287B3I8 R-SSC-9734475 https://reactome.org/PathwayBrowser/#/R-SSC-9734475 PPARA binds fibrates IEA Sus scrofa A0A287B3I8 R-SSC-9843115 https://reactome.org/PathwayBrowser/#/R-SSC-9843115 Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci IEA Sus scrofa A0A287B3I8 R-SSC-9843117 https://reactome.org/PathwayBrowser/#/R-SSC-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Sus scrofa A0A287B3I8 R-SSC-9843118 https://reactome.org/PathwayBrowser/#/R-SSC-9843118 RXRA binds ligands IEA Sus scrofa A0A287B3I8 R-SSC-9843120 https://reactome.org/PathwayBrowser/#/R-SSC-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Sus scrofa A0A287B3J8 R-SSC-5336466 https://reactome.org/PathwayBrowser/#/R-SSC-5336466 MRS2 transports Mg2+ from cytosol to mitochondrial matrix IEA Sus scrofa A0A287B3M3 R-SSC-5624949 https://reactome.org/PathwayBrowser/#/R-SSC-5624949 Assembly of the anterograde IFT train IEA Sus scrofa A0A287B3M3 R-SSC-5624952 https://reactome.org/PathwayBrowser/#/R-SSC-5624952 Assembly of the retrograde IFT train IEA Sus scrofa A0A287B3M3 R-SSC-5625416 https://reactome.org/PathwayBrowser/#/R-SSC-5625416 Anterograde IFT IEA Sus scrofa A0A287B3M3 R-SSC-5625421 https://reactome.org/PathwayBrowser/#/R-SSC-5625421 The anterograde IFT train dissociates IEA Sus scrofa A0A287B3M3 R-SSC-5625424 https://reactome.org/PathwayBrowser/#/R-SSC-5625424 The retrograde IFT train dissociates IEA Sus scrofa A0A287B3M3 R-SSC-5625426 https://reactome.org/PathwayBrowser/#/R-SSC-5625426 Retrograde IFT IEA Sus scrofa A0A287B3M4 R-SSC-141409 https://reactome.org/PathwayBrowser/#/R-SSC-141409 Mad1 binds kinetochore IEA Sus scrofa A0A287B3M4 R-SSC-141422 https://reactome.org/PathwayBrowser/#/R-SSC-141422 MAD2 converted to an inhibitory state via interaction with Mad1 IEA Sus scrofa A0A287B3M4 R-SSC-141431 https://reactome.org/PathwayBrowser/#/R-SSC-141431 MAD2 associates with the Mad1 kinetochore complex IEA Sus scrofa A0A287B3M4 R-SSC-141439 https://reactome.org/PathwayBrowser/#/R-SSC-141439 Release of activated MAD2 from kinetochores IEA Sus scrofa A0A287B3M4 R-SSC-1638803 https://reactome.org/PathwayBrowser/#/R-SSC-1638803 Phosphorylation of cohesin by PLK1 at centromeres IEA Sus scrofa A0A287B3M4 R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa A0A287B3M4 R-SSC-195251 https://reactome.org/PathwayBrowser/#/R-SSC-195251 Assembly of the destruction complex IEA Sus scrofa A0A287B3M4 R-SSC-195275 https://reactome.org/PathwayBrowser/#/R-SSC-195275 Phosphorylation of APC component of the destruction complex IEA Sus scrofa A0A287B3M4 R-SSC-195280 https://reactome.org/PathwayBrowser/#/R-SSC-195280 Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex IEA Sus scrofa A0A287B3M4 R-SSC-195283 https://reactome.org/PathwayBrowser/#/R-SSC-195283 Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 IEA Sus scrofa A0A287B3M4 R-SSC-195287 https://reactome.org/PathwayBrowser/#/R-SSC-195287 Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 IEA Sus scrofa A0A287B3M4 R-SSC-195300 https://reactome.org/PathwayBrowser/#/R-SSC-195300 Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 IEA Sus scrofa A0A287B3M4 R-SSC-195304 https://reactome.org/PathwayBrowser/#/R-SSC-195304 Association of beta-catenin with the destruction complex IEA Sus scrofa A0A287B3M4 R-SSC-195318 https://reactome.org/PathwayBrowser/#/R-SSC-195318 Phosphorylation of beta-catenin at Ser45 by CK1 alpha IEA Sus scrofa A0A287B3M4 R-SSC-201685 https://reactome.org/PathwayBrowser/#/R-SSC-201685 Beta-catenin is released from the destruction complex IEA Sus scrofa A0A287B3M4 R-SSC-2130279 https://reactome.org/PathwayBrowser/#/R-SSC-2130279 Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex IEA Sus scrofa A0A287B3M4 R-SSC-2130282 https://reactome.org/PathwayBrowser/#/R-SSC-2130282 Degradation of ubiquitinated beta catenin by the proteasome IEA Sus scrofa A0A287B3M4 R-SSC-2130286 https://reactome.org/PathwayBrowser/#/R-SSC-2130286 Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) IEA Sus scrofa A0A287B3M4 R-SSC-2467809 https://reactome.org/PathwayBrowser/#/R-SSC-2467809 ESPL1 (Separase) cleaves centromeric cohesin IEA Sus scrofa A0A287B3M4 R-SSC-2467811 https://reactome.org/PathwayBrowser/#/R-SSC-2467811 Separation of sister chromatids IEA Sus scrofa A0A287B3M4 R-SSC-2468287 https://reactome.org/PathwayBrowser/#/R-SSC-2468287 CDK1 phosphorylates CDCA5 (Sororin) at centromeres IEA Sus scrofa A0A287B3M4 R-SSC-2484822 https://reactome.org/PathwayBrowser/#/R-SSC-2484822 Kinetochore assembly IEA Sus scrofa A0A287B3M4 R-SSC-375302 https://reactome.org/PathwayBrowser/#/R-SSC-375302 Kinetochore capture of astral microtubules IEA Sus scrofa A0A287B3M4 R-SSC-388808 https://reactome.org/PathwayBrowser/#/R-SSC-388808 CD28 homodimer binds B7-2 monomer IEA Sus scrofa A0A287B3M4 R-SSC-388809 https://reactome.org/PathwayBrowser/#/R-SSC-388809 CTLA-4 binds B7-1/B7-2 IEA Sus scrofa A0A287B3M4 R-SSC-388811 https://reactome.org/PathwayBrowser/#/R-SSC-388811 CD28 homodimer binds B7-1 homodimer IEA Sus scrofa A0A287B3M4 R-SSC-388833 https://reactome.org/PathwayBrowser/#/R-SSC-388833 Phosphorylation of CTLA-4 IEA Sus scrofa A0A287B3M4 R-SSC-389532 https://reactome.org/PathwayBrowser/#/R-SSC-389532 PP2A binds CTLA4 dimer IEA Sus scrofa A0A287B3M4 R-SSC-432143 https://reactome.org/PathwayBrowser/#/R-SSC-432143 PECAM-1 binds PP2A IEA Sus scrofa A0A287B3M4 R-SSC-5229343 https://reactome.org/PathwayBrowser/#/R-SSC-5229343 AXIN is phosphorylated in the destruction complex IEA Sus scrofa A0A287B3M4 R-SSC-5666129 https://reactome.org/PathwayBrowser/#/R-SSC-5666129 CDC42:GTP recruits DIAPH2-2 to kinetochores IEA Sus scrofa A0A287B3M4 R-SSC-5666160 https://reactome.org/PathwayBrowser/#/R-SSC-5666160 AURKB phosphorylates DIAPH2-2 at kinetochores IEA Sus scrofa A0A287B3M4 R-SSC-5666169 https://reactome.org/PathwayBrowser/#/R-SSC-5666169 Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 IEA Sus scrofa A0A287B3M4 R-SSC-5672957 https://reactome.org/PathwayBrowser/#/R-SSC-5672957 PP2A dephosphorylates KSR1 IEA Sus scrofa A0A287B3M4 R-SSC-5672961 https://reactome.org/PathwayBrowser/#/R-SSC-5672961 PP2A dephosphorylates inactive RAFs IEA Sus scrofa A0A287B3M4 R-SSC-5675431 https://reactome.org/PathwayBrowser/#/R-SSC-5675431 PP2A dephosphorylates RAF1 IEA Sus scrofa A0A287B3M4 R-SSC-8857925 https://reactome.org/PathwayBrowser/#/R-SSC-8857925 Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 IEA Sus scrofa A0A287B3M4 R-SSC-9648114 https://reactome.org/PathwayBrowser/#/R-SSC-9648114 EML4 recruits NUDC to mitotic spindle IEA Sus scrofa A0A287B3R8 R-SSC-5419261 https://reactome.org/PathwayBrowser/#/R-SSC-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP IEA Sus scrofa A0A287B3R8 R-SSC-5419264 https://reactome.org/PathwayBrowser/#/R-SSC-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA IEA Sus scrofa A0A287B3R8 R-SSC-5419271 https://reactome.org/PathwayBrowser/#/R-SSC-5419271 55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed IEA Sus scrofa A0A287B3R8 R-SSC-5419273 https://reactome.org/PathwayBrowser/#/R-SSC-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits IEA Sus scrofa A0A287B3R8 R-SSC-5419281 https://reactome.org/PathwayBrowser/#/R-SSC-5419281 MRRF binds 55S ribosome:mRNA:tRNA IEA Sus scrofa A0A287B3T2 R-SSC-189465 https://reactome.org/PathwayBrowser/#/R-SSC-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Sus scrofa A0A287B3T2 R-SSC-9838035 https://reactome.org/PathwayBrowser/#/R-SSC-9838035 CLPXP binds mitochondrial matrix proteins IEA Sus scrofa A0A287B3T2 R-SSC-9838081 https://reactome.org/PathwayBrowser/#/R-SSC-9838081 LONP1 degrades mitochondrial matrix proteins IEA Sus scrofa A0A287B3T2 R-SSC-9838093 https://reactome.org/PathwayBrowser/#/R-SSC-9838093 LONP1 binds mitochondrial matrix proteins IEA Sus scrofa A0A287B3T2 R-SSC-9838289 https://reactome.org/PathwayBrowser/#/R-SSC-9838289 CLPXP degrades mitochondrial matrix proteins IEA Sus scrofa A0A287B3V5 R-SSC-109699 https://reactome.org/PathwayBrowser/#/R-SSC-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3 IEA Sus scrofa A0A287B3V5 R-SSC-1307955 https://reactome.org/PathwayBrowser/#/R-SSC-1307955 FGFR4 binds HS:KLB:FGF19 IEA Sus scrofa A0A287B3V5 R-SSC-1307963 https://reactome.org/PathwayBrowser/#/R-SSC-1307963 Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 IEA Sus scrofa A0A287B3V5 R-SSC-190265 https://reactome.org/PathwayBrowser/#/R-SSC-190265 FGFR4 binds to FGF IEA Sus scrofa A0A287B3V5 R-SSC-190326 https://reactome.org/PathwayBrowser/#/R-SSC-190326 Autocatalytic phosphorylation of FGFR4 IEA Sus scrofa A0A287B3V5 R-SSC-2316434 https://reactome.org/PathwayBrowser/#/R-SSC-2316434 PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287B3V5 R-SSC-5654151 https://reactome.org/PathwayBrowser/#/R-SSC-5654151 Activated FGFR4 phosphorylates PLCG1 IEA Sus scrofa A0A287B3V5 R-SSC-5654163 https://reactome.org/PathwayBrowser/#/R-SSC-5654163 Activated FGFR4 binds PLCG1 IEA Sus scrofa A0A287B3V5 R-SSC-5654169 https://reactome.org/PathwayBrowser/#/R-SSC-5654169 p-4Y-PLCG1 dissociates from activated FGFR4 IEA Sus scrofa A0A287B3V5 R-SSC-5654418 https://reactome.org/PathwayBrowser/#/R-SSC-5654418 Activated FGFR4 phosphorylates FRS2 IEA Sus scrofa A0A287B3V5 R-SSC-5654422 https://reactome.org/PathwayBrowser/#/R-SSC-5654422 Activated FGFR4 binds FRS2 IEA Sus scrofa A0A287B3V5 R-SSC-5654423 https://reactome.org/PathwayBrowser/#/R-SSC-5654423 Activated FGFR4:p-SHC1 binds GRB2:SOS1 IEA Sus scrofa A0A287B3V5 R-SSC-5654425 https://reactome.org/PathwayBrowser/#/R-SSC-5654425 Activated FGFR4 binds SHC1 IEA Sus scrofa A0A287B3V5 R-SSC-5654426 https://reactome.org/PathwayBrowser/#/R-SSC-5654426 Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A287B3V5 R-SSC-5654428 https://reactome.org/PathwayBrowser/#/R-SSC-5654428 Activated FGFR4 phosphorylates SHC1 IEA Sus scrofa A0A287B3V5 R-SSC-5654566 https://reactome.org/PathwayBrowser/#/R-SSC-5654566 Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2 IEA Sus scrofa A0A287B3V5 R-SSC-5654651 https://reactome.org/PathwayBrowser/#/R-SSC-5654651 Activated FGFR4 binds FRS3 IEA Sus scrofa A0A287B3V5 R-SSC-5654653 https://reactome.org/PathwayBrowser/#/R-SSC-5654653 Activated FGFR4 phosphorylates FRS3 IEA Sus scrofa A0A287B3V5 R-SSC-5654655 https://reactome.org/PathwayBrowser/#/R-SSC-5654655 Activated FGFR4 phosphorylates PPTN11 IEA Sus scrofa A0A287B3V5 R-SSC-5654658 https://reactome.org/PathwayBrowser/#/R-SSC-5654658 Activated FGFR4:p-FRS bind to PPTN11 IEA Sus scrofa A0A287B3V5 R-SSC-5654659 https://reactome.org/PathwayBrowser/#/R-SSC-5654659 Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 IEA Sus scrofa A0A287B3V5 R-SSC-5654662 https://reactome.org/PathwayBrowser/#/R-SSC-5654662 Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA IEA Sus scrofa A0A287B3V5 R-SSC-5654663 https://reactome.org/PathwayBrowser/#/R-SSC-5654663 Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange IEA Sus scrofa A0A287B3V5 R-SSC-5654664 https://reactome.org/PathwayBrowser/#/R-SSC-5654664 Activated FGFR4:p-FRS binds GRB2:SOS1 IEA Sus scrofa A0A287B3V5 R-SSC-5654667 https://reactome.org/PathwayBrowser/#/R-SSC-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 IEA Sus scrofa A0A287B3V5 R-SSC-5654669 https://reactome.org/PathwayBrowser/#/R-SSC-5654669 Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA IEA Sus scrofa A0A287B3V5 R-SSC-5654684 https://reactome.org/PathwayBrowser/#/R-SSC-5654684 CBL ubiquitinates FRS2 and FGFR4 IEA Sus scrofa A0A287B3V5 R-SSC-5654714 https://reactome.org/PathwayBrowser/#/R-SSC-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287B3V5 R-SSC-5654717 https://reactome.org/PathwayBrowser/#/R-SSC-5654717 FGFR4-associated PI3K phosphorylates PIP2 to PIP3 IEA Sus scrofa A0A287B3V5 R-SSC-5654734 https://reactome.org/PathwayBrowser/#/R-SSC-5654734 p-CBL:GRB2 binds p-FRS2:activated FGFR4 IEA Sus scrofa A0A287B3V5 R-SSC-5672965 https://reactome.org/PathwayBrowser/#/R-SSC-5672965 RAS GEFs promote RAS nucleotide exchange IEA Sus scrofa A0A287B3V5 R-SSC-8941613 https://reactome.org/PathwayBrowser/#/R-SSC-8941613 Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange IEA Sus scrofa A0A287B3Y5 R-SSC-73647 https://reactome.org/PathwayBrowser/#/R-SSC-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Sus scrofa A0A287B401 R-SSC-8938356 https://reactome.org/PathwayBrowser/#/R-SSC-8938356 RMB14 binds RUNX2 IEA Sus scrofa A0A287B402 R-SSC-9696267 https://reactome.org/PathwayBrowser/#/R-SSC-9696267 RND3 binds GTP IEA Sus scrofa A0A287B402 R-SSC-9696268 https://reactome.org/PathwayBrowser/#/R-SSC-9696268 RND3 binds effectors IEA Sus scrofa A0A287B419 R-SSC-210426 https://reactome.org/PathwayBrowser/#/R-SSC-210426 Glutamate synaptic vesicle docking and priming IEA Sus scrofa A0A287B419 R-SSC-210430 https://reactome.org/PathwayBrowser/#/R-SSC-210430 Release of L-Glutamate at the synapse IEA Sus scrofa A0A287B419 R-SSC-210444 https://reactome.org/PathwayBrowser/#/R-SSC-210444 L-Glutamate loading of synaptic vesicle IEA Sus scrofa A0A287B419 R-SSC-264615 https://reactome.org/PathwayBrowser/#/R-SSC-264615 Loading of acetylcholine in synaptic vesicles IEA Sus scrofa A0A287B419 R-SSC-372505 https://reactome.org/PathwayBrowser/#/R-SSC-372505 Acetylcholine synaptic vesicle docking and priming IEA Sus scrofa A0A287B419 R-SSC-372529 https://reactome.org/PathwayBrowser/#/R-SSC-372529 Release of acetylcholine at the synapse IEA Sus scrofa A0A287B419 R-SSC-374899 https://reactome.org/PathwayBrowser/#/R-SSC-374899 Release of noradrenaline at the synapse IEA Sus scrofa A0A287B419 R-SSC-374922 https://reactome.org/PathwayBrowser/#/R-SSC-374922 Noradrenalin synaptic vesicle docking and priming IEA Sus scrofa A0A287B419 R-SSC-380574 https://reactome.org/PathwayBrowser/#/R-SSC-380574 Dopamine synaptic vesicle docking and priming IEA Sus scrofa A0A287B419 R-SSC-380869 https://reactome.org/PathwayBrowser/#/R-SSC-380869 Release of docked dopamine loaded synaptic vesicle IEA Sus scrofa A0A287B419 R-SSC-380901 https://reactome.org/PathwayBrowser/#/R-SSC-380901 Release of docked serotonin loaded synaptic vesicle IEA Sus scrofa A0A287B419 R-SSC-380905 https://reactome.org/PathwayBrowser/#/R-SSC-380905 Serotonin loaded synaptic vesicle docking and priming IEA Sus scrofa A0A287B419 R-SSC-6798743 https://reactome.org/PathwayBrowser/#/R-SSC-6798743 Exocytosis of secretory granule membrane proteins IEA Sus scrofa A0A287B419 R-SSC-8875318 https://reactome.org/PathwayBrowser/#/R-SSC-8875318 RAB3 GEFs exchange GTP for GDP on RAB3A IEA Sus scrofa A0A287B419 R-SSC-888589 https://reactome.org/PathwayBrowser/#/R-SSC-888589 Release of GABA at the synapse IEA Sus scrofa A0A287B419 R-SSC-917744 https://reactome.org/PathwayBrowser/#/R-SSC-917744 GABA loaded synaptic vesicle Docking and Priming IEA Sus scrofa A0A287B431 R-SSC-3232162 https://reactome.org/PathwayBrowser/#/R-SSC-3232162 PIAS3 SUMOylates MITF with SUMO1 IEA Sus scrofa A0A287B431 R-SSC-9824977 https://reactome.org/PathwayBrowser/#/R-SSC-9824977 MAPK1-dependent phosphorylation of MITF-M IEA Sus scrofa A0A287B431 R-SSC-9824979 https://reactome.org/PathwayBrowser/#/R-SSC-9824979 XPO1 binds p-S69,73 MITF-M IEA Sus scrofa A0A287B431 R-SSC-9824986 https://reactome.org/PathwayBrowser/#/R-SSC-9824986 XPO1-dependent export of p-S69,S73 MITF-M IEA Sus scrofa A0A287B431 R-SSC-9824994 https://reactome.org/PathwayBrowser/#/R-SSC-9824994 RPS6KA1-dependent phosphorylation of MITF-M IEA Sus scrofa A0A287B431 R-SSC-9824995 https://reactome.org/PathwayBrowser/#/R-SSC-9824995 GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 IEA Sus scrofa A0A287B431 R-SSC-9824999 https://reactome.org/PathwayBrowser/#/R-SSC-9824999 GSK3B phosphorylates p-S73 MITF-M at residue S69 IEA Sus scrofa A0A287B431 R-SSC-9825751 https://reactome.org/PathwayBrowser/#/R-SSC-9825751 HINT1 binds MITF-M IEA Sus scrofa A0A287B431 R-SSC-9825754 https://reactome.org/PathwayBrowser/#/R-SSC-9825754 HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter IEA Sus scrofa A0A287B431 R-SSC-9825782 https://reactome.org/PathwayBrowser/#/R-SSC-9825782 p-S207 KARS1 dimer binds MITF-M:HINT1 dimer IEA Sus scrofa A0A287B431 R-SSC-9825788 https://reactome.org/PathwayBrowser/#/R-SSC-9825788 p-S207 KARS displaces HINT1 IEA Sus scrofa A0A287B431 R-SSC-9825790 https://reactome.org/PathwayBrowser/#/R-SSC-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Sus scrofa A0A287B431 R-SSC-9926476 https://reactome.org/PathwayBrowser/#/R-SSC-9926476 UBE2I sumoylates MITF-M IEA Sus scrofa A0A287B431 R-SSC-9926478 https://reactome.org/PathwayBrowser/#/R-SSC-9926478 MITF-M binds CREBBP,EP300 IEA Sus scrofa A0A287B431 R-SSC-9926483 https://reactome.org/PathwayBrowser/#/R-SSC-9926483 MARK3 phosphorylates MITF-M on S173 IEA Sus scrofa A0A287B441 R-SSC-164832 https://reactome.org/PathwayBrowser/#/R-SSC-164832 ATPase synthesizes ATP IEA Sus scrofa A0A287B441 R-SSC-164834 https://reactome.org/PathwayBrowser/#/R-SSC-164834 Enzyme-bound ATP is released IEA Sus scrofa A0A287B441 R-SSC-164840 https://reactome.org/PathwayBrowser/#/R-SSC-164840 ADP and Pi bind to ATPase IEA Sus scrofa A0A287B441 R-SSC-8949580 https://reactome.org/PathwayBrowser/#/R-SSC-8949580 F1Fo ATP synthase dimerizes IEA Sus scrofa A0A287B441 R-SSC-9837978 https://reactome.org/PathwayBrowser/#/R-SSC-9837978 LONP1 binds mitochondrial inner membrane proteins IEA Sus scrofa A0A287B441 R-SSC-9838004 https://reactome.org/PathwayBrowser/#/R-SSC-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Sus scrofa A0A287B448 R-SSC-1222516 https://reactome.org/PathwayBrowser/#/R-SSC-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Sus scrofa A0A287B448 R-SSC-5252133 https://reactome.org/PathwayBrowser/#/R-SSC-5252133 ATP6AP1 binds V-ATPase IEA Sus scrofa A0A287B448 R-SSC-74723 https://reactome.org/PathwayBrowser/#/R-SSC-74723 Endosome acidification IEA Sus scrofa A0A287B448 R-SSC-917841 https://reactome.org/PathwayBrowser/#/R-SSC-917841 Acidification of Tf:TfR1 containing endosome IEA Sus scrofa A0A287B448 R-SSC-9639286 https://reactome.org/PathwayBrowser/#/R-SSC-9639286 RRAGC,D exchanges GTP for GDP IEA Sus scrofa A0A287B448 R-SSC-9640167 https://reactome.org/PathwayBrowser/#/R-SSC-9640167 RRAGA,B exchanges GDP for GTP IEA Sus scrofa A0A287B448 R-SSC-9640168 https://reactome.org/PathwayBrowser/#/R-SSC-9640168 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine IEA Sus scrofa A0A287B448 R-SSC-9640175 https://reactome.org/PathwayBrowser/#/R-SSC-9640175 v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine IEA Sus scrofa A0A287B448 R-SSC-9640195 https://reactome.org/PathwayBrowser/#/R-SSC-9640195 RRAGA,B hydrolyzes GTP IEA Sus scrofa A0A287B448 R-SSC-9645598 https://reactome.org/PathwayBrowser/#/R-SSC-9645598 RRAGC,D hydrolyzes GTP IEA Sus scrofa A0A287B448 R-SSC-9645608 https://reactome.org/PathwayBrowser/#/R-SSC-9645608 v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 IEA Sus scrofa A0A287B448 R-SSC-9646468 https://reactome.org/PathwayBrowser/#/R-SSC-9646468 mTORC1 binds RHEB:GTP IEA Sus scrofa A0A287B467 R-SSC-8955241 https://reactome.org/PathwayBrowser/#/R-SSC-8955241 CAND1 binds cytosolic CRL E3 ubiquitin ligases IEA Sus scrofa A0A287B467 R-SSC-8955289 https://reactome.org/PathwayBrowser/#/R-SSC-8955289 COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287B467 R-SSC-8956040 https://reactome.org/PathwayBrowser/#/R-SSC-8956040 COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes IEA Sus scrofa A0A287B467 R-SSC-983140 https://reactome.org/PathwayBrowser/#/R-SSC-983140 Transfer of Ub from E2 to substrate and release of E2 IEA Sus scrofa A0A287B467 R-SSC-983147 https://reactome.org/PathwayBrowser/#/R-SSC-983147 Release of E3 from polyubiquitinated substrate IEA Sus scrofa A0A287B467 R-SSC-983156 https://reactome.org/PathwayBrowser/#/R-SSC-983156 Polyubiquitination of substrate IEA Sus scrofa A0A287B467 R-SSC-983157 https://reactome.org/PathwayBrowser/#/R-SSC-983157 Interaction of E3 with substrate and E2-Ub complex IEA Sus scrofa A0A287B475 R-SSC-418456 https://reactome.org/PathwayBrowser/#/R-SSC-418456 cGMP is degraded by PDEs IEA Sus scrofa A0A287B475 R-SSC-9018778 https://reactome.org/PathwayBrowser/#/R-SSC-9018778 RHOBTB1 binds interacting proteins at the endosome membrane IEA Sus scrofa A0A287B475 R-SSC-9708104 https://reactome.org/PathwayBrowser/#/R-SSC-9708104 PDE5A dimer binds PDE5A inhibitors IEA Sus scrofa A0A287B476 R-SSC-2454081 https://reactome.org/PathwayBrowser/#/R-SSC-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Sus scrofa A0A287B476 R-SSC-5362518 https://reactome.org/PathwayBrowser/#/R-SSC-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Sus scrofa A0A287B4A3 R-SSC-204617 https://reactome.org/PathwayBrowser/#/R-SSC-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Sus scrofa A0A287B4A3 R-SSC-204647 https://reactome.org/PathwayBrowser/#/R-SSC-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Sus scrofa A0A287B4A3 R-SSC-204662 https://reactome.org/PathwayBrowser/#/R-SSC-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Sus scrofa A0A287B4B5 R-SSC-964759 https://reactome.org/PathwayBrowser/#/R-SSC-964759 Alternative endo-mannosidase I route IEA Sus scrofa A0A287B4D1 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa A0A287B4F4 R-SSC-975040 https://reactome.org/PathwayBrowser/#/R-SSC-975040 KRAB-ZNF / KAP Interaction IEA Sus scrofa A0A287B4G0 R-SSC-209792 https://reactome.org/PathwayBrowser/#/R-SSC-209792 N-acetylation of serotonin IEA Sus scrofa A0A287B4H7 R-SSC-9865350 https://reactome.org/PathwayBrowser/#/R-SSC-9865350 Nascent MT-CO1 binds to MITRAC, Mg2+, PE, CL IEA Sus scrofa A0A287B4H7 R-SSC-9865412 https://reactome.org/PathwayBrowser/#/R-SSC-9865412 TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC IEA Sus scrofa A0A287B4H7 R-SSC-9865449 https://reactome.org/PathwayBrowser/#/R-SSC-9865449 Metallochaperone inserts Cu2+ into MT-CO1 IEA Sus scrofa A0A287B4H7 R-SSC-9865579 https://reactome.org/P